id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004435-l66ost6q	Oli, Angus Nnamdi	Immunoinformatics and Vaccine Development: An Overview	2020-02-26		.txt	text/plain	8946	534	39	Even at the face of potential vaccine design advance, immune-related concerns (as seen with specific vulnerable populations, cases of emerging/re-emerging infectious disease, pathogens with complex lifecycle and antigenic variability, need for personalized vaccinations, and concerns for vaccines' immunological safety -specifically vaccine likelihood to trigger non-antigen-specific responses that may cause autoimmunity and vaccine allergy) are being raised. 13 An approach that must accommodate many factors affecting vaccine development like pathogen antigenic variability, the emergence of infectious disease, human genetic variation is the goal of immunoinformatics [ Figure 1 ]. 110 The surface glycoprotein can be regarded as antigen and hence can serve as a target for the immune system which if sequenced, using the new immunoinformatics approach and a common site for the varying proteins identified, a potent vaccine can be developed which can accommodate the antigenic drift/shifts of the virus.	./cache/cord-004435-l66ost6q.txt	./txt/cord-004435-l66ost6q.txt