"/home/eric/dead.letter" 14/486 Summary of your 'study carrel' ============================== This is a summary of your Distant Reader 'study carrel'. The Distant Reader harvested & cached your content into a collection/corpus. It then applied sets of natural language processing and text mining against the collection. The results of this process was reduced to a database file -- a 'study carrel'. The study carrel can then be queried, thus bringing light specific characteristics for your collection. These characteristics can help you summarize the collection as well as enumerate things you might want to investigate more closely. This report is a terse narrative report, and when processing is complete you will be linked to a more complete narrative report. Eric Lease Morgan Number of items in the collection; 'How big is my corpus?' ---------------------------------------------------------- 138 Average length of all items measured in words; "More or less, how big is each item?" ------------------------------------------------------------------------------------ 4874 Average readability score of all items (0 = difficult; 100 = easy) ------------------------------------------------------------------ 48 Top 50 statistically significant keywords; "What is my collection about?" ------------------------------------------------------------------------- 70 hospital 68 patient 68 Hospital 51 study 46 result 36 method 34 conclusion 34 University 28 group 21 ICU 17 cell 17 PCR 15 year 15 high 15 day 15 case 15 COVID-19 14 Care 13 introduction 13 dna 13 January 12 treatment 12 Intensive 11 level 11 Medical 10 mortality 10 disease 10 ARDS 9 infection 9 HIV 9 APACHE 9 AKI 8 sofa 8 SARS 8 HCV 8 Department 8 Center 8 Background 7 test 7 child 7 blood 7 VAP 7 RNA 7 MRI 7 Health 7 HLA 7 China 7 BMI 6 surgery 6 score Top 50 lemmatized nouns; "What is discussed?" --------------------------------------------- 76639 patient 67548 % 23587 study 21204 result 20458 cell 20026 group 17131 blood 16240 case 15875 method 14321 year 13829 day 12999 treatment 12232 p 12153 conclusion 11992 level 11244 time 10972 hospital 10926 disease 10145 age 9011 analysis 8784 risk 8709 datum 8269 rate 8263 donor 7704 month 7379 infection 7147 therapy 7134 control 7132 outcome 6785 care 6673 effect 6549 child 6534 factor 6307 expression 6204 mortality 6119 system 6118 test 6042 diagnosis 6024 surgery 5851 difference 5832 transfusion 5689 sample 5628 number 5580 use 5434 type 5281 tumor 5213 score 5155 period 5013 complication 4926 response Top 50 proper nouns; "What are the names of persons or places?" -------------------------------------------------------------- 6152 ICU 3817 Hospital 3201 University 3194 mg 3147 CT 3077 HSCT 2855 C 2351 II 2107 T 1972 CI 1916 CF 1906 A 1808 ED 1799 B 1792 ± 1680 PCR 1652 L 1634 M 1591 RBC 1586 GVHD 1544 Background 1508 Medical 1450 kg 1374 . 1360 CFTR 1335 Department 1301 IV 1296 AE 1291 HBV 1286 HCV 1279 S 1262 D 1235 Group 1223 S. 1206 HLA 1204 January 1199 MRI 1198 Care 1154 Health 1140 Center 1115 BMI 1105 - 1096 M. 1084 G 1060 Medicine 1054 CMV 1053 Objective 1005 HIV 991 Case 940 C. Top 50 personal pronouns nouns; "To whom are things referred?" ------------------------------------------------------------- 23266 we 9773 it 3699 they 2597 them 1973 he 1940 i 1681 she 579 us 244 you 213 one 166 itself 134 themselves 74 him 69 her 64 me 31 himself 16 ourselves 11 igg4 10 mg 9 his 8 ours 8 iga1 8 herself 7 myself 6 p210bcr 5 theirs 5 oneself 5 itma 5 em 4 yourself 4 hmsh2 3 s 3 pbp 3 imagej 3 igfbp2 3 hent1 2 thee 2 t2dm 2 rrt 2 ncs-4 2 mrnas 2 incmynsz 2 in-111-octreotide 2 i- 2 esat-6 2 cgvh 1 ≥65 1 ≥25 1 −5 1 α1-pdx Top 50 lemmatized verbs; "What do things do?" --------------------------------------------- 250246 be 38605 have 21315 use 11446 show 11057 include 10413 perform 9679 compare 9577 increase 8351 associate 7517 do 7464 follow 6551 evaluate 6405 find 6377 receive 6087 identify 5813 report 5560 treat 5273 base 5149 present 5102 determine 5070 develop 4991 assess 4905 reduce 4693 undergo 4521 observe 4243 require 4204 improve 4134 relate 4086 measure 3995 provide 3776 suggest 3761 detect 3744 decrease 3541 obtain 3439 analyze 3396 aim 3281 consider 3212 demonstrate 3208 collect 3201 remain 3164 occur 3115 accord 3033 investigate 2980 need 2977 study 2925 reveal 2900 make 2799 give 2771 lead 2725 diagnose Top 50 lemmatized adjectives and adverbs; "How are things described?" --------------------------------------------------------------------- 17701 - 17221 not 15332 high 9898 clinical 9291 low 8616 more 8247 significant 7699 also 7008 well 6836 other 6559 only 6396 significantly 6154 positive 6064 first 5995 most 5828 non 5711 however 5303 respectively 5279 acute 5060 mean 4912 severe 4843 different 4716 old 4583 renal 4504 normal 4473 median 4448 early 4256 medical 4125 anti 4060 negative 3882 surgical 3785 such 3748 as 3486 specific 3476 common 3411 primary 3391 total 3291 patient 3279 further 3254 new 3243 chronic 3189 long 3066 large 3021 important 2946 less 2944 post 2918 respiratory 2801 overall 2654 small 2644 good Top 50 lemmatized superlative adjectives; "How are things described to the extreme?" ------------------------------------------------------------------------- 1288 most 894 least 837 good 760 high 749 Most 311 low 227 large 179 great 118 bad 115 common 93 strong 67 late 53 big 42 young 39 long 37 early 36 old 28 small 28 close 25 safe 25 near 20 short 15 poor 13 -t 12 fast 11 easy 10 p=0.016 10 new 9 weak 8 deep 6 Least 5 slight 5 severe 5 hot 5 fresh 5 busy 4 steep 4 sick 4 rare 4 quick 4 postsurgery 4 narrow 4 -E 3 wide 3 thick 3 northernmost 3 dense 3 clear 3 E(13.4 3 226/303 Top 50 lemmatized superlative adverbs; "How do things do to the extreme?" ------------------------------------------------------------------------ 4707 most 858 least 96 well 9 highest 5 lowest 3 youngest 3 worst 3 hard 2 long 2 fast 1 ® 1 themost 1 shortest 1 s2&3 1 micrometre 1 low(150 1 freshest 1 fewest 1 cm² 1 cfdna 1 astrocytomas 1 -tug 1 -sc1.3 1 -chest Top 50 Internet domains; "What Webbed places are alluded to in this corpus?" ---------------------------------------------------------------------------- 23 doi.org 5 bit.ly 3 www.nrlqa.net 3 www.mederrors.com. 3 www.hsph.harvard.edu 3 orcid.org 3 creativecommons.org 2 www.biomedcentral.com 1 zha 1 www.who.int 1 www.textcheck.com 1 www.surveymonkey.com 1 www.shef.ac.uk 1 www.real-score.org 1 www.rcsb.org 1 www.nice.org.uk 1 www.ncbi.nlm.nih.gov 1 www.isbtweb.org 1 www.ihi.org 1 www.finngen.fi 1 www.expertmed.it 1 www.compbio.dundee.ac.uk 1 www.colorectaleducation.com 1 www.bundles.com.br 1 vakser.compbio.ku.edu 1 va 1 training.fema 1 structure.biol.ucy.ac.cy 1 stopcorona.tn.gov.in 1 stir.sourceforge.net 1 sparks-lab.org 1 servicesn.mbi.ucla.edu 1 robetta.bakerlab.org 1 raptorx.uchicago.edu 1 protein.ict.ac.cn 1 prosa.services.came.sb 1 predictprotein.org 1 nihserver.mbi.ucla.edu 1 jkms.org 1 flexdex.com 1 eufrattool.ecdc.europa.eu 1 er1.org 1 doi 1 clinicaltrials.gov 1 bit 1 bcb.med.usherbrooke.ca 1 atgme.org 1 apps.dtic.mil 1 algo.grismoir.com 1 clinicaltrials.gov Top 50 URLs; "What is hyperlinked from this corpus?" ---------------------------------------------------- 6 http://doi.org/10.1101/2020.10.29.20222430 4 http://doi.org/10.1101/2020.04 3 http://www.nrlqa.net 3 http://www.mederrors.com. 3 http://www.hsph.harvard.edu/cearegistry 3 http://doi.org/10 2 http://creativecommons.org/licenses/by/4.0/ 1 http://zha 1 http://www.who.int/medicines/access/controlled-substances/ 1 http://www.textcheck.com/certificate/ixNwjT 1 http://www.surveymonkey.com 1 http://www.shef.ac.uk/FRAX 1 http://www.real-score.org 1 http://www.rcsb.org/structure/3nvq 1 http://www.nice.org.uk/guidance/ 1 http://www.ncbi.nlm.nih.gov/igblast/ 1 http://www.isbtweb.org/working-parties/red-cell-immunogenetics-and-bloodgroup-terminology/ 1 http://www.ihi.org 1 http://www.finngen.fi/ 1 http://www.expertmed.it 1 http://www.compbio.dundee.ac.uk/jpred4/ 1 http://www.colorectaleducation.com/ 1 http://www.bundles.com.br 1 http://www.biomedcentral.com/1472-6963/9/94/prepub 1 http://www.biomedcentral.com/1471-2458/8/319/pre 1 http://vakser.compbio.ku.edu/resources/gramm/grammx/ 1 http://va 1 http://training.fema 1 http://structure.biol.ucy.ac.cy/latcom.html 1 http://stopcorona.tn.gov.in/ 1 http://stir.sourceforge.net 1 http://sparks-lab.org/server/SPIDER2/ 1 http://servicesn.mbi.ucla.edu/Verify3D/ 1 http://robetta.bakerlab.org/submit 1 http://raptorx.uchicago.edu 1 http://protein.ict.ac.cn/TreeThreader/ 1 http://prosa.services.came.sb 1 http://predictprotein.org 1 http://orcid.org/0000-0002-8374-0260 1 http://orcid.org/0000-0002-5246-0290 1 http://orcid.org/0000-0001-9508-0995 1 http://nihserver.mbi.ucla.edu/RACC/ 1 http://jkms.org 1 http://flexdex.com/register-for-training 1 http://eufrattool.ecdc.europa.eu/ 1 http://er1.org 1 http://doi.org/10.3346/jkms.2020.35.e332 1 http://doi.org/10.1371/journal.pone.0241169.t004 1 http://doi.org/10.1371/journal.pone.0241169.t003 1 http://doi.org/10.1371/journal.pone.0241169.t002 Top 50 email addresses; "Who are you gonna call?" ------------------------------------------------- 4 snarayan@childrensnational.org 3 nkadom@childrensnational.org 3 drvikasmenghani@gmail.com 3 dristuna@yahoo.com 2 yacine001@yahoo.fr 2 usha.nagaraj@osumc.edu 2 suraj.serai@cchmc.org 2 oussamajaoued@gmail.com 2 mjl1213@yumc.yonsei.ac.kr 2 kurianj@email.chop.edu 2 kim.cecil@cchmc.org 2 jaraque@georgiahealth.edu 2 eiblanco74@gmail.com 2 e.nhihuynh@gmail.com 2 benhamzasabah5@gmail.com 2 andrea.doria@sickkids.ca 2 amitsensation@yahoo.co.in 2 alokjaju@gmail.com 2 ahmad.aouthmany@utoledo.edu 2 henrietta.rosenberg@mountsinai.org 1 victorrivneac@yahoo.com 1 tsai@childrens.harvard.edu 1 tkelly@chw.org 1 teresaliang86@gmail.com 1 taylorchung12@gmail.com 1 tanyasupakul@yahoo.com 1 swestra@partners.org 1 sumitsingh78@yahoo.com 1 sthawai2@jhmi.edu 1 states@email.chop.edu 1 stanescu@u.washington.edu 1 spalasis@yahoo.com 1 sophie.jacquier@chr-orleans.fr 1 shilpavhegde@gmail.com 1 shawn.parnell@seattlechildrens.org 1 scorpion68kd@yahoo.com 1 schmitzk@ohsu.edu 1 sblumer@montefiore.org 1 samia.ayed@yahoo.fr 1 sadatsouhila@hotmail.fr 1 rxkrishn@texaschildrens.org 1 run4boston@gmail.com 1 rudyavar@gwmail.gwu.edu 1 rubioeva@yahoo.com 1 ramy.jalbout@yahoo.com 1 rami.nachabe@philips.com 1 radhakrp@ucmail.uc.edu 1 pkhanna@uw.edu 1 paul.jaubert@gmail.com 1 painvinbe@gmail.com Top 50 positive assertions; "What sentences are in the shape of noun-verb-noun?" ------------------------------------------------------------------------------- 111 patients did not 95 levels were significantly 80 % were male 66 patients were male 56 % were female 53 patients were not 52 data are available 48 patients are alive 42 patients were randomly 41 patient did not 38 patients undergoing cardiac 36 patients had normal 35 studies are necessary 34 cells were positive 34 group was significantly 34 patients were more 33 groups were similar 33 patients do not 33 patients were also 32 patients undergoing elective 32 patients were eligible 31 % did not 31 patients were alive 30 levels were higher 29 groups did not 29 patients undergoing hsct 29 patients were female 28 % were males 28 patients undergoing laparoscopic 27 data were available 26 group were significantly 26 groups were comparable 26 levels were not 26 patients undergoing surgery 26 rate was significantly 25 levels did not 25 patients are not 24 patients had positive 24 patients were males 24 rate was higher 23 analysis did not 23 patients are often 23 patients underwent laparoscopic 23 patients were then 23 results were not 22 cells were also 22 patients was significantly 21 group did not 21 patients had higher 21 patients had more Top 50 negative assertions; "What sentences are in the shape of noun-verb-no|not-noun?" --------------------------------------------------------------------------------------- 6 levels were not significantly 6 results were not statistically 5 groups was not statistically 5 levels were not different 5 patient had no history 5 treatment did not significantly 4 cells are not available 4 groups did not significantly 4 groups showed no significant 4 patients is not clear 4 patients were not able 3 % had no effect 3 analysis showed no difference 3 blood was not less 3 cell was not present 3 cells do not consistently 3 cells showed no change 3 data are not available 3 donor is not available 3 donors had no major 3 donors have no intention 3 group was not significant 3 groups has not statistical 3 groups was not significantly 3 groups were not significant 3 groups were not significantly 3 groups were not statistically 3 levels are not relevant 3 methods are not sufficiently 3 months had no statistically 3 outcome was not possible 3 patient had no significant 3 patient had no transfusion 3 patient was not essentially 3 patients are not able 3 patients had no history 3 patients had no previous 3 patients were not evaluable 3 rate was not different 3 rates were not significantly 3 results show no evidence 3 results showed no discrepancies 3 treatment is not always 3 treatment is not available 2 analysis showed no significant 2 cases had no residual 2 cases were not significantly 2 cells had no effect 2 cells was not significantly 2 data were not available A rudimentary bibliography -------------------------- id = cord-323596-dh7oh54z author = Advani, Sonali D. title = Assessing severe acute respiratory coronavirus virus 2 (SARS-CoV-2) preparedness in US community hospitals: A forgotten entity date = 2020-10-07 keywords = SARS; hospital summary = Several differences in hospital preparedness for SARS-CoV-2 emerged with respect to personal protective equipment conservation strategies, protocols related to testing, universal masking, and restarting elective procedures. Hence, we conducted a cross-sectional survey of SARS-CoV-2 preparedness among community hospitals in southeastern United States. The survey included 13 questions related to PPE availability, crisis capacity strategies to extend and reuse PPE, policies related to restarting surgeries, testing prior to elective surgery and prior to transfer to extended care facilities, universal masking, and daily screening of hospital staff. In addition, 80% of hospitals reported an adequate supply of N95 respirators, face shields, and googles, likely due to use of crisis capacity strategies to extend, reuse, and reprocess these PPE. We found several differences in community hospital preparedness for SARS-CoV-2 with respect to type of conservation strategies used to preserve PPE, protocols related to testing, masking, and restarting elective procedures. doi = 10.1017/ice.2020.1238 id = cord-017534-0ai8chbu author = Andersen, Bjørg Marit title = Background Information: Isolation Routines date = 2018-09-25 keywords = Norway; hospital; infection; isolation; patient summary = There is an increased need of isolates for patients with infections, especially due to pulmonary tuberculosis, MRSA, VRE, Clostridium difficile (CD), multiresistant gram-negative bacteria and other "multidrug-resistant organisms" (MDRO) [23, 24, 36, 37, [48] [49] [50] [51] . In 2009, a European investigation was done as regards the number of "high-level isolation rooms" (HIRs), i.e. airborne infection isolation units with negative pressure (not defined) with at least 6 air changes per hour and sluice (anteroom) [61] . CDC defines contact isolation, using gown and gloves when in contact with patients infected with resistant bacteria like MRSA and other MDROs (multidrug-resistant organisms), and single rooms are recommended [19] . Spread of pathogenic infectious agents through the air and droplets requires a defined negative pressure ventilation isolate and a system which reduces airborne infection in the patient''s room. doi = 10.1007/978-3-319-99921-0_21 id = cord-350261-7lkcdisr author = Asirvatham, Edwin Sam title = Who is dying from COVID-19 and when? An Analysis of fatalities in Tamil Nadu, India date = 2020-10-03 keywords = COVID-19; death; hospital summary = Understanding the demographic and clinical characteristics of deceased COVID-19 patients; and estimation of time-interval between symptom onset, hospital admission and death could inform public health interventions focusing on preventing mortality due to COVID-19. This study aims to understand the demographic and clinical characteristics of deceased COVID-19 patients; and estimate the time-interval between symptom onset, hospital admission and death, which could inform public health interventions focusing on preventing mortality due to COVID-19. Our study analysed the individual death summaries, and described the demographic and clinical characteristics of deceased COVID-19 patients; and estimated the time intervals between symptoms onset to hospital admission and death, which are critical for developing context and geographicspecific public health interventions focusing on reducing the mortality. doi = 10.1016/j.cegh.2020.09.010 id = cord-351918-pu7i1jfe author = Baek, Yae Jee title = A mathematical model of COVID-19 transmission in a tertiary hospital and assessment of the effects of different intervention strategies date = 2020-10-26 keywords = COVID-19; hospital summary = The effects of different intervention strategies such as front door screening, quarantine unit for newly admitted patients, early testing of suspected infected people, and personal protective equipment for both medical staff and visitors were evaluated. The model suggested that the early testing (within eight hours) of infected cases and monitoring the quarantine ward for newly hospitalized patients are effective measures for decreasing the incidence of COVID-19 within a hospital (81.3% and 70% decrease of number of incident cases, respectively, during 60 days). Setting the population vector η as the number of staff, and the stabilized number of inflow and outflow to each department for visitors, we construct the WAIFW matrix, W, by assuming that it is proportional to the contact rate matrix [8, 9] : The diagram for the SEIR (susceptible-exposed-infectious-recovered) model with compartments of doctor, nurse, patient, and caregiver. doi = 10.1371/journal.pone.0241169 id = cord-346866-90w4zepx author = Bassareo, Pier Paolo title = Learning from the past in the COVID-19 era: rediscovery of quarantine, previous pandemics, origin of hospitals and national healthcare systems, and ethics in medicine date = 2020-08-20 keywords = covid-19; disease; hospital; principle; quarantine summary = title: Learning from the past in the COVID-19 era: rediscovery of quarantine, previous pandemics, origin of hospitals and national healthcare systems, and ethics in medicine In that book, the procedure of separating infected from healthy people to prevent leprosy from spreading, according to Mosaic Law was described, (if the shiny spot on the skin is white but does not appear to be more than skin deep and the hair in it has not turned white, the priest is to isolate the affected person for seven days. 15 Since disease was considered as a divine punishment for sinners, the biblical 40-day period of purification had crossed over into health practices and the term ''quarantine'' had great symbolic and religious significance to medieval Christians. 19 20 According to current knowledge, the bubonic plague has an averaged 37-day period from infection to death; therefore, the European quarantines would be highly successful in determining the health of crews from potential trading and supply ships. doi = 10.1136/postgradmedj-2020-138370 id = cord-016601-gp259urb author = Bonadonna, Lucia title = Analysis of Microorganisms in Hospital Environments and Potential Risks date = 2017-03-24 keywords = hospital; infection; patient summary = Hospital environments are characterized by high infective risk, firstly cause of the compromised immunologic conditions of the patients that make them vulnerable to bacterial, viral, parasitological and fungal opportunistic infections (D''Alessandro et al. The potential transmission of biological matter during surgery operations and medical treatments of infected individuals makes hospital environments strongly designated to become easily contaminated with spread of pathogens among patients (Baglioni and Capolongo 2002) . In addition, technological devices such as hydraulic, heating and air-conditioning systems may represent a potential source of bacteria, fungi (moulds), virus and other organisms if not adequately designed and submitted to a planned preventive maintenance. These difficulties are exacerbated in hospitals where the patient health status, the activities that take place and the potential spread of pathogenic biological agents increase the level of complexity respect to other indoor environments. doi = 10.1007/978-3-319-49160-8_5 id = cord-346276-1dcp05rd author = Bonfá, Eloisa title = How COVID-19 is changing rheumatology clinical practice date = 2020-11-02 keywords = COVID-19; Hospital; disease; patient summary = The emergence of COVID-19 in early 2020 led to unprecedented changes to rheumatology clinical practice worldwide, including the closure of research laboratories, the restructuring of hospitals and the rapid transition to virtual care. Abstract | The emergence of COVID-19 in early 2020 led to unprecedented changes to rheumatology clinical practice worldwide, including the closure of research laboratories, the restructuring of hospitals and the rapid transition to virtual care. Zhanguo Li. As a rheumatologist practicing at Peking University People''s Hospital, Beijing, the biggest challenge during the COVID-19 pandemic has been how to manage patients with rheumatic diseases remotely using online systems, social media platforms (such as WeChat) or telephone calls, because the patients simply could not physically attend the hospital. www.nature.com/nrrheum Zhanguo Li. To adapt to the totally unexpected changes to clinical practice, one option in my department of the People''s Hospital was to set up a consultant team consisting of 26 rheumatologists to provide medical service free to patients with rheumatic diseases, supported technically by an internet company. doi = 10.1038/s41584-020-00527-5 id = cord-318282-ocgfgx9r author = Boyce, John M title = Meticillin-resistant Staphylococcus aureus date = 2005-10-31 keywords = MRSA; Staphylococcus; USA; hospital; infection; patient summary = Measures recommended by the Society for Healthcare Epidemiology of America for controlling health-care-associated MRSA include the use of screening cultures to detect colonised patients, placing patients in private rooms or cohorting patients, wearing gloves for room entry, gowns for substantial contact with patients or their environment, and hand hygiene before and after patient contact. Further studies are necessary to establish the relative efficacy of control measures such as screening cultures, cohort nursing, increased staffing levels, and improved hand hygiene adherence rates in controlling transmission of MRSA in health-care facilities. Revised guidelines for the control of methicillin resistant Staphylococcus aureus infections in hospitals Comparison of community-and health care-associated methicillin-resistant Staphylococcus aureus infection Epidemiology of emerging methicillin-resistant Staphylococcus aureus (MRSA) in Denmark: a nationwide study in a country with low prevalence of MRSA infection Effectiveness of a hospitalwide selective screening programme for methicillin-resistant Staphylococcus aureus (MRSA) carriers at hospital admission to prevent hospital-acquired MRSA infections doi = 10.1016/s1473-3099(05)70243-7 id = cord-022076-zpn2h9mt author = Chaffee, Mary W. title = The Role of Hospitals in Disaster date = 2009-05-15 keywords = disaster; emergency; hospital; response summary = An effective hospital emergency management program guides the development and execution of activities that mitigate, prepare for, respond to, and recover from incidents that disrupt the normal provision of care. • Imagine the unimaginable: When flood waters rise in a community, when a tornado touches down and demolishes an elementary school, when a disgruntled hospital employee opens fire with an automatic weapon in the emergency department, when a passing train derails and spills toxic chemicals, or when a wildfire closes in, it is too late to update an old plan, train staff to respond effectively, check phone numbers, and stock disaster supplies. A comprehensive hospital emergency management program must address a number of critical elements to adequately protect patients and staff and permit the facility to continue to operate. 18 Hospitals must plan for providing mental health services to disaster victims but must also consider the needs-acute and long-term-of the hospital staff who attempt to respond to an overwhelming event. doi = 10.1016/b978-0-323-03253-7.50012-1 id = cord-333509-dnuakd6h author = Chan, Hui Yun title = Hospitals’ Liabilities in Times of Pandemic: Recalibrating the Legal Obligation to Provide Personal Protective Equipment to Healthcare Workers date = 2020-10-17 keywords = Health; NHS; PPE; healthcare; hospital; worker summary = Recent developments have witnessed strong responses from the public and healthcare workers, ranging from pursuing legal actions against the government or their employers (hospitals) for breaching their obligations of care towards employees to calling for a full public inquiry into pandemic management, including the status of the PPE stockpile. PPE under the Regulations means "all equip-ment…intended to be worn or held by a person at work and which protects the person against one or more risks to that person''s health or safety, and any addition or accessory designed to meet that objective." 29 Consequently, PPE in the hospital context is broad enough to include all equipment that protect healthcare workers from infectious particles arising from aerosol generating procedures, ventilators, respirators or testing facilities with high concentrations of droplets or airborne diseases. Imposing the duty to provide PPE is therefore central in ensuring healthcare workers are protected from the risks of infection and to realise the aim of delivering patient-centred care to the public. doi = 10.1007/s10991-020-09270-z id = cord-305353-81qc0iur author = Chang, I-Chiu title = Factors affecting cross-hospital exchange of Electronic Medical Records date = 2009-03-31 keywords = EMR; exchange; hospital summary = Our study combined transaction cost and sociological perspectives to identify factors that affect a hospitals'' willingness to implement EMR exchange. Our study combined transaction cost and sociological perspectives to identify factors that affect a hospitals'' willingness to implement EMR exchange. Our findings indicated that the model was valuable and determined which factors influenced the decision to implement EMR exchange at these hospitals (perceived benefits, uncertainty, influence, and reciprocal investments). Our findings indicated that the model was valuable and determined which factors influenced the decision to implement EMR exchange at these hospitals (perceived benefits, uncertainty, influence, and reciprocal investments). Therefore, in our model both TCT and SET variables were included as independent variables and weighted equally to provide a complementary theoretical foundation for studying the hospital decision to adopt EMR exchange. Therefore, EMR exchange not only integrates the records of patients but also helps adopting hospitals increase the quality of health care while reducing costs. doi = 10.1016/j.im.2008.12.004 id = cord-184194-zdxebonv author = Chen, Lichin title = Using Deep Learning and Explainable Artificial Intelligence in Patients'' Choices of Hospital Levels date = 2020-06-24 keywords = datum; hospital; patient; provider summary = This study used nationwide insurance data, accumulated possible features discussed in existing literature, and used a deep neural network to predict the patients choices of hospital levels. Focusing on the hospital levels of the patients'' choices, this study used explainable artificial intelligence (XAI) methods to interpret the effecting features for the general public and individuals. According to a public opinion poll conducted in 2019 [35] , although 85.3% of the respondents agreed that for a mild condition the patient should go to the primary care service nearby instead of tertiary hospitals, 70% considered institutes with higher levels to possess better professional skills, and 49% expressed having confidence in determining the severity of their own condition. According to our result, three features could interpret the majority of patients'' choices of hospital levels: the MFPC, LFPC, and physician density. doi = nan id = cord-262150-j72jbohi author = Cheng, Chun-Hung title = RFID analytics for hospital ward management date = 2015-10-23 keywords = RFID; hospital; patient; ward summary = With a prototype developed based on the architecture of this platform, a pilot study was then conducted in two medical wards of the intensive care unit of one of the largest public general hospitals in Hong Kong to demonstrate the feasibility of its practical use. Here, we present the concept and architecture of an RFID-enabled platform for hospital ward management, which aims to provide inpatient care of higher quality, reduce patient risk, and optimize operations. After the outbreak of SARS, a project team from the CUHK considered the feasibility of using RFID technology to enable traceability for person-to-person physical contacts in order to provide immediate response to the widespread of infectious diseases and better risk management within hospital wards. In this paper, we presented an active RFID-enabled platform to keep track of the locations of patients, ward staff, and medical equipment, for hospital ward management. doi = 10.1007/s10696-015-9230-6 id = cord-290119-2yao5a80 author = Chiang, Wen-Chu title = EMS in Taiwan: Past, present, and future() date = 2008-12-06 keywords = EMS; Taiwan; hospital summary = The year 1995 marked the beginning of modern EMS in Taiwan when a lot of important concepts of EMS were put into legislation, The Emergency Medical Service Act. The law designated pre-hospital care as a function of fire administration at the central and local level. Over the last eight years, Taiwan''s EMS has undergone rapid development, including the implementation of off-line medical direction, establishment of national disaster response teams, and the introduction of automatic external defibrillators (AED) by EMTs. enabling the EMS to provide fire service based advanced life support (ALS). Physicians on the medical consulting committees (required by law) are responsible for the standards of patient care, including establishment of pre-hospital medical protocols and assistance in education of EMTs. However, a lack of specific tasking and full-time positions in the fire department for medical directors has resulted in the medical oversight remaining incomplete in terms of protocol revision, quality assurance, system design, and direct medical oversight. doi = 10.1016/j.resuscitation.2008.10.010 id = cord-314449-ukqux772 author = Curtis, L.T. title = Prevention of hospital-acquired infections: review of non-pharmacological interventions date = 2008-06-02 keywords = MRSA; hospital; infection; patient; study summary = Interventions such as proper hand and surface cleaning, better nutrition, sufficient numbers of nurses, better ventilator management, use of coated urinary and central venous catheters and use of high-efficiency particulate air (HEPA) filters have all been associated with significantly lower nosocomial infection rates. This review is not exhaustive and will not attempt mathematical data analysis but will examine recent research that examines non-pharmacological interventions for reducing HAIs. It will also include a brief description of the morbidity, mortality and medical costs associated with nosocomial infections, along with a brief discussion of the routes by which HAIs spread. Many terms were used in the literature searches including nosocomial, hospital acquired, MRSA (meticillin-resistant Staphylococcus aureus), staphyloccoccus, streptococcus, VRE (vancomycinresistant enterococcus), Clostridium difficile, legionella, klebsiella, tuberculosis, airborne infection, waterborne infection, hand washing, hospital cleaning, urinary catheters, central catheters, haemodialysis, ultraviolet light, HEPA (high-efficiency particulate air) filtration and many others. doi = 10.1016/j.jhin.2008.03.018 id = cord-339835-ze9ay2rm author = Daphna-Tekoah, Shir title = Listening to Hospital Personnel’s Narratives during the COVID-19 Outbreak date = 2020-09-03 keywords = COVID-19; Guide; Listening; hospital; need summary = As a means to address the changing needs of our hospital''s HCWs, we conducted a narrative analysis study in the early stages of the covid-19 outbreak. By paying close attention the narratives of the hospital staff, we were able to address an additional aim, namely, to initiate the establishment of a data-based foundation for both immediate and future interventions, thereby expanding knowledge regarding the psychological mechanisms and strategies that front-line personnel use to cope with exposure to traumatic situations. Sharon, a nurse, summed up this opinion very succinctly as: "Corona-it is not extra work, it is completely different work." Against the background of this commonly held perspective, the third stage of the Listening Guide analytic technique nonetheless enabled us, the interviewers, to identify multiple voices that revealed different aspects of HCWs'' experiences and needs, including their attitudes towards the coronavirus pandemic, the staff and the hospital, and their own needs. doi = 10.3390/ijerph17176413 id = cord-353692-2zotqreu author = Dong, Fen title = Effect on Thromboprophylaxis among Hospitalized Patients Using a System-wide Multifaceted Quality Improvement Intervention: Rationale and Design for a Multicenter Cluster Randomized Clinical Trial in China date = 2020-05-07 keywords = VTE; hospital summary = title: Effect on Thromboprophylaxis among Hospitalized Patients Using a System-wide Multifaceted Quality Improvement Intervention: Rationale and Design for a Multicenter Cluster Randomized Clinical Trial in China Methods To facilitate implementation of guideline recommendations, we conduct a multicenter, adjudicator-blinded, cluster-randomized clinical trial, aiming to assess the effectiveness of a system-wide multifaceted quality improvement (QI) strategy on VTE prophylaxis improvement and thromboembolism reduction in clinical setting. In intervention group, hospitals receive the concept of appropriate in-hospital thromboprophylaxis plus a multifaceted QI which encompasses four components: (1) an electronic alert combining computer-based clinical decision support system and electronic reminders, (2) appropriate prophylaxis based on dynamic VTE and bleeding risk assessments, (3) periodical audit and interactive feedback on performance, (4) strengthened training and patient education. To better understand usual care in control group in this study, we will conduct a baseline survey in recruited hospitals before cluster randomization, collecting information on VTE and bleeding risk assessment, prophylactic approaches, initiating time for prophylaxis, etc. doi = 10.1016/j.ahj.2020.04.020 id = cord-342250-x5bzrpcu author = Faires, Meredith C title = The use of the temporal scan statistic to detect methicillin-resistant Staphylococcus aureus clusters in a community hospital date = 2014-07-08 keywords = MRSA; Staphylococcus; cluster; hospital summary = The objectives of this study were to investigate the utility of the temporal scan statistic for detecting MRSA clusters, validate clusters using molecular techniques and hospital records, and determine significant differences in the rate of MRSA cases using regression models. The objectives of this study were to investigate the utility of the temporal scan statistic for detecting MRSA clusters in a community hospital and to validate significant clusters using molecular techniques and hospital records concerning known MRSA outbreaks; and to determine if there were significant differences in the rate of MRSA infection and colonization cases by month, season, and year using regression models. Data pertaining to known MRSA outbreaks that occurred during the study period (e.g., start and end date, ward location, and number of patients involved) were collected from the hospital''s Infection Prevention and Control (IPC) department. doi = 10.1186/1471-2334-14-375 id = cord-343145-ptkw0csu author = Gilbert, Gwendolyn L. title = The politics and ethics of hospital infection prevention and control: a qualitative case study of senior clinicians’ perceptions of professional and cultural factors that influence doctors’ attitudes and practices in a large Australian hospital date = 2019-04-02 keywords = IPC; doctor; hospital; participant; practice summary = title: The politics and ethics of hospital infection prevention and control: a qualitative case study of senior clinicians'' perceptions of professional and cultural factors that influence doctors'' attitudes and practices in a large Australian hospital METHODS: This qualitative case study involved in-depth interviews with senior clinicians and clinician-managers/directors (16 doctors and 10 nurses) from a broad range of specialties, in a large Australian tertiary hospital, to explore their perceptions of professional and cultural factors that influence doctors'' IPC practices, using thematic analysis of data. RESULTS: Professional/clinical autonomy; leadership and role modelling; uncertainty about the importance of HAIs and doctors'' responsibilities for preventing them; and lack of clarity about senior consultants'' obligations emerged as major themes. CONCLUSIONS: Failure of healthcare and professional organisations to address doctors'' poor IPC practices and unprofessional behaviour, more generally, threatens patient safety and staff morale and undermines efforts to minimise the risks of dangerous nosocomial infection. doi = 10.1186/s12913-019-4044-y id = cord-022075-bbae2nam author = Gougelet, Robert M. title = Disaster Mitigation date = 2009-05-15 keywords = Health; community; hospital; mitigation summary = • The ability to maintain function • Building design • Locating buildings outside of hazard zones (e.g., flood plains) • Essential building utilities • Protection of building contents • Insurance • Public education • Surveillance • Warning • Evacuation It is of critical importance that emergency planners incorporate the basic elements of mitigation and have the authority and resources to incorporate these changes into their organization/facility/community. • Forming effective community-based partnerships for hazard mitigation purposes • Implementing effective hazard mitigation measures that reduce the potential damage from natural disasters • Ensuring continued functionality of critical services • Leveraging additional nonfederal resources in meeting natural disaster resistance goals • Making commitments to long-term hazard mitigation efforts to be applied to new and existing structures This important legislation sought to identify and assess the risks to states and local governments (including Indian tribes) from natural disasters. doi = 10.1016/b978-0-323-03253-7.50028-5 id = cord-292544-m7jyydf1 author = Grau-Pujol, Berta title = Pre-exposure prophylaxis with hydroxychloroquine for high-risk healthcare workers during the COVID-19 pandemic: A structured summary of a study protocol for a multicentre, double-blind randomized controlled trial date = 2020-07-29 keywords = COVID-19; Hospital; SARS; study summary = OBJECTIVES: The aim of this study is to assess the efficacy of the use of pre-exposure prophylaxis (PrEP) with hydroxychloroquine against placebo in healthcare workers with high risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in reducing their risk of coronavirus disease 2019 (COVID-19) disease during an epidemic period. As secondary endpoints, we will obtain: i) the SARS-CoV-2 seroconversion in the PrEP group compared to placebo during the 6 months of follow-up in healthcare workers with negative serology at day 0; ii) the occurrence of any adverse event related with hydroxychloroquine treatment; iii) the incidence of SARS-CoV-2 infection and COVID-19 among healthcare workers in the non-PrEP group, among the total of healthcare workers included in the non-PrEP group during the study period; iv) the risk ratio for the different clinical, analytical and microbiological conditions to develop COVID-19; v) a repository of serum samples obtained from healthcare workers confirmed COVID-19 cases for future research on blood markers to predict SARS-CoV-2 infection. doi = 10.1186/s13063-020-04621-7 id = cord-286523-4ip8er0h author = Grippaudo, Francesca Romana title = The impact of COVID-19 in plastic surgery departments: a comparative retrospective study in a COVID-19 and in a non-COVID-19 hospital date = 2020-08-26 keywords = covid-19; hospital; surgery summary = Most of the Italian plastic surgery wards faced a reduction in beds and theatres to enable hospitals to free up healthcare staff to provide medical care for patients in other areas, given the need for a change in work organization to comply with limited outpatient clinic activities and reduced theatre availability for all hospitalization typologies and to cope with new pre-hospitalization modalities to screen up COVID-19 positive patients among the ones scheduled for surgery. Are you in contact with anyone who has been confirmed to be COVID-19 posiƟve, or that are in quaranƟne for exposure to Study data shows the effects of the consequence of cancellation of plastic surgery elective surgeries in both hospitals during the lockdown, when the operating theatre was available only for such urgent procedures as melanoma or melanoma and SLNB removal or for post-traumatic reconstruction in PU1. doi = 10.1007/s00238-020-01725-w id = cord-287032-ftkoxzz4 author = Grossman, Valerie Aarne title = Catastrophe In Radiology: Considerations Beyond Common Emergencies date = 2020-05-13 keywords = Radiology; disaster; event; hospital; plan summary = ♦ Incident command centers must be deployable and not fixed ♦ Organizations must keep up-to-date phone lists (employees, local business, vendors, fuel companies, utility companies, medical equipment companies, etc.) ♦ Portable wi-fi units can be used if IT down or power outages occur ♦ Satellite telephones, wireless radios, amateur radios, and other forms of communication may be used if cellular telephones and/or landlines fail ♦ Organizational leadership must be visible around the building, calm, optimistic, and ready to respond to issues (Bluth, 2007) ◊ Communication must be honest, transparent, and frequent in order to counter the spread of inaccurate rumors and contain mounting fear among staff, patients, visitors (Jones, 2017) ♦ When calling for emergency assistance ("911") or reporting suspicious activity, essential facts should include: Gray, 2007; DOH, 2011) patient transport to/from radiology (Berger, 2016) ♦ If the disaster is an approaching storm, all studies should be dictated, rooms stocked with supplies, phone numbers updated, disaster management plan reviewed with team ◊ Extra staff should be called in ◊ Consider moving some portable equipment to essential upper floors (in case elevators fail during the storm event). doi = 10.1016/j.jradnu.2020.05.002 id = cord-337889-90q4py0j author = Guan, Wei-jie title = Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis date = 2020-03-26 keywords = County; Hospital; People summary = After adjusting for age and smoking status, COPD [hazards ratio (HR) 2.681, 95% confidence interval (95%CI) 1.424–5.048], diabetes (HR 1.59, 95%CI 1.03–2.45), hypertension (HR 1.58, 95%CI 1.07–2.32) and malignancy (HR 3.50, 95%CI 1.60–7.64) were risk factors of reaching to the composite endpoints. Studies that address these limitations is needed to explore for the factors underlying the adverse impact of Our objective was to evaluate the risk of serious adverse outcomes in patients with Covid-19 by stratification according to the number and type of comorbidities, thus unraveling the sub-populations with poorer prognosis. These findings have provided further objective evidence, with a large sample size and extensive coverage of the geographic regions across China, to take into account baseline comorbid diseases in the comprehensive risk assessment of prognosis among patients with Covid-19 on hospital admission. Our findings suggested that, similar with other severe acute respiratory outbreaks, comorbidities such as COPD, diabetes, hypertension and malignancy predisposed to adverse clinical outcomes in patients with Covid-19. doi = 10.1183/13993003.00547-2020 id = cord-272971-9luzvzsu author = Guo, Hainan title = Hong Kong Hospital Authority resource efficiency evaluation: Via a novel DEA-Malmquist model and Tobit regression model date = 2017-09-08 keywords = DEA; GSBUP; HKHA; Hospital summary = In recent decades, Hong Kong Hospital Authority (HKHA) has been making efforts to improve the healthcare services, but there still exist some problems like unfair resource allocation and poor management, as reported by the Hong Kong medical legislative committee. Regarding the multiple inputs and outputs, Data Envelopment Analysis (DEA) has been recognized as an effective nonparametric model to assess the relative efficiencies of a set of decision-making units (DMUs) [3] . In this section, we first analyze the HKHA data, and then discuss the measurement results of hospital efficiency in HK from 2000 to 2013 by applying Malmquist index based on GSBUP-DEA. The high crude mortality rates can be due to the facts that: (i) Pok Oi Hospital provides the elderly care for the people whose health condition and dependency level are beyond the coping We use the data in 2013 as an example to illustrate the statistical characteristics of the specific input-output factors. doi = 10.1371/journal.pone.0184211 id = cord-329152-1ixylnny author = Gupta, Shaili title = Hospital preparedness for COVID-19 pandemic: experience from department of medicine at Veterans Affairs Connecticut Healthcare System date = 2020-04-24 keywords = COVID-19; hospital; patient summary = We share our hospital-wide rapid preparedness and response to COVID-19 to help provide information to other healthcare systems globally. Response to pandemic is a multi-disciplinary team effort with efficient leadership that meets several times daily to work at a quick pace in order to make effective implementation of preparatory measures before the actual arrival of the first infected patients, followed by a continuity of the same diligence to ensure modifications in plans as needed and addressing new demands as they arise. Additionally she created protocols for well-informed care of patients, enhanced the education and protective measures for HCWs including residency trainees, developed a clinical algorithm to guide judicious testing, and participated in COVID-19 treatment group meetings at other institutions to help create or modify local treatment algorithms. doi = 10.1080/00325481.2020.1761668 id = cord-004540-2b1vjhgn author = Hick, John L. title = Chapter 2. Surge capacity and infrastructure considerations for mass critical care date = 2010-03-07 keywords = ICU; capacity; care; hospital summary = RESULTS: Key recommendations include: (1) hospitals should increase their ICU beds to the maximal extent by expanding ICU capacity and expanding ICUs into other areas; (2) hospitals should have appropriate beds and monitors for these expansion areas; hospitals should develop contingency plans at the facility and government (local, state, provincial, national) levels to provide additional ventilators; (3) hospitals should develop a phased staffing plan (nursing and physician) for ICUs that provides sufficient patient care supervision during contingency and crisis situations; (4) hospitals should provide expert input to the emergency management personnel at the hospital both during planning for surge capacity as well as during response; (5) hospitals should assure that adequate infrastructure support is present to support critical care activities; (6) hospitals should prioritize locations for expansion by expanding existing ICUs, using postanesthesia care units and emergency departments to capacity, then step-down units, large procedure suites, telemetry units and finally hospital wards. doi = 10.1007/s00134-010-1761-4 id = cord-336161-67pumvst author = Himmelstein, David U. title = The U.S. Health Care System on the Eve of the Covid-19 Epidemic: A Summary of Recent Evidence on Its Impaired Performance date = 2020-06-30 keywords = Health; Medicare; hospital summary = Before the recession caused by the pandemic, tens of millions of Americans were unable to afford care, compromising their physical and financial health; deep-pocketed corporate interests were increasingly dominating the hospital industry and taking over physicians'' practices; and insurers'' profits hit record levels. 14 A new study finds that Veterans Health Administration (VA) patients, relative to Americans with non-VA coverage, are only about half as likely to skip a prescribed medication because of costs (6.1% vs 10.9% of others), despite VA patients having lower average incomes. A recent study indicates why the US advocacy organization Physicians for a National Health Program calls for Improved Medicare for All. Among seriously ill Medicare enrollees (i.e., those who have visited 3 or more physicians and been hospitalized at least twice in the past year), 53% had a serious problem paying a medical bill, 36% had used up all or most of their savings, 27% had been contacted by a collection agency, and 23% were unable to pay for basic necessities. doi = 10.1177/0020731420937631 id = cord-310117-19qsszns author = Huang, Yao title = Clinical characteristics of 17 patients with COVID-19 and systemic autoimmune diseases: a retrospective study date = 2020-06-16 keywords = COVID-19; Hospital; Tongji; patient summary = 2 7-9 We retrieved 2804 inpatients who were diagnosed with COVID-19 in two campuses of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (hereinafter referred to as Wuhan Tongji Hospital) and reported the epidemiological and clinical data of 17 inpatients suffering from systemic autoimmune diseases (AIDs), providing more information on this population and relevant therapies. We reviewed 2804 electronic clinical records at two campuses of Wuhan Tongji Hospital and extracted demographic characteristics, epidemiological history, comorbidities, clinical symptoms or signs on admission, chest CT findings, laboratory results on admission, therapies that were prescribed for COVID-19 as well as AIDs, and clinical outcomes for all 17 inpatients with systemic AIDs. All radiological assessments and laboratory testing were performed for the clinical care needs of the patients. This is a descriptive study on the epidemiology and clinical characteristics of 17 patients with COVID-19 and systemic AIDs, and an extended report on the epidemiology of 1255 inpatients with COVID-19 in Wuhan Tongji Hospital. doi = 10.1136/annrheumdis-2020-217425 id = cord-345235-wwnqupo0 author = Ji, Jianlin title = Consultation-liaison psychiatry in China date = 2012-06-17 keywords = CLP; China; hospital summary = The research component includes study of the assessment and management of the psychological and behavioral problems that occur in persons with physical illnesses, co-morbid medical and psychiatric disorders seen in general medical settings, and the evaluation of CLP clinical services and education. The survey found that almost all CLP work was focused on providing diagnoses and treatment for difficult patients on general medical services; there was no genuine consultation between psychiatrists, non-psychiatric clinicians and patients, and there was no research about developing an appropriate China-specific model of CLP. The limited CLP services available at the hospitals with departments of psychiatry are single case-based consultations; there are no full-time CLP psychiatrists who regularly participate in routine clinical care in non-psychiatric departments. Clinical study of 378 in-patients in a general hospital seen by the consultation-liaison psychiatry service doi = 10.3969/j.issn.1002-0829.2012.03.001 id = cord-017525-hvd7jv44 author = Jimenez, E. J. title = Emergency Mass Critical Care date = 2009-11-19 keywords = care; critical; hospital; plan summary = Development of a response plan is requisite for any hospital to have a significant expectation to be able to respond in a meaningful way to a sudden disaster that leaves large amounts of the population seeking emergency medical care. Within this chapter we will focus our attention on the most important considerations for managing patient care within the hospital with an emphasis on critical care in response to a mass casualty incident (MCI), as we plan to expect the unexpected. Disaster preparedness medicine focuses on preparation, response, surge, administration of resources, and recovery from events that generate demands that overwhelm the local medical community''s capacity to deliver care. The following is a summary of recommendations for preparing a Disaster Preparedness plan and delivery of EMCC, based on the most recent publications from the American College of Chest Physicians Task Force [2] and the Fundamentals of Disaster Management (FDM) [20] course of the Society of Critical Care Medicine, with emphasis in the Staff, Stuff, and Space orientation: Staff 1. doi = 10.1007/978-88-470-1436-7_30 id = cord-002510-h1eqnzn3 author = Kao, Hui-Yun title = Taiwan''s Experience in Hospital Preparedness and Response for Emerging Infectious Diseases date = 2017-04-01 keywords = Ebola; Taiwan; hospital summary = The main organizing principles of the CDCMN are centralized isolation of patients with severe highly infectious diseases and centralization of medical resources, as well as a network of designated regional hospitals like those in other countries. Following the anthrax attacks in the United States in 2001, the SARS outbreak in 2003, and 2 decades of medical system reforms, a number of countries have adopted an approach that designates specific responding hospitals at the national, regional, and/or local levels to centralize resources, build capacity, and train special medical staff. In addition, considering the continuously improving healthcare system in Taiwan, all the responding hospitals were able to take in patients with highly infectious diseases and rapidly activate the emergency response plan, regardless of the category level. Activation Procedure of a Regional Responding Hospital TAIWAN''S HOSPITAL PREPAREDNESS AND RESPONSE report back to the CECC on the results of inspections of negative pressure isolation wards, manpower mobilization, training and drill plans, PPE stockpile status, and transport procedures. doi = 10.1089/hs.2016.0105 id = cord-029612-cts1al9z author = Kaplan, Alan title = COVID-19 and Healthcare''s Productivity Shock date = 2020-06-15 keywords = hospital; patient; revenue summary = And yet, as patients shy away from hospitals and clinics, the crisis is challenging longstanding pillars of providers'' revenue models, many of which focus on in-person visit volume, high-priced procedures, and profitable markups on drugs that physicians buy and bill to insurers and patients. Revenue growth, fee for service and healthcare''s operating model This hiring pattern tracks the basic financial incentives that shape American healthcare: provider revenue growth stems from rising prices and increased service volume.3 Face-to-face visits, procedures and drug infusion all require more patient-facing staff, which creates a clear business case to add these workers. Hospitals and " practices that shift revenue away from pure fee-for-service pricing, while embracing virtual care delivery and eliminating unnecessary operational overhead could exit the crisis with more resilient businesses, while boosting the financial health of the system as a whole. doi = 10.1056/cat.20.0199 id = cord-346308-9h2fk9qt author = Kaur, Rajwinder title = Microbiology of hospital wastewater date = 2020-05-01 keywords = HWW; PCR; WWTP; antibiotic; dna; gene; hospital; human; resistance; wastewater summary = The study of hospital wastewater (HWW) microbiology is important to understand the pollution load, growth of particular pathogenic microbes, shift and drift in microbial community, development and spread of antibiotic resistance in microbes, and subsequent change in treatment efficiencies. Within past years, pieces of evidence have shown mobilization of these resistance genes from the environment into pathogenic bacteria causing health risks to humans and animals and also, demonstrating a link between environmental and clinical resistance [123] . The HWW has been reported to have two overexpressed β-lactam-resistance genes (bla GES and bla OXA ) as compared with the water collected from other aquatic bodies, which could be correlated with antibiotic usage over the time in hospitals and discharge of the residues of antibiotics in the wastewater [176] . Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: a review doi = 10.1016/b978-0-12-819722-6.00004-3 id = cord-328522-ef4xg3q0 author = Kelen, Gabor D title = Inpatient disposition classification for the creation of hospital surge capacity: a multiphase study date = 2006-11-30 keywords = event; hospital; medical; risk summary = The aim of this phase was to develop a disposition classifi cation system (reverse triage) based on risk tolerance of a consequential medical event as a result of discharge; assuming that critical interventions were withdrawn or withheld. We focus on the main components of the fi rst phase: (1) conceptualisation of the disposition classifi cation system; (2) development of operational defi nitions of consequential medical events and critical interventions; and (3) derivation of risk estimates related to early discharge from a multidisciplinary panel of experts. After the defi nitions had been decided on, the panellists voted to defi ne the upper limit of acceptable risk for the occurrence of a consequential medical event (ie, need for critical intervention), for each of the categories of the disposition classifi cation system. doi = 10.1016/s0140-6736(06)69808-5 id = cord-018335-4l7scdqk author = Kiechle, Frederick L. title = Utilization Management in a Large Community Hospital date = 2016-12-01 keywords = Gram; MALDI; TOF; clinical; culture; hospital; laboratory; test summary = In preparation for the shift from fee-for-service to a valuebased payment system [ 15 ] large community hospitals have been actively engaged in three enterprises which will impact laboratory test utilization: buying physician practices, increasing the use of hospitalists and consolidation of hospitals. Certainly, utilization management of POCT programs will require investigations to determine the relationship between total laboratory turn-around time for results, patient outcome and hospital costs using cost effectiveness analyses [ 36 ] . As technology advances, the traditionally " agrarian society " of the laboratory is becoming more industrialized with the implementation of automation, molecular based testing, and use of mass spectrometry ( MALDI-TOF -Matrix-Assisted Laser Desorption Ionization-Time of Flight). However, all of these technological advances are shortening the time for a laboratory diagnosis and ultimately maximizing the impact to patient care and how physicians at a large community hospital will utilize the more rapid microbiology laboratory services. doi = 10.1007/978-3-319-34199-6_14 id = cord-323449-r1gyjxei author = Kim, Uh Jin title = Air and Environmental Contamination Caused by COVID-19 Patients: a Multi-Center Study date = 2020-09-08 keywords = Hospital; SARS summary = BACKGROUND: The purpose of this study was to determine the extent of air and surface contamination of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in four health care facilities with hospitalized coronavirus disease 2019 (COVID-19) patients. CONCLUSION: Our data suggest that remote (> 2 m) airborne transmission of SARS-CoV-2 from hospitalized COVID-19 patients is uncommon when aerosol-generating procedures have not been performed. 10, 11 The objectives of the present study were 1) to investigate air and environmental contamination caused by COVID-19 patients in a variety of hospital settings; 2) to evaluate the effectiveness of environmental cleaning; and 3) to examine the potential for remote airborne transmission in the absence of aerosol-generating procedures. Despite extensive surface sampling, SARS-CoV-2 RNA was not detected in the room in Hospital B (AIIR with routine surface cleansing using disinfectant wipes the patient''s respiratory samples (Ct value 22.4-28.9) (Fig. 1B) . doi = 10.3346/jkms.2020.35.e332 id = cord-000011-seass3p0 author = Li, Xingming title = An analysis of hospital preparedness capacity for public health emergency in four regions of China: Beijing, Shandong, Guangxi, and Hainan date = 2008-09-20 keywords = China; PHE; hospital summary = For the purpose of this study, we analyzed the data focused on the following nine areas of interest: (1) hospi-tal''s demographic data (including region, SARS crisis experience, teaching function, hospital type, and number of medical staff in related departments); (2) hospital PHE preparation (emergency plans, response initiating time, accessibility, and revision and implementation of emergency plan); (3) response to a community PHE (cooperation with local organizations, relationship with the community PHE network, medical treatment, and rescue work in the community); (4) stockpiles of drugs and materials (stockpiles of drugs and other resources and personal protective equipment); (5)PHE detection and identification (syndrome surveillance); (6) procedures for medical treatment (protocol for diagnosis, treatment, and transfer of PHE victims); (7) laboratory diagnosis and management (laboratory regulation and management system, sample disposal and evaluation system, collection and disposal of suspected samples, and diagnosis of pathogen/etiology); (8) staff training (organization of PHE training, current training of medical staff, curriculum development and training effectiveness assessment); and (9) risk communication (organization for communication of risk psychological counseling to victim and medical staff, and communication with public). doi = 10.1186/1471-2458-8-319 id = cord-323421-67r1qmc9 author = Liao, Yunfei title = Clinical Characteristics and Risk factors for developed COVID-19 patients transferring to designated hospital from Jianghan Fangcang shelter Hospital: a retrospective, observational study date = 2020-04-24 keywords = COVID-19; Fangcang; hospital summary = title: Clinical Characteristics and Risk factors for developed COVID-19 patients transferring to designated hospital from Jianghan Fangcang shelter Hospital: a retrospective, observational study Methods This study enrolled all cases (no=1848) with mild or moderate type of COVID-19 in Fangcang shelter hospital of Jianghan in Wuhan from Feb 5th to Mar 9th, 2020. The patients from mild or moderate type to severe type showed the following clinical characteristics: the median incubation (onset to shelter) period was 10 days; they were all symptomatic at admission; fever, cough, and fatigue were the most common symptoms; hypertension, diabetes and coronary heart diseases were common co-morbidities; most of the patients had elevated levels of CRP at ill onset with 33.3% over 10 mg per L; bilateral distribution and ground-glass opacity were the most common manifestations in chest CT. 21.20074724 doi: medRxiv preprint retrospective cohort study to disclose the clinical characteristics and risk factors for developed COVID-19 patients transferring to the designated hospital in Fangcang shelter hospital. doi = 10.1101/2020.04.21.20074724 id = cord-318367-8xrjddwy author = Liu, Xiucheng title = An especial transition phase of hospitals: the adaptation of hospital operations to the development of COVID-19 and policy adjustments date = 2020-09-21 keywords = COVID-19; hospital summary = Therefore, gradually promoting hospital operations and functions back to the new normal is important, especially when this outbreak has been effectively controlled. Normalizing hospital operations too early may increase the risk of exposure and cross-contamination, which may have a catastrophic effect on both the elderly patients and medical staff. Indeed, the fear of being infected in hospitals, "stay at home" policies, and emergency measures taken by hospitals, such as delaying elective operations and non-urgent radiological scans, have inevitably caused adverse consequences on the treatment modalities and day-to-day care of patients with chronic underlying conditions. For instance, after the epidemic was well controlled, some patients scheduled for surgery, including those with lung cancer and valvular heart diseases, voluntarily rescheduled their procedure at The Affiliated Hospital of Xuzhou Medical University. During the COVID-19 outbreak, medical staff, especially those in the front-line of the epidemic, have endured enormous work-load and psychological pressure [6, 7] . doi = 10.1186/s12199-020-00891-4 id = cord-293126-6ae1p15w author = Liu, Yu title = Establishing Appropriate Agency Relationships for Providers in China date = 2019-08-27 keywords = China; chinese; hospital; physician summary = This commentary proposes 2 essential steps to establish such physician-hospital agency relations: (1) minimize financial ties between senior physicians and tertiary-level public hospitals by establishing a separate reimbursement system for senior physicians, and (2) establishing a comprehensive physician professionalism system underwritten by the Chinese government, professional physician associations, and major health care facilities as well as by physician leadership representatives. 11, 12, 16 More recently, the existing strong financial relation between senior physicians and tertiary public hospitals also has jeopardized efforts to create competition from emerging private hospitals as well as reform measures that allow physicians to practice among multiple health care facilities. We recognize the significant investment of time and funding necessary to implement an independent physician reimbursement system for senior physicians at tertiary public hospital level; however, given the current situation in China, the advantages of such a major reform outweigh the disadvantages, especially considering the expected long-term effects on efficiency and quality of service within the health care delivery system. doi = 10.1177/0046958019872348 id = cord-026347-rqlrt3ke author = Lloyd-Smith, McKenzie title = The COVID-19 pandemic: resilient organisational response to a low-chance, high-impact event date = 2020-05-18 keywords = Christchurch; Hospital; improvisation summary = The global healthcare sector is currently in the midst of the COVID-19 pandemic, a ''low-chance, high-impact'' event which will require healthcare systems, and the organisations within them, to maintain organisational resilience in order to respond effectively. By drawing on the case of Christchurch Hospital''s response to a major earthquake, this paper demonstrates the vital role that improvisation can play within a clinical setting, when responding to a low-chance, high-impact event. 2 This ability to creatively respond within uncertain conditions makes improvisation during a low-chance, high-impact event not only possible, but critically important for a resilient organisational response. 22 By creating a shared understanding of the unfolding situation and facilitating communication throughout the response, Christchurch Hospital''s leadership enabled frontline staff to coordinate under novel circumstances, 21 allowing individuals to improvise solutions to problems and understand how their actions and decisions were embedded within a larger operation. doi = 10.1136/leader-2020-000245 id = cord-334867-ohw0chbg author = Ma, Hui title = Hospital biosecurity capacitation: Analysis and recommendations from the prevention and control of COVID-19 date = 2020-05-27 keywords = COVID-19; hospital; treatment summary = Accordingly, the study put forward the following countermeasures and suggestions for hospitals to deal with future biosecurity events, such as a major epidemic: first, there is a need to build biosecurity management systems and emergency response mechanisms in hospitals; second, the investment and guarantee mechanisms for hospital biosecurity construction should be improved; third, the capacity building of biosecurity incident treatment needs attention in general hospitals; and fourth, comprehensive plans need to be developed for the integrated construction of medical treatment and prevention facilities through disease-control systems. With the large number of patients visiting hospitals, the poor information exchange among medical institutions, disease control institutions, and scientific research institutions caused doctors to have scant knowledge of the epidemiological characteristics, transmission patterns, and human-to-human transmission of SARS-CoV-2 infection, with the consequence of disappointing treatment results [9] . doi = 10.1016/j.jobb.2020.05.001 id = cord-291168-4u4cssky author = Martin-Villares, Cristina title = Outcome of 1890 tracheostomies for critical COVID-19 patients: a national cohort study in Spain date = 2020-08-04 keywords = COVID-19; Hospital; patient summary = METHODS: A multicentric prospective observational study of 1890 COVID-19 patients undergoing tracheostomy across 120 hospitals was conducted over 7 weeks in Spain (March 28 to May 15, 2020). The group has performed a national multicentric prospective observational study on 1890 COVID-19 critical patients undergoing tracheostomy in a total of 120 hospitals in Spain. On early March, 2020, at a very critical moment of the pandemic in Spain and without published data yet from initial experiences in China or Italy, Spanish otolaryngologists began their first tracheostomies in Madrid (March, 11) and Barcelona (March, 16) , with the onrush of more than a thousand patients in their respective overcrowded ICUs, which doubled its current capacity. Between March 28 and May 15, the Spanish COVID Group, encompassing 120 hospitals, performed 1890 tracheostomies, the equivalent of 16.4% of all registered ICU patients with mechanical ventilation in Spain. doi = 10.1007/s00405-020-06220-3 id = cord-007049-02p8ug67 author = McGeer, Allison title = Let Him Who Desires Peace Prepare for War: United States Hospitals and Severe Acute Respiratory Syndrome Preparedness date = 2004-07-15 keywords = SARS; hospital summary = In June 2003, the Centers for Disease Control and Prevention (CDC) surveyed members of the Infectious Disease Society of America Emerging Infections Network (EIN) about SARS preparedness in their hospitals. Of the 456 EIN members responding to the survey in this issue of Clinical Infectious Diseases [2] , 381 (83%) reported that patients with respiratory symptoms in their emergency department (ED) would be screened for a travel history. A careful assessment of exposures in SARS outbreaks, particularly those due to superspreading events and transmission despite compliance with isolation precautions, is needed to determine whether airborne spread occurs [10, [13] [14] [15] . At least 2 analyses of risks associated with health care worker infection despite the use of precautions now identify that 12 h of infection-control training and confidence that precautions would be protective are associated with substantial reductions in the risk of infection (Toronto SARS hospital investigation, unpublished data; Lau et al. Hospital preparedness for severe acute respiratory syndrome in the United States: views from a national survey of infectious diseases consultants doi = 10.1086/421784 id = cord-255269-rx68247n author = Medeiros, Eduardo Alexandrino Servolo title = CHALLENGES IN THE FIGHT AGAINST THE COVID-19 PANDEMIC IN UNIVERSITY HOSPITALS date = 2020-04-22 keywords = hospital summary = key: cord-255269-rx68247n authors: Medeiros, Eduardo Alexandrino Servolo title: CHALLENGES IN THE FIGHT AGAINST THE COVID-19 PANDEMIC IN UNIVERSITY HOSPITALS cord_uid: rx68247n Research support is essential in the search for effective medications -in the clinical protocol phase at the moment -and a vaccine, which will probably be available only in 2021, after this pandemic is over. As health professionals, we must prepare for the worse in the coming weeks, protect ourselves, have hope, and be on the front line, contributing to this critical and historic fight against this novel coronavirus. A novel coronavirus from patients with pneumonia in China A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China The authors declare no conflict of interests. doi = 10.1590/1984-0462/2020/38/2020086 id = cord-017281-b1kubfl0 author = Milcent, Carine title = Hospital Institutional Context and Funding date = 2018-02-15 keywords = China; Health; Reform; hospital; private summary = The "non-profit" category mainly consists of organizations owned by government and companies (available data do not permit a disaggregation of the non-profit category by ownership) This fragmented structure is a hurdle to the implementation of any hospital reform, with four main ministries involved: the National Development and Reform Commission (NDRC), the Ministry of Human Resources and Social Security (MoHRSS), the Ministry of Finance (MoF) and obviously the Ministry of Health (MoH). To mitigate this risk, each authority in charge of implementation at the local level is given measurable targets, for instance, the number of people covered by public health insurance at a certain date. Another part of the reform aimed at developing private hospitals is their inclusion into public health insurance schemes. Rules tend to vary depending on the area, but there is an increasing number of cases for which care provided in private healthcare centres can be covered by public insurance schemes. doi = 10.1007/978-3-319-69736-9_4 id = cord-348629-fnn9wshy author = Moccia, Giuseppina title = An alternative approach for the decontamination of hospital settings date = 2020-10-21 keywords = cleaning; disinfectant; hospital; surface summary = AIM: This work aims to report the development, implementation, and validation of cleansing and sanitizing procedure for critical clinical settings through the innovative use of disposable cloths pre-impregnated with solutions containing different active formulations and biocidal agents, relating to the areas to be treated (low, moderate, high-risk). Cleaning (products and procedures) and environmental disinfection; use of work equipment; correct use of the trolley, that is specifically designed to contain separately pre-impregnated cloths for the different surfaces and allows to avoid contact between dirty and clean cloths; definition of internal paths (clean/dirty); personal hygiene; hand washing; adoption of measures to prevent the transmission of infections; use of the supplied devices; staff clothing; disposal of medical waste; risk management; quality plan; significant impact. The use of a disinfectant solution pre-impregnated microfiber or spunlace cloth for different kinds of surfaces was supported by an appropriated trolley designed to help the operator during the cleaning procedure. doi = 10.1016/j.jiph.2020.09.020 id = cord-005808-w0763esk author = Moreno, Gerard title = Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study date = 2018-08-03 keywords = Hospital; ICU; corticosteroid; patient summary = CONCLUSION: Administration of corticosteroids in patients with severe influenza pneumonia is associated with increased ICU mortality, and these agents should not be used as co-adjuvant therapy. Therefore, the aim of the present study was to identify the factors associated with corticosteroid use and its impact on intensive care unit (ICU) mortality using propensity score (PS) matching analysis in ICU patients with influenza pneumonia. Our results strongly suggest that administration of corticosteroids as co-adjuvant therapy to standard antiviral treatment in critically ill patients with severe influenza pneumonia is associated with increased ICU mortality. Three recent systematic reviews and meta-analyses [41] [42] [43] concluded that corticosteroid therapy is significantly associated with mortality, even in the subgroup of patients with influenza hospitalized in or outside the ICU. In a homogeneous group of critically ill patients with severe influenza pneumonia, after adequate adjustment by PS matching and competing risks, co-adjuvant corticosteroid therapy was significantly associated with increased ICU mortality. doi = 10.1007/s00134-018-5332-4 id = cord-340091-kptilmi8 author = Mulatu, H. A. title = The prevalence of common mental disorders among health care professionals during the COVID-19 pandemic at a tertiary Hospital in East Africa date = 2020-11-03 keywords = COVID-19; Hospital; Paul summary = A recent study among 1257 healthcare professionals in a tertiary hospital in China, revealed a high prevalence of mental health symptoms among HCWs. Overall, 50.4%, 44.6%, 34.0%, and 71.5% of health workers reported symptoms of depression, anxiety, insomnia, and distress, respectively. The aims of the current study were to determine the prevalence of depression, anxiety, insomnia, and psychological distress among HCWs and associated factors during the COVID-19 pandemic at St. Paul''s Tertiary Hospital, Addis Ababa, Ethiopia. The study was a cross-sectional, hospital-based survey that was conducted to assess the prevalence of depression, anxiety, insomnia, and mental distress among healthcare workers at St. Paul''s Hospital during the COVID-19 pandemic from August 1 st , 2020 up to August 30, 2020. doi = 10.1101/2020.10.29.20222430 id = cord-253161-oz1eziy1 author = Munyikwa, Michelle title = MY COVID‐19 DIARY date = 2020-06-04 keywords = Philadelphia; States; United; hospital; pandemic summary = Written in weekly instalments, Michelle Munyikwa''s Covid‐19 diary reflects upon the experience of an unfolding pandemic from her dual role as a medical trainee and anthropologist living in the United States. In this narrative, Michelle Munyikwa, an anthropologist and medical doctor-in-training, reflects on developments in the Covid-19 pandemic in the form of a diary from Philadelphia. Scrolling social media feeds, one is inundated by reports from other countries, graphs and tables attempting to predict the future, and calls to understand the past of previous epidemics such that we might not repeat our errors. This uniquely 21st-century crisis is an object lesson in what it feels like to live through an emerging epidemic during what has often been described as an age of anxiety. We will need to worry about the chronically ill and the fact that many American hospitals cannot handle a surge in patients at this time of year. doi = 10.1111/1467-8322.12575 id = cord-326991-m0lfk0a9 author = Nuñez, Jorge H. title = Rethinking Trauma Hospital Services in one of Spain''s Largest University Hospitals during the COVID-19 pandemic. How can we organize and help? Our experience. date = 2020-09-25 keywords = covid-19; hospital; patient summary = Each decision requires an individualized risk/benefit assessment, with the aims of protecting healthcare personal and patients, helping hospitals deal with Covid-19 lines, and not compromising the assessment and outcomes of our patients. Personnel have been organized to support the Covid-19 units, to cover trauma care (emergency clinical visits and emergent surgeries), operating rooms (delayed fracture emergencies) and clinical consultations (general and specialized consultations via telemedicine). We reduced to a third our orthopaedics and trauma hospital beds, provided coverage for general emergency services and five ICUs, all the while continuing to provide care for our patients, in the form of 102 trauma surgeries, 6413 phone interviews and 520 emergency clinic visits. We reduced to a third our orthopaedics and trauma hospital beds, provided coverage for general emergency services and five ICUs, all the while continuing to provide care for our patients, in the form of 102 trauma surgeries, 6413 phone interviews and 520 emergency clinic visits. doi = 10.1016/j.injury.2020.09.055 id = cord-268462-w8trclz6 author = Oh, Eunja title = Factors influencing the adherence of nurses to standard precautions in South Korea hospital settings date = 2019-11-30 keywords = adherence; hospital summary = Results A higher, or positive, attitude was the strongest influencing factor in adherence to SPs in the final model, followed by administrative support, hospital types, and safety climate, in descending order. 10, 13 This study aimed to understand how sociodemographic and individual factors, such as knowledge and attitude, along with institutional factors such as safety climate and administrative support, influence the adherence of nurses to SPs in South Korean hospitals following the 2015 MERS outbreak. To identify the respective effects of knowledge, attitude, safety climate, and administrative support of nurses on adherence to SP, this study conducted a hierarchical linear regression, controlling for confounding variables that were found to have significant difference and correlation. Based on the study of Haile et al, 10 analysis of sociodemographic factors as level 1 (age, hospital types, and length of clinical experience), individual factor as level 2 (attitude), and institutional factors as level 3 (safety climate and administrative support) was performed in descending order. doi = 10.1016/j.ajic.2019.05.015 id = cord-305207-fgvbrg8d author = Ohara, Hiroshi title = Fact-finding Survey of Nosocomial Infection Control in Hospitals in Kathmandu, Nepal—A Basis for Improvement date = 2013-06-29 keywords = control; hospital; infection summary = In the healthcare setting, particularly in developed countries, various measures including the organization of infection control teams (ICTs), preparation of manuals, strengthening of surveillance systems, and training of staff have been taken to assure effective control. The form consisted of the following items: "general information of the hospitals, control system including manual and infection control committees (ICC), equipment and facility preparedness, training conditions, surveillance conditions, expectation for international cooperation and current problems. Among the problems observed in the study were weak ICC function, few training opportunities among the hospital staff, inadequate use of antibiotics, shortage of infection control staff, shortage of doctors and nurses and their overload in daily medical practice, shortage of fundamental equipment including PPE, inadequate practice of basic techComparison of nosocomial infection control conditions between 2003 and 2011 at five national hospitals showed an improvement trend. Appropriate nosocomial infection control is a key strategy in providing high quality medical care, and effective measures are particularly required in developing countries, where the frequency of infectious diseases is high and environmental conditions of hospitals are poor [14, 15] . doi = 10.2149/tmh.2013-03 id = cord-018483-aj8yknky author = Ortiz Posadas, Martha R. title = Medical Technology Management in Hospital Certification in Mexico date = 2010-05-28 keywords = hospital; iso; quality summary = That is why many hospitals in Mexico, both public and private, have incorporated into their organization a Biomedical Engineering Department (BED) with the purpose of integrating all engineering and management processes for assurance of the optimal use of all technological supplies in the hospital, helping in the quality of health services provided to patients. The purpose of this study is to show how the medical technology management done by the BED at the hospitals contributes both to health services quality and as an element required for certification. That is why the objective of this study was to develop a quality plan (based on NMX-CC-9001-IMNC-2000) containing the process related to this activity, in order to support the implementation of a QMS and the certification of three specific health services at the hospital, namely pathology, clinical laboratory, and blood bank. doi = 10.1007/978-0-387-49009-0_5 id = cord-274239-xuwoqy18 author = Ortiz-Barrios, Miguel title = Evaluation of hospital disaster preparedness by a multi-criteria decision making approach: The case of Turkish hospitals date = 2020-07-05 keywords = FAHP; NIS; TOPSIS; disaster; hospital summary = This model was developed using fuzzy analytic hierarchy process (FAHP)-fuzzy decision making trial and evaluation laboratory (FDEMATEL)-technique for order preference by similarity to ideal solutions (TOPSIS) techniques and aimed to determine a ranking for hospital disaster preparedness. FAHP is used to determine weights of six main criteria (including hospital buildings, equipment, communication, transportation, personnel, flexibility) and a total of thirty-six sub-criteria regarding disaster preparedness. In this study, a hybrid fuzzy decision making model was proposed to evaluate the disaster preparedness of Turkish hospitals. To tackle this disadvantage, an Excel-based decision support system has been properly designed and adopted to accelerate the disaster preparedness evaluation in relation to: i) weighting and prioritizing disaster readiness criteria and sub-criteria, ii) identifying the dispatchers and receivers within the disaster management scenario, iii) ranking the hospitals according to their preparedness level, and iv) defining focused operational strategies for increasing the response of hospitals against outbreaks. doi = 10.1016/j.ijdrr.2020.101748 id = cord-004946-3tlp38yr author = Perkins, G.D. title = Basismaßnahmen zur Wiederbelebung Erwachsener und Verwendung automatisierter externer Defibrillatoren: Kapitel 2 der Leitlinien zur Reanimation 2015 des European Resuscitation Council date = 2017-06-29 keywords = AED; Beatmung; CPR; Patienten; Wiederbelebung; arrest; cardiac; hospital; und summary = Bei der Herzdruckmassage soll eine adäquate Drucktiefe sicher erreicht werden (etwa 5 cm, jedoch nicht mehr als 6 cm beim normalen Erwachsenen), bei einer Kompressionsfrequenz von 100-120/min mit minimalen Unterbrechungen. Reanimation ohne Beatmung ("compression-only CPR") Tierversuche zeigten, dass eine Wiederbelebung nur durch Thoraxkompression in den ersten wenigen Minuten nach einem nicht asphyktischen Kreislaufstillstand genauso effektiv sein kann wie eine Kombination aus Herzdruckmassagen und Beatmungen [140, 166] . The influence of scenario-based training and real-time audiovisual feedback on out-ofhospital cardiopulmonary resuscitation quality and survival from out-of-hospital cardiac arrest The System-Wide Effect of Real-Time Audiovisual Feedback and Postevent Debriefing for In-Hospital Cardiac Arrest: the Cardiopulmonary Resuscitation Quality Improvement Initiative Conventional and chest-compression-only cardiopulmonary resuscitation by bystanders for children who have out-of-hospital cardiac arrests: a prospective, nationwide, population-based cohort study Defibrillation or cardiopulmonary resuscitation first for patients with out-of-hospital cardiac arrests found by paramedics to be in ventricular fibrillation? doi = 10.1007/s10049-017-0328-0 id = cord-005041-1d95mz2f author = Perkins, G.D. title = Basismaßnahmen zur Wiederbelebung Erwachsener und Verwendung automatisierter externer Defibrillatoren: Kapitel 2 der Leitlinien zur Reanimation 2015 des European Resuscitation Council date = 2015-11-09 keywords = AED; CPR; Wiederbelebung; cardiac; hospital; und summary = 2005 wurde dieses Konzept infrage gestellt, da Evidenz dafür vorlag, dass Thoraxkompressionen von bis zu 180 s vor einer Defibrillation das Überleben verbessern können, wenn der Rettungsdienst erst nach mehr als 4−5 min eintrifft [196, 197] . Der ERC empfiehlt, dass CPR fortgeführt werden soll, während ein Defibrillator oder AED gebracht und angelegt wird, aber dann soll die Defibrillation nicht weiter verzögert werden. Conventional and chest-compression-only cardiopulmonary resuscitation by bystanders for children who have out-of-hospital cardiac arrests: a prospective, nationwide, populationbased cohort study Impact of dispatcher-assisted bystander cardiopulmonary resuscitation on neurological outcomes in children with out-of-hospital cardiac arrests: a prospective, nationwide, population-based cohort study Public access defibrillation improved the outcome after out-of-hospital cardiac arrest in schoolage children: a nationwide, population-based, Utstein registry study in Japan Defibrillation or cardiopulmonary resuscitation first for patients with out-of-hospital cardiac arrests found by paramedics to be in ventricular fibrillation? doi = 10.1007/s10049-015-0081-1 id = cord-291272-srt08jh8 author = Peters, E.J.G. title = Outcomes of persons with COVID-19 in hospitals with and without standard treatment with (Hydroxy)chloroquine date = 2020-10-14 keywords = H)CQ; hospital summary = When stratified by actually received treatment in individual subjects, the use of (hydroxy)chloroquine was associated with an increased 21-day mortality (HR 1.58; 95%CI 1.24-2.02) in the full model. CONCLUSIONS: After adjustment for confounders, mortality was not significantly different in hospitals that routinely treated patients with (hydroxy)chloroquine, compared with hospitals that did not. The objective of this 142 study was to compare the effect of hospital-wide COVID-19 treatment strategies with or without 143 routine (H)CQ use on all-cause 21-day mortality. We performed a survival analysis using 177 log-rank test and Cox-regression with adjustment for age, sex, time in the pandemic (i.e., the number 178 of elapsed days after March 1 st 2020 at hospital admission),and covariates based on premorbid 179 health (i.e., history of lung, kidney and cardiovascular disease, diabetes mellitus, obesity, and 180 neoplasms or hematologic disease), disease severity during presentation (respiratory rate, oxygen 181 saturation) and the use of steroids, including dexamethasone, for adult respiratory distress 182 syndrome (ARDS) 12,13 . doi = 10.1016/j.cmi.2020.10.004 id = cord-259510-6atk2pt0 author = Puro, Neeraj A. title = Telehealth Availability in US Hospitals in the Face of the COVID‐19 Pandemic date = 2020-06-30 keywords = hospital summary = METHODS: Based on 2017 data from the American Hospital Association survey, Area Health Resource Files and Medicare cost reports, we used logistic regression models to identify predictors of telehealth and eICU capabilities in US hospitals. Hospitals'' odds of possessing the capability to provide such services vary largely by region; overall, rural hospitals have more widespread telehealth capabilities than urban hospitals. This study utilized a cross-sectional analysis of acute care hospitals in the United States to examine the association between various organizational and environmental factors, and rural hospitals'' possession of telehealth and eICU capabilities. Hospitals in rural areas were more likely to possess telehealth capabilities compared to hospitals in urban areas, although the odds ratio was only marginally significant (OR = 1.34, P < .10). We found that hospitals'' odds of possessing such capabilities vary to a large extent by region; overall, the rural health system appears to have more widespread telehealth capabilities than urban hospitals. doi = 10.1111/jrh.12482 id = cord-280184-91d8i6ix author = Querido, Micaela Machado title = Self-disinfecting surfaces and infection control date = 2019-06-01 keywords = Staphylococcus; antimicrobial; bacteria; contamination; hospital; infection; microorganism; surface summary = Surfaces with anti-adhesive properties, with incorporated antimicrobial substances or modified with biological active metals are some of the strategies recently proposed. This review intends to summarize the problems associated with contaminated surfaces and their importance on infection spreading, and to present some of the strategies developed to prevent this public health problem, namely some already being commercialized. This review considered English-language articles retrieved from PubMed database literature searches, bibliographies from published articles, and infection-control books and chapters, in a total of 205 references published between 2000 and 2018, considering the following criteria: the most recent studies performed on microbiological analysis on different surfaces reporting samplings performed on food contact surfaces, public spaces and hospital surfaces, where microorganisms occur naturally. All those antimicrobial substances are loaded to the surface either by immobilization or by incorporation on the bulk material; recent studies on the application of each type of loading strategy are summarized next. doi = 10.1016/j.colsurfb.2019.02.009 id = cord-279709-cnd41l1d author = Rajakulasingam, R. title = Standard operating procedure of image-guided intervention during the COVID-19 pandemic: a combined tertiary musculoskeletal oncology centre experience date = 2020-07-21 keywords = Hospital; Orthopaedic; Royal summary = Materials and methods The present study was a retrospective review of all patients undergoing image-guided intervention in the computed tomography (CT) and normal ultrasound (US) rooms from 24 March 2020 to 24 May 2020 (during the COVID-19 pandemic peak) at Royal National Orthopaedic Hospital, London, and Royal Orthopaedic Hospital, Bristol, UK. Measures were put in place to address air pressures, airflow direction, aerosol generation, and the safe utilisation of existing scanning rooms and work lists for interventional procedures. Given the time needed for deep cleaning and minimising potential viral transmission, the biopsy list was curtailed to have only a maximum of four GA cases at the Royal National Orthopaedic Hospital. Again, no extraction ventilation system was present with less than required minimum number of ACH; however, unlike the Royal National Orthopaedic Hospital, there was no neighbouring room with adequate ACH and no method of maintaining a negative pressure environment. doi = 10.1016/j.crad.2020.07.008 id = cord-285226-4ydvjmr3 author = Sekhar, Laligam N. title = The Future of Skull Base Surgery: A View Through Tinted Glasses date = 2020-06-27 keywords = base; hospital; patient summary = This leads to an examination of recent developments in the field and outlines several promising areas of future improvement in skull base surgery, per se, as well as identifying new hospital support systems needed to accommodate these changes. These include, but are not limited to advances in imaging, Raman Spectroscopy and Microscopy, 3-dimensional printing and rapid prototyping, master-slave and semi-autonomous robots, artificial intelligence applications in all areas of medicine, tele-medicine, and green technologies in hospitals. 44 45 More recent technological introductions have proceeded to revolutionize the 46 treatment of challenging skull base pathology including the introduction of 47 endoscopic surgery, advances in neuroimaging, radiosurgery and high energy 48 focused radiotherapy, the perfection of vascular bypasses for replacement of 49 major arteries and venous sinuses involved by tumors 1,2,3 , and the use of skull 50 base approaches to treat complex vascular lesions. Humanoid robotic nursing assistants 558 will be developed and widely used in future due to health care worker shortages, 559 patients'' desire to have 24x7 nursing assistance, and the needs created by 560 infectious diseases wherein human-human contact must be minimized. doi = 10.1016/j.wneu.2020.06.172 id = cord-254666-18gfs5sl author = Sezgin, Duygu title = The effectiveness of intermediate care including transitional care interventions on function, healthcare utilisation and costs: a scoping review date = 2020-08-04 keywords = care; hospital; intervention; transitional summary = Therefore, this scoping review seeks to identify and analyse a broad range of literature published in relation to the effectiveness of intermediate care including transitional care for middle-aged and older adults and to understand the benefits of these interventions, with a specific focus on health-related outcomes including function (activities of daily living), healthcare use and associated costs. (3) Aim of study; (4) Definitions provided for transitional or intermediate care; (5) Intervention details; (6) Technology usage; (7) Population characteristics (such as mean age and sample size); (8) Health condition/problem; (9) Context/setting that the recruitment took place; (10) Structure/ governance of intervention; (11) Outcomes reported (function, ED visits, hospital stay, institutionalisation, other); (12) Resource implications (such as cost and staffing); (13) Transferable lessons for policy and practice; (14) Barriers/ limitations reported; and (15) Additional recommendations/ comments. doi = 10.1007/s41999-020-00365-4 id = cord-271679-94h6rcih author = Sharififar, Simintaj title = Factors affecting hospital response in biological disasters: A qualitative study date = 2020-03-16 keywords = Health; Iran; biological; disaster; hospital; participant summary = Results: After analyzing 12 interviews, extraction resulted in 76 common codes, 28 subcategories, and 8 categories, which are as follow: detection; treatment and infection control; coordination, Resources; training and exercises; communication and information system; construction; and planning and assessment. The common codes derived from these subcategories are as follow: the ability to control infections during deliberate or natural biological outbreaks; the availability of preventive drugs at a predetermined time during an epidemic of communicable diseases; appropriate vaccination of people at risk; and the safety of hospitalized or outpatients patients in the outbreak of infectious diseases; and waste management. In this qualitative study, which was done using content analysis, the effective factors for hospital performance in biological emergencies in IR of Iran were identified as follow: diagnosis; treatment and control of infection; resources; coordination; training and practice; communication and information systems; construction; and planning and assessment. doi = 10.34171/mjiri.34.21 id = cord-303966-z6u3d2ec author = Shears, P. title = Poverty and infection in the developing world: Healthcare-related infections and infection control in the tropics date = 2007-10-22 keywords = Africa; hospital; infection summary = In many hospitals serving the poorest communities of Africa and other parts of the developing world, infection control activities are limited by poor infrastructure, overcrowding, inadequate hygiene and water supply, poorly functioning laboratory services and a shortage of trained staff. Summary In many hospitals serving the poorest communities of Africa and other parts of the developing world, infection control activities are limited by poor infrastructure, overcrowding, inadequate hygiene and water supply, poorly functioning laboratory services and a shortage of trained staff. Many medical journals are currently devoting part of their current issues to the themes of poverty and infection in the developing world, in recognition of the commitments made by the G8 Summit and the United Nations (UN) Millenium Development Goals (MDGs) to improve maternal healthcare, reduce childhood mortality and the impact of human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS), malaria and other communicable diseases. doi = 10.1016/j.jhin.2007.08.016 id = cord-329447-kjeqs6zh author = Shen, Bingzheng title = Wuchang Fangcang Shelter Hospital: Practices, Experiences, and Lessons Learned in Controlling COVID-19 date = 2020-07-04 keywords = Fangcang; Hospital; Shelter summary = A large comprehensive gymnasium was converted into Wuchang Fangcang Shelter Hospital in order to provide adequate medical beds and appropriate care for the confirmed patients with mild to moderate symptoms. Since more than 80% of COVID-19 patients were mild or moderate types [4] [5] [6] , a novel public health measure, Fangcang Shelter Hospitals, was conceived [7] . During this major public health emergency, pharmacists, as a member of the medical team, have been responsible for providing professional and superior pharmaceutical services. Relying on the 5G network and medical information systems, the team of pharmacists accomplished pharmaceutical services smoothly, helping to reduce the risk of occupational exposure in the Shelter Hospital. In the pharmaceutical services provided at Wuchang Fangcang Shelter Hospital, ACE-I and ARBs were not recommended, but now, the latest joint viewpoint from three U.S. heart groups states that patients with COVID-19 should take ACE inhibitors and ARBs [14] . doi = 10.1007/s42399-020-00382-1 id = cord-310621-wnd47uss author = Singh, Shalendra title = Challenges faced in establishing a dedicated 250 bed COVID-19 intensive care unit in a temporary structure date = 2020-11-06 keywords = ICU; hospital summary = While this availability of trained manpower and specialized equipment makes it possible to care for critically ill patients, it also presents singular challenges in the form of man and material management, design concerns, budgetary concerns, and protocolization of treatment. However, some difficulties were 7 faced since a consultant intensivist was not involved during the initial (first 3 days) of planning 8 of the architectural design of the hospital, leading to a few points being overlooked during the 9 initial planning, such as the integration of a shower area in the doffing zone, establishment of fire 10 safety protocols and evacuation plan, maintenance of optimal temperature of the ICU, and 11 provision of uninterruptible power supply (UPS) system and generator backup for the ICU, 12 especially the ventilators. doi = 10.1016/j.tacc.2020.10.006 id = cord-264952-0t0t4x0y author = Smith, Sean R title = Proposed Workflow for Rehabilitation in a Field Hospital Setting During the COVID‐19 Pandemic date = 2020-05-15 keywords = field; hospital; patient summary = [1, 5] Without rehabilitation, numerous patients may require extra days in the field hospital setting, taking up needed bed space and increasing use of PPE and healthcare personnel. Patients with more impaired function and who have clear barriers to discharge modifiable with rehabilitation intervention -including not being able to navigate steps to enter their house and requiring assistance for transfers -will be triaged to receive as much physical and occupational therapy as resources allow, with physiatry involvement as indicated to help with discharge planning and symptom management. When a field hospital has no dedicated space for rehabilitation, patients should receive appropriate ongoing therapies and be provided with information regarding bed exercises, exercises with family, and home exercise programs that appropriately address the symptoms of the disease. doi = 10.1002/pmrj.12405 id = cord-011269-j2rogzm7 author = Stefan, Mihaela S. title = Protocol for two-arm pragmatic cluster randomized hybrid implementation-effectiveness trial comparing two education strategies for improving the uptake of noninvasive ventilation in patients with severe COPD exacerbation date = 2020-05-06 keywords = COPD; IPE; NIV; hospital summary = title: Protocol for two-arm pragmatic cluster randomized hybrid implementation-effectiveness trial comparing two education strategies for improving the uptake of noninvasive ventilation in patients with severe COPD exacerbation Through a series of mixed-methods studies, we have found that successful implementation of NIV requires physicians, respiratory therapists (RTs), and nurses to communicate and collaborate effectively, suggesting that efforts to increase the use of NIV in COPD need to account for the complex and interdisciplinary nature of NIV delivery and the need for team coordination. The overall objective of this study is to conduct a pragmatic, parallel, 2-arm randomized cluster trial to compare the effectiveness of two implementation strategies: on-line education (OLE) and interprofessional education (IPE) on the uptake of NIV. Hospitals that demonstrate interest in participating in the study will be asked to commit to form a COPD-NIV team composed of one physician, one RT, and one nurse that will be in close contact with the investigators and are responsible for delivering the educational intervention in their institution. doi = 10.1186/s43058-020-00028-2 id = cord-326118-shew7sfw author = Susilarini, Ni Ketut title = Application of WHO’s guideline for the selection of sentinel sites for hospital-based influenza surveillance in Indonesia date = 2014-09-23 keywords = Indonesia; hospital; sentinel summary = title: Application of WHO''s guideline for the selection of sentinel sites for hospital-based influenza surveillance in Indonesia Based on the recently published WHO guideline for influenza surveillance (2012), this study presents the process for hospital sentinel site selection. A checklist was developed based on the WHO recommended attributes for sentinel site selection including stability, feasibility, representativeness and the availability of data to enable disease burden estimation. CONCLUSIONS: The multi-step process enabled sentinel site selection based on the WHO recommended attributes that emphasize right-sizing the surveillance system to ensure its stability and maximizing its geographic representativeness. The guideline also suggests considering the suitability of sites to assess the disease burden of influenza whereby information about the population served by the hospital can be determined to enable disease incidence rate calculation. The WHO guideline was useful as it identified the key attributes to consider in sentinel site selection and it helped address public health decision maker concerns regarding the geographic representation of the surveillance system. doi = 10.1186/1472-6963-14-424 id = cord-344383-7s4gnxs4 author = Tee, Augustine K.H. title = Atypical SARS in Geriatric Patient date = 2004-02-17 keywords = Hospital; SARS summary = We describe an atypical presentation of severe acute respiratory syndrome (SARS) in a geriatric patient with multiple coexisting conditions. On the basis of epidemiologic data (contact tracing linking her to one of the three original index cases in Singapore) (12) , the index patient''s cause of death was determined to be SARS (Figure 3 ). Since the issue of a global alert on atypical pneumonia by the World Health Organization on March 12, reported cases of SARS increased daily and appeared in other countries, including Canada, the United States, Europe, and Africa. Our case serves to highlight atypical signs and symptoms of SARS, especially the resolving fever, delay in establishing a positive contact history, and the nonspecific chest radiographic appearance that could be affected by concurrent coexisting conditions, such as cardiac failure. A cluster of cases of severe acute respiratory syndrome in Hong Kong Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts doi = 10.3201/eid1002.030322 id = cord-314383-1m2xkbok author = Testa, Alexander title = Incarceration Rates and Hospital Beds Per Capita: A Cross-National Study of 36 Countries, 1971-2015 date = 2020-08-03 keywords = health; hospital; incarceration summary = That is, increased emphasis on social control through incarceration will be associated with broader reductions in social support that extend beyond just psychiatric hospitalization and negatively impact other forms of social support including general health care infrastructure. Drawing from a growing body of research that suggests incarceration is a key social institution that impacts population health (Wildeman & Wang, 2017) , as well as a smaller body of research suggesting that incarceration may have spillover effects on healthcare (Schnittker et al., 2015) , the current study investigated whether increases in incarceration rates within countries over time are associated with changes in the number of hospital beds per capita. While this is the first study to examine the relationship between incarceration and hospital bed availability, this result is consistent with the Penrose (1939) hypothesis which is specific to psychiatric hospitalization, as well as prior research on incarceration and health care infrastructure at the sub-national level in the United States (Schnittker et al., 2015) . doi = 10.1016/j.socscimed.2020.113262 id = cord-014533-6qfecv5h author = Velasquez, T. title = ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016 date = 2016-09-29 keywords = AKI; ARDS; CPR; Care; Hospital; ICU; Intensive; group; introduction; method; objective; patient; peep; result; study summary = P. Tirapu; Navarro-Guillamón, L.; Cordovilla-Guardia, S.; Iglesias-Santiago, A.; Guerrero-López, F.; Fernández-Mondéjar, E.; Vidal, A.; Perez, M.; Juez, A.; Arias, N.; Colino, L.; Perez, J. Methods: This descriptive observational study was conducted on consecutive 100 pediatric surgical patients who admitted to PSICUs at Cairo University Hospitals starting from 1/6-1/12/2015.After approval by research ethics committee,informed consents were obtained from parents and pediatric cases aged from 1 month-18 years and stayed for > 48 h were enrolled.MPV and PLC were obtained and recorded at baseline(preoperative values),on the day of ICU admission(day 0),1 st ,2 nd ,3 rd ,5 th and 7 th days.To measure daily MPV changes; (ΔMPV) was constructed and computed where ΔMPV = ([MPVday(X) − MPVday (0)]/MPVday(0) × 100 %. Results: The results obtained after analyzing the two homogeneous groups according to age, gender, type of admission and severity influencing the physiotherapy care in ICU quality indicators, in the Sagrada Esperança clinic, highlights the decrease of the average number of days with mechanical ventilation but it is not observed a significant relation between physical therapy and this indicator (p = 0:06). doi = 10.1186/s40635-016-0100-7 id = cord-348361-a5j067ce author = Verlicchi, Paola title = Trends, new insights and perspectives in the treatment of hospital effluents date = 2020-10-19 keywords = effluent; hospital summary = The most recent literature provides new insights into the occurrence of pharmaceuticals and other contaminants of emerging concern, pathogens, viruses, antibiotic resistant bacteria and genes in hospital effluent in various new developing and developed countries. It also provides information on the effective removal of key compounds (mainly antibiotics, analgesics, beta-blockers and chemotherapy drugs) by means of enhanced biological treatments and advanced oxidation processes. A snapshot of the current situation is provided in a recently-conventional contaminants (the so-called macropollutants) and contaminants of emerging concern (CECs) 48 (mainly pharmaceuticals) in hospital effluent, including antibiotic resistance genes and bacteria (among them 49 (18), (19) . More recently, the efficacy of pathogen and virus removal was at the centre of many debates and 50 studies, and efforts were made to evaluate whether (further) measures should be adopted, and if so which, 51 to reduce the risk of environmental contamination and to guarantee a higher level of hygienisation in the 52 hospital effluent treatment (20), (17) . doi = 10.1016/j.coesh.2020.10.005 id = cord-001215-aj8nxi3x author = Wang, Chen Yu title = One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome date = 2014-01-17 keywords = ARDS; hospital summary = PURPOSE: Advances in supportive care and ventilator management for acute respiratory distress syndrome (ARDS) have resulted in declines in short-term mortality, but risks of death after survival to hospital discharge have not been well described. Our objective was to quantify the difference between short-term and long-term mortality in ARDS and to identify risk factors for death and causes of death at 1 year among hospital survivors. Abstract Purpose: Advances in supportive care and ventilator management for acute respiratory distress syndrome (ARDS) have resulted in declines in short-term mortality, but risks of death after survival to hospital discharge have not been well described. Our objective was to quantify the difference between shortterm and long-term mortality in ARDS and to identify risk factors for death and causes of death at 1 year among hospital survivors. We sought to quantify the survival gap between short-and long-term ARDS mortality and identify risk factors for death and causes of death at 1 year for hospital survivors. doi = 10.1007/s00134-013-3186-3 id = cord-300532-4d6fnjt8 author = Wang, Jiao title = Disinfection technology of hospital wastes and wastewater: Suggestions for disinfection strategy during coronavirus Disease 2019 (COVID-19) pandemic in China date = 2020-04-24 keywords = China; SARS; disinfection; hospital; waste summary = For each ward and restroom of an infectious disease hospital or the infectious disease area of a general Table 1 Comparison of Disinfection technologies for hospital wastewater (Fan et al., 2017; Kühn et al., 2003; Kleinb€ ohl et al., 2018; Messerle et al., 2018; Yu et al., 2013 The ability of decoloring and deodorizing and quick decomposition of microorganisms High operation costs and hazardous by-products hospital, 1 kg of bleaching powder containing 25% of available chlorine per 10 beds should be added 3 to 4 times before further disinfection. From the perspective of investment and operation costs as well as economic and social benefits, high temperature incineration is still one of the most valuable hospital waste disinfection technology in China. Recently, RNA of SARS-CoV-2 has been found in feces of patients, which triggered concern to the disinfection of wastes and wastewater of designated hospitals during COVID-19 pandemic in China. doi = 10.1016/j.envpol.2020.114665 id = cord-311610-uniz8tuc author = Wang, Shi-Yi title = The impact on neonatal mortality of shifting childbirth services among levels of hospitals: Taiwan''s experience date = 2009-06-08 keywords = SARS; hospital summary = This evidence indicates that the neonatal mortality rate in areas with large hospitals was significantly lower than predicted, despite the shift of childbirth services to local community hospitals during the SARS epidemic. Furthermore, this study''s large sample size of 1,848 observations allows us to demonstrate clearly that the shifting of childbirth services among hospitals associated with the SARS epidemic did not increase the risk of neonatal deaths. Although it has not been documented conclusively whether or not advanced hospitals provide better care for normal birthweight deliveries than small maternity units [7] [8] [9] [10] [11] [12] [13] [14] [15] , this study has demonstrated that childbirth outcomes were not influenced by the shift in maternity services to local community hospitals during the SARS epidemic in Taiwan. doi = 10.1186/1472-6963-9-94 id = cord-290524-2el9tx9v author = Weese, J. Scott title = Barrier precautions, isolation protocols, and personal hygiene in veterinary hospitals date = 2004-12-31 keywords = barrier; hand; hospital; isolation summary = Based on universal precautions, infection control practices are applied to all patients, regardless of known or suspected infectious disease status, and emphasize the prevention of any contact with blood or certain body fluids [2] . At the Ontario Veterinary College Veterinary Teaching Hospital (OVC-VTH), a policy requiring glove use for any contact with equine patients was instituted in response to nosocomial and zoonotic transmission of methicillin-resistant Staphylococcus aureus (MRSA). Although no infection control program can eliminate disease concerns, proper implementation of barrier precautions and isolation can reduce the exposure of hospitalized animals and hospital personnel to infectious agents. Although no infection control program can eliminate disease concerns, proper implementation of barrier precautions and isolation can reduce the exposure of hospitalized animals and hospital personnel to infectious agents. doi = 10.1016/j.cveq.2004.07.006 id = cord-256004-rqdeac7h author = Wilcox, Elizabeth S. title = Empowering Health Workers to Protect their Own Health: A Study of Enabling Factors and Barriers to Implementing HealthWISE in Mozambique, South Africa, and Zimbabwe date = 2020-06-23 keywords = Focus; Mozambique; South; Zimbabwe; hospital summary = Through a multiple-case study and thematic analysis of data collected primarily from focus group discussions and questionnaires, we examined the enabling factors and barriers to the implementation of HealthWISE by applying the integrated Promoting Action on Research Implementation in Health Services (i-PARiHS) framework. Overall, successful implementation of HealthWISE required dedicated local team members who helped facilitate the process by adapting HealthWISE to the workers'' occupational health and safety (OHS) knowledge and skill levels and the cultures and needs of their hospitals, cutting across all constructs of the i-PARiHS framework. Results for the four constructs-innovation, recipients, context, and facilitation-are presented below, with quotes that help to reflect what was an enabling factor or barrier in the implementation of HealthWISE in each of the participating hospitals in Mozambique, South Africa, and Zimbabwe. doi = 10.3390/ijerph17124519 id = cord-022473-l4jniccw author = Wilder-Smith, Annelies title = As Travel Medicine Practitioner during the SARS Outbreak in Singapore date = 2009-11-16 keywords = SARS; Singapore; hospital summary = In the first week after our first cases, the WHO named the disease "SARS", and they sent out global alerts. In Singapore, the outbreak was initially only hospital based, but in April the news was out that SARS had affected a large vegetable market. The news of the death of Carlo Urbani, the Italian WHO doctor who was instrumental in the control of SARS in Vietnam, sent our hospital staff into depression. In total, we lost a total of five healthcare workers to SARS in Singapore: 2 doctors, 1 nursing officer, 1 nursing aide and 1 hospital attendant. Two to three weeks into the epidemic it became clear, that infection control measures were effective; no more new cases occurred amongst the staff of our hospital. The SARS outbreak in Singapore can be traced to the first imported case. New imported SARS cases therefore need not lead to major outbreaks if systems are in place to identify and isolate them early. doi = 10.1016/b978-0-08-045359-0.50041-5 id = cord-252050-e71b15vg author = Wu, Jie title = Pharmacy services at a temporary COVID-19 hospital in Wuhan, China date = 2020-05-31 keywords = COVID-19; hospital summary = a To ensure effective treatment of patients with COVID-19 admitted to these COVID-19 ark hospitals, a range of pharmacy services had to be provided, including formulation of a catalog of required drugs, medication supply chain management, storage of drugs, medication dispensing, and evaluation of the effectiveness and safety of drug therapy. The outbreak of COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), 1 emerged in Wuhan, the capital of Hubei Province, in December 2019. 5 As the local epidemic was getting worse, health officials recognized a problem: the growing number of patients with mild COVID-19, whose initial symptoms did not require admission to one of the city''s established acute care hospitals but who might spread the illness among family members if they continued to reside in the community. 7 The COVID-19 ark hospitals, typically housing a medical function unit, ward unit, and technical support unit, provided services ranging from clinical examination to emergency treatment and surgical intervention. Establishing and managing a temporary coronavirus disease 2019 specialty hospital in Wuhan, China doi = 10.1093/ajhp/zxaa160 id = cord-355503-9baof9z8 author = Yan, Aihua title = How hospitals in mainland China responded to the outbreak of COVID-19 using IT-enabled services: an analysis of hospital news webpages date = 2020-04-20 keywords = COVID-19; China; hospital summary = RESULTS: We identified five focal themes across the webpages published by the hospitals during our study period including (1) popular medical science education, (2) digitalized hospital processes, (3) knowledge management for medical professionals, (4) telemedicine, and (5) new IT initiatives for healthcare services. Our analysis revealed that Chinese hospitals spent greater effort in promoting popular medical science education in the initial stages of our study period and more on telemedicine in the latter stages. Based on the 360 events identified in the published hospital pages, five themes emerged on how IT was used to respond to COVID-19, including Theme 1 (T1): dissemination of popular medical science education, Theme 2 (T2): digitalized hospital processes, Theme 3 (T3): Second, the response strategy may contain one or more of these four categories of IT-enabled services, i.e., disseminating popular medical science education, knowledge management for healthcare workers, telemedicine, and digitalized hospital processes. doi = 10.1093/jamia/ocaa064 id = cord-287233-srkny5v4 author = Yu, Hai-ping title = Application of ‘mobile hospital’ against 2019-nCoV in China date = 2020-04-24 keywords = hospital; mobile summary = In this anti-epidemic battle, our hospital adopted the mobile hospital to deal with patients in the early stage of the outbreak in Shanghai and as a supplement medical facility to assist the Wuhan KeTing Medical Shelter. As a temporary facility in the early stage of the outbreak On 23 January, we completed the layout of the mobile hospital fever clinic in just 4 h, which not only effectively deals with fever patients, but also saves precious time for our hospital to complete the formal reconstruction of its fever clinic. From 23 to 27 January, 367 fever patients were registered in the mobile hospital, including one confirmed patient, without any medical staff being infected. The following areas were set up: triage and waiting room, consultation room, laboratory, pharmacy, treatment room (equipped with six infusion chairs), two isolation wards (equipped with beds and mobile toilets) and rest and dressing rooms for medical staff (Figs 1 and 2 ). doi = 10.1017/s0950268820000862 id = cord-351600-bqw9ks4a author = Zhang, Shuai title = Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study date = 2020-07-16 keywords = COVID-19; Hospital; Wuhan summary = title: Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study We aimed to explore the risk factors of 14-day and 28-day mortality and develop a model for predicting 14-day and 28-day survival probability among adult hospitalized patients with COVID-19. Nomogram scoring systems for predicting the 14-day and 28-day survival probability of patients with COVID-19 were developed and exhibited strong discrimination and calibration power in the two external validation cohorts (C-index, 0.878 and 0.839). CONCLUSION: Older age, high lactate dehydrogenase level, evaluated neutrophil-to-lymphocyte ratio, and high direct bilirubin level were independent predictors of 28-day mortality in adult hospitalized patients with confirmed COVID-19. We aimed to explore the risk factors of 28-day mortality and develop a nomogram scoring system for predicting 28-day survival probability among patients with COVID-19. doi = 10.1186/s13054-020-03123-x id = cord-000083-3p81yr4n author = nan title = Poster Exhibition date = 2009-01-31 keywords = ADV; AFP; Background; CHB; China; DNA; ETV; HBV; HCC; HCV; Hepatitis; Hospital; IFN; LAM; NAFLD; NASH; PCR; RFA; RNA; SVR; University; aim; alt; cell; conclusion; group; level; liver; method; patient; result; study; treatment summary = R. China Background: The objective of this study was to evaluate the early virologic response for prediction of achievement of HBeAg seroconversion and hepatitis B virus (HBV) DNA negativity after two years of lamivudine treatment in chronic hepatitis B (CHB) patients. Methods: A total of 620 patients who tested positive for hepatitis B surface antigen and were referred to Chiba University Hospital between February 1985 and March 2008 were included in the study, and their following characteristics were analyzed: age, gender, the status of HBeAg, ALT, HBV-DNA level, and PLT. Methods: A total of 60 patients with chronic hepatitis B, 32 (53.3%) were HBeAg positive (group A) while 28(46.7%) were HBeAg negative (group B) were included in this study after meeting the following criteria: age 18 to 60 years, HBsAg positive for more than 6 months, serum HBV-DNA was >5 log(10) copies/mL and ALT more than two times the upper normal limit. doi = 10.1007/s12072-009-9123-4 id = cord-000718-7whai7nr author = nan title = ESP Abstracts 2012 date = 2012-08-22 keywords = ALK; BRAF; CD10; CD34; CK7; CRC; Dept; EBV; EGFR; HCC; HER2; Hodgkin; Hospital; IHC; KRAS; Ki-67; Ki67; MSI; Medical; NSCLC; Objective; PCR; Pathology; Turkey; University; cancer; carcinoma; case; cell; conclusion; diagnosis; dna; expression; fish; high; method; patient; primary; result; study; tissue; tumor summary = Method: We analyzed consecutive gastric cancer cases in terms of AMACR immunohistochemical expression and clinical/pathological characteristics and followed patients'' postoperative history. Results: Histological, immunohistochemical and molecular examination revealed non-neoplastic lymphadenopathy with atypical paracortical T-cell hyperplasia with immunoblastic reaction in the former and burnt-out histiocytic pattern in the latter, both falling into a broad spectrum of reactive lymph node changes associated with Still''s disease. Method: We have thus collected, from our two Institutions a large number (45 cases) of cancers showing the histological definition of adenosquamous carcinomas according to the WHO criteria and performed gene analysis for k-RAS (codons 12, 13) and EGFR (codons 18, 19 and 21) mutations. Objective: We previously identified amplified fibroblast growth factor 1 (FGFR1) as a therapeutic target for small molecule inhibitor (SMI) therapy in squamous cell lung cancer (L-SCC), resulting in currently running clinical trials treating patients with stage III disease. doi = 10.1007/s00428-012-1284-1 id = cord-003532-lcgeingz author = nan title = 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019 date = 2019-03-19 keywords = AKI; APACHE; ARDS; AUC; Care; Critical; DIC; ECMO; Fig; Hospital; ICU; Intensive; LOS; MAP; conclusion; figure; group; high; introduction; level; method; mortality; patient; result; score; sofa; study; table summary = It''s proposed to evaluate the association between myocardial injury biomarkers, high-sensitive troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-ProBNP), with inflammatory mediators (IL-6, IL-1Β , IL-8, IL-10, IL-12 / IL-23p40, IL17A, IL-21 and TNF-α ) and biomarkers, C protein reactive (CPR) and procalcitonin (PCT), in septic patients Methods: This was a prospective cohort study performed in three intensive care units, from September 2007 to September 2010 enrolling patients with sepsis (infection associated with organ dysfunction), and septic shock (hypotension refractory by fluids infusion requiring vasopressor). Blood samples were collected up to 48h after the development of first organ dysfunction (D0) and on the 7th day after inclusion in the study (D7) Results: Ninety-five patients were enrolled, with median age 64 years (interquatile?48-78), APACHE II: median 19 (14-22), SOFA: median 8 (5-10); 24.2% were admitted in ICU with sepsis and 75.8% with septic shock. doi = 10.1186/s13054-019-2358-0 id = cord-005105-twsy61oq author = nan title = SIU 2015 Abstracts date = 2015-09-21 keywords = ADT; BPH; ESWL; Gleason; Group; Hospital; IPSS; Introduction; January; LUTS; MRI; Objective; PCNL; PSA; Prostate; RARP; TRUS; aft; bladder; case; conclusion; follow; mean; method; patient; renal; result; score; signifi; study; treatment; urinary; year summary = Th e present study is based on a retrospective analysis of a database of over 600 patients (age range 17-57 years) who met the consensus criteria for bacterial prostatitis, 75% of whom had dysuria, 35% perineal discomfort, 60% had obstructive luts, 37% infertility of unknown etiology, 10% erectile dysfunction and 25% recurrent infection of the partner. Further research is needed to determine to assess whether localization of small volume disease on 68Ga-PSMA PET/CT can improve diagnostic algorithms and outcomes in patients with recurrent PCa. Introduction and Objective: To assess long-term results of salvage pelvic lymph node dissection (PLND) in prostate cancer (PC) patients (pts) with biochemical recurrence aft er primary local treatment and confi rmed solitary lymph node (LN) metastases. doi = 10.1007/s00345-015-1684-3 id = cord-005453-4057qib7 author = nan title = The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians – Poster Session date = 2019-07-03 keywords = AML; ASCT; ATG; BMT; CD19; CD34; CD4; CD8; CMV; CSF; DFS; DLI; EBMT; EBV; ECP; GVHD; HCT; HLA; HSCT; Hodgkin; Hospital; III; January; MDS; MRD; MSD; NHL; NRM; PBSC; PCR; PFS; PNH; RIC; TBI; TMA; TRM; University; VOD; background; car; cell; conclusion; day; disease; donor; figure; graft; group; high; median; method; mud; patient; result; transplantation summary = To compare the safety and efficacy of prophylactic DLI for prevention of relapse after allogeneic peripheral blood stem cell transplantation from haploidentical donors (HID-SCT) and matched-sibling donors (MSD-SCT) in patients with very high-risk acute myeloid leukemia (AML), we performed a retrospective, observational cohort study enrolled in 21 HID-SCT and 13 MSD-SCT recipients. The aim of this study is to identify the prognostic impact of pre-transplant TIM3 levels on early and late transplant related complications as well as post-transplant relapse and survival Methods: A total of 177 hematopoietic stem cell transplantation (HSCT) recipients with an initial diagnosis of acute leukemia [median age: 36(16-66) years; male/ female: 111/66] were included in the study. doi = 10.1038/s41409-019-0559-4 id = cord-005460-ezrn8cva author = nan title = Physicians – Poster Session date = 2017-07-28 keywords = AML; ASCT; ATG; BEAM; CD34; CD4; CD8; CMV; CSF; DFS; DLI; Department; EBV; ECP; GVHD; HCT; HLA; HSCT; Hematology; Hodgkin; Hospital; III; January; MDS; MRD; MSC; NHL; NRM; PBSC; PCR; PFS; RIC; SOS; TBI; TRM; Table; University; VOD; cell; day; figure; patient; transplantation summary = Still the optimal combination of immunosuppressive agents with PTCy should be elucidated for different types of SCTs. We report the 2-year update of the prospective NCT02294552 single-center trial that evaluated risk-adapted graft-versushost disease (GVHD) prophylaxis with PTCy in related, unrelated and haploidentical SCTs. 200 adult patients (median age 32 y.o., range: 18-62) with hematologic malignancies, including AML (47.5%), ALL (26.5%), CML (10.5%), MDS (4%), and lymphomas (11.5%), were enrolled in the study. Long-term follow-up from the prospective randomized phase III multicenter trial comparing a standard GvHD prophylaxis with cyclosporine A and methotrexate with or without additional pretransplant ATLG (Grafalon, previously ATG-FRESENIUS S) (given 20 mg/kg/day, days − 3 to − 1) in unrelated donor hematopoietic cell transplantation after myeloablative conditioning resulted in a significant reduction of acute and chronic GvHD without compromising relapse rate and survival [1, 2, 3] . doi = 10.1038/bmt.2017.134 id = cord-005497-w81ysjf9 author = nan title = 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date = 2020-03-24 keywords = AKI; AUC; CRP; CRRT; Care; Critical; ECMO; Fig; Hospital; ICU; IQR; Intensive; LOS; LPS; OHCA; PCT; ROC; TBI; Unit; University; VAP; blood; day; figure; group; high; introduction; mortality; patient; result; sepsis; sofa; study; table summary = The positive NC group had more plasma transfusion (p-value 0.03) and a lower median hematocrit at 24 hrs (p-value 0.013), but similar hospital length of stay (p=0.17) and mortality rate (p=0.80) Conclusions: NC at ICU admission identifies subclinical AKI in TBI patients and it maight be used to predictclinical AKI. In patients with pneumonia requiring intensive care (ICU) admission, we hypothesise that abnormal right ventricular (RV) function is associated with an increased 90-day mortality. The objective of this study was to describe the incidence of each AKI stages as defined by KDIGO definition (with evaluation of urine output, serum creatinine and initiation of renal replacement therapy (RRT)), in a mixed medical and surgical population of patients hospitalized in ICU and PCU over a 10-year period (2008-2018). This study aimed at investigating the relationship of goal-directed energy and protein adequacy on clinical outcomes which includes mortality, intensive care unit(ICU) and hospital length of stay (LOS), and length of mechanical ventilation (LOMV). doi = 10.1186/s13054-020-2772-3 id = cord-005646-xhx9pzhj author = nan title = 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date = 1996 keywords = ARDS; CPB; Care; Children; ECMO; Hospital; ICU; Intensive; PICU; Pediatric; Unit; age; blood; case; child; conclusion; day; failure; group; high; hour; increase; infant; level; mean; method; patient; prism; pulmonary; respiratory; result; severe; study; ventilation; year summary = Aims and methods The aim of both a prospective and retrospective survey conducted in German pediatric intensive care units in 1993 was to accumulate data on the epidemiology, risk factors, natural history and treatment strategies in a large group of pediatric ARDS patients who were treated in the tt~ee year period from 1991 to 1993.All patients had acute bilateral alveolar infiltration of noncardiogenic origin and a pO2~iO2 ratio < 150mmHg. The influence of sex, underlying disease and single organ failure was analyzed using the Fischer''s exact test, the influence of additional organ failure on mortality was tested with the Cochran-Mantel-Haenszet statistics. doi = 10.1007/bf02316512 id = cord-005727-li8pwigg author = nan title = ESICM 2010 MONDAY SESSIONS 11 October 2010 date = 2010-08-31 keywords = AKI; APACHE; CRP; Care; GCS; Hospital; ICP; ICU; Intensive; January; LPS; NIV; PCT; Unit; University; VAP; conclusion; day; group; introduction; method; objectives; patient; result; sofa; study summary = Since, continuous epidural analgesia provides the required level of analgesia to support early mobilization and significant reduction in pulmonary and cardiovascular morbidity in the early postoperative period, we postulated that the use of low dose of continuous epidural morphine might improve postoperative analgesia and reduce undesirable side effects in elderly patientsTherefore, the present study was designed to evaluate the effects of morphine administered via epidural patients controlled analgesia and intravenous tramadol + metamizol on postoperative pain control and side effects in elderly patients after major abdominal surgery. For each ventilated patient the following data was registered:Age, APACHE II, the reason of admission, risk factors, use NIV, MV duration, timing of tracheostomy, time of diagnosis of VAP, microbiological data, length of stay and mortality in ICU. 23rd ESICM ANNUAL CONGRESS -BARCELONA, SPAIN -9-13 OCTOBER 2010 S131 Evaluated factors: patient characteristics, signs, symptoms, abscess location, time between symptoms and hospital admission and surgery, lab results, microbiology, antibiotic therapy, APACHE2, SAPS2, SOFA, length of ICU stay, surgical re-intervention, duration of mechanical ventilation, infectious complications, critical illness myopathy (CIM), renal replacement therapy (RRT), re-intubation, tracheotomy, mortality. doi = 10.1007/s00134-010-1999-x id = cord-005777-6rvfsx4p author = nan title = PS 0420-0716 date = 2007-08-25 keywords = APACHE; ARDS; CVVH; Care; GCS; Glasgow; Hospital; ICP; ICU; Intensive; TEG; VAP; conclusion; day; group; mean; method; mortality; patient; peep; result; study summary = We prospectively recorded data of all patients who were newly diagnosed with AF and all those with a septic shock on a surgical ICU (no cardiac surgery) during a one year period according to the requirements of the local ethical committee. Our aim was to evaluate the predictive role of admission APACHE II, admission and total maximum SOFA score, hypoalbuminemia, increased serum creatinine, C-reactive protein, lactate, and serum blood glucose for the 30-day mortality of septic patients admitted to medical ICU. The aim of this study was to analyze the clinical presentation and to evaluate mortality associated factors (timing and accurancy of diagnosis, timing of surgery, severity score and organ failure, surgical and medical treatments). Data were extracted independently to assess intention to treat intensive care unit (ICU) and hospital mortality, days of mechanical ventilation, length of stay, incidence of ventilator-associated pneumonia and pneumothorax, and associated complications of the implemented intervention. doi = 10.1007/s00134-007-0823-8 id = cord-005814-ak5pq312 author = nan title = 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date = 1995 keywords = AMI; APACHE; ARDS; ARF; COPD; CPB; CPR; CVP; Care; ECG; ECMO; Group; H20; Hospital; ICP; ICU; III; IL-6; Intensive; January; LPS; MOF; PSV; SAPS; TNF; Unit; University; acute; blood; cardiac; change; conclusion; control; day; effect; failure; follow; high; hour; increase; level; mean; measure; method; mortality; objective; patient; peep; pressure; pulmonary; respiratory; result; study; treatment; value summary = Results: In 5 patients with treated SS, 16 tests were performed (VL n=8; Dobu n=4; NA n=4 Method: Septic shock was defined as severe sepsis with either persistent hypotension (mean arterial pressure; MAP<70 mmHg) or the requirement for a noradrenaline (NA) infusion ~> 0.1 ~g/kg/min with a MAP _< 90mmHg. Cardiovascular support was limited to NA + dobutamine (DB), 546C88 was administered for up to 8 h at a fixed dose-rate of either i, 2.5, 5, 10 or 20 mg/kg/h iv. Methods: Fourteen cases were s~udied,their gestational age ranged from(27-32)ws.Continnous positive air way pressure was applied to six cases at Peep level from (3-6)cm H2o through nasal pronge,(group I),the other 8 cases were managed as routine,(group II).Blood gases, TcPO2,TcCo2,resp.rate,depth and pattern were monitored for assessment of tissue Oxygenation and ventilation, Results: Our rasults showed that early application of CPAP improve ventilation among (83.3%)of cases,while (16.7%)of cases need IMV.The cases of group II need IMV among (75%)of the studied cases during the second or the third day of life. doi = 10.1007/bf02426401 id = cord-005816-i54q5gsu author = nan title = 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date = 2009-08-06 keywords = Department; GCS; Hospital; ICU; ISS; Istanbul; January; Turkey; University; abdominal; case; conclusion; day; fracture; group; injury; introduction; method; mortality; patient; result; score; study; surgery; trauma; treatment; year summary = Several factors such as the initial lack of symptoms, a low diagnostic sensitivity of the CT (34% false negatives), and the nonoperative management of solid organ injuries, have contributed to a delayed diagnosis in one of every five patients in our series, but this has not led to a significant increase in septic complications in this group. Method: The demographic features, the treatments, the intensity of the illness and mortality rate of the 155 patients in Afyon Kocatepe University General Surgery clinic between the years 2006 Background: Enterocutaneous fistula continues to be a serious surgical problem. Introduction: In our previous study, we examined the treatment results of burn patients older than 45 years, and found a significant increase in mortality with increasing age groups. Methods: Data on emergency surgical cases and admissions to the surgical service over a 3-month period were collected and analyzed; this included patient demographics, referral sources, diagnosis, operation, and length of stay (LOS Conclusion: Emergency workload represents a significant part of the work for the general surgeons. doi = 10.1007/s00068-009-8001-z id = cord-005881-oswgjaxz author = nan title = Abstracts: 11(th) European Congress of Trauma and Emergency Surgery May 15–18, 2010 Brussels, Belgium date = 2010 keywords = Hospital; ICU; ISS; case; complication; conclusion; follow; fracture; group; high; injury; introduction; material; mean; method; patient; result; score; screw; significant; study; surgery; trauma; treatment; year summary = Prospective case series with historical control group.(Level III) Results: Preliminary data indicate: *a shorter time on ventilator than anticipated (based on comparisson to historical data) * a shorter time on ICU * less pneumoniae * no intra-operative complications * good healing results of the rib fractures * no implant failures * acceptable pain scores * good overal satisfaction * acceptable cosmetic results Conclusion: Internal fixation of rib fractures (flair chest or multiple sequential fractures with pulmonary function compromise) results in a earlier recuperation of pulmonary function with shortened ICU stay. (Regional Association Sanitary Emergencies) Material and Methods: The ARES, whose members are about 600, all over the nation, is configured as an extraordinary health resource, activated by the National Civil Defence operations centre, in according with the Regional centre of Marche, in disater situations Results: The main objectives of ARES are training and organization of medical staff and structures and its growth crosses several missions including: AE Earthquake in Molise, 2002 Introduction: Cephalomedullary nails rely on a large lag screw that provides fixation into the femoral head. doi = 10.1007/s00068-010-8888-z id = cord-006702-ekf6mja9 author = nan title = Abstracts for the 17th IPNA Congress, Iguaçu, Brazil, September 2016: Oral Presentations date = 2016-08-17 keywords = CKD; Hospital; Objectives; UTI; University; VUR; child; patient; result; study summary = After correction using the optimal linear regression, the variability of the measurements was examined using Bland-Altman plots Results: We studied 29 patients (17 male, 12 female) with a median age (SD) of 14.0 (3.4) years and eGFR 111 (17) Objectives: Mutations of the Pkhd1 gene cause autosomal recessive polycystic kidney disease (ARPKD). Objectives: To examine the characteristics, follow up and availability of long term outcome data in a cohort of New Zealand children with acute kidney injury (AKI) requiring renal replacement therapy (RRT) following cardiac surgery at Starship Hospital over a six-year period. Methods: Cohort study conducted from 2008-2012 of 57 female patients age 9-21 years recruited from 2 pediatric nephrology clinics with CKD (n=25), on dialysis (n=9), or status post kidney transplantation (n=23) who received the standard 3-dose vaccine series of the HPV vaccine. doi = 10.1007/s00467-016-3466-6 id = cord-006849-vgjz74ts author = nan title = 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date = 2019-09-13 keywords = BMI; December; ERCP; Endosc; GERD; Hospital; ICG; January; Japan; MRI; Medical; Nissen; November; TME; University; aim; approach; cancer; case; complication; conclusion; day; gastric; group; hernia; laparoscopic; method; patient; perform; postoperative; procedure; resection; result; robotic; roux; study; surgery; surgical; time; treatment; year summary = Methods: We are performing this procedures within a prospective randomized trial that is design to compare the long term results of LRYGB-B versus the standard laparoscopic Roux-en-Y gastric bypass.The video shows our technique in a case of a 46 years old female with a BMI of 46 Kg/m2. Material and methods: We present a video of the surgical intervention of a 32-year-old patient, with functional dyspepsia, with a casual diagnosis of a pseudocystic mass of the right colon after performing a CT scan: giant diverticulum of the hepatic colon angle with fecaloid content inside it under tension The patient goes to the emergency room for acute abdominal pain, pending colonoscopy, antibiotic treatment is established, and a laparoscopic approach is decided upon after the patient''s evolution. Method: We present the case of a 65-year-old patient with surgical antecedent of laparoscopic low anterior resection due to rectal cancer, presenting in postoperative period an anastomosis leakage with severe peritonitis was identified and a laparotomy with end colostomy was performed. doi = 10.1007/s00464-019-07109-x id = cord-006854-o2e5na78 author = nan title = Scientific Session of the 16th World Congress of Endoscopic Surgery, Jointly Hosted by Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) & Canadian Association of General Surgeons (CAGS), Seattle, Washington, USA, 11–14 April 2018: Poster Abstracts date = 2018-04-20 keywords = BMI; CBD; Center; ERCP; FLS; GERD; Hospital; ICG; January; LOS; LSG; Medical; RYGB; SILS; University; case; complication; conclusion; follow; gastric; group; hernia; introduction; laparoscopic; method; operative; outcome; patient; postoperative; procedure; rate; report; result; robotic; roux; study; surgeon; surgery; surgical; time summary = Totally Laparoscopic ALPPS Combined with the Microwave Ablation for a Patient with a Huge HCC Hua Zhang; Department of Hepatopancreatobiliary Surgery, West China Hospital, Sichuan University Introduction: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel technique for resecting hepatic tumors that were previously considered unresectable due to the insufficient future liver remnant (FLR) which may result in postoperative liver failure (PLF). Not only does this case show that a large epiphrenic diverticulm can be successfully resected via the trans-abdominal laparoscopic approach, this case makes the argument that patients undergoing any minimally-invasive epiphrenic diverticulectomy and myotomy, with or without fundoplication, may be successfully managed with early post-operative contrast studies and dietary advancement, thus decreasing their length of hospitalization and overall cost of treatment. Introduction: There are reports of increased operative duration, blood loss and postoperative morbidity, caused by difficulties in obtaining good visualization and in controlling bleeding when laparoscopic resection is performed in obese patients with colon cancer. doi = 10.1007/s00464-018-6121-4 id = cord-006862-5va1yyit author = nan title = ITS ASM 2012 date = 2012-11-04 keywords = AAT; AATD; COPD; Hospital; IPF; Ireland; OSAS; disease; lung; patient; study; year summary = 10 .45 % (n = 202) of attendances were for non-respiratory diseases as the clinic also provides follow-up for general medical patients post hospital admission. Higher levels of exercise participation were seen in the younger age groups (p = 0.585 Introduction: Respiratory diseases, largely represented by COPD, are the third most common cause of acute hospital admission.Our aim was to audit the prescribing habits of inhaled, nebulised medication and oxygen by doctors in a general hospital. Our study was designed to determine the baseline and post-treatment values of total lymphocyte count and its subsets in HIV-negative patients diagnosed with active pulmonary MTB. The results of this study indicate that AAT can inhibit LTB 4 signaling thereby reducing the proteolytic activity of neutrophils and propose AAT aerosolized augmentation therapy as an effective treatment for LTB 4 associated pulmonary diseases including cystic fibrosis and severe asthma. doi = 10.1007/s11845-012-0856-z id = cord-006882-t9w1cdr4 author = nan title = Royal Academy of Medicine in Ireland date = 2012-07-22 keywords = DEXA; Hospital; case; disease; medical; patient; study; year summary = Objective: The aim of this study was to develop a mathematical model to determine the TTO based on two or more DEXA scans with TTO defined as the age at which the patient will enter the osteoporotic T-score range. An Audit of Clinical Outcomes in Transcervical Resection of the Endometrium Compared to Outpatient Balloon Thermablation Anglim BC, Von Bunau G Department of Gynaecology, Adelaide and Meath Children''s Hospital, Tallaght, Dublin Thermablation was introduced to the Coombe in November 2009 and thus far it has provided a quick and effective means of treating women with menorrhagia refractive to medical treatment. This audit reviewed cases of ovarian cystectomy, oopherectomy and salpingooopherectomy using both a hospital online database and records of theatre procedures to identify these patients. A retrospective review of the case notes of patients aged greater than 80 years who underwent bronchoscopy between September 2009 and November 2011 was carried out. doi = 10.1007/s11845-012-0833-6 id = cord-006888-qfnukav4 author = nan title = Irish Thoracic Society Annual Scientific Meeting, Ramada Hotel, Belfast: 7th–8th November 2008 date = 2008-10-21 keywords = A1AT; AAT; COPD; FEV1; Hospital; Ireland; LPS; OSA; Society; TBNA; lung; patient; study summary = 2 This study explored anxiety, depression and QoL of a small group of patients (n = 5), predominantly male (66.7%), mean age 74 years, using the Marie Curie ''''breathing space'''' outpatient clinic over a four week period. Methods: CF patients attending CUH completed a questionnaire relating to personal smoking and second-hand smoke (SHS) exposure, correlated with pulmonary function and exacerbation-rate data. This ongoing study indicates that a clinical pharmacy led management programme can reduce the need for hospital care in patients with moderate-to-severe COPD and improve aspects of their health related quality of life. There is a need for wider availability of joint hospital/ community based initiatives such as COPD Outreach and PRPs. Pulmonary rehabilitation has established efficacy, but patients often require follow-up care or maintenance. Patient data (MDS/ISWT/endurance shuttle walking test(ESWT)) from our pulmonary rehabilitation programme were initially analysed (n = 214; median FEV 1 = 1.04 L; mean age = 69 yrs). doi = 10.1007/s11845-008-0235-y id = cord-007890-bie1veti author = nan title = ECC-4 Abstracts date = 2002-04-16 keywords = Department; Diseases; ESBL; France; HAART; HCV; HIV; Hospital; IFN; Infectious; Institute; MIC; MRSA; Medical; Medicine; Microbiology; NCCLS; PCR; Purpose; RNA; Spain; Staphylococcus; University; gram; isolate; patient; resistance; result; strain; study summary = Effects of Interferon alpha plus ribavirine therapy on frequencies of HCV, HIV and CMV specific CD4-T-cell responses in peripheral blood of HIV/HCV coinfected patients after 6 months of treatment SoA9.5 Methods: Two groups of patients with chronic HCV infection were studied: 26 HIV coinfected progressors with antiretroviral therapy and 13 HIV-negative controls. In order to assess the local temporal trend of antibiotic sensitivity of the most common urinary tract bacterial pathogen, all urine-cultured Escherichia coli isolates were reviewed as to susceptibility profile, and specimen source (community-versus hospital-acquired infection). Methods: A total of 87 penicillin resistant clinical strains isolated from patients at Hacettepe Children''s Hospital, Ankara, Turkey between 1999 and 2001 were tested for their in vitro susceptibility to various antibiotics that are commonly used in the treatment of respiratory tract infections. doi = 10.1016/s0924-8579(02)00033-x id = cord-009713-sxd4t2tz author = nan title = Poster Presentations date = 2020-01-10 keywords = CSF; Children; DMD; EEG; Hospital; MRI; Neurology; Paediatric; age; case; child; conclusion; patient; present; report; result; seizure; study; year summary = Poster No. 010 Seizure, developmental and cognitive outcomes in children post hemispherotomy TT TAY 1 , DR REED 2 , VJ JOSAN 3 , SR RUST 4 , JT TAN 5 1 University of Manchester, Manchester, UK; 2 Neuropsychology Team, Paediatric Psychosocial Service, Royal Manchester Children''s Hospital, Manchester, UK; 3 Neurosurgery, Salford Royal NHS Foundation, Manchester, UK; 4 Paediatric Neuropsychology, Royal Manchester Children''s Hospital, Manchester, UK; 5 Paediatric Neurology, Royal Manchester Children''s Hospital, Manchester, UK Introduction: Patients with focal refractory epilepsy secondary to structural hemispheric changes have been shown in retrospective studies to have significantly improved seizure outcomes following hemispheric disconnection. In a univariate analysis of 682 cases with ≥12 months follow-up data, poor final outcome (defined as modified Rankin Scale [mRS] score 3-6) occurred in 30% and was associated with very young or elderly age at onset, movement disorder, decreased consciousness, autonomic dysfunction, mechanical ventilation, higher mRS score in the acute phase, longer hospital stay, extreme delta brush on EEG, abnormal MRI, CSF pleocytosis and elevated CSF protein (all p<0.05). doi = 10.1111/dmcn.14411 id = cord-009997-oecpqf1j author = nan title = 2018 ASPHO ABSTRACTS date = 2018-03-31 keywords = AKI; AML; AYA; BRAF; Background; CNS; Cancer; Center; Children; EBV; GVHD; Group; HLH; HSCT; Hospital; January; MRD; MRI; Medical; Method; S301; SCD; States; TCD; United; University; VOC; VTE; cell; child; disease; high; patient; pediatric; result; study; therapy; treatment; tumor; year summary = Completed cranial radiation and proceeded to allogeneic stem cell transplant with unrelated cord marrow donor and is disease free at approximately day +200.Case 2: 5 year-old female diagnosed with FLT3 and MLL negative AML and completed treatment per COG AAML1031 study on the low risk arm without Bortezomib. Design/Method: This study was a retrospective chart review that included patients 3 to 23 years old with sickle cell disease type SS and S 0 followed at St. Christopher''s Hospital for Children. Background: Hydroxyurea, chronic blood transfusion, and bone marrow transplantation can reduce complications, and improve survival in sickle cell disease (SCD), but are associated with a significant decisional dilemma because of the inherent risk-benefit tradeoffs, and the lack of comparative studies. Brown University -Hasbro Children''s Hospital, Providence, Rhode Island, United States Background: Despite clinical advances in the treatment of sickle cell disease (SCD) in pediatric and young adult patients, pain remains a significant source of disease-related morbidity. doi = 10.1002/pbc.27057 id = cord-010027-r0tl01kq author = nan title = Dublin Pathology 2015. 8th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland date = 2015-09-15 keywords = EQA; FFPE; Hospital; IHC; Ireland; NGS; PCR; University; cancer; case; cell; diagnosis; dna; expression; patient; result; study; tumour summary = Further profiling of other T cell populations may help to further understand this expression which may act as a biomarker or provide a therapeutic target Biomarkers that are able to distinguish stage II and III colon cancer patients at high risk of developing disease recurrence, who may benefit from adjuvant chemotherapy, are still lacking. *AM supported by the NIHR and the Academy of Medical Sciences ABSTRACTS S·17 Assessment of HER2 Status on Needle Core Biopsy of Breast Cancer: Impact of Histopathological Concordance P M Pigera; AHS Lee; IO Ellis; EA Rakha; Z Hodi Nottingham City Hospital, Nottingham, UK One of the key recommendations introduced in the ASCO/CAP update guideline recommendation on HER2 testing is the novel concept of "histopathological concordance." It is proposed that certain tumour morphological features such as histologic type and grade should trigger repeating a molecular test in cases of "discordance". doi = 10.1002/path.4631 id = cord-010092-uftc8inx author = nan title = Abstract of 29th Regional Congress of the ISBT date = 2019-06-07 keywords = ABO; AIHA; Alinity; Background; Blood; CD34; Conclusions; DAT; December; HBV; HCV; HDFN; HEV; HIV; HLA; Health; Hospital; January; NAT; National; PBM; PCR; PLT; RBC; RHD; RNA; Red; SCD; Service; Summary; Transfusion; aim; anti; cell; dna; donation; donor; group; method; patient; platelet; result; sample; study; test summary = Prospective testing of blood donations in endemic areas of the U.S. revealed 0.38% of donors were positive for Babesia DNA or antibodies (Moritz, NEJM, 2016) Aims: -To report results of ongoing Babesia clinical trial -To explain significance of Babesia as a TT infection Methods: In cobas â Babesia for use on the cobas â 6800/8800 Systems, is a qualitative polymerase chain reaction nucleic acid amplification test, developed to detect in whole blood (WB) donor samples the 4 Babesia species that cause human disease: B. In sensitivity analyses, there were two discrepant results for HIV testing, three for HCV, and five for anti-HBc. Summary/Conclusions: Elecsys â infectious disease parameters on the cobas e 801 analyser demonstrate high specificity/sensitivity for screening first-time blood donor samples, with similar clinical performance to other commercially available assays. doi = 10.1111/vox.12792 id = cord-010119-t1x9gknd author = nan title = Abstract Presentations from the AABB Annual Meeting San Diego, CA ctober 7‐10, 2017 date = 2017-09-04 keywords = ABO; Anti; Background; Blood; CD36; Case; Center; DAT; DTT; Design; FDA; FFP; HBV; HCV; HIV; HLA; Hospital; IPC; MTP; Medical; Medicine; NAT; PCR; PLT; RBC; RHD; Red; Studies; Study; System; TPE; University; WBC; ZIKV; Zika; cd341; cell; conclusion; day; dna; donor; finding; method; patient; platelet; result; sample; table; test; transfusion; type summary = Conclusion: The wide distribution in the concentration of bioactive lipids among 405 stored RBC units suggests that lipid degradation is highly donor-Background/Case Studies: To ensure availability of biological products to hospitals, blood banks have developed and validated multiple storage conditions for each of their products to maximize shelf life and quality. 1 The Department of Blood Transfusion, The PLA General Hospital, 2 The Department of Blood Transfusion, Air Force General Hospital, PLA Background/Case Studies: Recently, multi researches have reported that longer term-stored red blood cells(RBCs) units were associated with increased risks of clinically adverse events, especially in critically ill patients. Weak D types 1, 2 and 3 express all the major RhD epitopes and these patients can be managed as RhD-positive, which may lead to a reduction in unnecessary Rh immunoglobulin (RhIG) administration and conservation of RhD-negative RBCs. Study Design/Method: RHD genotyping was performed on all patient samples with weaker than expected or discrepant RhD typing results, utilizing a commercially available genotyping kit manufactured by Immucor (RHD BeadChip). doi = 10.1111/trf.14286 id = cord-010980-sizuef1v author = nan title = ECTES Abstracts 2020 date = 2020-05-11 keywords = AIS; Department; Emergency; Fig; GCS; Hospital; ICU; ISS; January; Japan; MCI; Progressions; REBOA; TBI; Trauma; University; case; clinical; conclusion; fracture; group; injury; introduction; material; method; mortality; patient; result; retrospective; score; study; surgery; treatment; year summary = We hypothesized that presentation to a PTC would yield increased mortality when subspecialty intervention was required and that this would be most pronounced at night when in-house attending coverage is absent at all state PTCs. Materials and methods: A review of the Pennsylvania Trauma Outcome Study (PTOS) database was performed to capture patients aged 12-18 who underwent any non-orthopedic trauma surgery. Traumatic subaxial cervical fractures: functional prognostic factors and survival analysis Introduction: The main goal of this study is to identify the risk factors for poor functional outcomes and to analyze the overall survival (OS) and complications rate in patients with traumatic cervical spinal cord injury (SCI) and subaxial cervical fracture (SACF) treated with open surgical fixation. After applying a multiple imputation on all the study variables, a logistic regression generalized estimating equation after adjustment for age, sex, mechanism of trauma, and the injury severity score as covariates and hospitals as a cluster assessed an association between quartile of patient volume in intensive care unit and hospital mortality. doi = 10.1007/s00068-020-01343-y id = cord-011062-ukz4hnmy author = nan title = Poster date = 2020-03-11 keywords = BMI; Center; DXA; Department; Fried; Geriatric; Group; Health; Hospital; Index; Japan; MNA; SPPB; Sarcopenia; University; adult; age; background; frailty; low; method; muscle; objective; old; patient; physical; result; study; year summary = Ming-Yueh Chou 1,3 , Ying-Hsin Hsu 1 , Yu-Chun Wang 1 , Chih-Kuang Liang 1,3 , Li-Ning Peng 2,4 , Liang-Kung Chen 2,4 , Yu-Te Lin 1 ((1) Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; (2) Aging and Health Research Center, National Yang Ming University, Taipei, Taiwan; (3) Department of Geriatric Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan; (4) Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan) Background: Older people with frailty are at risk of adverse outcomes, such as falls, functional decline and mortality, and multi-domain intervention program may prevent those. Conclusion: Our study showed that a multicomponent exercise program is effective for posthospitalization patients because after 24-week intervention there were significant reductions in frailty and improving results in muscle strength and physical performance. Methods: Cross-sectional analysis of 757 communitydwelling older adults who completed multi-domain geriatric screen assessing for social vulnerability, mood, cognition, functional performance, nutrition, physical frailty (FRAIL) and sarcopenia (SARC-F). doi = 10.14283/jfa.2020.9 id = cord-014670-e31g8lns author = nan title = Poster Sessions 313-503 date = 2004-10-05 keywords = APACHE; Care; Hospital; ICP; ICU; Intensive; Unit; University; conclusion; group; patient; study summary = doi = 10.1007/s00134-004-2406-2 id = cord-014687-0am4l5ms author = nan title = SPR 2012 date = 2012-03-29 keywords = ACR; ADC; Administration; Case; Center; Children; College; DWI; Dr.; Drug; FDA; Food; Hospital; Imaging; MDCT; MRI; Materials; Medical; NF1; PET; Pediatric; Purpose; Radiology; Report; SPR; Society; University; child; clinical; conclusion; diagnosis; finding; image; patient; result; review; study summary = This presentation will focus on recent developments that have lead to a better understanding of the embryopathogenesis for fibropolycystic liver diseases (including choledochal cysts and Caroli disease), histopathological findings that have led to new classification systems for of pediatric vascular anomalies, technological advances and contrast agents in magnetic resonance imaging that are useful to characterize and limit the differential diagnosis of hepatic masses. Disclosure: Dr. Annapragada has indicated that he is a stock holder and consultant for Marval Biosciences Inc. Paper #: PA-067 Cardiovascular Image Quality Using a Nanoparticle CT Contrast Agent: Preliminary Studies in a Pig Model Rajesh Krishnamurthy, Radiology, Texas Children''s Hospital, rxkrishn@texaschildrens.org; Ketan Ghaghada, Prakash Masand, Abhay Divekar, Eric Hoffman, Ananth Annapragada Purpose or Case Report: Image quality in a separate study using a long circulating, liposomal-based nanoscale blood pool iodinated contrast agent (NCTX) suggests clinical utility in pediatrics, potentially reducing difficulties in contrast-CT of children with congenital heart disease (CHD) including the size of intravenous cannula, need for accurate timing, inability to simultaneously opacify multiple targets of interest (requiring repeated contrast administration and/or repeated imaging). doi = 10.1007/s00247-012-2356-8 id = cord-014712-5u4e00q6 author = nan title = Selected Abstracts from the 100th J Project Meeting, Antalya, Turkey, March 12-14, 2014 date = 2014-08-02 keywords = BCG; CGD; CVID; HSCT; Hospital; IVIG; Immunology; PID; SCID; University; case; cell; deficiency; disease; dna; infection; patient; year summary = Ege University Faculty of Medicine, Dept of Pediatric Immunology, Izmir, Turkey Ig class switch recombination deficiencies are rare PIDs (1:500,000 births) with normal or elevated serum IgM and low IgG, IgA and IgE levels, defective or normal somatic hypermutation, defective T/B cooperation (50%), intrinsic B cell defect (50%), susceptibility to bacterial infections begining from the first year of age (impaired B cell immunity) and lack of germinal centres in secondary lymphoid organs. Great North Children''s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, and Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK Even following the introduction of biologic disease modifying antirheumatic drugs (DMARDs), a small number of children suffering from severe, refractory autoimmune (AI), rheumatic and/or autoinflammatory disorders will not get into clinical remission (CR) and will potentially further suffer from multiple side-effects of combined and long-term immunosuppressive and anti-inflammatory therapies, in particular severe infections (Marodi L, Casanova JL. doi = 10.1007/s10875-014-0065-9 id = cord-014794-yppi30a0 author = nan title = 19th European Congress of Pathology, Ljubljana, Slovenia, September 6-11, 2003 date = 2003-07-31 keywords = Bcl-2; CD10; CD30; Department; FNA; HCC; Hospital; IHC; III; Institute; Introduction; Ki-67; Ki67; Medical; Medicine; NHL; PCNA; PCR; Pathology; University; VEGF; aim; cancer; carcinoma; case; cell; conclusion; diagnosis; dna; expression; group; high; hpv; lesion; material; method; patient; positive; result; study; tissue; tumor summary = These parts were in a high percentage associated with fibrosis and lymphocyte rich areas and showed a higher mitotic activity than usual PTCs. Discussion The differences in the occurrence of TCV and TCmorphology between the presented series and previously reported cases might result from until now not clearly defined tall cell morphology as well as from similarities to PTCs, such as the oxyphilic variant, which is extremely rare in our series, and maybe also from often described squamous changes within PTCs. Due to these data it is not clear which tumor parts have relevance for prognosis and which tumors should be treated more aggressively than others. The aims of this study were to characterize the group of patients with BSOT and evaluate the significance of various molecular markers expression versus serous papillary ovarian carcinomas (SPOC) Material and methods We analyzed a total of 102 cases including: 64 cystadenoma, 10 borderline and 28 cystadenocarcinoma. doi = 10.1007/s00428-003-0864-5 id = cord-014996-p6q0f37c author = nan title = Posters_Monday_12 October 2009 date = 2009-08-06 keywords = AKI; ALI; APACHE; Care; Hospital; ICU; LPS; PCT; SAPS; VAP; conclusion; group; introduction; method; mortality; objectives; patient; result; sepsis; sofa; study summary = Data recorded on admission were the patient demographics with, acute physiology and chronic health evaluation II score (APACHE II), and type of admission; during intensive care stay, sepsis-related organ failure assessment score (SOFA) and clinical concomitant factors and conditions. For each severe septic patient the following data was registered: time delay, APACHE II and SOFA scores at ICU admission, diagnosis, the rate of compliance with the resucitation and management bundles, microbiological data, evolution of levels of serum lactate, empiric antibiotic therapy, length of stay and mortality in ICU. Sepsis and septic shock remain the most important causes of acute kidney injury (AKI) in critically ill patients and account for more than 50% of cases of acute renal failure (ARF) in intensive care units (ICU). There were no significant differences between the demographic data (sex, age) or the data on admission to intensive care (APACHE II score, ratio of medical to surgical patients) and duration of mechanical ventilation between the two groups. doi = 10.1007/s00134-009-1593-2 id = cord-015024-2xzc0uc5 author = nan title = ESICM 2010 WEDNESDAY SESSIONS 13 October 2010 date = 2010-08-31 keywords = APACHE; ARDS; CVP; Care; ECMO; Hospital; ICU; Intensive; conclusion; day; group; high; increase; introduction; level; method; objectives; patient; result; sepsis; sofa; study summary = We performed a prospective clinical study in a 17-bed multidisciplinary intensive care unit, including 21 patients with controlled mechanical ventilation and monitored with the Vigileo Ò monitor, for whom the decision to give fluids was taken due to the presence of circulatory, including arterial hypotension (MAP B 65 mmHg or systolic arterial pressure \90 mmHg), and preserved preload-responsiveness condition, defined as SVV C10%. The aim of this study was to compare and evaluate four severity scoring systems in intensive care unit (ICU), including APACHE II, APACHE III, SASP II and MODS in severe septic patient. A prospective observational study was performed in 16 mechanically ventilated critically ill patients (12 M, age 49 ± 17 yr, BMI 25 ± 5 kg/m 2 , ICU admission day 5 ± 3, APACHE II on study 20 ± 7; mean ± SD) and 6 healthy subjects (3 M, age 24 ± 9 year, BMI 24 ± 45 kg/m 2 ). doi = 10.1007/s00134-010-2001-7 id = cord-015090-n6f4xupw author = nan title = PS 339-563 date = 2005-09-10 keywords = Care; Hospital; ICP; ICU; Intensive; PCT; University; conclusion; day; level; method; patient; study summary = We designed this study to examine the effects of fiberoptic bronchoscopy (FOB) with and without BAL on body temperature, systemic arterial pressure, heart rate and supportive therapies requirements in mechanically ventilated patients. Clinical characteristics (Glasgow scale, heart rate, systolic blood pressure), cardiac enzymes (troponin I, total serum creatine kinase and myocardial isoenzyme, myoglobin), ECG changes (ST-T changes, prolonged QT and corrected QT intervals), echocardiographic assessment of cardiac function (left ventricular ejection fraction, hypokinesia) were studied on the day of the admission. It is a prospective study performed during 12 months of the patients with brain trauma admitted in a 24-beds medical-surgical ICU of a 650-beds university hospital. This prospective observational study included 200 adult patients admitted to a 31-bed university hospital medical-surgical ICU during a 3-month period. doi = 10.1007/s00134-005-2780-4 id = cord-015126-cyhcbk1j author = nan title = PS 0036-0344 date = 2007-08-25 keywords = APACHE; ARDS; Care; HFOV; Hospital; ICU; Intensive; PCT; VAP; blood; conclusion; day; group; increase; introduction; method; mortality; patient; peep; pressure; result; sofa; study summary = We compared them with ≥70 years old and an ICU stay < 30 days patients, the differences in ICU mortality, Apache II, age, gender and the necessity for renal replacement therapy (RRT) were not significant (see table) . The patients with mild form of acute pancreatitis had low mortality rate (similar to general ward population) despite positive ICU admission criteria in our case series with fifty per cent development of severe form with organ dysfunction/failure later on. Collected data:Demographics,Management prior and during ICU hospitalization (sedation, catecolamin drug use, blood product transfusion, intra-cranial pressure monitoring, neurosurgical emergency surgery etc.),CT-Scan results, Daily worst Glasgow coma scale, admission Simplified Acute Physiology Score II. This prospective interventional study performed in a surgical Intensive Care Unit of a tertiary University Hospital included 35 (21 males) mechanically ventilated and sedated patients with acute cardiovascular failure requiring cardiac output measurement (transpulmonary thermodilution technique)and a fluid challenge. doi = 10.1007/s00134-007-0820-y id = cord-015306-us58wwmp author = nan title = Abstracts for the IPNA Congress, 30 August - 3 September 2013, Shanghai, China date = 2013-06-21 keywords = AKI; CKD; DMSA; EBV; ESRD; HSP; HSPN; Hospital; NGAL; Nephrology; Objective; RSV; UTI; University; VUR; child; conclusion; group; kidney; level; method; patient; renal; result; study; year summary = The incidence of renal involvement varies from 20 to 60% and there have been some reports showing that nephritis might be related to an older age at onset, persistent purpura (> 1 month), severe abdominal pain, and relapsing disease.Recently, several studies have shown that galactose-deficient IgA1 (Gd-IgA1) is recognized by anti-glycan antibodies, resulting in the formation of the circulating immune complexes and their mesangial deposition causing renal injury in HSP nephritis and serum galactose-deficient IgA1 levels were highly inherited in children with HSP nephritis.Regarding the treatment of HSP, one randomized double-blinded controlled study recently showed that patients with abdiminal pain or arthralgia may benefit from early treatment with prednisone, but the drug has not been proven to be capable of preventing the development of renal symptoms. doi = 10.1007/s00467-013-2518-4 id = cord-015324-y44sfr0c author = nan title = Scientific Programme date = 2007-09-01 keywords = BMI; CKD; CRF; CRP; Children; DMSA; Department; ESRD; FSGS; GFR; Group; HIV; HSP; HUS; Hospital; III; MMF; Nephrology; PCR; PTH; Pediatric; SDS; SLE; SRNS; TGF; UTI; University; VUR; age; child; conclusion; disease; kidney; method; patient; renal; result; study; year summary = In order to further validate this approach, we performed a prospective randomized open-label multicenter trial in 41 low-risk pediatric renal transplant recipients (12 f, 29 m; mean age 10.1 yrs; range, 3.4 to 17.8) on CsA (target trough level 100-200 ng/ml), MMF (1200 mg/m 2 per day) and methylprednisolone (3) (4) mg/m 2 per day), who were randomly assigned >1 year posttransplant to continue steroids or to withdraw over a period of 3 months. We evaluated MMF in 15 children with LN, 11 F/4 M, mean age: 12.4±3.9 yrs, proteinuria >3 g/day, decreased C3 and increased anti-dsDNA serum levels, normal renal function. Patients and methods: 91 children and adolescents (60 male, 31 female, mean age at transplantation 9.7±5.2 years) with stable renal function and observation period exceeding 6 months were included. doi = 10.1007/s00467-007-0558-3 id = cord-015334-8p124rwp author = nan title = ESCP 36th European Symposium on Clinical Pharmacy ‘Implementing Clinical Pharmacy in Community and Hospital Settings: Sharing the Experience’, Istanbul, Turkey 25–27 October 2007; Abstracts date = 2008-06-11 keywords = Background; DRP; France; Hospital; Objective; Pharmacy; University; care; clinical; conclusion; drug; main; measure; outcome; patient; pharmacist; prescription; result; study; treatment summary = Based on the results of the pharmacoeconomic analysis, development of clinical pharmacy and CIVAS for some drugs will be discussed with the paediatric department Background and Objective: Studies show that up to 38% of patients starting treatment with antidepressants fill only a single prescription at the pharmacy, apparently not accepting treatment. Main Outcome Measures: Data collected were: nurses'' profile (age, length of service, competencies'' self-assessment), knowledge on drugs prescribed to their patients (usage, administration, side-effects, drug interactions…), use of existing tools (i.e. drugs database) and possible tools to be developed by the pharmacy ward to help them in their daily practice. The objectives were:(1)To identify the most relevant minor ailments, agreeing on the specific criteria for referral to the GP.(2)To select the non-prescription drugs, with evidence of safety and effectiveness, for the treatment of the identified minor ailments Design: Qualitative study with an expert panel which was made up of 2 primary care physician from SEMFYC and six community pharmacists (two members of SEFAC and four members of GIAF-UGR). doi = 10.1007/s11096-008-9226-3 id = cord-015348-qt0worsl author = nan title = Abstract date = 2010-07-30 keywords = Dept; EGFR; Hospital; IHC; MGMT; Objective; PCR; Pathology; University; VEGF; cancer; carcinoma; case; cell; conclusion; diagnosis; disease; dna; expression; kit; lesion; method; patient; result; study; tissue; tumor summary = However, the application of the compounds in clinical trials has revealed promising results only when predictive procedures have been available for determining which patients will benefit from targeting therapy, so-called eligibility or predictive tests, e.g. Her2 in breast cancer, KRAS and EGFR mutations in colorectal cancer and non-small cell lung cancer. Conclusion: We report on the development of a quantitative tissue-based immunohistochemical (IHC) methodology employing activation-specific antibodies against multiple components of the BCR signaling pathway that will assess the activity of the BCR pathway in formalin-fixed paraffinembedded primary DLBCLs. This approach will identify the subset of patient tumors that are actively signaling through the BCR pathway and, therefore, will predict therapeutic responsiveness to targeted inhibition of BCR signaling. Method: In our study, we investigate 120 cases diagnosed with invasive breast carcinoma in which we established microscopic characterization, immunohistochemical profiles (expression of proliferation markers, steroid receptors and Her2) and computer-assisted morphometric profiles by determining the mean values for nuclear area, cellular area and N/C ratio with Lucia Net Software. doi = 10.1007/s00428-010-0947-z id = cord-015354-yknwveyz author = nan title = Abstracts_Poster presentations date = 2007-09-18 keywords = 18F; CAD; DMSA; DOTA; DTPA; FBP; FDG; GFR; Group; HMPAO; Hospital; LVEF; MIBG; MIBI; MPS; MRI; Medicine; Nuclear; PET; ROI; SLN; SPECT; SUV; Siemens; Tc-99; University; WBS; aim; conclusion; high; i-123; i-131; image; mean; method; patient; result; scan; study; uptake summary = Material and Methods: Fourteen individuals (mean age 47±19y range 21-75y; 4W, 10M; including 10 volunteers and 4 patients with angiographically proved CAD) underwent dynamic PET imaging studies (21 frames) at rest and during adenosine stress (0.14mg/kg/min for 6 min) after injection of 1100MBq of 82Rb (Discovery LS, GEMS). Methods:Twenty-nine patients (21 males,8 females;62±11 yrs) with recent AMI were studied.Within 6 days after AMI, the patients were performed Tl-201 R-RD perfusion SPECT using 4 mCi activity.CMR was carried out 5-20 minutes after 0,15 mmol/kg of iv.Gadobutrol injection.Myocardial perfusion and contrast enhancement was analyzed using a 17 segment model.Myocardial perfusion was scored in Tl-201 SPECT as follows:0=normal (70%-100% maximal myocardial activity(mma), 1= 69-50% mma, 2= 49-30% mma ,3=29-10% mma and 4=<10% mma ;Myocardial contrast enhancement on CMR images was graded as:0=no contrast enhancement, 1=hyperenhancement of 0-25% of the wall thickness(WT) 2=hyperenhancement of 26-50 % of the WT, 3=hyperenhancement of 51-75 % of WT and 4=hyperenhancement of 76-100 % of WT.In CMR the existence of microvascular obstruction(MO) was also evaluated.Total segment scores(TSS) in R,RD and CMR for each patient were calculated by summing of 17 segment score values. doi = 10.1007/s00259-007-0544-9 id = cord-015394-uj7fe5y6 author = nan title = Scientific Abstracts date = 2008-12-23 keywords = ACTH; AEA; ANOVA; BMI; CRF; Center; ELISA; EOC; ERK; GDM; Gynecology; Hospital; IL-1; IL-6; IL-8; IUGR; IVF; LPS; Medical; Medicine; NIH; Netherlands; Obstetrics; P<0.05; PCOS; PCR; PPROM; RNA; Research; School; TNF; USA; University; VEGF; cell; conclusion; control; dna; expression; fetal; fsh; human; increase; level; maternal; method; objective; placental; pregnancy; result; study; western; woman summary = Studies involving immunohistochemical analysis of normal ovaries have shown that granulosa cells express significantly higher levels of the activator protein-1 (AP-1) transcription factor, cFos compared to theca cells, where cFos expression is virtually absent. Following acute hypoxia (0.5% O2) for one to six hours, RhoA mRNA, total protein and activation (RhoA-GTP) levels were analysed, using semi-quantitative PCRs and western blot, and compared to normoxic non-pregnant human uterine smooth muscle control cells. Since there is an urgent need for non-invasive methods for determination of fetal (F) and placental (P) function, this study was designed to evaluate the genes differently and commonly expressed in P tissue and leukocytes in maternal (M) and F circulation.Material and Methods. The current study: 1) localized IL-6 mRNA levels in preeclamptic versus normal decidual sections; 2) evaluated mechanisms regulating IL-6 synthesis by targeting intracellular signaling pathways with specific inhibitors; 3) identified potential IL-6 targets by immunolocalizing the IL-6 receptor (IL-6R) to specific cell types in placental bed biopsies. doi = 10.1177/19337191080150020102 id = cord-022633-fr55uod6 author = nan title = SAEM Abstracts, Plenary Session date = 2012-04-26 keywords = ACS; AED; Background; COPD; CPR; EMS; ETCO; Emergency; HIV; Hospital; ICU; IQR; LOS; MDD; OHCA; TBI; University; conclusion; datum; group; level; method; objective; patient; rate; result; study; time summary = Staff satisfaction was evaluated through pre/ post-shift and study surveys; administrative data (physician initial assessment (PIA), length of stay (LOS), patients leaving without being seen (LWBS) and against medical advice [LAMA] ) were collected from an electronic, real-time ED information system. Communication Background: The link between extended shift lengths, sleepiness, and occupational injury or illness has been shown, in other health care populations, to be an important and preventable public health concern but heretofore has not been fully described in emergency medical services (EMS Objectives: To assess the effect of an ED-based computer screening and referral intervention for IPV victims and to determine what characteristics resulted in a positive change in their safety. Objectives: Using data from longitudinal surveys by the American Board of Emergency Medicine, the primary objective of this study was to evaluate if resident self-assessments of performance in required competencies improve over the course of graduate medical training and in the years following. doi = 10.1111/j.1553-2712.2012.01332.x id = cord-022650-phsr10jp author = nan title = Abstracts TPS date = 2018-08-14 keywords = AIT; Ara; Background; Der; ELISA; FEV1; HAE; HDM; Hospital; IgE; LTP; PR-10; SCIT; SDS; SLIT; SPT; allergen; allergic; allergy; asthma; case; conclusion; food; group; high; level; method; patient; result; specific; study; symptom; test; treatment; year summary = 0685 | Skin prick test reactivity to aeroallergens in adult allergy clinic in a tertiary hospital: a 12-year retrospective study Results: Five different human sera were screened for specific IgE level against 29 different allergen sources using test methods of three different suppliers. Conclusion: This multicenter prospective study confirmed that stepwise single-dose OFC to egg will help to clarify the severity of egg allergy, and will contribute to improved food allergy manageMethod: The study design was a retrospective cohort study extracting data from the electronic chart of children older than 4 years who visited our out-patient clinic for egg or milk allergy and who underwent an oral food challenge test (OFC) twice within 24 months between November 2013 and December 2017. Results: In the base case analysis, using Italy clinical practice patients with moderate-to severe allergic rhino-conjunctivitis (SS ranging from 6 to 15 points) and a mean age at entry of 21 years, both SCIT and SLIT were associated with increased cost but superior efficacy compared to pharmacotherapy alone. doi = 10.1111/all.13539 id = cord-023049-fio7cjj5 author = nan title = 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain date = 2017-06-22 keywords = AMAN; Barré; CIDP; CMT; CSA; Center; Charcot; DRG; Department; EMG; FAP; France; GBS; GM1; Guillain; Hospital; IENFD; IVIG; Institute; Italy; Japan; MMN; MRC; MRI; Marie; Medical; Medicine; NCS; National; Neurology; Neuropathy; PMP22; PNS; School; Schwann; Singapore; TTR; Tooth; USA; University; cmt1a; mag; nerve; patient; study summary = Clinical efficacy (Medical Research Council sum score, 10-m walk, modified Inflammatory Neuropathy Cause and Treatment score, Overall Neuropathy Limitations Scale, Romberg test) and patient-reported outcomes (36-item Short Form Health Survey , Life Quality Index [LQI] ) were assessed at baseline and at regular intervals until the final visit (10-14 months after switching). To explore the issue of early biomarkers in FAP, we performed skin biopsy and compared IENF density with parameters of nerve conduction studies (NCS) and quantitative sensory testing (QST) on 36 subjects (23 men, aged 55.1 ± 11.1 years) with genetic confirmation of TTR-A97S: 17 patients and 19 carriers. Results: The Gly112Ser mutation causing CMT1C is a mild form of CMT, as patients walked on time, had less weakness than those with Charcot-Marie-Tooth Disease type 1A (CMT1A), had a Charcot Marie Tooth neuropathy score (CMTNS) indicative of mild disease, and had faster ulnar and median motor nerve conduction velocities compared to those with CMT1A. doi = 10.1111/jns.12225 id = cord-023157-0lqlx2rv author = nan title = Poster Sessions date = 2013-04-18 keywords = BMI; CAD; CRP; CVD; GDM; HDL; HFD; HOMA; Hospital; IFG; IGT; IL-6; NAFLD; OGTT; PCOS; T2DM; University; diabetes; glucose; group; high; insulin; level; metabolic; patient; result; study summary = The patients revealed the increase of free fatty acids level (2.19 AE 0.10) mmol/l/ml, that meaningfully differed from such indexes in the control group (P < 0.001) and low level of adiponektin (3.70 AE 0.70) mg/ml that confirms their role in development of NAFLD even for persons with normal body weight after the presence of abdominal type of adipose tissue distribution. Results: This study has shown effectiveness in reduction in fasting blood glucose (P < 0.01), systolic blood pressure (P = 0.03), diastolic blood pressure (P = 0.01), weight (P = 0.03), added sugar (P = 0.03) and fat consumption (P < 0.01) while improving physical activity (P < 0.01) and insulin sensitivity (P < 0.01) in the intervention group when compared with the control group at follow up assessment. Conclusion: Our study shows that infiltration of macrophages in human adipose tissue, estimated by the expression of macrophage markers, is increased in subjects with obesity and diabetes and associated with insulin sensitivity and serum lipid levels independent of BMI. doi = 10.1111/1753-0407.12032_1 id = cord-023211-kt5gt26t author = nan title = Poster Session Abstracts date = 2007-08-29 keywords = ASL; ATP; BMI; CFF; CFQ; CFRD; CFTR; Center; Cystic; DHA; FEV1; FVC; Fibrosis; Foundation; GFP; HBE; Hospital; IL-8; Isc; MRSA; Medical; NBD1; NIH; PCR; PKA; Pseudomonas; USA; United; University; airway; cell; conclusion; dna; increase; lung; method; patient; result; study; ∆F508; ∆F508-CFTR summary = Previous studies performed using fluorescence halide efflux measurements and short-circuit current voltage clamp have shown that treatment with PPARγ (peroxisome proliferator activated receptor gamma) agonists, such as pioglitazone and FLL (FMOC-L-leucine), resulted in an increased biosynthesis and trafficking of ∆F508-CFTR to the cell surface. Physiology, School of Medical Sciences, University of Bristol, Bristol, United Kingdom Recent progress in the development of small molecule correctors and potentiators capable of restoring CFTR function have increased the need for pre-clinical test models including cultured airway epithelial cells from human CF patients as well as CF mouse models. Clinical studies have linked increased sputum and peripheral blood neutrophil MPO activity with increased airflow obstruction in cystic fibrosis (CF) patients of the same age, gender, airway bacterial flora, and CFTR genotype. Because patients expressing low levels of normal CFTR mRNA (5-20%) have mild disease symptoms, these studies demonstrate that the incorporation of the ciliated cell-specific FOXJ1 promoter into gene therapy vectors may be useful for treatment of CF. doi = 10.1002/ppul.20700 id = cord-023346-8sqbqjm1 author = nan title = MONDAY: POSTERS date = 2005-06-08 keywords = ABO; DAT; FFP; HBV; HCV; HIV; HLA; Hospital; NAT; PCR; RBC; RHD; RNA; TRALI; Transfusion; anti; antibody; blood; cell; dna; donor; group; method; patient; platelet; result; study; system; test summary = • enhancement of automation/computerisation; • process control to provide an ''error-free pathway''; • (national) surveillance and trend analysis of results, preferably based on national working standards; • significantly increased sensitivity, especially from development of antigen/antibody ''combi'' assays (e.g. for HIV, and recently, for HCV); • awareness of HBsAg vaccine-escape mutants and design of assays to cope with this; • extension of range of agents and markers tested for (varies in different countries); • increasing range of assays available for testing donors with a relevant history of exposure to malaria or Chagas'' disease infection (for retrieval of otherwise wasted blood); • European Union''s in vitro diagnostics directive: this has caused some problems and reduced flexibility. doi = 10.1111/j.1423-0410.2005.00652.x id = cord-023354-f2ciho6o author = nan title = TUESDAY PLENARY SESSION 3 TUESDAY: POSTERS date = 2005-06-08 keywords = ABO; DAT; FFP; HBV; HCV; HIV; HLA; Hospital; NAT; PCR; RBC; RHD; RNA; TRALI; Transfusion; anti; antibody; blood; cell; dna; donor; group; method; patient; platelet; result; study; system; test summary = • enhancement of automation/computerisation; • process control to provide an ''error-free pathway''; • (national) surveillance and trend analysis of results, preferably based on national working standards; • significantly increased sensitivity, especially from development of antigen/antibody ''combi'' assays (e.g. for HIV, and recently, for HCV); • awareness of HBsAg vaccine-escape mutants and design of assays to cope with this; • extension of range of agents and markers tested for (varies in different countries); • increasing range of assays available for testing donors with a relevant history of exposure to malaria or Chagas'' disease infection (for retrieval of otherwise wasted blood); • European Union''s in vitro diagnostics directive: this has caused some problems and reduced flexibility. doi = 10.1111/j.1423-0410.2005.00654.x id = cord-023364-ut56gczm author = nan title = EDUCATION DAY MONDAY: PLENARY SESSION 1 MONDAY: PARALLEL SESSIONS date = 2005-06-08 keywords = ABO; DAT; FFP; HBV; HCV; HIV; HLA; Hospital; NAT; PCR; RBC; RHD; RNA; TRALI; Transfusion; anti; antibody; blood; cell; dna; donor; group; method; patient; platelet; result; study; system; test summary = • enhancement of automation/computerisation; • process control to provide an ''error-free pathway''; • (national) surveillance and trend analysis of results, preferably based on national working standards; • significantly increased sensitivity, especially from development of antigen/antibody ''combi'' assays (e.g. for HIV, and recently, for HCV); • awareness of HBsAg vaccine-escape mutants and design of assays to cope with this; • extension of range of agents and markers tested for (varies in different countries); • increasing range of assays available for testing donors with a relevant history of exposure to malaria or Chagas'' disease infection (for retrieval of otherwise wasted blood); • European Union''s in vitro diagnostics directive: this has caused some problems and reduced flexibility. doi = 10.1111/j.1423-0410.2005.00651.x id = cord-024651-578c9ut5 author = nan title = 2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference date = 2020-05-11 keywords = ALPS; Abstract; Background; CD4; CD8; CGD; CVID; Case; EBV; GOF; HIES; HLH; HSCT; Hospital; IFN; IVIG; Immunology; National; PID; Report; SCID; STAT3; Text; cell; disease; figure; infection; introduction; mutation; patient; result summary = Abstract/Case Report Text Introduction: Mutations in the gene encoding signal transducer and activator of transcription 3 (STAT3) cause autosomal dominant hyperimmunoglobulin E syndrome (AD-HIES) characterized by recurrent skin and sinopulmonary infections, atopic dermatitis, and elevated serum immunoglobulin E (IgE) levels. Objective: The purpose of this study is to increase awareness and improve diagnosis of primary immune deficiency (PID) in the heterogenous group of patients with autoimmune cytopenia (AIC) by identifying clinical characteristics and laboratory biomarkers that distinguish those with underlying PID, disease activity and guide mechanism-based targeted therapy. 7 Chief, Laboratory of Clinical Immunology and Microbiology/National Institute of Allergy and Infectious Diseases, NIAID/National Institutes of Health, NIH Abstract/Case Report Text We have previously used the artificial thymic organoid (ATO) system, based on the 3D aggregation and culture of a delta-like canonical Notch ligand 4-expressing stromal cell line (MS5-Dll4) with CD34+ cells, to study T cell differentiation from CD34+ cells obtained from patients carrying defects that are intrinsic to hematopoietic cells (RAG1-2, AK2, IL2RG) or that affect thymus development (DiGeorge syndrome). doi = 10.1007/s10875-020-00764-z id = cord-341063-3rqnu5bu author = nan title = 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date = 2018-03-29 keywords = AKI; APACHE; ARDS; Care; Critical; Fig; Hospital; ICU; IQR; IVC; Intensive; LOS; TBI; University; VAP; conclusion; day; group; high; introduction; method; mortality; patient; peep; result; score; sofa; study; table summary = Procacitonin (PCT) emerges as a possible predictive tool in cardiothoracic intensive care unit (CTICU).We aim at testing the predictive power of PCT for early morbidity, prolonged ventilation, ICU and hospital stay, in patients developing early fever after cardiac surgery Methods: A retrospective descriptive study done in tertiary cardiac center, enrolling patients who stayed for more than 24 hours post-operatively in the CTICU Risk stratification included additive Euro score and PCT immunoluminometricaly prior to surgery and every 48 hours in response to onset of fever. Prognostic accuracy of quick sequential organ failure assessment (qSOFA) score for mortality: systematic review and meta-analysis Introduction: The purpose of this study was to summarize the evidence assessing the qSOFA [1] , calculated in admission of the patient in emergency department (ED) or intensive care unit (ICU), as a predictor of mortality. doi = 10.1186/s13054-018-1973-5 id = cord-350571-6tapkjb6 author = nan title = 45th ESCP-NSF international symposium on clinical pharmacy: clinical pharmacy tackling inequalities and access to health care. Oslo, Norway, 5–7 October 2016 date = 2017-01-10 keywords = BZD; DRP; France; HCV; HIV; Hospital; January; June; Pharmacy; University; abstract; background; clinical; conclusion; descriptive; drug; medication; medicine; objective; patient; pharmacist; prescription; research; result; study; treatment; type summary = Possible solutions might be to use shared communication tools like Internet based communication programs and to introduce the patient as a participant at the IMRs. Please specify your abstract type: Research abstract Background and objective: International good pharmacy practice guidelines describe how pharmacists should counsel the patients about their medicines, offer additional services where needed, and intervene at drug related problems. Please specify your abstract type: Descriptive abstract (for projects) Background and objective: In order to improve the medication reconciliation and to implement training programs for the medical team in an associated to general hospital nursing (ASNH) home we measured the discrepancies between pharmacy registered treatments (PRT) and medical prescriptions (MP), and we analysed potentially inappropriate prescriptions according to ''''American Geriatrics Society 2015 Beers Criteria'''' and ''''STOPP-START 2014 criteria. doi = 10.1007/s11096-016-0404-4 id = cord-355038-o2hr5mox author = nan title = Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date = 2020-02-11 keywords = AKI; ARDS; CHU; COPD; Care; Correspondence; December; ECMO; Fig; France; Hospital; ICU; IQR; January; NIV; PICU; VAP; day; french; group; high; invitation; method; mortality; patient; rationale; result; sofa; study summary = Conclusion: In patients with moderate-to-severe ARDS, a higher tidal volume under PSV within the 72 h following neuromuscular blockers cessation is independently associated with the 28-day mortality.Compliance with ethics regulations: Yes. Kaplan-Meier estimate of the cumulative probability of survival according to the mean tidal volume (Vt)-lower of higher than 8 ml/ kg-under pressure support ventilation (PSV) during the "transition period" transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical setting. Compliance with ethics regulations: Yes. Patients and methods: In a retrospective monocentric study (01/2013-01/2017) conducted in cardio-vascular surgical intensive care unit (ICU) in Henri Mondor teaching hospital, all consecutive adult patients who underwent peripheral VA-ECMO were included, with exclusion of those dying in the first 24 h. Compliance with ethics regulations: Yes. Rationale: Acute respiratory failure is the leading reason for intensive care unit (ICU) admission in immunocompromised patients and the need for invasive mechanical ventilation has become a major clinical end-point in randomized controlled trials (RCT). doi = 10.1186/s13613-020-0623-7