id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-340971-e42g37la	Lehrer, Robert I.	Defensins and Other Antimicrobial Peptides and Proteins	2007-05-09		.txt	text/plain	10442	579	40	In humans (and other mammals), defensins and cathelicidins are the principal antimicrobial peptides of neutrophils and epithelial cells. Defensins also induce the synthesis of interleukin-8 (IL-8), a C-X-C cytokine, by human airway epithelial cells, possibly providing a mechanism to recruit additional neutrophils to sites of inflammation (Van Wetering et al. In mice with a targeted disruption of the intestinal prodefensin-processing protease, matrilysin, Paneth cell defensin precursors were not processed to active mature peptides. Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene Human beta-defensin 4: A novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity Paneth cells of the human small intestine express an antimicrobial peptide gene In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils	./cache/cord-340971-e42g37la.txt	./txt/cord-340971-e42g37la.txt