id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007101-m0fs2f2a	Wang, Mei	Human Microbiota-Associated Swine: Current Progress and Future Opportunities	2015-05-19		.txt	text/plain	6496	331	37	Due to the high degree of similarity in anatomy, physiology, immunology and brain growth, the domestic pig (Sus scrofa) is considered a clinically relevant model to study factors influencing human gastrointestinal, immune, and brain development. Thus, the HMA pig model has the potential to be a valuable model for investigating how the gut microbiota composition changes in response to environmental factors, such as age, diet, vaccination, antibiotic use and infection. While differences between mother-fed or FF neonates of both species can be appreciated, marked differences in the gut microbiota Table 1 Advantages of the swine model • Omnivorousnutritional requirement and physiology similar to human • High genome and protein sequence similarities with human • Immune system more closely resembles human • Brain growth and development patterns similar to human ○ The major brain growth spurt similar to human ○ Gross anatomical features of the brain are comparable to that of human infants • Body sizeallowing various surgical manipulation and collection of adequate quantity of samples.	./cache/cord-007101-m0fs2f2a.txt	./txt/cord-007101-m0fs2f2a.txt