id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017883-6a4fkd5v	Dutta, Ankhi	Infection Prevention in Pediatric Oncology and Hematopoietic Stem Cell Transplant Recipients	2018-07-16		.txt	text/plain	6243	301	35	There are various factors which contribute to the increased susceptibility to infections in pediatric hematology/oncology (PHO) and HSCT patients, most prominent of them being disruption of cutaneous and mucosal barriers (oral, gastrointestinal, etc.), microbial gastrointestinal translocation, defects in cell-mediated immunity, and insufficient quantities and inadequate function of phagocytes. Based upon such data in adults, the IDSA Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer state that fluoroquinolone prophylaxis should be considered for high-risk patients with prolonged severe neutropenia [20] . Though some authors suggest that antibiotic prophylaxis should be considered in children undergoing induction chemotherapy for ALL, there is currently insufficient data to inform definitive guidelines for antibiotic prophylaxis to prevent bacterial infections in pediatric oncology patients [19] [20] [21] .	./cache/cord-017883-6a4fkd5v.txt	./txt/cord-017883-6a4fkd5v.txt