id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-018906-03nynqtq	Moulton, Bart	Pulmonary Complications	2014-11-25		.txt	text/plain	2864	217	45	After hematopoietic stem cell transplant (HSCT), up to 60 % of patients develop pulmonary complications. In spite of antibacterial, antiviral, and antifungal prophylaxis, reduced host defenses render the HSCT patient vulnerable to pulmonary and other infections in the early weeks and even months post-transplantation. This chapter suggests an integrative approach followed by a description of the most common pulmonary syndromes seen in HSCT patients, including diffuse alveolar hemorrhage (DAH), idiopathic pneumonia syndrome (IPS), bronchiolitis obliterans syndrome (BOS), and cryptogenic organizing pneumonia (COP). Two-year mortality after hematopoietic stem cell transplant (HSCT) has been estimated using a pre-transplantation assessment of mortality (PAM) score which incorporates spirometry and diffusing capacity variables in combination with the presence of renal and hepatic dysfunction, conditioning regimen, and disease risk. Diffuse alveolar hemorrhage (DAH) is a subset of pulmonary hemorrhage that can develop in up to 5 % of all post-HSCT recipients with mortality rates ranging between 50 and 80 % based on the two largest case series.	./cache/cord-018906-03nynqtq.txt	./txt/cord-018906-03nynqtq.txt