id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349500-603v8lfb	Neurath, Markus F	Covid-19 and immunomodulation in IBD	2020-04-16		.txt	text/plain	6548	386	45	Although covid-19 leads to little or mild flu-like symptoms in the majority of affected patients, the disease may cause severe, frequently lethal complications such as progressive pneumonia, acute respiratory distress syndrome and organ failure driven by hyperinflammation and a cytokine storm syndrome. Although covid-19 leads to little or mild flu-like symptoms in the majority of affected patients, the disease may cause severe, frequently lethal complications such as progressive pneumonia, acute respiratory distress syndrome and organ failure driven by hyperinflammation and a cytokine storm syndrome. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infects ACE2 expressing epithelial cells in the lung and/or the intestine. The covid-19 receptor ACE2 is particularly highly expressed in intestinal epithelial cells from the terminal ileum and to a lesser extent in the colon, where mucosal inflammation in patients with IBD (Crohn's disease (CD); UC) is frequently detected.	./cache/cord-349500-603v8lfb.txt	./txt/cord-349500-603v8lfb.txt