id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007719-3ypv9k9p	Wang, Mingjun	Classification of Human Leukocyte Antigen (HLA) Supertypes	2014-05-06		.txt	text/plain	3649	158	51	Identification of new antigenic peptides, derived from infectious agents or cancer cells, which bind to human leukocyte antigen (HLA) class I and II molecules, is of importance for the development of new effective vaccines capable of activating the cellular arm of the immune response. Thus, identifi cation of new antigenic peptides, derived from infectious agents or tumor antigens, which may bind to HLA-I or HLA-II molecules in exchange with self-peptides normally occupying the HLA-binding site ( see below), is important for developing new effective vaccines capable of activating the cellular arm of the immune responses. To reduce this complexity, one option is to group thousands of different HLA molecules into clusters of several so-called HLA supertypes: a classifi cation that refers to a group of HLA alleles with largely overlapping peptide binding specifi cities.	./cache/cord-007719-3ypv9k9p.txt	./txt/cord-007719-3ypv9k9p.txt