id author title date pages extension mime words sentences flesch summary cache txt cord-291272-srt08jh8 Peters, E.J.G. Outcomes of persons with COVID-19 in hospitals with and without standard treatment with (Hydroxy)chloroquine 2020-10-14 .txt text/plain 2318 125 51 When stratified by actually received treatment in individual subjects, the use of (hydroxy)chloroquine was associated with an increased 21-day mortality (HR 1.58; 95%CI 1.24-2.02) in the full model. CONCLUSIONS: After adjustment for confounders, mortality was not significantly different in hospitals that routinely treated patients with (hydroxy)chloroquine, compared with hospitals that did not. The objective of this 142 study was to compare the effect of hospital-wide COVID-19 treatment strategies with or without 143 routine (H)CQ use on all-cause 21-day mortality. We performed a survival analysis using 177 log-rank test and Cox-regression with adjustment for age, sex, time in the pandemic (i.e., the number 178 of elapsed days after March 1 st 2020 at hospital admission),and covariates based on premorbid 179 health (i.e., history of lung, kidney and cardiovascular disease, diabetes mellitus, obesity, and 180 neoplasms or hematologic disease), disease severity during presentation (respiratory rate, oxygen 181 saturation) and the use of steroids, including dexamethasone, for adult respiratory distress 182 syndrome (ARDS) 12,13 . ./cache/cord-291272-srt08jh8.txt ./txt/cord-291272-srt08jh8.txt