id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295194-xbla6tu7	Stripecke, Renata	Innovations, challenges, and minimal information for standardization of humanized mice	2020-06-24		.txt	text/plain	9889	432	40	antibody-dependent cellular cytotoxicity, is an immune defense mechanism whereby effector cells such as NK cells lyses target cells that have been bound by specific antibodies AML acute myeloid leukemia ART anti-retroviral therapy BDBV Bundibugyo ebolavirus BiTE bispecific T-cell engagers is a registered trademark for a class of recombinant bispecific monoclonal antibodies which bind to the CD3 receptor and to a tumor-specific antigen BLT bone marrow-liver-thymus BM bone marrow bNAbs broadly neutralizing antibodies are antibodies capable of neutralizing different types of viral strains BRGF Balb/c Rag2 À/À Il2rg À/À Flt3 À/À mouse strain expressing macrophage colonystimulating factors (M-CSF), IL-3, IL-6, GM-CSF, and thrombopoietin (TPO) MSCs mesenchymal stromal cells Myelo-ablated mice are mice treated with irradiation or chemotherapy in order to decrease the bone marrow activity in order to improve the engraftment of transplanted stem cells Myelodysplasia is an abnormal accumulation of immature blood cells in the bone marrow Myelofibrosis is the replacement of the bone marrow with scar tissue due to proliferation of immature blood cells NASH non-alcoholic steatohepatitis NIH National Institutes of Health NK natural killer NOD Non-obese diabetic NOG NOD.Cg-Prkdc scid Il2rg tm1Sug /Jic NRGF NOD-Rag1 À/À Il2rg À/À Flk2 À/À NRG NOD-Rag1 tm1Mom Il2rg tm1Wjl /SzJ NSG NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ PBMCs peripheral blood mononuclear cells PD-1 programmed death receptor 1 PD-L1 PD-1 ligand 1 PDX-MI PDX Model Minimal Information standard PDX patient-derived xenograft PIRF POR À/À /Il2rg À/À /Rag2 À/À /FAH À/À Rag1 recombination activating gene Studies of human stem cell engraftment, hematopoiesis, and immunity	./cache/cord-295194-xbla6tu7.txt	./txt/cord-295194-xbla6tu7.txt