id author title date pages extension mime words sentences flesch summary cache txt cord-022381-x15ki4xv Goldblum, Randall M. Immunological Components of Milk: Formation and Function 2012-12-02 .txt text/plain 5886 323 49 Although the array and mechanisms of production of inflammatory mediators in the lactating mammary gland are not well understood, several cytokines that may be involved in leukocyte migration have been detected in human milk, as described in later sections of this chapter. Although the concentration of lymphocytes in human milk is small relative to that in peripheral blood, these cells are consistently present in milk obtained during the first few months of lactation. The demonstration of a very high density of IgAland IgA2-producing cells in the lactating mammary gland (Brandtzaeg, 1983) helps explain why human colostrum and milk contain the highest concentrations of SIgA of any secretions. The high proportion of SIgA in human milk of the IgA2 isotype (-40%) relative to plasma (10%) also must be related to the isotype distribution of these cells in the mammary gland. ./cache/cord-022381-x15ki4xv.txt ./txt/cord-022381-x15ki4xv.txt