id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-288014-rrr4x755	Wang, Hong-Gang	Excessive anxiety in IBD patients is unnecessary for COVID-19	2020-05-12		.txt	text/plain	648	47	62	To the editor, Currently, 2019 novel coronavirus (SARS-CoV-2) infection disease (COVID-19) broke out in Wuhan, China and spread worldwide [1, 2] . Inflammatory bowel disease (IBD) is a chronic non-specific intestinal disease, including ulcerative colitis (UC) and Crohn's disease (CD), and many of these patients have anxiety [3] . Analysis of the transcriptome data of these samples, we found that the expression of ACE2 in the terminal ileum was significantly higher than that in the rectal colon, with a fold change of 9.8 times (P < 0.001). The expression of ACE2 in the UC rectum was not significantly higher than that in non-IBD. In the terminal ileum of CD, ACE2 expression was also not higher than that of non-IBD. These results indicate that the expression of ACE2 does not show a significant difference between IBD and non-IBD patients. Compared with non-IBD, there was no significant difference in TMPRSS2 expression in the rectum and terminal ileum of patients with IBD.	./cache/cord-288014-rrr4x755.txt	./txt/cord-288014-rrr4x755.txt