id	sid	tid	token	lemma	pos
cord-288231-vg8bwed9	1	1	key	key	NN
cord-288231-vg8bwed9	1	2	:	:	:
cord-288231-vg8bwed9	2	1	cord-288231-vg8bwed9	cord-288231-vg8bwed9	JJ
cord-288231-vg8bwed9	2	2	authors	author	NNS
cord-288231-vg8bwed9	2	3	:	:	:
cord-288231-vg8bwed9	2	4	Haagmans	Haagmans	NNPS
cord-288231-vg8bwed9	2	5	,	,	,
cord-288231-vg8bwed9	2	6	Bart	Bart	NNP
cord-288231-vg8bwed9	2	7	L.	L.	NNP
cord-288231-vg8bwed9	2	8	;	;	:
cord-288231-vg8bwed9	2	9	Andeweg	Andeweg	NNP
cord-288231-vg8bwed9	2	10	,	,	,
cord-288231-vg8bwed9	2	11	Arno	Arno	NNP
cord-288231-vg8bwed9	2	12	C.	C.	NNP
cord-288231-vg8bwed9	2	13	;	;	:
cord-288231-vg8bwed9	2	14	Osterhaus	Osterhaus	NNP
cord-288231-vg8bwed9	2	15	,	,	,
cord-288231-vg8bwed9	2	16	Albert	Albert	NNP
cord-288231-vg8bwed9	2	17	D.	D.	NNP
cord-288231-vg8bwed9	2	18	M.	M.	NNP
cord-288231-vg8bwed9	2	19	E.	E.	NNP
cord-288231-vg8bwed9	2	20	title	title	NN
cord-288231-vg8bwed9	2	21	:	:	:
cord-288231-vg8bwed9	2	22	The	the	DT
cord-288231-vg8bwed9	2	23	Application	Application	NNP
cord-288231-vg8bwed9	2	24	of	of	IN
cord-288231-vg8bwed9	2	25	Genomics	Genomics	NNPS
cord-288231-vg8bwed9	2	26	to	to	IN
cord-288231-vg8bwed9	2	27	Emerging	Emerging	NNP
cord-288231-vg8bwed9	2	28	Zoonotic	Zoonotic	NNP
cord-288231-vg8bwed9	2	29	Viral	Viral	NNP
cord-288231-vg8bwed9	2	30	Diseases	Diseases	NNPS
cord-288231-vg8bwed9	2	31	date	date	NN
cord-288231-vg8bwed9	2	32	:	:	:
cord-288231-vg8bwed9	2	33	2009	2009	CD
cord-288231-vg8bwed9	2	34	-	-	SYM
cord-288231-vg8bwed9	2	35	10	10	CD
cord-288231-vg8bwed9	2	36	-	-	SYM
cord-288231-vg8bwed9	2	37	26	26	CD
cord-288231-vg8bwed9	2	38	journal	journal	NN
cord-288231-vg8bwed9	2	39	:	:	:
cord-288231-vg8bwed9	2	40	PLoS	PLoS	NNP
cord-288231-vg8bwed9	2	41	Pathog	Pathog	NNP
cord-288231-vg8bwed9	2	42	DOI	DOI	NNP
cord-288231-vg8bwed9	2	43	:	:	:
cord-288231-vg8bwed9	2	44	10.1371	10.1371	CD
cord-288231-vg8bwed9	2	45	/	/	SYM
cord-288231-vg8bwed9	2	46	journal.ppat.1000557	journal.ppat.1000557	NNP
cord-288231-vg8bwed9	2	47	sha	sha	NNP
cord-288231-vg8bwed9	2	48	:	:	:
cord-288231-vg8bwed9	2	49	faced14dbb3af799525a67f97bd6d5b904a365e3	faced14dbb3af799525a67f97bd6d5b904a365e3	XX
cord-288231-vg8bwed9	2	50	doc_id	doc_id	CD
cord-288231-vg8bwed9	2	51	:	:	:
cord-288231-vg8bwed9	3	1	288231	288231	CD
cord-288231-vg8bwed9	3	2	cord_uid	cord_uid	NNS
cord-288231-vg8bwed9	3	3	:	:	:
cord-288231-vg8bwed9	4	1	vg8bwed9	vg8bwed9	NNP
cord-288231-vg8bwed9	4	2	Interspecies	Interspecies	NNP
cord-288231-vg8bwed9	4	3	transmission	transmission	NN
cord-288231-vg8bwed9	4	4	of	of	IN
cord-288231-vg8bwed9	4	5	pathogens	pathogen	NNS
cord-288231-vg8bwed9	4	6	may	may	MD
cord-288231-vg8bwed9	4	7	result	result	VB
cord-288231-vg8bwed9	4	8	in	in	IN
cord-288231-vg8bwed9	4	9	the	the	DT
cord-288231-vg8bwed9	4	10	emergence	emergence	NN
cord-288231-vg8bwed9	4	11	of	of	IN
cord-288231-vg8bwed9	4	12	new	new	JJ
cord-288231-vg8bwed9	4	13	infectious	infectious	JJ
cord-288231-vg8bwed9	4	14	diseases	disease	NNS
cord-288231-vg8bwed9	4	15	in	in	IN
cord-288231-vg8bwed9	4	16	humans	human	NNS
cord-288231-vg8bwed9	4	17	as	as	RB
cord-288231-vg8bwed9	4	18	well	well	RB
cord-288231-vg8bwed9	4	19	as	as	IN
cord-288231-vg8bwed9	4	20	in	in	IN
cord-288231-vg8bwed9	4	21	domestic	domestic	JJ
cord-288231-vg8bwed9	4	22	and	and	CC
cord-288231-vg8bwed9	4	23	wild	wild	JJ
cord-288231-vg8bwed9	4	24	animals	animal	NNS
cord-288231-vg8bwed9	4	25	.	.	.
cord-288231-vg8bwed9	5	1	Genomics	genomic	NNS
cord-288231-vg8bwed9	5	2	tools	tool	NNS
cord-288231-vg8bwed9	5	3	such	such	JJ
cord-288231-vg8bwed9	5	4	as	as	IN
cord-288231-vg8bwed9	5	5	high	high	JJ
cord-288231-vg8bwed9	5	6	-	-	HYPH
cord-288231-vg8bwed9	5	7	throughput	throughput	NN
cord-288231-vg8bwed9	5	8	sequencing	sequencing	NN
cord-288231-vg8bwed9	5	9	,	,	,
cord-288231-vg8bwed9	5	10	mRNA	mrna	NN
cord-288231-vg8bwed9	5	11	expression	expression	NN
cord-288231-vg8bwed9	5	12	profiling	profiling	NN
cord-288231-vg8bwed9	5	13	,	,	,
cord-288231-vg8bwed9	5	14	and	and	CC
cord-288231-vg8bwed9	5	15	microarray	microarray	NN
cord-288231-vg8bwed9	5	16	-	-	HYPH
cord-288231-vg8bwed9	5	17	based	base	VBN
cord-288231-vg8bwed9	5	18	analysis	analysis	NN
cord-288231-vg8bwed9	5	19	of	of	IN
cord-288231-vg8bwed9	5	20	single	single	JJ
cord-288231-vg8bwed9	5	21	nucleotide	nucleotide	JJ
cord-288231-vg8bwed9	5	22	polymorphisms	polymorphism	NNS
cord-288231-vg8bwed9	5	23	are	be	VBP
cord-288231-vg8bwed9	5	24	providing	provide	VBG
cord-288231-vg8bwed9	5	25	unprecedented	unprecedented	JJ
cord-288231-vg8bwed9	5	26	ways	way	NNS
cord-288231-vg8bwed9	5	27	to	to	TO
cord-288231-vg8bwed9	5	28	analyze	analyze	VB
cord-288231-vg8bwed9	5	29	the	the	DT
cord-288231-vg8bwed9	5	30	diversity	diversity	NN
cord-288231-vg8bwed9	5	31	of	of	IN
cord-288231-vg8bwed9	5	32	the	the	DT
cord-288231-vg8bwed9	5	33	genomes	genome	NNS
cord-288231-vg8bwed9	5	34	of	of	IN
cord-288231-vg8bwed9	5	35	emerging	emerge	VBG
cord-288231-vg8bwed9	5	36	pathogens	pathogen	NNS
cord-288231-vg8bwed9	5	37	as	as	RB
cord-288231-vg8bwed9	5	38	well	well	RB
cord-288231-vg8bwed9	5	39	as	as	IN
cord-288231-vg8bwed9	5	40	the	the	DT
cord-288231-vg8bwed9	5	41	molecular	molecular	JJ
cord-288231-vg8bwed9	5	42	basis	basis	NN
cord-288231-vg8bwed9	5	43	of	of	IN
cord-288231-vg8bwed9	5	44	the	the	DT
cord-288231-vg8bwed9	5	45	host	host	NN
cord-288231-vg8bwed9	5	46	response	response	NN
cord-288231-vg8bwed9	5	47	to	to	IN
cord-288231-vg8bwed9	5	48	them	-PRON-	PRP
cord-288231-vg8bwed9	5	49	.	.	.
cord-288231-vg8bwed9	6	1	By	by	IN
cord-288231-vg8bwed9	6	2	comparing	compare	VBG
cord-288231-vg8bwed9	6	3	and	and	CC
cord-288231-vg8bwed9	6	4	contrasting	contrast	VBG
cord-288231-vg8bwed9	6	5	the	the	DT
cord-288231-vg8bwed9	6	6	outcomes	outcome	NNS
cord-288231-vg8bwed9	6	7	of	of	IN
cord-288231-vg8bwed9	6	8	an	an	DT
cord-288231-vg8bwed9	6	9	emerging	emerge	VBG
cord-288231-vg8bwed9	6	10	infection	infection	NN
cord-288231-vg8bwed9	6	11	with	with	IN
cord-288231-vg8bwed9	6	12	those	those	DT
cord-288231-vg8bwed9	6	13	of	of	IN
cord-288231-vg8bwed9	6	14	closely	closely	RB
cord-288231-vg8bwed9	6	15	related	related	JJ
cord-288231-vg8bwed9	6	16	pathogens	pathogen	NNS
cord-288231-vg8bwed9	6	17	in	in	IN
cord-288231-vg8bwed9	6	18	different	different	JJ
cord-288231-vg8bwed9	6	19	but	but	CC
cord-288231-vg8bwed9	6	20	related	related	JJ
cord-288231-vg8bwed9	6	21	host	host	NN
cord-288231-vg8bwed9	6	22	species	specie	NNS
cord-288231-vg8bwed9	6	23	,	,	,
cord-288231-vg8bwed9	6	24	we	-PRON-	PRP
cord-288231-vg8bwed9	6	25	can	can	MD
cord-288231-vg8bwed9	6	26	further	further	RB
cord-288231-vg8bwed9	6	27	delineate	delineate	VB
cord-288231-vg8bwed9	6	28	the	the	DT
cord-288231-vg8bwed9	6	29	various	various	JJ
cord-288231-vg8bwed9	6	30	host	host	NN
cord-288231-vg8bwed9	6	31	pathways	pathway	NNS
cord-288231-vg8bwed9	6	32	determining	determine	VBG
cord-288231-vg8bwed9	6	33	the	the	DT
cord-288231-vg8bwed9	6	34	outcome	outcome	NN
cord-288231-vg8bwed9	6	35	of	of	IN
cord-288231-vg8bwed9	6	36	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	6	37	transmission	transmission	NN
cord-288231-vg8bwed9	6	38	and	and	CC
cord-288231-vg8bwed9	6	39	adaptation	adaptation	NN
cord-288231-vg8bwed9	6	40	to	to	IN
cord-288231-vg8bwed9	6	41	the	the	DT
cord-288231-vg8bwed9	6	42	newly	newly	RB
cord-288231-vg8bwed9	6	43	invaded	invade	VBN
cord-288231-vg8bwed9	6	44	species	specie	NNS
cord-288231-vg8bwed9	6	45	.	.	.
cord-288231-vg8bwed9	7	1	The	the	DT
cord-288231-vg8bwed9	7	2	ultimate	ultimate	JJ
cord-288231-vg8bwed9	7	3	challenge	challenge	NN
cord-288231-vg8bwed9	7	4	is	be	VBZ
cord-288231-vg8bwed9	7	5	to	to	TO
cord-288231-vg8bwed9	7	6	link	link	VB
cord-288231-vg8bwed9	7	7	pathogen	pathogen	NN
cord-288231-vg8bwed9	7	8	and	and	CC
cord-288231-vg8bwed9	7	9	host	host	NN
cord-288231-vg8bwed9	7	10	genomics	genomic	NNS
cord-288231-vg8bwed9	7	11	data	datum	NNS
cord-288231-vg8bwed9	7	12	with	with	IN
cord-288231-vg8bwed9	7	13	biological	biological	JJ
cord-288231-vg8bwed9	7	14	outcomes	outcome	NNS
cord-288231-vg8bwed9	7	15	of	of	IN
cord-288231-vg8bwed9	7	16	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	7	17	transmission	transmission	NN
cord-288231-vg8bwed9	7	18	and	and	CC
cord-288231-vg8bwed9	7	19	to	to	TO
cord-288231-vg8bwed9	7	20	translate	translate	VB
cord-288231-vg8bwed9	7	21	the	the	DT
cord-288231-vg8bwed9	7	22	integrated	integrate	VBN
cord-288231-vg8bwed9	7	23	data	datum	NNS
cord-288231-vg8bwed9	7	24	into	into	IN
cord-288231-vg8bwed9	7	25	novel	novel	JJ
cord-288231-vg8bwed9	7	26	intervention	intervention	NN
cord-288231-vg8bwed9	7	27	strategies	strategy	NNS
cord-288231-vg8bwed9	7	28	that	that	WDT
cord-288231-vg8bwed9	7	29	eventually	eventually	RB
cord-288231-vg8bwed9	7	30	will	will	MD
cord-288231-vg8bwed9	7	31	allow	allow	VB
cord-288231-vg8bwed9	7	32	the	the	DT
cord-288231-vg8bwed9	7	33	effective	effective	JJ
cord-288231-vg8bwed9	7	34	control	control	NN
cord-288231-vg8bwed9	7	35	of	of	IN
cord-288231-vg8bwed9	7	36	newly	newly	RB
cord-288231-vg8bwed9	7	37	emerging	emerge	VBG
cord-288231-vg8bwed9	7	38	infectious	infectious	JJ
cord-288231-vg8bwed9	7	39	diseases	disease	NNS
cord-288231-vg8bwed9	7	40	.	.	.
cord-288231-vg8bwed9	8	1	result	result	VB
cord-288231-vg8bwed9	8	2	in	in	IN
cord-288231-vg8bwed9	8	3	the	the	DT
cord-288231-vg8bwed9	8	4	emergence	emergence	NN
cord-288231-vg8bwed9	8	5	of	of	IN
cord-288231-vg8bwed9	8	6	new	new	JJ
cord-288231-vg8bwed9	8	7	infectious	infectious	JJ
cord-288231-vg8bwed9	8	8	diseases	disease	NNS
cord-288231-vg8bwed9	8	9	in	in	IN
cord-288231-vg8bwed9	8	10	humans	human	NNS
cord-288231-vg8bwed9	8	11	as	as	RB
cord-288231-vg8bwed9	8	12	well	well	RB
cord-288231-vg8bwed9	8	13	as	as	IN
cord-288231-vg8bwed9	8	14	in	in	IN
cord-288231-vg8bwed9	8	15	domestic	domestic	JJ
cord-288231-vg8bwed9	8	16	and	and	CC
cord-288231-vg8bwed9	8	17	wild	wild	JJ
cord-288231-vg8bwed9	8	18	animals	animal	NNS
cord-288231-vg8bwed9	8	19	.	.	.
cord-288231-vg8bwed9	9	1	Genomics	genomic	NNS
cord-288231-vg8bwed9	9	2	tools	tool	NNS
cord-288231-vg8bwed9	9	3	such	such	JJ
cord-288231-vg8bwed9	9	4	as	as	IN
cord-288231-vg8bwed9	9	5	high	high	JJ
cord-288231-vg8bwed9	9	6	-	-	HYPH
cord-288231-vg8bwed9	9	7	throughput	throughput	NN
cord-288231-vg8bwed9	9	8	sequencing	sequencing	NN
cord-288231-vg8bwed9	9	9	,	,	,
cord-288231-vg8bwed9	9	10	mRNA	mrna	NN
cord-288231-vg8bwed9	9	11	expression	expression	NN
cord-288231-vg8bwed9	9	12	profiling	profiling	NN
cord-288231-vg8bwed9	9	13	,	,	,
cord-288231-vg8bwed9	9	14	and	and	CC
cord-288231-vg8bwed9	9	15	microarray	microarray	NN
cord-288231-vg8bwed9	9	16	-	-	HYPH
cord-288231-vg8bwed9	9	17	based	base	VBN
cord-288231-vg8bwed9	9	18	analysis	analysis	NN
cord-288231-vg8bwed9	9	19	of	of	IN
cord-288231-vg8bwed9	9	20	single	single	JJ
cord-288231-vg8bwed9	9	21	nucleotide	nucleotide	JJ
cord-288231-vg8bwed9	9	22	polymorphisms	polymorphism	NNS
cord-288231-vg8bwed9	9	23	are	be	VBP
cord-288231-vg8bwed9	9	24	providing	provide	VBG
cord-288231-vg8bwed9	9	25	unprecedented	unprecedented	JJ
cord-288231-vg8bwed9	9	26	ways	way	NNS
cord-288231-vg8bwed9	9	27	to	to	TO
cord-288231-vg8bwed9	9	28	analyze	analyze	VB
cord-288231-vg8bwed9	9	29	the	the	DT
cord-288231-vg8bwed9	9	30	diversity	diversity	NN
cord-288231-vg8bwed9	9	31	of	of	IN
cord-288231-vg8bwed9	9	32	the	the	DT
cord-288231-vg8bwed9	9	33	genomes	genome	NNS
cord-288231-vg8bwed9	9	34	of	of	IN
cord-288231-vg8bwed9	9	35	emerging	emerge	VBG
cord-288231-vg8bwed9	9	36	pathogens	pathogen	NNS
cord-288231-vg8bwed9	9	37	as	as	RB
cord-288231-vg8bwed9	9	38	well	well	RB
cord-288231-vg8bwed9	9	39	as	as	IN
cord-288231-vg8bwed9	9	40	the	the	DT
cord-288231-vg8bwed9	9	41	molecular	molecular	JJ
cord-288231-vg8bwed9	9	42	basis	basis	NN
cord-288231-vg8bwed9	9	43	of	of	IN
cord-288231-vg8bwed9	9	44	the	the	DT
cord-288231-vg8bwed9	9	45	host	host	NN
cord-288231-vg8bwed9	9	46	response	response	NN
cord-288231-vg8bwed9	9	47	to	to	IN
cord-288231-vg8bwed9	9	48	them	-PRON-	PRP
cord-288231-vg8bwed9	9	49	.	.	.
cord-288231-vg8bwed9	10	1	By	by	IN
cord-288231-vg8bwed9	10	2	comparing	compare	VBG
cord-288231-vg8bwed9	10	3	and	and	CC
cord-288231-vg8bwed9	10	4	contrasting	contrast	VBG
cord-288231-vg8bwed9	10	5	the	the	DT
cord-288231-vg8bwed9	10	6	outcomes	outcome	NNS
cord-288231-vg8bwed9	10	7	of	of	IN
cord-288231-vg8bwed9	10	8	an	an	DT
cord-288231-vg8bwed9	10	9	emerging	emerge	VBG
cord-288231-vg8bwed9	10	10	infection	infection	NN
cord-288231-vg8bwed9	10	11	with	with	IN
cord-288231-vg8bwed9	10	12	those	those	DT
cord-288231-vg8bwed9	10	13	of	of	IN
cord-288231-vg8bwed9	10	14	closely	closely	RB
cord-288231-vg8bwed9	10	15	related	related	JJ
cord-288231-vg8bwed9	10	16	pathogens	pathogen	NNS
cord-288231-vg8bwed9	10	17	in	in	IN
cord-288231-vg8bwed9	10	18	different	different	JJ
cord-288231-vg8bwed9	10	19	but	but	CC
cord-288231-vg8bwed9	10	20	related	related	JJ
cord-288231-vg8bwed9	10	21	host	host	NN
cord-288231-vg8bwed9	10	22	species	specie	NNS
cord-288231-vg8bwed9	10	23	,	,	,
cord-288231-vg8bwed9	10	24	we	-PRON-	PRP
cord-288231-vg8bwed9	10	25	can	can	MD
cord-288231-vg8bwed9	10	26	further	further	RB
cord-288231-vg8bwed9	10	27	delineate	delineate	VB
cord-288231-vg8bwed9	10	28	the	the	DT
cord-288231-vg8bwed9	10	29	various	various	JJ
cord-288231-vg8bwed9	10	30	host	host	NN
cord-288231-vg8bwed9	10	31	pathways	pathway	NNS
cord-288231-vg8bwed9	10	32	determining	determine	VBG
cord-288231-vg8bwed9	10	33	the	the	DT
cord-288231-vg8bwed9	10	34	outcome	outcome	NN
cord-288231-vg8bwed9	10	35	of	of	IN
cord-288231-vg8bwed9	10	36	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	10	37	transmission	transmission	NN
cord-288231-vg8bwed9	10	38	and	and	CC
cord-288231-vg8bwed9	10	39	adaptation	adaptation	NN
cord-288231-vg8bwed9	10	40	to	to	IN
cord-288231-vg8bwed9	10	41	the	the	DT
cord-288231-vg8bwed9	10	42	newly	newly	RB
cord-288231-vg8bwed9	10	43	invaded	invade	VBN
cord-288231-vg8bwed9	10	44	species	specie	NNS
cord-288231-vg8bwed9	10	45	.	.	.
cord-288231-vg8bwed9	11	1	The	the	DT
cord-288231-vg8bwed9	11	2	ultimate	ultimate	JJ
cord-288231-vg8bwed9	11	3	challenge	challenge	NN
cord-288231-vg8bwed9	11	4	is	be	VBZ
cord-288231-vg8bwed9	11	5	to	to	TO
cord-288231-vg8bwed9	11	6	link	link	VB
cord-288231-vg8bwed9	11	7	pathogen	pathogen	NN
cord-288231-vg8bwed9	11	8	and	and	CC
cord-288231-vg8bwed9	11	9	host	host	NN
cord-288231-vg8bwed9	11	10	genomics	genomic	NNS
cord-288231-vg8bwed9	11	11	data	datum	NNS
cord-288231-vg8bwed9	11	12	with	with	IN
cord-288231-vg8bwed9	11	13	biological	biological	JJ
cord-288231-vg8bwed9	11	14	outcomes	outcome	NNS
cord-288231-vg8bwed9	11	15	of	of	IN
cord-288231-vg8bwed9	11	16	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	11	17	transmission	transmission	NN
cord-288231-vg8bwed9	11	18	and	and	CC
cord-288231-vg8bwed9	11	19	to	to	TO
cord-288231-vg8bwed9	11	20	translate	translate	VB
cord-288231-vg8bwed9	11	21	the	the	DT
cord-288231-vg8bwed9	11	22	integrated	integrate	VBN
cord-288231-vg8bwed9	11	23	data	datum	NNS
cord-288231-vg8bwed9	11	24	into	into	IN
cord-288231-vg8bwed9	11	25	novel	novel	JJ
cord-288231-vg8bwed9	11	26	intervention	intervention	NN
cord-288231-vg8bwed9	11	27	strategies	strategy	NNS
cord-288231-vg8bwed9	11	28	that	that	WDT
cord-288231-vg8bwed9	11	29	eventually	eventually	RB
cord-288231-vg8bwed9	11	30	will	will	MD
cord-288231-vg8bwed9	11	31	allow	allow	VB
cord-288231-vg8bwed9	11	32	the	the	DT
cord-288231-vg8bwed9	11	33	effective	effective	JJ
cord-288231-vg8bwed9	11	34	control	control	NN
cord-288231-vg8bwed9	11	35	of	of	IN
cord-288231-vg8bwed9	11	36	newly	newly	RB
cord-288231-vg8bwed9	11	37	emerging	emerge	VBG
cord-288231-vg8bwed9	11	38	infectious	infectious	JJ
cord-288231-vg8bwed9	11	39	diseases	disease	NNS
cord-288231-vg8bwed9	11	40	.	.	.
cord-288231-vg8bwed9	12	1	Most	Most	JJS
cord-288231-vg8bwed9	12	2	of	of	IN
cord-288231-vg8bwed9	12	3	the	the	DT
cord-288231-vg8bwed9	12	4	well	well	RB
cord-288231-vg8bwed9	12	5	-	-	HYPH
cord-288231-vg8bwed9	12	6	known	know	VBN
cord-288231-vg8bwed9	12	7	human	human	NN
cord-288231-vg8bwed9	12	8	viruses	virus	NNS
cord-288231-vg8bwed9	12	9	persist	persist	VBP
cord-288231-vg8bwed9	12	10	in	in	IN
cord-288231-vg8bwed9	12	11	the	the	DT
cord-288231-vg8bwed9	12	12	population	population	NN
cord-288231-vg8bwed9	12	13	for	for	IN
cord-288231-vg8bwed9	12	14	a	a	DT
cord-288231-vg8bwed9	12	15	relatively	relatively	RB
cord-288231-vg8bwed9	12	16	long	long	JJ
cord-288231-vg8bwed9	12	17	time	time	NN
cord-288231-vg8bwed9	12	18	,	,	,
cord-288231-vg8bwed9	12	19	and	and	CC
cord-288231-vg8bwed9	12	20	coevolution	coevolution	NN
cord-288231-vg8bwed9	12	21	of	of	IN
cord-288231-vg8bwed9	12	22	the	the	DT
cord-288231-vg8bwed9	12	23	virus	virus	NN
cord-288231-vg8bwed9	12	24	and	and	CC
cord-288231-vg8bwed9	12	25	its	-PRON-	PRP$
cord-288231-vg8bwed9	12	26	human	human	JJ
cord-288231-vg8bwed9	12	27	host	host	NN
cord-288231-vg8bwed9	12	28	has	have	VBZ
cord-288231-vg8bwed9	12	29	resulted	result	VBN
cord-288231-vg8bwed9	12	30	in	in	IN
cord-288231-vg8bwed9	12	31	an	an	DT
cord-288231-vg8bwed9	12	32	equilibrium	equilibrium	NN
cord-288231-vg8bwed9	12	33	characterized	characterize	VBN
cord-288231-vg8bwed9	12	34	by	by	IN
cord-288231-vg8bwed9	12	35	coexistence	coexistence	NN
cord-288231-vg8bwed9	12	36	,	,	,
cord-288231-vg8bwed9	12	37	often	often	RB
cord-288231-vg8bwed9	12	38	in	in	IN
cord-288231-vg8bwed9	12	39	the	the	DT
cord-288231-vg8bwed9	12	40	absence	absence	NN
cord-288231-vg8bwed9	12	41	of	of	IN
cord-288231-vg8bwed9	12	42	a	a	DT
cord-288231-vg8bwed9	12	43	measurable	measurable	JJ
cord-288231-vg8bwed9	12	44	disease	disease	NN
cord-288231-vg8bwed9	12	45	burden	burden	NN
cord-288231-vg8bwed9	12	46	.	.	.
cord-288231-vg8bwed9	13	1	When	when	WRB
cord-288231-vg8bwed9	13	2	pathogens	pathogen	NNS
cord-288231-vg8bwed9	13	3	cross	cross	VBP
cord-288231-vg8bwed9	13	4	a	a	DT
cord-288231-vg8bwed9	13	5	species	species	NN
cord-288231-vg8bwed9	13	6	barrier	barrier	NN
cord-288231-vg8bwed9	13	7	,	,	,
cord-288231-vg8bwed9	13	8	however	however	RB
cord-288231-vg8bwed9	13	9	,	,	,
cord-288231-vg8bwed9	13	10	the	the	DT
cord-288231-vg8bwed9	13	11	infection	infection	NN
cord-288231-vg8bwed9	13	12	can	can	MD
cord-288231-vg8bwed9	13	13	be	be	VB
cord-288231-vg8bwed9	13	14	devastating	devastating	JJ
cord-288231-vg8bwed9	13	15	,	,	,
cord-288231-vg8bwed9	13	16	causing	cause	VBG
cord-288231-vg8bwed9	13	17	a	a	DT
cord-288231-vg8bwed9	13	18	high	high	JJ
cord-288231-vg8bwed9	13	19	disease	disease	NN
cord-288231-vg8bwed9	13	20	burden	burden	NN
cord-288231-vg8bwed9	13	21	and	and	CC
cord-288231-vg8bwed9	13	22	mortality	mortality	NN
cord-288231-vg8bwed9	13	23	.	.	.
cord-288231-vg8bwed9	14	1	In	in	IN
cord-288231-vg8bwed9	14	2	recent	recent	JJ
cord-288231-vg8bwed9	14	3	years	year	NNS
cord-288231-vg8bwed9	14	4	,	,	,
cord-288231-vg8bwed9	14	5	several	several	JJ
cord-288231-vg8bwed9	14	6	outbreaks	outbreak	NNS
cord-288231-vg8bwed9	14	7	of	of	IN
cord-288231-vg8bwed9	14	8	infectious	infectious	JJ
cord-288231-vg8bwed9	14	9	diseases	disease	NNS
cord-288231-vg8bwed9	14	10	in	in	IN
cord-288231-vg8bwed9	14	11	humans	human	NNS
cord-288231-vg8bwed9	14	12	linked	link	VBN
cord-288231-vg8bwed9	14	13	to	to	IN
cord-288231-vg8bwed9	14	14	such	such	PDT
cord-288231-vg8bwed9	14	15	an	an	DT
cord-288231-vg8bwed9	14	16	initial	initial	JJ
cord-288231-vg8bwed9	14	17	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	14	18	transmission	transmission	NN
cord-288231-vg8bwed9	14	19	(	(	-LRB-
cord-288231-vg8bwed9	14	20	from	from	IN
cord-288231-vg8bwed9	14	21	animal	animal	NN
cord-288231-vg8bwed9	14	22	to	to	IN
cord-288231-vg8bwed9	14	23	human	human	JJ
cord-288231-vg8bwed9	14	24	host	host	NN
cord-288231-vg8bwed9	14	25	)	)	-RRB-
cord-288231-vg8bwed9	14	26	have	have	VBP
cord-288231-vg8bwed9	14	27	highlighted	highlight	VBN
cord-288231-vg8bwed9	14	28	this	this	DT
cord-288231-vg8bwed9	14	29	problem	problem	NN
cord-288231-vg8bwed9	14	30	.	.	.
cord-288231-vg8bwed9	15	1	Factors	factor	NNS
cord-288231-vg8bwed9	15	2	related	relate	VBN
cord-288231-vg8bwed9	15	3	to	to	IN
cord-288231-vg8bwed9	15	4	our	-PRON-	PRP$
cord-288231-vg8bwed9	15	5	increasingly	increasingly	RB
cord-288231-vg8bwed9	15	6	globalized	globalize	VBN
cord-288231-vg8bwed9	15	7	society	society	NN
cord-288231-vg8bwed9	15	8	have	have	VBP
cord-288231-vg8bwed9	15	9	contributed	contribute	VBN
cord-288231-vg8bwed9	15	10	to	to	IN
cord-288231-vg8bwed9	15	11	the	the	DT
cord-288231-vg8bwed9	15	12	apparently	apparently	RB
cord-288231-vg8bwed9	15	13	increased	increase	VBN
cord-288231-vg8bwed9	15	14	transmission	transmission	NN
cord-288231-vg8bwed9	15	15	of	of	IN
cord-288231-vg8bwed9	15	16	pathogens	pathogen	NNS
cord-288231-vg8bwed9	15	17	from	from	IN
cord-288231-vg8bwed9	15	18	animals	animal	NNS
cord-288231-vg8bwed9	15	19	to	to	IN
cord-288231-vg8bwed9	15	20	humans	human	NNS
cord-288231-vg8bwed9	15	21	over	over	IN
cord-288231-vg8bwed9	15	22	the	the	DT
cord-288231-vg8bwed9	15	23	past	past	JJ
cord-288231-vg8bwed9	15	24	decades	decade	NNS
cord-288231-vg8bwed9	15	25	;	;	:
cord-288231-vg8bwed9	15	26	these	these	DT
cord-288231-vg8bwed9	15	27	include	include	VBP
cord-288231-vg8bwed9	15	28	changes	change	NNS
cord-288231-vg8bwed9	15	29	in	in	IN
cord-288231-vg8bwed9	15	30	human	human	JJ
cord-288231-vg8bwed9	15	31	factors	factor	NNS
cord-288231-vg8bwed9	15	32	such	such	JJ
cord-288231-vg8bwed9	15	33	as	as	IN
cord-288231-vg8bwed9	15	34	increased	increase	VBN
cord-288231-vg8bwed9	15	35	mobility	mobility	NN
cord-288231-vg8bwed9	15	36	,	,	,
cord-288231-vg8bwed9	15	37	demographic	demographic	JJ
cord-288231-vg8bwed9	15	38	changes	change	NNS
cord-288231-vg8bwed9	15	39	,	,	,
cord-288231-vg8bwed9	15	40	and	and	CC
cord-288231-vg8bwed9	15	41	exploitation	exploitation	NN
cord-288231-vg8bwed9	15	42	of	of	IN
cord-288231-vg8bwed9	15	43	the	the	DT
cord-288231-vg8bwed9	15	44	environment	environment	NN
cord-288231-vg8bwed9	15	45	(	(	-LRB-
cord-288231-vg8bwed9	15	46	for	for	IN
cord-288231-vg8bwed9	15	47	a	a	DT
cord-288231-vg8bwed9	15	48	review	review	NN
cord-288231-vg8bwed9	15	49	see	see	VB
cord-288231-vg8bwed9	15	50	Osterhaus	Osterhaus	NNP
cord-288231-vg8bwed9	15	51	[	[	-LRB-
cord-288231-vg8bwed9	15	52	1	1	CD
cord-288231-vg8bwed9	15	53	]	]	-RRB-
cord-288231-vg8bwed9	15	54	and	and	CC
cord-288231-vg8bwed9	15	55	Kuiken	Kuiken	NNP
cord-288231-vg8bwed9	15	56	et	et	FW
cord-288231-vg8bwed9	15	57	al	al	NNP
cord-288231-vg8bwed9	15	58	.	.	.
cord-288231-vg8bwed9	16	1	[	[	-LRB-
cord-288231-vg8bwed9	16	2	2	2	CD
cord-288231-vg8bwed9	16	3	]	]	-RRB-
cord-288231-vg8bwed9	16	4	)	)	-RRB-
cord-288231-vg8bwed9	16	5	.	.	.
cord-288231-vg8bwed9	17	1	Environmental	environmental	JJ
cord-288231-vg8bwed9	17	2	factors	factor	NNS
cord-288231-vg8bwed9	17	3	also	also	RB
cord-288231-vg8bwed9	17	4	play	play	VBP
cord-288231-vg8bwed9	17	5	a	a	DT
cord-288231-vg8bwed9	17	6	direct	direct	JJ
cord-288231-vg8bwed9	17	7	role	role	NN
cord-288231-vg8bwed9	17	8	,	,	,
cord-288231-vg8bwed9	17	9	and	and	CC
cord-288231-vg8bwed9	17	10	many	many	JJ
cord-288231-vg8bwed9	17	11	examples	example	NNS
cord-288231-vg8bwed9	17	12	exist	exist	VBP
cord-288231-vg8bwed9	17	13	.	.	.
cord-288231-vg8bwed9	18	1	The	the	DT
cord-288231-vg8bwed9	18	2	recently	recently	RB
cord-288231-vg8bwed9	18	3	increased	increase	VBN
cord-288231-vg8bwed9	18	4	distribution	distribution	NN
cord-288231-vg8bwed9	18	5	of	of	IN
cord-288231-vg8bwed9	18	6	the	the	DT
cord-288231-vg8bwed9	18	7	arthropod	arthropod	NNP
cord-288231-vg8bwed9	18	8	(	(	-LRB-
cord-288231-vg8bwed9	18	9	mosquito	mosquito	NN
cord-288231-vg8bwed9	18	10	)	)	-RRB-
cord-288231-vg8bwed9	18	11	vector	vector	NN
cord-288231-vg8bwed9	18	12	Aedes	Aedes	NNP
cord-288231-vg8bwed9	18	13	aegypti	aegypti	NN
cord-288231-vg8bwed9	18	14	,	,	,
cord-288231-vg8bwed9	18	15	for	for	IN
cord-288231-vg8bwed9	18	16	example	example	NN
cord-288231-vg8bwed9	18	17	,	,	,
cord-288231-vg8bwed9	18	18	has	have	VBZ
cord-288231-vg8bwed9	18	19	led	lead	VBN
cord-288231-vg8bwed9	18	20	to	to	IN
cord-288231-vg8bwed9	18	21	massive	massive	JJ
cord-288231-vg8bwed9	18	22	outbreaks	outbreak	NNS
cord-288231-vg8bwed9	18	23	of	of	IN
cord-288231-vg8bwed9	18	24	dengue	dengue	NN
cord-288231-vg8bwed9	18	25	fever	fever	NN
cord-288231-vg8bwed9	18	26	in	in	IN
cord-288231-vg8bwed9	18	27	South	South	NNP
cord-288231-vg8bwed9	18	28	America	America	NNP
cord-288231-vg8bwed9	18	29	and	and	CC
cord-288231-vg8bwed9	18	30	Southeast	Southeast	NNP
cord-288231-vg8bwed9	18	31	Asia	Asia	NNP
cord-288231-vg8bwed9	18	32	.	.	.
cord-288231-vg8bwed9	19	1	Intense	intense	JJ
cord-288231-vg8bwed9	19	2	pig	pig	NN
cord-288231-vg8bwed9	19	3	farming	farming	NN
cord-288231-vg8bwed9	19	4	in	in	IN
cord-288231-vg8bwed9	19	5	areas	area	NNS
cord-288231-vg8bwed9	19	6	where	where	WRB
cord-288231-vg8bwed9	19	7	frugivorous	frugivorous	JJ
cord-288231-vg8bwed9	19	8	bats	bat	NNS
cord-288231-vg8bwed9	19	9	are	be	VBP
cord-288231-vg8bwed9	19	10	common	common	JJ
cord-288231-vg8bwed9	19	11	is	be	VBZ
cord-288231-vg8bwed9	19	12	probably	probably	RB
cord-288231-vg8bwed9	19	13	the	the	DT
cord-288231-vg8bwed9	19	14	direct	direct	JJ
cord-288231-vg8bwed9	19	15	cause	cause	NN
cord-288231-vg8bwed9	19	16	of	of	IN
cord-288231-vg8bwed9	19	17	the	the	DT
cord-288231-vg8bwed9	19	18	introduction	introduction	NN
cord-288231-vg8bwed9	19	19	of	of	IN
cord-288231-vg8bwed9	19	20	Nipah	Nipah	NNP
cord-288231-vg8bwed9	19	21	virus	virus	NN
cord-288231-vg8bwed9	19	22	into	into	IN
cord-288231-vg8bwed9	19	23	pig	pig	NN
cord-288231-vg8bwed9	19	24	populations	population	NNS
cord-288231-vg8bwed9	19	25	in	in	IN
cord-288231-vg8bwed9	19	26	Malaysia	Malaysia	NNP
cord-288231-vg8bwed9	19	27	,	,	,
cord-288231-vg8bwed9	19	28	with	with	IN
cord-288231-vg8bwed9	19	29	subsequent	subsequent	JJ
cord-288231-vg8bwed9	19	30	transmission	transmission	NN
cord-288231-vg8bwed9	19	31	to	to	IN
cord-288231-vg8bwed9	19	32	humans	human	NNS
cord-288231-vg8bwed9	19	33	.	.	.
cord-288231-vg8bwed9	20	1	Bats	bat	NNS
cord-288231-vg8bwed9	20	2	are	be	VBP
cord-288231-vg8bwed9	20	3	an	an	DT
cord-288231-vg8bwed9	20	4	important	important	JJ
cord-288231-vg8bwed9	20	5	reservoir	reservoir	NN
cord-288231-vg8bwed9	20	6	for	for	IN
cord-288231-vg8bwed9	20	7	a	a	DT
cord-288231-vg8bwed9	20	8	plethora	plethora	NN
cord-288231-vg8bwed9	20	9	of	of	IN
cord-288231-vg8bwed9	20	10	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	20	11	pathogens	pathogen	NNS
cord-288231-vg8bwed9	20	12	:	:	:
cord-288231-vg8bwed9	20	13	two	two	CD
cord-288231-vg8bwed9	20	14	closely	closely	RB
cord-288231-vg8bwed9	20	15	related	relate	VBN
cord-288231-vg8bwed9	20	16	paramyxoviruses	paramyxovirus	NNS
cord-288231-vg8bwed9	20	17	-	-	HYPH
cord-288231-vg8bwed9	20	18	Hendra	Hendra	NNP
cord-288231-vg8bwed9	20	19	virus	virus	NN
cord-288231-vg8bwed9	20	20	and	and	CC
cord-288231-vg8bwed9	20	21	Nipah	Nipah	NNP
cord-288231-vg8bwed9	20	22	virus	virus	NN
cord-288231-vg8bwed9	20	23	-	-	HYPH
cord-288231-vg8bwed9	20	24	cause	cause	VBP
cord-288231-vg8bwed9	20	25	persistent	persistent	JJ
cord-288231-vg8bwed9	20	26	infections	infection	NNS
cord-288231-vg8bwed9	20	27	in	in	IN
cord-288231-vg8bwed9	20	28	frugivorous	frugivorous	JJ
cord-288231-vg8bwed9	20	29	bats	bat	NNS
cord-288231-vg8bwed9	20	30	and	and	CC
cord-288231-vg8bwed9	20	31	have	have	VBP
cord-288231-vg8bwed9	20	32	spread	spread	VBN
cord-288231-vg8bwed9	20	33	to	to	IN
cord-288231-vg8bwed9	20	34	horses	horse	NNS
cord-288231-vg8bwed9	20	35	and	and	CC
cord-288231-vg8bwed9	20	36	pigs	pig	NNS
cord-288231-vg8bwed9	20	37	,	,	,
cord-288231-vg8bwed9	20	38	respectively	respectively	RB
cord-288231-vg8bwed9	20	39	[	[	-LRB-
cord-288231-vg8bwed9	20	40	3	3	CD
cord-288231-vg8bwed9	20	41	]	]	-RRB-
cord-288231-vg8bwed9	20	42	.	.	.
cord-288231-vg8bwed9	21	1	The	the	DT
cord-288231-vg8bwed9	21	2	similarity	similarity	NN
cord-288231-vg8bwed9	21	3	between	between	IN
cord-288231-vg8bwed9	21	4	human	human	JJ
cord-288231-vg8bwed9	21	5	and	and	CC
cord-288231-vg8bwed9	21	6	nonhuman	nonhuman	NN
cord-288231-vg8bwed9	21	7	primates	primate	NNS
cord-288231-vg8bwed9	21	8	permits	permit	VBZ
cord-288231-vg8bwed9	21	9	many	many	JJ
cord-288231-vg8bwed9	21	10	viruses	virus	NNS
cord-288231-vg8bwed9	21	11	to	to	TO
cord-288231-vg8bwed9	21	12	cross	cross	VB
cord-288231-vg8bwed9	21	13	the	the	DT
cord-288231-vg8bwed9	21	14	species	specie	NNS
cord-288231-vg8bwed9	21	15	barrier	barrier	NN
cord-288231-vg8bwed9	21	16	between	between	IN
cord-288231-vg8bwed9	21	17	different	different	JJ
cord-288231-vg8bwed9	21	18	primate	primate	JJ
cord-288231-vg8bwed9	21	19	species	specie	NNS
cord-288231-vg8bwed9	21	20	.	.	.
cord-288231-vg8bwed9	22	1	The	the	DT
cord-288231-vg8bwed9	22	2	introduction	introduction	NN
cord-288231-vg8bwed9	22	3	into	into	IN
cord-288231-vg8bwed9	22	4	humans	human	NNS
cord-288231-vg8bwed9	22	5	of	of	IN
cord-288231-vg8bwed9	22	6	HIV-1	HIV-1	NNP
cord-288231-vg8bwed9	23	1	and	and	CC
cord-288231-vg8bwed9	23	2	HIV-2	HIV-2	NNP
cord-288231-vg8bwed9	23	3	(	(	-LRB-
cord-288231-vg8bwed9	23	4	the	the	DT
cord-288231-vg8bwed9	23	5	lentiviruses	lentiviruse	NNS
cord-288231-vg8bwed9	23	6	that	that	WDT
cord-288231-vg8bwed9	23	7	cause	cause	VBP
cord-288231-vg8bwed9	23	8	AIDS	AIDS	NNP
cord-288231-vg8bwed9	23	9	)	)	-RRB-
cord-288231-vg8bwed9	23	10	,	,	,
cord-288231-vg8bwed9	23	11	as	as	RB
cord-288231-vg8bwed9	23	12	well	well	RB
cord-288231-vg8bwed9	23	13	as	as	IN
cord-288231-vg8bwed9	23	14	other	other	JJ
cord-288231-vg8bwed9	23	15	primate	primate	NN
cord-288231-vg8bwed9	23	16	viruses	virus	NNS
cord-288231-vg8bwed9	23	17	,	,	,
cord-288231-vg8bwed9	23	18	such	such	JJ
cord-288231-vg8bwed9	23	19	as	as	IN
cord-288231-vg8bwed9	23	20	monkeypox	monkeypox	NN
cord-288231-vg8bwed9	23	21	virus	virus	NN
cord-288231-vg8bwed9	23	22	and	and	CC
cord-288231-vg8bwed9	23	23	Herpesvirus	Herpesvirus	NNP
cord-288231-vg8bwed9	23	24	simiae	simiae	NN
cord-288231-vg8bwed9	23	25	,	,	,
cord-288231-vg8bwed9	23	26	provide	provide	VB
cord-288231-vg8bwed9	23	27	dramatic	dramatic	JJ
cord-288231-vg8bwed9	23	28	examples	example	NNS
cord-288231-vg8bwed9	23	29	of	of	IN
cord-288231-vg8bwed9	23	30	this	this	DT
cord-288231-vg8bwed9	23	31	type	type	NN
cord-288231-vg8bwed9	23	32	of	of	IN
cord-288231-vg8bwed9	23	33	transmission	transmission	NN
cord-288231-vg8bwed9	23	34	.	.	.
cord-288231-vg8bwed9	24	1	Other	other	JJ
cord-288231-vg8bwed9	24	2	viruses	virus	NNS
cord-288231-vg8bwed9	24	3	,	,	,
cord-288231-vg8bwed9	24	4	such	such	JJ
cord-288231-vg8bwed9	24	5	as	as	IN
cord-288231-vg8bwed9	24	6	influenza	influenza	NN
cord-288231-vg8bwed9	24	7	A	a	DT
cord-288231-vg8bwed9	24	8	viruses	virus	NNS
cord-288231-vg8bwed9	24	9	and	and	CC
cord-288231-vg8bwed9	24	10	severe	severe	JJ
cord-288231-vg8bwed9	24	11	acute	acute	JJ
cord-288231-vg8bwed9	24	12	respiratory	respiratory	JJ
cord-288231-vg8bwed9	24	13	syndrome	syndrome	NN
cord-288231-vg8bwed9	24	14	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	24	15	(	(	-LRB-
cord-288231-vg8bwed9	24	16	SARS	SARS	NNP
cord-288231-vg8bwed9	24	17	-	-	HYPH
cord-288231-vg8bwed9	24	18	CoV	CoV	NNP
cord-288231-vg8bwed9	24	19	)	)	-RRB-
cord-288231-vg8bwed9	24	20	,	,	,
cord-288231-vg8bwed9	24	21	may	may	MD
cord-288231-vg8bwed9	24	22	need	need	VB
cord-288231-vg8bwed9	24	23	multiple	multiple	JJ
cord-288231-vg8bwed9	24	24	genetic	genetic	JJ
cord-288231-vg8bwed9	24	25	changes	change	NNS
cord-288231-vg8bwed9	24	26	to	to	TO
cord-288231-vg8bwed9	24	27	adapt	adapt	VB
cord-288231-vg8bwed9	24	28	successfully	successfully	RB
cord-288231-vg8bwed9	24	29	to	to	IN
cord-288231-vg8bwed9	24	30	humans	human	NNS
cord-288231-vg8bwed9	24	31	as	as	IN
cord-288231-vg8bwed9	24	32	a	a	DT
cord-288231-vg8bwed9	24	33	new	new	JJ
cord-288231-vg8bwed9	24	34	host	host	NN
cord-288231-vg8bwed9	24	35	species	species	NN
cord-288231-vg8bwed9	24	36	;	;	:
cord-288231-vg8bwed9	24	37	these	these	DT
cord-288231-vg8bwed9	24	38	changes	change	NNS
cord-288231-vg8bwed9	24	39	might	may	MD
cord-288231-vg8bwed9	24	40	include	include	VB
cord-288231-vg8bwed9	24	41	differential	differential	JJ
cord-288231-vg8bwed9	24	42	receptor	receptor	NN
cord-288231-vg8bwed9	24	43	usage	usage	NN
cord-288231-vg8bwed9	24	44	,	,	,
cord-288231-vg8bwed9	24	45	enhanced	enhanced	JJ
cord-288231-vg8bwed9	24	46	replication	replication	NN
cord-288231-vg8bwed9	24	47	,	,	,
cord-288231-vg8bwed9	24	48	evasion	evasion	NN
cord-288231-vg8bwed9	24	49	of	of	IN
cord-288231-vg8bwed9	24	50	innate	innate	JJ
cord-288231-vg8bwed9	24	51	and	and	CC
cord-288231-vg8bwed9	24	52	adaptive	adaptive	JJ
cord-288231-vg8bwed9	24	53	host	host	NN
cord-288231-vg8bwed9	24	54	immune	immune	JJ
cord-288231-vg8bwed9	24	55	defenses	defense	NNS
cord-288231-vg8bwed9	24	56	,	,	,
cord-288231-vg8bwed9	24	57	and/or	and/or	CC
cord-288231-vg8bwed9	24	58	increased	increase	VBN
cord-288231-vg8bwed9	24	59	efficiency	efficiency	NN
cord-288231-vg8bwed9	24	60	of	of	IN
cord-288231-vg8bwed9	24	61	transmission	transmission	NN
cord-288231-vg8bwed9	24	62	.	.	.
cord-288231-vg8bwed9	25	1	Understanding	understand	VBG
cord-288231-vg8bwed9	25	2	the	the	DT
cord-288231-vg8bwed9	25	3	complex	complex	JJ
cord-288231-vg8bwed9	25	4	interactions	interaction	NNS
cord-288231-vg8bwed9	25	5	between	between	IN
cord-288231-vg8bwed9	25	6	the	the	DT
cord-288231-vg8bwed9	25	7	invading	invade	VBG
cord-288231-vg8bwed9	25	8	pathogen	pathogen	NN
cord-288231-vg8bwed9	25	9	on	on	IN
cord-288231-vg8bwed9	25	10	the	the	DT
cord-288231-vg8bwed9	25	11	one	one	CD
cord-288231-vg8bwed9	25	12	hand	hand	NN
cord-288231-vg8bwed9	25	13	and	and	CC
cord-288231-vg8bwed9	25	14	the	the	DT
cord-288231-vg8bwed9	25	15	new	new	JJ
cord-288231-vg8bwed9	25	16	host	host	NN
cord-288231-vg8bwed9	25	17	on	on	IN
cord-288231-vg8bwed9	25	18	the	the	DT
cord-288231-vg8bwed9	25	19	other	other	JJ
cord-288231-vg8bwed9	25	20	as	as	IN
cord-288231-vg8bwed9	25	21	they	-PRON-	PRP
cord-288231-vg8bwed9	25	22	progress	progress	VBP
cord-288231-vg8bwed9	25	23	toward	toward	IN
cord-288231-vg8bwed9	25	24	a	a	DT
cord-288231-vg8bwed9	25	25	new	new	JJ
cord-288231-vg8bwed9	25	26	hostpathogen	hostpathogen	NN
cord-288231-vg8bwed9	25	27	equilibrium	equilibrium	NN
cord-288231-vg8bwed9	25	28	is	be	VBZ
cord-288231-vg8bwed9	25	29	a	a	DT
cord-288231-vg8bwed9	25	30	major	major	JJ
cord-288231-vg8bwed9	25	31	challenge	challenge	NN
cord-288231-vg8bwed9	25	32	that	that	WDT
cord-288231-vg8bwed9	25	33	differs	differ	VBZ
cord-288231-vg8bwed9	25	34	substantially	substantially	RB
cord-288231-vg8bwed9	25	35	for	for	IN
cord-288231-vg8bwed9	25	36	each	each	DT
cord-288231-vg8bwed9	25	37	successful	successful	JJ
cord-288231-vg8bwed9	25	38	interspecies	interspecie	NNS
cord-288231-vg8bwed9	25	39	transmission	transmission	NN
cord-288231-vg8bwed9	25	40	and	and	CC
cord-288231-vg8bwed9	25	41	subsequent	subsequent	JJ
cord-288231-vg8bwed9	25	42	spread	spread	NN
cord-288231-vg8bwed9	25	43	of	of	IN
cord-288231-vg8bwed9	25	44	the	the	DT
cord-288231-vg8bwed9	25	45	virus	virus	NN
cord-288231-vg8bwed9	25	46	.	.	.
cord-288231-vg8bwed9	26	1	New	new	JJ
cord-288231-vg8bwed9	26	2	molecular	molecular	JJ
cord-288231-vg8bwed9	26	3	techniques	technique	NNS
cord-288231-vg8bwed9	26	4	such	such	JJ
cord-288231-vg8bwed9	26	5	as	as	IN
cord-288231-vg8bwed9	26	6	high	high	JJ
cord-288231-vg8bwed9	26	7	-	-	HYPH
cord-288231-vg8bwed9	26	8	throughput	throughput	NN
cord-288231-vg8bwed9	26	9	sequencing	sequencing	NN
cord-288231-vg8bwed9	26	10	,	,	,
cord-288231-vg8bwed9	26	11	mRNA	mrna	NN
cord-288231-vg8bwed9	26	12	expression	expression	NN
cord-288231-vg8bwed9	26	13	profiling	profiling	NN
cord-288231-vg8bwed9	26	14	,	,	,
cord-288231-vg8bwed9	26	15	and	and	CC
cord-288231-vg8bwed9	26	16	array	array	NN
cord-288231-vg8bwed9	26	17	-	-	HYPH
cord-288231-vg8bwed9	26	18	based	base	VBN
cord-288231-vg8bwed9	26	19	single	single	JJ
cord-288231-vg8bwed9	26	20	nucleotide	nucleotide	JJ
cord-288231-vg8bwed9	26	21	polymorphism	polymorphism	NN
cord-288231-vg8bwed9	26	22	(	(	-LRB-
cord-288231-vg8bwed9	26	23	SNP	SNP	NNP
cord-288231-vg8bwed9	26	24	)	)	-RRB-
cord-288231-vg8bwed9	26	25	analysis	analysis	NN
cord-288231-vg8bwed9	26	26	provide	provide	VBP
cord-288231-vg8bwed9	26	27	ways	way	NNS
cord-288231-vg8bwed9	26	28	to	to	TO
cord-288231-vg8bwed9	26	29	rapidly	rapidly	RB
cord-288231-vg8bwed9	26	30	identify	identify	VB
cord-288231-vg8bwed9	26	31	emerging	emerge	VBG
cord-288231-vg8bwed9	26	32	pathogens	pathogen	NNS
cord-288231-vg8bwed9	26	33	(	(	-LRB-
cord-288231-vg8bwed9	26	34	Nipah	Nipah	NNP
cord-288231-vg8bwed9	26	35	virus	virus	NN
cord-288231-vg8bwed9	26	36	and	and	CC
cord-288231-vg8bwed9	26	37	SARS	SARS	NNP
cord-288231-vg8bwed9	26	38	-	-	HYPH
cord-288231-vg8bwed9	26	39	CoV	CoV	NNP
cord-288231-vg8bwed9	26	40	,	,	,
cord-288231-vg8bwed9	26	41	for	for	IN
cord-288231-vg8bwed9	26	42	example	example	NN
cord-288231-vg8bwed9	26	43	)	)	-RRB-
cord-288231-vg8bwed9	26	44	and	and	CC
cord-288231-vg8bwed9	26	45	to	to	TO
cord-288231-vg8bwed9	26	46	analyze	analyze	VB
cord-288231-vg8bwed9	26	47	the	the	DT
cord-288231-vg8bwed9	26	48	diversity	diversity	NN
cord-288231-vg8bwed9	26	49	of	of	IN
cord-288231-vg8bwed9	26	50	their	-PRON-	PRP$
cord-288231-vg8bwed9	26	51	genomes	genome	NNS
cord-288231-vg8bwed9	26	52	as	as	RB
cord-288231-vg8bwed9	26	53	well	well	RB
cord-288231-vg8bwed9	26	54	as	as	IN
cord-288231-vg8bwed9	26	55	the	the	DT
cord-288231-vg8bwed9	26	56	host	host	NN
cord-288231-vg8bwed9	26	57	responses	response	NNS
cord-288231-vg8bwed9	26	58	against	against	IN
cord-288231-vg8bwed9	26	59	them	-PRON-	PRP
cord-288231-vg8bwed9	26	60	.	.	.
cord-288231-vg8bwed9	27	1	Essential	essential	JJ
cord-288231-vg8bwed9	27	2	to	to	IN
cord-288231-vg8bwed9	27	3	the	the	DT
cord-288231-vg8bwed9	27	4	process	process	NN
cord-288231-vg8bwed9	27	5	of	of	IN
cord-288231-vg8bwed9	27	6	identification	identification	NN
cord-288231-vg8bwed9	27	7	and	and	CC
cord-288231-vg8bwed9	27	8	characterization	characterization	NN
cord-288231-vg8bwed9	27	9	of	of	IN
cord-288231-vg8bwed9	27	10	genome	genome	NN
cord-288231-vg8bwed9	27	11	sequences	sequence	NNS
cord-288231-vg8bwed9	27	12	is	be	VBZ
cord-288231-vg8bwed9	27	13	the	the	DT
cord-288231-vg8bwed9	27	14	exploitation	exploitation	NN
cord-288231-vg8bwed9	27	15	of	of	IN
cord-288231-vg8bwed9	27	16	extensive	extensive	JJ
cord-288231-vg8bwed9	27	17	databases	database	NNS
cord-288231-vg8bwed9	27	18	that	that	WDT
cord-288231-vg8bwed9	27	19	allow	allow	VBP
cord-288231-vg8bwed9	27	20	the	the	DT
cord-288231-vg8bwed9	27	21	alignment	alignment	NN
cord-288231-vg8bwed9	27	22	of	of	IN
cord-288231-vg8bwed9	27	23	viral	viral	JJ
cord-288231-vg8bwed9	27	24	genome	genome	NN
cord-288231-vg8bwed9	27	25	sequences	sequence	NNS
cord-288231-vg8bwed9	27	26	and	and	CC
cord-288231-vg8bwed9	27	27	the	the	DT
cord-288231-vg8bwed9	27	28	linkage	linkage	NN
cord-288231-vg8bwed9	27	29	of	of	IN
cord-288231-vg8bwed9	27	30	these	these	DT
cord-288231-vg8bwed9	27	31	genomics	genomic	NNS
cord-288231-vg8bwed9	27	32	data	datum	NNS
cord-288231-vg8bwed9	27	33	to	to	IN
cord-288231-vg8bwed9	27	34	those	those	DT
cord-288231-vg8bwed9	27	35	obtained	obtain	VBN
cord-288231-vg8bwed9	27	36	by	by	IN
cord-288231-vg8bwed9	27	37	classical	classical	JJ
cord-288231-vg8bwed9	27	38	viral	viral	JJ
cord-288231-vg8bwed9	27	39	culture	culture	NN
cord-288231-vg8bwed9	27	40	and	and	CC
cord-288231-vg8bwed9	27	41	serological	serological	JJ
cord-288231-vg8bwed9	27	42	techniques	technique	NNS
cord-288231-vg8bwed9	27	43	,	,	,
cord-288231-vg8bwed9	27	44	and	and	CC
cord-288231-vg8bwed9	27	45	epidemiological	epidemiological	JJ
cord-288231-vg8bwed9	27	46	,	,	,
cord-288231-vg8bwed9	27	47	clinical	clinical	JJ
cord-288231-vg8bwed9	27	48	,	,	,
cord-288231-vg8bwed9	27	49	and	and	CC
cord-288231-vg8bwed9	27	50	pathological	pathological	JJ
cord-288231-vg8bwed9	27	51	studies	study	NNS
cord-288231-vg8bwed9	27	52	[	[	-LRB-
cord-288231-vg8bwed9	27	53	4	4	CD
cord-288231-vg8bwed9	27	54	]	]	-RRB-
cord-288231-vg8bwed9	27	55	.	.	.
cord-288231-vg8bwed9	28	1	Extensive	extensive	JJ
cord-288231-vg8bwed9	28	2	genetic	genetic	JJ
cord-288231-vg8bwed9	28	3	analysis	analysis	NN
cord-288231-vg8bwed9	28	4	of	of	IN
cord-288231-vg8bwed9	28	5	HIV-1	HIV-1	NNP
cord-288231-vg8bwed9	28	6	,	,	,
cord-288231-vg8bwed9	28	7	for	for	IN
cord-288231-vg8bwed9	28	8	example	example	NN
cord-288231-vg8bwed9	28	9	,	,	,
cord-288231-vg8bwed9	28	10	has	have	VBZ
cord-288231-vg8bwed9	28	11	provided	provide	VBN
cord-288231-vg8bwed9	28	12	clues	clue	NNS
cord-288231-vg8bwed9	28	13	to	to	IN
cord-288231-vg8bwed9	28	14	the	the	DT
cord-288231-vg8bwed9	28	15	geography	geography	NN
cord-288231-vg8bwed9	28	16	and	and	CC
cord-288231-vg8bwed9	28	17	time	time	NN
cord-288231-vg8bwed9	28	18	scale	scale	NN
cord-288231-vg8bwed9	28	19	of	of	IN
cord-288231-vg8bwed9	28	20	the	the	DT
cord-288231-vg8bwed9	28	21	early	early	JJ
cord-288231-vg8bwed9	28	22	diversification	diversification	NN
cord-288231-vg8bwed9	28	23	of	of	IN
cord-288231-vg8bwed9	28	24	HIV-1	HIV-1	NNP
cord-288231-vg8bwed9	28	25	strains	strain	NNS
cord-288231-vg8bwed9	28	26	when	when	WRB
cord-288231-vg8bwed9	28	27	the	the	DT
cord-288231-vg8bwed9	28	28	virus	virus	NN
cord-288231-vg8bwed9	28	29	emerged	emerge	VBD
cord-288231-vg8bwed9	28	30	in	in	IN
cord-288231-vg8bwed9	28	31	humans	human	NNS
cord-288231-vg8bwed9	28	32	.	.	.
cord-288231-vg8bwed9	29	1	HIV-1	HIV-1	NNP
cord-288231-vg8bwed9	29	2	strains	strain	NNS
cord-288231-vg8bwed9	29	3	are	be	VBP
cord-288231-vg8bwed9	29	4	divided	divide	VBN
cord-288231-vg8bwed9	29	5	into	into	IN
cord-288231-vg8bwed9	29	6	multiple	multiple	JJ
cord-288231-vg8bwed9	29	7	clades	clade	NNS
cord-288231-vg8bwed9	29	8	,	,	,
cord-288231-vg8bwed9	29	9	each	each	DT
cord-288231-vg8bwed9	29	10	of	of	IN
cord-288231-vg8bwed9	29	11	which	which	WDT
cord-288231-vg8bwed9	29	12	has	have	VBZ
cord-288231-vg8bwed9	29	13	independently	independently	RB
cord-288231-vg8bwed9	29	14	evolved	evolve	VBN
cord-288231-vg8bwed9	29	15	from	from	IN
cord-288231-vg8bwed9	29	16	a	a	DT
cord-288231-vg8bwed9	29	17	simian	simian	JJ
cord-288231-vg8bwed9	29	18	immunodeficiency	immunodeficiency	NN
cord-288231-vg8bwed9	29	19	virus	virus	NN
cord-288231-vg8bwed9	29	20	(	(	-LRB-
cord-288231-vg8bwed9	29	21	SIV	SIV	NNP
cord-288231-vg8bwed9	29	22	)	)	-RRB-
cord-288231-vg8bwed9	29	23	that	that	WDT
cord-288231-vg8bwed9	29	24	naturally	naturally	RB
cord-288231-vg8bwed9	29	25	infects	infect	VBZ
cord-288231-vg8bwed9	29	26	chimpanzees	chimpanzee	NNS
cord-288231-vg8bwed9	29	27	in	in	IN
cord-288231-vg8bwed9	29	28	West	West	NNP
cord-288231-vg8bwed9	29	29	and	and	CC
cord-288231-vg8bwed9	29	30	Central	Central	NNP
cord-288231-vg8bwed9	29	31	Africa	Africa	NNP
cord-288231-vg8bwed9	29	32	.	.	.
cord-288231-vg8bwed9	30	1	Current	current	JJ
cord-288231-vg8bwed9	30	2	estimates	estimate	NNS
cord-288231-vg8bwed9	30	3	date	date	VBP
cord-288231-vg8bwed9	30	4	the	the	DT
cord-288231-vg8bwed9	30	5	common	common	JJ
cord-288231-vg8bwed9	30	6	ancestor	ancestor	NN
cord-288231-vg8bwed9	30	7	of	of	IN
cord-288231-vg8bwed9	30	8	HIV-1	HIV-1	NNP
cord-288231-vg8bwed9	30	9	to	to	IN
cord-288231-vg8bwed9	30	10	the	the	DT
cord-288231-vg8bwed9	30	11	beginning	beginning	NN
cord-288231-vg8bwed9	30	12	of	of	IN
cord-288231-vg8bwed9	30	13	the	the	DT
cord-288231-vg8bwed9	30	14	twentieth	twentieth	JJ
cord-288231-vg8bwed9	30	15	century	century	NN
cord-288231-vg8bwed9	30	16	[	[	-LRB-
cord-288231-vg8bwed9	30	17	5	5	CD
cord-288231-vg8bwed9	30	18	]	]	-RRB-
cord-288231-vg8bwed9	30	19	.	.	.
cord-288231-vg8bwed9	31	1	Because	because	IN
cord-288231-vg8bwed9	31	2	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	31	3	pathogens	pathogen	NNS
cord-288231-vg8bwed9	31	4	typically	typically	RB
cord-288231-vg8bwed9	31	5	may	may	MD
cord-288231-vg8bwed9	31	6	cause	cause	VB
cord-288231-vg8bwed9	31	7	variable	variable	JJ
cord-288231-vg8bwed9	31	8	clinical	clinical	JJ
cord-288231-vg8bwed9	31	9	outcomes	outcome	NNS
cord-288231-vg8bwed9	31	10	in	in	IN
cord-288231-vg8bwed9	31	11	human	human	JJ
cord-288231-vg8bwed9	31	12	hosts	host	NNS
cord-288231-vg8bwed9	31	13	that	that	WDT
cord-288231-vg8bwed9	31	14	differ	differ	VBP
cord-288231-vg8bwed9	31	15	in	in	IN
cord-288231-vg8bwed9	31	16	age	age	NN
cord-288231-vg8bwed9	31	17	,	,	,
cord-288231-vg8bwed9	31	18	nutritional	nutritional	JJ
cord-288231-vg8bwed9	31	19	status	status	NN
cord-288231-vg8bwed9	31	20	,	,	,
cord-288231-vg8bwed9	31	21	genetic	genetic	JJ
cord-288231-vg8bwed9	31	22	background	background	NN
cord-288231-vg8bwed9	31	23	,	,	,
cord-288231-vg8bwed9	31	24	and	and	CC
cord-288231-vg8bwed9	31	25	immunological	immunological	JJ
cord-288231-vg8bwed9	31	26	condition	condition	NN
cord-288231-vg8bwed9	31	27	,	,	,
cord-288231-vg8bwed9	31	28	deciphering	decipher	VBG
cord-288231-vg8bwed9	31	29	the	the	DT
cord-288231-vg8bwed9	31	30	complex	complex	JJ
cord-288231-vg8bwed9	31	31	interactions	interaction	NNS
cord-288231-vg8bwed9	31	32	between	between	IN
cord-288231-vg8bwed9	31	33	evolving	evolve	VBG
cord-288231-vg8bwed9	31	34	pathogens	pathogen	NNS
cord-288231-vg8bwed9	31	35	and	and	CC
cord-288231-vg8bwed9	31	36	their	-PRON-	PRP$
cord-288231-vg8bwed9	31	37	hosts	host	NNS
cord-288231-vg8bwed9	31	38	is	be	VBZ
cord-288231-vg8bwed9	31	39	a	a	DT
cord-288231-vg8bwed9	31	40	great	great	JJ
cord-288231-vg8bwed9	31	41	challenge	challenge	NN
cord-288231-vg8bwed9	31	42	.	.	.
cord-288231-vg8bwed9	32	1	The	the	DT
cord-288231-vg8bwed9	32	2	genome	genome	NN
cord-288231-vg8bwed9	32	3	sequences	sequence	NNS
cord-288231-vg8bwed9	32	4	of	of	IN
cord-288231-vg8bwed9	32	5	many	many	JJ
cord-288231-vg8bwed9	32	6	host	host	NN
cord-288231-vg8bwed9	32	7	species	specie	NNS
cord-288231-vg8bwed9	32	8	have	have	VBP
cord-288231-vg8bwed9	32	9	become	become	VBN
cord-288231-vg8bwed9	32	10	available	available	JJ
cord-288231-vg8bwed9	32	11	the	the	DT
cord-288231-vg8bwed9	32	12	last	last	JJ
cord-288231-vg8bwed9	32	13	decade	decade	NN
cord-288231-vg8bwed9	32	14	,	,	,
cord-288231-vg8bwed9	32	15	and	and	CC
cord-288231-vg8bwed9	32	16	with	with	IN
cord-288231-vg8bwed9	32	17	them	-PRON-	PRP
cord-288231-vg8bwed9	32	18	a	a	DT
cord-288231-vg8bwed9	32	19	range	range	NN
cord-288231-vg8bwed9	32	20	of	of	IN
cord-288231-vg8bwed9	32	21	novel	novel	JJ
cord-288231-vg8bwed9	32	22	tools	tool	NNS
cord-288231-vg8bwed9	32	23	are	be	VBP
cord-288231-vg8bwed9	32	24	available	available	JJ
cord-288231-vg8bwed9	32	25	to	to	TO
cord-288231-vg8bwed9	32	26	study	study	VB
cord-288231-vg8bwed9	32	27	virus	virus	NN
cord-288231-vg8bwed9	32	28	-	-	HYPH
cord-288231-vg8bwed9	32	29	host	host	NN
cord-288231-vg8bwed9	32	30	interactions	interaction	NNS
cord-288231-vg8bwed9	32	31	at	at	IN
cord-288231-vg8bwed9	32	32	the	the	DT
cord-288231-vg8bwed9	32	33	molecular	molecular	JJ
cord-288231-vg8bwed9	32	34	level	level	NN
cord-288231-vg8bwed9	32	35	.	.	.
cord-288231-vg8bwed9	33	1	This	this	DT
cord-288231-vg8bwed9	33	2	progress	progress	NN
cord-288231-vg8bwed9	33	3	,	,	,
cord-288231-vg8bwed9	33	4	together	together	RB
cord-288231-vg8bwed9	33	5	with	with	IN
cord-288231-vg8bwed9	33	6	advances	advance	NNS
cord-288231-vg8bwed9	33	7	in	in	IN
cord-288231-vg8bwed9	33	8	high	high	JJ
cord-288231-vg8bwed9	33	9	-	-	HYPH
cord-288231-vg8bwed9	33	10	throughput	throughput	NN
cord-288231-vg8bwed9	33	11	sequencing	sequencing	NN
cord-288231-vg8bwed9	33	12	technology	technology	NN
cord-288231-vg8bwed9	33	13	and	and	CC
cord-288231-vg8bwed9	33	14	,	,	,
cord-288231-vg8bwed9	33	15	not	not	RB
cord-288231-vg8bwed9	33	16	least	least	JJS
cord-288231-vg8bwed9	33	17	,	,	,
cord-288231-vg8bwed9	33	18	in	in	IN
cord-288231-vg8bwed9	33	19	(	(	-LRB-
cord-288231-vg8bwed9	33	20	bio)informatics	bio)informatic	NNS
cord-288231-vg8bwed9	33	21	and	and	CC
cord-288231-vg8bwed9	33	22	statistics	statistic	NNS
cord-288231-vg8bwed9	33	23	,	,	,
cord-288231-vg8bwed9	33	24	allows	allow	VBZ
cord-288231-vg8bwed9	33	25	us	-PRON-	PRP
cord-288231-vg8bwed9	33	26	to	to	TO
cord-288231-vg8bwed9	33	27	analyze	analyze	VB
cord-288231-vg8bwed9	33	28	the	the	DT
cord-288231-vg8bwed9	33	29	'	'	''
cord-288231-vg8bwed9	33	30	'	'	``
cord-288231-vg8bwed9	33	31	genomewide	genomewide	NNP
cord-288231-vg8bwed9	33	32	'	'	''
cord-288231-vg8bwed9	33	33	'	'	''
cord-288231-vg8bwed9	33	34	networks	network	NNS
cord-288231-vg8bwed9	33	35	of	of	IN
cord-288231-vg8bwed9	33	36	gene	gene	NN
cord-288231-vg8bwed9	33	37	interactions	interaction	NNS
cord-288231-vg8bwed9	33	38	that	that	WDT
cord-288231-vg8bwed9	33	39	control	control	VBP
cord-288231-vg8bwed9	33	40	the	the	DT
cord-288231-vg8bwed9	33	41	host	host	NN
cord-288231-vg8bwed9	33	42	response	response	NN
cord-288231-vg8bwed9	33	43	to	to	IN
cord-288231-vg8bwed9	33	44	pathogens	pathogen	NNS
cord-288231-vg8bwed9	33	45	.	.	.
cord-288231-vg8bwed9	34	1	By	by	IN
cord-288231-vg8bwed9	34	2	comparing	compare	VBG
cord-288231-vg8bwed9	34	3	and	and	CC
cord-288231-vg8bwed9	34	4	contrasting	contrast	VBG
cord-288231-vg8bwed9	34	5	the	the	DT
cord-288231-vg8bwed9	34	6	outcomes	outcome	NNS
cord-288231-vg8bwed9	34	7	of	of	IN
cord-288231-vg8bwed9	34	8	infection	infection	NN
cord-288231-vg8bwed9	34	9	with	with	IN
cord-288231-vg8bwed9	34	10	closely	closely	RB
cord-288231-vg8bwed9	34	11	related	related	JJ
cord-288231-vg8bwed9	34	12	pathogens	pathogen	NNS
cord-288231-vg8bwed9	34	13	in	in	IN
cord-288231-vg8bwed9	34	14	different	different	JJ
cord-288231-vg8bwed9	34	15	but	but	CC
cord-288231-vg8bwed9	34	16	related	related	JJ
cord-288231-vg8bwed9	34	17	host	host	NN
cord-288231-vg8bwed9	34	18	species	specie	NNS
cord-288231-vg8bwed9	34	19	,	,	,
cord-288231-vg8bwed9	34	20	we	-PRON-	PRP
cord-288231-vg8bwed9	34	21	can	can	MD
cord-288231-vg8bwed9	34	22	further	further	RB
cord-288231-vg8bwed9	34	23	delineate	delineate	VB
cord-288231-vg8bwed9	34	24	the	the	DT
cord-288231-vg8bwed9	34	25	various	various	JJ
cord-288231-vg8bwed9	34	26	host	host	NN
cord-288231-vg8bwed9	34	27	pathways	pathway	NNS
cord-288231-vg8bwed9	34	28	involved	involve	VBN
cord-288231-vg8bwed9	34	29	in	in	IN
cord-288231-vg8bwed9	34	30	the	the	DT
cord-288231-vg8bwed9	34	31	different	different	JJ
cord-288231-vg8bwed9	34	32	outcomes	outcome	NNS
cord-288231-vg8bwed9	34	33	.	.	.
cord-288231-vg8bwed9	35	1	The	the	DT
cord-288231-vg8bwed9	35	2	power	power	NN
cord-288231-vg8bwed9	35	3	of	of	IN
cord-288231-vg8bwed9	35	4	this	this	DT
cord-288231-vg8bwed9	35	5	approach	approach	NN
cord-288231-vg8bwed9	35	6	was	be	VBD
cord-288231-vg8bwed9	35	7	nicely	nicely	RB
cord-288231-vg8bwed9	35	8	demonstrated	demonstrate	VBN
cord-288231-vg8bwed9	35	9	for	for	IN
cord-288231-vg8bwed9	35	10	SIV	SIV	NNP
cord-288231-vg8bwed9	35	11	infection	infection	NN
cord-288231-vg8bwed9	35	12	of	of	IN
cord-288231-vg8bwed9	35	13	various	various	JJ
cord-288231-vg8bwed9	35	14	primate	primate	JJ
cord-288231-vg8bwed9	35	15	host	host	NN
cord-288231-vg8bwed9	35	16	species	specie	NNS
cord-288231-vg8bwed9	35	17	.	.	.
cord-288231-vg8bwed9	36	1	Natural	natural	JJ
cord-288231-vg8bwed9	36	2	reservoir	reservoir	NN
cord-288231-vg8bwed9	36	3	hosts	host	NNS
cord-288231-vg8bwed9	36	4	of	of	IN
cord-288231-vg8bwed9	36	5	SIV	SIV	NNP
cord-288231-vg8bwed9	36	6	do	do	VBP
cord-288231-vg8bwed9	36	7	not	not	RB
cord-288231-vg8bwed9	36	8	develop	develop	VB
cord-288231-vg8bwed9	36	9	AIDS	AIDS	NNP
cord-288231-vg8bwed9	36	10	upon	upon	IN
cord-288231-vg8bwed9	36	11	infection	infection	NN
cord-288231-vg8bwed9	36	12	,	,	,
cord-288231-vg8bwed9	36	13	whereas	whereas	IN
cord-288231-vg8bwed9	36	14	non	non	JJ
cord-288231-vg8bwed9	36	15	-	-	JJ
cord-288231-vg8bwed9	36	16	natural	natural	JJ
cord-288231-vg8bwed9	36	17	hosts	host	NNS
cord-288231-vg8bwed9	36	18	,	,	,
cord-288231-vg8bwed9	36	19	such	such	JJ
cord-288231-vg8bwed9	36	20	as	as	IN
cord-288231-vg8bwed9	36	21	rhesus	rhesu	NNS
cord-288231-vg8bwed9	36	22	macaques	macaque	NNS
cord-288231-vg8bwed9	36	23	and	and	CC
cord-288231-vg8bwed9	36	24	pig	pig	NN
cord-288231-vg8bwed9	36	25	-	-	HYPH
cord-288231-vg8bwed9	36	26	tailed	tail	VBN
cord-288231-vg8bwed9	36	27	macaques	macaque	NNS
cord-288231-vg8bwed9	36	28	,	,	,
cord-288231-vg8bwed9	36	29	when	when	WRB
cord-288231-vg8bwed9	36	30	infected	infect	VBN
cord-288231-vg8bwed9	36	31	experimentally	experimentally	RB
cord-288231-vg8bwed9	36	32	with	with	IN
cord-288231-vg8bwed9	36	33	SIV	SIV	NNP
cord-288231-vg8bwed9	36	34	,	,	,
cord-288231-vg8bwed9	36	35	develop	develop	VB
cord-288231-vg8bwed9	36	36	AIDS	AIDS	NNP
cord-288231-vg8bwed9	36	37	in	in	IN
cord-288231-vg8bwed9	36	38	a	a	DT
cord-288231-vg8bwed9	36	39	similar	similar	JJ
cord-288231-vg8bwed9	36	40	manner	manner	NN
cord-288231-vg8bwed9	36	41	to	to	IN
cord-288231-vg8bwed9	36	42	HIV	HIV	NNP
cord-288231-vg8bwed9	36	43	-	-	HYPH
cord-288231-vg8bwed9	36	44	infected	infect	VBN
cord-288231-vg8bwed9	36	45	humans	human	NNS
cord-288231-vg8bwed9	36	46	.	.	.
cord-288231-vg8bwed9	37	1	Transcriptional	transcriptional	JJ
cord-288231-vg8bwed9	37	2	profiling	profiling	NN
cord-288231-vg8bwed9	37	3	indicates	indicate	VBZ
cord-288231-vg8bwed9	37	4	that	that	IN
cord-288231-vg8bwed9	37	5	SIV	SIV	NNP
cord-288231-vg8bwed9	37	6	infection	infection	NN
cord-288231-vg8bwed9	37	7	of	of	IN
cord-288231-vg8bwed9	37	8	these	these	DT
cord-288231-vg8bwed9	37	9	species	specie	NNS
cord-288231-vg8bwed9	37	10	produces	produce	VBZ
cord-288231-vg8bwed9	37	11	a	a	DT
cord-288231-vg8bwed9	37	12	distinctive	distinctive	JJ
cord-288231-vg8bwed9	37	13	host	host	NN
cord-288231-vg8bwed9	37	14	response	response	NN
cord-288231-vg8bwed9	37	15	[	[	-LRB-
cord-288231-vg8bwed9	37	16	6	6	CD
cord-288231-vg8bwed9	37	17	]	]	-RRB-
cord-288231-vg8bwed9	37	18	.	.	.
cord-288231-vg8bwed9	38	1	SIV	SIV	NNP
cord-288231-vg8bwed9	38	2	-	-	HYPH
cord-288231-vg8bwed9	38	3	infected	infect	VBN
cord-288231-vg8bwed9	38	4	primates	primate	NNS
cord-288231-vg8bwed9	38	5	with	with	IN
cord-288231-vg8bwed9	38	6	symptoms	symptom	NNS
cord-288231-vg8bwed9	38	7	of	of	IN
cord-288231-vg8bwed9	38	8	AIDS	AIDS	NNP
cord-288231-vg8bwed9	38	9	have	have	VBP
cord-288231-vg8bwed9	38	10	a	a	DT
cord-288231-vg8bwed9	38	11	high	high	JJ
cord-288231-vg8bwed9	38	12	viral	viral	JJ
cord-288231-vg8bwed9	38	13	load	load	NN
cord-288231-vg8bwed9	38	14	,	,	,
cord-288231-vg8bwed9	38	15	immune	immune	JJ
cord-288231-vg8bwed9	38	16	activation	activation	NN
cord-288231-vg8bwed9	38	17	,	,	,
cord-288231-vg8bwed9	38	18	and	and	CC
cord-288231-vg8bwed9	38	19	loss	loss	NN
cord-288231-vg8bwed9	38	20	of	of	IN
cord-288231-vg8bwed9	38	21	certain	certain	JJ
cord-288231-vg8bwed9	38	22	types	type	NNS
cord-288231-vg8bwed9	38	23	of	of	IN
cord-288231-vg8bwed9	38	24	T	t	NN
cord-288231-vg8bwed9	38	25	cells	cell	NNS
cord-288231-vg8bwed9	38	26	,	,	,
cord-288231-vg8bwed9	38	27	whereas	whereas	IN
cord-288231-vg8bwed9	38	28	SIVinfected	sivinfected	JJ
cord-288231-vg8bwed9	38	29	sooty	sooty	JJ
cord-288231-vg8bwed9	38	30	mangabeys	mangabeys	NNP
cord-288231-vg8bwed9	38	31	(	(	-LRB-
cord-288231-vg8bwed9	38	32	the	the	DT
cord-288231-vg8bwed9	38	33	species	specie	NNS
cord-288231-vg8bwed9	38	34	from	from	IN
cord-288231-vg8bwed9	38	35	which	which	WDT
cord-288231-vg8bwed9	38	36	HIV-2	HIV-2	NNP
cord-288231-vg8bwed9	38	37	is	be	VBZ
cord-288231-vg8bwed9	38	38	thought	think	VBN
cord-288231-vg8bwed9	38	39	to	to	TO
cord-288231-vg8bwed9	38	40	have	have	VB
cord-288231-vg8bwed9	38	41	originated	originate	VBN
cord-288231-vg8bwed9	38	42	)	)	-RRB-
cord-288231-vg8bwed9	38	43	have	have	VBP
cord-288231-vg8bwed9	38	44	substantially	substantially	RB
cord-288231-vg8bwed9	38	45	lower	low	JJR
cord-288231-vg8bwed9	38	46	levels	level	NNS
cord-288231-vg8bwed9	38	47	of	of	IN
cord-288231-vg8bwed9	38	48	innate	innate	JJ
cord-288231-vg8bwed9	38	49	immune	immune	JJ
cord-288231-vg8bwed9	38	50	activation	activation	NN
cord-288231-vg8bwed9	38	51	than	than	IN
cord-288231-vg8bwed9	38	52	the	the	DT
cord-288231-vg8bwed9	38	53	symptomatic	symptomatic	JJ
cord-288231-vg8bwed9	38	54	primates	primate	NNS
cord-288231-vg8bwed9	38	55	,	,	,
cord-288231-vg8bwed9	38	56	partly	partly	RB
cord-288231-vg8bwed9	38	57	due	due	IN
cord-288231-vg8bwed9	38	58	to	to	IN
cord-288231-vg8bwed9	38	59	the	the	DT
cord-288231-vg8bwed9	38	60	production	production	NN
cord-288231-vg8bwed9	38	61	of	of	IN
cord-288231-vg8bwed9	38	62	less	less	JJR
cord-288231-vg8bwed9	38	63	interferon	interferon	NN
cord-288231-vg8bwed9	38	64	-	-	HYPH
cord-288231-vg8bwed9	38	65	a	a	NN
cord-288231-vg8bwed9	38	66	by	by	IN
cord-288231-vg8bwed9	38	67	plasmacytoid	plasmacytoid	NNP
cord-288231-vg8bwed9	38	68	dendritic	dendritic	JJ
cord-288231-vg8bwed9	38	69	cells	cell	NNS
cord-288231-vg8bwed9	38	70	in	in	IN
cord-288231-vg8bwed9	38	71	response	response	NN
cord-288231-vg8bwed9	38	72	to	to	IN
cord-288231-vg8bwed9	38	73	SIV	SIV	NNP
cord-288231-vg8bwed9	38	74	and	and	CC
cord-288231-vg8bwed9	38	75	other	other	JJ
cord-288231-vg8bwed9	38	76	Toll	Toll	NNP
cord-288231-vg8bwed9	38	77	-	-	HYPH
cord-288231-vg8bwed9	38	78	like	like	JJ
cord-288231-vg8bwed9	38	79	receptor	receptor	NN
cord-288231-vg8bwed9	38	80	ligands	ligand	NNS
cord-288231-vg8bwed9	38	81	[	[	-LRB-
cord-288231-vg8bwed9	38	82	7	7	CD
cord-288231-vg8bwed9	38	83	]	]	-RRB-
cord-288231-vg8bwed9	38	84	.	.	.
cord-288231-vg8bwed9	39	1	Identification	identification	NN
cord-288231-vg8bwed9	39	2	of	of	IN
cord-288231-vg8bwed9	39	3	host	host	NN
cord-288231-vg8bwed9	39	4	factors	factor	NNS
cord-288231-vg8bwed9	39	5	that	that	WDT
cord-288231-vg8bwed9	39	6	restrict	restrict	VBP
cord-288231-vg8bwed9	39	7	HIV	HIV	NNP
cord-288231-vg8bwed9	39	8	infection	infection	NN
cord-288231-vg8bwed9	39	9	may	may	MD
cord-288231-vg8bwed9	39	10	aid	aid	VB
cord-288231-vg8bwed9	39	11	the	the	DT
cord-288231-vg8bwed9	39	12	development	development	NN
cord-288231-vg8bwed9	39	13	of	of	IN
cord-288231-vg8bwed9	39	14	effective	effective	JJ
cord-288231-vg8bwed9	39	15	intervention	intervention	NN
cord-288231-vg8bwed9	39	16	strategies	strategy	NNS
cord-288231-vg8bwed9	39	17	.	.	.
cord-288231-vg8bwed9	40	1	Below	below	RB
cord-288231-vg8bwed9	40	2	,	,	,
cord-288231-vg8bwed9	40	3	we	-PRON-	PRP
cord-288231-vg8bwed9	40	4	elaborate	elaborate	VBP
cord-288231-vg8bwed9	40	5	on	on	IN
cord-288231-vg8bwed9	40	6	two	two	CD
cord-288231-vg8bwed9	40	7	other	other	JJ
cord-288231-vg8bwed9	40	8	examples	example	NNS
cord-288231-vg8bwed9	40	9	of	of	IN
cord-288231-vg8bwed9	40	10	recent	recent	JJ
cord-288231-vg8bwed9	40	11	important	important	JJ
cord-288231-vg8bwed9	40	12	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	40	13	events	event	NNS
cord-288231-vg8bwed9	40	14	that	that	WDT
cord-288231-vg8bwed9	40	15	led	lead	VBD
cord-288231-vg8bwed9	40	16	to	to	IN
cord-288231-vg8bwed9	40	17	sustained	sustained	JJ
cord-288231-vg8bwed9	40	18	virus	virus	NN
cord-288231-vg8bwed9	40	19	transmission	transmission	NN
cord-288231-vg8bwed9	40	20	in	in	IN
cord-288231-vg8bwed9	40	21	the	the	DT
cord-288231-vg8bwed9	40	22	human	human	JJ
cord-288231-vg8bwed9	40	23	host	host	NN
cord-288231-vg8bwed9	40	24	,	,	,
cord-288231-vg8bwed9	40	25	and	and	CC
cord-288231-vg8bwed9	40	26	the	the	DT
cord-288231-vg8bwed9	40	27	role	role	NN
cord-288231-vg8bwed9	40	28	that	that	WDT
cord-288231-vg8bwed9	40	29	genomics	genomic	NNS
cord-288231-vg8bwed9	40	30	has	have	VBZ
cord-288231-vg8bwed9	40	31	played	play	VBN
cord-288231-vg8bwed9	40	32	in	in	IN
cord-288231-vg8bwed9	40	33	the	the	DT
cord-288231-vg8bwed9	40	34	elucidation	elucidation	NN
cord-288231-vg8bwed9	40	35	of	of	IN
cord-288231-vg8bwed9	40	36	their	-PRON-	PRP$
cord-288231-vg8bwed9	40	37	pathogenesis	pathogenesis	NN
cord-288231-vg8bwed9	40	38	thus	thus	RB
cord-288231-vg8bwed9	40	39	far	far	RB
cord-288231-vg8bwed9	40	40	.	.	.
cord-288231-vg8bwed9	41	1	Influenza	influenza	NN
cord-288231-vg8bwed9	41	2	is	be	VBZ
cord-288231-vg8bwed9	41	3	caused	cause	VBN
cord-288231-vg8bwed9	41	4	by	by	IN
cord-288231-vg8bwed9	41	5	RNA	RNA	NNP
cord-288231-vg8bwed9	41	6	viruses	virus	NNS
cord-288231-vg8bwed9	41	7	of	of	IN
cord-288231-vg8bwed9	41	8	the	the	DT
cord-288231-vg8bwed9	41	9	Orthomyxoviridae	Orthomyxoviridae	NNP
cord-288231-vg8bwed9	41	10	family	family	NN
cord-288231-vg8bwed9	41	11	.	.	.
cord-288231-vg8bwed9	42	1	Whereas	whereas	IN
cord-288231-vg8bwed9	42	2	fever	fever	NN
cord-288231-vg8bwed9	42	3	and	and	CC
cord-288231-vg8bwed9	42	4	coughs	cough	NNS
cord-288231-vg8bwed9	42	5	are	be	VBP
cord-288231-vg8bwed9	42	6	the	the	DT
cord-288231-vg8bwed9	42	7	most	most	RBS
cord-288231-vg8bwed9	42	8	frequent	frequent	JJ
cord-288231-vg8bwed9	42	9	symptoms	symptom	NNS
cord-288231-vg8bwed9	42	10	,	,	,
cord-288231-vg8bwed9	42	11	in	in	IN
cord-288231-vg8bwed9	42	12	more	more	RBR
cord-288231-vg8bwed9	42	13	serious	serious	JJ
cord-288231-vg8bwed9	42	14	cases	case	NNS
cord-288231-vg8bwed9	42	15	a	a	DT
cord-288231-vg8bwed9	42	16	fatal	fatal	JJ
cord-288231-vg8bwed9	42	17	pneumonia	pneumonia	NN
cord-288231-vg8bwed9	42	18	can	can	MD
cord-288231-vg8bwed9	42	19	develop	develop	VB
cord-288231-vg8bwed9	42	20	,	,	,
cord-288231-vg8bwed9	42	21	particularly	particularly	RB
cord-288231-vg8bwed9	42	22	in	in	IN
cord-288231-vg8bwed9	42	23	the	the	DT
cord-288231-vg8bwed9	42	24	young	young	JJ
cord-288231-vg8bwed9	42	25	and	and	CC
cord-288231-vg8bwed9	42	26	the	the	DT
cord-288231-vg8bwed9	42	27	elderly	elderly	JJ
cord-288231-vg8bwed9	42	28	.	.	.
cord-288231-vg8bwed9	43	1	Typically	typically	RB
cord-288231-vg8bwed9	43	2	,	,	,
cord-288231-vg8bwed9	43	3	influenza	influenza	NN
cord-288231-vg8bwed9	43	4	is	be	VBZ
cord-288231-vg8bwed9	43	5	transmitted	transmit	VBN
cord-288231-vg8bwed9	43	6	through	through	IN
cord-288231-vg8bwed9	43	7	the	the	DT
cord-288231-vg8bwed9	43	8	air	air	NN
cord-288231-vg8bwed9	43	9	by	by	IN
cord-288231-vg8bwed9	43	10	coughs	cough	NNS
cord-288231-vg8bwed9	43	11	or	or	CC
cord-288231-vg8bwed9	43	12	sneezes	sneeze	NNS
cord-288231-vg8bwed9	43	13	,	,	,
cord-288231-vg8bwed9	43	14	creating	create	VBG
cord-288231-vg8bwed9	43	15	aerosols	aerosol	NNS
cord-288231-vg8bwed9	43	16	containing	contain	VBG
cord-288231-vg8bwed9	43	17	the	the	DT
cord-288231-vg8bwed9	43	18	virus	virus	NN
cord-288231-vg8bwed9	43	19	;	;	:
cord-288231-vg8bwed9	43	20	but	but	CC
cord-288231-vg8bwed9	43	21	influenza	influenza	NN
cord-288231-vg8bwed9	43	22	can	can	MD
cord-288231-vg8bwed9	43	23	also	also	RB
cord-288231-vg8bwed9	43	24	be	be	VB
cord-288231-vg8bwed9	43	25	transmitted	transmit	VBN
cord-288231-vg8bwed9	43	26	by	by	IN
cord-288231-vg8bwed9	43	27	bird	bird	NN
cord-288231-vg8bwed9	43	28	droppings	dropping	NNS
cord-288231-vg8bwed9	43	29	,	,	,
cord-288231-vg8bwed9	43	30	saliva	saliva	NN
cord-288231-vg8bwed9	43	31	,	,	,
cord-288231-vg8bwed9	43	32	feces	fece	NNS
cord-288231-vg8bwed9	43	33	,	,	,
cord-288231-vg8bwed9	43	34	and	and	CC
cord-288231-vg8bwed9	43	35	blood	blood	NN
cord-288231-vg8bwed9	43	36	.	.	.
cord-288231-vg8bwed9	44	1	Birds	bird	NNS
cord-288231-vg8bwed9	44	2	and	and	CC
cord-288231-vg8bwed9	44	3	pigs	pig	NNS
cord-288231-vg8bwed9	44	4	play	play	VBP
cord-288231-vg8bwed9	44	5	an	an	DT
cord-288231-vg8bwed9	44	6	important	important	JJ
cord-288231-vg8bwed9	44	7	role	role	NN
cord-288231-vg8bwed9	44	8	in	in	IN
cord-288231-vg8bwed9	44	9	the	the	DT
cord-288231-vg8bwed9	44	10	emergence	emergence	NN
cord-288231-vg8bwed9	44	11	of	of	IN
cord-288231-vg8bwed9	44	12	new	new	JJ
cord-288231-vg8bwed9	44	13	influenza	influenza	NN
cord-288231-vg8bwed9	44	14	viruses	virus	NNS
cord-288231-vg8bwed9	44	15	in	in	IN
cord-288231-vg8bwed9	44	16	humans	human	NNS
cord-288231-vg8bwed9	44	17	.	.	.
cord-288231-vg8bwed9	45	1	Fecal	fecal	JJ
cord-288231-vg8bwed9	45	2	sampling	sampling	NN
cord-288231-vg8bwed9	45	3	of	of	IN
cord-288231-vg8bwed9	45	4	migratory	migratory	JJ
cord-288231-vg8bwed9	45	5	birds	bird	NNS
cord-288231-vg8bwed9	45	6	has	have	VBZ
cord-288231-vg8bwed9	45	7	revealed	reveal	VBN
cord-288231-vg8bwed9	45	8	that	that	IN
cord-288231-vg8bwed9	45	9	they	-PRON-	PRP
cord-288231-vg8bwed9	45	10	harbor	harbor	VBP
cord-288231-vg8bwed9	45	11	a	a	DT
cord-288231-vg8bwed9	45	12	large	large	JJ
cord-288231-vg8bwed9	45	13	range	range	NN
cord-288231-vg8bwed9	45	14	of	of	IN
cord-288231-vg8bwed9	45	15	different	different	JJ
cord-288231-vg8bwed9	45	16	subtypes	subtype	NNS
cord-288231-vg8bwed9	45	17	of	of	IN
cord-288231-vg8bwed9	45	18	influenza	influenza	NN
cord-288231-vg8bwed9	45	19	A	a	NN
cord-288231-vg8bwed9	45	20	viruses	virus	NNS
cord-288231-vg8bwed9	45	21	[	[	-LRB-
cord-288231-vg8bwed9	45	22	8	8	CD
cord-288231-vg8bwed9	45	23	]	]	-RRB-
cord-288231-vg8bwed9	45	24	.	.	.
cord-288231-vg8bwed9	46	1	Some	some	DT
cord-288231-vg8bwed9	46	2	wild	wild	JJ
cord-288231-vg8bwed9	46	3	duck	duck	NN
cord-288231-vg8bwed9	46	4	species	specie	NNS
cord-288231-vg8bwed9	46	5	,	,	,
cord-288231-vg8bwed9	46	6	particularly	particularly	RB
cord-288231-vg8bwed9	46	7	mallards	mallard	NNS
cord-288231-vg8bwed9	46	8	,	,	,
cord-288231-vg8bwed9	46	9	are	be	VBP
cord-288231-vg8bwed9	46	10	potential	potential	JJ
cord-288231-vg8bwed9	46	11	long	long	JJ
cord-288231-vg8bwed9	46	12	-	-	HYPH
cord-288231-vg8bwed9	46	13	distance	distance	NN
cord-288231-vg8bwed9	46	14	vectors	vector	NNS
cord-288231-vg8bwed9	46	15	of	of	IN
cord-288231-vg8bwed9	46	16	highly	highly	RB
cord-288231-vg8bwed9	46	17	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	46	18	avian	avian	JJ
cord-288231-vg8bwed9	46	19	influenza	influenza	NN
cord-288231-vg8bwed9	46	20	virus	virus	NN
cord-288231-vg8bwed9	46	21	(	(	-LRB-
cord-288231-vg8bwed9	46	22	H5N1	H5N1	NNP
cord-288231-vg8bwed9	46	23	)	)	-RRB-
cord-288231-vg8bwed9	46	24	,	,	,
cord-288231-vg8bwed9	46	25	whereas	whereas	IN
cord-288231-vg8bwed9	46	26	others	other	NNS
cord-288231-vg8bwed9	46	27	,	,	,
cord-288231-vg8bwed9	46	28	including	include	VBG
cord-288231-vg8bwed9	46	29	diving	diving	JJ
cord-288231-vg8bwed9	46	30	ducks	duck	NNS
cord-288231-vg8bwed9	46	31	,	,	,
cord-288231-vg8bwed9	46	32	are	be	VBP
cord-288231-vg8bwed9	46	33	more	more	RBR
cord-288231-vg8bwed9	46	34	likely	likely	JJ
cord-288231-vg8bwed9	46	35	to	to	TO
cord-288231-vg8bwed9	46	36	act	act	VB
cord-288231-vg8bwed9	46	37	as	as	IN
cord-288231-vg8bwed9	46	38	'	'	''
cord-288231-vg8bwed9	46	39	'	'	``
cord-288231-vg8bwed9	46	40	sentinel	sentinel	NN
cord-288231-vg8bwed9	46	41	'	'	''
cord-288231-vg8bwed9	46	42	'	'	''
cord-288231-vg8bwed9	46	43	species	specie	NNS
cord-288231-vg8bwed9	46	44	that	that	WDT
cord-288231-vg8bwed9	46	45	die	die	VBP
cord-288231-vg8bwed9	46	46	upon	upon	IN
cord-288231-vg8bwed9	46	47	infection	infection	NN
cord-288231-vg8bwed9	46	48	[	[	-LRB-
cord-288231-vg8bwed9	46	49	9	9	CD
cord-288231-vg8bwed9	46	50	]	]	-RRB-
cord-288231-vg8bwed9	46	51	.	.	.
cord-288231-vg8bwed9	47	1	Following	follow	VBG
cord-288231-vg8bwed9	47	2	the	the	DT
cord-288231-vg8bwed9	47	3	introduction	introduction	NN
cord-288231-vg8bwed9	47	4	of	of	IN
cord-288231-vg8bwed9	47	5	a	a	DT
cord-288231-vg8bwed9	47	6	new	new	JJ
cord-288231-vg8bwed9	47	7	pandemic	pandemic	NN
cord-288231-vg8bwed9	47	8	influenza	influenza	NN
cord-288231-vg8bwed9	47	9	A	a	DT
cord-288231-vg8bwed9	47	10	virus	virus	NN
cord-288231-vg8bwed9	47	11	subtype	subtype	NN
cord-288231-vg8bwed9	47	12	from	from	IN
cord-288231-vg8bwed9	47	13	an	an	DT
cord-288231-vg8bwed9	47	14	avian	avian	JJ
cord-288231-vg8bwed9	47	15	reservoir	reservoir	NN
cord-288231-vg8bwed9	47	16	,	,	,
cord-288231-vg8bwed9	47	17	either	either	CC
cord-288231-vg8bwed9	47	18	directly	directly	RB
cord-288231-vg8bwed9	47	19	or	or	CC
cord-288231-vg8bwed9	47	20	via	via	IN
cord-288231-vg8bwed9	47	21	another	another	DT
cord-288231-vg8bwed9	47	22	mammalian	mammalian	JJ
cord-288231-vg8bwed9	47	23	species	specie	NNS
cord-288231-vg8bwed9	47	24	such	such	JJ
cord-288231-vg8bwed9	47	25	as	as	IN
cord-288231-vg8bwed9	47	26	the	the	DT
cord-288231-vg8bwed9	47	27	pig	pig	NN
cord-288231-vg8bwed9	47	28	,	,	,
cord-288231-vg8bwed9	47	29	the	the	DT
cord-288231-vg8bwed9	47	30	virus	virus	NN
cord-288231-vg8bwed9	47	31	may	may	MD
cord-288231-vg8bwed9	47	32	continue	continue	VB
cord-288231-vg8bwed9	47	33	to	to	TO
cord-288231-vg8bwed9	47	34	circulate	circulate	VB
cord-288231-vg8bwed9	47	35	in	in	IN
cord-288231-vg8bwed9	47	36	humans	human	NNS
cord-288231-vg8bwed9	47	37	in	in	IN
cord-288231-vg8bwed9	47	38	subsequent	subsequent	JJ
cord-288231-vg8bwed9	47	39	years	year	NNS
cord-288231-vg8bwed9	47	40	as	as	IN
cord-288231-vg8bwed9	47	41	a	a	DT
cord-288231-vg8bwed9	47	42	seasonal	seasonal	JJ
cord-288231-vg8bwed9	47	43	influenza	influenza	NN
cord-288231-vg8bwed9	47	44	virus	virus	NN
cord-288231-vg8bwed9	47	45	.	.	.
cord-288231-vg8bwed9	48	1	In	in	IN
cord-288231-vg8bwed9	48	2	the	the	DT
cord-288231-vg8bwed9	48	3	past	past	JJ
cord-288231-vg8bwed9	48	4	century	century	NN
cord-288231-vg8bwed9	48	5	,	,	,
cord-288231-vg8bwed9	48	6	three	three	CD
cord-288231-vg8bwed9	48	7	major	major	JJ
cord-288231-vg8bwed9	48	8	influenza	influenza	NN
cord-288231-vg8bwed9	48	9	epidemics	epidemic	NNS
cord-288231-vg8bwed9	48	10	resulted	result	VBD
cord-288231-vg8bwed9	48	11	in	in	IN
cord-288231-vg8bwed9	48	12	the	the	DT
cord-288231-vg8bwed9	48	13	loss	loss	NN
cord-288231-vg8bwed9	48	14	of	of	IN
cord-288231-vg8bwed9	48	15	many	many	JJ
cord-288231-vg8bwed9	48	16	millions	million	NNS
cord-288231-vg8bwed9	48	17	of	of	IN
cord-288231-vg8bwed9	48	18	lives	life	NNS
cord-288231-vg8bwed9	48	19	.	.	.
cord-288231-vg8bwed9	49	1	Spanish	spanish	JJ
cord-288231-vg8bwed9	49	2	flu	flu	NN
cord-288231-vg8bwed9	49	3	alone	alone	RB
cord-288231-vg8bwed9	49	4	caused	cause	VBD
cord-288231-vg8bwed9	49	5	the	the	DT
cord-288231-vg8bwed9	49	6	deaths	death	NNS
cord-288231-vg8bwed9	49	7	of	of	IN
cord-288231-vg8bwed9	49	8	more	more	JJR
cord-288231-vg8bwed9	49	9	than	than	IN
cord-288231-vg8bwed9	49	10	50	50	CD
cord-288231-vg8bwed9	49	11	million	million	CD
cord-288231-vg8bwed9	49	12	people	people	NNS
cord-288231-vg8bwed9	49	13	by	by	IN
cord-288231-vg8bwed9	49	14	the	the	DT
cord-288231-vg8bwed9	49	15	end	end	NN
cord-288231-vg8bwed9	49	16	of	of	IN
cord-288231-vg8bwed9	49	17	World	World	NNP
cord-288231-vg8bwed9	49	18	War	War	NNP
cord-288231-vg8bwed9	49	19	I	I	NNP
cord-288231-vg8bwed9	49	20	in	in	IN
cord-288231-vg8bwed9	49	21	1918	1918	CD
cord-288231-vg8bwed9	49	22	.	.	.
cord-288231-vg8bwed9	50	1	The	the	DT
cord-288231-vg8bwed9	50	2	2009	2009	CD
cord-288231-vg8bwed9	50	3	outbreak	outbreak	NN
cord-288231-vg8bwed9	50	4	of	of	IN
cord-288231-vg8bwed9	50	5	a	a	DT
cord-288231-vg8bwed9	50	6	new	new	JJ
cord-288231-vg8bwed9	50	7	H1N1	H1N1	NNP
cord-288231-vg8bwed9	50	8	virus	virus	NN
cord-288231-vg8bwed9	50	9	(	(	-LRB-
cord-288231-vg8bwed9	50	10	causing	cause	VBG
cord-288231-vg8bwed9	50	11	'	'	''
cord-288231-vg8bwed9	50	12	'	'	``
cord-288231-vg8bwed9	50	13	swine	swine	NN
cord-288231-vg8bwed9	50	14	flu	flu	NN
cord-288231-vg8bwed9	50	15	'	'	''
cord-288231-vg8bwed9	50	16	'	'	''
cord-288231-vg8bwed9	50	17	)	)	-RRB-
cord-288231-vg8bwed9	50	18	that	that	WDT
cord-288231-vg8bwed9	50	19	started	start	VBD
cord-288231-vg8bwed9	50	20	in	in	IN
cord-288231-vg8bwed9	50	21	Mexico	Mexico	NNP
cord-288231-vg8bwed9	50	22	further	further	RB
cord-288231-vg8bwed9	50	23	illustrates	illustrate	VBZ
cord-288231-vg8bwed9	50	24	the	the	DT
cord-288231-vg8bwed9	50	25	pandemic	pandemic	NN
cord-288231-vg8bwed9	50	26	potential	potential	NN
cord-288231-vg8bwed9	50	27	of	of	IN
cord-288231-vg8bwed9	50	28	influenza	influenza	NN
cord-288231-vg8bwed9	50	29	A	a	NN
cord-288231-vg8bwed9	50	30	viruses	virus	NNS
cord-288231-vg8bwed9	50	31	.	.	.
cord-288231-vg8bwed9	51	1	After	after	IN
cord-288231-vg8bwed9	51	2	introduction	introduction	NN
cord-288231-vg8bwed9	51	3	of	of	IN
cord-288231-vg8bwed9	51	4	a	a	DT
cord-288231-vg8bwed9	51	5	new	new	JJ
cord-288231-vg8bwed9	51	6	influenza	influenza	NN
cord-288231-vg8bwed9	51	7	A	a	DT
cord-288231-vg8bwed9	51	8	virus	virus	NN
cord-288231-vg8bwed9	51	9	from	from	IN
cord-288231-vg8bwed9	51	10	an	an	DT
cord-288231-vg8bwed9	51	11	avian	avian	JJ
cord-288231-vg8bwed9	51	12	or	or	CC
cord-288231-vg8bwed9	51	13	porcine	porcine	JJ
cord-288231-vg8bwed9	51	14	reservoir	reservoir	NN
cord-288231-vg8bwed9	51	15	into	into	IN
cord-288231-vg8bwed9	51	16	the	the	DT
cord-288231-vg8bwed9	51	17	human	human	JJ
cord-288231-vg8bwed9	51	18	species	specie	NNS
cord-288231-vg8bwed9	51	19	,	,	,
cord-288231-vg8bwed9	51	20	viral	viral	JJ
cord-288231-vg8bwed9	51	21	genomics	genomic	NNS
cord-288231-vg8bwed9	51	22	studies	study	NNS
cord-288231-vg8bwed9	51	23	are	be	VBP
cord-288231-vg8bwed9	51	24	essential	essential	JJ
cord-288231-vg8bwed9	51	25	to	to	TO
cord-288231-vg8bwed9	51	26	identify	identify	VB
cord-288231-vg8bwed9	51	27	critical	critical	JJ
cord-288231-vg8bwed9	51	28	mutations	mutation	NNS
cord-288231-vg8bwed9	51	29	that	that	WDT
cord-288231-vg8bwed9	51	30	enable	enable	VBP
cord-288231-vg8bwed9	51	31	the	the	DT
cord-288231-vg8bwed9	51	32	circulating	circulate	VBG
cord-288231-vg8bwed9	51	33	virus	virus	NN
cord-288231-vg8bwed9	51	34	to	to	TO
cord-288231-vg8bwed9	51	35	spread	spread	VB
cord-288231-vg8bwed9	51	36	efficiently	efficiently	RB
cord-288231-vg8bwed9	51	37	,	,	,
cord-288231-vg8bwed9	51	38	interact	interact	VB
cord-288231-vg8bwed9	51	39	with	with	IN
cord-288231-vg8bwed9	51	40	different	different	JJ
cord-288231-vg8bwed9	51	41	receptors	receptor	NNS
cord-288231-vg8bwed9	51	42	,	,	,
cord-288231-vg8bwed9	51	43	and	and	CC
cord-288231-vg8bwed9	51	44	cause	cause	VB
cord-288231-vg8bwed9	51	45	disease	disease	NN
cord-288231-vg8bwed9	51	46	in	in	IN
cord-288231-vg8bwed9	51	47	the	the	DT
cord-288231-vg8bwed9	51	48	new	new	JJ
cord-288231-vg8bwed9	51	49	host	host	NN
cord-288231-vg8bwed9	51	50	.	.	.
cord-288231-vg8bwed9	52	1	For	for	IN
cord-288231-vg8bwed9	52	2	example	example	NN
cord-288231-vg8bwed9	52	3	,	,	,
cord-288231-vg8bwed9	52	4	the	the	DT
cord-288231-vg8bwed9	52	5	importance	importance	NN
cord-288231-vg8bwed9	52	6	of	of	IN
cord-288231-vg8bwed9	52	7	residue	residue	NN
cord-288231-vg8bwed9	52	8	627	627	CD
cord-288231-vg8bwed9	52	9	of	of	IN
cord-288231-vg8bwed9	52	10	the	the	DT
cord-288231-vg8bwed9	52	11	PB2	PB2	NNP
cord-288231-vg8bwed9	52	12	protein	protein	NN
cord-288231-vg8bwed9	52	13	of	of	IN
cord-288231-vg8bwed9	52	14	the	the	DT
cord-288231-vg8bwed9	52	15	viral	viral	JJ
cord-288231-vg8bwed9	52	16	polymerase	polymerase	NN
cord-288231-vg8bwed9	52	17	in	in	IN
cord-288231-vg8bwed9	52	18	determining	determine	VBG
cord-288231-vg8bwed9	52	19	species	specie	NNS
cord-288231-vg8bwed9	52	20	restriction	restriction	NN
cord-288231-vg8bwed9	52	21	has	have	VBZ
cord-288231-vg8bwed9	52	22	been	be	VBN
cord-288231-vg8bwed9	52	23	demonstrated	demonstrate	VBN
cord-288231-vg8bwed9	52	24	through	through	IN
cord-288231-vg8bwed9	52	25	these	these	DT
cord-288231-vg8bwed9	52	26	kinds	kind	NNS
cord-288231-vg8bwed9	52	27	of	of	IN
cord-288231-vg8bwed9	52	28	approaches	approach	NNS
cord-288231-vg8bwed9	52	29	[	[	-LRB-
cord-288231-vg8bwed9	52	30	10	10	CD
cord-288231-vg8bwed9	52	31	]	]	-RRB-
cord-288231-vg8bwed9	52	32	.	.	.
cord-288231-vg8bwed9	53	1	Furthermore	furthermore	RB
cord-288231-vg8bwed9	53	2	,	,	,
cord-288231-vg8bwed9	53	3	changes	change	NNS
cord-288231-vg8bwed9	53	4	in	in	IN
cord-288231-vg8bwed9	53	5	the	the	DT
cord-288231-vg8bwed9	53	6	hemagglutinin	hemagglutinin	NN
cord-288231-vg8bwed9	53	7	molecules	molecule	NNS
cord-288231-vg8bwed9	53	8	may	may	MD
cord-288231-vg8bwed9	53	9	allow	allow	VB
cord-288231-vg8bwed9	53	10	influenza	influenza	NN
cord-288231-vg8bwed9	53	11	A	a	DT
cord-288231-vg8bwed9	53	12	viruses	virus	NNS
cord-288231-vg8bwed9	53	13	to	to	TO
cord-288231-vg8bwed9	53	14	switch	switch	VB
cord-288231-vg8bwed9	53	15	receptor	receptor	NN
cord-288231-vg8bwed9	53	16	specificity	specificity	NN
cord-288231-vg8bwed9	53	17	.	.	.
cord-288231-vg8bwed9	54	1	The	the	DT
cord-288231-vg8bwed9	54	2	hemagglutinin	hemagglutinin	NN
cord-288231-vg8bwed9	54	3	of	of	IN
cord-288231-vg8bwed9	54	4	avian	avian	JJ
cord-288231-vg8bwed9	54	5	H5N1	H5N1	NNP
cord-288231-vg8bwed9	54	6	influenza	influenza	NN
cord-288231-vg8bwed9	54	7	viruses	virus	NNS
cord-288231-vg8bwed9	54	8	preferentially	preferentially	RB
cord-288231-vg8bwed9	54	9	binds	bind	VBZ
cord-288231-vg8bwed9	54	10	to	to	IN
cord-288231-vg8bwed9	54	11	oligosaccharides	oligosaccharide	NNS
cord-288231-vg8bwed9	54	12	that	that	WDT
cord-288231-vg8bwed9	54	13	terminate	terminate	VBP
cord-288231-vg8bwed9	54	14	with	with	IN
cord-288231-vg8bwed9	54	15	a	a	DT
cord-288231-vg8bwed9	54	16	sialic	sialic	JJ
cord-288231-vg8bwed9	54	17	acid	acid	NN
cord-288231-vg8bwed9	54	18	-	-	:
cord-288231-vg8bwed9	54	19	a-2,3-Gal	a-2,3-gal	NN
cord-288231-vg8bwed9	54	20	disaccharide	disaccharide	NN
cord-288231-vg8bwed9	54	21	,	,	,
cord-288231-vg8bwed9	54	22	whereas	whereas	IN
cord-288231-vg8bwed9	54	23	the	the	DT
cord-288231-vg8bwed9	54	24	hemagglutinins	hemagglutinin	NNS
cord-288231-vg8bwed9	54	25	of	of	IN
cord-288231-vg8bwed9	54	26	mammalian	mammalian	JJ
cord-288231-vg8bwed9	54	27	influenza	influenza	NN
cord-288231-vg8bwed9	54	28	A	a	DT
cord-288231-vg8bwed9	54	29	viruses	virus	NNS
cord-288231-vg8bwed9	54	30	prefer	prefer	VBP
cord-288231-vg8bwed9	54	31	oligosaccharides	oligosaccharide	NNS
cord-288231-vg8bwed9	54	32	that	that	WDT
cord-288231-vg8bwed9	54	33	terminate	terminate	VBP
cord-288231-vg8bwed9	54	34	with	with	IN
cord-288231-vg8bwed9	54	35	sialic	sialic	JJ
cord-288231-vg8bwed9	54	36	acid	acid	NN
cord-288231-vg8bwed9	54	37	-	-	:
cord-288231-vg8bwed9	54	38	a-2,6-Gal	a-2,6-gal	CD
cord-288231-vg8bwed9	55	1	(	(	-LRB-
cord-288231-vg8bwed9	55	2	Figure	figure	NN
cord-288231-vg8bwed9	55	3	1	1	CD
cord-288231-vg8bwed9	55	4	)	)	-RRB-
cord-288231-vg8bwed9	55	5	.	.	.
cord-288231-vg8bwed9	56	1	Fatal	fatal	JJ
cord-288231-vg8bwed9	56	2	viral	viral	JJ
cord-288231-vg8bwed9	56	3	pneumonia	pneumonia	NN
cord-288231-vg8bwed9	56	4	in	in	IN
cord-288231-vg8bwed9	56	5	humans	human	NNS
cord-288231-vg8bwed9	56	6	infected	infect	VBN
cord-288231-vg8bwed9	56	7	with	with	IN
cord-288231-vg8bwed9	56	8	avian	avian	JJ
cord-288231-vg8bwed9	56	9	H5N1	H5N1	NNP
cord-288231-vg8bwed9	56	10	viruses	virus	NNS
cord-288231-vg8bwed9	56	11	is	be	VBZ
cord-288231-vg8bwed9	56	12	partly	partly	RB
cord-288231-vg8bwed9	56	13	due	due	JJ
cord-288231-vg8bwed9	56	14	to	to	IN
cord-288231-vg8bwed9	56	15	the	the	DT
cord-288231-vg8bwed9	56	16	ability	ability	NN
cord-288231-vg8bwed9	56	17	of	of	IN
cord-288231-vg8bwed9	56	18	these	these	DT
cord-288231-vg8bwed9	56	19	viruses	virus	NNS
cord-288231-vg8bwed9	56	20	to	to	TO
cord-288231-vg8bwed9	56	21	attach	attach	VB
cord-288231-vg8bwed9	56	22	to	to	TO
cord-288231-vg8bwed9	56	23	and	and	CC
cord-288231-vg8bwed9	56	24	replicate	replicate	VB
cord-288231-vg8bwed9	56	25	in	in	IN
cord-288231-vg8bwed9	56	26	the	the	DT
cord-288231-vg8bwed9	56	27	cells	cell	NNS
cord-288231-vg8bwed9	56	28	of	of	IN
cord-288231-vg8bwed9	56	29	the	the	DT
cord-288231-vg8bwed9	56	30	lower	low	JJR
cord-288231-vg8bwed9	56	31	respiratory	respiratory	JJ
cord-288231-vg8bwed9	56	32	tract	tract	NN
cord-288231-vg8bwed9	56	33	,	,	,
cord-288231-vg8bwed9	56	34	which	which	WDT
cord-288231-vg8bwed9	56	35	have	have	VBP
cord-288231-vg8bwed9	56	36	oligosaccharides	oligosaccharide	NNS
cord-288231-vg8bwed9	56	37	that	that	WDT
cord-288231-vg8bwed9	56	38	terminate	terminate	VBP
cord-288231-vg8bwed9	56	39	in	in	IN
cord-288231-vg8bwed9	56	40	sialic	sialic	JJ
cord-288231-vg8bwed9	56	41	acid	acid	NN
cord-288231-vg8bwed9	56	42	-	-	:
cord-288231-vg8bwed9	56	43	a-2,3-Gal	a-2,3-Gal	NNS
cord-288231-vg8bwed9	56	44	disaccharide	disaccharide	NN
cord-288231-vg8bwed9	56	45	[	[	-LRB-
cord-288231-vg8bwed9	56	46	11	11	CD
cord-288231-vg8bwed9	56	47	,	,	,
cord-288231-vg8bwed9	56	48	12	12	CD
cord-288231-vg8bwed9	56	49	]	]	-RRB-
cord-288231-vg8bwed9	56	50	.	.	.
cord-288231-vg8bwed9	57	1	The	the	DT
cord-288231-vg8bwed9	57	2	sequence	sequence	NN
cord-288231-vg8bwed9	57	3	of	of	IN
cord-288231-vg8bwed9	57	4	the	the	DT
cord-288231-vg8bwed9	57	5	hemagglutinin	hemagglutinin	NN
cord-288231-vg8bwed9	57	6	protein	protein	NN
cord-288231-vg8bwed9	57	7	may	may	MD
cord-288231-vg8bwed9	57	8	also	also	RB
cord-288231-vg8bwed9	57	9	affect	affect	VB
cord-288231-vg8bwed9	57	10	its	-PRON-	PRP$
cord-288231-vg8bwed9	57	11	binding	bind	VBG
cord-288231-vg8bwed9	57	12	affinity	affinity	NN
cord-288231-vg8bwed9	57	13	for	for	IN
cord-288231-vg8bwed9	57	14	neutralizing	neutralize	VBG
cord-288231-vg8bwed9	57	15	antibodies	antibody	NNS
cord-288231-vg8bwed9	57	16	.	.	.
cord-288231-vg8bwed9	58	1	Understanding	understand	VBG
cord-288231-vg8bwed9	58	2	the	the	DT
cord-288231-vg8bwed9	58	3	relationship	relationship	NN
cord-288231-vg8bwed9	58	4	between	between	IN
cord-288231-vg8bwed9	58	5	genetic	genetic	JJ
cord-288231-vg8bwed9	58	6	diversity	diversity	NN
cord-288231-vg8bwed9	58	7	and	and	CC
cord-288231-vg8bwed9	58	8	antigenic	antigenic	JJ
cord-288231-vg8bwed9	58	9	properties	property	NNS
cord-288231-vg8bwed9	58	10	of	of	IN
cord-288231-vg8bwed9	58	11	these	these	DT
cord-288231-vg8bwed9	58	12	viruses	virus	NNS
cord-288231-vg8bwed9	58	13	[	[	-LRB-
cord-288231-vg8bwed9	58	14	13	13	CD
cord-288231-vg8bwed9	58	15	]	]	-RRB-
cord-288231-vg8bwed9	58	16	may	may	MD
cord-288231-vg8bwed9	58	17	help	help	VB
cord-288231-vg8bwed9	58	18	to	to	TO
cord-288231-vg8bwed9	58	19	predict	predict	VB
cord-288231-vg8bwed9	58	20	the	the	DT
cord-288231-vg8bwed9	58	21	emergence	emergence	NN
cord-288231-vg8bwed9	58	22	of	of	IN
cord-288231-vg8bwed9	58	23	influenza	influenza	NN
cord-288231-vg8bwed9	58	24	viruses	virus	NNS
cord-288231-vg8bwed9	58	25	and	and	CC
cord-288231-vg8bwed9	58	26	to	to	TO
cord-288231-vg8bwed9	58	27	develop	develop	VB
cord-288231-vg8bwed9	58	28	effective	effective	JJ
cord-288231-vg8bwed9	58	29	vaccines	vaccine	NNS
cord-288231-vg8bwed9	58	30	.	.	.
cord-288231-vg8bwed9	59	1	Microarray	Microarray	NNP
cord-288231-vg8bwed9	59	2	-	-	HYPH
cord-288231-vg8bwed9	59	3	assisted	assist	VBN
cord-288231-vg8bwed9	59	4	mRNA	mRNA	NNP
cord-288231-vg8bwed9	59	5	expression	expression	NN
cord-288231-vg8bwed9	59	6	profiling	profiling	NN
cord-288231-vg8bwed9	59	7	of	of	IN
cord-288231-vg8bwed9	59	8	emerging	emerge	VBG
cord-288231-vg8bwed9	59	9	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	59	10	viral	viral	JJ
cord-288231-vg8bwed9	59	11	infections	infection	NNS
cord-288231-vg8bwed9	59	12	,	,	,
cord-288231-vg8bwed9	59	13	including	include	VBG
cord-288231-vg8bwed9	59	14	influenza	influenza	NN
cord-288231-vg8bwed9	59	15	A	a	DT
cord-288231-vg8bwed9	59	16	virus	virus	NN
cord-288231-vg8bwed9	59	17	,	,	,
cord-288231-vg8bwed9	59	18	is	be	VBZ
cord-288231-vg8bwed9	59	19	used	use	VBN
cord-288231-vg8bwed9	59	20	to	to	TO
cord-288231-vg8bwed9	59	21	phenotype	phenotype	VB
cord-288231-vg8bwed9	59	22	the	the	DT
cord-288231-vg8bwed9	59	23	host	host	NN
cord-288231-vg8bwed9	59	24	response	response	NN
cord-288231-vg8bwed9	59	25	in	in	IN
cord-288231-vg8bwed9	59	26	great	great	JJ
cord-288231-vg8bwed9	59	27	detail	detail	NN
cord-288231-vg8bwed9	59	28	.	.	.
cord-288231-vg8bwed9	60	1	By	by	IN
cord-288231-vg8bwed9	60	2	comparing	compare	VBG
cord-288231-vg8bwed9	60	3	mRNA	mrna	NN
cord-288231-vg8bwed9	60	4	expression	expression	NN
cord-288231-vg8bwed9	60	5	in	in	IN
cord-288231-vg8bwed9	60	6	individuals	individual	NNS
cord-288231-vg8bwed9	60	7	infected	infect	VBN
cord-288231-vg8bwed9	60	8	with	with	IN
cord-288231-vg8bwed9	60	9	an	an	DT
cord-288231-vg8bwed9	60	10	emerging	emerge	VBG
cord-288231-vg8bwed9	60	11	virus	virus	NN
cord-288231-vg8bwed9	60	12	to	to	IN
cord-288231-vg8bwed9	60	13	expression	expression	NN
cord-288231-vg8bwed9	60	14	in	in	IN
cord-288231-vg8bwed9	60	15	individuals	individual	NNS
cord-288231-vg8bwed9	60	16	infected	infect	VBN
cord-288231-vg8bwed9	60	17	with	with	IN
cord-288231-vg8bwed9	60	18	a	a	DT
cord-288231-vg8bwed9	60	19	related	relate	VBN
cord-288231-vg8bwed9	60	20	established	establish	VBN
cord-288231-vg8bwed9	60	21	virus	virus	NN
cord-288231-vg8bwed9	60	22	,	,	,
cord-288231-vg8bwed9	60	23	researchers	researcher	NNS
cord-288231-vg8bwed9	60	24	can	can	MD
cord-288231-vg8bwed9	60	25	generate	generate	VB
cord-288231-vg8bwed9	60	26	a	a	DT
cord-288231-vg8bwed9	60	27	'	'	''
cord-288231-vg8bwed9	60	28	'	'	''
cord-288231-vg8bwed9	60	29	molecular	molecular	JJ
cord-288231-vg8bwed9	60	30	fingerprint	fingerprint	NN
cord-288231-vg8bwed9	60	31	'	'	''
cord-288231-vg8bwed9	60	32	'	'	''
cord-288231-vg8bwed9	60	33	of	of	IN
cord-288231-vg8bwed9	60	34	the	the	DT
cord-288231-vg8bwed9	60	35	host	host	NN
cord-288231-vg8bwed9	60	36	response	response	NN
cord-288231-vg8bwed9	60	37	genes	gene	NNS
cord-288231-vg8bwed9	60	38	or	or	CC
cord-288231-vg8bwed9	60	39	pathways	pathway	NNS
cord-288231-vg8bwed9	60	40	specifically	specifically	RB
cord-288231-vg8bwed9	60	41	involved	involve	VBN
cord-288231-vg8bwed9	60	42	in	in	IN
cord-288231-vg8bwed9	60	43	the	the	DT
cord-288231-vg8bwed9	60	44	oftenexuberant	oftenexuberant	JJ
cord-288231-vg8bwed9	60	45	host	host	NN
cord-288231-vg8bwed9	60	46	responses	response	NNS
cord-288231-vg8bwed9	60	47	to	to	IN
cord-288231-vg8bwed9	60	48	the	the	DT
cord-288231-vg8bwed9	60	49	emerging	emerge	VBG
cord-288231-vg8bwed9	60	50	virus	virus	NN
cord-288231-vg8bwed9	60	51	.	.	.
cord-288231-vg8bwed9	61	1	By	by	IN
cord-288231-vg8bwed9	61	2	using	use	VBG
cord-288231-vg8bwed9	61	3	genetically	genetically	RB
cord-288231-vg8bwed9	61	4	engineered	engineer	VBN
cord-288231-vg8bwed9	61	5	influenza	influenza	NN
cord-288231-vg8bwed9	61	6	A	a	DT
cord-288231-vg8bwed9	61	7	viruses	virus	NNS
cord-288231-vg8bwed9	61	8	,	,	,
cord-288231-vg8bwed9	61	9	a	a	DT
cord-288231-vg8bwed9	61	10	role	role	NN
cord-288231-vg8bwed9	61	11	for	for	IN
cord-288231-vg8bwed9	61	12	the	the	DT
cord-288231-vg8bwed9	61	13	nonstructural	nonstructural	JJ
cord-288231-vg8bwed9	61	14	NS1	ns1	NN
cord-288231-vg8bwed9	61	15	viral	viral	JJ
cord-288231-vg8bwed9	61	16	protein	protein	NN
cord-288231-vg8bwed9	61	17	in	in	IN
cord-288231-vg8bwed9	61	18	evasion	evasion	NN
cord-288231-vg8bwed9	61	19	of	of	IN
cord-288231-vg8bwed9	61	20	the	the	DT
cord-288231-vg8bwed9	61	21	innate	innate	JJ
cord-288231-vg8bwed9	61	22	host	host	NN
cord-288231-vg8bwed9	61	23	response	response	NN
cord-288231-vg8bwed9	61	24	has	have	VBZ
cord-288231-vg8bwed9	61	25	been	be	VBN
cord-288231-vg8bwed9	61	26	demonstrated	demonstrate	VBN
cord-288231-vg8bwed9	61	27	[	[	-LRB-
cord-288231-vg8bwed9	61	28	14	14	CD
cord-288231-vg8bwed9	61	29	]	]	-RRB-
cord-288231-vg8bwed9	61	30	.	.	.
cord-288231-vg8bwed9	62	1	Interestingly	interestingly	RB
cord-288231-vg8bwed9	62	2	,	,	,
cord-288231-vg8bwed9	62	3	the	the	DT
cord-288231-vg8bwed9	62	4	NS1	ns1	NN
cord-288231-vg8bwed9	62	5	protein	protein	NN
cord-288231-vg8bwed9	62	6	derived	derive	VBN
cord-288231-vg8bwed9	62	7	from	from	IN
cord-288231-vg8bwed9	62	8	the	the	DT
cord-288231-vg8bwed9	62	9	1918	1918	CD
cord-288231-vg8bwed9	62	10	Spanish	Spanish	NNP
cord-288231-vg8bwed9	62	11	H1N1	H1N1	NNP
cord-288231-vg8bwed9	62	12	pandemic	pandemic	NN
cord-288231-vg8bwed9	62	13	influenza	influenza	NN
cord-288231-vg8bwed9	62	14	virus	virus	NN
cord-288231-vg8bwed9	62	15	blocked	block	VBD
cord-288231-vg8bwed9	62	16	expression	expression	NN
cord-288231-vg8bwed9	62	17	of	of	IN
cord-288231-vg8bwed9	62	18	interferon	interferon	NN
cord-288231-vg8bwed9	62	19	-	-	HYPH
cord-288231-vg8bwed9	62	20	regulated	regulate	VBN
cord-288231-vg8bwed9	62	21	genes	gene	NNS
cord-288231-vg8bwed9	62	22	more	more	RBR
cord-288231-vg8bwed9	62	23	efficiently	efficiently	RB
cord-288231-vg8bwed9	62	24	than	than	IN
cord-288231-vg8bwed9	62	25	did	do	VBD
cord-288231-vg8bwed9	62	26	the	the	DT
cord-288231-vg8bwed9	62	27	NS1	ns1	NN
cord-288231-vg8bwed9	62	28	protein	protein	NN
cord-288231-vg8bwed9	62	29	from	from	IN
cord-288231-vg8bwed9	62	30	established	establish	VBN
cord-288231-vg8bwed9	62	31	seasonal	seasonal	JJ
cord-288231-vg8bwed9	62	32	influenza	influenza	NN
cord-288231-vg8bwed9	62	33	viruses	virus	NNS
cord-288231-vg8bwed9	62	34	[	[	-LRB-
cord-288231-vg8bwed9	62	35	14	14	CD
cord-288231-vg8bwed9	62	36	]	]	-RRB-
cord-288231-vg8bwed9	62	37	.	.	.
cord-288231-vg8bwed9	63	1	Other	other	JJ
cord-288231-vg8bwed9	63	2	genomics	genomic	NNS
cord-288231-vg8bwed9	63	3	studies	study	NNS
cord-288231-vg8bwed9	63	4	of	of	IN
cord-288231-vg8bwed9	63	5	genetically	genetically	RB
cord-288231-vg8bwed9	63	6	engineered	engineer	VBN
cord-288231-vg8bwed9	63	7	influenza	influenza	NN
cord-288231-vg8bwed9	63	8	A	a	DT
cord-288231-vg8bwed9	63	9	viruses	virus	NNS
cord-288231-vg8bwed9	63	10	containing	contain	VBG
cord-288231-vg8bwed9	63	11	some	some	DT
cord-288231-vg8bwed9	63	12	or	or	CC
cord-288231-vg8bwed9	63	13	all	all	DT
cord-288231-vg8bwed9	63	14	of	of	IN
cord-288231-vg8bwed9	63	15	the	the	DT
cord-288231-vg8bwed9	63	16	gene	gene	NN
cord-288231-vg8bwed9	63	17	segments	segment	NNS
cord-288231-vg8bwed9	63	18	from	from	IN
cord-288231-vg8bwed9	63	19	either	either	CC
cord-288231-vg8bwed9	63	20	the	the	DT
cord-288231-vg8bwed9	63	21	1918	1918	CD
cord-288231-vg8bwed9	63	22	H1N1	H1N1	NNP
cord-288231-vg8bwed9	63	23	virus	virus	NN
cord-288231-vg8bwed9	63	24	or	or	CC
cord-288231-vg8bwed9	63	25	the	the	DT
cord-288231-vg8bwed9	63	26	highly	highly	RB
cord-288231-vg8bwed9	63	27	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	63	28	avian	avian	JJ
cord-288231-vg8bwed9	63	29	influenza	influenza	NN
cord-288231-vg8bwed9	63	30	A	a	DT
cord-288231-vg8bwed9	63	31	virus	virus	NN
cord-288231-vg8bwed9	63	32	(	(	-LRB-
cord-288231-vg8bwed9	63	33	H5N1	H5N1	NNP
cord-288231-vg8bwed9	63	34	)	)	-RRB-
cord-288231-vg8bwed9	63	35	,	,	,
cord-288231-vg8bwed9	63	36	suggest	suggest	VBP
cord-288231-vg8bwed9	63	37	that	that	IN
cord-288231-vg8bwed9	63	38	these	these	DT
cord-288231-vg8bwed9	63	39	highly	highly	RB
cord-288231-vg8bwed9	63	40	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	63	41	influenza	influenza	NN
cord-288231-vg8bwed9	63	42	viruses	virus	NNS
cord-288231-vg8bwed9	63	43	induce	induce	VBP
cord-288231-vg8bwed9	63	44	severe	severe	JJ
cord-288231-vg8bwed9	63	45	disease	disease	NN
cord-288231-vg8bwed9	63	46	in	in	IN
cord-288231-vg8bwed9	63	47	mice	mouse	NNS
cord-288231-vg8bwed9	63	48	and	and	CC
cord-288231-vg8bwed9	63	49	macaques	macaque	NNS
cord-288231-vg8bwed9	63	50	through	through	IN
cord-288231-vg8bwed9	63	51	aberrant	aberrant	JJ
cord-288231-vg8bwed9	63	52	and	and	CC
cord-288231-vg8bwed9	63	53	persistent	persistent	JJ
cord-288231-vg8bwed9	63	54	activation	activation	NN
cord-288231-vg8bwed9	63	55	of	of	IN
cord-288231-vg8bwed9	63	56	proinflammatory	proinflammatory	JJ
cord-288231-vg8bwed9	63	57	cytokine	cytokine	NN
cord-288231-vg8bwed9	63	58	and	and	CC
cord-288231-vg8bwed9	63	59	chemokine	chemokine	NN
cord-288231-vg8bwed9	63	60	responses	response	NNS
cord-288231-vg8bwed9	63	61	[	[	-LRB-
cord-288231-vg8bwed9	63	62	15	15	CD
cord-288231-vg8bwed9	63	63	]	]	-RRB-
cord-288231-vg8bwed9	63	64	[	[	-LRB-
cord-288231-vg8bwed9	63	65	16	16	CD
cord-288231-vg8bwed9	63	66	]	]	-RRB-
cord-288231-vg8bwed9	63	67	[	[	-LRB-
cord-288231-vg8bwed9	63	68	17	17	CD
cord-288231-vg8bwed9	63	69	]	]	-RRB-
cord-288231-vg8bwed9	63	70	[	[	-LRB-
cord-288231-vg8bwed9	63	71	18	18	CD
cord-288231-vg8bwed9	63	72	]	]	-RRB-
cord-288231-vg8bwed9	63	73	.	.	.
cord-288231-vg8bwed9	64	1	Application	application	NN
cord-288231-vg8bwed9	64	2	of	of	IN
cord-288231-vg8bwed9	64	3	genomics	genomic	NNS
cord-288231-vg8bwed9	64	4	tools	tool	NNS
cord-288231-vg8bwed9	64	5	not	not	RB
cord-288231-vg8bwed9	64	6	only	only	RB
cord-288231-vg8bwed9	64	7	supports	support	VBZ
cord-288231-vg8bwed9	64	8	the	the	DT
cord-288231-vg8bwed9	64	9	elucidation	elucidation	NN
cord-288231-vg8bwed9	64	10	of	of	IN
cord-288231-vg8bwed9	64	11	mechanisms	mechanism	NNS
cord-288231-vg8bwed9	64	12	underlying	underlie	VBG
cord-288231-vg8bwed9	64	13	pathogenesis	pathogenesis	NN
cord-288231-vg8bwed9	64	14	but	but	CC
cord-288231-vg8bwed9	64	15	may	may	MD
cord-288231-vg8bwed9	64	16	also	also	RB
cord-288231-vg8bwed9	64	17	help	help	VB
cord-288231-vg8bwed9	64	18	to	to	TO
cord-288231-vg8bwed9	64	19	identify	identify	VB
cord-288231-vg8bwed9	64	20	leads	lead	NNS
cord-288231-vg8bwed9	64	21	for	for	IN
cord-288231-vg8bwed9	64	22	therapeutic	therapeutic	JJ
cord-288231-vg8bwed9	64	23	intervention	intervention	NN
cord-288231-vg8bwed9	64	24	.	.	.
cord-288231-vg8bwed9	65	1	In	in	IN
cord-288231-vg8bwed9	65	2	ferrets	ferret	NNS
cord-288231-vg8bwed9	65	3	,	,	,
cord-288231-vg8bwed9	65	4	H5N1	H5N1	NNP
cord-288231-vg8bwed9	65	5	infection	infection	NN
cord-288231-vg8bwed9	65	6	induced	induce	VBD
cord-288231-vg8bwed9	65	7	severe	severe	JJ
cord-288231-vg8bwed9	65	8	disease	disease	NN
cord-288231-vg8bwed9	65	9	that	that	WDT
cord-288231-vg8bwed9	65	10	was	be	VBD
cord-288231-vg8bwed9	65	11	associated	associate	VBN
cord-288231-vg8bwed9	65	12	with	with	IN
cord-288231-vg8bwed9	65	13	strong	strong	JJ
cord-288231-vg8bwed9	65	14	expression	expression	NN
cord-288231-vg8bwed9	65	15	of	of	IN
cord-288231-vg8bwed9	65	16	interferon	interferon	NN
cord-288231-vg8bwed9	65	17	response	response	NN
cord-288231-vg8bwed9	65	18	genes	gene	NNS
cord-288231-vg8bwed9	65	19	including	include	VBG
cord-288231-vg8bwed9	65	20	the	the	DT
cord-288231-vg8bwed9	65	21	interferon	interferon	NN
cord-288231-vg8bwed9	65	22	-	-	HYPH
cord-288231-vg8bwed9	65	23	cinduced	cinduce	VBN
cord-288231-vg8bwed9	65	24	cytokine	cytokine	NN
cord-288231-vg8bwed9	65	25	CXCL10	CXCL10	NNP
cord-288231-vg8bwed9	65	26	.	.	.
cord-288231-vg8bwed9	66	1	Treatment	treatment	NN
cord-288231-vg8bwed9	66	2	of	of	IN
cord-288231-vg8bwed9	66	3	H5N1-infected	h5n1-infected	JJ
cord-288231-vg8bwed9	66	4	ferrets	ferret	NNS
cord-288231-vg8bwed9	66	5	with	with	IN
cord-288231-vg8bwed9	66	6	an	an	DT
cord-288231-vg8bwed9	66	7	antagonist	antagonist	NN
cord-288231-vg8bwed9	66	8	of	of	IN
cord-288231-vg8bwed9	66	9	the	the	DT
cord-288231-vg8bwed9	66	10	CXCL10	CXCL10	NNP
cord-288231-vg8bwed9	66	11	receptor	receptor	NN
cord-288231-vg8bwed9	66	12	(	(	-LRB-
cord-288231-vg8bwed9	66	13	CXCR3	cxcr3	NN
cord-288231-vg8bwed9	66	14	)	)	-RRB-
cord-288231-vg8bwed9	66	15	reduced	reduce	VBD
cord-288231-vg8bwed9	66	16	the	the	DT
cord-288231-vg8bwed9	66	17	severity	severity	NN
cord-288231-vg8bwed9	66	18	of	of	IN
cord-288231-vg8bwed9	66	19	the	the	DT
cord-288231-vg8bwed9	66	20	flu	flu	NN
cord-288231-vg8bwed9	66	21	symptoms	symptom	NNS
cord-288231-vg8bwed9	66	22	and	and	CC
cord-288231-vg8bwed9	66	23	the	the	DT
cord-288231-vg8bwed9	66	24	viral	viral	JJ
cord-288231-vg8bwed9	66	25	titers	titer	NNS
cord-288231-vg8bwed9	66	26	compared	compare	VBN
cord-288231-vg8bwed9	66	27	to	to	IN
cord-288231-vg8bwed9	66	28	the	the	DT
cord-288231-vg8bwed9	66	29	controls	control	NNS
cord-288231-vg8bwed9	66	30	[	[	-LRB-
cord-288231-vg8bwed9	66	31	19	19	CD
cord-288231-vg8bwed9	66	32	]	]	-RRB-
cord-288231-vg8bwed9	66	33	,	,	,
cord-288231-vg8bwed9	66	34	clearly	clearly	RB
cord-288231-vg8bwed9	66	35	demonstrating	demonstrate	VBG
cord-288231-vg8bwed9	66	36	the	the	DT
cord-288231-vg8bwed9	66	37	potential	potential	NN
cord-288231-vg8bwed9	66	38	of	of	IN
cord-288231-vg8bwed9	66	39	biological	biological	JJ
cord-288231-vg8bwed9	66	40	response	response	NN
cord-288231-vg8bwed9	66	41	modifiers	modifier	NNS
cord-288231-vg8bwed9	66	42	for	for	IN
cord-288231-vg8bwed9	66	43	the	the	DT
cord-288231-vg8bwed9	66	44	clinical	clinical	JJ
cord-288231-vg8bwed9	66	45	management	management	NN
cord-288231-vg8bwed9	66	46	of	of	IN
cord-288231-vg8bwed9	66	47	viral	viral	JJ
cord-288231-vg8bwed9	66	48	infections	infection	NNS
cord-288231-vg8bwed9	66	49	.	.	.
cord-288231-vg8bwed9	67	1	The	the	DT
cord-288231-vg8bwed9	67	2	host	host	NN
cord-288231-vg8bwed9	67	3	evasion	evasion	NN
cord-288231-vg8bwed9	67	4	and	and	CC
cord-288231-vg8bwed9	67	5	evolution	evolution	NN
cord-288231-vg8bwed9	67	6	of	of	IN
cord-288231-vg8bwed9	67	7	influenza	influenza	NN
cord-288231-vg8bwed9	67	8	virus	virus	NN
cord-288231-vg8bwed9	67	9	is	be	VBZ
cord-288231-vg8bwed9	67	10	further	further	RB
cord-288231-vg8bwed9	67	11	discussed	discuss	VBN
cord-288231-vg8bwed9	67	12	in	in	IN
cord-288231-vg8bwed9	67	13	[	[	-LRB-
cord-288231-vg8bwed9	67	14	20	20	CD
cord-288231-vg8bwed9	67	15	]	]	-RRB-
cord-288231-vg8bwed9	67	16	.	.	.
cord-288231-vg8bwed9	68	1	Coronaviruses	Coronaviruses	NNP
cord-288231-vg8bwed9	68	2	(	(	-LRB-
cord-288231-vg8bwed9	68	3	CoVs	CoVs	NNP
cord-288231-vg8bwed9	68	4	)	)	-RRB-
cord-288231-vg8bwed9	68	5	primarily	primarily	RB
cord-288231-vg8bwed9	68	6	infect	infect	VBP
cord-288231-vg8bwed9	68	7	the	the	DT
cord-288231-vg8bwed9	68	8	upper	upper	JJ
cord-288231-vg8bwed9	68	9	respiratory	respiratory	JJ
cord-288231-vg8bwed9	68	10	and	and	CC
cord-288231-vg8bwed9	68	11	gastrointestinal	gastrointestinal	JJ
cord-288231-vg8bwed9	68	12	tract	tract	NN
cord-288231-vg8bwed9	68	13	of	of	IN
cord-288231-vg8bwed9	68	14	mammals	mammal	NNS
cord-288231-vg8bwed9	68	15	and	and	CC
cord-288231-vg8bwed9	68	16	birds	bird	NNS
cord-288231-vg8bwed9	68	17	.	.	.
cord-288231-vg8bwed9	69	1	Five	five	CD
cord-288231-vg8bwed9	69	2	different	different	JJ
cord-288231-vg8bwed9	69	3	currently	currently	RB
cord-288231-vg8bwed9	69	4	known	know	VBN
cord-288231-vg8bwed9	69	5	CoVs	covs	NN
cord-288231-vg8bwed9	69	6	infect	infect	VBP
cord-288231-vg8bwed9	69	7	humans	human	NNS
cord-288231-vg8bwed9	69	8	and	and	CC
cord-288231-vg8bwed9	69	9	are	be	VBP
cord-288231-vg8bwed9	69	10	believed	believe	VBN
cord-288231-vg8bwed9	69	11	to	to	TO
cord-288231-vg8bwed9	69	12	cause	cause	VB
cord-288231-vg8bwed9	69	13	a	a	DT
cord-288231-vg8bwed9	69	14	significant	significant	JJ
cord-288231-vg8bwed9	69	15	percentage	percentage	NN
cord-288231-vg8bwed9	69	16	of	of	IN
cord-288231-vg8bwed9	69	17	all	all	DT
cord-288231-vg8bwed9	69	18	common	common	JJ
cord-288231-vg8bwed9	69	19	colds	cold	NNS
cord-288231-vg8bwed9	69	20	in	in	IN
cord-288231-vg8bwed9	69	21	human	human	JJ
cord-288231-vg8bwed9	69	22	adults	adult	NNS
cord-288231-vg8bwed9	69	23	.	.	.
cord-288231-vg8bwed9	70	1	Surprisingly	surprisingly	RB
cord-288231-vg8bwed9	70	2	,	,	,
cord-288231-vg8bwed9	70	3	recent	recent	JJ
cord-288231-vg8bwed9	70	4	studies	study	NNS
cord-288231-vg8bwed9	70	5	revealed	reveal	VBD
cord-288231-vg8bwed9	70	6	that	that	IN
cord-288231-vg8bwed9	70	7	approximately	approximately	RB
cord-288231-vg8bwed9	70	8	6	6	CD
cord-288231-vg8bwed9	70	9	%	%	NN
cord-288231-vg8bwed9	70	10	of	of	IN
cord-288231-vg8bwed9	70	11	bats	bat	NNS
cord-288231-vg8bwed9	70	12	sampled	sample	VBN
cord-288231-vg8bwed9	70	13	in	in	IN
cord-288231-vg8bwed9	70	14	China	China	NNP
cord-288231-vg8bwed9	70	15	were	be	VBD
cord-288231-vg8bwed9	70	16	positive	positive	JJ
cord-288231-vg8bwed9	70	17	for	for	IN
cord-288231-vg8bwed9	70	18	CoVs	CoVs	NNP
cord-288231-vg8bwed9	70	19	[	[	-LRB-
cord-288231-vg8bwed9	70	20	21	21	CD
cord-288231-vg8bwed9	70	21	]	]	-RRB-
cord-288231-vg8bwed9	70	22	.	.	.
cord-288231-vg8bwed9	71	1	Subsequent	subsequent	JJ
cord-288231-vg8bwed9	71	2	phylogenetic	phylogenetic	JJ
cord-288231-vg8bwed9	71	3	studies	study	NNS
cord-288231-vg8bwed9	71	4	revealed	reveal	VBD
cord-288231-vg8bwed9	71	5	that	that	IN
cord-288231-vg8bwed9	71	6	bat	bat	NN
cord-288231-vg8bwed9	71	7	CoVs	CoVs	NNP
cord-288231-vg8bwed9	71	8	that	that	WDT
cord-288231-vg8bwed9	71	9	resembled	resemble	VBD
cord-288231-vg8bwed9	71	10	human	human	JJ
cord-288231-vg8bwed9	71	11	SARS	SARS	NNP
cord-288231-vg8bwed9	71	12	-	-	HYPH
cord-288231-vg8bwed9	71	13	CoV	CoV	NNP
cord-288231-vg8bwed9	71	14	clustered	cluster	VBN
cord-288231-vg8bwed9	71	15	in	in	IN
cord-288231-vg8bwed9	71	16	a	a	DT
cord-288231-vg8bwed9	71	17	putative	putative	JJ
cord-288231-vg8bwed9	71	18	group	group	NN
cord-288231-vg8bwed9	71	19	comprising	comprise	VBG
cord-288231-vg8bwed9	71	20	one	one	CD
cord-288231-vg8bwed9	71	21	subgroup	subgroup	NN
cord-288231-vg8bwed9	71	22	of	of	IN
cord-288231-vg8bwed9	71	23	bat	bat	NN
cord-288231-vg8bwed9	71	24	CoVs	CoVs	NNP
cord-288231-vg8bwed9	71	25	and	and	CC
cord-288231-vg8bwed9	71	26	another	another	DT
cord-288231-vg8bwed9	71	27	of	of	IN
cord-288231-vg8bwed9	71	28	SARS	SARS	NNP
cord-288231-vg8bwed9	71	29	-	-	HYPH
cord-288231-vg8bwed9	71	30	CoVs	CoVs	NNP
cord-288231-vg8bwed9	71	31	from	from	IN
cord-288231-vg8bwed9	71	32	humans	human	NNS
cord-288231-vg8bwed9	71	33	and	and	CC
cord-288231-vg8bwed9	71	34	other	other	JJ
cord-288231-vg8bwed9	71	35	mammalian	mammalian	JJ
cord-288231-vg8bwed9	71	36	hosts	host	NNS
cord-288231-vg8bwed9	71	37	.	.	.
cord-288231-vg8bwed9	72	1	According	accord	VBG
cord-288231-vg8bwed9	72	2	to	to	IN
cord-288231-vg8bwed9	72	3	the	the	DT
cord-288231-vg8bwed9	72	4	current	current	JJ
cord-288231-vg8bwed9	72	5	hypothesis	hypothesis	NN
cord-288231-vg8bwed9	72	6	SARS	SARS	NNP
cord-288231-vg8bwed9	72	7	-	-	HYPH
cord-288231-vg8bwed9	72	8	CoV	CoV	NNP
cord-288231-vg8bwed9	72	9	has	have	VBZ
cord-288231-vg8bwed9	72	10	arisen	arise	VBN
cord-288231-vg8bwed9	72	11	by	by	IN
cord-288231-vg8bwed9	72	12	recombination	recombination	NN
cord-288231-vg8bwed9	72	13	between	between	IN
cord-288231-vg8bwed9	72	14	two	two	CD
cord-288231-vg8bwed9	72	15	bat	bat	NN
cord-288231-vg8bwed9	72	16	viruses	virus	NNS
cord-288231-vg8bwed9	72	17	.	.	.
cord-288231-vg8bwed9	73	1	Phylogenetic	phylogenetic	JJ
cord-288231-vg8bwed9	73	2	analysis	analysis	NN
cord-288231-vg8bwed9	73	3	of	of	IN
cord-288231-vg8bwed9	73	4	SARS	SARS	NNP
cord-288231-vg8bwed9	73	5	-	-	HYPH
cord-288231-vg8bwed9	73	6	CoV	CoV	NNP
cord-288231-vg8bwed9	73	7	isolates	isolate	NNS
cord-288231-vg8bwed9	73	8	from	from	IN
cord-288231-vg8bwed9	73	9	animals	animal	NNS
cord-288231-vg8bwed9	73	10	indicate	indicate	VBP
cord-288231-vg8bwed9	73	11	that	that	IN
cord-288231-vg8bwed9	73	12	the	the	DT
cord-288231-vg8bwed9	73	13	resulting	result	VBG
cord-288231-vg8bwed9	73	14	bat	bat	NN
cord-288231-vg8bwed9	73	15	virus	virus	NN
cord-288231-vg8bwed9	73	16	was	be	VBD
cord-288231-vg8bwed9	73	17	transmitted	transmit	VBN
cord-288231-vg8bwed9	73	18	first	first	RB
cord-288231-vg8bwed9	73	19	to	to	TO
cord-288231-vg8bwed9	73	20	palm	palm	NN
cord-288231-vg8bwed9	73	21	civets	civet	NNS
cord-288231-vg8bwed9	73	22	(	(	-LRB-
cord-288231-vg8bwed9	73	23	Paguma	Paguma	NNP
cord-288231-vg8bwed9	73	24	larvata	larvata	NNP
cord-288231-vg8bwed9	73	25	)	)	-RRB-
cord-288231-vg8bwed9	73	26	,	,	,
cord-288231-vg8bwed9	73	27	a	a	DT
cord-288231-vg8bwed9	73	28	wild	wild	JJ
cord-288231-vg8bwed9	73	29	cat	cat	NN
cord-288231-vg8bwed9	73	30	-	-	HYPH
cord-288231-vg8bwed9	73	31	like	like	JJ
cord-288231-vg8bwed9	73	32	animal	animal	NN
cord-288231-vg8bwed9	73	33	hunted	hunt	VBN
cord-288231-vg8bwed9	73	34	for	for	IN
cord-288231-vg8bwed9	73	35	its	-PRON-	PRP$
cord-288231-vg8bwed9	73	36	meat	meat	NN
cord-288231-vg8bwed9	73	37	,	,	,
cord-288231-vg8bwed9	73	38	and	and	CC
cord-288231-vg8bwed9	73	39	subsequently	subsequently	RB
cord-288231-vg8bwed9	73	40	to	to	IN
cord-288231-vg8bwed9	73	41	humans	human	NNS
cord-288231-vg8bwed9	73	42	at	at	IN
cord-288231-vg8bwed9	73	43	live	live	JJ
cord-288231-vg8bwed9	73	44	animal	animal	NN
cord-288231-vg8bwed9	73	45	markets	market	NNS
cord-288231-vg8bwed9	73	46	in	in	IN
cord-288231-vg8bwed9	73	47	southern	southern	JJ
cord-288231-vg8bwed9	73	48	China	China	NNP
cord-288231-vg8bwed9	73	49	[	[	-LRB-
cord-288231-vg8bwed9	73	50	22	22	CD
cord-288231-vg8bwed9	73	51	]	]	-RRB-
cord-288231-vg8bwed9	73	52	.	.	.
cord-288231-vg8bwed9	74	1	Genome	genome	NN
cord-288231-vg8bwed9	74	2	analyses	analysis	NNS
cord-288231-vg8bwed9	74	3	have	have	VBP
cord-288231-vg8bwed9	74	4	provided	provide	VBN
cord-288231-vg8bwed9	74	5	evidence	evidence	NN
cord-288231-vg8bwed9	74	6	that	that	IN
cord-288231-vg8bwed9	74	7	genetic	genetic	JJ
cord-288231-vg8bwed9	74	8	variation	variation	NN
cord-288231-vg8bwed9	74	9	in	in	IN
cord-288231-vg8bwed9	74	10	the	the	DT
cord-288231-vg8bwed9	74	11	spike	spike	NN
cord-288231-vg8bwed9	74	12	gene	gene	NN
cord-288231-vg8bwed9	74	13	of	of	IN
cord-288231-vg8bwed9	74	14	these	these	DT
cord-288231-vg8bwed9	74	15	viruses	virus	NNS
cord-288231-vg8bwed9	74	16	from	from	IN
cord-288231-vg8bwed9	74	17	civets	civet	NNS
cord-288231-vg8bwed9	74	18	is	be	VBZ
cord-288231-vg8bwed9	74	19	associated	associate	VBN
cord-288231-vg8bwed9	74	20	with	with	IN
cord-288231-vg8bwed9	74	21	increased	increase	VBN
cord-288231-vg8bwed9	74	22	transmission	transmission	NN
cord-288231-vg8bwed9	74	23	of	of	IN
cord-288231-vg8bwed9	74	24	the	the	DT
cord-288231-vg8bwed9	74	25	virus	virus	NN
cord-288231-vg8bwed9	74	26	[	[	-LRB-
cord-288231-vg8bwed9	74	27	21	21	CD
cord-288231-vg8bwed9	74	28	]	]	-RRB-
cord-288231-vg8bwed9	74	29	.	.	.
cord-288231-vg8bwed9	75	1	In	in	IN
cord-288231-vg8bwed9	75	2	addition	addition	NN
cord-288231-vg8bwed9	75	3	,	,	,
cord-288231-vg8bwed9	75	4	species	specie	NNS
cord-288231-vg8bwed9	75	5	-	-	HYPH
cord-288231-vg8bwed9	75	6	tospecies	tospecies	NN
cord-288231-vg8bwed9	75	7	variation	variation	NN
cord-288231-vg8bwed9	75	8	in	in	IN
cord-288231-vg8bwed9	75	9	the	the	DT
cord-288231-vg8bwed9	75	10	sequence	sequence	NN
cord-288231-vg8bwed9	75	11	of	of	IN
cord-288231-vg8bwed9	75	12	the	the	DT
cord-288231-vg8bwed9	75	13	gene	gene	NN
cord-288231-vg8bwed9	75	14	angiotensin	angiotensin	NN
cord-288231-vg8bwed9	75	15	-	-	HYPH
cord-288231-vg8bwed9	75	16	converting	convert	VBG
cord-288231-vg8bwed9	75	17	enzyme	enzyme	NN
cord-288231-vg8bwed9	75	18	2	2	CD
cord-288231-vg8bwed9	75	19	(	(	-LRB-
cord-288231-vg8bwed9	75	20	ACE2	ACE2	NNP
cord-288231-vg8bwed9	75	21	)	)	-RRB-
cord-288231-vg8bwed9	75	22	,	,	,
cord-288231-vg8bwed9	75	23	which	which	WDT
cord-288231-vg8bwed9	75	24	encodes	encode	VBZ
cord-288231-vg8bwed9	75	25	the	the	DT
cord-288231-vg8bwed9	75	26	SARS	SARS	NNP
cord-288231-vg8bwed9	75	27	-	-	HYPH
cord-288231-vg8bwed9	75	28	CoV	CoV	NNP
cord-288231-vg8bwed9	75	29	receptor	receptor	NN
cord-288231-vg8bwed9	75	30	,	,	,
cord-288231-vg8bwed9	75	31	also	also	RB
cord-288231-vg8bwed9	75	32	affects	affect	VBZ
cord-288231-vg8bwed9	75	33	the	the	DT
cord-288231-vg8bwed9	75	34	efficiency	efficiency	NN
cord-288231-vg8bwed9	75	35	by	by	IN
cord-288231-vg8bwed9	75	36	which	which	WDT
cord-288231-vg8bwed9	75	37	the	the	DT
cord-288231-vg8bwed9	75	38	virus	virus	NN
cord-288231-vg8bwed9	75	39	can	can	MD
cord-288231-vg8bwed9	75	40	enter	enter	VB
cord-288231-vg8bwed9	75	41	cells	cell	NNS
cord-288231-vg8bwed9	75	42	[	[	-LRB-
cord-288231-vg8bwed9	75	43	23	23	CD
cord-288231-vg8bwed9	75	44	]	]	-RRB-
cord-288231-vg8bwed9	75	45	.	.	.
cord-288231-vg8bwed9	76	1	By	by	IN
cord-288231-vg8bwed9	76	2	a	a	DT
cord-288231-vg8bwed9	76	3	combination	combination	NN
cord-288231-vg8bwed9	76	4	of	of	IN
cord-288231-vg8bwed9	76	5	phylogenetic	phylogenetic	NN
cord-288231-vg8bwed9	76	6	and	and	CC
cord-288231-vg8bwed9	76	7	bioinformatics	bioinformatics	NN
cord-288231-vg8bwed9	76	8	analyses	analysis	NNS
cord-288231-vg8bwed9	76	9	,	,	,
cord-288231-vg8bwed9	76	10	chimeric	chimeric	JJ
cord-288231-vg8bwed9	76	11	gene	gene	NN
cord-288231-vg8bwed9	76	12	design	design	NN
cord-288231-vg8bwed9	76	13	,	,	,
cord-288231-vg8bwed9	76	14	and	and	CC
cord-288231-vg8bwed9	76	15	reverse	reverse	VB
cord-288231-vg8bwed9	76	16	genetics	genetics	NN
cord-288231-vg8bwed9	76	17	-	-	HYPH
cord-288231-vg8bwed9	76	18	aided	aid	VBN
cord-288231-vg8bwed9	76	19	generation	generation	NN
cord-288231-vg8bwed9	76	20	of	of	IN
cord-288231-vg8bwed9	76	21	viruses	virus	NNS
cord-288231-vg8bwed9	76	22	that	that	WDT
cord-288231-vg8bwed9	76	23	encode	encode	VBP
cord-288231-vg8bwed9	76	24	spike	spike	NN
cord-288231-vg8bwed9	76	25	proteins	protein	NNS
cord-288231-vg8bwed9	76	26	of	of	IN
cord-288231-vg8bwed9	76	27	diverse	diverse	JJ
cord-288231-vg8bwed9	76	28	isolates	isolate	NNS
cord-288231-vg8bwed9	76	29	,	,	,
cord-288231-vg8bwed9	76	30	researchers	researcher	NNS
cord-288231-vg8bwed9	76	31	have	have	VBP
cord-288231-vg8bwed9	76	32	reconstructed	reconstruct	VBN
cord-288231-vg8bwed9	76	33	the	the	DT
cord-288231-vg8bwed9	76	34	events	event	NNS
cord-288231-vg8bwed9	76	35	that	that	WDT
cord-288231-vg8bwed9	76	36	led	lead	VBD
cord-288231-vg8bwed9	76	37	to	to	IN
cord-288231-vg8bwed9	76	38	the	the	DT
cord-288231-vg8bwed9	76	39	emergence	emergence	NN
cord-288231-vg8bwed9	76	40	of	of	IN
cord-288231-vg8bwed9	76	41	a	a	DT
cord-288231-vg8bwed9	76	42	virus	virus	NN
cord-288231-vg8bwed9	76	43	able	able	JJ
cord-288231-vg8bwed9	76	44	to	to	TO
cord-288231-vg8bwed9	76	45	spread	spread	VB
cord-288231-vg8bwed9	76	46	efficiently	efficiently	RB
cord-288231-vg8bwed9	76	47	in	in	IN
cord-288231-vg8bwed9	76	48	humans	human	NNS
cord-288231-vg8bwed9	76	49	[	[	-LRB-
cord-288231-vg8bwed9	76	50	24	24	CD
cord-288231-vg8bwed9	76	51	]	]	-RRB-
cord-288231-vg8bwed9	76	52	.	.	.
cord-288231-vg8bwed9	77	1	Structural	structural	JJ
cord-288231-vg8bwed9	77	2	modeling	modeling	NN
cord-288231-vg8bwed9	77	3	predicted	predict	VBD
cord-288231-vg8bwed9	77	4	that	that	IN
cord-288231-vg8bwed9	77	5	the	the	DT
cord-288231-vg8bwed9	77	6	SARS	SARS	NNP
cord-288231-vg8bwed9	77	7	-	-	HYPH
cord-288231-vg8bwed9	77	8	CoV	CoV	NNP
cord-288231-vg8bwed9	77	9	that	that	WDT
cord-288231-vg8bwed9	77	10	caused	cause	VBD
cord-288231-vg8bwed9	77	11	the	the	DT
cord-288231-vg8bwed9	77	12	epidemic	epidemic	NN
cord-288231-vg8bwed9	77	13	had	have	VBD
cord-288231-vg8bwed9	77	14	an	an	DT
cord-288231-vg8bwed9	77	15	increased	increase	VBN
cord-288231-vg8bwed9	77	16	affinity	affinity	NN
cord-288231-vg8bwed9	77	17	for	for	IN
cord-288231-vg8bwed9	77	18	both	both	DT
cord-288231-vg8bwed9	77	19	civet	civet	NN
cord-288231-vg8bwed9	77	20	and	and	CC
cord-288231-vg8bwed9	77	21	human	human	JJ
cord-288231-vg8bwed9	77	22	ACE2	ACE2	NNP
cord-288231-vg8bwed9	77	23	receptors	receptor	NNS
cord-288231-vg8bwed9	77	24	due	due	JJ
cord-288231-vg8bwed9	77	25	to	to	IN
cord-288231-vg8bwed9	77	26	adaptation	adaptation	NN
cord-288231-vg8bwed9	77	27	(	(	-LRB-
cord-288231-vg8bwed9	77	28	Figure	figure	NN
cord-288231-vg8bwed9	77	29	2	2	CD
cord-288231-vg8bwed9	77	30	)	)	-RRB-
cord-288231-vg8bwed9	77	31	.	.	.
cord-288231-vg8bwed9	78	1	Subsequent	subsequent	JJ
cord-288231-vg8bwed9	78	2	functional	functional	JJ
cord-288231-vg8bwed9	78	3	genomics	genomic	NNS
cord-288231-vg8bwed9	78	4	studies	study	NNS
cord-288231-vg8bwed9	78	5	of	of	IN
cord-288231-vg8bwed9	78	6	these	these	DT
cord-288231-vg8bwed9	78	7	viruses	virus	NNS
cord-288231-vg8bwed9	78	8	in	in	IN
cord-288231-vg8bwed9	78	9	diverse	diverse	JJ
cord-288231-vg8bwed9	78	10	species	specie	NNS
cord-288231-vg8bwed9	78	11	provided	provide	VBN
cord-288231-vg8bwed9	78	12	further	further	JJ
cord-288231-vg8bwed9	78	13	insight	insight	NN
cord-288231-vg8bwed9	78	14	into	into	IN
cord-288231-vg8bwed9	78	15	the	the	DT
cord-288231-vg8bwed9	78	16	role	role	NN
cord-288231-vg8bwed9	78	17	of	of	IN
cord-288231-vg8bwed9	78	18	specific	specific	JJ
cord-288231-vg8bwed9	78	19	host	host	NN
cord-288231-vg8bwed9	78	20	genes	gene	NNS
cord-288231-vg8bwed9	78	21	involved	involve	VBN
cord-288231-vg8bwed9	78	22	in	in	IN
cord-288231-vg8bwed9	78	23	the	the	DT
cord-288231-vg8bwed9	78	24	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	78	25	response	response	NN
cord-288231-vg8bwed9	78	26	[	[	-LRB-
cord-288231-vg8bwed9	78	27	25	25	CD
cord-288231-vg8bwed9	78	28	,	,	,
cord-288231-vg8bwed9	78	29	26	26	CD
cord-288231-vg8bwed9	78	30	]	]	-RRB-
cord-288231-vg8bwed9	78	31	.	.	.
cord-288231-vg8bwed9	79	1	The	the	DT
cord-288231-vg8bwed9	79	2	pathological	pathological	JJ
cord-288231-vg8bwed9	79	3	changes	change	NNS
cord-288231-vg8bwed9	79	4	observed	observe	VBN
cord-288231-vg8bwed9	79	5	in	in	IN
cord-288231-vg8bwed9	79	6	the	the	DT
cord-288231-vg8bwed9	79	7	lungs	lung	NNS
cord-288231-vg8bwed9	79	8	are	be	VBP
cord-288231-vg8bwed9	79	9	initiated	initiate	VBN
cord-288231-vg8bwed9	79	10	by	by	IN
cord-288231-vg8bwed9	79	11	a	a	DT
cord-288231-vg8bwed9	79	12	disproportionate	disproportionate	JJ
cord-288231-vg8bwed9	79	13	innate	innate	JJ
cord-288231-vg8bwed9	79	14	immune	immune	JJ
cord-288231-vg8bwed9	79	15	response	response	NN
cord-288231-vg8bwed9	79	16	,	,	,
cord-288231-vg8bwed9	79	17	illustrated	illustrate	VBN
cord-288231-vg8bwed9	79	18	by	by	IN
cord-288231-vg8bwed9	79	19	elevated	elevated	JJ
cord-288231-vg8bwed9	79	20	levels	level	NNS
cord-288231-vg8bwed9	79	21	of	of	IN
cord-288231-vg8bwed9	79	22	inflammatory	inflammatory	JJ
cord-288231-vg8bwed9	79	23	cytokines	cytokine	NNS
cord-288231-vg8bwed9	79	24	and	and	CC
cord-288231-vg8bwed9	79	25	chemokines	chemokine	NNS
cord-288231-vg8bwed9	79	26	,	,	,
cord-288231-vg8bwed9	79	27	such	such	JJ
cord-288231-vg8bwed9	79	28	The	the	DT
cord-288231-vg8bwed9	79	29	hemagglutinin	hemagglutinin	NN
cord-288231-vg8bwed9	79	30	of	of	IN
cord-288231-vg8bwed9	79	31	avian	avian	JJ
cord-288231-vg8bwed9	79	32	influenza	influenza	NN
cord-288231-vg8bwed9	79	33	A	a	DT
cord-288231-vg8bwed9	79	34	viruses	virus	NNS
cord-288231-vg8bwed9	79	35	(	(	-LRB-
cord-288231-vg8bwed9	79	36	blue	blue	JJ
cord-288231-vg8bwed9	79	37	)	)	-RRB-
cord-288231-vg8bwed9	79	38	preferentially	preferentially	RB
cord-288231-vg8bwed9	79	39	bind	bind	VBP
cord-288231-vg8bwed9	79	40	to	to	IN
cord-288231-vg8bwed9	79	41	oligosaccharides	oligosaccharide	NNS
cord-288231-vg8bwed9	79	42	that	that	WDT
cord-288231-vg8bwed9	79	43	terminate	terminate	VBP
cord-288231-vg8bwed9	79	44	in	in	IN
cord-288231-vg8bwed9	79	45	sialic	sialic	JJ
cord-288231-vg8bwed9	79	46	acid	acid	NN
cord-288231-vg8bwed9	79	47	-	-	:
cord-288231-vg8bwed9	79	48	a-2,3-Gal	a-2,3-gal	NN
cord-288231-vg8bwed9	79	49	(	(	-LRB-
cord-288231-vg8bwed9	79	50	red	red	NNP
cord-288231-vg8bwed9	79	51	)	)	-RRB-
cord-288231-vg8bwed9	79	52	,	,	,
cord-288231-vg8bwed9	79	53	whereas	whereas	IN
cord-288231-vg8bwed9	79	54	the	the	DT
cord-288231-vg8bwed9	79	55	hemagglutinin	hemagglutinin	NN
cord-288231-vg8bwed9	79	56	on	on	IN
cord-288231-vg8bwed9	79	57	human	human	JJ
cord-288231-vg8bwed9	79	58	influenza	influenza	NN
cord-288231-vg8bwed9	79	59	A	a	DT
cord-288231-vg8bwed9	79	60	viruses	virus	NNS
cord-288231-vg8bwed9	79	61	(	(	-LRB-
cord-288231-vg8bwed9	79	62	green	green	JJ
cord-288231-vg8bwed9	79	63	)	)	-RRB-
cord-288231-vg8bwed9	79	64	prefer	prefer	VBP
cord-288231-vg8bwed9	79	65	oligosaccharides	oligosaccharide	NNS
cord-288231-vg8bwed9	79	66	that	that	WDT
cord-288231-vg8bwed9	79	67	terminate	terminate	VBP
cord-288231-vg8bwed9	79	68	in	in	IN
cord-288231-vg8bwed9	79	69	sialic	sialic	JJ
cord-288231-vg8bwed9	79	70	acid	acid	NN
cord-288231-vg8bwed9	79	71	-	-	:
cord-288231-vg8bwed9	79	72	a-2,6-Gal	a-2,6-gal	DT
cord-288231-vg8bwed9	79	73	(	(	-LRB-
cord-288231-vg8bwed9	79	74	orange	orange	NNP
cord-288231-vg8bwed9	79	75	)	)	-RRB-
cord-288231-vg8bwed9	79	76	.	.	.
cord-288231-vg8bwed9	80	1	Fatal	fatal	JJ
cord-288231-vg8bwed9	80	2	viral	viral	JJ
cord-288231-vg8bwed9	80	3	pneumonia	pneumonia	NN
cord-288231-vg8bwed9	80	4	in	in	IN
cord-288231-vg8bwed9	80	5	humans	human	NNS
cord-288231-vg8bwed9	80	6	infected	infect	VBN
cord-288231-vg8bwed9	80	7	with	with	IN
cord-288231-vg8bwed9	80	8	the	the	DT
cord-288231-vg8bwed9	80	9	H5N1	H5N1	NNP
cord-288231-vg8bwed9	80	10	subtype	subtype	NN
cord-288231-vg8bwed9	80	11	of	of	IN
cord-288231-vg8bwed9	80	12	avian	avian	JJ
cord-288231-vg8bwed9	80	13	influenza	influenza	NN
cord-288231-vg8bwed9	80	14	A	a	DT
cord-288231-vg8bwed9	80	15	viruses	virus	NNS
cord-288231-vg8bwed9	80	16	is	be	VBZ
cord-288231-vg8bwed9	80	17	likely	likely	JJ
cord-288231-vg8bwed9	80	18	due	due	IN
cord-288231-vg8bwed9	80	19	to	to	IN
cord-288231-vg8bwed9	80	20	the	the	DT
cord-288231-vg8bwed9	80	21	ability	ability	NN
cord-288231-vg8bwed9	80	22	of	of	IN
cord-288231-vg8bwed9	80	23	these	these	DT
cord-288231-vg8bwed9	80	24	viruses	virus	NNS
cord-288231-vg8bwed9	80	25	to	to	TO
cord-288231-vg8bwed9	80	26	attach	attach	VB
cord-288231-vg8bwed9	80	27	to	to	TO
cord-288231-vg8bwed9	80	28	and	and	CC
cord-288231-vg8bwed9	80	29	replicate	replicate	VB
cord-288231-vg8bwed9	80	30	in	in	IN
cord-288231-vg8bwed9	80	31	the	the	DT
cord-288231-vg8bwed9	80	32	lower	low	JJR
cord-288231-vg8bwed9	80	33	respiratory	respiratory	JJ
cord-288231-vg8bwed9	80	34	tract	tract	NN
cord-288231-vg8bwed9	80	35	cells	cell	NNS
cord-288231-vg8bwed9	80	36	,	,	,
cord-288231-vg8bwed9	80	37	which	which	WDT
cord-288231-vg8bwed9	80	38	have	have	VBP
cord-288231-vg8bwed9	80	39	sialic	sialic	JJ
cord-288231-vg8bwed9	80	40	acid	acid	NN
cord-288231-vg8bwed9	80	41	-	-	:
cord-288231-vg8bwed9	80	42	a-2,3-Gal	a-2,3-gal	NN
cord-288231-vg8bwed9	80	43	terminated	terminate	VBN
cord-288231-vg8bwed9	80	44	saccharides	saccharide	NNS
cord-288231-vg8bwed9	80	45	.	.	.
cord-288231-vg8bwed9	81	1	The	the	DT
cord-288231-vg8bwed9	81	2	horizontal	horizontal	JJ
cord-288231-vg8bwed9	81	3	arrows	arrow	NNS
cord-288231-vg8bwed9	81	4	indicate	indicate	VBP
cord-288231-vg8bwed9	81	5	interspecies	interspecies	JJ
cord-288231-vg8bwed9	81	6	transmission	transmission	NN
cord-288231-vg8bwed9	81	7	,	,	,
cord-288231-vg8bwed9	81	8	including	include	VBG
cord-288231-vg8bwed9	81	9	the	the	DT
cord-288231-vg8bwed9	81	10	transmission	transmission	NN
cord-288231-vg8bwed9	81	11	from	from	IN
cord-288231-vg8bwed9	81	12	an	an	DT
cord-288231-vg8bwed9	81	13	avian	avian	JJ
cord-288231-vg8bwed9	81	14	or	or	CC
cord-288231-vg8bwed9	81	15	porcine	porcine	JJ
cord-288231-vg8bwed9	81	16	reservoir	reservoir	NN
cord-288231-vg8bwed9	81	17	into	into	IN
cord-288231-vg8bwed9	81	18	the	the	DT
cord-288231-vg8bwed9	81	19	human	human	JJ
cord-288231-vg8bwed9	81	20	species	specie	NNS
cord-288231-vg8bwed9	81	21	.	.	.
cord-288231-vg8bwed9	82	1	Image	image	NN
cord-288231-vg8bwed9	82	2	credit	credit	NN
cord-288231-vg8bwed9	82	3	:	:	:
cord-288231-vg8bwed9	82	4	Bart	Bart	NNP
cord-288231-vg8bwed9	82	5	as	as	IN
cord-288231-vg8bwed9	82	6	CXCL10	CXCL10	NNP
cord-288231-vg8bwed9	82	7	(	(	-LRB-
cord-288231-vg8bwed9	83	1	IP-10	IP-10	NNP
cord-288231-vg8bwed9	83	2	)	)	-RRB-
cord-288231-vg8bwed9	83	3	,	,	,
cord-288231-vg8bwed9	83	4	CCL2	CCL2	NNP
cord-288231-vg8bwed9	83	5	(	(	-LRB-
cord-288231-vg8bwed9	83	6	MCP-1	MCP-1	NNP
cord-288231-vg8bwed9	83	7	)	)	-RRB-
cord-288231-vg8bwed9	83	8	,	,	,
cord-288231-vg8bwed9	83	9	interleukin	interleukin	FW
cord-288231-vg8bwed9	83	10	(	(	-LRB-
cord-288231-vg8bwed9	83	11	IL)-6	IL)-6	NNP
cord-288231-vg8bwed9	83	12	,	,	,
cord-288231-vg8bwed9	83	13	IL-8	IL-8	NNP
cord-288231-vg8bwed9	83	14	,	,	,
cord-288231-vg8bwed9	83	15	IL-12	IL-12	NNP
cord-288231-vg8bwed9	83	16	,	,	,
cord-288231-vg8bwed9	83	17	IL-1b	IL-1b	NNS
cord-288231-vg8bwed9	83	18	,	,	,
cord-288231-vg8bwed9	83	19	and	and	CC
cord-288231-vg8bwed9	83	20	interferon	interferon	NN
cord-288231-vg8bwed9	83	21	-	-	HYPH
cord-288231-vg8bwed9	83	22	c	c	NN
cord-288231-vg8bwed9	83	23	[	[	-LRB-
cord-288231-vg8bwed9	83	24	27	27	CD
cord-288231-vg8bwed9	83	25	]	]	-RRB-
cord-288231-vg8bwed9	83	26	.	.	.
cord-288231-vg8bwed9	84	1	These	these	DT
cord-288231-vg8bwed9	84	2	clinical	clinical	JJ
cord-288231-vg8bwed9	84	3	data	datum	NNS
cord-288231-vg8bwed9	84	4	were	be	VBD
cord-288231-vg8bwed9	84	5	confirmed	confirm	VBN
cord-288231-vg8bwed9	84	6	experimentally	experimentally	RB
cord-288231-vg8bwed9	84	7	by	by	IN
cord-288231-vg8bwed9	84	8	demonstrating	demonstrate	VBG
cord-288231-vg8bwed9	84	9	that	that	IN
cord-288231-vg8bwed9	84	10	SARS	SARS	NNP
cord-288231-vg8bwed9	84	11	-	-	HYPH
cord-288231-vg8bwed9	84	12	CoV	CoV	NNP
cord-288231-vg8bwed9	84	13	infection	infection	NN
cord-288231-vg8bwed9	84	14	of	of	IN
cord-288231-vg8bwed9	84	15	diverse	diverse	JJ
cord-288231-vg8bwed9	84	16	cell	cell	NN
cord-288231-vg8bwed9	84	17	types	type	NNS
cord-288231-vg8bwed9	84	18	induces	induce	VBZ
cord-288231-vg8bwed9	84	19	a	a	DT
cord-288231-vg8bwed9	84	20	range	range	NN
cord-288231-vg8bwed9	84	21	of	of	IN
cord-288231-vg8bwed9	84	22	cytokines	cytokine	NNS
cord-288231-vg8bwed9	84	23	and	and	CC
cord-288231-vg8bwed9	84	24	chemokines	chemokine	NNS
cord-288231-vg8bwed9	84	25	,	,	,
cord-288231-vg8bwed9	84	26	thus	thus	RB
cord-288231-vg8bwed9	84	27	providing	provide	VBG
cord-288231-vg8bwed9	84	28	a	a	DT
cord-288231-vg8bwed9	84	29	conceptual	conceptual	JJ
cord-288231-vg8bwed9	84	30	framework	framework	NN
cord-288231-vg8bwed9	84	31	for	for	IN
cord-288231-vg8bwed9	84	32	SARS	SARS	NNP
cord-288231-vg8bwed9	84	33	-	-	HYPH
cord-288231-vg8bwed9	84	34	CoV	CoV	NNP
cord-288231-vg8bwed9	84	35	pathogenesis	pathogenesis	NN
cord-288231-vg8bwed9	84	36	.	.	.
cord-288231-vg8bwed9	85	1	Host	host	NN
cord-288231-vg8bwed9	85	2	genome	genome	NN
cord-288231-vg8bwed9	85	3	expression	expression	NN
cord-288231-vg8bwed9	85	4	analyses	analysis	NNS
cord-288231-vg8bwed9	85	5	of	of	IN
cord-288231-vg8bwed9	85	6	various	various	JJ
cord-288231-vg8bwed9	85	7	animal	animal	NN
cord-288231-vg8bwed9	85	8	hosts	host	NNS
cord-288231-vg8bwed9	85	9	and	and	CC
cord-288231-vg8bwed9	85	10	humans	human	NNS
cord-288231-vg8bwed9	85	11	with	with	IN
cord-288231-vg8bwed9	85	12	different	different	JJ
cord-288231-vg8bwed9	85	13	outcomes	outcome	NNS
cord-288231-vg8bwed9	85	14	of	of	IN
cord-288231-vg8bwed9	85	15	infection	infection	NN
cord-288231-vg8bwed9	85	16	indicated	indicate	VBD
cord-288231-vg8bwed9	85	17	differential	differential	JJ
cord-288231-vg8bwed9	85	18	activation	activation	NN
cord-288231-vg8bwed9	85	19	of	of	IN
cord-288231-vg8bwed9	85	20	innate	innate	JJ
cord-288231-vg8bwed9	85	21	immune	immune	JJ
cord-288231-vg8bwed9	85	22	genes	gene	NNS
cord-288231-vg8bwed9	85	23	in	in	IN
cord-288231-vg8bwed9	85	24	,	,	,
cord-288231-vg8bwed9	85	25	for	for	IN
cord-288231-vg8bwed9	85	26	example	example	NN
cord-288231-vg8bwed9	85	27	,	,	,
cord-288231-vg8bwed9	85	28	aged	aged	JJ
cord-288231-vg8bwed9	85	29	subjects	subject	NNS
cord-288231-vg8bwed9	85	30	compared	compare	VBN
cord-288231-vg8bwed9	85	31	to	to	IN
cord-288231-vg8bwed9	85	32	young	young	JJ
cord-288231-vg8bwed9	85	33	subjects	subject	NNS
cord-288231-vg8bwed9	85	34	.	.	.
cord-288231-vg8bwed9	86	1	Importantly	importantly	RB
cord-288231-vg8bwed9	86	2	,	,	,
cord-288231-vg8bwed9	86	3	treatment	treatment	NN
cord-288231-vg8bwed9	86	4	of	of	IN
cord-288231-vg8bwed9	86	5	aged	aged	JJ
cord-288231-vg8bwed9	86	6	macaques	macaque	NNS
cord-288231-vg8bwed9	86	7	with	with	IN
cord-288231-vg8bwed9	86	8	pegylated	pegylated	JJ
cord-288231-vg8bwed9	86	9	interferon	interferon	NN
cord-288231-vg8bwed9	86	10	-	-	HYPH
cord-288231-vg8bwed9	86	11	a	a	NN
cord-288231-vg8bwed9	86	12	(	(	-LRB-
cord-288231-vg8bwed9	86	13	i.e.	i.e.	FW
cord-288231-vg8bwed9	86	14	interferon	interferon	NN
cord-288231-vg8bwed9	86	15	-	-	:
cord-288231-vg8bwed9	86	16	a	a	DT
cord-288231-vg8bwed9	86	17	covalently	covalently	RB
cord-288231-vg8bwed9	86	18	modified	modify	VBN
cord-288231-vg8bwed9	86	19	with	with	IN
cord-288231-vg8bwed9	86	20	polyethylene	polyethylene	NN
cord-288231-vg8bwed9	86	21	glycol	glycol	NN
cord-288231-vg8bwed9	86	22	polymer	polymer	NN
cord-288231-vg8bwed9	86	23	chains	chain	NNS
cord-288231-vg8bwed9	86	24	,	,	,
cord-288231-vg8bwed9	86	25	to	to	TO
cord-288231-vg8bwed9	86	26	enhance	enhance	VB
cord-288231-vg8bwed9	86	27	its	-PRON-	PRP$
cord-288231-vg8bwed9	86	28	bioavailability	bioavailability	NN
cord-288231-vg8bwed9	86	29	)	)	-RRB-
cord-288231-vg8bwed9	86	30	reduced	reduce	VBN
cord-288231-vg8bwed9	86	31	SARS	SARS	NNP
cord-288231-vg8bwed9	86	32	-	-	HYPH
cord-288231-vg8bwed9	86	33	CoV	cov	NN
cord-288231-vg8bwed9	86	34	replication	replication	NN
cord-288231-vg8bwed9	86	35	and	and	CC
cord-288231-vg8bwed9	86	36	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	86	37	responses	response	NNS
cord-288231-vg8bwed9	86	38	[	[	-LRB-
cord-288231-vg8bwed9	86	39	28	28	CD
cord-288231-vg8bwed9	86	40	]	]	-RRB-
cord-288231-vg8bwed9	86	41	.	.	.
cord-288231-vg8bwed9	87	1	Thus	thus	RB
cord-288231-vg8bwed9	87	2	,	,	,
cord-288231-vg8bwed9	87	3	host	host	NN
cord-288231-vg8bwed9	87	4	genomics	genomic	NNS
cord-288231-vg8bwed9	87	5	analysis	analysis	NN
cord-288231-vg8bwed9	87	6	may	may	MD
cord-288231-vg8bwed9	87	7	provide	provide	VB
cord-288231-vg8bwed9	87	8	markers	marker	NNS
cord-288231-vg8bwed9	87	9	of	of	IN
cord-288231-vg8bwed9	87	10	pathogenesis	pathogenesis	NN
cord-288231-vg8bwed9	87	11	and	and	CC
cord-288231-vg8bwed9	87	12	leads	lead	VBZ
cord-288231-vg8bwed9	87	13	for	for	IN
cord-288231-vg8bwed9	87	14	therapeutic	therapeutic	JJ
cord-288231-vg8bwed9	87	15	intervention	intervention	NN
cord-288231-vg8bwed9	87	16	,	,	,
cord-288231-vg8bwed9	87	17	as	as	IN
cord-288231-vg8bwed9	87	18	in	in	IN
cord-288231-vg8bwed9	87	19	this	this	DT
cord-288231-vg8bwed9	87	20	example	example	NN
cord-288231-vg8bwed9	87	21	of	of	IN
cord-288231-vg8bwed9	87	22	SARS	SARS	NNP
cord-288231-vg8bwed9	87	23	-	-	HYPH
cord-288231-vg8bwed9	87	24	CoV	CoV	NNP
cord-288231-vg8bwed9	87	25	infection	infection	NN
cord-288231-vg8bwed9	87	26	.	.	.
cord-288231-vg8bwed9	88	1	Rapid	rapid	JJ
cord-288231-vg8bwed9	88	2	identification	identification	NN
cord-288231-vg8bwed9	88	3	of	of	IN
cord-288231-vg8bwed9	88	4	newly	newly	RB
cord-288231-vg8bwed9	88	5	emerging	emerge	VBG
cord-288231-vg8bwed9	88	6	viruses	virus	NNS
cord-288231-vg8bwed9	88	7	through	through	IN
cord-288231-vg8bwed9	88	8	the	the	DT
cord-288231-vg8bwed9	88	9	use	use	NN
cord-288231-vg8bwed9	88	10	of	of	IN
cord-288231-vg8bwed9	88	11	genomics	genomic	NNS
cord-288231-vg8bwed9	88	12	tools	tool	NNS
cord-288231-vg8bwed9	88	13	is	be	VBZ
cord-288231-vg8bwed9	88	14	one	one	CD
cord-288231-vg8bwed9	88	15	of	of	IN
cord-288231-vg8bwed9	88	16	the	the	DT
cord-288231-vg8bwed9	88	17	major	major	JJ
cord-288231-vg8bwed9	88	18	challenges	challenge	NNS
cord-288231-vg8bwed9	88	19	for	for	IN
cord-288231-vg8bwed9	88	20	the	the	DT
cord-288231-vg8bwed9	88	21	near	near	JJ
cord-288231-vg8bwed9	88	22	future	future	NN
cord-288231-vg8bwed9	88	23	.	.	.
cord-288231-vg8bwed9	89	1	In	in	IN
cord-288231-vg8bwed9	89	2	addition	addition	NN
cord-288231-vg8bwed9	89	3	,	,	,
cord-288231-vg8bwed9	89	4	the	the	DT
cord-288231-vg8bwed9	89	5	identification	identification	NN
cord-288231-vg8bwed9	89	6	of	of	IN
cord-288231-vg8bwed9	89	7	critical	critical	JJ
cord-288231-vg8bwed9	89	8	mutations	mutation	NNS
cord-288231-vg8bwed9	89	9	that	that	WDT
cord-288231-vg8bwed9	89	10	enable	enable	VBP
cord-288231-vg8bwed9	89	11	viruses	virus	NNS
cord-288231-vg8bwed9	89	12	to	to	TO
cord-288231-vg8bwed9	89	13	spread	spread	VB
cord-288231-vg8bwed9	89	14	efficiently	efficiently	RB
cord-288231-vg8bwed9	89	15	,	,	,
cord-288231-vg8bwed9	89	16	interact	interact	VB
cord-288231-vg8bwed9	89	17	with	with	IN
cord-288231-vg8bwed9	89	18	different	different	JJ
cord-288231-vg8bwed9	89	19	receptors	receptor	NNS
cord-288231-vg8bwed9	89	20	,	,	,
cord-288231-vg8bwed9	89	21	and	and	CC
cord-288231-vg8bwed9	89	22	cause	cause	VB
cord-288231-vg8bwed9	89	23	disease	disease	NN
cord-288231-vg8bwed9	89	24	in	in	IN
cord-288231-vg8bwed9	89	25	diverse	diverse	JJ
cord-288231-vg8bwed9	89	26	hosts	host	NNS
cord-288231-vg8bwed9	89	27	through	through	IN
cord-288231-vg8bwed9	89	28	,	,	,
cord-288231-vg8bwed9	89	29	for	for	IN
cord-288231-vg8bwed9	89	30	instance	instance	NN
cord-288231-vg8bwed9	89	31	,	,	,
cord-288231-vg8bwed9	89	32	enhanced	enhance	VBN
cord-288231-vg8bwed9	89	33	viral	viral	JJ
cord-288231-vg8bwed9	89	34	replication	replication	NN
cord-288231-vg8bwed9	89	35	or	or	CC
cord-288231-vg8bwed9	89	36	circumvention	circumvention	NN
cord-288231-vg8bwed9	89	37	of	of	IN
cord-288231-vg8bwed9	89	38	the	the	DT
cord-288231-vg8bwed9	89	39	innate	innate	JJ
cord-288231-vg8bwed9	89	40	and	and	CC
cord-288231-vg8bwed9	89	41	adaptive	adaptive	JJ
cord-288231-vg8bwed9	89	42	immune	immune	JJ
cord-288231-vg8bwed9	89	43	responses	response	NNS
cord-288231-vg8bwed9	89	44	,	,	,
cord-288231-vg8bwed9	89	45	needs	need	VBZ
cord-288231-vg8bwed9	89	46	to	to	TO
cord-288231-vg8bwed9	89	47	be	be	VB
cord-288231-vg8bwed9	89	48	further	further	RB
cord-288231-vg8bwed9	89	49	expanded	expand	VBN
cord-288231-vg8bwed9	89	50	.	.	.
cord-288231-vg8bwed9	90	1	Although	although	IN
cord-288231-vg8bwed9	90	2	microarrayassisted	microarrayassisted	JJ
cord-288231-vg8bwed9	90	3	transcriptional	transcriptional	JJ
cord-288231-vg8bwed9	90	4	profiling	profiling	NN
cord-288231-vg8bwed9	90	5	can	can	MD
cord-288231-vg8bwed9	90	6	provide	provide	VB
cord-288231-vg8bwed9	90	7	us	-PRON-	PRP
cord-288231-vg8bwed9	90	8	with	with	IN
cord-288231-vg8bwed9	90	9	a	a	DT
cord-288231-vg8bwed9	90	10	wealth	wealth	NN
cord-288231-vg8bwed9	90	11	of	of	IN
cord-288231-vg8bwed9	90	12	information	information	NN
cord-288231-vg8bwed9	90	13	regarding	regard	VBG
cord-288231-vg8bwed9	90	14	host	host	NN
cord-288231-vg8bwed9	90	15	genes	gene	NNS
cord-288231-vg8bwed9	90	16	and	and	CC
cord-288231-vg8bwed9	90	17	gene	gene	NN
cord-288231-vg8bwed9	90	18	-	-	HYPH
cord-288231-vg8bwed9	90	19	interacting	interact	VBG
cord-288231-vg8bwed9	90	20	networks	network	NNS
cord-288231-vg8bwed9	90	21	in	in	IN
cord-288231-vg8bwed9	90	22	Figure	figure	NN
cord-288231-vg8bwed9	90	23	2	2	CD
cord-288231-vg8bwed9	90	24	.	.	.
cord-288231-vg8bwed9	91	1	Zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	91	2	transmission	transmission	NN
cord-288231-vg8bwed9	91	3	of	of	IN
cord-288231-vg8bwed9	91	4	SARS	SARS	NNP
cord-288231-vg8bwed9	91	5	-	-	HYPH
cord-288231-vg8bwed9	91	6	CoV.	CoV.	NNP
cord-288231-vg8bwed9	91	7	Genomic	Genomic	NNP
cord-288231-vg8bwed9	91	8	analyses	analysis	NNS
cord-288231-vg8bwed9	91	9	provided	provide	VBD
cord-288231-vg8bwed9	91	10	evidence	evidence	NN
cord-288231-vg8bwed9	91	11	that	that	IN
cord-288231-vg8bwed9	91	12	genetic	genetic	JJ
cord-288231-vg8bwed9	91	13	changes	change	NNS
cord-288231-vg8bwed9	91	14	in	in	IN
cord-288231-vg8bwed9	91	15	the	the	DT
cord-288231-vg8bwed9	91	16	spike	spike	NN
cord-288231-vg8bwed9	91	17	gene	gene	NN
cord-288231-vg8bwed9	91	18	of	of	IN
cord-288231-vg8bwed9	91	19	SARS	SARS	NNP
cord-288231-vg8bwed9	91	20	-	-	HYPH
cord-288231-vg8bwed9	91	21	CoV	CoV	NNP
cord-288231-vg8bwed9	91	22	from	from	IN
cord-288231-vg8bwed9	91	23	bats	bat	NNS
cord-288231-vg8bwed9	91	24	(	(	-LRB-
cord-288231-vg8bwed9	91	25	left	left	NN
cord-288231-vg8bwed9	91	26	)	)	-RRB-
cord-288231-vg8bwed9	91	27	and	and	CC
cord-288231-vg8bwed9	91	28	civet	civet	NN
cord-288231-vg8bwed9	91	29	cats	cat	NNS
cord-288231-vg8bwed9	91	30	(	(	-LRB-
cord-288231-vg8bwed9	91	31	center	center	NN
cord-288231-vg8bwed9	91	32	)	)	-RRB-
cord-288231-vg8bwed9	91	33	are	be	VBP
cord-288231-vg8bwed9	91	34	essential	essential	JJ
cord-288231-vg8bwed9	91	35	for	for	IN
cord-288231-vg8bwed9	91	36	the	the	DT
cord-288231-vg8bwed9	91	37	animal	animal	NN
cord-288231-vg8bwed9	91	38	-	-	HYPH
cord-288231-vg8bwed9	91	39	to	to	IN
cord-288231-vg8bwed9	91	40	-	-	HYPH
cord-288231-vg8bwed9	91	41	human	human	JJ
cord-288231-vg8bwed9	91	42	transmission	transmission	NN
cord-288231-vg8bwed9	91	43	(	(	-LRB-
cord-288231-vg8bwed9	91	44	horizontal	horizontal	JJ
cord-288231-vg8bwed9	91	45	arrows	arrow	NNS
cord-288231-vg8bwed9	91	46	)	)	-RRB-
cord-288231-vg8bwed9	91	47	.	.	.
cord-288231-vg8bwed9	92	1	Species	species	NN
cord-288231-vg8bwed9	92	2	-	-	HYPH
cord-288231-vg8bwed9	92	3	to	to	IN
cord-288231-vg8bwed9	92	4	-	-	HYPH
cord-288231-vg8bwed9	92	5	species	species	NN
cord-288231-vg8bwed9	92	6	genetic	genetic	JJ
cord-288231-vg8bwed9	92	7	variation	variation	NN
cord-288231-vg8bwed9	92	8	in	in	IN
cord-288231-vg8bwed9	92	9	the	the	DT
cord-288231-vg8bwed9	92	10	(	(	-LRB-
cord-288231-vg8bwed9	92	11	thus	thus	RB
cord-288231-vg8bwed9	92	12	far	far	RB
cord-288231-vg8bwed9	92	13	unidentified	unidentified	JJ
cord-288231-vg8bwed9	92	14	)	)	-RRB-
cord-288231-vg8bwed9	92	15	viral	viral	JJ
cord-288231-vg8bwed9	92	16	receptor	receptor	NN
cord-288231-vg8bwed9	92	17	in	in	IN
cord-288231-vg8bwed9	92	18	bats	bat	NNS
cord-288231-vg8bwed9	92	19	and	and	CC
cord-288231-vg8bwed9	92	20	in	in	IN
cord-288231-vg8bwed9	92	21	the	the	DT
cord-288231-vg8bwed9	92	22	angiotensin	angiotensin	NN
cord-288231-vg8bwed9	92	23	converting	convert	VBG
cord-288231-vg8bwed9	92	24	enzyme	enzyme	NN
cord-288231-vg8bwed9	92	25	2	2	CD
cord-288231-vg8bwed9	92	26	(	(	-LRB-
cord-288231-vg8bwed9	92	27	ACE2	ACE2	NNP
cord-288231-vg8bwed9	92	28	)	)	-RRB-
cord-288231-vg8bwed9	92	29	gene	gene	NN
cord-288231-vg8bwed9	92	30	,	,	,
cord-288231-vg8bwed9	92	31	encoding	encode	VBG
cord-288231-vg8bwed9	92	32	the	the	DT
cord-288231-vg8bwed9	92	33	SARS	SARS	NNP
cord-288231-vg8bwed9	92	34	-	-	HYPH
cord-288231-vg8bwed9	92	35	CoV	CoV	NNP
cord-288231-vg8bwed9	92	36	receptor	receptor	NN
cord-288231-vg8bwed9	92	37	in	in	IN
cord-288231-vg8bwed9	92	38	civet	civet	NN
cord-288231-vg8bwed9	92	39	cats	cat	NNS
cord-288231-vg8bwed9	92	40	and	and	CC
cord-288231-vg8bwed9	92	41	humans	human	NNS
cord-288231-vg8bwed9	92	42	also	also	RB
cord-288231-vg8bwed9	92	43	affects	affect	VBZ
cord-288231-vg8bwed9	92	44	the	the	DT
cord-288231-vg8bwed9	92	45	efficiency	efficiency	NN
cord-288231-vg8bwed9	92	46	with	with	IN
cord-288231-vg8bwed9	92	47	which	which	WDT
cord-288231-vg8bwed9	92	48	the	the	DT
cord-288231-vg8bwed9	92	49	virus	virus	NN
cord-288231-vg8bwed9	92	50	can	can	MD
cord-288231-vg8bwed9	92	51	enter	enter	VB
cord-288231-vg8bwed9	92	52	cells	cell	NNS
cord-288231-vg8bwed9	92	53	(	(	-LRB-
cord-288231-vg8bwed9	92	54	vertical	vertical	JJ
cord-288231-vg8bwed9	92	55	arrows	arrow	NNS
cord-288231-vg8bwed9	92	56	)	)	-RRB-
cord-288231-vg8bwed9	92	57	.	.	.
cord-288231-vg8bwed9	93	1	The	the	DT
cord-288231-vg8bwed9	93	2	SARS	SARS	NNP
cord-288231-vg8bwed9	93	3	-	-	HYPH
cord-288231-vg8bwed9	93	4	CoV	CoV	NNP
cord-288231-vg8bwed9	93	5	that	that	WDT
cord-288231-vg8bwed9	93	6	caused	cause	VBD
cord-288231-vg8bwed9	93	7	the	the	DT
cord-288231-vg8bwed9	93	8	epidemic	epidemic	NN
cord-288231-vg8bwed9	93	9	evolved	evolve	VBD
cord-288231-vg8bwed9	93	10	a	a	DT
cord-288231-vg8bwed9	93	11	high	high	JJ
cord-288231-vg8bwed9	93	12	affinity	affinity	NN
cord-288231-vg8bwed9	93	13	for	for	IN
cord-288231-vg8bwed9	93	14	both	both	DT
cord-288231-vg8bwed9	93	15	civet	civet	NN
cord-288231-vg8bwed9	93	16	(	(	-LRB-
cord-288231-vg8bwed9	93	17	center	center	NN
cord-288231-vg8bwed9	93	18	)	)	-RRB-
cord-288231-vg8bwed9	93	19	and	and	CC
cord-288231-vg8bwed9	93	20	human	human	JJ
cord-288231-vg8bwed9	93	21	(	(	-LRB-
cord-288231-vg8bwed9	93	22	right	right	NN
cord-288231-vg8bwed9	93	23	)	)	-RRB-
cord-288231-vg8bwed9	94	1	ACE2	ACE2	NNP
cord-288231-vg8bwed9	94	2	receptors	receptor	NNS
cord-288231-vg8bwed9	94	3	(	(	-LRB-
cord-288231-vg8bwed9	94	4	indicated	indicate	VBN
cord-288231-vg8bwed9	94	5	by	by	IN
cord-288231-vg8bwed9	94	6	the	the	DT
cord-288231-vg8bwed9	94	7	single	single	JJ
cord-288231-vg8bwed9	94	8	diagonal	diagonal	NN
cord-288231-vg8bwed9	94	9	and	and	CC
cord-288231-vg8bwed9	94	10	the	the	DT
cord-288231-vg8bwed9	94	11	right	right	JJ
cord-288231-vg8bwed9	94	12	side	side	NN
cord-288231-vg8bwed9	94	13	vertical	vertical	JJ
cord-288231-vg8bwed9	94	14	arrow	arrow	NN
cord-288231-vg8bwed9	94	15	)	)	-RRB-
cord-288231-vg8bwed9	94	16	.	.	.
cord-288231-vg8bwed9	95	1	virus	virus	NN
cord-288231-vg8bwed9	95	2	-	-	HYPH
cord-288231-vg8bwed9	95	3	host	host	NN
cord-288231-vg8bwed9	95	4	interactions	interaction	NNS
cord-288231-vg8bwed9	95	5	,	,	,
cord-288231-vg8bwed9	95	6	future	future	JJ
cord-288231-vg8bwed9	95	7	research	research	NN
cord-288231-vg8bwed9	95	8	should	should	MD
cord-288231-vg8bwed9	95	9	focus	focus	VB
cord-288231-vg8bwed9	95	10	on	on	IN
cord-288231-vg8bwed9	95	11	combining	combine	VBG
cord-288231-vg8bwed9	95	12	data	datum	NNS
cord-288231-vg8bwed9	95	13	obtained	obtain	VBN
cord-288231-vg8bwed9	95	14	in	in	IN
cord-288231-vg8bwed9	95	15	different	different	JJ
cord-288231-vg8bwed9	95	16	experimental	experimental	JJ
cord-288231-vg8bwed9	95	17	settings	setting	NNS
cord-288231-vg8bwed9	95	18	.	.	.
cord-288231-vg8bwed9	96	1	Therefore	therefore	RB
cord-288231-vg8bwed9	96	2	,	,	,
cord-288231-vg8bwed9	96	3	the	the	DT
cord-288231-vg8bwed9	96	4	careful	careful	JJ
cord-288231-vg8bwed9	96	5	design	design	NN
cord-288231-vg8bwed9	96	6	of	of	IN
cord-288231-vg8bwed9	96	7	complementary	complementary	JJ
cord-288231-vg8bwed9	96	8	sets	set	NNS
cord-288231-vg8bwed9	96	9	of	of	IN
cord-288231-vg8bwed9	96	10	experiments	experiment	NNS
cord-288231-vg8bwed9	96	11	using	use	VBG
cord-288231-vg8bwed9	96	12	different	different	JJ
cord-288231-vg8bwed9	96	13	formats	format	NNS
cord-288231-vg8bwed9	96	14	of	of	IN
cord-288231-vg8bwed9	96	15	virus	virus	NN
cord-288231-vg8bwed9	96	16	-	-	HYPH
cord-288231-vg8bwed9	96	17	host	host	NN
cord-288231-vg8bwed9	96	18	interactions	interaction	NNS
cord-288231-vg8bwed9	96	19	is	be	VBZ
cord-288231-vg8bwed9	96	20	absolutely	absolutely	RB
cord-288231-vg8bwed9	96	21	needed	need	VBN
cord-288231-vg8bwed9	96	22	for	for	IN
cord-288231-vg8bwed9	96	23	successful	successful	JJ
cord-288231-vg8bwed9	96	24	genomics	genomic	NNS
cord-288231-vg8bwed9	96	25	studies	study	NNS
cord-288231-vg8bwed9	96	26	[	[	-LRB-
cord-288231-vg8bwed9	96	27	29	29	CD
cord-288231-vg8bwed9	96	28	]	]	-RRB-
cord-288231-vg8bwed9	96	29	.	.	.
cord-288231-vg8bwed9	97	1	Special	special	JJ
cord-288231-vg8bwed9	97	2	attention	attention	NN
cord-288231-vg8bwed9	97	3	should	should	MD
cord-288231-vg8bwed9	97	4	be	be	VB
cord-288231-vg8bwed9	97	5	addressed	address	VBN
cord-288231-vg8bwed9	97	6	to	to	IN
cord-288231-vg8bwed9	97	7	the	the	DT
cord-288231-vg8bwed9	97	8	comparative	comparative	JJ
cord-288231-vg8bwed9	97	9	analysis	analysis	NN
cord-288231-vg8bwed9	97	10	of	of	IN
cord-288231-vg8bwed9	97	11	the	the	DT
cord-288231-vg8bwed9	97	12	host	host	NN
cord-288231-vg8bwed9	97	13	response	response	NN
cord-288231-vg8bwed9	97	14	in	in	IN
cord-288231-vg8bwed9	97	15	diverse	diverse	JJ
cord-288231-vg8bwed9	97	16	animal	animal	NN
cord-288231-vg8bwed9	97	17	species	specie	NNS
cord-288231-vg8bwed9	97	18	.	.	.
cord-288231-vg8bwed9	98	1	Thus	thus	RB
cord-288231-vg8bwed9	98	2	far	far	RB
cord-288231-vg8bwed9	98	3	a	a	DT
cord-288231-vg8bwed9	98	4	limited	limited	JJ
cord-288231-vg8bwed9	98	5	number	number	NN
cord-288231-vg8bwed9	98	6	of	of	IN
cord-288231-vg8bwed9	98	7	laboratory	laboratory	NN
cord-288231-vg8bwed9	98	8	animal	animal	NN
cord-288231-vg8bwed9	98	9	species	specie	NNS
cord-288231-vg8bwed9	98	10	has	have	VBZ
cord-288231-vg8bwed9	98	11	been	be	VBN
cord-288231-vg8bwed9	98	12	studied	study	VBN
cord-288231-vg8bwed9	98	13	,	,	,
cord-288231-vg8bwed9	98	14	but	but	CC
cord-288231-vg8bwed9	98	15	the	the	DT
cord-288231-vg8bwed9	98	16	recent	recent	JJ
cord-288231-vg8bwed9	98	17	elucidation	elucidation	NN
cord-288231-vg8bwed9	98	18	of	of	IN
cord-288231-vg8bwed9	98	19	the	the	DT
cord-288231-vg8bwed9	98	20	genome	genome	NN
cord-288231-vg8bwed9	98	21	of	of	IN
cord-288231-vg8bwed9	98	22	several	several	JJ
cord-288231-vg8bwed9	98	23	other	other	JJ
cord-288231-vg8bwed9	98	24	animal	animal	NN
cord-288231-vg8bwed9	98	25	species	specie	NNS
cord-288231-vg8bwed9	98	26	will	will	MD
cord-288231-vg8bwed9	98	27	provide	provide	VB
cord-288231-vg8bwed9	98	28	tools	tool	NNS
cord-288231-vg8bwed9	98	29	to	to	TO
cord-288231-vg8bwed9	98	30	decipher	decipher	VB
cord-288231-vg8bwed9	98	31	the	the	DT
cord-288231-vg8bwed9	98	32	virus	virus	NN
cord-288231-vg8bwed9	98	33	-	-	HYPH
cord-288231-vg8bwed9	98	34	host	host	NN
cord-288231-vg8bwed9	98	35	interactions	interaction	NNS
cord-288231-vg8bwed9	98	36	in	in	IN
cord-288231-vg8bwed9	98	37	the	the	DT
cord-288231-vg8bwed9	98	38	more	more	RBR
cord-288231-vg8bwed9	98	39	relevant	relevant	JJ
cord-288231-vg8bwed9	98	40	natural	natural	JJ
cord-288231-vg8bwed9	98	41	host	host	NN
cord-288231-vg8bwed9	98	42	.	.	.
cord-288231-vg8bwed9	99	1	Recent	recent	JJ
cord-288231-vg8bwed9	99	2	developments	development	NNS
cord-288231-vg8bwed9	99	3	in	in	IN
cord-288231-vg8bwed9	99	4	the	the	DT
cord-288231-vg8bwed9	99	5	sequencing	sequencing	NN
cord-288231-vg8bwed9	99	6	of	of	IN
cord-288231-vg8bwed9	99	7	the	the	DT
cord-288231-vg8bwed9	99	8	RNA	RNA	NNP
cord-288231-vg8bwed9	99	9	transcriptome	transcriptome	NN
cord-288231-vg8bwed9	99	10	may	may	MD
cord-288231-vg8bwed9	99	11	aid	aid	VB
cord-288231-vg8bwed9	99	12	this	this	DT
cord-288231-vg8bwed9	99	13	development	development	NN
cord-288231-vg8bwed9	99	14	.	.	.
cord-288231-vg8bwed9	100	1	Ultimately	ultimately	RB
cord-288231-vg8bwed9	100	2	,	,	,
cord-288231-vg8bwed9	100	3	microarray	microarray	NN
cord-288231-vg8bwed9	100	4	technology	technology	NN
cord-288231-vg8bwed9	100	5	may	may	MD
cord-288231-vg8bwed9	100	6	also	also	RB
cord-288231-vg8bwed9	100	7	extend	extend	VB
cord-288231-vg8bwed9	100	8	to	to	IN
cord-288231-vg8bwed9	100	9	genotyping	genotyping	NN
cord-288231-vg8bwed9	100	10	of	of	IN
cord-288231-vg8bwed9	100	11	the	the	DT
cord-288231-vg8bwed9	100	12	human	human	JJ
cord-288231-vg8bwed9	100	13	host	host	NN
cord-288231-vg8bwed9	100	14	by	by	IN
cord-288231-vg8bwed9	100	15	SNP	SNP	NNP
cord-288231-vg8bwed9	100	16	analysis	analysis	NN
cord-288231-vg8bwed9	100	17	,	,	,
cord-288231-vg8bwed9	100	18	to	to	TO
cord-288231-vg8bwed9	100	19	identify	identify	VB
cord-288231-vg8bwed9	100	20	markers	marker	NNS
cord-288231-vg8bwed9	100	21	of	of	IN
cord-288231-vg8bwed9	100	22	host	host	NN
cord-288231-vg8bwed9	100	23	susceptibility	susceptibility	NN
cord-288231-vg8bwed9	100	24	and	and	CC
cord-288231-vg8bwed9	100	25	severity	severity	NN
cord-288231-vg8bwed9	100	26	of	of	IN
cord-288231-vg8bwed9	100	27	disease	disease	NN
cord-288231-vg8bwed9	100	28	,	,	,
cord-288231-vg8bwed9	100	29	that	that	WDT
cord-288231-vg8bwed9	100	30	can	can	MD
cord-288231-vg8bwed9	100	31	be	be	VB
cord-288231-vg8bwed9	100	32	used	use	VBN
cord-288231-vg8bwed9	100	33	in	in	IN
cord-288231-vg8bwed9	100	34	tailor	tailor	NN
cord-288231-vg8bwed9	100	35	-	-	HYPH
cord-288231-vg8bwed9	100	36	made	make	VBN
cord-288231-vg8bwed9	100	37	clinical	clinical	JJ
cord-288231-vg8bwed9	100	38	management	management	NN
cord-288231-vg8bwed9	100	39	of	of	IN
cord-288231-vg8bwed9	100	40	disease	disease	NN
cord-288231-vg8bwed9	100	41	caused	cause	VBN
cord-288231-vg8bwed9	100	42	by	by	IN
cord-288231-vg8bwed9	100	43	emerging	emerge	VBG
cord-288231-vg8bwed9	100	44	infections	infection	NNS
cord-288231-vg8bwed9	100	45	.	.	.
cord-288231-vg8bwed9	101	1	Comparative	comparative	JJ
cord-288231-vg8bwed9	101	2	analysis	analysis	NN
cord-288231-vg8bwed9	101	3	of	of	IN
cord-288231-vg8bwed9	101	4	host	host	NN
cord-288231-vg8bwed9	101	5	responses	response	NNS
cord-288231-vg8bwed9	101	6	to	to	IN
cord-288231-vg8bwed9	101	7	emerging	emerge	VBG
cord-288231-vg8bwed9	101	8	viruses	virus	NNS
cord-288231-vg8bwed9	101	9	may	may	MD
cord-288231-vg8bwed9	101	10	also	also	RB
cord-288231-vg8bwed9	101	11	point	point	VB
cord-288231-vg8bwed9	101	12	toward	toward	IN
cord-288231-vg8bwed9	101	13	a	a	DT
cord-288231-vg8bwed9	101	14	similar	similar	JJ
cord-288231-vg8bwed9	101	15	dysregulated	dysregulate	VBN
cord-288231-vg8bwed9	101	16	host	host	NN
cord-288231-vg8bwed9	101	17	response	response	NN
cord-288231-vg8bwed9	101	18	to	to	IN
cord-288231-vg8bwed9	101	19	a	a	DT
cord-288231-vg8bwed9	101	20	range	range	NN
cord-288231-vg8bwed9	101	21	of	of	IN
cord-288231-vg8bwed9	101	22	emerging	emerge	VBG
cord-288231-vg8bwed9	101	23	virus	virus	NN
cord-288231-vg8bwed9	101	24	infections	infection	NNS
cord-288231-vg8bwed9	101	25	,	,	,
cord-288231-vg8bwed9	101	26	enabling	enable	VBG
cord-288231-vg8bwed9	101	27	the	the	DT
cord-288231-vg8bwed9	101	28	rational	rational	JJ
cord-288231-vg8bwed9	101	29	design	design	NN
cord-288231-vg8bwed9	101	30	of	of	IN
cord-288231-vg8bwed9	101	31	multipotent	multipotent	JJ
cord-288231-vg8bwed9	101	32	biological	biological	JJ
cord-288231-vg8bwed9	101	33	response	response	NN
cord-288231-vg8bwed9	101	34	modifiers	modifier	NNS
cord-288231-vg8bwed9	101	35	to	to	TO
cord-288231-vg8bwed9	101	36	combat	combat	VB
cord-288231-vg8bwed9	101	37	a	a	DT
cord-288231-vg8bwed9	101	38	variety	variety	NN
cord-288231-vg8bwed9	101	39	of	of	IN
cord-288231-vg8bwed9	101	40	emerging	emerge	VBG
cord-288231-vg8bwed9	101	41	viral	viral	JJ
cord-288231-vg8bwed9	101	42	infections	infection	NNS
cord-288231-vg8bwed9	101	43	.	.	.
cord-288231-vg8bwed9	102	1	By	by	IN
cord-288231-vg8bwed9	102	2	focusing	focus	VBG
cord-288231-vg8bwed9	102	3	on	on	IN
cord-288231-vg8bwed9	102	4	broad	broad	RB
cord-288231-vg8bwed9	102	5	-	-	HYPH
cord-288231-vg8bwed9	102	6	acting	act	VBG
cord-288231-vg8bwed9	102	7	intervention	intervention	NN
cord-288231-vg8bwed9	102	8	strategies	strategy	NNS
cord-288231-vg8bwed9	102	9	rather	rather	RB
cord-288231-vg8bwed9	102	10	than	than	IN
cord-288231-vg8bwed9	102	11	on	on	IN
cord-288231-vg8bwed9	102	12	the	the	DT
cord-288231-vg8bwed9	102	13	discovery	discovery	NN
cord-288231-vg8bwed9	102	14	of	of	IN
cord-288231-vg8bwed9	102	15	a	a	DT
cord-288231-vg8bwed9	102	16	newly	newly	RB
cord-288231-vg8bwed9	102	17	emerging	emerge	VBG
cord-288231-vg8bwed9	102	18	pathogen	pathogen	NN
cord-288231-vg8bwed9	102	19	that	that	WDT
cord-288231-vg8bwed9	102	20	is	be	VBZ
cord-288231-vg8bwed9	102	21	not	not	RB
cord-288231-vg8bwed9	102	22	characterized	characterize	VBN
cord-288231-vg8bwed9	102	23	yet	yet	RB
cord-288231-vg8bwed9	102	24	,	,	,
cord-288231-vg8bwed9	102	25	we	-PRON-	PRP
cord-288231-vg8bwed9	102	26	may	may	MD
cord-288231-vg8bwed9	102	27	be	be	VB
cord-288231-vg8bwed9	102	28	able	able	JJ
cord-288231-vg8bwed9	102	29	to	to	TO
cord-288231-vg8bwed9	102	30	protect	protect	VB
cord-288231-vg8bwed9	102	31	ourselves	-PRON-	PRP
cord-288231-vg8bwed9	102	32	from	from	IN
cord-288231-vg8bwed9	102	33	several	several	JJ
cord-288231-vg8bwed9	102	34	unexpectedly	unexpectedly	RB
cord-288231-vg8bwed9	102	35	emerging	emerge	VBG
cord-288231-vg8bwed9	102	36	infections	infection	NNS
cord-288231-vg8bwed9	102	37	with	with	IN
cord-288231-vg8bwed9	102	38	the	the	DT
cord-288231-vg8bwed9	102	39	same	same	JJ
cord-288231-vg8bwed9	102	40	clinical	clinical	JJ
cord-288231-vg8bwed9	102	41	manifestations	manifestation	NNS
cord-288231-vg8bwed9	102	42	.	.	.
cord-288231-vg8bwed9	103	1	This	this	DT
cord-288231-vg8bwed9	103	2	approach	approach	NN
cord-288231-vg8bwed9	103	3	may	may	MD
cord-288231-vg8bwed9	103	4	readily	readily	RB
cord-288231-vg8bwed9	103	5	reduce	reduce	VB
cord-288231-vg8bwed9	103	6	the	the	DT
cord-288231-vg8bwed9	103	7	burden	burden	NN
cord-288231-vg8bwed9	103	8	of	of	IN
cord-288231-vg8bwed9	103	9	disease	disease	NN
cord-288231-vg8bwed9	103	10	and	and	CC
cord-288231-vg8bwed9	103	11	time	time	NN
cord-288231-vg8bwed9	103	12	will	will	MD
cord-288231-vg8bwed9	103	13	be	be	VB
cord-288231-vg8bwed9	103	14	gained	gain	VBN
cord-288231-vg8bwed9	103	15	to	to	TO
cord-288231-vg8bwed9	103	16	design	design	VB
cord-288231-vg8bwed9	103	17	preventive	preventive	JJ
cord-288231-vg8bwed9	103	18	pathogen	pathogen	NN
cord-288231-vg8bwed9	103	19	specific	specific	JJ
cord-288231-vg8bwed9	103	20	intervention	intervention	NN
cord-288231-vg8bwed9	103	21	strategies	strategy	NNS
cord-288231-vg8bwed9	103	22	such	such	JJ
cord-288231-vg8bwed9	103	23	as	as	IN
cord-288231-vg8bwed9	103	24	antiviral	antiviral	JJ
cord-288231-vg8bwed9	103	25	therapy	therapy	NN
cord-288231-vg8bwed9	103	26	or	or	CC
cord-288231-vg8bwed9	103	27	vaccination	vaccination	NN
cord-288231-vg8bwed9	103	28	.	.	.
cord-288231-vg8bwed9	104	1	Clearly	clearly	RB
cord-288231-vg8bwed9	104	2	,	,	,
cord-288231-vg8bwed9	104	3	for	for	IN
cord-288231-vg8bwed9	104	4	all	all	DT
cord-288231-vg8bwed9	104	5	stages	stage	NNS
cord-288231-vg8bwed9	104	6	of	of	IN
cord-288231-vg8bwed9	104	7	combating	combat	VBG
cord-288231-vg8bwed9	104	8	emerging	emerge	VBG
cord-288231-vg8bwed9	104	9	infections	infection	NNS
cord-288231-vg8bwed9	104	10	,	,	,
cord-288231-vg8bwed9	104	11	from	from	IN
cord-288231-vg8bwed9	104	12	the	the	DT
cord-288231-vg8bwed9	104	13	early	early	JJ
cord-288231-vg8bwed9	104	14	identification	identification	NN
cord-288231-vg8bwed9	104	15	of	of	IN
cord-288231-vg8bwed9	104	16	the	the	DT
cord-288231-vg8bwed9	104	17	pathogen	pathogen	NN
cord-288231-vg8bwed9	104	18	to	to	IN
cord-288231-vg8bwed9	104	19	the	the	DT
cord-288231-vg8bwed9	104	20	development	development	NN
cord-288231-vg8bwed9	104	21	and	and	CC
cord-288231-vg8bwed9	104	22	design	design	NN
cord-288231-vg8bwed9	104	23	of	of	IN
cord-288231-vg8bwed9	104	24	vaccines	vaccine	NNS
cord-288231-vg8bwed9	104	25	,	,	,
cord-288231-vg8bwed9	104	26	application	application	NN
cord-288231-vg8bwed9	104	27	of	of	IN
cord-288231-vg8bwed9	104	28	sophisticated	sophisticated	JJ
cord-288231-vg8bwed9	104	29	genomics	genomic	NNS
cord-288231-vg8bwed9	104	30	tools	tool	NNS
cord-288231-vg8bwed9	104	31	is	be	VBZ
cord-288231-vg8bwed9	104	32	fundamental	fundamental	JJ
cord-288231-vg8bwed9	104	33	to	to	IN
cord-288231-vg8bwed9	104	34	success	success	NN
cord-288231-vg8bwed9	104	35	.	.	.
cord-288231-vg8bwed9	105	1	Catastrophes	catastrophe	NNS
cord-288231-vg8bwed9	105	2	after	after	IN
cord-288231-vg8bwed9	105	3	crossing	cross	VBG
cord-288231-vg8bwed9	105	4	species	species	NN
cord-288231-vg8bwed9	105	5	barriers	barrier	NNS
cord-288231-vg8bwed9	105	6	Public	public	JJ
cord-288231-vg8bwed9	105	7	health	health	NN
cord-288231-vg8bwed9	105	8	.	.	.
cord-288231-vg8bwed9	106	1	Pathogen	pathogen	NN
cord-288231-vg8bwed9	106	2	surveillance	surveillance	NN
cord-288231-vg8bwed9	106	3	in	in	IN
cord-288231-vg8bwed9	106	4	animals	animal	NNS
cord-288231-vg8bwed9	106	5	Henipaviruses	Henipaviruses	NNP
cord-288231-vg8bwed9	106	6	:	:	:
cord-288231-vg8bwed9	107	1	Emerging	emerge	VBG
cord-288231-vg8bwed9	107	2	paramyxoviruses	paramyxovirus	NNS
cord-288231-vg8bwed9	107	3	associated	associate	VBN
cord-288231-vg8bwed9	107	4	with	with	IN
cord-288231-vg8bwed9	107	5	fruit	fruit	NN
cord-288231-vg8bwed9	107	6	bats	bat	NNS
cord-288231-vg8bwed9	107	7	Viruses	Viruses	NNPS
cord-288231-vg8bwed9	107	8	and	and	CC
cord-288231-vg8bwed9	107	9	Koch	Koch	NNP
cord-288231-vg8bwed9	107	10	's	's	POS
cord-288231-vg8bwed9	107	11	postulates	postulate	VBZ
cord-288231-vg8bwed9	107	12	Direct	direct	JJ
cord-288231-vg8bwed9	107	13	evidence	evidence	NN
cord-288231-vg8bwed9	107	14	of	of	IN
cord-288231-vg8bwed9	107	15	extensive	extensive	JJ
cord-288231-vg8bwed9	107	16	diversity	diversity	NN
cord-288231-vg8bwed9	107	17	of	of	IN
cord-288231-vg8bwed9	107	18	HIV-1	HIV-1	NNP
cord-288231-vg8bwed9	107	19	in	in	IN
cord-288231-vg8bwed9	107	20	Kinshasa	Kinshasa	NNP
cord-288231-vg8bwed9	107	21	by	by	IN
cord-288231-vg8bwed9	107	22	1960	1960	CD
cord-288231-vg8bwed9	107	23	Transcriptional	Transcriptional	NNP
cord-288231-vg8bwed9	107	24	profiling	profiling	NN
cord-288231-vg8bwed9	107	25	in	in	IN
cord-288231-vg8bwed9	107	26	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	107	27	and	and	CC
cord-288231-vg8bwed9	107	28	non	non	JJ
cord-288231-vg8bwed9	107	29	-	-	JJ
cord-288231-vg8bwed9	107	30	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	107	31	SIV	SIV	NNP
cord-288231-vg8bwed9	107	32	infections	infection	NNS
cord-288231-vg8bwed9	107	33	reveals	reveal	VBZ
cord-288231-vg8bwed9	107	34	significant	significant	JJ
cord-288231-vg8bwed9	107	35	distinctions	distinction	NNS
cord-288231-vg8bwed9	107	36	in	in	IN
cord-288231-vg8bwed9	107	37	kinetics	kinetics	NN
cord-288231-vg8bwed9	107	38	and	and	CC
cord-288231-vg8bwed9	107	39	tissue	tissue	NN
cord-288231-vg8bwed9	107	40	compartmentalization	compartmentalization	NN
cord-288231-vg8bwed9	108	1	Divergent	divergent	JJ
cord-288231-vg8bwed9	108	2	TLR7	TLR7	NNP
cord-288231-vg8bwed9	108	3	and	and	CC
cord-288231-vg8bwed9	108	4	TLR9	TLR9	NNP
cord-288231-vg8bwed9	108	5	signaling	signaling	NN
cord-288231-vg8bwed9	108	6	and	and	CC
cord-288231-vg8bwed9	108	7	type	type	NN
cord-288231-vg8bwed9	109	1	I	-PRON-	PRP
cord-288231-vg8bwed9	109	2	interferon	interferon	VBD
cord-288231-vg8bwed9	109	3	production	production	NN
cord-288231-vg8bwed9	109	4	distinguish	distinguish	VBP
cord-288231-vg8bwed9	110	1	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	110	2	and	and	CC
cord-288231-vg8bwed9	110	3	nonpathogenic	nonpathogenic	NNP
cord-288231-vg8bwed9	110	4	AIDS	AIDS	NNP
cord-288231-vg8bwed9	110	5	virus	virus	NN
cord-288231-vg8bwed9	110	6	infections	infection	NNS
cord-288231-vg8bwed9	110	7	Spatial	spatial	JJ
cord-288231-vg8bwed9	110	8	,	,	,
cord-288231-vg8bwed9	110	9	temporal	temporal	JJ
cord-288231-vg8bwed9	110	10	,	,	,
cord-288231-vg8bwed9	110	11	and	and	CC
cord-288231-vg8bwed9	110	12	species	species	NN
cord-288231-vg8bwed9	110	13	variation	variation	NN
cord-288231-vg8bwed9	110	14	in	in	IN
cord-288231-vg8bwed9	110	15	prevalence	prevalence	NN
cord-288231-vg8bwed9	110	16	of	of	IN
cord-288231-vg8bwed9	110	17	influenza	influenza	NN
cord-288231-vg8bwed9	110	18	A	a	DT
cord-288231-vg8bwed9	110	19	viruses	virus	NNS
cord-288231-vg8bwed9	110	20	in	in	IN
cord-288231-vg8bwed9	110	21	wild	wild	JJ
cord-288231-vg8bwed9	110	22	migratory	migratory	JJ
cord-288231-vg8bwed9	110	23	birds	bird	NNS
cord-288231-vg8bwed9	111	1	Wild	wild	JJ
cord-288231-vg8bwed9	111	2	ducks	duck	NNS
cord-288231-vg8bwed9	111	3	as	as	IN
cord-288231-vg8bwed9	111	4	long	long	JJ
cord-288231-vg8bwed9	111	5	-	-	HYPH
cord-288231-vg8bwed9	111	6	distance	distance	NN
cord-288231-vg8bwed9	111	7	vectors	vector	NNS
cord-288231-vg8bwed9	111	8	of	of	IN
cord-288231-vg8bwed9	111	9	highly	highly	RB
cord-288231-vg8bwed9	111	10	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	111	11	avian	avian	JJ
cord-288231-vg8bwed9	111	12	influenza	influenza	NN
cord-288231-vg8bwed9	111	13	virus	virus	NN
cord-288231-vg8bwed9	111	14	(	(	-LRB-
cord-288231-vg8bwed9	111	15	H5N1	H5N1	NNP
cord-288231-vg8bwed9	111	16	)	)	-RRB-
cord-288231-vg8bwed9	112	1	Molecular	molecular	JJ
cord-288231-vg8bwed9	112	2	basis	basis	NN
cord-288231-vg8bwed9	112	3	for	for	IN
cord-288231-vg8bwed9	112	4	high	high	JJ
cord-288231-vg8bwed9	112	5	virulence	virulence	NN
cord-288231-vg8bwed9	112	6	of	of	IN
cord-288231-vg8bwed9	112	7	Hong	Hong	NNP
cord-288231-vg8bwed9	112	8	Kong	Kong	NNP
cord-288231-vg8bwed9	112	9	H5N1	H5N1	NNP
cord-288231-vg8bwed9	113	1	influenza	influenza	NN
cord-288231-vg8bwed9	113	2	A	a	DT
cord-288231-vg8bwed9	113	3	viruses	virus	NNS
cord-288231-vg8bwed9	113	4	H5N1	H5N1	NNP
cord-288231-vg8bwed9	113	5	virus	virus	NN
cord-288231-vg8bwed9	113	6	attachment	attachment	NN
cord-288231-vg8bwed9	113	7	to	to	TO
cord-288231-vg8bwed9	113	8	lower	lower	VB
cord-288231-vg8bwed9	113	9	respiratory	respiratory	JJ
cord-288231-vg8bwed9	113	10	tract	tract	NN
cord-288231-vg8bwed9	113	11	Haemagglutinin	Haemagglutinin	NNP
cord-288231-vg8bwed9	113	12	mutations	mutation	NNS
cord-288231-vg8bwed9	113	13	responsible	responsible	JJ
cord-288231-vg8bwed9	113	14	for	for	IN
cord-288231-vg8bwed9	113	15	the	the	DT
cord-288231-vg8bwed9	113	16	binding	binding	NN
cord-288231-vg8bwed9	113	17	of	of	IN
cord-288231-vg8bwed9	113	18	H5N1	H5N1	NNP
cord-288231-vg8bwed9	113	19	influenza	influenza	NN
cord-288231-vg8bwed9	113	20	A	a	DT
cord-288231-vg8bwed9	113	21	viruses	virus	NNS
cord-288231-vg8bwed9	113	22	to	to	IN
cord-288231-vg8bwed9	113	23	human	human	JJ
cord-288231-vg8bwed9	113	24	-	-	HYPH
cord-288231-vg8bwed9	113	25	type	type	NN
cord-288231-vg8bwed9	113	26	receptors	receptor	NNS
cord-288231-vg8bwed9	113	27	Mapping	map	VBG
cord-288231-vg8bwed9	113	28	the	the	DT
cord-288231-vg8bwed9	113	29	antigenic	antigenic	JJ
cord-288231-vg8bwed9	113	30	and	and	CC
cord-288231-vg8bwed9	113	31	genetic	genetic	JJ
cord-288231-vg8bwed9	113	32	evolution	evolution	NN
cord-288231-vg8bwed9	113	33	of	of	IN
cord-288231-vg8bwed9	113	34	influenza	influenza	NN
cord-288231-vg8bwed9	113	35	virus	virus	NN
cord-288231-vg8bwed9	113	36	Cellular	cellular	JJ
cord-288231-vg8bwed9	113	37	transcriptional	transcriptional	JJ
cord-288231-vg8bwed9	113	38	profiling	profiling	NN
cord-288231-vg8bwed9	113	39	in	in	IN
cord-288231-vg8bwed9	113	40	influenza	influenza	NN
cord-288231-vg8bwed9	113	41	A	a	DT
cord-288231-vg8bwed9	113	42	virus	virus	NN
cord-288231-vg8bwed9	113	43	-	-	HYPH
cord-288231-vg8bwed9	113	44	infected	infect	VBN
cord-288231-vg8bwed9	113	45	lung	lung	NN
cord-288231-vg8bwed9	113	46	epithelial	epithelial	NN
cord-288231-vg8bwed9	113	47	cells	cell	NNS
cord-288231-vg8bwed9	113	48	:	:	:
cord-288231-vg8bwed9	114	1	The	the	DT
cord-288231-vg8bwed9	114	2	role	role	NN
cord-288231-vg8bwed9	114	3	of	of	IN
cord-288231-vg8bwed9	114	4	the	the	DT
cord-288231-vg8bwed9	114	5	nonstructural	nonstructural	JJ
cord-288231-vg8bwed9	114	6	NS1	ns1	NN
cord-288231-vg8bwed9	114	7	protein	protein	NN
cord-288231-vg8bwed9	114	8	in	in	IN
cord-288231-vg8bwed9	114	9	the	the	DT
cord-288231-vg8bwed9	114	10	evasion	evasion	NN
cord-288231-vg8bwed9	114	11	of	of	IN
cord-288231-vg8bwed9	114	12	the	the	DT
cord-288231-vg8bwed9	114	13	host	host	NN
cord-288231-vg8bwed9	114	14	innate	innate	JJ
cord-288231-vg8bwed9	114	15	defense	defense	NN
cord-288231-vg8bwed9	114	16	and	and	CC
cord-288231-vg8bwed9	114	17	its	-PRON-	PRP$
cord-288231-vg8bwed9	114	18	potential	potential	JJ
cord-288231-vg8bwed9	114	19	contribution	contribution	NN
cord-288231-vg8bwed9	114	20	to	to	IN
cord-288231-vg8bwed9	114	21	pandemic	pandemic	NN
cord-288231-vg8bwed9	114	22	influenza	influenza	NN
cord-288231-vg8bwed9	114	23	Aberrant	aberrant	JJ
cord-288231-vg8bwed9	114	24	innate	innate	JJ
cord-288231-vg8bwed9	114	25	immune	immune	JJ
cord-288231-vg8bwed9	114	26	response	response	NN
cord-288231-vg8bwed9	114	27	in	in	IN
cord-288231-vg8bwed9	114	28	lethal	lethal	JJ
cord-288231-vg8bwed9	114	29	infection	infection	NN
cord-288231-vg8bwed9	114	30	of	of	IN
cord-288231-vg8bwed9	114	31	macaques	macaque	NNS
cord-288231-vg8bwed9	114	32	with	with	IN
cord-288231-vg8bwed9	114	33	the	the	DT
cord-288231-vg8bwed9	114	34	1918	1918	CD
cord-288231-vg8bwed9	114	35	influenza	influenza	NN
cord-288231-vg8bwed9	114	36	virus	virus	NN
cord-288231-vg8bwed9	114	37	Early	early	RB
cord-288231-vg8bwed9	114	38	and	and	CC
cord-288231-vg8bwed9	114	39	sustained	sustain	VBD
cord-288231-vg8bwed9	114	40	innate	innate	JJ
cord-288231-vg8bwed9	114	41	immune	immune	JJ
cord-288231-vg8bwed9	114	42	response	response	NN
cord-288231-vg8bwed9	114	43	defines	define	VBZ
cord-288231-vg8bwed9	114	44	pathology	pathology	NN
cord-288231-vg8bwed9	114	45	and	and	CC
cord-288231-vg8bwed9	114	46	death	death	NN
cord-288231-vg8bwed9	114	47	in	in	IN
cord-288231-vg8bwed9	114	48	nonhuman	nonhuman	NN
cord-288231-vg8bwed9	114	49	primates	primate	NNS
cord-288231-vg8bwed9	114	50	infected	infect	VBN
cord-288231-vg8bwed9	114	51	by	by	IN
cord-288231-vg8bwed9	114	52	highly	highly	RB
cord-288231-vg8bwed9	114	53	pathogenic	pathogenic	JJ
cord-288231-vg8bwed9	114	54	influenza	influenza	NN
cord-288231-vg8bwed9	114	55	virus	virus	NN
cord-288231-vg8bwed9	114	56	Genomic	genomic	JJ
cord-288231-vg8bwed9	114	57	analysis	analysis	NN
cord-288231-vg8bwed9	114	58	of	of	IN
cord-288231-vg8bwed9	114	59	increased	increase	VBN
cord-288231-vg8bwed9	114	60	host	host	NN
cord-288231-vg8bwed9	114	61	immune	immune	NN
cord-288231-vg8bwed9	114	62	and	and	CC
cord-288231-vg8bwed9	114	63	cell	cell	NN
cord-288231-vg8bwed9	114	64	death	death	NN
cord-288231-vg8bwed9	114	65	responses	response	NNS
cord-288231-vg8bwed9	114	66	induced	induce	VBN
cord-288231-vg8bwed9	114	67	by	by	IN
cord-288231-vg8bwed9	114	68	1918	1918	CD
cord-288231-vg8bwed9	114	69	influenza	influenza	NN
cord-288231-vg8bwed9	114	70	virus	virus	NN
cord-288231-vg8bwed9	114	71	Global	global	JJ
cord-288231-vg8bwed9	114	72	host	host	NN
cord-288231-vg8bwed9	114	73	immune	immune	JJ
cord-288231-vg8bwed9	114	74	response	response	NN
cord-288231-vg8bwed9	114	75	:	:	:
cord-288231-vg8bwed9	114	76	Pathogenesis	pathogenesis	NN
cord-288231-vg8bwed9	114	77	and	and	CC
cord-288231-vg8bwed9	114	78	transcriptional	transcriptional	JJ
cord-288231-vg8bwed9	114	79	profiling	profiling	NN
cord-288231-vg8bwed9	114	80	of	of	IN
cord-288231-vg8bwed9	114	81	type	type	NN
cord-288231-vg8bwed9	114	82	A	a	DT
cord-288231-vg8bwed9	114	83	influenza	influenza	NN
cord-288231-vg8bwed9	114	84	viruses	virus	NNS
cord-288231-vg8bwed9	114	85	expressing	express	VBG
cord-288231-vg8bwed9	114	86	the	the	DT
cord-288231-vg8bwed9	114	87	hemagglutinin	hemagglutinin	NN
cord-288231-vg8bwed9	114	88	and	and	CC
cord-288231-vg8bwed9	114	89	neuraminidase	neuraminidase	NN
cord-288231-vg8bwed9	114	90	genes	gene	NNS
cord-288231-vg8bwed9	114	91	from	from	IN
cord-288231-vg8bwed9	114	92	the	the	DT
cord-288231-vg8bwed9	114	93	1918	1918	CD
cord-288231-vg8bwed9	114	94	pandemic	pandemic	NN
cord-288231-vg8bwed9	114	95	virus	virus	NN
cord-288231-vg8bwed9	114	96	Gene	Gene	NNP
cord-288231-vg8bwed9	114	97	expression	expression	NN
cord-288231-vg8bwed9	114	98	analysis	analysis	NN
cord-288231-vg8bwed9	114	99	of	of	IN
cord-288231-vg8bwed9	114	100	host	host	NN
cord-288231-vg8bwed9	114	101	innate	innate	JJ
cord-288231-vg8bwed9	114	102	immune	immune	JJ
cord-288231-vg8bwed9	114	103	responses	response	NNS
cord-288231-vg8bwed9	114	104	during	during	IN
cord-288231-vg8bwed9	114	105	lethal	lethal	JJ
cord-288231-vg8bwed9	114	106	H5N1	H5N1	NNP
cord-288231-vg8bwed9	114	107	infection	infection	NN
cord-288231-vg8bwed9	114	108	in	in	IN
cord-288231-vg8bwed9	114	109	ferrets	ferret	NNS
cord-288231-vg8bwed9	114	110	The	the	DT
cord-288231-vg8bwed9	114	111	role	role	NN
cord-288231-vg8bwed9	114	112	of	of	IN
cord-288231-vg8bwed9	114	113	genomics	genomic	NNS
cord-288231-vg8bwed9	114	114	in	in	IN
cord-288231-vg8bwed9	114	115	tracking	track	VBG
cord-288231-vg8bwed9	114	116	the	the	DT
cord-288231-vg8bwed9	114	117	evolution	evolution	NN
cord-288231-vg8bwed9	114	118	of	of	IN
cord-288231-vg8bwed9	114	119	influenza	influenza	NN
cord-288231-vg8bwed9	114	120	A	a	DT
cord-288231-vg8bwed9	114	121	virus	virus	NN
cord-288231-vg8bwed9	114	122	Prevalence	prevalence	NN
cord-288231-vg8bwed9	114	123	and	and	CC
cord-288231-vg8bwed9	114	124	genetic	genetic	JJ
cord-288231-vg8bwed9	114	125	diversity	diversity	NN
cord-288231-vg8bwed9	114	126	of	of	IN
cord-288231-vg8bwed9	114	127	coronaviruses	coronaviruse	NNS
cord-288231-vg8bwed9	114	128	in	in	IN
cord-288231-vg8bwed9	114	129	bats	bat	NNS
cord-288231-vg8bwed9	114	130	from	from	IN
cord-288231-vg8bwed9	114	131	China	China	NNP
cord-288231-vg8bwed9	114	132	Cross	Cross	NNP
cord-288231-vg8bwed9	114	133	-	-	JJ
cord-288231-vg8bwed9	114	134	host	host	JJ
cord-288231-vg8bwed9	114	135	evolution	evolution	NN
cord-288231-vg8bwed9	114	136	of	of	IN
cord-288231-vg8bwed9	114	137	severe	severe	JJ
cord-288231-vg8bwed9	114	138	acute	acute	JJ
cord-288231-vg8bwed9	114	139	respiratory	respiratory	JJ
cord-288231-vg8bwed9	114	140	syndrome	syndrome	NN
cord-288231-vg8bwed9	114	141	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	114	142	in	in	IN
cord-288231-vg8bwed9	114	143	palm	palm	NN
cord-288231-vg8bwed9	114	144	civet	civet	NN
cord-288231-vg8bwed9	114	145	and	and	CC
cord-288231-vg8bwed9	114	146	human	human	JJ
cord-288231-vg8bwed9	114	147	Receptor	receptor	NN
cord-288231-vg8bwed9	114	148	and	and	CC
cord-288231-vg8bwed9	114	149	viral	viral	JJ
cord-288231-vg8bwed9	114	150	determinants	determinant	NNS
cord-288231-vg8bwed9	114	151	of	of	IN
cord-288231-vg8bwed9	114	152	SARS	SARS	NNP
cord-288231-vg8bwed9	114	153	-	-	HYPH
cord-288231-vg8bwed9	114	154	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	114	155	adaptation	adaptation	NN
cord-288231-vg8bwed9	114	156	to	to	IN
cord-288231-vg8bwed9	114	157	human	human	JJ
cord-288231-vg8bwed9	114	158	ACE2	ACE2	NNP
cord-288231-vg8bwed9	114	159	Mechanisms	Mechanisms	NNPS
cord-288231-vg8bwed9	114	160	of	of	IN
cord-288231-vg8bwed9	114	161	zoonotic	zoonotic	JJ
cord-288231-vg8bwed9	114	162	severe	severe	JJ
cord-288231-vg8bwed9	114	163	acute	acute	JJ
cord-288231-vg8bwed9	114	164	respiratory	respiratory	JJ
cord-288231-vg8bwed9	114	165	syndrome	syndrome	NN
cord-288231-vg8bwed9	114	166	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	114	167	host	host	NN
cord-288231-vg8bwed9	114	168	range	range	NN
cord-288231-vg8bwed9	114	169	expansion	expansion	NN
cord-288231-vg8bwed9	114	170	in	in	IN
cord-288231-vg8bwed9	114	171	human	human	JJ
cord-288231-vg8bwed9	114	172	airway	airway	NN
cord-288231-vg8bwed9	114	173	epithelium	epithelium	NN
cord-288231-vg8bwed9	114	174	Early	early	JJ
cord-288231-vg8bwed9	114	175	upregulation	upregulation	NN
cord-288231-vg8bwed9	114	176	of	of	IN
cord-288231-vg8bwed9	114	177	acute	acute	JJ
cord-288231-vg8bwed9	114	178	respiratory	respiratory	JJ
cord-288231-vg8bwed9	114	179	distress	distress	NN
cord-288231-vg8bwed9	114	180	syndrome	syndrome	NN
cord-288231-vg8bwed9	114	181	-	-	HYPH
cord-288231-vg8bwed9	114	182	associated	associate	VBN
cord-288231-vg8bwed9	114	183	cytokines	cytokine	NNS
cord-288231-vg8bwed9	114	184	promotes	promote	VBZ
cord-288231-vg8bwed9	114	185	lethal	lethal	JJ
cord-288231-vg8bwed9	114	186	disease	disease	NN
cord-288231-vg8bwed9	114	187	in	in	IN
cord-288231-vg8bwed9	114	188	an	an	DT
cord-288231-vg8bwed9	114	189	aged	aged	JJ
cord-288231-vg8bwed9	114	190	-	-	HYPH
cord-288231-vg8bwed9	114	191	mouse	mouse	NN
cord-288231-vg8bwed9	114	192	model	model	NN
cord-288231-vg8bwed9	114	193	of	of	IN
cord-288231-vg8bwed9	114	194	severe	severe	JJ
cord-288231-vg8bwed9	114	195	acute	acute	JJ
cord-288231-vg8bwed9	114	196	respiratory	respiratory	JJ
cord-288231-vg8bwed9	114	197	syndrome	syndrome	NN
cord-288231-vg8bwed9	114	198	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	114	199	infection	infection	NN
cord-288231-vg8bwed9	114	200	Functional	functional	JJ
cord-288231-vg8bwed9	114	201	genomics	genomic	NNS
cord-288231-vg8bwed9	114	202	highlights	highlight	VBZ
cord-288231-vg8bwed9	114	203	differential	differential	JJ
cord-288231-vg8bwed9	114	204	induction	induction	NN
cord-288231-vg8bwed9	114	205	of	of	IN
cord-288231-vg8bwed9	114	206	antiviral	antiviral	JJ
cord-288231-vg8bwed9	114	207	pathways	pathway	NNS
cord-288231-vg8bwed9	114	208	in	in	IN
cord-288231-vg8bwed9	114	209	the	the	DT
cord-288231-vg8bwed9	114	210	lungs	lung	NNS
cord-288231-vg8bwed9	114	211	of	of	IN
cord-288231-vg8bwed9	114	212	SARS	SARS	NNP
cord-288231-vg8bwed9	114	213	-	-	HYPH
cord-288231-vg8bwed9	114	214	CoV	CoV	NNP
cord-288231-vg8bwed9	114	215	-	-	HYPH
cord-288231-vg8bwed9	114	216	infected	infect	VBN
cord-288231-vg8bwed9	114	217	macaques	macaque	NNS
cord-288231-vg8bwed9	115	1	Genomic	genomic	JJ
cord-288231-vg8bwed9	115	2	analysis	analysis	NN
cord-288231-vg8bwed9	115	3	reveals	reveal	VBZ
cord-288231-vg8bwed9	115	4	age	age	NN
cord-288231-vg8bwed9	115	5	-	-	HYPH
cord-288231-vg8bwed9	115	6	dependent	dependent	JJ
cord-288231-vg8bwed9	115	7	innate	innate	JJ
cord-288231-vg8bwed9	115	8	immune	immune	JJ
cord-288231-vg8bwed9	115	9	responses	response	NNS
cord-288231-vg8bwed9	115	10	to	to	IN
cord-288231-vg8bwed9	116	1	severe	severe	JJ
cord-288231-vg8bwed9	116	2	acute	acute	JJ
cord-288231-vg8bwed9	116	3	respiratory	respiratory	JJ
cord-288231-vg8bwed9	116	4	syndrome	syndrome	NN
cord-288231-vg8bwed9	116	5	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	116	6	Pegylated	Pegylated	NNP
cord-288231-vg8bwed9	116	7	interferon	interferon	NN
cord-288231-vg8bwed9	116	8	-	-	HYPH
cord-288231-vg8bwed9	116	9	alpha	alpha	NN
cord-288231-vg8bwed9	116	10	protects	protect	VBZ
cord-288231-vg8bwed9	116	11	type	type	NN
cord-288231-vg8bwed9	116	12	1	1	CD
cord-288231-vg8bwed9	116	13	pneumocytes	pneumocyte	NNS
cord-288231-vg8bwed9	116	14	against	against	IN
cord-288231-vg8bwed9	116	15	SARS	SARS	NNP
cord-288231-vg8bwed9	116	16	coronavirus	coronavirus	NN
cord-288231-vg8bwed9	116	17	infection	infection	NN
cord-288231-vg8bwed9	116	18	in	in	IN
cord-288231-vg8bwed9	116	19	macaques	macaque	NNS
cord-288231-vg8bwed9	116	20	Virogenomics	Virogenomics	NNP
cord-288231-vg8bwed9	116	21	:	:	:
cord-288231-vg8bwed9	117	1	The	the	DT
cord-288231-vg8bwed9	117	2	virus	virus	NN
cord-288231-vg8bwed9	117	3	-host	-host	NN
cord-288231-vg8bwed9	117	4	interaction	interaction	NN
cord-288231-vg8bwed9	117	5	revisited	revisit	VBN