id author title date pages extension mime words sentences flesch summary cache txt cord-327701-1qgaxcqq Scott, E. M. Risk factors and patterns of household clusters of respiratory viruses in rural Nepal 2019-10-14 .txt text/plain 4720 215 42 In a prospective longitudinal study utilizing intensive weekly home-based active surveillance to evaluate the household transmission of nine respiratory viruses in rural South Asia, initial infection in young children was associated with the greatest risk of symptomatic respiratory virus household transmission with spread to infants occurring in 45% of transmission events. A higher proportion of initial infection among this group resulted in secondary cases compared to other age groups, including school-age children and mothers, a finding confirmed in our multivariable model of transmission incidence. While a model of Kenya transmission data supports immunizing school-age children to diminish transmission of the virus to infants, our study suggests that in rural South Asia, preschool-age children are more likely to transmit respiratory viruses to other household members [38] . Our study of non-influenza respiratory virus transmission within households in rural Nepal highlights the importance of targeting preschool-age children to prevent the spread of respiratory viral illness. ./cache/cord-327701-1qgaxcqq.txt ./txt/cord-327701-1qgaxcqq.txt