id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-014397-7b88ycv8	Gavora, JS	Resistance of livestock to viruses: mechanisms and strategies for genetic engineering	1996-12-15		.txt	text/plain	11583	528	41	Thus introduction of new mechanisms of disease resistance in livestock by gene transfer may be viewed as a logical continuation of the creative influence of humans on the evolution of farm animals and birds that could benefit mankind by improvements in food safety and production efficiency. As background for the discussion of the subject, the article deals briefly with coevolution of hosts and parasites and principal elements of virus-host interactions, and reviews past improvement of disease resistance in plants and livestock by conventional breeding and genetic engineering, as well as the potential 'biological cost' of genetic manipulation. Basic understanding of the parallel evolution of viruses and their hosts provides a useful starting point for the consideration of strategies for genetic engineering of new mechanisms of resistance. Genetic engineering strategies that prevent entry of viruses into host cells would be effective against all three types of viral infection.	./cache/cord-014397-7b88ycv8.txt	./txt/cord-014397-7b88ycv8.txt