id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-262682-gsvswr7v	Hedblom, Grant A.	Segmented Filamentous Bacteria – Metabolism Meets Immunity	2018-08-24		.txt	text/plain	6710	285	39	SFB have recently garnered attention due to their role in promoting adaptive and innate immunity in mice and rats through the differentiation and maturation of Th17 cells in the intestinal tract and production of immunoglobulin A (IgA). Although the role of SFB to induce antigen-specific Th17 cells in poultry is unknown, they may play an important role in modulating the immune response in the intestinal tract to promote resistance against some infectious diseases and promote food-safety. Many vertebrate intestines (such as mice, rats, chickens, humans, and turkeys) harbor commensal organisms named segmented filamentous bacteria (SFB) that bind specifically to the host intestinal epithelium. The role of SFB in Th17 cell production was initially demonstrated when mice were inoculated with mouse, rat, and human microbiota containing bacterial spores similar to that of the genus Clostridium. Colonization and distribution of segmented filamentous bacteria (SFB) in chicken gastrointestinal tract and their relationship with host immunity	./cache/cord-262682-gsvswr7v.txt	./txt/cord-262682-gsvswr7v.txt