id author title date pages extension mime words sentences flesch summary cache txt cord-329149-1giy1fow Martinez-Martin, Nadia Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions 2017-02-22 .txt text/plain 11180 487 27 Despite SPR and related methods offering higher sensitivity for detection of transient Biochemical and MS PDGFR identified as a high affinity cell surface receptor for the CMV gHgLgO protein complex [21] Herpes simplex viruses (HSVs) Biophysical Secreted and plasma membrane-expressed glycoprotein G targets a specific set of human chemokines with high affinity [22] Human immunodeficiency virus type 1 (HIV) Despite the undoubted importance of the biochemical and biophysical approaches to the study of host-pathogen interactions, the aforementioned limitations have motivated the development of alternative technologies for large-scale analysis of ePPIs. From the initial utilization of microarrays for detection of PPI over a decade ago, human proteome chips containing thousands of recombinant proteins have been generated, some of which are now commercially available. ./cache/cord-329149-1giy1fow.txt ./txt/cord-329149-1giy1fow.txt