id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-285426-iyl12ber	Ghavami, Shaghayegh Baradaran	IBD Patients Could Be Silent Carriers for Novel Coronavirus and Less Prone to its Severe Adverse Events: True or False?	2020-09-08		.txt	text/plain	1967	111	47	Interestingly, in the recent pandemic of coronavirus disease (COVID19) , and the SARS-CoV epidemic in 2003, while the fecal samples of these patients were positive for the virus, they did not present any severe respiratory distress syndrome (4). Remarkably, the angiotensin-converting enzyme-2 (ACE2) is the receptor for SARS-CoV-2 and it is expressed in different organs including the lungs, testis and ileum. showed that when rheumatoid arthritis patients were treated with anti-TNF-α biologicals (infliximab, adalimumab, and certolizumab pegol), the expression of IFN-α-regulated genes was increased in the peripheral blood mononuclear cell (PBMC) compared to the control group. Besides, in IBD patients, particularly those who are under anti-TNF-α treatment, the host innate immune system interferes more efficiently with viral replication cycle and the clinical presentations are more moderate (9, 12) . Are patients with inflammatory bowel disease at increased risk for Covid-19 infection?	./cache/cord-285426-iyl12ber.txt	./txt/cord-285426-iyl12ber.txt