id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265499-pbf11zy1	Dove, Brian K.	Changes in nucleolar morphology and proteins during infection with the coronavirus infectious bronchitis virus	2006-03-03		.txt	text/plain	5026	250	46	In this study, using the avian infectious bronchitis coronavirus, we have shown that virus infection results in a number of changes to the nucleolus both in terms of gross morphology and protein content. Using IBV we tested the hypothesis that virus infection leads to perturbations in the morphology and proteins of the nucleolus which may have downstream consequences for host cell function. A change in the morphology of the nucleolus was observed in IBV-infected cells using EGFPnucleolin as a marker protein (e.g. Fig. 3B ), leading to the prediction that the levels of nucleolin might increase in virus-infected cells, which was observed in Fig. 4B . This study was undertaken with a higher resolution confocal microscope and we observed a third population of cells in which N protein was predominantly localized in the cytoplasm, but also was present in low levels in the nucleus and nucleolus (an example is shown in Fig. 7A) .	./cache/cord-265499-pbf11zy1.txt	./txt/cord-265499-pbf11zy1.txt