id	sid	tid	token	lemma	pos
cord-264532-xfb94lq8	1	1	key	key	JJ
cord-264532-xfb94lq8	1	2	:	:	:
cord-264532-xfb94lq8	1	3	cord-264532-xfb94lq8	cord-264532-xfb94lq8	NN
cord-264532-xfb94lq8	1	4	authors	author	NNS
cord-264532-xfb94lq8	1	5	:	:	:
cord-264532-xfb94lq8	1	6	Bull	Bull	NNP
cord-264532-xfb94lq8	1	7	,	,	,
cord-264532-xfb94lq8	1	8	James	James	NNP
cord-264532-xfb94lq8	1	9	J	J	NNP
cord-264532-xfb94lq8	1	10	;	;	:
cord-264532-xfb94lq8	1	11	Ebert	Ebert	NNP
cord-264532-xfb94lq8	1	12	,	,	,
cord-264532-xfb94lq8	1	13	Dieter	Dieter	NNP
cord-264532-xfb94lq8	1	14	title	title	NN
cord-264532-xfb94lq8	1	15	:	:	:
cord-264532-xfb94lq8	1	16	Invasion	invasion	NN
cord-264532-xfb94lq8	1	17	thresholds	threshold	NNS
cord-264532-xfb94lq8	1	18	and	and	CC
cord-264532-xfb94lq8	1	19	the	the	DT
cord-264532-xfb94lq8	1	20	evolution	evolution	NN
cord-264532-xfb94lq8	1	21	of	of	IN
cord-264532-xfb94lq8	1	22	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	1	23	virulence	virulence	NN
cord-264532-xfb94lq8	1	24	date	date	NN
cord-264532-xfb94lq8	1	25	:	:	:
cord-264532-xfb94lq8	1	26	2008	2008	CD
cord-264532-xfb94lq8	1	27	-	-	SYM
cord-264532-xfb94lq8	1	28	01	01	CD
cord-264532-xfb94lq8	1	29	-	-	HYPH
cord-264532-xfb94lq8	1	30	09	09	CD
cord-264532-xfb94lq8	1	31	journal	journal	NN
cord-264532-xfb94lq8	1	32	:	:	:
cord-264532-xfb94lq8	2	1	Evol	Evol	NNP
cord-264532-xfb94lq8	2	2	Appl	Appl	NNP
cord-264532-xfb94lq8	2	3	DOI	DOI	NNP
cord-264532-xfb94lq8	2	4	:	:	:
cord-264532-xfb94lq8	2	5	10.1111	10.1111	CD
cord-264532-xfb94lq8	2	6	/	/	SYM
cord-264532-xfb94lq8	2	7	j.1752	j.1752	NNP
cord-264532-xfb94lq8	2	8	-	-	HYPH
cord-264532-xfb94lq8	2	9	4571.2007.00003.x	4571.2007.00003.x	CD
cord-264532-xfb94lq8	2	10	sha	sha	NNP
cord-264532-xfb94lq8	2	11	:	:	:
cord-264532-xfb94lq8	3	1	d086f62864fb6b39416bad3b5a969668b1791acb	d086f62864fb6b39416bad3b5a969668b1791acb	NNP
cord-264532-xfb94lq8	3	2	doc_id	doc_id	NNP
cord-264532-xfb94lq8	3	3	:	:	:
cord-264532-xfb94lq8	3	4	264532	264532	CD
cord-264532-xfb94lq8	3	5	cord_uid	cord_uid	NNS
cord-264532-xfb94lq8	3	6	:	:	:
cord-264532-xfb94lq8	4	1	xfb94lq8	xfb94lq8	NNP
cord-264532-xfb94lq8	5	1	The	the	DT
cord-264532-xfb94lq8	5	2	enterprise	enterprise	NN
cord-264532-xfb94lq8	5	3	of	of	IN
cord-264532-xfb94lq8	5	4	virulence	virulence	NN
cord-264532-xfb94lq8	5	5	management	management	NN
cord-264532-xfb94lq8	5	6	attempts	attempt	NNS
cord-264532-xfb94lq8	5	7	to	to	TO
cord-264532-xfb94lq8	5	8	predict	predict	VB
cord-264532-xfb94lq8	5	9	how	how	WRB
cord-264532-xfb94lq8	5	10	social	social	JJ
cord-264532-xfb94lq8	5	11	practices	practice	NNS
cord-264532-xfb94lq8	5	12	and	and	CC
cord-264532-xfb94lq8	5	13	other	other	JJ
cord-264532-xfb94lq8	5	14	factors	factor	NNS
cord-264532-xfb94lq8	5	15	affect	affect	VBP
cord-264532-xfb94lq8	5	16	the	the	DT
cord-264532-xfb94lq8	5	17	evolution	evolution	NN
cord-264532-xfb94lq8	5	18	of	of	IN
cord-264532-xfb94lq8	5	19	parasite	parasite	NN
cord-264532-xfb94lq8	5	20	virulence	virulence	NN
cord-264532-xfb94lq8	5	21	.	.	.
cord-264532-xfb94lq8	6	1	These	these	DT
cord-264532-xfb94lq8	6	2	predictions	prediction	NNS
cord-264532-xfb94lq8	6	3	are	be	VBP
cord-264532-xfb94lq8	6	4	often	often	RB
cord-264532-xfb94lq8	6	5	based	base	VBN
cord-264532-xfb94lq8	6	6	on	on	IN
cord-264532-xfb94lq8	6	7	parasite	parasite	NN
cord-264532-xfb94lq8	6	8	optima	optima	NNP
cord-264532-xfb94lq8	6	9	or	or	CC
cord-264532-xfb94lq8	6	10	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	6	11	equilibria	equilibrium	NNS
cord-264532-xfb94lq8	6	12	derived	derive	VBN
cord-264532-xfb94lq8	6	13	from	from	IN
cord-264532-xfb94lq8	6	14	models	model	NNS
cord-264532-xfb94lq8	6	15	of	of	IN
cord-264532-xfb94lq8	6	16	host	host	NN
cord-264532-xfb94lq8	6	17	-	-	HYPH
cord-264532-xfb94lq8	6	18	parasite	parasite	NN
cord-264532-xfb94lq8	6	19	dynamics	dynamic	NNS
cord-264532-xfb94lq8	6	20	.	.	.
cord-264532-xfb94lq8	7	1	Yet	yet	CC
cord-264532-xfb94lq8	7	2	even	even	RB
cord-264532-xfb94lq8	7	3	when	when	WRB
cord-264532-xfb94lq8	7	4	such	such	JJ
cord-264532-xfb94lq8	7	5	models	model	NNS
cord-264532-xfb94lq8	7	6	accurately	accurately	RB
cord-264532-xfb94lq8	7	7	capture	capture	VBP
cord-264532-xfb94lq8	7	8	the	the	DT
cord-264532-xfb94lq8	7	9	parasite	parasite	NN
cord-264532-xfb94lq8	7	10	optima	optima	NNP
cord-264532-xfb94lq8	7	11	,	,	,
cord-264532-xfb94lq8	7	12	newly	newly	RB
cord-264532-xfb94lq8	7	13	invading	invade	VBG
cord-264532-xfb94lq8	7	14	parasites	parasite	NNS
cord-264532-xfb94lq8	7	15	will	will	MD
cord-264532-xfb94lq8	7	16	typically	typically	RB
cord-264532-xfb94lq8	7	17	not	not	RB
cord-264532-xfb94lq8	7	18	be	be	VB
cord-264532-xfb94lq8	7	19	at	at	IN
cord-264532-xfb94lq8	7	20	their	-PRON-	PRP$
cord-264532-xfb94lq8	7	21	optima	optima	NNP
cord-264532-xfb94lq8	7	22	.	.	.
cord-264532-xfb94lq8	8	1	Here	here	RB
cord-264532-xfb94lq8	8	2	we	-PRON-	PRP
cord-264532-xfb94lq8	8	3	show	show	VBP
cord-264532-xfb94lq8	8	4	that	that	IN
cord-264532-xfb94lq8	8	5	parasite	parasite	JJ
cord-264532-xfb94lq8	8	6	invasion	invasion	NN
cord-264532-xfb94lq8	8	7	of	of	IN
cord-264532-xfb94lq8	8	8	a	a	DT
cord-264532-xfb94lq8	8	9	host	host	NN
cord-264532-xfb94lq8	8	10	population	population	NN
cord-264532-xfb94lq8	8	11	can	can	MD
cord-264532-xfb94lq8	8	12	occur	occur	VB
cord-264532-xfb94lq8	8	13	despite	despite	IN
cord-264532-xfb94lq8	8	14	highly	highly	RB
cord-264532-xfb94lq8	8	15	nonoptimal	nonoptimal	JJ
cord-264532-xfb94lq8	8	16	virulence	virulence	NN
cord-264532-xfb94lq8	8	17	.	.	.
cord-264532-xfb94lq8	9	1	Fitness	fitness	NN
cord-264532-xfb94lq8	9	2	improvements	improvement	NNS
cord-264532-xfb94lq8	9	3	soon	soon	RB
cord-264532-xfb94lq8	9	4	after	after	IN
cord-264532-xfb94lq8	9	5	invasion	invasion	NN
cord-264532-xfb94lq8	9	6	may	may	MD
cord-264532-xfb94lq8	9	7	proceed	proceed	VB
cord-264532-xfb94lq8	9	8	through	through	IN
cord-264532-xfb94lq8	9	9	many	many	JJ
cord-264532-xfb94lq8	9	10	steps	step	NNS
cord-264532-xfb94lq8	9	11	with	with	IN
cord-264532-xfb94lq8	9	12	wide	wide	JJ
cord-264532-xfb94lq8	9	13	changes	change	NNS
cord-264532-xfb94lq8	9	14	in	in	IN
cord-264532-xfb94lq8	9	15	virulence	virulence	NN
cord-264532-xfb94lq8	9	16	,	,	,
cord-264532-xfb94lq8	9	17	because	because	IN
cord-264532-xfb94lq8	9	18	fitness	fitness	NN
cord-264532-xfb94lq8	9	19	depends	depend	VBZ
cord-264532-xfb94lq8	9	20	on	on	IN
cord-264532-xfb94lq8	9	21	transmission	transmission	NN
cord-264532-xfb94lq8	9	22	as	as	RB
cord-264532-xfb94lq8	9	23	well	well	RB
cord-264532-xfb94lq8	9	24	as	as	IN
cord-264532-xfb94lq8	9	25	virulence	virulence	NN
cord-264532-xfb94lq8	9	26	,	,	,
cord-264532-xfb94lq8	9	27	and	and	CC
cord-264532-xfb94lq8	9	28	transmission	transmission	NN
cord-264532-xfb94lq8	9	29	improvements	improvement	NNS
cord-264532-xfb94lq8	9	30	can	can	MD
cord-264532-xfb94lq8	9	31	overwhelm	overwhelm	VB
cord-264532-xfb94lq8	9	32	nonoptimal	nonoptimal	JJ
cord-264532-xfb94lq8	9	33	virulence	virulence	NN
cord-264532-xfb94lq8	9	34	.	.	.
cord-264532-xfb94lq8	10	1	This	this	DT
cord-264532-xfb94lq8	10	2	process	process	NN
cord-264532-xfb94lq8	10	3	is	be	VBZ
cord-264532-xfb94lq8	10	4	highly	highly	RB
cord-264532-xfb94lq8	10	5	sensitive	sensitive	JJ
cord-264532-xfb94lq8	10	6	to	to	IN
cord-264532-xfb94lq8	10	7	mutation	mutation	NN
cord-264532-xfb94lq8	10	8	supply	supply	NN
cord-264532-xfb94lq8	10	9	and	and	CC
cord-264532-xfb94lq8	10	10	the	the	DT
cord-264532-xfb94lq8	10	11	strength	strength	NN
cord-264532-xfb94lq8	10	12	of	of	IN
cord-264532-xfb94lq8	10	13	selection	selection	NN
cord-264532-xfb94lq8	10	14	.	.	.
cord-264532-xfb94lq8	11	1	Importantly	importantly	RB
cord-264532-xfb94lq8	11	2	,	,	,
cord-264532-xfb94lq8	11	3	the	the	DT
cord-264532-xfb94lq8	11	4	same	same	JJ
cord-264532-xfb94lq8	11	5	invasion	invasion	NN
cord-264532-xfb94lq8	11	6	principle	principle	NN
cord-264532-xfb94lq8	11	7	applies	apply	VBZ
cord-264532-xfb94lq8	11	8	to	to	IN
cord-264532-xfb94lq8	11	9	the	the	DT
cord-264532-xfb94lq8	11	10	evolution	evolution	NN
cord-264532-xfb94lq8	11	11	of	of	IN
cord-264532-xfb94lq8	11	12	established	establish	VBN
cord-264532-xfb94lq8	11	13	parasites	parasite	NNS
cord-264532-xfb94lq8	11	14	,	,	,
cord-264532-xfb94lq8	11	15	whenever	whenever	WRB
cord-264532-xfb94lq8	11	16	mutants	mutant	NNS
cord-264532-xfb94lq8	11	17	arise	arise	VBP
cord-264532-xfb94lq8	11	18	that	that	WDT
cord-264532-xfb94lq8	11	19	overcome	overcome	VBP
cord-264532-xfb94lq8	11	20	host	host	NN
cord-264532-xfb94lq8	11	21	immunity	immunity	NN
cord-264532-xfb94lq8	11	22	/	/	SYM
cord-264532-xfb94lq8	11	23	resistance	resistance	NN
cord-264532-xfb94lq8	11	24	.	.	.
cord-264532-xfb94lq8	12	1	A	a	DT
cord-264532-xfb94lq8	12	2	host	host	NN
cord-264532-xfb94lq8	12	3	population	population	NN
cord-264532-xfb94lq8	12	4	may	may	MD
cord-264532-xfb94lq8	12	5	consequently	consequently	RB
cord-264532-xfb94lq8	12	6	experience	experience	VB
cord-264532-xfb94lq8	12	7	repeated	repeat	VBN
cord-264532-xfb94lq8	12	8	invasions	invasion	NNS
cord-264532-xfb94lq8	12	9	of	of	IN
cord-264532-xfb94lq8	12	10	new	new	JJ
cord-264532-xfb94lq8	12	11	parasite	parasite	NN
cord-264532-xfb94lq8	12	12	variants	variant	NNS
cord-264532-xfb94lq8	12	13	and	and	CC
cord-264532-xfb94lq8	12	14	possible	possible	JJ
cord-264532-xfb94lq8	12	15	large	large	JJ
cord-264532-xfb94lq8	12	16	shifts	shift	NNS
cord-264532-xfb94lq8	12	17	in	in	IN
cord-264532-xfb94lq8	12	18	virulence	virulence	NN
cord-264532-xfb94lq8	12	19	as	as	IN
cord-264532-xfb94lq8	12	20	it	-PRON-	PRP
cord-264532-xfb94lq8	12	21	evolves	evolve	VBZ
cord-264532-xfb94lq8	12	22	in	in	IN
cord-264532-xfb94lq8	12	23	an	an	DT
cord-264532-xfb94lq8	12	24	arms	arm	NNS
cord-264532-xfb94lq8	12	25	race	race	NN
cord-264532-xfb94lq8	12	26	with	with	IN
cord-264532-xfb94lq8	12	27	the	the	DT
cord-264532-xfb94lq8	12	28	parasite	parasite	NN
cord-264532-xfb94lq8	12	29	.	.	.
cord-264532-xfb94lq8	13	1	An	an	DT
cord-264532-xfb94lq8	13	2	experimental	experimental	JJ
cord-264532-xfb94lq8	13	3	study	study	NN
cord-264532-xfb94lq8	13	4	of	of	IN
cord-264532-xfb94lq8	13	5	phage	phage	NN
cord-264532-xfb94lq8	13	6	lysis	lysis	NN
cord-264532-xfb94lq8	13	7	time	time	NN
cord-264532-xfb94lq8	13	8	and	and	CC
cord-264532-xfb94lq8	13	9	examples	example	NNS
cord-264532-xfb94lq8	13	10	of	of	IN
cord-264532-xfb94lq8	13	11	mammalian	mammalian	JJ
cord-264532-xfb94lq8	13	12	viruses	virus	NNS
cord-264532-xfb94lq8	13	13	matching	match	VBG
cord-264532-xfb94lq8	13	14	some	some	DT
cord-264532-xfb94lq8	13	15	of	of	IN
cord-264532-xfb94lq8	13	16	these	these	DT
cord-264532-xfb94lq8	13	17	characteristics	characteristic	NNS
cord-264532-xfb94lq8	13	18	are	be	VBP
cord-264532-xfb94lq8	13	19	reviewed	review	VBN
cord-264532-xfb94lq8	13	20	.	.	.
cord-264532-xfb94lq8	14	1	Virulence	virulence	NN
cord-264532-xfb94lq8	14	2	management	management	NN
cord-264532-xfb94lq8	14	3	is	be	VBZ
cord-264532-xfb94lq8	14	4	a	a	DT
cord-264532-xfb94lq8	14	5	modern	modern	JJ
cord-264532-xfb94lq8	14	6	field	field	NN
cord-264532-xfb94lq8	14	7	whose	whose	WP$
cord-264532-xfb94lq8	14	8	goal	goal	NN
cord-264532-xfb94lq8	14	9	is	be	VBZ
cord-264532-xfb94lq8	14	10	to	to	TO
cord-264532-xfb94lq8	14	11	predict	predict	VB
cord-264532-xfb94lq8	14	12	the	the	DT
cord-264532-xfb94lq8	14	13	consequences	consequence	NNS
cord-264532-xfb94lq8	14	14	of	of	IN
cord-264532-xfb94lq8	14	15	social	social	JJ
cord-264532-xfb94lq8	14	16	practices	practice	NNS
cord-264532-xfb94lq8	14	17	on	on	IN
cord-264532-xfb94lq8	14	18	the	the	DT
cord-264532-xfb94lq8	14	19	evolution	evolution	NN
cord-264532-xfb94lq8	14	20	of	of	IN
cord-264532-xfb94lq8	14	21	parasite	parasite	NN
cord-264532-xfb94lq8	14	22	virulence	virulence	NN
cord-264532-xfb94lq8	14	23	.	.	.
cord-264532-xfb94lq8	15	1	By	by	IN
cord-264532-xfb94lq8	15	2	understanding	understand	VBG
cord-264532-xfb94lq8	15	3	how	how	WRB
cord-264532-xfb94lq8	15	4	virulence	virulence	NN
cord-264532-xfb94lq8	15	5	is	be	VBZ
cord-264532-xfb94lq8	15	6	expected	expect	VBN
cord-264532-xfb94lq8	15	7	to	to	TO
cord-264532-xfb94lq8	15	8	evolve	evolve	VB
cord-264532-xfb94lq8	15	9	,	,	,
cord-264532-xfb94lq8	15	10	it	-PRON-	PRP
cord-264532-xfb94lq8	15	11	may	may	MD
cord-264532-xfb94lq8	15	12	be	be	VB
cord-264532-xfb94lq8	15	13	possible	possible	JJ
cord-264532-xfb94lq8	15	14	to	to	TO
cord-264532-xfb94lq8	15	15	encourage	encourage	VB
cord-264532-xfb94lq8	15	16	social	social	JJ
cord-264532-xfb94lq8	15	17	practices	practice	NNS
cord-264532-xfb94lq8	15	18	that	that	WDT
cord-264532-xfb94lq8	15	19	indirectly	indirectly	RB
cord-264532-xfb94lq8	15	20	select	select	VBP
cord-264532-xfb94lq8	15	21	lower	low	JJR
cord-264532-xfb94lq8	15	22	virulence	virulence	NN
cord-264532-xfb94lq8	15	23	.	.	.
cord-264532-xfb94lq8	16	1	Of	of	IN
cord-264532-xfb94lq8	16	2	special	special	JJ
cord-264532-xfb94lq8	16	3	concern	concern	NN
cord-264532-xfb94lq8	16	4	in	in	IN
cord-264532-xfb94lq8	16	5	virulence	virulence	NN
cord-264532-xfb94lq8	16	6	management	management	NN
cord-264532-xfb94lq8	16	7	are	be	VBP
cord-264532-xfb94lq8	16	8	environments	environment	NNS
cord-264532-xfb94lq8	16	9	that	that	WDT
cord-264532-xfb94lq8	16	10	might	may	MD
cord-264532-xfb94lq8	16	11	favor	favor	VB
cord-264532-xfb94lq8	16	12	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	16	13	increases	increase	NNS
cord-264532-xfb94lq8	16	14	in	in	IN
cord-264532-xfb94lq8	16	15	virulence	virulence	NN
cord-264532-xfb94lq8	16	16	,	,	,
cord-264532-xfb94lq8	16	17	such	such	JJ
cord-264532-xfb94lq8	16	18	as	as	IN
cord-264532-xfb94lq8	16	19	leaky	leaky	JJ
cord-264532-xfb94lq8	16	20	vaccines	vaccine	NNS
cord-264532-xfb94lq8	16	21	and	and	CC
cord-264532-xfb94lq8	16	22	high	high	JJ
cord-264532-xfb94lq8	16	23	host	host	NN
cord-264532-xfb94lq8	16	24	densities	density	NNS
cord-264532-xfb94lq8	16	25	(	(	-LRB-
cord-264532-xfb94lq8	16	26	Ewald	Ewald	NNP
cord-264532-xfb94lq8	16	27	1994	1994	CD
cord-264532-xfb94lq8	16	28	;	;	:
cord-264532-xfb94lq8	16	29	Gandon	Gandon	NNP
cord-264532-xfb94lq8	16	30	et	et	NNP
cord-264532-xfb94lq8	16	31	al	al	NNP
cord-264532-xfb94lq8	16	32	.	.	.
cord-264532-xfb94lq8	17	1	2001	2001	CD
cord-264532-xfb94lq8	18	1	Gandon	Gandon	NNP
cord-264532-xfb94lq8	18	2	et	et	NNP
cord-264532-xfb94lq8	18	3	al	al	NNP
cord-264532-xfb94lq8	18	4	.	.	NNP
cord-264532-xfb94lq8	18	5	,	,	,
cord-264532-xfb94lq8	18	6	2003	2003	CD
cord-264532-xfb94lq8	18	7	.	.	.
cord-264532-xfb94lq8	19	1	Typically	typically	RB
cord-264532-xfb94lq8	19	2	,	,	,
cord-264532-xfb94lq8	19	3	the	the	DT
cord-264532-xfb94lq8	19	4	models	model	NNS
cord-264532-xfb94lq8	19	5	of	of	IN
cord-264532-xfb94lq8	19	6	virulence	virulence	NN
cord-264532-xfb94lq8	19	7	management	management	NN
cord-264532-xfb94lq8	19	8	are	be	VBP
cord-264532-xfb94lq8	19	9	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	19	10	.	.	.
cord-264532-xfb94lq8	20	1	They	-PRON-	PRP
cord-264532-xfb94lq8	20	2	consider	consider	VBP
cord-264532-xfb94lq8	20	3	how	how	WRB
cord-264532-xfb94lq8	20	4	natural	natural	JJ
cord-264532-xfb94lq8	20	5	selection	selection	NN
cord-264532-xfb94lq8	20	6	of	of	IN
cord-264532-xfb94lq8	20	7	parasites	parasite	NNS
cord-264532-xfb94lq8	20	8	is	be	VBZ
cord-264532-xfb94lq8	20	9	expected	expect	VBN
cord-264532-xfb94lq8	20	10	to	to	TO
cord-264532-xfb94lq8	20	11	shape	shape	VB
cord-264532-xfb94lq8	20	12	the	the	DT
cord-264532-xfb94lq8	20	13	evolution	evolution	NN
cord-264532-xfb94lq8	20	14	of	of	IN
cord-264532-xfb94lq8	20	15	virulence	virulence	NN
cord-264532-xfb94lq8	20	16	and	and	CC
cord-264532-xfb94lq8	20	17	other	other	JJ
cord-264532-xfb94lq8	20	18	traits	trait	NNS
cord-264532-xfb94lq8	20	19	toward	toward	IN
cord-264532-xfb94lq8	20	20	states	state	NNS
cord-264532-xfb94lq8	20	21	that	that	WDT
cord-264532-xfb94lq8	20	22	maximize	maximize	VBP
cord-264532-xfb94lq8	20	23	fitness	fitness	NN
cord-264532-xfb94lq8	20	24	and	and	CC
cord-264532-xfb94lq8	20	25	the	the	DT
cord-264532-xfb94lq8	20	26	parasite	parasite	NN
cord-264532-xfb94lq8	20	27	optima	optima	NNP
cord-264532-xfb94lq8	20	28	.	.	.
cord-264532-xfb94lq8	21	1	The	the	DT
cord-264532-xfb94lq8	21	2	argument	argument	NN
cord-264532-xfb94lq8	21	3	put	put	VBD
cord-264532-xfb94lq8	21	4	forth	forth	RB
cord-264532-xfb94lq8	21	5	here	here	RB
cord-264532-xfb94lq8	21	6	is	be	VBZ
cord-264532-xfb94lq8	21	7	that	that	IN
cord-264532-xfb94lq8	21	8	this	this	DT
cord-264532-xfb94lq8	21	9	'	'	``
cord-264532-xfb94lq8	21	10	optimality	optimality	NN
cord-264532-xfb94lq8	21	11	'	'	''
cord-264532-xfb94lq8	21	12	approach	approach	NN
cord-264532-xfb94lq8	21	13	is	be	VBZ
cord-264532-xfb94lq8	21	14	not	not	RB
cord-264532-xfb94lq8	21	15	always	always	RB
cord-264532-xfb94lq8	21	16	suitable	suitable	JJ
cord-264532-xfb94lq8	21	17	,	,	,
cord-264532-xfb94lq8	21	18	because	because	IN
cord-264532-xfb94lq8	21	19	it	-PRON-	PRP
cord-264532-xfb94lq8	21	20	assumes	assume	VBZ
cord-264532-xfb94lq8	21	21	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	21	22	conditions	condition	NNS
cord-264532-xfb94lq8	21	23	that	that	WDT
cord-264532-xfb94lq8	21	24	some	some	DT
cord-264532-xfb94lq8	21	25	types	type	NNS
cord-264532-xfb94lq8	21	26	of	of	IN
cord-264532-xfb94lq8	21	27	parasites	parasite	NNS
cord-264532-xfb94lq8	21	28	may	may	MD
cord-264532-xfb94lq8	21	29	be	be	VB
cord-264532-xfb94lq8	21	30	slow	slow	JJ
cord-264532-xfb94lq8	21	31	to	to	TO
cord-264532-xfb94lq8	21	32	attain	attain	VB
cord-264532-xfb94lq8	21	33	.	.	.
cord-264532-xfb94lq8	22	1	Even	even	RB
cord-264532-xfb94lq8	22	2	for	for	IN
cord-264532-xfb94lq8	22	3	parasites	parasite	NNS
cord-264532-xfb94lq8	22	4	that	that	WDT
cord-264532-xfb94lq8	22	5	are	be	VBP
cord-264532-xfb94lq8	22	6	able	able	JJ
cord-264532-xfb94lq8	22	7	to	to	TO
cord-264532-xfb94lq8	22	8	evolve	evolve	VB
cord-264532-xfb94lq8	22	9	an	an	DT
cord-264532-xfb94lq8	22	10	optimum	optimum	JJ
cord-264532-xfb94lq8	22	11	virulence	virulence	NN
cord-264532-xfb94lq8	22	12	,	,	,
cord-264532-xfb94lq8	22	13	once	once	RB
cord-264532-xfb94lq8	22	14	a	a	DT
cord-264532-xfb94lq8	22	15	host	host	NN
cord-264532-xfb94lq8	22	16	population	population	NN
cord-264532-xfb94lq8	22	17	has	have	VBZ
cord-264532-xfb94lq8	22	18	a	a	DT
cord-264532-xfb94lq8	22	19	high	high	JJ
cord-264532-xfb94lq8	22	20	density	density	NN
cord-264532-xfb94lq8	22	21	of	of	IN
cord-264532-xfb94lq8	22	22	immune	immune	NN
cord-264532-xfb94lq8	22	23	or	or	CC
cord-264532-xfb94lq8	22	24	recovered	recover	VBN
cord-264532-xfb94lq8	22	25	individuals	individual	NNS
cord-264532-xfb94lq8	22	26	,	,	,
cord-264532-xfb94lq8	22	27	then	then	RB
cord-264532-xfb94lq8	22	28	that	that	DT
cord-264532-xfb94lq8	22	29	host	host	NN
cord-264532-xfb94lq8	22	30	population	population	NN
cord-264532-xfb94lq8	22	31	remains	remain	VBZ
cord-264532-xfb94lq8	22	32	vulnerable	vulnerable	JJ
cord-264532-xfb94lq8	22	33	to	to	IN
cord-264532-xfb94lq8	22	34	invasion	invasion	NN
cord-264532-xfb94lq8	22	35	by	by	IN
cord-264532-xfb94lq8	22	36	parasite	parasite	NN
cord-264532-xfb94lq8	22	37	genotypes	genotype	NNS
cord-264532-xfb94lq8	22	38	that	that	WDT
cord-264532-xfb94lq8	22	39	escape	escape	VBP
cord-264532-xfb94lq8	22	40	immunity	immunity	NN
cord-264532-xfb94lq8	22	41	.	.	.
cord-264532-xfb94lq8	23	1	During	during	IN
cord-264532-xfb94lq8	23	2	invasion	invasion	NN
cord-264532-xfb94lq8	23	3	,	,	,
cord-264532-xfb94lq8	23	4	a	a	DT
cord-264532-xfb94lq8	23	5	much	much	RB
cord-264532-xfb94lq8	23	6	wider	wide	JJR
cord-264532-xfb94lq8	23	7	range	range	NN
cord-264532-xfb94lq8	23	8	of	of	IN
cord-264532-xfb94lq8	23	9	virulence	virulence	NN
cord-264532-xfb94lq8	23	10	can	can	MD
cord-264532-xfb94lq8	23	11	spread	spread	VB
cord-264532-xfb94lq8	23	12	,	,	,
cord-264532-xfb94lq8	23	13	at	at	IN
cord-264532-xfb94lq8	23	14	least	least	JJS
cord-264532-xfb94lq8	23	15	temporarily	temporarily	RB
cord-264532-xfb94lq8	23	16	,	,	,
cord-264532-xfb94lq8	23	17	than	than	IN
cord-264532-xfb94lq8	23	18	is	be	VBZ
cord-264532-xfb94lq8	23	19	evident	evident	JJ
cord-264532-xfb94lq8	23	20	from	from	IN
cord-264532-xfb94lq8	23	21	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	23	22	optima	optima	NNP
cord-264532-xfb94lq8	23	23	.	.	.
cord-264532-xfb94lq8	24	1	The	the	DT
cord-264532-xfb94lq8	24	2	frequency	frequency	NN
cord-264532-xfb94lq8	24	3	of	of	IN
cord-264532-xfb94lq8	24	4	new	new	JJ
cord-264532-xfb94lq8	24	5	invasions	invasion	NNS
cord-264532-xfb94lq8	24	6	and	and	CC
cord-264532-xfb94lq8	24	7	the	the	DT
cord-264532-xfb94lq8	24	8	rapidity	rapidity	NN
cord-264532-xfb94lq8	24	9	with	with	IN
cord-264532-xfb94lq8	24	10	which	which	WDT
cord-264532-xfb94lq8	24	11	parasites	parasite	NNS
cord-264532-xfb94lq8	24	12	evolve	evolve	VBP
cord-264532-xfb94lq8	24	13	to	to	IN
cord-264532-xfb94lq8	24	14	their	-PRON-	PRP$
cord-264532-xfb94lq8	24	15	optima	optima	NNP
cord-264532-xfb94lq8	24	16	will	will	MD
cord-264532-xfb94lq8	24	17	dictate	dictate	VB
cord-264532-xfb94lq8	24	18	how	how	WRB
cord-264532-xfb94lq8	24	19	often	often	RB
cord-264532-xfb94lq8	24	20	the	the	DT
cord-264532-xfb94lq8	24	21	host	host	NN
cord-264532-xfb94lq8	24	22	experiences	experience	VBZ
cord-264532-xfb94lq8	24	23	nonoptimal	nonoptimal	JJ
cord-264532-xfb94lq8	24	24	parasite	parasite	NN
cord-264532-xfb94lq8	24	25	virulence	virulence	NN
cord-264532-xfb94lq8	24	26	.	.	.
cord-264532-xfb94lq8	25	1	We	-PRON-	PRP
cord-264532-xfb94lq8	25	2	develop	develop	VBP
cord-264532-xfb94lq8	25	3	this	this	DT
cord-264532-xfb94lq8	25	4	argument	argument	NN
cord-264532-xfb94lq8	25	5	in	in	IN
cord-264532-xfb94lq8	25	6	the	the	DT
cord-264532-xfb94lq8	25	7	context	context	NN
cord-264532-xfb94lq8	25	8	and	and	CC
cord-264532-xfb94lq8	25	9	framework	framework	NN
cord-264532-xfb94lq8	25	10	of	of	IN
cord-264532-xfb94lq8	25	11	the	the	DT
cord-264532-xfb94lq8	25	12	standard	standard	JJ
cord-264532-xfb94lq8	25	13	models	model	NNS
cord-264532-xfb94lq8	25	14	for	for	IN
cord-264532-xfb94lq8	25	15	the	the	DT
cord-264532-xfb94lq8	25	16	evolution	evolution	NN
cord-264532-xfb94lq8	25	17	of	of	IN
cord-264532-xfb94lq8	25	18	virulence	virulence	NN
cord-264532-xfb94lq8	25	19	,	,	,
cord-264532-xfb94lq8	25	20	models	model	NNS
cord-264532-xfb94lq8	25	21	that	that	WDT
cord-264532-xfb94lq8	25	22	address	address	VBP
cord-264532-xfb94lq8	25	23	virulence	virulence	NN
cord-264532-xfb94lq8	25	24	optima	optima	NNP
cord-264532-xfb94lq8	25	25	.	.	.
cord-264532-xfb94lq8	26	1	Two	two	CD
cord-264532-xfb94lq8	26	2	standard	standard	JJ
cord-264532-xfb94lq8	26	3	models	model	NNS
cord-264532-xfb94lq8	26	4	are	be	VBP
cord-264532-xfb94lq8	26	5	reviewed	review	VBN
cord-264532-xfb94lq8	26	6	.	.	.
cord-264532-xfb94lq8	27	1	They	-PRON-	PRP
cord-264532-xfb94lq8	27	2	differ	differ	VBP
cord-264532-xfb94lq8	27	3	in	in	IN
cord-264532-xfb94lq8	27	4	the	the	DT
cord-264532-xfb94lq8	27	5	state	state	NN
cord-264532-xfb94lq8	27	6	of	of	IN
cord-264532-xfb94lq8	27	7	host	host	NN
cord-264532-xfb94lq8	27	8	-	-	HYPH
cord-264532-xfb94lq8	27	9	parasite	parasite	NN
cord-264532-xfb94lq8	27	10	dynamics	dynamic	NNS
cord-264532-xfb94lq8	27	11	when	when	WRB
cord-264532-xfb94lq8	27	12	the	the	DT
cord-264532-xfb94lq8	27	13	virulence	virulence	NN
cord-264532-xfb94lq8	27	14	optimum	optimum	NN
cord-264532-xfb94lq8	27	15	is	be	VBZ
cord-264532-xfb94lq8	27	16	calculated	calculate	VBN
cord-264532-xfb94lq8	27	17	,	,	,
cord-264532-xfb94lq8	27	18	but	but	CC
cord-264532-xfb94lq8	27	19	they	-PRON-	PRP
cord-264532-xfb94lq8	27	20	both	both	DT
cord-264532-xfb94lq8	27	21	illustrate	illustrate	VBP
cord-264532-xfb94lq8	27	22	the	the	DT
cord-264532-xfb94lq8	27	23	same	same	JJ
cord-264532-xfb94lq8	27	24	general	general	JJ
cord-264532-xfb94lq8	27	25	approach	approach	NN
cord-264532-xfb94lq8	27	26	.	.	.
cord-264532-xfb94lq8	28	1	Those	those	DT
cord-264532-xfb94lq8	28	2	models	model	NNS
cord-264532-xfb94lq8	28	3	are	be	VBP
cord-264532-xfb94lq8	28	4	then	then	RB
cord-264532-xfb94lq8	28	5	extended	extend	VBN
cord-264532-xfb94lq8	28	6	to	to	IN
cord-264532-xfb94lq8	28	7	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	28	8	conditions	condition	NNS
cord-264532-xfb94lq8	28	9	.	.	.
cord-264532-xfb94lq8	29	1	Our	-PRON-	PRP$
cord-264532-xfb94lq8	29	2	use	use	NN
cord-264532-xfb94lq8	29	3	of	of	IN
cord-264532-xfb94lq8	29	4	those	those	DT
cord-264532-xfb94lq8	29	5	simplistic	simplistic	JJ
cord-264532-xfb94lq8	29	6	models	model	NNS
cord-264532-xfb94lq8	29	7	is	be	VBZ
cord-264532-xfb94lq8	29	8	for	for	IN
cord-264532-xfb94lq8	29	9	ease	ease	NN
cord-264532-xfb94lq8	29	10	of	of	IN
cord-264532-xfb94lq8	29	11	illustration	illustration	NN
cord-264532-xfb94lq8	29	12	in	in	IN
cord-264532-xfb94lq8	29	13	a	a	DT
cord-264532-xfb94lq8	29	14	familiar	familiar	JJ
cord-264532-xfb94lq8	29	15	context	context	NN
cord-264532-xfb94lq8	29	16	.	.	.
cord-264532-xfb94lq8	30	1	Our	-PRON-	PRP$
cord-264532-xfb94lq8	30	2	neglect	neglect	NN
cord-264532-xfb94lq8	30	3	of	of	IN
cord-264532-xfb94lq8	30	4	more	more	RBR
cord-264532-xfb94lq8	30	5	complicated	complicated	JJ
cord-264532-xfb94lq8	30	6	processes	process	NNS
cord-264532-xfb94lq8	30	7	,	,	,
cord-264532-xfb94lq8	30	8	such	such	JJ
cord-264532-xfb94lq8	30	9	as	as	IN
cord-264532-xfb94lq8	30	10	within	within	IN
cord-264532-xfb94lq8	30	11	-	-	HYPH
cord-264532-xfb94lq8	30	12	host	host	NN
cord-264532-xfb94lq8	30	13	dynamics	dynamic	NNS
cord-264532-xfb94lq8	30	14	(	(	-LRB-
cord-264532-xfb94lq8	30	15	Ball	Ball	NNP
cord-264532-xfb94lq8	30	16	et	et	FW
cord-264532-xfb94lq8	30	17	al	al	NNP
cord-264532-xfb94lq8	30	18	.	.	NNP
cord-264532-xfb94lq8	30	19	2007	2007	CD
cord-264532-xfb94lq8	30	20	)	)	-RRB-
cord-264532-xfb94lq8	30	21	,	,	,
cord-264532-xfb94lq8	30	22	within	within	IN
cord-264532-xfb94lq8	30	23	-	-	HYPH
cord-264532-xfb94lq8	30	24	host	host	NN
cord-264532-xfb94lq8	30	25	combined	combine	VBN
cord-264532-xfb94lq8	30	26	with	with	IN
cord-264532-xfb94lq8	30	27	betweenhost	betweenhost	NN
cord-264532-xfb94lq8	30	28	dynamics	dynamic	NNS
cord-264532-xfb94lq8	30	29	(	(	-LRB-
cord-264532-xfb94lq8	30	30	Gilchrist	Gilchrist	NNP
cord-264532-xfb94lq8	30	31	and	and	CC
cord-264532-xfb94lq8	30	32	Coombs	Coombs	NNP
cord-264532-xfb94lq8	30	33	2006	2006	CD
cord-264532-xfb94lq8	30	34	)	)	-RRB-
cord-264532-xfb94lq8	30	35	,	,	,
cord-264532-xfb94lq8	30	36	or	or	CC
cord-264532-xfb94lq8	30	37	of	of	IN
cord-264532-xfb94lq8	30	38	virulence	virulence	NN
cord-264532-xfb94lq8	30	39	models	model	NNS
cord-264532-xfb94lq8	30	40	that	that	WDT
cord-264532-xfb94lq8	30	41	lack	lack	VBP
cord-264532-xfb94lq8	30	42	optima	optima	NNP
cord-264532-xfb94lq8	30	43	(	(	-LRB-
cord-264532-xfb94lq8	30	44	Dieckmann	Dieckmann	NNP
cord-264532-xfb94lq8	30	45	2002	2002	CD
cord-264532-xfb94lq8	30	46	)	)	-RRB-
cord-264532-xfb94lq8	30	47	is	be	VBZ
cord-264532-xfb94lq8	30	48	not	not	RB
cord-264532-xfb94lq8	30	49	to	to	TO
cord-264532-xfb94lq8	30	50	deny	deny	VB
cord-264532-xfb94lq8	30	51	the	the	DT
cord-264532-xfb94lq8	30	52	importance	importance	NN
cord-264532-xfb94lq8	30	53	of	of	IN
cord-264532-xfb94lq8	30	54	those	those	DT
cord-264532-xfb94lq8	30	55	alternatives	alternative	NNS
cord-264532-xfb94lq8	30	56	.	.	.
cord-264532-xfb94lq8	31	1	Indeed	indeed	RB
cord-264532-xfb94lq8	31	2	,	,	,
cord-264532-xfb94lq8	31	3	the	the	DT
cord-264532-xfb94lq8	31	4	concept	concept	NN
cord-264532-xfb94lq8	31	5	of	of	IN
cord-264532-xfb94lq8	31	6	a	a	DT
cord-264532-xfb94lq8	31	7	delayed	delay	VBN
cord-264532-xfb94lq8	31	8	approach	approach	NN
cord-264532-xfb94lq8	31	9	to	to	IN
cord-264532-xfb94lq8	31	10	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	31	11	conditions	condition	NNS
cord-264532-xfb94lq8	31	12	can	can	MD
cord-264532-xfb94lq8	31	13	be	be	VB
cord-264532-xfb94lq8	31	14	applied	apply	VBN
cord-264532-xfb94lq8	31	15	to	to	IN
cord-264532-xfb94lq8	31	16	many	many	JJ
cord-264532-xfb94lq8	31	17	of	of	IN
cord-264532-xfb94lq8	31	18	those	those	DT
cord-264532-xfb94lq8	31	19	and	and	CC
cord-264532-xfb94lq8	31	20	other	other	JJ
cord-264532-xfb94lq8	31	21	types	type	NNS
cord-264532-xfb94lq8	31	22	of	of	IN
cord-264532-xfb94lq8	31	23	models	model	NNS
cord-264532-xfb94lq8	31	24	.	.	.
cord-264532-xfb94lq8	32	1	Furthermore	furthermore	RB
cord-264532-xfb94lq8	32	2	,	,	,
cord-264532-xfb94lq8	32	3	the	the	DT
cord-264532-xfb94lq8	32	4	process	process	NN
cord-264532-xfb94lq8	32	5	we	-PRON-	PRP
cord-264532-xfb94lq8	32	6	describe	describe	VBP
cord-264532-xfb94lq8	32	7	is	be	VBZ
cord-264532-xfb94lq8	32	8	fully	fully	RB
cord-264532-xfb94lq8	32	9	and	and	CC
cord-264532-xfb94lq8	32	10	properly	properly	RB
cord-264532-xfb94lq8	32	11	encompassed	encompass	VBN
cord-264532-xfb94lq8	32	12	in	in	IN
cord-264532-xfb94lq8	32	13	the	the	DT
cord-264532-xfb94lq8	32	14	new	new	JJ
cord-264532-xfb94lq8	32	15	formalism	formalism	NN
cord-264532-xfb94lq8	32	16	of	of	IN
cord-264532-xfb94lq8	32	17	Gandon	Gandon	NNP
cord-264532-xfb94lq8	32	18	(	(	-LRB-
cord-264532-xfb94lq8	32	19	2006	2006	CD
cord-264532-xfb94lq8	32	20	,	,	,
cord-264532-xfb94lq8	32	21	2007	2007	CD
cord-264532-xfb94lq8	32	22	)	)	-RRB-
cord-264532-xfb94lq8	32	23	and	and	CC
cord-264532-xfb94lq8	32	24	Day	Day	NNP
cord-264532-xfb94lq8	32	25	and	and	CC
cord-264532-xfb94lq8	32	26	Proulx	Proulx	NNP
cord-264532-xfb94lq8	32	27	(	(	-LRB-
cord-264532-xfb94lq8	32	28	2004	2004	CD
cord-264532-xfb94lq8	32	29	)	)	-RRB-
cord-264532-xfb94lq8	32	30	,	,	,
cord-264532-xfb94lq8	32	31	albeit	albeit	IN
cord-264532-xfb94lq8	32	32	that	that	IN
cord-264532-xfb94lq8	32	33	their	-PRON-	PRP$
cord-264532-xfb94lq8	32	34	formalism	formalism	NN
cord-264532-xfb94lq8	32	35	encompasses	encompass	VBZ
cord-264532-xfb94lq8	32	36	a	a	DT
cord-264532-xfb94lq8	32	37	far	far	RB
cord-264532-xfb94lq8	32	38	wider	wide	JJR
cord-264532-xfb94lq8	32	39	range	range	NN
cord-264532-xfb94lq8	32	40	of	of	IN
cord-264532-xfb94lq8	32	41	possibilities	possibility	NNS
cord-264532-xfb94lq8	32	42	than	than	IN
cord-264532-xfb94lq8	32	43	the	the	DT
cord-264532-xfb94lq8	32	44	ones	one	NNS
cord-264532-xfb94lq8	32	45	we	-PRON-	PRP
cord-264532-xfb94lq8	32	46	emphasize	emphasize	VBP
cord-264532-xfb94lq8	32	47	.	.	.
cord-264532-xfb94lq8	33	1	Optimal	optimal	JJ
cord-264532-xfb94lq8	33	2	virulence	virulence	NN
cord-264532-xfb94lq8	33	3	theories	theory	NNS
cord-264532-xfb94lq8	33	4	R	r	NN
cord-264532-xfb94lq8	33	5	0	0	CD
cord-264532-xfb94lq8	33	6	perspective	perspective	NN
cord-264532-xfb94lq8	34	1	The	the	DT
cord-264532-xfb94lq8	34	2	now	now	RB
cord-264532-xfb94lq8	34	3	conventional	conventional	JJ
cord-264532-xfb94lq8	34	4	method	method	NN
cord-264532-xfb94lq8	34	5	for	for	IN
cord-264532-xfb94lq8	34	6	considering	consider	VBG
cord-264532-xfb94lq8	34	7	the	the	DT
cord-264532-xfb94lq8	34	8	evolution	evolution	NN
cord-264532-xfb94lq8	34	9	of	of	IN
cord-264532-xfb94lq8	34	10	virulence	virulence	NN
cord-264532-xfb94lq8	34	11	is	be	VBZ
cord-264532-xfb94lq8	34	12	about	about	RB
cord-264532-xfb94lq8	34	13	three	three	CD
cord-264532-xfb94lq8	34	14	decades	decade	NNS
cord-264532-xfb94lq8	34	15	old	old	JJ
cord-264532-xfb94lq8	34	16	May	May	NNP
cord-264532-xfb94lq8	34	17	1979	1979	CD
cord-264532-xfb94lq8	34	18	,	,	,
cord-264532-xfb94lq8	34	19	1982	1982	CD
cord-264532-xfb94lq8	34	20	)	)	-RRB-
cord-264532-xfb94lq8	34	21	.	.	.
cord-264532-xfb94lq8	35	1	It	-PRON-	PRP
cord-264532-xfb94lq8	35	2	assumes	assume	VBZ
cord-264532-xfb94lq8	35	3	that	that	IN
cord-264532-xfb94lq8	35	4	the	the	DT
cord-264532-xfb94lq8	35	5	parasite	parasite	NN
cord-264532-xfb94lq8	35	6	population	population	NN
cord-264532-xfb94lq8	35	7	has	have	VBZ
cord-264532-xfb94lq8	35	8	gone	go	VBN
cord-264532-xfb94lq8	35	9	to	to	IN
cord-264532-xfb94lq8	35	10	its	-PRON-	PRP$
cord-264532-xfb94lq8	35	11	dynamic	dynamic	JJ
cord-264532-xfb94lq8	35	12	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	35	13	(	(	-LRB-
cord-264532-xfb94lq8	35	14	the	the	DT
cord-264532-xfb94lq8	35	15	endemic	endemic	JJ
cord-264532-xfb94lq8	35	16	phase	phase	NN
cord-264532-xfb94lq8	35	17	)	)	-RRB-
cord-264532-xfb94lq8	35	18	,	,	,
cord-264532-xfb94lq8	35	19	such	such	JJ
cord-264532-xfb94lq8	35	20	that	that	IN
cord-264532-xfb94lq8	35	21	the	the	DT
cord-264532-xfb94lq8	35	22	parasite	parasite	NN
cord-264532-xfb94lq8	35	23	population	population	NN
cord-264532-xfb94lq8	35	24	is	be	VBZ
cord-264532-xfb94lq8	35	25	no	no	RB
cord-264532-xfb94lq8	35	26	longer	long	RBR
cord-264532-xfb94lq8	35	27	spreading	spread	VBG
cord-264532-xfb94lq8	35	28	in	in	IN
cord-264532-xfb94lq8	35	29	the	the	DT
cord-264532-xfb94lq8	35	30	host	host	NN
cord-264532-xfb94lq8	35	31	population	population	NN
cord-264532-xfb94lq8	35	32	.	.	.
cord-264532-xfb94lq8	36	1	This	this	DT
cord-264532-xfb94lq8	36	2	model	model	NN
cord-264532-xfb94lq8	36	3	identifies	identify	VBZ
cord-264532-xfb94lq8	36	4	the	the	DT
cord-264532-xfb94lq8	36	5	combination	combination	NN
cord-264532-xfb94lq8	36	6	of	of	IN
cord-264532-xfb94lq8	36	7	transmission	transmission	NN
cord-264532-xfb94lq8	36	8	and	and	CC
cord-264532-xfb94lq8	36	9	virulence	virulence	NN
cord-264532-xfb94lq8	36	10	that	that	WDT
cord-264532-xfb94lq8	36	11	leads	lead	VBZ
cord-264532-xfb94lq8	36	12	to	to	IN
cord-264532-xfb94lq8	36	13	highest	high	JJS
cord-264532-xfb94lq8	36	14	parasite	parasite	NN
cord-264532-xfb94lq8	36	15	fitness	fitness	NN
cord-264532-xfb94lq8	36	16	.	.	.
cord-264532-xfb94lq8	37	1	The	the	DT
cord-264532-xfb94lq8	37	2	result	result	NN
cord-264532-xfb94lq8	37	3	is	be	VBZ
cord-264532-xfb94lq8	37	4	that	that	IN
cord-264532-xfb94lq8	37	5	selection	selection	NN
cord-264532-xfb94lq8	37	6	maximizes	maximize	VBZ
cord-264532-xfb94lq8	37	7	the	the	DT
cord-264532-xfb94lq8	37	8	parasite	parasite	NN
cord-264532-xfb94lq8	37	9	reproductive	reproductive	JJ
cord-264532-xfb94lq8	37	10	number	number	NN
cord-264532-xfb94lq8	37	11	,	,	,
cord-264532-xfb94lq8	37	12	R	r	NN
cord-264532-xfb94lq8	37	13	0	0	CD
cord-264532-xfb94lq8	37	14	(	(	-LRB-
cord-264532-xfb94lq8	37	15	or	or	CC
cord-264532-xfb94lq8	37	16	more	more	RBR
cord-264532-xfb94lq8	37	17	properly	properly	RB
cord-264532-xfb94lq8	37	18	,	,	,
cord-264532-xfb94lq8	37	19	maximizes	maximize	VBZ
cord-264532-xfb94lq8	37	20	R	r	NN
cord-264532-xfb94lq8	37	21	;	;	:
cord-264532-xfb94lq8	37	22	Day	Day	NNP
cord-264532-xfb94lq8	37	23	and	and	CC
cord-264532-xfb94lq8	37	24	Gandon	Gandon	NNP
cord-264532-xfb94lq8	37	25	2007	2007	CD
cord-264532-xfb94lq8	37	26	)	)	-RRB-
cord-264532-xfb94lq8	37	27	.	.	.
cord-264532-xfb94lq8	38	1	R	r	NN
cord-264532-xfb94lq8	38	2	0	0	CD
cord-264532-xfb94lq8	38	3	is	be	VBZ
cord-264532-xfb94lq8	38	4	a	a	DT
cord-264532-xfb94lq8	38	5	dimensionless	dimensionless	JJ
cord-264532-xfb94lq8	38	6	number	number	NN
cord-264532-xfb94lq8	38	7	that	that	WDT
cord-264532-xfb94lq8	38	8	equals	equal	VBZ
cord-264532-xfb94lq8	38	9	the	the	DT
cord-264532-xfb94lq8	38	10	number	number	NN
cord-264532-xfb94lq8	38	11	of	of	IN
cord-264532-xfb94lq8	38	12	new	new	JJ
cord-264532-xfb94lq8	38	13	infections	infection	NNS
cord-264532-xfb94lq8	38	14	started	start	VBD
cord-264532-xfb94lq8	38	15	during	during	IN
cord-264532-xfb94lq8	38	16	the	the	DT
cord-264532-xfb94lq8	38	17	lifetime	lifetime	NN
cord-264532-xfb94lq8	38	18	of	of	IN
cord-264532-xfb94lq8	38	19	the	the	DT
cord-264532-xfb94lq8	38	20	first	first	JJ
cord-264532-xfb94lq8	38	21	infected	infected	JJ
cord-264532-xfb94lq8	38	22	individual	individual	NN
cord-264532-xfb94lq8	38	23	in	in	IN
cord-264532-xfb94lq8	38	24	a	a	DT
cord-264532-xfb94lq8	38	25	susceptible	susceptible	JJ
cord-264532-xfb94lq8	38	26	population	population	NN
cord-264532-xfb94lq8	39	1	(	(	-LRB-
cord-264532-xfb94lq8	39	2	R	r	NN
cord-264532-xfb94lq8	39	3	is	be	VBZ
cord-264532-xfb94lq8	39	4	the	the	DT
cord-264532-xfb94lq8	39	5	number	number	NN
cord-264532-xfb94lq8	39	6	of	of	IN
cord-264532-xfb94lq8	39	7	new	new	JJ
cord-264532-xfb94lq8	39	8	infections	infection	NNS
cord-264532-xfb94lq8	39	9	from	from	IN
cord-264532-xfb94lq8	39	10	an	an	DT
cord-264532-xfb94lq8	39	11	infected	infected	JJ
cord-264532-xfb94lq8	39	12	individual	individual	NN
cord-264532-xfb94lq8	39	13	once	once	IN
cord-264532-xfb94lq8	39	14	the	the	DT
cord-264532-xfb94lq8	39	15	parasite	parasite	NN
cord-264532-xfb94lq8	39	16	has	have	VBZ
cord-264532-xfb94lq8	39	17	established	establish	VBN
cord-264532-xfb94lq8	39	18	itself	-PRON-	PRP
cord-264532-xfb94lq8	39	19	in	in	IN
cord-264532-xfb94lq8	39	20	the	the	DT
cord-264532-xfb94lq8	39	21	host	host	NN
cord-264532-xfb94lq8	39	22	population	population	NN
cord-264532-xfb94lq8	39	23	.	.	.
cord-264532-xfb94lq8	39	24	)	)	-RRB-
cord-264532-xfb94lq8	40	1	The	the	DT
cord-264532-xfb94lq8	40	2	formula	formula	NN
cord-264532-xfb94lq8	40	3	for	for	IN
cord-264532-xfb94lq8	40	4	R	r	NN
cord-264532-xfb94lq8	40	5	0	0	CD
cord-264532-xfb94lq8	40	6	is	be	VBZ
cord-264532-xfb94lq8	40	7	simply	simply	RB
cord-264532-xfb94lq8	40	8	the	the	DT
cord-264532-xfb94lq8	40	9	parasite	parasite	NN
cord-264532-xfb94lq8	40	10	fecundity	fecundity	NN
cord-264532-xfb94lq8	40	11	rate	rate	NN
cord-264532-xfb94lq8	40	12	times	time	NNS
cord-264532-xfb94lq8	40	13	the	the	DT
cord-264532-xfb94lq8	40	14	average	average	JJ
cord-264532-xfb94lq8	40	15	lifetime	lifetime	NN
cord-264532-xfb94lq8	40	16	of	of	IN
cord-264532-xfb94lq8	40	17	the	the	DT
cord-264532-xfb94lq8	40	18	infection	infection	NN
cord-264532-xfb94lq8	40	19	.	.	.
cord-264532-xfb94lq8	41	1	Although	although	IN
cord-264532-xfb94lq8	41	2	R	r	NN
cord-264532-xfb94lq8	41	3	0	0	CD
cord-264532-xfb94lq8	41	4	is	be	VBZ
cord-264532-xfb94lq8	41	5	defined	define	VBN
cord-264532-xfb94lq8	41	6	for	for	IN
cord-264532-xfb94lq8	41	7	the	the	DT
cord-264532-xfb94lq8	41	8	first	first	JJ
cord-264532-xfb94lq8	41	9	infected	infected	JJ
cord-264532-xfb94lq8	41	10	host	host	NN
cord-264532-xfb94lq8	41	11	in	in	IN
cord-264532-xfb94lq8	41	12	a	a	DT
cord-264532-xfb94lq8	41	13	naive	naive	JJ
cord-264532-xfb94lq8	41	14	population	population	NN
cord-264532-xfb94lq8	41	15	,	,	,
cord-264532-xfb94lq8	41	16	what	what	WP
cord-264532-xfb94lq8	41	17	maximizes	maximize	VBZ
cord-264532-xfb94lq8	41	18	R	r	NN
cord-264532-xfb94lq8	41	19	0	0	CD
cord-264532-xfb94lq8	41	20	also	also	RB
cord-264532-xfb94lq8	41	21	maximizes	maximize	VBZ
cord-264532-xfb94lq8	41	22	R	r	NN
cord-264532-xfb94lq8	41	23	because	because	IN
cord-264532-xfb94lq8	41	24	the	the	DT
cord-264532-xfb94lq8	41	25	only	only	JJ
cord-264532-xfb94lq8	41	26	difference	difference	NN
cord-264532-xfb94lq8	41	27	between	between	IN
cord-264532-xfb94lq8	41	28	them	-PRON-	PRP
cord-264532-xfb94lq8	41	29	lies	lie	VBZ
cord-264532-xfb94lq8	41	30	in	in	IN
cord-264532-xfb94lq8	41	31	the	the	DT
cord-264532-xfb94lq8	41	32	value	value	NN
cord-264532-xfb94lq8	41	33	of	of	IN
cord-264532-xfb94lq8	41	34	S	S	NNP
cord-264532-xfb94lq8	41	35	(	(	-LRB-
cord-264532-xfb94lq8	41	36	Ebert	Ebert	NNP
cord-264532-xfb94lq8	41	37	and	and	CC
cord-264532-xfb94lq8	41	38	Herre	Herre	NNP
cord-264532-xfb94lq8	41	39	1996	1996	CD
cord-264532-xfb94lq8	41	40	;	;	:
cord-264532-xfb94lq8	42	1	Day	Day	NNP
cord-264532-xfb94lq8	42	2	and	and	CC
cord-264532-xfb94lq8	42	3	Gandon	Gandon	NNP
cord-264532-xfb94lq8	42	4	2006	2006	CD
cord-264532-xfb94lq8	42	5	;	;	:
cord-264532-xfb94lq8	42	6	Gilchrist	Gilchrist	NNP
cord-264532-xfb94lq8	42	7	and	and	CC
cord-264532-xfb94lq8	42	8	Coombs	Coombs	NNP
cord-264532-xfb94lq8	42	9	2006	2006	CD
cord-264532-xfb94lq8	42	10	)	)	-RRB-
cord-264532-xfb94lq8	42	11	.	.	.
cord-264532-xfb94lq8	43	1	The	the	DT
cord-264532-xfb94lq8	43	2	result	result	NN
cord-264532-xfb94lq8	43	3	that	that	IN
cord-264532-xfb94lq8	43	4	selection	selection	NN
cord-264532-xfb94lq8	43	5	at	at	IN
cord-264532-xfb94lq8	43	6	the	the	DT
cord-264532-xfb94lq8	43	7	dynamic	dynamic	JJ
cord-264532-xfb94lq8	43	8	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	43	9	favors	favor	VBZ
cord-264532-xfb94lq8	43	10	maximization	maximization	NN
cord-264532-xfb94lq8	43	11	of	of	IN
cord-264532-xfb94lq8	43	12	R	r	NN
cord-264532-xfb94lq8	43	13	0	0	CD
cord-264532-xfb94lq8	43	14	parallels	parallel	VBZ
cord-264532-xfb94lq8	43	15	the	the	DT
cord-264532-xfb94lq8	43	16	usual	usual	JJ
cord-264532-xfb94lq8	43	17	demographic	demographic	JJ
cord-264532-xfb94lq8	43	18	result	result	NN
cord-264532-xfb94lq8	43	19	that	that	IN
cord-264532-xfb94lq8	43	20	selection	selection	NN
cord-264532-xfb94lq8	43	21	favors	favor	VBZ
cord-264532-xfb94lq8	43	22	maximal	maximal	JJ
cord-264532-xfb94lq8	43	23	lifetime	lifetime	NN
cord-264532-xfb94lq8	43	24	reproductive	reproductive	JJ
cord-264532-xfb94lq8	43	25	output	output	NN
cord-264532-xfb94lq8	43	26	in	in	IN
cord-264532-xfb94lq8	43	27	a	a	DT
cord-264532-xfb94lq8	43	28	stable	stable	JJ
cord-264532-xfb94lq8	43	29	population	population	NN
cord-264532-xfb94lq8	43	30	(	(	-LRB-
cord-264532-xfb94lq8	43	31	Wilson	Wilson	NNP
cord-264532-xfb94lq8	43	32	and	and	CC
cord-264532-xfb94lq8	43	33	Bossert	Bossert	NNP
cord-264532-xfb94lq8	43	34	1971	1971	CD
cord-264532-xfb94lq8	43	35	;	;	:
cord-264532-xfb94lq8	43	36	Charlesworth	Charlesworth	NNP
cord-264532-xfb94lq8	43	37	1994	1994	CD
cord-264532-xfb94lq8	43	38	)	)	-RRB-
cord-264532-xfb94lq8	43	39	.	.	.
cord-264532-xfb94lq8	44	1	We	-PRON-	PRP
cord-264532-xfb94lq8	44	2	will	will	MD
cord-264532-xfb94lq8	44	3	expand	expand	VB
cord-264532-xfb94lq8	44	4	on	on	IN
cord-264532-xfb94lq8	44	5	the	the	DT
cord-264532-xfb94lq8	44	6	implications	implication	NNS
cord-264532-xfb94lq8	44	7	of	of	IN
cord-264532-xfb94lq8	44	8	R	r	NN
cord-264532-xfb94lq8	44	9	0	0	CD
cord-264532-xfb94lq8	44	10	maximization	maximization	NN
cord-264532-xfb94lq8	44	11	below	below	RB
cord-264532-xfb94lq8	44	12	,	,	,
cord-264532-xfb94lq8	44	13	but	but	CC
cord-264532-xfb94lq8	44	14	it	-PRON-	PRP
cord-264532-xfb94lq8	44	15	is	be	VBZ
cord-264532-xfb94lq8	44	16	most	most	RBS
cord-264532-xfb94lq8	44	17	informative	informative	JJ
cord-264532-xfb94lq8	44	18	to	to	TO
cord-264532-xfb94lq8	44	19	do	do	VB
cord-264532-xfb94lq8	44	20	so	so	RB
cord-264532-xfb94lq8	44	21	in	in	IN
cord-264532-xfb94lq8	44	22	the	the	DT
cord-264532-xfb94lq8	44	23	broader	broad	JJR
cord-264532-xfb94lq8	44	24	context	context	NN
cord-264532-xfb94lq8	44	25	of	of	IN
cord-264532-xfb94lq8	44	26	the	the	DT
cord-264532-xfb94lq8	44	27	second	second	JJ
cord-264532-xfb94lq8	44	28	virulence	virulence	NN
cord-264532-xfb94lq8	44	29	evolution	evolution	NN
cord-264532-xfb94lq8	44	30	model	model	NN
cord-264532-xfb94lq8	44	31	,	,	,
cord-264532-xfb94lq8	44	32	considered	consider	VBN
cord-264532-xfb94lq8	44	33	next	next	RB
cord-264532-xfb94lq8	44	34	.	.	.
cord-264532-xfb94lq8	45	1	Lenski	Lenski	NNP
cord-264532-xfb94lq8	45	2	and	and	CC
cord-264532-xfb94lq8	45	3	May	May	NNP
cord-264532-xfb94lq8	45	4	(	(	-LRB-
cord-264532-xfb94lq8	45	5	1994	1994	CD
cord-264532-xfb94lq8	45	6	)	)	-RRB-
cord-264532-xfb94lq8	45	7	pointed	point	VBD
cord-264532-xfb94lq8	45	8	out	out	RP
cord-264532-xfb94lq8	45	9	that	that	IN
cord-264532-xfb94lq8	45	10	selection	selection	NN
cord-264532-xfb94lq8	45	11	on	on	IN
cord-264532-xfb94lq8	45	12	parasite	parasite	NN
cord-264532-xfb94lq8	45	13	parameters	parameter	NNS
cord-264532-xfb94lq8	45	14	was	be	VBD
cord-264532-xfb94lq8	45	15	different	different	JJ
cord-264532-xfb94lq8	45	16	during	during	IN
cord-264532-xfb94lq8	45	17	the	the	DT
cord-264532-xfb94lq8	45	18	epidemic	epidemic	NN
cord-264532-xfb94lq8	45	19	phase	phase	NN
cord-264532-xfb94lq8	45	20	than	than	IN
cord-264532-xfb94lq8	45	21	at	at	IN
cord-264532-xfb94lq8	45	22	dynamic	dynamic	JJ
cord-264532-xfb94lq8	45	23	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	45	24	:	:	:
cord-264532-xfb94lq8	45	25	maximizing	maximize	VBG
cord-264532-xfb94lq8	45	26	R	r	NN
cord-264532-xfb94lq8	45	27	0	0	CD
cord-264532-xfb94lq8	45	28	no	no	RB
cord-264532-xfb94lq8	45	29	longer	long	RBR
cord-264532-xfb94lq8	45	30	maximized	maximize	VBN
cord-264532-xfb94lq8	45	31	fitness	fitness	NN
cord-264532-xfb94lq8	45	32	if	if	IN
cord-264532-xfb94lq8	45	33	the	the	DT
cord-264532-xfb94lq8	45	34	parasite	parasite	NN
cord-264532-xfb94lq8	45	35	population	population	NN
cord-264532-xfb94lq8	45	36	was	be	VBD
cord-264532-xfb94lq8	45	37	expanding	expand	VBG
cord-264532-xfb94lq8	45	38	.	.	.
cord-264532-xfb94lq8	46	1	Again	again	RB
cord-264532-xfb94lq8	46	2	from	from	IN
cord-264532-xfb94lq8	46	3	demography	demography	NN
cord-264532-xfb94lq8	46	4	,	,	,
cord-264532-xfb94lq8	46	5	selection	selection	NN
cord-264532-xfb94lq8	46	6	favors	favor	VBZ
cord-264532-xfb94lq8	46	7	early	early	JJ
cord-264532-xfb94lq8	46	8	births	birth	NNS
cord-264532-xfb94lq8	46	9	over	over	IN
cord-264532-xfb94lq8	46	10	late	late	JJ
cord-264532-xfb94lq8	46	11	ones	one	NNS
cord-264532-xfb94lq8	46	12	in	in	IN
cord-264532-xfb94lq8	46	13	a	a	DT
cord-264532-xfb94lq8	46	14	growing	grow	VBG
cord-264532-xfb94lq8	46	15	population	population	NN
cord-264532-xfb94lq8	46	16	,	,	,
cord-264532-xfb94lq8	46	17	so	so	RB
cord-264532-xfb94lq8	46	18	during	during	IN
cord-264532-xfb94lq8	46	19	the	the	DT
cord-264532-xfb94lq8	46	20	epidemic	epidemic	NN
cord-264532-xfb94lq8	46	21	phase	phase	NN
cord-264532-xfb94lq8	46	22	,	,	,
cord-264532-xfb94lq8	46	23	there	there	EX
cord-264532-xfb94lq8	46	24	is	be	VBZ
cord-264532-xfb94lq8	46	25	a	a	DT
cord-264532-xfb94lq8	46	26	benefit	benefit	NN
cord-264532-xfb94lq8	46	27	to	to	IN
cord-264532-xfb94lq8	46	28	early	early	JJ
cord-264532-xfb94lq8	46	29	transmission	transmission	NN
cord-264532-xfb94lq8	46	30	and	and	CC
cord-264532-xfb94lq8	46	31	its	-PRON-	PRP$
cord-264532-xfb94lq8	46	32	consequent	consequent	JJ
cord-264532-xfb94lq8	46	33	shorter	short	JJR
cord-264532-xfb94lq8	46	34	generation	generation	NN
cord-264532-xfb94lq8	46	35	time	time	NN
cord-264532-xfb94lq8	46	36	even	even	RB
cord-264532-xfb94lq8	46	37	when	when	WRB
cord-264532-xfb94lq8	46	38	it	-PRON-	PRP
cord-264532-xfb94lq8	46	39	lowers	lower	VBZ
cord-264532-xfb94lq8	46	40	life	life	NN
cord-264532-xfb94lq8	46	41	-	-	HYPH
cord-264532-xfb94lq8	46	42	time	time	NN
cord-264532-xfb94lq8	46	43	reproductive	reproductive	JJ
cord-264532-xfb94lq8	46	44	success	success	NN
cord-264532-xfb94lq8	46	45	of	of	IN
cord-264532-xfb94lq8	46	46	the	the	DT
cord-264532-xfb94lq8	46	47	infection	infection	NN
cord-264532-xfb94lq8	46	48	.	.	.
cord-264532-xfb94lq8	47	1	In	in	IN
cord-264532-xfb94lq8	47	2	the	the	DT
cord-264532-xfb94lq8	47	3	model	model	NN
cord-264532-xfb94lq8	47	4	,	,	,
cord-264532-xfb94lq8	47	5	earlier	early	JJR
cord-264532-xfb94lq8	47	6	reproduction	reproduction	NN
cord-264532-xfb94lq8	47	7	is	be	VBZ
cord-264532-xfb94lq8	47	8	achieved	achieve	VBN
cord-264532-xfb94lq8	47	9	by	by	IN
cord-264532-xfb94lq8	47	10	a	a	DT
cord-264532-xfb94lq8	47	11	higher	high	JJR
cord-264532-xfb94lq8	47	12	transmission	transmission	NN
cord-264532-xfb94lq8	47	13	rate	rate	NN
cord-264532-xfb94lq8	47	14	,	,	,
cord-264532-xfb94lq8	47	15	which	which	WDT
cord-264532-xfb94lq8	47	16	in	in	IN
cord-264532-xfb94lq8	47	17	most	most	JJS
cord-264532-xfb94lq8	47	18	models	model	NNS
cord-264532-xfb94lq8	47	19	also	also	RB
cord-264532-xfb94lq8	47	20	results	result	VBZ
cord-264532-xfb94lq8	47	21	in	in	IN
cord-264532-xfb94lq8	47	22	higher	high	JJR
cord-264532-xfb94lq8	47	23	virulence	virulence	NN
cord-264532-xfb94lq8	47	24	because	because	IN
cord-264532-xfb94lq8	47	25	of	of	IN
cord-264532-xfb94lq8	47	26	an	an	DT
cord-264532-xfb94lq8	47	27	assumed	assumed	JJ
cord-264532-xfb94lq8	47	28	trade	trade	NN
cord-264532-xfb94lq8	47	29	-	-	HYPH
cord-264532-xfb94lq8	47	30	off	off	NN
cord-264532-xfb94lq8	47	31	between	between	IN
cord-264532-xfb94lq8	47	32	transmission	transmission	NN
cord-264532-xfb94lq8	47	33	and	and	CC
cord-264532-xfb94lq8	47	34	virulence	virulence	NN
cord-264532-xfb94lq8	47	35	.	.	.
cord-264532-xfb94lq8	48	1	The	the	DT
cord-264532-xfb94lq8	48	2	Lenski	Lenski	NNP
cord-264532-xfb94lq8	48	3	and	and	CC
cord-264532-xfb94lq8	48	4	May	May	NNP
cord-264532-xfb94lq8	48	5	model	model	NN
cord-264532-xfb94lq8	48	6	lays	lay	VBZ
cord-264532-xfb94lq8	48	7	the	the	DT
cord-264532-xfb94lq8	48	8	foundation	foundation	NN
cord-264532-xfb94lq8	48	9	for	for	IN
cord-264532-xfb94lq8	48	10	the	the	DT
cord-264532-xfb94lq8	48	11	argument	argument	NN
cord-264532-xfb94lq8	48	12	we	-PRON-	PRP
cord-264532-xfb94lq8	48	13	develop	develop	VBP
cord-264532-xfb94lq8	48	14	here	here	RB
cord-264532-xfb94lq8	48	15	,	,	,
cord-264532-xfb94lq8	48	16	so	so	RB
cord-264532-xfb94lq8	48	17	we	-PRON-	PRP
cord-264532-xfb94lq8	48	18	offer	offer	VBP
cord-264532-xfb94lq8	48	19	a	a	DT
cord-264532-xfb94lq8	48	20	simple	simple	JJ
cord-264532-xfb94lq8	48	21	version	version	NN
cord-264532-xfb94lq8	48	22	in	in	IN
cord-264532-xfb94lq8	48	23	the	the	DT
cord-264532-xfb94lq8	48	24	form	form	NN
cord-264532-xfb94lq8	48	25	of	of	IN
cord-264532-xfb94lq8	48	26	an	an	DT
cord-264532-xfb94lq8	48	27	'	'	``
cord-264532-xfb94lq8	48	28	SI	SI	NNP
cord-264532-xfb94lq8	48	29	'	'	''
cord-264532-xfb94lq8	48	30	model	model	NN
cord-264532-xfb94lq8	48	31	.	.	.
cord-264532-xfb94lq8	49	1	For	for	IN
cord-264532-xfb94lq8	49	2	a	a	DT
cord-264532-xfb94lq8	49	3	constant	constant	JJ
cord-264532-xfb94lq8	49	4	density	density	NN
cord-264532-xfb94lq8	49	5	of	of	IN
cord-264532-xfb94lq8	49	6	susceptible	susceptible	JJ
cord-264532-xfb94lq8	49	7	hosts	host	NNS
cord-264532-xfb94lq8	49	8	,	,	,
cord-264532-xfb94lq8	49	9	S	S	NNP
cord-264532-xfb94lq8	49	10	,	,	,
cord-264532-xfb94lq8	49	11	and	and	CC
cord-264532-xfb94lq8	49	12	an	an	DT
cord-264532-xfb94lq8	49	13	absence	absence	NN
cord-264532-xfb94lq8	49	14	of	of	IN
cord-264532-xfb94lq8	49	15	genetic	genetic	JJ
cord-264532-xfb94lq8	49	16	variation	variation	NN
cord-264532-xfb94lq8	49	17	in	in	IN
cord-264532-xfb94lq8	49	18	parasite	parasite	NN
cord-264532-xfb94lq8	49	19	and	and	CC
cord-264532-xfb94lq8	49	20	host	host	NN
cord-264532-xfb94lq8	49	21	parameters	parameter	NNS
cord-264532-xfb94lq8	49	22	,	,	,
cord-264532-xfb94lq8	49	23	the	the	DT
cord-264532-xfb94lq8	49	24	epidemic	epidemic	NN
cord-264532-xfb94lq8	49	25	is	be	VBZ
cord-264532-xfb94lq8	49	26	characterized	characterize	VBN
cord-264532-xfb94lq8	49	27	by	by	IN
cord-264532-xfb94lq8	49	28	one	one	CD
cord-264532-xfb94lq8	49	29	equation	equation	NN
cord-264532-xfb94lq8	49	30	for	for	IN
cord-264532-xfb94lq8	49	31	the	the	DT
cord-264532-xfb94lq8	49	32	change	change	NN
cord-264532-xfb94lq8	49	33	in	in	IN
cord-264532-xfb94lq8	49	34	abundance	abundance	NN
cord-264532-xfb94lq8	49	35	of	of	IN
cord-264532-xfb94lq8	49	36	infected	infected	JJ
cord-264532-xfb94lq8	49	37	individuals	individual	NNS
cord-264532-xfb94lq8	49	38	,	,	,
cord-264532-xfb94lq8	49	39	I	-PRON-	PRP
cord-264532-xfb94lq8	49	40	:	:	:
cord-264532-xfb94lq8	49	41	where	where	WRB
cord-264532-xfb94lq8	49	42	b	b	NN
cord-264532-xfb94lq8	49	43	is	be	VBZ
cord-264532-xfb94lq8	49	44	the	the	DT
cord-264532-xfb94lq8	49	45	transmission	transmission	NN
cord-264532-xfb94lq8	49	46	rate	rate	NN
cord-264532-xfb94lq8	49	47	,	,	,
cord-264532-xfb94lq8	49	48	and	and	CC
cord-264532-xfb94lq8	49	49	d	d	NN
cord-264532-xfb94lq8	49	50	is	be	VBZ
cord-264532-xfb94lq8	49	51	the	the	DT
cord-264532-xfb94lq8	49	52	combined	combine	VBN
cord-264532-xfb94lq8	49	53	death	death	NN
cord-264532-xfb94lq8	49	54	rate	rate	NN
cord-264532-xfb94lq8	49	55	of	of	IN
cord-264532-xfb94lq8	49	56	infected	infected	JJ
cord-264532-xfb94lq8	49	57	individuals	individual	NNS
cord-264532-xfb94lq8	49	58	[	[	-LRB-
cord-264532-xfb94lq8	49	59	d	d	NNP
cord-264532-xfb94lq8	49	60	is	be	VBZ
cord-264532-xfb94lq8	49	61	the	the	DT
cord-264532-xfb94lq8	49	62	sum	sum	NN
cord-264532-xfb94lq8	49	63	of	of	IN
cord-264532-xfb94lq8	49	64	an	an	DT
cord-264532-xfb94lq8	49	65	intrinsic	intrinsic	JJ
cord-264532-xfb94lq8	49	66	host	host	NN
cord-264532-xfb94lq8	49	67	mortality	mortality	NN
cord-264532-xfb94lq8	49	68	rate	rate	NN
cord-264532-xfb94lq8	49	69	and	and	CC
cord-264532-xfb94lq8	49	70	a	a	DT
cord-264532-xfb94lq8	49	71	virulence	virulence	NN
cord-264532-xfb94lq8	49	72	,	,	,
cord-264532-xfb94lq8	49	73	or	or	CC
cord-264532-xfb94lq8	49	74	parasiteinduced	parasiteinduced	JJ
cord-264532-xfb94lq8	49	75	mortality	mortality	NN
cord-264532-xfb94lq8	49	76	,	,	,
cord-264532-xfb94lq8	49	77	and	and	CC
cord-264532-xfb94lq8	49	78	aside	aside	RB
cord-264532-xfb94lq8	49	79	from	from	IN
cord-264532-xfb94lq8	49	80	this	this	DT
cord-264532-xfb94lq8	49	81	difference	difference	NN
cord-264532-xfb94lq8	49	82	,	,	,
cord-264532-xfb94lq8	49	83	equation	equation	NN
cord-264532-xfb94lq8	49	84	(	(	-LRB-
cord-264532-xfb94lq8	49	85	1a	1a	NN
cord-264532-xfb94lq8	49	86	)	)	-RRB-
cord-264532-xfb94lq8	49	87	is	be	VBZ
cord-264532-xfb94lq8	49	88	otherwise	otherwise	RB
cord-264532-xfb94lq8	49	89	the	the	DT
cord-264532-xfb94lq8	49	90	same	same	JJ
cord-264532-xfb94lq8	49	91	as	as	IN
cord-264532-xfb94lq8	49	92	equation	equation	NN
cord-264532-xfb94lq8	49	93	(	(	-LRB-
cord-264532-xfb94lq8	49	94	2	2	CD
cord-264532-xfb94lq8	49	95	)	)	-RRB-
cord-264532-xfb94lq8	49	96	in	in	IN
cord-264532-xfb94lq8	49	97	Lenski	Lenski	NNP
cord-264532-xfb94lq8	49	98	and	and	CC
cord-264532-xfb94lq8	49	99	May	May	NNP
cord-264532-xfb94lq8	49	100	(	(	-LRB-
cord-264532-xfb94lq8	49	101	1994	1994	CD
cord-264532-xfb94lq8	49	102	)	)	-RRB-
cord-264532-xfb94lq8	49	103	and	and	CC
cord-264532-xfb94lq8	49	104	Gilchrist	Gilchrist	NNP
cord-264532-xfb94lq8	49	105	and	and	CC
cord-264532-xfb94lq8	49	106	Coombs	Coombs	NNP
cord-264532-xfb94lq8	49	107	(	(	-LRB-
cord-264532-xfb94lq8	49	108	2006	2006	CD
cord-264532-xfb94lq8	49	109	)	)	-RRB-
cord-264532-xfb94lq8	49	110	]	]	-RRB-
cord-264532-xfb94lq8	49	111	.	.	.
cord-264532-xfb94lq8	50	1	The	the	DT
cord-264532-xfb94lq8	50	2	total	total	JJ
cord-264532-xfb94lq8	50	3	host	host	NN
cord-264532-xfb94lq8	50	4	population	population	NN
cord-264532-xfb94lq8	50	5	is	be	VBZ
cord-264532-xfb94lq8	50	6	simply	simply	RB
cord-264532-xfb94lq8	50	7	N	n	NN
cord-264532-xfb94lq8	50	8	=	=	SYM
cord-264532-xfb94lq8	50	9	S	s	NN
cord-264532-xfb94lq8	50	10	+	+	CC
cord-264532-xfb94lq8	51	1	I.	I.	NNP
cord-264532-xfb94lq8	51	2	A	a	DT
cord-264532-xfb94lq8	51	3	constant	constant	JJ
cord-264532-xfb94lq8	51	4	density	density	NN
cord-264532-xfb94lq8	51	5	of	of	IN
cord-264532-xfb94lq8	51	6	susceptible	susceptible	JJ
cord-264532-xfb94lq8	51	7	hosts	host	NNS
cord-264532-xfb94lq8	51	8	is	be	VBZ
cord-264532-xfb94lq8	51	9	reasonable	reasonable	JJ
cord-264532-xfb94lq8	51	10	whenever	whenever	WRB
cord-264532-xfb94lq8	51	11	the	the	DT
cord-264532-xfb94lq8	51	12	infection	infection	NN
cord-264532-xfb94lq8	51	13	is	be	VBZ
cord-264532-xfb94lq8	51	14	so	so	RB
cord-264532-xfb94lq8	51	15	rare	rare	JJ
cord-264532-xfb94lq8	51	16	that	that	IN
cord-264532-xfb94lq8	51	17	most	most	JJS
cord-264532-xfb94lq8	51	18	hosts	host	NNS
cord-264532-xfb94lq8	51	19	have	have	VBP
cord-264532-xfb94lq8	51	20	not	not	RB
cord-264532-xfb94lq8	51	21	yet	yet	RB
cord-264532-xfb94lq8	51	22	been	be	VBN
cord-264532-xfb94lq8	51	23	infected	infect	VBN
cord-264532-xfb94lq8	51	24	.	.	.
cord-264532-xfb94lq8	52	1	The	the	DT
cord-264532-xfb94lq8	52	2	per	per	IN
cord-264532-xfb94lq8	52	3	capita	capita	NN
cord-264532-xfb94lq8	52	4	rate	rate	NN
cord-264532-xfb94lq8	52	5	of	of	IN
cord-264532-xfb94lq8	52	6	pathogen	pathogen	NN
cord-264532-xfb94lq8	52	7	spread	spread	NN
cord-264532-xfb94lq8	52	8	is	be	VBZ
cord-264532-xfb94lq8	52	9	then	then	RB
cord-264532-xfb94lq8	52	10	:	:	:
cord-264532-xfb94lq8	52	11	This	this	DT
cord-264532-xfb94lq8	52	12	quantity	quantity	NN
cord-264532-xfb94lq8	52	13	is	be	VBZ
cord-264532-xfb94lq8	52	14	a	a	DT
cord-264532-xfb94lq8	52	15	measure	measure	NN
cord-264532-xfb94lq8	52	16	of	of	IN
cord-264532-xfb94lq8	52	17	parasite	parasite	JJ
cord-264532-xfb94lq8	52	18	fitness	fitness	NN
cord-264532-xfb94lq8	52	19	in	in	IN
cord-264532-xfb94lq8	52	20	the	the	DT
cord-264532-xfb94lq8	52	21	epidemic	epidemic	NN
cord-264532-xfb94lq8	52	22	(	(	-LRB-
cord-264532-xfb94lq8	52	23	a	a	DT
cord-264532-xfb94lq8	52	24	type	type	NN
cord-264532-xfb94lq8	52	25	of	of	IN
cord-264532-xfb94lq8	52	26	invasion	invasion	NN
cord-264532-xfb94lq8	52	27	fitness	fitness	NN
cord-264532-xfb94lq8	52	28	,	,	,
cord-264532-xfb94lq8	52	29	Metz	Metz	NNP
cord-264532-xfb94lq8	52	30	et	et	NNP
cord-264532-xfb94lq8	52	31	al	al	NNP
cord-264532-xfb94lq8	52	32	.	.	NNP
cord-264532-xfb94lq8	52	33	1992	1992	CD
cord-264532-xfb94lq8	52	34	)	)	-RRB-
cord-264532-xfb94lq8	52	35	,	,	,
cord-264532-xfb94lq8	52	36	because	because	IN
cord-264532-xfb94lq8	52	37	it	-PRON-	PRP
cord-264532-xfb94lq8	52	38	defines	define	VBZ
cord-264532-xfb94lq8	52	39	how	how	WRB
cord-264532-xfb94lq8	52	40	rapidly	rapidly	RB
cord-264532-xfb94lq8	52	41	the	the	DT
cord-264532-xfb94lq8	52	42	parasite	parasite	NN
cord-264532-xfb94lq8	52	43	spreads	spread	VBZ
cord-264532-xfb94lq8	52	44	;	;	:
cord-264532-xfb94lq8	52	45	indeed	indeed	RB
cord-264532-xfb94lq8	52	46	,	,	,
cord-264532-xfb94lq8	52	47	the	the	DT
cord-264532-xfb94lq8	52	48	quantity	quantity	NN
cord-264532-xfb94lq8	52	49	on	on	IN
cord-264532-xfb94lq8	52	50	the	the	DT
cord-264532-xfb94lq8	52	51	right	right	NN
cord-264532-xfb94lq8	52	52	of	of	IN
cord-264532-xfb94lq8	52	53	equality	equality	NN
cord-264532-xfb94lq8	52	54	(	(	-LRB-
cord-264532-xfb94lq8	52	55	1b	1b	NN
cord-264532-xfb94lq8	52	56	)	)	-RRB-
cord-264532-xfb94lq8	52	57	is	be	VBZ
cord-264532-xfb94lq8	52	58	the	the	DT
cord-264532-xfb94lq8	52	59	intrinsic	intrinsic	JJ
cord-264532-xfb94lq8	52	60	rate	rate	NN
cord-264532-xfb94lq8	52	61	of	of	IN
cord-264532-xfb94lq8	52	62	increase	increase	NN
cord-264532-xfb94lq8	52	63	of	of	IN
cord-264532-xfb94lq8	52	64	I.	i.	NN
cord-264532-xfb94lq8	53	1	The	the	DT
cord-264532-xfb94lq8	53	2	rate	rate	NN
cord-264532-xfb94lq8	53	3	of	of	IN
cord-264532-xfb94lq8	53	4	spread	spread	NN
cord-264532-xfb94lq8	53	5	is	be	VBZ
cord-264532-xfb94lq8	53	6	a	a	DT
cord-264532-xfb94lq8	53	7	function	function	NN
cord-264532-xfb94lq8	53	8	of	of	IN
cord-264532-xfb94lq8	53	9	parasite	parasite	NN
cord-264532-xfb94lq8	53	10	transmission	transmission	NN
cord-264532-xfb94lq8	53	11	(	(	-LRB-
cord-264532-xfb94lq8	53	12	b	b	NN
cord-264532-xfb94lq8	53	13	)	)	-RRB-
cord-264532-xfb94lq8	53	14	and	and	CC
cord-264532-xfb94lq8	53	15	the	the	DT
cord-264532-xfb94lq8	53	16	death	death	NN
cord-264532-xfb94lq8	53	17	rate	rate	NN
cord-264532-xfb94lq8	53	18	of	of	IN
cord-264532-xfb94lq8	53	19	infected	infected	JJ
cord-264532-xfb94lq8	53	20	individuals	individual	NNS
cord-264532-xfb94lq8	53	21	(	(	-LRB-
cord-264532-xfb94lq8	53	22	d	d	NNP
cord-264532-xfb94lq8	53	23	)	)	-RRB-
cord-264532-xfb94lq8	53	24	,	,	,
cord-264532-xfb94lq8	53	25	two	two	CD
cord-264532-xfb94lq8	53	26	parameters	parameter	NNS
cord-264532-xfb94lq8	53	27	that	that	WDT
cord-264532-xfb94lq8	53	28	are	be	VBP
cord-264532-xfb94lq8	53	29	typically	typically	RB
cord-264532-xfb94lq8	53	30	assumed	assume	VBN
cord-264532-xfb94lq8	53	31	to	to	TO
cord-264532-xfb94lq8	53	32	be	be	VB
cord-264532-xfb94lq8	53	33	subject	subject	JJ
cord-264532-xfb94lq8	53	34	to	to	IN
cord-264532-xfb94lq8	53	35	a	a	DT
cord-264532-xfb94lq8	53	36	trade	trade	NN
cord-264532-xfb94lq8	53	37	-	-	HYPH
cord-264532-xfb94lq8	53	38	off	off	RP
cord-264532-xfb94lq8	53	39	boundary	boundary	NN
cord-264532-xfb94lq8	54	1	(	(	-LRB-
cord-264532-xfb94lq8	54	2	Fig	Fig	NNP
cord-264532-xfb94lq8	54	3	.	.	.
cord-264532-xfb94lq8	54	4	1	1	CD
cord-264532-xfb94lq8	54	5	top	top	NN
cord-264532-xfb94lq8	54	6	;	;	:
cord-264532-xfb94lq8	54	7	Ebert	Ebert	NNP
cord-264532-xfb94lq8	54	8	and	and	CC
cord-264532-xfb94lq8	54	9	Bull	Bull	NNP
cord-264532-xfb94lq8	54	10	2003	2003	CD
cord-264532-xfb94lq8	54	11	)	)	-RRB-
cord-264532-xfb94lq8	54	12	.	.	.
cord-264532-xfb94lq8	55	1	A	a	DT
cord-264532-xfb94lq8	55	2	trade	trade	NN
cord-264532-xfb94lq8	55	3	-	-	HYPH
cord-264532-xfb94lq8	55	4	off	off	NN
cord-264532-xfb94lq8	55	5	means	mean	VBZ
cord-264532-xfb94lq8	55	6	that	that	IN
cord-264532-xfb94lq8	55	7	the	the	DT
cord-264532-xfb94lq8	55	8	parasite	parasite	NN
cord-264532-xfb94lq8	55	9	can	can	MD
cord-264532-xfb94lq8	55	10	not	not	RB
cord-264532-xfb94lq8	55	11	increase	increase	VB
cord-264532-xfb94lq8	55	12	b	b	NN
cord-264532-xfb94lq8	55	13	without	without	IN
cord-264532-xfb94lq8	55	14	incurring	incur	VBG
cord-264532-xfb94lq8	55	15	increasing	increase	VBG
cord-264532-xfb94lq8	55	16	death	death	NN
cord-264532-xfb94lq8	55	17	rates	rate	NNS
cord-264532-xfb94lq8	55	18	(	(	-LRB-
cord-264532-xfb94lq8	55	19	d	d	NNP
cord-264532-xfb94lq8	55	20	)	)	-RRB-
cord-264532-xfb94lq8	55	21	,	,	,
cord-264532-xfb94lq8	55	22	although	although	IN
cord-264532-xfb94lq8	55	23	a	a	DT
cord-264532-xfb94lq8	55	24	more	more	RBR
cord-264532-xfb94lq8	55	25	stringent	stringent	JJ
cord-264532-xfb94lq8	55	26	criterion	criterion	NN
cord-264532-xfb94lq8	55	27	on	on	IN
cord-264532-xfb94lq8	55	28	the	the	DT
cord-264532-xfb94lq8	55	29	trade	trade	NN
cord-264532-xfb94lq8	55	30	-	-	HYPH
cord-264532-xfb94lq8	55	31	off	off	NN
cord-264532-xfb94lq8	55	32	,	,	,
cord-264532-xfb94lq8	55	33	such	such	JJ
cord-264532-xfb94lq8	55	34	as	as	IN
cord-264532-xfb94lq8	55	35	the	the	DT
cord-264532-xfb94lq8	55	36	concavity	concavity	NN
cord-264532-xfb94lq8	55	37	used	use	VBN
cord-264532-xfb94lq8	55	38	here	here	RB
cord-264532-xfb94lq8	55	39	,	,	,
cord-264532-xfb94lq8	55	40	is	be	VBZ
cord-264532-xfb94lq8	55	41	required	require	VBN
cord-264532-xfb94lq8	55	42	to	to	TO
cord-264532-xfb94lq8	55	43	select	select	VB
cord-264532-xfb94lq8	55	44	intermediate	intermediate	JJ
cord-264532-xfb94lq8	55	45	levels	level	NNS
cord-264532-xfb94lq8	55	46	of	of	IN
cord-264532-xfb94lq8	55	47	virulence	virulence	NN
cord-264532-xfb94lq8	55	48	(	(	-LRB-
cord-264532-xfb94lq8	55	49	Sasaki	Sasaki	NNP
cord-264532-xfb94lq8	55	50	and	and	CC
cord-264532-xfb94lq8	55	51	Iwasa	Iwasa	NNP
cord-264532-xfb94lq8	55	52	1991	1991	CD
cord-264532-xfb94lq8	55	53	)	)	-RRB-
cord-264532-xfb94lq8	55	54	.	.	.
cord-264532-xfb94lq8	56	1	Following	follow	VBG
cord-264532-xfb94lq8	56	2	Lenski	Lenski	NNP
cord-264532-xfb94lq8	56	3	and	and	CC
cord-264532-xfb94lq8	56	4	May	May	NNP
cord-264532-xfb94lq8	56	5	(	(	-LRB-
cord-264532-xfb94lq8	56	6	1994	1994	CD
cord-264532-xfb94lq8	56	7	)	)	-RRB-
cord-264532-xfb94lq8	56	8	for	for	IN
cord-264532-xfb94lq8	56	9	now	now	RB
cord-264532-xfb94lq8	56	10	,	,	,
cord-264532-xfb94lq8	56	11	we	-PRON-	PRP
cord-264532-xfb94lq8	56	12	let	let	VBP
cord-264532-xfb94lq8	56	13	d	d	NN
cord-264532-xfb94lq8	56	14	be	be	VB
cord-264532-xfb94lq8	56	15	the	the	DT
cord-264532-xfb94lq8	56	16	sum	sum	NN
cord-264532-xfb94lq8	56	17	of	of	IN
cord-264532-xfb94lq8	56	18	a	a	DT
cord-264532-xfb94lq8	56	19	constant	constant	JJ
cord-264532-xfb94lq8	56	20	host	host	NN
cord-264532-xfb94lq8	56	21	mortality	mortality	NN
cord-264532-xfb94lq8	56	22	plus	plus	CC
cord-264532-xfb94lq8	56	23	virulence	virulence	NN
cord-264532-xfb94lq8	56	24	;	;	:
cord-264532-xfb94lq8	56	25	we	-PRON-	PRP
cord-264532-xfb94lq8	56	26	will	will	MD
cord-264532-xfb94lq8	56	27	refer	refer	VB
cord-264532-xfb94lq8	56	28	to	to	IN
cord-264532-xfb94lq8	56	29	d	d	NNP
cord-264532-xfb94lq8	56	30	as	as	RB
cord-264532-xfb94lq8	56	31	simply	simply	RB
cord-264532-xfb94lq8	56	32	virulence	virulence	NN
cord-264532-xfb94lq8	56	33	without	without	IN
cord-264532-xfb94lq8	56	34	loss	loss	NN
cord-264532-xfb94lq8	56	35	of	of	IN
cord-264532-xfb94lq8	56	36	generality	generality	NN
cord-264532-xfb94lq8	56	37	.	.	.
cord-264532-xfb94lq8	57	1	Given	give	VBN
cord-264532-xfb94lq8	57	2	that	that	IN
cord-264532-xfb94lq8	57	3	the	the	DT
cord-264532-xfb94lq8	57	4	parasite	parasite	NN
cord-264532-xfb94lq8	57	5	is	be	VBZ
cord-264532-xfb94lq8	57	6	confined	confine	VBN
cord-264532-xfb94lq8	57	7	to	to	IN
cord-264532-xfb94lq8	57	8	a	a	DT
cord-264532-xfb94lq8	57	9	trade	trade	NN
cord-264532-xfb94lq8	57	10	-	-	HYPH
cord-264532-xfb94lq8	57	11	off	off	NN
cord-264532-xfb94lq8	57	12	but	but	CC
cord-264532-xfb94lq8	57	13	is	be	VBZ
cord-264532-xfb94lq8	57	14	allowed	allow	VBN
cord-264532-xfb94lq8	57	15	to	to	TO
cord-264532-xfb94lq8	57	16	evolve	evolve	VB
cord-264532-xfb94lq8	57	17	along	along	IN
cord-264532-xfb94lq8	57	18	the	the	DT
cord-264532-xfb94lq8	57	19	trade	trade	NN
cord-264532-xfb94lq8	57	20	-	-	HYPH
cord-264532-xfb94lq8	57	21	off	off	NN
cord-264532-xfb94lq8	57	22	,	,	,
cord-264532-xfb94lq8	57	23	the	the	DT
cord-264532-xfb94lq8	57	24	combination	combination	NN
cord-264532-xfb94lq8	57	25	of	of	IN
cord-264532-xfb94lq8	57	26	b	b	NN
cord-264532-xfb94lq8	57	27	and	and	CC
cord-264532-xfb94lq8	57	28	d	d	XX
cord-264532-xfb94lq8	57	29	maximizing	maximize	VBG
cord-264532-xfb94lq8	57	30	parasite	parasite	NN
cord-264532-xfb94lq8	57	31	fitness	fitness	NN
cord-264532-xfb94lq8	57	32	during	during	IN
cord-264532-xfb94lq8	57	33	invasion	invasion	NN
cord-264532-xfb94lq8	57	34	is	be	VBZ
cord-264532-xfb94lq8	57	35	given	give	VBN
cord-264532-xfb94lq8	57	36	by	by	IN
cord-264532-xfb94lq8	57	37	which	which	WDT
cord-264532-xfb94lq8	57	38	is	be	VBZ
cord-264532-xfb94lq8	57	39	graphically	graphically	RB
cord-264532-xfb94lq8	57	40	represented	represent	VBN
cord-264532-xfb94lq8	57	41	as	as	IN
cord-264532-xfb94lq8	57	42	the	the	DT
cord-264532-xfb94lq8	57	43	dot	dot	NN
cord-264532-xfb94lq8	57	44	along	along	IN
cord-264532-xfb94lq8	57	45	the	the	DT
cord-264532-xfb94lq8	57	46	trade	trade	NN
cord-264532-xfb94lq8	57	47	-	-	HYPH
cord-264532-xfb94lq8	57	48	off	off	RP
cord-264532-xfb94lq8	57	49	function	function	NN
cord-264532-xfb94lq8	57	50	whose	whose	WP$
cord-264532-xfb94lq8	57	51	slope	slope	NN
cord-264532-xfb94lq8	57	52	is	be	VBZ
cord-264532-xfb94lq8	57	53	S	S	NNP
cord-264532-xfb94lq8	57	54	(	(	-LRB-
cord-264532-xfb94lq8	57	55	Fig	Fig	NNP
cord-264532-xfb94lq8	57	56	.	.	NNP
cord-264532-xfb94lq8	57	57	1	1	CD
cord-264532-xfb94lq8	57	58	,	,	,
cord-264532-xfb94lq8	57	59	bottom	bottom	NN
cord-264532-xfb94lq8	57	60	;	;	,
cord-264532-xfb94lq8	57	61	shown	show	VBN
cord-264532-xfb94lq8	57	62	in	in	IN
cord-264532-xfb94lq8	57	63	comparison	comparison	NN
cord-264532-xfb94lq8	57	64	to	to	IN
cord-264532-xfb94lq8	57	65	the	the	DT
cord-264532-xfb94lq8	57	66	R	r	NN
cord-264532-xfb94lq8	57	67	0	0	CD
cord-264532-xfb94lq8	57	68	maximum	maximum	NN
cord-264532-xfb94lq8	57	69	)	)	-RRB-
cord-264532-xfb94lq8	57	70	.	.	.
cord-264532-xfb94lq8	58	1	In	in	IN
cord-264532-xfb94lq8	58	2	prior	prior	JJ
cord-264532-xfb94lq8	58	3	work	work	NN
cord-264532-xfb94lq8	58	4	,	,	,
cord-264532-xfb94lq8	58	5	the	the	DT
cord-264532-xfb94lq8	58	6	fitness	fitness	NN
cord-264532-xfb94lq8	58	7	'	'	``
cord-264532-xfb94lq8	58	8	optimum	optimum	NN
cord-264532-xfb94lq8	58	9	'	'	''
cord-264532-xfb94lq8	58	10	found	find	VBN
cord-264532-xfb94lq8	58	11	in	in	IN
cord-264532-xfb94lq8	58	12	this	this	DT
cord-264532-xfb94lq8	58	13	way	way	NN
cord-264532-xfb94lq8	58	14	is	be	VBZ
cord-264532-xfb94lq8	58	15	usually	usually	RB
cord-264532-xfb94lq8	58	16	regarded	regard	VBN
cord-264532-xfb94lq8	58	17	as	as	IN
cord-264532-xfb94lq8	58	18	the	the	DT
cord-264532-xfb94lq8	58	19	phenotype	phenotype	NN
cord-264532-xfb94lq8	58	20	that	that	IN
cord-264532-xfb94lq8	58	21	the	the	DT
cord-264532-xfb94lq8	58	22	parasite	parasite	NN
cord-264532-xfb94lq8	58	23	will	will	MD
cord-264532-xfb94lq8	58	24	evolve	evolve	VB
cord-264532-xfb94lq8	58	25	toward	toward	IN
cord-264532-xfb94lq8	58	26	(	(	-LRB-
cord-264532-xfb94lq8	58	27	and	and	CC
cord-264532-xfb94lq8	58	28	will	will	MD
cord-264532-xfb94lq8	58	29	ultimately	ultimately	RB
cord-264532-xfb94lq8	58	30	attain	attain	VB
cord-264532-xfb94lq8	58	31	,	,	,
cord-264532-xfb94lq8	58	32	if	if	IN
cord-264532-xfb94lq8	58	33	the	the	DT
cord-264532-xfb94lq8	58	34	environment	environment	NN
cord-264532-xfb94lq8	58	35	does	do	VBZ
cord-264532-xfb94lq8	58	36	not	not	RB
cord-264532-xfb94lq8	58	37	change	change	VB
cord-264532-xfb94lq8	58	38	)	)	-RRB-
cord-264532-xfb94lq8	58	39	.	.	.
cord-264532-xfb94lq8	59	1	As	as	IN
cord-264532-xfb94lq8	59	2	demonstrated	demonstrate	VBN
cord-264532-xfb94lq8	59	3	by	by	IN
cord-264532-xfb94lq8	59	4	Lenski	Lenski	NNP
cord-264532-xfb94lq8	59	5	and	and	CC
cord-264532-xfb94lq8	59	6	May	May	NNP
cord-264532-xfb94lq8	59	7	(	(	-LRB-
cord-264532-xfb94lq8	59	8	1994	1994	CD
cord-264532-xfb94lq8	59	9	)	)	-RRB-
cord-264532-xfb94lq8	59	10	,	,	,
cord-264532-xfb94lq8	59	11	this	this	DT
cord-264532-xfb94lq8	59	12	optimum	optimum	JJ
cord-264532-xfb94lq8	59	13	changes	change	NNS
cord-264532-xfb94lq8	59	14	as	as	IN
cord-264532-xfb94lq8	59	15	the	the	DT
cord-264532-xfb94lq8	59	16	density	density	NN
cord-264532-xfb94lq8	59	17	of	of	IN
cord-264532-xfb94lq8	59	18	susceptible	susceptible	JJ
cord-264532-xfb94lq8	59	19	hosts	host	NNS
cord-264532-xfb94lq8	59	20	is	be	VBZ
cord-264532-xfb94lq8	59	21	reduced	reduce	VBN
cord-264532-xfb94lq8	59	22	by	by	IN
cord-264532-xfb94lq8	59	23	the	the	DT
cord-264532-xfb94lq8	59	24	parasite	parasite	NN
cord-264532-xfb94lq8	59	25	,	,	,
cord-264532-xfb94lq8	59	26	ultimately	ultimately	RB
cord-264532-xfb94lq8	59	27	coinciding	coincide	VBG
cord-264532-xfb94lq8	59	28	with	with	IN
cord-264532-xfb94lq8	59	29	the	the	DT
cord-264532-xfb94lq8	59	30	R	r	NN
cord-264532-xfb94lq8	59	31	0	0	CD
cord-264532-xfb94lq8	59	32	maximization	maximization	NN
cord-264532-xfb94lq8	59	33	(	(	-LRB-
cord-264532-xfb94lq8	59	34	Fig	fig	NN
cord-264532-xfb94lq8	59	35	.	.	.
cord-264532-xfb94lq8	59	36	1	1	CD
cord-264532-xfb94lq8	59	37	)	)	-RRB-
cord-264532-xfb94lq8	59	38	.	.	.
cord-264532-xfb94lq8	60	1	Thus	thus	RB
cord-264532-xfb94lq8	60	2	,	,	,
cord-264532-xfb94lq8	60	3	the	the	DT
cord-264532-xfb94lq8	60	4	optimum	optimum	JJ
cord-264532-xfb94lq8	60	5	stops	stop	VBZ
cord-264532-xfb94lq8	60	6	changing	change	VBG
cord-264532-xfb94lq8	60	7	when	when	WRB
cord-264532-xfb94lq8	60	8	the	the	DT
cord-264532-xfb94lq8	60	9	epidemic	epidemic	NN
cord-264532-xfb94lq8	60	10	is	be	VBZ
cord-264532-xfb94lq8	60	11	over	over	RB
cord-264532-xfb94lq8	60	12	and	and	CC
cord-264532-xfb94lq8	60	13	the	the	DT
cord-264532-xfb94lq8	60	14	population	population	NN
cord-264532-xfb94lq8	60	15	has	have	VBZ
cord-264532-xfb94lq8	60	16	reached	reach	VBN
cord-264532-xfb94lq8	60	17	dynamic	dynamic	JJ
cord-264532-xfb94lq8	60	18	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	60	19	between	between	IN
cord-264532-xfb94lq8	60	20	host	host	NN
cord-264532-xfb94lq8	60	21	and	and	CC
cord-264532-xfb94lq8	60	22	parasite	parasite	NN
cord-264532-xfb94lq8	60	23	(	(	-LRB-
cord-264532-xfb94lq8	60	24	and	and	CC
cord-264532-xfb94lq8	60	25	parasite	parasite	JJ
cord-264532-xfb94lq8	60	26	virulence	virulence	NN
cord-264532-xfb94lq8	60	27	is	be	VBZ
cord-264532-xfb94lq8	60	28	optimal	optimal	JJ
cord-264532-xfb94lq8	60	29	)	)	-RRB-
cord-264532-xfb94lq8	60	30	.	.	.
cord-264532-xfb94lq8	61	1	Both	both	DT
cord-264532-xfb94lq8	61	2	prior	prior	JJ
cord-264532-xfb94lq8	61	3	perspectives	perspective	NNS
cord-264532-xfb94lq8	61	4	essentially	essentially	RB
cord-264532-xfb94lq8	61	5	restrict	restrict	VBP
cord-264532-xfb94lq8	61	6	evolution	evolution	NN
cord-264532-xfb94lq8	61	7	to	to	IN
cord-264532-xfb94lq8	61	8	the	the	DT
cord-264532-xfb94lq8	61	9	trade	trade	NN
cord-264532-xfb94lq8	61	10	-	-	HYPH
cord-264532-xfb94lq8	61	11	off	off	RP
cord-264532-xfb94lq8	61	12	function	function	NN
cord-264532-xfb94lq8	61	13	,	,	,
cord-264532-xfb94lq8	61	14	with	with	IN
cord-264532-xfb94lq8	61	15	an	an	DT
cord-264532-xfb94lq8	61	16	emphasis	emphasis	NN
cord-264532-xfb94lq8	61	17	on	on	IN
cord-264532-xfb94lq8	61	18	optima	optima	NNP
cord-264532-xfb94lq8	61	19	.	.	.
cord-264532-xfb94lq8	62	1	In	in	IN
cord-264532-xfb94lq8	62	2	the	the	DT
cord-264532-xfb94lq8	62	3	Lenski	Lenski	NNP
cord-264532-xfb94lq8	62	4	-	-	HYPH
cord-264532-xfb94lq8	62	5	May	May	NNP
cord-264532-xfb94lq8	62	6	model	model	NN
cord-264532-xfb94lq8	62	7	,	,	,
cord-264532-xfb94lq8	62	8	the	the	DT
cord-264532-xfb94lq8	62	9	optima	optima	NNP
cord-264532-xfb94lq8	62	10	are	be	VBP
cord-264532-xfb94lq8	62	11	temporary	temporary	JJ
cord-264532-xfb94lq8	62	12	,	,	,
cord-264532-xfb94lq8	62	13	changing	change	VBG
cord-264532-xfb94lq8	62	14	as	as	IN
cord-264532-xfb94lq8	62	15	the	the	DT
cord-264532-xfb94lq8	62	16	density	density	NN
cord-264532-xfb94lq8	62	17	of	of	IN
cord-264532-xfb94lq8	62	18	susceptible	susceptible	JJ
cord-264532-xfb94lq8	62	19	hosts	host	NNS
cord-264532-xfb94lq8	62	20	changes	change	NNS
cord-264532-xfb94lq8	62	21	.	.	.
cord-264532-xfb94lq8	63	1	Both	both	DT
cord-264532-xfb94lq8	63	2	prior	prior	JJ
cord-264532-xfb94lq8	63	3	perspectives	perspective	NNS
cord-264532-xfb94lq8	63	4	differ	differ	VBP
cord-264532-xfb94lq8	63	5	from	from	IN
cord-264532-xfb94lq8	63	6	a	a	DT
cord-264532-xfb94lq8	63	7	new	new	JJ
cord-264532-xfb94lq8	63	8	approach	approach	NN
cord-264532-xfb94lq8	63	9	that	that	WDT
cord-264532-xfb94lq8	63	10	incorporates	incorporate	VBZ
cord-264532-xfb94lq8	63	11	dynamics	dynamic	NNS
cord-264532-xfb94lq8	63	12	,	,	,
cord-264532-xfb94lq8	63	13	selection	selection	NN
cord-264532-xfb94lq8	63	14	and	and	CC
cord-264532-xfb94lq8	63	15	genetics	genetic	NNS
cord-264532-xfb94lq8	63	16	simultaneously	simultaneously	RB
cord-264532-xfb94lq8	63	17	(	(	-LRB-
cord-264532-xfb94lq8	63	18	Day	Day	NNP
cord-264532-xfb94lq8	63	19	and	and	CC
cord-264532-xfb94lq8	63	20	Proulx	Proulx	NNP
cord-264532-xfb94lq8	63	21	2004	2004	CD
cord-264532-xfb94lq8	63	22	;	;	:
cord-264532-xfb94lq8	63	23	Gandon	Gandon	NNP
cord-264532-xfb94lq8	63	24	2006	2006	CD
cord-264532-xfb94lq8	63	25	,	,	,
cord-264532-xfb94lq8	63	26	2007	2007	CD
cord-264532-xfb94lq8	63	27	)	)	-RRB-
cord-264532-xfb94lq8	63	28	.	.	.
cord-264532-xfb94lq8	64	1	This	this	DT
cord-264532-xfb94lq8	64	2	latter	latter	JJ
cord-264532-xfb94lq8	64	3	approach	approach	NN
cord-264532-xfb94lq8	64	4	allows	allow	VBZ
cord-264532-xfb94lq8	64	5	the	the	DT
cord-264532-xfb94lq8	64	6	virulence	virulence	NN
cord-264532-xfb94lq8	64	7	and	and	CC
cord-264532-xfb94lq8	64	8	transmission	transmission	NN
cord-264532-xfb94lq8	64	9	parameters	parameter	NNS
cord-264532-xfb94lq8	64	10	to	to	TO
cord-264532-xfb94lq8	64	11	vary	vary	VB
cord-264532-xfb94lq8	64	12	anywhere	anywhere	RB
cord-264532-xfb94lq8	64	13	within	within	IN
cord-264532-xfb94lq8	64	14	the	the	DT
cord-264532-xfb94lq8	64	15	zone	zone	NN
cord-264532-xfb94lq8	64	16	of	of	IN
cord-264532-xfb94lq8	64	17	attainable	attainable	JJ
cord-264532-xfb94lq8	64	18	phenotypes	phenotype	NNS
cord-264532-xfb94lq8	64	19	,	,	,
cord-264532-xfb94lq8	64	20	and	and	CC
cord-264532-xfb94lq8	64	21	it	-PRON-	PRP
cord-264532-xfb94lq8	64	22	maps	map	VBZ
cord-264532-xfb94lq8	64	23	changes	change	NNS
cord-264532-xfb94lq8	64	24	in	in	IN
cord-264532-xfb94lq8	64	25	the	the	DT
cord-264532-xfb94lq8	64	26	mean	mean	JJ
cord-264532-xfb94lq8	64	27	phenotypes	phenotype	NNS
cord-264532-xfb94lq8	64	28	as	as	IN
cord-264532-xfb94lq8	64	29	a	a	DT
cord-264532-xfb94lq8	64	30	function	function	NN
cord-264532-xfb94lq8	64	31	of	of	IN
cord-264532-xfb94lq8	64	32	selection	selection	NN
cord-264532-xfb94lq8	64	33	and	and	CC
cord-264532-xfb94lq8	64	34	of	of	IN
cord-264532-xfb94lq8	64	35	genetic	genetic	JJ
cord-264532-xfb94lq8	64	36	covariances	covariance	NNS
cord-264532-xfb94lq8	64	37	between	between	IN
cord-264532-xfb94lq8	64	38	the	the	DT
cord-264532-xfb94lq8	64	39	two	two	CD
cord-264532-xfb94lq8	64	40	traits	trait	NNS
cord-264532-xfb94lq8	64	41	.	.	.
cord-264532-xfb94lq8	65	1	The	the	DT
cord-264532-xfb94lq8	65	2	optima	optima	NNP
cord-264532-xfb94lq8	65	3	in	in	IN
cord-264532-xfb94lq8	65	4	this	this	DT
cord-264532-xfb94lq8	65	5	new	new	JJ
cord-264532-xfb94lq8	65	6	approach	approach	NN
cord-264532-xfb94lq8	65	7	are	be	VBP
cord-264532-xfb94lq8	65	8	not	not	RB
cord-264532-xfb94lq8	65	9	altered	alter	VBN
cord-264532-xfb94lq8	65	10	,	,	,
cord-264532-xfb94lq8	65	11	but	but	CC
cord-264532-xfb94lq8	65	12	the	the	DT
cord-264532-xfb94lq8	65	13	model	model	NN
cord-264532-xfb94lq8	65	14	is	be	VBZ
cord-264532-xfb94lq8	65	15	extended	extend	VBN
cord-264532-xfb94lq8	65	16	to	to	TO
cord-264532-xfb94lq8	65	17	include	include	VB
cord-264532-xfb94lq8	65	18	the	the	DT
cord-264532-xfb94lq8	65	19	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	65	20	and	and	CC
cord-264532-xfb94lq8	65	21	population	population	NN
cord-264532-xfb94lq8	65	22	dynamics	dynamic	NNS
cord-264532-xfb94lq8	65	23	.	.	.
cord-264532-xfb94lq8	66	1	This	this	DT
cord-264532-xfb94lq8	66	2	newer	new	JJR
cord-264532-xfb94lq8	66	3	method	method	NN
cord-264532-xfb94lq8	66	4	thus	thus	RB
cord-264532-xfb94lq8	66	5	subsumes	subsume	VBZ
cord-264532-xfb94lq8	66	6	the	the	DT
cord-264532-xfb94lq8	66	7	former	former	JJ
cord-264532-xfb94lq8	66	8	ones	one	NNS
cord-264532-xfb94lq8	66	9	.	.	.
cord-264532-xfb94lq8	67	1	Our	-PRON-	PRP$
cord-264532-xfb94lq8	67	2	goal	goal	NN
cord-264532-xfb94lq8	67	3	is	be	VBZ
cord-264532-xfb94lq8	67	4	to	to	TO
cord-264532-xfb94lq8	67	5	recognize	recognize	VB
cord-264532-xfb94lq8	67	6	a	a	DT
cord-264532-xfb94lq8	67	7	possible	possible	JJ
cord-264532-xfb94lq8	67	8	feature	feature	NN
cord-264532-xfb94lq8	67	9	of	of	IN
cord-264532-xfb94lq8	67	10	virulence	virulence	NN
cord-264532-xfb94lq8	67	11	evolution	evolution	NN
cord-264532-xfb94lq8	67	12	in	in	IN
cord-264532-xfb94lq8	67	13	parasites	parasite	NNS
cord-264532-xfb94lq8	67	14	that	that	WDT
cord-264532-xfb94lq8	67	15	newly	newly	RB
cord-264532-xfb94lq8	67	16	invade	invade	VBP
cord-264532-xfb94lq8	67	17	a	a	DT
cord-264532-xfb94lq8	67	18	host	host	NN
cord-264532-xfb94lq8	67	19	species	specie	NNS
cord-264532-xfb94lq8	67	20	.	.	.
cord-264532-xfb94lq8	68	1	More	more	RBR
cord-264532-xfb94lq8	68	2	importantly	importantly	RB
cord-264532-xfb94lq8	68	3	,	,	,
cord-264532-xfb94lq8	68	4	the	the	DT
cord-264532-xfb94lq8	68	5	same	same	JJ
cord-264532-xfb94lq8	68	6	feature	feature	NN
cord-264532-xfb94lq8	68	7	may	may	MD
cord-264532-xfb94lq8	68	8	apply	apply	VB
cord-264532-xfb94lq8	68	9	when	when	WRB
cord-264532-xfb94lq8	68	10	an	an	DT
cord-264532-xfb94lq8	68	11	established	establish	VBN
cord-264532-xfb94lq8	68	12	-	-	HYPH
cord-264532-xfb94lq8	68	13	parasite	parasite	NN
cord-264532-xfb94lq8	68	14	evolves	evolve	VBZ
cord-264532-xfb94lq8	68	15	to	to	TO
cord-264532-xfb94lq8	68	16	overcome	overcome	VB
cord-264532-xfb94lq8	68	17	host	host	NN
cord-264532-xfb94lq8	68	18	resistance	resistance	NN
cord-264532-xfb94lq8	68	19	or	or	CC
cord-264532-xfb94lq8	68	20	immunity	immunity	NN
cord-264532-xfb94lq8	68	21	.	.	.
cord-264532-xfb94lq8	69	1	The	the	DT
cord-264532-xfb94lq8	69	2	method	method	NN
cord-264532-xfb94lq8	69	3	we	-PRON-	PRP
cord-264532-xfb94lq8	69	4	use	use	VBP
cord-264532-xfb94lq8	69	5	in	in	IN
cord-264532-xfb94lq8	69	6	developing	develop	VBG
cord-264532-xfb94lq8	69	7	this	this	DT
cord-264532-xfb94lq8	69	8	argument	argument	NN
cord-264532-xfb94lq8	69	9	is	be	VBZ
cord-264532-xfb94lq8	69	10	compatible	compatible	JJ
cord-264532-xfb94lq8	69	11	with	with	IN
cord-264532-xfb94lq8	69	12	that	that	DT
cord-264532-xfb94lq8	69	13	of	of	IN
cord-264532-xfb94lq8	69	14	Day	Day	NNP
cord-264532-xfb94lq8	69	15	and	and	CC
cord-264532-xfb94lq8	69	16	Gandon	Gandon	NNP
cord-264532-xfb94lq8	69	17	(	(	-LRB-
cord-264532-xfb94lq8	69	18	2006	2006	CD
cord-264532-xfb94lq8	69	19	)	)	-RRB-
cord-264532-xfb94lq8	69	20	,	,	,
cord-264532-xfb94lq8	69	21	although	although	IN
cord-264532-xfb94lq8	69	22	our	-PRON-	PRP$
cord-264532-xfb94lq8	69	23	arguments	argument	NNS
cord-264532-xfb94lq8	69	24	are	be	VBP
cord-264532-xfb94lq8	69	25	presented	present	VBN
cord-264532-xfb94lq8	69	26	as	as	IN
cord-264532-xfb94lq8	69	27	if	if	IN
cord-264532-xfb94lq8	69	28	evolution	evolution	NN
cord-264532-xfb94lq8	69	29	proceeds	proceed	VBZ
cord-264532-xfb94lq8	69	30	via	via	IN
cord-264532-xfb94lq8	69	31	a	a	DT
cord-264532-xfb94lq8	69	32	succession	succession	NN
cord-264532-xfb94lq8	69	33	of	of	IN
cord-264532-xfb94lq8	69	34	successful	successful	JJ
cord-264532-xfb94lq8	69	35	mutants	mutant	NNS
cord-264532-xfb94lq8	69	36	rather	rather	RB
cord-264532-xfb94lq8	69	37	than	than	IN
cord-264532-xfb94lq8	69	38	by	by	IN
cord-264532-xfb94lq8	69	39	obeying	obey	VBG
cord-264532-xfb94lq8	69	40	covariances	covariance	NNS
cord-264532-xfb94lq8	69	41	of	of	IN
cord-264532-xfb94lq8	69	42	variation	variation	NN
cord-264532-xfb94lq8	69	43	that	that	WDT
cord-264532-xfb94lq8	69	44	is	be	VBZ
cord-264532-xfb94lq8	69	45	already	already	RB
cord-264532-xfb94lq8	69	46	present	present	JJ
cord-264532-xfb94lq8	69	47	.	.	.
cord-264532-xfb94lq8	70	1	Either	either	DT
cord-264532-xfb94lq8	70	2	type	type	NN
cord-264532-xfb94lq8	70	3	of	of	IN
cord-264532-xfb94lq8	70	4	model	model	NN
cord-264532-xfb94lq8	70	5	can	can	MD
cord-264532-xfb94lq8	70	6	be	be	VB
cord-264532-xfb94lq8	70	7	used	use	VBN
cord-264532-xfb94lq8	70	8	to	to	TO
cord-264532-xfb94lq8	70	9	make	make	VB
cord-264532-xfb94lq8	70	10	the	the	DT
cord-264532-xfb94lq8	70	11	same	same	JJ
cord-264532-xfb94lq8	70	12	point	point	NN
cord-264532-xfb94lq8	70	13	,	,	,
cord-264532-xfb94lq8	70	14	however	however	RB
cord-264532-xfb94lq8	70	15	.	.	.
cord-264532-xfb94lq8	71	1	Invasion	invasion	NN
cord-264532-xfb94lq8	71	2	criteria	criterion	NNS
cord-264532-xfb94lq8	71	3	are	be	VBP
cord-264532-xfb94lq8	71	4	permissive	permissive	JJ
cord-264532-xfb94lq8	72	1	An	an	DT
cord-264532-xfb94lq8	72	2	optimum	optimum	NN
cord-264532-xfb94lq8	72	3	is	be	VBZ
cord-264532-xfb94lq8	72	4	best	well	RBS
cord-264532-xfb94lq8	72	5	regarded	regard	VBN
cord-264532-xfb94lq8	72	6	as	as	IN
cord-264532-xfb94lq8	72	7	a	a	DT
cord-264532-xfb94lq8	72	8	long	long	JJ
cord-264532-xfb94lq8	72	9	-	-	HYPH
cord-264532-xfb94lq8	72	10	term	term	NN
cord-264532-xfb94lq8	72	11	endpoint	endpoint	NN
cord-264532-xfb94lq8	72	12	of	of	IN
cord-264532-xfb94lq8	72	13	evolution	evolution	NN
cord-264532-xfb94lq8	72	14	.	.	.
cord-264532-xfb94lq8	73	1	Prior	prior	RB
cord-264532-xfb94lq8	73	2	to	to	IN
cord-264532-xfb94lq8	73	3	attaining	attain	VBG
cord-264532-xfb94lq8	73	4	an	an	DT
cord-264532-xfb94lq8	73	5	optimum	optimum	JJ
cord-264532-xfb94lq8	73	6	,	,	,
cord-264532-xfb94lq8	73	7	however	however	RB
cord-264532-xfb94lq8	73	8	,	,	,
cord-264532-xfb94lq8	73	9	the	the	DT
cord-264532-xfb94lq8	73	10	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	73	11	dynamics	dynamic	NNS
cord-264532-xfb94lq8	73	12	apply	apply	VBP
cord-264532-xfb94lq8	73	13	(	(	-LRB-
cord-264532-xfb94lq8	73	14	as	as	IN
cord-264532-xfb94lq8	73	15	codified	codify	VBN
cord-264532-xfb94lq8	73	16	by	by	IN
cord-264532-xfb94lq8	73	17	Day	Day	NNP
cord-264532-xfb94lq8	73	18	and	and	CC
cord-264532-xfb94lq8	73	19	Gandon	Gandon	NNP
cord-264532-xfb94lq8	73	20	2006	2006	CD
cord-264532-xfb94lq8	73	21	,	,	,
cord-264532-xfb94lq8	73	22	for	for	IN
cord-264532-xfb94lq8	73	23	example	example	NN
cord-264532-xfb94lq8	73	24	)	)	-RRB-
cord-264532-xfb94lq8	73	25	.	.	.
cord-264532-xfb94lq8	74	1	Even	even	RB
cord-264532-xfb94lq8	74	2	before	before	IN
cord-264532-xfb94lq8	74	3	dynamics	dynamic	NNS
cord-264532-xfb94lq8	74	4	are	be	VBP
cord-264532-xfb94lq8	74	5	relevant	relevant	JJ
cord-264532-xfb94lq8	74	6	,	,	,
cord-264532-xfb94lq8	74	7	the	the	DT
cord-264532-xfb94lq8	74	8	issue	issue	NN
cord-264532-xfb94lq8	74	9	is	be	VBZ
cord-264532-xfb94lq8	74	10	merely	merely	RB
cord-264532-xfb94lq8	74	11	what	what	WDT
cord-264532-xfb94lq8	74	12	range	range	NN
cord-264532-xfb94lq8	74	13	of	of	IN
cord-264532-xfb94lq8	74	14	parasite	parasite	NN
cord-264532-xfb94lq8	74	15	phenotypes	phenotype	NNS
cord-264532-xfb94lq8	74	16	/	/	SYM
cord-264532-xfb94lq8	74	17	genotypes	genotype	NNS
cord-264532-xfb94lq8	74	18	can	can	MD
cord-264532-xfb94lq8	74	19	invade	invade	VB
cord-264532-xfb94lq8	74	20	the	the	DT
cord-264532-xfb94lq8	74	21	host	host	NN
cord-264532-xfb94lq8	74	22	population	population	NN
cord-264532-xfb94lq8	74	23	.	.	.
cord-264532-xfb94lq8	75	1	The	the	DT
cord-264532-xfb94lq8	75	2	invasion	invasion	NN
cord-264532-xfb94lq8	75	3	threshold	threshold	NN
cord-264532-xfb94lq8	75	4	provides	provide	VBZ
cord-264532-xfb94lq8	75	5	the	the	DT
cord-264532-xfb94lq8	75	6	boundary	boundary	NN
cord-264532-xfb94lq8	75	7	to	to	IN
cord-264532-xfb94lq8	75	8	the	the	DT
cord-264532-xfb94lq8	75	9	range	range	NN
cord-264532-xfb94lq8	75	10	of	of	IN
cord-264532-xfb94lq8	75	11	parameters	parameter	NNS
cord-264532-xfb94lq8	75	12	that	that	WDT
cord-264532-xfb94lq8	75	13	allows	allow	VBZ
cord-264532-xfb94lq8	75	14	invasion	invasion	NN
cord-264532-xfb94lq8	75	15	.	.	.
cord-264532-xfb94lq8	76	1	It	-PRON-	PRP
cord-264532-xfb94lq8	76	2	is	be	VBZ
cord-264532-xfb94lq8	76	3	the	the	DT
cord-264532-xfb94lq8	76	4	set	set	NN
cord-264532-xfb94lq8	76	5	of	of	IN
cord-264532-xfb94lq8	76	6	all	all	DT
cord-264532-xfb94lq8	76	7	(	(	-LRB-
cord-264532-xfb94lq8	76	8	mutant	mutant	JJ
cord-264532-xfb94lq8	76	9	)	)	-RRB-
cord-264532-xfb94lq8	76	10	parameter	parameter	NN
cord-264532-xfb94lq8	76	11	combinations	combination	NNS
cord-264532-xfb94lq8	76	12	for	for	IN
cord-264532-xfb94lq8	76	13	which	which	WDT
cord-264532-xfb94lq8	76	14	the	the	DT
cord-264532-xfb94lq8	76	15	parasite	parasite	NN
cord-264532-xfb94lq8	76	16	neither	neither	CC
cord-264532-xfb94lq8	76	17	invades	invade	VBZ
cord-264532-xfb94lq8	76	18	nor	nor	CC
cord-264532-xfb94lq8	76	19	goes	go	VBZ
cord-264532-xfb94lq8	76	20	extinct	extinct	JJ
cord-264532-xfb94lq8	76	21	.	.	.
cord-264532-xfb94lq8	77	1	Thus	thus	RB
cord-264532-xfb94lq8	77	2	,	,	,
cord-264532-xfb94lq8	77	3	parameter	parameter	NN
cord-264532-xfb94lq8	77	4	values	value	NNS
cord-264532-xfb94lq8	77	5	on	on	IN
cord-264532-xfb94lq8	77	6	one	one	CD
cord-264532-xfb94lq8	77	7	side	side	NN
cord-264532-xfb94lq8	77	8	of	of	IN
cord-264532-xfb94lq8	77	9	the	the	DT
cord-264532-xfb94lq8	77	10	invasion	invasion	NN
cord-264532-xfb94lq8	77	11	threshold	threshold	NN
cord-264532-xfb94lq8	77	12	will	will	MD
cord-264532-xfb94lq8	77	13	allow	allow	VB
cord-264532-xfb94lq8	77	14	invasion	invasion	NN
cord-264532-xfb94lq8	77	15	,	,	,
cord-264532-xfb94lq8	77	16	whereas	whereas	IN
cord-264532-xfb94lq8	77	17	those	those	DT
cord-264532-xfb94lq8	77	18	on	on	IN
cord-264532-xfb94lq8	77	19	the	the	DT
cord-264532-xfb94lq8	77	20	other	other	JJ
cord-264532-xfb94lq8	77	21	side	side	NN
cord-264532-xfb94lq8	77	22	will	will	MD
cord-264532-xfb94lq8	77	23	lead	lead	VB
cord-264532-xfb94lq8	77	24	to	to	IN
cord-264532-xfb94lq8	77	25	loss	loss	NN
cord-264532-xfb94lq8	77	26	/	/	SYM
cord-264532-xfb94lq8	77	27	extinction	extinction	NN
cord-264532-xfb94lq8	77	28	.	.	.
cord-264532-xfb94lq8	77	29	.	.	.
cord-264532-xfb94lq8	78	1	Death	death	NN
cord-264532-xfb94lq8	78	2	rate	rate	NN
cord-264532-xfb94lq8	78	3	is	be	VBZ
cord-264532-xfb94lq8	78	4	divided	divide	VBN
cord-264532-xfb94lq8	78	5	into	into	IN
cord-264532-xfb94lq8	78	6	intrinsic	intrinsic	JJ
cord-264532-xfb94lq8	78	7	host	host	NN
cord-264532-xfb94lq8	78	8	death	death	NN
cord-264532-xfb94lq8	78	9	rate	rate	NN
cord-264532-xfb94lq8	78	10	and	and	CC
cord-264532-xfb94lq8	78	11	virulence	virulence	NN
cord-264532-xfb94lq8	78	12	-parasite	-parasite	NN
cord-264532-xfb94lq8	78	13	-	-	HYPH
cord-264532-xfb94lq8	78	14	induced	induce	VBN
cord-264532-xfb94lq8	78	15	host	host	NN
cord-264532-xfb94lq8	78	16	death	death	NN
cord-264532-xfb94lq8	78	17	rate	rate	NN
cord-264532-xfb94lq8	78	18	.	.	.
cord-264532-xfb94lq8	79	1	The	the	DT
cord-264532-xfb94lq8	79	2	intrinsic	intrinsic	JJ
cord-264532-xfb94lq8	79	3	host	host	NN
cord-264532-xfb94lq8	79	4	death	death	NN
cord-264532-xfb94lq8	79	5	rate	rate	NN
cord-264532-xfb94lq8	79	6	is	be	VBZ
cord-264532-xfb94lq8	79	7	assumed	assume	VBN
cord-264532-xfb94lq8	79	8	to	to	TO
cord-264532-xfb94lq8	79	9	be	be	VB
cord-264532-xfb94lq8	79	10	constant	constant	JJ
cord-264532-xfb94lq8	79	11	,	,	,
cord-264532-xfb94lq8	79	12	so	so	IN
cord-264532-xfb94lq8	79	13	the	the	DT
cord-264532-xfb94lq8	79	14	virulence	virulence	NN
cord-264532-xfb94lq8	79	15	-	-	HYPH
cord-264532-xfb94lq8	79	16	transmission	transmission	NN
cord-264532-xfb94lq8	79	17	trade	trade	NN
cord-264532-xfb94lq8	79	18	-	-	HYPH
cord-264532-xfb94lq8	79	19	off	off	NN
cord-264532-xfb94lq8	79	20	(	(	-LRB-
cord-264532-xfb94lq8	79	21	dashed	dash	VBN
cord-264532-xfb94lq8	79	22	curve	curve	NN
cord-264532-xfb94lq8	79	23	)	)	-RRB-
cord-264532-xfb94lq8	79	24	emanates	emanate	VBZ
cord-264532-xfb94lq8	79	25	from	from	IN
cord-264532-xfb94lq8	79	26	the	the	DT
cord-264532-xfb94lq8	79	27	axis	axis	NN
cord-264532-xfb94lq8	79	28	at	at	IN
cord-264532-xfb94lq8	79	29	this	this	DT
cord-264532-xfb94lq8	79	30	value	value	NN
cord-264532-xfb94lq8	79	31	and	and	CC
cord-264532-xfb94lq8	79	32	increases	increase	NNS
cord-264532-xfb94lq8	79	33	as	as	IN
cord-264532-xfb94lq8	79	34	transmission	transmission	NN
cord-264532-xfb94lq8	79	35	increases	increase	NNS
cord-264532-xfb94lq8	79	36	.	.	.
cord-264532-xfb94lq8	80	1	The	the	DT
cord-264532-xfb94lq8	80	2	trade	trade	NN
cord-264532-xfb94lq8	80	3	-	-	HYPH
cord-264532-xfb94lq8	80	4	off	off	NN
cord-264532-xfb94lq8	80	5	gives	give	VBZ
cord-264532-xfb94lq8	80	6	the	the	DT
cord-264532-xfb94lq8	80	7	minimum	minimum	JJ
cord-264532-xfb94lq8	80	8	total	total	JJ
cord-264532-xfb94lq8	80	9	parasite	parasite	JJ
cord-264532-xfb94lq8	80	10	death	death	NN
cord-264532-xfb94lq8	80	11	rate	rate	NN
cord-264532-xfb94lq8	80	12	(	(	-LRB-
cord-264532-xfb94lq8	80	13	d	d	NN
cord-264532-xfb94lq8	80	14	)	)	-RRB-
cord-264532-xfb94lq8	80	15	that	that	WDT
cord-264532-xfb94lq8	80	16	could	could	MD
cord-264532-xfb94lq8	80	17	be	be	VB
cord-264532-xfb94lq8	80	18	achieved	achieve	VBN
cord-264532-xfb94lq8	80	19	for	for	IN
cord-264532-xfb94lq8	80	20	a	a	DT
cord-264532-xfb94lq8	80	21	given	give	VBN
cord-264532-xfb94lq8	80	22	transmission	transmission	NN
cord-264532-xfb94lq8	80	23	rate	rate	NN
cord-264532-xfb94lq8	80	24	(	(	-LRB-
cord-264532-xfb94lq8	80	25	b	b	NN
cord-264532-xfb94lq8	80	26	)	)	-RRB-
cord-264532-xfb94lq8	80	27	,	,	,
cord-264532-xfb94lq8	80	28	so	so	RB
cord-264532-xfb94lq8	80	29	only	only	JJ
cord-264532-xfb94lq8	80	30	points	point	NNS
cord-264532-xfb94lq8	80	31	on	on	RB
cord-264532-xfb94lq8	80	32	and	and	CC
cord-264532-xfb94lq8	80	33	above	above	IN
cord-264532-xfb94lq8	80	34	the	the	DT
cord-264532-xfb94lq8	80	35	trade	trade	NN
cord-264532-xfb94lq8	80	36	-	-	HYPH
cord-264532-xfb94lq8	80	37	off	off	RP
cord-264532-xfb94lq8	80	38	boundary	boundary	NN
cord-264532-xfb94lq8	80	39	are	be	VBP
cord-264532-xfb94lq8	80	40	attainable	attainable	JJ
cord-264532-xfb94lq8	80	41	by	by	IN
cord-264532-xfb94lq8	80	42	the	the	DT
cord-264532-xfb94lq8	80	43	parasite	parasite	NN
cord-264532-xfb94lq8	80	44	(	(	-LRB-
cord-264532-xfb94lq8	80	45	shaded	shade	VBN
cord-264532-xfb94lq8	80	46	)	)	-RRB-
cord-264532-xfb94lq8	80	47	.	.	.
cord-264532-xfb94lq8	81	1	For	for	IN
cord-264532-xfb94lq8	81	2	simplicity	simplicity	NN
cord-264532-xfb94lq8	81	3	,	,	,
cord-264532-xfb94lq8	81	4	we	-PRON-	PRP
cord-264532-xfb94lq8	81	5	henceforth	henceforth	RB
cord-264532-xfb94lq8	81	6	refer	refer	VBP
cord-264532-xfb94lq8	81	7	to	to	IN
cord-264532-xfb94lq8	81	8	d	d	NN
cord-264532-xfb94lq8	81	9	as	as	IN
cord-264532-xfb94lq8	81	10	virulence	virulence	NN
cord-264532-xfb94lq8	81	11	,	,	,
cord-264532-xfb94lq8	81	12	but	but	CC
cord-264532-xfb94lq8	81	13	acknowledge	acknowledge	VB
cord-264532-xfb94lq8	81	14	that	that	IN
cord-264532-xfb94lq8	81	15	it	-PRON-	PRP
cord-264532-xfb94lq8	81	16	is	be	VBZ
cord-264532-xfb94lq8	81	17	the	the	DT
cord-264532-xfb94lq8	81	18	sum	sum	NN
cord-264532-xfb94lq8	81	19	of	of	IN
cord-264532-xfb94lq8	81	20	a	a	DT
cord-264532-xfb94lq8	81	21	constant	constant	JJ
cord-264532-xfb94lq8	81	22	mortality	mortality	NN
cord-264532-xfb94lq8	81	23	plus	plus	IN
cord-264532-xfb94lq8	81	24	virulence	virulence	NN
cord-264532-xfb94lq8	81	25	.	.	.
cord-264532-xfb94lq8	82	1	(	(	-LRB-
cord-264532-xfb94lq8	82	2	Bottom	bottom	NN
cord-264532-xfb94lq8	82	3	)	)	-RRB-
cord-264532-xfb94lq8	82	4	Optimum	optimum	NN
cord-264532-xfb94lq8	82	5	for	for	IN
cord-264532-xfb94lq8	82	6	a	a	DT
cord-264532-xfb94lq8	82	7	parasite	parasite	NN
cord-264532-xfb94lq8	82	8	invading	invade	VBG
cord-264532-xfb94lq8	82	9	a	a	DT
cord-264532-xfb94lq8	82	10	host	host	NN
cord-264532-xfb94lq8	82	11	population	population	NN
cord-264532-xfb94lq8	82	12	,	,	,
cord-264532-xfb94lq8	82	13	when	when	WRB
cord-264532-xfb94lq8	82	14	the	the	DT
cord-264532-xfb94lq8	82	15	susceptible	susceptible	JJ
cord-264532-xfb94lq8	82	16	host	host	NN
cord-264532-xfb94lq8	82	17	density	density	NN
cord-264532-xfb94lq8	82	18	remains	remain	VBZ
cord-264532-xfb94lq8	82	19	constant	constant	JJ
cord-264532-xfb94lq8	82	20	at	at	IN
cord-264532-xfb94lq8	82	21	S.	S.	NNP
cord-264532-xfb94lq8	83	1	During	during	IN
cord-264532-xfb94lq8	83	2	the	the	DT
cord-264532-xfb94lq8	83	3	epidemic	epidemic	NN
cord-264532-xfb94lq8	83	4	phase	phase	NN
cord-264532-xfb94lq8	83	5	,	,	,
cord-264532-xfb94lq8	83	6	the	the	DT
cord-264532-xfb94lq8	83	7	parasite	parasite	NN
cord-264532-xfb94lq8	83	8	's	's	POS
cord-264532-xfb94lq8	83	9	optimum	optimum	JJ
cord-264532-xfb94lq8	83	10	lies	lie	NNS
cord-264532-xfb94lq8	83	11	on	on	IN
cord-264532-xfb94lq8	83	12	the	the	DT
cord-264532-xfb94lq8	83	13	dashed	dash	VBN
cord-264532-xfb94lq8	83	14	tradeoff	tradeoff	NN
cord-264532-xfb94lq8	83	15	function	function	NN
cord-264532-xfb94lq8	83	16	and	and	CC
cord-264532-xfb94lq8	83	17	satisfies	satisfy	VBZ
cord-264532-xfb94lq8	83	18	the	the	DT
cord-264532-xfb94lq8	83	19	condition	condition	NN
cord-264532-xfb94lq8	83	20	that	that	IN
cord-264532-xfb94lq8	83	21	the	the	DT
cord-264532-xfb94lq8	83	22	slope	slope	NN
cord-264532-xfb94lq8	83	23	of	of	IN
cord-264532-xfb94lq8	83	24	the	the	DT
cord-264532-xfb94lq8	83	25	tangent	tangent	NN
cord-264532-xfb94lq8	83	26	along	along	IN
cord-264532-xfb94lq8	83	27	the	the	DT
cord-264532-xfb94lq8	83	28	trade	trade	NN
cord-264532-xfb94lq8	83	29	-	-	HYPH
cord-264532-xfb94lq8	83	30	off	off	RP
cord-264532-xfb94lq8	83	31	function	function	NN
cord-264532-xfb94lq8	83	32	equals	equal	VBZ
cord-264532-xfb94lq8	83	33	the	the	DT
cord-264532-xfb94lq8	83	34	current	current	JJ
cord-264532-xfb94lq8	83	35	density	density	NN
cord-264532-xfb94lq8	83	36	of	of	IN
cord-264532-xfb94lq8	83	37	hosts	host	NNS
cord-264532-xfb94lq8	83	38	,	,	,
cord-264532-xfb94lq8	83	39	S	S	NNP
cord-264532-xfb94lq8	83	40	(	(	-LRB-
cord-264532-xfb94lq8	83	41	upper	upper	JJ
cord-264532-xfb94lq8	83	42	arrow	arrow	NN
cord-264532-xfb94lq8	83	43	)	)	-RRB-
cord-264532-xfb94lq8	83	44	.	.	.
cord-264532-xfb94lq8	84	1	As	as	IN
cord-264532-xfb94lq8	84	2	the	the	DT
cord-264532-xfb94lq8	84	3	parasite	parasite	NN
cord-264532-xfb94lq8	84	4	epidemic	epidemic	NN
cord-264532-xfb94lq8	84	5	reduces	reduce	VBZ
cord-264532-xfb94lq8	84	6	the	the	DT
cord-264532-xfb94lq8	84	7	density	density	NN
cord-264532-xfb94lq8	84	8	of	of	IN
cord-264532-xfb94lq8	84	9	susceptible	susceptible	JJ
cord-264532-xfb94lq8	84	10	hosts	host	NNS
cord-264532-xfb94lq8	84	11	,	,	,
cord-264532-xfb94lq8	84	12	the	the	DT
cord-264532-xfb94lq8	84	13	optimum	optimum	JJ
cord-264532-xfb94lq8	84	14	shifts	shift	NNS
cord-264532-xfb94lq8	84	15	progressively	progressively	RB
cord-264532-xfb94lq8	84	16	further	further	RB
cord-264532-xfb94lq8	84	17	down	down	IN
cord-264532-xfb94lq8	84	18	the	the	DT
cord-264532-xfb94lq8	84	19	tradeoff	tradeoff	NN
cord-264532-xfb94lq8	84	20	curve	curve	NN
cord-264532-xfb94lq8	84	21	,	,	,
cord-264532-xfb94lq8	84	22	until	until	IN
cord-264532-xfb94lq8	84	23	dynamic	dynamic	JJ
cord-264532-xfb94lq8	84	24	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	84	25	is	be	VBZ
cord-264532-xfb94lq8	84	26	reached	reach	VBN
cord-264532-xfb94lq8	84	27	,	,	,
cord-264532-xfb94lq8	84	28	whereby	whereby	WRB
cord-264532-xfb94lq8	84	29	parasite	parasite	NN
cord-264532-xfb94lq8	84	30	and	and	CC
cord-264532-xfb94lq8	84	31	host	host	NN
cord-264532-xfb94lq8	84	32	densities	density	NNS
cord-264532-xfb94lq8	84	33	remain	remain	VBP
cord-264532-xfb94lq8	84	34	constant	constant	JJ
cord-264532-xfb94lq8	84	35	.	.	.
cord-264532-xfb94lq8	85	1	In	in	IN
cord-264532-xfb94lq8	85	2	this	this	DT
cord-264532-xfb94lq8	85	3	state	state	NN
cord-264532-xfb94lq8	85	4	,	,	,
cord-264532-xfb94lq8	85	5	the	the	DT
cord-264532-xfb94lq8	85	6	parasite	parasite	NN
cord-264532-xfb94lq8	85	7	optimum	optimum	NN
cord-264532-xfb94lq8	85	8	maximizes	maximize	VBZ
cord-264532-xfb94lq8	85	9	R	r	NN
cord-264532-xfb94lq8	85	10	0	0	CD
cord-264532-xfb94lq8	85	11	=	=	SYM
cord-264532-xfb94lq8	85	12	b	b	NN
cord-264532-xfb94lq8	85	13	/	/	SYM
cord-264532-xfb94lq8	85	14	d	d	NN
cord-264532-xfb94lq8	85	15	,	,	,
cord-264532-xfb94lq8	85	16	given	give	VBN
cord-264532-xfb94lq8	85	17	by	by	IN
cord-264532-xfb94lq8	85	18	the	the	DT
cord-264532-xfb94lq8	85	19	point	point	NN
cord-264532-xfb94lq8	85	20	at	at	IN
cord-264532-xfb94lq8	85	21	which	which	WDT
cord-264532-xfb94lq8	85	22	a	a	DT
cord-264532-xfb94lq8	85	23	line	line	NN
cord-264532-xfb94lq8	85	24	through	through	IN
cord-264532-xfb94lq8	85	25	the	the	DT
cord-264532-xfb94lq8	85	26	origin	origin	NN
cord-264532-xfb94lq8	85	27	is	be	VBZ
cord-264532-xfb94lq8	85	28	tangent	tangent	JJ
cord-264532-xfb94lq8	85	29	to	to	IN
cord-264532-xfb94lq8	85	30	the	the	DT
cord-264532-xfb94lq8	85	31	trade	trade	NN
cord-264532-xfb94lq8	85	32	-	-	HYPH
cord-264532-xfb94lq8	85	33	off	off	RP
cord-264532-xfb94lq8	85	34	function	function	NN
cord-264532-xfb94lq8	85	35	(	(	-LRB-
cord-264532-xfb94lq8	85	36	lower	low	JJR
cord-264532-xfb94lq8	85	37	arrow	arrow	NN
cord-264532-xfb94lq8	85	38	)	)	-RRB-
cord-264532-xfb94lq8	85	39	.	.	.
cord-264532-xfb94lq8	86	1	In	in	IN
cord-264532-xfb94lq8	86	2	this	this	DT
cord-264532-xfb94lq8	86	3	paper	paper	NN
cord-264532-xfb94lq8	86	4	,	,	,
cord-264532-xfb94lq8	86	5	we	-PRON-	PRP
cord-264532-xfb94lq8	86	6	are	be	VBP
cord-264532-xfb94lq8	86	7	concerned	concerned	JJ
cord-264532-xfb94lq8	86	8	chiefly	chiefly	RB
cord-264532-xfb94lq8	86	9	with	with	IN
cord-264532-xfb94lq8	86	10	conditions	condition	NNS
cord-264532-xfb94lq8	86	11	at	at	IN
cord-264532-xfb94lq8	86	12	and	and	CC
cord-264532-xfb94lq8	86	13	shortly	shortly	RB
cord-264532-xfb94lq8	86	14	after	after	IN
cord-264532-xfb94lq8	86	15	the	the	DT
cord-264532-xfb94lq8	86	16	time	time	NN
cord-264532-xfb94lq8	86	17	of	of	IN
cord-264532-xfb94lq8	86	18	invasion	invasion	NN
cord-264532-xfb94lq8	86	19	,	,	,
cord-264532-xfb94lq8	86	20	before	before	IN
cord-264532-xfb94lq8	86	21	the	the	DT
cord-264532-xfb94lq8	86	22	population	population	NN
cord-264532-xfb94lq8	86	23	has	have	VBZ
cord-264532-xfb94lq8	86	24	reached	reach	VBN
cord-264532-xfb94lq8	86	25	dynamic	dynamic	JJ
cord-264532-xfb94lq8	86	26	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	86	27	.	.	.
cord-264532-xfb94lq8	87	1	The	the	DT
cord-264532-xfb94lq8	87	2	invasion	invasion	NN
cord-264532-xfb94lq8	87	3	threshold	threshold	NN
cord-264532-xfb94lq8	87	4	is	be	VBZ
cord-264532-xfb94lq8	87	5	easily	easily	RB
cord-264532-xfb94lq8	87	6	found	find	VBN
cord-264532-xfb94lq8	87	7	in	in	IN
cord-264532-xfb94lq8	87	8	our	-PRON-	PRP$
cord-264532-xfb94lq8	87	9	model	model	NN
cord-264532-xfb94lq8	87	10	.	.	.
cord-264532-xfb94lq8	88	1	Extending	extend	VBG
cord-264532-xfb94lq8	88	2	result	result	NN
cord-264532-xfb94lq8	88	3	(	(	-LRB-
cord-264532-xfb94lq8	88	4	1b	1b	LS
cord-264532-xfb94lq8	88	5	)	)	-RRB-
cord-264532-xfb94lq8	88	6	above	above	RB
cord-264532-xfb94lq8	88	7	,	,	,
cord-264532-xfb94lq8	88	8	the	the	DT
cord-264532-xfb94lq8	88	9	pathogen	pathogen	NN
cord-264532-xfb94lq8	88	10	invades	invade	VBZ
cord-264532-xfb94lq8	88	11	if	if	IN
cord-264532-xfb94lq8	88	12	dI/	dI/	NNP
cord-264532-xfb94lq8	88	13	dt	dt	XX
cord-264532-xfb94lq8	88	14	>	>	XX
cord-264532-xfb94lq8	88	15	0	0	CD
cord-264532-xfb94lq8	88	16	,	,	,
cord-264532-xfb94lq8	88	17	or	or	CC
cord-264532-xfb94lq8	88	18	The	the	DT
cord-264532-xfb94lq8	88	19	invasion	invasion	NN
cord-264532-xfb94lq8	88	20	threshold	threshold	NN
cord-264532-xfb94lq8	88	21	is	be	VBZ
cord-264532-xfb94lq8	88	22	thus	thus	RB
cord-264532-xfb94lq8	88	23	found	find	VBN
cord-264532-xfb94lq8	88	24	by	by	IN
cord-264532-xfb94lq8	88	25	replacing	replace	VBG
cord-264532-xfb94lq8	88	26	the	the	DT
cord-264532-xfb94lq8	88	27	inequality	inequality	NN
cord-264532-xfb94lq8	88	28	in	in	IN
cord-264532-xfb94lq8	88	29	equation	equation	NN
cord-264532-xfb94lq8	88	30	(	(	-LRB-
cord-264532-xfb94lq8	88	31	3	3	LS
cord-264532-xfb94lq8	88	32	)	)	-RRB-
cord-264532-xfb94lq8	88	33	with	with	IN
cord-264532-xfb94lq8	88	34	equality	equality	NN
cord-264532-xfb94lq8	88	35	.	.	.
cord-264532-xfb94lq8	89	1	The	the	DT
cord-264532-xfb94lq8	89	2	set	set	NN
cord-264532-xfb94lq8	89	3	of	of	IN
cord-264532-xfb94lq8	89	4	parameters	parameter	NNS
cord-264532-xfb94lq8	89	5	for	for	IN
cord-264532-xfb94lq8	89	6	invasion	invasion	NN
cord-264532-xfb94lq8	89	7	of	of	IN
cord-264532-xfb94lq8	89	8	a	a	DT
cord-264532-xfb94lq8	89	9	host	host	NN
cord-264532-xfb94lq8	89	10	population	population	NN
cord-264532-xfb94lq8	89	11	whose	whose	WP$
cord-264532-xfb94lq8	89	12	density	density	NN
cord-264532-xfb94lq8	89	13	is	be	VBZ
cord-264532-xfb94lq8	89	14	S	s	NN
cord-264532-xfb94lq8	89	15	*	*	NFP
cord-264532-xfb94lq8	89	16	can	can	MD
cord-264532-xfb94lq8	89	17	be	be	VB
cord-264532-xfb94lq8	89	18	represented	represent	VBN
cord-264532-xfb94lq8	89	19	in	in	IN
cord-264532-xfb94lq8	89	20	a	a	DT
cord-264532-xfb94lq8	89	21	two	two	CD
cord-264532-xfb94lq8	89	22	-	-	HYPH
cord-264532-xfb94lq8	89	23	dimensional	dimensional	JJ
cord-264532-xfb94lq8	89	24	coordinate	coordinate	NN
cord-264532-xfb94lq8	89	25	system	system	NN
cord-264532-xfb94lq8	89	26	as	as	IN
cord-264532-xfb94lq8	89	27	the	the	DT
cord-264532-xfb94lq8	89	28	points	point	NNS
cord-264532-xfb94lq8	89	29	falling	fall	VBG
cord-264532-xfb94lq8	89	30	below	below	IN
cord-264532-xfb94lq8	89	31	a	a	DT
cord-264532-xfb94lq8	89	32	line	line	NN
cord-264532-xfb94lq8	89	33	of	of	IN
cord-264532-xfb94lq8	89	34	slope	slope	NN
cord-264532-xfb94lq8	89	35	S	s	NN
cord-264532-xfb94lq8	89	36	*	*	NFP
cord-264532-xfb94lq8	89	37	passing	pass	VBG
cord-264532-xfb94lq8	89	38	through	through	IN
cord-264532-xfb94lq8	89	39	the	the	DT
cord-264532-xfb94lq8	89	40	origin	origin	NN
cord-264532-xfb94lq8	89	41	(	(	-LRB-
cord-264532-xfb94lq8	89	42	Fig	Fig	NNP
cord-264532-xfb94lq8	89	43	.	.	NNP
cord-264532-xfb94lq8	89	44	2	2	CD
cord-264532-xfb94lq8	89	45	,	,	,
cord-264532-xfb94lq8	89	46	top	top	NN
cord-264532-xfb94lq8	89	47	)	)	-RRB-
cord-264532-xfb94lq8	89	48	and	and	CC
cord-264532-xfb94lq8	89	49	above	above	IN
cord-264532-xfb94lq8	89	50	the	the	DT
cord-264532-xfb94lq8	89	51	trade	trade	NN
cord-264532-xfb94lq8	89	52	-	-	HYPH
cord-264532-xfb94lq8	89	53	off	off	RP
cord-264532-xfb94lq8	89	54	boundary	boundary	NN
cord-264532-xfb94lq8	89	55	.	.	.
cord-264532-xfb94lq8	90	1	This	this	DT
cord-264532-xfb94lq8	90	2	graph	graph	NN
cord-264532-xfb94lq8	90	3	illustrates	illustrate	VBZ
cord-264532-xfb94lq8	90	4	why	why	WRB
cord-264532-xfb94lq8	90	5	the	the	DT
cord-264532-xfb94lq8	90	6	transmission	transmission	NN
cord-264532-xfb94lq8	90	7	and	and	CC
cord-264532-xfb94lq8	90	8	virulence	virulence	NN
cord-264532-xfb94lq8	90	9	state	state	NN
cord-264532-xfb94lq8	90	10	(	(	-LRB-
cord-264532-xfb94lq8	90	11	b	b	NN
cord-264532-xfb94lq8	90	12	,	,	,
cord-264532-xfb94lq8	90	13	d	d	LS
cord-264532-xfb94lq8	90	14	)	)	-RRB-
cord-264532-xfb94lq8	90	15	that	that	WDT
cord-264532-xfb94lq8	90	16	maximizes	maximize	VBZ
cord-264532-xfb94lq8	90	17	fitness	fitness	NN
cord-264532-xfb94lq8	90	18	gives	give	VBZ
cord-264532-xfb94lq8	90	19	an	an	DT
cord-264532-xfb94lq8	90	20	inadequate	inadequate	JJ
cord-264532-xfb94lq8	90	21	picture	picture	NN
cord-264532-xfb94lq8	90	22	of	of	IN
cord-264532-xfb94lq8	90	23	the	the	DT
cord-264532-xfb94lq8	90	24	levels	level	NNS
cord-264532-xfb94lq8	90	25	of	of	IN
cord-264532-xfb94lq8	90	26	virulence	virulence	NN
cord-264532-xfb94lq8	90	27	that	that	WDT
cord-264532-xfb94lq8	90	28	can	can	MD
cord-264532-xfb94lq8	90	29	invade	invade	VB
cord-264532-xfb94lq8	90	30	the	the	DT
cord-264532-xfb94lq8	90	31	population	population	NN
cord-264532-xfb94lq8	90	32	.	.	.
cord-264532-xfb94lq8	91	1	Any	any	DT
cord-264532-xfb94lq8	91	2	point	point	NN
cord-264532-xfb94lq8	91	3	inside	inside	IN
cord-264532-xfb94lq8	91	4	the	the	DT
cord-264532-xfb94lq8	91	5	region	region	NN
cord-264532-xfb94lq8	91	6	between	between	IN
cord-264532-xfb94lq8	91	7	the	the	DT
cord-264532-xfb94lq8	91	8	invasion	invasion	NN
cord-264532-xfb94lq8	91	9	boundary	boundary	JJ
cord-264532-xfb94lq8	91	10	line	line	NN
cord-264532-xfb94lq8	91	11	and	and	CC
cord-264532-xfb94lq8	91	12	the	the	DT
cord-264532-xfb94lq8	91	13	trade	trade	NN
cord-264532-xfb94lq8	91	14	-	-	HYPH
cord-264532-xfb94lq8	91	15	off	off	RP
cord-264532-xfb94lq8	91	16	boundary	boundary	NN
cord-264532-xfb94lq8	91	17	represents	represent	VBZ
cord-264532-xfb94lq8	91	18	a	a	DT
cord-264532-xfb94lq8	91	19	pair	pair	NN
cord-264532-xfb94lq8	91	20	of	of	IN
cord-264532-xfb94lq8	91	21	parasite	parasite	NN
cord-264532-xfb94lq8	91	22	values	value	NNS
cord-264532-xfb94lq8	91	23	(	(	-LRB-
cord-264532-xfb94lq8	91	24	b	b	NN
cord-264532-xfb94lq8	91	25	,	,	,
cord-264532-xfb94lq8	91	26	d	d	LS
cord-264532-xfb94lq8	91	27	)	)	-RRB-
cord-264532-xfb94lq8	91	28	that	that	WDT
cord-264532-xfb94lq8	91	29	can	can	MD
cord-264532-xfb94lq8	91	30	invade	invade	VB
cord-264532-xfb94lq8	91	31	.	.	.
cord-264532-xfb94lq8	92	1	Thus	thus	RB
cord-264532-xfb94lq8	92	2	,	,	,
cord-264532-xfb94lq8	92	3	the	the	DT
cord-264532-xfb94lq8	92	4	population	population	NN
cord-264532-xfb94lq8	92	5	is	be	VBZ
cord-264532-xfb94lq8	92	6	susceptible	susceptible	JJ
cord-264532-xfb94lq8	92	7	to	to	IN
cord-264532-xfb94lq8	92	8	invasion	invasion	NN
cord-264532-xfb94lq8	92	9	by	by	IN
cord-264532-xfb94lq8	92	10	far	far	RB
cord-264532-xfb94lq8	92	11	more	more	RBR
cord-264532-xfb94lq8	92	12	virulent	virulent	JJ
cord-264532-xfb94lq8	92	13	parasites	parasite	NNS
cord-264532-xfb94lq8	92	14	and	and	CC
cord-264532-xfb94lq8	92	15	by	by	IN
cord-264532-xfb94lq8	92	16	far	far	RB
cord-264532-xfb94lq8	92	17	less	less	RBR
cord-264532-xfb94lq8	92	18	virulent	virulent	JJ
cord-264532-xfb94lq8	92	19	parasites	parasite	NNS
cord-264532-xfb94lq8	92	20	than	than	IN
cord-264532-xfb94lq8	92	21	those	those	DT
cord-264532-xfb94lq8	92	22	at	at	IN
cord-264532-xfb94lq8	92	23	the	the	DT
cord-264532-xfb94lq8	92	24	optimum	optimum	NN
cord-264532-xfb94lq8	92	25	,	,	,
cord-264532-xfb94lq8	92	26	a	a	DT
cord-264532-xfb94lq8	92	27	point	point	NN
cord-264532-xfb94lq8	92	28	made	make	VBN
cord-264532-xfb94lq8	92	29	by	by	IN
cord-264532-xfb94lq8	92	30	Andre	Andre	NNP
cord-264532-xfb94lq8	92	31	and	and	CC
cord-264532-xfb94lq8	92	32	Hochberg	Hochberg	NNP
cord-264532-xfb94lq8	92	33	(	(	-LRB-
cord-264532-xfb94lq8	92	34	2005	2005	CD
cord-264532-xfb94lq8	92	35	)	)	-RRB-
cord-264532-xfb94lq8	92	36	.	.	.
cord-264532-xfb94lq8	93	1	Although	although	IN
cord-264532-xfb94lq8	93	2	all	all	DT
cord-264532-xfb94lq8	93	3	values	value	NNS
cord-264532-xfb94lq8	93	4	below	below	IN
cord-264532-xfb94lq8	93	5	the	the	DT
cord-264532-xfb94lq8	93	6	line	line	NN
cord-264532-xfb94lq8	93	7	can	can	MD
cord-264532-xfb94lq8	93	8	invade	invade	VB
cord-264532-xfb94lq8	93	9	,	,	,
cord-264532-xfb94lq8	93	10	not	not	RB
cord-264532-xfb94lq8	93	11	all	all	DT
cord-264532-xfb94lq8	93	12	have	have	VBP
cord-264532-xfb94lq8	93	13	the	the	DT
cord-264532-xfb94lq8	93	14	same	same	JJ
cord-264532-xfb94lq8	93	15	fitness	fitness	NN
cord-264532-xfb94lq8	93	16	,	,	,
cord-264532-xfb94lq8	93	17	so	so	RB
cord-264532-xfb94lq8	93	18	further	further	JJ
cord-264532-xfb94lq8	93	19	evolution	evolution	NN
cord-264532-xfb94lq8	93	20	is	be	VBZ
cord-264532-xfb94lq8	93	21	expected	expect	VBN
cord-264532-xfb94lq8	93	22	whenever	whenever	WRB
cord-264532-xfb94lq8	93	23	the	the	DT
cord-264532-xfb94lq8	93	24	invading	invade	VBG
cord-264532-xfb94lq8	93	25	genotype	genotype	NN
cord-264532-xfb94lq8	93	26	is	be	VBZ
cord-264532-xfb94lq8	93	27	not	not	RB
cord-264532-xfb94lq8	93	28	at	at	IN
cord-264532-xfb94lq8	93	29	the	the	DT
cord-264532-xfb94lq8	93	30	optimum	optimum	NN
cord-264532-xfb94lq8	93	31	.	.	.
cord-264532-xfb94lq8	94	1	Evolution	evolution	NN
cord-264532-xfb94lq8	94	2	following	follow	VBG
cord-264532-xfb94lq8	94	3	invasion	invasion	NN
cord-264532-xfb94lq8	94	4	may	may	MD
cord-264532-xfb94lq8	94	5	be	be	VB
cord-264532-xfb94lq8	94	6	slow	slow	JJ
cord-264532-xfb94lq8	94	7	to	to	TO
cord-264532-xfb94lq8	94	8	attain	attain	VB
cord-264532-xfb94lq8	94	9	the	the	DT
cord-264532-xfb94lq8	94	10	optimum	optimum	JJ
cord-264532-xfb94lq8	94	11	Following	Following	NNP
cord-264532-xfb94lq8	94	12	Day	Day	NNP
cord-264532-xfb94lq8	94	13	and	and	CC
cord-264532-xfb94lq8	94	14	Proulx	Proulx	NNP
cord-264532-xfb94lq8	94	15	(	(	-LRB-
cord-264532-xfb94lq8	94	16	2004	2004	CD
cord-264532-xfb94lq8	94	17	)	)	-RRB-
cord-264532-xfb94lq8	94	18	,	,	,
cord-264532-xfb94lq8	94	19	if	if	IN
cord-264532-xfb94lq8	94	20	the	the	DT
cord-264532-xfb94lq8	94	21	invading	invade	VBG
cord-264532-xfb94lq8	94	22	parasite	parasite	NN
cord-264532-xfb94lq8	94	23	persists	persist	VBZ
cord-264532-xfb94lq8	94	24	and	and	CC
cord-264532-xfb94lq8	94	25	becomes	become	VBZ
cord-264532-xfb94lq8	94	26	established	establish	VBN
cord-264532-xfb94lq8	94	27	,	,	,
cord-264532-xfb94lq8	94	28	it	-PRON-	PRP
cord-264532-xfb94lq8	94	29	is	be	VBZ
cord-264532-xfb94lq8	94	30	expected	expect	VBN
cord-264532-xfb94lq8	94	31	that	that	IN
cord-264532-xfb94lq8	94	32	virulence	virulence	NN
cord-264532-xfb94lq8	94	33	and	and	CC
cord-264532-xfb94lq8	94	34	transmission	transmission	NN
cord-264532-xfb94lq8	94	35	will	will	MD
cord-264532-xfb94lq8	94	36	begin	begin	VB
cord-264532-xfb94lq8	94	37	to	to	TO
cord-264532-xfb94lq8	94	38	evolve	evolve	VB
cord-264532-xfb94lq8	94	39	toward	toward	IN
cord-264532-xfb94lq8	94	40	values	value	NNS
cord-264532-xfb94lq8	94	41	that	that	WDT
cord-264532-xfb94lq8	94	42	improve	improve	VBP
cord-264532-xfb94lq8	94	43	parasite	parasite	NN
cord-264532-xfb94lq8	94	44	fitness	fitness	NN
cord-264532-xfb94lq8	94	45	.	.	.
cord-264532-xfb94lq8	95	1	Indeed	indeed	RB
cord-264532-xfb94lq8	95	2	,	,	,
cord-264532-xfb94lq8	95	3	if	if	IN
cord-264532-xfb94lq8	95	4	evolution	evolution	NN
cord-264532-xfb94lq8	95	5	to	to	IN
cord-264532-xfb94lq8	95	6	the	the	DT
cord-264532-xfb94lq8	95	7	optimum	optimum	NN
cord-264532-xfb94lq8	95	8	is	be	VBZ
cord-264532-xfb94lq8	95	9	fast	fast	JJ
cord-264532-xfb94lq8	95	10	enough	enough	RB
cord-264532-xfb94lq8	95	11	,	,	,
cord-264532-xfb94lq8	95	12	the	the	DT
cord-264532-xfb94lq8	95	13	duration	duration	NN
cord-264532-xfb94lq8	95	14	of	of	IN
cord-264532-xfb94lq8	95	15	nonoptimal	nonoptimal	JJ
cord-264532-xfb94lq8	95	16	parasite	parasite	NN
cord-264532-xfb94lq8	95	17	behavior	behavior	NN
cord-264532-xfb94lq8	95	18	could	could	MD
cord-264532-xfb94lq8	95	19	be	be	VB
cord-264532-xfb94lq8	95	20	ignored	ignore	VBN
cord-264532-xfb94lq8	95	21	.	.	.
cord-264532-xfb94lq8	96	1	Yet	yet	RB
cord-264532-xfb94lq8	96	2	,	,	,
cord-264532-xfb94lq8	96	3	the	the	DT
cord-264532-xfb94lq8	96	4	approach	approach	NN
cord-264532-xfb94lq8	96	5	to	to	TO
cord-264532-xfb94lq8	96	6	optimum	optimum	JJ
cord-264532-xfb94lq8	96	7	virulence	virulence	NN
cord-264532-xfb94lq8	96	8	may	may	MD
cord-264532-xfb94lq8	96	9	be	be	VB
cord-264532-xfb94lq8	96	10	slow	slow	JJ
cord-264532-xfb94lq8	96	11	for	for	IN
cord-264532-xfb94lq8	96	12	a	a	DT
cord-264532-xfb94lq8	96	13	few	few	JJ
cord-264532-xfb94lq8	96	14	reasons	reason	NNS
cord-264532-xfb94lq8	96	15	:	:	:
cord-264532-xfb94lq8	97	1	(	(	-LRB-
cord-264532-xfb94lq8	97	2	i	i	NN
cord-264532-xfb94lq8	97	3	)	)	-RRB-
cord-264532-xfb94lq8	97	4	the	the	DT
cord-264532-xfb94lq8	97	5	optimum	optimum	NN
cord-264532-xfb94lq8	97	6	may	may	MD
cord-264532-xfb94lq8	97	7	be	be	VB
cord-264532-xfb94lq8	97	8	changing	change	VBG
cord-264532-xfb94lq8	97	9	(	(	-LRB-
cord-264532-xfb94lq8	97	10	Lenski	Lenski	NNP
cord-264532-xfb94lq8	97	11	and	and	CC
cord-264532-xfb94lq8	97	12	May	May	NNP
cord-264532-xfb94lq8	97	13	1994	1994	CD
cord-264532-xfb94lq8	97	14	)	)	-RRB-
cord-264532-xfb94lq8	97	15	,	,	.
cord-264532-xfb94lq8	98	1	(	(	-LRB-
cord-264532-xfb94lq8	98	2	ii	ii	LS
cord-264532-xfb94lq8	98	3	)	)	-RRB-
cord-264532-xfb94lq8	98	4	virulence	virulence	NN
cord-264532-xfb94lq8	98	5	evolution	evolution	NN
cord-264532-xfb94lq8	98	6	will	will	MD
cord-264532-xfb94lq8	98	7	be	be	VB
cord-264532-xfb94lq8	98	8	influenced	influence	VBN
cord-264532-xfb94lq8	98	9	by	by	IN
cord-264532-xfb94lq8	98	10	the	the	DT
cord-264532-xfb94lq8	98	11	genetic	genetic	JJ
cord-264532-xfb94lq8	98	12	covariance	covariance	NN
cord-264532-xfb94lq8	98	13	or	or	CC
cord-264532-xfb94lq8	98	14	mutational	mutational	JJ
cord-264532-xfb94lq8	98	15	properties	property	NNS
cord-264532-xfb94lq8	98	16	between	between	IN
cord-264532-xfb94lq8	98	17	virulence	virulence	NN
cord-264532-xfb94lq8	98	18	and	and	CC
cord-264532-xfb94lq8	98	19	transmission	transmission	NN
cord-264532-xfb94lq8	98	20	(	(	-LRB-
cord-264532-xfb94lq8	98	21	Day	Day	NNP
cord-264532-xfb94lq8	98	22	and	and	CC
cord-264532-xfb94lq8	98	23	Gandon	Gandon	NNP
cord-264532-xfb94lq8	98	24	2006	2006	CD
cord-264532-xfb94lq8	98	25	)	)	-RRB-
cord-264532-xfb94lq8	98	26	,	,	,
cord-264532-xfb94lq8	98	27	and	and	CC
cord-264532-xfb94lq8	98	28	Conditions	condition	NNS
cord-264532-xfb94lq8	98	29	for	for	IN
cord-264532-xfb94lq8	98	30	the	the	DT
cord-264532-xfb94lq8	98	31	invasion	invasion	NN
cord-264532-xfb94lq8	98	32	of	of	IN
cord-264532-xfb94lq8	98	33	a	a	DT
cord-264532-xfb94lq8	98	34	host	host	NN
cord-264532-xfb94lq8	98	35	population	population	NN
cord-264532-xfb94lq8	98	36	of	of	IN
cord-264532-xfb94lq8	98	37	density	density	NN
cord-264532-xfb94lq8	98	38	S	S	NNP
cord-264532-xfb94lq8	98	39	*	*	NFP
cord-264532-xfb94lq8	98	40	by	by	IN
cord-264532-xfb94lq8	98	41	a	a	DT
cord-264532-xfb94lq8	98	42	parasite	parasite	NN
cord-264532-xfb94lq8	98	43	with	with	IN
cord-264532-xfb94lq8	98	44	parameters	parameter	NNS
cord-264532-xfb94lq8	98	45	(	(	-LRB-
cord-264532-xfb94lq8	98	46	d	d	NN
cord-264532-xfb94lq8	98	47	,	,	,
cord-264532-xfb94lq8	98	48	b	b	LS
cord-264532-xfb94lq8	98	49	)	)	-RRB-
cord-264532-xfb94lq8	98	50	are	be	VBP
cord-264532-xfb94lq8	98	51	S	s	NN
cord-264532-xfb94lq8	98	52	*	*	NFP
cord-264532-xfb94lq8	98	53	>	>	XX
cord-264532-xfb94lq8	99	1	d	d	NNP
cord-264532-xfb94lq8	99	2	/	/	SYM
cord-264532-xfb94lq8	99	3	b	b	NNP
cord-264532-xfb94lq8	99	4	,	,	,
cord-264532-xfb94lq8	99	5	where	where	WRB
cord-264532-xfb94lq8	99	6	d	d	NNP
cord-264532-xfb94lq8	99	7	is	be	VBZ
cord-264532-xfb94lq8	99	8	virulence	virulence	NN
cord-264532-xfb94lq8	99	9	and	and	CC
cord-264532-xfb94lq8	99	10	b	b	NN
cord-264532-xfb94lq8	99	11	is	be	VBZ
cord-264532-xfb94lq8	99	12	the	the	DT
cord-264532-xfb94lq8	99	13	transmission	transmission	NN
cord-264532-xfb94lq8	99	14	rate	rate	NN
cord-264532-xfb94lq8	99	15	.	.	.
cord-264532-xfb94lq8	100	1	Points	point	NNS
cord-264532-xfb94lq8	100	2	satisfying	satisfy	VBG
cord-264532-xfb94lq8	100	3	S	s	NN
cord-264532-xfb94lq8	101	1	*	*	NFP
cord-264532-xfb94lq8	101	2	=	=	SYM
cord-264532-xfb94lq8	101	3	d	d	NN
cord-264532-xfb94lq8	101	4	/	/	SYM
cord-264532-xfb94lq8	101	5	b	b	NN
cord-264532-xfb94lq8	101	6	lie	lie	VB
cord-264532-xfb94lq8	101	7	a	a	DT
cord-264532-xfb94lq8	101	8	line	line	NN
cord-264532-xfb94lq8	101	9	radiating	radiate	VBG
cord-264532-xfb94lq8	101	10	from	from	IN
cord-264532-xfb94lq8	101	11	the	the	DT
cord-264532-xfb94lq8	101	12	origin	origin	NN
cord-264532-xfb94lq8	101	13	(	(	-LRB-
cord-264532-xfb94lq8	101	14	of	of	IN
cord-264532-xfb94lq8	101	15	slope	slope	NN
cord-264532-xfb94lq8	101	16	S	S	NNP
cord-264532-xfb94lq8	101	17	*	*	NFP
cord-264532-xfb94lq8	101	18	)	)	-RRB-
cord-264532-xfb94lq8	101	19	,	,	,
cord-264532-xfb94lq8	101	20	so	so	RB
cord-264532-xfb94lq8	101	21	radii	radii	JJ
cord-264532-xfb94lq8	101	22	with	with	IN
cord-264532-xfb94lq8	101	23	progressively	progressively	RB
cord-264532-xfb94lq8	101	24	higher	high	JJR
cord-264532-xfb94lq8	101	25	slopes	slope	NNS
cord-264532-xfb94lq8	101	26	represent	represent	VBP
cord-264532-xfb94lq8	101	27	parasite	parasite	NN
cord-264532-xfb94lq8	101	28	parameters	parameter	NNS
cord-264532-xfb94lq8	101	29	that	that	WDT
cord-264532-xfb94lq8	101	30	can	can	MD
cord-264532-xfb94lq8	101	31	invade	invade	VB
cord-264532-xfb94lq8	101	32	only	only	RB
cord-264532-xfb94lq8	101	33	at	at	IN
cord-264532-xfb94lq8	101	34	progressively	progressively	RB
cord-264532-xfb94lq8	101	35	higher	high	JJR
cord-264532-xfb94lq8	101	36	host	host	NN
cord-264532-xfb94lq8	101	37	densities	density	NNS
cord-264532-xfb94lq8	101	38	.	.	.
cord-264532-xfb94lq8	102	1	All	all	DT
cord-264532-xfb94lq8	102	2	parasites	parasite	NNS
cord-264532-xfb94lq8	102	3	whose	whose	WP$
cord-264532-xfb94lq8	102	4	values	value	NNS
cord-264532-xfb94lq8	102	5	fall	fall	VBP
cord-264532-xfb94lq8	102	6	in	in	IN
cord-264532-xfb94lq8	102	7	the	the	DT
cord-264532-xfb94lq8	102	8	darker	darker	RBR
cord-264532-xfb94lq8	102	9	shaded	shaded	JJ
cord-264532-xfb94lq8	102	10	region	region	NN
cord-264532-xfb94lq8	102	11	below	below	IN
cord-264532-xfb94lq8	102	12	the	the	DT
cord-264532-xfb94lq8	102	13	line	line	NN
cord-264532-xfb94lq8	102	14	of	of	IN
cord-264532-xfb94lq8	102	15	slope	slope	NN
cord-264532-xfb94lq8	102	16	S	s	NN
cord-264532-xfb94lq8	102	17	*	*	NFP
cord-264532-xfb94lq8	103	1	and	and	CC
cord-264532-xfb94lq8	103	2	above	above	IN
cord-264532-xfb94lq8	103	3	the	the	DT
cord-264532-xfb94lq8	103	4	dashed	dash	VBN
cord-264532-xfb94lq8	103	5	trade	trade	NN
cord-264532-xfb94lq8	103	6	-	-	HYPH
cord-264532-xfb94lq8	103	7	off	off	RP
cord-264532-xfb94lq8	103	8	boundary	boundary	NN
cord-264532-xfb94lq8	103	9	are	be	VBP
cord-264532-xfb94lq8	103	10	attainable	attainable	JJ
cord-264532-xfb94lq8	103	11	and	and	CC
cord-264532-xfb94lq8	103	12	can	can	MD
cord-264532-xfb94lq8	103	13	invade	invade	VB
cord-264532-xfb94lq8	103	14	,	,	,
cord-264532-xfb94lq8	103	15	whereas	whereas	IN
cord-264532-xfb94lq8	103	16	the	the	DT
cord-264532-xfb94lq8	103	17	lightshaded	lightshaded	JJ
cord-264532-xfb94lq8	103	18	region	region	NN
cord-264532-xfb94lq8	103	19	above	above	IN
cord-264532-xfb94lq8	103	20	the	the	DT
cord-264532-xfb94lq8	103	21	invasion	invasion	NN
cord-264532-xfb94lq8	103	22	boundary	boundary	NN
cord-264532-xfb94lq8	103	23	represents	represent	VBZ
cord-264532-xfb94lq8	103	24	values	value	NNS
cord-264532-xfb94lq8	103	25	that	that	IN
cord-264532-xfb94lq8	103	26	the	the	DT
cord-264532-xfb94lq8	103	27	parasite	parasite	NN
cord-264532-xfb94lq8	103	28	can	can	MD
cord-264532-xfb94lq8	103	29	attain	attain	VB
cord-264532-xfb94lq8	103	30	but	but	CC
cord-264532-xfb94lq8	103	31	do	do	VBP
cord-264532-xfb94lq8	103	32	not	not	RB
cord-264532-xfb94lq8	103	33	allow	allow	VB
cord-264532-xfb94lq8	103	34	invasion	invasion	NN
cord-264532-xfb94lq8	103	35	(	(	-LRB-
cord-264532-xfb94lq8	103	36	for	for	IN
cord-264532-xfb94lq8	103	37	host	host	NN
cord-264532-xfb94lq8	103	38	density	density	NN
cord-264532-xfb94lq8	103	39	S	S	NNP
cord-264532-xfb94lq8	103	40	*	*	NFP
cord-264532-xfb94lq8	103	41	)	)	-RRB-
cord-264532-xfb94lq8	103	42	.	.	.
cord-264532-xfb94lq8	104	1	The	the	DT
cord-264532-xfb94lq8	104	2	parasite	parasite	NN
cord-264532-xfb94lq8	104	3	population	population	NN
cord-264532-xfb94lq8	104	4	would	would	MD
cord-264532-xfb94lq8	104	5	eventually	eventually	RB
cord-264532-xfb94lq8	104	6	evolve	evolve	VB
cord-264532-xfb94lq8	104	7	toward	toward	IN
cord-264532-xfb94lq8	104	8	the	the	DT
cord-264532-xfb94lq8	104	9	dot	dot	NN
cord-264532-xfb94lq8	104	10	on	on	IN
cord-264532-xfb94lq8	104	11	the	the	DT
cord-264532-xfb94lq8	104	12	trade	trade	NN
cord-264532-xfb94lq8	104	13	-	-	HYPH
cord-264532-xfb94lq8	104	14	off	off	RP
cord-264532-xfb94lq8	104	15	boundary	boundary	NN
cord-264532-xfb94lq8	104	16	(	(	-LRB-
cord-264532-xfb94lq8	104	17	arrows	arrow	NNS
cord-264532-xfb94lq8	104	18	)	)	-RRB-
cord-264532-xfb94lq8	104	19	,	,	,
cord-264532-xfb94lq8	104	20	but	but	CC
cord-264532-xfb94lq8	104	21	it	-PRON-	PRP
cord-264532-xfb94lq8	104	22	could	could	MD
cord-264532-xfb94lq8	104	23	create	create	VB
cord-264532-xfb94lq8	104	24	a	a	DT
cord-264532-xfb94lq8	104	25	potentially	potentially	RB
cord-264532-xfb94lq8	104	26	highly	highly	RB
cord-264532-xfb94lq8	104	27	virulent	virulent	JJ
cord-264532-xfb94lq8	104	28	epidemic	epidemic	NN
cord-264532-xfb94lq8	104	29	from	from	IN
cord-264532-xfb94lq8	104	30	the	the	DT
cord-264532-xfb94lq8	104	31	start	start	NN
cord-264532-xfb94lq8	104	32	of	of	IN
cord-264532-xfb94lq8	104	33	the	the	DT
cord-264532-xfb94lq8	104	34	invasion	invasion	NN
cord-264532-xfb94lq8	104	35	until	until	IN
cord-264532-xfb94lq8	104	36	the	the	DT
cord-264532-xfb94lq8	104	37	evolutionarily	evolutionarily	RB
cord-264532-xfb94lq8	104	38	equilibrium	equilibrium	JJ
cord-264532-xfb94lq8	104	39	virulence	virulence	NN
cord-264532-xfb94lq8	104	40	was	be	VBD
cord-264532-xfb94lq8	104	41	attained	attain	VBN
cord-264532-xfb94lq8	104	42	.	.	.
cord-264532-xfb94lq8	105	1	(	(	-LRB-
cord-264532-xfb94lq8	105	2	Bottom	bottom	NN
cord-264532-xfb94lq8	105	3	)	)	-RRB-
cord-264532-xfb94lq8	106	1	Evolution	evolution	NN
cord-264532-xfb94lq8	106	2	following	follow	VBG
cord-264532-xfb94lq8	106	3	invasion	invasion	NN
cord-264532-xfb94lq8	106	4	may	may	MD
cord-264532-xfb94lq8	106	5	be	be	VB
cord-264532-xfb94lq8	106	6	slow	slow	JJ
cord-264532-xfb94lq8	106	7	to	to	TO
cord-264532-xfb94lq8	106	8	approach	approach	VB
cord-264532-xfb94lq8	106	9	optimal	optimal	JJ
cord-264532-xfb94lq8	106	10	virulence	virulence	NN
cord-264532-xfb94lq8	106	11	.	.	.
cord-264532-xfb94lq8	107	1	The	the	DT
cord-264532-xfb94lq8	107	2	rightmost	rightmost	JJ
cord-264532-xfb94lq8	107	3	oblique	oblique	JJ
cord-264532-xfb94lq8	107	4	line	line	NN
cord-264532-xfb94lq8	107	5	is	be	VBZ
cord-264532-xfb94lq8	107	6	a	a	DT
cord-264532-xfb94lq8	107	7	fitness	fitness	NN
cord-264532-xfb94lq8	107	8	isocline	isocline	NN
cord-264532-xfb94lq8	107	9	(	(	-LRB-
cord-264532-xfb94lq8	107	10	of	of	IN
cord-264532-xfb94lq8	107	11	slope	slope	NN
cord-264532-xfb94lq8	107	12	S	S	NNP
cord-264532-xfb94lq8	107	13	*	*	NFP
cord-264532-xfb94lq8	107	14	)	)	-RRB-
cord-264532-xfb94lq8	107	15	,	,	,
cord-264532-xfb94lq8	107	16	and	and	CC
cord-264532-xfb94lq8	107	17	all	all	DT
cord-264532-xfb94lq8	107	18	points	point	NNS
cord-264532-xfb94lq8	107	19	on	on	IN
cord-264532-xfb94lq8	107	20	it	-PRON-	PRP
cord-264532-xfb94lq8	107	21	have	have	VBP
cord-264532-xfb94lq8	107	22	equal	equal	JJ
cord-264532-xfb94lq8	107	23	fitness	fitness	NN
cord-264532-xfb94lq8	107	24	,	,	,
cord-264532-xfb94lq8	107	25	superior	superior	JJ
cord-264532-xfb94lq8	107	26	to	to	IN
cord-264532-xfb94lq8	107	27	the	the	DT
cord-264532-xfb94lq8	107	28	fitnesses	fitness	NNS
cord-264532-xfb94lq8	107	29	of	of	IN
cord-264532-xfb94lq8	107	30	all	all	DT
cord-264532-xfb94lq8	107	31	points	point	NNS
cord-264532-xfb94lq8	107	32	to	to	IN
cord-264532-xfb94lq8	107	33	its	-PRON-	PRP$
cord-264532-xfb94lq8	107	34	left	left	NN
cord-264532-xfb94lq8	107	35	.	.	.
cord-264532-xfb94lq8	108	1	Evolution	evolution	NN
cord-264532-xfb94lq8	108	2	would	would	MD
cord-264532-xfb94lq8	108	3	tend	tend	VB
cord-264532-xfb94lq8	108	4	to	to	TO
cord-264532-xfb94lq8	108	5	move	move	VB
cord-264532-xfb94lq8	108	6	parasites	parasite	NNS
cord-264532-xfb94lq8	108	7	progressively	progressively	RB
cord-264532-xfb94lq8	108	8	toward	toward	IN
cord-264532-xfb94lq8	108	9	right	right	RB
cord-264532-xfb94lq8	108	10	-	-	HYPH
cord-264532-xfb94lq8	108	11	most	most	JJS
cord-264532-xfb94lq8	108	12	isoclines	isocline	NNS
cord-264532-xfb94lq8	108	13	,	,	,
cord-264532-xfb94lq8	108	14	but	but	CC
cord-264532-xfb94lq8	108	15	as	as	IN
cord-264532-xfb94lq8	108	16	a	a	DT
cord-264532-xfb94lq8	108	17	mutant	mutant	NN
cord-264532-xfb94lq8	108	18	's	's	POS
cord-264532-xfb94lq8	108	19	relative	relative	JJ
cord-264532-xfb94lq8	108	20	position	position	NN
cord-264532-xfb94lq8	108	21	on	on	IN
cord-264532-xfb94lq8	108	22	the	the	DT
cord-264532-xfb94lq8	108	23	fitness	fitness	NN
cord-264532-xfb94lq8	108	24	isocline	isocline	NN
cord-264532-xfb94lq8	108	25	does	do	VBZ
cord-264532-xfb94lq8	108	26	not	not	RB
cord-264532-xfb94lq8	108	27	affect	affect	VB
cord-264532-xfb94lq8	108	28	its	-PRON-	PRP$
cord-264532-xfb94lq8	108	29	fitness	fitness	NN
cord-264532-xfb94lq8	108	30	,	,	,
cord-264532-xfb94lq8	108	31	evolution	evolution	NN
cord-264532-xfb94lq8	108	32	at	at	IN
cord-264532-xfb94lq8	108	33	each	each	DT
cord-264532-xfb94lq8	108	34	step	step	NN
cord-264532-xfb94lq8	108	35	could	could	MD
cord-264532-xfb94lq8	108	36	move	move	VB
cord-264532-xfb94lq8	108	37	virulence	virulence	NN
cord-264532-xfb94lq8	108	38	further	far	RBR
cord-264532-xfb94lq8	108	39	or	or	CC
cord-264532-xfb94lq8	108	40	closer	close	RBR
cord-264532-xfb94lq8	108	41	to	to	IN
cord-264532-xfb94lq8	108	42	the	the	DT
cord-264532-xfb94lq8	108	43	optimum	optimum	JJ
cord-264532-xfb94lq8	108	44	(	(	-LRB-
cord-264532-xfb94lq8	108	45	solid	solid	JJ
cord-264532-xfb94lq8	108	46	point	point	NN
cord-264532-xfb94lq8	108	47	)	)	-RRB-
cord-264532-xfb94lq8	108	48	until	until	IN
cord-264532-xfb94lq8	108	49	the	the	DT
cord-264532-xfb94lq8	108	50	optimum	optimum	NN
cord-264532-xfb94lq8	108	51	was	be	VBD
cord-264532-xfb94lq8	108	52	approached	approach	VBN
cord-264532-xfb94lq8	108	53	closely	closely	RB
cord-264532-xfb94lq8	108	54	.	.	.
cord-264532-xfb94lq8	109	1	The	the	DT
cord-264532-xfb94lq8	109	2	input	input	NN
cord-264532-xfb94lq8	109	3	of	of	IN
cord-264532-xfb94lq8	109	4	mutations	mutation	NNS
cord-264532-xfb94lq8	109	5	(	(	-LRB-
cord-264532-xfb94lq8	109	6	or	or	CC
cord-264532-xfb94lq8	109	7	genetic	genetic	JJ
cord-264532-xfb94lq8	109	8	covariance	covariance	NN
cord-264532-xfb94lq8	109	9	between	between	IN
cord-264532-xfb94lq8	109	10	transmission	transmission	NN
cord-264532-xfb94lq8	109	11	and	and	CC
cord-264532-xfb94lq8	109	12	virulence	virulence	NN
cord-264532-xfb94lq8	109	13	)	)	-RRB-
cord-264532-xfb94lq8	109	14	thus	thus	RB
cord-264532-xfb94lq8	109	15	has	have	VBZ
cord-264532-xfb94lq8	109	16	a	a	DT
cord-264532-xfb94lq8	109	17	major	major	JJ
cord-264532-xfb94lq8	109	18	impact	impact	NN
cord-264532-xfb94lq8	109	19	on	on	IN
cord-264532-xfb94lq8	109	20	the	the	DT
cord-264532-xfb94lq8	109	21	evolution	evolution	NN
cord-264532-xfb94lq8	109	22	of	of	IN
cord-264532-xfb94lq8	109	23	virulence	virulence	NN
cord-264532-xfb94lq8	109	24	in	in	IN
cord-264532-xfb94lq8	109	25	these	these	DT
cord-264532-xfb94lq8	109	26	early	early	JJ
cord-264532-xfb94lq8	109	27	stages	stage	NNS
cord-264532-xfb94lq8	109	28	(	(	-LRB-
cord-264532-xfb94lq8	109	29	Day	Day	NNP
cord-264532-xfb94lq8	109	30	and	and	CC
cord-264532-xfb94lq8	109	31	Gandon	Gandon	NNP
cord-264532-xfb94lq8	109	32	2007	2007	CD
cord-264532-xfb94lq8	109	33	)	)	-RRB-
cord-264532-xfb94lq8	109	34	.	.	.
cord-264532-xfb94lq8	110	1	Improved	improved	JJ
cord-264532-xfb94lq8	110	2	fitness	fitness	NN
cord-264532-xfb94lq8	110	3	need	need	VBP
cord-264532-xfb94lq8	110	4	not	not	RB
cord-264532-xfb94lq8	110	5	greatly	greatly	RB
cord-264532-xfb94lq8	110	6	restrict	restrict	VB
cord-264532-xfb94lq8	110	7	the	the	DT
cord-264532-xfb94lq8	110	8	range	range	NN
cord-264532-xfb94lq8	110	9	of	of	IN
cord-264532-xfb94lq8	110	10	virulence	virulence	NN
cord-264532-xfb94lq8	110	11	values	value	NNS
cord-264532-xfb94lq8	110	12	allowed	allow	VBN
cord-264532-xfb94lq8	110	13	,	,	,
cord-264532-xfb94lq8	110	14	and	and	CC
cord-264532-xfb94lq8	110	15	indeed	indeed	RB
cord-264532-xfb94lq8	110	16	,	,	,
cord-264532-xfb94lq8	110	17	virulence	virulence	NN
cord-264532-xfb94lq8	110	18	could	could	MD
cord-264532-xfb94lq8	110	19	evolve	evolve	VB
cord-264532-xfb94lq8	110	20	to	to	TO
cord-264532-xfb94lq8	110	21	deviate	deviate	VB
cord-264532-xfb94lq8	110	22	further	further	RB
cord-264532-xfb94lq8	110	23	from	from	IN
cord-264532-xfb94lq8	110	24	its	-PRON-	PRP$
cord-264532-xfb94lq8	110	25	optimum	optimum	NN
cord-264532-xfb94lq8	110	26	during	during	IN
cord-264532-xfb94lq8	110	27	intermediate	intermediate	JJ
cord-264532-xfb94lq8	110	28	stages	stage	NNS
cord-264532-xfb94lq8	110	29	of	of	IN
cord-264532-xfb94lq8	110	30	the	the	DT
cord-264532-xfb94lq8	110	31	adaptation	adaptation	NN
cord-264532-xfb94lq8	110	32	.	.	.
cord-264532-xfb94lq8	111	1	These	these	DT
cord-264532-xfb94lq8	111	2	arguments	argument	NNS
cord-264532-xfb94lq8	111	3	apply	apply	VBP
cord-264532-xfb94lq8	111	4	to	to	IN
cord-264532-xfb94lq8	111	5	constant	constant	JJ
cord-264532-xfb94lq8	111	6	host	host	NN
cord-264532-xfb94lq8	111	7	density	density	NN
cord-264532-xfb94lq8	111	8	,	,	,
cord-264532-xfb94lq8	111	9	and	and	CC
cord-264532-xfb94lq8	111	10	if	if	IN
cord-264532-xfb94lq8	111	11	susceptible	susceptible	JJ
cord-264532-xfb94lq8	111	12	host	host	NN
cord-264532-xfb94lq8	111	13	density	density	NN
cord-264532-xfb94lq8	111	14	is	be	VBZ
cord-264532-xfb94lq8	111	15	declining	decline	VBG
cord-264532-xfb94lq8	111	16	,	,	,
cord-264532-xfb94lq8	111	17	the	the	DT
cord-264532-xfb94lq8	111	18	fitness	fitness	NN
cord-264532-xfb94lq8	111	19	isoclines	isocline	NNS
cord-264532-xfb94lq8	111	20	will	will	MD
cord-264532-xfb94lq8	111	21	have	have	VB
cord-264532-xfb94lq8	111	22	progressively	progressively	RB
cord-264532-xfb94lq8	111	23	shallower	shallow	JJR
cord-264532-xfb94lq8	111	24	slopes	slope	NNS
cord-264532-xfb94lq8	111	25	.	.	.
cord-264532-xfb94lq8	112	1	(	(	-LRB-
cord-264532-xfb94lq8	112	2	iii	iii	LS
cord-264532-xfb94lq8	112	3	)	)	-RRB-
cord-264532-xfb94lq8	112	4	there	there	EX
cord-264532-xfb94lq8	112	5	may	may	MD
cord-264532-xfb94lq8	112	6	simply	simply	RB
cord-264532-xfb94lq8	112	7	be	be	VB
cord-264532-xfb94lq8	112	8	little	little	JJ
cord-264532-xfb94lq8	112	9	genetic	genetic	JJ
cord-264532-xfb94lq8	112	10	variation	variation	NN
cord-264532-xfb94lq8	112	11	(	(	-LRB-
cord-264532-xfb94lq8	112	12	see	see	VB
cord-264532-xfb94lq8	112	13	also	also	RB
cord-264532-xfb94lq8	112	14	Day	Day	NNP
cord-264532-xfb94lq8	112	15	and	and	CC
cord-264532-xfb94lq8	112	16	Proulx	Proulx	NNP
cord-264532-xfb94lq8	112	17	2004	2004	CD
cord-264532-xfb94lq8	112	18	)	)	-RRB-
cord-264532-xfb94lq8	112	19	.	.	.
cord-264532-xfb94lq8	113	1	As	as	IN
cord-264532-xfb94lq8	113	2	Lenski	Lenski	NNP
cord-264532-xfb94lq8	113	3	and	and	CC
cord-264532-xfb94lq8	113	4	May	May	NNP
cord-264532-xfb94lq8	113	5	(	(	-LRB-
cord-264532-xfb94lq8	113	6	1994	1994	CD
cord-264532-xfb94lq8	113	7	)	)	-RRB-
cord-264532-xfb94lq8	113	8	pointed	point	VBD
cord-264532-xfb94lq8	113	9	out	out	RP
cord-264532-xfb94lq8	113	10	,	,	,
cord-264532-xfb94lq8	113	11	(	(	-LRB-
cord-264532-xfb94lq8	113	12	i	i	NN
cord-264532-xfb94lq8	113	13	)	)	-RRB-
cord-264532-xfb94lq8	113	14	the	the	DT
cord-264532-xfb94lq8	113	15	optimum	optimum	NN
cord-264532-xfb94lq8	113	16	will	will	MD
cord-264532-xfb94lq8	113	17	shift	shift	VB
cord-264532-xfb94lq8	113	18	toward	toward	IN
cord-264532-xfb94lq8	113	19	progressively	progressively	RB
cord-264532-xfb94lq8	113	20	lower	low	JJR
cord-264532-xfb94lq8	113	21	virulence	virulence	NN
cord-264532-xfb94lq8	113	22	values	value	NNS
cord-264532-xfb94lq8	113	23	as	as	IN
cord-264532-xfb94lq8	113	24	the	the	DT
cord-264532-xfb94lq8	113	25	density	density	NN
cord-264532-xfb94lq8	113	26	of	of	IN
cord-264532-xfb94lq8	113	27	the	the	DT
cord-264532-xfb94lq8	113	28	susceptible	susceptible	JJ
cord-264532-xfb94lq8	113	29	hosts	host	NNS
cord-264532-xfb94lq8	113	30	is	be	VBZ
cord-264532-xfb94lq8	113	31	reduced	reduce	VBN
cord-264532-xfb94lq8	113	32	by	by	IN
cord-264532-xfb94lq8	113	33	the	the	DT
cord-264532-xfb94lq8	113	34	epidemic	epidemic	NN
cord-264532-xfb94lq8	113	35	.	.	.
cord-264532-xfb94lq8	114	1	Thus	thus	RB
cord-264532-xfb94lq8	114	2	the	the	DT
cord-264532-xfb94lq8	114	3	optimum	optimum	NN
cord-264532-xfb94lq8	114	4	will	will	MD
cord-264532-xfb94lq8	114	5	not	not	RB
cord-264532-xfb94lq8	114	6	be	be	VB
cord-264532-xfb94lq8	114	7	static	static	JJ
cord-264532-xfb94lq8	114	8	,	,	,
cord-264532-xfb94lq8	114	9	and	and	CC
cord-264532-xfb94lq8	114	10	the	the	DT
cord-264532-xfb94lq8	114	11	parasite	parasite	NN
cord-264532-xfb94lq8	114	12	can	can	MD
cord-264532-xfb94lq8	114	13	do	do	VB
cord-264532-xfb94lq8	114	14	no	no	RB
cord-264532-xfb94lq8	114	15	better	well	JJR
cord-264532-xfb94lq8	114	16	than	than	IN
cord-264532-xfb94lq8	114	17	adapt	adapt	VB
cord-264532-xfb94lq8	114	18	toward	toward	IN
cord-264532-xfb94lq8	114	19	the	the	DT
cord-264532-xfb94lq8	114	20	current	current	JJ
cord-264532-xfb94lq8	114	21	optimum	optimum	NN
cord-264532-xfb94lq8	114	22	.	.	.
cord-264532-xfb94lq8	115	1	Even	even	RB
cord-264532-xfb94lq8	115	2	in	in	IN
cord-264532-xfb94lq8	115	3	the	the	DT
cord-264532-xfb94lq8	115	4	absence	absence	NN
cord-264532-xfb94lq8	115	5	of	of	IN
cord-264532-xfb94lq8	115	6	this	this	DT
cord-264532-xfb94lq8	115	7	effect	effect	NN
cord-264532-xfb94lq8	115	8	,	,	,
cord-264532-xfb94lq8	115	9	parasite	parasite	NN
cord-264532-xfb94lq8	115	10	evolution	evolution	NN
cord-264532-xfb94lq8	115	11	may	may	MD
cord-264532-xfb94lq8	115	12	be	be	VB
cord-264532-xfb94lq8	115	13	slow	slow	JJ
cord-264532-xfb94lq8	115	14	to	to	TO
cord-264532-xfb94lq8	115	15	reach	reach	VB
cord-264532-xfb94lq8	115	16	the	the	DT
cord-264532-xfb94lq8	115	17	optimum	optimum	JJ
cord-264532-xfb94lq8	115	18	because	because	IN
cord-264532-xfb94lq8	115	19	of	of	IN
cord-264532-xfb94lq8	115	20	(	(	-LRB-
cord-264532-xfb94lq8	115	21	ii	ii	NN
cord-264532-xfb94lq8	115	22	)	)	-RRB-
cord-264532-xfb94lq8	115	23	,	,	,
cord-264532-xfb94lq8	115	24	pleiotropy	pleiotropy	NN
cord-264532-xfb94lq8	115	25	or	or	CC
cord-264532-xfb94lq8	115	26	genetic	genetic	JJ
cord-264532-xfb94lq8	115	27	covariances	covariance	NNS
cord-264532-xfb94lq8	115	28	.	.	.
cord-264532-xfb94lq8	116	1	Selection	selection	NN
cord-264532-xfb94lq8	116	2	favors	favor	VBZ
cord-264532-xfb94lq8	116	3	mutations	mutation	NNS
cord-264532-xfb94lq8	116	4	with	with	IN
cord-264532-xfb94lq8	116	5	a	a	DT
cord-264532-xfb94lq8	116	6	higher	high	JJR
cord-264532-xfb94lq8	116	7	fitness	fitness	NN
cord-264532-xfb94lq8	116	8	than	than	IN
cord-264532-xfb94lq8	116	9	the	the	DT
cord-264532-xfb94lq8	116	10	currently	currently	RB
cord-264532-xfb94lq8	116	11	dominant	dominant	JJ
cord-264532-xfb94lq8	116	12	strains	strain	NNS
cord-264532-xfb94lq8	116	13	.	.	.
cord-264532-xfb94lq8	117	1	These	these	DT
cord-264532-xfb94lq8	117	2	mutations	mutation	NNS
cord-264532-xfb94lq8	117	3	may	may	MD
cord-264532-xfb94lq8	117	4	improve	improve	VB
cord-264532-xfb94lq8	117	5	transmission	transmission	NN
cord-264532-xfb94lq8	117	6	but	but	CC
cord-264532-xfb94lq8	117	7	may	may	MD
cord-264532-xfb94lq8	117	8	result	result	VB
cord-264532-xfb94lq8	117	9	in	in	IN
cord-264532-xfb94lq8	117	10	virulence	virulence	NN
cord-264532-xfb94lq8	117	11	further	far	RBR
cord-264532-xfb94lq8	117	12	away	away	RB
cord-264532-xfb94lq8	117	13	from	from	IN
cord-264532-xfb94lq8	117	14	its	-PRON-	PRP$
cord-264532-xfb94lq8	117	15	optimum	optimum	NN
cord-264532-xfb94lq8	117	16	.	.	.
cord-264532-xfb94lq8	118	1	Fig	Fig	NNP
cord-264532-xfb94lq8	118	2	.	.	NNP
cord-264532-xfb94lq8	118	3	2	2	LS
cord-264532-xfb94lq8	118	4	(	(	-LRB-
cord-264532-xfb94lq8	118	5	bottom	bottom	NN
cord-264532-xfb94lq8	118	6	)	)	-RRB-
cord-264532-xfb94lq8	118	7	shows	show	VBZ
cord-264532-xfb94lq8	118	8	that	that	IN
cord-264532-xfb94lq8	118	9	fitness	fitness	NN
cord-264532-xfb94lq8	118	10	isoclines	isocline	NNS
cord-264532-xfb94lq8	118	11	run	run	VBP
cord-264532-xfb94lq8	118	12	parallel	parallel	RB
cord-264532-xfb94lq8	118	13	to	to	IN
cord-264532-xfb94lq8	118	14	the	the	DT
cord-264532-xfb94lq8	118	15	invasion	invasion	NN
cord-264532-xfb94lq8	118	16	boundary	boundary	NN
cord-264532-xfb94lq8	118	17	,	,	,
cord-264532-xfb94lq8	119	1	so	so	RB
cord-264532-xfb94lq8	119	2	all	all	DT
cord-264532-xfb94lq8	119	3	points	point	NNS
cord-264532-xfb94lq8	119	4	on	on	IN
cord-264532-xfb94lq8	119	5	a	a	DT
cord-264532-xfb94lq8	119	6	fitness	fitness	NN
cord-264532-xfb94lq8	119	7	isocline	isocline	NN
cord-264532-xfb94lq8	119	8	have	have	VBP
cord-264532-xfb94lq8	119	9	the	the	DT
cord-264532-xfb94lq8	119	10	same	same	JJ
cord-264532-xfb94lq8	119	11	fitness	fitness	NN
cord-264532-xfb94lq8	119	12	,	,	,
cord-264532-xfb94lq8	119	13	assuming	assume	VBG
cord-264532-xfb94lq8	119	14	that	that	IN
cord-264532-xfb94lq8	119	15	S	S	NNP
cord-264532-xfb94lq8	119	16	remains	remain	VBZ
cord-264532-xfb94lq8	119	17	constant	constant	JJ
cord-264532-xfb94lq8	119	18	.	.	.
cord-264532-xfb94lq8	120	1	As	as	IN
cord-264532-xfb94lq8	120	2	can	can	MD
cord-264532-xfb94lq8	120	3	be	be	VB
cord-264532-xfb94lq8	120	4	seen	see	VBN
cord-264532-xfb94lq8	120	5	for	for	IN
cord-264532-xfb94lq8	120	6	the	the	DT
cord-264532-xfb94lq8	120	7	trade	trade	NN
cord-264532-xfb94lq8	120	8	-	-	HYPH
cord-264532-xfb94lq8	120	9	off	off	RP
cord-264532-xfb94lq8	120	10	boundary	boundary	NN
cord-264532-xfb94lq8	120	11	drawn	draw	VBN
cord-264532-xfb94lq8	120	12	,	,	,
cord-264532-xfb94lq8	120	13	there	there	EX
cord-264532-xfb94lq8	120	14	is	be	VBZ
cord-264532-xfb94lq8	120	15	a	a	DT
cord-264532-xfb94lq8	120	16	wide	wide	JJ
cord-264532-xfb94lq8	120	17	range	range	NN
cord-264532-xfb94lq8	120	18	of	of	IN
cord-264532-xfb94lq8	120	19	virulence	virulence	NN
cord-264532-xfb94lq8	120	20	associated	associate	VBN
cord-264532-xfb94lq8	120	21	with	with	IN
cord-264532-xfb94lq8	120	22	each	each	DT
cord-264532-xfb94lq8	120	23	step	step	NN
cord-264532-xfb94lq8	120	24	of	of	IN
cord-264532-xfb94lq8	120	25	evolution	evolution	NN
cord-264532-xfb94lq8	120	26	toward	toward	IN
cord-264532-xfb94lq8	120	27	the	the	DT
cord-264532-xfb94lq8	120	28	optimum	optimum	NN
cord-264532-xfb94lq8	120	29	,	,	,
cord-264532-xfb94lq8	120	30	until	until	IN
cord-264532-xfb94lq8	120	31	the	the	DT
cord-264532-xfb94lq8	120	32	optimum	optimum	NN
cord-264532-xfb94lq8	120	33	is	be	VBZ
cord-264532-xfb94lq8	120	34	neared	near	VBN
cord-264532-xfb94lq8	120	35	(	(	-LRB-
cord-264532-xfb94lq8	120	36	depending	depend	VBG
cord-264532-xfb94lq8	120	37	on	on	IN
cord-264532-xfb94lq8	120	38	the	the	DT
cord-264532-xfb94lq8	120	39	shape	shape	NN
cord-264532-xfb94lq8	120	40	of	of	IN
cord-264532-xfb94lq8	120	41	the	the	DT
cord-264532-xfb94lq8	120	42	trade	trade	NN
cord-264532-xfb94lq8	120	43	-	-	HYPH
cord-264532-xfb94lq8	120	44	off	off	NN
cord-264532-xfb94lq8	120	45	)	)	-RRB-
cord-264532-xfb94lq8	120	46	.	.	.
cord-264532-xfb94lq8	121	1	Thus	thus	RB
cord-264532-xfb94lq8	121	2	,	,	,
cord-264532-xfb94lq8	121	3	particularly	particularly	RB
cord-264532-xfb94lq8	121	4	during	during	IN
cord-264532-xfb94lq8	121	5	the	the	DT
cord-264532-xfb94lq8	121	6	initial	initial	JJ
cord-264532-xfb94lq8	121	7	phases	phase	NNS
cord-264532-xfb94lq8	121	8	of	of	IN
cord-264532-xfb94lq8	121	9	invasion	invasion	NN
cord-264532-xfb94lq8	121	10	,	,	,
cord-264532-xfb94lq8	121	11	evolution	evolution	NN
cord-264532-xfb94lq8	121	12	of	of	IN
cord-264532-xfb94lq8	121	13	higher	high	JJR
cord-264532-xfb94lq8	121	14	parasite	parasite	NN
cord-264532-xfb94lq8	121	15	fitness	fitness	NN
cord-264532-xfb94lq8	121	16	need	nee	MD
cord-264532-xfb94lq8	121	17	not	not	RB
cord-264532-xfb94lq8	121	18	be	be	VB
cord-264532-xfb94lq8	121	19	accompanied	accompany	VBN
cord-264532-xfb94lq8	121	20	by	by	IN
cord-264532-xfb94lq8	121	21	a	a	DT
cord-264532-xfb94lq8	121	22	change	change	NN
cord-264532-xfb94lq8	121	23	in	in	IN
cord-264532-xfb94lq8	121	24	virulence	virulence	NN
cord-264532-xfb94lq8	121	25	.	.	.
cord-264532-xfb94lq8	122	1	Of	of	RB
cord-264532-xfb94lq8	122	2	course	course	RB
cord-264532-xfb94lq8	122	3	,	,	,
cord-264532-xfb94lq8	122	4	other	other	JJ
cord-264532-xfb94lq8	122	5	factors	factor	NNS
cord-264532-xfb94lq8	122	6	may	may	MD
cord-264532-xfb94lq8	122	7	also	also	RB
cord-264532-xfb94lq8	122	8	slow	slow	VB
cord-264532-xfb94lq8	122	9	the	the	DT
cord-264532-xfb94lq8	122	10	approach	approach	NN
cord-264532-xfb94lq8	122	11	to	to	IN
cord-264532-xfb94lq8	122	12	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	122	13	,	,	,
cord-264532-xfb94lq8	122	14	but	but	CC
cord-264532-xfb94lq8	122	15	these	these	DT
cord-264532-xfb94lq8	122	16	two	two	CD
cord-264532-xfb94lq8	122	17	follow	follow	VBP
cord-264532-xfb94lq8	122	18	directly	directly	RB
cord-264532-xfb94lq8	122	19	from	from	IN
cord-264532-xfb94lq8	122	20	our	-PRON-	PRP$
cord-264532-xfb94lq8	122	21	model	model	NN
cord-264532-xfb94lq8	122	22	.	.	.
cord-264532-xfb94lq8	123	1	The	the	DT
cord-264532-xfb94lq8	123	2	invasion	invasion	NN
cord-264532-xfb94lq8	123	3	threshold	threshold	NN
cord-264532-xfb94lq8	123	4	model	model	NN
cord-264532-xfb94lq8	123	5	has	have	VBZ
cord-264532-xfb94lq8	123	6	been	be	VBN
cord-264532-xfb94lq8	123	7	presented	present	VBN
cord-264532-xfb94lq8	123	8	as	as	IN
cord-264532-xfb94lq8	123	9	though	though	IN
cord-264532-xfb94lq8	123	10	the	the	DT
cord-264532-xfb94lq8	123	11	only	only	JJ
cord-264532-xfb94lq8	123	12	outcome	outcome	NN
cord-264532-xfb94lq8	123	13	of	of	IN
cord-264532-xfb94lq8	123	14	host	host	NN
cord-264532-xfb94lq8	123	15	infection	infection	NN
cord-264532-xfb94lq8	123	16	is	be	VBZ
cord-264532-xfb94lq8	123	17	death	death	NN
cord-264532-xfb94lq8	123	18	.	.	.
cord-264532-xfb94lq8	124	1	In	in	IN
cord-264532-xfb94lq8	124	2	such	such	PDT
cord-264532-xfb94lq8	124	3	a	a	DT
cord-264532-xfb94lq8	124	4	system	system	NN
cord-264532-xfb94lq8	124	5	,	,	,
cord-264532-xfb94lq8	124	6	the	the	DT
cord-264532-xfb94lq8	124	7	initial	initial	JJ
cord-264532-xfb94lq8	124	8	parasite	parasite	NN
cord-264532-xfb94lq8	124	9	invasion	invasion	NN
cord-264532-xfb94lq8	124	10	would	would	MD
cord-264532-xfb94lq8	124	11	be	be	VB
cord-264532-xfb94lq8	124	12	followed	follow	VBN
cord-264532-xfb94lq8	124	13	by	by	IN
cord-264532-xfb94lq8	124	14	a	a	DT
cord-264532-xfb94lq8	124	15	reduction	reduction	NN
cord-264532-xfb94lq8	124	16	in	in	IN
cord-264532-xfb94lq8	124	17	host	host	NN
cord-264532-xfb94lq8	124	18	density	density	NN
cord-264532-xfb94lq8	124	19	to	to	IN
cord-264532-xfb94lq8	124	20	the	the	DT
cord-264532-xfb94lq8	124	21	dynamic	dynamic	JJ
cord-264532-xfb94lq8	124	22	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	124	23	,	,	,
cord-264532-xfb94lq8	124	24	and	and	CC
cord-264532-xfb94lq8	124	25	the	the	DT
cord-264532-xfb94lq8	124	26	resulting	result	VBG
cord-264532-xfb94lq8	124	27	low	low	JJ
cord-264532-xfb94lq8	124	28	absolute	absolute	JJ
cord-264532-xfb94lq8	124	29	host	host	NN
cord-264532-xfb94lq8	124	30	density	density	NN
cord-264532-xfb94lq8	124	31	would	would	MD
cord-264532-xfb94lq8	124	32	greatly	greatly	RB
cord-264532-xfb94lq8	124	33	limit	limit	VB
cord-264532-xfb94lq8	124	34	opportunities	opportunity	NNS
cord-264532-xfb94lq8	124	35	for	for	IN
cord-264532-xfb94lq8	124	36	the	the	DT
cord-264532-xfb94lq8	124	37	re	re	NN
cord-264532-xfb94lq8	124	38	-	-	NN
cord-264532-xfb94lq8	124	39	invasion	invasion	NN
cord-264532-xfb94lq8	124	40	of	of	IN
cord-264532-xfb94lq8	124	41	any	any	DT
cord-264532-xfb94lq8	124	42	parasite	parasite	JJ
cord-264532-xfb94lq8	124	43	mutants	mutant	NNS
cord-264532-xfb94lq8	124	44	that	that	WDT
cord-264532-xfb94lq8	124	45	had	have	VBD
cord-264532-xfb94lq8	124	46	an	an	DT
cord-264532-xfb94lq8	124	47	even	even	RB
cord-264532-xfb94lq8	124	48	more	more	RBR
cord-264532-xfb94lq8	124	49	devastating	devastating	JJ
cord-264532-xfb94lq8	124	50	impact	impact	NN
cord-264532-xfb94lq8	124	51	on	on	IN
cord-264532-xfb94lq8	124	52	the	the	DT
cord-264532-xfb94lq8	124	53	host	host	NN
cord-264532-xfb94lq8	124	54	.	.	.
cord-264532-xfb94lq8	125	1	Yet	yet	RB
cord-264532-xfb94lq8	125	2	,	,	,
cord-264532-xfb94lq8	125	3	host	host	NN
cord-264532-xfb94lq8	125	4	death	death	NN
cord-264532-xfb94lq8	125	5	is	be	VBZ
cord-264532-xfb94lq8	125	6	not	not	RB
cord-264532-xfb94lq8	125	7	the	the	DT
cord-264532-xfb94lq8	125	8	only	only	JJ
cord-264532-xfb94lq8	125	9	outcome	outcome	NN
cord-264532-xfb94lq8	125	10	of	of	IN
cord-264532-xfb94lq8	125	11	infection	infection	NN
cord-264532-xfb94lq8	125	12	.	.	.
cord-264532-xfb94lq8	126	1	Recovery	recovery	NN
cord-264532-xfb94lq8	126	2	and	and	CC
cord-264532-xfb94lq8	126	3	consequent	consequent	JJ
cord-264532-xfb94lq8	126	4	immunity	immunity	NN
cord-264532-xfb94lq8	126	5	is	be	VBZ
cord-264532-xfb94lq8	126	6	typical	typical	JJ
cord-264532-xfb94lq8	126	7	of	of	IN
cord-264532-xfb94lq8	126	8	many	many	JJ
cord-264532-xfb94lq8	126	9	parasites	parasite	NNS
cord-264532-xfb94lq8	126	10	(	(	-LRB-
cord-264532-xfb94lq8	126	11	not	not	RB
cord-264532-xfb94lq8	126	12	necessarily	necessarily	RB
cord-264532-xfb94lq8	126	13	precluding	preclude	VBG
cord-264532-xfb94lq8	126	14	the	the	DT
cord-264532-xfb94lq8	126	15	death	death	NN
cord-264532-xfb94lq8	126	16	of	of	IN
cord-264532-xfb94lq8	126	17	some	some	DT
cord-264532-xfb94lq8	126	18	infected	infected	JJ
cord-264532-xfb94lq8	126	19	hosts	host	NNS
cord-264532-xfb94lq8	126	20	)	)	-RRB-
cord-264532-xfb94lq8	126	21	.	.	.
cord-264532-xfb94lq8	127	1	How	how	WRB
cord-264532-xfb94lq8	127	2	does	do	VBZ
cord-264532-xfb94lq8	127	3	recovery	recovery	NN
cord-264532-xfb94lq8	127	4	affect	affect	VB
cord-264532-xfb94lq8	127	5	our	-PRON-	PRP$
cord-264532-xfb94lq8	127	6	model	model	NN
cord-264532-xfb94lq8	127	7	?	?	.
cord-264532-xfb94lq8	128	1	Here	here	RB
cord-264532-xfb94lq8	128	2	,	,	,
cord-264532-xfb94lq8	128	3	we	-PRON-	PRP
cord-264532-xfb94lq8	128	4	restrict	restrict	VBP
cord-264532-xfb94lq8	128	5	ourselves	-PRON-	PRP
cord-264532-xfb94lq8	128	6	to	to	IN
cord-264532-xfb94lq8	128	7	the	the	DT
cord-264532-xfb94lq8	128	8	extreme	extreme	JJ
cord-264532-xfb94lq8	128	9	case	case	NN
cord-264532-xfb94lq8	128	10	that	that	DT
cord-264532-xfb94lq8	128	11	recovery	recovery	NN
cord-264532-xfb94lq8	128	12	is	be	VBZ
cord-264532-xfb94lq8	128	13	complete	complete	JJ
cord-264532-xfb94lq8	128	14	,	,	,
cord-264532-xfb94lq8	128	15	so	so	IN
cord-264532-xfb94lq8	128	16	that	that	IN
cord-264532-xfb94lq8	128	17	a	a	DT
cord-264532-xfb94lq8	128	18	recovered	recover	VBN
cord-264532-xfb94lq8	128	19	individual	individual	NN
cord-264532-xfb94lq8	128	20	can	can	MD
cord-264532-xfb94lq8	128	21	not	not	RB
cord-264532-xfb94lq8	128	22	be	be	VB
cord-264532-xfb94lq8	128	23	reinfected	reinfecte	VBN
cord-264532-xfb94lq8	128	24	by	by	IN
cord-264532-xfb94lq8	128	25	the	the	DT
cord-264532-xfb94lq8	128	26	same	same	JJ
cord-264532-xfb94lq8	128	27	strain	strain	NN
cord-264532-xfb94lq8	128	28	(	(	-LRB-
cord-264532-xfb94lq8	128	29	see	see	VB
cord-264532-xfb94lq8	128	30	van	van	NNP
cord-264532-xfb94lq8	128	31	Baalen	Baalen	NNP
cord-264532-xfb94lq8	128	32	1998	1998	CD
cord-264532-xfb94lq8	128	33	for	for	IN
cord-264532-xfb94lq8	128	34	models	model	NNS
cord-264532-xfb94lq8	128	35	of	of	IN
cord-264532-xfb94lq8	128	36	virulence	virulence	NN
cord-264532-xfb94lq8	128	37	evolution	evolution	NN
cord-264532-xfb94lq8	128	38	with	with	IN
cord-264532-xfb94lq8	128	39	partial	partial	JJ
cord-264532-xfb94lq8	128	40	recovery	recovery	NN
cord-264532-xfb94lq8	128	41	)	)	-RRB-
cord-264532-xfb94lq8	128	42	.	.	.
cord-264532-xfb94lq8	129	1	Most	most	RBS
cord-264532-xfb94lq8	129	2	basically	basically	RB
cord-264532-xfb94lq8	129	3	,	,	,
cord-264532-xfb94lq8	129	4	if	if	IN
cord-264532-xfb94lq8	129	5	a	a	DT
cord-264532-xfb94lq8	129	6	large	large	JJ
cord-264532-xfb94lq8	129	7	fraction	fraction	NN
cord-264532-xfb94lq8	129	8	of	of	IN
cord-264532-xfb94lq8	129	9	the	the	DT
cord-264532-xfb94lq8	129	10	host	host	NN
cord-264532-xfb94lq8	129	11	population	population	NN
cord-264532-xfb94lq8	129	12	is	be	VBZ
cord-264532-xfb94lq8	129	13	immune	immune	JJ
cord-264532-xfb94lq8	129	14	,	,	,
cord-264532-xfb94lq8	129	15	a	a	DT
cord-264532-xfb94lq8	129	16	large	large	JJ
cord-264532-xfb94lq8	129	17	advantage	advantage	NN
cord-264532-xfb94lq8	129	18	can	can	MD
cord-264532-xfb94lq8	129	19	be	be	VB
cord-264532-xfb94lq8	129	20	gained	gain	VBN
cord-264532-xfb94lq8	129	21	by	by	IN
cord-264532-xfb94lq8	129	22	parasite	parasite	NN
cord-264532-xfb94lq8	129	23	mutants	mutant	NNS
cord-264532-xfb94lq8	129	24	that	that	WDT
cord-264532-xfb94lq8	129	25	can	can	MD
cord-264532-xfb94lq8	129	26	overcome	overcome	VB
cord-264532-xfb94lq8	129	27	the	the	DT
cord-264532-xfb94lq8	129	28	host	host	NN
cord-264532-xfb94lq8	129	29	immunity	immunity	NN
cord-264532-xfb94lq8	129	30	but	but	CC
cord-264532-xfb94lq8	129	31	also	also	RB
cord-264532-xfb94lq8	129	32	retain	retain	VB
cord-264532-xfb94lq8	129	33	the	the	DT
cord-264532-xfb94lq8	129	34	ability	ability	NN
cord-264532-xfb94lq8	129	35	to	to	TO
cord-264532-xfb94lq8	129	36	infect	infect	VB
cord-264532-xfb94lq8	129	37	susceptible	susceptible	JJ
cord-264532-xfb94lq8	129	38	hosts	host	NNS
cord-264532-xfb94lq8	129	39	(	(	-LRB-
cord-264532-xfb94lq8	129	40	S	S	NNP
cord-264532-xfb94lq8	129	41	)	)	-RRB-
cord-264532-xfb94lq8	129	42	.	.	.
cord-264532-xfb94lq8	130	1	Those	those	DT
cord-264532-xfb94lq8	130	2	mutants	mutant	NNS
cord-264532-xfb94lq8	130	3	have	have	VBP
cord-264532-xfb94lq8	130	4	their	-PRON-	PRP$
cord-264532-xfb94lq8	130	5	own	own	JJ
cord-264532-xfb94lq8	130	6	invasion	invasion	NN
cord-264532-xfb94lq8	130	7	threshold	threshold	NN
cord-264532-xfb94lq8	130	8	,	,	,
cord-264532-xfb94lq8	130	9	and	and	CC
cord-264532-xfb94lq8	130	10	depending	depend	VBG
cord-264532-xfb94lq8	130	11	on	on	IN
cord-264532-xfb94lq8	130	12	their	-PRON-	PRP$
cord-264532-xfb94lq8	130	13	parameters	parameter	NNS
cord-264532-xfb94lq8	130	14	,	,	,
cord-264532-xfb94lq8	130	15	those	those	DT
cord-264532-xfb94lq8	130	16	constraints	constraint	NNS
cord-264532-xfb94lq8	130	17	may	may	MD
cord-264532-xfb94lq8	130	18	be	be	VB
cord-264532-xfb94lq8	130	19	much	much	RB
cord-264532-xfb94lq8	130	20	more	more	RBR
cord-264532-xfb94lq8	130	21	lenient	lenient	JJ
cord-264532-xfb94lq8	130	22	than	than	IN
cord-264532-xfb94lq8	130	23	the	the	DT
cord-264532-xfb94lq8	130	24	constraints	constraint	NNS
cord-264532-xfb94lq8	130	25	applying	apply	VBG
cord-264532-xfb94lq8	130	26	to	to	IN
cord-264532-xfb94lq8	130	27	parasites	parasite	NNS
cord-264532-xfb94lq8	130	28	unable	unable	JJ
cord-264532-xfb94lq8	130	29	to	to	TO
cord-264532-xfb94lq8	130	30	escape	escape	VB
cord-264532-xfb94lq8	130	31	host	host	NN
cord-264532-xfb94lq8	130	32	immunity	immunity	NN
cord-264532-xfb94lq8	130	33	(	(	-LRB-
cord-264532-xfb94lq8	130	34	Fig	Fig	NNP
cord-264532-xfb94lq8	130	35	.	.	.
cord-264532-xfb94lq8	130	36	3	3	CD
cord-264532-xfb94lq8	130	37	)	)	-RRB-
cord-264532-xfb94lq8	130	38	.	.	.
cord-264532-xfb94lq8	131	1	Thus	thus	RB
cord-264532-xfb94lq8	131	2	,	,	,
cord-264532-xfb94lq8	131	3	parasites	parasite	NNS
cord-264532-xfb94lq8	131	4	that	that	WDT
cord-264532-xfb94lq8	131	5	engender	engender	VBP
cord-264532-xfb94lq8	131	6	host	host	NN
cord-264532-xfb94lq8	131	7	immunity	immunity	NN
cord-264532-xfb94lq8	131	8	have	have	VBP
cord-264532-xfb94lq8	131	9	the	the	DT
cord-264532-xfb94lq8	131	10	potential	potential	NN
cord-264532-xfb94lq8	131	11	to	to	TO
cord-264532-xfb94lq8	131	12	cause	cause	VB
cord-264532-xfb94lq8	131	13	repeated	repeat	VBN
cord-264532-xfb94lq8	131	14	invasions	invasion	NNS
cord-264532-xfb94lq8	131	15	,	,	,
cord-264532-xfb94lq8	131	16	with	with	IN
cord-264532-xfb94lq8	131	17	potential	potential	JJ
cord-264532-xfb94lq8	131	18	high	high	JJ
cord-264532-xfb94lq8	131	19	and	and	CC
cord-264532-xfb94lq8	131	20	devastating	devastating	JJ
cord-264532-xfb94lq8	131	21	virulence	virulence	NN
cord-264532-xfb94lq8	131	22	each	each	DT
cord-264532-xfb94lq8	131	23	time	time	NN
cord-264532-xfb94lq8	131	24	.	.	.
cord-264532-xfb94lq8	132	1	The	the	DT
cord-264532-xfb94lq8	132	2	dynamics	dynamic	NNS
cord-264532-xfb94lq8	132	3	of	of	IN
cord-264532-xfb94lq8	132	4	this	this	DT
cord-264532-xfb94lq8	132	5	process	process	NN
cord-264532-xfb94lq8	132	6	are	be	VBP
cord-264532-xfb94lq8	132	7	sensitive	sensitive	JJ
cord-264532-xfb94lq8	132	8	to	to	IN
cord-264532-xfb94lq8	132	9	the	the	DT
cord-264532-xfb94lq8	132	10	nature	nature	NN
cord-264532-xfb94lq8	132	11	of	of	IN
cord-264532-xfb94lq8	132	12	host	host	NN
cord-264532-xfb94lq8	132	13	recovery	recovery	NN
cord-264532-xfb94lq8	132	14	and	and	CC
cord-264532-xfb94lq8	132	15	virulence	virulence	NN
cord-264532-xfb94lq8	132	16	,	,	,
cord-264532-xfb94lq8	132	17	however	however	RB
cord-264532-xfb94lq8	132	18	.	.	.
cord-264532-xfb94lq8	133	1	A	a	DT
cord-264532-xfb94lq8	133	2	highly	highly	RB
cord-264532-xfb94lq8	133	3	virulent	virulent	JJ
cord-264532-xfb94lq8	133	4	parasite	parasite	NN
cord-264532-xfb94lq8	133	5	(	(	-LRB-
cord-264532-xfb94lq8	133	6	most	most	JJS
cord-264532-xfb94lq8	133	7	infections	infection	NNS
cord-264532-xfb94lq8	133	8	lethal	lethal	JJ
cord-264532-xfb94lq8	133	9	)	)	-RRB-
cord-264532-xfb94lq8	133	10	that	that	WDT
cord-264532-xfb94lq8	133	11	reaches	reach	VBZ
cord-264532-xfb94lq8	133	12	high	high	JJ
cord-264532-xfb94lq8	133	13	abundance	abundance	NN
cord-264532-xfb94lq8	133	14	in	in	IN
cord-264532-xfb94lq8	133	15	the	the	DT
cord-264532-xfb94lq8	133	16	host	host	NN
cord-264532-xfb94lq8	133	17	population	population	NN
cord-264532-xfb94lq8	133	18	will	will	MD
cord-264532-xfb94lq8	133	19	crash	crash	VB
cord-264532-xfb94lq8	133	20	the	the	DT
cord-264532-xfb94lq8	133	21	host	host	NN
cord-264532-xfb94lq8	133	22	population	population	NN
cord-264532-xfb94lq8	133	23	and	and	CC
cord-264532-xfb94lq8	133	24	not	not	RB
cord-264532-xfb94lq8	133	25	leave	leave	VB
cord-264532-xfb94lq8	133	26	many	many	JJ
cord-264532-xfb94lq8	133	27	recovered	recover	VBN
cord-264532-xfb94lq8	133	28	hosts	host	NNS
cord-264532-xfb94lq8	133	29	,	,	,
cord-264532-xfb94lq8	133	30	at	at	IN
cord-264532-xfb94lq8	133	31	least	least	JJS
cord-264532-xfb94lq8	133	32	in	in	IN
cord-264532-xfb94lq8	133	33	the	the	DT
cord-264532-xfb94lq8	133	34	short	short	JJ
cord-264532-xfb94lq8	133	35	term	term	NN
cord-264532-xfb94lq8	133	36	.	.	.
cord-264532-xfb94lq8	134	1	Until	until	IN
cord-264532-xfb94lq8	134	2	host	host	NN
cord-264532-xfb94lq8	134	3	numbers	number	NNS
cord-264532-xfb94lq8	134	4	rebound	rebound	VBP
cord-264532-xfb94lq8	134	5	,	,	,
cord-264532-xfb94lq8	134	6	there	there	EX
cord-264532-xfb94lq8	134	7	would	would	MD
cord-264532-xfb94lq8	134	8	be	be	VB
cord-264532-xfb94lq8	134	9	little	little	JJ
cord-264532-xfb94lq8	134	10	opportunity	opportunity	NN
cord-264532-xfb94lq8	134	11	for	for	IN
cord-264532-xfb94lq8	134	12	new	new	JJ
cord-264532-xfb94lq8	134	13	parasite	parasite	NN
cord-264532-xfb94lq8	134	14	invasions	invasion	NNS
cord-264532-xfb94lq8	134	15	because	because	IN
cord-264532-xfb94lq8	134	16	of	of	IN
cord-264532-xfb94lq8	134	17	the	the	DT
cord-264532-xfb94lq8	134	18	low	low	JJ
cord-264532-xfb94lq8	134	19	absolute	absolute	JJ
cord-264532-xfb94lq8	134	20	density	density	NN
cord-264532-xfb94lq8	134	21	of	of	IN
cord-264532-xfb94lq8	134	22	hosts	host	NNS
cord-264532-xfb94lq8	134	23	.	.	.
cord-264532-xfb94lq8	135	1	If	if	IN
cord-264532-xfb94lq8	135	2	recovery	recovery	NN
cord-264532-xfb94lq8	135	3	rate	rate	NN
cord-264532-xfb94lq8	135	4	from	from	IN
cord-264532-xfb94lq8	135	5	infection	infection	NN
cord-264532-xfb94lq8	135	6	is	be	VBZ
cord-264532-xfb94lq8	135	7	instead	instead	RB
cord-264532-xfb94lq8	135	8	high	high	JJ
cord-264532-xfb94lq8	135	9	,	,	,
cord-264532-xfb94lq8	135	10	virulence	virulence	NN
cord-264532-xfb94lq8	135	11	(	(	-LRB-
cord-264532-xfb94lq8	135	12	host	host	NN
cord-264532-xfb94lq8	135	13	mortality	mortality	NN
cord-264532-xfb94lq8	135	14	)	)	-RRB-
cord-264532-xfb94lq8	135	15	is	be	VBZ
cord-264532-xfb94lq8	135	16	necessarily	necessarily	RB
cord-264532-xfb94lq8	135	17	low	low	JJ
cord-264532-xfb94lq8	135	18	,	,	,
cord-264532-xfb94lq8	135	19	and	and	CC
cord-264532-xfb94lq8	135	20	the	the	DT
cord-264532-xfb94lq8	135	21	parasite	parasite	JJ
cord-264532-xfb94lq8	135	22	impact	impact	NN
cord-264532-xfb94lq8	135	23	on	on	IN
cord-264532-xfb94lq8	135	24	host	host	NN
cord-264532-xfb94lq8	135	25	density	density	NN
cord-264532-xfb94lq8	135	26	will	will	MD
cord-264532-xfb94lq8	135	27	be	be	VB
cord-264532-xfb94lq8	135	28	slight	slight	JJ
cord-264532-xfb94lq8	135	29	.	.	.
cord-264532-xfb94lq8	136	1	In	in	IN
cord-264532-xfb94lq8	136	2	this	this	DT
cord-264532-xfb94lq8	136	3	latter	latter	JJ
cord-264532-xfb94lq8	136	4	case	case	NN
cord-264532-xfb94lq8	136	5	,	,	,
cord-264532-xfb94lq8	136	6	the	the	DT
cord-264532-xfb94lq8	136	7	host	host	NN
cord-264532-xfb94lq8	136	8	population	population	NN
cord-264532-xfb94lq8	136	9	is	be	VBZ
cord-264532-xfb94lq8	136	10	soon	soon	RB
cord-264532-xfb94lq8	136	11	prone	prone	JJ
cord-264532-xfb94lq8	136	12	to	to	IN
cord-264532-xfb94lq8	136	13	invasion	invasion	NN
cord-264532-xfb94lq8	136	14	of	of	IN
cord-264532-xfb94lq8	136	15	mutants	mutant	NNS
cord-264532-xfb94lq8	136	16	that	that	WDT
cord-264532-xfb94lq8	136	17	escape	escape	VBP
cord-264532-xfb94lq8	136	18	immunity	immunity	NN
cord-264532-xfb94lq8	136	19	.	.	.
cord-264532-xfb94lq8	137	1	Thus	thus	RB
cord-264532-xfb94lq8	137	2	epidemics	epidemic	NNS
cord-264532-xfb94lq8	137	3	that	that	WDT
cord-264532-xfb94lq8	137	4	kill	kill	VBP
cord-264532-xfb94lq8	137	5	large	large	JJ
cord-264532-xfb94lq8	137	6	numbers	number	NNS
cord-264532-xfb94lq8	137	7	of	of	IN
cord-264532-xfb94lq8	137	8	hosts	host	NNS
cord-264532-xfb94lq8	137	9	will	will	MD
cord-264532-xfb94lq8	137	10	experience	experience	VB
cord-264532-xfb94lq8	137	11	longer	long	RBR
cord-264532-xfb94lq8	137	12	lags	lag	VBZ
cord-264532-xfb94lq8	137	13	before	before	IN
cord-264532-xfb94lq8	137	14	possible	possible	JJ
cord-264532-xfb94lq8	137	15	reinvasion	reinvasion	NN
cord-264532-xfb94lq8	137	16	than	than	IN
cord-264532-xfb94lq8	137	17	epidemics	epidemic	NNS
cord-264532-xfb94lq8	137	18	that	that	WDT
cord-264532-xfb94lq8	137	19	do	do	VBP
cord-264532-xfb94lq8	137	20	not	not	RB
cord-264532-xfb94lq8	137	21	kill	kill	VB
cord-264532-xfb94lq8	137	22	many	many	JJ
cord-264532-xfb94lq8	137	23	hosts	host	NNS
cord-264532-xfb94lq8	137	24	.	.	.
cord-264532-xfb94lq8	138	1	The	the	DT
cord-264532-xfb94lq8	138	2	addition	addition	NN
cord-264532-xfb94lq8	138	3	of	of	IN
cord-264532-xfb94lq8	138	4	recovery	recovery	NN
cord-264532-xfb94lq8	138	5	does	do	VBZ
cord-264532-xfb94lq8	138	6	change	change	VB
cord-264532-xfb94lq8	138	7	the	the	DT
cord-264532-xfb94lq8	138	8	interpretation	interpretation	NN
cord-264532-xfb94lq8	138	9	of	of	IN
cord-264532-xfb94lq8	138	10	the	the	DT
cord-264532-xfb94lq8	138	11	preceding	precede	VBG
cord-264532-xfb94lq8	138	12	model	model	NN
cord-264532-xfb94lq8	138	13	somewhat	somewhat	RB
cord-264532-xfb94lq8	138	14	.	.	.
cord-264532-xfb94lq8	139	1	The	the	DT
cord-264532-xfb94lq8	139	2	derivations	derivation	NNS
cord-264532-xfb94lq8	139	3	above	above	RB
cord-264532-xfb94lq8	139	4	remain	remain	VBP
cord-264532-xfb94lq8	139	5	the	the	DT
cord-264532-xfb94lq8	139	6	same	same	JJ
cord-264532-xfb94lq8	139	7	,	,	,
cord-264532-xfb94lq8	139	8	but	but	CC
cord-264532-xfb94lq8	139	9	the	the	DT
cord-264532-xfb94lq8	139	10	d	d	NNP
cord-264532-xfb94lq8	139	11	term	term	NN
cord-264532-xfb94lq8	139	12	(	(	-LRB-
cord-264532-xfb94lq8	139	13	now	now	RB
cord-264532-xfb94lq8	139	14	denoted	denote	VBN
cord-264532-xfb94lq8	139	15	d¢	d¢	NN
cord-264532-xfb94lq8	139	16	)	)	-RRB-
cord-264532-xfb94lq8	140	1	is	be	VBZ
cord-264532-xfb94lq8	140	2	no	no	RB
cord-264532-xfb94lq8	140	3	longer	long	RBR
cord-264532-xfb94lq8	140	4	just	just	RB
cord-264532-xfb94lq8	140	5	host	host	NN
cord-264532-xfb94lq8	140	6	mortality	mortality	NN
cord-264532-xfb94lq8	140	7	.	.	.
cord-264532-xfb94lq8	141	1	Instead	instead	RB
cord-264532-xfb94lq8	141	2	,	,	,
cord-264532-xfb94lq8	141	3	the	the	DT
cord-264532-xfb94lq8	141	4	d	d	NN
cord-264532-xfb94lq8	141	5	terms	term	NNS
cord-264532-xfb94lq8	141	6	are	be	VBP
cord-264532-xfb94lq8	141	7	replaced	replace	VBN
cord-264532-xfb94lq8	141	8	by	by	IN
cord-264532-xfb94lq8	141	9	d¢	d¢	NNP
cord-264532-xfb94lq8	141	10	,	,	,
cord-264532-xfb94lq8	141	11	where	where	WRB
cord-264532-xfb94lq8	141	12	and	and	CC
cord-264532-xfb94lq8	141	13	q	q	NNP
cord-264532-xfb94lq8	141	14	is	be	VBZ
cord-264532-xfb94lq8	141	15	the	the	DT
cord-264532-xfb94lq8	141	16	recovery	recovery	NN
cord-264532-xfb94lq8	141	17	rate	rate	NN
cord-264532-xfb94lq8	141	18	of	of	IN
cord-264532-xfb94lq8	141	19	infected	infected	JJ
cord-264532-xfb94lq8	141	20	hosts	host	NNS
cord-264532-xfb94lq8	141	21	(	(	-LRB-
cord-264532-xfb94lq8	141	22	to	to	IN
cord-264532-xfb94lq8	141	23	a	a	DT
cord-264532-xfb94lq8	141	24	state	state	NN
cord-264532-xfb94lq8	141	25	in	in	IN
cord-264532-xfb94lq8	141	26	which	which	WDT
cord-264532-xfb94lq8	141	27	they	-PRON-	PRP
cord-264532-xfb94lq8	141	28	can	can	MD
cord-264532-xfb94lq8	141	29	no	no	RB
cord-264532-xfb94lq8	141	30	longer	longer	RB
cord-264532-xfb94lq8	141	31	be	be	VB
cord-264532-xfb94lq8	141	32	infected	infect	VBN
cord-264532-xfb94lq8	141	33	)	)	-RRB-
cord-264532-xfb94lq8	141	34	.	.	.
cord-264532-xfb94lq8	142	1	Thus	thus	RB
cord-264532-xfb94lq8	142	2	,	,	,
cord-264532-xfb94lq8	142	3	if	if	IN
cord-264532-xfb94lq8	142	4	recovery	recovery	NN
cord-264532-xfb94lq8	142	5	Figure	figure	NN
cord-264532-xfb94lq8	142	6	3	3	CD
cord-264532-xfb94lq8	142	7	A	a	DT
cord-264532-xfb94lq8	142	8	population	population	NN
cord-264532-xfb94lq8	142	9	with	with	IN
cord-264532-xfb94lq8	142	10	a	a	DT
cord-264532-xfb94lq8	142	11	high	high	JJ
cord-264532-xfb94lq8	142	12	density	density	NN
cord-264532-xfb94lq8	142	13	of	of	IN
cord-264532-xfb94lq8	142	14	recovered	recovered	JJ
cord-264532-xfb94lq8	142	15	hosts	host	NNS
cord-264532-xfb94lq8	142	16	is	be	VBZ
cord-264532-xfb94lq8	142	17	susceptible	susceptible	JJ
cord-264532-xfb94lq8	142	18	to	to	IN
cord-264532-xfb94lq8	142	19	invasion	invasion	NN
cord-264532-xfb94lq8	142	20	by	by	IN
cord-264532-xfb94lq8	142	21	highly	highly	RB
cord-264532-xfb94lq8	142	22	virulent	virulent	JJ
cord-264532-xfb94lq8	142	23	mutants	mutant	NNS
cord-264532-xfb94lq8	142	24	.	.	.
cord-264532-xfb94lq8	143	1	Once	once	RB
cord-264532-xfb94lq8	143	2	a	a	DT
cord-264532-xfb94lq8	143	3	parasite	parasite	NN
cord-264532-xfb94lq8	143	4	has	have	VBZ
cord-264532-xfb94lq8	143	5	evolved	evolve	VBN
cord-264532-xfb94lq8	143	6	close	close	JJ
cord-264532-xfb94lq8	143	7	to	to	IN
cord-264532-xfb94lq8	143	8	its	-PRON-	PRP$
cord-264532-xfb94lq8	143	9	optimum	optimum	NN
cord-264532-xfb94lq8	143	10	along	along	IN
cord-264532-xfb94lq8	143	11	the	the	DT
cord-264532-xfb94lq8	143	12	trade	trade	NN
cord-264532-xfb94lq8	143	13	-	-	HYPH
cord-264532-xfb94lq8	143	14	off	off	RP
cord-264532-xfb94lq8	143	15	boundary	boundary	NN
cord-264532-xfb94lq8	143	16	,	,	,
cord-264532-xfb94lq8	143	17	there	there	EX
cord-264532-xfb94lq8	143	18	will	will	MD
cord-264532-xfb94lq8	143	19	be	be	VB
cord-264532-xfb94lq8	143	20	only	only	RB
cord-264532-xfb94lq8	143	21	a	a	DT
cord-264532-xfb94lq8	143	22	small	small	JJ
cord-264532-xfb94lq8	143	23	set	set	NN
cord-264532-xfb94lq8	143	24	of	of	IN
cord-264532-xfb94lq8	143	25	mutants	mutant	NNS
cord-264532-xfb94lq8	143	26	that	that	WDT
cord-264532-xfb94lq8	143	27	can	can	MD
cord-264532-xfb94lq8	143	28	invade	invade	VB
cord-264532-xfb94lq8	143	29	,	,	,
cord-264532-xfb94lq8	143	30	because	because	IN
cord-264532-xfb94lq8	143	31	they	-PRON-	PRP
cord-264532-xfb94lq8	143	32	are	be	VBP
cord-264532-xfb94lq8	143	33	all	all	RB
cord-264532-xfb94lq8	143	34	subject	subject	JJ
cord-264532-xfb94lq8	143	35	to	to	IN
cord-264532-xfb94lq8	143	36	the	the	DT
cord-264532-xfb94lq8	143	37	same	same	JJ
cord-264532-xfb94lq8	143	38	constraints	constraint	NNS
cord-264532-xfb94lq8	143	39	,	,	,
cord-264532-xfb94lq8	143	40	provided	provide	VBN
cord-264532-xfb94lq8	143	41	they	-PRON-	PRP
cord-264532-xfb94lq8	143	42	can	can	MD
cord-264532-xfb94lq8	143	43	infect	infect	VB
cord-264532-xfb94lq8	143	44	only	only	RB
cord-264532-xfb94lq8	143	45	the	the	DT
cord-264532-xfb94lq8	143	46	susceptible	susceptible	JJ
cord-264532-xfb94lq8	143	47	hosts	host	NNS
cord-264532-xfb94lq8	143	48	;	;	:
cord-264532-xfb94lq8	143	49	the	the	DT
cord-264532-xfb94lq8	143	50	invasion	invasion	NN
cord-264532-xfb94lq8	143	51	threshold	threshold	NN
cord-264532-xfb94lq8	143	52	for	for	IN
cord-264532-xfb94lq8	143	53	those	those	DT
cord-264532-xfb94lq8	143	54	mutants	mutant	NNS
cord-264532-xfb94lq8	143	55	is	be	VBZ
cord-264532-xfb94lq8	143	56	a	a	DT
cord-264532-xfb94lq8	143	57	line	line	NN
cord-264532-xfb94lq8	143	58	of	of	IN
cord-264532-xfb94lq8	143	59	slope	slope	NN
cord-264532-xfb94lq8	143	60	S	s	NN
cord-264532-xfb94lq8	143	61	(	(	-LRB-
cord-264532-xfb94lq8	143	62	the	the	DT
cord-264532-xfb94lq8	143	63	rightmost	rightmost	JJ
cord-264532-xfb94lq8	143	64	line	line	NN
cord-264532-xfb94lq8	143	65	)	)	-RRB-
cord-264532-xfb94lq8	143	66	.	.	.
cord-264532-xfb94lq8	144	1	A	a	DT
cord-264532-xfb94lq8	144	2	mutant	mutant	JJ
cord-264532-xfb94lq8	144	3	capable	capable	JJ
cord-264532-xfb94lq8	144	4	of	of	IN
cord-264532-xfb94lq8	144	5	infecting	infect	VBG
cord-264532-xfb94lq8	144	6	both	both	CC
cord-264532-xfb94lq8	144	7	susceptible	susceptible	JJ
cord-264532-xfb94lq8	144	8	and	and	CC
cord-264532-xfb94lq8	144	9	recovered	recovered	JJ
cord-264532-xfb94lq8	144	10	hosts	host	NNS
cord-264532-xfb94lq8	144	11	will	will	MD
cord-264532-xfb94lq8	144	12	have	have	VB
cord-264532-xfb94lq8	144	13	a	a	DT
cord-264532-xfb94lq8	144	14	much	much	RB
cord-264532-xfb94lq8	144	15	larger	large	JJR
cord-264532-xfb94lq8	144	16	set	set	NN
cord-264532-xfb94lq8	144	17	of	of	IN
cord-264532-xfb94lq8	144	18	possible	possible	JJ
cord-264532-xfb94lq8	144	19	mutants	mutant	NNS
cord-264532-xfb94lq8	144	20	that	that	WDT
cord-264532-xfb94lq8	144	21	can	can	MD
cord-264532-xfb94lq8	144	22	invade	invade	VB
cord-264532-xfb94lq8	144	23	(	(	-LRB-
cord-264532-xfb94lq8	144	24	the	the	DT
cord-264532-xfb94lq8	144	25	invasion	invasion	NN
cord-264532-xfb94lq8	144	26	threshold	threshold	NN
cord-264532-xfb94lq8	144	27	is	be	VBZ
cord-264532-xfb94lq8	144	28	a	a	DT
cord-264532-xfb94lq8	144	29	line	line	NN
cord-264532-xfb94lq8	144	30	of	of	IN
cord-264532-xfb94lq8	144	31	slope	slope	NN
cord-264532-xfb94lq8	144	32	S+R	S+R	NNP
cord-264532-xfb94lq8	144	33	,	,	,
cord-264532-xfb94lq8	144	34	where	where	WRB
cord-264532-xfb94lq8	144	35	R	r	NN
cord-264532-xfb94lq8	144	36	is	be	VBZ
cord-264532-xfb94lq8	144	37	the	the	DT
cord-264532-xfb94lq8	144	38	density	density	NN
cord-264532-xfb94lq8	144	39	of	of	IN
cord-264532-xfb94lq8	144	40	recovered	recovered	JJ
cord-264532-xfb94lq8	144	41	hosts	host	NNS
cord-264532-xfb94lq8	144	42	,	,	,
cord-264532-xfb94lq8	144	43	hence	hence	RB
cord-264532-xfb94lq8	144	44	lies	lie	VBZ
cord-264532-xfb94lq8	144	45	to	to	IN
cord-264532-xfb94lq8	144	46	the	the	DT
cord-264532-xfb94lq8	144	47	left	left	NN
cord-264532-xfb94lq8	144	48	of	of	IN
cord-264532-xfb94lq8	144	49	the	the	DT
cord-264532-xfb94lq8	144	50	line	line	NN
cord-264532-xfb94lq8	144	51	of	of	IN
cord-264532-xfb94lq8	144	52	slope	slope	NN
cord-264532-xfb94lq8	144	53	S	S	NNP
cord-264532-xfb94lq8	144	54	)	)	-RRB-
cord-264532-xfb94lq8	144	55	and	and	CC
cord-264532-xfb94lq8	144	56	thus	thus	RB
cord-264532-xfb94lq8	144	57	have	have	VBP
cord-264532-xfb94lq8	144	58	greater	great	JJR
cord-264532-xfb94lq8	144	59	potential	potential	NN
cord-264532-xfb94lq8	144	60	to	to	TO
cord-264532-xfb94lq8	144	61	evolve	evolve	VB
cord-264532-xfb94lq8	144	62	nonoptimal	nonoptimal	JJ
cord-264532-xfb94lq8	144	63	virulence	virulence	NN
cord-264532-xfb94lq8	144	64	.	.	.
cord-264532-xfb94lq8	145	1	The	the	DT
cord-264532-xfb94lq8	145	2	graph	graph	NN
cord-264532-xfb94lq8	145	3	is	be	VBZ
cord-264532-xfb94lq8	145	4	the	the	DT
cord-264532-xfb94lq8	145	5	same	same	JJ
cord-264532-xfb94lq8	145	6	as	as	IN
cord-264532-xfb94lq8	145	7	in	in	IN
cord-264532-xfb94lq8	145	8	previous	previous	JJ
cord-264532-xfb94lq8	145	9	figures	figure	NNS
cord-264532-xfb94lq8	145	10	,	,	,
cord-264532-xfb94lq8	145	11	except	except	IN
cord-264532-xfb94lq8	145	12	that	that	IN
cord-264532-xfb94lq8	145	13	the	the	DT
cord-264532-xfb94lq8	145	14	vertical	vertical	JJ
cord-264532-xfb94lq8	145	15	axis	axis	NN
cord-264532-xfb94lq8	145	16	(	(	-LRB-
cord-264532-xfb94lq8	145	17	d¢	d¢	NNP
cord-264532-xfb94lq8	145	18	)	)	-RRB-
cord-264532-xfb94lq8	145	19	now	now	RB
cord-264532-xfb94lq8	145	20	includes	include	VBZ
cord-264532-xfb94lq8	145	21	the	the	DT
cord-264532-xfb94lq8	145	22	recovery	recovery	NN
cord-264532-xfb94lq8	145	23	rate	rate	NN
cord-264532-xfb94lq8	145	24	of	of	IN
cord-264532-xfb94lq8	145	25	infected	infected	JJ
cord-264532-xfb94lq8	145	26	hosts	host	NNS
cord-264532-xfb94lq8	145	27	as	as	RB
cord-264532-xfb94lq8	145	28	well	well	RB
cord-264532-xfb94lq8	145	29	as	as	IN
cord-264532-xfb94lq8	145	30	mortality	mortality	NN
cord-264532-xfb94lq8	145	31	rate	rate	NN
cord-264532-xfb94lq8	145	32	(	(	-LRB-
cord-264532-xfb94lq8	145	33	the	the	DT
cord-264532-xfb94lq8	145	34	d	d	NN
cord-264532-xfb94lq8	145	35	in	in	IN
cord-264532-xfb94lq8	145	36	previous	previous	JJ
cord-264532-xfb94lq8	145	37	figures	figure	NNS
cord-264532-xfb94lq8	145	38	was	be	VBD
cord-264532-xfb94lq8	145	39	just	just	RB
cord-264532-xfb94lq8	145	40	mortality	mortality	NN
cord-264532-xfb94lq8	145	41	rate	rate	NN
cord-264532-xfb94lq8	145	42	)	)	-RRB-
cord-264532-xfb94lq8	145	43	.	.	.
cord-264532-xfb94lq8	146	1	from	from	IN
cord-264532-xfb94lq8	146	2	infection	infection	NN
cord-264532-xfb94lq8	146	3	is	be	VBZ
cord-264532-xfb94lq8	146	4	allowed	allow	VBN
cord-264532-xfb94lq8	146	5	,	,	,
cord-264532-xfb94lq8	146	6	the	the	DT
cord-264532-xfb94lq8	146	7	derivations	derivation	NNS
cord-264532-xfb94lq8	146	8	and	and	CC
cord-264532-xfb94lq8	146	9	figures	figure	NNS
cord-264532-xfb94lq8	146	10	above	above	IN
cord-264532-xfb94lq8	146	11	merely	merely	RB
cord-264532-xfb94lq8	146	12	substitute	substitute	VBP
cord-264532-xfb94lq8	146	13	d¢	d¢	NN
cord-264532-xfb94lq8	146	14	for	for	IN
cord-264532-xfb94lq8	146	15	d	d	NN
cord-264532-xfb94lq8	146	16	,	,	,
cord-264532-xfb94lq8	146	17	and	and	CC
cord-264532-xfb94lq8	146	18	the	the	DT
cord-264532-xfb94lq8	146	19	trade	trade	NN
cord-264532-xfb94lq8	146	20	-	-	HYPH
cord-264532-xfb94lq8	146	21	off	off	NN
cord-264532-xfb94lq8	146	22	functions	function	NNS
cord-264532-xfb94lq8	146	23	now	now	RB
cord-264532-xfb94lq8	146	24	combine	combine	VBP
cord-264532-xfb94lq8	146	25	recovery	recovery	NN
cord-264532-xfb94lq8	146	26	with	with	IN
cord-264532-xfb94lq8	146	27	virulence	virulence	NN
cord-264532-xfb94lq8	146	28	,	,	,
cord-264532-xfb94lq8	146	29	as	as	IN
cord-264532-xfb94lq8	146	30	shown	show	VBN
cord-264532-xfb94lq8	146	31	in	in	IN
cord-264532-xfb94lq8	146	32	Fig	Fig	NNP
cord-264532-xfb94lq8	146	33	.	.	.
cord-264532-xfb94lq8	147	1	3	3	LS
cord-264532-xfb94lq8	147	2	.	.	.
cord-264532-xfb94lq8	148	1	On	on	IN
cord-264532-xfb94lq8	148	2	intuitive	intuitive	JJ
cord-264532-xfb94lq8	148	3	grounds	ground	NNS
cord-264532-xfb94lq8	148	4	,	,	,
cord-264532-xfb94lq8	148	5	parasite	parasite	NN
cord-264532-xfb94lq8	148	6	dynamics	dynamic	NNS
cord-264532-xfb94lq8	148	7	are	be	VBP
cord-264532-xfb94lq8	148	8	sensitive	sensitive	JJ
cord-264532-xfb94lq8	148	9	to	to	IN
cord-264532-xfb94lq8	148	10	the	the	DT
cord-264532-xfb94lq8	148	11	loss	loss	NN
cord-264532-xfb94lq8	148	12	of	of	IN
cord-264532-xfb94lq8	148	13	infected	infected	JJ
cord-264532-xfb94lq8	148	14	hosts	host	NNS
cord-264532-xfb94lq8	148	15	,	,	,
cord-264532-xfb94lq8	148	16	but	but	CC
cord-264532-xfb94lq8	148	17	it	-PRON-	PRP
cord-264532-xfb94lq8	148	18	does	do	VBZ
cord-264532-xfb94lq8	148	19	not	not	RB
cord-264532-xfb94lq8	148	20	matter	matter	VB
cord-264532-xfb94lq8	148	21	whether	whether	IN
cord-264532-xfb94lq8	148	22	those	those	DT
cord-264532-xfb94lq8	148	23	infections	infection	NNS
cord-264532-xfb94lq8	148	24	are	be	VBP
cord-264532-xfb94lq8	148	25	lost	lose	VBN
cord-264532-xfb94lq8	148	26	because	because	IN
cord-264532-xfb94lq8	148	27	the	the	DT
cord-264532-xfb94lq8	148	28	host	host	NN
cord-264532-xfb94lq8	148	29	died	die	VBD
cord-264532-xfb94lq8	148	30	or	or	CC
cord-264532-xfb94lq8	148	31	because	because	IN
cord-264532-xfb94lq8	148	32	it	-PRON-	PRP
cord-264532-xfb94lq8	148	33	recovered	recover	VBD
cord-264532-xfb94lq8	148	34	.	.	.
cord-264532-xfb94lq8	149	1	The	the	DT
cord-264532-xfb94lq8	149	2	main	main	JJ
cord-264532-xfb94lq8	149	3	implication	implication	NN
cord-264532-xfb94lq8	149	4	of	of	IN
cord-264532-xfb94lq8	149	5	this	this	DT
cord-264532-xfb94lq8	149	6	change	change	NN
cord-264532-xfb94lq8	149	7	for	for	IN
cord-264532-xfb94lq8	149	8	evolution	evolution	NN
cord-264532-xfb94lq8	149	9	of	of	IN
cord-264532-xfb94lq8	149	10	virulence	virulence	NN
cord-264532-xfb94lq8	149	11	theories	theory	NNS
cord-264532-xfb94lq8	149	12	is	be	VBZ
cord-264532-xfb94lq8	149	13	that	that	IN
cord-264532-xfb94lq8	149	14	evolution	evolution	NN
cord-264532-xfb94lq8	149	15	of	of	IN
cord-264532-xfb94lq8	149	16	higher	high	JJR
cord-264532-xfb94lq8	149	17	d¢	d¢	NN
cord-264532-xfb94lq8	149	18	no	no	RB
cord-264532-xfb94lq8	149	19	longer	long	RBR
cord-264532-xfb94lq8	149	20	implies	imply	VBZ
cord-264532-xfb94lq8	149	21	evolution	evolution	NN
cord-264532-xfb94lq8	149	22	of	of	IN
cord-264532-xfb94lq8	149	23	higher	high	JJR
cord-264532-xfb94lq8	149	24	virulence	virulence	NN
cord-264532-xfb94lq8	149	25	.	.	.
cord-264532-xfb94lq8	150	1	Without	without	IN
cord-264532-xfb94lq8	150	2	specifying	specify	VBG
cord-264532-xfb94lq8	150	3	the	the	DT
cord-264532-xfb94lq8	150	4	relationship	relationship	NN
cord-264532-xfb94lq8	150	5	between	between	IN
cord-264532-xfb94lq8	150	6	virulence	virulence	NN
cord-264532-xfb94lq8	150	7	and	and	CC
cord-264532-xfb94lq8	150	8	recovery	recovery	NN
cord-264532-xfb94lq8	150	9	,	,	,
cord-264532-xfb94lq8	150	10	higher	high	JJR
cord-264532-xfb94lq8	150	11	d¢	d¢	NN
cord-264532-xfb94lq8	150	12	could	could	MD
cord-264532-xfb94lq8	150	13	mean	mean	VB
cord-264532-xfb94lq8	150	14	a	a	DT
cord-264532-xfb94lq8	150	15	higher	high	JJR
cord-264532-xfb94lq8	150	16	recovery	recovery	NN
cord-264532-xfb94lq8	150	17	rate	rate	NN
cord-264532-xfb94lq8	150	18	,	,	,
cord-264532-xfb94lq8	150	19	with	with	IN
cord-264532-xfb94lq8	150	20	no	no	DT
cord-264532-xfb94lq8	150	21	change	change	NN
cord-264532-xfb94lq8	150	22	in	in	IN
cord-264532-xfb94lq8	150	23	virulence	virulence	NN
cord-264532-xfb94lq8	150	24	or	or	CC
cord-264532-xfb94lq8	150	25	even	even	RB
cord-264532-xfb94lq8	150	26	a	a	DT
cord-264532-xfb94lq8	150	27	decline	decline	NN
cord-264532-xfb94lq8	150	28	in	in	IN
cord-264532-xfb94lq8	150	29	virulence	virulence	NN
cord-264532-xfb94lq8	150	30	(	(	-LRB-
cord-264532-xfb94lq8	150	31	Fig	Fig	NNP
cord-264532-xfb94lq8	150	32	.	.	.
cord-264532-xfb94lq8	150	33	4	4	CD
cord-264532-xfb94lq8	150	34	)	)	-RRB-
cord-264532-xfb94lq8	150	35	.	.	.
cord-264532-xfb94lq8	151	1	This	this	DT
cord-264532-xfb94lq8	151	2	indeterminacy	indeterminacy	NN
cord-264532-xfb94lq8	151	3	applies	apply	VBZ
cord-264532-xfb94lq8	151	4	to	to	IN
cord-264532-xfb94lq8	151	5	all	all	DT
cord-264532-xfb94lq8	151	6	evolution	evolution	NN
cord-264532-xfb94lq8	151	7	of	of	IN
cord-264532-xfb94lq8	151	8	virulence	virulence	NN
cord-264532-xfb94lq8	151	9	theories	theory	NNS
cord-264532-xfb94lq8	151	10	,	,	,
cord-264532-xfb94lq8	151	11	and	and	CC
cord-264532-xfb94lq8	151	12	it	-PRON-	PRP
cord-264532-xfb94lq8	151	13	is	be	VBZ
cord-264532-xfb94lq8	151	14	not	not	RB
cord-264532-xfb94lq8	151	15	otherwise	otherwise	RB
cord-264532-xfb94lq8	151	16	possible	possible	JJ
cord-264532-xfb94lq8	151	17	to	to	TO
cord-264532-xfb94lq8	151	18	predict	predict	VB
cord-264532-xfb94lq8	151	19	an	an	DT
cord-264532-xfb94lq8	151	20	optimum	optimum	JJ
cord-264532-xfb94lq8	151	21	virulence	virulence	NN
cord-264532-xfb94lq8	151	22	per	per	FW
cord-264532-xfb94lq8	151	23	se	se	FW
cord-264532-xfb94lq8	151	24	when	when	WRB
cord-264532-xfb94lq8	151	25	recovery	recovery	NN
cord-264532-xfb94lq8	151	26	is	be	VBZ
cord-264532-xfb94lq8	151	27	involved	involve	VBN
cord-264532-xfb94lq8	151	28	in	in	IN
cord-264532-xfb94lq8	151	29	the	the	DT
cord-264532-xfb94lq8	151	30	trade	trade	NN
cord-264532-xfb94lq8	151	31	-	-	HYPH
cord-264532-xfb94lq8	151	32	off	off	NN
cord-264532-xfb94lq8	151	33	with	with	IN
cord-264532-xfb94lq8	151	34	virulence	virulence	NN
cord-264532-xfb94lq8	151	35	.	.	.
cord-264532-xfb94lq8	152	1	The	the	DT
cord-264532-xfb94lq8	152	2	indeterminacy	indeterminacy	NN
cord-264532-xfb94lq8	152	3	poses	pose	VBZ
cord-264532-xfb94lq8	152	4	little	little	JJ
cord-264532-xfb94lq8	152	5	problem	problem	NN
cord-264532-xfb94lq8	152	6	for	for	IN
cord-264532-xfb94lq8	152	7	the	the	DT
cord-264532-xfb94lq8	152	8	invasion	invasion	NN
cord-264532-xfb94lq8	152	9	threshold	threshold	NN
cord-264532-xfb94lq8	152	10	perspective	perspective	NN
cord-264532-xfb94lq8	152	11	,	,	,
cord-264532-xfb94lq8	152	12	however	however	RB
cord-264532-xfb94lq8	152	13	:	:	:
cord-264532-xfb94lq8	152	14	the	the	DT
cord-264532-xfb94lq8	152	15	invasion	invasion	NN
cord-264532-xfb94lq8	152	16	threshold	threshold	NN
cord-264532-xfb94lq8	152	17	perspective	perspective	NN
cord-264532-xfb94lq8	152	18	merely	merely	RB
cord-264532-xfb94lq8	152	19	specifies	specify	VBZ
cord-264532-xfb94lq8	152	20	a	a	DT
cord-264532-xfb94lq8	152	21	range	range	NN
cord-264532-xfb94lq8	152	22	of	of	IN
cord-264532-xfb94lq8	152	23	possible	possible	JJ
cord-264532-xfb94lq8	152	24	virulence	virulence	NN
cord-264532-xfb94lq8	152	25	levels	level	NNS
cord-264532-xfb94lq8	152	26	that	that	WDT
cord-264532-xfb94lq8	152	27	can	can	MD
cord-264532-xfb94lq8	152	28	potentially	potentially	RB
cord-264532-xfb94lq8	152	29	invade	invade	VB
cord-264532-xfb94lq8	152	30	.	.	.
cord-264532-xfb94lq8	153	1	This	this	DT
cord-264532-xfb94lq8	153	2	range	range	NN
cord-264532-xfb94lq8	153	3	may	may	MD
cord-264532-xfb94lq8	153	4	be	be	VB
cord-264532-xfb94lq8	153	5	reduced	reduce	VBN
cord-264532-xfb94lq8	153	6	by	by	IN
cord-264532-xfb94lq8	153	7	the	the	DT
cord-264532-xfb94lq8	153	8	inclusion	inclusion	NN
cord-264532-xfb94lq8	153	9	of	of	IN
cord-264532-xfb94lq8	153	10	recovery	recovery	NN
cord-264532-xfb94lq8	153	11	,	,	,
cord-264532-xfb94lq8	153	12	but	but	CC
cord-264532-xfb94lq8	153	13	it	-PRON-	PRP
cord-264532-xfb94lq8	153	14	will	will	MD
cord-264532-xfb94lq8	153	15	always	always	RB
cord-264532-xfb94lq8	153	16	be	be	VB
cord-264532-xfb94lq8	153	17	wider	wide	JJR
cord-264532-xfb94lq8	153	18	than	than	IN
cord-264532-xfb94lq8	153	19	the	the	DT
cord-264532-xfb94lq8	153	20	range	range	NN
cord-264532-xfb94lq8	153	21	spanned	span	VBN
cord-264532-xfb94lq8	153	22	by	by	IN
cord-264532-xfb94lq8	153	23	the	the	DT
cord-264532-xfb94lq8	153	24	optima	optima	NNP
cord-264532-xfb94lq8	153	25	.	.	.
cord-264532-xfb94lq8	154	1	Before	before	IN
cord-264532-xfb94lq8	154	2	proceeding	proceed	VBG
cord-264532-xfb94lq8	154	3	to	to	IN
cord-264532-xfb94lq8	154	4	empirical	empirical	JJ
cord-264532-xfb94lq8	154	5	examples	example	NNS
cord-264532-xfb94lq8	154	6	,	,	,
cord-264532-xfb94lq8	154	7	it	-PRON-	PRP
cord-264532-xfb94lq8	154	8	is	be	VBZ
cord-264532-xfb94lq8	154	9	useful	useful	JJ
cord-264532-xfb94lq8	154	10	to	to	TO
cord-264532-xfb94lq8	154	11	consider	consider	VB
cord-264532-xfb94lq8	154	12	the	the	DT
cord-264532-xfb94lq8	154	13	distinction	distinction	NN
cord-264532-xfb94lq8	154	14	between	between	IN
cord-264532-xfb94lq8	154	15	the	the	DT
cord-264532-xfb94lq8	154	16	standard	standard	JJ
cord-264532-xfb94lq8	154	17	R	r	NN
cord-264532-xfb94lq8	154	18	0	0	CD
cord-264532-xfb94lq8	154	19	maximization	maximization	NN
cord-264532-xfb94lq8	154	20	model	model	NN
cord-264532-xfb94lq8	154	21	,	,	,
cord-264532-xfb94lq8	154	22	the	the	DT
cord-264532-xfb94lq8	154	23	Lenski	Lenski	NNP
cord-264532-xfb94lq8	154	24	and	and	CC
cord-264532-xfb94lq8	154	25	May	May	NNP
cord-264532-xfb94lq8	154	26	's	's	POS
cord-264532-xfb94lq8	154	27	(	(	-LRB-
cord-264532-xfb94lq8	154	28	1994	1994	CD
cord-264532-xfb94lq8	154	29	)	)	-RRB-
cord-264532-xfb94lq8	154	30	dynamic	dynamic	JJ
cord-264532-xfb94lq8	154	31	optimum	optimum	JJ
cord-264532-xfb94lq8	154	32	model	model	NN
cord-264532-xfb94lq8	154	33	,	,	,
cord-264532-xfb94lq8	154	34	and	and	CC
cord-264532-xfb94lq8	154	35	invasion	invasion	NN
cord-264532-xfb94lq8	154	36	threshold	threshold	NN
cord-264532-xfb94lq8	154	37	as	as	IN
cord-264532-xfb94lq8	154	38	alternative	alternative	JJ
cord-264532-xfb94lq8	154	39	perspectives	perspective	NNS
cord-264532-xfb94lq8	154	40	on	on	IN
cord-264532-xfb94lq8	154	41	the	the	DT
cord-264532-xfb94lq8	154	42	evolution	evolution	NN
cord-264532-xfb94lq8	154	43	of	of	IN
cord-264532-xfb94lq8	154	44	virulence	virulence	NN
cord-264532-xfb94lq8	154	45	.	.	.
cord-264532-xfb94lq8	155	1	There	there	EX
cord-264532-xfb94lq8	155	2	is	be	VBZ
cord-264532-xfb94lq8	155	3	obvious	obvious	JJ
cord-264532-xfb94lq8	155	4	overlap	overlap	NN
cord-264532-xfb94lq8	155	5	among	among	IN
cord-264532-xfb94lq8	155	6	these	these	DT
cord-264532-xfb94lq8	155	7	models	model	NNS
cord-264532-xfb94lq8	155	8	(	(	-LRB-
cord-264532-xfb94lq8	155	9	and	and	CC
cord-264532-xfb94lq8	155	10	both	both	DT
cord-264532-xfb94lq8	155	11	are	be	VBP
cord-264532-xfb94lq8	155	12	nicely	nicely	RB
cord-264532-xfb94lq8	155	13	subsumed	subsume	VBN
cord-264532-xfb94lq8	155	14	in	in	IN
cord-264532-xfb94lq8	155	15	the	the	DT
cord-264532-xfb94lq8	155	16	covariance	covariance	NN
cord-264532-xfb94lq8	155	17	method	method	NN
cord-264532-xfb94lq8	155	18	of	of	IN
cord-264532-xfb94lq8	155	19	Day	Day	NNP
cord-264532-xfb94lq8	155	20	and	and	CC
cord-264532-xfb94lq8	155	21	Gandon	Gandon	NNP
cord-264532-xfb94lq8	155	22	2006	2006	CD
cord-264532-xfb94lq8	155	23	)	)	-RRB-
cord-264532-xfb94lq8	155	24	,	,	,
cord-264532-xfb94lq8	155	25	but	but	CC
cord-264532-xfb94lq8	155	26	the	the	DT
cord-264532-xfb94lq8	155	27	emphases	emphasis	NNS
cord-264532-xfb94lq8	155	28	from	from	IN
cord-264532-xfb94lq8	155	29	them	-PRON-	PRP
cord-264532-xfb94lq8	155	30	have	have	VBP
cord-264532-xfb94lq8	155	31	differed	differ	VBN
cord-264532-xfb94lq8	155	32	.	.	.
cord-264532-xfb94lq8	156	1	The	the	DT
cord-264532-xfb94lq8	156	2	R	r	NN
cord-264532-xfb94lq8	156	3	0	0	CD
cord-264532-xfb94lq8	156	4	maximization	maximization	NN
cord-264532-xfb94lq8	156	5	model	model	NN
cord-264532-xfb94lq8	156	6	offers	offer	VBZ
cord-264532-xfb94lq8	156	7	a	a	DT
cord-264532-xfb94lq8	156	8	single	single	JJ
cord-264532-xfb94lq8	156	9	optimum	optimum	NN
cord-264532-xfb94lq8	156	10	,	,	,
cord-264532-xfb94lq8	156	11	albeit	albeit	IN
cord-264532-xfb94lq8	156	12	one	one	CD
cord-264532-xfb94lq8	156	13	that	that	WDT
cord-264532-xfb94lq8	156	14	may	may	MD
cord-264532-xfb94lq8	156	15	be	be	VB
cord-264532-xfb94lq8	156	16	sensitive	sensitive	JJ
cord-264532-xfb94lq8	156	17	to	to	IN
cord-264532-xfb94lq8	156	18	environmental	environmental	JJ
cord-264532-xfb94lq8	156	19	conditions	condition	NNS
cord-264532-xfb94lq8	156	20	.	.	.
cord-264532-xfb94lq8	157	1	It	-PRON-	PRP
cord-264532-xfb94lq8	157	2	assumes	assume	VBZ
cord-264532-xfb94lq8	157	3	dynamic	dynamic	JJ
cord-264532-xfb94lq8	157	4	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	157	5	exists	exist	VBZ
cord-264532-xfb94lq8	157	6	between	between	IN
cord-264532-xfb94lq8	157	7	host	host	NN
cord-264532-xfb94lq8	157	8	and	and	CC
cord-264532-xfb94lq8	157	9	parasite	parasite	NN
cord-264532-xfb94lq8	157	10	,	,	,
cord-264532-xfb94lq8	157	11	hence	hence	RB
cord-264532-xfb94lq8	157	12	does	do	VBZ
cord-264532-xfb94lq8	157	13	not	not	RB
cord-264532-xfb94lq8	157	14	apply	apply	VB
cord-264532-xfb94lq8	157	15	when	when	WRB
cord-264532-xfb94lq8	157	16	new	new	JJ
cord-264532-xfb94lq8	157	17	parasite	parasite	NN
cord-264532-xfb94lq8	157	18	mutants	mutant	NNS
cord-264532-xfb94lq8	157	19	invade	invade	VBP
cord-264532-xfb94lq8	157	20	.	.	.
cord-264532-xfb94lq8	158	1	The	the	DT
cord-264532-xfb94lq8	158	2	other	other	JJ
cord-264532-xfb94lq8	158	3	two	two	CD
cord-264532-xfb94lq8	158	4	models	model	NNS
cord-264532-xfb94lq8	158	5	,	,	,
cord-264532-xfb94lq8	158	6	Lenski	Lenski	NNP
cord-264532-xfb94lq8	158	7	-	-	HYPH
cord-264532-xfb94lq8	158	8	May	May	NNP
cord-264532-xfb94lq8	158	9	dynamic	dynamic	JJ
cord-264532-xfb94lq8	158	10	optimum	optimum	NN
cord-264532-xfb94lq8	158	11	and	and	CC
cord-264532-xfb94lq8	158	12	the	the	DT
cord-264532-xfb94lq8	158	13	invasion	invasion	NN
cord-264532-xfb94lq8	158	14	threshold	threshold	NN
cord-264532-xfb94lq8	158	15	,	,	,
cord-264532-xfb94lq8	158	16	are	be	VBP
cord-264532-xfb94lq8	158	17	similar	similar	JJ
cord-264532-xfb94lq8	158	18	in	in	IN
cord-264532-xfb94lq8	158	19	that	that	IN
cord-264532-xfb94lq8	158	20	both	both	DT
cord-264532-xfb94lq8	158	21	apply	apply	VBP
cord-264532-xfb94lq8	158	22	to	to	IN
cord-264532-xfb94lq8	158	23	invasions	invasion	NNS
cord-264532-xfb94lq8	158	24	.	.	.
cord-264532-xfb94lq8	159	1	The	the	DT
cord-264532-xfb94lq8	159	2	only	only	JJ
cord-264532-xfb94lq8	159	3	difference	difference	NN
cord-264532-xfb94lq8	159	4	is	be	VBZ
cord-264532-xfb94lq8	159	5	that	that	DT
cord-264532-xfb94lq8	159	6	one	one	PRP
cord-264532-xfb94lq8	159	7	emphasizes	emphasize	VBZ
cord-264532-xfb94lq8	159	8	the	the	DT
cord-264532-xfb94lq8	159	9	change	change	NN
cord-264532-xfb94lq8	159	10	of	of	IN
cord-264532-xfb94lq8	159	11	virulence	virulence	NN
cord-264532-xfb94lq8	159	12	optima	optima	NNP
cord-264532-xfb94lq8	159	13	during	during	IN
cord-264532-xfb94lq8	159	14	the	the	DT
cord-264532-xfb94lq8	159	15	invasion	invasion	NN
cord-264532-xfb94lq8	159	16	,	,	,
cord-264532-xfb94lq8	159	17	the	the	DT
cord-264532-xfb94lq8	159	18	other	other	JJ
cord-264532-xfb94lq8	159	19	addresses	address	VBZ
cord-264532-xfb94lq8	159	20	the	the	DT
cord-264532-xfb94lq8	159	21	range	range	NN
cord-264532-xfb94lq8	159	22	of	of	IN
cord-264532-xfb94lq8	159	23	virulence	virulence	NN
cord-264532-xfb94lq8	159	24	values	value	NNS
cord-264532-xfb94lq8	159	25	that	that	WDT
cord-264532-xfb94lq8	159	26	can	can	MD
cord-264532-xfb94lq8	159	27	invade	invade	VB
cord-264532-xfb94lq8	159	28	and	and	CC
cord-264532-xfb94lq8	159	29	the	the	DT
cord-264532-xfb94lq8	159	30	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	159	31	states	state	NNS
cord-264532-xfb94lq8	159	32	that	that	WDT
cord-264532-xfb94lq8	159	33	may	may	MD
cord-264532-xfb94lq8	159	34	persist	persist	VB
cord-264532-xfb94lq8	159	35	after	after	IN
cord-264532-xfb94lq8	159	36	invasion	invasion	NN
cord-264532-xfb94lq8	159	37	.	.	.
cord-264532-xfb94lq8	160	1	Without	without	IN
cord-264532-xfb94lq8	160	2	knowing	know	VBG
cord-264532-xfb94lq8	160	3	the	the	DT
cord-264532-xfb94lq8	160	4	optima	optima	NNP
cord-264532-xfb94lq8	160	5	,	,	,
cord-264532-xfb94lq8	160	6	the	the	DT
cord-264532-xfb94lq8	160	7	Lenski	Lenski	NNP
cord-264532-xfb94lq8	160	8	-	-	HYPH
cord-264532-xfb94lq8	160	9	May	May	NNP
cord-264532-xfb94lq8	160	10	and	and	CC
cord-264532-xfb94lq8	160	11	invasion	invasion	NN
cord-264532-xfb94lq8	160	12	threshold	threshold	NN
cord-264532-xfb94lq8	160	13	perspectives	perspective	NNS
cord-264532-xfb94lq8	160	14	are	be	VBP
cord-264532-xfb94lq8	160	15	difficult	difficult	JJ
cord-264532-xfb94lq8	160	16	to	to	TO
cord-264532-xfb94lq8	160	17	distinguish	distinguish	VB
cord-264532-xfb94lq8	160	18	,	,	,
cord-264532-xfb94lq8	160	19	as	as	IN
cord-264532-xfb94lq8	160	20	either	either	DT
cord-264532-xfb94lq8	160	21	or	or	CC
cord-264532-xfb94lq8	160	22	both	both	DT
cord-264532-xfb94lq8	160	23	could	could	MD
cord-264532-xfb94lq8	160	24	obtain	obtain	VB
cord-264532-xfb94lq8	160	25	across	across	IN
cord-264532-xfb94lq8	160	26	repeated	repeat	VBN
cord-264532-xfb94lq8	160	27	invasions	invasion	NNS
cord-264532-xfb94lq8	160	28	.	.	.
cord-264532-xfb94lq8	161	1	However	however	RB
cord-264532-xfb94lq8	161	2	,	,	,
cord-264532-xfb94lq8	161	3	observing	observe	VBG
cord-264532-xfb94lq8	161	4	the	the	DT
cord-264532-xfb94lq8	161	5	evolution	evolution	NN
cord-264532-xfb94lq8	161	6	of	of	IN
cord-264532-xfb94lq8	161	7	an	an	DT
cord-264532-xfb94lq8	161	8	increase	increase	NN
cord-264532-xfb94lq8	161	9	in	in	IN
cord-264532-xfb94lq8	161	10	virulence	virulence	NN
cord-264532-xfb94lq8	161	11	(	(	-LRB-
cord-264532-xfb94lq8	161	12	instead	instead	RB
cord-264532-xfb94lq8	161	13	of	of	IN
cord-264532-xfb94lq8	161	14	a	a	DT
cord-264532-xfb94lq8	161	15	decrease	decrease	NN
cord-264532-xfb94lq8	161	16	)	)	-RRB-
cord-264532-xfb94lq8	161	17	as	as	IN
cord-264532-xfb94lq8	161	18	the	the	DT
cord-264532-xfb94lq8	161	19	epidemic	epidemic	NN
cord-264532-xfb94lq8	161	20	matures	mature	VBZ
cord-264532-xfb94lq8	161	21	would	would	MD
cord-264532-xfb94lq8	161	22	support	support	VB
cord-264532-xfb94lq8	161	23	the	the	DT
cord-264532-xfb94lq8	161	24	invasion	invasion	NN
cord-264532-xfb94lq8	161	25	threshold	threshold	NN
cord-264532-xfb94lq8	161	26	model	model	NN
cord-264532-xfb94lq8	161	27	for	for	IN
cord-264532-xfb94lq8	161	28	the	the	DT
cord-264532-xfb94lq8	161	29	initial	initial	JJ
cord-264532-xfb94lq8	161	30	virulence	virulence	NN
cord-264532-xfb94lq8	161	31	,	,	,
cord-264532-xfb94lq8	161	32	because	because	IN
cord-264532-xfb94lq8	161	33	the	the	DT
cord-264532-xfb94lq8	161	34	Lenski	Lenski	NNP
cord-264532-xfb94lq8	161	35	-	-	HYPH
cord-264532-xfb94lq8	161	36	May	May	NNP
cord-264532-xfb94lq8	161	37	optima	optima	NNP
cord-264532-xfb94lq8	161	38	shift	shift	NN
cord-264532-xfb94lq8	161	39	toward	toward	IN
cord-264532-xfb94lq8	161	40	decreasing	decrease	VBG
cord-264532-xfb94lq8	161	41	virulence	virulence	NN
cord-264532-xfb94lq8	161	42	as	as	IN
cord-264532-xfb94lq8	161	43	the	the	DT
cord-264532-xfb94lq8	161	44	epidemic	epidemic	NN
cord-264532-xfb94lq8	161	45	matures	mature	VBZ
cord-264532-xfb94lq8	161	46	.	.	.
cord-264532-xfb94lq8	162	1	Likewise	likewise	RB
cord-264532-xfb94lq8	162	2	,	,	,
cord-264532-xfb94lq8	162	3	if	if	IN
cord-264532-xfb94lq8	162	4	hosts	host	NNS
cord-264532-xfb94lq8	162	5	merely	merely	RB
cord-264532-xfb94lq8	162	6	die	die	VBP
cord-264532-xfb94lq8	162	7	from	from	IN
cord-264532-xfb94lq8	162	8	the	the	DT
cord-264532-xfb94lq8	162	9	infection	infection	NN
cord-264532-xfb94lq8	162	10	and	and	CC
cord-264532-xfb94lq8	162	11	do	do	VBP
cord-264532-xfb94lq8	162	12	not	not	RB
cord-264532-xfb94lq8	162	13	recover	recover	VB
cord-264532-xfb94lq8	162	14	(	(	-LRB-
cord-264532-xfb94lq8	162	15	and	and	CC
cord-264532-xfb94lq8	162	16	are	be	VBP
cord-264532-xfb94lq8	162	17	not	not	RB
cord-264532-xfb94lq8	162	18	resistant	resistant	JJ
cord-264532-xfb94lq8	162	19	)	)	-RRB-
cord-264532-xfb94lq8	162	20	,	,	,
cord-264532-xfb94lq8	162	21	then	then	RB
cord-264532-xfb94lq8	162	22	the	the	DT
cord-264532-xfb94lq8	162	23	invasion	invasion	NN
cord-264532-xfb94lq8	162	24	threshold	threshold	NN
cord-264532-xfb94lq8	162	25	model	model	NN
cord-264532-xfb94lq8	162	26	can	can	MD
cord-264532-xfb94lq8	162	27	not	not	RB
cord-264532-xfb94lq8	162	28	possibly	possibly	RB
cord-264532-xfb94lq8	162	29	apply	apply	VB
cord-264532-xfb94lq8	162	30	after	after	IN
cord-264532-xfb94lq8	162	31	dynamical	dynamical	JJ
cord-264532-xfb94lq8	162	32	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	162	33	has	have	VBZ
cord-264532-xfb94lq8	162	34	been	be	VBN
cord-264532-xfb94lq8	162	35	reached	reach	VBN
cord-264532-xfb94lq8	162	36	,	,	,
cord-264532-xfb94lq8	162	37	because	because	IN
cord-264532-xfb94lq8	162	38	there	there	EX
cord-264532-xfb94lq8	162	39	is	be	VBZ
cord-264532-xfb94lq8	162	40	no	no	DT
cord-264532-xfb94lq8	162	41	reservoir	reservoir	NN
cord-264532-xfb94lq8	162	42	of	of	IN
cord-264532-xfb94lq8	162	43	immune	immune	JJ
cord-264532-xfb94lq8	162	44	or	or	CC
cord-264532-xfb94lq8	162	45	resistant	resistant	JJ
cord-264532-xfb94lq8	162	46	hosts	host	NNS
cord-264532-xfb94lq8	162	47	to	to	TO
cord-264532-xfb94lq8	162	48	be	be	VB
cord-264532-xfb94lq8	162	49	exploited	exploit	VBN
cord-264532-xfb94lq8	162	50	by	by	IN
cord-264532-xfb94lq8	162	51	a	a	DT
cord-264532-xfb94lq8	162	52	mutant	mutant	JJ
cord-264532-xfb94lq8	162	53	parasite	parasite	NN
cord-264532-xfb94lq8	162	54	.	.	.
cord-264532-xfb94lq8	163	1	For	for	IN
cord-264532-xfb94lq8	163	2	many	many	JJ
cord-264532-xfb94lq8	163	3	parasites	parasite	NNS
cord-264532-xfb94lq8	163	4	,	,	,
cord-264532-xfb94lq8	163	5	evolvability	evolvability	NN
cord-264532-xfb94lq8	163	6	to	to	TO
cord-264532-xfb94lq8	163	7	escape	escape	VB
cord-264532-xfb94lq8	163	8	existing	exist	VBG
cord-264532-xfb94lq8	163	9	immune	immune	NN
cord-264532-xfb94lq8	163	10	and	and	CC
cord-264532-xfb94lq8	163	11	resistance	resistance	NN
cord-264532-xfb94lq8	163	12	profiles	profile	NNS
cord-264532-xfb94lq8	163	13	is	be	VBZ
cord-264532-xfb94lq8	163	14	highly	highly	RB
cord-264532-xfb94lq8	163	15	adaptive	adaptive	JJ
cord-264532-xfb94lq8	163	16	.	.	.
cord-264532-xfb94lq8	164	1	Longterm	longterm	JJ
cord-264532-xfb94lq8	164	2	parasite	parasite	NN
cord-264532-xfb94lq8	164	3	success	success	NN
cord-264532-xfb94lq8	164	4	may	may	MD
cord-264532-xfb94lq8	164	5	depend	depend	VB
cord-264532-xfb94lq8	164	6	not	not	RB
cord-264532-xfb94lq8	164	7	so	so	RB
cord-264532-xfb94lq8	164	8	much	much	JJ
cord-264532-xfb94lq8	164	9	on	on	IN
cord-264532-xfb94lq8	164	10	the	the	DT
cord-264532-xfb94lq8	164	11	ability	ability	NN
cord-264532-xfb94lq8	164	12	to	to	TO
cord-264532-xfb94lq8	164	13	achieve	achieve	VB
cord-264532-xfb94lq8	164	14	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	164	15	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	164	16	,	,	,
cord-264532-xfb94lq8	164	17	as	as	IN
cord-264532-xfb94lq8	164	18	in	in	IN
cord-264532-xfb94lq8	164	19	the	the	DT
cord-264532-xfb94lq8	164	20	classic	classic	JJ
cord-264532-xfb94lq8	164	21	virulence	virulence	NN
cord-264532-xfb94lq8	164	22	evolution	evolution	NN
cord-264532-xfb94lq8	164	23	models	model	NNS
cord-264532-xfb94lq8	164	24	,	,	,
cord-264532-xfb94lq8	164	25	but	but	CC
cord-264532-xfb94lq8	164	26	rather	rather	RB
cord-264532-xfb94lq8	164	27	to	to	TO
cord-264532-xfb94lq8	164	28	keep	keep	VB
cord-264532-xfb94lq8	164	29	changing	change	VBG
cord-264532-xfb94lq8	164	30	,	,	,
cord-264532-xfb94lq8	164	31	staying	stay	VBG
cord-264532-xfb94lq8	164	32	ahead	ahead	RB
cord-264532-xfb94lq8	164	33	of	of	IN
cord-264532-xfb94lq8	164	34	host	host	NN
cord-264532-xfb94lq8	164	35	defenses	defense	NNS
cord-264532-xfb94lq8	164	36	and	and	CC
cord-264532-xfb94lq8	164	37	continually	continually	RB
cord-264532-xfb94lq8	164	38	jumping	jump	VBG
cord-264532-xfb94lq8	164	39	outside	outside	IN
cord-264532-xfb94lq8	164	40	the	the	DT
cord-264532-xfb94lq8	164	41	parameter	parameter	NN
cord-264532-xfb94lq8	164	42	space	space	NN
cord-264532-xfb94lq8	164	43	confining	confine	VBG
cord-264532-xfb94lq8	164	44	the	the	DT
cord-264532-xfb94lq8	164	45	parasite	parasite	NN
cord-264532-xfb94lq8	164	46	's	's	POS
cord-264532-xfb94lq8	164	47	recent	recent	JJ
cord-264532-xfb94lq8	164	48	ancestors	ancestor	NNS
cord-264532-xfb94lq8	164	49	.	.	.
cord-264532-xfb94lq8	165	1	Such	such	PDT
cord-264532-xfb94lq8	165	2	a	a	DT
cord-264532-xfb94lq8	165	3	process	process	NN
cord-264532-xfb94lq8	165	4	would	would	MD
cord-264532-xfb94lq8	165	5	ensure	ensure	VB
cord-264532-xfb94lq8	165	6	that	that	IN
cord-264532-xfb94lq8	165	7	the	the	DT
cord-264532-xfb94lq8	165	8	invasion	invasion	NN
cord-264532-xfb94lq8	165	9	threshold	threshold	NN
cord-264532-xfb94lq8	165	10	model	model	NN
cord-264532-xfb94lq8	165	11	is	be	VBZ
cord-264532-xfb94lq8	165	12	relevant	relevant	JJ
cord-264532-xfb94lq8	165	13	at	at	IN
cord-264532-xfb94lq8	165	14	many	many	JJ
cord-264532-xfb94lq8	165	15	episodes	episode	NNS
cord-264532-xfb94lq8	165	16	in	in	IN
cord-264532-xfb94lq8	165	17	the	the	DT
cord-264532-xfb94lq8	165	18	parasite	parasite	NN
cord-264532-xfb94lq8	165	19	's	's	POS
cord-264532-xfb94lq8	165	20	history	history	NN
cord-264532-xfb94lq8	165	21	.	.	.
cord-264532-xfb94lq8	166	1	The	the	DT
cord-264532-xfb94lq8	166	2	applicability	applicability	NN
cord-264532-xfb94lq8	166	3	of	of	IN
cord-264532-xfb94lq8	166	4	the	the	DT
cord-264532-xfb94lq8	166	5	invasion	invasion	NN
cord-264532-xfb94lq8	166	6	threshold	threshold	NN
cord-264532-xfb94lq8	166	7	model	model	NN
cord-264532-xfb94lq8	166	8	at	at	IN
cord-264532-xfb94lq8	166	9	some	some	DT
cord-264532-xfb94lq8	166	10	times	time	NNS
cord-264532-xfb94lq8	166	11	does	do	VBZ
cord-264532-xfb94lq8	166	12	not	not	RB
cord-264532-xfb94lq8	166	13	exclude	exclude	VB
cord-264532-xfb94lq8	166	14	attainment	attainment	JJ
cord-264532-xfb94lq8	166	15	of	of	IN
cord-264532-xfb94lq8	166	16	optima	optima	NNP
cord-264532-xfb94lq8	166	17	at	at	IN
cord-264532-xfb94lq8	166	18	other	other	JJ
cord-264532-xfb94lq8	166	19	times	time	NNS
cord-264532-xfb94lq8	166	20	.	.	.
cord-264532-xfb94lq8	167	1	Thus	thus	RB
cord-264532-xfb94lq8	167	2	,	,	,
cord-264532-xfb94lq8	167	3	over	over	IN
cord-264532-xfb94lq8	167	4	the	the	DT
cord-264532-xfb94lq8	167	5	course	course	NN
cord-264532-xfb94lq8	167	6	of	of	IN
cord-264532-xfb94lq8	167	7	history	history	NN
cord-264532-xfb94lq8	167	8	,	,	,
cord-264532-xfb94lq8	167	9	there	there	EX
cord-264532-xfb94lq8	167	10	can	can	MD
cord-264532-xfb94lq8	167	11	be	be	VB
cord-264532-xfb94lq8	167	12	a	a	DT
cord-264532-xfb94lq8	167	13	cycling	cycling	NN
cord-264532-xfb94lq8	167	14	between	between	IN
cord-264532-xfb94lq8	167	15	invasion	invasion	NN
cord-264532-xfb94lq8	167	16	,	,	,
cord-264532-xfb94lq8	167	17	evolution	evolution	NN
cord-264532-xfb94lq8	167	18	toward	toward	IN
cord-264532-xfb94lq8	167	19	an	an	DT
cord-264532-xfb94lq8	167	20	optimum	optimum	NN
cord-264532-xfb94lq8	167	21	(	(	-LRB-
cord-264532-xfb94lq8	167	22	perhaps	perhaps	RB
cord-264532-xfb94lq8	167	23	indirectly	indirectly	RB
cord-264532-xfb94lq8	167	24	)	)	-RRB-
cord-264532-xfb94lq8	167	25	,	,	,
cord-264532-xfb94lq8	167	26	and	and	CC
cord-264532-xfb94lq8	167	27	maintenance	maintenance	NN
cord-264532-xfb94lq8	167	28	of	of	IN
cord-264532-xfb94lq8	167	29	an	an	DT
cord-264532-xfb94lq8	167	30	optimal	optimal	JJ
cord-264532-xfb94lq8	167	31	state	state	NN
cord-264532-xfb94lq8	167	32	.	.	.
cord-264532-xfb94lq8	168	1	The	the	DT
cord-264532-xfb94lq8	168	2	relative	relative	JJ
cord-264532-xfb94lq8	168	3	importance	importance	NN
cord-264532-xfb94lq8	168	4	of	of	IN
cord-264532-xfb94lq8	168	5	Figure	figure	NN
cord-264532-xfb94lq8	168	6	4	4	CD
cord-264532-xfb94lq8	168	7	Indeterminacy	indeterminacy	NN
cord-264532-xfb94lq8	168	8	of	of	IN
cord-264532-xfb94lq8	168	9	virulence	virulence	NN
cord-264532-xfb94lq8	168	10	(	(	-LRB-
cord-264532-xfb94lq8	168	11	host	host	NN
cord-264532-xfb94lq8	168	12	mortality	mortality	NN
cord-264532-xfb94lq8	168	13	rate	rate	NN
cord-264532-xfb94lq8	168	14	)	)	-RRB-
cord-264532-xfb94lq8	169	1	when	when	WRB
cord-264532-xfb94lq8	169	2	hosts	host	NNS
cord-264532-xfb94lq8	169	3	recover	recover	VBP
cord-264532-xfb94lq8	169	4	and	and	CC
cord-264532-xfb94lq8	169	5	are	be	VBP
cord-264532-xfb94lq8	169	6	immune	immune	JJ
cord-264532-xfb94lq8	169	7	to	to	IN
cord-264532-xfb94lq8	169	8	subsequent	subsequent	JJ
cord-264532-xfb94lq8	169	9	infection	infection	NN
cord-264532-xfb94lq8	169	10	.	.	.
cord-264532-xfb94lq8	170	1	When	when	WRB
cord-264532-xfb94lq8	170	2	recovery	recovery	NN
cord-264532-xfb94lq8	170	3	is	be	VBZ
cord-264532-xfb94lq8	170	4	allowed	allow	VBN
cord-264532-xfb94lq8	170	5	as	as	IN
cord-264532-xfb94lq8	170	6	a	a	DT
cord-264532-xfb94lq8	170	7	component	component	NN
cord-264532-xfb94lq8	170	8	of	of	IN
cord-264532-xfb94lq8	170	9	d	d	NN
cord-264532-xfb94lq8	170	10	in	in	IN
cord-264532-xfb94lq8	170	11	equation	equation	NN
cord-264532-xfb94lq8	170	12	(	(	-LRB-
cord-264532-xfb94lq8	170	13	1	1	CD
cord-264532-xfb94lq8	170	14	)	)	-RRB-
cord-264532-xfb94lq8	170	15	,	,	,
cord-264532-xfb94lq8	170	16	such	such	JJ
cord-264532-xfb94lq8	170	17	that	that	IN
cord-264532-xfb94lq8	170	18	d¢	d¢	NN
cord-264532-xfb94lq8	171	1	=	=	NFP
cord-264532-xfb94lq8	171	2	d	d	NNP
cord-264532-xfb94lq8	172	1	+	+	CC
cord-264532-xfb94lq8	172	2	q	q	NNP
cord-264532-xfb94lq8	172	3	is	be	VBZ
cord-264532-xfb94lq8	172	4	substituted	substitute	VBN
cord-264532-xfb94lq8	172	5	for	for	IN
cord-264532-xfb94lq8	172	6	d	d	NNP
cord-264532-xfb94lq8	172	7	,	,	,
cord-264532-xfb94lq8	172	8	the	the	DT
cord-264532-xfb94lq8	172	9	evolution	evolution	NN
cord-264532-xfb94lq8	172	10	of	of	IN
cord-264532-xfb94lq8	172	11	higher	high	JJR
cord-264532-xfb94lq8	172	12	d¢	d¢	NN
cord-264532-xfb94lq8	172	13	no	no	RB
cord-264532-xfb94lq8	172	14	longer	long	RBR
cord-264532-xfb94lq8	172	15	implies	imply	VBZ
cord-264532-xfb94lq8	172	16	the	the	DT
cord-264532-xfb94lq8	172	17	evolution	evolution	NN
cord-264532-xfb94lq8	172	18	of	of	IN
cord-264532-xfb94lq8	172	19	higher	high	JJR
cord-264532-xfb94lq8	172	20	virulence	virulence	NN
cord-264532-xfb94lq8	172	21	.	.	.
cord-264532-xfb94lq8	173	1	The	the	DT
cord-264532-xfb94lq8	173	2	trade	trade	NN
cord-264532-xfb94lq8	173	3	-	-	HYPH
cord-264532-xfb94lq8	173	4	off	off	RP
cord-264532-xfb94lq8	173	5	boundary	boundary	NN
cord-264532-xfb94lq8	173	6	(	(	-LRB-
cord-264532-xfb94lq8	173	7	between	between	IN
cord-264532-xfb94lq8	173	8	d¢	d¢	NN
cord-264532-xfb94lq8	173	9	and	and	CC
cord-264532-xfb94lq8	173	10	transmission	transmission	NN
cord-264532-xfb94lq8	173	11	)	)	-RRB-
cord-264532-xfb94lq8	173	12	is	be	VBZ
cord-264532-xfb94lq8	173	13	given	give	VBN
cord-264532-xfb94lq8	173	14	by	by	IN
cord-264532-xfb94lq8	173	15	the	the	DT
cord-264532-xfb94lq8	173	16	black	black	JJ
cord-264532-xfb94lq8	173	17	line	line	NN
cord-264532-xfb94lq8	173	18	at	at	IN
cord-264532-xfb94lq8	173	19	the	the	DT
cord-264532-xfb94lq8	173	20	upper	upper	JJ
cord-264532-xfb94lq8	173	21	boundary	boundary	NN
cord-264532-xfb94lq8	173	22	of	of	IN
cord-264532-xfb94lq8	173	23	the	the	DT
cord-264532-xfb94lq8	173	24	gray	gray	JJ
cord-264532-xfb94lq8	173	25	area	area	NN
cord-264532-xfb94lq8	173	26	,	,	,
cord-264532-xfb94lq8	173	27	and	and	CC
cord-264532-xfb94lq8	173	28	it	-PRON-	PRP
cord-264532-xfb94lq8	173	29	can	can	MD
cord-264532-xfb94lq8	173	30	be	be	VB
cord-264532-xfb94lq8	173	31	seen	see	VBN
cord-264532-xfb94lq8	173	32	in	in	IN
cord-264532-xfb94lq8	173	33	the	the	DT
cord-264532-xfb94lq8	173	34	shift	shift	NN
cord-264532-xfb94lq8	173	35	from	from	IN
cord-264532-xfb94lq8	173	36	left	leave	VBN
cord-264532-xfb94lq8	173	37	to	to	IN
cord-264532-xfb94lq8	173	38	right	right	JJ
cord-264532-xfb94lq8	173	39	graphs	graph	NNS
cord-264532-xfb94lq8	173	40	that	that	IN
cord-264532-xfb94lq8	173	41	d¢	d¢	NN
cord-264532-xfb94lq8	173	42	increases	increase	VBZ
cord-264532-xfb94lq8	173	43	somewhat	somewhat	RB
cord-264532-xfb94lq8	173	44	but	but	CC
cord-264532-xfb94lq8	173	45	host	host	NN
cord-264532-xfb94lq8	173	46	mortality	mortality	NN
cord-264532-xfb94lq8	173	47	rate	rate	NN
cord-264532-xfb94lq8	173	48	decreases	decrease	NNS
cord-264532-xfb94lq8	173	49	.	.	.
cord-264532-xfb94lq8	174	1	The	the	DT
cord-264532-xfb94lq8	174	2	sizes	size	NNS
cord-264532-xfb94lq8	174	3	of	of	IN
cord-264532-xfb94lq8	174	4	the	the	DT
cord-264532-xfb94lq8	174	5	gray	gray	JJ
cord-264532-xfb94lq8	174	6	and	and	CC
cord-264532-xfb94lq8	174	7	clear	clear	JJ
cord-264532-xfb94lq8	174	8	areas	area	NNS
cord-264532-xfb94lq8	174	9	are	be	VBP
cord-264532-xfb94lq8	174	10	drawn	draw	VBN
cord-264532-xfb94lq8	174	11	for	for	IN
cord-264532-xfb94lq8	174	12	illustration	illustration	NN
cord-264532-xfb94lq8	174	13	and	and	CC
cord-264532-xfb94lq8	174	14	are	be	VBP
cord-264532-xfb94lq8	174	15	not	not	RB
cord-264532-xfb94lq8	174	16	based	base	VBN
cord-264532-xfb94lq8	174	17	on	on	IN
cord-264532-xfb94lq8	174	18	data	datum	NNS
cord-264532-xfb94lq8	174	19	.	.	.
cord-264532-xfb94lq8	175	1	each	each	DT
cord-264532-xfb94lq8	175	2	phase	phase	NN
cord-264532-xfb94lq8	175	3	will	will	MD
cord-264532-xfb94lq8	175	4	depend	depend	VB
cord-264532-xfb94lq8	175	5	on	on	IN
cord-264532-xfb94lq8	175	6	details	detail	NNS
cord-264532-xfb94lq8	175	7	of	of	IN
cord-264532-xfb94lq8	175	8	the	the	DT
cord-264532-xfb94lq8	175	9	parasite	parasite	NN
cord-264532-xfb94lq8	175	10	and	and	CC
cord-264532-xfb94lq8	175	11	host	host	NN
cord-264532-xfb94lq8	175	12	.	.	.
cord-264532-xfb94lq8	176	1	We	-PRON-	PRP
cord-264532-xfb94lq8	176	2	offer	offer	VBP
cord-264532-xfb94lq8	176	3	the	the	DT
cord-264532-xfb94lq8	176	4	caveat	caveat	NN
cord-264532-xfb94lq8	176	5	that	that	IN
cord-264532-xfb94lq8	176	6	the	the	DT
cord-264532-xfb94lq8	176	7	invasion	invasion	NN
cord-264532-xfb94lq8	176	8	threshold	threshold	NN
cord-264532-xfb94lq8	176	9	model	model	NN
cord-264532-xfb94lq8	176	10	is	be	VBZ
cord-264532-xfb94lq8	176	11	not	not	RB
cord-264532-xfb94lq8	176	12	the	the	DT
cord-264532-xfb94lq8	176	13	only	only	JJ
cord-264532-xfb94lq8	176	14	model	model	NN
cord-264532-xfb94lq8	176	15	for	for	IN
cord-264532-xfb94lq8	176	16	nonoptimal	nonoptimal	JJ
cord-264532-xfb94lq8	176	17	virulence	virulence	NN
cord-264532-xfb94lq8	176	18	(	(	-LRB-
cord-264532-xfb94lq8	176	19	Dieckmann	Dieckmann	NNP
cord-264532-xfb94lq8	176	20	2002	2002	CD
cord-264532-xfb94lq8	176	21	)	)	-RRB-
cord-264532-xfb94lq8	176	22	.	.	.
cord-264532-xfb94lq8	177	1	If	if	IN
cord-264532-xfb94lq8	177	2	host	host	NN
cord-264532-xfb94lq8	177	3	and	and	CC
cord-264532-xfb94lq8	177	4	parasite	parasite	NN
cord-264532-xfb94lq8	177	5	populations	population	NNS
cord-264532-xfb94lq8	177	6	cycle	cycle	NN
cord-264532-xfb94lq8	177	7	,	,	,
cord-264532-xfb94lq8	177	8	or	or	CC
cord-264532-xfb94lq8	177	9	if	if	IN
cord-264532-xfb94lq8	177	10	environmental	environmental	JJ
cord-264532-xfb94lq8	177	11	factors	factor	NNS
cord-264532-xfb94lq8	177	12	cause	cause	VBP
cord-264532-xfb94lq8	177	13	host	host	NN
cord-264532-xfb94lq8	177	14	populations	population	NNS
cord-264532-xfb94lq8	177	15	to	to	TO
cord-264532-xfb94lq8	177	16	fluctuate	fluctuate	VB
cord-264532-xfb94lq8	177	17	profoundly	profoundly	RB
cord-264532-xfb94lq8	177	18	,	,	,
cord-264532-xfb94lq8	177	19	there	there	EX
cord-264532-xfb94lq8	177	20	will	will	MD
cord-264532-xfb94lq8	177	21	be	be	VB
cord-264532-xfb94lq8	177	22	no	no	DT
cord-264532-xfb94lq8	177	23	single	single	JJ
cord-264532-xfb94lq8	177	24	virulence	virulence	NN
cord-264532-xfb94lq8	177	25	optimum	optimum	JJ
cord-264532-xfb94lq8	177	26	,	,	,
cord-264532-xfb94lq8	177	27	and	and	CC
cord-264532-xfb94lq8	177	28	the	the	DT
cord-264532-xfb94lq8	177	29	best	good	JJS
cord-264532-xfb94lq8	177	30	the	the	DT
cord-264532-xfb94lq8	177	31	parasite	parasite	NN
cord-264532-xfb94lq8	177	32	might	may	MD
cord-264532-xfb94lq8	177	33	do	do	VB
cord-264532-xfb94lq8	177	34	is	be	VBZ
cord-264532-xfb94lq8	177	35	to	to	TO
cord-264532-xfb94lq8	177	36	track	track	VB
cord-264532-xfb94lq8	177	37	a	a	DT
cord-264532-xfb94lq8	177	38	moving	move	VBG
cord-264532-xfb94lq8	177	39	optimum	optimum	JJ
cord-264532-xfb94lq8	177	40	Gandon	Gandon	NNP
cord-264532-xfb94lq8	177	41	2006	2006	CD
cord-264532-xfb94lq8	177	42	,	,	,
cord-264532-xfb94lq8	177	43	2007	2007	CD
cord-264532-xfb94lq8	177	44	]	]	-RRB-
cord-264532-xfb94lq8	177	45	.	.	.
cord-264532-xfb94lq8	178	1	Likewise	likewise	RB
cord-264532-xfb94lq8	178	2	,	,	,
cord-264532-xfb94lq8	178	3	if	if	IN
cord-264532-xfb94lq8	178	4	hosts	host	NNS
cord-264532-xfb94lq8	178	5	are	be	VBP
cord-264532-xfb94lq8	178	6	infected	infect	VBN
cord-264532-xfb94lq8	178	7	by	by	IN
cord-264532-xfb94lq8	178	8	multiple	multiple	JJ
cord-264532-xfb94lq8	178	9	strains	strain	NNS
cord-264532-xfb94lq8	178	10	of	of	IN
cord-264532-xfb94lq8	178	11	parasites	parasite	NNS
cord-264532-xfb94lq8	178	12	,	,	,
cord-264532-xfb94lq8	178	13	parasite	parasite	NN
cord-264532-xfb94lq8	178	14	-	-	HYPH
cord-264532-xfb94lq8	178	15	parasite	parasite	NN
cord-264532-xfb94lq8	178	16	competition	competition	NN
cord-264532-xfb94lq8	178	17	within	within	IN
cord-264532-xfb94lq8	178	18	hosts	host	NNS
cord-264532-xfb94lq8	178	19	will	will	MD
cord-264532-xfb94lq8	178	20	often	often	RB
cord-264532-xfb94lq8	178	21	lead	lead	VB
cord-264532-xfb94lq8	178	22	to	to	IN
cord-264532-xfb94lq8	178	23	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	178	24	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	178	25	dynamics	dynamic	NNS
cord-264532-xfb94lq8	178	26	(	(	-LRB-
cord-264532-xfb94lq8	178	27	Frank	Frank	NNP
cord-264532-xfb94lq8	178	28	1996	1996	CD
cord-264532-xfb94lq8	178	29	;	;	:
cord-264532-xfb94lq8	178	30	Bull	Bull	NNP
cord-264532-xfb94lq8	178	31	et	et	NNP
cord-264532-xfb94lq8	178	32	al	al	NNP
cord-264532-xfb94lq8	178	33	.	.	.
cord-264532-xfb94lq8	178	34	2006	2006	CD
cord-264532-xfb94lq8	178	35	)	)	-RRB-
cord-264532-xfb94lq8	178	36	.	.	.
cord-264532-xfb94lq8	179	1	It	-PRON-	PRP
cord-264532-xfb94lq8	179	2	should	should	MD
cord-264532-xfb94lq8	179	3	also	also	RB
cord-264532-xfb94lq8	179	4	be	be	VB
cord-264532-xfb94lq8	179	5	noted	note	VBN
cord-264532-xfb94lq8	179	6	that	that	IN
cord-264532-xfb94lq8	179	7	different	different	JJ
cord-264532-xfb94lq8	179	8	mathematical	mathematical	JJ
cord-264532-xfb94lq8	179	9	definitions	definition	NNS
cord-264532-xfb94lq8	179	10	of	of	IN
cord-264532-xfb94lq8	179	11	virulence	virulence	NN
cord-264532-xfb94lq8	179	12	have	have	VBP
cord-264532-xfb94lq8	179	13	different	different	JJ
cord-264532-xfb94lq8	179	14	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	179	15	consequences	consequence	NNS
cord-264532-xfb94lq8	179	16	(	(	-LRB-
cord-264532-xfb94lq8	179	17	Day	Day	NNP
cord-264532-xfb94lq8	179	18	2002	2002	CD
cord-264532-xfb94lq8	179	19	)	)	-RRB-
cord-264532-xfb94lq8	179	20	,	,	,
cord-264532-xfb94lq8	179	21	but	but	CC
cord-264532-xfb94lq8	179	22	again	again	RB
cord-264532-xfb94lq8	179	23	,	,	,
cord-264532-xfb94lq8	179	24	our	-PRON-	PRP$
cord-264532-xfb94lq8	179	25	point	point	NN
cord-264532-xfb94lq8	179	26	about	about	IN
cord-264532-xfb94lq8	179	27	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	179	28	dynamics	dynamic	NNS
cord-264532-xfb94lq8	179	29	should	should	MD
cord-264532-xfb94lq8	179	30	hold	hold	VB
cord-264532-xfb94lq8	179	31	under	under	IN
cord-264532-xfb94lq8	179	32	many	many	JJ
cord-264532-xfb94lq8	179	33	of	of	IN
cord-264532-xfb94lq8	179	34	those	those	DT
cord-264532-xfb94lq8	179	35	alternatives	alternative	NNS
cord-264532-xfb94lq8	179	36	.	.	.
cord-264532-xfb94lq8	180	1	The	the	DT
cord-264532-xfb94lq8	180	2	general	general	JJ
cord-264532-xfb94lq8	180	3	point	point	NN
cord-264532-xfb94lq8	180	4	of	of	IN
cord-264532-xfb94lq8	180	5	the	the	DT
cord-264532-xfb94lq8	180	6	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	180	7	model	model	NN
cord-264532-xfb94lq8	180	8	is	be	VBZ
cord-264532-xfb94lq8	180	9	that	that	IN
cord-264532-xfb94lq8	180	10	optimality	optimality	NN
cord-264532-xfb94lq8	180	11	of	of	IN
cord-264532-xfb94lq8	180	12	a	a	DT
cord-264532-xfb94lq8	180	13	phenotype	phenotype	NN
cord-264532-xfb94lq8	180	14	involved	involve	VBN
cord-264532-xfb94lq8	180	15	in	in	IN
cord-264532-xfb94lq8	180	16	a	a	DT
cord-264532-xfb94lq8	180	17	trade	trade	NN
cord-264532-xfb94lq8	180	18	-	-	HYPH
cord-264532-xfb94lq8	180	19	off	off	NN
cord-264532-xfb94lq8	180	20	may	may	MD
cord-264532-xfb94lq8	180	21	be	be	VB
cord-264532-xfb94lq8	180	22	evolved	evolve	VBN
cord-264532-xfb94lq8	180	23	only	only	RB
cord-264532-xfb94lq8	180	24	slowly	slowly	RB
cord-264532-xfb94lq8	180	25	;	;	:
cord-264532-xfb94lq8	180	26	our	-PRON-	PRP$
cord-264532-xfb94lq8	180	27	specific	specific	JJ
cord-264532-xfb94lq8	180	28	context	context	NN
cord-264532-xfb94lq8	180	29	is	be	VBZ
cord-264532-xfb94lq8	180	30	virulence	virulence	NN
cord-264532-xfb94lq8	180	31	.	.	.
cord-264532-xfb94lq8	181	1	There	there	EX
cord-264532-xfb94lq8	181	2	is	be	VBZ
cord-264532-xfb94lq8	181	3	no	no	DT
cord-264532-xfb94lq8	181	4	absolute	absolute	JJ
cord-264532-xfb94lq8	181	5	threshold	threshold	NN
cord-264532-xfb94lq8	181	6	for	for	IN
cord-264532-xfb94lq8	181	7	rejection	rejection	NN
cord-264532-xfb94lq8	181	8	of	of	IN
cord-264532-xfb94lq8	181	9	this	this	DT
cord-264532-xfb94lq8	181	10	model	model	NN
cord-264532-xfb94lq8	181	11	,	,	,
cord-264532-xfb94lq8	181	12	only	only	RB
cord-264532-xfb94lq8	181	13	a	a	DT
cord-264532-xfb94lq8	181	14	subjective	subjective	JJ
cord-264532-xfb94lq8	181	15	one	one	CD
cord-264532-xfb94lq8	181	16	of	of	IN
cord-264532-xfb94lq8	181	17	whether	whether	IN
cord-264532-xfb94lq8	181	18	evolution	evolution	NN
cord-264532-xfb94lq8	181	19	to	to	IN
cord-264532-xfb94lq8	181	20	the	the	DT
cord-264532-xfb94lq8	181	21	optimum	optimum	NN
cord-264532-xfb94lq8	181	22	is	be	VBZ
cord-264532-xfb94lq8	181	23	fast	fast	JJ
cord-264532-xfb94lq8	181	24	enough	enough	RB
cord-264532-xfb94lq8	181	25	that	that	IN
cord-264532-xfb94lq8	181	26	the	the	DT
cord-264532-xfb94lq8	181	27	period	period	NN
cord-264532-xfb94lq8	181	28	of	of	IN
cord-264532-xfb94lq8	181	29	meaningful	meaningful	JJ
cord-264532-xfb94lq8	181	30	deviation	deviation	NN
cord-264532-xfb94lq8	181	31	can	can	MD
cord-264532-xfb94lq8	181	32	be	be	VB
cord-264532-xfb94lq8	181	33	neglected	neglect	VBN
cord-264532-xfb94lq8	181	34	.	.	.
cord-264532-xfb94lq8	182	1	A	a	DT
cord-264532-xfb94lq8	182	2	quantification	quantification	NN
cord-264532-xfb94lq8	182	3	of	of	IN
cord-264532-xfb94lq8	182	4	nonoptimality	nonoptimality	NN
cord-264532-xfb94lq8	182	5	could	could	MD
cord-264532-xfb94lq8	182	6	be	be	VB
cord-264532-xfb94lq8	182	7	provided	provide	VBN
cord-264532-xfb94lq8	182	8	by	by	IN
cord-264532-xfb94lq8	182	9	the	the	DT
cord-264532-xfb94lq8	182	10	experimental	experimental	JJ
cord-264532-xfb94lq8	182	11	adaptation	adaptation	NN
cord-264532-xfb94lq8	182	12	of	of	IN
cord-264532-xfb94lq8	182	13	a	a	DT
cord-264532-xfb94lq8	182	14	parasite	parasite	NN
cord-264532-xfb94lq8	182	15	with	with	IN
cord-264532-xfb94lq8	182	16	a	a	DT
cord-264532-xfb94lq8	182	17	known	know	VBN
cord-264532-xfb94lq8	182	18	optimum	optimum	NN
cord-264532-xfb94lq8	182	19	,	,	,
cord-264532-xfb94lq8	182	20	with	with	IN
cord-264532-xfb94lq8	182	21	the	the	DT
cord-264532-xfb94lq8	182	22	approach	approach	NN
cord-264532-xfb94lq8	182	23	to	to	IN
cord-264532-xfb94lq8	182	24	that	that	DT
cord-264532-xfb94lq8	182	25	optimum	optimum	NN
cord-264532-xfb94lq8	182	26	measured	measure	VBN
cord-264532-xfb94lq8	182	27	over	over	IN
cord-264532-xfb94lq8	182	28	time	time	NN
cord-264532-xfb94lq8	182	29	.	.	.
cord-264532-xfb94lq8	183	1	A	a	DT
cord-264532-xfb94lq8	183	2	test	test	NN
cord-264532-xfb94lq8	183	3	satisfying	satisfy	VBG
cord-264532-xfb94lq8	183	4	several	several	JJ
cord-264532-xfb94lq8	183	5	of	of	IN
cord-264532-xfb94lq8	183	6	these	these	DT
cord-264532-xfb94lq8	183	7	criteria	criterion	NNS
cord-264532-xfb94lq8	183	8	was	be	VBD
cord-264532-xfb94lq8	183	9	carried	carry	VBN
cord-264532-xfb94lq8	183	10	out	out	RP
cord-264532-xfb94lq8	183	11	for	for	IN
cord-264532-xfb94lq8	183	12	bacteriophage	bacteriophage	NN
cord-264532-xfb94lq8	183	13	lysis	lysis	NN
cord-264532-xfb94lq8	183	14	time	time	NN
cord-264532-xfb94lq8	183	15	,	,	,
cord-264532-xfb94lq8	183	16	analogous	analogous	JJ
cord-264532-xfb94lq8	183	17	to	to	IN
cord-264532-xfb94lq8	183	18	phage	phage	NN
cord-264532-xfb94lq8	183	19	virulence	virulence	NN
cord-264532-xfb94lq8	183	20	(	(	-LRB-
cord-264532-xfb94lq8	183	21	Heineman	Heineman	NNP
cord-264532-xfb94lq8	183	22	and	and	CC
cord-264532-xfb94lq8	183	23	Bull	Bull	NNP
cord-264532-xfb94lq8	183	24	2007	2007	CD
cord-264532-xfb94lq8	183	25	)	)	-RRB-
cord-264532-xfb94lq8	183	26	.	.	.
cord-264532-xfb94lq8	184	1	The	the	DT
cord-264532-xfb94lq8	184	2	optimum	optimum	NN
cord-264532-xfb94lq8	184	3	was	be	VBD
cord-264532-xfb94lq8	184	4	predicted	predict	VBN
cord-264532-xfb94lq8	184	5	when	when	WRB
cord-264532-xfb94lq8	184	6	assuming	assume	VBG
cord-264532-xfb94lq8	184	7	a	a	DT
cord-264532-xfb94lq8	184	8	linear	linear	JJ
cord-264532-xfb94lq8	184	9	trade	trade	NN
cord-264532-xfb94lq8	184	10	-	-	HYPH
cord-264532-xfb94lq8	184	11	off	off	NN
cord-264532-xfb94lq8	184	12	between	between	IN
cord-264532-xfb94lq8	184	13	lysis	lysis	NN
cord-264532-xfb94lq8	184	14	time	time	NN
cord-264532-xfb94lq8	184	15	and	and	CC
cord-264532-xfb94lq8	184	16	number	number	NN
cord-264532-xfb94lq8	184	17	of	of	IN
cord-264532-xfb94lq8	184	18	progeny	progeny	NN
cord-264532-xfb94lq8	184	19	at	at	IN
cord-264532-xfb94lq8	184	20	lysis	lysis	NN
cord-264532-xfb94lq8	184	21	and	and	CC
cord-264532-xfb94lq8	184	22	that	that	IN
cord-264532-xfb94lq8	184	23	the	the	DT
cord-264532-xfb94lq8	184	24	linearity	linearity	NN
cord-264532-xfb94lq8	184	25	extended	extend	VBN
cord-264532-xfb94lq8	184	26	well	well	RB
cord-264532-xfb94lq8	184	27	beyond	beyond	IN
cord-264532-xfb94lq8	184	28	the	the	DT
cord-264532-xfb94lq8	184	29	normal	normal	JJ
cord-264532-xfb94lq8	184	30	lysis	lysis	NN
cord-264532-xfb94lq8	184	31	time	time	NN
cord-264532-xfb94lq8	184	32	.	.	.
cord-264532-xfb94lq8	185	1	Adaptation	adaptation	NN
cord-264532-xfb94lq8	185	2	of	of	IN
cord-264532-xfb94lq8	185	3	phage	phage	NN
cord-264532-xfb94lq8	185	4	T7	T7	NNP
cord-264532-xfb94lq8	185	5	was	be	VBD
cord-264532-xfb94lq8	185	6	performed	perform	VBN
cord-264532-xfb94lq8	185	7	under	under	IN
cord-264532-xfb94lq8	185	8	constant	constant	JJ
cord-264532-xfb94lq8	185	9	environmental	environmental	JJ
cord-264532-xfb94lq8	185	10	conditions	condition	NNS
cord-264532-xfb94lq8	185	11	of	of	IN
cord-264532-xfb94lq8	185	12	both	both	CC
cord-264532-xfb94lq8	185	13	high	high	JJ
cord-264532-xfb94lq8	185	14	and	and	CC
cord-264532-xfb94lq8	185	15	low	low	JJ
cord-264532-xfb94lq8	185	16	host	host	NN
cord-264532-xfb94lq8	185	17	density	density	NN
cord-264532-xfb94lq8	185	18	;	;	:
cord-264532-xfb94lq8	185	19	this	this	DT
cord-264532-xfb94lq8	185	20	constant	constant	JJ
cord-264532-xfb94lq8	185	21	host	host	NN
cord-264532-xfb94lq8	185	22	density	density	NN
cord-264532-xfb94lq8	185	23	provided	provide	VBN
cord-264532-xfb94lq8	185	24	for	for	IN
cord-264532-xfb94lq8	185	25	a	a	DT
cord-264532-xfb94lq8	185	26	fixed	fixed	JJ
cord-264532-xfb94lq8	185	27	optimum	optimum	NN
cord-264532-xfb94lq8	185	28	and	and	CC
cord-264532-xfb94lq8	185	29	matches	match	VBZ
cord-264532-xfb94lq8	185	30	the	the	DT
cord-264532-xfb94lq8	185	31	models	model	NNS
cord-264532-xfb94lq8	185	32	in	in	IN
cord-264532-xfb94lq8	185	33	this	this	DT
cord-264532-xfb94lq8	185	34	paper	paper	NN
cord-264532-xfb94lq8	185	35	.	.	.
cord-264532-xfb94lq8	186	1	At	at	IN
cord-264532-xfb94lq8	186	2	high	high	JJ
cord-264532-xfb94lq8	186	3	host	host	NN
cord-264532-xfb94lq8	186	4	density	density	NN
cord-264532-xfb94lq8	186	5	,	,	,
cord-264532-xfb94lq8	186	6	T7	T7	NNP
cord-264532-xfb94lq8	186	7	attained	attain	VBD
cord-264532-xfb94lq8	186	8	a	a	DT
cord-264532-xfb94lq8	186	9	lysis	lysis	NN
cord-264532-xfb94lq8	186	10	time	time	NN
cord-264532-xfb94lq8	186	11	close	close	JJ
cord-264532-xfb94lq8	186	12	to	to	IN
cord-264532-xfb94lq8	186	13	the	the	DT
cord-264532-xfb94lq8	186	14	optimum	optimum	NN
cord-264532-xfb94lq8	186	15	within	within	IN
cord-264532-xfb94lq8	186	16	150	150	CD
cord-264532-xfb94lq8	186	17	generations	generation	NNS
cord-264532-xfb94lq8	186	18	of	of	IN
cord-264532-xfb94lq8	186	19	adaptation	adaptation	NN
cord-264532-xfb94lq8	186	20	,	,	,
cord-264532-xfb94lq8	186	21	but	but	CC
cord-264532-xfb94lq8	186	22	the	the	DT
cord-264532-xfb94lq8	186	23	phage	phage	NN
cord-264532-xfb94lq8	186	24	failed	fail	VBD
cord-264532-xfb94lq8	186	25	to	to	TO
cord-264532-xfb94lq8	186	26	approach	approach	VB
cord-264532-xfb94lq8	186	27	the	the	DT
cord-264532-xfb94lq8	186	28	optimum	optimum	NN
cord-264532-xfb94lq8	186	29	at	at	IN
cord-264532-xfb94lq8	186	30	low	low	JJ
cord-264532-xfb94lq8	186	31	host	host	NN
cord-264532-xfb94lq8	186	32	density	density	NN
cord-264532-xfb94lq8	186	33	in	in	IN
cord-264532-xfb94lq8	186	34	two	two	CD
cord-264532-xfb94lq8	186	35	separate	separate	JJ
cord-264532-xfb94lq8	186	36	adaptations	adaptation	NNS
cord-264532-xfb94lq8	186	37	of	of	IN
cord-264532-xfb94lq8	186	38	$	$	$
cord-264532-xfb94lq8	186	39	300	300	CD
cord-264532-xfb94lq8	186	40	generations	generation	NNS
cord-264532-xfb94lq8	186	41	each	each	DT
cord-264532-xfb94lq8	186	42	.	.	.
cord-264532-xfb94lq8	187	1	One	one	CD
cord-264532-xfb94lq8	187	2	failure	failure	NN
cord-264532-xfb94lq8	187	3	stemmed	stem	VBD
cord-264532-xfb94lq8	187	4	from	from	IN
cord-264532-xfb94lq8	187	5	a	a	DT
cord-264532-xfb94lq8	187	6	lack	lack	NN
cord-264532-xfb94lq8	187	7	of	of	IN
cord-264532-xfb94lq8	187	8	evolution	evolution	NN
cord-264532-xfb94lq8	187	9	,	,	,
cord-264532-xfb94lq8	187	10	likely	likely	JJ
cord-264532-xfb94lq8	187	11	because	because	IN
cord-264532-xfb94lq8	187	12	of	of	IN
cord-264532-xfb94lq8	187	13	small	small	JJ
cord-264532-xfb94lq8	187	14	population	population	NN
cord-264532-xfb94lq8	187	15	size	size	NN
cord-264532-xfb94lq8	187	16	.	.	.
cord-264532-xfb94lq8	188	1	In	in	IN
cord-264532-xfb94lq8	188	2	the	the	DT
cord-264532-xfb94lq8	188	3	other	other	JJ
cord-264532-xfb94lq8	188	4	case	case	NN
cord-264532-xfb94lq8	188	5	,	,	,
cord-264532-xfb94lq8	188	6	molecular	molecular	JJ
cord-264532-xfb94lq8	188	7	evolution	evolution	NN
cord-264532-xfb94lq8	188	8	was	be	VBD
cord-264532-xfb94lq8	188	9	observed	observe	VBN
cord-264532-xfb94lq8	188	10	,	,	,
cord-264532-xfb94lq8	188	11	and	and	CC
cord-264532-xfb94lq8	188	12	the	the	DT
cord-264532-xfb94lq8	188	13	failure	failure	NN
cord-264532-xfb94lq8	188	14	to	to	TO
cord-264532-xfb94lq8	188	15	attain	attain	VB
cord-264532-xfb94lq8	188	16	the	the	DT
cord-264532-xfb94lq8	188	17	optimum	optimum	NN
cord-264532-xfb94lq8	188	18	was	be	VBD
cord-264532-xfb94lq8	188	19	interpreted	interpret	VBN
cord-264532-xfb94lq8	188	20	as	as	IN
cord-264532-xfb94lq8	188	21	a	a	DT
cord-264532-xfb94lq8	188	22	failure	failure	NN
cord-264532-xfb94lq8	188	23	of	of	IN
cord-264532-xfb94lq8	188	24	the	the	DT
cord-264532-xfb94lq8	188	25	model	model	NN
cord-264532-xfb94lq8	188	26	used	use	VBN
cord-264532-xfb94lq8	188	27	to	to	TO
cord-264532-xfb94lq8	188	28	calculate	calculate	VB
cord-264532-xfb94lq8	188	29	the	the	DT
cord-264532-xfb94lq8	188	30	optimum	optimum	JJ
cord-264532-xfb94lq8	188	31	(	(	-LRB-
cord-264532-xfb94lq8	188	32	that	that	IN
cord-264532-xfb94lq8	188	33	the	the	DT
cord-264532-xfb94lq8	188	34	assumed	assumed	JJ
cord-264532-xfb94lq8	188	35	trade	trade	NN
cord-264532-xfb94lq8	188	36	-	-	HYPH
cord-264532-xfb94lq8	188	37	off	off	NN
cord-264532-xfb94lq8	188	38	did	do	VBD
cord-264532-xfb94lq8	188	39	not	not	RB
cord-264532-xfb94lq8	188	40	match	match	VB
cord-264532-xfb94lq8	188	41	the	the	DT
cord-264532-xfb94lq8	188	42	T7	T7	NNP
cord-264532-xfb94lq8	188	43	trade	trade	NN
cord-264532-xfb94lq8	188	44	-	-	HYPH
cord-264532-xfb94lq8	188	45	off	off	NN
cord-264532-xfb94lq8	188	46	)	)	-RRB-
cord-264532-xfb94lq8	188	47	.	.	.
cord-264532-xfb94lq8	189	1	The	the	DT
cord-264532-xfb94lq8	189	2	failure	failure	NN
cord-264532-xfb94lq8	189	3	to	to	TO
cord-264532-xfb94lq8	189	4	evolve	evolve	VB
cord-264532-xfb94lq8	189	5	is	be	VBZ
cord-264532-xfb94lq8	189	6	a	a	DT
cord-264532-xfb94lq8	189	7	special	special	JJ
cord-264532-xfb94lq8	189	8	case	case	NN
cord-264532-xfb94lq8	189	9	of	of	IN
cord-264532-xfb94lq8	189	10	our	-PRON-	PRP$
cord-264532-xfb94lq8	189	11	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	189	12	model	model	NN
cord-264532-xfb94lq8	189	13	,	,	,
cord-264532-xfb94lq8	189	14	and	and	CC
cord-264532-xfb94lq8	189	15	presumably	presumably	RB
cord-264532-xfb94lq8	189	16	,	,	,
cord-264532-xfb94lq8	189	17	the	the	DT
cord-264532-xfb94lq8	189	18	virus	virus	NN
cord-264532-xfb94lq8	189	19	would	would	MD
cord-264532-xfb94lq8	189	20	have	have	VB
cord-264532-xfb94lq8	189	21	evolved	evolve	VBN
cord-264532-xfb94lq8	189	22	after	after	IN
cord-264532-xfb94lq8	189	23	sufficient	sufficient	JJ
cord-264532-xfb94lq8	189	24	time	time	NN
cord-264532-xfb94lq8	189	25	.	.	.
cord-264532-xfb94lq8	190	1	The	the	DT
cord-264532-xfb94lq8	190	2	failure	failure	NN
cord-264532-xfb94lq8	190	3	to	to	TO
cord-264532-xfb94lq8	190	4	attain	attain	VB
cord-264532-xfb94lq8	190	5	the	the	DT
cord-264532-xfb94lq8	190	6	optimum	optimum	NN
cord-264532-xfb94lq8	190	7	despite	despite	IN
cord-264532-xfb94lq8	190	8	evolution	evolution	NN
cord-264532-xfb94lq8	190	9	in	in	IN
cord-264532-xfb94lq8	190	10	the	the	DT
cord-264532-xfb94lq8	190	11	other	other	JJ
cord-264532-xfb94lq8	190	12	replicate	replicate	NN
cord-264532-xfb94lq8	190	13	is	be	VBZ
cord-264532-xfb94lq8	190	14	presumably	presumably	RB
cord-264532-xfb94lq8	190	15	a	a	DT
cord-264532-xfb94lq8	190	16	failure	failure	NN
cord-264532-xfb94lq8	190	17	to	to	TO
cord-264532-xfb94lq8	190	18	calculate	calculate	VB
cord-264532-xfb94lq8	190	19	the	the	DT
cord-264532-xfb94lq8	190	20	true	true	JJ
cord-264532-xfb94lq8	190	21	optimum	optimum	NN
cord-264532-xfb94lq8	190	22	,	,	,
cord-264532-xfb94lq8	190	23	and	and	CC
cord-264532-xfb94lq8	190	24	thus	thus	RB
cord-264532-xfb94lq8	190	25	not	not	RB
cord-264532-xfb94lq8	190	26	an	an	DT
cord-264532-xfb94lq8	190	27	illustration	illustration	NN
cord-264532-xfb94lq8	190	28	of	of	IN
cord-264532-xfb94lq8	190	29	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	190	30	dynamics	dynamic	NNS
cord-264532-xfb94lq8	190	31	,	,	,
cord-264532-xfb94lq8	190	32	unless	unless	IN
cord-264532-xfb94lq8	190	33	it	-PRON-	PRP
cord-264532-xfb94lq8	190	34	could	could	MD
cord-264532-xfb94lq8	190	35	be	be	VB
cord-264532-xfb94lq8	190	36	shown	show	VBN
cord-264532-xfb94lq8	190	37	that	that	IN
cord-264532-xfb94lq8	190	38	the	the	DT
cord-264532-xfb94lq8	190	39	predicted	predict	VBN
cord-264532-xfb94lq8	190	40	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	190	41	would	would	MD
cord-264532-xfb94lq8	190	42	eventually	eventually	RB
cord-264532-xfb94lq8	190	43	be	be	VB
cord-264532-xfb94lq8	190	44	obtained	obtain	VBN
cord-264532-xfb94lq8	190	45	given	give	VBN
cord-264532-xfb94lq8	190	46	sufficient	sufficient	JJ
cord-264532-xfb94lq8	190	47	time	time	NN
cord-264532-xfb94lq8	190	48	.	.	.
cord-264532-xfb94lq8	191	1	Overall	overall	RB
cord-264532-xfb94lq8	191	2	,	,	,
cord-264532-xfb94lq8	191	3	this	this	DT
cord-264532-xfb94lq8	191	4	experimental	experimental	JJ
cord-264532-xfb94lq8	191	5	study	study	NN
cord-264532-xfb94lq8	191	6	illustrates	illustrate	VBZ
cord-264532-xfb94lq8	191	7	how	how	WRB
cord-264532-xfb94lq8	191	8	the	the	DT
cord-264532-xfb94lq8	191	9	measurement	measurement	NN
cord-264532-xfb94lq8	191	10	of	of	IN
cord-264532-xfb94lq8	191	11	deviation	deviation	NN
cord-264532-xfb94lq8	191	12	from	from	IN
cord-264532-xfb94lq8	191	13	optimality	optimality	NN
cord-264532-xfb94lq8	191	14	reflects	reflect	VBZ
cord-264532-xfb94lq8	191	15	on	on	IN
cord-264532-xfb94lq8	191	16	the	the	DT
cord-264532-xfb94lq8	191	17	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	191	18	model	model	NN
cord-264532-xfb94lq8	191	19	,	,	,
cord-264532-xfb94lq8	191	20	but	but	CC
cord-264532-xfb94lq8	191	21	only	only	RB
cord-264532-xfb94lq8	191	22	when	when	WRB
cord-264532-xfb94lq8	191	23	the	the	DT
cord-264532-xfb94lq8	191	24	basis	basis	NN
cord-264532-xfb94lq8	191	25	for	for	IN
cord-264532-xfb94lq8	191	26	nonoptimality	nonoptimality	NN
cord-264532-xfb94lq8	191	27	is	be	VBZ
cord-264532-xfb94lq8	191	28	understood	understand	VBN
cord-264532-xfb94lq8	191	29	.	.	.
cord-264532-xfb94lq8	192	1	It	-PRON-	PRP
cord-264532-xfb94lq8	192	2	is	be	VBZ
cord-264532-xfb94lq8	192	3	no	no	DT
cord-264532-xfb94lq8	192	4	doubt	doubt	RB
cord-264532-xfb94lq8	192	5	rare	rare	JJ
cord-264532-xfb94lq8	192	6	that	that	IN
cord-264532-xfb94lq8	192	7	a	a	DT
cord-264532-xfb94lq8	192	8	parasite	parasite	NN
cord-264532-xfb94lq8	192	9	optimum	optimum	NN
cord-264532-xfb94lq8	192	10	is	be	VBZ
cord-264532-xfb94lq8	192	11	known	know	VBN
cord-264532-xfb94lq8	192	12	and	and	CC
cord-264532-xfb94lq8	192	13	that	that	IN
cord-264532-xfb94lq8	192	14	evolution	evolution	NN
cord-264532-xfb94lq8	192	15	toward	toward	IN
cord-264532-xfb94lq8	192	16	the	the	DT
cord-264532-xfb94lq8	192	17	optimum	optimum	NN
cord-264532-xfb94lq8	192	18	can	can	MD
cord-264532-xfb94lq8	192	19	be	be	VB
cord-264532-xfb94lq8	192	20	observed	observe	VBN
cord-264532-xfb94lq8	192	21	;	;	:
cord-264532-xfb94lq8	192	22	repetition	repetition	NN
cord-264532-xfb94lq8	192	23	of	of	IN
cord-264532-xfb94lq8	192	24	this	this	DT
cord-264532-xfb94lq8	192	25	phage	phage	NN
cord-264532-xfb94lq8	192	26	experiment	experiment	NN
cord-264532-xfb94lq8	192	27	seems	seem	VBZ
cord-264532-xfb94lq8	192	28	especially	especially	RB
cord-264532-xfb94lq8	192	29	difficult	difficult	JJ
cord-264532-xfb94lq8	192	30	for	for	IN
cord-264532-xfb94lq8	192	31	parasites	parasite	NNS
cord-264532-xfb94lq8	192	32	of	of	IN
cord-264532-xfb94lq8	192	33	multicellular	multicellular	JJ
cord-264532-xfb94lq8	192	34	hosts	host	NNS
cord-264532-xfb94lq8	192	35	.	.	.
cord-264532-xfb94lq8	193	1	The	the	DT
cord-264532-xfb94lq8	193	2	bacteriophage	bacteriophage	NN
cord-264532-xfb94lq8	193	3	study	study	NN
cord-264532-xfb94lq8	193	4	benefited	benefit	VBD
cord-264532-xfb94lq8	193	5	from	from	IN
cord-264532-xfb94lq8	193	6	the	the	DT
cord-264532-xfb94lq8	193	7	fact	fact	NN
cord-264532-xfb94lq8	193	8	that	that	IN
cord-264532-xfb94lq8	193	9	the	the	DT
cord-264532-xfb94lq8	193	10	optimality	optimality	NN
cord-264532-xfb94lq8	193	11	model	model	NN
cord-264532-xfb94lq8	193	12	required	require	VBN
cord-264532-xfb94lq8	193	13	only	only	RB
cord-264532-xfb94lq8	193	14	linearity	linearity	NN
cord-264532-xfb94lq8	193	15	of	of	IN
cord-264532-xfb94lq8	193	16	the	the	DT
cord-264532-xfb94lq8	193	17	trade	trade	NN
cord-264532-xfb94lq8	193	18	-	-	HYPH
cord-264532-xfb94lq8	193	19	off	off	NN
cord-264532-xfb94lq8	193	20	,	,	,
cord-264532-xfb94lq8	193	21	and	and	CC
cord-264532-xfb94lq8	193	22	that	that	IN
cord-264532-xfb94lq8	193	23	the	the	DT
cord-264532-xfb94lq8	193	24	slope	slope	NN
cord-264532-xfb94lq8	193	25	of	of	IN
cord-264532-xfb94lq8	193	26	the	the	DT
cord-264532-xfb94lq8	193	27	trade	trade	NN
cord-264532-xfb94lq8	193	28	-	-	HYPH
cord-264532-xfb94lq8	193	29	off	off	NN
cord-264532-xfb94lq8	193	30	did	do	VBD
cord-264532-xfb94lq8	193	31	not	not	RB
cord-264532-xfb94lq8	193	32	affect	affect	VB
cord-264532-xfb94lq8	193	33	the	the	DT
cord-264532-xfb94lq8	193	34	optimum	optimum	JJ
cord-264532-xfb94lq8	193	35	(	(	-LRB-
cord-264532-xfb94lq8	193	36	and	and	CC
cord-264532-xfb94lq8	193	37	even	even	RB
cord-264532-xfb94lq8	193	38	the	the	DT
cord-264532-xfb94lq8	193	39	assumption	assumption	NN
cord-264532-xfb94lq8	193	40	of	of	IN
cord-264532-xfb94lq8	193	41	this	this	DT
cord-264532-xfb94lq8	193	42	generality	generality	NN
cord-264532-xfb94lq8	193	43	appears	appear	VBZ
cord-264532-xfb94lq8	193	44	to	to	TO
cord-264532-xfb94lq8	193	45	have	have	VB
cord-264532-xfb94lq8	193	46	been	be	VBN
cord-264532-xfb94lq8	193	47	wrong	wrong	JJ
cord-264532-xfb94lq8	193	48	)	)	-RRB-
cord-264532-xfb94lq8	193	49	.	.	.
cord-264532-xfb94lq8	194	1	Such	such	JJ
cord-264532-xfb94lq8	194	2	generality	generality	NN
cord-264532-xfb94lq8	194	3	may	may	MD
cord-264532-xfb94lq8	194	4	be	be	VB
cord-264532-xfb94lq8	194	5	rare	rare	JJ
cord-264532-xfb94lq8	194	6	,	,	,
cord-264532-xfb94lq8	194	7	and	and	CC
cord-264532-xfb94lq8	194	8	quantitative	quantitative	JJ
cord-264532-xfb94lq8	194	9	knowledge	knowledge	NN
cord-264532-xfb94lq8	194	10	of	of	IN
cord-264532-xfb94lq8	194	11	the	the	DT
cord-264532-xfb94lq8	194	12	trade	trade	NN
cord-264532-xfb94lq8	194	13	-	-	HYPH
cord-264532-xfb94lq8	194	14	off	off	NN
cord-264532-xfb94lq8	194	15	may	may	MD
cord-264532-xfb94lq8	194	16	be	be	VB
cord-264532-xfb94lq8	194	17	necessary	necessary	JJ
cord-264532-xfb94lq8	194	18	to	to	TO
cord-264532-xfb94lq8	194	19	predict	predict	VB
cord-264532-xfb94lq8	194	20	the	the	DT
cord-264532-xfb94lq8	194	21	optimum	optimum	NN
cord-264532-xfb94lq8	194	22	in	in	IN
cord-264532-xfb94lq8	194	23	most	most	JJS
cord-264532-xfb94lq8	194	24	systems	system	NNS
cord-264532-xfb94lq8	194	25	.	.	.
cord-264532-xfb94lq8	195	1	Even	even	RB
cord-264532-xfb94lq8	195	2	if	if	IN
cord-264532-xfb94lq8	195	3	an	an	DT
cord-264532-xfb94lq8	195	4	optimum	optimum	NN
cord-264532-xfb94lq8	195	5	can	can	MD
cord-264532-xfb94lq8	195	6	not	not	RB
cord-264532-xfb94lq8	195	7	be	be	VB
cord-264532-xfb94lq8	195	8	calculated	calculate	VBN
cord-264532-xfb94lq8	195	9	a	a	DT
cord-264532-xfb94lq8	195	10	priori	priori	FW
cord-264532-xfb94lq8	195	11	,	,	,
cord-264532-xfb94lq8	195	12	it	-PRON-	PRP
cord-264532-xfb94lq8	195	13	may	may	MD
cord-264532-xfb94lq8	195	14	be	be	VB
cord-264532-xfb94lq8	195	15	determined	determine	VBN
cord-264532-xfb94lq8	195	16	empirically	empirically	RB
cord-264532-xfb94lq8	195	17	in	in	IN
cord-264532-xfb94lq8	195	18	an	an	DT
cord-264532-xfb94lq8	195	19	experiment	experiment	NN
cord-264532-xfb94lq8	195	20	,	,	,
cord-264532-xfb94lq8	195	21	as	as	IN
cord-264532-xfb94lq8	195	22	a	a	DT
cord-264532-xfb94lq8	195	23	long	long	JJ
cord-264532-xfb94lq8	195	24	-	-	HYPH
cord-264532-xfb94lq8	195	25	term	term	NN
cord-264532-xfb94lq8	195	26	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	195	27	that	that	WDT
cord-264532-xfb94lq8	195	28	is	be	VBZ
cord-264532-xfb94lq8	195	29	attained	attain	VBN
cord-264532-xfb94lq8	195	30	and	and	CC
cord-264532-xfb94lq8	195	31	maintained	maintain	VBN
cord-264532-xfb94lq8	195	32	.	.	.
cord-264532-xfb94lq8	196	1	The	the	DT
cord-264532-xfb94lq8	196	2	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	196	3	approach	approach	NN
cord-264532-xfb94lq8	196	4	to	to	IN
cord-264532-xfb94lq8	196	5	this	this	DT
cord-264532-xfb94lq8	196	6	optimum	optimum	NN
cord-264532-xfb94lq8	196	7	from	from	IN
cord-264532-xfb94lq8	196	8	different	different	JJ
cord-264532-xfb94lq8	196	9	starting	starting	NN
cord-264532-xfb94lq8	196	10	points	point	NNS
cord-264532-xfb94lq8	196	11	then	then	RB
cord-264532-xfb94lq8	196	12	provides	provide	VBZ
cord-264532-xfb94lq8	196	13	insight	insight	NN
cord-264532-xfb94lq8	196	14	to	to	IN
cord-264532-xfb94lq8	196	15	the	the	DT
cord-264532-xfb94lq8	196	16	dynamical	dynamical	JJ
cord-264532-xfb94lq8	196	17	behavior	behavior	NN
cord-264532-xfb94lq8	196	18	relevant	relevant	JJ
cord-264532-xfb94lq8	196	19	to	to	IN
cord-264532-xfb94lq8	196	20	the	the	DT
cord-264532-xfb94lq8	196	21	perspective	perspective	NN
cord-264532-xfb94lq8	196	22	given	give	VBN
cord-264532-xfb94lq8	196	23	here	here	RB
cord-264532-xfb94lq8	196	24	.	.	.
cord-264532-xfb94lq8	197	1	Insight	Insight	NNP
cord-264532-xfb94lq8	197	2	may	may	MD
cord-264532-xfb94lq8	197	3	also	also	RB
cord-264532-xfb94lq8	197	4	be	be	VB
cord-264532-xfb94lq8	197	5	gained	gain	VBN
cord-264532-xfb94lq8	197	6	from	from	IN
cord-264532-xfb94lq8	197	7	observations	observation	NNS
cord-264532-xfb94lq8	197	8	of	of	IN
cord-264532-xfb94lq8	197	9	parasites	parasite	NNS
cord-264532-xfb94lq8	197	10	under	under	IN
cord-264532-xfb94lq8	197	11	natural	natural	JJ
cord-264532-xfb94lq8	197	12	conditions	condition	NNS
cord-264532-xfb94lq8	197	13	.	.	.
cord-264532-xfb94lq8	198	1	Some	some	DT
cord-264532-xfb94lq8	198	2	basic	basic	JJ
cord-264532-xfb94lq8	198	3	characteristics	characteristic	NNS
cord-264532-xfb94lq8	198	4	predispose	predispose	VBP
cord-264532-xfb94lq8	198	5	a	a	DT
cord-264532-xfb94lq8	198	6	parasite	parasite	NN
cord-264532-xfb94lq8	198	7	toward	toward	IN
cord-264532-xfb94lq8	198	8	delayed	delay	VBN
cord-264532-xfb94lq8	198	9	-	-	HYPH
cord-264532-xfb94lq8	198	10	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	198	11	virulence	virulence	NN
cord-264532-xfb94lq8	198	12	,	,	,
cord-264532-xfb94lq8	198	13	and	and	CC
cord-264532-xfb94lq8	198	14	the	the	DT
cord-264532-xfb94lq8	198	15	following	follow	VBG
cord-264532-xfb94lq8	198	16	examples	example	NNS
cord-264532-xfb94lq8	198	17	of	of	IN
cord-264532-xfb94lq8	198	18	vertebrate	vertebrate	JJ
cord-264532-xfb94lq8	198	19	parasites	parasite	NNS
cord-264532-xfb94lq8	198	20	(	(	-LRB-
cord-264532-xfb94lq8	198	21	all	all	DT
cord-264532-xfb94lq8	198	22	viruses	virus	NNS
cord-264532-xfb94lq8	198	23	)	)	-RRB-
cord-264532-xfb94lq8	198	24	illustrate	illustrate	VBP
cord-264532-xfb94lq8	198	25	how	how	WRB
cord-264532-xfb94lq8	198	26	one	one	PRP
cord-264532-xfb94lq8	198	27	may	may	MD
cord-264532-xfb94lq8	198	28	begin	begin	VB
cord-264532-xfb94lq8	198	29	looking	look	VBG
cord-264532-xfb94lq8	198	30	for	for	IN
cord-264532-xfb94lq8	198	31	candidates	candidate	NNS
cord-264532-xfb94lq8	198	32	.	.	.
cord-264532-xfb94lq8	199	1	These	these	DT
cord-264532-xfb94lq8	199	2	examples	example	NNS
cord-264532-xfb94lq8	199	3	illustrate	illustrate	VBP
cord-264532-xfb94lq8	199	4	that	that	IN
cord-264532-xfb94lq8	199	5	not	not	RB
cord-264532-xfb94lq8	199	6	all	all	DT
cord-264532-xfb94lq8	199	7	parasites	parasite	NNS
cord-264532-xfb94lq8	199	8	exhibit	exhibit	VBP
cord-264532-xfb94lq8	199	9	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	199	10	dynamics	dynamic	NNS
cord-264532-xfb94lq8	199	11	,	,	,
cord-264532-xfb94lq8	199	12	and	and	CC
cord-264532-xfb94lq8	199	13	even	even	RB
cord-264532-xfb94lq8	199	14	among	among	IN
cord-264532-xfb94lq8	199	15	those	those	DT
cord-264532-xfb94lq8	199	16	that	that	WDT
cord-264532-xfb94lq8	199	17	do	do	VBP
cord-264532-xfb94lq8	199	18	,	,	,
cord-264532-xfb94lq8	199	19	the	the	DT
cord-264532-xfb94lq8	199	20	frequency	frequency	NN
cord-264532-xfb94lq8	199	21	of	of	IN
cord-264532-xfb94lq8	199	22	the	the	DT
cord-264532-xfb94lq8	199	23	phenomenon	phenomenon	NN
cord-264532-xfb94lq8	199	24	varies	vary	VBZ
cord-264532-xfb94lq8	199	25	considerably	considerably	RB
cord-264532-xfb94lq8	199	26	.	.	.
cord-264532-xfb94lq8	200	1	The	the	DT
cord-264532-xfb94lq8	200	2	primary	primary	JJ
cord-264532-xfb94lq8	200	3	criterion	criterion	NN
cord-264532-xfb94lq8	200	4	that	that	WDT
cord-264532-xfb94lq8	200	5	can	can	MD
cord-264532-xfb94lq8	200	6	be	be	VB
cord-264532-xfb94lq8	200	7	used	use	VBN
cord-264532-xfb94lq8	200	8	in	in	IN
cord-264532-xfb94lq8	200	9	considering	consider	VBG
cord-264532-xfb94lq8	200	10	the	the	DT
cord-264532-xfb94lq8	200	11	invasion	invasion	NN
cord-264532-xfb94lq8	200	12	threshold	threshold	NN
cord-264532-xfb94lq8	200	13	perspective	perspective	NN
cord-264532-xfb94lq8	200	14	is	be	VBZ
cord-264532-xfb94lq8	200	15	that	that	IN
cord-264532-xfb94lq8	200	16	a	a	DT
cord-264532-xfb94lq8	200	17	host	host	NN
cord-264532-xfb94lq8	200	18	experiences	experience	VBZ
cord-264532-xfb94lq8	200	19	periodic	periodic	JJ
cord-264532-xfb94lq8	200	20	invasion	invasion	NN
cord-264532-xfb94lq8	200	21	by	by	IN
cord-264532-xfb94lq8	200	22	new	new	JJ
cord-264532-xfb94lq8	200	23	parasite	parasite	NN
cord-264532-xfb94lq8	200	24	mutants	mutant	NNS
cord-264532-xfb94lq8	200	25	.	.	.
cord-264532-xfb94lq8	201	1	As	as	IN
cord-264532-xfb94lq8	201	2	noted	note	VBN
cord-264532-xfb94lq8	201	3	above	above	RB
cord-264532-xfb94lq8	201	4	,	,	,
cord-264532-xfb94lq8	201	5	this	this	DT
cord-264532-xfb94lq8	201	6	criterion	criterion	NN
cord-264532-xfb94lq8	201	7	does	do	VBZ
cord-264532-xfb94lq8	201	8	not	not	RB
cord-264532-xfb94lq8	201	9	rule	rule	VB
cord-264532-xfb94lq8	201	10	out	out	RP
cord-264532-xfb94lq8	201	11	the	the	DT
cord-264532-xfb94lq8	201	12	Lenski	Lenski	NNP
cord-264532-xfb94lq8	201	13	and	and	CC
cord-264532-xfb94lq8	201	14	May	May	NNP
cord-264532-xfb94lq8	201	15	(	(	-LRB-
cord-264532-xfb94lq8	201	16	1994	1994	CD
cord-264532-xfb94lq8	201	17	)	)	-RRB-
cord-264532-xfb94lq8	201	18	model	model	NN
cord-264532-xfb94lq8	201	19	.	.	.
cord-264532-xfb94lq8	202	1	Thus	thus	RB
cord-264532-xfb94lq8	202	2	,	,	,
cord-264532-xfb94lq8	202	3	a	a	DT
cord-264532-xfb94lq8	202	4	second	second	JJ
cord-264532-xfb94lq8	202	5	important	important	JJ
cord-264532-xfb94lq8	202	6	question	question	NN
cord-264532-xfb94lq8	202	7	,	,	,
cord-264532-xfb94lq8	202	8	but	but	CC
cord-264532-xfb94lq8	202	9	one	one	NN
cord-264532-xfb94lq8	202	10	that	that	WDT
cord-264532-xfb94lq8	202	11	can	can	MD
cord-264532-xfb94lq8	202	12	rarely	rarely	RB
cord-264532-xfb94lq8	202	13	be	be	VB
cord-264532-xfb94lq8	202	14	answered	answer	VBN
cord-264532-xfb94lq8	202	15	,	,	,
cord-264532-xfb94lq8	202	16	is	be	VBZ
cord-264532-xfb94lq8	202	17	whether	whether	IN
cord-264532-xfb94lq8	202	18	the	the	DT
cord-264532-xfb94lq8	202	19	parasites	parasite	NNS
cord-264532-xfb94lq8	202	20	are	be	VBP
cord-264532-xfb94lq8	202	21	far	far	RB
cord-264532-xfb94lq8	202	22	off	off	IN
cord-264532-xfb94lq8	202	23	the	the	DT
cord-264532-xfb94lq8	202	24	optimum	optimum	NN
cord-264532-xfb94lq8	202	25	.	.	.
cord-264532-xfb94lq8	203	1	We	-PRON-	PRP
cord-264532-xfb94lq8	203	2	start	start	VBP
cord-264532-xfb94lq8	203	3	with	with	IN
cord-264532-xfb94lq8	203	4	two	two	CD
cord-264532-xfb94lq8	203	5	pathogens	pathogen	NNS
cord-264532-xfb94lq8	203	6	that	that	WDT
cord-264532-xfb94lq8	203	7	elicit	elicit	VBP
cord-264532-xfb94lq8	203	8	host	host	NN
cord-264532-xfb94lq8	203	9	immunity	immunity	NN
cord-264532-xfb94lq8	203	10	but	but	CC
cord-264532-xfb94lq8	203	11	clearly	clearly	RB
cord-264532-xfb94lq8	203	12	do	do	VBP
cord-264532-xfb94lq8	203	13	not	not	RB
cord-264532-xfb94lq8	203	14	exhibit	exhibit	VB
cord-264532-xfb94lq8	203	15	repeated	repeat	VBN
cord-264532-xfb94lq8	203	16	invasions	invasion	NNS
cord-264532-xfb94lq8	203	17	by	by	IN
cord-264532-xfb94lq8	203	18	mutants	mutant	NNS
cord-264532-xfb94lq8	203	19	that	that	WDT
cord-264532-xfb94lq8	203	20	escape	escape	VBP
cord-264532-xfb94lq8	203	21	immunity	immunity	NN
cord-264532-xfb94lq8	203	22	.	.	.
cord-264532-xfb94lq8	204	1	Humans	human	NNS
cord-264532-xfb94lq8	204	2	are	be	VBP
cord-264532-xfb94lq8	204	3	the	the	DT
cord-264532-xfb94lq8	204	4	only	only	RB
cord-264532-xfb94lq8	204	5	known	know	VBN
cord-264532-xfb94lq8	204	6	natural	natural	JJ
cord-264532-xfb94lq8	204	7	hosts	host	NNS
cord-264532-xfb94lq8	204	8	for	for	IN
cord-264532-xfb94lq8	204	9	measles	measle	NNS
cord-264532-xfb94lq8	204	10	and	and	CC
cord-264532-xfb94lq8	204	11	polio	polio	NN
cord-264532-xfb94lq8	204	12	viruses	virus	NNS
cord-264532-xfb94lq8	204	13	.	.	.
cord-264532-xfb94lq8	205	1	Successful	successful	JJ
cord-264532-xfb94lq8	205	2	vaccines	vaccine	NNS
cord-264532-xfb94lq8	205	3	have	have	VBP
cord-264532-xfb94lq8	205	4	greatly	greatly	RB
cord-264532-xfb94lq8	205	5	reduced	reduce	VBN
cord-264532-xfb94lq8	205	6	the	the	DT
cord-264532-xfb94lq8	205	7	incidence	incidence	NN
cord-264532-xfb94lq8	205	8	of	of	IN
cord-264532-xfb94lq8	205	9	both	both	DT
cord-264532-xfb94lq8	205	10	infections	infection	NNS
cord-264532-xfb94lq8	205	11	,	,	,
cord-264532-xfb94lq8	205	12	and	and	CC
cord-264532-xfb94lq8	205	13	the	the	DT
cord-264532-xfb94lq8	205	14	vaccines	vaccine	NNS
cord-264532-xfb94lq8	205	15	derived	derive	VBN
cord-264532-xfb94lq8	205	16	from	from	IN
cord-264532-xfb94lq8	205	17	decades	decade	NNS
cord-264532-xfb94lq8	205	18	-	-	HYPH
cord-264532-xfb94lq8	205	19	old	old	JJ
cord-264532-xfb94lq8	205	20	isolates	isolate	NNS
cord-264532-xfb94lq8	205	21	have	have	VBP
cord-264532-xfb94lq8	205	22	remained	remain	VBN
cord-264532-xfb94lq8	205	23	effective	effective	JJ
cord-264532-xfb94lq8	205	24	without	without	IN
cord-264532-xfb94lq8	205	25	apparent	apparent	JJ
cord-264532-xfb94lq8	205	26	evolution	evolution	NN
cord-264532-xfb94lq8	205	27	of	of	IN
cord-264532-xfb94lq8	205	28	novel	novel	JJ
cord-264532-xfb94lq8	205	29	antigens	antigen	NNS
cord-264532-xfb94lq8	205	30	that	that	WDT
cord-264532-xfb94lq8	205	31	escape	escape	VBP
cord-264532-xfb94lq8	205	32	vaccine	vaccine	NN
cord-264532-xfb94lq8	205	33	-	-	HYPH
cord-264532-xfb94lq8	205	34	induced	induce	VBN
cord-264532-xfb94lq8	205	35	immunity	immunity	NN
cord-264532-xfb94lq8	205	36	(	(	-LRB-
cord-264532-xfb94lq8	205	37	Schrag	Schrag	NNP
cord-264532-xfb94lq8	205	38	et	et	NNP
cord-264532-xfb94lq8	205	39	al	al	NNP
cord-264532-xfb94lq8	205	40	.	.	.
cord-264532-xfb94lq8	206	1	1999	1999	CD
cord-264532-xfb94lq8	206	2	;	;	:
cord-264532-xfb94lq8	206	3	Macadam	Macadam	NNP
cord-264532-xfb94lq8	206	4	et	et	FW
cord-264532-xfb94lq8	206	5	al	al	NNP
cord-264532-xfb94lq8	206	6	.	.	.
cord-264532-xfb94lq8	206	7	2006	2006	CD
cord-264532-xfb94lq8	206	8	)	)	-RRB-
cord-264532-xfb94lq8	206	9	.	.	.
cord-264532-xfb94lq8	207	1	Both	both	DT
cord-264532-xfb94lq8	207	2	viruses	virus	NNS
cord-264532-xfb94lq8	207	3	,	,	,
cord-264532-xfb94lq8	207	4	therefore	therefore	RB
cord-264532-xfb94lq8	207	5	,	,	,
cord-264532-xfb94lq8	207	6	are	be	VBP
cord-264532-xfb94lq8	207	7	good	good	JJ
cord-264532-xfb94lq8	207	8	candidates	candidate	NNS
cord-264532-xfb94lq8	207	9	for	for	IN
cord-264532-xfb94lq8	207	10	the	the	DT
cord-264532-xfb94lq8	207	11	R	r	NN
cord-264532-xfb94lq8	207	12	0	0	CD
cord-264532-xfb94lq8	207	13	maximization	maximization	NN
cord-264532-xfb94lq8	207	14	model	model	NN
cord-264532-xfb94lq8	207	15	,	,	,
cord-264532-xfb94lq8	207	16	but	but	CC
cord-264532-xfb94lq8	207	17	their	-PRON-	PRP$
cord-264532-xfb94lq8	207	18	virulence	virulence	NN
cord-264532-xfb94lq8	207	19	optima	optima	NNP
cord-264532-xfb94lq8	207	20	are	be	VBP
cord-264532-xfb94lq8	207	21	difficult	difficult	JJ
cord-264532-xfb94lq8	207	22	to	to	TO
cord-264532-xfb94lq8	207	23	establish	establish	VB
cord-264532-xfb94lq8	207	24	,	,	,
cord-264532-xfb94lq8	207	25	and	and	CC
cord-264532-xfb94lq8	207	26	alternatives	alternative	NNS
cord-264532-xfb94lq8	207	27	to	to	IN
cord-264532-xfb94lq8	207	28	the	the	DT
cord-264532-xfb94lq8	207	29	R	r	NN
cord-264532-xfb94lq8	207	30	0	0	CD
cord-264532-xfb94lq8	207	31	model	model	NN
cord-264532-xfb94lq8	207	32	have	have	VBP
cord-264532-xfb94lq8	207	33	been	be	VBN
cord-264532-xfb94lq8	207	34	proposed	propose	VBN
cord-264532-xfb94lq8	207	35	at	at	IN
cord-264532-xfb94lq8	207	36	least	least	JJS
cord-264532-xfb94lq8	207	37	for	for	IN
cord-264532-xfb94lq8	207	38	polio	polio	NN
cord-264532-xfb94lq8	207	39	(	(	-LRB-
cord-264532-xfb94lq8	207	40	Levin	Levin	NNP
cord-264532-xfb94lq8	207	41	and	and	CC
cord-264532-xfb94lq8	207	42	Bull	Bull	NNP
cord-264532-xfb94lq8	207	43	1994	1994	CD
cord-264532-xfb94lq8	207	44	;	;	:
cord-264532-xfb94lq8	207	45	Frank	Frank	NNP
cord-264532-xfb94lq8	207	46	1996	1996	CD
cord-264532-xfb94lq8	207	47	)	)	-RRB-
cord-264532-xfb94lq8	207	48	.	.	.
cord-264532-xfb94lq8	208	1	In	in	IN
cord-264532-xfb94lq8	208	2	addition	addition	NN
cord-264532-xfb94lq8	208	3	,	,	,
cord-264532-xfb94lq8	208	4	the	the	DT
cord-264532-xfb94lq8	208	5	virulence	virulence	NN
cord-264532-xfb94lq8	208	6	of	of	IN
cord-264532-xfb94lq8	208	7	measles	measle	NNS
cord-264532-xfb94lq8	208	8	is	be	VBZ
cord-264532-xfb94lq8	208	9	notoriously	notoriously	RB
cord-264532-xfb94lq8	208	10	sensitive	sensitive	JJ
cord-264532-xfb94lq8	208	11	to	to	TO
cord-264532-xfb94lq8	208	12	host	host	VB
cord-264532-xfb94lq8	208	13	nutritional	nutritional	JJ
cord-264532-xfb94lq8	208	14	status	status	NN
cord-264532-xfb94lq8	208	15	,	,	,
cord-264532-xfb94lq8	208	16	so	so	CC
cord-264532-xfb94lq8	208	17	it	-PRON-	PRP
cord-264532-xfb94lq8	208	18	is	be	VBZ
cord-264532-xfb94lq8	208	19	not	not	RB
cord-264532-xfb94lq8	208	20	clear	clear	JJ
cord-264532-xfb94lq8	208	21	what	what	WDT
cord-264532-xfb94lq8	208	22	level	level	NN
cord-264532-xfb94lq8	208	23	of	of	IN
cord-264532-xfb94lq8	208	24	virulence	virulence	NN
cord-264532-xfb94lq8	208	25	to	to	TO
cord-264532-xfb94lq8	208	26	apply	apply	VB
cord-264532-xfb94lq8	208	27	to	to	IN
cord-264532-xfb94lq8	208	28	the	the	DT
cord-264532-xfb94lq8	208	29	model	model	NN
cord-264532-xfb94lq8	208	30	.	.	.
cord-264532-xfb94lq8	209	1	Even	even	RB
cord-264532-xfb94lq8	209	2	without	without	IN
cord-264532-xfb94lq8	209	3	knowing	know	VBG
cord-264532-xfb94lq8	209	4	whether	whether	IN
cord-264532-xfb94lq8	209	5	these	these	DT
cord-264532-xfb94lq8	209	6	viruses	virus	NNS
cord-264532-xfb94lq8	209	7	have	have	VBP
cord-264532-xfb94lq8	209	8	achieved	achieve	VBN
cord-264532-xfb94lq8	209	9	an	an	DT
cord-264532-xfb94lq8	209	10	optimum	optimum	JJ
cord-264532-xfb94lq8	209	11	level	level	NN
cord-264532-xfb94lq8	209	12	of	of	IN
cord-264532-xfb94lq8	209	13	virulence	virulence	NN
cord-264532-xfb94lq8	209	14	,	,	,
cord-264532-xfb94lq8	209	15	both	both	DT
cord-264532-xfb94lq8	209	16	viruses	virus	NNS
cord-264532-xfb94lq8	209	17	appear	appear	VBP
cord-264532-xfb94lq8	209	18	to	to	TO
cord-264532-xfb94lq8	209	19	be	be	VB
cord-264532-xfb94lq8	209	20	good	good	JJ
cord-264532-xfb94lq8	209	21	candidates	candidate	NNS
cord-264532-xfb94lq8	209	22	for	for	IN
cord-264532-xfb94lq8	209	23	viruses	virus	NNS
cord-264532-xfb94lq8	209	24	that	that	WDT
cord-264532-xfb94lq8	209	25	violate	violate	VBP
cord-264532-xfb94lq8	209	26	the	the	DT
cord-264532-xfb94lq8	209	27	invasion	invasion	NN
cord-264532-xfb94lq8	209	28	threshold	threshold	NN
cord-264532-xfb94lq8	209	29	model	model	NN
cord-264532-xfb94lq8	209	30	(	(	-LRB-
cord-264532-xfb94lq8	209	31	at	at	IN
cord-264532-xfb94lq8	209	32	least	least	JJS
cord-264532-xfb94lq8	209	33	in	in	IN
cord-264532-xfb94lq8	209	34	contemporary	contemporary	JJ
cord-264532-xfb94lq8	209	35	populations	population	NNS
cord-264532-xfb94lq8	209	36	)	)	-RRB-
cord-264532-xfb94lq8	209	37	by	by	IN
cord-264532-xfb94lq8	209	38	virtue	virtue	NN
cord-264532-xfb94lq8	209	39	of	of	IN
cord-264532-xfb94lq8	209	40	their	-PRON-	PRP$
cord-264532-xfb94lq8	209	41	failure	failure	NN
cord-264532-xfb94lq8	209	42	to	to	TO
cord-264532-xfb94lq8	209	43	generate	generate	VB
cord-264532-xfb94lq8	209	44	escape	escape	NN
cord-264532-xfb94lq8	209	45	mutants	mutant	NNS
cord-264532-xfb94lq8	209	46	.	.	.
cord-264532-xfb94lq8	210	1	As	as	IN
cord-264532-xfb94lq8	210	2	an	an	DT
cord-264532-xfb94lq8	210	3	aside	aside	NN
cord-264532-xfb94lq8	210	4	,	,	,
cord-264532-xfb94lq8	210	5	the	the	DT
cord-264532-xfb94lq8	210	6	lack	lack	NN
cord-264532-xfb94lq8	210	7	of	of	IN
cord-264532-xfb94lq8	210	8	'	'	``
cord-264532-xfb94lq8	210	9	escape	escape	NN
cord-264532-xfb94lq8	210	10	'	'	''
cord-264532-xfb94lq8	210	11	mutants	mutant	NNS
cord-264532-xfb94lq8	210	12	capable	capable	JJ
cord-264532-xfb94lq8	210	13	of	of	IN
cord-264532-xfb94lq8	210	14	infecting	infect	VBG
cord-264532-xfb94lq8	210	15	immune	immune	JJ
cord-264532-xfb94lq8	210	16	hosts	host	NNS
cord-264532-xfb94lq8	210	17	is	be	VBZ
cord-264532-xfb94lq8	210	18	puzzling	puzzle	VBG
cord-264532-xfb94lq8	210	19	,	,	,
cord-264532-xfb94lq8	210	20	as	as	IN
cord-264532-xfb94lq8	210	21	both	both	DT
cord-264532-xfb94lq8	210	22	viruses	virus	NNS
cord-264532-xfb94lq8	210	23	have	have	VBP
cord-264532-xfb94lq8	210	24	RNA	RNA	NNP
cord-264532-xfb94lq8	210	25	genomes	genome	NNS
cord-264532-xfb94lq8	210	26	,	,	,
cord-264532-xfb94lq8	210	27	which	which	WDT
cord-264532-xfb94lq8	210	28	are	be	VBP
cord-264532-xfb94lq8	210	29	thought	think	VBN
cord-264532-xfb94lq8	210	30	to	to	TO
cord-264532-xfb94lq8	210	31	be	be	VB
cord-264532-xfb94lq8	210	32	prone	prone	JJ
cord-264532-xfb94lq8	210	33	to	to	IN
cord-264532-xfb94lq8	210	34	rapid	rapid	JJ
cord-264532-xfb94lq8	210	35	evolution	evolution	NN
cord-264532-xfb94lq8	210	36	.	.	.
cord-264532-xfb94lq8	211	1	Furthermore	furthermore	RB
cord-264532-xfb94lq8	211	2	,	,	,
cord-264532-xfb94lq8	211	3	three	three	CD
cord-264532-xfb94lq8	211	4	antigenically	antigenically	RB
cord-264532-xfb94lq8	211	5	distinct	distinct	JJ
cord-264532-xfb94lq8	211	6	polioviruses	poliovirus	NNS
cord-264532-xfb94lq8	211	7	are	be	VBP
cord-264532-xfb94lq8	211	8	known	know	VBN
cord-264532-xfb94lq8	211	9	(	(	-LRB-
cord-264532-xfb94lq8	211	10	and	and	CC
cord-264532-xfb94lq8	211	11	each	each	DT
cord-264532-xfb94lq8	211	12	is	be	VBZ
cord-264532-xfb94lq8	211	13	included	include	VBN
cord-264532-xfb94lq8	211	14	in	in	IN
cord-264532-xfb94lq8	211	15	the	the	DT
cord-264532-xfb94lq8	211	16	vaccine	vaccine	NN
cord-264532-xfb94lq8	211	17	)	)	-RRB-
cord-264532-xfb94lq8	211	18	,	,	,
cord-264532-xfb94lq8	211	19	yet	yet	CC
cord-264532-xfb94lq8	211	20	no	no	DT
cord-264532-xfb94lq8	211	21	others	other	NNS
cord-264532-xfb94lq8	211	22	have	have	VBP
cord-264532-xfb94lq8	211	23	evolved	evolve	VBN
cord-264532-xfb94lq8	211	24	in	in	IN
cord-264532-xfb94lq8	211	25	response	response	NN
cord-264532-xfb94lq8	211	26	to	to	IN
cord-264532-xfb94lq8	211	27	vaccine	vaccine	NN
cord-264532-xfb94lq8	211	28	pressure	pressure	NN
cord-264532-xfb94lq8	211	29	(	(	-LRB-
cord-264532-xfb94lq8	211	30	Macadam	Macadam	NNP
cord-264532-xfb94lq8	211	31	et	et	FW
cord-264532-xfb94lq8	211	32	al	al	NNP
cord-264532-xfb94lq8	211	33	.	.	.
cord-264532-xfb94lq8	211	34	2006	2006	CD
cord-264532-xfb94lq8	211	35	)	)	-RRB-
cord-264532-xfb94lq8	211	36	.	.	.
cord-264532-xfb94lq8	212	1	These	these	DT
cord-264532-xfb94lq8	212	2	two	two	CD
cord-264532-xfb94lq8	212	3	viruses	virus	NNS
cord-264532-xfb94lq8	212	4	highlight	highlight	VBP
cord-264532-xfb94lq8	212	5	the	the	DT
cord-264532-xfb94lq8	212	6	point	point	NN
cord-264532-xfb94lq8	212	7	that	that	IN
cord-264532-xfb94lq8	212	8	,	,	,
cord-264532-xfb94lq8	212	9	contrary	contrary	JJ
cord-264532-xfb94lq8	212	10	to	to	IN
cord-264532-xfb94lq8	212	11	common	common	JJ
cord-264532-xfb94lq8	212	12	perception	perception	NN
cord-264532-xfb94lq8	212	13	,	,	,
cord-264532-xfb94lq8	212	14	some	some	DT
cord-264532-xfb94lq8	212	15	parasites	parasite	NNS
cord-264532-xfb94lq8	212	16	may	may	MD
cord-264532-xfb94lq8	212	17	not	not	RB
cord-264532-xfb94lq8	212	18	be	be	VB
cord-264532-xfb94lq8	212	19	able	able	JJ
cord-264532-xfb94lq8	212	20	to	to	TO
cord-264532-xfb94lq8	212	21	adapt	adapt	VB
cord-264532-xfb94lq8	212	22	to	to	IN
cord-264532-xfb94lq8	212	23	altered	alter	VBN
cord-264532-xfb94lq8	212	24	environmental	environmental	JJ
cord-264532-xfb94lq8	212	25	conditions	condition	NNS
cord-264532-xfb94lq8	212	26	.	.	.
cord-264532-xfb94lq8	213	1	The	the	DT
cord-264532-xfb94lq8	213	2	flu	flu	NN
cord-264532-xfb94lq8	213	3	virus	virus	NN
cord-264532-xfb94lq8	213	4	is	be	VBZ
cord-264532-xfb94lq8	213	5	notorious	notorious	JJ
cord-264532-xfb94lq8	213	6	for	for	IN
cord-264532-xfb94lq8	213	7	its	-PRON-	PRP$
cord-264532-xfb94lq8	213	8	recurrent	recurrent	JJ
cord-264532-xfb94lq8	213	9	epidemics	epidemic	NNS
cord-264532-xfb94lq8	213	10	in	in	IN
cord-264532-xfb94lq8	213	11	humans	human	NNS
cord-264532-xfb94lq8	213	12	,	,	,
cord-264532-xfb94lq8	213	13	and	and	CC
cord-264532-xfb94lq8	213	14	these	these	DT
cord-264532-xfb94lq8	213	15	epidemics	epidemic	NNS
cord-264532-xfb94lq8	213	16	arise	arise	VBP
cord-264532-xfb94lq8	213	17	from	from	IN
cord-264532-xfb94lq8	213	18	various	various	JJ
cord-264532-xfb94lq8	213	19	forms	form	NNS
cord-264532-xfb94lq8	213	20	of	of	IN
cord-264532-xfb94lq8	213	21	viral	viral	JJ
cord-264532-xfb94lq8	213	22	evolution	evolution	NN
cord-264532-xfb94lq8	213	23	to	to	TO
cord-264532-xfb94lq8	213	24	escape	escape	VB
cord-264532-xfb94lq8	213	25	host	host	NN
cord-264532-xfb94lq8	213	26	immunity	immunity	NN
cord-264532-xfb94lq8	213	27	.	.	.
cord-264532-xfb94lq8	214	1	Flu	flu	NN
cord-264532-xfb94lq8	214	2	thus	thus	RB
cord-264532-xfb94lq8	214	3	exhibits	exhibit	VBZ
cord-264532-xfb94lq8	214	4	one	one	CD
cord-264532-xfb94lq8	214	5	of	of	IN
cord-264532-xfb94lq8	214	6	the	the	DT
cord-264532-xfb94lq8	214	7	main	main	JJ
cord-264532-xfb94lq8	214	8	features	feature	NNS
cord-264532-xfb94lq8	214	9	of	of	IN
cord-264532-xfb94lq8	214	10	the	the	DT
cord-264532-xfb94lq8	214	11	invasion	invasion	NN
cord-264532-xfb94lq8	214	12	threshold	threshold	NN
cord-264532-xfb94lq8	214	13	model	model	NN
cord-264532-xfb94lq8	214	14	.	.	.
cord-264532-xfb94lq8	215	1	There	there	EX
cord-264532-xfb94lq8	215	2	is	be	VBZ
cord-264532-xfb94lq8	215	3	also	also	RB
cord-264532-xfb94lq8	215	4	documented	document	VBN
cord-264532-xfb94lq8	215	5	variation	variation	NN
cord-264532-xfb94lq8	215	6	in	in	IN
cord-264532-xfb94lq8	215	7	virulence	virulence	NN
cord-264532-xfb94lq8	215	8	,	,	,
cord-264532-xfb94lq8	215	9	with	with	IN
cord-264532-xfb94lq8	215	10	the	the	DT
cord-264532-xfb94lq8	215	11	highest	high	JJS
cord-264532-xfb94lq8	215	12	virulence	virulence	NN
cord-264532-xfb94lq8	215	13	associated	associate	VBN
cord-264532-xfb94lq8	215	14	with	with	IN
cord-264532-xfb94lq8	215	15	some	some	DT
cord-264532-xfb94lq8	215	16	of	of	IN
cord-264532-xfb94lq8	215	17	the	the	DT
cord-264532-xfb94lq8	215	18	new	new	JJ
cord-264532-xfb94lq8	215	19	mutants	mutant	NNS
cord-264532-xfb94lq8	215	20	(	(	-LRB-
cord-264532-xfb94lq8	215	21	see	see	VB
cord-264532-xfb94lq8	215	22	below	below	RB
cord-264532-xfb94lq8	215	23	)	)	-RRB-
cord-264532-xfb94lq8	215	24	.	.	.
cord-264532-xfb94lq8	216	1	Flu	flu	NN
cord-264532-xfb94lq8	216	2	dynamics	dynamic	NNS
cord-264532-xfb94lq8	216	3	are	be	VBP
cord-264532-xfb94lq8	216	4	governed	govern	VBN
cord-264532-xfb94lq8	216	5	largely	largely	RB
cord-264532-xfb94lq8	216	6	by	by	IN
cord-264532-xfb94lq8	216	7	the	the	DT
cord-264532-xfb94lq8	216	8	interaction	interaction	NN
cord-264532-xfb94lq8	216	9	of	of	IN
cord-264532-xfb94lq8	216	10	host	host	NN
cord-264532-xfb94lq8	216	11	immunity	immunity	NN
cord-264532-xfb94lq8	216	12	and	and	CC
cord-264532-xfb94lq8	216	13	viral	viral	JJ
cord-264532-xfb94lq8	216	14	surface	surface	NN
cord-264532-xfb94lq8	216	15	antigens	antigen	NNS
cord-264532-xfb94lq8	216	16	as	as	RB
cord-264532-xfb94lq8	216	17	well	well	RB
cord-264532-xfb94lq8	216	18	as	as	IN
cord-264532-xfb94lq8	216	19	evolution	evolution	NN
cord-264532-xfb94lq8	216	20	of	of	IN
cord-264532-xfb94lq8	216	21	the	the	DT
cord-264532-xfb94lq8	216	22	viral	viral	JJ
cord-264532-xfb94lq8	216	23	antigens	antigen	NNS
cord-264532-xfb94lq8	216	24	(	(	-LRB-
cord-264532-xfb94lq8	216	25	Webster	Webster	NNP
cord-264532-xfb94lq8	216	26	et	et	NNP
cord-264532-xfb94lq8	216	27	al	al	NNP
cord-264532-xfb94lq8	216	28	.	.	NNP
cord-264532-xfb94lq8	216	29	1992	1992	CD
cord-264532-xfb94lq8	216	30	)	)	-RRB-
cord-264532-xfb94lq8	216	31	.	.	.
cord-264532-xfb94lq8	217	1	Influenza	influenza	NN
cord-264532-xfb94lq8	217	2	is	be	VBZ
cord-264532-xfb94lq8	217	3	typed	type	VBN
cord-264532-xfb94lq8	217	4	according	accord	VBG
cord-264532-xfb94lq8	217	5	to	to	IN
cord-264532-xfb94lq8	217	6	two	two	CD
cord-264532-xfb94lq8	217	7	viral	viral	JJ
cord-264532-xfb94lq8	217	8	antigens	antigen	NNS
cord-264532-xfb94lq8	217	9	,	,	,
cord-264532-xfb94lq8	217	10	the	the	DT
cord-264532-xfb94lq8	217	11	hemagglutinin	hemagglutinin	NN
cord-264532-xfb94lq8	217	12	(	(	-LRB-
cord-264532-xfb94lq8	217	13	'	'	``
cord-264532-xfb94lq8	217	14	H	h	NN
cord-264532-xfb94lq8	217	15	'	'	''
cord-264532-xfb94lq8	217	16	type	type	NN
cord-264532-xfb94lq8	217	17	)	)	-RRB-
cord-264532-xfb94lq8	217	18	and	and	CC
cord-264532-xfb94lq8	217	19	neuraminidase	neuraminidase	NN
cord-264532-xfb94lq8	217	20	(	(	-LRB-
cord-264532-xfb94lq8	217	21	'	'	``
cord-264532-xfb94lq8	217	22	N	n	NN
cord-264532-xfb94lq8	217	23	'	'	CC
cord-264532-xfb94lq8	217	24	type	type	NN
cord-264532-xfb94lq8	217	25	)	)	-RRB-
cord-264532-xfb94lq8	217	26	;	;	:
cord-264532-xfb94lq8	217	27	we	-PRON-	PRP
cord-264532-xfb94lq8	217	28	will	will	MD
cord-264532-xfb94lq8	217	29	limit	limit	VB
cord-264532-xfb94lq8	217	30	ourselves	-PRON-	PRP
cord-264532-xfb94lq8	217	31	here	here	RB
cord-264532-xfb94lq8	217	32	to	to	IN
cord-264532-xfb94lq8	217	33	the	the	DT
cord-264532-xfb94lq8	217	34	different	different	JJ
cord-264532-xfb94lq8	217	35	H	h	NN
cord-264532-xfb94lq8	217	36	types	type	NNS
cord-264532-xfb94lq8	217	37	.	.	.
cord-264532-xfb94lq8	218	1	There	there	EX
cord-264532-xfb94lq8	218	2	is	be	VBZ
cord-264532-xfb94lq8	218	3	a	a	DT
cord-264532-xfb94lq8	218	4	wide	wide	JJ
cord-264532-xfb94lq8	218	5	variety	variety	NN
cord-264532-xfb94lq8	218	6	of	of	IN
cord-264532-xfb94lq8	218	7	H	h	NN
cord-264532-xfb94lq8	218	8	types	type	NNS
cord-264532-xfb94lq8	218	9	in	in	IN
cord-264532-xfb94lq8	218	10	nature	nature	NN
cord-264532-xfb94lq8	218	11	,	,	,
cord-264532-xfb94lq8	218	12	due	due	JJ
cord-264532-xfb94lq8	218	13	partly	partly	RB
cord-264532-xfb94lq8	218	14	to	to	IN
cord-264532-xfb94lq8	218	15	the	the	DT
cord-264532-xfb94lq8	218	16	fact	fact	NN
cord-264532-xfb94lq8	218	17	that	that	IN
cord-264532-xfb94lq8	218	18	different	different	JJ
cord-264532-xfb94lq8	218	19	influenza	influenza	NN
cord-264532-xfb94lq8	218	20	A	a	DT
cord-264532-xfb94lq8	218	21	strains	strain	NNS
cord-264532-xfb94lq8	218	22	span	span	VBP
cord-264532-xfb94lq8	218	23	a	a	DT
cord-264532-xfb94lq8	218	24	wide	wide	JJ
cord-264532-xfb94lq8	218	25	variety	variety	NN
cord-264532-xfb94lq8	218	26	of	of	IN
cord-264532-xfb94lq8	218	27	warmblooded	warmblooded	JJ
cord-264532-xfb94lq8	218	28	hosts	host	NNS
cord-264532-xfb94lq8	218	29	.	.	.
cord-264532-xfb94lq8	219	1	Currently	currently	RB
cord-264532-xfb94lq8	219	2	,	,	,
cord-264532-xfb94lq8	219	3	H1	H1	NNP
cord-264532-xfb94lq8	219	4	and	and	CC
cord-264532-xfb94lq8	219	5	H3	H3	NNP
cord-264532-xfb94lq8	219	6	are	be	VBP
cord-264532-xfb94lq8	219	7	circulating	circulate	VBG
cord-264532-xfb94lq8	219	8	in	in	IN
cord-264532-xfb94lq8	219	9	humans	human	NNS
cord-264532-xfb94lq8	219	10	,	,	,
cord-264532-xfb94lq8	219	11	but	but	CC
cord-264532-xfb94lq8	219	12	H2	H2	NNP
cord-264532-xfb94lq8	219	13	was	be	VBD
cord-264532-xfb94lq8	219	14	abundant	abundant	JJ
cord-264532-xfb94lq8	219	15	in	in	IN
cord-264532-xfb94lq8	219	16	the	the	DT
cord-264532-xfb94lq8	219	17	past	past	NN
cord-264532-xfb94lq8	219	18	.	.	.
cord-264532-xfb94lq8	220	1	There	there	EX
cord-264532-xfb94lq8	220	2	are	be	VBP
cord-264532-xfb94lq8	220	3	two	two	CD
cord-264532-xfb94lq8	220	4	classes	class	NNS
cord-264532-xfb94lq8	220	5	of	of	IN
cord-264532-xfb94lq8	220	6	H	h	NN
cord-264532-xfb94lq8	220	7	mutants	mutant	NNS
cord-264532-xfb94lq8	220	8	that	that	WDT
cord-264532-xfb94lq8	220	9	invade	invade	VBP
cord-264532-xfb94lq8	220	10	humans	human	NNS
cord-264532-xfb94lq8	220	11	.	.	.
cord-264532-xfb94lq8	221	1	One	one	CD
cord-264532-xfb94lq8	221	2	class	class	NN
cord-264532-xfb94lq8	221	3	consists	consist	VBZ
cord-264532-xfb94lq8	221	4	of	of	IN
cord-264532-xfb94lq8	221	5	simple	simple	JJ
cord-264532-xfb94lq8	221	6	point	point	NN
cord-264532-xfb94lq8	221	7	mutants	mutant	NNS
cord-264532-xfb94lq8	221	8	of	of	IN
cord-264532-xfb94lq8	221	9	existing	exist	VBG
cord-264532-xfb94lq8	221	10	H	h	NN
cord-264532-xfb94lq8	221	11	types	type	NNS
cord-264532-xfb94lq8	221	12	(	(	-LRB-
cord-264532-xfb94lq8	221	13	referred	refer	VBN
cord-264532-xfb94lq8	221	14	to	to	IN
cord-264532-xfb94lq8	221	15	as	as	IN
cord-264532-xfb94lq8	221	16	subtypes	subtype	NNS
cord-264532-xfb94lq8	221	17	,	,	,
cord-264532-xfb94lq8	221	18	because	because	IN
cord-264532-xfb94lq8	221	19	of	of	IN
cord-264532-xfb94lq8	221	20	a	a	DT
cord-264532-xfb94lq8	221	21	process	process	NN
cord-264532-xfb94lq8	221	22	known	know	VBN
cord-264532-xfb94lq8	221	23	as	as	IN
cord-264532-xfb94lq8	221	24	'	'	``
cord-264532-xfb94lq8	221	25	antigenic	antigenic	JJ
cord-264532-xfb94lq8	221	26	drift	drift	NN
cord-264532-xfb94lq8	221	27	'	'	''
cord-264532-xfb94lq8	221	28	)	)	-RRB-
cord-264532-xfb94lq8	221	29	.	.	.
cord-264532-xfb94lq8	222	1	Most	Most	JJS
cord-264532-xfb94lq8	222	2	annual	annual	JJ
cord-264532-xfb94lq8	222	3	epidemics	epidemic	NNS
cord-264532-xfb94lq8	222	4	consist	consist	VBP
cord-264532-xfb94lq8	222	5	of	of	IN
cord-264532-xfb94lq8	222	6	these	these	DT
cord-264532-xfb94lq8	222	7	subtype	subtype	NN
cord-264532-xfb94lq8	222	8	mutants	mutant	NNS
cord-264532-xfb94lq8	222	9	,	,	,
cord-264532-xfb94lq8	222	10	and	and	CC
cord-264532-xfb94lq8	222	11	subtype	subtype	NN
cord-264532-xfb94lq8	222	12	evolution	evolution	NN
cord-264532-xfb94lq8	222	13	is	be	VBZ
cord-264532-xfb94lq8	222	14	substantial	substantial	JJ
cord-264532-xfb94lq8	222	15	enough	enough	RB
cord-264532-xfb94lq8	222	16	to	to	TO
cord-264532-xfb94lq8	222	17	largely	largely	RB
cord-264532-xfb94lq8	222	18	overcome	overcome	VB
cord-264532-xfb94lq8	222	19	immunity	immunity	NN
cord-264532-xfb94lq8	222	20	to	to	IN
cord-264532-xfb94lq8	222	21	the	the	DT
cord-264532-xfb94lq8	222	22	same	same	JJ
cord-264532-xfb94lq8	222	23	ancestral	ancestral	JJ
cord-264532-xfb94lq8	222	24	type	type	NN
cord-264532-xfb94lq8	222	25	from	from	IN
cord-264532-xfb94lq8	222	26	several	several	JJ
cord-264532-xfb94lq8	222	27	years	year	NNS
cord-264532-xfb94lq8	222	28	in	in	IN
cord-264532-xfb94lq8	222	29	the	the	DT
cord-264532-xfb94lq8	222	30	past	past	NN
cord-264532-xfb94lq8	223	1	(	(	-LRB-
cord-264532-xfb94lq8	223	2	Ferguson	Ferguson	NNP
cord-264532-xfb94lq8	223	3	et	et	NNP
cord-264532-xfb94lq8	223	4	al	al	NNP
cord-264532-xfb94lq8	223	5	.	.	NNP
cord-264532-xfb94lq8	223	6	2003	2003	CD
cord-264532-xfb94lq8	223	7	)	)	-RRB-
cord-264532-xfb94lq8	223	8	.	.	.
cord-264532-xfb94lq8	224	1	The	the	DT
cord-264532-xfb94lq8	224	2	other	other	JJ
cord-264532-xfb94lq8	224	3	class	class	NN
cord-264532-xfb94lq8	224	4	consists	consist	VBZ
cord-264532-xfb94lq8	224	5	of	of	IN
cord-264532-xfb94lq8	224	6	H	h	NN
cord-264532-xfb94lq8	224	7	types	type	NNS
cord-264532-xfb94lq8	224	8	introduced	introduce	VBN
cord-264532-xfb94lq8	224	9	from	from	IN
cord-264532-xfb94lq8	224	10	other	other	JJ
cord-264532-xfb94lq8	224	11	species	specie	NNS
cord-264532-xfb94lq8	224	12	(	(	-LRB-
cord-264532-xfb94lq8	224	13	a	a	DT
cord-264532-xfb94lq8	224	14	process	process	NN
cord-264532-xfb94lq8	224	15	of	of	IN
cord-264532-xfb94lq8	224	16	'	'	``
cord-264532-xfb94lq8	224	17	antigenic	antigenic	JJ
cord-264532-xfb94lq8	224	18	shift	shift	NN
cord-264532-xfb94lq8	224	19	'	'	''
cord-264532-xfb94lq8	224	20	)	)	-RRB-
cord-264532-xfb94lq8	224	21	.	.	.
cord-264532-xfb94lq8	225	1	Flu	flu	NN
cord-264532-xfb94lq8	225	2	virus	virus	NN
cord-264532-xfb94lq8	225	3	with	with	IN
cord-264532-xfb94lq8	225	4	novel	novel	NN
cord-264532-xfb94lq8	225	5	H	h	NN
cord-264532-xfb94lq8	225	6	types	type	NNS
cord-264532-xfb94lq8	225	7	have	have	VBP
cord-264532-xfb94lq8	225	8	a	a	DT
cord-264532-xfb94lq8	225	9	profound	profound	JJ
cord-264532-xfb94lq8	225	10	advantage	advantage	NN
cord-264532-xfb94lq8	225	11	because	because	IN
cord-264532-xfb94lq8	225	12	there	there	EX
cord-264532-xfb94lq8	225	13	is	be	VBZ
cord-264532-xfb94lq8	225	14	no	no	DT
cord-264532-xfb94lq8	225	15	prevailing	prevail	VBG
cord-264532-xfb94lq8	225	16	immunity	immunity	NN
cord-264532-xfb94lq8	225	17	in	in	IN
cord-264532-xfb94lq8	225	18	humans	human	NNS
cord-264532-xfb94lq8	225	19	against	against	IN
cord-264532-xfb94lq8	225	20	those	those	DT
cord-264532-xfb94lq8	225	21	types	type	NNS
cord-264532-xfb94lq8	225	22	.	.	.
cord-264532-xfb94lq8	226	1	Three	three	CD
cord-264532-xfb94lq8	226	2	world	world	NN
cord-264532-xfb94lq8	226	3	-	-	HYPH
cord-264532-xfb94lq8	226	4	wide	wide	JJ
cord-264532-xfb94lq8	226	5	flu	flu	NN
cord-264532-xfb94lq8	226	6	pandemics	pandemic	NNS
cord-264532-xfb94lq8	226	7	of	of	IN
cord-264532-xfb94lq8	226	8	the	the	DT
cord-264532-xfb94lq8	226	9	1900s	1900s	CD
cord-264532-xfb94lq8	226	10	were	be	VBD
cord-264532-xfb94lq8	226	11	notorious	notorious	JJ
cord-264532-xfb94lq8	226	12	for	for	IN
cord-264532-xfb94lq8	226	13	causing	cause	VBG
cord-264532-xfb94lq8	226	14	large	large	JJ
cord-264532-xfb94lq8	226	15	numbers	number	NNS
cord-264532-xfb94lq8	226	16	of	of	IN
cord-264532-xfb94lq8	226	17	infections	infection	NNS
cord-264532-xfb94lq8	226	18	and	and	CC
cord-264532-xfb94lq8	226	19	thus	thus	RB
cord-264532-xfb94lq8	226	20	large	large	JJ
cord-264532-xfb94lq8	226	21	numbers	number	NNS
cord-264532-xfb94lq8	226	22	of	of	IN
cord-264532-xfb94lq8	226	23	deaths	death	NNS
cord-264532-xfb94lq8	226	24	;	;	:
cord-264532-xfb94lq8	226	25	all	all	DT
cord-264532-xfb94lq8	226	26	were	be	VBD
cord-264532-xfb94lq8	226	27	due	due	JJ
cord-264532-xfb94lq8	226	28	to	to	IN
cord-264532-xfb94lq8	226	29	viruses	virus	NNS
cord-264532-xfb94lq8	226	30	that	that	WDT
cord-264532-xfb94lq8	226	31	had	have	VBD
cord-264532-xfb94lq8	226	32	acquired	acquire	VBN
cord-264532-xfb94lq8	226	33	H	h	NN
cord-264532-xfb94lq8	226	34	types	type	NNS
cord-264532-xfb94lq8	226	35	that	that	WDT
cord-264532-xfb94lq8	226	36	humans	human	NNS
cord-264532-xfb94lq8	226	37	had	have	VBD
cord-264532-xfb94lq8	226	38	not	not	RB
cord-264532-xfb94lq8	226	39	previously	previously	RB
cord-264532-xfb94lq8	226	40	experienced	experience	VBN
cord-264532-xfb94lq8	226	41	.	.	.
cord-264532-xfb94lq8	227	1	Not	not	RB
cord-264532-xfb94lq8	227	2	all	all	DT
cord-264532-xfb94lq8	227	3	viruses	virus	NNS
cord-264532-xfb94lq8	227	4	with	with	IN
cord-264532-xfb94lq8	227	5	novel	novel	NN
cord-264532-xfb94lq8	227	6	H	h	NN
cord-264532-xfb94lq8	227	7	types	type	NNS
cord-264532-xfb94lq8	227	8	readily	readily	RB
cord-264532-xfb94lq8	227	9	spread	spread	VBP
cord-264532-xfb94lq8	227	10	in	in	IN
cord-264532-xfb94lq8	227	11	humans	human	NNS
cord-264532-xfb94lq8	227	12	,	,	,
cord-264532-xfb94lq8	227	13	however	however	RB
cord-264532-xfb94lq8	227	14	,	,	,
cord-264532-xfb94lq8	227	15	and	and	CC
cord-264532-xfb94lq8	227	16	many	many	JJ
cord-264532-xfb94lq8	227	17	of	of	IN
cord-264532-xfb94lq8	227	18	these	these	DT
cord-264532-xfb94lq8	227	19	introductions	introduction	NNS
cord-264532-xfb94lq8	227	20	have	have	VBP
cord-264532-xfb94lq8	227	21	simply	simply	RB
cord-264532-xfb94lq8	227	22	died	die	VBN
cord-264532-xfb94lq8	227	23	out	out	RP
cord-264532-xfb94lq8	227	24	.	.	.
cord-264532-xfb94lq8	228	1	We	-PRON-	PRP
cord-264532-xfb94lq8	228	2	thus	thus	RB
cord-264532-xfb94lq8	228	3	have	have	VBP
cord-264532-xfb94lq8	228	4	a	a	DT
cord-264532-xfb94lq8	228	5	reasonable	reasonable	JJ
cord-264532-xfb94lq8	228	6	understanding	understanding	NN
cord-264532-xfb94lq8	228	7	of	of	IN
cord-264532-xfb94lq8	228	8	what	what	WP
cord-264532-xfb94lq8	228	9	types	type	NNS
cord-264532-xfb94lq8	228	10	of	of	IN
cord-264532-xfb94lq8	228	11	molecular	molecular	JJ
cord-264532-xfb94lq8	228	12	variation	variation	NN
cord-264532-xfb94lq8	228	13	enable	enable	VBP
cord-264532-xfb94lq8	228	14	a	a	DT
cord-264532-xfb94lq8	228	15	flu	flu	NN
cord-264532-xfb94lq8	228	16	virus	virus	NN
cord-264532-xfb94lq8	228	17	to	to	TO
cord-264532-xfb94lq8	228	18	escape	escape	VB
cord-264532-xfb94lq8	228	19	prevailing	prevail	VBG
cord-264532-xfb94lq8	228	20	immunity	immunity	NN
cord-264532-xfb94lq8	228	21	,	,	,
cord-264532-xfb94lq8	228	22	although	although	IN
cord-264532-xfb94lq8	228	23	this	this	DT
cord-264532-xfb94lq8	228	24	advantage	advantage	NN
cord-264532-xfb94lq8	228	25	by	by	IN
cord-264532-xfb94lq8	228	26	itself	-PRON-	PRP
cord-264532-xfb94lq8	228	27	is	be	VBZ
cord-264532-xfb94lq8	228	28	not	not	RB
cord-264532-xfb94lq8	228	29	sufficient	sufficient	JJ
cord-264532-xfb94lq8	228	30	to	to	TO
cord-264532-xfb94lq8	228	31	enable	enable	VB
cord-264532-xfb94lq8	228	32	spread	spread	VBN
cord-264532-xfb94lq8	228	33	in	in	IN
cord-264532-xfb94lq8	228	34	the	the	DT
cord-264532-xfb94lq8	228	35	human	human	JJ
cord-264532-xfb94lq8	228	36	population	population	NN
cord-264532-xfb94lq8	228	37	.	.	.
cord-264532-xfb94lq8	229	1	The	the	DT
cord-264532-xfb94lq8	229	2	virulence	virulence	NN
cord-264532-xfb94lq8	229	3	of	of	IN
cord-264532-xfb94lq8	229	4	influenza	influenza	NN
cord-264532-xfb94lq8	229	5	variants	variant	NNS
cord-264532-xfb94lq8	229	6	varies	vary	VBZ
cord-264532-xfb94lq8	229	7	somewhat	somewhat	RB
cord-264532-xfb94lq8	229	8	,	,	,
cord-264532-xfb94lq8	229	9	although	although	IN
cord-264532-xfb94lq8	229	10	it	-PRON-	PRP
cord-264532-xfb94lq8	229	11	is	be	VBZ
cord-264532-xfb94lq8	229	12	difficult	difficult	JJ
cord-264532-xfb94lq8	229	13	to	to	TO
cord-264532-xfb94lq8	229	14	apportion	apportion	VB
cord-264532-xfb94lq8	229	15	mortality	mortality	NN
cord-264532-xfb94lq8	229	16	between	between	IN
cord-264532-xfb94lq8	229	17	the	the	DT
cord-264532-xfb94lq8	229	18	virus	virus	NN
cord-264532-xfb94lq8	229	19	(	(	-LRB-
cord-264532-xfb94lq8	229	20	its	-PRON-	PRP$
cord-264532-xfb94lq8	229	21	intrinsic	intrinsic	JJ
cord-264532-xfb94lq8	229	22	virulence	virulence	NN
cord-264532-xfb94lq8	229	23	)	)	-RRB-
cord-264532-xfb94lq8	229	24	and	and	CC
cord-264532-xfb94lq8	229	25	the	the	DT
cord-264532-xfb94lq8	229	26	host	host	NN
cord-264532-xfb94lq8	229	27	(	(	-LRB-
cord-264532-xfb94lq8	229	28	whether	whether	IN
cord-264532-xfb94lq8	229	29	it	-PRON-	PRP
cord-264532-xfb94lq8	229	30	has	have	VBZ
cord-264532-xfb94lq8	229	31	any	any	DT
cord-264532-xfb94lq8	229	32	prevailing	prevail	VBG
cord-264532-xfb94lq8	229	33	immunity	immunity	NN
cord-264532-xfb94lq8	229	34	to	to	IN
cord-264532-xfb94lq8	229	35	the	the	DT
cord-264532-xfb94lq8	229	36	strain	strain	NN
cord-264532-xfb94lq8	229	37	)	)	-RRB-
cord-264532-xfb94lq8	229	38	.	.	.
cord-264532-xfb94lq8	230	1	The	the	DT
cord-264532-xfb94lq8	230	2	case	case	NN
cord-264532-xfb94lq8	230	3	mortality	mortality	NN
cord-264532-xfb94lq8	230	4	rate	rate	NN
cord-264532-xfb94lq8	230	5	of	of	IN
cord-264532-xfb94lq8	230	6	the	the	DT
cord-264532-xfb94lq8	230	7	H1N1	H1N1	NNP
cord-264532-xfb94lq8	230	8	1918	1918	CD
cord-264532-xfb94lq8	230	9	flu	flu	NN
cord-264532-xfb94lq8	230	10	that	that	WDT
cord-264532-xfb94lq8	230	11	killed	kill	VBD
cord-264532-xfb94lq8	230	12	20	20	CD
cord-264532-xfb94lq8	230	13	-	-	SYM
cord-264532-xfb94lq8	230	14	40	40	CD
cord-264532-xfb94lq8	230	15	million	million	CD
cord-264532-xfb94lq8	230	16	people	people	NNS
cord-264532-xfb94lq8	230	17	worldwide	worldwide	RB
cord-264532-xfb94lq8	230	18	was	be	VBD
cord-264532-xfb94lq8	230	19	reported	report	VBN
cord-264532-xfb94lq8	230	20	to	to	TO
cord-264532-xfb94lq8	230	21	be	be	VB
cord-264532-xfb94lq8	230	22	about	about	RB
cord-264532-xfb94lq8	230	23	1	1	CD
cord-264532-xfb94lq8	230	24	%	%	NN
cord-264532-xfb94lq8	230	25	,	,	,
cord-264532-xfb94lq8	230	26	somewhat	somewhat	RB
cord-264532-xfb94lq8	230	27	more	more	JJR
cord-264532-xfb94lq8	230	28	than	than	IN
cord-264532-xfb94lq8	230	29	a	a	DT
cord-264532-xfb94lq8	230	30	10-fold	10-fold	JJ
cord-264532-xfb94lq8	230	31	excess	excess	NN
cord-264532-xfb94lq8	230	32	of	of	IN
cord-264532-xfb94lq8	230	33	the	the	DT
cord-264532-xfb94lq8	230	34	typical	typical	JJ
cord-264532-xfb94lq8	230	35	mortality	mortality	NN
cord-264532-xfb94lq8	230	36	rate	rate	NN
cord-264532-xfb94lq8	230	37	per	per	IN
cord-264532-xfb94lq8	230	38	infection	infection	NN
cord-264532-xfb94lq8	230	39	of	of	IN
cord-264532-xfb94lq8	230	40	the	the	DT
cord-264532-xfb94lq8	230	41	viruses	virus	NNS
cord-264532-xfb94lq8	230	42	of	of	IN
cord-264532-xfb94lq8	230	43	today	today	NN
cord-264532-xfb94lq8	231	1	(	(	-LRB-
cord-264532-xfb94lq8	231	2	Taubenberger	Taubenberger	NNP
cord-264532-xfb94lq8	231	3	and	and	CC
cord-264532-xfb94lq8	231	4	Morens	Morens	NNP
cord-264532-xfb94lq8	231	5	2006	2006	CD
cord-264532-xfb94lq8	231	6	)	)	-RRB-
cord-264532-xfb94lq8	231	7	.	.	.
cord-264532-xfb94lq8	232	1	The	the	DT
cord-264532-xfb94lq8	232	2	virulence	virulence	NN
cord-264532-xfb94lq8	232	3	of	of	IN
cord-264532-xfb94lq8	232	4	this	this	DT
cord-264532-xfb94lq8	232	5	strain	strain	NN
cord-264532-xfb94lq8	232	6	appeared	appear	VBD
cord-264532-xfb94lq8	232	7	to	to	TO
cord-264532-xfb94lq8	232	8	wane	wane	VB
cord-264532-xfb94lq8	232	9	over	over	IN
cord-264532-xfb94lq8	232	10	a	a	DT
cord-264532-xfb94lq8	232	11	few	few	JJ
cord-264532-xfb94lq8	232	12	years	year	NNS
cord-264532-xfb94lq8	232	13	.	.	.
cord-264532-xfb94lq8	233	1	H1N1	H1N1	NNP
cord-264532-xfb94lq8	233	2	disappeared	disappear	VBD
cord-264532-xfb94lq8	233	3	in	in	IN
cord-264532-xfb94lq8	233	4	the	the	DT
cord-264532-xfb94lq8	233	5	1950s	1950	NNS
cord-264532-xfb94lq8	233	6	,	,	,
cord-264532-xfb94lq8	233	7	and	and	CC
cord-264532-xfb94lq8	233	8	its	-PRON-	PRP$
cord-264532-xfb94lq8	233	9	accidental	accidental	JJ
cord-264532-xfb94lq8	233	10	reintroduction	reintroduction	NN
cord-264532-xfb94lq8	233	11	in	in	IN
cord-264532-xfb94lq8	233	12	1977	1977	CD
cord-264532-xfb94lq8	233	13	to	to	IN
cord-264532-xfb94lq8	233	14	naive	naive	JJ
cord-264532-xfb94lq8	233	15	hosts	host	NNS
cord-264532-xfb94lq8	233	16	did	do	VBD
cord-264532-xfb94lq8	233	17	not	not	RB
cord-264532-xfb94lq8	233	18	lead	lead	VB
cord-264532-xfb94lq8	233	19	to	to	IN
cord-264532-xfb94lq8	233	20	the	the	DT
cord-264532-xfb94lq8	233	21	high	high	JJ
cord-264532-xfb94lq8	233	22	mortality	mortality	NN
cord-264532-xfb94lq8	233	23	rate	rate	NN
cord-264532-xfb94lq8	233	24	of	of	IN
cord-264532-xfb94lq8	233	25	1918	1918	CD
cord-264532-xfb94lq8	233	26	,	,	,
cord-264532-xfb94lq8	233	27	so	so	CC
cord-264532-xfb94lq8	233	28	it	-PRON-	PRP
cord-264532-xfb94lq8	233	29	appears	appear	VBZ
cord-264532-xfb94lq8	233	30	that	that	IN
cord-264532-xfb94lq8	233	31	the	the	DT
cord-264532-xfb94lq8	233	32	virulence	virulence	NN
cord-264532-xfb94lq8	233	33	per	per	FW
cord-264532-xfb94lq8	233	34	se	se	FW
cord-264532-xfb94lq8	233	35	evolved	evolve	VBD
cord-264532-xfb94lq8	233	36	downward	downward	RB
cord-264532-xfb94lq8	233	37	(	(	-LRB-
cord-264532-xfb94lq8	233	38	Kilbourne	Kilbourne	NNP
cord-264532-xfb94lq8	233	39	2006	2006	CD
cord-264532-xfb94lq8	233	40	)	)	-RRB-
cord-264532-xfb94lq8	233	41	.	.	.
cord-264532-xfb94lq8	234	1	Although	although	IN
cord-264532-xfb94lq8	234	2	mortality	mortality	NN
cord-264532-xfb94lq8	234	3	rates	rate	NNS
cord-264532-xfb94lq8	234	4	of	of	IN
cord-264532-xfb94lq8	234	5	the	the	DT
cord-264532-xfb94lq8	234	6	usual	usual	JJ
cord-264532-xfb94lq8	234	7	antigenic	antigenic	JJ
cord-264532-xfb94lq8	234	8	shift	shift	NN
cord-264532-xfb94lq8	234	9	strains	strain	NNS
cord-264532-xfb94lq8	234	10	remain	remain	VBP
cord-264532-xfb94lq8	234	11	relatively	relatively	RB
cord-264532-xfb94lq8	234	12	constant	constant	JJ
cord-264532-xfb94lq8	234	13	,	,	,
cord-264532-xfb94lq8	234	14	some	some	DT
cord-264532-xfb94lq8	234	15	high	high	JJ
cord-264532-xfb94lq8	234	16	virulence	virulence	NN
cord-264532-xfb94lq8	234	17	exceptions	exception	NNS
cord-264532-xfb94lq8	234	18	are	be	VBP
cord-264532-xfb94lq8	234	19	known	know	VBN
cord-264532-xfb94lq8	234	20	(	(	-LRB-
cord-264532-xfb94lq8	234	21	e.g.	e.g.	RB
cord-264532-xfb94lq8	234	22	,	,	,
cord-264532-xfb94lq8	234	23	an	an	DT
cord-264532-xfb94lq8	234	24	H3N2	H3N2	NNP
cord-264532-xfb94lq8	234	25	strain	strain	NN
cord-264532-xfb94lq8	234	26	from	from	IN
cord-264532-xfb94lq8	234	27	1997	1997	CD
cord-264532-xfb94lq8	234	28	;	;	.
cord-264532-xfb94lq8	235	1	O'Donnell	O'Donnell	NNP
cord-264532-xfb94lq8	235	2	et	et	NNP
cord-264532-xfb94lq8	235	3	al	al	NNP
cord-264532-xfb94lq8	235	4	.	.	NNP
cord-264532-xfb94lq8	235	5	2003	2003	CD
cord-264532-xfb94lq8	235	6	)	)	-RRB-
cord-264532-xfb94lq8	235	7	,	,	,
cord-264532-xfb94lq8	235	8	and	and	CC
cord-264532-xfb94lq8	236	1	there	there	EX
cord-264532-xfb94lq8	236	2	may	may	MD
cord-264532-xfb94lq8	236	3	well	well	RB
cord-264532-xfb94lq8	236	4	be	be	VB
cord-264532-xfb94lq8	236	5	many	many	JJ
cord-264532-xfb94lq8	236	6	low	low	JJ
cord-264532-xfb94lq8	236	7	-	-	HYPH
cord-264532-xfb94lq8	236	8	virulence	virulence	NN
cord-264532-xfb94lq8	236	9	variants	variant	NNS
cord-264532-xfb94lq8	236	10	that	that	WDT
cord-264532-xfb94lq8	236	11	go	go	VBP
cord-264532-xfb94lq8	236	12	unnoticed	unnoticed	JJ
cord-264532-xfb94lq8	236	13	.	.	.
cord-264532-xfb94lq8	237	1	However	however	RB
cord-264532-xfb94lq8	237	2	,	,	,
cord-264532-xfb94lq8	237	3	the	the	DT
cord-264532-xfb94lq8	237	4	H5N1	H5N1	NNP
cord-264532-xfb94lq8	237	5	strain	strain	NN
cord-264532-xfb94lq8	237	6	(	(	-LRB-
cord-264532-xfb94lq8	237	7	bird	bird	NN
cord-264532-xfb94lq8	237	8	flu	flu	NN
cord-264532-xfb94lq8	237	9	)	)	-RRB-
cord-264532-xfb94lq8	237	10	that	that	WDT
cord-264532-xfb94lq8	237	11	is	be	VBZ
cord-264532-xfb94lq8	237	12	circulating	circulate	VBG
cord-264532-xfb94lq8	237	13	widely	widely	RB
cord-264532-xfb94lq8	237	14	in	in	IN
cord-264532-xfb94lq8	237	15	birds	bird	NNS
cord-264532-xfb94lq8	238	1	has	have	VBZ
cord-264532-xfb94lq8	238	2	a	a	DT
cord-264532-xfb94lq8	238	3	case	case	NN
cord-264532-xfb94lq8	238	4	mortality	mortality	NN
cord-264532-xfb94lq8	238	5	rate	rate	NN
cord-264532-xfb94lq8	238	6	exceeding	exceed	VBG
cord-264532-xfb94lq8	238	7	50	50	CD
cord-264532-xfb94lq8	238	8	%	%	NN
cord-264532-xfb94lq8	238	9	in	in	IN
cord-264532-xfb94lq8	238	10	humans	human	NNS
cord-264532-xfb94lq8	238	11	,	,	,
cord-264532-xfb94lq8	238	12	far	far	RB
cord-264532-xfb94lq8	238	13	in	in	IN
cord-264532-xfb94lq8	238	14	excess	excess	NN
cord-264532-xfb94lq8	238	15	of	of	IN
cord-264532-xfb94lq8	238	16	the	the	DT
cord-264532-xfb94lq8	238	17	mortality	mortality	NN
cord-264532-xfb94lq8	238	18	rate	rate	NN
cord-264532-xfb94lq8	238	19	observed	observe	VBN
cord-264532-xfb94lq8	238	20	in	in	IN
cord-264532-xfb94lq8	238	21	any	any	DT
cord-264532-xfb94lq8	238	22	strain	strain	NN
cord-264532-xfb94lq8	238	23	that	that	WDT
cord-264532-xfb94lq8	238	24	established	establish	VBD
cord-264532-xfb94lq8	238	25	itself	-PRON-	PRP
cord-264532-xfb94lq8	238	26	in	in	IN
cord-264532-xfb94lq8	238	27	humans	human	NNS
cord-264532-xfb94lq8	238	28	(	(	-LRB-
cord-264532-xfb94lq8	238	29	Webster	Webster	NNP
cord-264532-xfb94lq8	238	30	et	et	NNP
cord-264532-xfb94lq8	238	31	al	al	NNP
cord-264532-xfb94lq8	238	32	.	.	.
cord-264532-xfb94lq8	238	33	2006	2006	CD
cord-264532-xfb94lq8	238	34	)	)	-RRB-
cord-264532-xfb94lq8	238	35	.	.	.
cord-264532-xfb94lq8	239	1	H5N1	H5N1	NNP
cord-264532-xfb94lq8	239	2	has	have	VBZ
cord-264532-xfb94lq8	239	3	not	not	RB
cord-264532-xfb94lq8	239	4	established	establish	VBN
cord-264532-xfb94lq8	239	5	itself	-PRON-	PRP
cord-264532-xfb94lq8	239	6	in	in	IN
cord-264532-xfb94lq8	239	7	the	the	DT
cord-264532-xfb94lq8	239	8	human	human	JJ
cord-264532-xfb94lq8	239	9	population	population	NN
cord-264532-xfb94lq8	239	10	,	,	,
cord-264532-xfb94lq8	239	11	but	but	CC
cord-264532-xfb94lq8	239	12	the	the	DT
cord-264532-xfb94lq8	239	13	obvious	obvious	JJ
cord-264532-xfb94lq8	239	14	fear	fear	NN
cord-264532-xfb94lq8	239	15	is	be	VBZ
cord-264532-xfb94lq8	239	16	that	that	IN
cord-264532-xfb94lq8	239	17	it	-PRON-	PRP
cord-264532-xfb94lq8	239	18	can	can	MD
cord-264532-xfb94lq8	239	19	do	do	VB
cord-264532-xfb94lq8	239	20	so	so	RB
cord-264532-xfb94lq8	239	21	and	and	CC
cord-264532-xfb94lq8	239	22	maintain	maintain	VB
cord-264532-xfb94lq8	239	23	its	-PRON-	PRP$
cord-264532-xfb94lq8	239	24	high	high	JJ
cord-264532-xfb94lq8	239	25	mortality	mortality	NN
cord-264532-xfb94lq8	239	26	rate	rate	NN
cord-264532-xfb94lq8	239	27	,	,	,
cord-264532-xfb94lq8	239	28	at	at	IN
cord-264532-xfb94lq8	239	29	least	least	JJS
cord-264532-xfb94lq8	239	30	during	during	IN
cord-264532-xfb94lq8	239	31	its	-PRON-	PRP$
cord-264532-xfb94lq8	239	32	first	first	JJ
cord-264532-xfb94lq8	239	33	round	round	NN
cord-264532-xfb94lq8	239	34	of	of	IN
cord-264532-xfb94lq8	239	35	global	global	JJ
cord-264532-xfb94lq8	239	36	spread	spread	NN
cord-264532-xfb94lq8	239	37	.	.	.
cord-264532-xfb94lq8	240	1	The	the	DT
cord-264532-xfb94lq8	240	2	invasion	invasion	NN
cord-264532-xfb94lq8	240	3	threshold	threshold	NN
cord-264532-xfb94lq8	240	4	perspective	perspective	NN
cord-264532-xfb94lq8	240	5	is	be	VBZ
cord-264532-xfb94lq8	240	6	thus	thus	RB
cord-264532-xfb94lq8	240	7	especially	especially	RB
cord-264532-xfb94lq8	240	8	relevant	relevant	JJ
cord-264532-xfb94lq8	240	9	here	here	RB
cord-264532-xfb94lq8	240	10	.	.	.
cord-264532-xfb94lq8	241	1	Ewald	Ewald	NNP
cord-264532-xfb94lq8	241	2	has	have	VBZ
cord-264532-xfb94lq8	241	3	used	use	VBN
cord-264532-xfb94lq8	241	4	the	the	DT
cord-264532-xfb94lq8	241	5	public	public	JJ
cord-264532-xfb94lq8	241	6	media	medium	NNS
cord-264532-xfb94lq8	241	7	to	to	TO
cord-264532-xfb94lq8	241	8	argue	argue	VB
cord-264532-xfb94lq8	241	9	that	that	IN
cord-264532-xfb94lq8	241	10	the	the	DT
cord-264532-xfb94lq8	241	11	virulence	virulence	NN
cord-264532-xfb94lq8	241	12	of	of	IN
cord-264532-xfb94lq8	241	13	H5N1	H5N1	NNP
cord-264532-xfb94lq8	241	14	will	will	MD
cord-264532-xfb94lq8	241	15	quickly	quickly	RB
cord-264532-xfb94lq8	241	16	evolve	evolve	VB
cord-264532-xfb94lq8	241	17	to	to	IN
cord-264532-xfb94lq8	241	18	low	low	JJ
cord-264532-xfb94lq8	241	19	levels	level	NNS
cord-264532-xfb94lq8	241	20	,	,	,
cord-264532-xfb94lq8	241	21	should	should	MD
cord-264532-xfb94lq8	241	22	it	-PRON-	PRP
cord-264532-xfb94lq8	241	23	invade	invade	VB
cord-264532-xfb94lq8	241	24	(	(	-LRB-
cord-264532-xfb94lq8	241	25	Orent	Orent	NNP
cord-264532-xfb94lq8	241	26	2005	2005	CD
cord-264532-xfb94lq8	241	27	)	)	-RRB-
cord-264532-xfb94lq8	241	28	;	;	:
cord-264532-xfb94lq8	241	29	this	this	DT
cord-264532-xfb94lq8	241	30	view	view	NN
cord-264532-xfb94lq8	241	31	has	have	VBZ
cord-264532-xfb94lq8	241	32	not	not	RB
cord-264532-xfb94lq8	241	33	been	be	VBN
cord-264532-xfb94lq8	241	34	widely	widely	RB
cord-264532-xfb94lq8	241	35	accepted	accept	VBN
cord-264532-xfb94lq8	241	36	(	(	-LRB-
cord-264532-xfb94lq8	241	37	Normile	Normile	NNP
cord-264532-xfb94lq8	241	38	2005	2005	CD
cord-264532-xfb94lq8	241	39	)	)	-RRB-
cord-264532-xfb94lq8	241	40	,	,	,
cord-264532-xfb94lq8	241	41	and	and	CC
cord-264532-xfb94lq8	241	42	the	the	DT
cord-264532-xfb94lq8	241	43	perspective	perspective	NN
cord-264532-xfb94lq8	241	44	of	of	IN
cord-264532-xfb94lq8	241	45	this	this	DT
cord-264532-xfb94lq8	241	46	paper	paper	NN
cord-264532-xfb94lq8	241	47	is	be	VBZ
cord-264532-xfb94lq8	241	48	that	that	IN
cord-264532-xfb94lq8	241	49	,	,	,
cord-264532-xfb94lq8	241	50	even	even	RB
cord-264532-xfb94lq8	241	51	if	if	IN
cord-264532-xfb94lq8	241	52	the	the	DT
cord-264532-xfb94lq8	241	53	H5N1	H5N1	NNP
cord-264532-xfb94lq8	241	54	optimum	optimum	NN
cord-264532-xfb94lq8	241	55	in	in	IN
cord-264532-xfb94lq8	241	56	humans	human	NNS
cord-264532-xfb94lq8	241	57	is	be	VBZ
cord-264532-xfb94lq8	241	58	low	low	JJ
cord-264532-xfb94lq8	241	59	virulence	virulence	NN
cord-264532-xfb94lq8	241	60	,	,	,
cord-264532-xfb94lq8	241	61	the	the	DT
cord-264532-xfb94lq8	241	62	epidemic	epidemic	NN
cord-264532-xfb94lq8	241	63	could	could	MD
cord-264532-xfb94lq8	241	64	have	have	VB
cord-264532-xfb94lq8	241	65	devastating	devastating	JJ
cord-264532-xfb94lq8	241	66	effects	effect	NNS
cord-264532-xfb94lq8	241	67	before	before	IN
cord-264532-xfb94lq8	241	68	it	-PRON-	PRP
cord-264532-xfb94lq8	241	69	neared	near	VBD
cord-264532-xfb94lq8	241	70	the	the	DT
cord-264532-xfb94lq8	241	71	viral	viral	JJ
cord-264532-xfb94lq8	241	72	optimum	optimum	NN
cord-264532-xfb94lq8	241	73	.	.	.
cord-264532-xfb94lq8	242	1	Feline	feline	JJ
cord-264532-xfb94lq8	242	2	calicivirus	calicivirus	NNP
cord-264532-xfb94lq8	242	3	(	(	-LRB-
cord-264532-xfb94lq8	242	4	FCV	FCV	NNP
cord-264532-xfb94lq8	242	5	)	)	-RRB-
cord-264532-xfb94lq8	242	6	is	be	VBZ
cord-264532-xfb94lq8	242	7	an	an	DT
cord-264532-xfb94lq8	242	8	RNA	RNA	NNP
cord-264532-xfb94lq8	242	9	virus	virus	NN
cord-264532-xfb94lq8	242	10	of	of	IN
cord-264532-xfb94lq8	242	11	domestic	domestic	JJ
cord-264532-xfb94lq8	242	12	cats	cat	NNS
cord-264532-xfb94lq8	242	13	.	.	.
cord-264532-xfb94lq8	243	1	A	a	DT
cord-264532-xfb94lq8	243	2	large	large	JJ
cord-264532-xfb94lq8	243	3	variety	variety	NN
cord-264532-xfb94lq8	243	4	of	of	IN
cord-264532-xfb94lq8	243	5	FCV	FCV	NNP
cord-264532-xfb94lq8	243	6	strains	strain	NNS
cord-264532-xfb94lq8	243	7	is	be	VBZ
cord-264532-xfb94lq8	243	8	known	know	VBN
cord-264532-xfb94lq8	243	9	to	to	TO
cord-264532-xfb94lq8	243	10	circulate	circulate	VB
cord-264532-xfb94lq8	243	11	concurrently	concurrently	RB
cord-264532-xfb94lq8	243	12	,	,	,
cord-264532-xfb94lq8	243	13	with	with	IN
cord-264532-xfb94lq8	243	14	sequence	sequence	NN
cord-264532-xfb94lq8	243	15	divergence	divergence	NN
cord-264532-xfb94lq8	243	16	in	in	IN
cord-264532-xfb94lq8	243	17	the	the	DT
cord-264532-xfb94lq8	243	18	variable	variable	JJ
cord-264532-xfb94lq8	243	19	region	region	NN
cord-264532-xfb94lq8	243	20	of	of	IN
cord-264532-xfb94lq8	243	21	the	the	DT
cord-264532-xfb94lq8	243	22	capsid	capsid	JJ
cord-264532-xfb94lq8	243	23	protein	protein	NN
cord-264532-xfb94lq8	243	24	gene	gene	NN
cord-264532-xfb94lq8	243	25	ranging	range	VBG
cord-264532-xfb94lq8	243	26	as	as	RB
cord-264532-xfb94lq8	243	27	much	much	JJ
cord-264532-xfb94lq8	243	28	as	as	IN
cord-264532-xfb94lq8	243	29	50	50	CD
cord-264532-xfb94lq8	243	30	%	%	NN
cord-264532-xfb94lq8	243	31	between	between	IN
cord-264532-xfb94lq8	243	32	strains	strain	NNS
cord-264532-xfb94lq8	243	33	)	)	-RRB-
cord-264532-xfb94lq8	243	34	.	.	.
cord-264532-xfb94lq8	244	1	Virulence	virulence	NN
cord-264532-xfb94lq8	244	2	varies	vary	VBZ
cord-264532-xfb94lq8	244	3	among	among	IN
cord-264532-xfb94lq8	244	4	isolates	isolate	NNS
cord-264532-xfb94lq8	244	5	,	,	,
cord-264532-xfb94lq8	244	6	from	from	IN
cord-264532-xfb94lq8	244	7	asymptomatic	asymptomatic	JJ
cord-264532-xfb94lq8	244	8	to	to	IN
cord-264532-xfb94lq8	244	9	highly	highly	RB
cord-264532-xfb94lq8	244	10	virulent	virulent	JJ
cord-264532-xfb94lq8	244	11	,	,	,
cord-264532-xfb94lq8	244	12	the	the	DT
cord-264532-xfb94lq8	244	13	latter	latter	JJ
cord-264532-xfb94lq8	244	14	being	be	VBG
cord-264532-xfb94lq8	244	15	as	as	RB
cord-264532-xfb94lq8	244	16	high	high	JJ
cord-264532-xfb94lq8	244	17	as	as	IN
cord-264532-xfb94lq8	244	18	50	50	CD
cord-264532-xfb94lq8	244	19	%	%	NN
cord-264532-xfb94lq8	244	20	mortality	mortality	NN
cord-264532-xfb94lq8	244	21	(	(	-LRB-
cord-264532-xfb94lq8	244	22	termed	term	VBN
cord-264532-xfb94lq8	244	23	VSD	VSD	NNP
cord-264532-xfb94lq8	244	24	strains	strain	NNS
cord-264532-xfb94lq8	244	25	,	,	,
cord-264532-xfb94lq8	244	26	for	for	IN
cord-264532-xfb94lq8	244	27	'	'	``
cord-264532-xfb94lq8	244	28	virulent	virulent	JJ
cord-264532-xfb94lq8	244	29	systemic	systemic	JJ
cord-264532-xfb94lq8	244	30	disease	disease	NN
cord-264532-xfb94lq8	244	31	'	'	''
cord-264532-xfb94lq8	244	32	)	)	-RRB-
cord-264532-xfb94lq8	244	33	.	.	.
cord-264532-xfb94lq8	245	1	Multiple	multiple	JJ
cord-264532-xfb94lq8	245	2	strains	strain	NNS
cord-264532-xfb94lq8	245	3	often	often	RB
cord-264532-xfb94lq8	245	4	circulate	circulate	VBP
cord-264532-xfb94lq8	245	5	within	within	IN
cord-264532-xfb94lq8	245	6	a	a	DT
cord-264532-xfb94lq8	245	7	local	local	JJ
cord-264532-xfb94lq8	245	8	cat	cat	NN
cord-264532-xfb94lq8	245	9	population	population	NN
cord-264532-xfb94lq8	245	10	.	.	.
cord-264532-xfb94lq8	246	1	Vaccines	vaccine	NNS
cord-264532-xfb94lq8	246	2	are	be	VBP
cord-264532-xfb94lq8	246	3	available	available	JJ
cord-264532-xfb94lq8	246	4	,	,	,
cord-264532-xfb94lq8	246	5	but	but	CC
cord-264532-xfb94lq8	246	6	vaccination	vaccination	NN
cord-264532-xfb94lq8	246	7	neither	neither	CC
cord-264532-xfb94lq8	246	8	prevents	prevent	VBZ
cord-264532-xfb94lq8	246	9	viral	viral	JJ
cord-264532-xfb94lq8	246	10	infection	infection	NN
cord-264532-xfb94lq8	246	11	nor	nor	CC
cord-264532-xfb94lq8	246	12	prevents	prevent	VBZ
cord-264532-xfb94lq8	246	13	viral	viral	JJ
cord-264532-xfb94lq8	246	14	replication	replication	NN
cord-264532-xfb94lq8	246	15	within	within	IN
cord-264532-xfb94lq8	246	16	a	a	DT
cord-264532-xfb94lq8	246	17	cat	cat	NN
cord-264532-xfb94lq8	246	18	,	,	,
cord-264532-xfb94lq8	246	19	so	so	CC
cord-264532-xfb94lq8	246	20	it	-PRON-	PRP
cord-264532-xfb94lq8	246	21	appears	appear	VBZ
cord-264532-xfb94lq8	246	22	that	that	IN
cord-264532-xfb94lq8	246	23	cross	cross	NN
cord-264532-xfb94lq8	246	24	immunity	immunity	NN
cord-264532-xfb94lq8	246	25	among	among	IN
cord-264532-xfb94lq8	246	26	strains	strain	NNS
cord-264532-xfb94lq8	246	27	is	be	VBZ
cord-264532-xfb94lq8	246	28	only	only	RB
cord-264532-xfb94lq8	246	29	partial	partial	JJ
cord-264532-xfb94lq8	246	30	.	.	.
cord-264532-xfb94lq8	247	1	Consistent	consistent	JJ
cord-264532-xfb94lq8	247	2	with	with	IN
cord-264532-xfb94lq8	247	3	the	the	DT
cord-264532-xfb94lq8	247	4	invasion	invasion	NN
cord-264532-xfb94lq8	247	5	threshold	threshold	NN
cord-264532-xfb94lq8	247	6	model	model	NN
cord-264532-xfb94lq8	247	7	,	,	,
cord-264532-xfb94lq8	247	8	nearly	nearly	RB
cord-264532-xfb94lq8	247	9	a	a	DT
cord-264532-xfb94lq8	247	10	dozen	dozen	NN
cord-264532-xfb94lq8	247	11	separate	separate	JJ
cord-264532-xfb94lq8	247	12	outbreaks	outbreak	NNS
cord-264532-xfb94lq8	247	13	of	of	IN
cord-264532-xfb94lq8	247	14	VSD	VSD	NNP
cord-264532-xfb94lq8	247	15	have	have	VBP
cord-264532-xfb94lq8	247	16	been	be	VBN
cord-264532-xfb94lq8	247	17	reported	report	VBN
cord-264532-xfb94lq8	247	18	.	.	.
cord-264532-xfb94lq8	248	1	When	when	WRB
cord-264532-xfb94lq8	248	2	subjected	subject	VBN
cord-264532-xfb94lq8	248	3	to	to	IN
cord-264532-xfb94lq8	248	4	a	a	DT
cord-264532-xfb94lq8	248	5	phylogenetic	phylogenetic	JJ
cord-264532-xfb94lq8	248	6	analysis	analysis	NN
cord-264532-xfb94lq8	248	7	,	,	,
cord-264532-xfb94lq8	248	8	the	the	DT
cord-264532-xfb94lq8	248	9	different	different	JJ
cord-264532-xfb94lq8	248	10	VSD	vsd	NN
cord-264532-xfb94lq8	248	11	strains	strain	NNS
cord-264532-xfb94lq8	248	12	appear	appear	VBP
cord-264532-xfb94lq8	248	13	to	to	TO
cord-264532-xfb94lq8	248	14	have	have	VB
cord-264532-xfb94lq8	248	15	independent	independent	JJ
cord-264532-xfb94lq8	248	16	origins	origin	NNS
cord-264532-xfb94lq8	248	17	from	from	IN
cord-264532-xfb94lq8	248	18	less	less	RBR
cord-264532-xfb94lq8	248	19	virulent	virulent	JJ
cord-264532-xfb94lq8	248	20	ancestors	ancestor	NNS
cord-264532-xfb94lq8	248	21	.	.	.
cord-264532-xfb94lq8	249	1	Additionally	additionally	RB
cord-264532-xfb94lq8	249	2	,	,	,
cord-264532-xfb94lq8	249	3	the	the	DT
cord-264532-xfb94lq8	249	4	VSD	VSD	NNP
cord-264532-xfb94lq8	249	5	outbreaks	outbreak	NNS
cord-264532-xfb94lq8	249	6	appear	appear	VBP
cord-264532-xfb94lq8	249	7	to	to	TO
cord-264532-xfb94lq8	249	8	have	have	VB
cord-264532-xfb94lq8	249	9	been	be	VBN
cord-264532-xfb94lq8	249	10	terminated	terminate	VBN
cord-264532-xfb94lq8	249	11	by	by	IN
cord-264532-xfb94lq8	249	12	viral	viral	JJ
cord-264532-xfb94lq8	249	13	extinctions	extinction	NNS
cord-264532-xfb94lq8	249	14	,	,	,
cord-264532-xfb94lq8	249	15	possibly	possibly	RB
cord-264532-xfb94lq8	249	16	from	from	IN
cord-264532-xfb94lq8	249	17	reducing	reduce	VBG
cord-264532-xfb94lq8	249	18	the	the	DT
cord-264532-xfb94lq8	249	19	local	local	JJ
cord-264532-xfb94lq8	249	20	cat	cat	NN
cord-264532-xfb94lq8	249	21	density	density	NN
cord-264532-xfb94lq8	249	22	)	)	-RRB-
cord-264532-xfb94lq8	249	23	.	.	.
cord-264532-xfb94lq8	250	1	The	the	DT
cord-264532-xfb94lq8	250	2	die	die	NN
cord-264532-xfb94lq8	250	3	-	-	HYPH
cord-264532-xfb94lq8	250	4	outs	out	NNS
cord-264532-xfb94lq8	250	5	could	could	MD
cord-264532-xfb94lq8	250	6	be	be	VB
cord-264532-xfb94lq8	250	7	interpreted	interpret	VBN
cord-264532-xfb94lq8	250	8	as	as	IN
cord-264532-xfb94lq8	250	9	the	the	DT
cord-264532-xfb94lq8	250	10	failure	failure	NN
cord-264532-xfb94lq8	250	11	to	to	TO
cord-264532-xfb94lq8	250	12	evolve	evolve	VB
cord-264532-xfb94lq8	250	13	optimal	optimal	JJ
cord-264532-xfb94lq8	250	14	virulence	virulence	NN
cord-264532-xfb94lq8	250	15	(	(	-LRB-
cord-264532-xfb94lq8	250	16	consistent	consistent	JJ
cord-264532-xfb94lq8	250	17	with	with	IN
cord-264532-xfb94lq8	250	18	the	the	DT
cord-264532-xfb94lq8	250	19	invasion	invasion	NN
cord-264532-xfb94lq8	250	20	threshold	threshold	NN
cord-264532-xfb94lq8	250	21	model	model	NN
cord-264532-xfb94lq8	250	22	)	)	-RRB-
cord-264532-xfb94lq8	250	23	,	,	,
cord-264532-xfb94lq8	250	24	or	or	CC
cord-264532-xfb94lq8	250	25	as	as	IN
cord-264532-xfb94lq8	250	26	evidence	evidence	NN
cord-264532-xfb94lq8	250	27	that	that	IN
cord-264532-xfb94lq8	250	28	near	near	JJ
cord-264532-xfb94lq8	250	29	-	-	HYPH
cord-264532-xfb94lq8	250	30	optimal	optimal	JJ
cord-264532-xfb94lq8	250	31	strains	strain	NNS
cord-264532-xfb94lq8	250	32	are	be	VBP
cord-264532-xfb94lq8	250	33	replacing	replace	VBG
cord-264532-xfb94lq8	250	34	the	the	DT
cord-264532-xfb94lq8	250	35	VSD	VSD	NNP
cord-264532-xfb94lq8	250	36	strains	strain	NNS
cord-264532-xfb94lq8	250	37	as	as	IN
cord-264532-xfb94lq8	250	38	host	host	NN
cord-264532-xfb94lq8	250	39	density	density	NN
cord-264532-xfb94lq8	250	40	wanes	wane	VBZ
cord-264532-xfb94lq8	250	41	(	(	-LRB-
cord-264532-xfb94lq8	250	42	consistent	consistent	JJ
cord-264532-xfb94lq8	250	43	with	with	IN
cord-264532-xfb94lq8	250	44	the	the	DT
cord-264532-xfb94lq8	250	45	Lenski	Lenski	NNP
cord-264532-xfb94lq8	250	46	-	-	HYPH
cord-264532-xfb94lq8	250	47	May	May	NNP
cord-264532-xfb94lq8	250	48	model	model	NN
cord-264532-xfb94lq8	250	49	)	)	-RRB-
cord-264532-xfb94lq8	250	50	.	.	.
cord-264532-xfb94lq8	251	1	Most	Most	JJS
cord-264532-xfb94lq8	251	2	agricultural	agricultural	JJ
cord-264532-xfb94lq8	251	3	animals	animal	NNS
cord-264532-xfb94lq8	251	4	used	use	VBN
cord-264532-xfb94lq8	251	5	as	as	IN
cord-264532-xfb94lq8	251	6	food	food	NN
cord-264532-xfb94lq8	251	7	sources	source	NNS
cord-264532-xfb94lq8	251	8	,	,	,
cord-264532-xfb94lq8	251	9	such	such	JJ
cord-264532-xfb94lq8	251	10	as	as	IN
cord-264532-xfb94lq8	251	11	pigs	pig	NNS
cord-264532-xfb94lq8	251	12	,	,	,
cord-264532-xfb94lq8	251	13	chickens	chicken	NNS
cord-264532-xfb94lq8	251	14	,	,	,
cord-264532-xfb94lq8	251	15	and	and	CC
cord-264532-xfb94lq8	251	16	cattle	cattle	NNS
cord-264532-xfb94lq8	251	17	are	be	VBP
cord-264532-xfb94lq8	251	18	housed	house	VBN
cord-264532-xfb94lq8	251	19	at	at	IN
cord-264532-xfb94lq8	251	20	high	high	JJ
cord-264532-xfb94lq8	251	21	densities	density	NNS
cord-264532-xfb94lq8	251	22	and	and	CC
cord-264532-xfb94lq8	251	23	in	in	IN
cord-264532-xfb94lq8	251	24	conditions	condition	NNS
cord-264532-xfb94lq8	251	25	of	of	IN
cord-264532-xfb94lq8	251	26	stress	stress	NN
cord-264532-xfb94lq8	251	27	that	that	WDT
cord-264532-xfb94lq8	251	28	facilitate	facilitate	VBP
cord-264532-xfb94lq8	251	29	the	the	DT
cord-264532-xfb94lq8	251	30	spread	spread	NN
cord-264532-xfb94lq8	251	31	of	of	IN
cord-264532-xfb94lq8	251	32	infectious	infectious	JJ
cord-264532-xfb94lq8	251	33	diseases	disease	NNS
cord-264532-xfb94lq8	251	34	.	.	.
cord-264532-xfb94lq8	252	1	Even	even	RB
cord-264532-xfb94lq8	252	2	if	if	IN
cord-264532-xfb94lq8	252	3	a	a	DT
cord-264532-xfb94lq8	252	4	farm	farm	NN
cord-264532-xfb94lq8	252	5	's	's	POS
cord-264532-xfb94lq8	252	6	livestock	livestock	NN
cord-264532-xfb94lq8	252	7	is	be	VBZ
cord-264532-xfb94lq8	252	8	wiped	wipe	VBN
cord-264532-xfb94lq8	252	9	out	out	RP
cord-264532-xfb94lq8	252	10	by	by	IN
cord-264532-xfb94lq8	252	11	an	an	DT
cord-264532-xfb94lq8	252	12	infection	infection	NN
cord-264532-xfb94lq8	252	13	,	,	,
cord-264532-xfb94lq8	252	14	new	new	JJ
cord-264532-xfb94lq8	252	15	animals	animal	NNS
cord-264532-xfb94lq8	252	16	may	may	MD
cord-264532-xfb94lq8	252	17	be	be	VB
cord-264532-xfb94lq8	252	18	brought	bring	VBN
cord-264532-xfb94lq8	252	19	in	in	RP
cord-264532-xfb94lq8	252	20	and	and	CC
cord-264532-xfb94lq8	252	21	maintained	maintain	VBN
cord-264532-xfb94lq8	252	22	at	at	IN
cord-264532-xfb94lq8	252	23	high	high	JJ
cord-264532-xfb94lq8	252	24	densities	density	NNS
cord-264532-xfb94lq8	252	25	again	again	RB
cord-264532-xfb94lq8	252	26	.	.	.
cord-264532-xfb94lq8	253	1	This	this	DT
cord-264532-xfb94lq8	253	2	artificial	artificial	JJ
cord-264532-xfb94lq8	253	3	maintenance	maintenance	NN
cord-264532-xfb94lq8	253	4	of	of	IN
cord-264532-xfb94lq8	253	5	high	high	JJ
cord-264532-xfb94lq8	253	6	host	host	NN
cord-264532-xfb94lq8	253	7	density	density	NN
cord-264532-xfb94lq8	253	8	is	be	VBZ
cord-264532-xfb94lq8	253	9	in	in	IN
cord-264532-xfb94lq8	253	10	contrast	contrast	NN
cord-264532-xfb94lq8	253	11	to	to	IN
cord-264532-xfb94lq8	253	12	the	the	DT
cord-264532-xfb94lq8	253	13	usual	usual	JJ
cord-264532-xfb94lq8	253	14	pattern	pattern	NN
cord-264532-xfb94lq8	253	15	in	in	IN
cord-264532-xfb94lq8	253	16	epidemiological	epidemiological	JJ
cord-264532-xfb94lq8	253	17	models	model	NNS
cord-264532-xfb94lq8	253	18	that	that	WDT
cord-264532-xfb94lq8	253	19	parasites	parasite	NNS
cord-264532-xfb94lq8	253	20	regulate	regulate	VBP
cord-264532-xfb94lq8	253	21	the	the	DT
cord-264532-xfb94lq8	253	22	densities	density	NNS
cord-264532-xfb94lq8	253	23	of	of	IN
cord-264532-xfb94lq8	253	24	their	-PRON-	PRP$
cord-264532-xfb94lq8	253	25	hosts	host	NNS
cord-264532-xfb94lq8	253	26	.	.	.
cord-264532-xfb94lq8	254	1	These	these	DT
cord-264532-xfb94lq8	254	2	enforced	enforce	VBD
cord-264532-xfb94lq8	254	3	high	high	JJ
cord-264532-xfb94lq8	254	4	host	host	NN
cord-264532-xfb94lq8	254	5	densities	density	NNS
cord-264532-xfb94lq8	254	6	have	have	VBP
cord-264532-xfb94lq8	254	7	been	be	VBN
cord-264532-xfb94lq8	254	8	suggested	suggest	VBN
cord-264532-xfb94lq8	254	9	to	to	TO
cord-264532-xfb94lq8	254	10	be	be	VB
cord-264532-xfb94lq8	254	11	especially	especially	RB
cord-264532-xfb94lq8	254	12	prone	prone	JJ
cord-264532-xfb94lq8	254	13	to	to	IN
cord-264532-xfb94lq8	254	14	the	the	DT
cord-264532-xfb94lq8	254	15	evolution	evolution	NN
cord-264532-xfb94lq8	254	16	of	of	IN
cord-264532-xfb94lq8	254	17	highly	highly	RB
cord-264532-xfb94lq8	254	18	virulent	virulent	JJ
cord-264532-xfb94lq8	254	19	parasites	parasite	NNS
cord-264532-xfb94lq8	254	20	,	,	,
cord-264532-xfb94lq8	254	21	because	because	IN
cord-264532-xfb94lq8	254	22	virulent	virulent	JJ
cord-264532-xfb94lq8	254	23	parasites	parasite	NNS
cord-264532-xfb94lq8	254	24	do	do	VBP
cord-264532-xfb94lq8	254	25	not	not	RB
cord-264532-xfb94lq8	254	26	die	die	VB
cord-264532-xfb94lq8	254	27	out	out	RP
cord-264532-xfb94lq8	254	28	even	even	RB
cord-264532-xfb94lq8	254	29	when	when	WRB
cord-264532-xfb94lq8	254	30	their	-PRON-	PRP$
cord-264532-xfb94lq8	254	31	hosts	host	NNS
cord-264532-xfb94lq8	254	32	do	do	VBP
cord-264532-xfb94lq8	254	33	.	.	.
cord-264532-xfb94lq8	255	1	Although	although	IN
cord-264532-xfb94lq8	255	2	cleanups	cleanup	NNS
cord-264532-xfb94lq8	255	3	following	follow	VBG
cord-264532-xfb94lq8	255	4	an	an	DT
cord-264532-xfb94lq8	255	5	outbreak	outbreak	NN
cord-264532-xfb94lq8	255	6	are	be	VBP
cord-264532-xfb94lq8	255	7	usually	usually	RB
cord-264532-xfb94lq8	255	8	attempted	attempt	VBN
cord-264532-xfb94lq8	255	9	,	,	,
cord-264532-xfb94lq8	255	10	the	the	DT
cord-264532-xfb94lq8	255	11	same	same	JJ
cord-264532-xfb94lq8	255	12	buildings	building	NNS
cord-264532-xfb94lq8	255	13	and	and	CC
cord-264532-xfb94lq8	255	14	grounds	ground	NNS
cord-264532-xfb94lq8	255	15	are	be	VBP
cord-264532-xfb94lq8	255	16	often	often	RB
cord-264532-xfb94lq8	255	17	used	use	VBN
cord-264532-xfb94lq8	255	18	for	for	IN
cord-264532-xfb94lq8	255	19	restocking	restocking	NN
cord-264532-xfb94lq8	255	20	,	,	,
cord-264532-xfb94lq8	255	21	allowing	allow	VBG
cord-264532-xfb94lq8	255	22	any	any	DT
cord-264532-xfb94lq8	255	23	remaining	remain	VBG
cord-264532-xfb94lq8	255	24	environmental	environmental	JJ
cord-264532-xfb94lq8	255	25	source	source	NN
cord-264532-xfb94lq8	255	26	of	of	IN
cord-264532-xfb94lq8	255	27	parasite	parasite	NN
cord-264532-xfb94lq8	255	28	to	to	TO
cord-264532-xfb94lq8	255	29	reinvade	reinvade	VB
cord-264532-xfb94lq8	255	30	.	.	.
cord-264532-xfb94lq8	256	1	The	the	DT
cord-264532-xfb94lq8	256	2	difficulty	difficulty	NN
cord-264532-xfb94lq8	256	3	of	of	IN
cord-264532-xfb94lq8	256	4	applying	apply	VBG
cord-264532-xfb94lq8	256	5	equilibrium	equilibrium	NN
cord-264532-xfb94lq8	256	6	theory	theory	NN
cord-264532-xfb94lq8	256	7	to	to	IN
cord-264532-xfb94lq8	256	8	these	these	DT
cord-264532-xfb94lq8	256	9	situations	situation	NNS
cord-264532-xfb94lq8	256	10	is	be	VBZ
cord-264532-xfb94lq8	256	11	illustrated	illustrate	VBN
cord-264532-xfb94lq8	256	12	by	by	IN
cord-264532-xfb94lq8	256	13	the	the	DT
cord-264532-xfb94lq8	256	14	pig	pig	NN
cord-264532-xfb94lq8	256	15	virus	virus	NN
cord-264532-xfb94lq8	256	16	transmissible	transmissible	JJ
cord-264532-xfb94lq8	256	17	gastroenteritis	gastroenteritis	NN
cord-264532-xfb94lq8	256	18	coronavirus	coronavirus	NN
cord-264532-xfb94lq8	256	19	(	(	-LRB-
cord-264532-xfb94lq8	256	20	TGEV	TGEV	NNP
cord-264532-xfb94lq8	256	21	)	)	-RRB-
cord-264532-xfb94lq8	256	22	.	.	.
cord-264532-xfb94lq8	257	1	Historically	historically	RB
cord-264532-xfb94lq8	257	2	,	,	,
cord-264532-xfb94lq8	257	3	a	a	DT
cord-264532-xfb94lq8	257	4	highly	highly	RB
cord-264532-xfb94lq8	257	5	lethal	lethal	JJ
cord-264532-xfb94lq8	257	6	gut	gut	NN
cord-264532-xfb94lq8	257	7	infection	infection	NN
cord-264532-xfb94lq8	257	8	of	of	IN
cord-264532-xfb94lq8	257	9	piglets	piglet	NNS
cord-264532-xfb94lq8	257	10	in	in	IN
cord-264532-xfb94lq8	257	11	pig	pig	NN
cord-264532-xfb94lq8	257	12	farms	farm	NNS
cord-264532-xfb94lq8	257	13	,	,	,
cord-264532-xfb94lq8	257	14	a	a	DT
cord-264532-xfb94lq8	257	15	mutant	mutant	JJ
cord-264532-xfb94lq8	257	16	form	form	NN
cord-264532-xfb94lq8	257	17	evolved	evolve	VBN
cord-264532-xfb94lq8	257	18	(	(	-LRB-
cord-264532-xfb94lq8	257	19	porcine	porcine	JJ
cord-264532-xfb94lq8	257	20	respiratory	respiratory	JJ
cord-264532-xfb94lq8	257	21	coronavirus	coronavirus	NN
cord-264532-xfb94lq8	257	22	,	,	,
cord-264532-xfb94lq8	257	23	or	or	CC
cord-264532-xfb94lq8	257	24	PRCV	PRCV	NNP
cord-264532-xfb94lq8	257	25	)	)	-RRB-
cord-264532-xfb94lq8	257	26	that	that	IN
cord-264532-xfb94lq8	257	27	not	not	RB
cord-264532-xfb94lq8	257	28	only	only	RB
cord-264532-xfb94lq8	257	29	had	have	VBD
cord-264532-xfb94lq8	257	30	altered	alter	VBN
cord-264532-xfb94lq8	257	31	tissue	tissue	NN
cord-264532-xfb94lq8	257	32	tropism	tropism	NN
cord-264532-xfb94lq8	257	33	but	but	CC
cord-264532-xfb94lq8	257	34	also	also	RB
cord-264532-xfb94lq8	257	35	apparently	apparently	RB
cord-264532-xfb94lq8	257	36	lower	low	JJR
cord-264532-xfb94lq8	257	37	virulence	virulence	NN
cord-264532-xfb94lq8	257	38	(	(	-LRB-
cord-264532-xfb94lq8	257	39	Kim	Kim	NNP
cord-264532-xfb94lq8	257	40	et	et	NNP
cord-264532-xfb94lq8	257	41	al	al	NNP
cord-264532-xfb94lq8	257	42	.	.	.
cord-264532-xfb94lq8	257	43	2000	2000	CD
cord-264532-xfb94lq8	257	44	)	)	-RRB-
cord-264532-xfb94lq8	257	45	.	.	.
cord-264532-xfb94lq8	258	1	PRCV	PRCV	NNP
cord-264532-xfb94lq8	258	2	differs	differ	VBZ
cord-264532-xfb94lq8	258	3	from	from	IN
cord-264532-xfb94lq8	258	4	TGEV	TGEV	NNP
cord-264532-xfb94lq8	258	5	by	by	IN
cord-264532-xfb94lq8	258	6	a	a	DT
cord-264532-xfb94lq8	258	7	small	small	JJ
cord-264532-xfb94lq8	258	8	deletion	deletion	NN
cord-264532-xfb94lq8	258	9	and	and	CC
cord-264532-xfb94lq8	258	10	a	a	DT
cord-264532-xfb94lq8	258	11	couple	couple	NN
cord-264532-xfb94lq8	258	12	point	point	NN
cord-264532-xfb94lq8	258	13	mutations	mutation	NNS
cord-264532-xfb94lq8	258	14	,	,	,
cord-264532-xfb94lq8	258	15	yet	yet	CC
cord-264532-xfb94lq8	258	16	it	-PRON-	PRP
cord-264532-xfb94lq8	258	17	infects	infect	VBZ
cord-264532-xfb94lq8	258	18	the	the	DT
cord-264532-xfb94lq8	258	19	pig	pig	NN
cord-264532-xfb94lq8	258	20	respiratory	respiratory	JJ
cord-264532-xfb94lq8	258	21	system	system	NN
cord-264532-xfb94lq8	258	22	and	and	CC
cord-264532-xfb94lq8	258	23	is	be	VBZ
cord-264532-xfb94lq8	258	24	often	often	RB
cord-264532-xfb94lq8	258	25	much	much	RB
cord-264532-xfb94lq8	258	26	less	less	RBR
cord-264532-xfb94lq8	258	27	virulent	virulent	JJ
cord-264532-xfb94lq8	258	28	than	than	IN
cord-264532-xfb94lq8	258	29	TGEV	TGEV	NNP
cord-264532-xfb94lq8	258	30	.	.	.
cord-264532-xfb94lq8	259	1	There	there	EX
cord-264532-xfb94lq8	259	2	is	be	VBZ
cord-264532-xfb94lq8	259	3	some	some	DT
cord-264532-xfb94lq8	259	4	antibody	antibody	NN
cord-264532-xfb94lq8	259	5	cross	cross	NN
cord-264532-xfb94lq8	259	6	reactivity	reactivity	NN
cord-264532-xfb94lq8	259	7	between	between	IN
cord-264532-xfb94lq8	259	8	TGEV	TGEV	NNP
cord-264532-xfb94lq8	259	9	and	and	CC
cord-264532-xfb94lq8	259	10	PRCV	PRCV	NNP
cord-264532-xfb94lq8	259	11	,	,	,
cord-264532-xfb94lq8	259	12	thus	thus	RB
cord-264532-xfb94lq8	259	13	the	the	DT
cord-264532-xfb94lq8	259	14	population	population	NN
cord-264532-xfb94lq8	259	15	of	of	IN
cord-264532-xfb94lq8	259	16	one	one	CD
cord-264532-xfb94lq8	259	17	form	form	NN
cord-264532-xfb94lq8	259	18	of	of	IN
cord-264532-xfb94lq8	259	19	the	the	DT
cord-264532-xfb94lq8	259	20	virus	virus	NN
cord-264532-xfb94lq8	259	21	interferes	interfere	VBZ
cord-264532-xfb94lq8	259	22	with	with	IN
cord-264532-xfb94lq8	259	23	the	the	DT
cord-264532-xfb94lq8	259	24	other	other	JJ
cord-264532-xfb94lq8	259	25	,	,	,
cord-264532-xfb94lq8	259	26	and	and	CC
cord-264532-xfb94lq8	259	27	it	-PRON-	PRP
cord-264532-xfb94lq8	259	28	is	be	VBZ
cord-264532-xfb94lq8	259	29	suspected	suspect	VBN
cord-264532-xfb94lq8	259	30	that	that	IN
cord-264532-xfb94lq8	259	31	a	a	DT
cord-264532-xfb94lq8	259	32	low	low	JJ
cord-264532-xfb94lq8	259	33	virulence	virulence	NN
cord-264532-xfb94lq8	259	34	PRCV	PRCV	NNP
cord-264532-xfb94lq8	259	35	was	be	VBD
cord-264532-xfb94lq8	259	36	responsible	responsible	JJ
cord-264532-xfb94lq8	259	37	for	for	IN
cord-264532-xfb94lq8	259	38	the	the	DT
cord-264532-xfb94lq8	259	39	disappearance	disappearance	NN
cord-264532-xfb94lq8	259	40	of	of	IN
cord-264532-xfb94lq8	259	41	TGEV	TGEV	NNP
cord-264532-xfb94lq8	259	42	in	in	IN
cord-264532-xfb94lq8	259	43	some	some	DT
cord-264532-xfb94lq8	259	44	pig	pig	NN
cord-264532-xfb94lq8	259	45	farm	farm	NN
cord-264532-xfb94lq8	259	46	areas	area	NNS
cord-264532-xfb94lq8	259	47	.	.	.
cord-264532-xfb94lq8	260	1	PRCV	PRCV	NNP
cord-264532-xfb94lq8	260	2	now	now	RB
cord-264532-xfb94lq8	260	3	exists	exist	VBZ
cord-264532-xfb94lq8	260	4	in	in	IN
cord-264532-xfb94lq8	260	5	forms	form	NNS
cord-264532-xfb94lq8	260	6	of	of	IN
cord-264532-xfb94lq8	260	7	high	high	JJ
cord-264532-xfb94lq8	260	8	and	and	CC
cord-264532-xfb94lq8	260	9	low	low	JJ
cord-264532-xfb94lq8	260	10	virulence	virulence	NN
cord-264532-xfb94lq8	260	11	.	.	.
cord-264532-xfb94lq8	261	1	This	this	DT
cord-264532-xfb94lq8	261	2	example	example	NN
cord-264532-xfb94lq8	261	3	thus	thus	RB
cord-264532-xfb94lq8	261	4	represents	represent	VBZ
cord-264532-xfb94lq8	261	5	what	what	WP
cord-264532-xfb94lq8	261	6	may	may	MD
cord-264532-xfb94lq8	261	7	be	be	VB
cord-264532-xfb94lq8	261	8	a	a	DT
cord-264532-xfb94lq8	261	9	single	single	JJ
cord-264532-xfb94lq8	261	10	mutant	mutant	JJ
cord-264532-xfb94lq8	261	11	invasion	invasion	NN
cord-264532-xfb94lq8	261	12	in	in	IN
cord-264532-xfb94lq8	261	13	the	the	DT
cord-264532-xfb94lq8	261	14	recent	recent	JJ
cord-264532-xfb94lq8	261	15	history	history	NN
cord-264532-xfb94lq8	261	16	of	of	IN
cord-264532-xfb94lq8	261	17	TGEV	TGEV	NNP
cord-264532-xfb94lq8	261	18	.	.	.
cord-264532-xfb94lq8	262	1	To	to	TO
cord-264532-xfb94lq8	262	2	what	what	WDT
cord-264532-xfb94lq8	262	3	extent	extent	NN
cord-264532-xfb94lq8	262	4	PRCV	PRCV	NNP
cord-264532-xfb94lq8	262	5	spread	spread	VBD
cord-264532-xfb94lq8	262	6	because	because	IN
cord-264532-xfb94lq8	262	7	it	-PRON-	PRP
cord-264532-xfb94lq8	262	8	could	could	MD
cord-264532-xfb94lq8	262	9	overcome	overcome	VB
cord-264532-xfb94lq8	262	10	prevailing	prevail	VBG
cord-264532-xfb94lq8	262	11	immunity	immunity	NN
cord-264532-xfb94lq8	262	12	(	(	-LRB-
cord-264532-xfb94lq8	262	13	as	as	IN
cord-264532-xfb94lq8	262	14	assumed	assume	VBN
cord-264532-xfb94lq8	262	15	by	by	IN
cord-264532-xfb94lq8	262	16	the	the	DT
cord-264532-xfb94lq8	262	17	invasion	invasion	NN
cord-264532-xfb94lq8	262	18	threshold	threshold	NN
cord-264532-xfb94lq8	262	19	model	model	NN
cord-264532-xfb94lq8	262	20	)	)	-RRB-
cord-264532-xfb94lq8	262	21	or	or	CC
cord-264532-xfb94lq8	262	22	because	because	IN
cord-264532-xfb94lq8	262	23	it	-PRON-	PRP
cord-264532-xfb94lq8	262	24	had	have	VBD
cord-264532-xfb94lq8	262	25	other	other	JJ
cord-264532-xfb94lq8	262	26	advantages	advantage	NNS
cord-264532-xfb94lq8	262	27	,	,	,
cord-264532-xfb94lq8	262	28	is	be	VBZ
cord-264532-xfb94lq8	262	29	not	not	RB
cord-264532-xfb94lq8	262	30	clear	clear	JJ
cord-264532-xfb94lq8	262	31	.	.	.
cord-264532-xfb94lq8	263	1	Another	another	DT
cord-264532-xfb94lq8	263	2	viral	viral	JJ
cord-264532-xfb94lq8	263	3	scourge	scourge	NN
cord-264532-xfb94lq8	263	4	of	of	IN
cord-264532-xfb94lq8	263	5	agriculture	agriculture	NN
cord-264532-xfb94lq8	263	6	is	be	VBZ
cord-264532-xfb94lq8	263	7	Marek	Marek	NNP
cord-264532-xfb94lq8	263	8	's	's	POS
cord-264532-xfb94lq8	263	9	disease	disease	NN
cord-264532-xfb94lq8	263	10	virus	virus	NN
cord-264532-xfb94lq8	263	11	(	(	-LRB-
cord-264532-xfb94lq8	263	12	MDV	MDV	NNP
cord-264532-xfb94lq8	263	13	)	)	-RRB-
cord-264532-xfb94lq8	263	14	of	of	IN
cord-264532-xfb94lq8	263	15	chickens	chicken	NNS
cord-264532-xfb94lq8	263	16	(	(	-LRB-
cord-264532-xfb94lq8	263	17	Hirai	Hirai	NNP
cord-264532-xfb94lq8	263	18	2001	2001	CD
cord-264532-xfb94lq8	263	19	;	;	:
cord-264532-xfb94lq8	263	20	Davison	Davison	NNP
cord-264532-xfb94lq8	263	21	and	and	CC
cord-264532-xfb94lq8	263	22	Nair	Nair	NNP
cord-264532-xfb94lq8	263	23	2004	2004	CD
cord-264532-xfb94lq8	263	24	)	)	-RRB-
cord-264532-xfb94lq8	263	25	.	.	.
cord-264532-xfb94lq8	264	1	MDV	MDV	NNP
cord-264532-xfb94lq8	264	2	has	have	VBZ
cord-264532-xfb94lq8	264	3	shown	show	VBN
cord-264532-xfb94lq8	264	4	a	a	DT
cord-264532-xfb94lq8	264	5	progressive	progressive	JJ
cord-264532-xfb94lq8	264	6	evolution	evolution	NN
cord-264532-xfb94lq8	264	7	toward	toward	IN
cord-264532-xfb94lq8	264	8	increasing	increase	VBG
cord-264532-xfb94lq8	264	9	virulence	virulence	NN
cord-264532-xfb94lq8	264	10	over	over	IN
cord-264532-xfb94lq8	264	11	four	four	CD
cord-264532-xfb94lq8	264	12	decades	decade	NNS
cord-264532-xfb94lq8	264	13	,	,	,
cord-264532-xfb94lq8	264	14	but	but	CC
cord-264532-xfb94lq8	264	15	again	again	RB
cord-264532-xfb94lq8	264	16	,	,	,
cord-264532-xfb94lq8	264	17	many	many	JJ
cord-264532-xfb94lq8	264	18	strains	strain	NNS
cord-264532-xfb94lq8	264	19	circulate	circulate	VBP
cord-264532-xfb94lq8	264	20	and	and	CC
cord-264532-xfb94lq8	264	21	some	some	DT
cord-264532-xfb94lq8	264	22	have	have	VBP
cord-264532-xfb94lq8	264	23	low	low	JJ
cord-264532-xfb94lq8	264	24	virulence	virulence	NN
cord-264532-xfb94lq8	264	25	.	.	.
cord-264532-xfb94lq8	265	1	Live	live	JJ
cord-264532-xfb94lq8	265	2	vaccines	vaccine	NNS
cord-264532-xfb94lq8	265	3	have	have	VBP
cord-264532-xfb94lq8	265	4	been	be	VBN
cord-264532-xfb94lq8	265	5	used	use	VBN
cord-264532-xfb94lq8	265	6	for	for	IN
cord-264532-xfb94lq8	265	7	three	three	CD
cord-264532-xfb94lq8	265	8	decades	decade	NNS
cord-264532-xfb94lq8	265	9	,	,	,
cord-264532-xfb94lq8	265	10	the	the	DT
cord-264532-xfb94lq8	265	11	virus	virus	NN
cord-264532-xfb94lq8	265	12	used	use	VBN
cord-264532-xfb94lq8	265	13	in	in	IN
cord-264532-xfb94lq8	265	14	them	-PRON-	PRP
cord-264532-xfb94lq8	265	15	having	have	VBG
cord-264532-xfb94lq8	265	16	been	be	VBN
cord-264532-xfb94lq8	265	17	changed	change	VBN
cord-264532-xfb94lq8	265	18	twice	twice	RB
cord-264532-xfb94lq8	265	19	.	.	.
cord-264532-xfb94lq8	266	1	As	as	IN
cord-264532-xfb94lq8	266	2	with	with	IN
cord-264532-xfb94lq8	266	3	FCV	FCV	NNP
cord-264532-xfb94lq8	266	4	,	,	,
cord-264532-xfb94lq8	266	5	the	the	DT
cord-264532-xfb94lq8	266	6	vaccines	vaccine	NNS
cord-264532-xfb94lq8	266	7	do	do	VBP
cord-264532-xfb94lq8	266	8	not	not	RB
cord-264532-xfb94lq8	266	9	prevent	prevent	VB
cord-264532-xfb94lq8	266	10	infection	infection	NN
cord-264532-xfb94lq8	266	11	and	and	CC
cord-264532-xfb94lq8	266	12	replication	replication	NN
cord-264532-xfb94lq8	266	13	by	by	IN
cord-264532-xfb94lq8	266	14	other	other	JJ
cord-264532-xfb94lq8	266	15	strains	strain	NNS
cord-264532-xfb94lq8	266	16	,	,	,
cord-264532-xfb94lq8	266	17	and	and	CC
cord-264532-xfb94lq8	266	18	it	-PRON-	PRP
cord-264532-xfb94lq8	266	19	is	be	VBZ
cord-264532-xfb94lq8	266	20	widely	widely	RB
cord-264532-xfb94lq8	266	21	suspected	suspect	VBN
cord-264532-xfb94lq8	266	22	that	that	IN
cord-264532-xfb94lq8	266	23	the	the	DT
cord-264532-xfb94lq8	266	24	vaccines	vaccine	NNS
cord-264532-xfb94lq8	266	25	may	may	MD
cord-264532-xfb94lq8	266	26	have	have	VB
cord-264532-xfb94lq8	266	27	fostered	foster	VBN
cord-264532-xfb94lq8	266	28	the	the	DT
cord-264532-xfb94lq8	266	29	evolution	evolution	NN
cord-264532-xfb94lq8	266	30	of	of	IN
cord-264532-xfb94lq8	266	31	progressively	progressively	RB
cord-264532-xfb94lq8	266	32	higher	high	JJR
cord-264532-xfb94lq8	266	33	virulence	virulence	NN
cord-264532-xfb94lq8	266	34	(	(	-LRB-
cord-264532-xfb94lq8	266	35	references	reference	NNS
cord-264532-xfb94lq8	266	36	within	within	IN
cord-264532-xfb94lq8	266	37	Davison	Davison	NNP
cord-264532-xfb94lq8	266	38	and	and	CC
cord-264532-xfb94lq8	266	39	Nair	Nair	NNP
cord-264532-xfb94lq8	266	40	2004	2004	CD
cord-264532-xfb94lq8	266	41	;	;	:
cord-264532-xfb94lq8	266	42	Hirai	Hirai	NNP
cord-264532-xfb94lq8	266	43	2001	2001	CD
cord-264532-xfb94lq8	266	44	)	)	-RRB-
cord-264532-xfb94lq8	266	45	.	.	.
cord-264532-xfb94lq8	267	1	(	(	-LRB-
cord-264532-xfb94lq8	267	2	We	-PRON-	PRP
cord-264532-xfb94lq8	267	3	lack	lack	VBP
cord-264532-xfb94lq8	267	4	the	the	DT
cord-264532-xfb94lq8	267	5	control	control	NN
cord-264532-xfb94lq8	267	6	of	of	IN
cord-264532-xfb94lq8	267	7	viral	viral	JJ
cord-264532-xfb94lq8	267	8	evolution	evolution	NN
cord-264532-xfb94lq8	267	9	at	at	IN
cord-264532-xfb94lq8	267	10	high	high	JJ
cord-264532-xfb94lq8	267	11	chicken	chicken	NN
cord-264532-xfb94lq8	267	12	density	density	NN
cord-264532-xfb94lq8	267	13	in	in	IN
cord-264532-xfb94lq8	267	14	the	the	DT
cord-264532-xfb94lq8	267	15	absence	absence	NN
cord-264532-xfb94lq8	267	16	of	of	IN
cord-264532-xfb94lq8	267	17	the	the	DT
cord-264532-xfb94lq8	267	18	vaccine	vaccine	NN
cord-264532-xfb94lq8	267	19	to	to	TO
cord-264532-xfb94lq8	267	20	have	have	VB
cord-264532-xfb94lq8	267	21	any	any	DT
cord-264532-xfb94lq8	267	22	confidence	confidence	NN
cord-264532-xfb94lq8	267	23	that	that	IN
cord-264532-xfb94lq8	267	24	the	the	DT
cord-264532-xfb94lq8	267	25	vaccine	vaccine	NN
cord-264532-xfb94lq8	267	26	was	be	VBD
cord-264532-xfb94lq8	267	27	the	the	DT
cord-264532-xfb94lq8	267	28	cause	cause	NN
cord-264532-xfb94lq8	267	29	in	in	IN
cord-264532-xfb94lq8	267	30	the	the	DT
cord-264532-xfb94lq8	267	31	higher	high	JJR
cord-264532-xfb94lq8	267	32	virulence	virulence	NN
cord-264532-xfb94lq8	267	33	evolution	evolution	NN
cord-264532-xfb94lq8	267	34	.	.	.
cord-264532-xfb94lq8	267	35	)	)	-RRB-
cord-264532-xfb94lq8	268	1	With	with	IN
cord-264532-xfb94lq8	268	2	MDV	MDV	NNP
cord-264532-xfb94lq8	268	3	,	,	,
cord-264532-xfb94lq8	268	4	there	there	EX
cord-264532-xfb94lq8	268	5	is	be	VBZ
cord-264532-xfb94lq8	268	6	considerable	considerable	JJ
cord-264532-xfb94lq8	268	7	ambiguity	ambiguity	NN
cord-264532-xfb94lq8	268	8	in	in	IN
cord-264532-xfb94lq8	268	9	the	the	DT
cord-264532-xfb94lq8	268	10	causes	cause	NNS
cord-264532-xfb94lq8	268	11	of	of	IN
cord-264532-xfb94lq8	268	12	virulence	virulence	NN
cord-264532-xfb94lq8	268	13	evolution	evolution	NN
cord-264532-xfb94lq8	268	14	as	as	RB
cord-264532-xfb94lq8	268	15	well	well	RB
cord-264532-xfb94lq8	268	16	as	as	IN
cord-264532-xfb94lq8	268	17	in	in	IN
cord-264532-xfb94lq8	268	18	the	the	DT
cord-264532-xfb94lq8	268	19	spectrum	spectrum	NN
cord-264532-xfb94lq8	268	20	of	of	IN
cord-264532-xfb94lq8	268	21	virulence	virulence	NN
cord-264532-xfb94lq8	268	22	evolution	evolution	NN
cord-264532-xfb94lq8	268	23	itself	-PRON-	PRP
cord-264532-xfb94lq8	268	24	.	.	.
cord-264532-xfb94lq8	269	1	It	-PRON-	PRP
cord-264532-xfb94lq8	269	2	may	may	MD
cord-264532-xfb94lq8	269	3	well	well	RB
cord-264532-xfb94lq8	269	4	be	be	VB
cord-264532-xfb94lq8	269	5	that	that	IN
cord-264532-xfb94lq8	269	6	vaccines	vaccine	NNS
cord-264532-xfb94lq8	269	7	have	have	VBP
cord-264532-xfb94lq8	269	8	selected	select	VBN
cord-264532-xfb94lq8	269	9	escape	escape	NN
cord-264532-xfb94lq8	269	10	mutants	mutant	NNS
cord-264532-xfb94lq8	269	11	time	time	NN
cord-264532-xfb94lq8	269	12	and	and	CC
cord-264532-xfb94lq8	269	13	again	again	RB
cord-264532-xfb94lq8	269	14	.	.	.
cord-264532-xfb94lq8	270	1	Whether	whether	IN
cord-264532-xfb94lq8	270	2	escape	escape	NN
cord-264532-xfb94lq8	270	3	mutants	mutant	NNS
cord-264532-xfb94lq8	270	4	retained	retain	VBN
cord-264532-xfb94lq8	270	5	near	near	IN
cord-264532-xfb94lq8	270	6	-	-	HYPH
cord-264532-xfb94lq8	270	7	optimal	optimal	JJ
cord-264532-xfb94lq8	270	8	virulence	virulence	NN
cord-264532-xfb94lq8	270	9	or	or	CC
cord-264532-xfb94lq8	270	10	not	not	RB
cord-264532-xfb94lq8	270	11	is	be	VBZ
cord-264532-xfb94lq8	270	12	difficult	difficult	JJ
cord-264532-xfb94lq8	270	13	to	to	TO
cord-264532-xfb94lq8	270	14	establish	establish	VB
cord-264532-xfb94lq8	270	15	,	,	,
cord-264532-xfb94lq8	270	16	because	because	IN
cord-264532-xfb94lq8	270	17	there	there	EX
cord-264532-xfb94lq8	270	18	is	be	VBZ
cord-264532-xfb94lq8	270	19	a	a	DT
cord-264532-xfb94lq8	270	20	strong	strong	JJ
cord-264532-xfb94lq8	270	21	ascertainment	ascertainment	NN
cord-264532-xfb94lq8	270	22	bias	bias	NN
cord-264532-xfb94lq8	271	1	-avirulent	-avirulent	NN
cord-264532-xfb94lq8	271	2	viruses	virus	NNS
cord-264532-xfb94lq8	271	3	are	be	VBP
cord-264532-xfb94lq8	271	4	not	not	RB
cord-264532-xfb94lq8	271	5	noticed	notice	VBN
cord-264532-xfb94lq8	271	6	by	by	IN
cord-264532-xfb94lq8	271	7	chicken	chicken	NN
cord-264532-xfb94lq8	271	8	farmers	farmer	NNS
cord-264532-xfb94lq8	271	9	.	.	.
cord-264532-xfb94lq8	272	1	Thus	thus	RB
cord-264532-xfb94lq8	272	2	,	,	,
cord-264532-xfb94lq8	272	3	without	without	IN
cord-264532-xfb94lq8	272	4	understanding	understand	VBG
cord-264532-xfb94lq8	272	5	the	the	DT
cord-264532-xfb94lq8	272	6	range	range	NN
cord-264532-xfb94lq8	272	7	of	of	IN
cord-264532-xfb94lq8	272	8	virulence	virulence	NN
cord-264532-xfb94lq8	272	9	levels	level	NNS
cord-264532-xfb94lq8	272	10	that	that	WDT
cord-264532-xfb94lq8	272	11	have	have	VBP
cord-264532-xfb94lq8	272	12	evolved	evolve	VBN
cord-264532-xfb94lq8	272	13	,	,	,
cord-264532-xfb94lq8	272	14	it	-PRON-	PRP
cord-264532-xfb94lq8	272	15	is	be	VBZ
cord-264532-xfb94lq8	272	16	not	not	RB
cord-264532-xfb94lq8	272	17	practical	practical	JJ
cord-264532-xfb94lq8	272	18	to	to	TO
cord-264532-xfb94lq8	272	19	discriminate	discriminate	VB
cord-264532-xfb94lq8	272	20	among	among	IN
cord-264532-xfb94lq8	272	21	the	the	DT
cord-264532-xfb94lq8	272	22	models	model	NNS
cord-264532-xfb94lq8	272	23	.	.	.
cord-264532-xfb94lq8	273	1	Such	such	JJ
cord-264532-xfb94lq8	273	2	a	a	DT
cord-264532-xfb94lq8	273	3	system	system	NN
cord-264532-xfb94lq8	273	4	seems	seem	VBZ
cord-264532-xfb94lq8	273	5	ripe	ripe	JJ
cord-264532-xfb94lq8	273	6	for	for	IN
cord-264532-xfb94lq8	273	7	testing	test	VBG
cord-264532-xfb94lq8	273	8	the	the	DT
cord-264532-xfb94lq8	273	9	models	model	NNS
cord-264532-xfb94lq8	273	10	,	,	,
cord-264532-xfb94lq8	273	11	however	however	RB
cord-264532-xfb94lq8	273	12	.	.	.
cord-264532-xfb94lq8	274	1	There	there	EX
cord-264532-xfb94lq8	274	2	is	be	VBZ
cord-264532-xfb94lq8	274	3	sufficient	sufficient	JJ
cord-264532-xfb94lq8	274	4	evidence	evidence	NN
cord-264532-xfb94lq8	274	5	to	to	TO
cord-264532-xfb94lq8	274	6	suggest	suggest	VB
cord-264532-xfb94lq8	274	7	that	that	IN
cord-264532-xfb94lq8	274	8	the	the	DT
cord-264532-xfb94lq8	274	9	invasion	invasion	NN
cord-264532-xfb94lq8	274	10	threshold	threshold	NN
cord-264532-xfb94lq8	274	11	model	model	NN
cord-264532-xfb94lq8	274	12	is	be	VBZ
cord-264532-xfb94lq8	274	13	relevant	relevant	JJ
cord-264532-xfb94lq8	274	14	to	to	IN
cord-264532-xfb94lq8	274	15	the	the	DT
cord-264532-xfb94lq8	274	16	evolution	evolution	NN
cord-264532-xfb94lq8	274	17	of	of	IN
cord-264532-xfb94lq8	274	18	many	many	JJ
cord-264532-xfb94lq8	274	19	infectious	infectious	JJ
cord-264532-xfb94lq8	274	20	agents	agent	NNS
cord-264532-xfb94lq8	274	21	,	,	,
cord-264532-xfb94lq8	274	22	but	but	CC
cord-264532-xfb94lq8	274	23	little	little	JJ
cord-264532-xfb94lq8	274	24	evidence	evidence	NN
cord-264532-xfb94lq8	274	25	to	to	TO
cord-264532-xfb94lq8	274	26	suggest	suggest	VB
cord-264532-xfb94lq8	274	27	how	how	WRB
cord-264532-xfb94lq8	274	28	often	often	RB
cord-264532-xfb94lq8	274	29	it	-PRON-	PRP
cord-264532-xfb94lq8	274	30	is	be	VBZ
cord-264532-xfb94lq8	274	31	important	important	JJ
cord-264532-xfb94lq8	274	32	.	.	.
cord-264532-xfb94lq8	275	1	Recommendations	recommendation	NNS
cord-264532-xfb94lq8	275	2	for	for	IN
cord-264532-xfb94lq8	275	3	use	use	NN
cord-264532-xfb94lq8	275	4	of	of	IN
cord-264532-xfb94lq8	275	5	this	this	DT
cord-264532-xfb94lq8	275	6	perspective	perspective	NN
cord-264532-xfb94lq8	275	7	are	be	VBP
cord-264532-xfb94lq8	275	8	thus	thus	RB
cord-264532-xfb94lq8	275	9	accordingly	accordingly	RB
cord-264532-xfb94lq8	275	10	muted	mute	VBN
cord-264532-xfb94lq8	275	11	.	.	.
cord-264532-xfb94lq8	276	1	Certainly	certainly	RB
cord-264532-xfb94lq8	276	2	,	,	,
cord-264532-xfb94lq8	276	3	it	-PRON-	PRP
cord-264532-xfb94lq8	276	4	seems	seem	VBZ
cord-264532-xfb94lq8	276	5	wise	wise	JJ
cord-264532-xfb94lq8	276	6	in	in	IN
cord-264532-xfb94lq8	276	7	virulence	virulence	NN
cord-264532-xfb94lq8	276	8	management	management	NN
cord-264532-xfb94lq8	276	9	efforts	effort	NNS
cord-264532-xfb94lq8	276	10	to	to	TO
cord-264532-xfb94lq8	276	11	be	be	VB
cord-264532-xfb94lq8	276	12	aware	aware	JJ
cord-264532-xfb94lq8	276	13	that	that	IN
cord-264532-xfb94lq8	276	14	a	a	DT
cord-264532-xfb94lq8	276	15	broader	broad	JJR
cord-264532-xfb94lq8	276	16	range	range	NN
cord-264532-xfb94lq8	276	17	of	of	IN
cord-264532-xfb94lq8	276	18	virulence	virulence	NN
cord-264532-xfb94lq8	276	19	might	may	MD
cord-264532-xfb94lq8	276	20	invade	invade	VB
cord-264532-xfb94lq8	276	21	than	than	IN
cord-264532-xfb94lq8	276	22	is	be	VBZ
cord-264532-xfb94lq8	276	23	optimal	optimal	JJ
cord-264532-xfb94lq8	276	24	and	and	CC
cord-264532-xfb94lq8	276	25	that	that	IN
cord-264532-xfb94lq8	276	26	evolution	evolution	NN
cord-264532-xfb94lq8	276	27	to	to	IN
cord-264532-xfb94lq8	276	28	an	an	DT
cord-264532-xfb94lq8	276	29	optimum	optimum	JJ
cord-264532-xfb94lq8	276	30	may	may	MD
cord-264532-xfb94lq8	276	31	not	not	RB
cord-264532-xfb94lq8	276	32	be	be	VB
cord-264532-xfb94lq8	276	33	rapid	rapid	JJ
cord-264532-xfb94lq8	276	34	.	.	.
cord-264532-xfb94lq8	277	1	It	-PRON-	PRP
cord-264532-xfb94lq8	277	2	would	would	MD
cord-264532-xfb94lq8	277	3	be	be	VB
cord-264532-xfb94lq8	277	4	obvious	obvious	JJ
cord-264532-xfb94lq8	277	5	folly	folly	NN
cord-264532-xfb94lq8	277	6	to	to	TO
cord-264532-xfb94lq8	277	7	ignore	ignore	VB
cord-264532-xfb94lq8	277	8	a	a	DT
cord-264532-xfb94lq8	277	9	case	case	NN
cord-264532-xfb94lq8	277	10	in	in	IN
cord-264532-xfb94lq8	277	11	which	which	WDT
cord-264532-xfb94lq8	277	12	the	the	DT
cord-264532-xfb94lq8	277	13	predicted	predict	VBN
cord-264532-xfb94lq8	277	14	optimum	optimum	NN
cord-264532-xfb94lq8	277	15	was	be	VBD
cord-264532-xfb94lq8	277	16	low	low	JJ
cord-264532-xfb94lq8	277	17	virulence	virulence	NN
cord-264532-xfb94lq8	277	18	but	but	CC
cord-264532-xfb94lq8	277	19	in	in	IN
cord-264532-xfb94lq8	277	20	which	which	WDT
cord-264532-xfb94lq8	277	21	a	a	DT
cord-264532-xfb94lq8	277	22	highly	highly	RB
cord-264532-xfb94lq8	277	23	virulent	virulent	JJ
cord-264532-xfb94lq8	277	24	parasite	parasite	NN
cord-264532-xfb94lq8	277	25	could	could	MD
cord-264532-xfb94lq8	277	26	invade	invade	VB
cord-264532-xfb94lq8	277	27	and	and	CC
cord-264532-xfb94lq8	277	28	persist	persist	VB
cord-264532-xfb94lq8	277	29	.	.	.
cord-264532-xfb94lq8	278	1	If	if	IN
cord-264532-xfb94lq8	278	2	the	the	DT
cord-264532-xfb94lq8	278	3	perspective	perspective	NN
cord-264532-xfb94lq8	278	4	offered	offer	VBN
cord-264532-xfb94lq8	278	5	here	here	RB
cord-264532-xfb94lq8	278	6	proves	prove	VBZ
cord-264532-xfb94lq8	278	7	to	to	TO
cord-264532-xfb94lq8	278	8	be	be	VB
cord-264532-xfb94lq8	278	9	broadly	broadly	RB
cord-264532-xfb94lq8	278	10	relevant	relevant	JJ
cord-264532-xfb94lq8	278	11	,	,	,
cord-264532-xfb94lq8	278	12	then	then	RB
cord-264532-xfb94lq8	278	13	its	-PRON-	PRP$
cord-264532-xfb94lq8	278	14	impact	impact	NN
cord-264532-xfb94lq8	278	15	is	be	VBZ
cord-264532-xfb94lq8	278	16	to	to	TO
cord-264532-xfb94lq8	278	17	support	support	VB
cord-264532-xfb94lq8	278	18	and	and	CC
cord-264532-xfb94lq8	278	19	even	even	RB
cord-264532-xfb94lq8	278	20	bolster	bolster	VB
cord-264532-xfb94lq8	278	21	any	any	DT
cord-264532-xfb94lq8	278	22	concerns	concern	NNS
cord-264532-xfb94lq8	278	23	about	about	IN
cord-264532-xfb94lq8	278	24	the	the	DT
cord-264532-xfb94lq8	278	25	evolution	evolution	NN
cord-264532-xfb94lq8	278	26	of	of	IN
cord-264532-xfb94lq8	278	27	high	high	JJ
cord-264532-xfb94lq8	278	28	virulence	virulence	NN
cord-264532-xfb94lq8	278	29	but	but	CC
cord-264532-xfb94lq8	278	30	also	also	RB
cord-264532-xfb94lq8	278	31	to	to	TO
cord-264532-xfb94lq8	278	32	raise	raise	VB
cord-264532-xfb94lq8	278	33	the	the	DT
cord-264532-xfb94lq8	278	34	specter	specter	NN
cord-264532-xfb94lq8	278	35	of	of	IN
cord-264532-xfb94lq8	278	36	temporary	temporary	JJ
cord-264532-xfb94lq8	278	37	high	high	JJ
cord-264532-xfb94lq8	278	38	virulence	virulence	NN
cord-264532-xfb94lq8	278	39	in	in	IN
cord-264532-xfb94lq8	278	40	parasites	parasite	NNS
cord-264532-xfb94lq8	278	41	expected	expect	VBN
cord-264532-xfb94lq8	278	42	to	to	TO
cord-264532-xfb94lq8	278	43	equilibrate	equilibrate	VB
cord-264532-xfb94lq8	278	44	at	at	IN
cord-264532-xfb94lq8	278	45	low	low	JJ
cord-264532-xfb94lq8	278	46	virulence	virulence	NN
cord-264532-xfb94lq8	278	47	.	.	.
cord-264532-xfb94lq8	279	1	The	the	DT
cord-264532-xfb94lq8	279	2	most	most	RBS
cord-264532-xfb94lq8	279	3	useful	useful	JJ
cord-264532-xfb94lq8	279	4	work	work	NN
cord-264532-xfb94lq8	279	5	at	at	IN
cord-264532-xfb94lq8	279	6	this	this	DT
cord-264532-xfb94lq8	279	7	stage	stage	NN
cord-264532-xfb94lq8	279	8	would	would	MD
cord-264532-xfb94lq8	279	9	be	be	VB
cord-264532-xfb94lq8	279	10	to	to	TO
cord-264532-xfb94lq8	279	11	contrast	contrast	VB
cord-264532-xfb94lq8	279	12	predicted	predict	VBD
cord-264532-xfb94lq8	279	13	virulence	virulence	NN
cord-264532-xfb94lq8	279	14	optima	optima	NNP
cord-264532-xfb94lq8	279	15	with	with	IN
cord-264532-xfb94lq8	279	16	actual	actual	JJ
cord-264532-xfb94lq8	279	17	virulence	virulence	NN
cord-264532-xfb94lq8	279	18	levels	level	NNS
cord-264532-xfb94lq8	279	19	over	over	IN
cord-264532-xfb94lq8	279	20	time	time	NN
cord-264532-xfb94lq8	279	21	.	.	.
cord-264532-xfb94lq8	280	1	Calculating	calculate	VBG
cord-264532-xfb94lq8	280	2	virulence	virulence	NN
cord-264532-xfb94lq8	280	3	optima	optima	NNP
cord-264532-xfb94lq8	280	4	has	have	VBZ
cord-264532-xfb94lq8	280	5	not	not	RB
cord-264532-xfb94lq8	280	6	met	meet	VBN
cord-264532-xfb94lq8	280	7	with	with	IN
cord-264532-xfb94lq8	280	8	much	much	JJ
cord-264532-xfb94lq8	280	9	success	success	NN
cord-264532-xfb94lq8	280	10	,	,	,
cord-264532-xfb94lq8	280	11	however	however	RB
cord-264532-xfb94lq8	280	12	,	,	,
cord-264532-xfb94lq8	280	13	likely	likely	JJ
cord-264532-xfb94lq8	280	14	because	because	IN
cord-264532-xfb94lq8	280	15	the	the	DT
cord-264532-xfb94lq8	280	16	optimum	optimum	NN
cord-264532-xfb94lq8	280	17	invariably	invariably	RB
cord-264532-xfb94lq8	280	18	depends	depend	VBZ
cord-264532-xfb94lq8	280	19	on	on	IN
cord-264532-xfb94lq8	280	20	an	an	DT
cord-264532-xfb94lq8	280	21	unknown	unknown	JJ
cord-264532-xfb94lq8	280	22	trade	trade	NN
cord-264532-xfb94lq8	280	23	-	-	HYPH
cord-264532-xfb94lq8	280	24	off	off	NN
cord-264532-xfb94lq8	280	25	and	and	CC
cord-264532-xfb94lq8	280	26	potentially	potentially	RB
cord-264532-xfb94lq8	280	27	on	on	IN
cord-264532-xfb94lq8	280	28	many	many	JJ
cord-264532-xfb94lq8	280	29	environmental	environmental	JJ
cord-264532-xfb94lq8	280	30	factors	factor	NNS
cord-264532-xfb94lq8	280	31	.	.	.
cord-264532-xfb94lq8	281	1	Thus	thus	RB
cord-264532-xfb94lq8	281	2	,	,	,
cord-264532-xfb94lq8	281	3	most	most	JJS
cord-264532-xfb94lq8	281	4	tests	test	NNS
cord-264532-xfb94lq8	281	5	of	of	IN
cord-264532-xfb94lq8	281	6	virulence	virulence	NN
cord-264532-xfb94lq8	281	7	evolution	evolution	NN
cord-264532-xfb94lq8	281	8	models	model	NNS
cord-264532-xfb94lq8	281	9	have	have	VBP
cord-264532-xfb94lq8	281	10	been	be	VBN
cord-264532-xfb94lq8	281	11	relative	relative	JJ
cord-264532-xfb94lq8	281	12	,	,	,
cord-264532-xfb94lq8	281	13	i.e.	i.e.	FW
cord-264532-xfb94lq8	281	14	,	,	,
cord-264532-xfb94lq8	281	15	correlating	correlate	VBG
cord-264532-xfb94lq8	281	16	virulence	virulence	NN
cord-264532-xfb94lq8	281	17	level	level	NN
cord-264532-xfb94lq8	281	18	with	with	IN
cord-264532-xfb94lq8	281	19	some	some	DT
cord-264532-xfb94lq8	281	20	environmental	environmental	JJ
cord-264532-xfb94lq8	281	21	characteristic	characteristic	NN
cord-264532-xfb94lq8	281	22	and	and	CC
cord-264532-xfb94lq8	281	23	determining	determine	VBG
cord-264532-xfb94lq8	281	24	if	if	IN
cord-264532-xfb94lq8	281	25	the	the	DT
cord-264532-xfb94lq8	281	26	correlation	correlation	NN
cord-264532-xfb94lq8	281	27	is	be	VBZ
cord-264532-xfb94lq8	281	28	in	in	IN
cord-264532-xfb94lq8	281	29	the	the	DT
cord-264532-xfb94lq8	281	30	right	right	JJ
cord-264532-xfb94lq8	281	31	direction	direction	NN
cord-264532-xfb94lq8	281	32	.	.	.
cord-264532-xfb94lq8	282	1	Direct	direct	JJ
cord-264532-xfb94lq8	282	2	,	,	,
cord-264532-xfb94lq8	282	3	quantitative	quantitative	JJ
cord-264532-xfb94lq8	282	4	tests	test	NNS
cord-264532-xfb94lq8	282	5	of	of	IN
cord-264532-xfb94lq8	282	6	virulence	virulence	NN
cord-264532-xfb94lq8	282	7	optima	optima	NNP
cord-264532-xfb94lq8	282	8	are	be	VBP
cord-264532-xfb94lq8	282	9	rare	rare	JJ
cord-264532-xfb94lq8	282	10	,	,	,
cord-264532-xfb94lq8	282	11	nonexistent	nonexistent	JJ
cord-264532-xfb94lq8	282	12	for	for	IN
cord-264532-xfb94lq8	282	13	human	human	JJ
cord-264532-xfb94lq8	282	14	pathogens	pathogen	NNS
cord-264532-xfb94lq8	282	15	.	.	.
cord-264532-xfb94lq8	283	1	If	if	IN
cord-264532-xfb94lq8	283	2	optima	optima	NNP
cord-264532-xfb94lq8	283	3	can	can	MD
cord-264532-xfb94lq8	283	4	not	not	RB
cord-264532-xfb94lq8	283	5	be	be	VB
cord-264532-xfb94lq8	283	6	calculated	calculate	VBN
cord-264532-xfb94lq8	283	7	,	,	,
cord-264532-xfb94lq8	283	8	then	then	RB
cord-264532-xfb94lq8	283	9	it	-PRON-	PRP
cord-264532-xfb94lq8	283	10	is	be	VBZ
cord-264532-xfb94lq8	283	11	of	of	IN
cord-264532-xfb94lq8	283	12	course	course	NN
cord-264532-xfb94lq8	283	13	difficult	difficult	JJ
cord-264532-xfb94lq8	283	14	to	to	TO
cord-264532-xfb94lq8	283	15	test	test	VB
cord-264532-xfb94lq8	283	16	any	any	DT
cord-264532-xfb94lq8	283	17	nonequilibrium	nonequilibrium	JJ
cord-264532-xfb94lq8	283	18	model	model	NN
cord-264532-xfb94lq8	283	19	against	against	IN
cord-264532-xfb94lq8	283	20	an	an	DT
cord-264532-xfb94lq8	283	21	optimality	optimality	NN
cord-264532-xfb94lq8	283	22	model	model	NN
cord-264532-xfb94lq8	283	23	.	.	.
cord-264532-xfb94lq8	284	1	But	but	CC
cord-264532-xfb94lq8	284	2	an	an	DT
cord-264532-xfb94lq8	284	3	alternative	alternative	NN
cord-264532-xfb94lq8	284	4	to	to	IN
cord-264532-xfb94lq8	284	5	testing	test	VBG
cord-264532-xfb94lq8	284	6	whether	whether	IN
cord-264532-xfb94lq8	284	7	virulence	virulence	NN
cord-264532-xfb94lq8	284	8	is	be	VBZ
cord-264532-xfb94lq8	284	9	optimal	optimal	JJ
cord-264532-xfb94lq8	284	10	is	be	VBZ
cord-264532-xfb94lq8	284	11	to	to	TO
cord-264532-xfb94lq8	284	12	observe	observe	VB
cord-264532-xfb94lq8	284	13	the	the	DT
cord-264532-xfb94lq8	284	14	dynamics	dynamic	NNS
cord-264532-xfb94lq8	284	15	of	of	IN
cord-264532-xfb94lq8	284	16	virulence	virulence	NN
cord-264532-xfb94lq8	284	17	evolution	evolution	NN
cord-264532-xfb94lq8	284	18	.	.	.
cord-264532-xfb94lq8	285	1	If	if	IN
cord-264532-xfb94lq8	285	2	virulence	virulence	NN
cord-264532-xfb94lq8	285	3	does	do	VBZ
cord-264532-xfb94lq8	285	4	not	not	RB
cord-264532-xfb94lq8	285	5	change	change	VB
cord-264532-xfb94lq8	285	6	over	over	IN
cord-264532-xfb94lq8	285	7	long	long	JJ
cord-264532-xfb94lq8	285	8	periods	period	NNS
cord-264532-xfb94lq8	285	9	after	after	IN
cord-264532-xfb94lq8	285	10	invasion	invasion	NN
cord-264532-xfb94lq8	285	11	,	,	,
cord-264532-xfb94lq8	285	12	despite	despite	IN
cord-264532-xfb94lq8	285	13	a	a	DT
cord-264532-xfb94lq8	285	14	dropping	drop	VBG
cord-264532-xfb94lq8	285	15	susceptible	susceptible	JJ
cord-264532-xfb94lq8	285	16	host	host	NN
cord-264532-xfb94lq8	285	17	density	density	NN
cord-264532-xfb94lq8	285	18	,	,	,
cord-264532-xfb94lq8	285	19	then	then	RB
cord-264532-xfb94lq8	285	20	it	-PRON-	PRP
cord-264532-xfb94lq8	285	21	would	would	MD
cord-264532-xfb94lq8	285	22	seem	seem	VB
cord-264532-xfb94lq8	285	23	that	that	IN
cord-264532-xfb94lq8	285	24	virulence	virulence	NN
cord-264532-xfb94lq8	285	25	has	have	VBZ
cord-264532-xfb94lq8	285	26	been	be	VBN
cord-264532-xfb94lq8	285	27	nonoptimal	nonoptimal	VBN
cord-264532-xfb94lq8	285	28	during	during	IN
cord-264532-xfb94lq8	285	29	much	much	JJ
cord-264532-xfb94lq8	285	30	of	of	IN
cord-264532-xfb94lq8	285	31	the	the	DT
cord-264532-xfb94lq8	285	32	time	time	NN
cord-264532-xfb94lq8	285	33	.	.	.
cord-264532-xfb94lq8	286	1	Coevolution	coevolution	NN
cord-264532-xfb94lq8	286	2	of	of	IN
cord-264532-xfb94lq8	286	3	hosts	host	NNS
cord-264532-xfb94lq8	286	4	and	and	CC
cord-264532-xfb94lq8	286	5	parasites	parasite	NNS
cord-264532-xfb94lq8	286	6	Population	population	NN
cord-264532-xfb94lq8	286	7	biology	biology	NN
cord-264532-xfb94lq8	286	8	of	of	IN
cord-264532-xfb94lq8	286	9	infectious	infectious	JJ
cord-264532-xfb94lq8	286	10	diseases	disease	NNS
cord-264532-xfb94lq8	286	11	:	:	:
cord-264532-xfb94lq8	286	12	part	part	NN
cord-264532-xfb94lq8	286	13	I	-PRON-	PRP
cord-264532-xfb94lq8	286	14	Virulence	Virulence	NNP
cord-264532-xfb94lq8	286	15	evolution	evolution	NN
cord-264532-xfb94lq8	286	16	in	in	IN
cord-264532-xfb94lq8	286	17	emerging	emerge	VBG
cord-264532-xfb94lq8	286	18	infectious	infectious	JJ
cord-264532-xfb94lq8	286	19	diseases	disease	NNS
cord-264532-xfb94lq8	286	20	Coevolution	Coevolution	NNP
cord-264532-xfb94lq8	286	21	of	of	IN
cord-264532-xfb94lq8	286	22	recovery	recovery	NN
cord-264532-xfb94lq8	286	23	ability	ability	NN
cord-264532-xfb94lq8	286	24	and	and	CC
cord-264532-xfb94lq8	286	25	virulence	virulence	NN
cord-264532-xfb94lq8	286	26	Modeling	model	VBG
cord-264532-xfb94lq8	286	27	within	within	IN
cord-264532-xfb94lq8	286	28	-	-	HYPH
cord-264532-xfb94lq8	286	29	host	host	NN
cord-264532-xfb94lq8	286	30	evolution	evolution	NN
cord-264532-xfb94lq8	286	31	of	of	IN
cord-264532-xfb94lq8	286	32	HIV	HIV	NNP
cord-264532-xfb94lq8	286	33	:	:	:
cord-264532-xfb94lq8	286	34	mutation	mutation	NN
cord-264532-xfb94lq8	286	35	,	,	,
cord-264532-xfb94lq8	286	36	competition	competition	NN
cord-264532-xfb94lq8	286	37	and	and	CC
cord-264532-xfb94lq8	286	38	strain	strain	VB
cord-264532-xfb94lq8	286	39	replacement	replacement	NN
cord-264532-xfb94lq8	286	40	Evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	286	41	feedback	feedback	NN
cord-264532-xfb94lq8	286	42	mediated	mediate	VBN
cord-264532-xfb94lq8	286	43	through	through	IN
cord-264532-xfb94lq8	286	44	population	population	NN
cord-264532-xfb94lq8	286	45	density	density	NN
cord-264532-xfb94lq8	286	46	,	,	,
cord-264532-xfb94lq8	286	47	illustrated	illustrate	VBN
cord-264532-xfb94lq8	286	48	with	with	IN
cord-264532-xfb94lq8	286	49	viruses	virus	NNS
cord-264532-xfb94lq8	286	50	in	in	IN
cord-264532-xfb94lq8	286	51	chemostats	chemostats	NNP
cord-264532-xfb94lq8	286	52	Evolution	Evolution	NNP
cord-264532-xfb94lq8	286	53	in	in	IN
cord-264532-xfb94lq8	286	54	Age	Age	NNP
cord-264532-xfb94lq8	286	55	-	-	HYPH
cord-264532-xfb94lq8	286	56	Structured	Structured	NNP
cord-264532-xfb94lq8	286	57	Populations	Populations	NNPS
cord-264532-xfb94lq8	287	1	A	a	DT
cord-264532-xfb94lq8	287	2	longitudinal	longitudinal	JJ
cord-264532-xfb94lq8	287	3	molecular	molecular	JJ
cord-264532-xfb94lq8	287	4	epidemiological	epidemiological	JJ
cord-264532-xfb94lq8	287	5	analysis	analysis	NN
cord-264532-xfb94lq8	287	6	of	of	IN
cord-264532-xfb94lq8	287	7	feline	feline	JJ
cord-264532-xfb94lq8	287	8	calicivirus	calicivirus	JJ
cord-264532-xfb94lq8	287	9	infection	infection	NN
cord-264532-xfb94lq8	287	10	in	in	IN
cord-264532-xfb94lq8	287	11	an	an	DT
cord-264532-xfb94lq8	287	12	animal	animal	NN
cord-264532-xfb94lq8	287	13	shelter	shelter	NN
cord-264532-xfb94lq8	287	14	:	:	:
cord-264532-xfb94lq8	287	15	a	a	DT
cord-264532-xfb94lq8	287	16	model	model	NN
cord-264532-xfb94lq8	287	17	for	for	IN
cord-264532-xfb94lq8	287	18	investigating	investigate	VBG
cord-264532-xfb94lq8	287	19	calicivirus	calicivirus	JJ
cord-264532-xfb94lq8	287	20	transmission	transmission	NN
cord-264532-xfb94lq8	287	21	within	within	IN
cord-264532-xfb94lq8	287	22	high	high	JJ
cord-264532-xfb94lq8	287	23	density	density	NN
cord-264532-xfb94lq8	287	24	,	,	,
cord-264532-xfb94lq8	287	25	high	high	JJ
cord-264532-xfb94lq8	287	26	turnover	turnover	NN
cord-264532-xfb94lq8	287	27	populations	population	NNS
cord-264532-xfb94lq8	287	28	On	on	IN
cord-264532-xfb94lq8	287	29	the	the	DT
cord-264532-xfb94lq8	287	30	evolution	evolution	NN
cord-264532-xfb94lq8	287	31	of	of	IN
cord-264532-xfb94lq8	287	32	virulence	virulence	NN
cord-264532-xfb94lq8	287	33	and	and	CC
cord-264532-xfb94lq8	287	34	the	the	DT
cord-264532-xfb94lq8	287	35	relationship	relationship	NN
cord-264532-xfb94lq8	287	36	between	between	IN
cord-264532-xfb94lq8	287	37	various	various	JJ
cord-264532-xfb94lq8	287	38	measures	measure	NNS
cord-264532-xfb94lq8	287	39	of	of	IN
cord-264532-xfb94lq8	287	40	mortality	mortality	NN
cord-264532-xfb94lq8	287	41	Applying	apply	VBG
cord-264532-xfb94lq8	287	42	population	population	NN
cord-264532-xfb94lq8	287	43	-	-	HYPH
cord-264532-xfb94lq8	287	44	genetic	genetic	JJ
cord-264532-xfb94lq8	287	45	models	model	NNS
cord-264532-xfb94lq8	287	46	in	in	IN
cord-264532-xfb94lq8	287	47	theoretical	theoretical	JJ
cord-264532-xfb94lq8	287	48	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	287	49	epidemiology	epidemiology	NN
cord-264532-xfb94lq8	287	50	Insights	Insights	NNP
cord-264532-xfb94lq8	287	51	from	from	IN
cord-264532-xfb94lq8	287	52	Price	Price	NNP
cord-264532-xfb94lq8	287	53	's	's	POS
cord-264532-xfb94lq8	287	54	equation	equation	NN
cord-264532-xfb94lq8	287	55	into	into	IN
cord-264532-xfb94lq8	287	56	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	287	57	epidemiology	epidemiology	NN
cord-264532-xfb94lq8	288	1	A	a	DT
cord-264532-xfb94lq8	288	2	general	general	JJ
cord-264532-xfb94lq8	288	3	theory	theory	NN
cord-264532-xfb94lq8	288	4	for	for	IN
cord-264532-xfb94lq8	288	5	the	the	DT
cord-264532-xfb94lq8	288	6	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	288	7	dynamics	dynamic	NNS
cord-264532-xfb94lq8	288	8	of	of	IN
cord-264532-xfb94lq8	288	9	virulence	virulence	NN
cord-264532-xfb94lq8	288	10	Adaptive	adaptive	JJ
cord-264532-xfb94lq8	288	11	dynamics	dynamic	NNS
cord-264532-xfb94lq8	288	12	of	of	IN
cord-264532-xfb94lq8	288	13	pathogen	pathogen	NN
cord-264532-xfb94lq8	288	14	-	-	HYPH
cord-264532-xfb94lq8	288	15	host	host	NN
cord-264532-xfb94lq8	288	16	interactions	interaction	NNS
cord-264532-xfb94lq8	288	17	Adaptive	adaptive	JJ
cord-264532-xfb94lq8	288	18	dynamics	dynamic	NNS
cord-264532-xfb94lq8	288	19	of	of	IN
cord-264532-xfb94lq8	288	20	infectious	infectious	JJ
cord-264532-xfb94lq8	288	21	diseases	disease	NNS
cord-264532-xfb94lq8	289	1	:	:	:
cord-264532-xfb94lq8	289	2	in	in	IN
cord-264532-xfb94lq8	289	3	pursuit	pursuit	NN
cord-264532-xfb94lq8	289	4	of	of	IN
cord-264532-xfb94lq8	289	5	virulence	virulence	NN
cord-264532-xfb94lq8	289	6	management	management	NN
cord-264532-xfb94lq8	289	7	Challenging	challenge	VBG
cord-264532-xfb94lq8	289	8	the	the	DT
cord-264532-xfb94lq8	289	9	trade	trade	NN
cord-264532-xfb94lq8	289	10	-	-	HYPH
cord-264532-xfb94lq8	289	11	off	off	RP
cord-264532-xfb94lq8	289	12	model	model	NN
cord-264532-xfb94lq8	289	13	for	for	IN
cord-264532-xfb94lq8	289	14	the	the	DT
cord-264532-xfb94lq8	289	15	evolution	evolution	NN
cord-264532-xfb94lq8	289	16	of	of	IN
cord-264532-xfb94lq8	289	17	virulence	virulence	NN
cord-264532-xfb94lq8	289	18	:	:	:
cord-264532-xfb94lq8	289	19	is	be	VBZ
cord-264532-xfb94lq8	289	20	virulence	virulence	NN
cord-264532-xfb94lq8	289	21	management	management	NN
cord-264532-xfb94lq8	289	22	feasible	feasible	JJ
cord-264532-xfb94lq8	289	23	?	?	.
cord-264532-xfb94lq8	290	1	The	the	DT
cord-264532-xfb94lq8	290	2	evolution	evolution	NN
cord-264532-xfb94lq8	290	3	of	of	IN
cord-264532-xfb94lq8	290	4	parasitic	parasitic	JJ
cord-264532-xfb94lq8	290	5	diseases	disease	NNS
cord-264532-xfb94lq8	290	6	Evolution	evolution	NN
cord-264532-xfb94lq8	290	7	of	of	IN
cord-264532-xfb94lq8	290	8	Infectious	Infectious	NNP
cord-264532-xfb94lq8	290	9	Disease	Disease	NNP
cord-264532-xfb94lq8	290	10	Ecological	ecological	JJ
cord-264532-xfb94lq8	290	11	and	and	CC
cord-264532-xfb94lq8	290	12	immunological	immunological	JJ
cord-264532-xfb94lq8	290	13	determinants	determinant	NNS
cord-264532-xfb94lq8	290	14	of	of	IN
cord-264532-xfb94lq8	290	15	influenza	influenza	NN
cord-264532-xfb94lq8	290	16	evolution	evolution	NN
cord-264532-xfb94lq8	290	17	Models	model	NNS
cord-264532-xfb94lq8	290	18	of	of	IN
cord-264532-xfb94lq8	290	19	parasite	parasite	NN
cord-264532-xfb94lq8	290	20	virulence	virulence	NN
cord-264532-xfb94lq8	290	21	Imperfect	imperfect	JJ
cord-264532-xfb94lq8	290	22	vaccines	vaccine	NNS
cord-264532-xfb94lq8	290	23	and	and	CC
cord-264532-xfb94lq8	290	24	the	the	DT
cord-264532-xfb94lq8	290	25	evolution	evolution	NN
cord-264532-xfb94lq8	290	26	of	of	IN
cord-264532-xfb94lq8	290	27	pathogen	pathogen	NN
cord-264532-xfb94lq8	290	28	virulence	virulence	NN
cord-264532-xfb94lq8	290	29	Imperfect	imperfect	JJ
cord-264532-xfb94lq8	290	30	vaccination	vaccination	NN
cord-264532-xfb94lq8	290	31	:	:	:
cord-264532-xfb94lq8	290	32	some	some	DT
cord-264532-xfb94lq8	290	33	epidemiological	epidemiological	JJ
cord-264532-xfb94lq8	290	34	and	and	CC
cord-264532-xfb94lq8	290	35	evolutionary	evolutionary	JJ
cord-264532-xfb94lq8	290	36	consequences	consequence	NNS
cord-264532-xfb94lq8	290	37	Evolution	evolution	NN
cord-264532-xfb94lq8	290	38	of	of	IN
cord-264532-xfb94lq8	290	39	virulence	virulence	NN
cord-264532-xfb94lq8	290	40	:	:	:
cord-264532-xfb94lq8	290	41	interdependence	interdependence	NN
cord-264532-xfb94lq8	290	42	,	,	,
cord-264532-xfb94lq8	290	43	constraints	constraint	NNS
cord-264532-xfb94lq8	290	44	,	,	,
cord-264532-xfb94lq8	290	45	and	and	CC
cord-264532-xfb94lq8	290	46	selection	selection	NN
cord-264532-xfb94lq8	290	47	using	use	VBG
cord-264532-xfb94lq8	290	48	nested	nest	VBN
cord-264532-xfb94lq8	290	49	models	model	NNS
cord-264532-xfb94lq8	290	50	Testing	test	VBG
cord-264532-xfb94lq8	290	51	optimality	optimality	NN
cord-264532-xfb94lq8	290	52	with	with	IN
cord-264532-xfb94lq8	290	53	experimental	experimental	JJ
cord-264532-xfb94lq8	290	54	evolution	evolution	NN
cord-264532-xfb94lq8	290	55	:	:	:
cord-264532-xfb94lq8	290	56	lysis	lysis	NN
cord-264532-xfb94lq8	290	57	time	time	NN
cord-264532-xfb94lq8	290	58	in	in	IN
cord-264532-xfb94lq8	290	59	a	a	DT
cord-264532-xfb94lq8	290	60	bacteriophage	bacteriophage	NN
cord-264532-xfb94lq8	290	61	.	.	.
cord-264532-xfb94lq8	291	1	Evolution	evolution	NN
cord-264532-xfb94lq8	291	2	Marek	Marek	NNP
cord-264532-xfb94lq8	291	3	's	's	POS
cord-264532-xfb94lq8	291	4	Disease	Disease	NNP
cord-264532-xfb94lq8	291	5	:	:	:
cord-264532-xfb94lq8	291	6	Current	current	JJ
cord-264532-xfb94lq8	291	7	Topics	topic	NNS
cord-264532-xfb94lq8	291	8	in	in	IN
cord-264532-xfb94lq8	291	9	Microbiology	Microbiology	NNP
cord-264532-xfb94lq8	291	10	and	and	CC
cord-264532-xfb94lq8	291	11	Immunology	Immunology	NNP
cord-264532-xfb94lq8	291	12	Influenza	Influenza	NNP
cord-264532-xfb94lq8	291	13	pandemics	pandemic	NNS
cord-264532-xfb94lq8	291	14	of	of	IN
cord-264532-xfb94lq8	291	15	the	the	DT
cord-264532-xfb94lq8	291	16	20th	20th	JJ
cord-264532-xfb94lq8	291	17	century	century	NN
cord-264532-xfb94lq8	291	18	Molecular	molecular	JJ
cord-264532-xfb94lq8	291	19	characterization	characterization	NN
cord-264532-xfb94lq8	291	20	and	and	CC
cord-264532-xfb94lq8	291	21	pathogenesis	pathogenesis	NN
cord-264532-xfb94lq8	291	22	of	of	IN
cord-264532-xfb94lq8	291	23	transmissible	transmissible	JJ
cord-264532-xfb94lq8	291	24	gastroenteritis	gastroenteritis	NN
cord-264532-xfb94lq8	291	25	coronavirus	coronavirus	NN
cord-264532-xfb94lq8	291	26	(	(	-LRB-
cord-264532-xfb94lq8	291	27	TGEV	TGEV	NNP
cord-264532-xfb94lq8	291	28	)	)	-RRB-
cord-264532-xfb94lq8	291	29	and	and	CC
cord-264532-xfb94lq8	291	30	porcine	porcine	JJ
cord-264532-xfb94lq8	291	31	respiratory	respiratory	JJ
cord-264532-xfb94lq8	291	32	coronavirus	coronavirus	NN
cord-264532-xfb94lq8	292	1	(	(	-LRB-
cord-264532-xfb94lq8	292	2	PRCV	PRCV	NNP
cord-264532-xfb94lq8	292	3	)	)	-RRB-
cord-264532-xfb94lq8	292	4	field	field	NN
cord-264532-xfb94lq8	292	5	isolates	isolate	NNS
cord-264532-xfb94lq8	292	6	co	co	NN
cord-264532-xfb94lq8	292	7	-	-	NN
cord-264532-xfb94lq8	292	8	circulating	circulate	VBG
cord-264532-xfb94lq8	292	9	in	in	IN
cord-264532-xfb94lq8	292	10	a	a	DT
cord-264532-xfb94lq8	292	11	swine	swine	NN
cord-264532-xfb94lq8	292	12	herd	herd	NN
cord-264532-xfb94lq8	293	1	The	the	DT
cord-264532-xfb94lq8	293	2	evolution	evolution	NN
cord-264532-xfb94lq8	293	3	of	of	IN
cord-264532-xfb94lq8	293	4	virulence	virulence	NN
cord-264532-xfb94lq8	293	5	in	in	IN
cord-264532-xfb94lq8	293	6	parasites	parasite	NNS
cord-264532-xfb94lq8	293	7	and	and	CC
cord-264532-xfb94lq8	293	8	pathogens	pathogen	NNS
cord-264532-xfb94lq8	293	9	:	:	:
cord-264532-xfb94lq8	293	10	reconciliation	reconciliation	NN
cord-264532-xfb94lq8	293	11	between	between	IN
cord-264532-xfb94lq8	293	12	two	two	CD
cord-264532-xfb94lq8	293	13	competing	compete	VBG
cord-264532-xfb94lq8	293	14	hypotheses	hypothesis	NNS
cord-264532-xfb94lq8	293	15	Short	short	JJ
cord-264532-xfb94lq8	293	16	-	-	HYPH
cord-264532-xfb94lq8	293	17	sighted	sighted	JJ
cord-264532-xfb94lq8	293	18	evolution	evolution	NN
cord-264532-xfb94lq8	293	19	and	and	CC
cord-264532-xfb94lq8	293	20	the	the	DT
cord-264532-xfb94lq8	293	21	virulence	virulence	NN
cord-264532-xfb94lq8	293	22	of	of	IN
cord-264532-xfb94lq8	293	23	pathogenic	pathogenic	JJ
cord-264532-xfb94lq8	293	24	microorganisms	microorganism	NNS
cord-264532-xfb94lq8	293	25	Rational	rational	JJ
cord-264532-xfb94lq8	293	26	design	design	NN
cord-264532-xfb94lq8	293	27	of	of	IN
cord-264532-xfb94lq8	293	28	genetically	genetically	RB
cord-264532-xfb94lq8	293	29	stable	stable	JJ
cord-264532-xfb94lq8	293	30	,	,	,
cord-264532-xfb94lq8	293	31	live	live	RB
cord-264532-xfb94lq8	293	32	-	-	HYPH
cord-264532-xfb94lq8	293	33	attenuated	attenuated	JJ
cord-264532-xfb94lq8	293	34	poliovirus	poliovirus	NN
cord-264532-xfb94lq8	293	35	vaccines	vaccine	NNS
cord-264532-xfb94lq8	293	36	of	of	IN
cord-264532-xfb94lq8	293	37	all	all	DT
cord-264532-xfb94lq8	293	38	three	three	CD
cord-264532-xfb94lq8	293	39	serotypes	serotype	NNS
cord-264532-xfb94lq8	293	40	:	:	:
cord-264532-xfb94lq8	293	41	relevance	relevance	NN
cord-264532-xfb94lq8	293	42	to	to	IN
cord-264532-xfb94lq8	293	43	poliomyelitis	poliomyelitis	NN
cord-264532-xfb94lq8	293	44	eradication	eradication	NN
cord-264532-xfb94lq8	294	1	How	how	WRB
cord-264532-xfb94lq8	294	2	should	should	MD
cord-264532-xfb94lq8	294	3	we	-PRON-	PRP
cord-264532-xfb94lq8	294	4	define	define	VB
cord-264532-xfb94lq8	294	5	'	'	``
cord-264532-xfb94lq8	294	6	fitness	fitness	NN
cord-264532-xfb94lq8	294	7	'	'	''
cord-264532-xfb94lq8	294	8	for	for	IN
cord-264532-xfb94lq8	294	9	general	general	JJ
cord-264532-xfb94lq8	294	10	ecological	ecological	JJ
cord-264532-xfb94lq8	294	11	scenarios	scenario	NNS
cord-264532-xfb94lq8	295	1	Avian	avian	JJ
cord-264532-xfb94lq8	295	2	influenza	influenza	NN
cord-264532-xfb94lq8	295	3	.	.	.
cord-264532-xfb94lq8	296	1	Pandemic	pandemic	NN
cord-264532-xfb94lq8	296	2	skeptics	skeptic	NNS
cord-264532-xfb94lq8	296	3	warn	warn	VBP
cord-264532-xfb94lq8	296	4	against	against	IN
cord-264532-xfb94lq8	296	5	crying	cry	VBG
cord-264532-xfb94lq8	296	6	wolf	wolf	NNP
cord-264532-xfb94lq8	296	7	Epidemiology	Epidemiology	NNP
cord-264532-xfb94lq8	296	8	and	and	CC
cord-264532-xfb94lq8	296	9	molecular	molecular	JJ
cord-264532-xfb94lq8	296	10	characterization	characterization	NN
cord-264532-xfb94lq8	296	11	of	of	IN
cord-264532-xfb94lq8	296	12	co	co	NN
cord-264532-xfb94lq8	296	13	-	-	JJ
cord-264532-xfb94lq8	296	14	circulating	circulating	JJ
cord-264532-xfb94lq8	296	15	influenza	influenza	NN
cord-264532-xfb94lq8	296	16	A	a	NN
cord-264532-xfb94lq8	296	17	/	/	SYM
cord-264532-xfb94lq8	296	18	H3N2	H3N2	NNP
cord-264532-xfb94lq8	296	19	virus	virus	NN
cord-264532-xfb94lq8	296	20	variants	variant	NNS
cord-264532-xfb94lq8	296	21	in	in	IN
cord-264532-xfb94lq8	296	22	children	child	NNS
cord-264532-xfb94lq8	297	1	Chicken	chicken	NN
cord-264532-xfb94lq8	297	2	little	little	JJ
cord-264532-xfb94lq8	297	3	Feline	feline	JJ
cord-264532-xfb94lq8	297	4	calicivirus	calicivirus	NNP
cord-264532-xfb94lq8	297	5	Optimal	Optimal	NNP
cord-264532-xfb94lq8	297	6	growth	growth	NN
cord-264532-xfb94lq8	297	7	schedule	schedule	NN
cord-264532-xfb94lq8	297	8	of	of	IN
cord-264532-xfb94lq8	297	9	pathogens	pathogen	NNS
cord-264532-xfb94lq8	297	10	within	within	IN
cord-264532-xfb94lq8	297	11	a	a	DT
cord-264532-xfb94lq8	297	12	host	host	NN
cord-264532-xfb94lq8	297	13	:	:	:
cord-264532-xfb94lq8	298	1	switching	switch	VBG
cord-264532-xfb94lq8	298	2	between	between	IN
cord-264532-xfb94lq8	298	3	lytic	lytic	JJ
cord-264532-xfb94lq8	298	4	and	and	CC
cord-264532-xfb94lq8	298	5	latent	latent	JJ
cord-264532-xfb94lq8	298	6	cycles	cycle	NNS
cord-264532-xfb94lq8	298	7	Spontaneous	spontaneous	JJ
cord-264532-xfb94lq8	298	8	mutation	mutation	NN
cord-264532-xfb94lq8	298	9	rate	rate	NN
cord-264532-xfb94lq8	298	10	of	of	IN
cord-264532-xfb94lq8	298	11	measles	measle	NNS
cord-264532-xfb94lq8	298	12	virus	virus	NN
cord-264532-xfb94lq8	298	13	:	:	:
cord-264532-xfb94lq8	298	14	direct	direct	JJ
cord-264532-xfb94lq8	298	15	estimation	estimation	NN
cord-264532-xfb94lq8	298	16	based	base	VBN
cord-264532-xfb94lq8	298	17	on	on	IN
cord-264532-xfb94lq8	298	18	mutations	mutation	NNS
cord-264532-xfb94lq8	298	19	conferring	confer	VBG
cord-264532-xfb94lq8	298	20	monoclonal	monoclonal	JJ
cord-264532-xfb94lq8	298	21	antibody	antibody	NN
cord-264532-xfb94lq8	298	22	resistance	resistance	NN
cord-264532-xfb94lq8	298	23	Influenza	influenza	NN
cord-264532-xfb94lq8	298	24	:	:	:
cord-264532-xfb94lq8	298	25	the	the	DT
cord-264532-xfb94lq8	298	26	mother	mother	NN
cord-264532-xfb94lq8	298	27	of	of	IN
cord-264532-xfb94lq8	298	28	all	all	DT
cord-264532-xfb94lq8	298	29	pandemics	pandemic	NNS
cord-264532-xfb94lq8	298	30	Evolution	evolution	NN
cord-264532-xfb94lq8	298	31	and	and	CC
cord-264532-xfb94lq8	298	32	ecology	ecology	NN
cord-264532-xfb94lq8	298	33	of	of	IN
cord-264532-xfb94lq8	298	34	influenza	influenza	NN
cord-264532-xfb94lq8	298	35	A	a	DT
cord-264532-xfb94lq8	298	36	viruses	virus	NNS
cord-264532-xfb94lq8	299	1	H5N1	H5N1	NNP
cord-264532-xfb94lq8	299	2	outbreaks	outbreak	NNS
cord-264532-xfb94lq8	299	3	and	and	CC
cord-264532-xfb94lq8	299	4	enzootic	enzootic	JJ
cord-264532-xfb94lq8	299	5	influenza	influenza	NN
cord-264532-xfb94lq8	300	1	A	a	DT
cord-264532-xfb94lq8	300	2	Primer	Primer	NNP
cord-264532-xfb94lq8	300	3	of	of	IN
cord-264532-xfb94lq8	300	4	Population	Population	NNP
cord-264532-xfb94lq8	300	5	Biology	Biology	NNP
cord-264532-xfb94lq8	301	1	We	-PRON-	PRP
cord-264532-xfb94lq8	301	2	thank	thank	VBP
cord-264532-xfb94lq8	301	3	Troy	Troy	NNP
cord-264532-xfb94lq8	301	4	Day	Day	NNP
cord-264532-xfb94lq8	301	5	,	,	,
cord-264532-xfb94lq8	301	6	Carl	Carl	NNP
cord-264532-xfb94lq8	301	7	Bergstrom	Bergstrom	NNP
cord-264532-xfb94lq8	301	8	,	,	,
cord-264532-xfb94lq8	301	9	and	and	CC
cord-264532-xfb94lq8	301	10	Robin	Robin	NNP
cord-264532-xfb94lq8	301	11	Bush	Bush	NNP
cord-264532-xfb94lq8	301	12	for	for	IN
cord-264532-xfb94lq8	301	13	comments	comment	NNS
cord-264532-xfb94lq8	301	14	.	.	.
cord-264532-xfb94lq8	302	1	Two	two	CD
cord-264532-xfb94lq8	302	2	reviewers	reviewer	NNS
cord-264532-xfb94lq8	302	3	essentially	essentially	RB
cord-264532-xfb94lq8	302	4	did	do	VBD
cord-264532-xfb94lq8	302	5	the	the	DT
cord-264532-xfb94lq8	302	6	literature	literature	NN
cord-264532-xfb94lq8	302	7	work	work	NN
cord-264532-xfb94lq8	302	8	for	for	IN
cord-264532-xfb94lq8	302	9	this	this	DT
cord-264532-xfb94lq8	302	10	paper	paper	NN
cord-264532-xfb94lq8	302	11	.	.	.
cord-264532-xfb94lq8	303	1	Our	-PRON-	PRP$
cord-264532-xfb94lq8	303	2	choice	choice	NN
cord-264532-xfb94lq8	303	3	for	for	IN
cord-264532-xfb94lq8	303	4	some	some	DT
cord-264532-xfb94lq8	303	5	of	of	IN
cord-264532-xfb94lq8	303	6	the	the	DT
cord-264532-xfb94lq8	303	7	examples	example	NNS
cord-264532-xfb94lq8	303	8	reviewed	review	VBN
cord-264532-xfb94lq8	303	9	above	above	RB
cord-264532-xfb94lq8	303	10	was	be	VBD
cord-264532-xfb94lq8	303	11	inspired	inspire	VBN
cord-264532-xfb94lq8	303	12	by	by	IN
cord-264532-xfb94lq8	303	13	a	a	DT
cord-264532-xfb94lq8	303	14	seminar	seminar	NN
cord-264532-xfb94lq8	303	15	of	of	IN
cord-264532-xfb94lq8	303	16	A.	A.	NNP
cord-264532-xfb94lq8	303	17	Read	Read	NNP
cord-264532-xfb94lq8	303	18	.	.	.
cord-264532-xfb94lq8	304	1	This	this	DT
cord-264532-xfb94lq8	304	2	work	work	NN
cord-264532-xfb94lq8	304	3	was	be	VBD
cord-264532-xfb94lq8	304	4	supported	support	VBN
cord-264532-xfb94lq8	304	5	by	by	IN
cord-264532-xfb94lq8	304	6	NIH	NIH	NNP
cord-264532-xfb94lq8	304	7	GM57756	GM57756	NNP
cord-264532-xfb94lq8	304	8	to	to	IN
cord-264532-xfb94lq8	304	9	JB	JB	NNP
cord-264532-xfb94lq8	304	10	.	.	.
cord-264532-xfb94lq8	305	1	JB	JB	NNP
cord-264532-xfb94lq8	305	2	also	also	RB
cord-264532-xfb94lq8	305	3	receives	receive	VBZ
cord-264532-xfb94lq8	305	4	support	support	NN
cord-264532-xfb94lq8	305	5	as	as	IN
cord-264532-xfb94lq8	305	6	the	the	DT
cord-264532-xfb94lq8	305	7	Miescher	Miescher	NNP
cord-264532-xfb94lq8	305	8	Regents	Regents	NNP
cord-264532-xfb94lq8	305	9	Professor	Professor	NNP
cord-264532-xfb94lq8	305	10	at	at	IN
cord-264532-xfb94lq8	305	11	the	the	DT
cord-264532-xfb94lq8	305	12	University	University	NNP
cord-264532-xfb94lq8	305	13	of	of	IN
cord-264532-xfb94lq8	305	14	Texas	Texas	NNP
cord-264532-xfb94lq8	305	15	.	.	.
cord-264532-xfb94lq8	306	1	DE	DE	NNP
cord-264532-xfb94lq8	306	2	was	be	VBD
cord-264532-xfb94lq8	306	3	supported	support	VBN
cord-264532-xfb94lq8	306	4	by	by	IN
cord-264532-xfb94lq8	306	5	the	the	DT
cord-264532-xfb94lq8	306	6	Swiss	Swiss	NNP
cord-264532-xfb94lq8	306	7	National	National	NNP
cord-264532-xfb94lq8	306	8	Fonds	Fonds	NNP
cord-264532-xfb94lq8	306	9	.	.	.