id sid tid token lemma pos cord-292657-gq3965se 1 1 key key JJ cord-292657-gq3965se 2 1 : : : cord-292657-gq3965se 2 2 cord-292657-gq3965se cord-292657-gq3965se NNP cord-292657-gq3965se 2 3 authors author NNS cord-292657-gq3965se 2 4 : : : cord-292657-gq3965se 2 5 Das Das NNP cord-292657-gq3965se 2 6 , , , cord-292657-gq3965se 2 7 Piyanki Piyanki NNP cord-292657-gq3965se 2 8 ; ; : cord-292657-gq3965se 2 9 Choudhuri Choudhuri NNP cord-292657-gq3965se 2 10 , , , cord-292657-gq3965se 2 11 Tathagata Tathagata NNP cord-292657-gq3965se 2 12 title title NN cord-292657-gq3965se 2 13 : : : cord-292657-gq3965se 3 1 Decoding decode VBG cord-292657-gq3965se 3 2 the the DT cord-292657-gq3965se 3 3 global global JJ cord-292657-gq3965se 3 4 outbreak outbreak NN cord-292657-gq3965se 3 5 of of IN cord-292657-gq3965se 3 6 COVID-19 COVID-19 NNP cord-292657-gq3965se 3 7 : : : cord-292657-gq3965se 3 8 the the DT cord-292657-gq3965se 3 9 nature nature NN cord-292657-gq3965se 3 10 is be VBZ cord-292657-gq3965se 3 11 behind behind IN cord-292657-gq3965se 3 12 the the DT cord-292657-gq3965se 3 13 scene scene NN cord-292657-gq3965se 3 14 date date NN cord-292657-gq3965se 3 15 : : : cord-292657-gq3965se 3 16 2020 2020 CD cord-292657-gq3965se 3 17 - - HYPH cord-292657-gq3965se 3 18 06 06 CD cord-292657-gq3965se 3 19 - - SYM cord-292657-gq3965se 3 20 22 22 CD cord-292657-gq3965se 3 21 journal journal NN cord-292657-gq3965se 3 22 : : : cord-292657-gq3965se 4 1 Virusdisease Virusdisease NNP cord-292657-gq3965se 4 2 DOI DOI NNP cord-292657-gq3965se 4 3 : : : cord-292657-gq3965se 5 1 10.1007 10.1007 CD cord-292657-gq3965se 5 2 / / SYM cord-292657-gq3965se 5 3 s13337 s13337 CD cord-292657-gq3965se 5 4 - - HYPH cord-292657-gq3965se 5 5 020 020 CD cord-292657-gq3965se 5 6 - - HYPH cord-292657-gq3965se 5 7 00605-y 00605-y ADD cord-292657-gq3965se 6 1 sha sha NNP cord-292657-gq3965se 6 2 : : : cord-292657-gq3965se 6 3 ba6d0d3851985c876cbaa8355a962819a202986a ba6d0d3851985c876cbaa8355a962819a202986a NNP cord-292657-gq3965se 6 4 doc_id doc_id CD cord-292657-gq3965se 6 5 : : : cord-292657-gq3965se 7 1 292657 292657 CD cord-292657-gq3965se 7 2 cord_uid cord_uid NNS cord-292657-gq3965se 7 3 : : : cord-292657-gq3965se 7 4 gq3965se gq3965se NNP cord-292657-gq3965se 8 1 The the DT cord-292657-gq3965se 8 2 sudden sudden JJ cord-292657-gq3965se 8 3 emergence emergence NN cord-292657-gq3965se 8 4 of of IN cord-292657-gq3965se 8 5 SARS SARS NNP cord-292657-gq3965se 8 6 - - : cord-292657-gq3965se 8 7 CoV-2 CoV-2 NNP cord-292657-gq3965se 8 8 causing cause VBG cord-292657-gq3965se 8 9 the the DT cord-292657-gq3965se 8 10 global global JJ cord-292657-gq3965se 8 11 pandemic pandemic NN cord-292657-gq3965se 8 12 is be VBZ cord-292657-gq3965se 8 13 a a DT cord-292657-gq3965se 8 14 major major JJ cord-292657-gq3965se 8 15 public public JJ cord-292657-gq3965se 8 16 health health NN cord-292657-gq3965se 8 17 concern concern NN cord-292657-gq3965se 8 18 . . . cord-292657-gq3965se 9 1 Though though IN cord-292657-gq3965se 9 2 the the DT cord-292657-gq3965se 9 3 virus virus NN cord-292657-gq3965se 9 4 is be VBZ cord-292657-gq3965se 9 5 considered consider VBN cord-292657-gq3965se 9 6 as as IN cord-292657-gq3965se 9 7 a a DT cord-292657-gq3965se 9 8 novel novel JJ cord-292657-gq3965se 9 9 entity entity NN cord-292657-gq3965se 9 10 , , , cord-292657-gq3965se 9 11 it -PRON- PRP cord-292657-gq3965se 9 12 is be VBZ cord-292657-gq3965se 9 13 not not RB cord-292657-gq3965se 9 14 a a DT cord-292657-gq3965se 9 15 completely completely RB cord-292657-gq3965se 9 16 new new JJ cord-292657-gq3965se 9 17 member member NN cord-292657-gq3965se 9 18 . . . cord-292657-gq3965se 10 1 It -PRON- PRP cord-292657-gq3965se 10 2 is be VBZ cord-292657-gq3965se 10 3 just just RB cord-292657-gq3965se 10 4 a a DT cord-292657-gq3965se 10 5 new new JJ cord-292657-gq3965se 10 6 version version NN cord-292657-gq3965se 10 7 of of IN cord-292657-gq3965se 10 8 previously previously RB cord-292657-gq3965se 10 9 emerged emerge VBN cord-292657-gq3965se 10 10 human human JJ cord-292657-gq3965se 10 11 SARS SARS NNP cord-292657-gq3965se 10 12 corona corona NNP cord-292657-gq3965se 10 13 virus virus NN cord-292657-gq3965se 10 14 . . . cord-292657-gq3965se 11 1 The the DT cord-292657-gq3965se 11 2 rapid rapid JJ cord-292657-gq3965se 11 3 evolving evolve VBG cord-292657-gq3965se 11 4 nature nature NN cord-292657-gq3965se 11 5 by by IN cord-292657-gq3965se 11 6 changing change VBG cord-292657-gq3965se 11 7 host host NN cord-292657-gq3965se 11 8 body body NN cord-292657-gq3965se 11 9 environment environment NN cord-292657-gq3965se 11 10 and and CC cord-292657-gq3965se 11 11 extreme extreme JJ cord-292657-gq3965se 11 12 environmental environmental JJ cord-292657-gq3965se 11 13 stability stability NN cord-292657-gq3965se 11 14 , , , cord-292657-gq3965se 11 15 collectively collectively RB cord-292657-gq3965se 11 16 makes make VBZ cord-292657-gq3965se 11 17 SARS SARS NNP cord-292657-gq3965se 11 18 - - HYPH cord-292657-gq3965se 11 19 CoV-2 CoV-2 NNP cord-292657-gq3965se 11 20 into into IN cord-292657-gq3965se 11 21 an an DT cord-292657-gq3965se 11 22 extremely extremely RB cord-292657-gq3965se 11 23 virulent virulent JJ cord-292657-gq3965se 11 24 genetic genetic JJ cord-292657-gq3965se 11 25 variant variant NN cord-292657-gq3965se 11 26 . . . cord-292657-gq3965se 12 1 The the DT cord-292657-gq3965se 12 2 evolution evolution NN cord-292657-gq3965se 12 3 of of IN cord-292657-gq3965se 12 4 the the DT cord-292657-gq3965se 12 5 virus virus NN cord-292657-gq3965se 12 6 has have VBZ cord-292657-gq3965se 12 7 been be VBN cord-292657-gq3965se 12 8 occurred occur VBN cord-292657-gq3965se 12 9 by by IN cord-292657-gq3965se 12 10 the the DT cord-292657-gq3965se 12 11 continuous continuous JJ cord-292657-gq3965se 12 12 process process NN cord-292657-gq3965se 12 13 of of IN cord-292657-gq3965se 12 14 molecular molecular JJ cord-292657-gq3965se 12 15 genetic genetic JJ cord-292657-gq3965se 12 16 manipulation manipulation NN cord-292657-gq3965se 12 17 , , , cord-292657-gq3965se 12 18 through through IN cord-292657-gq3965se 12 19 mutation mutation NN cord-292657-gq3965se 12 20 , , , cord-292657-gq3965se 12 21 deletion deletion NN cord-292657-gq3965se 12 22 and and CC cord-292657-gq3965se 12 23 genetic genetic JJ cord-292657-gq3965se 12 24 recombinationevents recombinationevent NNS cord-292657-gq3965se 12 25 . . . cord-292657-gq3965se 13 1 Different different JJ cord-292657-gq3965se 13 2 host host NN cord-292657-gq3965se 13 3 body body NN cord-292657-gq3965se 13 4 environment environment NN cord-292657-gq3965se 13 5 acts act VBZ cord-292657-gq3965se 13 6 as as IN cord-292657-gq3965se 13 7 the the DT cord-292657-gq3965se 13 8 supportive supportive JJ cord-292657-gq3965se 13 9 system system NN cord-292657-gq3965se 13 10 for for IN cord-292657-gq3965se 13 11 the the DT cord-292657-gq3965se 13 12 pathogen pathogen NN cord-292657-gq3965se 13 13 which which WDT cord-292657-gq3965se 13 14 creates create VBZ cord-292657-gq3965se 13 15 extreme extreme JJ cord-292657-gq3965se 13 16 selective selective JJ cord-292657-gq3965se 13 17 pressure pressure NN cord-292657-gq3965se 13 18 . . . cord-292657-gq3965se 14 1 By by IN cord-292657-gq3965se 14 2 the the DT cord-292657-gq3965se 14 3 process process NN cord-292657-gq3965se 14 4 of of IN cord-292657-gq3965se 14 5 genetic genetic JJ cord-292657-gq3965se 14 6 evolution evolution NN cord-292657-gq3965se 14 7 the the DT cord-292657-gq3965se 14 8 pathogen pathogen NN cord-292657-gq3965se 14 9 developes develop VBZ cord-292657-gq3965se 14 10 new new JJ cord-292657-gq3965se 14 11 characters character NNS cord-292657-gq3965se 14 12 . . . cord-292657-gq3965se 15 1 Then then RB cord-292657-gq3965se 15 2 the the DT cord-292657-gq3965se 15 3 new new JJ cord-292657-gq3965se 15 4 version version NN cord-292657-gq3965se 15 5 of of IN cord-292657-gq3965se 15 6 the the DT cord-292657-gq3965se 15 7 virus virus NN cord-292657-gq3965se 15 8 has have VBZ cord-292657-gq3965se 15 9 been be VBN cord-292657-gq3965se 15 10 naturally naturally RB cord-292657-gq3965se 15 11 selected select VBN cord-292657-gq3965se 15 12 by by IN cord-292657-gq3965se 15 13 susceptible susceptible JJ cord-292657-gq3965se 15 14 human human JJ cord-292657-gq3965se 15 15 host host NN cord-292657-gq3965se 15 16 and and CC cord-292657-gq3965se 15 17 adapt adapt VB cord-292657-gq3965se 15 18 itself -PRON- PRP cord-292657-gq3965se 15 19 inside inside IN cord-292657-gq3965se 15 20 the the DT cord-292657-gq3965se 15 21 host host NN cord-292657-gq3965se 15 22 body body NN cord-292657-gq3965se 15 23 causing cause VBG cord-292657-gq3965se 15 24 deadly deadly JJ cord-292657-gq3965se 15 25 effect effect NN cord-292657-gq3965se 15 26 . . . cord-292657-gq3965se 16 1 Moreover moreover RB cord-292657-gq3965se 16 2 , , , cord-292657-gq3965se 16 3 extreme extreme JJ cord-292657-gq3965se 16 4 environmental environmental JJ cord-292657-gq3965se 16 5 stability stability NN cord-292657-gq3965se 16 6 helps help VBZ cord-292657-gq3965se 16 7 in in IN cord-292657-gq3965se 16 8 the the DT cord-292657-gq3965se 16 9 process process NN cord-292657-gq3965se 16 10 of of IN cord-292657-gq3965se 16 11 viral viral JJ cord-292657-gq3965se 16 12 survival survival NN cord-292657-gq3965se 16 13 outside outside IN cord-292657-gq3965se 16 14 the the DT cord-292657-gq3965se 16 15 host host NN cord-292657-gq3965se 16 16 and and CC cord-292657-gq3965se 16 17 its -PRON- PRP$ cord-292657-gq3965se 16 18 transmission transmission NN cord-292657-gq3965se 16 19 . . . cord-292657-gq3965se 17 1 Thus thus RB cord-292657-gq3965se 17 2 both both DT cord-292657-gq3965se 17 3 the the DT cord-292657-gq3965se 17 4 host host NN cord-292657-gq3965se 17 5 body body NN cord-292657-gq3965se 17 6 or or CC cord-292657-gq3965se 17 7 internal internal JJ cord-292657-gq3965se 17 8 environment environment NN cord-292657-gq3965se 17 9 and and CC cord-292657-gq3965se 17 10 the the DT cord-292657-gq3965se 17 11 external external JJ cord-292657-gq3965se 17 12 environment environment NN cord-292657-gq3965se 17 13 performs perform VBZ cord-292657-gq3965se 17 14 equally equally RB cord-292657-gq3965se 17 15 as as IN cord-292657-gq3965se 17 16 a a DT cord-292657-gq3965se 17 17 source source NN cord-292657-gq3965se 17 18 , , , cord-292657-gq3965se 17 19 responsible responsible JJ cord-292657-gq3965se 17 20 for for IN cord-292657-gq3965se 17 21 shaping shape VBG cord-292657-gq3965se 17 22 the the DT cord-292657-gq3965se 17 23 genetic genetic JJ cord-292657-gq3965se 17 24 evolution evolution NN cord-292657-gq3965se 17 25 of of IN cord-292657-gq3965se 17 26 the the DT cord-292657-gq3965se 17 27 SARS SARS NNP cord-292657-gq3965se 17 28 - - HYPH cord-292657-gq3965se 17 29 CoV-2 CoV-2 NNP cord-292657-gq3965se 17 30 towards towards IN cord-292657-gq3965se 17 31 theCOVID-19 thecovid-19 CD cord-292657-gq3965se 17 32 disease disease NN cord-292657-gq3965se 17 33 fitness fitness NN cord-292657-gq3965se 17 34 in in IN cord-292657-gq3965se 17 35 nature nature NN cord-292657-gq3965se 17 36 in in IN cord-292657-gq3965se 17 37 a a DT cord-292657-gq3965se 17 38 pandemic pandemic NN cord-292657-gq3965se 17 39 form form NN cord-292657-gq3965se 17 40 . . . cord-292657-gq3965se 18 1 After after IN cord-292657-gq3965se 18 2 so so RB cord-292657-gq3965se 18 3 many many JJ cord-292657-gq3965se 18 4 years year NNS cord-292657-gq3965se 18 5 of of IN cord-292657-gq3965se 18 6 the the DT cord-292657-gq3965se 18 7 discovery discovery NN cord-292657-gq3965se 18 8 of of IN cord-292657-gq3965se 18 9 DNA DNA NNP cord-292657-gq3965se 18 10 / / SYM cord-292657-gq3965se 18 11 RNA RNA NNP cord-292657-gq3965se 18 12 as as IN cord-292657-gq3965se 18 13 the the DT cord-292657-gq3965se 18 14 genetic genetic JJ cord-292657-gq3965se 18 15 base base NN cord-292657-gq3965se 18 16 of of IN cord-292657-gq3965se 18 17 organisms organism NNS cord-292657-gq3965se 18 18 , , , cord-292657-gq3965se 18 19 we -PRON- PRP cord-292657-gq3965se 18 20 are be VBP cord-292657-gq3965se 18 21 not not RB cord-292657-gq3965se 18 22 capable capable JJ cord-292657-gq3965se 18 23 to to TO cord-292657-gq3965se 18 24 fully fully RB cord-292657-gq3965se 18 25 understand understand VB cord-292657-gq3965se 18 26 the the DT cord-292657-gq3965se 18 27 newly newly RB cord-292657-gq3965se 18 28 emerging emerge VBG cord-292657-gq3965se 18 29 diseases disease NNS cord-292657-gq3965se 18 30 based base VBN cord-292657-gq3965se 18 31 on on IN cord-292657-gq3965se 18 32 the the DT cord-292657-gq3965se 18 33 genetic genetic JJ cord-292657-gq3965se 18 34 study study NN cord-292657-gq3965se 18 35 . . . cord-292657-gq3965se 19 1 As as IN cord-292657-gq3965se 19 2 the the DT cord-292657-gq3965se 19 3 human human JJ cord-292657-gq3965se 19 4 population population NN cord-292657-gq3965se 19 5 has have VBZ cord-292657-gq3965se 19 6 been be VBN cord-292657-gq3965se 19 7 evolved evolve VBN cord-292657-gq3965se 19 8 , , , cord-292657-gq3965se 19 9 it -PRON- PRP cord-292657-gq3965se 19 10 is be VBZ cord-292657-gq3965se 19 11 exposed expose VBN cord-292657-gq3965se 19 12 to to IN cord-292657-gq3965se 19 13 new new JJ cord-292657-gq3965se 19 14 environmental environmental JJ cord-292657-gq3965se 19 15 conditions condition NNS cord-292657-gq3965se 19 16 in in IN cord-292657-gq3965se 19 17 terms term NNS cord-292657-gq3965se 19 18 of of IN cord-292657-gq3965se 19 19 migration migration NN cord-292657-gq3965se 19 20 , , , cord-292657-gq3965se 19 21 change change NN cord-292657-gq3965se 19 22 in in IN cord-292657-gq3965se 19 23 food food NN cord-292657-gq3965se 19 24 habits habit NNS cord-292657-gq3965se 19 25 and and CC cord-292657-gq3965se 19 26 lifestyle lifestyle NN cord-292657-gq3965se 19 27 pattern pattern NN cord-292657-gq3965se 19 28 . . . cord-292657-gq3965se 20 1 Parallely parallely RB cord-292657-gq3965se 20 2 they -PRON- PRP cord-292657-gq3965se 20 3 have have VBP cord-292657-gq3965se 20 4 interacted interact VBN cord-292657-gq3965se 20 5 with with IN cord-292657-gq3965se 20 6 wide wide JJ cord-292657-gq3965se 20 7 range range NN cord-292657-gq3965se 20 8 of of IN cord-292657-gq3965se 20 9 new new JJ cord-292657-gq3965se 20 10 micro micro JJ cord-292657-gq3965se 20 11 biome biome NN cord-292657-gq3965se 20 12 . . . cord-292657-gq3965se 21 1 Now now RB cord-292657-gq3965se 21 2 in in IN cord-292657-gq3965se 21 3 this this DT cord-292657-gq3965se 21 4 host host NN cord-292657-gq3965se 21 5 - - HYPH cord-292657-gq3965se 21 6 pathogenic pathogenic JJ cord-292657-gq3965se 21 7 interaction interaction NN cord-292657-gq3965se 21 8 , , , cord-292657-gq3965se 21 9 both both DT cord-292657-gq3965se 21 10 of of IN cord-292657-gq3965se 21 11 them -PRON- PRP cord-292657-gq3965se 21 12 are be VBP cord-292657-gq3965se 21 13 in in IN cord-292657-gq3965se 21 14 a a DT cord-292657-gq3965se 21 15 track track NN cord-292657-gq3965se 21 16 for for IN cord-292657-gq3965se 21 17 winning win VBG cord-292657-gq3965se 21 18 a a DT cord-292657-gq3965se 21 19 race race NN cord-292657-gq3965se 21 20 to to TO cord-292657-gq3965se 21 21 evolve evolve VB cord-292657-gq3965se 21 22 and and CC cord-292657-gq3965se 21 23 establish establish VB cord-292657-gq3965se 21 24 itself -PRON- PRP cord-292657-gq3965se 21 25 by by IN cord-292657-gq3965se 21 26 creating create VBG cord-292657-gq3965se 21 27 immense immense JJ cord-292657-gq3965se 21 28 selective selective JJ cord-292657-gq3965se 21 29 pressure pressure NN cord-292657-gq3965se 21 30 over over IN cord-292657-gq3965se 21 31 each each DT cord-292657-gq3965se 21 32 other other JJ cord-292657-gq3965se 21 33 . . . cord-292657-gq3965se 22 1 Here here RB cord-292657-gq3965se 22 2 comes come VBZ cord-292657-gq3965se 22 3 the the DT cord-292657-gq3965se 22 4 role role NN cord-292657-gq3965se 22 5 of of IN cord-292657-gq3965se 22 6 the the DT cord-292657-gq3965se 22 7 key key JJ cord-292657-gq3965se 22 8 player player NN cord-292657-gq3965se 22 9 , , , cord-292657-gq3965se 22 10 the the DT cord-292657-gq3965se 22 11 nature nature NN cord-292657-gq3965se 22 12 or or CC cord-292657-gq3965se 22 13 environment environment NN cord-292657-gq3965se 22 14 . . . cord-292657-gq3965se 23 1 From from IN cord-292657-gq3965se 23 2 the the DT cord-292657-gq3965se 23 3 origin origin NN cord-292657-gq3965se 23 4 of of IN cord-292657-gq3965se 23 5 life life NN cord-292657-gq3965se 23 6 , , , cord-292657-gq3965se 23 7 the the DT cord-292657-gq3965se 23 8 nature nature NN cord-292657-gq3965se 23 9 ultimately ultimately RB cord-292657-gq3965se 23 10 selects select VBZ cord-292657-gq3965se 23 11 the the DT cord-292657-gq3965se 23 12 prevalence prevalence NN cord-292657-gq3965se 23 13 of of IN cord-292657-gq3965se 23 14 the the DT cord-292657-gq3965se 23 15 genetic genetic JJ cord-292657-gq3965se 23 16 makeup makeup NN cord-292657-gq3965se 23 17 and and CC cord-292657-gq3965se 23 18 decides decide VBZ cord-292657-gq3965se 23 19 the the DT cord-292657-gq3965se 23 20 winner winner NN cord-292657-gq3965se 23 21 beyond beyond IN cord-292657-gq3965se 23 22 the the DT cord-292657-gq3965se 23 23 game game NN cord-292657-gq3965se 23 24 of of IN cord-292657-gq3965se 23 25 neucleotides neucleotide NNS cord-292657-gq3965se 23 26 . . . cord-292657-gq3965se 24 1 The the DT cord-292657-gq3965se 24 2 interplay interplay NN cord-292657-gq3965se 24 3 between between IN cord-292657-gq3965se 24 4 the the DT cord-292657-gq3965se 24 5 environment environment NN cord-292657-gq3965se 24 6 and and CC cord-292657-gq3965se 24 7 the the DT cord-292657-gq3965se 24 8 genetic genetic JJ cord-292657-gq3965se 24 9 material material NN cord-292657-gq3965se 24 10 actually actually RB cord-292657-gq3965se 24 11 creates create VBZ cord-292657-gq3965se 24 12 new new JJ cord-292657-gq3965se 24 13 or or CC cord-292657-gq3965se 24 14 evolved evolve VBN cord-292657-gq3965se 24 15 genetic genetic JJ cord-292657-gq3965se 24 16 variety variety NN cord-292657-gq3965se 24 17 and and CC cord-292657-gq3965se 24 18 selects select VBZ cord-292657-gq3965se 24 19 its -PRON- PRP$ cord-292657-gq3965se 24 20 existence existence NN cord-292657-gq3965se 24 21 both both CC cord-292657-gq3965se 24 22 for for IN cord-292657-gq3965se 24 23 pathogen pathogen NN cord-292657-gq3965se 24 24 and and CC cord-292657-gq3965se 24 25 the the DT cord-292657-gq3965se 24 26 host host NN cord-292657-gq3965se 24 27 and and CC cord-292657-gq3965se 24 28 decides decide VBZ cord-292657-gq3965se 24 29 who who WP cord-292657-gq3965se 24 30 will will MD cord-292657-gq3965se 24 31 dominate dominate VB cord-292657-gq3965se 24 32 in in IN cord-292657-gq3965se 24 33 the the DT cord-292657-gq3965se 24 34 nature nature NN cord-292657-gq3965se 24 35 [ [ -LRB- cord-292657-gq3965se 24 36 2 2 CD cord-292657-gq3965se 24 37 , , , cord-292657-gq3965se 24 38 17 17 CD cord-292657-gq3965se 24 39 ] ] -RRB- cord-292657-gq3965se 24 40 . . . cord-292657-gq3965se 25 1 This this DT cord-292657-gq3965se 25 2 ancient ancient JJ cord-292657-gq3965se 25 3 story story NN cord-292657-gq3965se 25 4 of of IN cord-292657-gq3965se 25 5 nature nature NN cord-292657-gq3965se 25 6 's 's POS cord-292657-gq3965se 25 7 selection selection NN cord-292657-gq3965se 25 8 rule rule NN cord-292657-gq3965se 25 9 has have VBZ cord-292657-gq3965se 25 10 been be VBN cord-292657-gq3965se 25 11 observed observe VBN cord-292657-gq3965se 25 12 for for IN cord-292657-gq3965se 25 13 the the DT cord-292657-gq3965se 25 14 development development NN cord-292657-gq3965se 25 15 of of IN cord-292657-gq3965se 25 16 novel novel JJ cord-292657-gq3965se 25 17 diseases disease NNS cord-292657-gq3965se 25 18 like like IN cord-292657-gq3965se 25 19 , , , cord-292657-gq3965se 25 20 small small JJ cord-292657-gq3965se 25 21 pox pox NN cord-292657-gq3965se 25 22 , , , cord-292657-gq3965se 25 23 cholera cholera NN cord-292657-gq3965se 25 24 , , , cord-292657-gq3965se 25 25 tuberculosis tuberculosis NN cord-292657-gq3965se 25 26 and and CC cord-292657-gq3965se 25 27 in in IN cord-292657-gq3965se 25 28 recent recent JJ cord-292657-gq3965se 25 29 past past NN cord-292657-gq3965se 25 30 like like UH cord-292657-gq3965se 25 31 , , , cord-292657-gq3965se 25 32 AIDS AIDS NNP cord-292657-gq3965se 25 33 , , , cord-292657-gq3965se 25 34 different different JJ cord-292657-gq3965se 25 35 flus flu NNS cord-292657-gq3965se 25 36 and and CC cord-292657-gq3965se 25 37 the the DT cord-292657-gq3965se 25 38 most most RBS cord-292657-gq3965se 25 39 related related JJ cord-292657-gq3965se 25 40 newly newly RB cord-292657-gq3965se 25 41 emerging emerge VBG cord-292657-gq3965se 25 42 SARS SARS NNP cord-292657-gq3965se 25 43 ( ( -LRB- cord-292657-gq3965se 25 44 Severe severe JJ cord-292657-gq3965se 25 45 acute acute JJ cord-292657-gq3965se 25 46 respiratory respiratory JJ cord-292657-gq3965se 25 47 syndrome syndrome NN cord-292657-gq3965se 25 48 ) ) -RRB- cord-292657-gq3965se 25 49 and and CC cord-292657-gq3965se 25 50 MERS MERS NNP cord-292657-gq3965se 25 51 ( ( -LRB- cord-292657-gq3965se 25 52 Middle Middle NNP cord-292657-gq3965se 25 53 East East NNP cord-292657-gq3965se 25 54 respiratory respiratory JJ cord-292657-gq3965se 25 55 syndrome syndrome NN cord-292657-gq3965se 25 56 ) ) -RRB- cord-292657-gq3965se 25 57 outbreak outbreak NN cord-292657-gq3965se 25 58 [ [ -LRB- cord-292657-gq3965se 25 59 31 31 CD cord-292657-gq3965se 25 60 ] ] -RRB- cord-292657-gq3965se 25 61 . . . cord-292657-gq3965se 26 1 In in IN cord-292657-gq3965se 26 2 the the DT cord-292657-gq3965se 26 3 current current JJ cord-292657-gq3965se 26 4 global global JJ cord-292657-gq3965se 26 5 COVID-19 covid-19 CD cord-292657-gq3965se 26 6 outbreak outbreak NN cord-292657-gq3965se 26 7 , , , cord-292657-gq3965se 26 8 which which WDT cord-292657-gq3965se 26 9 is be VBZ cord-292657-gq3965se 26 10 the the DT cord-292657-gq3965se 26 11 major major JJ cord-292657-gq3965se 26 12 health health NN cord-292657-gq3965se 26 13 concern concern NN cord-292657-gq3965se 26 14 in in IN cord-292657-gq3965se 26 15 the the DT cord-292657-gq3965se 26 16 world world NN cord-292657-gq3965se 26 17 , , , cord-292657-gq3965se 26 18 it -PRON- PRP cord-292657-gq3965se 26 19 is be VBZ cord-292657-gq3965se 26 20 very very RB cord-292657-gq3965se 26 21 important important JJ cord-292657-gq3965se 26 22 to to TO cord-292657-gq3965se 26 23 understand understand VB cord-292657-gq3965se 26 24 how how WRB cord-292657-gq3965se 26 25 this this DT cord-292657-gq3965se 26 26 novel novel JJ cord-292657-gq3965se 26 27 entity entity NN cord-292657-gq3965se 26 28 suddenly suddenly RB cord-292657-gq3965se 26 29 emerged emerge VBD cord-292657-gq3965se 26 30 and and CC cord-292657-gq3965se 26 31 capable capable JJ cord-292657-gq3965se 26 32 enough enough RB cord-292657-gq3965se 26 33 to to TO cord-292657-gq3965se 26 34 create create VB cord-292657-gq3965se 26 35 a a DT cord-292657-gq3965se 26 36 global global JJ cord-292657-gq3965se 26 37 pandemic pandemic NN cord-292657-gq3965se 26 38 with with IN cord-292657-gq3965se 26 39 its -PRON- PRP$ cord-292657-gq3965se 26 40 fetal fetal JJ cord-292657-gq3965se 26 41 form form NN cord-292657-gq3965se 26 42 . . . cord-292657-gq3965se 27 1 In in IN cord-292657-gq3965se 27 2 this this DT cord-292657-gq3965se 27 3 regard regard NN cord-292657-gq3965se 27 4 prevention prevention NN cord-292657-gq3965se 27 5 in in IN cord-292657-gq3965se 27 6 form form NN cord-292657-gq3965se 27 7 of of IN cord-292657-gq3965se 27 8 vaccination vaccination NN cord-292657-gq3965se 27 9 is be VBZ cord-292657-gq3965se 27 10 the the DT cord-292657-gq3965se 27 11 only only JJ cord-292657-gq3965se 27 12 way way NN cord-292657-gq3965se 27 13 to to TO cord-292657-gq3965se 27 14 combat combat VB cord-292657-gq3965se 27 15 the the DT cord-292657-gq3965se 27 16 disease disease NN cord-292657-gq3965se 27 17 and and CC cord-292657-gq3965se 27 18 genome genome NN cord-292657-gq3965se 27 19 study study NN cord-292657-gq3965se 27 20 is be VBZ cord-292657-gq3965se 27 21 the the DT cord-292657-gq3965se 27 22 basic basic JJ cord-292657-gq3965se 27 23 thing thing NN cord-292657-gq3965se 27 24 . . . cord-292657-gq3965se 28 1 But but CC cord-292657-gq3965se 28 2 beyond beyond IN cord-292657-gq3965se 28 3 this this DT cord-292657-gq3965se 28 4 , , , cord-292657-gq3965se 28 5 the the DT cord-292657-gq3965se 28 6 effect effect NN cord-292657-gq3965se 28 7 of of IN cord-292657-gq3965se 28 8 nature nature NN cord-292657-gq3965se 28 9 over over IN cord-292657-gq3965se 28 10 it -PRON- PRP cord-292657-gq3965se 28 11 needs need VBZ cord-292657-gq3965se 28 12 to to TO cord-292657-gq3965se 28 13 be be VB cord-292657-gq3965se 28 14 understood understand VBN cord-292657-gq3965se 28 15 to to TO cord-292657-gq3965se 28 16 evade evade VB cord-292657-gq3965se 28 17 the the DT cord-292657-gq3965se 28 18 origin origin NN cord-292657-gq3965se 28 19 and and CC cord-292657-gq3965se 28 20 evolution evolution NN cord-292657-gq3965se 28 21 of of IN cord-292657-gq3965se 28 22 the the DT cord-292657-gq3965se 28 23 new new JJ cord-292657-gq3965se 28 24 genetic genetic JJ cord-292657-gq3965se 28 25 character character NN cord-292657-gq3965se 28 26 and and CC cord-292657-gq3965se 28 27 its -PRON- PRP$ cord-292657-gq3965se 28 28 virulent virulent JJ cord-292657-gq3965se 28 29 establishment establishment NN cord-292657-gq3965se 28 30 in in IN cord-292657-gq3965se 28 31 nature nature NN cord-292657-gq3965se 28 32 by by IN cord-292657-gq3965se 28 33 population population NN cord-292657-gq3965se 28 34 distribution distribution NN cord-292657-gq3965se 28 35 . . . cord-292657-gq3965se 29 1 It -PRON- PRP cord-292657-gq3965se 29 2 has have VBZ cord-292657-gq3965se 29 3 been be VBN cord-292657-gq3965se 29 4 observed observe VBN cord-292657-gq3965se 29 5 that that IN cord-292657-gq3965se 29 6 40 40 CD cord-292657-gq3965se 29 7 % % NN cord-292657-gq3965se 29 8 of of IN cord-292657-gq3965se 29 9 the the DT cord-292657-gq3965se 29 10 new new JJ cord-292657-gq3965se 29 11 emerging emerge VBG cord-292657-gq3965se 29 12 diseases disease NNS cord-292657-gq3965se 29 13 is be VBZ cord-292657-gq3965se 29 14 caused cause VBN cord-292657-gq3965se 29 15 by by IN cord-292657-gq3965se 29 16 virus virus NN cord-292657-gq3965se 29 17 , , , cord-292657-gq3965se 29 18 and and CC cord-292657-gq3965se 29 19 RNA RNA NNP cord-292657-gq3965se 29 20 virus virus NN cord-292657-gq3965se 29 21 are be VBP cord-292657-gq3965se 29 22 too too RB cord-292657-gq3965se 29 23 much much JJ cord-292657-gq3965se 29 24 progressive progressive JJ cord-292657-gq3965se 29 25 in in IN cord-292657-gq3965se 29 26 this this DT cord-292657-gq3965se 29 27 case case NN cord-292657-gq3965se 29 28 . . . cord-292657-gq3965se 30 1 Thus thus RB cord-292657-gq3965se 30 2 how how WRB cord-292657-gq3965se 30 3 these these DT cord-292657-gq3965se 30 4 RNA RNA NNP cord-292657-gq3965se 30 5 based base VBN cord-292657-gq3965se 30 6 fetal fetal JJ cord-292657-gq3965se 30 7 pathogen pathogen NN cord-292657-gq3965se 30 8 with with IN cord-292657-gq3965se 30 9 their -PRON- PRP$ cord-292657-gq3965se 30 10 upgraded upgraded JJ cord-292657-gq3965se 30 11 genetic genetic JJ cord-292657-gq3965se 30 12 setup setup NN cord-292657-gq3965se 30 13 has have VBZ cord-292657-gq3965se 30 14 been be VBN cord-292657-gq3965se 30 15 originated originate VBN cord-292657-gq3965se 30 16 and and CC cord-292657-gq3965se 30 17 selected select VBN cord-292657-gq3965se 30 18 by by IN cord-292657-gq3965se 30 19 nature nature NN cord-292657-gq3965se 30 20 with with IN cord-292657-gq3965se 30 21 its -PRON- PRP$ cord-292657-gq3965se 30 22 disease disease NN cord-292657-gq3965se 30 23 outcome outcome NN cord-292657-gq3965se 30 24 must must MD cord-292657-gq3965se 30 25 be be VB cord-292657-gq3965se 30 26 analyzed analyze VBN cord-292657-gq3965se 30 27 well well RB cord-292657-gq3965se 30 28 [ [ -LRB- cord-292657-gq3965se 30 29 5 5 CD cord-292657-gq3965se 30 30 , , , cord-292657-gq3965se 30 31 31 31 CD cord-292657-gq3965se 30 32 ] ] -RRB- cord-292657-gq3965se 30 33 . . . cord-292657-gq3965se 31 1 COVID-19 COVID-19 NNP cord-292657-gq3965se 31 2 is be VBZ cord-292657-gq3965se 31 3 a a DT cord-292657-gq3965se 31 4 viral viral JJ cord-292657-gq3965se 31 5 disease disease NN cord-292657-gq3965se 31 6 caused cause VBN cord-292657-gq3965se 31 7 by by IN cord-292657-gq3965se 31 8 human human JJ cord-292657-gq3965se 31 9 RNA RNA NNP cord-292657-gq3965se 31 10 virus virus NN cord-292657-gq3965se 31 11 SARS SARS NNP cord-292657-gq3965se 31 12 - - HYPH cord-292657-gq3965se 31 13 CoV-2 CoV-2 NNP cord-292657-gq3965se 31 14 . . . cord-292657-gq3965se 32 1 In in IN cord-292657-gq3965se 32 2 this this DT cord-292657-gq3965se 32 3 review review NN cord-292657-gq3965se 32 4 we -PRON- PRP cord-292657-gq3965se 32 5 will will MD cord-292657-gq3965se 32 6 focus focus VB cord-292657-gq3965se 32 7 on on IN cord-292657-gq3965se 32 8 how how WRB cord-292657-gq3965se 32 9 the the DT cord-292657-gq3965se 32 10 viral viral JJ cord-292657-gq3965se 32 11 pathogen pathogen NN cord-292657-gq3965se 32 12 is be VBZ cord-292657-gq3965se 32 13 evolved evolve VBN cord-292657-gq3965se 32 14 and and CC cord-292657-gq3965se 32 15 potent potent JJ cord-292657-gq3965se 32 16 enough enough RB cord-292657-gq3965se 32 17 to to TO cord-292657-gq3965se 32 18 cause cause VB cord-292657-gq3965se 32 19 infection infection NN cord-292657-gq3965se 32 20 at at IN cord-292657-gq3965se 32 21 pandemic pandemic NN cord-292657-gq3965se 32 22 level level NN cord-292657-gq3965se 32 23 from from IN cord-292657-gq3965se 32 24 nature nature NN cord-292657-gq3965se 32 25 's 's POS cord-292657-gq3965se 32 26 point point NN cord-292657-gq3965se 32 27 of of IN cord-292657-gq3965se 32 28 view view NN cord-292657-gq3965se 32 29 . . . cord-292657-gq3965se 33 1 In in IN cord-292657-gq3965se 33 2 case case NN cord-292657-gq3965se 33 3 of of IN cord-292657-gq3965se 33 4 infectious infectious JJ cord-292657-gq3965se 33 5 disease disease NN cord-292657-gq3965se 33 6 , , , cord-292657-gq3965se 33 7 the the DT cord-292657-gq3965se 33 8 host host NN cord-292657-gq3965se 33 9 - - HYPH cord-292657-gq3965se 33 10 pathogen pathogen NN cord-292657-gq3965se 33 11 interaction interaction NN cord-292657-gq3965se 33 12 must must MD cord-292657-gq3965se 33 13 be be VB cord-292657-gq3965se 33 14 understood understand VBN cord-292657-gq3965se 33 15 where where WRB cord-292657-gq3965se 33 16 the the DT cord-292657-gq3965se 33 17 host host NN cord-292657-gq3965se 33 18 environment environment NN cord-292657-gq3965se 33 19 attributes attribute VBZ cord-292657-gq3965se 33 20 a a DT cord-292657-gq3965se 33 21 major major JJ cord-292657-gq3965se 33 22 role role NN cord-292657-gq3965se 33 23 in in IN cord-292657-gq3965se 33 24 the the DT cord-292657-gq3965se 33 25 establishment establishment NN cord-292657-gq3965se 33 26 of of IN cord-292657-gq3965se 33 27 disease disease NN cord-292657-gq3965se 33 28 . . . cord-292657-gq3965se 34 1 In in IN cord-292657-gq3965se 34 2 case case NN cord-292657-gq3965se 34 3 of of IN cord-292657-gq3965se 34 4 any any DT cord-292657-gq3965se 34 5 pathogenic pathogenic JJ cord-292657-gq3965se 34 6 disease disease NN cord-292657-gq3965se 34 7 outcome outcome NN cord-292657-gq3965se 34 8 both both CC cord-292657-gq3965se 34 9 the the DT cord-292657-gq3965se 34 10 host host NN cord-292657-gq3965se 34 11 and and CC cord-292657-gq3965se 34 12 the the DT cord-292657-gq3965se 34 13 pathogen pathogen NN cord-292657-gq3965se 34 14 struggles struggle VBZ cord-292657-gq3965se 34 15 with with IN cord-292657-gq3965se 34 16 each each DT cord-292657-gq3965se 34 17 other other JJ cord-292657-gq3965se 34 18 with with IN cord-292657-gq3965se 34 19 their -PRON- PRP$ cord-292657-gq3965se 34 20 unique unique JJ cord-292657-gq3965se 34 21 genetic genetic JJ cord-292657-gq3965se 34 22 setup setup NN cord-292657-gq3965se 34 23 but but CC cord-292657-gq3965se 34 24 the the DT cord-292657-gq3965se 34 25 gene gene NN cord-292657-gq3965se 34 26 function function NN cord-292657-gq3965se 34 27 is be VBZ cord-292657-gq3965se 34 28 not not RB cord-292657-gq3965se 34 29 the the DT cord-292657-gq3965se 34 30 only only JJ cord-292657-gq3965se 34 31 factor factor NN cord-292657-gq3965se 34 32 for for IN cord-292657-gq3965se 34 33 disease disease NN cord-292657-gq3965se 34 34 establishment establishment NN cord-292657-gq3965se 34 35 or or CC cord-292657-gq3965se 34 36 the the DT cord-292657-gq3965se 34 37 healthy healthy JJ cord-292657-gq3965se 34 38 body body NN cord-292657-gq3965se 34 39 maintenance maintenance NN cord-292657-gq3965se 34 40 . . . cord-292657-gq3965se 35 1 The the DT cord-292657-gq3965se 35 2 environmental environmental JJ cord-292657-gq3965se 35 3 conditions condition NNS cord-292657-gq3965se 35 4 during during IN cord-292657-gq3965se 35 5 this this DT cord-292657-gq3965se 35 6 struggle struggle NN cord-292657-gq3965se 35 7 play play VBP cord-292657-gq3965se 35 8 influential influential JJ cord-292657-gq3965se 35 9 role role NN cord-292657-gq3965se 35 10 in in IN cord-292657-gq3965se 35 11 the the DT cord-292657-gq3965se 35 12 action action NN cord-292657-gq3965se 35 13 of of IN cord-292657-gq3965se 35 14 genome genome NN cord-292657-gq3965se 35 15 , , , cord-292657-gq3965se 35 16 more more RBR cord-292657-gq3965se 35 17 specifically specifically RB cord-292657-gq3965se 35 18 , , , cord-292657-gq3965se 35 19 collective collective JJ cord-292657-gq3965se 35 20 action action NN cord-292657-gq3965se 35 21 of of IN cord-292657-gq3965se 35 22 environment environment NN cord-292657-gq3965se 35 23 and and CC cord-292657-gq3965se 35 24 genetic genetic JJ cord-292657-gq3965se 35 25 mutation mutation NN cord-292657-gq3965se 35 26 affects affect VBZ cord-292657-gq3965se 35 27 the the DT cord-292657-gq3965se 35 28 regulation regulation NN cord-292657-gq3965se 35 29 and and CC cord-292657-gq3965se 35 30 function function NN cord-292657-gq3965se 35 31 of of IN cord-292657-gq3965se 35 32 genes gene NNS cord-292657-gq3965se 35 33 [ [ -LRB- cord-292657-gq3965se 35 34 5 5 CD cord-292657-gq3965se 35 35 ] ] -RRB- cord-292657-gq3965se 35 36 . . . cord-292657-gq3965se 36 1 Moreover moreover RB cord-292657-gq3965se 36 2 when when WRB cord-292657-gq3965se 36 3 we -PRON- PRP cord-292657-gq3965se 36 4 consider consider VBP cord-292657-gq3965se 36 5 a a DT cord-292657-gq3965se 36 6 virus virus NN cord-292657-gq3965se 36 7 , , , cord-292657-gq3965se 36 8 it -PRON- PRP cord-292657-gq3965se 36 9 needs need VBZ cord-292657-gq3965se 36 10 a a DT cord-292657-gq3965se 36 11 living live VBG cord-292657-gq3965se 36 12 body body NN cord-292657-gq3965se 36 13 to to IN cord-292657-gq3965se 36 14 functionally functionally RB cord-292657-gq3965se 36 15 active active JJ cord-292657-gq3965se 36 16 and and CC cord-292657-gq3965se 36 17 thus thus RB cord-292657-gq3965se 36 18 we -PRON- PRP cord-292657-gq3965se 36 19 can can MD cord-292657-gq3965se 36 20 say say VB cord-292657-gq3965se 36 21 that that IN cord-292657-gq3965se 36 22 , , , cord-292657-gq3965se 36 23 the the DT cord-292657-gq3965se 36 24 environment environment NN cord-292657-gq3965se 36 25 for for IN cord-292657-gq3965se 36 26 the the DT cord-292657-gq3965se 36 27 virus virus NN cord-292657-gq3965se 36 28 to to TO cord-292657-gq3965se 36 29 work work VB cord-292657-gq3965se 36 30 is be VBZ cord-292657-gq3965se 36 31 its -PRON- PRP$ cord-292657-gq3965se 36 32 host host NN cord-292657-gq3965se 36 33 body body NN cord-292657-gq3965se 36 34 environment environment NN cord-292657-gq3965se 36 35 . . . cord-292657-gq3965se 37 1 On on IN cord-292657-gq3965se 37 2 the the DT cord-292657-gq3965se 37 3 other other JJ cord-292657-gq3965se 37 4 hand hand NN cord-292657-gq3965se 37 5 the the DT cord-292657-gq3965se 37 6 host host NN cord-292657-gq3965se 37 7 body body NN cord-292657-gq3965se 37 8 where where WRB cord-292657-gq3965se 37 9 the the DT cord-292657-gq3965se 37 10 virus virus NN cord-292657-gq3965se 37 11 survives survive VBZ cord-292657-gq3965se 37 12 also also RB cord-292657-gq3965se 37 13 needs need VBZ cord-292657-gq3965se 37 14 the the DT cord-292657-gq3965se 37 15 external external JJ cord-292657-gq3965se 37 16 environment environment NN cord-292657-gq3965se 37 17 as as IN cord-292657-gq3965se 37 18 its -PRON- PRP$ cord-292657-gq3965se 37 19 survival survival NN cord-292657-gq3965se 37 20 resource resource NN cord-292657-gq3965se 37 21 during during IN cord-292657-gq3965se 37 22 transmission transmission NN cord-292657-gq3965se 37 23 . . . cord-292657-gq3965se 38 1 Now now RB cord-292657-gq3965se 38 2 in in IN cord-292657-gq3965se 38 3 the the DT cord-292657-gq3965se 38 4 following following JJ cord-292657-gq3965se 38 5 discussion discussion NN cord-292657-gq3965se 38 6 we -PRON- PRP cord-292657-gq3965se 38 7 will will MD cord-292657-gq3965se 38 8 try try VB cord-292657-gq3965se 38 9 to to TO cord-292657-gq3965se 38 10 understand understand VB cord-292657-gq3965se 38 11 how how WRB cord-292657-gq3965se 38 12 these these DT cord-292657-gq3965se 38 13 two two CD cord-292657-gq3965se 38 14 kinds kind NNS cord-292657-gq3965se 38 15 of of IN cord-292657-gq3965se 38 16 environment environment NN cord-292657-gq3965se 38 17 interplay interplay JJ cord-292657-gq3965se 38 18 in in IN cord-292657-gq3965se 38 19 the the DT cord-292657-gq3965se 38 20 development development NN cord-292657-gq3965se 38 21 of of IN cord-292657-gq3965se 38 22 the the DT cord-292657-gq3965se 38 23 virus virus NN cord-292657-gq3965se 38 24 , , , cord-292657-gq3965se 38 25 causing cause VBG cord-292657-gq3965se 38 26 current current JJ cord-292657-gq3965se 38 27 COVID-19 covid-19 CD cord-292657-gq3965se 38 28 outbreak outbreak NN cord-292657-gq3965se 38 29 . . . cord-292657-gq3965se 39 1 Nature nature NN cord-292657-gq3965se 39 2 is be VBZ cord-292657-gq3965se 39 3 the the DT cord-292657-gq3965se 39 4 key key JJ cord-292657-gq3965se 39 5 player player NN cord-292657-gq3965se 39 6 of of IN cord-292657-gq3965se 39 7 origin origin NN cord-292657-gq3965se 39 8 , , , cord-292657-gq3965se 39 9 evolution evolution NN cord-292657-gq3965se 39 10 and and CC cord-292657-gq3965se 39 11 pathogenicity pathogenicity NN cord-292657-gq3965se 39 12 of of IN cord-292657-gq3965se 39 13 the the DT cord-292657-gq3965se 39 14 virus virus NN cord-292657-gq3965se 39 15 To to TO cord-292657-gq3965se 39 16 understand understand VB cord-292657-gq3965se 39 17 the the DT cord-292657-gq3965se 39 18 root root NN cord-292657-gq3965se 39 19 of of IN cord-292657-gq3965se 39 20 the the DT cord-292657-gq3965se 39 21 novel novel JJ cord-292657-gq3965se 39 22 viral viral JJ cord-292657-gq3965se 39 23 pathogen pathogen NN cord-292657-gq3965se 39 24 and and CC cord-292657-gq3965se 39 25 role role NN cord-292657-gq3965se 39 26 of of IN cord-292657-gq3965se 39 27 environment environment NN cord-292657-gq3965se 39 28 for for IN cord-292657-gq3965se 39 29 its -PRON- PRP$ cord-292657-gq3965se 39 30 development development NN cord-292657-gq3965se 39 31 , , , cord-292657-gq3965se 39 32 we -PRON- PRP cord-292657-gq3965se 39 33 need need VBP cord-292657-gq3965se 39 34 to to TO cord-292657-gq3965se 39 35 explain explain VB cord-292657-gq3965se 39 36 it -PRON- PRP cord-292657-gq3965se 39 37 with with IN cord-292657-gq3965se 39 38 the the DT cord-292657-gq3965se 39 39 molecular molecular JJ cord-292657-gq3965se 39 40 basis basis NN cord-292657-gq3965se 39 41 of of IN cord-292657-gq3965se 39 42 Darwin Darwin NNP cord-292657-gq3965se 39 43 's 's POS cord-292657-gq3965se 39 44 theory theory NN cord-292657-gq3965se 39 45 of of IN cord-292657-gq3965se 39 46 evolution evolution NN cord-292657-gq3965se 39 47 and and CC cord-292657-gq3965se 39 48 natural natural JJ cord-292657-gq3965se 39 49 selection selection NN cord-292657-gq3965se 39 50 by by IN cord-292657-gq3965se 39 51 the the DT cord-292657-gq3965se 39 52 continuous continuous JJ cord-292657-gq3965se 39 53 process process NN cord-292657-gq3965se 39 54 of of IN cord-292657-gq3965se 39 55 genetic genetic JJ cord-292657-gq3965se 39 56 permutation permutation NN cord-292657-gq3965se 39 57 and and CC cord-292657-gq3965se 39 58 combination combination NN cord-292657-gq3965se 39 59 . . . cord-292657-gq3965se 40 1 SARS SARS NNP cord-292657-gq3965se 40 2 - - HYPH cord-292657-gq3965se 40 3 CoV-2 CoV-2 NNP cord-292657-gq3965se 40 4 is be VBZ cord-292657-gq3965se 40 5 associated associate VBN cord-292657-gq3965se 40 6 with with IN cord-292657-gq3965se 40 7 respiratory respiratory JJ cord-292657-gq3965se 40 8 syndromes syndrome NNS cord-292657-gq3965se 40 9 showing show VBG cord-292657-gq3965se 40 10 flue flue NN cord-292657-gq3965se 40 11 like like IN cord-292657-gq3965se 40 12 symptoms symptom NNS cord-292657-gq3965se 40 13 . . . cord-292657-gq3965se 41 1 If if IN cord-292657-gq3965se 41 2 we -PRON- PRP cord-292657-gq3965se 41 3 recall recall VBP cord-292657-gq3965se 41 4 the the DT cord-292657-gq3965se 41 5 emergence emergence NN cord-292657-gq3965se 41 6 of of IN cord-292657-gq3965se 41 7 different different JJ cord-292657-gq3965se 41 8 other other JJ cord-292657-gq3965se 41 9 deadly deadly JJ cord-292657-gq3965se 41 10 viral viral JJ cord-292657-gq3965se 41 11 flue flue NN cord-292657-gq3965se 41 12 pandemics pandemic NNS cord-292657-gq3965se 41 13 , , , cord-292657-gq3965se 41 14 specifically specifically RB cord-292657-gq3965se 41 15 the the DT cord-292657-gq3965se 41 16 SARS SARS NNP cord-292657-gq3965se 41 17 and and CC cord-292657-gq3965se 41 18 MERS MERS NNPS cord-292657-gq3965se 41 19 in in IN cord-292657-gq3965se 41 20 past past NN cord-292657-gq3965se 41 21 , , , cord-292657-gq3965se 41 22 all all DT cord-292657-gq3965se 41 23 of of IN cord-292657-gq3965se 41 24 them -PRON- PRP cord-292657-gq3965se 41 25 are be VBP cord-292657-gq3965se 41 26 of of IN cord-292657-gq3965se 41 27 similar similar JJ cord-292657-gq3965se 41 28 kind kind NN cord-292657-gq3965se 41 29 with with IN cord-292657-gq3965se 41 30 different different JJ cord-292657-gq3965se 41 31 version version NN cord-292657-gq3965se 41 32 and and CC cord-292657-gq3965se 41 33 originated originate VBN cord-292657-gq3965se 41 34 by by IN cord-292657-gq3965se 41 35 species species NN cord-292657-gq3965se 41 36 spill spill VBP cord-292657-gq3965se 41 37 over over IN cord-292657-gq3965se 41 38 and and CC cord-292657-gq3965se 41 39 zoonotic zoonotic JJ cord-292657-gq3965se 41 40 transfer transfer NN cord-292657-gq3965se 41 41 , , , cord-292657-gq3965se 41 42 which which WDT cord-292657-gq3965se 41 43 is be VBZ cord-292657-gq3965se 41 44 occurred occur VBN cord-292657-gq3965se 41 45 once once RB cord-292657-gq3965se 41 46 in in IN cord-292657-gq3965se 41 47 a a DT cord-292657-gq3965se 41 48 while while NN cord-292657-gq3965se 41 49 over over IN cord-292657-gq3965se 41 50 a a DT cord-292657-gq3965se 41 51 period period NN cord-292657-gq3965se 41 52 . . . cord-292657-gq3965se 42 1 All all DT cord-292657-gq3965se 42 2 of of IN cord-292657-gq3965se 42 3 these these DT cord-292657-gq3965se 42 4 evidences evidence NNS cord-292657-gq3965se 42 5 indicate indicate VBP cord-292657-gq3965se 42 6 towards towards IN cord-292657-gq3965se 42 7 the the DT cord-292657-gq3965se 42 8 origin origin NN cord-292657-gq3965se 42 9 of of IN cord-292657-gq3965se 42 10 the the DT cord-292657-gq3965se 42 11 pathogens pathogen NNS cord-292657-gq3965se 42 12 from from IN cord-292657-gq3965se 42 13 a a DT cord-292657-gq3965se 42 14 common common JJ cord-292657-gq3965se 42 15 ancestral ancestral JJ cord-292657-gq3965se 42 16 form form NN cord-292657-gq3965se 42 17 which which WDT cord-292657-gq3965se 42 18 needs need VBZ cord-292657-gq3965se 42 19 to to TO cord-292657-gq3965se 42 20 be be VB cord-292657-gq3965se 42 21 investigated investigate VBN cord-292657-gq3965se 42 22 . . . cord-292657-gq3965se 43 1 The the DT cord-292657-gq3965se 43 2 probable probable JJ cord-292657-gq3965se 43 3 line line NN cord-292657-gq3965se 43 4 of of IN cord-292657-gq3965se 43 5 development development NN cord-292657-gq3965se 43 6 for for IN cord-292657-gq3965se 43 7 such such JJ cord-292657-gq3965se 43 8 pandemic pandemic NN cord-292657-gq3965se 43 9 outcomes outcome NNS cord-292657-gq3965se 43 10 happened happen VBN cord-292657-gq3965se 43 11 by by IN cord-292657-gq3965se 43 12 continuous continuous JJ cord-292657-gq3965se 43 13 evolutionary evolutionary JJ cord-292657-gq3965se 43 14 procedure procedure NN cord-292657-gq3965se 43 15 within within IN cord-292657-gq3965se 43 16 different different JJ cord-292657-gq3965se 43 17 species specie NNS cord-292657-gq3965se 43 18 or or CC cord-292657-gq3965se 43 19 host host NN cord-292657-gq3965se 43 20 environment environment NN cord-292657-gq3965se 43 21 exposure exposure NN cord-292657-gq3965se 43 22 , , , cord-292657-gq3965se 43 23 by by IN cord-292657-gq3965se 43 24 mutation mutation NN cord-292657-gq3965se 43 25 during during IN cord-292657-gq3965se 43 26 replication replication NN cord-292657-gq3965se 43 27 or or CC cord-292657-gq3965se 43 28 genetic genetic JJ cord-292657-gq3965se 43 29 recombination recombination NN cord-292657-gq3965se 43 30 between between IN cord-292657-gq3965se 43 31 two two CD cord-292657-gq3965se 43 32 different different JJ cord-292657-gq3965se 43 33 viral viral JJ cord-292657-gq3965se 43 34 species specie NNS cord-292657-gq3965se 43 35 and and CC cord-292657-gq3965se 43 36 ultimate ultimate JJ cord-292657-gq3965se 43 37 adaptation adaptation NN cord-292657-gq3965se 43 38 to to IN cord-292657-gq3965se 43 39 a a DT cord-292657-gq3965se 43 40 susceptible susceptible JJ cord-292657-gq3965se 43 41 host host NN cord-292657-gq3965se 43 42 by by IN cord-292657-gq3965se 43 43 natural natural JJ cord-292657-gq3965se 43 44 selection selection NN cord-292657-gq3965se 43 45 of of IN cord-292657-gq3965se 43 46 the the DT cord-292657-gq3965se 43 47 new new JJ cord-292657-gq3965se 43 48 version version NN cord-292657-gq3965se 43 49 of of IN cord-292657-gq3965se 43 50 the the DT cord-292657-gq3965se 43 51 viable viable JJ cord-292657-gq3965se 43 52 pathogen pathogen NN cord-292657-gq3965se 43 53 resulting result VBG cord-292657-gq3965se 43 54 infection infection NN cord-292657-gq3965se 43 55 [ [ -LRB- cord-292657-gq3965se 43 56 7 7 CD cord-292657-gq3965se 43 57 , , , cord-292657-gq3965se 43 58 8 8 CD cord-292657-gq3965se 43 59 ] ] -RRB- cord-292657-gq3965se 43 60 . . . cord-292657-gq3965se 44 1 In in IN cord-292657-gq3965se 44 2 case case NN cord-292657-gq3965se 44 3 of of IN cord-292657-gq3965se 44 4 these these DT cord-292657-gq3965se 44 5 pandemics pandemic NNS cord-292657-gq3965se 44 6 , , , cord-292657-gq3965se 44 7 beyond beyond IN cord-292657-gq3965se 44 8 the the DT cord-292657-gq3965se 44 9 genetic genetic JJ cord-292657-gq3965se 44 10 mechanisms mechanism NNS cord-292657-gq3965se 44 11 , , , cord-292657-gq3965se 44 12 varied varied JJ cord-292657-gq3965se 44 13 permissive permissive JJ cord-292657-gq3965se 44 14 host host NN cord-292657-gq3965se 44 15 exposure exposure NN cord-292657-gq3965se 44 16 ( ( -LRB- cord-292657-gq3965se 44 17 intra intra JJ cord-292657-gq3965se 44 18 or or CC cord-292657-gq3965se 44 19 inter inter JJ cord-292657-gq3965se 44 20 species species NN cord-292657-gq3965se 44 21 spill spill NN cord-292657-gq3965se 44 22 over over IN cord-292657-gq3965se 44 23 / / SYM cord-292657-gq3965se 44 24 intermediate intermediate JJ cord-292657-gq3965se 44 25 host host NN cord-292657-gq3965se 44 26 ) ) -RRB- cord-292657-gq3965se 44 27 seems seem VBZ cord-292657-gq3965se 44 28 an an DT cord-292657-gq3965se 44 29 important important JJ cord-292657-gq3965se 44 30 determining determine VBG cord-292657-gq3965se 44 31 factor factor NN cord-292657-gq3965se 44 32 for for IN cord-292657-gq3965se 44 33 pathogenic pathogenic JJ cord-292657-gq3965se 44 34 evolution evolution NN cord-292657-gq3965se 44 35 among among IN cord-292657-gq3965se 44 36 human human JJ cord-292657-gq3965se 44 37 population population NN cord-292657-gq3965se 44 38 [ [ -LRB- cord-292657-gq3965se 44 39 13 13 CD cord-292657-gq3965se 44 40 , , , cord-292657-gq3965se 44 41 14 14 CD cord-292657-gq3965se 44 42 ] ] -RRB- cord-292657-gq3965se 44 43 . . . cord-292657-gq3965se 45 1 But but CC cord-292657-gq3965se 45 2 the the DT cord-292657-gq3965se 45 3 natural natural JJ cord-292657-gq3965se 45 4 way way NN cord-292657-gq3965se 45 5 of of IN cord-292657-gq3965se 45 6 genetic genetic JJ cord-292657-gq3965se 45 7 adaptation adaptation NN cord-292657-gq3965se 45 8 of of IN cord-292657-gq3965se 45 9 the the DT cord-292657-gq3965se 45 10 current current JJ cord-292657-gq3965se 45 11 SARS SARS NNP cord-292657-gq3965se 45 12 - - HYPH cord-292657-gq3965se 45 13 CoV-2 CoV-2 NNP cord-292657-gq3965se 45 14 is be VBZ cord-292657-gq3965se 45 15 not not RB cord-292657-gq3965se 45 16 understood understand VBN cord-292657-gq3965se 45 17 yet yet RB cord-292657-gq3965se 45 18 . . . cord-292657-gq3965se 46 1 In in IN cord-292657-gq3965se 46 2 this this DT cord-292657-gq3965se 46 3 part part NN cord-292657-gq3965se 46 4 , , , cord-292657-gq3965se 46 5 based base VBN cord-292657-gq3965se 46 6 on on IN cord-292657-gq3965se 46 7 its -PRON- PRP$ cord-292657-gq3965se 46 8 published publish VBN cord-292657-gq3965se 46 9 sequence sequence NN cord-292657-gq3965se 46 10 analysis analysis NN cord-292657-gq3965se 46 11 we -PRON- PRP cord-292657-gq3965se 46 12 will will MD cord-292657-gq3965se 46 13 try try VB cord-292657-gq3965se 46 14 to to TO cord-292657-gq3965se 46 15 figure figure VB cord-292657-gq3965se 46 16 out out RP cord-292657-gq3965se 46 17 how how WRB cord-292657-gq3965se 46 18 the the DT cord-292657-gq3965se 46 19 molecular molecular JJ cord-292657-gq3965se 46 20 genetic genetic JJ cord-292657-gq3965se 46 21 variation variation NN cord-292657-gq3965se 46 22 leads lead VBZ cord-292657-gq3965se 46 23 to to IN cord-292657-gq3965se 46 24 viral viral JJ cord-292657-gq3965se 46 25 adaptation adaptation NN cord-292657-gq3965se 46 26 to to IN cord-292657-gq3965se 46 27 the the DT cord-292657-gq3965se 46 28 human human JJ cord-292657-gq3965se 46 29 host host NN cord-292657-gq3965se 46 30 body body NN cord-292657-gq3965se 46 31 environment environment NN cord-292657-gq3965se 46 32 . . . cord-292657-gq3965se 47 1 Out out IN cord-292657-gq3965se 47 2 of of IN cord-292657-gq3965se 47 3 the the DT cord-292657-gq3965se 47 4 corona corona NN cord-292657-gq3965se 47 5 virus virus NN cord-292657-gq3965se 47 6 society society NN cord-292657-gq3965se 47 7 , , , cord-292657-gq3965se 47 8 the the DT cord-292657-gq3965se 47 9 SARS SARS NNP cord-292657-gq3965se 47 10 - - HYPH cord-292657-gq3965se 47 11 CoV-2 CoV-2 NNP cord-292657-gq3965se 47 12 can can MD cord-292657-gq3965se 47 13 cause cause VB cord-292657-gq3965se 47 14 infection infection NN cord-292657-gq3965se 47 15 to to IN cord-292657-gq3965se 47 16 humans human NNS cord-292657-gq3965se 47 17 like like IN cord-292657-gq3965se 47 18 other other JJ cord-292657-gq3965se 47 19 human human NN cord-292657-gq3965se 48 1 CoV. CoV. NNP cord-292657-gq3965se 49 1 But but CC cord-292657-gq3965se 49 2 we -PRON- PRP cord-292657-gq3965se 49 3 have have VBP cord-292657-gq3965se 49 4 to to TO cord-292657-gq3965se 49 5 think think VB cord-292657-gq3965se 49 6 about about IN cord-292657-gq3965se 49 7 the the DT cord-292657-gq3965se 49 8 fact fact NN cord-292657-gq3965se 49 9 that that IN cord-292657-gq3965se 49 10 , , , cord-292657-gq3965se 49 11 its -PRON- PRP$ cord-292657-gq3965se 49 12 infection infection NN cord-292657-gq3965se 49 13 severity severity NN cord-292657-gq3965se 49 14 is be VBZ cord-292657-gq3965se 49 15 deadly deadly JJ cord-292657-gq3965se 49 16 enough enough RB cord-292657-gq3965se 49 17 compared compare VBN cord-292657-gq3965se 49 18 to to IN cord-292657-gq3965se 49 19 all all PDT cord-292657-gq3965se 49 20 the the DT cord-292657-gq3965se 49 21 other other JJ cord-292657-gq3965se 49 22 human human JJ cord-292657-gq3965se 49 23 COVID covid NN cord-292657-gq3965se 49 24 . . . cord-292657-gq3965se 50 1 This this DT cord-292657-gq3965se 50 2 fact fact NN cord-292657-gq3965se 50 3 can can MD cord-292657-gq3965se 50 4 be be VB cord-292657-gq3965se 50 5 explained explain VBN cord-292657-gq3965se 50 6 by by IN cord-292657-gq3965se 50 7 the the DT cord-292657-gq3965se 50 8 unique unique JJ cord-292657-gq3965se 50 9 disease disease NN cord-292657-gq3965se 50 10 causing cause VBG cord-292657-gq3965se 50 11 genetic genetic JJ cord-292657-gq3965se 50 12 character character NN cord-292657-gq3965se 50 13 of of IN cord-292657-gq3965se 50 14 SARS SARS NNP cord-292657-gq3965se 50 15 - - HYPH cord-292657-gq3965se 50 16 CoV-2 CoV-2 NNP cord-292657-gq3965se 50 17 . . . cord-292657-gq3965se 51 1 Receptor receptor NN cord-292657-gq3965se 51 2 recognition recognition NN cord-292657-gq3965se 51 3 is be VBZ cord-292657-gq3965se 51 4 the the DT cord-292657-gq3965se 51 5 initial initial JJ cord-292657-gq3965se 51 6 and and CC cord-292657-gq3965se 51 7 important important JJ cord-292657-gq3965se 51 8 genetic genetic JJ cord-292657-gq3965se 51 9 determinant determinant NN cord-292657-gq3965se 51 10 for for IN cord-292657-gq3965se 51 11 a a DT cord-292657-gq3965se 51 12 viral viral JJ cord-292657-gq3965se 51 13 infection infection NN cord-292657-gq3965se 51 14 . . . cord-292657-gq3965se 52 1 Evidence evidence NN cord-292657-gq3965se 52 2 shows show VBZ cord-292657-gq3965se 52 3 that that IN cord-292657-gq3965se 52 4 viral viral JJ cord-292657-gq3965se 52 5 spike spike NN cord-292657-gq3965se 52 6 protein protein NN cord-292657-gq3965se 52 7 structural structural JJ cord-292657-gq3965se 52 8 specificity specificity NN cord-292657-gq3965se 52 9 decides decide VBZ cord-292657-gq3965se 52 10 the the DT cord-292657-gq3965se 52 11 host host NN cord-292657-gq3965se 52 12 range range NN cord-292657-gq3965se 52 13 in in IN cord-292657-gq3965se 52 14 human human JJ cord-292657-gq3965se 52 15 CoV cov NN cord-292657-gq3965se 52 16 like like IN cord-292657-gq3965se 52 17 , , , cord-292657-gq3965se 52 18 SARS SARS NNP cord-292657-gq3965se 52 19 and and CC cord-292657-gq3965se 52 20 MERS MERS NNP cord-292657-gq3965se 52 21 by by IN cord-292657-gq3965se 52 22 exerting exert VBG cord-292657-gq3965se 52 23 human human JJ cord-292657-gq3965se 52 24 cell cell NN cord-292657-gq3965se 52 25 receptor receptor NN cord-292657-gq3965se 52 26 recognition recognition NN cord-292657-gq3965se 52 27 [ [ -LRB- cord-292657-gq3965se 52 28 14 14 CD cord-292657-gq3965se 52 29 , , , cord-292657-gq3965se 52 30 15 15 CD cord-292657-gq3965se 52 31 ] ] -RRB- cord-292657-gq3965se 52 32 . . . cord-292657-gq3965se 53 1 The the DT cord-292657-gq3965se 53 2 SARS SARS NNP cord-292657-gq3965se 53 3 - - HYPH cord-292657-gq3965se 53 4 CoV CoV NNP cord-292657-gq3965se 53 5 and and CC cord-292657-gq3965se 53 6 SARS SARS NNP cord-292657-gq3965se 53 7 - - HYPH cord-292657-gq3965se 53 8 CoV-2 CoV-2 NNP cord-292657-gq3965se 53 9 both both DT cord-292657-gq3965se 53 10 shows show VBZ cord-292657-gq3965se 53 11 same same JJ cord-292657-gq3965se 53 12 binding bind VBG cord-292657-gq3965se 53 13 affinity affinity NN cord-292657-gq3965se 53 14 with with IN cord-292657-gq3965se 53 15 the the DT cord-292657-gq3965se 53 16 ACE2 ACE2 NNP cord-292657-gq3965se 54 1 ( ( -LRB- cord-292657-gq3965se 54 2 Angiotension Angiotension NNP cord-292657-gq3965se 54 3 converting convert VBG cord-292657-gq3965se 54 4 enzyme enzyme NN cord-292657-gq3965se 54 5 2 2 CD cord-292657-gq3965se 54 6 ) ) -RRB- cord-292657-gq3965se 54 7 receptor receptor NN cord-292657-gq3965se 54 8 in in IN cord-292657-gq3965se 54 9 human human JJ cord-292657-gq3965se 54 10 cells cell NNS cord-292657-gq3965se 54 11 . . . cord-292657-gq3965se 55 1 So so CC cord-292657-gq3965se 55 2 it -PRON- PRP cord-292657-gq3965se 55 3 is be VBZ cord-292657-gq3965se 55 4 important important JJ cord-292657-gq3965se 55 5 to to TO cord-292657-gq3965se 55 6 understand understand VB cord-292657-gq3965se 55 7 the the DT cord-292657-gq3965se 55 8 molecular molecular JJ cord-292657-gq3965se 55 9 genetic genetic JJ cord-292657-gq3965se 55 10 property property NN cord-292657-gq3965se 55 11 of of IN cord-292657-gq3965se 55 12 the the DT cord-292657-gq3965se 55 13 spike spike NN cord-292657-gq3965se 55 14 protein protein NN cord-292657-gq3965se 55 15 receptor receptor NN cord-292657-gq3965se 55 16 recognition recognition NN cord-292657-gq3965se 55 17 site site NN cord-292657-gq3965se 55 18 of of IN cord-292657-gq3965se 55 19 SARS SARS NNP cord-292657-gq3965se 55 20 - - HYPH cord-292657-gq3965se 55 21 CoV-2 CoV-2 NNP cord-292657-gq3965se 55 22 which which WDT cord-292657-gq3965se 55 23 genetically genetically RB cord-292657-gq3965se 55 24 isolates isolate VBZ cord-292657-gq3965se 55 25 this this DT cord-292657-gq3965se 55 26 variant variant NN cord-292657-gq3965se 55 27 from from IN cord-292657-gq3965se 55 28 other other JJ cord-292657-gq3965se 55 29 corona corona NN cord-292657-gq3965se 55 30 virusand virusand NNP cord-292657-gq3965se 55 31 decides decide VBZ cord-292657-gq3965se 55 32 the the DT cord-292657-gq3965se 55 33 human human JJ cord-292657-gq3965se 55 34 cell cell NN cord-292657-gq3965se 55 35 specificity specificity NN cord-292657-gq3965se 55 36 and and CC cord-292657-gq3965se 55 37 infection infection NN cord-292657-gq3965se 55 38 in in IN cord-292657-gq3965se 55 39 more more RBR cord-292657-gq3965se 55 40 severe severe JJ cord-292657-gq3965se 55 41 form form NN cord-292657-gq3965se 55 42 . . . cord-292657-gq3965se 56 1 The the DT cord-292657-gq3965se 56 2 human human JJ cord-292657-gq3965se 56 3 cell cell NN cord-292657-gq3965se 56 4 receptor receptor NN cord-292657-gq3965se 56 5 binding bind VBG cord-292657-gq3965se 56 6 domain domain NN cord-292657-gq3965se 56 7 of of IN cord-292657-gq3965se 56 8 the the DT cord-292657-gq3965se 56 9 spike spike NN cord-292657-gq3965se 56 10 protein protein NN cord-292657-gq3965se 56 11 of of IN cord-292657-gq3965se 56 12 SARS SARS NNP cord-292657-gq3965se 56 13 - - HYPH cord-292657-gq3965se 56 14 CoV-2 CoV-2 NNP cord-292657-gq3965se 56 15 is be VBZ cord-292657-gq3965se 56 16 mutated mutate VBN cord-292657-gq3965se 56 17 in in IN cord-292657-gq3965se 56 18 5 5 CD cord-292657-gq3965se 56 19 - - SYM cord-292657-gq3965se 56 20 6 6 CD cord-292657-gq3965se 56 21 amino amino NN cord-292657-gq3965se 56 22 acid acid NN cord-292657-gq3965se 56 23 residues residue NNS cord-292657-gq3965se 56 24 and and CC cord-292657-gq3965se 56 25 shows show VBZ cord-292657-gq3965se 56 26 high high JJ cord-292657-gq3965se 56 27 specific specific JJ cord-292657-gq3965se 56 28 ACE2 ACE2 NNP cord-292657-gq3965se 56 29 human human JJ cord-292657-gq3965se 56 30 cell cell NN cord-292657-gq3965se 56 31 receptor receptor NN cord-292657-gq3965se 56 32 binding bind VBG cord-292657-gq3965se 56 33 affinity affinity NN cord-292657-gq3965se 56 34 . . . cord-292657-gq3965se 57 1 The the DT cord-292657-gq3965se 57 2 spike spike NN cord-292657-gq3965se 57 3 protein protein NN cord-292657-gq3965se 57 4 has have VBZ cord-292657-gq3965se 57 5 two two CD cord-292657-gq3965se 57 6 subunits subunit NNS cord-292657-gq3965se 57 7 ( ( -LRB- cord-292657-gq3965se 57 8 S1 S1 NNP cord-292657-gq3965se 57 9 and and CC cord-292657-gq3965se 57 10 S2 S2 NNP cord-292657-gq3965se 57 11 ) ) -RRB- cord-292657-gq3965se 57 12 and and CC cord-292657-gq3965se 57 13 at at IN cord-292657-gq3965se 57 14 the the DT cord-292657-gq3965se 57 15 junction junction NN cord-292657-gq3965se 57 16 , , , cord-292657-gq3965se 57 17 there there EX cord-292657-gq3965se 57 18 is be VBZ cord-292657-gq3965se 57 19 a a DT cord-292657-gq3965se 57 20 polybasic polybasic JJ cord-292657-gq3965se 57 21 cleavage cleavage NN cord-292657-gq3965se 57 22 site site NN cord-292657-gq3965se 57 23 present present NN cord-292657-gq3965se 57 24 which which WDT cord-292657-gq3965se 57 25 allows allow VBZ cord-292657-gq3965se 57 26 furin furin NN cord-292657-gq3965se 57 27 or or CC cord-292657-gq3965se 57 28 protease protease NN cord-292657-gq3965se 57 29 mediated mediate VBN cord-292657-gq3965se 57 30 cleavage cleavage NN cord-292657-gq3965se 57 31 and and CC cord-292657-gq3965se 57 32 insertion insertion NN cord-292657-gq3965se 57 33 of of IN cord-292657-gq3965se 57 34 prolin prolin NNP cord-292657-gq3965se 57 35 like like IN cord-292657-gq3965se 57 36 molecule molecule NN cord-292657-gq3965se 57 37 which which WDT cord-292657-gq3965se 57 38 adds add VBZ cord-292657-gq3965se 57 39 0-linked 0-linked CD cord-292657-gq3965se 57 40 glycan glycan NN cord-292657-gq3965se 57 41 molecules molecule NNS cord-292657-gq3965se 57 42 resulting result VBG cord-292657-gq3965se 57 43 the the DT cord-292657-gq3965se 57 44 flanking flanking NN cord-292657-gq3965se 57 45 of of IN cord-292657-gq3965se 57 46 the the DT cord-292657-gq3965se 57 47 two two CD cord-292657-gq3965se 57 48 cleavages cleavage NNS cord-292657-gq3965se 57 49 [ [ -LRB- cord-292657-gq3965se 57 50 2 2 CD cord-292657-gq3965se 57 51 , , , cord-292657-gq3965se 57 52 29 29 CD cord-292657-gq3965se 57 53 ] ] -RRB- cord-292657-gq3965se 57 54 . . . cord-292657-gq3965se 58 1 Thus thus RB cord-292657-gq3965se 58 2 it -PRON- PRP cord-292657-gq3965se 58 3 is be VBZ cord-292657-gq3965se 58 4 clear clear JJ cord-292657-gq3965se 58 5 that that IN cord-292657-gq3965se 58 6 , , , cord-292657-gq3965se 58 7 the the DT cord-292657-gq3965se 58 8 uniqueness uniqueness NN cord-292657-gq3965se 58 9 of of IN cord-292657-gq3965se 58 10 spike spike NN cord-292657-gq3965se 58 11 protein protein NN cord-292657-gq3965se 58 12 is be VBZ cord-292657-gq3965se 58 13 crucial crucial JJ cord-292657-gq3965se 58 14 for for IN cord-292657-gq3965se 58 15 the the DT cord-292657-gq3965se 58 16 genetic genetic JJ cord-292657-gq3965se 58 17 isolation isolation NN cord-292657-gq3965se 58 18 of of IN cord-292657-gq3965se 58 19 SARS SARS NNP cord-292657-gq3965se 58 20 - - HYPH cord-292657-gq3965se 58 21 CoV-2 CoV-2 NNP cord-292657-gq3965se 58 22 and and CC cord-292657-gq3965se 58 23 its -PRON- PRP$ cord-292657-gq3965se 58 24 high high JJ cord-292657-gq3965se 58 25 affinity affinity NN cord-292657-gq3965se 58 26 binding bind VBG cord-292657-gq3965se 58 27 to to IN cord-292657-gq3965se 58 28 human human JJ cord-292657-gq3965se 58 29 cells cell NNS cord-292657-gq3965se 58 30 . . . cord-292657-gq3965se 59 1 But but CC cord-292657-gq3965se 59 2 it -PRON- PRP cord-292657-gq3965se 59 3 has have VBZ cord-292657-gq3965se 59 4 been be VBN cord-292657-gq3965se 59 5 observed observe VBN cord-292657-gq3965se 59 6 from from IN cord-292657-gq3965se 59 7 receptor receptor NN cord-292657-gq3965se 59 8 homology homology NN cord-292657-gq3965se 59 9 study study NN cord-292657-gq3965se 59 10 that that IN cord-292657-gq3965se 59 11 , , , cord-292657-gq3965se 59 12 the the DT cord-292657-gq3965se 59 13 SARS SARS NNP cord-292657-gq3965se 59 14 - - HYPH cord-292657-gq3965se 59 15 CoV-2 CoV-2 NNP cord-292657-gq3965se 59 16 also also RB cord-292657-gq3965se 59 17 has have VBZ cord-292657-gq3965se 59 18 affinity affinity NN cord-292657-gq3965se 59 19 to to IN cord-292657-gq3965se 59 20 the the DT cord-292657-gq3965se 59 21 ACE2 ACE2 NNP cord-292657-gq3965se 59 22 receptor receptor NN cord-292657-gq3965se 59 23 in in IN cord-292657-gq3965se 59 24 other other JJ cord-292657-gq3965se 59 25 animals animal NNS cord-292657-gq3965se 59 26 like like IN cord-292657-gq3965se 59 27 the the DT cord-292657-gq3965se 59 28 humans human NNS cord-292657-gq3965se 59 29 . . . cord-292657-gq3965se 60 1 Now now RB cord-292657-gq3965se 60 2 the the DT cord-292657-gq3965se 60 3 next next JJ cord-292657-gq3965se 60 4 question question NN cord-292657-gq3965se 60 5 come come VBN cord-292657-gq3965se 60 6 in in IN cord-292657-gq3965se 60 7 mind mind NN cord-292657-gq3965se 60 8 that that IN cord-292657-gq3965se 60 9 , , , cord-292657-gq3965se 60 10 how how WRB cord-292657-gq3965se 60 11 SARS SARS NNP cord-292657-gq3965se 60 12 - - : cord-292657-gq3965se 60 13 CoV-2 CoV-2 NNP cord-292657-gq3965se 60 14 particularly particularly RB cord-292657-gq3965se 60 15 becomes become VBZ cord-292657-gq3965se 60 16 pandemic pandemic NN cord-292657-gq3965se 60 17 for for IN cord-292657-gq3965se 60 18 human human JJ cord-292657-gq3965se 60 19 beings being NNS cord-292657-gq3965se 60 20 with with IN cord-292657-gq3965se 60 21 high high JJ cord-292657-gq3965se 60 22 mortality mortality NN cord-292657-gq3965se 60 23 rate rate NN cord-292657-gq3965se 60 24 compared compare VBN cord-292657-gq3965se 60 25 to to IN cord-292657-gq3965se 60 26 the the DT cord-292657-gq3965se 60 27 other other JJ cord-292657-gq3965se 60 28 one one NN cord-292657-gq3965se 60 29 . . . cord-292657-gq3965se 61 1 For for IN cord-292657-gq3965se 61 2 a a DT cord-292657-gq3965se 61 3 specific specific JJ cord-292657-gq3965se 61 4 host host NN cord-292657-gq3965se 61 5 pathogen pathogen NN cord-292657-gq3965se 61 6 interaction interaction NN cord-292657-gq3965se 61 7 and and CC cord-292657-gq3965se 61 8 disease disease NN cord-292657-gq3965se 61 9 establishment establishment NN cord-292657-gq3965se 61 10 , , , cord-292657-gq3965se 61 11 except except IN cord-292657-gq3965se 61 12 the the DT cord-292657-gq3965se 61 13 receptor receptor NN cord-292657-gq3965se 61 14 recognition recognition NN cord-292657-gq3965se 61 15 by by IN cord-292657-gq3965se 61 16 the the DT cord-292657-gq3965se 61 17 unique unique JJ cord-292657-gq3965se 61 18 spike spike NN cord-292657-gq3965se 61 19 protein protein NN cord-292657-gq3965se 61 20 domain domain NN cord-292657-gq3965se 61 21 of of IN cord-292657-gq3965se 61 22 the the DT cord-292657-gq3965se 61 23 virus virus NN cord-292657-gq3965se 61 24 , , , cord-292657-gq3965se 61 25 the the DT cord-292657-gq3965se 61 26 receptor receptor NN cord-292657-gq3965se 61 27 variation variation NN cord-292657-gq3965se 61 28 of of IN cord-292657-gq3965se 61 29 the the DT cord-292657-gq3965se 61 30 host host NN cord-292657-gq3965se 61 31 cell cell NN cord-292657-gq3965se 61 32 also also RB cord-292657-gq3965se 61 33 is be VBZ cord-292657-gq3965se 61 34 an an DT cord-292657-gq3965se 61 35 important important JJ cord-292657-gq3965se 61 36 genetic genetic JJ cord-292657-gq3965se 61 37 character character NN cord-292657-gq3965se 61 38 . . . cord-292657-gq3965se 62 1 The the DT cord-292657-gq3965se 62 2 human human JJ cord-292657-gq3965se 62 3 ACE2 ACE2 NNP cord-292657-gq3965se 62 4 cell cell NN cord-292657-gq3965se 62 5 receptor receptor NN cord-292657-gq3965se 62 6 is be VBZ cord-292657-gq3965se 62 7 genetically genetically RB cord-292657-gq3965se 62 8 identical identical JJ cord-292657-gq3965se 62 9 from from IN cord-292657-gq3965se 62 10 other other JJ cord-292657-gq3965se 62 11 animals animal NNS cord-292657-gq3965se 62 12 for for IN cord-292657-gq3965se 62 13 the the DT cord-292657-gq3965se 62 14 recognition recognition NN cord-292657-gq3965se 62 15 by by IN cord-292657-gq3965se 62 16 the the DT cord-292657-gq3965se 62 17 corona corona NN cord-292657-gq3965se 62 18 virus virus NN cord-292657-gq3965se 62 19 as as IN cord-292657-gq3965se 62 20 observed observe VBN cord-292657-gq3965se 62 21 for for IN cord-292657-gq3965se 62 22 MERS MERS NNP cord-292657-gq3965se 62 23 - - HYPH cord-292657-gq3965se 62 24 DPP4 DPP4 NNP cord-292657-gq3965se 62 25 receptor receptor NN cord-292657-gq3965se 62 26 binding bind VBG cord-292657-gq3965se 62 27 property property NN cord-292657-gq3965se 62 28 [ [ -LRB- cord-292657-gq3965se 62 29 8 8 CD cord-292657-gq3965se 62 30 ] ] -RRB- cord-292657-gq3965se 62 31 . . . cord-292657-gq3965se 63 1 Moreover moreover RB cord-292657-gq3965se 63 2 it -PRON- PRP cord-292657-gq3965se 63 3 has have VBZ cord-292657-gq3965se 63 4 been be VBN cord-292657-gq3965se 63 5 observed observe VBN cord-292657-gq3965se 63 6 that that IN cord-292657-gq3965se 63 7 , , , cord-292657-gq3965se 63 8 there there EX cord-292657-gq3965se 63 9 are be VBP cord-292657-gq3965se 63 10 several several JJ cord-292657-gq3965se 63 11 ACE2 ACE2 NNP cord-292657-gq3965se 63 12 receptor receptor NN cord-292657-gq3965se 63 13 variants variant NNS cord-292657-gq3965se 63 14 present present JJ cord-292657-gq3965se 63 15 in in IN cord-292657-gq3965se 63 16 different different JJ cord-292657-gq3965se 63 17 human human JJ cord-292657-gq3965se 63 18 populations population NNS cord-292657-gq3965se 63 19 and and CC cord-292657-gq3965se 63 20 several several JJ cord-292657-gq3965se 63 21 variant variant NN cord-292657-gq3965se 63 22 out out IN cord-292657-gq3965se 63 23 of of IN cord-292657-gq3965se 63 24 it -PRON- PRP cord-292657-gq3965se 63 25 may may MD cord-292657-gq3965se 63 26 restrict restrict VB cord-292657-gq3965se 63 27 or or CC cord-292657-gq3965se 63 28 reduce reduce VB cord-292657-gq3965se 63 29 the the DT cord-292657-gq3965se 63 30 CoV CoV NNP cord-292657-gq3965se 63 31 specific specific NNP cord-292657-gq3965se 63 32 association association NNP cord-292657-gq3965se 63 33 with with IN cord-292657-gq3965se 63 34 it -PRON- PRP cord-292657-gq3965se 63 35 . . . cord-292657-gq3965se 64 1 From from IN cord-292657-gq3965se 64 2 the the DT cord-292657-gq3965se 64 3 recent recent JJ cord-292657-gq3965se 64 4 genetic genetic JJ cord-292657-gq3965se 64 5 analysis analysis NN cord-292657-gq3965se 64 6 of of IN cord-292657-gq3965se 64 7 the the DT cord-292657-gq3965se 64 8 SARS SARS NNP cord-292657-gq3965se 64 9 - - HYPH cord-292657-gq3965se 64 10 CoV-2 CoV-2 NNP cord-292657-gq3965se 64 11 ACE2 ACE2 NNP cord-292657-gq3965se 64 12 human human JJ cord-292657-gq3965se 64 13 receptor receptor NN cord-292657-gq3965se 64 14 variation variation NN cord-292657-gq3965se 64 15 in in IN cord-292657-gq3965se 64 16 different different JJ cord-292657-gq3965se 64 17 population population NN cord-292657-gq3965se 64 18 shows show VBZ cord-292657-gq3965se 64 19 that that IN cord-292657-gq3965se 64 20 , , , cord-292657-gq3965se 64 21 the the DT cord-292657-gq3965se 64 22 expression expression NN cord-292657-gq3965se 64 23 pattern pattern NN cord-292657-gq3965se 64 24 of of IN cord-292657-gq3965se 64 25 ACE2 ACE2 NNP cord-292657-gq3965se 64 26 receptor receptor NN cord-292657-gq3965se 64 27 is be VBZ cord-292657-gq3965se 64 28 an an DT cord-292657-gq3965se 64 29 important important JJ cord-292657-gq3965se 64 30 determining determine VBG cord-292657-gq3965se 64 31 factor factor NN cord-292657-gq3965se 64 32 for for IN cord-292657-gq3965se 64 33 the the DT cord-292657-gq3965se 64 34 pathogen pathogen NN cord-292657-gq3965se 64 35 susceptibility susceptibility NN cord-292657-gq3965se 64 36 . . . cord-292657-gq3965se 65 1 For for IN cord-292657-gq3965se 65 2 example example NN cord-292657-gq3965se 65 3 , , , cord-292657-gq3965se 65 4 among among IN cord-292657-gq3965se 65 5 the the DT cord-292657-gq3965se 65 6 Asians Asians NNPS cord-292657-gq3965se 65 7 specifically specifically RB cord-292657-gq3965se 65 8 , , , cord-292657-gq3965se 65 9 the the DT cord-292657-gq3965se 65 10 Chinese chinese JJ cord-292657-gq3965se 65 11 population population NN cord-292657-gq3965se 65 12 do do VBP cord-292657-gq3965se 65 13 n't not RB cord-292657-gq3965se 65 14 have have VB cord-292657-gq3965se 65 15 the the DT cord-292657-gq3965se 65 16 natural natural JJ cord-292657-gq3965se 65 17 resistant resistant JJ cord-292657-gq3965se 65 18 mutated mutate VBN cord-292657-gq3965se 65 19 gene gene NN cord-292657-gq3965se 65 20 against against IN cord-292657-gq3965se 65 21 CoV cov NN cord-292657-gq3965se 65 22 infection infection NN cord-292657-gq3965se 65 23 and and CC cord-292657-gq3965se 65 24 express express VB cord-292657-gq3965se 65 25 high high JJ cord-292657-gq3965se 65 26 level level NN cord-292657-gq3965se 65 27 of of IN cord-292657-gq3965se 65 28 ACE2 ACE2 NNP cord-292657-gq3965se 65 29 receptors receptor NNS cord-292657-gq3965se 65 30 in in IN cord-292657-gq3965se 65 31 tissue tissue NN cord-292657-gq3965se 65 32 [ [ -LRB- cord-292657-gq3965se 65 33 3 3 CD cord-292657-gq3965se 65 34 ] ] -RRB- cord-292657-gq3965se 65 35 . . . cord-292657-gq3965se 66 1 So so CC cord-292657-gq3965se 66 2 it -PRON- PRP cord-292657-gq3965se 66 3 is be VBZ cord-292657-gq3965se 66 4 revealed reveal VBN cord-292657-gq3965se 66 5 that that IN cord-292657-gq3965se 66 6 , , , cord-292657-gq3965se 66 7 not not RB cord-292657-gq3965se 66 8 only only RB cord-292657-gq3965se 66 9 the the DT cord-292657-gq3965se 66 10 genetic genetic JJ cord-292657-gq3965se 66 11 uniqueness uniqueness NN cord-292657-gq3965se 66 12 of of IN cord-292657-gq3965se 66 13 the the DT cord-292657-gq3965se 66 14 spike spike NN cord-292657-gq3965se 66 15 protein protein NN cord-292657-gq3965se 66 16 of of IN cord-292657-gq3965se 66 17 pathogen pathogen NN cord-292657-gq3965se 66 18 , , , cord-292657-gq3965se 66 19 but but CC cord-292657-gq3965se 66 20 also also RB cord-292657-gq3965se 66 21 the the DT cord-292657-gq3965se 66 22 receptor receptor NN cord-292657-gq3965se 66 23 of of IN cord-292657-gq3965se 66 24 host host NN cord-292657-gq3965se 66 25 cell cell NN cord-292657-gq3965se 66 26 is be VBZ cord-292657-gq3965se 66 27 equally equally RB cord-292657-gq3965se 66 28 important important JJ cord-292657-gq3965se 66 29 for for IN cord-292657-gq3965se 66 30 the the DT cord-292657-gq3965se 66 31 successful successful JJ cord-292657-gq3965se 66 32 establishment establishment NN cord-292657-gq3965se 66 33 of of IN cord-292657-gq3965se 66 34 COVID-19 covid-19 JJ cord-292657-gq3965se 66 35 outbreak outbreak NN cord-292657-gq3965se 66 36 . . . cord-292657-gq3965se 67 1 Now now RB cord-292657-gq3965se 67 2 the the DT cord-292657-gq3965se 67 3 next next JJ cord-292657-gq3965se 67 4 question question NN cord-292657-gq3965se 67 5 is be VBZ cord-292657-gq3965se 67 6 how how WRB cord-292657-gq3965se 67 7 this this DT cord-292657-gq3965se 67 8 unique unique JJ cord-292657-gq3965se 67 9 host host NN cord-292657-gq3965se 67 10 - - HYPH cord-292657-gq3965se 67 11 pathogen pathogen NN cord-292657-gq3965se 67 12 interactive interactive JJ cord-292657-gq3965se 67 13 characteristic characteristic NN cord-292657-gq3965se 67 14 has have VBZ cord-292657-gq3965se 67 15 been be VBN cord-292657-gq3965se 67 16 developed develop VBN cord-292657-gq3965se 67 17 under under IN cord-292657-gq3965se 67 18 the the DT cord-292657-gq3965se 67 19 influence influence NN cord-292657-gq3965se 67 20 of of IN cord-292657-gq3965se 67 21 host host NN cord-292657-gq3965se 67 22 environment environment NN cord-292657-gq3965se 67 23 . . . cord-292657-gq3965se 68 1 From from IN cord-292657-gq3965se 68 2 different different JJ cord-292657-gq3965se 68 3 recent recent JJ cord-292657-gq3965se 68 4 research research NN cord-292657-gq3965se 68 5 evidence evidence NN cord-292657-gq3965se 68 6 based base VBN cord-292657-gq3965se 68 7 on on IN cord-292657-gq3965se 68 8 phylogenetic phylogenetic JJ cord-292657-gq3965se 68 9 analysis analysis NN cord-292657-gq3965se 68 10 of of IN cord-292657-gq3965se 68 11 complete complete JJ cord-292657-gq3965se 68 12 genome genome NN cord-292657-gq3965se 68 13 sequence sequence NN cord-292657-gq3965se 68 14 of of IN cord-292657-gq3965se 68 15 SARS SARS NNP cord-292657-gq3965se 68 16 - - HYPH cord-292657-gq3965se 68 17 C0V-2 C0V-2 NNP cord-292657-gq3965se 68 18 shows show VBZ cord-292657-gq3965se 68 19 indication indication NN cord-292657-gq3965se 68 20 of of IN cord-292657-gq3965se 68 21 the the DT cord-292657-gq3965se 68 22 evolution evolution NN cord-292657-gq3965se 68 23 of of IN cord-292657-gq3965se 68 24 a a DT cord-292657-gq3965se 68 25 rapid rapid JJ cord-292657-gq3965se 68 26 , , , cord-292657-gq3965se 68 27 diverse diverse JJ cord-292657-gq3965se 68 28 and and CC cord-292657-gq3965se 68 29 sequential sequential JJ cord-292657-gq3965se 68 30 genome genome NN cord-292657-gq3965se 68 31 variability variability NN cord-292657-gq3965se 68 32 whichwe whichwe NNP cord-292657-gq3965se 68 33 will will MD cord-292657-gq3965se 68 34 analyze analyze VB cord-292657-gq3965se 68 35 by by IN cord-292657-gq3965se 68 36 molecular molecular JJ cord-292657-gq3965se 68 37 genetic genetic JJ cord-292657-gq3965se 68 38 perspective perspective NN cord-292657-gq3965se 68 39 from from IN cord-292657-gq3965se 68 40 four four CD cord-292657-gq3965se 68 41 different different JJ cord-292657-gq3965se 68 42 angles angle NNS cord-292657-gq3965se 68 43 . . . cord-292657-gq3965se 69 1 First first RB cord-292657-gq3965se 69 2 we -PRON- PRP cord-292657-gq3965se 69 3 will will MD cord-292657-gq3965se 69 4 analyses analyse VBZ cord-292657-gq3965se 69 5 the the DT cord-292657-gq3965se 69 6 genome genome NN cord-292657-gq3965se 69 7 variability variability NN cord-292657-gq3965se 69 8 in in IN cord-292657-gq3965se 69 9 terms term NNS cord-292657-gq3965se 69 10 of of IN cord-292657-gq3965se 69 11 the the DT cord-292657-gq3965se 69 12 diversity diversity NN cord-292657-gq3965se 69 13 of of IN cord-292657-gq3965se 69 14 the the DT cord-292657-gq3965se 69 15 SARS SARS NNP cord-292657-gq3965se 69 16 - - HYPH cord-292657-gq3965se 69 17 CoV-2 CoV-2 NNP cord-292657-gq3965se 69 18 genome genome NN cord-292657-gq3965se 69 19 in in IN cord-292657-gq3965se 69 20 different different JJ cord-292657-gq3965se 69 21 host host NN cord-292657-gq3965se 69 22 species specie NNS cord-292657-gq3965se 69 23 . . . cord-292657-gq3965se 70 1 This this DT cord-292657-gq3965se 70 2 is be VBZ cord-292657-gq3965se 70 3 revealed reveal VBN cord-292657-gq3965se 70 4 that that IN cord-292657-gq3965se 70 5 SARS SARS NNP cord-292657-gq3965se 70 6 - - HYPH cord-292657-gq3965se 70 7 CoV-2 CoV-2 NNP cord-292657-gq3965se 70 8 show show VBP cord-292657-gq3965se 70 9 overall overall RB cord-292657-gq3965se 70 10 96 96 CD cord-292657-gq3965se 70 11 % % NN cord-292657-gq3965se 70 12 sequence sequence NN cord-292657-gq3965se 70 13 similarity similarity NN cord-292657-gq3965se 70 14 with with IN cord-292657-gq3965se 70 15 the the DT cord-292657-gq3965se 70 16 bat bat NN cord-292657-gq3965se 70 17 SARS SARS NNP cord-292657-gq3965se 70 18 - - HYPH cord-292657-gq3965se 70 19 CoV CoV NNP cord-292657-gq3965se 70 20 like like IN cord-292657-gq3965se 70 21 corona corona NNP cord-292657-gq3965se 70 22 virus virus NN cord-292657-gq3965se 70 23 but but CC cord-292657-gq3965se 70 24 the the DT cord-292657-gq3965se 70 25 similarity similarity NN cord-292657-gq3965se 70 26 differs differ VBZ cord-292657-gq3965se 70 27 in in IN cord-292657-gq3965se 70 28 the the DT cord-292657-gq3965se 70 29 spike spike NN cord-292657-gq3965se 70 30 protein protein NN cord-292657-gq3965se 70 31 receptor receptor NN cord-292657-gq3965se 70 32 binding bind VBG cord-292657-gq3965se 70 33 domain domain NN cord-292657-gq3965se 70 34 ( ( -LRB- cord-292657-gq3965se 70 35 RBD RBD NNP cord-292657-gq3965se 70 36 ) ) -RRB- cord-292657-gq3965se 70 37 [ [ -LRB- cord-292657-gq3965se 70 38 32 32 CD cord-292657-gq3965se 70 39 , , , cord-292657-gq3965se 70 40 35 35 CD cord-292657-gq3965se 70 41 ] ] -RRB- cord-292657-gq3965se 70 42 . . . cord-292657-gq3965se 71 1 We -PRON- PRP cord-292657-gq3965se 71 2 got get VBD cord-292657-gq3965se 71 3 this this DT cord-292657-gq3965se 71 4 kind kind NN cord-292657-gq3965se 71 5 of of IN cord-292657-gq3965se 71 6 sequence sequence NN cord-292657-gq3965se 71 7 similarity similarity NN cord-292657-gq3965se 71 8 in in IN cord-292657-gq3965se 71 9 other other JJ cord-292657-gq3965se 71 10 human human JJ cord-292657-gq3965se 71 11 corona corona NN cord-292657-gq3965se 71 12 virus virus NN cord-292657-gq3965se 71 13 where where WRB cord-292657-gq3965se 71 14 bat bat NN cord-292657-gq3965se 71 15 have have VBP cord-292657-gq3965se 71 16 been be VBN cord-292657-gq3965se 71 17 found find VBN cord-292657-gq3965se 71 18 as as IN cord-292657-gq3965se 71 19 the the DT cord-292657-gq3965se 71 20 common common JJ cord-292657-gq3965se 71 21 ancestral ancestral JJ cord-292657-gq3965se 71 22 reservoir reservoir NN cord-292657-gq3965se 71 23 of of IN cord-292657-gq3965se 71 24 the the DT cord-292657-gq3965se 71 25 pathogen pathogen NN cord-292657-gq3965se 71 26 [ [ -LRB- cord-292657-gq3965se 71 27 10 10 CD cord-292657-gq3965se 71 28 ] ] -RRB- cord-292657-gq3965se 71 29 . . . cord-292657-gq3965se 72 1 On on IN cord-292657-gq3965se 72 2 the the DT cord-292657-gq3965se 72 3 other other JJ cord-292657-gq3965se 72 4 hand hand NN cord-292657-gq3965se 72 5 , , , cord-292657-gq3965se 72 6 a a DT cord-292657-gq3965se 72 7 similar similar JJ cord-292657-gq3965se 72 8 kind kind NN cord-292657-gq3965se 72 9 of of IN cord-292657-gq3965se 72 10 corona corona NN cord-292657-gq3965se 72 11 virus virus NN cord-292657-gq3965se 72 12 with with IN cord-292657-gq3965se 72 13 SARS SARS NNP cord-292657-gq3965se 72 14 - - HYPH cord-292657-gq3965se 72 15 CoV-2 CoV-2 NNP cord-292657-gq3965se 72 16 has have VBZ cord-292657-gq3965se 72 17 been be VBN cord-292657-gq3965se 72 18 identified identify VBN cord-292657-gq3965se 72 19 in in IN cord-292657-gq3965se 72 20 Malayan malayan JJ cord-292657-gq3965se 72 21 pangolins pangolin NNS cord-292657-gq3965se 72 22 , , , cord-292657-gq3965se 72 23 which which WDT cord-292657-gq3965se 72 24 shows show VBZ cord-292657-gq3965se 72 25 strong strong JJ cord-292657-gq3965se 72 26 and and CC cord-292657-gq3965se 72 27 almost almost RB cord-292657-gq3965se 72 28 identical identical JJ cord-292657-gq3965se 72 29 similarity similarity NN cord-292657-gq3965se 72 30 with with IN cord-292657-gq3965se 72 31 SARS SARS NNP cord-292657-gq3965se 72 32 - - HYPH cord-292657-gq3965se 72 33 CoV CoV NNP cord-292657-gq3965se 72 34 in in IN cord-292657-gq3965se 72 35 the the DT cord-292657-gq3965se 72 36 spike spike NN cord-292657-gq3965se 72 37 protein protein NN cord-292657-gq3965se 72 38 RBD RBD NNP cord-292657-gq3965se 72 39 . . . cord-292657-gq3965se 73 1 Thus thus RB cord-292657-gq3965se 73 2 these these DT cord-292657-gq3965se 73 3 pangolins pangolin NNS cord-292657-gq3965se 73 4 can can MD cord-292657-gq3965se 73 5 be be VB cord-292657-gq3965se 73 6 interpreted interpret VBN cord-292657-gq3965se 73 7 as as IN cord-292657-gq3965se 73 8 the the DT cord-292657-gq3965se 73 9 intermediate intermediate JJ cord-292657-gq3965se 73 10 host host NN cord-292657-gq3965se 73 11 for for IN cord-292657-gq3965se 73 12 SARS SARS NNP cord-292657-gq3965se 73 13 - - HYPH cord-292657-gq3965se 73 14 CoV-2 CoV-2 NNP cord-292657-gq3965se 73 15 [ [ -LRB- cord-292657-gq3965se 73 16 34 34 CD cord-292657-gq3965se 73 17 ] ] -RRB- cord-292657-gq3965se 73 18 . . . cord-292657-gq3965se 74 1 These these DT cord-292657-gq3965se 74 2 evidences evidence NNS cord-292657-gq3965se 74 3 indicate indicate VBP cord-292657-gq3965se 74 4 toward toward IN cord-292657-gq3965se 74 5 the the DT cord-292657-gq3965se 74 6 sequential sequential JJ cord-292657-gq3965se 74 7 evolution evolution NN cord-292657-gq3965se 74 8 of of IN cord-292657-gq3965se 74 9 the the DT cord-292657-gq3965se 74 10 spike spike NN cord-292657-gq3965se 74 11 protein protein NN cord-292657-gq3965se 74 12 RBD RBD NNP cord-292657-gq3965se 74 13 by by IN cord-292657-gq3965se 74 14 species species NN cord-292657-gq3965se 74 15 spill spill NN cord-292657-gq3965se 74 16 over over IN cord-292657-gq3965se 74 17 nature nature NN cord-292657-gq3965se 74 18 of of IN cord-292657-gq3965se 74 19 the the DT cord-292657-gq3965se 74 20 virus virus NN cord-292657-gq3965se 74 21 . . . cord-292657-gq3965se 75 1 The the DT cord-292657-gq3965se 75 2 variability variability NN cord-292657-gq3965se 75 3 of of IN cord-292657-gq3965se 75 4 SARS SARS NNP cord-292657-gq3965se 75 5 - - HYPH cord-292657-gq3965se 75 6 CoV-2 CoV-2 NNP cord-292657-gq3965se 75 7 viral viral JJ cord-292657-gq3965se 75 8 genome genome NN cord-292657-gq3965se 75 9 in in IN cord-292657-gq3965se 75 10 different different JJ cord-292657-gq3965se 75 11 species specie NNS cord-292657-gq3965se 75 12 confirms confirm VBZ cord-292657-gq3965se 75 13 of of IN cord-292657-gq3965se 75 14 its -PRON- PRP$ cord-292657-gq3965se 75 15 animal animal NN cord-292657-gq3965se 75 16 origin origin NN cord-292657-gq3965se 75 17 and and CC cord-292657-gq3965se 75 18 subsequent subsequent JJ cord-292657-gq3965se 75 19 evolution evolution NN cord-292657-gq3965se 75 20 of of IN cord-292657-gq3965se 75 21 by by IN cord-292657-gq3965se 75 22 jumping jump VBG cord-292657-gq3965se 75 23 species species NN cord-292657-gq3965se 75 24 nature nature NN cord-292657-gq3965se 75 25 . . . cord-292657-gq3965se 76 1 But but CC cord-292657-gq3965se 76 2 none none NN cord-292657-gq3965se 76 3 of of IN cord-292657-gq3965se 76 4 the the DT cord-292657-gq3965se 76 5 sequence sequence NN cord-292657-gq3965se 76 6 similarity similarity NN cord-292657-gq3965se 76 7 of of IN cord-292657-gq3965se 76 8 SARS SARS NNP cord-292657-gq3965se 76 9 - - HYPH cord-292657-gq3965se 76 10 CoV CoV NNP cord-292657-gq3965se 76 11 with with IN cord-292657-gq3965se 76 12 bat bat NN cord-292657-gq3965se 76 13 or or CC cord-292657-gq3965se 76 14 pangolins pangolin NNS cord-292657-gq3965se 76 15 has have VBZ cord-292657-gq3965se 76 16 been be VBN cord-292657-gq3965se 76 17 found find VBN cord-292657-gq3965se 76 18 based base VBN cord-292657-gq3965se 76 19 on on IN cord-292657-gq3965se 76 20 the the DT cord-292657-gq3965se 76 21 unique unique JJ cord-292657-gq3965se 76 22 polybasic polybasic JJ cord-292657-gq3965se 76 23 cleavage cleavage NN cord-292657-gq3965se 76 24 site site NN cord-292657-gq3965se 76 25 , , , cord-292657-gq3965se 76 26 which which WDT cord-292657-gq3965se 76 27 can can MD cord-292657-gq3965se 76 28 be be VB cord-292657-gq3965se 76 29 considered consider VBN cord-292657-gq3965se 76 30 as as IN cord-292657-gq3965se 76 31 next next JJ cord-292657-gq3965se 76 32 level level NN cord-292657-gq3965se 76 33 of of IN cord-292657-gq3965se 76 34 determining determine VBG cord-292657-gq3965se 76 35 criteria criterion NNS cord-292657-gq3965se 76 36 for for IN cord-292657-gq3965se 76 37 SARS SARS NNP cord-292657-gq3965se 76 38 - - HYPH cord-292657-gq3965se 76 39 CoV-2 CoV-2 NNP cord-292657-gq3965se 76 40 human human JJ cord-292657-gq3965se 76 41 cell cell NN cord-292657-gq3965se 76 42 receptor receptor NN cord-292657-gq3965se 76 43 specificity specificity NN cord-292657-gq3965se 76 44 and and CC cord-292657-gq3965se 76 45 pathogenic pathogenic JJ cord-292657-gq3965se 76 46 severity severity NN cord-292657-gq3965se 76 47 as as IN cord-292657-gq3965se 76 48 observed observe VBN cord-292657-gq3965se 76 49 in in IN cord-292657-gq3965se 76 50 case case NN cord-292657-gq3965se 76 51 of of IN cord-292657-gq3965se 76 52 MERS MERS NNP cord-292657-gq3965se 77 1 an an DT cord-292657-gq3965se 77 2 avian avian JJ cord-292657-gq3965se 77 3 influenza influenza NN cord-292657-gq3965se 77 4 virus virus NN cord-292657-gq3965se 77 5 [ [ -LRB- cord-292657-gq3965se 77 6 1 1 CD cord-292657-gq3965se 77 7 , , , cord-292657-gq3965se 77 8 20 20 CD cord-292657-gq3965se 77 9 ] ] -RRB- cord-292657-gq3965se 77 10 . . . cord-292657-gq3965se 78 1 The the DT cord-292657-gq3965se 78 2 insertion insertion NN cord-292657-gq3965se 78 3 of of IN cord-292657-gq3965se 78 4 unique unique JJ cord-292657-gq3965se 78 5 poly poly JJ cord-292657-gq3965se 78 6 basic basic JJ cord-292657-gq3965se 78 7 furin furin NN cord-292657-gq3965se 78 8 cleavage cleavage NN cord-292657-gq3965se 78 9 site site NN cord-292657-gq3965se 78 10 in in IN cord-292657-gq3965se 78 11 SARS SARS NNP cord-292657-gq3965se 78 12 - - HYPH cord-292657-gq3965se 78 13 CoV-2 CoV-2 NNP cord-292657-gq3965se 78 14 is be VBZ cord-292657-gq3965se 78 15 probably probably RB cord-292657-gq3965se 78 16 acquired acquire VBN cord-292657-gq3965se 78 17 during during IN cord-292657-gq3965se 78 18 human human JJ cord-292657-gq3965se 78 19 to to IN cord-292657-gq3965se 78 20 human human JJ cord-292657-gq3965se 78 21 transmission transmission NN cord-292657-gq3965se 78 22 . . . cord-292657-gq3965se 79 1 Thus thus RB cord-292657-gq3965se 79 2 the the DT cord-292657-gq3965se 79 3 second second JJ cord-292657-gq3965se 79 4 indication indication NN cord-292657-gq3965se 79 5 of of IN cord-292657-gq3965se 79 6 molecular molecular JJ cord-292657-gq3965se 79 7 diversity diversity NN cord-292657-gq3965se 79 8 and and CC cord-292657-gq3965se 79 9 evolution evolution NN cord-292657-gq3965se 79 10 will will MD cord-292657-gq3965se 79 11 be be VB cord-292657-gq3965se 79 12 analyzed analyze VBN cord-292657-gq3965se 79 13 in in IN cord-292657-gq3965se 79 14 terms term NNS cord-292657-gq3965se 79 15 of of IN cord-292657-gq3965se 79 16 different different JJ cord-292657-gq3965se 79 17 subtypes subtype NNS cord-292657-gq3965se 79 18 of of IN cord-292657-gq3965se 79 19 the the DT cord-292657-gq3965se 79 20 virus virus NN cord-292657-gq3965se 79 21 , , , cord-292657-gq3965se 79 22 which which WDT cord-292657-gq3965se 79 23 has have VBZ cord-292657-gq3965se 79 24 been be VBN cord-292657-gq3965se 79 25 found find VBN cord-292657-gq3965se 79 26 in in IN cord-292657-gq3965se 79 27 different different JJ cord-292657-gq3965se 79 28 human human JJ cord-292657-gq3965se 79 29 population population NN cord-292657-gq3965se 79 30 throughout throughout IN cord-292657-gq3965se 79 31 the the DT cord-292657-gq3965se 79 32 world world NN cord-292657-gq3965se 79 33 . . . cord-292657-gq3965se 80 1 Most Most JJS cord-292657-gq3965se 80 2 recent recent JJ cord-292657-gq3965se 80 3 research research NN cord-292657-gq3965se 80 4 work work NN cord-292657-gq3965se 80 5 suggests suggest VBZ cord-292657-gq3965se 80 6 three three CD cord-292657-gq3965se 80 7 different different JJ cord-292657-gq3965se 80 8 genetically genetically RB cord-292657-gq3965se 80 9 close close JJ cord-292657-gq3965se 80 10 sub sub NN cord-292657-gq3965se 80 11 types type NNS cord-292657-gq3965se 80 12 of of IN cord-292657-gq3965se 80 13 the the DT cord-292657-gq3965se 80 14 SARS SARS NNP cord-292657-gq3965se 80 15 - - HYPH cord-292657-gq3965se 80 16 CoV-2 CoV-2 NNP cord-292657-gq3965se 80 17 with with IN cord-292657-gq3965se 80 18 small small JJ cord-292657-gq3965se 80 19 amino amino NN cord-292657-gq3965se 80 20 acid acid NN cord-292657-gq3965se 80 21 sequence sequence NN cord-292657-gq3965se 80 22 variations variation NNS cord-292657-gq3965se 80 23 which which WDT cord-292657-gq3965se 80 24 can can MD cord-292657-gq3965se 80 25 also also RB cord-292657-gq3965se 80 26 be be VB cord-292657-gq3965se 80 27 linked link VBN cord-292657-gq3965se 80 28 with with IN cord-292657-gq3965se 80 29 continental continental JJ cord-292657-gq3965se 80 30 and and CC cord-292657-gq3965se 80 31 ethnic ethnic JJ cord-292657-gq3965se 80 32 specificity specificity NN cord-292657-gq3965se 80 33 . . . cord-292657-gq3965se 81 1 This this DT cord-292657-gq3965se 81 2 research research NN cord-292657-gq3965se 81 3 shows show VBZ cord-292657-gq3965se 81 4 that that IN cord-292657-gq3965se 81 5 the the DT cord-292657-gq3965se 81 6 A a DT cord-292657-gq3965se 81 7 subtype subtype NN cord-292657-gq3965se 81 8 is be VBZ cord-292657-gq3965se 81 9 considered consider VBN cord-292657-gq3965se 81 10 as as IN cord-292657-gq3965se 81 11 the the DT cord-292657-gq3965se 81 12 ancient ancient JJ cord-292657-gq3965se 81 13 form form NN cord-292657-gq3965se 81 14 of of IN cord-292657-gq3965se 81 15 SARS SARS NNP cord-292657-gq3965se 81 16 - - HYPH cord-292657-gq3965se 81 17 CoV-2 CoV-2 NNP cord-292657-gq3965se 81 18 which which WDT cord-292657-gq3965se 81 19 shows show VBZ cord-292657-gq3965se 81 20 close close JJ cord-292657-gq3965se 81 21 similarity similarity NN cord-292657-gq3965se 81 22 with with IN cord-292657-gq3965se 81 23 bat bat NN cord-292657-gq3965se 81 24 corona corona NN cord-292657-gq3965se 81 25 virus virus NN cord-292657-gq3965se 81 26 and and CC cord-292657-gq3965se 81 27 generates generate VBZ cord-292657-gq3965se 81 28 the the DT cord-292657-gq3965se 81 29 other other JJ cord-292657-gq3965se 81 30 two two CD cord-292657-gq3965se 81 31 different different JJ cord-292657-gq3965se 81 32 subtypes subtype NNS cord-292657-gq3965se 81 33 , , , cord-292657-gq3965se 81 34 the the DT cord-292657-gq3965se 81 35 B b NN cord-292657-gq3965se 81 36 and and CC cord-292657-gq3965se 81 37 C. C. NNP cord-292657-gq3965se 82 1 The the DT cord-292657-gq3965se 82 2 sub sub NN cord-292657-gq3965se 82 3 type type NN cord-292657-gq3965se 82 4 B b NN cord-292657-gq3965se 82 5 , , , cord-292657-gq3965se 82 6 which which WDT cord-292657-gq3965se 82 7 is be VBZ cord-292657-gq3965se 82 8 mainly mainly RB cord-292657-gq3965se 82 9 profound profound JJ cord-292657-gq3965se 82 10 in in IN cord-292657-gq3965se 82 11 China China NNP cord-292657-gq3965se 82 12 and and CC cord-292657-gq3965se 82 13 East east JJ cord-292657-gq3965se 82 14 Asian asian JJ cord-292657-gq3965se 82 15 continents continent NNS cord-292657-gq3965se 82 16 is be VBZ cord-292657-gq3965se 82 17 the the DT cord-292657-gq3965se 82 18 genetic genetic JJ cord-292657-gq3965se 82 19 variant variant NN cord-292657-gq3965se 82 20 of of IN cord-292657-gq3965se 82 21 the the DT cord-292657-gq3965se 82 22 subtype subtype NN cord-292657-gq3965se 83 1 A a DT cord-292657-gq3965se 83 2 by by IN cord-292657-gq3965se 83 3 two two CD cord-292657-gq3965se 83 4 mutations mutation NNS cord-292657-gq3965se 83 5 , , , cord-292657-gq3965se 83 6 ( ( -LRB- cord-292657-gq3965se 83 7 synonymous synonymous JJ cord-292657-gq3965se 83 8 and and CC cord-292657-gq3965se 83 9 nonsynonymous nonsynonymous JJ cord-292657-gq3965se 83 10 ) ) -RRB- cord-292657-gq3965se 83 11 and and CC cord-292657-gq3965se 83 12 not not RB cord-292657-gq3965se 83 13 found find VBN cord-292657-gq3965se 83 14 outside outside IN cord-292657-gq3965se 83 15 Asia Asia NNP cord-292657-gq3965se 83 16 . . . cord-292657-gq3965se 84 1 The the DT cord-292657-gq3965se 84 2 B b NN cord-292657-gq3965se 84 3 subtypes subtype NNS cord-292657-gq3965se 84 4 has have VBZ cord-292657-gq3965se 84 5 been be VBN cord-292657-gq3965se 84 6 again again RB cord-292657-gq3965se 84 7 mutated mutate VBN cord-292657-gq3965se 84 8 and and CC cord-292657-gq3965se 84 9 generated generate VBD cord-292657-gq3965se 84 10 a a DT cord-292657-gq3965se 84 11 daughter daughter NN cord-292657-gq3965se 84 12 subtype subtype NN cord-292657-gq3965se 84 13 the the DT cord-292657-gq3965se 84 14 C C NNP cord-292657-gq3965se 84 15 variant variant NN cord-292657-gq3965se 84 16 , , , cord-292657-gq3965se 84 17 which which WDT cord-292657-gq3965se 84 18 dominates dominate VBZ cord-292657-gq3965se 84 19 in in IN cord-292657-gq3965se 84 20 Europe Europe NNP cord-292657-gq3965se 84 21 and and CC cord-292657-gq3965se 84 22 represented represent VBN cord-292657-gq3965se 84 23 among among IN cord-292657-gq3965se 84 24 American american JJ cord-292657-gq3965se 84 25 populations population NNS cord-292657-gq3965se 84 26 . . . cord-292657-gq3965se 85 1 The the DT cord-292657-gq3965se 85 2 C c NN cord-292657-gq3965se 85 3 subtype subtype NN cord-292657-gq3965se 85 4 differs differ VBZ cord-292657-gq3965se 85 5 from from IN cord-292657-gq3965se 85 6 B B NNP cord-292657-gq3965se 85 7 by by IN cord-292657-gq3965se 85 8 single single JJ cord-292657-gq3965se 85 9 nonsynonymous nonsynonymous JJ cord-292657-gq3965se 85 10 mutation mutation NN cord-292657-gq3965se 85 11 [ [ -LRB- cord-292657-gq3965se 85 12 9 9 CD cord-292657-gq3965se 85 13 ] ] -RRB- cord-292657-gq3965se 85 14 . . . cord-292657-gq3965se 86 1 This this DT cord-292657-gq3965se 86 2 evidence evidence NN cord-292657-gq3965se 86 3 of of IN cord-292657-gq3965se 86 4 sequential sequential JJ cord-292657-gq3965se 86 5 development development NN cord-292657-gq3965se 86 6 of of IN cord-292657-gq3965se 86 7 different different JJ cord-292657-gq3965se 86 8 sub sub NN cord-292657-gq3965se 86 9 types type NNS cord-292657-gq3965se 86 10 from from IN cord-292657-gq3965se 86 11 a a DT cord-292657-gq3965se 86 12 single single JJ cord-292657-gq3965se 86 13 variant variant NN cord-292657-gq3965se 86 14 among among IN cord-292657-gq3965se 86 15 different different JJ cord-292657-gq3965se 86 16 human human JJ cord-292657-gq3965se 86 17 population population NN cord-292657-gq3965se 86 18 in in IN cord-292657-gq3965se 86 19 different different JJ cord-292657-gq3965se 86 20 continents continent NNS cord-292657-gq3965se 86 21 indicates indicate VBZ cord-292657-gq3965se 86 22 the the DT cord-292657-gq3965se 86 23 continuous continuous JJ cord-292657-gq3965se 86 24 single single JJ cord-292657-gq3965se 86 25 lineage lineage NN cord-292657-gq3965se 86 26 evolution evolution NN cord-292657-gq3965se 86 27 of of IN cord-292657-gq3965se 86 28 the the DT cord-292657-gq3965se 86 29 virus virus NN cord-292657-gq3965se 86 30 during during IN cord-292657-gq3965se 86 31 human human JJ cord-292657-gq3965se 86 32 to to IN cord-292657-gq3965se 86 33 human human JJ cord-292657-gq3965se 86 34 species species NN cord-292657-gq3965se 86 35 spill spill VBP cord-292657-gq3965se 86 36 over over RP cord-292657-gq3965se 86 37 . . . cord-292657-gq3965se 87 1 Moreover moreover RB cord-292657-gq3965se 87 2 , , , cord-292657-gq3965se 87 3 the the DT cord-292657-gq3965se 87 4 different different JJ cord-292657-gq3965se 87 5 subtypes subtype NNS cord-292657-gq3965se 87 6 of of IN cord-292657-gq3965se 87 7 SARS SARS NNP cord-292657-gq3965se 87 8 - - HYPH cord-292657-gq3965se 87 9 CoV-2 CoV-2 NNP cord-292657-gq3965se 87 10 can can MD cord-292657-gq3965se 87 11 be be VB cord-292657-gq3965se 87 12 linked link VBN cord-292657-gq3965se 87 13 with with IN cord-292657-gq3965se 87 14 different different JJ cord-292657-gq3965se 87 15 genetic genetic JJ cord-292657-gq3965se 87 16 setup setup NN cord-292657-gq3965se 87 17 of of IN cord-292657-gq3965se 87 18 the the DT cord-292657-gq3965se 87 19 host host NN cord-292657-gq3965se 87 20 population population NN cord-292657-gq3965se 87 21 in in IN cord-292657-gq3965se 87 22 the the DT cord-292657-gq3965se 87 23 world world NN cord-292657-gq3965se 87 24 . . . cord-292657-gq3965se 88 1 Now now RB cord-292657-gq3965se 88 2 , , , cord-292657-gq3965se 88 3 as as IN cord-292657-gq3965se 88 4 previously previously RB cord-292657-gq3965se 88 5 described describe VBN cord-292657-gq3965se 88 6 , , , cord-292657-gq3965se 88 7 different different JJ cord-292657-gq3965se 88 8 SARS SARS NNP cord-292657-gq3965se 88 9 - - HYPH cord-292657-gq3965se 88 10 CoV-2 CoV-2 NNP cord-292657-gq3965se 88 11 infected infected JJ cord-292657-gq3965se 88 12 population population NN cord-292657-gq3965se 88 13 in in IN cord-292657-gq3965se 88 14 the the DT cord-292657-gq3965se 88 15 world world NN cord-292657-gq3965se 88 16 shows show VBZ cord-292657-gq3965se 88 17 genome genome NN cord-292657-gq3965se 88 18 variation variation NN cord-292657-gq3965se 88 19 and and CC cord-292657-gq3965se 88 20 expression expression NN cord-292657-gq3965se 88 21 of of IN cord-292657-gq3965se 88 22 ACE2 ACE2 NNP cord-292657-gq3965se 88 23 receptor receptor NN cord-292657-gq3965se 88 24 coding coding NN cord-292657-gq3965se 88 25 sequence sequence NN cord-292657-gq3965se 88 26 which which WDT cord-292657-gq3965se 88 27 can can MD cord-292657-gq3965se 88 28 affect affect VB cord-292657-gq3965se 88 29 the the DT cord-292657-gq3965se 88 30 binding binding NN cord-292657-gq3965se 88 31 and and CC cord-292657-gq3965se 88 32 susceptibility susceptibility NN cord-292657-gq3965se 88 33 of of IN cord-292657-gq3965se 88 34 the the DT cord-292657-gq3965se 88 35 SARS SARS NNP cord-292657-gq3965se 88 36 - - HYPH cord-292657-gq3965se 88 37 CoV-2 CoV-2 NNP cord-292657-gq3965se 88 38 , , , cord-292657-gq3965se 88 39 it -PRON- PRP cord-292657-gq3965se 88 40 can can MD cord-292657-gq3965se 88 41 be be VB cord-292657-gq3965se 88 42 predicted predict VBN cord-292657-gq3965se 88 43 that that IN cord-292657-gq3965se 88 44 , , , cord-292657-gq3965se 88 45 this this DT cord-292657-gq3965se 88 46 ACE2 ACE2 NNP cord-292657-gq3965se 88 47 receptor receptor NN cord-292657-gq3965se 88 48 variation variation NN cord-292657-gq3965se 88 49 created create VBD cord-292657-gq3965se 88 50 intense intense JJ cord-292657-gq3965se 88 51 selective selective JJ cord-292657-gq3965se 88 52 pressure pressure NN cord-292657-gq3965se 88 53 to to IN cord-292657-gq3965se 88 54 the the DT cord-292657-gq3965se 88 55 circulating circulate VBG cord-292657-gq3965se 88 56 SARS SARS NNP cord-292657-gq3965se 88 57 - - HYPH cord-292657-gq3965se 88 58 CoV-2 CoV-2 NNP cord-292657-gq3965se 88 59 genome genome NN cord-292657-gq3965se 88 60 and and CC cord-292657-gq3965se 88 61 as as IN cord-292657-gq3965se 88 62 a a DT cord-292657-gq3965se 88 63 result result NN cord-292657-gq3965se 88 64 of of IN cord-292657-gq3965se 88 65 this this DT cord-292657-gq3965se 88 66 the the DT cord-292657-gq3965se 88 67 virus virus NN cord-292657-gq3965se 88 68 adapted adapt VBN cord-292657-gq3965se 88 69 to to TO cord-292657-gq3965se 88 70 establish establish VB cord-292657-gq3965se 88 71 infection infection NN cord-292657-gq3965se 88 72 with with IN cord-292657-gq3965se 88 73 its -PRON- PRP$ cord-292657-gq3965se 88 74 different different JJ cord-292657-gq3965se 88 75 genetic genetic JJ cord-292657-gq3965se 88 76 variants variant NNS cord-292657-gq3965se 88 77 in in IN cord-292657-gq3965se 88 78 a a DT cord-292657-gq3965se 88 79 pandemic pandemic NN cord-292657-gq3965se 88 80 form form NN cord-292657-gq3965se 88 81 throughout throughout IN cord-292657-gq3965se 88 82 the the DT cord-292657-gq3965se 88 83 world world NN cord-292657-gq3965se 88 84 [ [ -LRB- cord-292657-gq3965se 88 85 3 3 CD cord-292657-gq3965se 88 86 ] ] -RRB- cord-292657-gq3965se 88 87 . . . cord-292657-gq3965se 89 1 Every every DT cord-292657-gq3965se 89 2 disease disease NN cord-292657-gq3965se 89 3 when when WRB cord-292657-gq3965se 89 4 it -PRON- PRP cord-292657-gq3965se 89 5 becomes become VBZ cord-292657-gq3965se 89 6 a a DT cord-292657-gq3965se 89 7 pandemic pandemic NN cord-292657-gq3965se 89 8 it -PRON- PRP cord-292657-gq3965se 89 9 is be VBZ cord-292657-gq3965se 89 10 revealed reveal VBN cord-292657-gq3965se 89 11 sequentially sequentially RB cord-292657-gq3965se 89 12 through through IN cord-292657-gq3965se 89 13 several several JJ cord-292657-gq3965se 89 14 stages stage NNS cord-292657-gq3965se 89 15 , , , cord-292657-gq3965se 89 16 which which WDT cord-292657-gq3965se 89 17 also also RB cord-292657-gq3965se 89 18 indicates indicate VBZ cord-292657-gq3965se 89 19 toward toward IN cord-292657-gq3965se 89 20 the the DT cord-292657-gq3965se 89 21 evolutionary evolutionary JJ cord-292657-gq3965se 89 22 nature nature NN cord-292657-gq3965se 89 23 of of IN cord-292657-gq3965se 89 24 the the DT cord-292657-gq3965se 89 25 pathogen pathogen NN cord-292657-gq3965se 89 26 with with IN cord-292657-gq3965se 89 27 the the DT cord-292657-gq3965se 89 28 host host NN cord-292657-gq3965se 89 29 body body NN cord-292657-gq3965se 89 30 . . . cord-292657-gq3965se 90 1 So so RB cord-292657-gq3965se 90 2 the the DT cord-292657-gq3965se 90 3 third third JJ cord-292657-gq3965se 90 4 molecular molecular JJ cord-292657-gq3965se 90 5 genetic genetic JJ cord-292657-gq3965se 90 6 evolution evolution NN cord-292657-gq3965se 90 7 of of IN cord-292657-gq3965se 90 8 the the DT cord-292657-gq3965se 90 9 COVID-19 COVID-19 NNP cord-292657-gq3965se 90 10 will will MD cord-292657-gq3965se 90 11 be be VB cord-292657-gq3965se 90 12 analysis analysis NN cord-292657-gq3965se 90 13 based base VBN cord-292657-gq3965se 90 14 on on IN cord-292657-gq3965se 90 15 the the DT cord-292657-gq3965se 90 16 different different JJ cord-292657-gq3965se 90 17 phages phage NNS cord-292657-gq3965se 90 18 of of IN cord-292657-gq3965se 90 19 the the DT cord-292657-gq3965se 90 20 pandemic pandemic NN cord-292657-gq3965se 90 21 . . . cord-292657-gq3965se 91 1 If if IN cord-292657-gq3965se 91 2 we -PRON- PRP cord-292657-gq3965se 91 3 categories categorie VBZ cord-292657-gq3965se 91 4 the the DT cord-292657-gq3965se 91 5 COVID-19 covid-19 JJ cord-292657-gq3965se 91 6 outbreak outbreak NN cord-292657-gq3965se 91 7 into into IN cord-292657-gq3965se 91 8 different different JJ cord-292657-gq3965se 91 9 stages stage NNS cord-292657-gq3965se 91 10 , , , cord-292657-gq3965se 91 11 it -PRON- PRP cord-292657-gq3965se 91 12 has have VBZ cord-292657-gq3965se 91 13 been be VBN cord-292657-gq3965se 91 14 found find VBN cord-292657-gq3965se 91 15 that that IN cord-292657-gq3965se 91 16 at at IN cord-292657-gq3965se 91 17 the the DT cord-292657-gq3965se 91 18 initial initial JJ cord-292657-gq3965se 91 19 stage stage NN cord-292657-gq3965se 91 20 it -PRON- PRP cord-292657-gq3965se 91 21 is be VBZ cord-292657-gq3965se 91 22 reported report VBN cord-292657-gq3965se 91 23 in in IN cord-292657-gq3965se 91 24 some some DT cord-292657-gq3965se 91 25 individuals individual NNS cord-292657-gq3965se 91 26 in in IN cord-292657-gq3965se 91 27 Hunan Hunan NNP cord-292657-gq3965se 91 28 market market NN cord-292657-gq3965se 91 29 of of IN cord-292657-gq3965se 91 30 Wuhan Wuhan NNP cord-292657-gq3965se 91 31 , , , cord-292657-gq3965se 91 32 in in IN cord-292657-gq3965se 91 33 Hubei Hubei NNP cord-292657-gq3965se 91 34 province province NN cord-292657-gq3965se 91 35 of of IN cord-292657-gq3965se 91 36 China China NNP cord-292657-gq3965se 91 37 . . . cord-292657-gq3965se 92 1 In in IN cord-292657-gq3965se 92 2 the the DT cord-292657-gq3965se 92 3 second second JJ cord-292657-gq3965se 92 4 phase phase NN cord-292657-gq3965se 92 5 , , , cord-292657-gq3965se 92 6 it -PRON- PRP cord-292657-gq3965se 92 7 has have VBZ cord-292657-gq3965se 92 8 started start VBN cord-292657-gq3965se 92 9 to to TO cord-292657-gq3965se 92 10 found find VBN cord-292657-gq3965se 92 11 as as IN cord-292657-gq3965se 92 12 clustered cluster VBN cord-292657-gq3965se 92 13 form form VBP cord-292657-gq3965se 92 14 in in IN cord-292657-gq3965se 92 15 different different JJ cord-292657-gq3965se 92 16 regions region NNS cord-292657-gq3965se 92 17 of of IN cord-292657-gq3965se 92 18 China China NNP cord-292657-gq3965se 92 19 . . . cord-292657-gq3965se 93 1 Then then RB cord-292657-gq3965se 93 2 in in IN cord-292657-gq3965se 93 3 the the DT cord-292657-gq3965se 93 4 third third JJ cord-292657-gq3965se 93 5 stage stage NN cord-292657-gq3965se 93 6 , , , cord-292657-gq3965se 93 7 the the DT cord-292657-gq3965se 93 8 disease disease NN cord-292657-gq3965se 93 9 has have VBZ cord-292657-gq3965se 93 10 been be VBN cord-292657-gq3965se 93 11 disseminated disseminate VBN cord-292657-gq3965se 93 12 in in IN cord-292657-gq3965se 93 13 different different JJ cord-292657-gq3965se 93 14 parts part NNS cord-292657-gq3965se 93 15 of of IN cord-292657-gq3965se 93 16 Europe Europe NNP cord-292657-gq3965se 93 17 , , , cord-292657-gq3965se 93 18 America America NNP cord-292657-gq3965se 93 19 and and CC cord-292657-gq3965se 93 20 other other JJ cord-292657-gq3965se 93 21 Asian asian JJ cord-292657-gq3965se 93 22 countries country NNS cord-292657-gq3965se 93 23 and and CC cord-292657-gq3965se 93 24 resulted result VBD cord-292657-gq3965se 93 25 as as IN cord-292657-gq3965se 93 26 a a DT cord-292657-gq3965se 93 27 pandemic pandemic NN cord-292657-gq3965se 93 28 . . . cord-292657-gq3965se 94 1 Now now RB cord-292657-gq3965se 94 2 this this DT cord-292657-gq3965se 94 3 different different JJ cord-292657-gq3965se 94 4 phase phase NN cord-292657-gq3965se 94 5 of of IN cord-292657-gq3965se 94 6 disease disease NN cord-292657-gq3965se 94 7 progression progression NN cord-292657-gq3965se 95 1 COVID-19 covid-19 JJ cord-292657-gq3965se 95 2 outbreak outbreak NN cord-292657-gq3965se 95 3 till till IN cord-292657-gq3965se 95 4 now now RB cord-292657-gq3965se 95 5 , , , cord-292657-gq3965se 95 6 can can MD cord-292657-gq3965se 95 7 be be VB cord-292657-gq3965se 95 8 linked link VBN cord-292657-gq3965se 95 9 with with IN cord-292657-gq3965se 95 10 the the DT cord-292657-gq3965se 95 11 evolutionary evolutionary JJ cord-292657-gq3965se 95 12 pattern pattern NN cord-292657-gq3965se 95 13 of of IN cord-292657-gq3965se 95 14 SARS SARS NNP cord-292657-gq3965se 95 15 - - HYPH cord-292657-gq3965se 95 16 CoV-2 CoV-2 NNP cord-292657-gq3965se 95 17 and and CC cord-292657-gq3965se 95 18 its -PRON- PRP$ cord-292657-gq3965se 95 19 different different JJ cord-292657-gq3965se 95 20 subtypes subtype NNS cord-292657-gq3965se 95 21 ( ( -LRB- cord-292657-gq3965se 95 22 as as IN cord-292657-gq3965se 95 23 previously previously RB cord-292657-gq3965se 95 24 described describe VBN cord-292657-gq3965se 95 25 the the DT cord-292657-gq3965se 95 26 A A NNP cord-292657-gq3965se 95 27 , , , cord-292657-gq3965se 95 28 B b NN cord-292657-gq3965se 95 29 , , , cord-292657-gq3965se 95 30 C C NNP cord-292657-gq3965se 95 31 ) ) -RRB- cord-292657-gq3965se 95 32 emerged emerge VBD cord-292657-gq3965se 95 33 in in IN cord-292657-gq3965se 95 34 different different JJ cord-292657-gq3965se 95 35 population population NN cord-292657-gq3965se 95 36 of of IN cord-292657-gq3965se 95 37 the the DT cord-292657-gq3965se 95 38 world world NN cord-292657-gq3965se 95 39 . . . cord-292657-gq3965se 96 1 The the DT cord-292657-gq3965se 96 2 first first JJ cord-292657-gq3965se 96 3 emergence emergence NN cord-292657-gq3965se 96 4 and and CC cord-292657-gq3965se 96 5 case case NN cord-292657-gq3965se 96 6 reports report NNS cord-292657-gq3965se 96 7 of of IN cord-292657-gq3965se 96 8 SARS SARS NNP cord-292657-gq3965se 96 9 - - HYPH cord-292657-gq3965se 96 10 CoV-2 CoV-2 NNP cord-292657-gq3965se 96 11 is be VBZ cord-292657-gq3965se 96 12 found find VBN cord-292657-gq3965se 96 13 in in IN cord-292657-gq3965se 96 14 China China NNP cord-292657-gq3965se 96 15 which which WDT cord-292657-gq3965se 96 16 represents represent VBZ cord-292657-gq3965se 96 17 the the DT cord-292657-gq3965se 96 18 B B NNP cord-292657-gq3965se 96 19 subtype subtype NN cord-292657-gq3965se 96 20 genome genome NN cord-292657-gq3965se 96 21 setup setup NN cord-292657-gq3965se 96 22 and and CC cord-292657-gq3965se 96 23 specific specific JJ cord-292657-gq3965se 96 24 to to IN cord-292657-gq3965se 96 25 this this DT cord-292657-gq3965se 96 26 region region NN cord-292657-gq3965se 96 27 only only RB cord-292657-gq3965se 96 28 . . . cord-292657-gq3965se 97 1 The the DT cord-292657-gq3965se 97 2 B b NN cord-292657-gq3965se 97 3 type type NN cord-292657-gq3965se 97 4 is be VBZ cord-292657-gq3965se 97 5 reported report VBN cord-292657-gq3965se 97 6 to to TO cord-292657-gq3965se 97 7 be be VB cord-292657-gq3965se 97 8 originated originate VBN cord-292657-gq3965se 97 9 from from IN cord-292657-gq3965se 97 10 the the DT cord-292657-gq3965se 97 11 ancestral ancestral JJ cord-292657-gq3965se 97 12 betacorona betacorona NNP cord-292657-gq3965se 97 13 virus virus NN cord-292657-gq3965se 97 14 showing show VBG cord-292657-gq3965se 97 15 close close JJ cord-292657-gq3965se 97 16 sequence sequence NN cord-292657-gq3965se 97 17 similarity similarity NN cord-292657-gq3965se 97 18 . . . cord-292657-gq3965se 98 1 The the DT cord-292657-gq3965se 98 2 association association NN cord-292657-gq3965se 98 3 of of IN cord-292657-gq3965se 98 4 the the DT cord-292657-gq3965se 98 5 virus virus NN cord-292657-gq3965se 98 6 to to IN cord-292657-gq3965se 98 7 the the DT cord-292657-gq3965se 98 8 live live JJ cord-292657-gq3965se 98 9 stock stock NN cord-292657-gq3965se 98 10 animal animal NN cord-292657-gq3965se 98 11 market market NN cord-292657-gq3965se 98 12 in in IN cord-292657-gq3965se 98 13 China China NNP cord-292657-gq3965se 98 14 supports support VBZ cord-292657-gq3965se 98 15 Decoding decode VBG cord-292657-gq3965se 98 16 the the DT cord-292657-gq3965se 98 17 global global JJ cord-292657-gq3965se 98 18 outbreak outbreak NN cord-292657-gq3965se 98 19 of of IN cord-292657-gq3965se 98 20 COVID-19 COVID-19 NNP cord-292657-gq3965se 98 21 : : : cord-292657-gq3965se 98 22 the the DT cord-292657-gq3965se 98 23 nature nature NN cord-292657-gq3965se 98 24 is be VBZ cord-292657-gq3965se 98 25 behind behind IN cord-292657-gq3965se 98 26 the the DT cord-292657-gq3965se 98 27 scene scene NN cord-292657-gq3965se 98 28 this this DT cord-292657-gq3965se 98 29 origin origin NN cord-292657-gq3965se 98 30 [ [ -LRB- cord-292657-gq3965se 98 31 35 35 CD cord-292657-gq3965se 98 32 ] ] -RRB- cord-292657-gq3965se 98 33 . . . cord-292657-gq3965se 99 1 Now now RB cord-292657-gq3965se 99 2 the the DT cord-292657-gq3965se 99 3 pangolin pangolin NN cord-292657-gq3965se 99 4 theory theory NN cord-292657-gq3965se 99 5 as as IN cord-292657-gq3965se 99 6 intermediate intermediate JJ cord-292657-gq3965se 99 7 host host NN cord-292657-gq3965se 99 8 for for IN cord-292657-gq3965se 99 9 the the DT cord-292657-gq3965se 99 10 development development NN cord-292657-gq3965se 99 11 of of IN cord-292657-gq3965se 99 12 the the DT cord-292657-gq3965se 99 13 unique unique JJ cord-292657-gq3965se 99 14 receptor receptor NN cord-292657-gq3965se 99 15 binding bind VBG cord-292657-gq3965se 99 16 site site NN cord-292657-gq3965se 99 17 ( ( -LRB- cord-292657-gq3965se 99 18 RBD RBD NNP cord-292657-gq3965se 99 19 ) ) -RRB- cord-292657-gq3965se 99 20 in in IN cord-292657-gq3965se 99 21 the the DT cord-292657-gq3965se 99 22 SARS SARS NNP cord-292657-gq3965se 99 23 - - HYPH cord-292657-gq3965se 99 24 CoV-2 CoV-2 NNP cord-292657-gq3965se 99 25 can can MD cord-292657-gq3965se 99 26 be be VB cord-292657-gq3965se 99 27 linked link VBN cord-292657-gq3965se 99 28 with with IN cord-292657-gq3965se 99 29 the the DT cord-292657-gq3965se 99 30 report report NN cord-292657-gq3965se 99 31 of of IN cord-292657-gq3965se 99 32 SARS SARS NNP cord-292657-gq3965se 99 33 corona corona NNP cord-292657-gq3965se 99 34 virus virus NN cord-292657-gq3965se 99 35 in in IN cord-292657-gq3965se 99 36 dead dead JJ cord-292657-gq3965se 99 37 pangolins pangolin NNS cord-292657-gq3965se 99 38 from from IN cord-292657-gq3965se 99 39 Guangdong Guangdong NNP cord-292657-gq3965se 99 40 wild wild JJ cord-292657-gq3965se 99 41 life life NN cord-292657-gq3965se 99 42 resource resource NN cord-292657-gq3965se 99 43 in in IN cord-292657-gq3965se 99 44 China China NNP cord-292657-gq3965se 99 45 during during IN cord-292657-gq3965se 99 46 the the DT cord-292657-gq3965se 99 47 period period NN cord-292657-gq3965se 99 48 of of IN cord-292657-gq3965se 99 49 COVID covid JJ cord-292657-gq3965se 99 50 outbreak outbreak NN cord-292657-gq3965se 99 51 in in IN cord-292657-gq3965se 99 52 China China NNP cord-292657-gq3965se 99 53 [ [ -LRB- cord-292657-gq3965se 99 54 34 34 CD cord-292657-gq3965se 99 55 ] ] -RRB- cord-292657-gq3965se 99 56 . . . cord-292657-gq3965se 100 1 This this DT cord-292657-gq3965se 100 2 B b NN cord-292657-gq3965se 100 3 subtype subtype NN cord-292657-gq3965se 100 4 with with IN cord-292657-gq3965se 100 5 the the DT cord-292657-gq3965se 100 6 evolved evolved JJ cord-292657-gq3965se 100 7 genetic genetic JJ cord-292657-gq3965se 100 8 setup setup NN cord-292657-gq3965se 100 9 caused cause VBD cord-292657-gq3965se 100 10 clustered cluster VBN cord-292657-gq3965se 100 11 infection infection NN cord-292657-gq3965se 100 12 in in IN cord-292657-gq3965se 100 13 different different JJ cord-292657-gq3965se 100 14 parts part NNS cord-292657-gq3965se 100 15 of of IN cord-292657-gq3965se 100 16 south south JJ cord-292657-gq3965se 100 17 Asia Asia NNP cord-292657-gq3965se 100 18 soon soon RB cord-292657-gq3965se 100 19 after after IN cord-292657-gq3965se 100 20 it -PRON- PRP cord-292657-gq3965se 100 21 infected infect VBD cord-292657-gq3965se 100 22 a a DT cord-292657-gq3965se 100 23 large large JJ cord-292657-gq3965se 100 24 population population NN cord-292657-gq3965se 100 25 inside inside IN cord-292657-gq3965se 100 26 China China NNP cord-292657-gq3965se 100 27 . . . cord-292657-gq3965se 101 1 Later later RB cord-292657-gq3965se 101 2 , , , cord-292657-gq3965se 101 3 after after IN cord-292657-gq3965se 101 4 a a DT cord-292657-gq3965se 101 5 short short JJ cord-292657-gq3965se 101 6 lag lag NN cord-292657-gq3965se 101 7 period period NN cord-292657-gq3965se 101 8 , , , cord-292657-gq3965se 101 9 the the DT cord-292657-gq3965se 101 10 virus virus NN cord-292657-gq3965se 101 11 is be VBZ cord-292657-gq3965se 101 12 mutated mutate VBN cord-292657-gq3965se 101 13 and and CC cord-292657-gq3965se 101 14 emerged emerge VBD cord-292657-gq3965se 101 15 as as IN cord-292657-gq3965se 101 16 a a DT cord-292657-gq3965se 101 17 pandemic pandemic NN cord-292657-gq3965se 101 18 in in IN cord-292657-gq3965se 101 19 different different JJ cord-292657-gq3965se 101 20 parts part NNS cord-292657-gq3965se 101 21 outside outside IN cord-292657-gq3965se 101 22 Asia Asia NNP cord-292657-gq3965se 101 23 with with IN cord-292657-gq3965se 101 24 another another DT cord-292657-gq3965se 101 25 variant variant NN cord-292657-gq3965se 101 26 , , , cord-292657-gq3965se 101 27 the the DT cord-292657-gq3965se 101 28 C C NNP cord-292657-gq3965se 101 29 subtype subtype NN cord-292657-gq3965se 101 30 , , , cord-292657-gq3965se 101 31 profound profound JJ cord-292657-gq3965se 101 32 in in IN cord-292657-gq3965se 101 33 European european JJ cord-292657-gq3965se 101 34 and and CC cord-292657-gq3965se 101 35 American american JJ cord-292657-gq3965se 101 36 countries country NNS cord-292657-gq3965se 101 37 . . . cord-292657-gq3965se 102 1 This this DT cord-292657-gq3965se 102 2 step step NN cord-292657-gq3965se 102 3 indicates indicate VBZ cord-292657-gq3965se 102 4 another another DT cord-292657-gq3965se 102 5 stage stage NN cord-292657-gq3965se 102 6 of of IN cord-292657-gq3965se 102 7 variation variation NN cord-292657-gq3965se 102 8 with with IN cord-292657-gq3965se 102 9 probable probable JJ cord-292657-gq3965se 102 10 acquisition acquisition NN cord-292657-gq3965se 102 11 of of IN cord-292657-gq3965se 102 12 the the DT cord-292657-gq3965se 102 13 polybasic polybasic JJ cord-292657-gq3965se 102 14 cleavage cleavage NN cord-292657-gq3965se 102 15 site site NN cord-292657-gq3965se 102 16 under under IN cord-292657-gq3965se 102 17 the the DT cord-292657-gq3965se 102 18 influence influence NN cord-292657-gq3965se 102 19 of of IN cord-292657-gq3965se 102 20 unique unique JJ cord-292657-gq3965se 102 21 ACE2 ACE2 NNP cord-292657-gq3965se 102 22 receptor receptor NN cord-292657-gq3965se 102 23 specificity specificity NN cord-292657-gq3965se 102 24 in in IN cord-292657-gq3965se 102 25 these these DT cord-292657-gq3965se 102 26 population population NN cord-292657-gq3965se 102 27 . . . cord-292657-gq3965se 103 1 Thus thus RB cord-292657-gq3965se 103 2 it -PRON- PRP cord-292657-gq3965se 103 3 is be VBZ cord-292657-gq3965se 103 4 clear clear JJ cord-292657-gq3965se 103 5 that that IN cord-292657-gq3965se 103 6 the the DT cord-292657-gq3965se 103 7 viral viral JJ cord-292657-gq3965se 103 8 lineage lineage NN cord-292657-gq3965se 103 9 of of IN cord-292657-gq3965se 103 10 SARS SARS NNP cord-292657-gq3965se 103 11 - - HYPH cord-292657-gq3965se 103 12 CoV-2 CoV-2 NNP cord-292657-gq3965se 103 13 is be VBZ cord-292657-gq3965se 103 14 constantly constantly RB cord-292657-gq3965se 103 15 associated associate VBN cord-292657-gq3965se 103 16 with with IN cord-292657-gq3965se 103 17 evolutionary evolutionary JJ cord-292657-gq3965se 103 18 process process NN cord-292657-gq3965se 103 19 that that WDT cord-292657-gq3965se 103 20 leads lead VBZ cord-292657-gq3965se 103 21 to to IN cord-292657-gq3965se 103 22 the the DT cord-292657-gq3965se 103 23 generation generation NN cord-292657-gq3965se 103 24 of of IN cord-292657-gq3965se 103 25 different different JJ cord-292657-gq3965se 103 26 subtypes subtype NNS cord-292657-gq3965se 103 27 of of IN cord-292657-gq3965se 103 28 the the DT cord-292657-gq3965se 103 29 same same JJ cord-292657-gq3965se 103 30 species specie NNS cord-292657-gq3965se 103 31 which which WDT cord-292657-gq3965se 103 32 is be VBZ cord-292657-gq3965se 103 33 gradually gradually RB cord-292657-gq3965se 103 34 revealed reveal VBN cord-292657-gq3965se 103 35 through through IN cord-292657-gq3965se 103 36 different different JJ cord-292657-gq3965se 103 37 phases phase NNS cord-292657-gq3965se 103 38 of of IN cord-292657-gq3965se 103 39 the the DT cord-292657-gq3965se 103 40 disease disease NN cord-292657-gq3965se 103 41 and and CC cord-292657-gq3965se 103 42 spreaded spread VBN cord-292657-gq3965se 103 43 among among IN cord-292657-gq3965se 103 44 different different JJ cord-292657-gq3965se 103 45 population population NN cord-292657-gq3965se 103 46 of of IN cord-292657-gq3965se 103 47 the the DT cord-292657-gq3965se 103 48 world world NN cord-292657-gq3965se 103 49 causing cause VBG cord-292657-gq3965se 103 50 pandemic pandemic NN cord-292657-gq3965se 103 51 . . . cord-292657-gq3965se 104 1 Evidence evidence NN cord-292657-gq3965se 104 2 form form VB cord-292657-gq3965se 104 3 our -PRON- PRP$ cord-292657-gq3965se 104 4 fourth fourth JJ cord-292657-gq3965se 104 5 and and CC cord-292657-gq3965se 104 6 last last JJ cord-292657-gq3965se 104 7 analysis analysis NN cord-292657-gq3965se 104 8 , , , cord-292657-gq3965se 104 9 it -PRON- PRP cord-292657-gq3965se 104 10 has have VBZ cord-292657-gq3965se 104 11 been be VBN cord-292657-gq3965se 104 12 observed observe VBN cord-292657-gq3965se 104 13 that that IN cord-292657-gq3965se 104 14 mutation mutation NN cord-292657-gq3965se 104 15 of of IN cord-292657-gq3965se 104 16 the the DT cord-292657-gq3965se 104 17 viral viral JJ cord-292657-gq3965se 104 18 genome genome NN cord-292657-gq3965se 104 19 and and CC cord-292657-gq3965se 104 20 genetic genetic JJ cord-292657-gq3965se 104 21 recombination recombination NN cord-292657-gq3965se 104 22 is be VBZ cord-292657-gq3965se 104 23 another another DT cord-292657-gq3965se 104 24 process process NN cord-292657-gq3965se 104 25 which which WDT cord-292657-gq3965se 104 26 confirms confirm VBZ cord-292657-gq3965se 104 27 the the DT cord-292657-gq3965se 104 28 molecular molecular JJ cord-292657-gq3965se 104 29 genetic genetic JJ cord-292657-gq3965se 104 30 variability variability NN cord-292657-gq3965se 104 31 of of IN cord-292657-gq3965se 104 32 the the DT cord-292657-gq3965se 104 33 pathogen pathogen NN cord-292657-gq3965se 104 34 . . . cord-292657-gq3965se 105 1 Several several JJ cord-292657-gq3965se 105 2 mutation mutation NN cord-292657-gq3965se 105 3 and and CC cord-292657-gq3965se 105 4 deletion deletion NN cord-292657-gq3965se 105 5 of of IN cord-292657-gq3965se 105 6 SARS SARS NNP cord-292657-gq3965se 105 7 - - HYPH cord-292657-gq3965se 105 8 CoV-2 CoV-2 NNP cord-292657-gq3965se 105 9 genome genome NN cord-292657-gq3965se 105 10 has have VBZ cord-292657-gq3965se 105 11 been be VBN cord-292657-gq3965se 105 12 observed observe VBN cord-292657-gq3965se 105 13 from from IN cord-292657-gq3965se 105 14 different different JJ cord-292657-gq3965se 105 15 SARS SARS NNP cord-292657-gq3965se 105 16 - - HYPH cord-292657-gq3965se 105 17 CoV-2 CoV-2 NNP cord-292657-gq3965se 105 18 genome genome NN cord-292657-gq3965se 105 19 sequence sequence NN cord-292657-gq3965se 105 20 references reference NNS cord-292657-gq3965se 105 21 . . . cord-292657-gq3965se 106 1 It -PRON- PRP cord-292657-gq3965se 106 2 has have VBZ cord-292657-gq3965se 106 3 been be VBN cord-292657-gq3965se 106 4 observed observe VBN cord-292657-gq3965se 106 5 that that IN cord-292657-gq3965se 106 6 mutation mutation NN cord-292657-gq3965se 106 7 has have VBZ cord-292657-gq3965se 106 8 been be VBN cord-292657-gq3965se 106 9 occurred occur VBN cord-292657-gq3965se 106 10 in in IN cord-292657-gq3965se 106 11 the the DT cord-292657-gq3965se 106 12 different different JJ cord-292657-gq3965se 106 13 structural structural JJ cord-292657-gq3965se 106 14 and and CC cord-292657-gq3965se 106 15 non non JJ cord-292657-gq3965se 106 16 - - JJ cord-292657-gq3965se 106 17 structural structural JJ cord-292657-gq3965se 106 18 glycoproteins glycoprotein NNS cord-292657-gq3965se 106 19 like like IN cord-292657-gq3965se 106 20 5 5 CD cord-292657-gq3965se 106 21 ' ' POS cord-292657-gq3965se 106 22 ORFlabpolyprotein ORFlabpolyprotein NNP cord-292657-gq3965se 106 23 , , , cord-292657-gq3965se 106 24 envelop envelop VBP cord-292657-gq3965se 106 25 protein protein NN cord-292657-gq3965se 106 26 , , , cord-292657-gq3965se 106 27 matrix matrix NN cord-292657-gq3965se 106 28 protein protein NN cord-292657-gq3965se 106 29 and and CC cord-292657-gq3965se 106 30 most most RBS cord-292657-gq3965se 106 31 important important JJ cord-292657-gq3965se 106 32 determining determine VBG cord-292657-gq3965se 106 33 factor factor NN cord-292657-gq3965se 106 34 the the DT cord-292657-gq3965se 106 35 viral viral JJ cord-292657-gq3965se 106 36 spike spike NN cord-292657-gq3965se 106 37 surface surface NN cord-292657-gq3965se 106 38 glycoprotein glycoprotein NN cord-292657-gq3965se 106 39 in in IN cord-292657-gq3965se 106 40 RBD RBD NNP cord-292657-gq3965se 106 41 domain domain NN cord-292657-gq3965se 106 42 . . . cord-292657-gq3965se 107 1 On on IN cord-292657-gq3965se 107 2 this this DT cord-292657-gq3965se 107 3 note note NN cord-292657-gq3965se 107 4 , , , cord-292657-gq3965se 107 5 no no DT cord-292657-gq3965se 107 6 such such JJ cord-292657-gq3965se 107 7 change change NN cord-292657-gq3965se 107 8 has have VBZ cord-292657-gq3965se 107 9 been be VBN cord-292657-gq3965se 107 10 observed observe VBN cord-292657-gq3965se 107 11 in in IN cord-292657-gq3965se 107 12 the the DT cord-292657-gq3965se 107 13 envelope envelope NN cord-292657-gq3965se 107 14 protein protein NN cord-292657-gq3965se 107 15 . . . cord-292657-gq3965se 108 1 Such such JJ cord-292657-gq3965se 108 2 type type NN cord-292657-gq3965se 108 3 of of IN cord-292657-gq3965se 108 4 mutation mutation NN cord-292657-gq3965se 108 5 has have VBZ cord-292657-gq3965se 108 6 been be VBN cord-292657-gq3965se 108 7 also also RB cord-292657-gq3965se 108 8 observed observe VBN cord-292657-gq3965se 108 9 in in IN cord-292657-gq3965se 108 10 betacorona betacorona NN cord-292657-gq3965se 108 11 viruses virus NNS cord-292657-gq3965se 108 12 . . . cord-292657-gq3965se 109 1 Not not RB cord-292657-gq3965se 109 2 only only RB cord-292657-gq3965se 109 3 genetic genetic JJ cord-292657-gq3965se 109 4 mutation mutation NN cord-292657-gq3965se 109 5 or or CC cord-292657-gq3965se 109 6 deletion deletion NN cord-292657-gq3965se 109 7 , , , cord-292657-gq3965se 109 8 events event NNS cord-292657-gq3965se 109 9 of of IN cord-292657-gq3965se 109 10 genetic genetic JJ cord-292657-gq3965se 109 11 recombination recombination NN cord-292657-gq3965se 109 12 has have VBZ cord-292657-gq3965se 109 13 been be VBN cord-292657-gq3965se 109 14 observed observe VBN cord-292657-gq3965se 109 15 in in IN cord-292657-gq3965se 109 16 case case NN cord-292657-gq3965se 109 17 of of IN cord-292657-gq3965se 109 18 origin origin NN cord-292657-gq3965se 109 19 of of IN cord-292657-gq3965se 109 20 SARS SARS NNP cord-292657-gq3965se 109 21 - - HYPH cord-292657-gq3965se 109 22 CoV-2 CoV-2 NNP cord-292657-gq3965se 109 23 spike spike NN cord-292657-gq3965se 109 24 protein protein NN cord-292657-gq3965se 109 25 RBD RBD NNP cord-292657-gq3965se 109 26 . . . cord-292657-gq3965se 110 1 Genetic genetic JJ cord-292657-gq3965se 110 2 recombination recombination NN cord-292657-gq3965se 110 3 events event NNS cord-292657-gq3965se 110 4 among among IN cord-292657-gq3965se 110 5 bat bat NN cord-292657-gq3965se 110 6 , , , cord-292657-gq3965se 110 7 pangolin pangolin NN cord-292657-gq3965se 110 8 and and CC cord-292657-gq3965se 110 9 human human NNP cord-292657-gq3965se 110 10 corona corona NNP cord-292657-gq3965se 110 11 virus virus NN cord-292657-gq3965se 110 12 confirms confirm VBZ cord-292657-gq3965se 110 13 this this DT cord-292657-gq3965se 110 14 [ [ -LRB- cord-292657-gq3965se 110 15 16 16 CD cord-292657-gq3965se 110 16 , , , cord-292657-gq3965se 110 17 21 21 CD cord-292657-gq3965se 110 18 , , , cord-292657-gq3965se 110 19 26 26 CD cord-292657-gq3965se 110 20 ] ] -RRB- cord-292657-gq3965se 110 21 . . . cord-292657-gq3965se 111 1 So so CC cord-292657-gq3965se 111 2 it -PRON- PRP cord-292657-gq3965se 111 3 is be VBZ cord-292657-gq3965se 111 4 clear clear JJ cord-292657-gq3965se 111 5 from from IN cord-292657-gq3965se 111 6 the the DT cord-292657-gq3965se 111 7 above above JJ cord-292657-gq3965se 111 8 study study NN cord-292657-gq3965se 111 9 that that IN cord-292657-gq3965se 111 10 , , , cord-292657-gq3965se 111 11 generation generation NN cord-292657-gq3965se 111 12 of of IN cord-292657-gq3965se 111 13 new new JJ cord-292657-gq3965se 111 14 versions version NNS cord-292657-gq3965se 111 15 of of IN cord-292657-gq3965se 111 16 viral viral JJ cord-292657-gq3965se 111 17 diseases disease NNS cord-292657-gq3965se 111 18 in in IN cord-292657-gq3965se 111 19 humans human NNS cord-292657-gq3965se 111 20 is be VBZ cord-292657-gq3965se 111 21 acquired acquire VBN cord-292657-gq3965se 111 22 due due IN cord-292657-gq3965se 111 23 to to IN cord-292657-gq3965se 111 24 the the DT cord-292657-gq3965se 111 25 continuous continuous JJ cord-292657-gq3965se 111 26 molecular molecular JJ cord-292657-gq3965se 111 27 genetic genetic JJ cord-292657-gq3965se 111 28 operations operation NNS cord-292657-gq3965se 111 29 inside inside IN cord-292657-gq3965se 111 30 host host NN cord-292657-gq3965se 111 31 body body NN cord-292657-gq3965se 111 32 by by IN cord-292657-gq3965se 111 33 continuous continuous JJ cord-292657-gq3965se 111 34 species specie NNS cord-292657-gq3965se 111 35 transmission transmission NN cord-292657-gq3965se 111 36 . . . cord-292657-gq3965se 112 1 This this DT cord-292657-gq3965se 112 2 event event NN cord-292657-gq3965se 112 3 can can MD cord-292657-gq3965se 112 4 be be VB cord-292657-gq3965se 112 5 supported support VBN cord-292657-gq3965se 112 6 by by IN cord-292657-gq3965se 112 7 the the DT cord-292657-gq3965se 112 8 evidence evidence NN cord-292657-gq3965se 112 9 of of IN cord-292657-gq3965se 112 10 acquisition acquisition NN cord-292657-gq3965se 112 11 of of IN cord-292657-gq3965se 112 12 adapted adapt VBN cord-292657-gq3965se 112 13 character character NN cord-292657-gq3965se 112 14 during during IN cord-292657-gq3965se 112 15 repeated repeat VBN cord-292657-gq3965se 112 16 cell cell NN cord-292657-gq3965se 112 17 culture culture NN cord-292657-gq3965se 112 18 passagingof passagingof NN cord-292657-gq3965se 112 19 the the DT cord-292657-gq3965se 112 20 SARS SARS NNP cord-292657-gq3965se 112 21 - - HYPH cord-292657-gq3965se 112 22 CoV CoV NNP cord-292657-gq3965se 112 23 [ [ -LRB- cord-292657-gq3965se 112 24 23 23 CD cord-292657-gq3965se 112 25 ] ] -RRB- cord-292657-gq3965se 112 26 . . . cord-292657-gq3965se 113 1 But but CC cord-292657-gq3965se 113 2 on on IN cord-292657-gq3965se 113 3 this this DT cord-292657-gq3965se 113 4 note note NN cord-292657-gq3965se 113 5 it -PRON- PRP cord-292657-gq3965se 113 6 should should MD cord-292657-gq3965se 113 7 be be VB cord-292657-gq3965se 113 8 pointed point VBN cord-292657-gq3965se 113 9 that that IN cord-292657-gq3965se 113 10 , , , cord-292657-gq3965se 113 11 new new JJ cord-292657-gq3965se 113 12 disease disease NN cord-292657-gq3965se 113 13 may may MD cord-292657-gq3965se 113 14 appear appear VB cord-292657-gq3965se 113 15 at at IN cord-292657-gq3965se 113 16 any any DT cord-292657-gq3965se 113 17 time time NN cord-292657-gq3965se 113 18 , , , cord-292657-gq3965se 113 19 in in IN cord-292657-gq3965se 113 20 any any DT cord-292657-gq3965se 113 21 places place NNS cord-292657-gq3965se 113 22 , , , cord-292657-gq3965se 113 23 among among IN cord-292657-gq3965se 113 24 any any DT cord-292657-gq3965se 113 25 population population NN cord-292657-gq3965se 113 26 which which WDT cord-292657-gq3965se 113 27 is be VBZ cord-292657-gq3965se 113 28 unpredictable unpredictable JJ cord-292657-gq3965se 113 29 , , , cord-292657-gq3965se 113 30 because because IN cord-292657-gq3965se 113 31 evolution evolution NN cord-292657-gq3965se 113 32 is be VBZ cord-292657-gq3965se 113 33 a a DT cord-292657-gq3965se 113 34 collective collective JJ cord-292657-gq3965se 113 35 action action NN cord-292657-gq3965se 113 36 of of IN cord-292657-gq3965se 113 37 genetic genetic JJ cord-292657-gq3965se 113 38 operation operation NN cord-292657-gq3965se 113 39 and and CC cord-292657-gq3965se 113 40 environmental environmental JJ cord-292657-gq3965se 113 41 effect effect NN cord-292657-gq3965se 113 42 . . . cord-292657-gq3965se 114 1 In in IN cord-292657-gq3965se 114 2 case case NN cord-292657-gq3965se 114 3 of of IN cord-292657-gq3965se 114 4 virus virus NN cord-292657-gq3965se 114 5 the the DT cord-292657-gq3965se 114 6 host host NN cord-292657-gq3965se 114 7 body body NN cord-292657-gq3965se 114 8 is be VBZ cord-292657-gq3965se 114 9 the the DT cord-292657-gq3965se 114 10 key key JJ cord-292657-gq3965se 114 11 factor factor NN cord-292657-gq3965se 114 12 which which WDT cord-292657-gq3965se 114 13 actually actually RB cord-292657-gq3965se 114 14 gives give VBZ cord-292657-gq3965se 114 15 this this DT cord-292657-gq3965se 114 16 opportunity opportunity NN cord-292657-gq3965se 114 17 or or CC cord-292657-gq3965se 114 18 favorable favorable JJ cord-292657-gq3965se 114 19 environment environment NN cord-292657-gq3965se 114 20 for for IN cord-292657-gq3965se 114 21 these these DT cord-292657-gq3965se 114 22 genetic genetic JJ cord-292657-gq3965se 114 23 operations operation NNS cord-292657-gq3965se 114 24 to to TO cord-292657-gq3965se 114 25 happen happen VB cord-292657-gq3965se 114 26 because because IN cord-292657-gq3965se 114 27 the the DT cord-292657-gq3965se 114 28 virus virus NN cord-292657-gq3965se 114 29 needs need VBZ cord-292657-gq3965se 114 30 a a DT cord-292657-gq3965se 114 31 host host NN cord-292657-gq3965se 114 32 body body NN cord-292657-gq3965se 114 33 as as IN cord-292657-gq3965se 114 34 a a DT cord-292657-gq3965se 114 35 resource resource NN cord-292657-gq3965se 114 36 to to TO cord-292657-gq3965se 114 37 be be VB cord-292657-gq3965se 114 38 functionally functionally RB cord-292657-gq3965se 114 39 active active JJ cord-292657-gq3965se 114 40 . . . cord-292657-gq3965se 115 1 It -PRON- PRP cord-292657-gq3965se 115 2 is be VBZ cord-292657-gq3965se 115 3 the the DT cord-292657-gq3965se 115 4 normal normal JJ cord-292657-gq3965se 115 5 tendency tendency NN cord-292657-gq3965se 115 6 of of IN cord-292657-gq3965se 115 7 a a DT cord-292657-gq3965se 115 8 microbial microbial JJ cord-292657-gq3965se 115 9 species specie NNS cord-292657-gq3965se 115 10 to to TO cord-292657-gq3965se 115 11 find find VB cord-292657-gq3965se 115 12 a a DT cord-292657-gq3965se 115 13 convincible convincible JJ cord-292657-gq3965se 115 14 way way NN cord-292657-gq3965se 115 15 to to TO cord-292657-gq3965se 115 16 transmit transmit VB cord-292657-gq3965se 115 17 and and CC cord-292657-gq3965se 115 18 adapt adapt VB cord-292657-gq3965se 115 19 itself -PRON- PRP cord-292657-gq3965se 115 20 to to IN cord-292657-gq3965se 115 21 new new JJ cord-292657-gq3965se 115 22 environment environment NN cord-292657-gq3965se 115 23 for for IN cord-292657-gq3965se 115 24 evolution evolution NN cord-292657-gq3965se 115 25 . . . cord-292657-gq3965se 116 1 In in IN cord-292657-gq3965se 116 2 case case NN cord-292657-gq3965se 116 3 of of IN cord-292657-gq3965se 116 4 virus virus NN cord-292657-gq3965se 116 5 , , , cord-292657-gq3965se 116 6 more more RBR cord-292657-gq3965se 116 7 specifically specifically RB cord-292657-gq3965se 116 8 for for IN cord-292657-gq3965se 116 9 the the DT cord-292657-gq3965se 116 10 RNA RNA NNP cord-292657-gq3965se 116 11 virus virus NN cord-292657-gq3965se 116 12 , , , cord-292657-gq3965se 116 13 the the DT cord-292657-gq3965se 116 14 tendency tendency NN cord-292657-gq3965se 116 15 is be VBZ cord-292657-gq3965se 116 16 high high JJ cord-292657-gq3965se 116 17 where where WRB cord-292657-gq3965se 116 18 there there EX cord-292657-gq3965se 116 19 is be VBZ cord-292657-gq3965se 116 20 continuous continuous JJ cord-292657-gq3965se 116 21 circulation circulation NN cord-292657-gq3965se 116 22 of of IN cord-292657-gq3965se 116 23 the the DT cord-292657-gq3965se 116 24 viral viral JJ cord-292657-gq3965se 116 25 genome genome NN cord-292657-gq3965se 116 26 among among IN cord-292657-gq3965se 116 27 different different JJ cord-292657-gq3965se 116 28 host host NN cord-292657-gq3965se 116 29 species specie NNS cord-292657-gq3965se 116 30 [ [ -LRB- cord-292657-gq3965se 116 31 28 28 CD cord-292657-gq3965se 116 32 ] ] -RRB- cord-292657-gq3965se 116 33 . . . cord-292657-gq3965se 117 1 During during IN cord-292657-gq3965se 117 2 this this DT cord-292657-gq3965se 117 3 period period NN cord-292657-gq3965se 117 4 , , , cord-292657-gq3965se 117 5 host host NN cord-292657-gq3965se 117 6 environment environment NN cord-292657-gq3965se 117 7 creates create VBZ cord-292657-gq3965se 117 8 intense intense JJ cord-292657-gq3965se 117 9 selective selective JJ cord-292657-gq3965se 117 10 pressure pressure NN cord-292657-gq3965se 117 11 to to IN cord-292657-gq3965se 117 12 the the DT cord-292657-gq3965se 117 13 pathogen pathogen NN cord-292657-gq3965se 117 14 . . . cord-292657-gq3965se 118 1 The the DT cord-292657-gq3965se 118 2 host host NN cord-292657-gq3965se 118 3 body body NN cord-292657-gq3965se 118 4 environment environment NN cord-292657-gq3965se 118 5 is be VBZ cord-292657-gq3965se 118 6 acting act VBG cord-292657-gq3965se 118 7 as as IN cord-292657-gq3965se 118 8 an an DT cord-292657-gq3965se 118 9 influential influential JJ cord-292657-gq3965se 118 10 factor factor NN cord-292657-gq3965se 118 11 for for IN cord-292657-gq3965se 118 12 the the DT cord-292657-gq3965se 118 13 virus virus NN cord-292657-gq3965se 118 14 to to TO cord-292657-gq3965se 118 15 take take VB cord-292657-gq3965se 118 16 a a DT cord-292657-gq3965se 118 17 do do NN cord-292657-gq3965se 118 18 or or CC cord-292657-gq3965se 118 19 die die VB cord-292657-gq3965se 118 20 decission decission NN cord-292657-gq3965se 118 21 . . . cord-292657-gq3965se 119 1 When when WRB cord-292657-gq3965se 119 2 the the DT cord-292657-gq3965se 119 3 virusis virusis NN cord-292657-gq3965se 119 4 successful successful JJ cord-292657-gq3965se 119 5 , , , cord-292657-gq3965se 119 6 it -PRON- PRP cord-292657-gq3965se 119 7 is be VBZ cord-292657-gq3965se 119 8 naturally naturally RB cord-292657-gq3965se 119 9 selected select VBN cord-292657-gq3965se 119 10 and and CC cord-292657-gq3965se 119 11 adapted adapt VBN cord-292657-gq3965se 119 12 to to TO cord-292657-gq3965se 119 13 establish establish VB cord-292657-gq3965se 119 14 its -PRON- PRP$ cord-292657-gq3965se 119 15 character character NN cord-292657-gq3965se 119 16 by by IN cord-292657-gq3965se 119 17 gettingthe gettingthe NNP cord-292657-gq3965se 119 18 control control NN cord-292657-gq3965se 119 19 over over IN cord-292657-gq3965se 119 20 the the DT cord-292657-gq3965se 119 21 host host NN cord-292657-gq3965se 119 22 's 's POS cord-292657-gq3965se 119 23 genetic genetic JJ cord-292657-gq3965se 119 24 construction construction NN cord-292657-gq3965se 119 25 by by IN cord-292657-gq3965se 119 26 exerting exert VBG cord-292657-gq3965se 119 27 virulent virulent JJ cord-292657-gq3965se 119 28 effects effect NNS cord-292657-gq3965se 119 29 . . . cord-292657-gq3965se 120 1 When when WRB cord-292657-gq3965se 120 2 this this DT cord-292657-gq3965se 120 3 process process NN cord-292657-gq3965se 120 4 continuously continuously RB cord-292657-gq3965se 120 5 goes go VBZ cord-292657-gq3965se 120 6 on on RP cord-292657-gq3965se 120 7 by by IN cord-292657-gq3965se 120 8 exposure exposure NN cord-292657-gq3965se 120 9 to to IN cord-292657-gq3965se 120 10 new new JJ cord-292657-gq3965se 120 11 environments environment NNS cord-292657-gq3965se 120 12 , , , cord-292657-gq3965se 120 13 it -PRON- PRP cord-292657-gq3965se 120 14 can can MD cord-292657-gq3965se 120 15 lead lead VB cord-292657-gq3965se 120 16 to to IN cord-292657-gq3965se 120 17 an an DT cord-292657-gq3965se 120 18 extent extent NN cord-292657-gq3965se 120 19 where where WRB cord-292657-gq3965se 120 20 it -PRON- PRP cord-292657-gq3965se 120 21 can can MD cord-292657-gq3965se 120 22 cause cause VB cord-292657-gq3965se 120 23 a a DT cord-292657-gq3965se 120 24 pandemic pandemic NN cord-292657-gq3965se 120 25 , , , cord-292657-gq3965se 120 26 otherwise otherwise RB cord-292657-gq3965se 120 27 it -PRON- PRP cord-292657-gq3965se 120 28 is be VBZ cord-292657-gq3965se 120 29 the the DT cord-292657-gq3965se 120 30 end end NN cord-292657-gq3965se 120 31 of of IN cord-292657-gq3965se 120 32 line line NN cord-292657-gq3965se 120 33 for for IN cord-292657-gq3965se 120 34 the the DT cord-292657-gq3965se 120 35 pathogen pathogen NN cord-292657-gq3965se 120 36 to to TO cord-292657-gq3965se 120 37 evolve evolve VB cord-292657-gq3965se 120 38 . . . cord-292657-gq3965se 121 1 This this DT cord-292657-gq3965se 121 2 is be VBZ cord-292657-gq3965se 121 3 a a DT cord-292657-gq3965se 121 4 gradual gradual JJ cord-292657-gq3965se 121 5 process process NN cord-292657-gq3965se 121 6 , , , cord-292657-gq3965se 121 7 when when WRB cord-292657-gq3965se 121 8 the the DT cord-292657-gq3965se 121 9 virus virus NN cord-292657-gq3965se 121 10 accumulate accumulate VBP cord-292657-gq3965se 121 11 the the DT cord-292657-gq3965se 121 12 required require VBN cord-292657-gq3965se 121 13 genetic genetic JJ cord-292657-gq3965se 121 14 makeup makeup NN cord-292657-gq3965se 121 15 or or CC cord-292657-gq3965se 121 16 prepare prepare VB cord-292657-gq3965se 121 17 itself -PRON- PRP cord-292657-gq3965se 121 18 and and CC cord-292657-gq3965se 121 19 takes take VBZ cord-292657-gq3965se 121 20 several several JJ cord-292657-gq3965se 121 21 attempt attempt NN cord-292657-gq3965se 121 22 for for IN cord-292657-gq3965se 121 23 the the DT cord-292657-gq3965se 121 24 big big JJ cord-292657-gq3965se 121 25 jump jump NN cord-292657-gq3965se 121 26 . . . cord-292657-gq3965se 122 1 During during IN cord-292657-gq3965se 122 2 this this DT cord-292657-gq3965se 122 3 preparatory preparatory JJ cord-292657-gq3965se 122 4 phase phase NN cord-292657-gq3965se 122 5 the the DT cord-292657-gq3965se 122 6 pathogen pathogen NN cord-292657-gq3965se 122 7 can can MD cord-292657-gq3965se 122 8 generate generate VB cord-292657-gq3965se 122 9 mild mild JJ cord-292657-gq3965se 122 10 infection infection NN cord-292657-gq3965se 122 11 or or CC cord-292657-gq3965se 122 12 infection infection NN cord-292657-gq3965se 122 13 to to IN cord-292657-gq3965se 122 14 a a DT cord-292657-gq3965se 122 15 limited limited JJ cord-292657-gq3965se 122 16 bunch bunch NN cord-292657-gq3965se 122 17 of of IN cord-292657-gq3965se 122 18 population population NN cord-292657-gq3965se 122 19 or or CC cord-292657-gq3965se 122 20 create create VB cord-292657-gq3965se 122 21 silent silent JJ cord-292657-gq3965se 122 22 carriers carrier NNS cord-292657-gq3965se 122 23 depending depend VBG cord-292657-gq3965se 122 24 on on IN cord-292657-gq3965se 122 25 the the DT cord-292657-gq3965se 122 26 host host NN cord-292657-gq3965se 122 27 body body NN cord-292657-gq3965se 122 28 environment environment NN cord-292657-gq3965se 122 29 . . . cord-292657-gq3965se 123 1 These these DT cord-292657-gq3965se 123 2 carriers carrier NNS cord-292657-gq3965se 123 3 do do VBP cord-292657-gq3965se 123 4 n't not RB cord-292657-gq3965se 123 5 show show VB cord-292657-gq3965se 123 6 any any DT cord-292657-gq3965se 123 7 symptoms symptom NNS cord-292657-gq3965se 123 8 but but CC cord-292657-gq3965se 123 9 the the DT cord-292657-gq3965se 123 10 infectious infectious JJ cord-292657-gq3965se 123 11 pathogen pathogen NN cord-292657-gq3965se 123 12 with with IN cord-292657-gq3965se 123 13 its -PRON- PRP$ cord-292657-gq3965se 123 14 new new JJ cord-292657-gq3965se 123 15 genetic genetic JJ cord-292657-gq3965se 123 16 makeup makeup NN cord-292657-gq3965se 123 17 is be VBZ cord-292657-gq3965se 123 18 maintained maintain VBN cord-292657-gq3965se 123 19 here here RB cord-292657-gq3965se 123 20 and and CC cord-292657-gq3965se 123 21 can can MD cord-292657-gq3965se 123 22 be be VB cord-292657-gq3965se 123 23 transmitted transmit VBN cord-292657-gq3965se 123 24 to to IN cord-292657-gq3965se 123 25 different different JJ cord-292657-gq3965se 123 26 suitable suitable JJ cord-292657-gq3965se 123 27 host host NN cord-292657-gq3965se 123 28 environment environment NN cord-292657-gq3965se 123 29 for for IN cord-292657-gq3965se 123 30 disease disease NN cord-292657-gq3965se 123 31 establishment establishment NN cord-292657-gq3965se 123 32 . . . cord-292657-gq3965se 124 1 Thus thus RB cord-292657-gq3965se 124 2 these these DT cord-292657-gq3965se 124 3 carriers carrier NNS cord-292657-gq3965se 124 4 are be VBP cord-292657-gq3965se 124 5 very very RB cord-292657-gq3965se 124 6 crucial crucial JJ cord-292657-gq3965se 124 7 , , , cord-292657-gq3965se 124 8 and and CC cord-292657-gq3965se 124 9 might may MD cord-292657-gq3965se 124 10 be be VB cord-292657-gq3965se 124 11 another another DT cord-292657-gq3965se 124 12 strategy strategy NN cord-292657-gq3965se 124 13 of of IN cord-292657-gq3965se 124 14 the the DT cord-292657-gq3965se 124 15 virus virus NN cord-292657-gq3965se 124 16 for for IN cord-292657-gq3965se 124 17 the the DT cord-292657-gq3965se 124 18 evolution evolution NN cord-292657-gq3965se 124 19 of of IN cord-292657-gq3965se 124 20 new new JJ cord-292657-gq3965se 124 21 genetic genetic JJ cord-292657-gq3965se 124 22 setup setup NN cord-292657-gq3965se 124 23 . . . cord-292657-gq3965se 125 1 An an DT cord-292657-gq3965se 125 2 evolved evolved JJ cord-292657-gq3965se 125 3 character character NN cord-292657-gq3965se 125 4 is be VBZ cord-292657-gq3965se 125 5 developed develop VBN cord-292657-gq3965se 125 6 under under IN cord-292657-gq3965se 125 7 environmental environmental JJ cord-292657-gq3965se 125 8 pressure pressure NN cord-292657-gq3965se 125 9 [ [ -LRB- cord-292657-gq3965se 125 10 25 25 CD cord-292657-gq3965se 125 11 ] ] -RRB- cord-292657-gq3965se 125 12 . . . cord-292657-gq3965se 126 1 In in IN cord-292657-gq3965se 126 2 this this DT cord-292657-gq3965se 126 3 case case NN cord-292657-gq3965se 126 4 , , , cord-292657-gq3965se 126 5 the the DT cord-292657-gq3965se 126 6 protective protective JJ cord-292657-gq3965se 126 7 immune immune JJ cord-292657-gq3965se 126 8 system system NN cord-292657-gq3965se 126 9 of of IN cord-292657-gq3965se 126 10 the the DT cord-292657-gq3965se 126 11 host host NN cord-292657-gq3965se 126 12 body body NN cord-292657-gq3965se 126 13 environment environment NN cord-292657-gq3965se 126 14 helps help VBZ cord-292657-gq3965se 126 15 the the DT cord-292657-gq3965se 126 16 virus virus NN cord-292657-gq3965se 126 17 to to TO cord-292657-gq3965se 126 18 evolve evolve VB cord-292657-gq3965se 126 19 under under IN cord-292657-gq3965se 126 20 selective selective JJ cord-292657-gq3965se 126 21 pressure pressure NN cord-292657-gq3965se 126 22 of of IN cord-292657-gq3965se 126 23 infection infection NN cord-292657-gq3965se 126 24 rejection rejection NN cord-292657-gq3965se 126 25 . . . cord-292657-gq3965se 127 1 Identification identification NN cord-292657-gq3965se 127 2 of of IN cord-292657-gq3965se 127 3 several several JJ cord-292657-gq3965se 127 4 asymptomatic asymptomatic JJ cord-292657-gq3965se 127 5 carriers carrier NNS cord-292657-gq3965se 127 6 for for IN cord-292657-gq3965se 127 7 SARS SARS NNP cord-292657-gq3965se 127 8 - - HYPH cord-292657-gq3965se 127 9 CoV-2 CoV-2 NNP cord-292657-gq3965se 127 10 can can MD cord-292657-gq3965se 127 11 be be VB cord-292657-gq3965se 127 12 a a DT cord-292657-gq3965se 127 13 result result NN cord-292657-gq3965se 127 14 of of IN cord-292657-gq3965se 127 15 the the DT cord-292657-gq3965se 127 16 above above JJ cord-292657-gq3965se 127 17 fact fact NN cord-292657-gq3965se 127 18 . . . cord-292657-gq3965se 128 1 Thus thus RB cord-292657-gq3965se 128 2 virus virus NN cord-292657-gq3965se 128 3 is be VBZ cord-292657-gq3965se 128 4 the the DT cord-292657-gq3965se 128 5 player player NN cord-292657-gq3965se 128 6 , , , cord-292657-gq3965se 128 7 but but CC cord-292657-gq3965se 128 8 its -PRON- PRP$ cord-292657-gq3965se 128 9 ' ' `` cord-292657-gq3965se 128 10 optimum optimum JJ cord-292657-gq3965se 128 11 molecular molecular JJ cord-292657-gq3965se 128 12 genetic genetic JJ cord-292657-gq3965se 128 13 fitness fitness NN cord-292657-gq3965se 128 14 , , , cord-292657-gq3965se 128 15 distribution distribution NN cord-292657-gq3965se 128 16 and and CC cord-292657-gq3965se 128 17 evolution evolution NN cord-292657-gq3965se 128 18 are be VBP cord-292657-gq3965se 128 19 shaped shape VBN cord-292657-gq3965se 128 20 by by IN cord-292657-gq3965se 128 21 the the DT cord-292657-gq3965se 128 22 host host NN cord-292657-gq3965se 128 23 body body NN cord-292657-gq3965se 128 24 environment environment NN cord-292657-gq3965se 128 25 [ [ -LRB- cord-292657-gq3965se 128 26 12 12 CD cord-292657-gq3965se 128 27 , , , cord-292657-gq3965se 128 28 19 19 CD cord-292657-gq3965se 128 29 , , , cord-292657-gq3965se 128 30 24 24 CD cord-292657-gq3965se 128 31 ] ] -RRB- cord-292657-gq3965se 128 32 . . . cord-292657-gq3965se 129 1 In in IN cord-292657-gq3965se 129 2 case case NN cord-292657-gq3965se 129 3 of of IN cord-292657-gq3965se 129 4 SARS SARS NNP cord-292657-gq3965se 129 5 - - HYPH cord-292657-gq3965se 129 6 CoV-2 CoV-2 NNP cord-292657-gq3965se 129 7 its -PRON- PRP$ cord-292657-gq3965se 129 8 diverse diverse JJ cord-292657-gq3965se 129 9 genetic genetic JJ cord-292657-gq3965se 129 10 variability variability NN cord-292657-gq3965se 129 11 and and CC cord-292657-gq3965se 129 12 evidence evidence NN cord-292657-gq3965se 129 13 of of IN cord-292657-gq3965se 129 14 its -PRON- PRP$ cord-292657-gq3965se 129 15 existence existence NN cord-292657-gq3965se 129 16 among among IN cord-292657-gq3965se 129 17 different different JJ cord-292657-gq3965se 129 18 host host NN cord-292657-gq3965se 129 19 species specie NNS cord-292657-gq3965se 129 20 indicates indicate VBZ cord-292657-gq3965se 129 21 towards towards IN cord-292657-gq3965se 129 22 its -PRON- PRP$ cord-292657-gq3965se 129 23 rapid rapid JJ cord-292657-gq3965se 129 24 ' ' '' cord-292657-gq3965se 129 25 ' ' '' cord-292657-gq3965se 129 26 jumping jump VBG cord-292657-gq3965se 129 27 species specie NNS cord-292657-gq3965se 129 28 ' ' '' cord-292657-gq3965se 129 29 ' ' '' cord-292657-gq3965se 129 30 nature nature NN cord-292657-gq3965se 129 31 which which WDT cord-292657-gq3965se 129 32 probably probably RB cord-292657-gq3965se 129 33 makes make VBZ cord-292657-gq3965se 129 34 it -PRON- PRP cord-292657-gq3965se 129 35 extremely extremely RB cord-292657-gq3965se 129 36 diverse diverse JJ cord-292657-gq3965se 129 37 and and CC cord-292657-gq3965se 129 38 virulent virulent JJ cord-292657-gq3965se 129 39 . . . cord-292657-gq3965se 130 1 The the DT cord-292657-gq3965se 130 2 host host NN cord-292657-gq3965se 130 3 body body NN cord-292657-gq3965se 130 4 environment environment NN cord-292657-gq3965se 130 5 gave give VBD cord-292657-gq3965se 130 6 the the DT cord-292657-gq3965se 130 7 virus virus NN cord-292657-gq3965se 130 8 the the DT cord-292657-gq3965se 130 9 opportunity opportunity NN cord-292657-gq3965se 130 10 to to TO cord-292657-gq3965se 130 11 prepare prepare VB cord-292657-gq3965se 130 12 for for IN cord-292657-gq3965se 130 13 the the DT cord-292657-gq3965se 130 14 battle battle NN cord-292657-gq3965se 130 15 where where WRB cord-292657-gq3965se 130 16 both both CC cord-292657-gq3965se 130 17 the the DT cord-292657-gq3965se 130 18 genetic genetic JJ cord-292657-gq3965se 130 19 manipulation manipulation NN cord-292657-gq3965se 130 20 and and CC cord-292657-gq3965se 130 21 the the DT cord-292657-gq3965se 130 22 natural natural JJ cord-292657-gq3965se 130 23 selection selection NN cord-292657-gq3965se 130 24 process process NN cord-292657-gq3965se 130 25 plays play VBZ cord-292657-gq3965se 130 26 major major JJ cord-292657-gq3965se 130 27 role role NN cord-292657-gq3965se 130 28 for for IN cord-292657-gq3965se 130 29 its -PRON- PRP$ cord-292657-gq3965se 130 30 adaptability adaptability NN cord-292657-gq3965se 130 31 resulting result VBG cord-292657-gq3965se 130 32 the the DT cord-292657-gq3965se 130 33 current current JJ cord-292657-gq3965se 130 34 uncontrolled uncontrolled JJ cord-292657-gq3965se 130 35 pandemic pandemic NN cord-292657-gq3965se 130 36 . . . cord-292657-gq3965se 131 1 From from IN cord-292657-gq3965se 131 2 another another DT cord-292657-gq3965se 131 3 angle angle NN cord-292657-gq3965se 131 4 if if IN cord-292657-gq3965se 131 5 we -PRON- PRP cord-292657-gq3965se 131 6 look look VBP cord-292657-gq3965se 131 7 over over IN cord-292657-gq3965se 131 8 the the DT cord-292657-gq3965se 131 9 two two CD cord-292657-gq3965se 131 10 extremities extremity NNS cord-292657-gq3965se 131 11 of of IN cord-292657-gq3965se 131 12 the the DT cord-292657-gq3965se 131 13 origin origin NN cord-292657-gq3965se 131 14 and and CC cord-292657-gq3965se 131 15 exposure exposure NN cord-292657-gq3965se 131 16 of of IN cord-292657-gq3965se 131 17 the the DT cord-292657-gq3965se 131 18 SARS SARS NNP cord-292657-gq3965se 131 19 - - HYPH cord-292657-gq3965se 131 20 CoV-2 CoV-2 NNP cord-292657-gq3965se 131 21 , , , cord-292657-gq3965se 131 22 they -PRON- PRP cord-292657-gq3965se 131 23 are be VBP cord-292657-gq3965se 131 24 bats bat NNS cord-292657-gq3965se 131 25 and and CC cord-292657-gq3965se 131 26 humans human NNS cord-292657-gq3965se 131 27 . . . cord-292657-gq3965se 132 1 Both both DT cord-292657-gq3965se 132 2 of of IN cord-292657-gq3965se 132 3 the the DT cord-292657-gq3965se 132 4 host host NN cord-292657-gq3965se 132 5 environments environment NNS cord-292657-gq3965se 132 6 can can MD cord-292657-gq3965se 132 7 be be VB cord-292657-gq3965se 132 8 considered consider VBN cord-292657-gq3965se 132 9 as as IN cord-292657-gq3965se 132 10 large large JJ cord-292657-gq3965se 132 11 population population NN cord-292657-gq3965se 132 12 . . . cord-292657-gq3965se 133 1 Bats bat NNS cord-292657-gq3965se 133 2 is be VBZ cord-292657-gq3965se 133 3 the the DT cord-292657-gq3965se 133 4 reservoir reservoir NN cord-292657-gq3965se 133 5 of of IN cord-292657-gq3965se 133 6 a a DT cord-292657-gq3965se 133 7 large large JJ cord-292657-gq3965se 133 8 number number NN cord-292657-gq3965se 133 9 of of IN cord-292657-gq3965se 133 10 viral viral JJ cord-292657-gq3965se 133 11 pathogens pathogen NNS cord-292657-gq3965se 133 12 and and CC cord-292657-gq3965se 133 13 inhabit inhabit VBP cord-292657-gq3965se 133 14 in in IN cord-292657-gq3965se 133 15 a a DT cord-292657-gq3965se 133 16 giggling giggle VBG cord-292657-gq3965se 133 17 manner manner NN cord-292657-gq3965se 133 18 in in IN cord-292657-gq3965se 133 19 a a DT cord-292657-gq3965se 133 20 close close JJ cord-292657-gq3965se 133 21 contact contact NN cord-292657-gq3965se 133 22 thus thus RB cord-292657-gq3965se 133 23 enhances enhance VBZ cord-292657-gq3965se 133 24 the the DT cord-292657-gq3965se 133 25 chance chance NN cord-292657-gq3965se 133 26 of of IN cord-292657-gq3965se 133 27 cross cross NN cord-292657-gq3965se 133 28 transmission transmission NN cord-292657-gq3965se 133 29 and and CC cord-292657-gq3965se 133 30 giving give VBG cord-292657-gq3965se 133 31 the the DT cord-292657-gq3965se 133 32 pathogen pathogen NN cord-292657-gq3965se 133 33 a a DT cord-292657-gq3965se 133 34 field field NN cord-292657-gq3965se 133 35 to to TO cord-292657-gq3965se 133 36 evolve evolve VB cord-292657-gq3965se 133 37 . . . cord-292657-gq3965se 134 1 Similarly similarly RB cord-292657-gq3965se 134 2 , , , cord-292657-gq3965se 134 3 the the DT cord-292657-gq3965se 134 4 modern modern JJ cord-292657-gq3965se 134 5 human human JJ cord-292657-gq3965se 134 6 population population NN cord-292657-gq3965se 134 7 is be VBZ cord-292657-gq3965se 134 8 highly highly RB cord-292657-gq3965se 134 9 dynamic dynamic JJ cord-292657-gq3965se 134 10 and and CC cord-292657-gq3965se 134 11 exposed expose VBN cord-292657-gq3965se 134 12 to to IN cord-292657-gq3965se 134 13 various various JJ cord-292657-gq3965se 134 14 extreme extreme JJ cord-292657-gq3965se 134 15 environmental environmental JJ cord-292657-gq3965se 134 16 conditions condition NNS cord-292657-gq3965se 134 17 . . . cord-292657-gq3965se 135 1 The the DT cord-292657-gq3965se 135 2 large large JJ cord-292657-gq3965se 135 3 co co JJ cord-292657-gq3965se 135 4 habitation habitation NN cord-292657-gq3965se 135 5 and and CC cord-292657-gq3965se 135 6 lifestyle lifestyle NN cord-292657-gq3965se 135 7 pattern pattern NN cord-292657-gq3965se 135 8 enhances enhance VBZ cord-292657-gq3965se 135 9 the the DT cord-292657-gq3965se 135 10 chance chance NN cord-292657-gq3965se 135 11 of of IN cord-292657-gq3965se 135 12 cross cross JJ cord-292657-gq3965se 135 13 transmission transmission NN cord-292657-gq3965se 135 14 of of IN cord-292657-gq3965se 135 15 virus virus NN cord-292657-gq3965se 135 16 and and CC cord-292657-gq3965se 135 17 make make VB cord-292657-gq3965se 135 18 a a DT cord-292657-gq3965se 135 19 susceptible susceptible JJ cord-292657-gq3965se 135 20 environment environment NN cord-292657-gq3965se 135 21 for for IN cord-292657-gq3965se 135 22 emerging emerge VBG cord-292657-gq3965se 135 23 new new JJ cord-292657-gq3965se 135 24 viral viral JJ cord-292657-gq3965se 135 25 disease disease NN cord-292657-gq3965se 135 26 . . . cord-292657-gq3965se 136 1 After after IN cord-292657-gq3965se 136 2 considering consider VBG cord-292657-gq3965se 136 3 the the DT cord-292657-gq3965se 136 4 impact impact NN cord-292657-gq3965se 136 5 of of IN cord-292657-gq3965se 136 6 molecular molecular JJ cord-292657-gq3965se 136 7 genetic genetic JJ cord-292657-gq3965se 136 8 diversity diversity NN cord-292657-gq3965se 136 9 and and CC cord-292657-gq3965se 136 10 host host NN cord-292657-gq3965se 136 11 body body NN cord-292657-gq3965se 136 12 environment environment NN cord-292657-gq3965se 136 13 in in IN cord-292657-gq3965se 136 14 the the DT cord-292657-gq3965se 136 15 origin origin NN cord-292657-gq3965se 136 16 and and CC cord-292657-gq3965se 136 17 development development NN cord-292657-gq3965se 136 18 of of IN cord-292657-gq3965se 136 19 a a DT cord-292657-gq3965se 136 20 virulent virulent JJ cord-292657-gq3965se 136 21 strain strain NN cord-292657-gq3965se 136 22 , , , cord-292657-gq3965se 136 23 we -PRON- PRP cord-292657-gq3965se 136 24 need need VBP cord-292657-gq3965se 136 25 to to TO cord-292657-gq3965se 136 26 understand understand VB cord-292657-gq3965se 136 27 the the DT cord-292657-gq3965se 136 28 role role NN cord-292657-gq3965se 136 29 of of IN cord-292657-gq3965se 136 30 the the DT cord-292657-gq3965se 136 31 external external JJ cord-292657-gq3965se 136 32 environmental environmental JJ cord-292657-gq3965se 136 33 factors factor NNS cord-292657-gq3965se 136 34 in in IN cord-292657-gq3965se 136 35 the the DT cord-292657-gq3965se 136 36 stability stability NN cord-292657-gq3965se 136 37 and and CC cord-292657-gq3965se 136 38 survival survival NN cord-292657-gq3965se 136 39 of of IN cord-292657-gq3965se 136 40 the the DT cord-292657-gq3965se 136 41 virus virus NN cord-292657-gq3965se 136 42 outside outside IN cord-292657-gq3965se 136 43 the the DT cord-292657-gq3965se 136 44 host host NN cord-292657-gq3965se 136 45 body body NN cord-292657-gq3965se 136 46 conditions condition NNS cord-292657-gq3965se 136 47 . . . cord-292657-gq3965se 137 1 During during IN cord-292657-gq3965se 137 2 the the DT cord-292657-gq3965se 137 3 process process NN cord-292657-gq3965se 137 4 of of IN cord-292657-gq3965se 137 5 evolution evolution NN cord-292657-gq3965se 137 6 , , , cord-292657-gq3965se 137 7 intra intra NNP cord-292657-gq3965se 137 8 or or CC cord-292657-gq3965se 137 9 inter inter JJ cord-292657-gq3965se 137 10 species species NN cord-292657-gq3965se 137 11 transmission transmission NN cord-292657-gq3965se 137 12 among among IN cord-292657-gq3965se 137 13 the the DT cord-292657-gq3965se 137 14 susceptible susceptible JJ cord-292657-gq3965se 137 15 host host NN cord-292657-gq3965se 137 16 community community NN cord-292657-gq3965se 137 17 , , , cord-292657-gq3965se 137 18 external external JJ cord-292657-gq3965se 137 19 environment environment NN cord-292657-gq3965se 137 20 plays play VBZ cord-292657-gq3965se 137 21 a a DT cord-292657-gq3965se 137 22 critical critical JJ cord-292657-gq3965se 137 23 role role NN cord-292657-gq3965se 137 24 . . . cord-292657-gq3965se 138 1 Though though IN cord-292657-gq3965se 138 2 in in IN cord-292657-gq3965se 138 3 the the DT cord-292657-gq3965se 138 4 external external JJ cord-292657-gq3965se 138 5 environment environment NN cord-292657-gq3965se 138 6 , , , cord-292657-gq3965se 138 7 outside outside IN cord-292657-gq3965se 138 8 the the DT cord-292657-gq3965se 138 9 host host NN cord-292657-gq3965se 138 10 body body NN cord-292657-gq3965se 138 11 , , , cord-292657-gq3965se 138 12 the the DT cord-292657-gq3965se 138 13 virus virus NN cord-292657-gq3965se 138 14 can can MD cord-292657-gq3965se 138 15 not not RB cord-292657-gq3965se 138 16 multiply multiply VB cord-292657-gq3965se 138 17 and and CC cord-292657-gq3965se 138 18 cause cause VB cord-292657-gq3965se 138 19 infection infection NN cord-292657-gq3965se 138 20 but but CC cord-292657-gq3965se 138 21 different different JJ cord-292657-gq3965se 138 22 factors factor NNS cord-292657-gq3965se 138 23 are be VBP cord-292657-gq3965se 138 24 crucial crucial JJ cord-292657-gq3965se 138 25 in in IN cord-292657-gq3965se 138 26 the the DT cord-292657-gq3965se 138 27 stability stability NN cord-292657-gq3965se 138 28 of of IN cord-292657-gq3965se 138 29 the the DT cord-292657-gq3965se 138 30 virus virus NN cord-292657-gq3965se 138 31 outside outside IN cord-292657-gq3965se 138 32 its -PRON- PRP$ cord-292657-gq3965se 138 33 host host NN cord-292657-gq3965se 138 34 environment environment NN cord-292657-gq3965se 138 35 for for IN cord-292657-gq3965se 138 36 the the DT cord-292657-gq3965se 138 37 process process NN cord-292657-gq3965se 138 38 of of IN cord-292657-gq3965se 138 39 its -PRON- PRP$ cord-292657-gq3965se 138 40 transmission transmission NN cord-292657-gq3965se 138 41 . . . cord-292657-gq3965se 139 1 Specifically specifically RB cord-292657-gq3965se 139 2 when when WRB cord-292657-gq3965se 139 3 we -PRON- PRP cord-292657-gq3965se 139 4 are be VBP cord-292657-gq3965se 139 5 dealing deal VBG cord-292657-gq3965se 139 6 with with IN cord-292657-gq3965se 139 7 a a DT cord-292657-gq3965se 139 8 respiratory respiratory JJ cord-292657-gq3965se 139 9 tract tract NN cord-292657-gq3965se 139 10 associated associate VBN cord-292657-gq3965se 139 11 virus virus NN cord-292657-gq3965se 139 12 , , , cord-292657-gq3965se 139 13 the the DT cord-292657-gq3965se 139 14 role role NN cord-292657-gq3965se 139 15 of of IN cord-292657-gq3965se 139 16 environmental environmental JJ cord-292657-gq3965se 139 17 factors factor NNS cord-292657-gq3965se 139 18 must must MD cord-292657-gq3965se 139 19 be be VB cord-292657-gq3965se 139 20 emphasized emphasize VBN cord-292657-gq3965se 139 21 because because IN cord-292657-gq3965se 139 22 the the DT cord-292657-gq3965se 139 23 respiratory respiratory JJ cord-292657-gq3965se 139 24 outputs output NNS cord-292657-gq3965se 139 25 are be VBP cord-292657-gq3965se 139 26 directly directly RB cord-292657-gq3965se 139 27 exposed expose VBN cord-292657-gq3965se 139 28 to to IN cord-292657-gq3965se 139 29 the the DT cord-292657-gq3965se 139 30 environment environment NN cord-292657-gq3965se 139 31 through through IN cord-292657-gq3965se 139 32 cough cough NN cord-292657-gq3965se 139 33 , , , cord-292657-gq3965se 139 34 sneeze sneeze VB cord-292657-gq3965se 139 35 , , , cord-292657-gq3965se 139 36 and and CC cord-292657-gq3965se 139 37 sputum sputum NN cord-292657-gq3965se 139 38 . . . cord-292657-gq3965se 140 1 The the DT cord-292657-gq3965se 140 2 role role NN cord-292657-gq3965se 140 3 of of IN cord-292657-gq3965se 140 4 different different JJ cord-292657-gq3965se 140 5 environmental environmental JJ cord-292657-gq3965se 140 6 factors factor NNS cord-292657-gq3965se 140 7 like like IN cord-292657-gq3965se 140 8 temperature temperature NN cord-292657-gq3965se 140 9 , , , cord-292657-gq3965se 140 10 salinity salinity NN cord-292657-gq3965se 140 11 , , , cord-292657-gq3965se 140 12 P p NN cord-292657-gq3965se 140 13 H h NN cord-292657-gq3965se 140 14 etc etc FW cord-292657-gq3965se 140 15 . . . cord-292657-gq3965se 141 1 for for IN cord-292657-gq3965se 141 2 viral viral JJ cord-292657-gq3965se 141 3 stability stability NN cord-292657-gq3965se 141 4 in in IN cord-292657-gq3965se 141 5 aerosol aerosol NN cord-292657-gq3965se 141 6 , , , cord-292657-gq3965se 141 7 inert inert JJ cord-292657-gq3965se 141 8 surface surface NN cord-292657-gq3965se 141 9 , , , cord-292657-gq3965se 141 10 water water NN cord-292657-gq3965se 141 11 etc etc NN cord-292657-gq3965se 141 12 . . . cord-292657-gq3965se 142 1 needs need NNS cord-292657-gq3965se 142 2 to to TO cord-292657-gq3965se 142 3 be be VB cord-292657-gq3965se 142 4 discussed discuss VBN cord-292657-gq3965se 142 5 , , , cord-292657-gq3965se 142 6 because because IN cord-292657-gq3965se 142 7 external external JJ cord-292657-gq3965se 142 8 environment environment NN cord-292657-gq3965se 142 9 is be VBZ cord-292657-gq3965se 142 10 the the DT cord-292657-gq3965se 142 11 connecting connect VBG cord-292657-gq3965se 142 12 media medium NNS cord-292657-gq3965se 142 13 between between IN cord-292657-gq3965se 142 14 various various JJ cord-292657-gq3965se 142 15 host host NN cord-292657-gq3965se 142 16 species specie NNS cord-292657-gq3965se 142 17 during during IN cord-292657-gq3965se 142 18 the the DT cord-292657-gq3965se 142 19 viral viral JJ cord-292657-gq3965se 142 20 transmission transmission NN cord-292657-gq3965se 142 21 . . . cord-292657-gq3965se 143 1 In in IN cord-292657-gq3965se 143 2 case case NN cord-292657-gq3965se 143 3 of of IN cord-292657-gq3965se 143 4 the the DT cord-292657-gq3965se 143 5 other other JJ cord-292657-gq3965se 143 6 two two CD cord-292657-gq3965se 143 7 common common JJ cord-292657-gq3965se 143 8 human human NNP cord-292657-gq3965se 143 9 corona corona NNP cord-292657-gq3965se 143 10 virus virus NN cord-292657-gq3965se 143 11 super super JJ cord-292657-gq3965se 143 12 spread spread NN cord-292657-gq3965se 143 13 , , , cord-292657-gq3965se 143 14 SARS SARS NNP cord-292657-gq3965se 143 15 - - HYPH cord-292657-gq3965se 143 16 CoV-1 CoV-1 NNP cord-292657-gq3965se 143 17 and and CC cord-292657-gq3965se 143 18 MERS MERS NNP cord-292657-gq3965se 143 19 air air NN cord-292657-gq3965se 143 20 transmission transmission NN cord-292657-gq3965se 143 21 is be VBZ cord-292657-gq3965se 143 22 well well RB cord-292657-gq3965se 143 23 reported report VBN cord-292657-gq3965se 143 24 in in IN cord-292657-gq3965se 143 25 form form NN cord-292657-gq3965se 143 26 of of IN cord-292657-gq3965se 143 27 droplet droplet NN cord-292657-gq3965se 143 28 and and CC cord-292657-gq3965se 143 29 aerosol aerosol NN cord-292657-gq3965se 143 30 . . . cord-292657-gq3965se 144 1 The the DT cord-292657-gq3965se 144 2 evolutionary evolutionary JJ cord-292657-gq3965se 144 3 pattern pattern NN cord-292657-gq3965se 144 4 of of IN cord-292657-gq3965se 144 5 SARS SARS NNP cord-292657-gq3965se 144 6 - - HYPH cord-292657-gq3965se 144 7 CoV-2 CoV-2 NNP cord-292657-gq3965se 144 8 is be VBZ cord-292657-gq3965se 144 9 associated associate VBN cord-292657-gq3965se 144 10 with with IN cord-292657-gq3965se 144 11 geographical geographical JJ cord-292657-gq3965se 144 12 continent continent NN cord-292657-gq3965se 144 13 specific specific JJ cord-292657-gq3965se 144 14 subtype subtype NN cord-292657-gq3965se 144 15 diversity diversity NN cord-292657-gq3965se 144 16 with with IN cord-292657-gq3965se 144 17 a a DT cord-292657-gq3965se 144 18 tendency tendency NN cord-292657-gq3965se 144 19 of of IN cord-292657-gq3965se 144 20 rapid rapid JJ cord-292657-gq3965se 144 21 species specie NNS cord-292657-gq3965se 144 22 spill spill NN cord-292657-gq3965se 144 23 over over IN cord-292657-gq3965se 144 24 which which WDT cord-292657-gq3965se 144 25 indicate indicate VBP cord-292657-gq3965se 144 26 towards towards IN cord-292657-gq3965se 144 27 its -PRON- PRP$ cord-292657-gq3965se 144 28 huge huge JJ cord-292657-gq3965se 144 29 external external JJ cord-292657-gq3965se 144 30 environmental environmental JJ cord-292657-gq3965se 144 31 adaptation adaptation NN cord-292657-gq3965se 144 32 . . . cord-292657-gq3965se 145 1 Moreover moreover RB cord-292657-gq3965se 145 2 social social JJ cord-292657-gq3965se 145 3 distancing distancing NN cord-292657-gq3965se 145 4 is be VBZ cord-292657-gq3965se 145 5 emphasized emphasize VBN cord-292657-gq3965se 145 6 for for IN cord-292657-gq3965se 145 7 COVID-19 COVID-19 NNP cord-292657-gq3965se 145 8 spread spread NN cord-292657-gq3965se 145 9 due due IN cord-292657-gq3965se 145 10 to to IN cord-292657-gq3965se 145 11 its -PRON- PRP$ cord-292657-gq3965se 145 12 highly highly RB cord-292657-gq3965se 145 13 contagious contagious JJ cord-292657-gq3965se 145 14 nature nature NN cord-292657-gq3965se 145 15 . . . cord-292657-gq3965se 146 1 Thus thus RB cord-292657-gq3965se 146 2 understanding understand VBG cord-292657-gq3965se 146 3 the the DT cord-292657-gq3965se 146 4 role role NN cord-292657-gq3965se 146 5 of of IN cord-292657-gq3965se 146 6 external external JJ cord-292657-gq3965se 146 7 environmental environmental JJ cord-292657-gq3965se 146 8 factors factor NNS cord-292657-gq3965se 146 9 in in IN cord-292657-gq3965se 146 10 maintaining maintain VBG cord-292657-gq3965se 146 11 viral viral JJ cord-292657-gq3965se 146 12 stability stability NN cord-292657-gq3965se 146 13 and and CC cord-292657-gq3965se 146 14 capability capability NN cord-292657-gq3965se 146 15 to to TO cord-292657-gq3965se 146 16 survive survive VB cord-292657-gq3965se 146 17 in in IN cord-292657-gq3965se 146 18 different different JJ cord-292657-gq3965se 146 19 patient patient NN cord-292657-gq3965se 146 20 samples sample NNS cord-292657-gq3965se 146 21 as as RB cord-292657-gq3965se 146 22 well well RB cord-292657-gq3965se 146 23 as as IN cord-292657-gq3965se 146 24 certain certain JJ cord-292657-gq3965se 146 25 inert inert JJ cord-292657-gq3965se 146 26 or or CC cord-292657-gq3965se 146 27 abiotic abiotic JJ cord-292657-gq3965se 146 28 environmental environmental JJ cord-292657-gq3965se 146 29 substances substance NNS cord-292657-gq3965se 146 30 , , , cord-292657-gq3965se 146 31 the the DT cord-292657-gq3965se 146 32 fomite fomite NN cord-292657-gq3965se 146 33 , , , cord-292657-gq3965se 146 34 by by IN cord-292657-gq3965se 146 35 which which WDT cord-292657-gq3965se 146 36 it -PRON- PRP cord-292657-gq3965se 146 37 can can MD cord-292657-gq3965se 146 38 spread spread VB cord-292657-gq3965se 146 39 needs need NNS cord-292657-gq3965se 146 40 to to TO cord-292657-gq3965se 146 41 be be VB cord-292657-gq3965se 146 42 analyzed analyze VBN cord-292657-gq3965se 146 43 very very RB cord-292657-gq3965se 146 44 well well RB cord-292657-gq3965se 146 45 . . . cord-292657-gq3965se 147 1 If if IN cord-292657-gq3965se 147 2 we -PRON- PRP cord-292657-gq3965se 147 3 consider consider VBP cord-292657-gq3965se 147 4 the the DT cord-292657-gq3965se 147 5 clinical clinical JJ cord-292657-gq3965se 147 6 samples sample NNS cord-292657-gq3965se 147 7 by by IN cord-292657-gq3965se 147 8 which which WDT cord-292657-gq3965se 147 9 the the DT cord-292657-gq3965se 147 10 virus virus NN cord-292657-gq3965se 147 11 is be VBZ cord-292657-gq3965se 147 12 exposed expose VBN cord-292657-gq3965se 147 13 to to IN cord-292657-gq3965se 147 14 the the DT cord-292657-gq3965se 147 15 environment environment NN cord-292657-gq3965se 147 16 , , , cord-292657-gq3965se 147 17 research research NN cord-292657-gq3965se 147 18 shows show VBZ cord-292657-gq3965se 147 19 that that IN cord-292657-gq3965se 147 20 SARS SARS NNP cord-292657-gq3965se 147 21 - - HYPH cord-292657-gq3965se 147 22 CoV-2 CoV-2 NNP cord-292657-gq3965se 147 23 may may MD cord-292657-gq3965se 147 24 present present VB cord-292657-gq3965se 147 25 in in IN cord-292657-gq3965se 147 26 different different JJ cord-292657-gq3965se 147 27 types type NNS cord-292657-gq3965se 147 28 of of IN cord-292657-gq3965se 147 29 patient patient NN cord-292657-gq3965se 147 30 samples sample NNS cord-292657-gq3965se 147 31 . . . cord-292657-gq3965se 148 1 High high JJ cord-292657-gq3965se 148 2 viral viral JJ cord-292657-gq3965se 148 3 load load NN cord-292657-gq3965se 148 4 is be VBZ cord-292657-gq3965se 148 5 found find VBN cord-292657-gq3965se 148 6 mainly mainly RB cord-292657-gq3965se 148 7 in in IN cord-292657-gq3965se 148 8 the the DT cord-292657-gq3965se 148 9 respiratory respiratory JJ cord-292657-gq3965se 148 10 samples sample NNS cord-292657-gq3965se 148 11 . . . cord-292657-gq3965se 149 1 Presence presence NN cord-292657-gq3965se 149 2 of of IN cord-292657-gq3965se 149 3 virus virus NN cord-292657-gq3965se 149 4 in in IN cord-292657-gq3965se 149 5 blood blood NN cord-292657-gq3965se 149 6 samples sample NNS cord-292657-gq3965se 149 7 proves prove VBZ cord-292657-gq3965se 149 8 its -PRON- PRP$ cord-292657-gq3965se 149 9 systemic systemic JJ cord-292657-gq3965se 149 10 spread spread NN cord-292657-gq3965se 149 11 . . . cord-292657-gq3965se 150 1 Detection detection NN cord-292657-gq3965se 150 2 of of IN cord-292657-gq3965se 150 3 live live JJ cord-292657-gq3965se 150 4 viral viral JJ cord-292657-gq3965se 150 5 particle particle NN cord-292657-gq3965se 150 6 in in IN cord-292657-gq3965se 150 7 feces fece NNS cord-292657-gq3965se 150 8 indicates indicate VBZ cord-292657-gq3965se 150 9 its -PRON- PRP$ cord-292657-gq3965se 150 10 fecal fecal JJ cord-292657-gq3965se 150 11 - - HYPH cord-292657-gq3965se 150 12 oral oral JJ cord-292657-gq3965se 150 13 route route NN cord-292657-gq3965se 150 14 of of IN cord-292657-gq3965se 150 15 environmental environmental JJ cord-292657-gq3965se 150 16 exposure exposure NN cord-292657-gq3965se 150 17 [ [ -LRB- cord-292657-gq3965se 150 18 6 6 CD cord-292657-gq3965se 150 19 , , , cord-292657-gq3965se 150 20 30 30 CD cord-292657-gq3965se 150 21 ] ] -RRB- cord-292657-gq3965se 150 22 . . . cord-292657-gq3965se 151 1 After after IN cord-292657-gq3965se 151 2 the the DT cord-292657-gq3965se 151 3 virus virus NN cord-292657-gq3965se 151 4 is be VBZ cord-292657-gq3965se 151 5 exposed expose VBN cord-292657-gq3965se 151 6 to to IN cord-292657-gq3965se 151 7 environment environment NN cord-292657-gq3965se 151 8 by by IN cord-292657-gq3965se 151 9 these these DT cord-292657-gq3965se 151 10 clinical clinical JJ cord-292657-gq3965se 151 11 samples sample NNS cord-292657-gq3965se 151 12 , , , cord-292657-gq3965se 151 13 SARS SARS NNP cord-292657-gq3965se 151 14 - - HYPH cord-292657-gq3965se 151 15 CoV-2 CoV-2 NNP cord-292657-gq3965se 151 16 shows show VBZ cord-292657-gq3965se 151 17 various various JJ cord-292657-gq3965se 151 18 degree degree NN cord-292657-gq3965se 151 19 of of IN cord-292657-gq3965se 151 20 fomite fomite NN cord-292657-gq3965se 151 21 stability stability NN cord-292657-gq3965se 151 22 for for IN cord-292657-gq3965se 151 23 different different JJ cord-292657-gq3965se 151 24 surfaces surface NNS cord-292657-gq3965se 151 25 associated associate VBN cord-292657-gq3965se 151 26 to to IN cord-292657-gq3965se 151 27 those those DT cord-292657-gq3965se 151 28 patient patient JJ cord-292657-gq3965se 151 29 samples sample NNS cord-292657-gq3965se 151 30 . . . cord-292657-gq3965se 152 1 In in IN cord-292657-gq3965se 152 2 case case NN cord-292657-gq3965se 152 3 of of IN cord-292657-gq3965se 152 4 steel steel NN cord-292657-gq3965se 152 5 surface surface NN cord-292657-gq3965se 152 6 , , , cord-292657-gq3965se 152 7 the the DT cord-292657-gq3965se 152 8 stability stability NN cord-292657-gq3965se 152 9 is be VBZ cord-292657-gq3965se 152 10 maximum maximum JJ cord-292657-gq3965se 152 11 ( ( -LRB- cord-292657-gq3965se 152 12 approximately approximately RB cord-292657-gq3965se 152 13 2 2 CD cord-292657-gq3965se 152 14 - - SYM cord-292657-gq3965se 152 15 3 3 CD cord-292657-gq3965se 152 16 days day NNS cord-292657-gq3965se 152 17 ) ) -RRB- cord-292657-gq3965se 152 18 . . . cord-292657-gq3965se 153 1 It -PRON- PRP cord-292657-gq3965se 153 2 is be VBZ cord-292657-gq3965se 153 3 also also RB cord-292657-gq3965se 153 4 stable stable JJ cord-292657-gq3965se 153 5 in in IN cord-292657-gq3965se 153 6 polypropylene polypropylene NN cord-292657-gq3965se 153 7 , , , cord-292657-gq3965se 153 8 card card NN cord-292657-gq3965se 153 9 board board NN cord-292657-gq3965se 153 10 and and CC cord-292657-gq3965se 153 11 copper copper NN cord-292657-gq3965se 153 12 ( ( -LRB- cord-292657-gq3965se 153 13 show show VB cord-292657-gq3965se 153 14 less less JJR cord-292657-gq3965se 153 15 degree degree NN cord-292657-gq3965se 153 16 of of IN cord-292657-gq3965se 153 17 stability stability NN cord-292657-gq3965se 153 18 ) ) -RRB- cord-292657-gq3965se 153 19 . . . cord-292657-gq3965se 154 1 In in IN cord-292657-gq3965se 154 2 aerosol aerosol NN cord-292657-gq3965se 154 3 the the DT cord-292657-gq3965se 154 4 virus virus NN cord-292657-gq3965se 154 5 shows show VBZ cord-292657-gq3965se 154 6 three three CD cord-292657-gq3965se 154 7 hours hour NNS cord-292657-gq3965se 154 8 of of IN cord-292657-gq3965se 154 9 stability stability NN cord-292657-gq3965se 154 10 [ [ -LRB- cord-292657-gq3965se 154 11 27 27 CD cord-292657-gq3965se 154 12 ] ] -RRB- cord-292657-gq3965se 154 13 . . . cord-292657-gq3965se 155 1 In in IN cord-292657-gq3965se 155 2 connection connection NN cord-292657-gq3965se 155 3 with with IN cord-292657-gq3965se 155 4 the the DT cord-292657-gq3965se 155 5 fecal fecal JJ cord-292657-gq3965se 155 6 - - HYPH cord-292657-gq3965se 155 7 oral oral JJ cord-292657-gq3965se 155 8 route route NN cord-292657-gq3965se 155 9 the the DT cord-292657-gq3965se 155 10 stability stability NN cord-292657-gq3965se 155 11 and and CC cord-292657-gq3965se 155 12 sustainability sustainability NN cord-292657-gq3965se 155 13 of of IN cord-292657-gq3965se 155 14 SARS SARS NNP cord-292657-gq3965se 155 15 - - HYPH cord-292657-gq3965se 155 16 CoV-2 CoV-2 NNP cord-292657-gq3965se 155 17 has have VBZ cord-292657-gq3965se 155 18 been be VBN cord-292657-gq3965se 155 19 found find VBN cord-292657-gq3965se 155 20 in in IN cord-292657-gq3965se 155 21 waste waste NN cord-292657-gq3965se 155 22 and and CC cord-292657-gq3965se 155 23 sanitary sanitary JJ cord-292657-gq3965se 155 24 water water NN cord-292657-gq3965se 155 25 in in IN cord-292657-gq3965se 155 26 infected infected JJ cord-292657-gq3965se 155 27 area area NN cord-292657-gq3965se 155 28 , , , cord-292657-gq3965se 155 29 is be VBZ cord-292657-gq3965se 155 30 recently recently RB cord-292657-gq3965se 155 31 reported report VBN cord-292657-gq3965se 155 32 [ [ -LRB- cord-292657-gq3965se 155 33 18 18 CD cord-292657-gq3965se 155 34 ] ] -RRB- cord-292657-gq3965se 155 35 . . . cord-292657-gq3965se 156 1 The the DT cord-292657-gq3965se 156 2 stability stability NN cord-292657-gq3965se 156 3 of of IN cord-292657-gq3965se 156 4 virus virus NN cord-292657-gq3965se 156 5 in in IN cord-292657-gq3965se 156 6 different different JJ cord-292657-gq3965se 156 7 contaminated contaminated JJ cord-292657-gq3965se 156 8 surfaces surface NNS cord-292657-gq3965se 156 9 and and CC cord-292657-gq3965se 156 10 in in IN cord-292657-gq3965se 156 11 different different JJ cord-292657-gq3965se 156 12 patient patient NN cord-292657-gq3965se 156 13 sample sample NN cord-292657-gq3965se 156 14 outputs output NNS cord-292657-gq3965se 156 15 depends depend VBZ cord-292657-gq3965se 156 16 on on IN cord-292657-gq3965se 156 17 the the DT cord-292657-gq3965se 156 18 action action NN cord-292657-gq3965se 156 19 of of IN cord-292657-gq3965se 156 20 temperature temperature NN cord-292657-gq3965se 156 21 and and CC cord-292657-gq3965se 156 22 relative relative JJ cord-292657-gq3965se 156 23 humidity humidity NN cord-292657-gq3965se 156 24 percentage percentage NN cord-292657-gq3965se 156 25 . . . cord-292657-gq3965se 157 1 It -PRON- PRP cord-292657-gq3965se 157 2 has have VBZ cord-292657-gq3965se 157 3 been be VBN cord-292657-gq3965se 157 4 observed observe VBN cord-292657-gq3965se 157 5 for for IN cord-292657-gq3965se 157 6 corona corona NN cord-292657-gq3965se 157 7 virus virus NN cord-292657-gq3965se 157 8 that that WDT cord-292657-gq3965se 157 9 low low JJ cord-292657-gq3965se 157 10 temperature temperature NN cord-292657-gq3965se 157 11 ( ( -LRB- cord-292657-gq3965se 157 12 4 4 CD cord-292657-gq3965se 157 13 degree degree NN cord-292657-gq3965se 157 14 ) ) -RRB- cord-292657-gq3965se 157 15 and and CC cord-292657-gq3965se 157 16 low low JJ cord-292657-gq3965se 157 17 humidity humidity NN cord-292657-gq3965se 157 18 ( ( -LRB- cord-292657-gq3965se 157 19 20 20 CD cord-292657-gq3965se 157 20 % % NN cord-292657-gq3965se 157 21 ) ) -RRB- cord-292657-gq3965se 157 22 is be VBZ cord-292657-gq3965se 157 23 supportive supportive JJ cord-292657-gq3965se 157 24 for for IN cord-292657-gq3965se 157 25 the the DT cord-292657-gq3965se 157 26 viral viral JJ cord-292657-gq3965se 157 27 stability stability NN cord-292657-gq3965se 157 28 , , , cord-292657-gq3965se 157 29 where where WRB cord-292657-gq3965se 157 30 gradual gradual JJ cord-292657-gq3965se 157 31 increase increase NN cord-292657-gq3965se 157 32 of of IN cord-292657-gq3965se 157 33 both both CC cord-292657-gq3965se 157 34 the the DT cord-292657-gq3965se 157 35 parameters parameter NNS cord-292657-gq3965se 157 36 inactivates inactivate VBZ cord-292657-gq3965se 157 37 the the DT cord-292657-gq3965se 157 38 virus virus NN cord-292657-gq3965se 157 39 more more RBR cord-292657-gq3965se 157 40 rapidly rapidly RB cord-292657-gq3965se 157 41 . . . cord-292657-gq3965se 158 1 It -PRON- PRP cord-292657-gq3965se 158 2 has have VBZ cord-292657-gq3965se 158 3 been be VBN cord-292657-gq3965se 158 4 observed observe VBN cord-292657-gq3965se 158 5 that that IN cord-292657-gq3965se 158 6 lipid lipid NN cord-292657-gq3965se 158 7 virus virus NN cord-292657-gq3965se 158 8 like like IN cord-292657-gq3965se 158 9 COVID COVID NNP cord-292657-gq3965se 158 10 can can MD cord-292657-gq3965se 158 11 be be VB cord-292657-gq3965se 158 12 inactivated inactivate VBN cord-292657-gq3965se 158 13 by by IN cord-292657-gq3965se 158 14 the the DT cord-292657-gq3965se 158 15 interference interference NN cord-292657-gq3965se 158 16 of of IN cord-292657-gq3965se 158 17 two two CD cord-292657-gq3965se 158 18 mechanisms mechanism NNS cord-292657-gq3965se 158 19 , , , cord-292657-gq3965se 158 20 the the DT cord-292657-gq3965se 158 21 air air NN cord-292657-gq3965se 158 22 water water NN cord-292657-gq3965se 158 23 interphase interphase NN cord-292657-gq3965se 158 24 and and CC cord-292657-gq3965se 158 25 desiccation desiccation NN cord-292657-gq3965se 158 26 process process NN cord-292657-gq3965se 158 27 . . . cord-292657-gq3965se 159 1 When when WRB cord-292657-gq3965se 159 2 the the DT cord-292657-gq3965se 159 3 relative relative JJ cord-292657-gq3965se 159 4 humidity humidity NN cord-292657-gq3965se 159 5 is be VBZ cord-292657-gq3965se 159 6 nearly nearly RB cord-292657-gq3965se 159 7 50 50 CD cord-292657-gq3965se 159 8 % % NN cord-292657-gq3965se 159 9 , , , cord-292657-gq3965se 159 10 the the DT cord-292657-gq3965se 159 11 virus virus NN cord-292657-gq3965se 159 12 is be VBZ cord-292657-gq3965se 159 13 accumulated accumulate VBN cord-292657-gq3965se 159 14 by by IN cord-292657-gq3965se 159 15 the the DT cord-292657-gq3965se 159 16 air air NN cord-292657-gq3965se 159 17 water water NN cord-292657-gq3965se 159 18 interphase interphase NN cord-292657-gq3965se 159 19 . . . cord-292657-gq3965se 160 1 Then then RB cord-292657-gq3965se 160 2 the the DT cord-292657-gq3965se 160 3 desiccation desiccation NN cord-292657-gq3965se 160 4 process process NN cord-292657-gq3965se 160 5 excretes excrete VBZ cord-292657-gq3965se 160 6 water water NN cord-292657-gq3965se 160 7 from from IN cord-292657-gq3965se 160 8 the the DT cord-292657-gq3965se 160 9 lipid lipid NN cord-292657-gq3965se 160 10 layer layer NN cord-292657-gq3965se 160 11 by by IN cord-292657-gq3965se 160 12 oxidation oxidation NN cord-292657-gq3965se 160 13 and and CC cord-292657-gq3965se 160 14 simultaneously simultaneously RB cord-292657-gq3965se 160 15 breaks break VBZ cord-292657-gq3965se 160 16 the the DT cord-292657-gq3965se 160 17 cross cross NN cord-292657-gq3965se 160 18 linking linking NN cord-292657-gq3965se 160 19 thus thus RB cord-292657-gq3965se 160 20 which which WDT cord-292657-gq3965se 160 21 effectively effectively RB cord-292657-gq3965se 160 22 damage damage VBP cord-292657-gq3965se 160 23 the the DT cord-292657-gq3965se 160 24 lipid lipid NN cord-292657-gq3965se 160 25 layer layer NN cord-292657-gq3965se 160 26 of of IN cord-292657-gq3965se 160 27 the the DT cord-292657-gq3965se 160 28 pathogen pathogen NN cord-292657-gq3965se 160 29 much much RB cord-292657-gq3965se 160 30 rapidly rapidly RB cord-292657-gq3965se 160 31 [ [ -LRB- cord-292657-gq3965se 160 32 4 4 CD cord-292657-gq3965se 160 33 ] ] -RRB- cord-292657-gq3965se 160 34 . . . cord-292657-gq3965se 161 1 On on IN cord-292657-gq3965se 161 2 this this DT cord-292657-gq3965se 161 3 note note NN cord-292657-gq3965se 161 4 it -PRON- PRP cord-292657-gq3965se 161 5 must must MD cord-292657-gq3965se 161 6 be be VB cord-292657-gq3965se 161 7 pointed point VBN cord-292657-gq3965se 161 8 that that IN cord-292657-gq3965se 161 9 mucus mucus NN cord-292657-gq3965se 161 10 acts act VBZ cord-292657-gq3965se 161 11 as as IN cord-292657-gq3965se 161 12 the the DT cord-292657-gq3965se 161 13 first first JJ cord-292657-gq3965se 161 14 protective protective JJ cord-292657-gq3965se 161 15 barrier barrier NN cord-292657-gq3965se 161 16 for for IN cord-292657-gq3965se 161 17 invading invade VBG cord-292657-gq3965se 161 18 respiratory respiratory JJ cord-292657-gq3965se 161 19 virus virus NN cord-292657-gq3965se 161 20 . . . cord-292657-gq3965se 162 1 Interaction interaction NN cord-292657-gq3965se 162 2 of of IN cord-292657-gq3965se 162 3 mucus mucus NN cord-292657-gq3965se 162 4 layer layer NN cord-292657-gq3965se 162 5 glycoprotein glycoprotein NN cord-292657-gq3965se 162 6 with with IN cord-292657-gq3965se 162 7 viral viral JJ cord-292657-gq3965se 162 8 surface surface NN cord-292657-gq3965se 162 9 proteins protein NNS cord-292657-gq3965se 162 10 have have VBP cord-292657-gq3965se 162 11 been be VBN cord-292657-gq3965se 162 12 well well RB cord-292657-gq3965se 162 13 reported report VBN cord-292657-gq3965se 162 14 in in IN cord-292657-gq3965se 162 15 influenza influenza NN cord-292657-gq3965se 162 16 virus virus NN cord-292657-gq3965se 162 17 . . . cord-292657-gq3965se 163 1 Recent recent JJ cord-292657-gq3965se 163 2 research research NN cord-292657-gq3965se 163 3 shows show VBZ cord-292657-gq3965se 163 4 that that IN cord-292657-gq3965se 163 5 the the DT cord-292657-gq3965se 163 6 saliva saliva NN cord-292657-gq3965se 163 7 or or CC cord-292657-gq3965se 163 8 mucus mucus NN cord-292657-gq3965se 163 9 substance substance NN cord-292657-gq3965se 163 10 may may MD cord-292657-gq3965se 163 11 act act VB cord-292657-gq3965se 163 12 as as IN cord-292657-gq3965se 163 13 a a DT cord-292657-gq3965se 163 14 protective protective JJ cord-292657-gq3965se 163 15 barrier barrier NN cord-292657-gq3965se 163 16 for for IN cord-292657-gq3965se 163 17 the the DT cord-292657-gq3965se 163 18 virus virus NN cord-292657-gq3965se 163 19 when when WRB cord-292657-gq3965se 163 20 it -PRON- PRP cord-292657-gq3965se 163 21 is be VBZ cord-292657-gq3965se 163 22 exposed expose VBN cord-292657-gq3965se 163 23 to to IN cord-292657-gq3965se 163 24 the the DT cord-292657-gq3965se 163 25 external external JJ cord-292657-gq3965se 163 26 environment environment NN cord-292657-gq3965se 163 27 . . . cord-292657-gq3965se 164 1 The the DT cord-292657-gq3965se 164 2 aerosol aerosol NN cord-292657-gq3965se 164 3 also also RB cord-292657-gq3965se 164 4 goes go VBZ cord-292657-gq3965se 164 5 with with IN cord-292657-gq3965se 164 6 the the DT cord-292657-gq3965se 164 7 same same JJ cord-292657-gq3965se 164 8 flow flow NN cord-292657-gq3965se 164 9 , , , cord-292657-gq3965se 164 10 where where WRB cord-292657-gq3965se 164 11 it -PRON- PRP cord-292657-gq3965se 164 12 helps help VBZ cord-292657-gq3965se 164 13 the the DT cord-292657-gq3965se 164 14 virus virus NN cord-292657-gq3965se 164 15 from from IN cord-292657-gq3965se 164 16 the the DT cord-292657-gq3965se 164 17 hazardous hazardous JJ cord-292657-gq3965se 164 18 effect effect NN cord-292657-gq3965se 164 19 of of IN cord-292657-gq3965se 164 20 varying vary VBG cord-292657-gq3965se 164 21 external external JJ cord-292657-gq3965se 164 22 environment environment NN cord-292657-gq3965se 164 23 by by IN cord-292657-gq3965se 164 24 retaining retain VBG cord-292657-gq3965se 164 25 its -PRON- PRP$ cord-292657-gq3965se 164 26 infectivity infectivity NN cord-292657-gq3965se 164 27 [ [ -LRB- cord-292657-gq3965se 164 28 11 11 CD cord-292657-gq3965se 164 29 , , , cord-292657-gq3965se 164 30 33 33 CD cord-292657-gq3965se 164 31 ] ] -RRB- cord-292657-gq3965se 164 32 . . . cord-292657-gq3965se 165 1 So so RB cord-292657-gq3965se 165 2 temperature temperature NN cord-292657-gq3965se 165 3 inactivation inactivation NN cord-292657-gq3965se 165 4 or or CC cord-292657-gq3965se 165 5 the the DT cord-292657-gq3965se 165 6 air air NN cord-292657-gq3965se 165 7 water water NN cord-292657-gq3965se 165 8 desiccation desiccation NN cord-292657-gq3965se 165 9 mechanism mechanism NN cord-292657-gq3965se 165 10 , , , cord-292657-gq3965se 165 11 are be VBP cord-292657-gq3965se 165 12 not not RB cord-292657-gq3965se 165 13 effective effective JJ cord-292657-gq3965se 165 14 on on IN cord-292657-gq3965se 165 15 the the DT cord-292657-gq3965se 165 16 virus virus NN cord-292657-gq3965se 165 17 when when WRB cord-292657-gq3965se 165 18 the the DT cord-292657-gq3965se 165 19 organic organic JJ cord-292657-gq3965se 165 20 barriers barrier NNS cord-292657-gq3965se 165 21 acts act VBZ cord-292657-gq3965se 165 22 as as IN cord-292657-gq3965se 165 23 insulator insulator NN cord-292657-gq3965se 165 24 . . . cord-292657-gq3965se 166 1 Thus thus RB cord-292657-gq3965se 166 2 in in IN cord-292657-gq3965se 166 3 case case NN cord-292657-gq3965se 166 4 of of IN cord-292657-gq3965se 166 5 SARS SARS NNP cord-292657-gq3965se 166 6 - - HYPH cord-292657-gq3965se 166 7 C0V-2 C0V-2 NNP cord-292657-gq3965se 166 8 , , , cord-292657-gq3965se 166 9 it -PRON- PRP cord-292657-gq3965se 166 10 is be VBZ cord-292657-gq3965se 166 11 received receive VBN cord-292657-gq3965se 166 12 by by IN cord-292657-gq3965se 166 13 the the DT cord-292657-gq3965se 166 14 environment environment NN cord-292657-gq3965se 166 15 through through IN cord-292657-gq3965se 166 16 different different JJ cord-292657-gq3965se 166 17 clinical clinical JJ cord-292657-gq3965se 166 18 sample sample NN cord-292657-gq3965se 166 19 outputs output NNS cord-292657-gq3965se 166 20 mainly mainly RB cord-292657-gq3965se 166 21 the the DT cord-292657-gq3965se 166 22 respiratory respiratory JJ cord-292657-gq3965se 166 23 secretions secretion NNS cord-292657-gq3965se 166 24 from from IN cord-292657-gq3965se 166 25 an an DT cord-292657-gq3965se 166 26 infected infected JJ cord-292657-gq3965se 166 27 person person NN cord-292657-gq3965se 166 28 whether whether IN cord-292657-gq3965se 166 29 it -PRON- PRP cord-292657-gq3965se 166 30 is be VBZ cord-292657-gq3965se 166 31 a a DT cord-292657-gq3965se 166 32 susceptible susceptible JJ cord-292657-gq3965se 166 33 host host NN cord-292657-gq3965se 166 34 or or CC cord-292657-gq3965se 166 35 carrier carrier NN cord-292657-gq3965se 166 36 , , , cord-292657-gq3965se 166 37 in in IN cord-292657-gq3965se 166 38 form form NN cord-292657-gq3965se 166 39 of of IN cord-292657-gq3965se 166 40 droplets droplet NNS cord-292657-gq3965se 166 41 or or CC cord-292657-gq3965se 166 42 aerosol aerosol NN cord-292657-gq3965se 166 43 and and CC cord-292657-gq3965se 166 44 can can MD cord-292657-gq3965se 166 45 survive survive VB cord-292657-gq3965se 166 46 in in IN cord-292657-gq3965se 166 47 this this DT cord-292657-gq3965se 166 48 form form NN cord-292657-gq3965se 166 49 in in IN cord-292657-gq3965se 166 50 various various JJ cord-292657-gq3965se 166 51 fomites fomite NNS cord-292657-gq3965se 166 52 . . . cord-292657-gq3965se 167 1 After after IN cord-292657-gq3965se 167 2 the the DT cord-292657-gq3965se 167 3 virus virus NN cord-292657-gq3965se 167 4 is be VBZ cord-292657-gq3965se 167 5 received receive VBN cord-292657-gq3965se 167 6 in in IN cord-292657-gq3965se 167 7 the the DT cord-292657-gq3965se 167 8 external external JJ cord-292657-gq3965se 167 9 environment environment NN cord-292657-gq3965se 167 10 , , , cord-292657-gq3965se 167 11 the the DT cord-292657-gq3965se 167 12 patient patient NN cord-292657-gq3965se 167 13 sample sample NN cord-292657-gq3965se 167 14 itself -PRON- PRP cord-292657-gq3965se 167 15 protects protect VBZ cord-292657-gq3965se 167 16 it -PRON- PRP cord-292657-gq3965se 167 17 from from IN cord-292657-gq3965se 167 18 adverse adverse JJ cord-292657-gq3965se 167 19 environmental environmental JJ cord-292657-gq3965se 167 20 conditions condition NNS cord-292657-gq3965se 167 21 and and CC cord-292657-gq3965se 167 22 helps help VBZ cord-292657-gq3965se 167 23 it -PRON- PRP cord-292657-gq3965se 167 24 to to TO cord-292657-gq3965se 167 25 survive survive VB cord-292657-gq3965se 167 26 or or CC cord-292657-gq3965se 167 27 sustain sustain VB cord-292657-gq3965se 167 28 for for IN cord-292657-gq3965se 167 29 long long JJ cord-292657-gq3965se 167 30 time time NN cord-292657-gq3965se 167 31 acting act VBG cord-292657-gq3965se 167 32 as as IN cord-292657-gq3965se 167 33 maintaining maintain VBG cord-292657-gq3965se 167 34 media medium NNS cord-292657-gq3965se 167 35 for for IN cord-292657-gq3965se 167 36 the the DT cord-292657-gq3965se 167 37 virus virus NN cord-292657-gq3965se 167 38 outside outside IN cord-292657-gq3965se 167 39 the the DT cord-292657-gq3965se 167 40 host host NN cord-292657-gq3965se 167 41 body body NN cord-292657-gq3965se 167 42 . . . cord-292657-gq3965se 168 1 This this DT cord-292657-gq3965se 168 2 is be VBZ cord-292657-gq3965se 168 3 the the DT cord-292657-gq3965se 168 4 probable probable JJ cord-292657-gq3965se 168 5 reason reason NN cord-292657-gq3965se 168 6 why why WRB cord-292657-gq3965se 168 7 SARS SARS NNP cord-292657-gq3965se 168 8 - - HYPH cord-292657-gq3965se 168 9 CoV-2 CoV-2 NNP cord-292657-gq3965se 168 10 shows show VBZ cord-292657-gq3965se 168 11 high high JJ cord-292657-gq3965se 168 12 degree degree NN cord-292657-gq3965se 168 13 of of IN cord-292657-gq3965se 168 14 external external JJ cord-292657-gq3965se 168 15 environment environment NN cord-292657-gq3965se 168 16 stability stability NN cord-292657-gq3965se 168 17 . . . cord-292657-gq3965se 169 1 From from IN cord-292657-gq3965se 169 2 the the DT cord-292657-gq3965se 169 3 above above JJ cord-292657-gq3965se 169 4 analysis analysis NN cord-292657-gq3965se 169 5 it -PRON- PRP cord-292657-gq3965se 169 6 is be VBZ cord-292657-gq3965se 169 7 clear clear JJ cord-292657-gq3965se 169 8 that that IN cord-292657-gq3965se 169 9 the the DT cord-292657-gq3965se 169 10 outside outside JJ cord-292657-gq3965se 169 11 host host NN cord-292657-gq3965se 169 12 environment environment NN cord-292657-gq3965se 169 13 acts act VBZ cord-292657-gq3965se 169 14 as as IN cord-292657-gq3965se 169 15 the the DT cord-292657-gq3965se 169 16 intermediate intermediate JJ cord-292657-gq3965se 169 17 player player NN cord-292657-gq3965se 169 18 which which WDT cord-292657-gq3965se 169 19 receives receive VBZ cord-292657-gq3965se 169 20 , , , cord-292657-gq3965se 169 21 maintains maintain VBZ cord-292657-gq3965se 169 22 , , , cord-292657-gq3965se 169 23 protects protect VBZ cord-292657-gq3965se 169 24 and and CC cord-292657-gq3965se 169 25 transfers transfer VBZ cord-292657-gq3965se 169 26 the the DT cord-292657-gq3965se 169 27 pathogen pathogen NN cord-292657-gq3965se 169 28 using use VBG cord-292657-gq3965se 169 29 its -PRON- PRP$ cord-292657-gq3965se 169 30 various various JJ cord-292657-gq3965se 169 31 factors factor NNS cord-292657-gq3965se 169 32 as as IN cord-292657-gq3965se 169 33 weapon weapon NN cord-292657-gq3965se 169 34 for for IN cord-292657-gq3965se 169 35 COVID-19 covid-19 JJ cord-292657-gq3965se 169 36 pandemic pandemic NN cord-292657-gq3965se 169 37 . . . cord-292657-gq3965se 170 1 Decoding decode VBG cord-292657-gq3965se 170 2 the the DT cord-292657-gq3965se 170 3 global global JJ cord-292657-gq3965se 170 4 outbreak outbreak NN cord-292657-gq3965se 170 5 of of IN cord-292657-gq3965se 170 6 COVID-19 COVID-19 NNP cord-292657-gq3965se 170 7 : : : cord-292657-gq3965se 170 8 the the DT cord-292657-gq3965se 170 9 nature nature NN cord-292657-gq3965se 170 10 is be VBZ cord-292657-gq3965se 170 11 behind behind IN cord-292657-gq3965se 170 12 the the DT cord-292657-gq3965se 170 13 scene scene NN cord-292657-gq3965se 170 14 From from IN cord-292657-gq3965se 170 15 the the DT cord-292657-gq3965se 170 16 above above JJ cord-292657-gq3965se 170 17 study study NN cord-292657-gq3965se 171 1 it -PRON- PRP cord-292657-gq3965se 171 2 is be VBZ cord-292657-gq3965se 171 3 clear clear JJ cord-292657-gq3965se 171 4 that that IN cord-292657-gq3965se 171 5 rapid rapid JJ cord-292657-gq3965se 171 6 evolving evolve VBG cord-292657-gq3965se 171 7 nature nature NN cord-292657-gq3965se 171 8 and and CC cord-292657-gq3965se 171 9 high high JJ cord-292657-gq3965se 171 10 environmental environmental JJ cord-292657-gq3965se 171 11 stability stability NN cord-292657-gq3965se 171 12 of of IN cord-292657-gq3965se 171 13 SARS SARS NNP cord-292657-gq3965se 171 14 - - HYPH cord-292657-gq3965se 171 15 CoV-2 CoV-2 NNP cord-292657-gq3965se 171 16 is be VBZ cord-292657-gq3965se 171 17 responsible responsible JJ cord-292657-gq3965se 171 18 for for IN cord-292657-gq3965se 171 19 the the DT cord-292657-gq3965se 171 20 current current JJ cord-292657-gq3965se 171 21 outbreak outbreak NN cord-292657-gq3965se 171 22 of of IN cord-292657-gq3965se 171 23 COVID-19 COVID-19 NNP cord-292657-gq3965se 171 24 . . . cord-292657-gq3965se 172 1 The the DT cord-292657-gq3965se 172 2 evolutionary evolutionary JJ cord-292657-gq3965se 172 3 process process NN cord-292657-gq3965se 172 4 of of IN cord-292657-gq3965se 172 5 this this DT cord-292657-gq3965se 172 6 new new JJ cord-292657-gq3965se 172 7 version version NN cord-292657-gq3965se 172 8 of of IN cord-292657-gq3965se 172 9 the the DT cord-292657-gq3965se 172 10 virus virus NN cord-292657-gq3965se 172 11 indicates indicate VBZ cord-292657-gq3965se 172 12 the the DT cord-292657-gq3965se 172 13 ' ' `` cord-292657-gq3965se 172 14 synthetic synthetic JJ cord-292657-gq3965se 172 15 theory theory NN cord-292657-gq3965se 172 16 of of IN cord-292657-gq3965se 172 17 evolution evolution NN cord-292657-gq3965se 172 18 ' ' '' cord-292657-gq3965se 172 19 or or CC cord-292657-gq3965se 172 20 the the DT cord-292657-gq3965se 172 21 ' ' `` cord-292657-gq3965se 172 22 Neo Neo NNP cord-292657-gq3965se 172 23 - - HYPH cord-292657-gq3965se 172 24 Darwinism Darwinism NNP cord-292657-gq3965se 172 25 theory theory NN cord-292657-gq3965se 172 26 ' ' '' cord-292657-gq3965se 172 27 where where WRB cord-292657-gq3965se 172 28 , , , cord-292657-gq3965se 172 29 the the DT cord-292657-gq3965se 172 30 virus virus NN cord-292657-gq3965se 172 31 has have VBZ cord-292657-gq3965se 172 32 gone go VBN cord-292657-gq3965se 172 33 through through IN cord-292657-gq3965se 172 34 sequential sequential JJ cord-292657-gq3965se 172 35 multistep multistep JJ cord-292657-gq3965se 172 36 thorough thorough JJ cord-292657-gq3965se 172 37 process process NN cord-292657-gq3965se 172 38 of of IN cord-292657-gq3965se 172 39 molecular molecular JJ cord-292657-gq3965se 172 40 genetic genetic JJ cord-292657-gq3965se 172 41 variation variation NN cord-292657-gq3965se 172 42 which which WDT cord-292657-gq3965se 172 43 is be VBZ cord-292657-gq3965se 172 44 shaped shape VBN cord-292657-gq3965se 172 45 and and CC cord-292657-gq3965se 172 46 established establish VBN cord-292657-gq3965se 172 47 by by IN cord-292657-gq3965se 172 48 the the DT cord-292657-gq3965se 172 49 natural natural JJ cord-292657-gq3965se 172 50 selection selection NN cord-292657-gq3965se 172 51 process process NN cord-292657-gq3965se 172 52 . . . cord-292657-gq3965se 173 1 In in IN cord-292657-gq3965se 173 2 this this DT cord-292657-gq3965se 173 3 review review NN cord-292657-gq3965se 173 4 the the DT cord-292657-gq3965se 173 5 role role NN cord-292657-gq3965se 173 6 of of IN cord-292657-gq3965se 173 7 both both CC cord-292657-gq3965se 173 8 the the DT cord-292657-gq3965se 173 9 host host NN cord-292657-gq3965se 173 10 body body NN cord-292657-gq3965se 173 11 environment environment NN cord-292657-gq3965se 173 12 and and CC cord-292657-gq3965se 173 13 the the DT cord-292657-gq3965se 173 14 external external JJ cord-292657-gq3965se 173 15 environment environment NN cord-292657-gq3965se 173 16 in in IN cord-292657-gq3965se 173 17 disease disease NN cord-292657-gq3965se 173 18 establishment establishment NN cord-292657-gq3965se 173 19 is be VBZ cord-292657-gq3965se 173 20 discussed discuss VBN cord-292657-gq3965se 173 21 from from IN cord-292657-gq3965se 173 22 different different JJ cord-292657-gq3965se 173 23 angle angle NN cord-292657-gq3965se 173 24 ( ( -LRB- cord-292657-gq3965se 173 25 Fig fig NN cord-292657-gq3965se 173 26 . . . cord-292657-gq3965se 173 27 1 1 CD cord-292657-gq3965se 173 28 ) ) -RRB- cord-292657-gq3965se 173 29 . . . cord-292657-gq3965se 174 1 The the DT cord-292657-gq3965se 174 2 host host NN cord-292657-gq3965se 174 3 body body NN cord-292657-gq3965se 174 4 is be VBZ cord-292657-gq3965se 174 5 the the DT cord-292657-gq3965se 174 6 important important JJ cord-292657-gq3965se 174 7 factor factor NN cord-292657-gq3965se 174 8 for for IN cord-292657-gq3965se 174 9 the the DT cord-292657-gq3965se 174 10 COVID-19 covid-19 JJ cord-292657-gq3965se 174 11 host host NN cord-292657-gq3965se 174 12 - - HYPH cord-292657-gq3965se 174 13 pathogenic pathogenic JJ cord-292657-gq3965se 174 14 interaction interaction NN cord-292657-gq3965se 174 15 establishment establishment NN cord-292657-gq3965se 174 16 where where WRB cord-292657-gq3965se 174 17 the the DT cord-292657-gq3965se 174 18 molecular molecular JJ cord-292657-gq3965se 174 19 evolution evolution NN cord-292657-gq3965se 174 20 happens happen VBZ cord-292657-gq3965se 174 21 . . . cord-292657-gq3965se 175 1 The the DT cord-292657-gq3965se 175 2 rapid rapid JJ cord-292657-gq3965se 175 3 host host NN cord-292657-gq3965se 175 4 body body NN cord-292657-gq3965se 175 5 changing change VBG cord-292657-gq3965se 175 6 pattern pattern NN cord-292657-gq3965se 175 7 helps help VBZ cord-292657-gq3965se 175 8 the the DT cord-292657-gq3965se 175 9 virus virus NN cord-292657-gq3965se 175 10 to to TO cord-292657-gq3965se 175 11 be be VB cord-292657-gq3965se 175 12 continuously continuously RB cord-292657-gq3965se 175 13 exposed expose VBN cord-292657-gq3965se 175 14 to to IN cord-292657-gq3965se 175 15 new new JJ cord-292657-gq3965se 175 16 environmental environmental JJ cord-292657-gq3965se 175 17 conditions condition NNS cord-292657-gq3965se 175 18 , , , cord-292657-gq3965se 175 19 which which WDT cord-292657-gq3965se 175 20 creates create VBZ cord-292657-gq3965se 175 21 selective selective JJ cord-292657-gq3965se 175 22 pressure pressure NN cord-292657-gq3965se 175 23 to to IN cord-292657-gq3965se 175 24 the the DT cord-292657-gq3965se 175 25 virus virus NN cord-292657-gq3965se 175 26 . . . cord-292657-gq3965se 176 1 In in IN cord-292657-gq3965se 176 2 order order NN cord-292657-gq3965se 176 3 to to TO cord-292657-gq3965se 176 4 struggle struggle VB cord-292657-gq3965se 176 5 for for IN cord-292657-gq3965se 176 6 existence existence NN cord-292657-gq3965se 176 7 and and CC cord-292657-gq3965se 176 8 infection infection NN cord-292657-gq3965se 176 9 establishment establishment NN cord-292657-gq3965se 176 10 inside inside IN cord-292657-gq3965se 176 11 host host NN cord-292657-gq3965se 176 12 body body NN cord-292657-gq3965se 176 13 , , , cord-292657-gq3965se 176 14 the the DT cord-292657-gq3965se 176 15 virus virus NN cord-292657-gq3965se 176 16 undergo undergo VBP cord-292657-gq3965se 176 17 through through IN cord-292657-gq3965se 176 18 several several JJ cord-292657-gq3965se 176 19 genetic genetic JJ cord-292657-gq3965se 176 20 manipulations manipulation NNS cord-292657-gq3965se 176 21 and and CC cord-292657-gq3965se 176 22 achieve achieve VB cord-292657-gq3965se 176 23 its -PRON- PRP$ cord-292657-gq3965se 176 24 mutated mutate VBN cord-292657-gq3965se 176 25 characters character NNS cord-292657-gq3965se 176 26 . . . cord-292657-gq3965se 177 1 Then then RB cord-292657-gq3965se 177 2 genetically genetically RB cord-292657-gq3965se 177 3 close close JJ cord-292657-gq3965se 177 4 different different JJ cord-292657-gq3965se 177 5 subtypes subtype NNS cord-292657-gq3965se 177 6 of of IN cord-292657-gq3965se 177 7 SARS SARS NNP cord-292657-gq3965se 177 8 - - HYPH cord-292657-gq3965se 177 9 CoV-2 CoV-2 NNP cord-292657-gq3965se 177 10 develops develop VBZ cord-292657-gq3965se 177 11 unique unique JJ cord-292657-gq3965se 177 12 spike spike NN cord-292657-gq3965se 177 13 protein protein NN cord-292657-gq3965se 177 14 receptor receptor NN cord-292657-gq3965se 177 15 binding bind VBG cord-292657-gq3965se 177 16 domain domain NN cord-292657-gq3965se 177 17 with with IN cord-292657-gq3965se 177 18 high high JJ cord-292657-gq3965se 177 19 degree degree NN cord-292657-gq3965se 177 20 of of IN cord-292657-gq3965se 177 21 receptor receptor NN cord-292657-gq3965se 177 22 binding bind VBG cord-292657-gq3965se 177 23 property property NN cord-292657-gq3965se 177 24 to to IN cord-292657-gq3965se 177 25 human human JJ cord-292657-gq3965se 177 26 cells cell NNS cord-292657-gq3965se 177 27 and and CC cord-292657-gq3965se 177 28 adapt adapt VB cord-292657-gq3965se 177 29 itself -PRON- PRP cord-292657-gq3965se 177 30 to to TO cord-292657-gq3965se 177 31 fit fit VB cord-292657-gq3965se 177 32 the the DT cord-292657-gq3965se 177 33 character character NN cord-292657-gq3965se 177 34 inside inside IN cord-292657-gq3965se 177 35 the the DT cord-292657-gq3965se 177 36 host host NN cord-292657-gq3965se 177 37 body body NN cord-292657-gq3965se 177 38 . . . cord-292657-gq3965se 178 1 Ultimately ultimately RB cord-292657-gq3965se 178 2 by by IN cord-292657-gq3965se 178 3 the the DT cord-292657-gq3965se 178 4 action action NN cord-292657-gq3965se 178 5 of of IN cord-292657-gq3965se 178 6 natural natural JJ cord-292657-gq3965se 178 7 selection selection NN cord-292657-gq3965se 178 8 , , , cord-292657-gq3965se 178 9 specific specific JJ cord-292657-gq3965se 178 10 host host NN cord-292657-gq3965se 178 11 - - HYPH cord-292657-gq3965se 178 12 pathogen pathogen NN cord-292657-gq3965se 178 13 interaction interaction NN cord-292657-gq3965se 178 14 happens happen VBZ cord-292657-gq3965se 178 15 where where WRB cord-292657-gq3965se 178 16 the the DT cord-292657-gq3965se 178 17 virus virus NN cord-292657-gq3965se 178 18 can can MD cord-292657-gq3965se 178 19 establish establish VB cord-292657-gq3965se 178 20 the the DT cord-292657-gq3965se 178 21 infection infection NN cord-292657-gq3965se 178 22 . . . cord-292657-gq3965se 179 1 The the DT cord-292657-gq3965se 179 2 external external JJ cord-292657-gq3965se 179 3 environment environment NN cord-292657-gq3965se 179 4 acts act VBZ cord-292657-gq3965se 179 5 as as IN cord-292657-gq3965se 179 6 intermediate intermediate JJ cord-292657-gq3965se 179 7 player player NN cord-292657-gq3965se 179 8 in in IN cord-292657-gq3965se 179 9 between between IN cord-292657-gq3965se 179 10 one one CD cord-292657-gq3965se 179 11 host host NN cord-292657-gq3965se 179 12 to to IN cord-292657-gq3965se 179 13 another another DT cord-292657-gq3965se 179 14 , , , cord-292657-gq3965se 179 15 by by IN cord-292657-gq3965se 179 16 providing provide VBG cord-292657-gq3965se 179 17 suitable suitable JJ cord-292657-gq3965se 179 18 environment environment NN cord-292657-gq3965se 179 19 for for IN cord-292657-gq3965se 179 20 stability stability NN cord-292657-gq3965se 179 21 and and CC cord-292657-gq3965se 179 22 survival survival NN cord-292657-gq3965se 179 23 for for IN cord-292657-gq3965se 179 24 SARS SARS NNP cord-292657-gq3965se 179 25 - - HYPH cord-292657-gq3965se 179 26 CoV-2 CoV-2 NNP cord-292657-gq3965se 179 27 outside outside IN cord-292657-gq3965se 179 28 its -PRON- PRP$ cord-292657-gq3965se 179 29 host host NN cord-292657-gq3965se 179 30 body body NN cord-292657-gq3965se 179 31 resulting result VBG cord-292657-gq3965se 179 32 high high JJ cord-292657-gq3965se 179 33 viability viability NN cord-292657-gq3965se 179 34 and and CC cord-292657-gq3965se 179 35 higher high JJR cord-292657-gq3965se 179 36 transmissibility transmissibility NN cord-292657-gq3965se 179 37 compared compare VBN cord-292657-gq3965se 179 38 to to IN cord-292657-gq3965se 179 39 other other JJ cord-292657-gq3965se 179 40 corona corona NN cord-292657-gq3965se 179 41 virus virus NN cord-292657-gq3965se 179 42 . . . cord-292657-gq3965se 180 1 It -PRON- PRP cord-292657-gq3965se 180 2 has have VBZ cord-292657-gq3965se 180 3 been be VBN cord-292657-gq3965se 180 4 reported report VBN cord-292657-gq3965se 180 5 that that IN cord-292657-gq3965se 180 6 the the DT cord-292657-gq3965se 180 7 external external JJ cord-292657-gq3965se 180 8 environment environment NN cord-292657-gq3965se 180 9 also also RB cord-292657-gq3965se 180 10 interacts interact VBZ cord-292657-gq3965se 180 11 with with IN cord-292657-gq3965se 180 12 the the DT cord-292657-gq3965se 180 13 host host NN cord-292657-gq3965se 180 14 body body NN cord-292657-gq3965se 180 15 environment environment NN cord-292657-gq3965se 180 16 and and CC cord-292657-gq3965se 180 17 helps help VBZ cord-292657-gq3965se 180 18 the the DT cord-292657-gq3965se 180 19 stability stability NN cord-292657-gq3965se 180 20 of of IN cord-292657-gq3965se 180 21 the the DT cord-292657-gq3965se 180 22 virus virus NN cord-292657-gq3965se 180 23 inside inside IN cord-292657-gq3965se 180 24 the the DT cord-292657-gq3965se 180 25 host host NN cord-292657-gq3965se 180 26 body body NN cord-292657-gq3965se 180 27 system system NN cord-292657-gq3965se 180 28 and and CC cord-292657-gq3965se 180 29 its -PRON- PRP$ cord-292657-gq3965se 180 30 infectivity infectivity NN cord-292657-gq3965se 180 31 . . . cord-292657-gq3965se 181 1 Changing change VBG cord-292657-gq3965se 181 2 temperature temperature NN cord-292657-gq3965se 181 3 and and CC cord-292657-gq3965se 181 4 relative relative JJ cord-292657-gq3965se 181 5 humidity humidity NN cord-292657-gq3965se 181 6 contributes contribute VBZ cord-292657-gq3965se 181 7 to to IN cord-292657-gq3965se 181 8 the the DT cord-292657-gq3965se 181 9 degree degree NN cord-292657-gq3965se 181 10 of of IN cord-292657-gq3965se 181 11 host host NN cord-292657-gq3965se 181 12 susceptibility susceptibility NN cord-292657-gq3965se 181 13 to to IN cord-292657-gq3965se 181 14 a a DT cord-292657-gq3965se 181 15 certain certain JJ cord-292657-gq3965se 181 16 pathogen pathogen NN cord-292657-gq3965se 181 17 , , , cord-292657-gq3965se 181 18 pathogen pathogen NN cord-292657-gq3965se 181 19 infiltration infiltration NN cord-292657-gq3965se 181 20 and and CC cord-292657-gq3965se 181 21 survival survival NN cord-292657-gq3965se 181 22 inside inside IN cord-292657-gq3965se 181 23 the the DT cord-292657-gq3965se 181 24 host host NN cord-292657-gq3965se 181 25 body body NN cord-292657-gq3965se 181 26 [ [ -LRB- cord-292657-gq3965se 181 27 22 22 CD cord-292657-gq3965se 181 28 ] ] -RRB- cord-292657-gq3965se 181 29 . . . cord-292657-gq3965se 182 1 Thus thus RB cord-292657-gq3965se 182 2 the the DT cord-292657-gq3965se 182 3 outcomes outcome NNS cord-292657-gq3965se 182 4 from from IN cord-292657-gq3965se 182 5 the the DT cord-292657-gq3965se 182 6 whole whole JJ cord-292657-gq3965se 182 7 study study NN cord-292657-gq3965se 182 8 will will MD cord-292657-gq3965se 182 9 help help VB cord-292657-gq3965se 182 10 to to TO cord-292657-gq3965se 182 11 understand understand VB cord-292657-gq3965se 182 12 the the DT cord-292657-gq3965se 182 13 sudden sudden JJ cord-292657-gq3965se 182 14 emergence emergence NN cord-292657-gq3965se 182 15 of of IN cord-292657-gq3965se 182 16 COVID-19 covid-19 JJ cord-292657-gq3965se 182 17 pandemic pandemic NN cord-292657-gq3965se 182 18 and and CC cord-292657-gq3965se 182 19 its -PRON- PRP$ cord-292657-gq3965se 182 20 character character NN cord-292657-gq3965se 182 21 . . . cord-292657-gq3965se 183 1 The the DT cord-292657-gq3965se 183 2 findings finding NNS cord-292657-gq3965se 183 3 emphasize emphasize VBP cord-292657-gq3965se 183 4 to to TO cord-292657-gq3965se 183 5 consider consider VB cord-292657-gq3965se 183 6 the the DT cord-292657-gq3965se 183 7 interactive interactive JJ cord-292657-gq3965se 183 8 role role NN cord-292657-gq3965se 183 9 of of IN cord-292657-gq3965se 183 10 both both DT cord-292657-gq3965se 183 11 of of IN cord-292657-gq3965se 183 12 the the DT cord-292657-gq3965se 183 13 two two CD cord-292657-gq3965se 183 14 environments environment NNS cord-292657-gq3965se 183 15 , , , cord-292657-gq3965se 183 16 the the DT cord-292657-gq3965se 183 17 host host NN cord-292657-gq3965se 183 18 body body NN cord-292657-gq3965se 183 19 environment environment NN cord-292657-gq3965se 183 20 and and CC cord-292657-gq3965se 183 21 the the DT cord-292657-gq3965se 183 22 external external JJ cord-292657-gq3965se 183 23 environment environment NN cord-292657-gq3965se 183 24 as as IN cord-292657-gq3965se 183 25 the the DT cord-292657-gq3965se 183 26 source source NN cord-292657-gq3965se 183 27 of of IN cord-292657-gq3965se 183 28 genetic genetic JJ cord-292657-gq3965se 183 29 evolution evolution NN cord-292657-gq3965se 183 30 of of IN cord-292657-gq3965se 183 31 emerging emerge VBG cord-292657-gq3965se 183 32 viral viral JJ cord-292657-gq3965se 183 33 diseases disease NNS cord-292657-gq3965se 183 34 and and CC cord-292657-gq3965se 183 35 its -PRON- PRP$ cord-292657-gq3965se 183 36 control control NN cord-292657-gq3965se 183 37 . . . cord-292657-gq3965se 183 38 _SP cord-292657-gq3965se 184 1 History history NN cord-292657-gq3965se 184 2 of of IN cord-292657-gq3965se 184 3 highly highly RB cord-292657-gq3965se 184 4 pathogenic pathogenic JJ cord-292657-gq3965se 184 5 avian avian JJ cord-292657-gq3965se 184 6 influenza influenza NN cord-292657-gq3965se 184 7 . . . cord-292657-gq3965se 185 1 Revue Revue NNP cord-292657-gq3965se 185 2 scientifique scientifique FW cord-292657-gq3965se 185 3 et et FW cord-292657-gq3965se 185 4 technique technique NN cord-292657-gq3965se 185 5 ( ( -LRB- cord-292657-gq3965se 185 6 International International NNP cord-292657-gq3965se 185 7 Office Office NNP cord-292657-gq3965se 185 8 of of IN cord-292657-gq3965se 185 9 Epizootics Epizootics NNP cord-292657-gq3965se 185 10 ) ) -RRB- cord-292657-gq3965se 186 1 The the DT cord-292657-gq3965se 186 2 proximal proximal JJ cord-292657-gq3965se 186 3 origin origin NN cord-292657-gq3965se 186 4 of of IN cord-292657-gq3965se 186 5 SARS SARS NNP cord-292657-gq3965se 186 6 - - HYPH cord-292657-gq3965se 186 7 CoV-2 CoV-2 NNP cord-292657-gq3965se 186 8 Comparative comparative JJ cord-292657-gq3965se 186 9 genetic genetic JJ cord-292657-gq3965se 186 10 analysis analysis NN cord-292657-gq3965se 186 11 of of IN cord-292657-gq3965se 186 12 the the DT cord-292657-gq3965se 186 13 novel novel JJ cord-292657-gq3965se 186 14 coronavirus coronavirus NN cord-292657-gq3965se 186 15 ( ( -LRB- cord-292657-gq3965se 186 16 2019-nCoV 2019-ncov CD cord-292657-gq3965se 186 17 / / SYM cord-292657-gq3965se 186 18 SARS SARS NNP cord-292657-gq3965se 186 19 - - HYPH cord-292657-gq3965se 186 20 CoV-2 CoV-2 NNP cord-292657-gq3965se 186 21 ) ) -RRB- cord-292657-gq3965se 186 22 receptor receptor NN cord-292657-gq3965se 186 23 ACE2 ACE2 NNP cord-292657-gq3965se 186 24 in in IN cord-292657-gq3965se 186 25 different different JJ cord-292657-gq3965se 186 26 populations population NNS cord-292657-gq3965se 186 27 Effects effect NNS cord-292657-gq3965se 186 28 of of IN cord-292657-gq3965se 186 29 air air NN cord-292657-gq3965se 186 30 temperature temperature NN cord-292657-gq3965se 186 31 and and CC cord-292657-gq3965se 186 32 relative relative JJ cord-292657-gq3965se 186 33 humidity humidity NN cord-292657-gq3965se 186 34 on on IN cord-292657-gq3965se 186 35 coronavirus coronavirus NN cord-292657-gq3965se 186 36 survival survival NN cord-292657-gq3965se 186 37 on on IN cord-292657-gq3965se 186 38 surfaces surface NNS cord-292657-gq3965se 186 39 Nature nature NN cord-292657-gq3965se 186 40 , , , cord-292657-gq3965se 186 41 nurture nurture VB cord-292657-gq3965se 186 42 and and CC cord-292657-gq3965se 186 43 human human JJ cord-292657-gq3965se 186 44 disease disease NN cord-292657-gq3965se 187 1 The the DT cord-292657-gq3965se 187 2 presence presence NN cord-292657-gq3965se 187 3 of of IN cord-292657-gq3965se 187 4 SARS SARS NNP cord-292657-gq3965se 187 5 - - HYPH cord-292657-gq3965se 187 6 CoV-2 CoV-2 NNP cord-292657-gq3965se 187 7 RNA RNA NNP cord-292657-gq3965se 187 8 in in IN cord-292657-gq3965se 187 9 feces fece NNS cord-292657-gq3965se 187 10 of of IN cord-292657-gq3965se 187 11 COVID-19 covid-19 CD cord-292657-gq3965se 187 12 patients patient NNS cord-292657-gq3965se 187 13 Molecular molecular JJ cord-292657-gq3965se 187 14 evolution evolution NN cord-292657-gq3965se 187 15 of of IN cord-292657-gq3965se 187 16 the the DT cord-292657-gq3965se 187 17 SARS SARS NNP cord-292657-gq3965se 187 18 coronavirus coronavirus NN cord-292657-gq3965se 187 19 during during IN cord-292657-gq3965se 187 20 the the DT cord-292657-gq3965se 187 21 course course NN cord-292657-gq3965se 187 22 of of IN cord-292657-gq3965se 187 23 the the DT cord-292657-gq3965se 187 24 SARS SARS NNP cord-292657-gq3965se 187 25 epidemic epidemic NN cord-292657-gq3965se 187 26 in in IN cord-292657-gq3965se 187 27 China China NNP cord-292657-gq3965se 187 28 Origin Origin NNP cord-292657-gq3965se 187 29 and and CC cord-292657-gq3965se 187 30 evolution evolution NN cord-292657-gq3965se 187 31 of of IN cord-292657-gq3965se 187 32 pathogenic pathogenic JJ cord-292657-gq3965se 187 33 coronaviruses coronaviruse NNS cord-292657-gq3965se 187 34 Phylogenetic Phylogenetic NNP cord-292657-gq3965se 187 35 network network NN cord-292657-gq3965se 187 36 analysis analysis NN cord-292657-gq3965se 187 37 of of IN cord-292657-gq3965se 187 38 SARS SARS NNP cord-292657-gq3965se 187 39 - - HYPH cord-292657-gq3965se 187 40 CoV-2 CoV-2 NNP cord-292657-gq3965se 187 41 genomes genome NNS cord-292657-gq3965se 187 42 Bat Bat NNP cord-292657-gq3965se 187 43 origin origin NN cord-292657-gq3965se 187 44 of of IN cord-292657-gq3965se 187 45 human human JJ cord-292657-gq3965se 187 46 coronaviruses coronaviruse NNS cord-292657-gq3965se 187 47 Influenza Influenza NNP cord-292657-gq3965se 187 48 virus virus NN cord-292657-gq3965se 187 49 infectivity infectivity NN cord-292657-gq3965se 187 50 is be VBZ cord-292657-gq3965se 187 51 retained retain VBN cord-292657-gq3965se 187 52 in in IN cord-292657-gq3965se 187 53 aerosols aerosol NNS cord-292657-gq3965se 187 54 and and CC cord-292657-gq3965se 187 55 droplets droplet NNS cord-292657-gq3965se 187 56 independent independent JJ cord-292657-gq3965se 187 57 of of IN cord-292657-gq3965se 187 58 relative relative JJ cord-292657-gq3965se 187 59 humidity humidity NN cord-292657-gq3965se 187 60 Effect effect NN cord-292657-gq3965se 187 61 of of IN cord-292657-gq3965se 187 62 host host NN cord-292657-gq3965se 187 63 species specie NNS cord-292657-gq3965se 187 64 on on IN cord-292657-gq3965se 187 65 the the DT cord-292657-gq3965se 187 66 distribution distribution NN cord-292657-gq3965se 187 67 of of IN cord-292657-gq3965se 187 68 mutational mutational JJ cord-292657-gq3965se 187 69 fitness fitness NN cord-292657-gq3965se 187 70 effects effect NNS cord-292657-gq3965se 187 71 for for IN cord-292657-gq3965se 187 72 an an DT cord-292657-gq3965se 187 73 RNA RNA NNP cord-292657-gq3965se 187 74 virus virus NN cord-292657-gq3965se 187 75 Molecular molecular JJ cord-292657-gq3965se 187 76 evolution evolution NN cord-292657-gq3965se 187 77 of of IN cord-292657-gq3965se 187 78 MERS MERS NNP cord-292657-gq3965se 187 79 coronavirus coronavirus NN cord-292657-gq3965se 187 80 : : : cord-292657-gq3965se 187 81 dromedaries dromedary NNS cord-292657-gq3965se 187 82 as as IN cord-292657-gq3965se 187 83 a a DT cord-292657-gq3965se 187 84 recent recent JJ cord-292657-gq3965se 187 85 intermediate intermediate JJ cord-292657-gq3965se 187 86 host host NN cord-292657-gq3965se 187 87 or or CC cord-292657-gq3965se 187 88 longtime longtime JJ cord-292657-gq3965se 187 89 animal animal NN cord-292657-gq3965se 187 90 reservoir reservoir NN cord-292657-gq3965se 187 91 ? ? . cord-292657-gq3965se 188 1 Adaptive adaptive JJ cord-292657-gq3965se 188 2 evolution evolution NN cord-292657-gq3965se 188 3 of of IN cord-292657-gq3965se 188 4 MERS MERS NNP cord-292657-gq3965se 188 5 - - HYPH cord-292657-gq3965se 188 6 CoV CoV NNP cord-292657-gq3965se 188 7 to to IN cord-292657-gq3965se 188 8 species species NN cord-292657-gq3965se 188 9 variation variation NN cord-292657-gq3965se 188 10 in in IN cord-292657-gq3965se 188 11 DPP4 DPP4 NNP cord-292657-gq3965se 188 12 Receptor Receptor NNP cord-292657-gq3965se 188 13 recognition recognition NN cord-292657-gq3965se 188 14 mechanisms mechanism NNS cord-292657-gq3965se 188 15 of of IN cord-292657-gq3965se 188 16 coronaviruses coronaviruse NNS cord-292657-gq3965se 188 17 : : : cord-292657-gq3965se 188 18 a a DT cord-292657-gq3965se 188 19 decade decade NN cord-292657-gq3965se 188 20 of of IN cord-292657-gq3965se 188 21 structural structural JJ cord-292657-gq3965se 188 22 studies study NNS cord-292657-gq3965se 188 23 Emergence Emergence NNP cord-292657-gq3965se 188 24 of of IN cord-292657-gq3965se 188 25 SARS SARS NNP cord-292657-gq3965se 188 26 - - HYPH cord-292657-gq3965se 188 27 CoV-2 CoV-2 NNP cord-292657-gq3965se 188 28 through through IN cord-292657-gq3965se 188 29 recombination recombination NN cord-292657-gq3965se 188 30 and and CC cord-292657-gq3965se 188 31 strong strong JJ cord-292657-gq3965se 188 32 purifying purifying NN cord-292657-gq3965se 188 33 selection selection NN cord-292657-gq3965se 189 1 The the DT cord-292657-gq3965se 189 2 consequences consequence NNS cord-292657-gq3965se 189 3 of of IN cord-292657-gq3965se 189 4 human human JJ cord-292657-gq3965se 189 5 actions action NNS cord-292657-gq3965se 189 6 on on IN cord-292657-gq3965se 189 7 risks risk NNS cord-292657-gq3965se 189 8 for for IN cord-292657-gq3965se 189 9 infectious infectious JJ cord-292657-gq3965se 189 10 diseases disease NNS cord-292657-gq3965se 189 11 : : : cord-292657-gq3965se 189 12 a a DT cord-292657-gq3965se 189 13 review review NN cord-292657-gq3965se 189 14 SARS SARS NNP cord-292657-gq3965se 189 15 - - HYPH cord-292657-gq3965se 189 16 CoV-2 CoV-2 NNP cord-292657-gq3965se 189 17 in in IN cord-292657-gq3965se 189 18 wastewater wastewater NN cord-292657-gq3965se 189 19 : : : cord-292657-gq3965se 189 20 potential potential JJ cord-292657-gq3965se 189 21 health health NN cord-292657-gq3965se 189 22 risk risk NN cord-292657-gq3965se 189 23 , , , cord-292657-gq3965se 189 24 but but CC cord-292657-gq3965se 189 25 also also RB cord-292657-gq3965se 189 26 data data VBZ cord-292657-gq3965se 189 27 source source NN cord-292657-gq3965se 189 28 Evolutionary evolutionary JJ cord-292657-gq3965se 189 29 potential potential NN cord-292657-gq3965se 189 30 of of IN cord-292657-gq3965se 189 31 an an DT cord-292657-gq3965se 189 32 RNA RNA NNP cord-292657-gq3965se 189 33 virus virus NN cord-292657-gq3965se 189 34 Trypsin Trypsin NNP cord-292657-gq3965se 189 35 treatment treatment NN cord-292657-gq3965se 189 36 unlocks unlock VBZ cord-292657-gq3965se 189 37 barrier barrier NN cord-292657-gq3965se 189 38 for for IN cord-292657-gq3965se 189 39 zoonotic zoonotic JJ cord-292657-gq3965se 189 40 bat bat NN cord-292657-gq3965se 189 41 coronavirus coronavirus NN cord-292657-gq3965se 189 42 infection infection NN cord-292657-gq3965se 189 43 Genetic genetic JJ cord-292657-gq3965se 189 44 diversity diversity NN cord-292657-gq3965se 189 45 and and CC cord-292657-gq3965se 189 46 evolution evolution NN cord-292657-gq3965se 189 47 of of IN cord-292657-gq3965se 189 48 SARS SARS NNP cord-292657-gq3965se 189 49 - - HYPH cord-292657-gq3965se 189 50 CoV-2 CoV-2 NNP cord-292657-gq3965se 189 51 Changes change NNS cord-292657-gq3965se 189 52 in in IN cord-292657-gq3965se 189 53 temperature temperature NN cord-292657-gq3965se 189 54 alter alter VB cord-292657-gq3965se 189 55 the the DT cord-292657-gq3965se 189 56 potential potential JJ cord-292657-gq3965se 189 57 outcomes outcome NNS cord-292657-gq3965se 189 58 of of IN cord-292657-gq3965se 189 59 virus virus NN cord-292657-gq3965se 189 60 host host NN cord-292657-gq3965se 189 61 shifts shift VBZ cord-292657-gq3965se 189 62 Pathways pathway NNS cord-292657-gq3965se 189 63 of of IN cord-292657-gq3965se 189 64 cross cross JJ cord-292657-gq3965se 189 65 - - JJ cord-292657-gq3965se 189 66 species species JJ cord-292657-gq3965se 189 67 transmission transmission NN cord-292657-gq3965se 189 68 of of IN cord-292657-gq3965se 189 69 synthetically synthetically RB cord-292657-gq3965se 189 70 reconstructed reconstruct VBN cord-292657-gq3965se 189 71 zoonotic zoonotic JJ cord-292657-gq3965se 189 72 severe severe JJ cord-292657-gq3965se 189 73 acute acute JJ cord-292657-gq3965se 189 74 respiratory respiratory JJ cord-292657-gq3965se 189 75 syndrome syndrome NN cord-292657-gq3965se 189 76 coronavirus coronavirus NN cord-292657-gq3965se 189 77 Animal Animal NNP cord-292657-gq3965se 189 78 virus virus NN cord-292657-gq3965se 189 79 ecology ecology NN cord-292657-gq3965se 189 80 and and CC cord-292657-gq3965se 189 81 evolution evolution NN cord-292657-gq3965se 189 82 are be VBP cord-292657-gq3965se 189 83 shaped shape VBN cord-292657-gq3965se 189 84 by by IN cord-292657-gq3965se 189 85 the the DT cord-292657-gq3965se 189 86 virus virus NN cord-292657-gq3965se 189 87 host host NN cord-292657-gq3965se 189 88 - - HYPH cord-292657-gq3965se 189 89 body body NN cord-292657-gq3965se 189 90 infiltration infiltration NN cord-292657-gq3965se 189 91 and and CC cord-292657-gq3965se 189 92 colonization colonization NN cord-292657-gq3965se 189 93 pattern pattern NN cord-292657-gq3965se 189 94 . . . cord-292657-gq3965se 190 1 bioRxiv biorxiv RB cord-292657-gq3965se 191 1 The the DT cord-292657-gq3965se 191 2 evolution evolution NN cord-292657-gq3965se 191 3 of of IN cord-292657-gq3965se 191 4 covert covert JJ cord-292657-gq3965se 191 5 , , , cord-292657-gq3965se 191 6 silent silent JJ cord-292657-gq3965se 191 7 infection infection NN cord-292657-gq3965se 191 8 as as IN cord-292657-gq3965se 191 9 a a DT cord-292657-gq3965se 191 10 parasite parasite NN cord-292657-gq3965se 191 11 strategy strategy NN cord-292657-gq3965se 191 12 Epidemiology epidemiology NN cord-292657-gq3965se 191 13 , , , cord-292657-gq3965se 191 14 genetic genetic JJ cord-292657-gq3965se 191 15 recombination recombination NN cord-292657-gq3965se 191 16 , , , cord-292657-gq3965se 191 17 and and CC cord-292657-gq3965se 191 18 pathogenesis pathogenesis NN cord-292657-gq3965se 191 19 of of IN cord-292657-gq3965se 191 20 coronaviruses coronaviruse NNS cord-292657-gq3965se 191 21 Aerosol Aerosol NNP cord-292657-gq3965se 191 22 and and CC cord-292657-gq3965se 191 23 surface surface NN cord-292657-gq3965se 191 24 stability stability NN cord-292657-gq3965se 191 25 of of IN cord-292657-gq3965se 191 26 SARS SARS NNP cord-292657-gq3965se 191 27 - - HYPH cord-292657-gq3965se 191 28 CoV-2 CoV-2 NNP cord-292657-gq3965se 191 29 as as IN cord-292657-gq3965se 191 30 compared compare VBN cord-292657-gq3965se 191 31 with with IN cord-292657-gq3965se 191 32 SARS SARS NNP cord-292657-gq3965se 191 33 - - HYPH cord-292657-gq3965se 191 34 CoV-1 CoV-1 NNP cord-292657-gq3965se 191 35 Viruses virus NNS cord-292657-gq3965se 191 36 switch switch VBP cord-292657-gq3965se 191 37 hosts host NNS cord-292657-gq3965se 191 38 to to TO cord-292657-gq3965se 191 39 evolve evolve VB cord-292657-gq3965se 191 40 Structure Structure NNP cord-292657-gq3965se 191 41 , , , cord-292657-gq3965se 191 42 function function NN cord-292657-gq3965se 191 43 , , , cord-292657-gq3965se 191 44 and and CC cord-292657-gq3965se 191 45 antigenicity antigenicity NN cord-292657-gq3965se 191 46 of of IN cord-292657-gq3965se 191 47 the the DT cord-292657-gq3965se 191 48 SARS SARS NNP cord-292657-gq3965se 191 49 - - HYPH cord-292657-gq3965se 191 50 CoV-2 CoV-2 NNP cord-292657-gq3965se 191 51 spike spike NN cord-292657-gq3965se 191 52 glycoprotein glycoprotein NN cord-292657-gq3965se 191 53 Detection detection NN cord-292657-gq3965se 191 54 of of IN cord-292657-gq3965se 191 55 SARS SARS NNP cord-292657-gq3965se 191 56 - - HYPH cord-292657-gq3965se 191 57 CoV-2 CoV-2 NNP cord-292657-gq3965se 191 58 in in IN cord-292657-gq3965se 191 59 different different JJ cord-292657-gq3965se 191 60 types type NNS cord-292657-gq3965se 191 61 of of IN cord-292657-gq3965se 191 62 clinical clinical JJ cord-292657-gq3965se 191 63 specimens specimen NNS cord-292657-gq3965se 191 64 Social social JJ cord-292657-gq3965se 191 65 and and CC cord-292657-gq3965se 191 66 environmental environmental JJ cord-292657-gq3965se 191 67 risk risk NN cord-292657-gq3965se 191 68 factors factor NNS cord-292657-gq3965se 191 69 in in IN cord-292657-gq3965se 191 70 the the DT cord-292657-gq3965se 191 71 emergence emergence NN cord-292657-gq3965se 191 72 of of IN cord-292657-gq3965se 191 73 infectious infectious JJ cord-292657-gq3965se 191 74 diseases disease NNS cord-292657-gq3965se 192 1 A a DT cord-292657-gq3965se 192 2 new new JJ cord-292657-gq3965se 192 3 coronavirus coronavirus NN cord-292657-gq3965se 192 4 associated associate VBN cord-292657-gq3965se 192 5 with with IN cord-292657-gq3965se 192 6 human human JJ cord-292657-gq3965se 192 7 respiratory respiratory JJ cord-292657-gq3965se 192 8 disease disease NN cord-292657-gq3965se 192 9 in in IN cord-292657-gq3965se 192 10 China China NNP cord-292657-gq3965se 193 1 The the DT cord-292657-gq3965se 193 2 interaction interaction NN cord-292657-gq3965se 193 3 between between IN cord-292657-gq3965se 193 4 respiratory respiratory JJ cord-292657-gq3965se 193 5 pathogens pathogen NNS cord-292657-gq3965se 193 6 and and CC cord-292657-gq3965se 193 7 mucus mucus VB cord-292657-gq3965se 193 8 Pangolin Pangolin NNP cord-292657-gq3965se 193 9 homology homology NN cord-292657-gq3965se 193 10 associated associate VBN cord-292657-gq3965se 193 11 with with IN cord-292657-gq3965se 193 12 2019-nCoV 2019-ncov CD cord-292657-gq3965se 193 13 A a DT cord-292657-gq3965se 193 14 pneumonia pneumonia NN cord-292657-gq3965se 193 15 outbreak outbreak NN cord-292657-gq3965se 193 16 associated associate VBN cord-292657-gq3965se 193 17 with with IN cord-292657-gq3965se 193 18 a a DT cord-292657-gq3965se 193 19 new new JJ cord-292657-gq3965se 193 20 coronavirus coronavirus NN cord-292657-gq3965se 193 21 of of IN cord-292657-gq3965se 193 22 probable probable JJ cord-292657-gq3965se 193 23 bat bat NN cord-292657-gq3965se 193 24 origin origin NN cord-292657-gq3965se 193 25 Acknowledgements acknowledgement NNS cord-292657-gq3965se 194 1 We -PRON- PRP cord-292657-gq3965se 194 2 would would MD cord-292657-gq3965se 194 3 like like VB cord-292657-gq3965se 194 4 to to TO cord-292657-gq3965se 194 5 thank thank VB cord-292657-gq3965se 194 6 Mr. Mr. NNP cord-292657-gq3965se 194 7 Laltu Laltu NNP cord-292657-gq3965se 194 8 Hazra Hazra NNP cord-292657-gq3965se 194 9 , , , cord-292657-gq3965se 194 10 regarding regard VBG cord-292657-gq3965se 194 11 his -PRON- PRP$ cord-292657-gq3965se 194 12 general general JJ cord-292657-gq3965se 194 13 laboratory laboratory NN cord-292657-gq3965se 194 14 help help NN cord-292657-gq3965se 194 15 and and CC cord-292657-gq3965se 194 16 CSIR CSIR NNP cord-292657-gq3965se 194 17 for for IN cord-292657-gq3965se 194 18 their -PRON- PRP$ cord-292657-gq3965se 194 19 financial financial JJ cord-292657-gq3965se 194 20 assistance assistance NN cord-292657-gq3965se 194 21 by by IN cord-292657-gq3965se 194 22 CSIR CSIR NNP cord-292657-gq3965se 194 23 SRF SRF NNP cord-292657-gq3965se 194 24 fellowship fellowship NN cord-292657-gq3965se 194 25 for for IN cord-292657-gq3965se 194 26 PD PD NNP cord-292657-gq3965se 194 27 ( ( -LRB- cord-292657-gq3965se 194 28 Council Council NNP cord-292657-gq3965se 194 29 of of IN cord-292657-gq3965se 194 30 Scientific Scientific NNP cord-292657-gq3965se 194 31 and and CC cord-292657-gq3965se 194 32 Industrial Industrial NNP cord-292657-gq3965se 194 33 Research Research NNP cord-292657-gq3965se 194 34 , , , cord-292657-gq3965se 194 35 Govt Govt NNP cord-292657-gq3965se 194 36 . . . cord-292657-gq3965se 195 1 of of IN cord-292657-gq3965se 195 2 India India NNP cord-292657-gq3965se 195 3 , , , cord-292657-gq3965se 195 4 Senior Senior NNP cord-292657-gq3965se 195 5 Research Research NNP cord-292657-gq3965se 195 6 Fellowship Fellowship NNP cord-292657-gq3965se 195 7 ) ) -RRB- cord-292657-gq3965se 195 8 . . . cord-292657-gq3965se 196 1 TC TC NNP cord-292657-gq3965se 196 2 is be VBZ cord-292657-gq3965se 196 3 a a DT cord-292657-gq3965se 196 4 Fellow Fellow NNP cord-292657-gq3965se 196 5 of of IN cord-292657-gq3965se 196 6 Indian Indian NNP cord-292657-gq3965se 196 7 Virological Virological NNP cord-292657-gq3965se 196 8 Society Society NNP cord-292657-gq3965se 196 9 . . . cord-292657-gq3965se 197 1 The the DT cord-292657-gq3965se 197 2 authors author NNS cord-292657-gq3965se 197 3 also also RB cord-292657-gq3965se 197 4 thank thank VBP cord-292657-gq3965se 197 5 IIT IIT NNP cord-292657-gq3965se 197 6 Delhi Delhi NNP cord-292657-gq3965se 197 7 HPC hpc NN cord-292657-gq3965se 197 8 facility facility NN cord-292657-gq3965se 197 9 for for IN cord-292657-gq3965se 197 10 computational computational JJ cord-292657-gq3965se 197 11 resources resource NNS cord-292657-gq3965se 197 12 . . . cord-292657-gq3965se 198 1 Conflict conflict NN cord-292657-gq3965se 198 2 of of IN cord-292657-gq3965se 198 3 interest interest NN cord-292657-gq3965se 199 1 The the DT cord-292657-gq3965se 199 2 authors author NNS cord-292657-gq3965se 199 3 declare declare VBP cord-292657-gq3965se 199 4 that that IN cord-292657-gq3965se 199 5 they -PRON- PRP cord-292657-gq3965se 199 6 have have VBP cord-292657-gq3965se 199 7 no no DT cord-292657-gq3965se 199 8 conflict conflict NN cord-292657-gq3965se 199 9 of of IN cord-292657-gq3965se 199 10 interest interest NN cord-292657-gq3965se 199 11 . . .