id author title date pages extension mime words sentences flesch summary cache txt cord-263312-x7f0hn7f Tzelepis, Ilias Drosophila melanogaster: a first step and a stepping-stone to anti-infectives 2013-08-28 .txt text/plain 3754 176 37 Drug screening in Drosophila offers to fill the gap between in vitro and mammalian model host testing by eliminating compounds that are toxic or have reduced bioavailability and by identifying others that may boost innate host defence or selectively reduce microbial virulence in a whole-organism setting. Drug screening in Drosophila offers to fill the gap between in vitro and mammalian model host testing by eliminating compounds that are toxic or have reduced bioavailability and by identifying others that may boost innate host defence or selectively reduce microbial virulence in a whole-organism setting. Flies have significant similarities with humans enabling a facile and cost effective assessment of anti-infective drugs during the interaction of microbes with a host. Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection ./cache/cord-263312-x7f0hn7f.txt ./txt/cord-263312-x7f0hn7f.txt