id author title date pages extension mime words sentences flesch summary cache txt cord-026880-i45okohf Hartigan, Ashlie Transcriptome of Sphaerospora molnari (Cnidaria, Myxosporea) blood stages provides proteolytic arsenal as potential therapeutic targets against sphaerosporosis in common carp 2020-06-16 .txt text/plain 8217 402 47 title: Transcriptome of Sphaerospora molnari (Cnidaria, Myxosporea) blood stages provides proteolytic arsenal as potential therapeutic targets against sphaerosporosis in common carp Myxozoans are parasitic cnidarians that are important pathogens to both wild and cultured fish populations and yet there are no drug targets specified for this group and limited proteolytic studies to examine activity or function of selected proteins [9, 10] . vulgaris isoforms contained a transmembrane domain and a high homology to DPPIVs rather than POPs. We then examined the expression of eight key proteases in blood stages compared to spore forming gill stages by qPCR and also in silico expression (TPM). The divergence in sequence identity from their host, their expression in both blood and gill stages and their similarity to proteases that have been successfully blocked in such assays are all good evidence that these could be the first drug targets for S. ./cache/cord-026880-i45okohf.txt ./txt/cord-026880-i45okohf.txt