id	sid	tid	token	lemma	pos
cord-264699-l8db5gll	1	1	key	key	NN
cord-264699-l8db5gll	1	2	:	:	:
cord-264699-l8db5gll	2	1	cord-264699-l8db5gll	cord-264699-l8db5gll	NNP
cord-264699-l8db5gll	2	2	authors	author	NNS
cord-264699-l8db5gll	2	3	:	:	:
cord-264699-l8db5gll	2	4	Kino	Kino	NNP
cord-264699-l8db5gll	2	5	,	,	,
cord-264699-l8db5gll	2	6	Tomoshige	Tomoshige	NNP
cord-264699-l8db5gll	2	7	;	;	:
cord-264699-l8db5gll	2	8	Chrousos	Chrousos	NNP
cord-264699-l8db5gll	2	9	,	,	,
cord-264699-l8db5gll	3	1	George	George	NNP
cord-264699-l8db5gll	3	2	P.	P.	NNP
cord-264699-l8db5gll	3	3	title	title	NN
cord-264699-l8db5gll	3	4	:	:	:
cord-264699-l8db5gll	4	1	Virus	virus	NN
cord-264699-l8db5gll	4	2	-	-	HYPH
cord-264699-l8db5gll	4	3	mediated	mediate	VBN
cord-264699-l8db5gll	4	4	modulation	modulation	NN
cord-264699-l8db5gll	4	5	of	of	IN
cord-264699-l8db5gll	4	6	the	the	DT
cord-264699-l8db5gll	4	7	host	host	NN
cord-264699-l8db5gll	4	8	endocrine	endocrine	JJ
cord-264699-l8db5gll	4	9	signaling	signal	VBG
cord-264699-l8db5gll	4	10	systems	system	NNS
cord-264699-l8db5gll	4	11	:	:	:
cord-264699-l8db5gll	4	12	clinical	clinical	JJ
cord-264699-l8db5gll	4	13	implications	implication	NNS
cord-264699-l8db5gll	4	14	date	date	NN
cord-264699-l8db5gll	4	15	:	:	:
cord-264699-l8db5gll	4	16	2007	2007	CD
cord-264699-l8db5gll	4	17	-	-	SYM
cord-264699-l8db5gll	4	18	06	06	CD
cord-264699-l8db5gll	4	19	-	-	SYM
cord-264699-l8db5gll	4	20	30	30	CD
cord-264699-l8db5gll	4	21	journal	journal	NN
cord-264699-l8db5gll	4	22	:	:	:
cord-264699-l8db5gll	4	23	Trends	Trends	NNPS
cord-264699-l8db5gll	4	24	in	in	IN
cord-264699-l8db5gll	4	25	Endocrinology	Endocrinology	NNP
cord-264699-l8db5gll	4	26	&	&	CC
cord-264699-l8db5gll	4	27	Metabolism	Metabolism	NNP
cord-264699-l8db5gll	4	28	DOI	DOI	NNP
cord-264699-l8db5gll	4	29	:	:	:
cord-264699-l8db5gll	4	30	10.1016/	10.1016/	CD
cord-264699-l8db5gll	5	1	j.tem.2007.03.003	j.tem.2007.03.003	NNP
cord-264699-l8db5gll	5	2	sha	sha	NNP
cord-264699-l8db5gll	5	3	:	:	:
cord-264699-l8db5gll	6	1	d7c7251214f9c61663727bd521da0ec96f66b11d	d7c7251214f9c61663727bd521da0ec96f66b11d	NNP
cord-264699-l8db5gll	7	1	doc_id	doc_id	CD
cord-264699-l8db5gll	8	1	:	:	:
cord-264699-l8db5gll	8	2	264699	264699	CD
cord-264699-l8db5gll	8	3	cord_uid	cord_uid	NNS
cord-264699-l8db5gll	8	4	:	:	:
cord-264699-l8db5gll	9	1	l8db5gll	l8db5gll	LS
cord-264699-l8db5gll	9	2	Viruses	virus	NNS
cord-264699-l8db5gll	9	3	,	,	,
cord-264699-l8db5gll	9	4	which	which	WDT
cord-264699-l8db5gll	9	5	are	be	VBP
cord-264699-l8db5gll	9	6	among	among	IN
cord-264699-l8db5gll	9	7	the	the	DT
cord-264699-l8db5gll	9	8	simplest	simple	JJS
cord-264699-l8db5gll	9	9	infective	infective	JJ
cord-264699-l8db5gll	9	10	pathogens	pathogen	NNS
cord-264699-l8db5gll	9	11	,	,	,
cord-264699-l8db5gll	9	12	can	can	MD
cord-264699-l8db5gll	9	13	produce	produce	VB
cord-264699-l8db5gll	9	14	characteristic	characteristic	JJ
cord-264699-l8db5gll	9	15	endocrine	endocrine	JJ
cord-264699-l8db5gll	9	16	manifestations	manifestation	NNS
cord-264699-l8db5gll	9	17	in	in	IN
cord-264699-l8db5gll	9	18	infected	infected	JJ
cord-264699-l8db5gll	9	19	patients	patient	NNS
cord-264699-l8db5gll	9	20	.	.	.
cord-264699-l8db5gll	10	1	In	in	IN
cord-264699-l8db5gll	10	2	addition	addition	NN
cord-264699-l8db5gll	10	3	to	to	IN
cord-264699-l8db5gll	10	4	the	the	DT
cord-264699-l8db5gll	10	5	classic	classic	JJ
cord-264699-l8db5gll	10	6	modification	modification	NN
cord-264699-l8db5gll	10	7	of	of	IN
cord-264699-l8db5gll	10	8	the	the	DT
cord-264699-l8db5gll	10	9	host	host	NN
cord-264699-l8db5gll	10	10	endocrine	endocrine	NN
cord-264699-l8db5gll	10	11	system	system	NN
cord-264699-l8db5gll	10	12	by	by	IN
cord-264699-l8db5gll	10	13	either	either	CC
cord-264699-l8db5gll	10	14	direct	direct	JJ
cord-264699-l8db5gll	10	15	or	or	CC
cord-264699-l8db5gll	10	16	indirect	indirect	JJ
cord-264699-l8db5gll	10	17	destruction	destruction	NN
cord-264699-l8db5gll	10	18	of	of	IN
cord-264699-l8db5gll	10	19	the	the	DT
cord-264699-l8db5gll	10	20	endocrine	endocrine	JJ
cord-264699-l8db5gll	10	21	organs	organ	NNS
cord-264699-l8db5gll	10	22	and/or	and/or	CC
cord-264699-l8db5gll	10	23	effects	effect	NNS
cord-264699-l8db5gll	10	24	exerted	exert	VBN
cord-264699-l8db5gll	10	25	by	by	IN
cord-264699-l8db5gll	10	26	systemic	systemic	JJ
cord-264699-l8db5gll	10	27	production	production	NN
cord-264699-l8db5gll	10	28	of	of	IN
cord-264699-l8db5gll	10	29	inflammatory	inflammatory	NN
cord-264699-l8db5gll	10	30	and/or	and/or	CC
cord-264699-l8db5gll	10	31	stress	stress	NN
cord-264699-l8db5gll	10	32	mediators	mediator	NNS
cord-264699-l8db5gll	10	33	,	,	,
cord-264699-l8db5gll	10	34	recent	recent	JJ
cord-264699-l8db5gll	10	35	progress	progress	NN
cord-264699-l8db5gll	10	36	in	in	IN
cord-264699-l8db5gll	10	37	molecular	molecular	JJ
cord-264699-l8db5gll	10	38	virology	virology	NN
cord-264699-l8db5gll	10	39	and	and	CC
cord-264699-l8db5gll	10	40	endocrinology	endocrinology	NN
cord-264699-l8db5gll	10	41	has	have	VBZ
cord-264699-l8db5gll	10	42	revealed	reveal	VBN
cord-264699-l8db5gll	10	43	that	that	IN
cord-264699-l8db5gll	10	44	virus	virus	NN
cord-264699-l8db5gll	10	45	-	-	HYPH
cord-264699-l8db5gll	10	46	encoded	encode	VBN
cord-264699-l8db5gll	10	47	molecules	molecule	NNS
cord-264699-l8db5gll	10	48	might	may	MD
cord-264699-l8db5gll	10	49	alter	alter	VB
cord-264699-l8db5gll	10	50	the	the	DT
cord-264699-l8db5gll	10	51	host	host	NN
cord-264699-l8db5gll	10	52	endocrine	endocrine	NN
cord-264699-l8db5gll	10	53	-	-	HYPH
cord-264699-l8db5gll	10	54	signaling	signal	VBG
cord-264699-l8db5gll	10	55	systems	system	NNS
cord-264699-l8db5gll	10	56	by	by	IN
cord-264699-l8db5gll	10	57	affecting	affect	VBG
cord-264699-l8db5gll	10	58	extracellular	extracellular	JJ
cord-264699-l8db5gll	10	59	and/or	and/or	CC
cord-264699-l8db5gll	10	60	intracellular	intracellular	JJ
cord-264699-l8db5gll	10	61	signal	signal	NN
cord-264699-l8db5gll	10	62	transduction	transduction	NN
cord-264699-l8db5gll	10	63	and	and	CC
cord-264699-l8db5gll	10	64	hormone	hormone	NN
cord-264699-l8db5gll	10	65	sensitivity	sensitivity	NN
cord-264699-l8db5gll	10	66	of	of	IN
cord-264699-l8db5gll	10	67	host	host	NN
cord-264699-l8db5gll	10	68	target	target	NN
cord-264699-l8db5gll	10	69	tissues	tissue	NNS
cord-264699-l8db5gll	10	70	.	.	.
cord-264699-l8db5gll	11	1	Here	here	RB
cord-264699-l8db5gll	11	2	,	,	,
cord-264699-l8db5gll	11	3	we	-PRON-	PRP
cord-264699-l8db5gll	11	4	provide	provide	VBP
cord-264699-l8db5gll	11	5	a	a	DT
cord-264699-l8db5gll	11	6	brief	brief	JJ
cord-264699-l8db5gll	11	7	overview	overview	NN
cord-264699-l8db5gll	11	8	of	of	IN
cord-264699-l8db5gll	11	9	such	such	JJ
cord-264699-l8db5gll	11	10	viral	viral	RB
cord-264699-l8db5gll	11	11	-	-	HYPH
cord-264699-l8db5gll	11	12	mediated	mediate	VBN
cord-264699-l8db5gll	11	13	modulation	modulation	NN
cord-264699-l8db5gll	11	14	of	of	IN
cord-264699-l8db5gll	11	15	host	host	NN
cord-264699-l8db5gll	11	16	endocrine	endocrine	JJ
cord-264699-l8db5gll	11	17	signaling	signal	VBG
cord-264699-l8db5gll	11	18	systems	system	NNS
cord-264699-l8db5gll	11	19	.	.	.
cord-264699-l8db5gll	12	1	We	-PRON-	PRP
cord-264699-l8db5gll	12	2	propose	propose	VBP
cord-264699-l8db5gll	12	3	that	that	IN
cord-264699-l8db5gll	12	4	virus	virus	NN
cord-264699-l8db5gll	12	5	-	-	HYPH
cord-264699-l8db5gll	12	6	encoded	encode	VBN
cord-264699-l8db5gll	12	7	molecules	molecule	NNS
cord-264699-l8db5gll	12	8	and	and	CC
cord-264699-l8db5gll	12	9	the	the	DT
cord-264699-l8db5gll	12	10	signaling	signal	VBG
cord-264699-l8db5gll	12	11	systems	system	NNS
cord-264699-l8db5gll	12	12	they	-PRON-	PRP
cord-264699-l8db5gll	12	13	influence	influence	VBP
cord-264699-l8db5gll	12	14	are	be	VBP
cord-264699-l8db5gll	12	15	potential	potential	JJ
cord-264699-l8db5gll	12	16	therapeutic	therapeutic	JJ
cord-264699-l8db5gll	12	17	targets	target	NNS
cord-264699-l8db5gll	12	18	for	for	IN
cord-264699-l8db5gll	12	19	the	the	DT
cord-264699-l8db5gll	12	20	treatment	treatment	NN
cord-264699-l8db5gll	12	21	of	of	IN
cord-264699-l8db5gll	12	22	disorders	disorder	NNS
cord-264699-l8db5gll	12	23	that	that	WDT
cord-264699-l8db5gll	12	24	are	be	VBP
cord-264699-l8db5gll	12	25	associated	associate	VBN
cord-264699-l8db5gll	12	26	with	with	IN
cord-264699-l8db5gll	12	27	some	some	DT
cord-264699-l8db5gll	12	28	viral	viral	JJ
cord-264699-l8db5gll	12	29	infections	infection	NNS
cord-264699-l8db5gll	12	30	.	.	.
cord-264699-l8db5gll	13	1	Viruses	virus	NNS
cord-264699-l8db5gll	13	2	are	be	VBP
cord-264699-l8db5gll	13	3	among	among	IN
cord-264699-l8db5gll	13	4	the	the	DT
cord-264699-l8db5gll	13	5	simplest	simple	JJS
cord-264699-l8db5gll	13	6	infective	infective	JJ
cord-264699-l8db5gll	13	7	pathogens	pathogen	NNS
cord-264699-l8db5gll	13	8	on	on	IN
cord-264699-l8db5gll	13	9	earth	earth	NN
cord-264699-l8db5gll	13	10	.	.	.
cord-264699-l8db5gll	14	1	Viruses	virus	NNS
cord-264699-l8db5gll	14	2	cause	cause	VBP
cord-264699-l8db5gll	14	3	a	a	DT
cord-264699-l8db5gll	14	4	variety	variety	NN
cord-264699-l8db5gll	14	5	of	of	IN
cord-264699-l8db5gll	14	6	pathological	pathological	JJ
cord-264699-l8db5gll	14	7	conditions	condition	NNS
cord-264699-l8db5gll	14	8	of	of	IN
cord-264699-l8db5gll	14	9	occasionally	occasionally	RB
cord-264699-l8db5gll	14	10	pandemic	pandemic	JJ
cord-264699-l8db5gll	14	11	proportions	proportion	NNS
cord-264699-l8db5gll	14	12	,	,	,
cord-264699-l8db5gll	14	13	and	and	CC
cord-264699-l8db5gll	14	14	constitute	constitute	VBP
cord-264699-l8db5gll	14	15	potential	potential	JJ
cord-264699-l8db5gll	14	16	major	major	JJ
cord-264699-l8db5gll	14	17	threats	threat	NNS
cord-264699-l8db5gll	14	18	to	to	IN
cord-264699-l8db5gll	14	19	the	the	DT
cord-264699-l8db5gll	14	20	human	human	JJ
cord-264699-l8db5gll	14	21	population	population	NN
cord-264699-l8db5gll	14	22	[	[	-LRB-
cord-264699-l8db5gll	14	23	1	1	CD
cord-264699-l8db5gll	14	24	]	]	-RRB-
cord-264699-l8db5gll	14	25	.	.	.
cord-264699-l8db5gll	15	1	Even	even	RB
cord-264699-l8db5gll	15	2	after	after	IN
cord-264699-l8db5gll	15	3	the	the	DT
cord-264699-l8db5gll	15	4	development	development	NN
cord-264699-l8db5gll	15	5	of	of	IN
cord-264699-l8db5gll	15	6	vaccines	vaccine	NNS
cord-264699-l8db5gll	15	7	,	,	,
cord-264699-l8db5gll	15	8	which	which	WDT
cord-264699-l8db5gll	15	9	have	have	VBP
cord-264699-l8db5gll	15	10	been	be	VBN
cord-264699-l8db5gll	15	11	tremendously	tremendously	RB
cord-264699-l8db5gll	15	12	effective	effective	JJ
cord-264699-l8db5gll	15	13	in	in	IN
cord-264699-l8db5gll	15	14	controlling	control	VBG
cord-264699-l8db5gll	15	15	many	many	JJ
cord-264699-l8db5gll	15	16	viral	viral	JJ
cord-264699-l8db5gll	15	17	infections	infection	NNS
cord-264699-l8db5gll	15	18	,	,	,
cord-264699-l8db5gll	15	19	viruses	virus	NNS
cord-264699-l8db5gll	15	20	are	be	VBP
cord-264699-l8db5gll	15	21	still	still	RB
cord-264699-l8db5gll	15	22	among	among	IN
cord-264699-l8db5gll	15	23	the	the	DT
cord-264699-l8db5gll	15	24	most	most	RBS
cord-264699-l8db5gll	15	25	common	common	JJ
cord-264699-l8db5gll	15	26	human	human	JJ
cord-264699-l8db5gll	15	27	pathogens	pathogen	NNS
cord-264699-l8db5gll	15	28	,	,	,
cord-264699-l8db5gll	15	29	sometimes	sometimes	RB
cord-264699-l8db5gll	15	30	causing	cause	VBG
cord-264699-l8db5gll	15	31	life	life	NN
cord-264699-l8db5gll	15	32	-	-	HYPH
cord-264699-l8db5gll	15	33	threatening	threaten	VBG
cord-264699-l8db5gll	15	34	diseases	disease	NNS
cord-264699-l8db5gll	15	35	[	[	-LRB-
cord-264699-l8db5gll	15	36	1	1	CD
cord-264699-l8db5gll	15	37	]	]	-RRB-
cord-264699-l8db5gll	15	38	.	.	.
cord-264699-l8db5gll	16	1	The	the	DT
cord-264699-l8db5gll	16	2	latter	latter	JJ
cord-264699-l8db5gll	16	3	is	be	VBZ
cord-264699-l8db5gll	16	4	evident	evident	JJ
cord-264699-l8db5gll	16	5	from	from	IN
cord-264699-l8db5gll	16	6	recent	recent	JJ
cord-264699-l8db5gll	16	7	epidemics	epidemic	NNS
cord-264699-l8db5gll	16	8	,	,	,
cord-264699-l8db5gll	16	9	such	such	JJ
cord-264699-l8db5gll	16	10	as	as	IN
cord-264699-l8db5gll	16	11	acquired	acquire	VBN
cord-264699-l8db5gll	16	12	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	16	13	syndrome	syndrome	NN
cord-264699-l8db5gll	16	14	(	(	-LRB-
cord-264699-l8db5gll	16	15	AIDS	AIDS	NNP
cord-264699-l8db5gll	16	16	)	)	-RRB-
cord-264699-l8db5gll	16	17	,	,	,
cord-264699-l8db5gll	16	18	caused	cause	VBN
cord-264699-l8db5gll	16	19	by	by	IN
cord-264699-l8db5gll	16	20	the	the	DT
cord-264699-l8db5gll	16	21	human	human	JJ
cord-264699-l8db5gll	16	22	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	16	23	virus	virus	NN
cord-264699-l8db5gll	16	24	type-1	type-1	NNP
cord-264699-l8db5gll	16	25	(	(	-LRB-
cord-264699-l8db5gll	16	26	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	16	27	)	)	-RRB-
cord-264699-l8db5gll	16	28	,	,	,
cord-264699-l8db5gll	16	29	and	and	CC
cord-264699-l8db5gll	16	30	severe	severe	JJ
cord-264699-l8db5gll	16	31	acute	acute	JJ
cord-264699-l8db5gll	16	32	respiratory	respiratory	JJ
cord-264699-l8db5gll	16	33	syndrome	syndrome	NN
cord-264699-l8db5gll	16	34	(	(	-LRB-
cord-264699-l8db5gll	16	35	SARS	SARS	NNP
cord-264699-l8db5gll	16	36	)	)	-RRB-
cord-264699-l8db5gll	16	37	,	,	,
cord-264699-l8db5gll	16	38	caused	cause	VBN
cord-264699-l8db5gll	16	39	by	by	IN
cord-264699-l8db5gll	16	40	the	the	DT
cord-264699-l8db5gll	16	41	SARS	SARS	NNP
cord-264699-l8db5gll	16	42	corona	corona	NNP
cord-264699-l8db5gll	16	43	virus	virus	NN
cord-264699-l8db5gll	16	44	[	[	-LRB-
cord-264699-l8db5gll	16	45	2	2	CD
cord-264699-l8db5gll	16	46	,	,	,
cord-264699-l8db5gll	16	47	3	3	CD
cord-264699-l8db5gll	16	48	]	]	-RRB-
cord-264699-l8db5gll	16	49	.	.	.
cord-264699-l8db5gll	17	1	Replication	replication	NN
cord-264699-l8db5gll	17	2	and	and	CC
cord-264699-l8db5gll	17	3	survival	survival	NN
cord-264699-l8db5gll	17	4	of	of	IN
cord-264699-l8db5gll	17	5	viruses	virus	NNS
cord-264699-l8db5gll	17	6	inside	inside	IN
cord-264699-l8db5gll	17	7	host	host	NN
cord-264699-l8db5gll	17	8	cells	cell	NNS
cord-264699-l8db5gll	17	9	are	be	VBP
cord-264699-l8db5gll	17	10	dependent	dependent	JJ
cord-264699-l8db5gll	17	11	on	on	IN
cord-264699-l8db5gll	17	12	the	the	DT
cord-264699-l8db5gll	17	13	cellular	cellular	JJ
cord-264699-l8db5gll	17	14	machinery	machinery	NN
cord-264699-l8db5gll	17	15	of	of	IN
cord-264699-l8db5gll	17	16	the	the	DT
cord-264699-l8db5gll	17	17	host	host	NN
cord-264699-l8db5gll	17	18	.	.	.
cord-264699-l8db5gll	18	1	Viruses	virus	NNS
cord-264699-l8db5gll	18	2	might	may	MD
cord-264699-l8db5gll	18	3	usurp	usurp	VB
cord-264699-l8db5gll	18	4	the	the	DT
cord-264699-l8db5gll	18	5	regulation	regulation	NN
cord-264699-l8db5gll	18	6	of	of	IN
cord-264699-l8db5gll	18	7	and	and	CC
cord-264699-l8db5gll	18	8	change	change	VB
cord-264699-l8db5gll	18	9	host	host	NN
cord-264699-l8db5gll	18	10	-	-	HYPH
cord-264699-l8db5gll	18	11	cell	cell	NN
cord-264699-l8db5gll	18	12	functions	function	NNS
cord-264699-l8db5gll	18	13	for	for	IN
cord-264699-l8db5gll	18	14	their	-PRON-	PRP$
cord-264699-l8db5gll	18	15	benefit	benefit	NN
cord-264699-l8db5gll	18	16	.	.	.
cord-264699-l8db5gll	19	1	Indeed	indeed	RB
cord-264699-l8db5gll	19	2	,	,	,
cord-264699-l8db5gll	19	3	through	through	IN
cord-264699-l8db5gll	19	4	molecules	molecule	NNS
cord-264699-l8db5gll	19	5	encoded	encode	VBN
cord-264699-l8db5gll	19	6	by	by	IN
cord-264699-l8db5gll	19	7	viral	viral	JJ
cord-264699-l8db5gll	19	8	genetic	genetic	JJ
cord-264699-l8db5gll	19	9	material	material	NN
cord-264699-l8db5gll	19	10	,	,	,
cord-264699-l8db5gll	19	11	whose	whose	WP$
cord-264699-l8db5gll	19	12	expression	expression	NN
cord-264699-l8db5gll	19	13	is	be	VBZ
cord-264699-l8db5gll	19	14	synchronized	synchronize	VBN
cord-264699-l8db5gll	19	15	with	with	IN
cord-264699-l8db5gll	19	16	specific	specific	JJ
cord-264699-l8db5gll	19	17	phases	phase	NNS
cord-264699-l8db5gll	19	18	of	of	IN
cord-264699-l8db5gll	19	19	the	the	DT
cord-264699-l8db5gll	19	20	viral	viral	JJ
cord-264699-l8db5gll	19	21	life	life	NN
cord-264699-l8db5gll	19	22	cycle	cycle	NN
cord-264699-l8db5gll	19	23	,	,	,
cord-264699-l8db5gll	19	24	viruses	virus	NNS
cord-264699-l8db5gll	19	25	increase	increase	VBP
cord-264699-l8db5gll	19	26	the	the	DT
cord-264699-l8db5gll	19	27	chance	chance	NN
cord-264699-l8db5gll	19	28	of	of	IN
cord-264699-l8db5gll	19	29	their	-PRON-	PRP$
cord-264699-l8db5gll	19	30	own	own	JJ
cord-264699-l8db5gll	19	31	replication	replication	NN
cord-264699-l8db5gll	19	32	and	and	CC
cord-264699-l8db5gll	19	33	survival	survival	NN
cord-264699-l8db5gll	19	34	.	.	.
cord-264699-l8db5gll	20	1	Virusinduced	virusinduced	JJ
cord-264699-l8db5gll	20	2	alterations	alteration	NNS
cord-264699-l8db5gll	20	3	of	of	IN
cord-264699-l8db5gll	20	4	host	host	NN
cord-264699-l8db5gll	20	5	-	-	HYPH
cord-264699-l8db5gll	20	6	cell	cell	NN
cord-264699-l8db5gll	20	7	functions	function	NNS
cord-264699-l8db5gll	20	8	cause	cause	VBP
cord-264699-l8db5gll	20	9	a	a	DT
cord-264699-l8db5gll	20	10	broad	broad	JJ
cord-264699-l8db5gll	20	11	spectrum	spectrum	NN
cord-264699-l8db5gll	20	12	of	of	IN
cord-264699-l8db5gll	20	13	cellular	cellular	JJ
cord-264699-l8db5gll	20	14	damage	damage	NN
cord-264699-l8db5gll	20	15	,	,	,
cord-264699-l8db5gll	20	16	from	from	IN
cord-264699-l8db5gll	20	17	a	a	DT
cord-264699-l8db5gll	20	18	transient	transient	JJ
cord-264699-l8db5gll	20	19	,	,	,
cord-264699-l8db5gll	20	20	mild	mild	JJ
cord-264699-l8db5gll	20	21	change	change	NN
cord-264699-l8db5gll	20	22	of	of	IN
cord-264699-l8db5gll	20	23	function	function	NN
cord-264699-l8db5gll	20	24	to	to	IN
cord-264699-l8db5gll	20	25	neoplastic	neoplastic	JJ
cord-264699-l8db5gll	20	26	transformation	transformation	NN
cord-264699-l8db5gll	20	27	,	,	,
cord-264699-l8db5gll	20	28	apoptosis	apoptosis	NN
cord-264699-l8db5gll	20	29	and	and	CC
cord-264699-l8db5gll	20	30	necrosis	necrosis	NN
cord-264699-l8db5gll	20	31	.	.	.
cord-264699-l8db5gll	21	1	Recent	recent	JJ
cord-264699-l8db5gll	21	2	research	research	NN
cord-264699-l8db5gll	21	3	has	have	VBZ
cord-264699-l8db5gll	21	4	revealed	reveal	VBN
cord-264699-l8db5gll	21	5	that	that	IN
cord-264699-l8db5gll	21	6	viruses	virus	NNS
cord-264699-l8db5gll	21	7	,	,	,
cord-264699-l8db5gll	21	8	through	through	IN
cord-264699-l8db5gll	21	9	the	the	DT
cord-264699-l8db5gll	21	10	molecules	molecule	NNS
cord-264699-l8db5gll	21	11	they	-PRON-	PRP
cord-264699-l8db5gll	21	12	encode	encode	VBP
cord-264699-l8db5gll	21	13	,	,	,
cord-264699-l8db5gll	21	14	modulate	modulate	VB
cord-264699-l8db5gll	21	15	endocrine	endocrine	JJ
cord-264699-l8db5gll	21	16	signaling	signal	VBG
cord-264699-l8db5gll	21	17	systems	system	NNS
cord-264699-l8db5gll	21	18	in	in	IN
cord-264699-l8db5gll	21	19	the	the	DT
cord-264699-l8db5gll	21	20	host	host	NN
cord-264699-l8db5gll	21	21	to	to	TO
cord-264699-l8db5gll	21	22	cause	cause	VB
cord-264699-l8db5gll	21	23	characteristic	characteristic	JJ
cord-264699-l8db5gll	21	24	changes	change	NNS
cord-264699-l8db5gll	21	25	in	in	IN
cord-264699-l8db5gll	21	26	both	both	DT
cord-264699-l8db5gll	21	27	endocrine	endocrine	JJ
cord-264699-l8db5gll	21	28	organs	organ	NNS
cord-264699-l8db5gll	21	29	and	and	CC
cord-264699-l8db5gll	21	30	hormone	hormone	NN
cord-264699-l8db5gll	21	31	target	target	NN
cord-264699-l8db5gll	21	32	tissues	tissue	NNS
cord-264699-l8db5gll	21	33	.	.	.
cord-264699-l8db5gll	22	1	Here	here	RB
cord-264699-l8db5gll	22	2	,	,	,
cord-264699-l8db5gll	22	3	we	-PRON-	PRP
cord-264699-l8db5gll	22	4	provide	provide	VBP
cord-264699-l8db5gll	22	5	a	a	DT
cord-264699-l8db5gll	22	6	brief	brief	JJ
cord-264699-l8db5gll	22	7	overview	overview	NN
cord-264699-l8db5gll	22	8	of	of	IN
cord-264699-l8db5gll	22	9	recent	recent	JJ
cord-264699-l8db5gll	22	10	progress	progress	NN
cord-264699-l8db5gll	22	11	in	in	IN
cord-264699-l8db5gll	22	12	understanding	understand	VBG
cord-264699-l8db5gll	22	13	virus	virus	NN
cord-264699-l8db5gll	22	14	-	-	HYPH
cord-264699-l8db5gll	22	15	induced	induce	VBN
cord-264699-l8db5gll	22	16	modifications	modification	NNS
cord-264699-l8db5gll	22	17	of	of	IN
cord-264699-l8db5gll	22	18	endocrine	endocrine	JJ
cord-264699-l8db5gll	22	19	signaling	signal	VBG
cord-264699-l8db5gll	22	20	systems	system	NNS
cord-264699-l8db5gll	22	21	and	and	CC
cord-264699-l8db5gll	22	22	of	of	IN
cord-264699-l8db5gll	22	23	the	the	DT
cord-264699-l8db5gll	22	24	resultant	resultant	JJ
cord-264699-l8db5gll	22	25	pathological	pathological	JJ
cord-264699-l8db5gll	22	26	states	state	NNS
cord-264699-l8db5gll	22	27	in	in	IN
cord-264699-l8db5gll	22	28	the	the	DT
cord-264699-l8db5gll	22	29	host	host	NN
cord-264699-l8db5gll	22	30	.	.	.
cord-264699-l8db5gll	23	1	On	on	IN
cord-264699-l8db5gll	23	2	the	the	DT
cord-264699-l8db5gll	23	3	basis	basis	NN
cord-264699-l8db5gll	23	4	of	of	IN
cord-264699-l8db5gll	23	5	this	this	DT
cord-264699-l8db5gll	23	6	understanding	understanding	NN
cord-264699-l8db5gll	23	7	,	,	,
cord-264699-l8db5gll	23	8	potential	potential	JJ
cord-264699-l8db5gll	23	9	new	new	JJ
cord-264699-l8db5gll	23	10	therapeutic	therapeutic	JJ
cord-264699-l8db5gll	23	11	targets	target	NNS
cord-264699-l8db5gll	23	12	for	for	IN
cord-264699-l8db5gll	23	13	the	the	DT
cord-264699-l8db5gll	23	14	development	development	NN
cord-264699-l8db5gll	23	15	of	of	IN
cord-264699-l8db5gll	23	16	anti	anti	JJ
cord-264699-l8db5gll	23	17	-	-	JJ
cord-264699-l8db5gll	23	18	viral	viral	JJ
cord-264699-l8db5gll	23	19	disease	disease	NN
cord-264699-l8db5gll	23	20	agents	agent	NNS
cord-264699-l8db5gll	23	21	are	be	VBP
cord-264699-l8db5gll	23	22	envisioned	envision	VBN
cord-264699-l8db5gll	23	23	.	.	.
cord-264699-l8db5gll	24	1	Virus	virus	NN
cord-264699-l8db5gll	24	2	-	-	HYPH
cord-264699-l8db5gll	24	3	induced	induce	VBN
cord-264699-l8db5gll	24	4	modifications	modification	NNS
cord-264699-l8db5gll	24	5	of	of	IN
cord-264699-l8db5gll	24	6	host	host	NN
cord-264699-l8db5gll	24	7	endocrine	endocrine	JJ
cord-264699-l8db5gll	24	8	systems	system	NNS
cord-264699-l8db5gll	24	9	:	:	:
cord-264699-l8db5gll	25	1	the	the	DT
cord-264699-l8db5gll	25	2	classic	classic	JJ
cord-264699-l8db5gll	25	3	view	view	NN
cord-264699-l8db5gll	25	4	Generally	generally	RB
cord-264699-l8db5gll	25	5	,	,	,
cord-264699-l8db5gll	25	6	entry	entry	NN
cord-264699-l8db5gll	25	7	of	of	IN
cord-264699-l8db5gll	25	8	viruses	virus	NNS
cord-264699-l8db5gll	25	9	into	into	IN
cord-264699-l8db5gll	25	10	and	and	CC
cord-264699-l8db5gll	25	11	infection	infection	NN
cord-264699-l8db5gll	25	12	of	of	IN
cord-264699-l8db5gll	25	13	host	host	NN
cord-264699-l8db5gll	25	14	tissues	tissue	NNS
cord-264699-l8db5gll	25	15	evokes	evoke	VBZ
cord-264699-l8db5gll	25	16	several	several	JJ
cord-264699-l8db5gll	25	17	levels	level	NNS
cord-264699-l8db5gll	25	18	of	of	IN
cord-264699-l8db5gll	25	19	host	host	NN
cord-264699-l8db5gll	25	20	reactions	reaction	NNS
cord-264699-l8db5gll	25	21	that	that	WDT
cord-264699-l8db5gll	25	22	might	may	MD
cord-264699-l8db5gll	25	23	be	be	VB
cord-264699-l8db5gll	25	24	associated	associate	VBN
cord-264699-l8db5gll	25	25	with	with	IN
cord-264699-l8db5gll	25	26	pathological	pathological	JJ
cord-264699-l8db5gll	25	27	manifestations	manifestation	NNS
cord-264699-l8db5gll	25	28	.	.	.
cord-264699-l8db5gll	26	1	Thus	thus	RB
cord-264699-l8db5gll	26	2	,	,	,
cord-264699-l8db5gll	26	3	infection	infection	NN
cord-264699-l8db5gll	26	4	of	of	IN
cord-264699-l8db5gll	26	5	host	host	NN
cord-264699-l8db5gll	26	6	tissues	tissue	NNS
cord-264699-l8db5gll	26	7	might	may	MD
cord-264699-l8db5gll	26	8	damage	damage	VB
cord-264699-l8db5gll	26	9	infected	infected	JJ
cord-264699-l8db5gll	26	10	organs	organ	NNS
cord-264699-l8db5gll	26	11	and	and	CC
cord-264699-l8db5gll	26	12	tissues	tissue	NNS
cord-264699-l8db5gll	26	13	directly	directly	RB
cord-264699-l8db5gll	26	14	.	.	.
cord-264699-l8db5gll	27	1	By	by	IN
cord-264699-l8db5gll	27	2	contrast	contrast	NN
cord-264699-l8db5gll	27	3	,	,	,
cord-264699-l8db5gll	27	4	viruses	virus	NNS
cord-264699-l8db5gll	27	5	themselves	-PRON-	PRP
cord-264699-l8db5gll	27	6	and	and	CC
cord-264699-l8db5gll	27	7	tissues	tissue	NNS
cord-264699-l8db5gll	27	8	that	that	WDT
cord-264699-l8db5gll	27	9	are	be	VBP
cord-264699-l8db5gll	27	10	infected	infect	VBN
cord-264699-l8db5gll	27	11	with	with	IN
cord-264699-l8db5gll	27	12	viruses	virus	NNS
cord-264699-l8db5gll	27	13	might	may	MD
cord-264699-l8db5gll	27	14	activate	activate	VB
cord-264699-l8db5gll	27	15	the	the	DT
cord-264699-l8db5gll	27	16	host	host	NN
cord-264699-l8db5gll	27	17	immune	immune	JJ
cord-264699-l8db5gll	27	18	reaction	reaction	NN
cord-264699-l8db5gll	27	19	,	,	,
cord-264699-l8db5gll	27	20	leading	lead	VBG
cord-264699-l8db5gll	27	21	to	to	IN
cord-264699-l8db5gll	27	22	the	the	DT
cord-264699-l8db5gll	27	23	development	development	NN
cord-264699-l8db5gll	27	24	of	of	IN
cord-264699-l8db5gll	27	25	inflammatory	inflammatory	JJ
cord-264699-l8db5gll	27	26	lesions	lesion	NNS
cord-264699-l8db5gll	27	27	and/or	and/or	CC
cord-264699-l8db5gll	27	28	the	the	DT
cord-264699-l8db5gll	27	29	destruction	destruction	NN
cord-264699-l8db5gll	27	30	of	of	IN
cord-264699-l8db5gll	27	31	infected	infected	JJ
cord-264699-l8db5gll	27	32	tissues	tissue	NNS
cord-264699-l8db5gll	27	33	[	[	-LRB-
cord-264699-l8db5gll	27	34	4	4	CD
cord-264699-l8db5gll	27	35	]	]	-RRB-
cord-264699-l8db5gll	27	36	.	.	.
cord-264699-l8db5gll	28	1	In	in	IN
cord-264699-l8db5gll	28	2	addition	addition	NN
cord-264699-l8db5gll	28	3	,	,	,
cord-264699-l8db5gll	28	4	host	host	NN
cord-264699-l8db5gll	28	5	immune	immune	JJ
cord-264699-l8db5gll	28	6	responses	response	NNS
cord-264699-l8db5gll	28	7	induced	induce	VBN
cord-264699-l8db5gll	28	8	against	against	IN
cord-264699-l8db5gll	28	9	viruses	virus	NNS
cord-264699-l8db5gll	28	10	and	and	CC
cord-264699-l8db5gll	28	11	infected	infected	JJ
cord-264699-l8db5gll	28	12	tissues	tissue	NNS
cord-264699-l8db5gll	28	13	might	may	MD
cord-264699-l8db5gll	28	14	damage	damage	VB
cord-264699-l8db5gll	28	15	uninfected	uninfected	JJ
cord-264699-l8db5gll	28	16	tissues	tissue	NNS
cord-264699-l8db5gll	28	17	,	,	,
cord-264699-l8db5gll	28	18	partly	partly	RB
cord-264699-l8db5gll	28	19	because	because	IN
cord-264699-l8db5gll	28	20	of	of	IN
cord-264699-l8db5gll	28	21	the	the	DT
cord-264699-l8db5gll	28	22	similarity	similarity	NN
cord-264699-l8db5gll	28	23	between	between	IN
cord-264699-l8db5gll	28	24	viral	viral	JJ
cord-264699-l8db5gll	28	25	antigens	antigen	NNS
cord-264699-l8db5gll	28	26	and	and	CC
cord-264699-l8db5gll	28	27	those	those	DT
cord-264699-l8db5gll	28	28	of	of	IN
cord-264699-l8db5gll	28	29	host	host	NN
cord-264699-l8db5gll	28	30	cells	cell	NNS
cord-264699-l8db5gll	28	31	(	(	-LRB-
cord-264699-l8db5gll	28	32	molecular	molecular	JJ
cord-264699-l8db5gll	28	33	mimicry	mimicry	NN
cord-264699-l8db5gll	28	34	)	)	-RRB-
cord-264699-l8db5gll	28	35	,	,	,
cord-264699-l8db5gll	28	36	and	and	CC
cord-264699-l8db5gll	28	37	because	because	IN
cord-264699-l8db5gll	28	38	of	of	IN
cord-264699-l8db5gll	28	39	a	a	DT
cord-264699-l8db5gll	28	40	systemic	systemic	JJ
cord-264699-l8db5gll	28	41	,	,	,
cord-264699-l8db5gll	28	42	generalized	generalize	VBD
cord-264699-l8db5gll	28	43	inflammatory	inflammatory	JJ
cord-264699-l8db5gll	28	44	reaction	reaction	NN
cord-264699-l8db5gll	28	45	that	that	WDT
cord-264699-l8db5gll	28	46	results	result	VBZ
cord-264699-l8db5gll	28	47	in	in	IN
cord-264699-l8db5gll	28	48	dysfunction	dysfunction	NN
cord-264699-l8db5gll	28	49	of	of	IN
cord-264699-l8db5gll	28	50	multiple	multiple	JJ
cord-264699-l8db5gll	28	51	organs	organ	NNS
cord-264699-l8db5gll	28	52	[	[	-LRB-
cord-264699-l8db5gll	28	53	5	5	CD
cord-264699-l8db5gll	28	54	]	]	-RRB-
cord-264699-l8db5gll	28	55	.	.	.
cord-264699-l8db5gll	29	1	Viral	viral	JJ
cord-264699-l8db5gll	29	2	-	-	HYPH
cord-264699-l8db5gll	29	3	induced	induce	VBN
cord-264699-l8db5gll	29	4	inflammation	inflammation	NN
cord-264699-l8db5gll	29	5	and	and	CC
cord-264699-l8db5gll	29	6	viremia	viremia	NN
cord-264699-l8db5gll	29	7	also	also	RB
cord-264699-l8db5gll	29	8	activate	activate	VBP
cord-264699-l8db5gll	29	9	the	the	DT
cord-264699-l8db5gll	29	10	systemic	systemic	JJ
cord-264699-l8db5gll	29	11	stress	stress	NN
cord-264699-l8db5gll	29	12	response	response	NN
cord-264699-l8db5gll	29	13	,	,	,
cord-264699-l8db5gll	29	14	in	in	IN
cord-264699-l8db5gll	29	15	which	which	WDT
cord-264699-l8db5gll	29	16	the	the	DT
cord-264699-l8db5gll	29	17	hypothalamicpituitary	hypothalamicpituitary	JJ
cord-264699-l8db5gll	29	18	-	-	HYPH
cord-264699-l8db5gll	29	19	adrenal	adrenal	JJ
cord-264699-l8db5gll	29	20	(	(	-LRB-
cord-264699-l8db5gll	29	21	HPA	HPA	NNP
cord-264699-l8db5gll	29	22	)	)	-RRB-
cord-264699-l8db5gll	29	23	axis	axis	NN
cord-264699-l8db5gll	29	24	has	have	VBZ
cord-264699-l8db5gll	29	25	a	a	DT
cord-264699-l8db5gll	29	26	major	major	JJ
cord-264699-l8db5gll	29	27	role	role	NN
cord-264699-l8db5gll	29	28	.	.	.
cord-264699-l8db5gll	30	1	Secreted	secreted	JJ
cord-264699-l8db5gll	30	2	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	30	3	,	,	,
cord-264699-l8db5gll	30	4	the	the	DT
cord-264699-l8db5gll	30	5	end	end	NN
cord-264699-l8db5gll	30	6	-	-	HYPH
cord-264699-l8db5gll	30	7	effectors	effector	NNS
cord-264699-l8db5gll	30	8	of	of	IN
cord-264699-l8db5gll	30	9	the	the	DT
cord-264699-l8db5gll	30	10	HPA	HPA	NNP
cord-264699-l8db5gll	30	11	axis	axis	NN
cord-264699-l8db5gll	30	12	,	,	,
cord-264699-l8db5gll	30	13	protect	protect	VBP
cord-264699-l8db5gll	30	14	peripheral	peripheral	JJ
cord-264699-l8db5gll	30	15	organs	organ	NNS
cord-264699-l8db5gll	30	16	from	from	IN
cord-264699-l8db5gll	30	17	inflammation	inflammation	NN
cord-264699-l8db5gll	30	18	-	-	HYPH
cord-264699-l8db5gll	30	19	induced	induce	VBN
cord-264699-l8db5gll	30	20	tissue	tissue	NN
cord-264699-l8db5gll	30	21	damage	damage	NN
cord-264699-l8db5gll	30	22	by	by	IN
cord-264699-l8db5gll	30	23	suppressing	suppress	VBG
cord-264699-l8db5gll	30	24	an	an	DT
cord-264699-l8db5gll	30	25	overshoot	overshoot	NN
cord-264699-l8db5gll	30	26	of	of	IN
cord-264699-l8db5gll	30	27	the	the	DT
cord-264699-l8db5gll	30	28	host	host	NN
cord-264699-l8db5gll	30	29	immune	immune	JJ
cord-264699-l8db5gll	30	30	reaction	reaction	NN
cord-264699-l8db5gll	30	31	and	and	CC
cord-264699-l8db5gll	30	32	by	by	IN
cord-264699-l8db5gll	30	33	rendering	render	VBG
cord-264699-l8db5gll	30	34	tissues	tissue	NNS
cord-264699-l8db5gll	30	35	resistant	resistant	JJ
cord-264699-l8db5gll	30	36	to	to	IN
cord-264699-l8db5gll	30	37	toxic	toxic	JJ
cord-264699-l8db5gll	30	38	inflammatory	inflammatory	JJ
cord-264699-l8db5gll	30	39	agents	agent	NNS
cord-264699-l8db5gll	30	40	[	[	-LRB-
cord-264699-l8db5gll	30	41	6	6	CD
cord-264699-l8db5gll	30	42	]	]	-RRB-
cord-264699-l8db5gll	30	43	[	[	-LRB-
cord-264699-l8db5gll	30	44	7	7	CD
cord-264699-l8db5gll	30	45	]	]	-RRB-
cord-264699-l8db5gll	30	46	[	[	-LRB-
cord-264699-l8db5gll	30	47	8	8	CD
cord-264699-l8db5gll	30	48	]	]	-RRB-
cord-264699-l8db5gll	30	49	.	.	.
cord-264699-l8db5gll	31	1	Thus	thus	RB
cord-264699-l8db5gll	31	2	,	,	,
cord-264699-l8db5gll	31	3	viral	viral	JJ
cord-264699-l8db5gll	31	4	infections	infection	NNS
cord-264699-l8db5gll	31	5	classically	classically	RB
cord-264699-l8db5gll	31	6	induce	induce	VBP
cord-264699-l8db5gll	31	7	the	the	DT
cord-264699-l8db5gll	31	8	host	host	NN
cord-264699-l8db5gll	31	9	reactions	reaction	NNS
cord-264699-l8db5gll	31	10	shown	show	VBN
cord-264699-l8db5gll	31	11	in	in	IN
cord-264699-l8db5gll	31	12	Box	Box	NNP
cord-264699-l8db5gll	31	13	1	1	CD
cord-264699-l8db5gll	31	14	and	and	CC
cord-264699-l8db5gll	31	15	Figure	Figure	NNP
cord-264699-l8db5gll	31	16	1	1	CD
cord-264699-l8db5gll	31	17	.	.	.
cord-264699-l8db5gll	32	1	Examples	example	NNS
cord-264699-l8db5gll	32	2	of	of	IN
cord-264699-l8db5gll	32	3	classic	classic	JJ
cord-264699-l8db5gll	32	4	host	host	NN
cord-264699-l8db5gll	32	5	responses	response	NNS
cord-264699-l8db5gll	32	6	to	to	IN
cord-264699-l8db5gll	32	7	viral	viral	JJ
cord-264699-l8db5gll	32	8	infections	infection	NNS
cord-264699-l8db5gll	32	9	are	be	VBP
cord-264699-l8db5gll	32	10	also	also	RB
cord-264699-l8db5gll	32	11	described	describe	VBN
cord-264699-l8db5gll	32	12	in	in	IN
cord-264699-l8db5gll	32	13	Table	Table	NNP
cord-264699-l8db5gll	32	14	1	1	CD
cord-264699-l8db5gll	32	15	.	.	.
cord-264699-l8db5gll	33	1	both	both	DT
cord-264699-l8db5gll	33	2	host	host	NN
cord-264699-l8db5gll	33	3	-	-	:
cord-264699-l8db5gll	33	4	and	and	CC
cord-264699-l8db5gll	33	5	virus	virus	NN
cord-264699-l8db5gll	33	6	-	-	HYPH
cord-264699-l8db5gll	33	7	encoded	encode	VBN
cord-264699-l8db5gll	33	8	molecules	molecule	NNS
cord-264699-l8db5gll	33	9	in	in	IN
cord-264699-l8db5gll	33	10	the	the	DT
cord-264699-l8db5gll	33	11	regulation	regulation	NN
cord-264699-l8db5gll	33	12	of	of	IN
cord-264699-l8db5gll	33	13	gene	gene	NN
cord-264699-l8db5gll	33	14	expression	expression	NN
cord-264699-l8db5gll	33	15	and	and	CC
cord-264699-l8db5gll	33	16	function	function	NN
cord-264699-l8db5gll	33	17	.	.	.
cord-264699-l8db5gll	34	1	Numerous	numerous	JJ
cord-264699-l8db5gll	34	2	cell	cell	NN
cord-264699-l8db5gll	34	3	-	-	HYPH
cord-264699-l8db5gll	34	4	surface	surface	NN
cord-264699-l8db5gll	34	5	molecules	molecule	NNS
cord-264699-l8db5gll	34	6	and	and	CC
cord-264699-l8db5gll	34	7	nuclear	nuclear	JJ
cord-264699-l8db5gll	34	8	hormone	hormone	NN
cord-264699-l8db5gll	34	9	receptors	receptor	NNS
cord-264699-l8db5gll	34	10	(	(	-LRB-
cord-264699-l8db5gll	34	11	NRs	NRs	NNP
cord-264699-l8db5gll	34	12	)	)	-RRB-
cord-264699-l8db5gll	34	13	that	that	WDT
cord-264699-l8db5gll	34	14	transduce	transduce	VBP
cord-264699-l8db5gll	34	15	the	the	DT
cord-264699-l8db5gll	34	16	signals	signal	NNS
cord-264699-l8db5gll	34	17	of	of	IN
cord-264699-l8db5gll	34	18	circulating	circulate	VBG
cord-264699-l8db5gll	34	19	hormones	hormone	NNS
cord-264699-l8db5gll	34	20	in	in	IN
cord-264699-l8db5gll	34	21	the	the	DT
cord-264699-l8db5gll	34	22	cytoplasm	cytoplasm	NN
cord-264699-l8db5gll	35	1	and/or	and/or	CC
cord-264699-l8db5gll	36	1	the	the	DT
cord-264699-l8db5gll	36	2	nucleus	nucleus	NN
cord-264699-l8db5gll	36	3	have	have	VBP
cord-264699-l8db5gll	36	4	been	be	VBN
cord-264699-l8db5gll	36	5	identified	identify	VBN
cord-264699-l8db5gll	36	6	and	and	CC
cord-264699-l8db5gll	36	7	their	-PRON-	PRP$
cord-264699-l8db5gll	36	8	biological	biological	JJ
cord-264699-l8db5gll	36	9	functions	function	NNS
cord-264699-l8db5gll	36	10	have	have	VBP
cord-264699-l8db5gll	36	11	been	be	VBN
cord-264699-l8db5gll	36	12	elucidated	elucidate	VBN
cord-264699-l8db5gll	36	13	.	.	.
cord-264699-l8db5gll	37	1	In	in	IN
cord-264699-l8db5gll	37	2	parallel	parallel	NN
cord-264699-l8db5gll	37	3	,	,	,
cord-264699-l8db5gll	37	4	it	-PRON-	PRP
cord-264699-l8db5gll	37	5	has	have	VBZ
cord-264699-l8db5gll	37	6	become	become	VBN
cord-264699-l8db5gll	37	7	evident	evident	JJ
cord-264699-l8db5gll	37	8	that	that	IN
cord-264699-l8db5gll	37	9	some	some	DT
cord-264699-l8db5gll	37	10	viruses	virus	NNS
cord-264699-l8db5gll	37	11	cause	cause	VBP
cord-264699-l8db5gll	37	12	pathological	pathological	JJ
cord-264699-l8db5gll	37	13	changes	change	NNS
cord-264699-l8db5gll	37	14	because	because	IN
cord-264699-l8db5gll	37	15	they	-PRON-	PRP
cord-264699-l8db5gll	37	16	encode	encode	VBP
cord-264699-l8db5gll	37	17	molecules	molecule	NNS
cord-264699-l8db5gll	37	18	that	that	WDT
cord-264699-l8db5gll	37	19	affect	affect	VBP
cord-264699-l8db5gll	37	20	host	host	NN
cord-264699-l8db5gll	37	21	signaling	signal	VBG
cord-264699-l8db5gll	37	22	pathways	pathway	NNS
cord-264699-l8db5gll	37	23	directly	directly	RB
cord-264699-l8db5gll	37	24	[	[	-LRB-
cord-264699-l8db5gll	37	25	9	9	CD
cord-264699-l8db5gll	37	26	,	,	,
cord-264699-l8db5gll	37	27	10	10	CD
cord-264699-l8db5gll	37	28	]	]	-RRB-
cord-264699-l8db5gll	37	29	and	and	CC
cord-264699-l8db5gll	37	30	these	these	DT
cord-264699-l8db5gll	37	31	actions	action	NNS
cord-264699-l8db5gll	37	32	sometimes	sometimes	RB
cord-264699-l8db5gll	37	33	cause	cause	VBP
cord-264699-l8db5gll	37	34	serious	serious	JJ
cord-264699-l8db5gll	37	35	clinical	clinical	JJ
cord-264699-l8db5gll	37	36	problems	problem	NNS
cord-264699-l8db5gll	37	37	(	(	-LRB-
cord-264699-l8db5gll	37	38	Table	table	NN
cord-264699-l8db5gll	37	39	2	2	CD
cord-264699-l8db5gll	37	40	)	)	-RRB-
cord-264699-l8db5gll	37	41	[	[	-LRB-
cord-264699-l8db5gll	37	42	10	10	CD
cord-264699-l8db5gll	37	43	,	,	,
cord-264699-l8db5gll	37	44	11	11	CD
cord-264699-l8db5gll	37	45	]	]	-RRB-
cord-264699-l8db5gll	37	46	.	.	.
cord-264699-l8db5gll	38	1	Indeed	indeed	RB
cord-264699-l8db5gll	38	2	,	,	,
cord-264699-l8db5gll	38	3	viruses	virus	NNS
cord-264699-l8db5gll	38	4	have	have	VBP
cord-264699-l8db5gll	38	5	developed	develop	VBN
cord-264699-l8db5gll	38	6	some	some	DT
cord-264699-l8db5gll	38	7	of	of	IN
cord-264699-l8db5gll	38	8	their	-PRON-	PRP$
cord-264699-l8db5gll	38	9	unique	unique	JJ
cord-264699-l8db5gll	38	10	,	,	,
cord-264699-l8db5gll	38	11	highly	highly	RB
cord-264699-l8db5gll	38	12	sophisticated	sophisticated	JJ
cord-264699-l8db5gll	38	13	molecules	molecule	NNS
cord-264699-l8db5gll	38	14	through	through	IN
cord-264699-l8db5gll	38	15	the	the	DT
cord-264699-l8db5gll	38	16	mutational	mutational	JJ
cord-264699-l8db5gll	38	17	selection	selection	NN
cord-264699-l8db5gll	38	18	of	of	IN
cord-264699-l8db5gll	38	19	protein	protein	NN
cord-264699-l8db5gll	38	20	isoforms	isoform	NNS
cord-264699-l8db5gll	38	21	that	that	WDT
cord-264699-l8db5gll	38	22	increase	increase	VBP
cord-264699-l8db5gll	38	23	the	the	DT
cord-264699-l8db5gll	38	24	chance	chance	NN
cord-264699-l8db5gll	38	25	of	of	IN
cord-264699-l8db5gll	38	26	their	-PRON-	PRP$
cord-264699-l8db5gll	38	27	replication	replication	NN
cord-264699-l8db5gll	38	28	and/or	and/or	CC
cord-264699-l8db5gll	38	29	survival	survival	NN
cord-264699-l8db5gll	38	30	inside	inside	IN
cord-264699-l8db5gll	38	31	infected	infected	JJ
cord-264699-l8db5gll	38	32	cells	cell	NNS
cord-264699-l8db5gll	38	33	,	,	,
cord-264699-l8db5gll	38	34	and	and	CC
cord-264699-l8db5gll	38	35	their	-PRON-	PRP$
cord-264699-l8db5gll	38	36	propagation	propagation	NN
cord-264699-l8db5gll	38	37	from	from	IN
cord-264699-l8db5gll	38	38	cell	cell	NN
cord-264699-l8db5gll	38	39	-	-	HYPH
cord-264699-l8db5gll	38	40	to	to	IN
cord-264699-l8db5gll	38	41	-	-	HYPH
cord-264699-l8db5gll	38	42	cell	cell	NN
cord-264699-l8db5gll	38	43	and	and	CC
cord-264699-l8db5gll	38	44	host	host	NN
cord-264699-l8db5gll	38	45	-	-	HYPH
cord-264699-l8db5gll	38	46	to	to	IN
cord-264699-l8db5gll	38	47	-	-	HYPH
cord-264699-l8db5gll	38	48	host	host	NN
cord-264699-l8db5gll	38	49	.	.	.
cord-264699-l8db5gll	39	1	These	these	DT
cord-264699-l8db5gll	39	2	viral	viral	JJ
cord-264699-l8db5gll	39	3	molecules	molecule	NNS
cord-264699-l8db5gll	39	4	regularly	regularly	RB
cord-264699-l8db5gll	39	5	influence	influence	VBP
cord-264699-l8db5gll	39	6	crucial	crucial	JJ
cord-264699-l8db5gll	39	7	steps	step	NNS
cord-264699-l8db5gll	39	8	in	in	IN
cord-264699-l8db5gll	39	9	host	host	NN
cord-264699-l8db5gll	39	10	signaling	signal	VBG
cord-264699-l8db5gll	39	11	systems	system	NNS
cord-264699-l8db5gll	39	12	and	and	CC
cord-264699-l8db5gll	39	13	,	,	,
cord-264699-l8db5gll	39	14	thus	thus	RB
cord-264699-l8db5gll	39	15	,	,	,
cord-264699-l8db5gll	39	16	dramatically	dramatically	RB
cord-264699-l8db5gll	39	17	change	change	VBP
cord-264699-l8db5gll	39	18	cellular	cellular	JJ
cord-264699-l8db5gll	39	19	functions	function	NNS
cord-264699-l8db5gll	39	20	towards	towards	IN
cord-264699-l8db5gll	39	21	conditions	condition	NNS
cord-264699-l8db5gll	39	22	that	that	WDT
cord-264699-l8db5gll	39	23	are	be	VBP
cord-264699-l8db5gll	39	24	beneficial	beneficial	JJ
cord-264699-l8db5gll	39	25	to	to	IN
cord-264699-l8db5gll	39	26	the	the	DT
cord-264699-l8db5gll	39	27	replication	replication	NN
cord-264699-l8db5gll	39	28	,	,	,
cord-264699-l8db5gll	39	29	survival	survival	NN
cord-264699-l8db5gll	39	30	and/or	and/or	CC
cord-264699-l8db5gll	39	31	propagation	propagation	NN
cord-264699-l8db5gll	39	32	of	of	IN
cord-264699-l8db5gll	39	33	the	the	DT
cord-264699-l8db5gll	39	34	viruses	virus	NNS
cord-264699-l8db5gll	39	35	that	that	WDT
cord-264699-l8db5gll	39	36	encode	encode	VBP
cord-264699-l8db5gll	39	37	them	-PRON-	PRP
cord-264699-l8db5gll	39	38	.	.	.
cord-264699-l8db5gll	40	1	Sometimes	sometimes	RB
cord-264699-l8db5gll	40	2	,	,	,
cord-264699-l8db5gll	40	3	these	these	DT
cord-264699-l8db5gll	40	4	viral	viral	JJ
cord-264699-l8db5gll	40	5	molecules	molecule	NNS
cord-264699-l8db5gll	40	6	mimic	mimic	VBP
cord-264699-l8db5gll	40	7	functions	function	NNS
cord-264699-l8db5gll	40	8	of	of	IN
cord-264699-l8db5gll	40	9	host	host	NN
cord-264699-l8db5gll	40	10	proteins	protein	NNS
cord-264699-l8db5gll	40	11	.	.	.
cord-264699-l8db5gll	41	1	For	for	IN
cord-264699-l8db5gll	41	2	example	example	NN
cord-264699-l8db5gll	41	3	,	,	,
cord-264699-l8db5gll	41	4	HIV-1-encoded	hiv-1-encode	VBN
cord-264699-l8db5gll	41	5	gp120	gp120	NNP
cord-264699-l8db5gll	41	6	molecules	molecule	NNS
cord-264699-l8db5gll	41	7	,	,	,
cord-264699-l8db5gll	41	8	which	which	WDT
cord-264699-l8db5gll	41	9	are	be	VBP
cord-264699-l8db5gll	41	10	located	locate	VBN
cord-264699-l8db5gll	41	11	on	on	IN
cord-264699-l8db5gll	41	12	the	the	DT
cord-264699-l8db5gll	41	13	surface	surface	NN
cord-264699-l8db5gll	41	14	of	of	IN
cord-264699-l8db5gll	41	15	the	the	DT
cord-264699-l8db5gll	41	16	viral	viral	JJ
cord-264699-l8db5gll	41	17	particle	particle	NN
cord-264699-l8db5gll	41	18	and	and	CC
cord-264699-l8db5gll	41	19	have	have	VB
cord-264699-l8db5gll	41	20	a	a	DT
cord-264699-l8db5gll	41	21	major	major	JJ
cord-264699-l8db5gll	41	22	role	role	NN
cord-264699-l8db5gll	41	23	in	in	IN
cord-264699-l8db5gll	41	24	the	the	DT
cord-264699-l8db5gll	41	25	entry	entry	NN
cord-264699-l8db5gll	41	26	of	of	IN
cord-264699-l8db5gll	41	27	viruses	virus	NNS
cord-264699-l8db5gll	41	28	into	into	IN
cord-264699-l8db5gll	41	29	target	target	NN
cord-264699-l8db5gll	41	30	cells	cell	NNS
cord-264699-l8db5gll	41	31	,	,	,
cord-264699-l8db5gll	41	32	demonstrate	demonstrate	VBP
cord-264699-l8db5gll	41	33	amino	amino	NN
cord-264699-l8db5gll	41	34	acid	acid	NN
cord-264699-l8db5gll	41	35	sequence	sequence	NN
cord-264699-l8db5gll	41	36	similarity	similarity	NN
cord-264699-l8db5gll	41	37	to	to	IN
cord-264699-l8db5gll	41	38	the	the	DT
cord-264699-l8db5gll	41	39	growth	growth	NN
cord-264699-l8db5gll	41	40	hormone	hormone	NN
cord-264699-l8db5gll	41	41	-	-	HYPH
cord-264699-l8db5gll	41	42	releasing	release	VBG
cord-264699-l8db5gll	41	43	hormone	hormone	NN
cord-264699-l8db5gll	41	44	(	(	-LRB-
cord-264699-l8db5gll	41	45	GHRH	GHRH	NNP
cord-264699-l8db5gll	41	46	)	)	-RRB-
cord-264699-l8db5gll	41	47	receptor	receptor	NN
cord-264699-l8db5gll	41	48	of	of	IN
cord-264699-l8db5gll	41	49	the	the	DT
cord-264699-l8db5gll	41	50	host	host	NN
cord-264699-l8db5gll	41	51	and	and	CC
cord-264699-l8db5gll	41	52	suppress	suppress	VB
cord-264699-l8db5gll	41	53	the	the	DT
cord-264699-l8db5gll	41	54	activation	activation	NN
cord-264699-l8db5gll	41	55	of	of	IN
cord-264699-l8db5gll	41	56	this	this	DT
cord-264699-l8db5gll	41	57	receptor	receptor	NN
cord-264699-l8db5gll	41	58	by	by	IN
cord-264699-l8db5gll	41	59	GHRH	GHRH	NNP
cord-264699-l8db5gll	41	60	.	.	.
cord-264699-l8db5gll	42	1	This	this	DT
cord-264699-l8db5gll	42	2	phenomenon	phenomenon	NN
cord-264699-l8db5gll	42	3	might	may	MD
cord-264699-l8db5gll	42	4	contribute	contribute	VB
cord-264699-l8db5gll	42	5	to	to	IN
cord-264699-l8db5gll	42	6	growth	growth	NN
cord-264699-l8db5gll	42	7	retardation	retardation	NN
cord-264699-l8db5gll	42	8	of	of	IN
cord-264699-l8db5gll	42	9	HIV-1-infected	hiv-1-infecte	VBN
cord-264699-l8db5gll	42	10	children	child	NNS
cord-264699-l8db5gll	42	11	[	[	-LRB-
cord-264699-l8db5gll	42	12	12	12	CD
cord-264699-l8db5gll	42	13	]	]	-RRB-
cord-264699-l8db5gll	42	14	.	.	.
cord-264699-l8db5gll	43	1	This	this	DT
cord-264699-l8db5gll	43	2	viral	viral	JJ
cord-264699-l8db5gll	43	3	molecule	molecule	NN
cord-264699-l8db5gll	43	4	is	be	VBZ
cord-264699-l8db5gll	43	5	also	also	RB
cord-264699-l8db5gll	43	6	similar	similar	JJ
cord-264699-l8db5gll	43	7	to	to	IN
cord-264699-l8db5gll	43	8	vasoactive	vasoactive	JJ
cord-264699-l8db5gll	43	9	intestinal	intestinal	JJ
cord-264699-l8db5gll	43	10	peptide	peptide	NN
cord-264699-l8db5gll	43	11	,	,	,
cord-264699-l8db5gll	43	12	which	which	WDT
cord-264699-l8db5gll	43	13	interacts	interact	VBZ
cord-264699-l8db5gll	43	14	with	with	IN
cord-264699-l8db5gll	43	15	CD4	CD4	NNP
cord-264699-l8db5gll	43	16	,	,	,
cord-264699-l8db5gll	43	17	a	a	DT
cord-264699-l8db5gll	43	18	receptor	receptor	NN
cord-264699-l8db5gll	43	19	for	for	IN
cord-264699-l8db5gll	43	20	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	43	21	,	,	,
cord-264699-l8db5gll	43	22	to	to	TO
cord-264699-l8db5gll	43	23	facilitate	facilitate	VB
cord-264699-l8db5gll	43	24	its	-PRON-	PRP$
cord-264699-l8db5gll	43	25	entry	entry	NN
cord-264699-l8db5gll	43	26	into	into	IN
cord-264699-l8db5gll	43	27	T	t	NN
cord-264699-l8db5gll	43	28	cells	cell	NNS
cord-264699-l8db5gll	43	29	[	[	-LRB-
cord-264699-l8db5gll	43	30	13	13	CD
cord-264699-l8db5gll	43	31	,	,	,
cord-264699-l8db5gll	43	32	14	14	CD
cord-264699-l8db5gll	43	33	]	]	-RRB-
cord-264699-l8db5gll	43	34	.	.	.
cord-264699-l8db5gll	44	1	The	the	DT
cord-264699-l8db5gll	44	2	amino	amino	NN
cord-264699-l8db5gll	44	3	acid	acid	NN
cord-264699-l8db5gll	44	4	sequence	sequence	NN
cord-264699-l8db5gll	44	5	of	of	IN
cord-264699-l8db5gll	44	6	the	the	DT
cord-264699-l8db5gll	44	7	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	44	8	Nef	Nef	NNP
cord-264699-l8db5gll	44	9	protein	protein	NN
cord-264699-l8db5gll	44	10	resembles	resemble	VBZ
cord-264699-l8db5gll	44	11	a	a	DT
cord-264699-l8db5gll	44	12	portion	portion	NN
cord-264699-l8db5gll	44	13	of	of	IN
cord-264699-l8db5gll	44	14	the	the	DT
cord-264699-l8db5gll	44	15	thyroid	thyroid	NN
cord-264699-l8db5gll	44	16	-	-	HYPH
cord-264699-l8db5gll	44	17	stimulating	stimulate	VBG
cord-264699-l8db5gll	44	18	hormone	hormone	NN
cord-264699-l8db5gll	44	19	receptor	receptor	NN
cord-264699-l8db5gll	44	20	,	,	,
cord-264699-l8db5gll	44	21	and	and	CC
cord-264699-l8db5gll	44	22	this	this	DT
cord-264699-l8db5gll	44	23	crossreactivity	crossreactivity	NN
cord-264699-l8db5gll	44	24	might	may	MD
cord-264699-l8db5gll	44	25	contribute	contribute	VB
cord-264699-l8db5gll	44	26	to	to	IN
cord-264699-l8db5gll	44	27	the	the	DT
cord-264699-l8db5gll	44	28	development	development	NN
cord-264699-l8db5gll	44	29	of	of	IN
cord-264699-l8db5gll	44	30	Grave	Grave	NNP
cord-264699-l8db5gll	44	31	's	's	POS
cord-264699-l8db5gll	44	32	disease	disease	NN
cord-264699-l8db5gll	44	33	in	in	IN
cord-264699-l8db5gll	44	34	HIV-1-infected	hiv-1-infecte	VBN
cord-264699-l8db5gll	44	35	patients	patient	NNS
cord-264699-l8db5gll	44	36	[	[	-LRB-
cord-264699-l8db5gll	44	37	15	15	CD
cord-264699-l8db5gll	44	38	]	]	-RRB-
cord-264699-l8db5gll	44	39	.	.	.
cord-264699-l8db5gll	45	1	In	in	IN
cord-264699-l8db5gll	45	2	addition	addition	NN
cord-264699-l8db5gll	45	3	to	to	IN
cord-264699-l8db5gll	45	4	their	-PRON-	PRP$
cord-264699-l8db5gll	45	5	extracellular	extracellular	JJ
cord-264699-l8db5gll	45	6	actions	action	NNS
cord-264699-l8db5gll	45	7	,	,	,
cord-264699-l8db5gll	45	8	many	many	JJ
cord-264699-l8db5gll	45	9	viral	viral	JJ
cord-264699-l8db5gll	45	10	molecules	molecule	NNS
cord-264699-l8db5gll	45	11	act	act	VBP
cord-264699-l8db5gll	45	12	inside	inside	IN
cord-264699-l8db5gll	45	13	infected	infected	JJ
cord-264699-l8db5gll	45	14	cells	cell	NNS
cord-264699-l8db5gll	45	15	to	to	TO
cord-264699-l8db5gll	45	16	modulate	modulate	VB
cord-264699-l8db5gll	46	1	intracellular	intracellular	JJ
cord-264699-l8db5gll	46	2	host	host	NN
cord-264699-l8db5gll	46	3	signaling	signal	VBG
cord-264699-l8db5gll	46	4	systems	system	NNS
cord-264699-l8db5gll	46	5	,	,	,
cord-264699-l8db5gll	46	6	including	include	VBG
cord-264699-l8db5gll	46	7	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	46	8	regulation	regulation	NN
cord-264699-l8db5gll	46	9	of	of	IN
cord-264699-l8db5gll	46	10	target	target	NN
cord-264699-l8db5gll	46	11	genes	gene	NNS
cord-264699-l8db5gll	46	12	by	by	IN
cord-264699-l8db5gll	46	13	hormones	hormone	NNS
cord-264699-l8db5gll	46	14	.	.	.
cord-264699-l8db5gll	47	1	These	these	DT
cord-264699-l8db5gll	47	2	molecules	molecule	NNS
cord-264699-l8db5gll	47	3	are	be	VBP
cord-264699-l8db5gll	47	4	intended	intend	VBN
cord-264699-l8db5gll	47	5	primarily	primarily	RB
cord-264699-l8db5gll	47	6	to	to	TO
cord-264699-l8db5gll	47	7	benefit	benefit	VB
cord-264699-l8db5gll	47	8	viral	viral	JJ
cord-264699-l8db5gll	47	9	replication	replication	NN
cord-264699-l8db5gll	47	10	,	,	,
cord-264699-l8db5gll	47	11	but	but	CC
cord-264699-l8db5gll	47	12	,	,	,
cord-264699-l8db5gll	47	13	frequently	frequently	RB
cord-264699-l8db5gll	47	14	,	,	,
cord-264699-l8db5gll	47	15	they	-PRON-	PRP
cord-264699-l8db5gll	47	16	alter	alter	VBP
cord-264699-l8db5gll	47	17	the	the	DT
cord-264699-l8db5gll	47	18	intracellular	intracellular	JJ
cord-264699-l8db5gll	47	19	milieu	milieu	NN
cord-264699-l8db5gll	47	20	,	,	,
cord-264699-l8db5gll	47	21	disturbing	disturb	VBG
cord-264699-l8db5gll	47	22	cellular	cellular	JJ
cord-264699-l8db5gll	47	23	functions	function	NNS
cord-264699-l8db5gll	47	24	as	as	IN
cord-264699-l8db5gll	47	25	a	a	DT
cord-264699-l8db5gll	47	26	'	'	``
cord-264699-l8db5gll	47	27	side	side	NN
cord-264699-l8db5gll	47	28	-	-	HYPH
cord-264699-l8db5gll	47	29	effect	effect	NN
cord-264699-l8db5gll	47	30	'	'	''
cord-264699-l8db5gll	47	31	and	and	CC
cord-264699-l8db5gll	47	32	causing	cause	VBG
cord-264699-l8db5gll	47	33	specific	specific	JJ
cord-264699-l8db5gll	47	34	,	,	,
cord-264699-l8db5gll	47	35	recognizable	recognizable	JJ
cord-264699-l8db5gll	47	36	,	,	,
cord-264699-l8db5gll	47	37	pathological	pathological	JJ
cord-264699-l8db5gll	47	38	conditions	condition	NNS
cord-264699-l8db5gll	47	39	[	[	-LRB-
cord-264699-l8db5gll	47	40	10	10	CD
cord-264699-l8db5gll	47	41	,	,	,
cord-264699-l8db5gll	47	42	16	16	CD
cord-264699-l8db5gll	47	43	]	]	-RRB-
cord-264699-l8db5gll	47	44	.	.	.
cord-264699-l8db5gll	48	1	In	in	IN
cord-264699-l8db5gll	48	2	the	the	DT
cord-264699-l8db5gll	48	3	following	following	JJ
cord-264699-l8db5gll	48	4	sections	section	NNS
cord-264699-l8db5gll	48	5	,	,	,
cord-264699-l8db5gll	48	6	examples	example	NNS
cord-264699-l8db5gll	48	7	of	of	IN
cord-264699-l8db5gll	48	8	extracellular	extracellular	JJ
cord-264699-l8db5gll	48	9	and	and	CC
cord-264699-l8db5gll	48	10	intracellular	intracellular	JJ
cord-264699-l8db5gll	48	11	modifications	modification	NNS
cord-264699-l8db5gll	48	12	of	of	IN
cord-264699-l8db5gll	48	13	host	host	NN
cord-264699-l8db5gll	48	14	endocrine	endocrine	JJ
cord-264699-l8db5gll	48	15	signaling	signal	VBG
cord-264699-l8db5gll	48	16	systems	system	NNS
cord-264699-l8db5gll	48	17	caused	cause	VBN
cord-264699-l8db5gll	48	18	by	by	IN
cord-264699-l8db5gll	48	19	viral	viral	JJ
cord-264699-l8db5gll	48	20	molecules	molecule	NNS
cord-264699-l8db5gll	48	21	are	be	VBP
cord-264699-l8db5gll	48	22	discussed	discuss	VBN
cord-264699-l8db5gll	48	23	.	.	.
cord-264699-l8db5gll	49	1	Human	human	JJ
cord-264699-l8db5gll	49	2	T	t	NN
cord-264699-l8db5gll	49	3	-	-	HYPH
cord-264699-l8db5gll	49	4	cell	cell	NN
cord-264699-l8db5gll	49	5	leukemia	leukemia	NN
cord-264699-l8db5gll	49	6	(	(	-LRB-
cord-264699-l8db5gll	49	7	lymphotrophic	lymphotrophic	NNP
cord-264699-l8db5gll	49	8	)	)	-RRB-
cord-264699-l8db5gll	49	9	virus	virus	NN
cord-264699-l8db5gll	49	10	type	type	NN
cord-264699-l8db5gll	49	11	1	1	CD
cord-264699-l8db5gll	49	12	(	(	-LRB-
cord-264699-l8db5gll	49	13	HTLV-1	HTLV-1	NNP
cord-264699-l8db5gll	49	14	)	)	-RRB-
cord-264699-l8db5gll	49	15	,	,	,
cord-264699-l8db5gll	49	16	the	the	DT
cord-264699-l8db5gll	49	17	single	single	RB
cord-264699-l8db5gll	49	18	-	-	HYPH
cord-264699-l8db5gll	49	19	stranded	strand	VBN
cord-264699-l8db5gll	49	20	RNA	RNA	NNP
cord-264699-l8db5gll	49	21	virus	virus	NN
cord-264699-l8db5gll	49	22	of	of	IN
cord-264699-l8db5gll	49	23	the	the	DT
cord-264699-l8db5gll	49	24	Retroviridae	Retroviridae	NNP
cord-264699-l8db5gll	49	25	family	family	NN
cord-264699-l8db5gll	49	26	that	that	WDT
cord-264699-l8db5gll	49	27	specifically	specifically	RB
cord-264699-l8db5gll	49	28	infects	infect	VBZ
cord-264699-l8db5gll	49	29	CD4-positive	CD4-positive	NNP
cord-264699-l8db5gll	49	30	T	t	NN
cord-264699-l8db5gll	49	31	cells	cell	NNS
cord-264699-l8db5gll	49	32	,	,	,
cord-264699-l8db5gll	49	33	is	be	VBZ
cord-264699-l8db5gll	49	34	a	a	DT
cord-264699-l8db5gll	49	35	causative	causative	JJ
cord-264699-l8db5gll	49	36	agent	agent	NN
cord-264699-l8db5gll	49	37	of	of	IN
cord-264699-l8db5gll	49	38	adult	adult	NN
cord-264699-l8db5gll	49	39	T	t	NN
cord-264699-l8db5gll	49	40	-	-	HYPH
cord-264699-l8db5gll	49	41	cell	cell	NN
cord-264699-l8db5gll	49	42	leukemia	leukemia	NN
cord-264699-l8db5gll	49	43	(	(	-LRB-
cord-264699-l8db5gll	49	44	ATL	ATL	NNP
cord-264699-l8db5gll	49	45	)	)	-RRB-
cord-264699-l8db5gll	49	46	and	and	CC
cord-264699-l8db5gll	49	47	HTLV	HTLV	NNP
cord-264699-l8db5gll	49	48	-	-	HYPH
cord-264699-l8db5gll	49	49	associated	associate	VBN
cord-264699-l8db5gll	49	50	myelopathy	myelopathy	NN
cord-264699-l8db5gll	49	51	[	[	-LRB-
cord-264699-l8db5gll	49	52	11	11	CD
cord-264699-l8db5gll	49	53	]	]	-RRB-
cord-264699-l8db5gll	49	54	.	.	.
cord-264699-l8db5gll	50	1	ATL	ATL	NNP
cord-264699-l8db5gll	50	2	patients	patient	NNS
cord-264699-l8db5gll	50	3	infected	infect	VBN
cord-264699-l8db5gll	50	4	with	with	IN
cord-264699-l8db5gll	50	5	HTLV-1	HTLV-1	NNP
cord-264699-l8db5gll	50	6	may	may	MD
cord-264699-l8db5gll	50	7	also	also	RB
cord-264699-l8db5gll	50	8	develop	develop	VB
cord-264699-l8db5gll	50	9	hypercalcemia	hypercalcemia	NN
cord-264699-l8db5gll	50	10	because	because	IN
cord-264699-l8db5gll	50	11	of	of	IN
cord-264699-l8db5gll	50	12	aberrant	aberrant	JJ
cord-264699-l8db5gll	50	13	expression	expression	NN
cord-264699-l8db5gll	50	14	of	of	IN
cord-264699-l8db5gll	50	15	parathyroid	parathyroid	JJ
cord-264699-l8db5gll	50	16	hormone	hormone	NN
cord-264699-l8db5gll	50	17	(	(	-LRB-
cord-264699-l8db5gll	50	18	PTH)-related	PTH)-related	NNP
cord-264699-l8db5gll	50	19	protein	protein	NN
cord-264699-l8db5gll	50	20	(	(	-LRB-
cord-264699-l8db5gll	50	21	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	50	22	)	)	-RRB-
cord-264699-l8db5gll	51	1	[	[	-LRB-
cord-264699-l8db5gll	51	2	17	17	CD
cord-264699-l8db5gll	51	3	]	]	-RRB-
cord-264699-l8db5gll	51	4	.	.	.
cord-264699-l8db5gll	52	1	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	52	2	is	be	VBZ
cord-264699-l8db5gll	52	3	a	a	DT
cord-264699-l8db5gll	52	4	141	141	CD
cord-264699-l8db5gll	52	5	amino	amino	NN
cord-264699-l8db5gll	52	6	acid	acid	NN
cord-264699-l8db5gll	52	7	protein	protein	NN
cord-264699-l8db5gll	52	8	that	that	WDT
cord-264699-l8db5gll	52	9	shares	share	VBZ
cord-264699-l8db5gll	52	10	significant	significant	JJ
cord-264699-l8db5gll	52	11	N	n	CD
cord-264699-l8db5gll	52	12	-	-	HYPH
cord-264699-l8db5gll	52	13	terminal	terminal	NN
cord-264699-l8db5gll	52	14	sequence	sequence	NN
cord-264699-l8db5gll	52	15	homology	homology	NN
cord-264699-l8db5gll	52	16	Box	Box	NNP
cord-264699-l8db5gll	52	17	1	1	CD
cord-264699-l8db5gll	52	18	.	.	.
cord-264699-l8db5gll	53	1	Virus	virus	NN
cord-264699-l8db5gll	53	2	-	-	HYPH
cord-264699-l8db5gll	53	3	induced	induce	VBN
cord-264699-l8db5gll	53	4	alterations	alteration	NNS
cord-264699-l8db5gll	53	5	of	of	IN
cord-264699-l8db5gll	53	6	the	the	DT
cord-264699-l8db5gll	53	7	host	host	NN
cord-264699-l8db5gll	53	8	endocrine	endocrine	NN
cord-264699-l8db5gll	53	9	system	system	NN
cord-264699-l8db5gll	53	10	Activation	Activation	NNP
cord-264699-l8db5gll	53	11	of	of	IN
cord-264699-l8db5gll	53	12	the	the	DT
cord-264699-l8db5gll	53	13	HPA	HPA	NNP
cord-264699-l8db5gll	53	14	axis	axis	NN
cord-264699-l8db5gll	53	15	/	/	SYM
cord-264699-l8db5gll	53	16	stress	stress	NN
cord-264699-l8db5gll	53	17	system	system	NN
cord-264699-l8db5gll	53	18	indirectly	indirectly	RB
cord-264699-l8db5gll	53	19	,	,	,
cord-264699-l8db5gll	53	20	as	as	IN
cord-264699-l8db5gll	53	21	a	a	DT
cord-264699-l8db5gll	53	22	result	result	NN
cord-264699-l8db5gll	53	23	of	of	IN
cord-264699-l8db5gll	53	24	a	a	DT
cord-264699-l8db5gll	53	25	general	general	JJ
cord-264699-l8db5gll	53	26	inflammatory	inflammatory	JJ
cord-264699-l8db5gll	53	27	response	response	NN
cord-264699-l8db5gll	53	28	to	to	IN
cord-264699-l8db5gll	53	29	the	the	DT
cord-264699-l8db5gll	53	30	systemic	systemic	JJ
cord-264699-l8db5gll	53	31	viral	viral	JJ
cord-264699-l8db5gll	53	32	infection	infection	NN
cord-264699-l8db5gll	53	33	and	and	CC
cord-264699-l8db5gll	53	34	secretion	secretion	NN
cord-264699-l8db5gll	53	35	of	of	IN
cord-264699-l8db5gll	53	36	mediators	mediator	NNS
cord-264699-l8db5gll	53	37	of	of	IN
cord-264699-l8db5gll	53	38	inflammation	inflammation	NN
cord-264699-l8db5gll	53	39	with	with	IN
cord-264699-l8db5gll	53	40	stress	stress	NN
cord-264699-l8db5gll	53	41	systemstimulating	systemstimulating	NN
cord-264699-l8db5gll	53	42	activity	activity	NN
cord-264699-l8db5gll	53	43	.	.	.
cord-264699-l8db5gll	54	1	Damage	damage	NN
cord-264699-l8db5gll	54	2	of	of	IN
cord-264699-l8db5gll	54	3	virus	virus	NN
cord-264699-l8db5gll	54	4	-	-	HYPH
cord-264699-l8db5gll	54	5	infected	infect	VBN
cord-264699-l8db5gll	54	6	endocrine	endocrine	JJ
cord-264699-l8db5gll	54	7	cells	cell	NNS
cord-264699-l8db5gll	54	8	by	by	IN
cord-264699-l8db5gll	54	9	viral	viral	JJ
cord-264699-l8db5gll	54	10	replication	replication	NN
cord-264699-l8db5gll	54	11	,	,	,
cord-264699-l8db5gll	54	12	proliferation	proliferation	NN
cord-264699-l8db5gll	54	13	and	and	CC
cord-264699-l8db5gll	54	14	assembly	assembly	NN
cord-264699-l8db5gll	54	15	.	.	.
cord-264699-l8db5gll	55	1	Damage	damage	NN
cord-264699-l8db5gll	55	2	of	of	IN
cord-264699-l8db5gll	55	3	virus	virus	NN
cord-264699-l8db5gll	55	4	-	-	HYPH
cord-264699-l8db5gll	55	5	infected	infect	VBN
cord-264699-l8db5gll	55	6	endocrine	endocrine	JJ
cord-264699-l8db5gll	55	7	organs	organ	NNS
cord-264699-l8db5gll	55	8	by	by	IN
cord-264699-l8db5gll	55	9	activation	activation	NN
cord-264699-l8db5gll	55	10	of	of	IN
cord-264699-l8db5gll	55	11	the	the	DT
cord-264699-l8db5gll	55	12	immune	immune	JJ
cord-264699-l8db5gll	55	13	reaction	reaction	NN
cord-264699-l8db5gll	55	14	against	against	IN
cord-264699-l8db5gll	55	15	these	these	DT
cord-264699-l8db5gll	55	16	organs	organ	NNS
cord-264699-l8db5gll	55	17	.	.	.
cord-264699-l8db5gll	56	1	Damage	damage	NN
cord-264699-l8db5gll	56	2	against	against	IN
cord-264699-l8db5gll	56	3	uninfected	uninfected	JJ
cord-264699-l8db5gll	56	4	endocrine	endocrine	JJ
cord-264699-l8db5gll	56	5	organs	organ	NNS
cord-264699-l8db5gll	56	6	through	through	IN
cord-264699-l8db5gll	56	7	an	an	DT
cord-264699-l8db5gll	56	8	autoimmune	autoimmune	JJ
cord-264699-l8db5gll	56	9	mechanism	mechanism	NN
cord-264699-l8db5gll	56	10	.	.	.
cord-264699-l8db5gll	57	1	Alteration	alteration	NN
cord-264699-l8db5gll	57	2	of	of	IN
cord-264699-l8db5gll	57	3	hormonal	hormonal	JJ
cord-264699-l8db5gll	57	4	activity	activity	NN
cord-264699-l8db5gll	57	5	and/or	and/or	CC
cord-264699-l8db5gll	57	6	hormone	hormone	NN
cord-264699-l8db5gll	57	7	secretion	secretion	NN
cord-264699-l8db5gll	57	8	by	by	IN
cord-264699-l8db5gll	57	9	viral	viral	JJ
cord-264699-l8db5gll	57	10	gene	gene	NN
cord-264699-l8db5gll	57	11	products	product	NNS
cord-264699-l8db5gll	57	12	.	.	.
cord-264699-l8db5gll	58	1	with	with	IN
cord-264699-l8db5gll	58	2	PTH	PTH	NNP
cord-264699-l8db5gll	58	3	[	[	-LRB-
cord-264699-l8db5gll	58	4	18	18	CD
cord-264699-l8db5gll	58	5	]	]	-RRB-
cord-264699-l8db5gll	58	6	.	.	.
cord-264699-l8db5gll	59	1	In	in	IN
cord-264699-l8db5gll	59	2	humans	human	NNS
cord-264699-l8db5gll	59	3	,	,	,
cord-264699-l8db5gll	59	4	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	59	5	is	be	VBZ
cord-264699-l8db5gll	59	6	present	present	JJ
cord-264699-l8db5gll	59	7	in	in	IN
cord-264699-l8db5gll	59	8	many	many	JJ
cord-264699-l8db5gll	59	9	normal	normal	JJ
cord-264699-l8db5gll	59	10	and	and	CC
cord-264699-l8db5gll	59	11	neoplastic	neoplastic	JJ
cord-264699-l8db5gll	59	12	tissues	tissue	NNS
cord-264699-l8db5gll	59	13	,	,	,
cord-264699-l8db5gll	59	14	whereas	whereas	IN
cord-264699-l8db5gll	59	15	PTH	PTH	NNP
cord-264699-l8db5gll	59	16	is	be	VBZ
cord-264699-l8db5gll	59	17	present	present	JJ
cord-264699-l8db5gll	59	18	only	only	RB
cord-264699-l8db5gll	59	19	in	in	IN
cord-264699-l8db5gll	59	20	the	the	DT
cord-264699-l8db5gll	59	21	parathyroid	parathyroid	JJ
cord-264699-l8db5gll	59	22	gland	gland	NN
cord-264699-l8db5gll	59	23	[	[	-LRB-
cord-264699-l8db5gll	59	24	18	18	CD
cord-264699-l8db5gll	59	25	]	]	-RRB-
cord-264699-l8db5gll	59	26	.	.	.
cord-264699-l8db5gll	60	1	Leukemic	Leukemic	NNP
cord-264699-l8db5gll	60	2	cells	cell	NNS
cord-264699-l8db5gll	60	3	from	from	IN
cord-264699-l8db5gll	60	4	ATL	ATL	NNP
cord-264699-l8db5gll	60	5	patients	patient	NNS
cord-264699-l8db5gll	60	6	,	,	,
cord-264699-l8db5gll	60	7	as	as	RB
cord-264699-l8db5gll	60	8	well	well	RB
cord-264699-l8db5gll	60	9	as	as	IN
cord-264699-l8db5gll	60	10	lymphocytes	lymphocyte	NNS
cord-264699-l8db5gll	60	11	from	from	IN
cord-264699-l8db5gll	60	12	asymptomatic	asymptomatic	JJ
cord-264699-l8db5gll	60	13	HTLV-1-positive	htlv-1-positive	JJ
cord-264699-l8db5gll	60	14	carriers	carrier	NNS
cord-264699-l8db5gll	60	15	,	,	,
cord-264699-l8db5gll	60	16	contain	contain	VBP
cord-264699-l8db5gll	60	17	high	high	JJ
cord-264699-l8db5gll	60	18	levels	level	NNS
cord-264699-l8db5gll	60	19	of	of	IN
cord-264699-l8db5gll	60	20	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	60	21	;	;	:
cord-264699-l8db5gll	60	22	the	the	DT
cord-264699-l8db5gll	60	23	secreted	secrete	VBN
cord-264699-l8db5gll	60	24	protein	protein	NN
cord-264699-l8db5gll	60	25	exerts	exert	VBZ
cord-264699-l8db5gll	60	26	biological	biological	JJ
cord-264699-l8db5gll	60	27	effects	effect	NNS
cord-264699-l8db5gll	60	28	that	that	WDT
cord-264699-l8db5gll	60	29	are	be	VBP
cord-264699-l8db5gll	60	30	similar	similar	JJ
cord-264699-l8db5gll	60	31	to	to	IN
cord-264699-l8db5gll	60	32	those	those	DT
cord-264699-l8db5gll	60	33	of	of	IN
cord-264699-l8db5gll	60	34	PTH	PTH	NNP
cord-264699-l8db5gll	60	35	because	because	IN
cord-264699-l8db5gll	60	36	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	60	37	binds	bind	VBZ
cord-264699-l8db5gll	60	38	to	to	IN
cord-264699-l8db5gll	60	39	the	the	DT
cord-264699-l8db5gll	60	40	PTH	PTH	NNP
cord-264699-l8db5gll	60	41	receptor	receptor	NN
cord-264699-l8db5gll	60	42	and	and	CC
cord-264699-l8db5gll	60	43	stimulates	stimulate	VBZ
cord-264699-l8db5gll	60	44	downstream	downstream	JJ
cord-264699-l8db5gll	60	45	cellular	cellular	JJ
cord-264699-l8db5gll	60	46	events	event	NNS
cord-264699-l8db5gll	60	47	[	[	-LRB-
cord-264699-l8db5gll	60	48	18	18	CD
cord-264699-l8db5gll	60	49	]	]	-RRB-
cord-264699-l8db5gll	60	50	.	.	.
cord-264699-l8db5gll	61	1	Hence	hence	RB
cord-264699-l8db5gll	61	2	,	,	,
cord-264699-l8db5gll	61	3	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	61	4	,	,	,
cord-264699-l8db5gll	61	5	like	like	IN
cord-264699-l8db5gll	61	6	PTH	PTH	NNP
cord-264699-l8db5gll	61	7	,	,	,
cord-264699-l8db5gll	61	8	increases	increase	VBZ
cord-264699-l8db5gll	61	9	serum	serum	NN
cord-264699-l8db5gll	62	1	Ca	ca	NN
cord-264699-l8db5gll	62	2	2	2	CD
cord-264699-l8db5gll	62	3	+	+	CC
cord-264699-l8db5gll	62	4	concentrations	concentration	NNS
cord-264699-l8db5gll	62	5	by	by	IN
cord-264699-l8db5gll	62	6	stimulating	stimulate	VBG
cord-264699-l8db5gll	62	7	bone	bone	NN
cord-264699-l8db5gll	62	8	turnover	turnover	NN
cord-264699-l8db5gll	62	9	and	and	CC
cord-264699-l8db5gll	62	10	enhancing	enhance	VBG
cord-264699-l8db5gll	63	1	Ca	ca	NN
cord-264699-l8db5gll	63	2	2	2	CD
cord-264699-l8db5gll	63	3	+	+	CC
cord-264699-l8db5gll	63	4	absorption	absorption	NN
cord-264699-l8db5gll	63	5	from	from	IN
cord-264699-l8db5gll	63	6	the	the	DT
cord-264699-l8db5gll	63	7	kidney	kidney	NN
cord-264699-l8db5gll	63	8	and	and	CC
cord-264699-l8db5gll	63	9	the	the	DT
cord-264699-l8db5gll	63	10	gut	gut	NN
cord-264699-l8db5gll	63	11	[	[	-LRB-
cord-264699-l8db5gll	63	12	18	18	CD
cord-264699-l8db5gll	63	13	]	]	-RRB-
cord-264699-l8db5gll	63	14	.	.	.
cord-264699-l8db5gll	64	1	Accumulating	accumulate	VBG
cord-264699-l8db5gll	64	2	evidence	evidence	NN
cord-264699-l8db5gll	64	3	indicates	indicate	VBZ
cord-264699-l8db5gll	64	4	that	that	IN
cord-264699-l8db5gll	64	5	the	the	DT
cord-264699-l8db5gll	64	6	HTLV-1-encoded	HTLV-1-encoded	NNP
cord-264699-l8db5gll	64	7	Tax	Tax	NNP
cord-264699-l8db5gll	64	8	protein	protein	NN
cord-264699-l8db5gll	64	9	stimulates	stimulate	VBZ
cord-264699-l8db5gll	64	10	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	64	11	synthesis	synthesis	NN
cord-264699-l8db5gll	64	12	in	in	IN
cord-264699-l8db5gll	64	13	HTLV-1-infected	htlv-1-infecte	VBN
cord-264699-l8db5gll	64	14	lymphocytes	lymphocyte	NNS
cord-264699-l8db5gll	64	15	by	by	IN
cord-264699-l8db5gll	64	16	activating	activate	VBG
cord-264699-l8db5gll	64	17	the	the	DT
cord-264699-l8db5gll	64	18	PTHrP	pthrp	CD
cord-264699-l8db5gll	64	19	promoter	promoter	NN
cord-264699-l8db5gll	64	20	[	[	-LRB-
cord-264699-l8db5gll	64	21	11	11	CD
cord-264699-l8db5gll	64	22	]	]	-RRB-
cord-264699-l8db5gll	64	23	.	.	.
cord-264699-l8db5gll	65	1	Tax	tax	NN
cord-264699-l8db5gll	65	2	is	be	VBZ
cord-264699-l8db5gll	65	3	a	a	DT
cord-264699-l8db5gll	65	4	nuclear	nuclear	JJ
cord-264699-l8db5gll	65	5	phosphoprotein	phosphoprotein	NN
cord-264699-l8db5gll	65	6	of	of	IN
cord-264699-l8db5gll	65	7	either	either	DT
cord-264699-l8db5gll	65	8	37	37	CD
cord-264699-l8db5gll	65	9	or	or	CC
cord-264699-l8db5gll	65	10	40	40	CD
cord-264699-l8db5gll	65	11	kDa	kDa	NNS
cord-264699-l8db5gll	65	12	that	that	WDT
cord-264699-l8db5gll	65	13	is	be	VBZ
cord-264699-l8db5gll	65	14	required	require	VBN
cord-264699-l8db5gll	65	15	for	for	IN
cord-264699-l8db5gll	65	16	transactivation	transactivation	NN
cord-264699-l8db5gll	65	17	of	of	IN
cord-264699-l8db5gll	65	18	the	the	DT
cord-264699-l8db5gll	65	19	HTLV-1	HTLV-1	NNP
cord-264699-l8db5gll	65	20	LTR	LTR	NNP
cord-264699-l8db5gll	65	21	and	and	CC
cord-264699-l8db5gll	65	22	the	the	DT
cord-264699-l8db5gll	65	23	transformation	transformation	NN
cord-264699-l8db5gll	65	24	of	of	IN
cord-264699-l8db5gll	65	25	T	t	NN
cord-264699-l8db5gll	65	26	cells	cell	NNS
cord-264699-l8db5gll	65	27	[	[	-LRB-
cord-264699-l8db5gll	65	28	19	19	CD
cord-264699-l8db5gll	65	29	]	]	-RRB-
cord-264699-l8db5gll	65	30	.	.	.
cord-264699-l8db5gll	66	1	Tax	tax	NN
cord-264699-l8db5gll	66	2	does	do	VBZ
cord-264699-l8db5gll	66	3	not	not	RB
cord-264699-l8db5gll	66	4	bind	bind	VB
cord-264699-l8db5gll	66	5	DNA	dna	NN
cord-264699-l8db5gll	66	6	directly	directly	RB
cord-264699-l8db5gll	66	7	but	but	CC
cord-264699-l8db5gll	66	8	transactivates	transactivate	VBZ
cord-264699-l8db5gll	66	9	numerous	numerous	JJ
cord-264699-l8db5gll	66	10	cellular	cellular	JJ
cord-264699-l8db5gll	66	11	genes	gene	NNS
cord-264699-l8db5gll	66	12	by	by	IN
cord-264699-l8db5gll	66	13	interacting	interact	VBG
cord-264699-l8db5gll	66	14	physically	physically	RB
cord-264699-l8db5gll	66	15	with	with	IN
cord-264699-l8db5gll	66	16	host	host	NN
cord-264699-l8db5gll	66	17	transcription	transcription	NN
cord-264699-l8db5gll	66	18	factors	factor	NNS
cord-264699-l8db5gll	66	19	[	[	-LRB-
cord-264699-l8db5gll	66	20	19	19	CD
cord-264699-l8db5gll	66	21	]	]	-RRB-
cord-264699-l8db5gll	66	22	.	.	.
cord-264699-l8db5gll	67	1	Tax	tax	NN
cord-264699-l8db5gll	67	2	appears	appear	VBZ
cord-264699-l8db5gll	67	3	to	to	TO
cord-264699-l8db5gll	67	4	stimulate	stimulate	VB
cord-264699-l8db5gll	67	5	the	the	DT
cord-264699-l8db5gll	67	6	promoter	promoter	NN
cord-264699-l8db5gll	67	7	activity	activity	NN
cord-264699-l8db5gll	67	8	of	of	IN
cord-264699-l8db5gll	67	9	the	the	DT
cord-264699-l8db5gll	67	10	gene	gene	NN
cord-264699-l8db5gll	67	11	that	that	WDT
cord-264699-l8db5gll	67	12	encodes	encode	VBZ
cord-264699-l8db5gll	67	13	PTHrP	pthrp	NN
cord-264699-l8db5gll	67	14	by	by	IN
cord-264699-l8db5gll	67	15	communicating	communicate	VBG
cord-264699-l8db5gll	67	16	with	with	IN
cord-264699-l8db5gll	67	17	multiple	multiple	JJ
cord-264699-l8db5gll	67	18	transcription	transcription	NN
cord-264699-l8db5gll	67	19	factors	factor	NNS
cord-264699-l8db5gll	67	20	,	,	,
cord-264699-l8db5gll	67	21	including	include	VBG
cord-264699-l8db5gll	67	22	activator	activator	NN
cord-264699-l8db5gll	67	23	protein	protein	NN
cord-264699-l8db5gll	67	24	1	1	CD
cord-264699-l8db5gll	67	25	(	(	-LRB-
cord-264699-l8db5gll	67	26	AP1	AP1	NNP
cord-264699-l8db5gll	67	27	)	)	-RRB-
cord-264699-l8db5gll	67	28	,	,	,
cord-264699-l8db5gll	67	29	AP2	AP2	NNP
cord-264699-l8db5gll	67	30	,	,	,
cord-264699-l8db5gll	67	31	Est1	Est1	NNP
cord-264699-l8db5gll	67	32	and	and	CC
cord-264699-l8db5gll	67	33	SP1	SP1	NNP
cord-264699-l8db5gll	67	34	[	[	-LRB-
cord-264699-l8db5gll	67	35	11	11	CD
cord-264699-l8db5gll	67	36	]	]	-RRB-
cord-264699-l8db5gll	67	37	.	.	.
cord-264699-l8db5gll	68	1	Tax	tax	NN
cord-264699-l8db5gll	68	2	forms	form	NNS
cord-264699-l8db5gll	68	3	a	a	DT
cord-264699-l8db5gll	68	4	ternary	ternary	JJ
cord-264699-l8db5gll	68	5	complex	complex	NN
cord-264699-l8db5gll	68	6	with	with	IN
cord-264699-l8db5gll	68	7	Est1	Est1	NNP
cord-264699-l8db5gll	68	8	and	and	CC
cord-264699-l8db5gll	68	9	SP1	SP1	NNP
cord-264699-l8db5gll	68	10	,	,	,
cord-264699-l8db5gll	68	11	and	and	CC
cord-264699-l8db5gll	68	12	their	-PRON-	PRP$
cord-264699-l8db5gll	68	13	binding	binding	NN
cord-264699-l8db5gll	68	14	to	to	IN
cord-264699-l8db5gll	68	15	the	the	DT
cord-264699-l8db5gll	68	16	PTHrP	pthrp	CD
cord-264699-l8db5gll	68	17	promoter	promoter	NN
cord-264699-l8db5gll	68	18	strongly	strongly	RB
cord-264699-l8db5gll	68	19	stimulates	stimulate	VBZ
cord-264699-l8db5gll	68	20	its	-PRON-	PRP$
cord-264699-l8db5gll	68	21	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	68	22	activity	activity	NN
cord-264699-l8db5gll	68	23	[	[	-LRB-
cord-264699-l8db5gll	68	24	20	20	CD
cord-264699-l8db5gll	68	25	]	]	-RRB-
cord-264699-l8db5gll	68	26	.	.	.
cord-264699-l8db5gll	69	1	Aggravated	aggravated	JJ
cord-264699-l8db5gll	69	2	hypercalcemia	hypercalcemia	NN
cord-264699-l8db5gll	69	3	,	,	,
cord-264699-l8db5gll	69	4	however	however	RB
cord-264699-l8db5gll	69	5	,	,	,
cord-264699-l8db5gll	69	6	is	be	VBZ
cord-264699-l8db5gll	69	7	observed	observe	VBN
cord-264699-l8db5gll	69	8	most	most	RBS
cord-264699-l8db5gll	69	9	often	often	RB
cord-264699-l8db5gll	69	10	in	in	IN
cord-264699-l8db5gll	69	11	end	end	NN
cord-264699-l8db5gll	69	12	-	-	HYPH
cord-264699-l8db5gll	69	13	stage	stage	NN
cord-264699-l8db5gll	69	14	ATL	ATL	NNP
cord-264699-l8db5gll	69	15	when	when	WRB
cord-264699-l8db5gll	69	16	Tax	tax	NN
cord-264699-l8db5gll	69	17	expression	expression	NN
cord-264699-l8db5gll	69	18	is	be	VBZ
cord-264699-l8db5gll	69	19	relatively	relatively	RB
cord-264699-l8db5gll	69	20	low	low	JJ
cord-264699-l8db5gll	69	21	[	[	-LRB-
cord-264699-l8db5gll	69	22	11	11	CD
cord-264699-l8db5gll	69	23	]	]	-RRB-
cord-264699-l8db5gll	69	24	.	.	.
cord-264699-l8db5gll	70	1	Mice	mouse	NNS
cord-264699-l8db5gll	70	2	infected	infect	VBN
cord-264699-l8db5gll	70	3	experimentally	experimentally	RB
cord-264699-l8db5gll	70	4	with	with	IN
cord-264699-l8db5gll	70	5	Tax	tax	NN
cord-264699-l8db5gll	70	6	-	-	HYPH
cord-264699-l8db5gll	70	7	defective	defective	JJ
cord-264699-l8db5gll	70	8	HTLV-1	HTLV-1	NNS
cord-264699-l8db5gll	70	9	have	have	VBP
cord-264699-l8db5gll	70	10	high	high	JJ
cord-264699-l8db5gll	70	11	levels	level	NNS
cord-264699-l8db5gll	70	12	of	of	IN
cord-264699-l8db5gll	70	13	PTHrP	pthrp	NN
cord-264699-l8db5gll	70	14	and	and	CC
cord-264699-l8db5gll	70	15	develop	develop	VB
cord-264699-l8db5gll	70	16	hypercalcemia	hypercalcemia	NN
cord-264699-l8db5gll	70	17	[	[	-LRB-
cord-264699-l8db5gll	70	18	21	21	CD
cord-264699-l8db5gll	70	19	]	]	-RRB-
cord-264699-l8db5gll	70	20	.	.	.
cord-264699-l8db5gll	71	1	Thus	thus	RB
cord-264699-l8db5gll	71	2	,	,	,
cord-264699-l8db5gll	71	3	as	as	IN
cord-264699-l8db5gll	71	4	yet	yet	RB
cord-264699-l8db5gll	71	5	unknown	unknown	JJ
cord-264699-l8db5gll	71	6	viral	viral	JJ
cord-264699-l8db5gll	71	7	factors	factor	NNS
cord-264699-l8db5gll	71	8	appear	appear	VBP
cord-264699-l8db5gll	71	9	to	to	TO
cord-264699-l8db5gll	71	10	contribute	contribute	VB
cord-264699-l8db5gll	71	11	to	to	IN
cord-264699-l8db5gll	71	12	the	the	DT
cord-264699-l8db5gll	71	13	development	development	NN
cord-264699-l8db5gll	71	14	of	of	IN
cord-264699-l8db5gll	71	15	HTLV-1-associated	htlv-1-associate	VBN
cord-264699-l8db5gll	71	16	hypercalcemia	hypercalcemia	NN
cord-264699-l8db5gll	71	17	in	in	IN
cord-264699-l8db5gll	71	18	addition	addition	NN
cord-264699-l8db5gll	71	19	to	to	IN
cord-264699-l8db5gll	71	20	Tax	tax	NN
cord-264699-l8db5gll	71	21	.	.	.
cord-264699-l8db5gll	72	1	Alteration	alteration	NN
cord-264699-l8db5gll	72	2	of	of	IN
cord-264699-l8db5gll	72	3	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	72	4	and	and	CC
cord-264699-l8db5gll	72	5	insulin	insulin	NN
cord-264699-l8db5gll	72	6	sensitivity	sensitivity	NN
cord-264699-l8db5gll	72	7	in	in	IN
cord-264699-l8db5gll	72	8	HIV-1-infection	hiv-1-infection	NN
cord-264699-l8db5gll	72	9	:	:	:
cord-264699-l8db5gll	72	10	implications	implication	NNS
cord-264699-l8db5gll	72	11	for	for	IN
cord-264699-l8db5gll	72	12	AIDS	AIDS	NNP
cord-264699-l8db5gll	72	13	-	-	HYPH
cord-264699-l8db5gll	72	14	related	relate	VBN
cord-264699-l8db5gll	72	15	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	72	16	and	and	CC
cord-264699-l8db5gll	72	17	insulin	insulin	NN
cord-264699-l8db5gll	72	18	-	-	HYPH
cord-264699-l8db5gll	72	19	resistance	resistance	NN
cord-264699-l8db5gll	72	20	syndrome	syndrome	NN
cord-264699-l8db5gll	72	21	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	72	22	infection	infection	NN
cord-264699-l8db5gll	72	23	is	be	VBZ
cord-264699-l8db5gll	72	24	associated	associate	VBN
cord-264699-l8db5gll	72	25	with	with	IN
cord-264699-l8db5gll	72	26	profound	profound	JJ
cord-264699-l8db5gll	72	27	immunosuppression	immunosuppression	NN
cord-264699-l8db5gll	72	28	,	,	,
cord-264699-l8db5gll	72	29	muscle	muscle	NN
cord-264699-l8db5gll	72	30	wasting	wasting	NN
cord-264699-l8db5gll	72	31	and	and	CC
cord-264699-l8db5gll	72	32	,	,	,
cord-264699-l8db5gll	72	33	occasionally	occasionally	RB
cord-264699-l8db5gll	72	34	,	,	,
cord-264699-l8db5gll	72	35	the	the	DT
cord-264699-l8db5gll	72	36	AIDS	AIDS	NNP
cord-264699-l8db5gll	72	37	-	-	HYPH
cord-264699-l8db5gll	72	38	related	relate	VBN
cord-264699-l8db5gll	72	39	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	72	40	and	and	CC
cord-264699-l8db5gll	72	41	insulin	insulin	NN
cord-264699-l8db5gll	72	42	-	-	HYPH
cord-264699-l8db5gll	72	43	resistance	resistance	NN
cord-264699-l8db5gll	72	44	syndrome	syndrome	NN
cord-264699-l8db5gll	72	45	.	.	.
cord-264699-l8db5gll	73	1	The	the	DT
cord-264699-l8db5gll	73	2	latter	latter	JJ
cord-264699-l8db5gll	73	3	is	be	VBZ
cord-264699-l8db5gll	73	4	characterized	characterize	VBN
cord-264699-l8db5gll	73	5	by	by	IN
cord-264699-l8db5gll	73	6	a	a	DT
cord-264699-l8db5gll	73	7	sometimes	sometimes	RB
cord-264699-l8db5gll	73	8	striking	striking	JJ
cord-264699-l8db5gll	73	9	phenotype	phenotype	NN
cord-264699-l8db5gll	73	10	and	and	CC
cord-264699-l8db5gll	73	11	marked	mark	VBD
cord-264699-l8db5gll	73	12	metabolic	metabolic	JJ
cord-264699-l8db5gll	73	13	disturbances	disturbance	NNS
cord-264699-l8db5gll	73	14	,	,	,
cord-264699-l8db5gll	73	15	especially	especially	RB
cord-264699-l8db5gll	73	16	after	after	IN
cord-264699-l8db5gll	73	17	addition	addition	NN
cord-264699-l8db5gll	73	18	of	of	IN
cord-264699-l8db5gll	73	19	potent	potent	JJ
cord-264699-l8db5gll	73	20	anti	anti	JJ
cord-264699-l8db5gll	73	21	-	-	JJ
cord-264699-l8db5gll	73	22	HIV-1	hiv-1	JJ
cord-264699-l8db5gll	73	23	treatment	treatment	NN
cord-264699-l8db5gll	73	24	regimens	regimen	NNS
cord-264699-l8db5gll	73	25	,	,	,
cord-264699-l8db5gll	73	26	which	which	WDT
cord-264699-l8db5gll	73	27	have	have	VBP
cord-264699-l8db5gll	73	28	significantly	significantly	RB
cord-264699-l8db5gll	73	29	improved	improve	VBN
cord-264699-l8db5gll	73	30	patients	patient	NNS
cord-264699-l8db5gll	73	31	'	'	POS
cord-264699-l8db5gll	73	32	life	life	NN
cord-264699-l8db5gll	73	33	expectancy	expectancy	NN
cord-264699-l8db5gll	73	34	and	and	CC
cord-264699-l8db5gll	73	35	allowed	allow	VBD
cord-264699-l8db5gll	73	36	sufficient	sufficient	JJ
cord-264699-l8db5gll	73	37	time	time	NN
cord-264699-l8db5gll	73	38	for	for	IN
cord-264699-l8db5gll	73	39	the	the	DT
cord-264699-l8db5gll	73	40	syndrome	syndrome	NN
cord-264699-l8db5gll	73	41	to	to	TO
cord-264699-l8db5gll	73	42	develop	develop	VB
cord-264699-l8db5gll	73	43	[	[	-LRB-
cord-264699-l8db5gll	73	44	10	10	CD
cord-264699-l8db5gll	73	45	]	]	-RRB-
cord-264699-l8db5gll	73	46	.	.	.
cord-264699-l8db5gll	74	1	Patients	patient	NNS
cord-264699-l8db5gll	74	2	with	with	IN
cord-264699-l8db5gll	74	3	this	this	DT
cord-264699-l8db5gll	74	4	syndrome	syndrome	NN
cord-264699-l8db5gll	74	5	have	have	VBP
cord-264699-l8db5gll	74	6	a	a	DT
cord-264699-l8db5gll	74	7	combination	combination	NN
cord-264699-l8db5gll	74	8	of	of	IN
cord-264699-l8db5gll	74	9	regional	regional	JJ
cord-264699-l8db5gll	74	10	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	74	11	and	and	CC
cord-264699-l8db5gll	74	12	characteristic	characteristic	JJ
cord-264699-l8db5gll	74	13	redistribution	redistribution	NN
cord-264699-l8db5gll	74	14	of	of	IN
cord-264699-l8db5gll	74	15	adipose	adipose	JJ
cord-264699-l8db5gll	74	16	tissue	tissue	NN
cord-264699-l8db5gll	74	17	with	with	IN
cord-264699-l8db5gll	74	18	accumulation	accumulation	NN
cord-264699-l8db5gll	74	19	of	of	IN
cord-264699-l8db5gll	74	20	visceral	visceral	JJ
cord-264699-l8db5gll	74	21	,	,	,
cord-264699-l8db5gll	74	22	breast	breast	NN
cord-264699-l8db5gll	74	23	and	and	CC
cord-264699-l8db5gll	74	24	nuchal	nuchal	JJ
cord-264699-l8db5gll	74	25	fat	fat	NN
cord-264699-l8db5gll	74	26	and	and	CC
cord-264699-l8db5gll	74	27	loss	loss	NN
cord-264699-l8db5gll	74	28	of	of	IN
cord-264699-l8db5gll	74	29	subcutaneous	subcutaneous	JJ
cord-264699-l8db5gll	74	30	fat	fat	NN
cord-264699-l8db5gll	74	31	[	[	-LRB-
cord-264699-l8db5gll	74	32	10	10	CD
cord-264699-l8db5gll	74	33	,	,	,
cord-264699-l8db5gll	74	34	22	22	CD
cord-264699-l8db5gll	74	35	]	]	-RRB-
cord-264699-l8db5gll	74	36	.	.	.
cord-264699-l8db5gll	75	1	The	the	DT
cord-264699-l8db5gll	75	2	AIDS	AIDS	NNP
cord-264699-l8db5gll	75	3	-	-	HYPH
cord-264699-l8db5gll	75	4	related	relate	VBN
cord-264699-l8db5gll	75	5	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	75	6	and	and	CC
cord-264699-l8db5gll	75	7	insulin	insulin	NN
cord-264699-l8db5gll	75	8	-	-	HYPH
cord-264699-l8db5gll	75	9	resistance	resistance	NN
cord-264699-l8db5gll	75	10	syndrome	syndrome	NN
cord-264699-l8db5gll	75	11	is	be	VBZ
cord-264699-l8db5gll	75	12	accompanied	accompany	VBN
cord-264699-l8db5gll	75	13	by	by	IN
cord-264699-l8db5gll	75	14	profound	profound	JJ
cord-264699-l8db5gll	75	15	dyslipidemia	dyslipidemia	NN
cord-264699-l8db5gll	75	16	and	and	CC
cord-264699-l8db5gll	75	17	either	either	CC
cord-264699-l8db5gll	75	18	carbohydrate	carbohydrate	NN
cord-264699-l8db5gll	75	19	intolerance	intolerance	NN
cord-264699-l8db5gll	75	20	or	or	CC
cord-264699-l8db5gll	75	21	overt	overt	JJ
cord-264699-l8db5gll	75	22	diabetes	diabetes	NN
cord-264699-l8db5gll	75	23	mellitus	mellitus	NN
cord-264699-l8db5gll	75	24	[	[	-LRB-
cord-264699-l8db5gll	75	25	10	10	CD
cord-264699-l8db5gll	75	26	]	]	-RRB-
cord-264699-l8db5gll	75	27	.	.	.
cord-264699-l8db5gll	76	1	As	as	IN
cord-264699-l8db5gll	76	2	the	the	DT
cord-264699-l8db5gll	76	3	phenotypic	phenotypic	NN
cord-264699-l8db5gll	76	4	and	and	CC
cord-264699-l8db5gll	76	5	metabolic	metabolic	JJ
cord-264699-l8db5gll	76	6	manifestations	manifestation	NNS
cord-264699-l8db5gll	76	7	of	of	IN
cord-264699-l8db5gll	76	8	the	the	DT
cord-264699-l8db5gll	76	9	AIDS	AIDS	NNP
cord-264699-l8db5gll	76	10	-	-	HYPH
cord-264699-l8db5gll	76	11	related	relate	VBN
cord-264699-l8db5gll	76	12	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	76	13	and	and	CC
cord-264699-l8db5gll	76	14	insulin	insulin	NN
cord-264699-l8db5gll	76	15	-	-	HYPH
cord-264699-l8db5gll	76	16	resistance	resistance	NN
cord-264699-l8db5gll	76	17	syndrome	syndrome	NN
cord-264699-l8db5gll	76	18	are	be	VBP
cord-264699-l8db5gll	76	19	reminiscent	reminiscent	JJ
cord-264699-l8db5gll	76	20	of	of	IN
cord-264699-l8db5gll	76	21	the	the	DT
cord-264699-l8db5gll	76	22	typical	typical	JJ
cord-264699-l8db5gll	76	23	phenotype	phenotype	NN
cord-264699-l8db5gll	76	24	of	of	IN
cord-264699-l8db5gll	76	25	chronic	chronic	JJ
cord-264699-l8db5gll	76	26	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	76	27	excess	excess	NN
cord-264699-l8db5gll	76	28	or	or	CC
cord-264699-l8db5gll	76	29	Cushing	Cushing	NNP
cord-264699-l8db5gll	76	30	syndrome	syndrome	NN
cord-264699-l8db5gll	76	31	,	,	,
cord-264699-l8db5gll	76	32	this	this	DT
cord-264699-l8db5gll	76	33	syndrome	syndrome	NN
cord-264699-l8db5gll	76	34	was	be	VBD
cord-264699-l8db5gll	76	35	referred	refer	VBN
cord-264699-l8db5gll	76	36	to	to	IN
cord-264699-l8db5gll	76	37	initially	initially	RB
cord-264699-l8db5gll	76	38	as	as	IN
cord-264699-l8db5gll	76	39	a	a	DT
cord-264699-l8db5gll	76	40	Pseudo	Pseudo	NNP
cord-264699-l8db5gll	76	41	-	-	HYPH
cord-264699-l8db5gll	76	42	Cushing	Cushing	NNP
cord-264699-l8db5gll	76	43	state	state	NN
cord-264699-l8db5gll	76	44	[	[	-LRB-
cord-264699-l8db5gll	76	45	10	10	CD
cord-264699-l8db5gll	76	46	]	]	-RRB-
cord-264699-l8db5gll	76	47	.	.	.
cord-264699-l8db5gll	77	1	Anti	Anti	NNP
cord-264699-l8db5gll	77	2	-	-	NNP
cord-264699-l8db5gll	77	3	HIV-1	hiv-1	JJ
cord-264699-l8db5gll	77	4	drugs	drug	NNS
cord-264699-l8db5gll	77	5	,	,	,
cord-264699-l8db5gll	77	6	such	such	JJ
cord-264699-l8db5gll	77	7	as	as	IN
cord-264699-l8db5gll	77	8	nucleotide	nucleotide	JJ
cord-264699-l8db5gll	77	9	reverse	reverse	NN
cord-264699-l8db5gll	77	10	transcriptase	transcriptase	NN
cord-264699-l8db5gll	77	11	and	and	CC
cord-264699-l8db5gll	77	12	protease	protease	NN
cord-264699-l8db5gll	77	13	inhibitors	inhibitor	NNS
cord-264699-l8db5gll	77	14	,	,	,
cord-264699-l8db5gll	77	15	appear	appear	VBP
cord-264699-l8db5gll	77	16	to	to	TO
cord-264699-l8db5gll	77	17	contribute	contribute	VB
cord-264699-l8db5gll	77	18	to	to	IN
cord-264699-l8db5gll	77	19	the	the	DT
cord-264699-l8db5gll	77	20	development	development	NN
cord-264699-l8db5gll	77	21	of	of	IN
cord-264699-l8db5gll	77	22	this	this	DT
cord-264699-l8db5gll	77	23	syndrome	syndrome	NN
cord-264699-l8db5gll	77	24	,	,	,
cord-264699-l8db5gll	77	25	based	base	VBN
cord-264699-l8db5gll	77	26	on	on	IN
cord-264699-l8db5gll	77	27	the	the	DT
cord-264699-l8db5gll	77	28	evidence	evidence	NN
cord-264699-l8db5gll	77	29	that	that	IN
cord-264699-l8db5gll	77	30	the	the	DT
cord-264699-l8db5gll	77	31	majority	majority	NN
cord-264699-l8db5gll	77	32	of	of	IN
cord-264699-l8db5gll	77	33	AIDS	AIDS	NNP
cord-264699-l8db5gll	77	34	patients	patient	NNS
cord-264699-l8db5gll	77	35	develop	develop	VBP
cord-264699-l8db5gll	77	36	this	this	DT
cord-264699-l8db5gll	77	37	syndrome	syndrome	NN
cord-264699-l8db5gll	77	38	after	after	IN
cord-264699-l8db5gll	77	39	taking	take	VBG
cord-264699-l8db5gll	77	40	such	such	JJ
cord-264699-l8db5gll	77	41	compounds	compound	NNS
cord-264699-l8db5gll	77	42	[	[	-LRB-
cord-264699-l8db5gll	77	43	22	22	CD
cord-264699-l8db5gll	77	44	,	,	,
cord-264699-l8db5gll	77	45	23	23	CD
cord-264699-l8db5gll	77	46	]	]	-RRB-
cord-264699-l8db5gll	77	47	.	.	.
cord-264699-l8db5gll	78	1	However	however	RB
cord-264699-l8db5gll	78	2	,	,	,
cord-264699-l8db5gll	78	3	some	some	DT
cord-264699-l8db5gll	78	4	patients	patient	NNS
cord-264699-l8db5gll	78	5	develop	develop	VBP
cord-264699-l8db5gll	78	6	the	the	DT
cord-264699-l8db5gll	78	7	characteristic	characteristic	JJ
cord-264699-l8db5gll	78	8	features	feature	NNS
cord-264699-l8db5gll	78	9	of	of	IN
cord-264699-l8db5gll	78	10	the	the	DT
cord-264699-l8db5gll	78	11	syndrome	syndrome	NN
cord-264699-l8db5gll	78	12	before	before	IN
cord-264699-l8db5gll	78	13	treatment	treatment	NN
cord-264699-l8db5gll	78	14	,	,	,
cord-264699-l8db5gll	78	15	which	which	WDT
cord-264699-l8db5gll	78	16	indicates	indicate	VBZ
cord-264699-l8db5gll	78	17	that	that	IN
cord-264699-l8db5gll	78	18	either	either	CC
cord-264699-l8db5gll	78	19	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	78	20	infection	infection	NN
cord-264699-l8db5gll	78	21	itself	-PRON-	PRP
cord-264699-l8db5gll	78	22	induces	induce	VBZ
cord-264699-l8db5gll	78	23	these	these	DT
cord-264699-l8db5gll	78	24	pathological	pathological	JJ
cord-264699-l8db5gll	78	25	changes	change	NNS
cord-264699-l8db5gll	78	26	or	or	CC
cord-264699-l8db5gll	78	27	that	that	IN
cord-264699-l8db5gll	78	28	it	-PRON-	PRP
cord-264699-l8db5gll	78	29	increases	increase	VBZ
cord-264699-l8db5gll	78	30	the	the	DT
cord-264699-l8db5gll	78	31	vulnerability	vulnerability	NN
cord-264699-l8db5gll	78	32	of	of	IN
cord-264699-l8db5gll	78	33	patients	patient	NNS
cord-264699-l8db5gll	78	34	to	to	IN
cord-264699-l8db5gll	78	35	the	the	DT
cord-264699-l8db5gll	78	36	facilitation	facilitation	NN
cord-264699-l8db5gll	78	37	of	of	IN
cord-264699-l8db5gll	78	38	expression	expression	NN
cord-264699-l8db5gll	78	39	of	of	IN
cord-264699-l8db5gll	78	40	this	this	DT
cord-264699-l8db5gll	78	41	syndrome	syndrome	NN
cord-264699-l8db5gll	78	42	by	by	IN
cord-264699-l8db5gll	78	43	anti	anti	JJ
cord-264699-l8db5gll	78	44	-	-	JJ
cord-264699-l8db5gll	78	45	viral	viral	JJ
cord-264699-l8db5gll	78	46	drugs	drug	NNS
cord-264699-l8db5gll	78	47	[	[	-LRB-
cord-264699-l8db5gll	78	48	24	24	CD
cord-264699-l8db5gll	78	49	,	,	,
cord-264699-l8db5gll	78	50	25	25	CD
cord-264699-l8db5gll	78	51	]	]	-RRB-
cord-264699-l8db5gll	78	52	.	.	.
cord-264699-l8db5gll	79	1	In	in	IN
cord-264699-l8db5gll	79	2	this	this	DT
cord-264699-l8db5gll	79	3	context	context	NN
cord-264699-l8db5gll	79	4	,	,	,
cord-264699-l8db5gll	79	5	anti	anti	JJ
cord-264699-l8db5gll	79	6	-	-	JJ
cord-264699-l8db5gll	79	7	HIV-1	hiv-1	JJ
cord-264699-l8db5gll	79	8	drugs	drug	NNS
cord-264699-l8db5gll	79	9	might	may	MD
cord-264699-l8db5gll	79	10	exacerbate	exacerbate	VB
cord-264699-l8db5gll	79	11	already	already	RB
cord-264699-l8db5gll	79	12	present	present	JJ
cord-264699-l8db5gll	79	13	,	,	,
cord-264699-l8db5gll	79	14	smoldering	smoldering	JJ
cord-264699-l8db5gll	79	15	or	or	CC
cord-264699-l8db5gll	79	16	subclinical	subclinical	JJ
cord-264699-l8db5gll	79	17	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	79	18	and	and	CC
cord-264699-l8db5gll	79	19	insulin	insulin	NN
cord-264699-l8db5gll	79	20	-	-	HYPH
cord-264699-l8db5gll	79	21	resistance	resistance	NN
cord-264699-l8db5gll	79	22	that	that	WDT
cord-264699-l8db5gll	79	23	is	be	VBZ
cord-264699-l8db5gll	79	24	masked	mask	VBN
cord-264699-l8db5gll	79	25	by	by	IN
cord-264699-l8db5gll	79	26	illness	illness	NN
cord-264699-l8db5gll	79	27	-	-	HYPH
cord-264699-l8db5gll	79	28	associated	associate	VBN
cord-264699-l8db5gll	79	29	wasting	wasting	NN
cord-264699-l8db5gll	79	30	,	,	,
cord-264699-l8db5gll	79	31	in	in	IN
cord-264699-l8db5gll	79	32	agreement	agreement	NN
cord-264699-l8db5gll	79	33	with	with	IN
cord-264699-l8db5gll	79	34	the	the	DT
cord-264699-l8db5gll	79	35	evidence	evidence	NN
cord-264699-l8db5gll	79	36	that	that	IN
cord-264699-l8db5gll	79	37	the	the	DT
cord-264699-l8db5gll	79	38	drug	drug	NN
cord-264699-l8db5gll	79	39	effects	effect	NNS
cord-264699-l8db5gll	79	40	listed	list	VBN
cord-264699-l8db5gll	79	41	above	above	RB
cord-264699-l8db5gll	79	42	do	do	VBP
cord-264699-l8db5gll	79	43	not	not	RB
cord-264699-l8db5gll	79	44	explain	explain	VB
cord-264699-l8db5gll	79	45	the	the	DT
cord-264699-l8db5gll	79	46	complete	complete	JJ
cord-264699-l8db5gll	79	47	clinical	clinical	JJ
cord-264699-l8db5gll	79	48	picture	picture	NN
cord-264699-l8db5gll	79	49	of	of	IN
cord-264699-l8db5gll	79	50	AIDS	AIDS	NNP
cord-264699-l8db5gll	79	51	-	-	HYPH
cord-264699-l8db5gll	79	52	related	relate	VBN
cord-264699-l8db5gll	79	53	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	79	54	and	and	CC
cord-264699-l8db5gll	79	55	insulin	insulin	NN
cord-264699-l8db5gll	79	56	resistance	resistance	NN
cord-264699-l8db5gll	79	57	[	[	-LRB-
cord-264699-l8db5gll	79	58	10	10	CD
cord-264699-l8db5gll	79	59	,	,	,
cord-264699-l8db5gll	79	60	26	26	CD
cord-264699-l8db5gll	79	61	]	]	-RRB-
cord-264699-l8db5gll	79	62	.	.	.
cord-264699-l8db5gll	80	1	Because	because	IN
cord-264699-l8db5gll	80	2	the	the	DT
cord-264699-l8db5gll	80	3	clinical	clinical	JJ
cord-264699-l8db5gll	80	4	picture	picture	NN
cord-264699-l8db5gll	80	5	of	of	IN
cord-264699-l8db5gll	80	6	AIDS	AIDS	NNP
cord-264699-l8db5gll	80	7	-	-	HYPH
cord-264699-l8db5gll	80	8	related	relate	VBN
cord-264699-l8db5gll	80	9	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	80	10	and	and	CC
cord-264699-l8db5gll	80	11	insulin	insulin	NN
cord-264699-l8db5gll	80	12	-	-	HYPH
cord-264699-l8db5gll	80	13	resistance	resistance	NN
cord-264699-l8db5gll	80	14	syndrome	syndrome	NN
cord-264699-l8db5gll	80	15	overlaps	overlap	VBZ
cord-264699-l8db5gll	80	16	with	with	IN
cord-264699-l8db5gll	80	17	that	that	DT
cord-264699-l8db5gll	80	18	of	of	IN
cord-264699-l8db5gll	80	19	Cushing	Cushing	NNP
cord-264699-l8db5gll	80	20	syndrome	syndrome	NN
cord-264699-l8db5gll	80	21	,	,	,
cord-264699-l8db5gll	80	22	the	the	DT
cord-264699-l8db5gll	80	23	adrenal	adrenal	JJ
cord-264699-l8db5gll	80	24	function	function	NN
cord-264699-l8db5gll	80	25	of	of	IN
cord-264699-l8db5gll	80	26	patients	patient	NNS
cord-264699-l8db5gll	80	27	with	with	IN
cord-264699-l8db5gll	80	28	these	these	DT
cord-264699-l8db5gll	80	29	syndromes	syndrome	NNS
cord-264699-l8db5gll	80	30	has	have	VBZ
cord-264699-l8db5gll	80	31	been	be	VBN
cord-264699-l8db5gll	80	32	examined	examine	VBN
cord-264699-l8db5gll	80	33	,	,	,
cord-264699-l8db5gll	80	34	however	however	RB
cord-264699-l8db5gll	80	35	,	,	,
cord-264699-l8db5gll	80	36	their	-PRON-	PRP$
cord-264699-l8db5gll	80	37	HPA	HPA	NNP
cord-264699-l8db5gll	80	38	axis	axis	NN
cord-264699-l8db5gll	80	39	is	be	VBZ
cord-264699-l8db5gll	80	40	normal	normal	JJ
cord-264699-l8db5gll	80	41	[	[	-LRB-
cord-264699-l8db5gll	80	42	27	27	CD
cord-264699-l8db5gll	80	43	]	]	-RRB-
cord-264699-l8db5gll	80	44	.	.	.
cord-264699-l8db5gll	81	1	Moreover	moreover	RB
cord-264699-l8db5gll	81	2	,	,	,
cord-264699-l8db5gll	81	3	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	81	4	receptors	receptor	NNS
cord-264699-l8db5gll	81	5	(	(	-LRB-
cord-264699-l8db5gll	81	6	GRs	GRs	NNP
cord-264699-l8db5gll	81	7	)	)	-RRB-
cord-264699-l8db5gll	81	8	are	be	VBP
cord-264699-l8db5gll	81	9	present	present	JJ
cord-264699-l8db5gll	81	10	at	at	IN
cord-264699-l8db5gll	81	11	normal	normal	JJ
cord-264699-l8db5gll	81	12	concentrations	concentration	NNS
cord-264699-l8db5gll	81	13	on	on	IN
cord-264699-l8db5gll	81	14	peripheral	peripheral	JJ
cord-264699-l8db5gll	81	15	leukocytes	leukocyte	NNS
cord-264699-l8db5gll	81	16	and	and	CC
cord-264699-l8db5gll	81	17	the	the	DT
cord-264699-l8db5gll	81	18	affinity	affinity	NN
cord-264699-l8db5gll	81	19	of	of	IN
cord-264699-l8db5gll	81	20	these	these	DT
cord-264699-l8db5gll	81	21	receptors	receptor	NNS
cord-264699-l8db5gll	81	22	for	for	IN
cord-264699-l8db5gll	81	23	dexamethasone	dexamethasone	NN
cord-264699-l8db5gll	81	24	is	be	VBZ
cord-264699-l8db5gll	81	25	similar	similar	JJ
cord-264699-l8db5gll	81	26	to	to	IN
cord-264699-l8db5gll	81	27	that	that	DT
cord-264699-l8db5gll	81	28	of	of	IN
cord-264699-l8db5gll	81	29	controls	control	NNS
cord-264699-l8db5gll	81	30	.	.	.
cord-264699-l8db5gll	82	1	Therefore	therefore	RB
cord-264699-l8db5gll	82	2	,	,	,
cord-264699-l8db5gll	82	3	biochemical	biochemical	JJ
cord-264699-l8db5gll	82	4	hypercortisolism	hypercortisolism	NN
cord-264699-l8db5gll	82	5	is	be	VBZ
cord-264699-l8db5gll	82	6	not	not	RB
cord-264699-l8db5gll	82	7	likely	likely	JJ
cord-264699-l8db5gll	82	8	to	to	TO
cord-264699-l8db5gll	82	9	be	be	VB
cord-264699-l8db5gll	82	10	a	a	DT
cord-264699-l8db5gll	82	11	major	major	JJ
cord-264699-l8db5gll	82	12	cause	cause	NN
cord-264699-l8db5gll	82	13	of	of	IN
cord-264699-l8db5gll	82	14	immunosuppression	immunosuppression	NN
cord-264699-l8db5gll	82	15	,	,	,
cord-264699-l8db5gll	82	16	muscle	muscle	NN
cord-264699-l8db5gll	82	17	wasting	wasting	NN
cord-264699-l8db5gll	82	18	and	and	CC
cord-264699-l8db5gll	82	19	AIDS	AIDS	NNP
cord-264699-l8db5gll	82	20	-	-	HYPH
cord-264699-l8db5gll	82	21	related	relate	VBN
cord-264699-l8db5gll	82	22	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	82	23	and	and	CC
cord-264699-l8db5gll	82	24	insulin	insulin	NN
cord-264699-l8db5gll	82	25	resistance	resistance	NN
cord-264699-l8db5gll	82	26	.	.	.
cord-264699-l8db5gll	83	1	Rather	rather	RB
cord-264699-l8db5gll	83	2	,	,	,
cord-264699-l8db5gll	83	3	either	either	CC
cord-264699-l8db5gll	83	4	localized	localized	JJ
cord-264699-l8db5gll	83	5	or	or	CC
cord-264699-l8db5gll	83	6	tissue	tissue	NN
cord-264699-l8db5gll	83	7	-	-	HYPH
cord-264699-l8db5gll	83	8	specific	specific	JJ
cord-264699-l8db5gll	83	9	hypersensitivity	hypersensitivity	NN
cord-264699-l8db5gll	83	10	to	to	IN
cord-264699-l8db5gll	83	11	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	83	12	might	may	MD
cord-264699-l8db5gll	83	13	be	be	VB
cord-264699-l8db5gll	83	14	involved	involve	VBN
cord-264699-l8db5gll	83	15	in	in	IN
cord-264699-l8db5gll	83	16	these	these	DT
cord-264699-l8db5gll	83	17	phenomena	phenomenon	NNS
cord-264699-l8db5gll	83	18	[	[	-LRB-
cord-264699-l8db5gll	83	19	10	10	CD
cord-264699-l8db5gll	83	20	]	]	-RRB-
cord-264699-l8db5gll	83	21	.	.	.
cord-264699-l8db5gll	84	1	Furthermore	furthermore	RB
cord-264699-l8db5gll	84	2	,	,	,
cord-264699-l8db5gll	84	3	hypersensitivity	hypersensitivity	NN
cord-264699-l8db5gll	84	4	to	to	IN
cord-264699-l8db5gll	84	5	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	84	6	might	may	MD
cord-264699-l8db5gll	84	7	explain	explain	VB
cord-264699-l8db5gll	84	8	the	the	DT
cord-264699-l8db5gll	84	9	increased	increase	VBN
cord-264699-l8db5gll	84	10	vulnerability	vulnerability	NN
cord-264699-l8db5gll	84	11	of	of	IN
cord-264699-l8db5gll	84	12	AIDS	AIDS	NNP
cord-264699-l8db5gll	84	13	patients	patient	NNS
cord-264699-l8db5gll	84	14	to	to	IN
cord-264699-l8db5gll	84	15	HHV-8	HHV-8	NNP
cord-264699-l8db5gll	84	16	infections	infection	NNS
cord-264699-l8db5gll	84	17	and	and	CC
cord-264699-l8db5gll	84	18	the	the	DT
cord-264699-l8db5gll	84	19	development	development	NN
cord-264699-l8db5gll	84	20	of	of	IN
cord-264699-l8db5gll	84	21	Kaposi	Kaposi	NNP
cord-264699-l8db5gll	84	22	sarcoma	sarcoma	NN
cord-264699-l8db5gll	84	23	[	[	-LRB-
cord-264699-l8db5gll	84	24	28	28	CD
cord-264699-l8db5gll	84	25	]	]	-RRB-
cord-264699-l8db5gll	84	26	.	.	.
cord-264699-l8db5gll	85	1	In	in	IN
cord-264699-l8db5gll	85	2	agreement	agreement	NN
cord-264699-l8db5gll	85	3	with	with	IN
cord-264699-l8db5gll	85	4	these	these	DT
cord-264699-l8db5gll	85	5	findings	finding	NNS
cord-264699-l8db5gll	85	6	,	,	,
cord-264699-l8db5gll	85	7	one	one	CD
cord-264699-l8db5gll	85	8	of	of	IN
cord-264699-l8db5gll	85	9	the	the	DT
cord-264699-l8db5gll	85	10	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	85	11	proteins	protein	NNS
cord-264699-l8db5gll	85	12	,	,	,
cord-264699-l8db5gll	85	13	Vpr	Vpr	NNP
cord-264699-l8db5gll	85	14	,	,	,
cord-264699-l8db5gll	85	15	which	which	WDT
cord-264699-l8db5gll	85	16	is	be	VBZ
cord-264699-l8db5gll	85	17	a	a	DT
cord-264699-l8db5gll	85	18	96-amino	96-amino	CD
cord-264699-l8db5gll	85	19	acid	acid	NN
cord-264699-l8db5gll	85	20	virion	virion	NN
cord-264699-l8db5gll	85	21	-	-	HYPH
cord-264699-l8db5gll	85	22	associated	associate	VBN
cord-264699-l8db5gll	85	23	accessory	accessory	NN
cord-264699-l8db5gll	85	24	protein	protein	NN
cord-264699-l8db5gll	85	25	that	that	WDT
cord-264699-l8db5gll	85	26	has	have	VBZ
cord-264699-l8db5gll	85	27	multiple	multiple	JJ
cord-264699-l8db5gll	85	28	functions	function	NNS
cord-264699-l8db5gll	85	29	(	(	-LRB-
cord-264699-l8db5gll	85	30	including	include	VBG
cord-264699-l8db5gll	85	31	influencing	influence	VBG
cord-264699-l8db5gll	85	32	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	85	33	activity	activity	NN
cord-264699-l8db5gll	85	34	and	and	CC
cord-264699-l8db5gll	85	35	arresting	arrest	VBG
cord-264699-l8db5gll	85	36	the	the	DT
cord-264699-l8db5gll	85	37	cell	cell	NN
cord-264699-l8db5gll	85	38	cycle	cycle	NN
cord-264699-l8db5gll	85	39	)	)	-RRB-
cord-264699-l8db5gll	85	40	,	,	,
cord-264699-l8db5gll	85	41	increases	increase	VBZ
cord-264699-l8db5gll	85	42	the	the	DT
cord-264699-l8db5gll	85	43	effects	effect	NNS
cord-264699-l8db5gll	85	44	of	of	IN
cord-264699-l8db5gll	85	45	GR	GR	NNP
cord-264699-l8db5gll	85	46	stimulation	stimulation	NN
cord-264699-l8db5gll	85	47	by	by	IN
cord-264699-l8db5gll	85	48	several	several	JJ
cord-264699-l8db5gll	85	49	fold	fold	NN
cord-264699-l8db5gll	85	50	,	,	,
cord-264699-l8db5gll	85	51	functioning	function	VBG
cord-264699-l8db5gll	85	52	as	as	IN
cord-264699-l8db5gll	85	53	a	a	DT
cord-264699-l8db5gll	85	54	nuclear	nuclear	JJ
cord-264699-l8db5gll	85	55	receptor	receptor	NN
cord-264699-l8db5gll	85	56	coactivator	coactivator	NN
cord-264699-l8db5gll	85	57	in	in	IN
cord-264699-l8db5gll	85	58	cooperation	cooperation	NN
cord-264699-l8db5gll	85	59	with	with	IN
cord-264699-l8db5gll	85	60	a	a	DT
cord-264699-l8db5gll	85	61	host	host	NN
cord-264699-l8db5gll	85	62	cell	cell	NN
cord-264699-l8db5gll	85	63	coactivator	coactivator	NN
cord-264699-l8db5gll	85	64	complex	complex	NN
cord-264699-l8db5gll	85	65	containing	contain	VBG
cord-264699-l8db5gll	85	66	p300	p300	NNP
cord-264699-l8db5gll	85	67	or	or	CC
cord-264699-l8db5gll	85	68	its	-PRON-	PRP$
cord-264699-l8db5gll	85	69	homolog	homolog	NN
cord-264699-l8db5gll	85	70	CREB	CREB	NNP
cord-264699-l8db5gll	85	71	-	-	HYPH
cord-264699-l8db5gll	85	72	binding	bind	VBG
cord-264699-l8db5gll	85	73	protein	protein	NN
cord-264699-l8db5gll	85	74	(	(	-LRB-
cord-264699-l8db5gll	85	75	CBP	CBP	NNP
cord-264699-l8db5gll	85	76	)	)	-RRB-
cord-264699-l8db5gll	86	1	[	[	-LRB-
cord-264699-l8db5gll	86	2	29	29	CD
cord-264699-l8db5gll	86	3	]	]	-RRB-
cord-264699-l8db5gll	87	1	[	[	-LRB-
cord-264699-l8db5gll	87	2	30	30	CD
cord-264699-l8db5gll	87	3	]	]	-RRB-
cord-264699-l8db5gll	87	4	[	[	-LRB-
cord-264699-l8db5gll	87	5	31	31	CD
cord-264699-l8db5gll	87	6	]	]	-RRB-
cord-264699-l8db5gll	88	1	[	[	-LRB-
cord-264699-l8db5gll	88	2	32	32	CD
cord-264699-l8db5gll	88	3	]	]	-RRB-
cord-264699-l8db5gll	88	4	.	.	.
cord-264699-l8db5gll	89	1	These	these	DT
cord-264699-l8db5gll	89	2	proteins	protein	NNS
cord-264699-l8db5gll	89	3	regulate	regulate	VBP
cord-264699-l8db5gll	89	4	many	many	JJ
cord-264699-l8db5gll	89	5	signal	signal	NN
cord-264699-l8db5gll	89	6	transduction	transduction	NN
cord-264699-l8db5gll	89	7	cascades	cascade	NNS
cord-264699-l8db5gll	89	8	mediated	mediate	VBN
cord-264699-l8db5gll	89	9	by	by	IN
cord-264699-l8db5gll	89	10	transcription	transcription	NN
cord-264699-l8db5gll	89	11	factors	factor	NNS
cord-264699-l8db5gll	89	12	,	,	,
cord-264699-l8db5gll	89	13	including	include	VBG
cord-264699-l8db5gll	89	14	NRs	NRs	NNP
cord-264699-l8db5gll	89	15	,	,	,
cord-264699-l8db5gll	89	16	CREbinding	crebinde	VBG
cord-264699-l8db5gll	89	17	protein	protein	NN
cord-264699-l8db5gll	89	18	(	(	-LRB-
cord-264699-l8db5gll	89	19	CREB	CREB	NNP
cord-264699-l8db5gll	89	20	)	)	-RRB-
cord-264699-l8db5gll	89	21	,	,	,
cord-264699-l8db5gll	89	22	AP-1	AP-1	NNP
cord-264699-l8db5gll	89	23	,	,	,
cord-264699-l8db5gll	89	24	nuclear	nuclear	JJ
cord-264699-l8db5gll	89	25	factor	factor	NN
cord-264699-l8db5gll	89	26	-	-	HYPH
cord-264699-l8db5gll	89	27	kB	kB	NNP
cord-264699-l8db5gll	89	28	(	(	-LRB-
cord-264699-l8db5gll	89	29	NF	nf	NN
cord-264699-l8db5gll	89	30	--	--	:
cord-264699-l8db5gll	89	31	B	b	NN
cord-264699-l8db5gll	89	32	)	)	-RRB-
cord-264699-l8db5gll	89	33	and	and	CC
cord-264699-l8db5gll	89	34	the	the	DT
cord-264699-l8db5gll	89	35	signal	signal	NN
cord-264699-l8db5gll	89	36	transducers	transducer	NNS
cord-264699-l8db5gll	89	37	and	and	CC
cord-264699-l8db5gll	89	38	activators	activator	NNS
cord-264699-l8db5gll	89	39	of	of	IN
cord-264699-l8db5gll	89	40	transcription	transcription	NN
cord-264699-l8db5gll	89	41	[	[	-LRB-
cord-264699-l8db5gll	89	42	33	33	CD
cord-264699-l8db5gll	89	43	]	]	-RRB-
cord-264699-l8db5gll	89	44	.	.	.
cord-264699-l8db5gll	90	1	p300	p300	NNP
cord-264699-l8db5gll	90	2	and	and	CC
cord-264699-l8db5gll	90	3	CBP	CBP	NNP
cord-264699-l8db5gll	90	4	have	have	VBP
cord-264699-l8db5gll	90	5	intrinsic	intrinsic	JJ
cord-264699-l8db5gll	90	6	histone	histone	NN
cord-264699-l8db5gll	90	7	acetyltransferase	acetyltransferase	NN
cord-264699-l8db5gll	90	8	activity	activity	NN
cord-264699-l8db5gll	90	9	and	and	CC
cord-264699-l8db5gll	90	10	attract	attract	VB
cord-264699-l8db5gll	90	11	other	other	JJ
cord-264699-l8db5gll	90	12	histone	histone	NN
cord-264699-l8db5gll	90	13	acetyltransferase	acetyltransferase	NN
cord-264699-l8db5gll	90	14	coactivators	coactivator	NNS
cord-264699-l8db5gll	90	15	,	,	,
cord-264699-l8db5gll	90	16	such	such	JJ
cord-264699-l8db5gll	90	17	as	as	IN
cord-264699-l8db5gll	90	18	the	the	DT
cord-264699-l8db5gll	90	19	p300	p300	NNP
cord-264699-l8db5gll	90	20	/	/	SYM
cord-264699-l8db5gll	90	21	CBP	CBP	NNP
cord-264699-l8db5gll	90	22	-	-	HYPH
cord-264699-l8db5gll	90	23	interacting	interact	VBG
cord-264699-l8db5gll	90	24	factor	factor	NN
cord-264699-l8db5gll	90	25	(	(	-LRB-
cord-264699-l8db5gll	90	26	p	p	NN
cord-264699-l8db5gll	90	27	/	/	SYM
cord-264699-l8db5gll	90	28	CAF	caf	NN
cord-264699-l8db5gll	90	29	)	)	-RRB-
cord-264699-l8db5gll	90	30	and	and	CC
cord-264699-l8db5gll	90	31	p160-type	p160-type	HYPH
cord-264699-l8db5gll	90	32	nuclear	nuclear	JJ
cord-264699-l8db5gll	90	33	receptor	receptor	NN
cord-264699-l8db5gll	90	34	coactivator	coactivator	NN
cord-264699-l8db5gll	90	35	proteins	protein	NNS
cord-264699-l8db5gll	90	36	to	to	IN
cord-264699-l8db5gll	90	37	the	the	DT
cord-264699-l8db5gll	90	38	transcription	transcription	NN
cord-264699-l8db5gll	90	39	initiation	initiation	NN
cord-264699-l8db5gll	90	40	site	site	NN
cord-264699-l8db5gll	90	41	[	[	-LRB-
cord-264699-l8db5gll	90	42	33	33	CD
cord-264699-l8db5gll	90	43	]	]	-RRB-
cord-264699-l8db5gll	90	44	.	.	.
cord-264699-l8db5gll	91	1	Thus	thus	RB
cord-264699-l8db5gll	91	2	,	,	,
cord-264699-l8db5gll	91	3	p300	p300	NNP
cord-264699-l8db5gll	91	4	/	/	SYM
cord-264699-l8db5gll	91	5	CBP	CBP	NNP
cord-264699-l8db5gll	91	6	act	act	NNP
cord-264699-l8db5gll	91	7	as	as	IN
cord-264699-l8db5gll	91	8	regulatory	regulatory	JJ
cord-264699-l8db5gll	91	9	'	'	``
cord-264699-l8db5gll	91	10	platforms	platform	NNS
cord-264699-l8db5gll	91	11	'	'	''
cord-264699-l8db5gll	91	12	for	for	IN
cord-264699-l8db5gll	91	13	the	the	DT
cord-264699-l8db5gll	91	14	transcription	transcription	NN
cord-264699-l8db5gll	91	15	of	of	IN
cord-264699-l8db5gll	91	16	numerous	numerous	JJ
cord-264699-l8db5gll	91	17	host	host	NN
cord-264699-l8db5gll	91	18	genes	gene	NNS
cord-264699-l8db5gll	91	19	,	,	,
cord-264699-l8db5gll	91	20	regulating	regulate	VBG
cord-264699-l8db5gll	91	21	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	91	22	activity	activity	NN
cord-264699-l8db5gll	91	23	of	of	IN
cord-264699-l8db5gll	91	24	many	many	JJ
cord-264699-l8db5gll	91	25	trans	trans	JJ
cord-264699-l8db5gll	91	26	-	-	JJ
cord-264699-l8db5gll	91	27	acting	acting	JJ
cord-264699-l8db5gll	91	28	factors	factor	NNS
cord-264699-l8db5gll	91	29	and	and	CC
cord-264699-l8db5gll	91	30	NRs	nrs	NN
cord-264699-l8db5gll	91	31	(	(	-LRB-
cord-264699-l8db5gll	91	32	Figure	Figure	NNP
cord-264699-l8db5gll	91	33	2	2	CD
cord-264699-l8db5gll	91	34	)	)	-RRB-
cord-264699-l8db5gll	91	35	.	.	.
cord-264699-l8db5gll	92	1	Vpr	Vpr	NNP
cord-264699-l8db5gll	92	2	contains	contain	VBZ
cord-264699-l8db5gll	92	3	a	a	DT
cord-264699-l8db5gll	92	4	NR	NR	NNP
cord-264699-l8db5gll	92	5	coactivator	coactivator	NN
cord-264699-l8db5gll	92	6	box	box	NN
cord-264699-l8db5gll	92	7	.	.	.
cord-264699-l8db5gll	93	1	This	this	DT
cord-264699-l8db5gll	93	2	is	be	VBZ
cord-264699-l8db5gll	93	3	similar	similar	JJ
cord-264699-l8db5gll	93	4	to	to	IN
cord-264699-l8db5gll	93	5	those	those	DT
cord-264699-l8db5gll	93	6	on	on	IN
cord-264699-l8db5gll	93	7	p160	p160	NN
cord-264699-l8db5gll	93	8	and	and	CC
cord-264699-l8db5gll	93	9	p300	p300	NNP
cord-264699-l8db5gll	93	10	/	/	SYM
cord-264699-l8db5gll	93	11	CBP	CBP	NNP
cord-264699-l8db5gll	93	12	NR	NR	NNP
cord-264699-l8db5gll	93	13	coactivators	coactivator	NNS
cord-264699-l8db5gll	93	14	,	,	,
cord-264699-l8db5gll	93	15	potentiating	potentiate	VBG
cord-264699-l8db5gll	93	16	the	the	DT
cord-264699-l8db5gll	93	17	effect	effect	NN
cord-264699-l8db5gll	93	18	of	of	IN
cord-264699-l8db5gll	93	19	ligandbound	ligandbound	JJ
cord-264699-l8db5gll	93	20	GR	GR	NNP
cord-264699-l8db5gll	93	21	and	and	CC
cord-264699-l8db5gll	93	22	p160	p160	NNP
cord-264699-l8db5gll	93	23	.	.	.
cord-264699-l8db5gll	94	1	Vpr	Vpr	NNP
cord-264699-l8db5gll	94	2	penetrates	penetrate	VBZ
cord-264699-l8db5gll	94	3	the	the	DT
cord-264699-l8db5gll	94	4	cell	cell	NN
cord-264699-l8db5gll	94	5	membrane	membrane	NN
cord-264699-l8db5gll	94	6	easily	easily	RB
cord-264699-l8db5gll	94	7	to	to	TO
cord-264699-l8db5gll	94	8	exert	exert	VB
cord-264699-l8db5gll	94	9	its	-PRON-	PRP$
cord-264699-l8db5gll	94	10	biological	biological	JJ
cord-264699-l8db5gll	94	11	effects	effect	NNS
cord-264699-l8db5gll	94	12	even	even	RB
cord-264699-l8db5gll	94	13	when	when	WRB
cord-264699-l8db5gll	94	14	added	add	VBN
cord-264699-l8db5gll	94	15	in	in	IN
cord-264699-l8db5gll	94	16	the	the	DT
cord-264699-l8db5gll	94	17	media	medium	NNS
cord-264699-l8db5gll	94	18	surrounding	surround	VBG
cord-264699-l8db5gll	94	19	the	the	DT
cord-264699-l8db5gll	94	20	cells	cell	NNS
cord-264699-l8db5gll	94	21	[	[	-LRB-
cord-264699-l8db5gll	94	22	34	34	CD
cord-264699-l8db5gll	94	23	]	]	-RRB-
cord-264699-l8db5gll	94	24	,	,	,
cord-264699-l8db5gll	94	25	thus	thus	RB
cord-264699-l8db5gll	94	26	,	,	,
cord-264699-l8db5gll	94	27	its	-PRON-	PRP$
cord-264699-l8db5gll	94	28	effects	effect	NNS
cord-264699-l8db5gll	94	29	might	may	MD
cord-264699-l8db5gll	94	30	extend	extend	VB
cord-264699-l8db5gll	94	31	to	to	IN
cord-264699-l8db5gll	94	32	tissues	tissue	NNS
cord-264699-l8db5gll	94	33	that	that	WDT
cord-264699-l8db5gll	94	34	are	be	VBP
cord-264699-l8db5gll	94	35	not	not	RB
cord-264699-l8db5gll	94	36	infected	infect	VBN
cord-264699-l8db5gll	94	37	with	with	IN
cord-264699-l8db5gll	94	38	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	94	39	.	.	.
cord-264699-l8db5gll	95	1	Another	another	DT
cord-264699-l8db5gll	95	2	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	95	3	accessory	accessory	NN
cord-264699-l8db5gll	95	4	protein	protein	NN
cord-264699-l8db5gll	95	5	,	,	,
cord-264699-l8db5gll	95	6	Tat	Tat	NNP
cord-264699-l8db5gll	95	7	,	,	,
cord-264699-l8db5gll	95	8	the	the	DT
cord-264699-l8db5gll	95	9	most	most	RBS
cord-264699-l8db5gll	95	10	potent	potent	JJ
cord-264699-l8db5gll	95	11	transactivator	transactivator	NN
cord-264699-l8db5gll	95	12	of	of	IN
cord-264699-l8db5gll	95	13	the	the	DT
cord-264699-l8db5gll	95	14	HIV-1-LTR	HIV-1-LTR	NNP
cord-264699-l8db5gll	95	15	,	,	,
cord-264699-l8db5gll	95	16	also	also	RB
cord-264699-l8db5gll	95	17	potentiates	potentiate	VBZ
cord-264699-l8db5gll	95	18	GR	GR	NNP
cord-264699-l8db5gll	95	19	-	-	HYPH
cord-264699-l8db5gll	95	20	induced	induce	VBN
cord-264699-l8db5gll	95	21	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	95	22	activity	activity	NN
cord-264699-l8db5gll	95	23	moderately	moderately	RB
cord-264699-l8db5gll	95	24	,	,	,
cord-264699-l8db5gll	95	25	possibly	possibly	RB
cord-264699-l8db5gll	95	26	through	through	IN
cord-264699-l8db5gll	95	27	accumulation	accumulation	NN
cord-264699-l8db5gll	95	28	of	of	IN
cord-264699-l8db5gll	95	29	the	the	DT
cord-264699-l8db5gll	95	30	positive	positive	JJ
cord-264699-l8db5gll	95	31	-	-	HYPH
cord-264699-l8db5gll	95	32	acting	act	VBG
cord-264699-l8db5gll	95	33	transcription	transcription	NN
cord-264699-l8db5gll	95	34	elongation	elongation	NN
cord-264699-l8db5gll	95	35	factor	factor	NN
cord-264699-l8db5gll	95	36	b	b	NN
cord-264699-l8db5gll	95	37	(	(	-LRB-
cord-264699-l8db5gll	95	38	pTEFb	pTEFb	NNS
cord-264699-l8db5gll	95	39	)	)	-RRB-
cord-264699-l8db5gll	95	40	complex	complex	NNP
cord-264699-l8db5gll	95	41	,	,	,
cord-264699-l8db5gll	95	42	which	which	WDT
cord-264699-l8db5gll	95	43	is	be	VBZ
cord-264699-l8db5gll	95	44	comprised	comprise	VBN
cord-264699-l8db5gll	95	45	of	of	IN
cord-264699-l8db5gll	95	46	the	the	DT
cord-264699-l8db5gll	95	47	cyclin	cyclin	NN
cord-264699-l8db5gll	95	48	-	-	HYPH
cord-264699-l8db5gll	95	49	dependent	dependent	JJ
cord-264699-l8db5gll	95	50	kinase	kinase	NN
cord-264699-l8db5gll	95	51	9	9	CD
cord-264699-l8db5gll	95	52	and	and	CC
cord-264699-l8db5gll	95	53	its	-PRON-	PRP$
cord-264699-l8db5gll	95	54	partner	partner	NN
cord-264699-l8db5gll	95	55	molecule	molecule	NN
cord-264699-l8db5gll	95	56	cyclin	cyclin	NN
cord-264699-l8db5gll	95	57	T	T	NNP
cord-264699-l8db5gll	95	58	,	,	,
cord-264699-l8db5gll	95	59	on	on	IN
cord-264699-l8db5gll	95	60	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	95	61	-	-	HYPH
cord-264699-l8db5gll	95	62	responsive	responsive	JJ
cord-264699-l8db5gll	95	63	promoters	promoter	NNS
cord-264699-l8db5gll	95	64	[	[	-LRB-
cord-264699-l8db5gll	95	65	35	35	CD
cord-264699-l8db5gll	95	66	]	]	-RRB-
cord-264699-l8db5gll	95	67	.	.	.
cord-264699-l8db5gll	96	1	Because	because	IN
cord-264699-l8db5gll	96	2	Tat	Tat	NNP
cord-264699-l8db5gll	96	3	,	,	,
cord-264699-l8db5gll	96	4	like	like	IN
cord-264699-l8db5gll	96	5	Vpr	Vpr	NNP
cord-264699-l8db5gll	96	6	,	,	,
cord-264699-l8db5gll	96	7	circulates	circulate	VBZ
cord-264699-l8db5gll	96	8	in	in	IN
cord-264699-l8db5gll	96	9	blood	blood	NN
cord-264699-l8db5gll	96	10	and	and	CC
cord-264699-l8db5gll	96	11	exerts	exert	VBZ
cord-264699-l8db5gll	96	12	its	-PRON-	PRP$
cord-264699-l8db5gll	96	13	actions	action	NNS
cord-264699-l8db5gll	96	14	as	as	IN
cord-264699-l8db5gll	96	15	either	either	CC
cord-264699-l8db5gll	96	16	an	an	DT
cord-264699-l8db5gll	96	17	auto	auto	NN
cord-264699-l8db5gll	96	18	/	/	SYM
cord-264699-l8db5gll	96	19	paracrine	paracrine	NN
cord-264699-l8db5gll	96	20	or	or	CC
cord-264699-l8db5gll	96	21	an	an	DT
cord-264699-l8db5gll	96	22	endocrine	endocrine	JJ
cord-264699-l8db5gll	96	23	factor	factor	NN
cord-264699-l8db5gll	96	24	by	by	IN
cord-264699-l8db5gll	96	25	penetrating	penetrate	VBG
cord-264699-l8db5gll	96	26	the	the	DT
cord-264699-l8db5gll	96	27	cell	cell	NN
cord-264699-l8db5gll	96	28	membrane	membrane	NN
cord-264699-l8db5gll	96	29	[	[	-LRB-
cord-264699-l8db5gll	96	30	36	36	CD
cord-264699-l8db5gll	96	31	]	]	-RRB-
cord-264699-l8db5gll	96	32	,	,	,
cord-264699-l8db5gll	96	33	it	-PRON-	PRP
cord-264699-l8db5gll	96	34	is	be	VBZ
cord-264699-l8db5gll	96	35	possible	possible	JJ
cord-264699-l8db5gll	96	36	that	that	IN
cord-264699-l8db5gll	96	37	Tat	Tat	NNP
cord-264699-l8db5gll	96	38	modulates	modulate	VBZ
cord-264699-l8db5gll	96	39	tissue	tissue	NN
cord-264699-l8db5gll	96	40	sensitivity	sensitivity	NN
cord-264699-l8db5gll	96	41	to	to	IN
cord-264699-l8db5gll	96	42	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	96	43	irrespective	irrespective	RB
cord-264699-l8db5gll	96	44	of	of	IN
cord-264699-l8db5gll	96	45	whether	whether	IN
cord-264699-l8db5gll	96	46	a	a	DT
cord-264699-l8db5gll	96	47	cell	cell	NN
cord-264699-l8db5gll	96	48	is	be	VBZ
cord-264699-l8db5gll	96	49	infected	infect	VBN
cord-264699-l8db5gll	96	50	with	with	IN
cord-264699-l8db5gll	96	51	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	96	52	.	.	.
cord-264699-l8db5gll	97	1	Concomitantly	concomitantly	RB
cord-264699-l8db5gll	97	2	with	with	IN
cord-264699-l8db5gll	97	3	Vpr	Vpr	NNP
cord-264699-l8db5gll	97	4	,	,	,
cord-264699-l8db5gll	97	5	Tat	Tat	NNP
cord-264699-l8db5gll	97	6	might	may	MD
cord-264699-l8db5gll	97	7	induce	induce	VB
cord-264699-l8db5gll	97	8	tissue	tissue	NN
cord-264699-l8db5gll	97	9	hypersensitivity	hypersensitivity	NN
cord-264699-l8db5gll	97	10	to	to	IN
cord-264699-l8db5gll	97	11	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	97	12	that	that	WDT
cord-264699-l8db5gll	97	13	might	may	MD
cord-264699-l8db5gll	97	14	contribute	contribute	VB
cord-264699-l8db5gll	97	15	to	to	IN
cord-264699-l8db5gll	97	16	viral	viral	JJ
cord-264699-l8db5gll	97	17	proliferation	proliferation	NN
cord-264699-l8db5gll	97	18	indirectly	indirectly	RB
cord-264699-l8db5gll	97	19	,	,	,
cord-264699-l8db5gll	97	20	by	by	IN
cord-264699-l8db5gll	97	21	suppressing	suppress	VBG
cord-264699-l8db5gll	97	22	activity	activity	NN
cord-264699-l8db5gll	97	23	of	of	IN
cord-264699-l8db5gll	97	24	the	the	DT
cord-264699-l8db5gll	97	25	host	host	NN
cord-264699-l8db5gll	97	26	immune	immune	JJ
cord-264699-l8db5gll	97	27	system	system	NN
cord-264699-l8db5gll	97	28	and	and	CC
cord-264699-l8db5gll	97	29	altering	alter	VBG
cord-264699-l8db5gll	97	30	the	the	DT
cord-264699-l8db5gll	97	31	host	host	NN
cord-264699-l8db5gll	97	32	metabolic	metabolic	JJ
cord-264699-l8db5gll	97	33	balance	balance	NN
cord-264699-l8db5gll	97	34	,	,	,
cord-264699-l8db5gll	97	35	both	both	DT
cord-264699-l8db5gll	97	36	functions	function	NNS
cord-264699-l8db5gll	97	37	governed	govern	VBN
cord-264699-l8db5gll	97	38	by	by	IN
cord-264699-l8db5gll	97	39	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	97	40	[	[	-LRB-
cord-264699-l8db5gll	97	41	10	10	CD
cord-264699-l8db5gll	97	42	]	]	-RRB-
cord-264699-l8db5gll	97	43	.	.	.
cord-264699-l8db5gll	98	1	Vpr	Vpr	NNP
cord-264699-l8db5gll	98	2	reduces	reduce	VBZ
cord-264699-l8db5gll	98	3	tissue	tissue	NN
cord-264699-l8db5gll	98	4	sensitivity	sensitivity	NN
cord-264699-l8db5gll	98	5	to	to	IN
cord-264699-l8db5gll	98	6	insulin	insulin	NN
cord-264699-l8db5gll	98	7	by	by	IN
cord-264699-l8db5gll	98	8	potentiating	potentiate	VBG
cord-264699-l8db5gll	98	9	the	the	DT
cord-264699-l8db5gll	98	10	actions	action	NNS
cord-264699-l8db5gll	98	11	of	of	IN
cord-264699-l8db5gll	98	12	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	98	13	as	as	RB
cord-264699-l8db5gll	98	14	well	well	RB
cord-264699-l8db5gll	98	15	as	as	IN
cord-264699-l8db5gll	98	16	by	by	IN
cord-264699-l8db5gll	98	17	modulating	modulate	VBG
cord-264699-l8db5gll	98	18	the	the	DT
cord-264699-l8db5gll	98	19	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	98	20	activity	activity	NN
cord-264699-l8db5gll	98	21	of	of	IN
cord-264699-l8db5gll	98	22	insulin	insulin	NN
cord-264699-l8db5gll	98	23	(	(	-LRB-
cord-264699-l8db5gll	98	24	Figure	figure	NN
cord-264699-l8db5gll	98	25	3	3	CD
cord-264699-l8db5gll	98	26	)	)	-RRB-
cord-264699-l8db5gll	99	1	[	[	-LRB-
cord-264699-l8db5gll	99	2	37	37	CD
cord-264699-l8db5gll	99	3	,	,	,
cord-264699-l8db5gll	99	4	38	38	CD
cord-264699-l8db5gll	99	5	]	]	-RRB-
cord-264699-l8db5gll	99	6	.	.	.
cord-264699-l8db5gll	100	1	Insulin	insulin	NN
cord-264699-l8db5gll	100	2	uses	use	VBZ
cord-264699-l8db5gll	100	3	the	the	DT
cord-264699-l8db5gll	100	4	forkhead	forkhead	NNP
cord-264699-l8db5gll	100	5	transcription	transcription	NN
cord-264699-l8db5gll	100	6	factors	factor	NNS
cord-264699-l8db5gll	100	7	(	(	-LRB-
cord-264699-l8db5gll	100	8	FoxOs	foxos	NN
cord-264699-l8db5gll	100	9	)	)	-RRB-
cord-264699-l8db5gll	100	10	to	to	TO
cord-264699-l8db5gll	100	11	control	control	VB
cord-264699-l8db5gll	100	12	gene	gene	NN
cord-264699-l8db5gll	100	13	induction	induction	NN
cord-264699-l8db5gll	100	14	.	.	.
cord-264699-l8db5gll	101	1	Baseline	Baseline	NNP
cord-264699-l8db5gll	101	2	,	,	,
cord-264699-l8db5gll	101	3	unphosphorylated	unphosphorylated	JJ
cord-264699-l8db5gll	101	4	FoxOs	foxos	NN
cord-264699-l8db5gll	101	5	are	be	VBP
cord-264699-l8db5gll	101	6	active	active	JJ
cord-264699-l8db5gll	101	7	,	,	,
cord-264699-l8db5gll	101	8	reside	reside	VB
cord-264699-l8db5gll	101	9	in	in	IN
cord-264699-l8db5gll	101	10	the	the	DT
cord-264699-l8db5gll	101	11	nucleus	nucleus	NN
cord-264699-l8db5gll	101	12	and	and	CC
cord-264699-l8db5gll	101	13	bind	bind	VB
cord-264699-l8db5gll	101	14	to	to	IN
cord-264699-l8db5gll	101	15	their	-PRON-	PRP$
cord-264699-l8db5gll	101	16	responsive	responsive	JJ
cord-264699-l8db5gll	101	17	sequences	sequence	NNS
cord-264699-l8db5gll	101	18	in	in	IN
cord-264699-l8db5gll	101	19	the	the	DT
cord-264699-l8db5gll	101	20	promoter	promoter	NN
cord-264699-l8db5gll	101	21	region	region	NN
cord-264699-l8db5gll	101	22	of	of	IN
cord-264699-l8db5gll	101	23	insulin	insulin	NN
cord-264699-l8db5gll	101	24	-	-	HYPH
cord-264699-l8db5gll	101	25	responsive	responsive	JJ
cord-264699-l8db5gll	101	26	genes	gene	NNS
cord-264699-l8db5gll	101	27	.	.	.
cord-264699-l8db5gll	102	1	By	by	IN
cord-264699-l8db5gll	102	2	contrast	contrast	NN
cord-264699-l8db5gll	102	3	,	,	,
cord-264699-l8db5gll	102	4	insulin	insulin	NN
cord-264699-l8db5gll	102	5	activates	activate	VBZ
cord-264699-l8db5gll	102	6	Akt	Akt	NNP
cord-264699-l8db5gll	102	7	kinase	kinase	NN
cord-264699-l8db5gll	102	8	,	,	,
cord-264699-l8db5gll	102	9	which	which	WDT
cord-264699-l8db5gll	102	10	phosphorylates	phosphorylate	VBZ
cord-264699-l8db5gll	102	11	specific	specific	JJ
cord-264699-l8db5gll	102	12	serine	serine	NN
cord-264699-l8db5gll	102	13	and	and	CC
cord-264699-l8db5gll	102	14	threonine	threonine	NN
cord-264699-l8db5gll	102	15	residues	residue	NNS
cord-264699-l8db5gll	102	16	in	in	IN
cord-264699-l8db5gll	102	17	FoxOs	foxos	NN
cord-264699-l8db5gll	102	18	to	to	TO
cord-264699-l8db5gll	102	19	render	render	VB
cord-264699-l8db5gll	102	20	them	-PRON-	PRP
cord-264699-l8db5gll	102	21	inactive	inactive	JJ
cord-264699-l8db5gll	102	22	[	[	-LRB-
cord-264699-l8db5gll	102	23	39	39	CD
cord-264699-l8db5gll	102	24	]	]	-RRB-
cord-264699-l8db5gll	102	25	.	.	.
cord-264699-l8db5gll	103	1	Indeed	indeed	RB
cord-264699-l8db5gll	103	2	,	,	,
cord-264699-l8db5gll	103	3	once	once	RB
cord-264699-l8db5gll	103	4	FoxOs	foxos	NN
cord-264699-l8db5gll	103	5	are	be	VBP
cord-264699-l8db5gll	103	6	phosphorylated	phosphorylate	VBN
cord-264699-l8db5gll	103	7	at	at	IN
cord-264699-l8db5gll	103	8	specific	specific	JJ
cord-264699-l8db5gll	103	9	residues	residue	NNS
cord-264699-l8db5gll	103	10	,	,	,
cord-264699-l8db5gll	103	11	they	-PRON-	PRP
cord-264699-l8db5gll	103	12	lose	lose	VBP
cord-264699-l8db5gll	103	13	their	-PRON-	PRP$
cord-264699-l8db5gll	103	14	Figure	figure	NN
cord-264699-l8db5gll	103	15	2	2	CD
cord-264699-l8db5gll	103	16	.	.	.
cord-264699-l8db5gll	104	1	Linearized	linearized	JJ
cord-264699-l8db5gll	104	2	diagrams	diagram	NNS
cord-264699-l8db5gll	104	3	of	of	IN
cord-264699-l8db5gll	105	1	(	(	-LRB-
cord-264699-l8db5gll	105	2	i	i	NN
cord-264699-l8db5gll	105	3	)	)	-RRB-
cord-264699-l8db5gll	105	4	p300	p300	NNP
cord-264699-l8db5gll	105	5	,	,	,
cord-264699-l8db5gll	105	6	(	(	-LRB-
cord-264699-l8db5gll	105	7	ii	ii	NN
cord-264699-l8db5gll	105	8	)	)	-RRB-
cord-264699-l8db5gll	105	9	CtBP1	CtBP1	NNP
cord-264699-l8db5gll	105	10	,	,	,
cord-264699-l8db5gll	105	11	(	(	-LRB-
cord-264699-l8db5gll	105	12	iii	iii	NN
cord-264699-l8db5gll	105	13	)	)	-RRB-
cord-264699-l8db5gll	106	1	Vpr	Vpr	NNP
cord-264699-l8db5gll	106	2	,	,	,
cord-264699-l8db5gll	106	3	(	(	-LRB-
cord-264699-l8db5gll	106	4	iv	iv	LS
cord-264699-l8db5gll	106	5	)	)	-RRB-
cord-264699-l8db5gll	106	6	Tat	Tat	NNP
cord-264699-l8db5gll	106	7	,	,	,
cord-264699-l8db5gll	106	8	and	and	CC
cord-264699-l8db5gll	106	9	(	(	-LRB-
cord-264699-l8db5gll	106	10	v	v	LS
cord-264699-l8db5gll	106	11	)	)	-RRB-
cord-264699-l8db5gll	106	12	E1A	e1a	NN
cord-264699-l8db5gll	106	13	and	and	CC
cord-264699-l8db5gll	106	14	their	-PRON-	PRP$
cord-264699-l8db5gll	106	15	mutual	mutual	JJ
cord-264699-l8db5gll	106	16	-	-	HYPH
cord-264699-l8db5gll	106	17	interaction	interaction	NN
cord-264699-l8db5gll	106	18	domains	domain	NNS
cord-264699-l8db5gll	106	19	.	.	.
cord-264699-l8db5gll	107	1	Numerous	numerous	JJ
cord-264699-l8db5gll	107	2	transcription	transcription	NN
cord-264699-l8db5gll	107	3	factors	factor	NNS
cord-264699-l8db5gll	107	4	,	,	,
cord-264699-l8db5gll	107	5	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	107	6	regulators	regulator	NNS
cord-264699-l8db5gll	107	7	and	and	CC
cord-264699-l8db5gll	107	8	viral	viral	JJ
cord-264699-l8db5gll	107	9	molecules	molecule	NNS
cord-264699-l8db5gll	107	10	bind	bind	VBP
cord-264699-l8db5gll	107	11	the	the	DT
cord-264699-l8db5gll	107	12	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	107	13	coactivator	coactivator	NN
cord-264699-l8db5gll	107	14	p300	p300	NNP
cord-264699-l8db5gll	107	15	or	or	CC
cord-264699-l8db5gll	107	16	its	-PRON-	PRP$
cord-264699-l8db5gll	107	17	homolog	homolog	NN
cord-264699-l8db5gll	107	18	CBP	CBP	NNP
cord-264699-l8db5gll	107	19	.	.	.
cord-264699-l8db5gll	108	1	Binding	bind	VBG
cord-264699-l8db5gll	108	2	sites	site	NNS
cord-264699-l8db5gll	108	3	of	of	IN
cord-264699-l8db5gll	108	4	p160	p160	NN
cord-264699-l8db5gll	108	5	NR	NR	NNP
cord-264699-l8db5gll	108	6	coactivators	coactivator	NNS
cord-264699-l8db5gll	108	7	and	and	CC
cord-264699-l8db5gll	108	8	Vpr	Vpr	NNP
cord-264699-l8db5gll	108	9	overlap	overlap	VBP
cord-264699-l8db5gll	108	10	,	,	,
cord-264699-l8db5gll	108	11	and	and	CC
cord-264699-l8db5gll	108	12	both	both	DT
cord-264699-l8db5gll	108	13	bind	bind	VBP
cord-264699-l8db5gll	108	14	NRs	NRs	NNP
cord-264699-l8db5gll	108	15	and	and	CC
cord-264699-l8db5gll	108	16	p300	p300	NNP
cord-264699-l8db5gll	108	17	or	or	CC
cord-264699-l8db5gll	108	18	CBP	CBP	NNP
cord-264699-l8db5gll	108	19	.	.	.
cord-264699-l8db5gll	109	1	Thus	thus	RB
cord-264699-l8db5gll	109	2	,	,	,
cord-264699-l8db5gll	109	3	Vpr	Vpr	NNP
cord-264699-l8db5gll	109	4	mimics	mimic	VBZ
cord-264699-l8db5gll	109	5	the	the	DT
cord-264699-l8db5gll	109	6	host	host	NN
cord-264699-l8db5gll	109	7	p160	p160	NN
cord-264699-l8db5gll	109	8	NR	NR	NNP
cord-264699-l8db5gll	109	9	coactivators	coactivator	NNS
cord-264699-l8db5gll	109	10	and	and	CC
cord-264699-l8db5gll	109	11	enhances	enhance	VBZ
cord-264699-l8db5gll	109	12	NR	NR	NNP
cord-264699-l8db5gll	109	13	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	109	14	activity	activity	NN
cord-264699-l8db5gll	109	15	.	.	.
cord-264699-l8db5gll	110	1	p300	p300	NNP
cord-264699-l8db5gll	110	2	/	/	SYM
cord-264699-l8db5gll	110	3	CBP	CBP	NNP
cord-264699-l8db5gll	110	4	facilitates	facilitate	VBZ
cord-264699-l8db5gll	110	5	attraction	attraction	NN
cord-264699-l8db5gll	110	6	of	of	IN
cord-264699-l8db5gll	110	7	transcription	transcription	NN
cord-264699-l8db5gll	110	8	factors	factor	NNS
cord-264699-l8db5gll	110	9	,	,	,
cord-264699-l8db5gll	110	10	cofactors	cofactor	NNS
cord-264699-l8db5gll	110	11	and	and	CC
cord-264699-l8db5gll	110	12	general	general	JJ
cord-264699-l8db5gll	110	13	transcription	transcription	NN
cord-264699-l8db5gll	110	14	complexes	complex	NNS
cord-264699-l8db5gll	110	15	by	by	IN
cord-264699-l8db5gll	110	16	loosening	loosen	VBG
cord-264699-l8db5gll	110	17	the	the	DT
cord-264699-l8db5gll	110	18	histone	histone	JJ
cord-264699-l8db5gll	110	19	-	-	HYPH
cord-264699-l8db5gll	110	20	DNA	dna	NN
cord-264699-l8db5gll	110	21	interaction	interaction	NN
cord-264699-l8db5gll	110	22	through	through	IN
cord-264699-l8db5gll	110	23	acetylation	acetylation	NN
cord-264699-l8db5gll	110	24	of	of	IN
cord-264699-l8db5gll	110	25	histone	histone	NN
cord-264699-l8db5gll	110	26	tails	tail	NNS
cord-264699-l8db5gll	110	27	by	by	IN
cord-264699-l8db5gll	110	28	its	-PRON-	PRP$
cord-264699-l8db5gll	110	29	HAT	hat	NN
cord-264699-l8db5gll	110	30	domain	domain	NN
cord-264699-l8db5gll	110	31	.	.	.
cord-264699-l8db5gll	111	1	The	the	DT
cord-264699-l8db5gll	111	2	N	n	CD
cord-264699-l8db5gll	111	3	-	-	HYPH
cord-264699-l8db5gll	111	4	terminal	terminal	JJ
cord-264699-l8db5gll	111	5	portion	portion	NN
cord-264699-l8db5gll	111	6	of	of	IN
cord-264699-l8db5gll	111	7	CtBP1	CtBP1	NNP
cord-264699-l8db5gll	111	8	interacts	interact	VBZ
cord-264699-l8db5gll	111	9	physically	physically	RB
cord-264699-l8db5gll	111	10	with	with	IN
cord-264699-l8db5gll	111	11	HDAC5	HDAC5	NNS
cord-264699-l8db5gll	111	12	and	and	CC
cord-264699-l8db5gll	111	13	Rb	Rb	NNP
cord-264699-l8db5gll	111	14	,	,	,
cord-264699-l8db5gll	111	15	which	which	WDT
cord-264699-l8db5gll	111	16	repress	repress	VBP
cord-264699-l8db5gll	111	17	transcription	transcription	NN
cord-264699-l8db5gll	111	18	.	.	.
cord-264699-l8db5gll	112	1	CtBP1	CtBP1	NNP
cord-264699-l8db5gll	112	2	regulates	regulate	VBZ
cord-264699-l8db5gll	112	3	interaction	interaction	NN
cord-264699-l8db5gll	112	4	with	with	IN
cord-264699-l8db5gll	112	5	its	-PRON-	PRP$
cord-264699-l8db5gll	112	6	binding	bind	VBG
cord-264699-l8db5gll	112	7	partners	partner	NNS
cord-264699-l8db5gll	112	8	by	by	IN
cord-264699-l8db5gll	112	9	sensing	sense	VBG
cord-264699-l8db5gll	112	10	NADH	NADH	NNP
cord-264699-l8db5gll	112	11	levels	level	NNS
cord-264699-l8db5gll	112	12	through	through	IN
cord-264699-l8db5gll	112	13	its	-PRON-	PRP$
cord-264699-l8db5gll	112	14	NAD	NAD	NNP
cord-264699-l8db5gll	112	15	+	+	CC
cord-264699-l8db5gll	112	16	-binding	-binding	NN
cord-264699-l8db5gll	112	17	domain	domain	NN
cord-264699-l8db5gll	112	18	.	.	.
cord-264699-l8db5gll	113	1	E1A	E1A	NNP
cord-264699-l8db5gll	113	2	binds	bind	VBZ
cord-264699-l8db5gll	113	3	to	to	IN
cord-264699-l8db5gll	113	4	the	the	DT
cord-264699-l8db5gll	113	5	C	C	NNP
cord-264699-l8db5gll	113	6	-	-	HYPH
cord-264699-l8db5gll	113	7	terminal	terminal	NN
cord-264699-l8db5gll	113	8	portion	portion	NN
cord-264699-l8db5gll	113	9	of	of	IN
cord-264699-l8db5gll	113	10	p300	p300	NNP
cord-264699-l8db5gll	113	11	and	and	CC
cord-264699-l8db5gll	113	12	associates	associate	NNS
cord-264699-l8db5gll	113	13	physically	physically	RB
cord-264699-l8db5gll	113	14	with	with	IN
cord-264699-l8db5gll	113	15	the	the	DT
cord-264699-l8db5gll	113	16	N	n	CD
cord-264699-l8db5gll	113	17	-	-	HYPH
cord-264699-l8db5gll	113	18	terminal	terminal	JJ
cord-264699-l8db5gll	113	19	portion	portion	NN
cord-264699-l8db5gll	113	20	of	of	IN
cord-264699-l8db5gll	113	21	CtBP1	CtBP1	NNP
cord-264699-l8db5gll	113	22	through	through	IN
cord-264699-l8db5gll	113	23	its	-PRON-	PRP$
cord-264699-l8db5gll	113	24	C	c	NN
cord-264699-l8db5gll	113	25	-	-	HYPH
cord-264699-l8db5gll	113	26	terminal	terminal	NN
cord-264699-l8db5gll	113	27	end	end	NN
cord-264699-l8db5gll	113	28	.	.	.
cord-264699-l8db5gll	114	1	The	the	DT
cord-264699-l8db5gll	114	2	HAT	hat	NN
cord-264699-l8db5gll	114	3	domain	domain	NN
cord-264699-l8db5gll	114	4	of	of	IN
cord-264699-l8db5gll	114	5	p300	p300	NN
cord-264699-l8db5gll	114	6	and	and	CC
cord-264699-l8db5gll	114	7	the	the	DT
cord-264699-l8db5gll	114	8	NAD	NAD	NNP
cord-264699-l8db5gll	114	9	+	+	CC
cord-264699-l8db5gll	114	10	-binding	-binding	NN
cord-264699-l8db5gll	114	11	domain	domain	NN
cord-264699-l8db5gll	114	12	of	of	IN
cord-264699-l8db5gll	114	13	CtBP1	CtBP1	NNP
cord-264699-l8db5gll	114	14	are	be	VBP
cord-264699-l8db5gll	114	15	indicated	indicate	VBN
cord-264699-l8db5gll	114	16	in	in	IN
cord-264699-l8db5gll	114	17	red	red	NN
cord-264699-l8db5gll	114	18	.	.	.
cord-264699-l8db5gll	115	1	This	this	DT
cord-264699-l8db5gll	115	2	figure	figure	NN
cord-264699-l8db5gll	115	3	is	be	VBZ
cord-264699-l8db5gll	115	4	based	base	VBN
cord-264699-l8db5gll	115	5	on	on	IN
cord-264699-l8db5gll	115	6	Refs	ref	NNS
cord-264699-l8db5gll	115	7	[	[	-LRB-
cord-264699-l8db5gll	115	8	16	16	CD
cord-264699-l8db5gll	115	9	,	,	,
cord-264699-l8db5gll	115	10	33	33	CD
cord-264699-l8db5gll	115	11	,	,	,
cord-264699-l8db5gll	115	12	45	45	CD
cord-264699-l8db5gll	115	13	]	]	-RRB-
cord-264699-l8db5gll	115	14	.	.	.
cord-264699-l8db5gll	116	1	Abbreviations	abbreviation	NNS
cord-264699-l8db5gll	116	2	:	:	:
cord-264699-l8db5gll	117	1	CREB	CREB	NNP
cord-264699-l8db5gll	117	2	,	,	,
cord-264699-l8db5gll	117	3	CRE	CRE	NNP
cord-264699-l8db5gll	117	4	-	-	HYPH
cord-264699-l8db5gll	117	5	binding	bind	VBG
cord-264699-l8db5gll	117	6	protein	protein	NN
cord-264699-l8db5gll	117	7	;	;	:
cord-264699-l8db5gll	117	8	HAT	hat	NN
cord-264699-l8db5gll	117	9	,	,	,
cord-264699-l8db5gll	117	10	histone	histone	NN
cord-264699-l8db5gll	117	11	acetyltransferase	acetyltransferase	NN
cord-264699-l8db5gll	117	12	;	;	:
cord-264699-l8db5gll	117	13	HDAC5	HDAC5	NNP
cord-264699-l8db5gll	117	14	,	,	,
cord-264699-l8db5gll	117	15	histone	histone	NNP
cord-264699-l8db5gll	117	16	deacetylases	deacetylases	NNP
cord-264699-l8db5gll	117	17	5	5	CD
cord-264699-l8db5gll	117	18	;	;	:
cord-264699-l8db5gll	117	19	NF	NF	NNP
cord-264699-l8db5gll	117	20	-	-	HYPH
cord-264699-l8db5gll	117	21	kB	kB	NNP
cord-264699-l8db5gll	117	22	,	,	,
cord-264699-l8db5gll	117	23	nuclear	nuclear	JJ
cord-264699-l8db5gll	117	24	factor	factor	NN
cord-264699-l8db5gll	117	25	-	-	HYPH
cord-264699-l8db5gll	117	26	kB	kB	NNP
cord-264699-l8db5gll	117	27	;	;	:
cord-264699-l8db5gll	117	28	NAD	NAD	NNP
cord-264699-l8db5gll	117	29	,	,	,
cord-264699-l8db5gll	117	30	nicotinamide	nicotinamide	NN
cord-264699-l8db5gll	117	31	adenine	adenine	NN
cord-264699-l8db5gll	117	32	dinucleotide	dinucleotide	NN
cord-264699-l8db5gll	117	33	;	;	:
cord-264699-l8db5gll	117	34	NR	NR	NNP
cord-264699-l8db5gll	117	35	,	,	,
cord-264699-l8db5gll	117	36	nuclear	nuclear	JJ
cord-264699-l8db5gll	117	37	hormone	hormone	NN
cord-264699-l8db5gll	117	38	receptor	receptor	NN
cord-264699-l8db5gll	117	39	;	;	:
cord-264699-l8db5gll	117	40	p	p	NN
cord-264699-l8db5gll	117	41	/	/	SYM
cord-264699-l8db5gll	117	42	CAF	CAF	NNP
cord-264699-l8db5gll	117	43	,	,	,
cord-264699-l8db5gll	117	44	p300	p300	NNP
cord-264699-l8db5gll	117	45	/	/	SYM
cord-264699-l8db5gll	117	46	CBP	CBP	NNP
cord-264699-l8db5gll	117	47	-	-	HYPH
cord-264699-l8db5gll	117	48	associating	associate	VBG
cord-264699-l8db5gll	117	49	factor	factor	NN
cord-264699-l8db5gll	117	50	;	;	:
cord-264699-l8db5gll	117	51	pTEFb	pTEFb	NNS
cord-264699-l8db5gll	117	52	,	,	,
cord-264699-l8db5gll	117	53	positive	positive	JJ
cord-264699-l8db5gll	117	54	-	-	HYPH
cord-264699-l8db5gll	117	55	acting	act	VBG
cord-264699-l8db5gll	117	56	transcription	transcription	NN
cord-264699-l8db5gll	117	57	elongation	elongation	NN
cord-264699-l8db5gll	117	58	factor	factor	NN
cord-264699-l8db5gll	117	59	b	b	NN
cord-264699-l8db5gll	117	60	;	;	:
cord-264699-l8db5gll	117	61	Rb	Rb	NNP
cord-264699-l8db5gll	117	62	,	,	,
cord-264699-l8db5gll	117	63	retinoblastoma	retinoblastoma	NN
cord-264699-l8db5gll	117	64	protein	protein	NN
cord-264699-l8db5gll	117	65	;	;	:
cord-264699-l8db5gll	117	66	SF-1	SF-1	NNP
cord-264699-l8db5gll	117	67	,	,	,
cord-264699-l8db5gll	117	68	steroidogenic	steroidogenic	NNP
cord-264699-l8db5gll	117	69	factor-1	factor-1	NNP
cord-264699-l8db5gll	117	70	;	;	:
cord-264699-l8db5gll	117	71	STAT2	STAT2	NNS
cord-264699-l8db5gll	117	72	,	,	,
cord-264699-l8db5gll	117	73	signal	signal	NN
cord-264699-l8db5gll	117	74	transducer	transducer	NN
cord-264699-l8db5gll	117	75	and	and	CC
cord-264699-l8db5gll	117	76	activator	activator	NN
cord-264699-l8db5gll	117	77	of	of	IN
cord-264699-l8db5gll	117	78	transcription	transcription	NN
cord-264699-l8db5gll	117	79	2	2	CD
cord-264699-l8db5gll	117	80	;	;	:
cord-264699-l8db5gll	117	81	TFIIB	TFIIB	NNP
cord-264699-l8db5gll	117	82	,	,	,
cord-264699-l8db5gll	117	83	transcription	transcription	NN
cord-264699-l8db5gll	117	84	factor	factor	NN
cord-264699-l8db5gll	117	85	IIB	IIB	NNP
cord-264699-l8db5gll	117	86	.	.	.
cord-264699-l8db5gll	118	1	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	118	2	activity	activity	NN
cord-264699-l8db5gll	118	3	,	,	,
cord-264699-l8db5gll	118	4	by	by	IN
cord-264699-l8db5gll	118	5	binding	bind	VBG
cord-264699-l8db5gll	118	6	to	to	IN
cord-264699-l8db5gll	118	7	and	and	CC
cord-264699-l8db5gll	118	8	translocating	translocate	VBG
cord-264699-l8db5gll	118	9	into	into	IN
cord-264699-l8db5gll	118	10	the	the	DT
cord-264699-l8db5gll	118	11	cytoplasm	cytoplasm	NN
cord-264699-l8db5gll	118	12	with	with	IN
cord-264699-l8db5gll	118	13	proteins	protein	NNS
cord-264699-l8db5gll	118	14	of	of	IN
cord-264699-l8db5gll	118	15	the	the	DT
cord-264699-l8db5gll	118	16	14	14	CD
cord-264699-l8db5gll	118	17	-	-	SYM
cord-264699-l8db5gll	118	18	3	3	CD
cord-264699-l8db5gll	118	19	-	-	SYM
cord-264699-l8db5gll	118	20	3	3	CD
cord-264699-l8db5gll	118	21	family	family	NN
cord-264699-l8db5gll	118	22	[	[	-LRB-
cord-264699-l8db5gll	118	23	39	39	CD
cord-264699-l8db5gll	118	24	]	]	-RRB-
cord-264699-l8db5gll	118	25	.	.	.
cord-264699-l8db5gll	119	1	We	-PRON-	PRP
cord-264699-l8db5gll	119	2	have	have	VBP
cord-264699-l8db5gll	119	3	found	find	VBN
cord-264699-l8db5gll	119	4	that	that	IN
cord-264699-l8db5gll	119	5	Vpr	Vpr	NNP
cord-264699-l8db5gll	119	6	moderately	moderately	RB
cord-264699-l8db5gll	119	7	inhibits	inhibit	VBZ
cord-264699-l8db5gll	119	8	insulininduced	insulininduce	VBN
cord-264699-l8db5gll	119	9	translocation	translocation	NN
cord-264699-l8db5gll	119	10	of	of	IN
cord-264699-l8db5gll	119	11	FoxO3a	FoxO3a	NNP
cord-264699-l8db5gll	119	12	into	into	IN
cord-264699-l8db5gll	119	13	the	the	DT
cord-264699-l8db5gll	119	14	cytoplasm	cytoplasm	NN
cord-264699-l8db5gll	119	15	through	through	IN
cord-264699-l8db5gll	119	16	inhibiting	inhibit	VBG
cord-264699-l8db5gll	119	17	its	-PRON-	PRP$
cord-264699-l8db5gll	119	18	association	association	NN
cord-264699-l8db5gll	119	19	with	with	IN
cord-264699-l8db5gll	119	20	14	14	CD
cord-264699-l8db5gll	119	21	-	-	SYM
cord-264699-l8db5gll	119	22	3	3	CD
cord-264699-l8db5gll	119	23	-	-	SYM
cord-264699-l8db5gll	119	24	3	3	CD
cord-264699-l8db5gll	119	25	[	[	-LRB-
cord-264699-l8db5gll	119	26	37	37	CD
cord-264699-l8db5gll	119	27	]	]	-RRB-
cord-264699-l8db5gll	119	28	.	.	.
cord-264699-l8db5gll	120	1	Based	base	VBN
cord-264699-l8db5gll	120	2	on	on	IN
cord-264699-l8db5gll	120	3	these	these	DT
cord-264699-l8db5gll	120	4	in	in	FW
cord-264699-l8db5gll	120	5	vitro	vitro	FW
cord-264699-l8db5gll	120	6	findings	finding	NNS
cord-264699-l8db5gll	120	7	,	,	,
cord-264699-l8db5gll	120	8	Vpr	Vpr	NNP
cord-264699-l8db5gll	120	9	might	may	MD
cord-264699-l8db5gll	120	10	be	be	VB
cord-264699-l8db5gll	120	11	a	a	DT
cord-264699-l8db5gll	120	12	key	key	JJ
cord-264699-l8db5gll	120	13	viral	viral	JJ
cord-264699-l8db5gll	120	14	factor	factor	NN
cord-264699-l8db5gll	120	15	that	that	WDT
cord-264699-l8db5gll	120	16	induces	induce	VBZ
cord-264699-l8db5gll	120	17	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	120	18	,	,	,
cord-264699-l8db5gll	120	19	insulin	insulin	NN
cord-264699-l8db5gll	120	20	resistance	resistance	NN
cord-264699-l8db5gll	120	21	and	and	CC
cord-264699-l8db5gll	120	22	hyperlipidemia	hyperlipidemia	NN
cord-264699-l8db5gll	120	23	by	by	IN
cord-264699-l8db5gll	120	24	interfering	interfere	VBG
cord-264699-l8db5gll	120	25	with	with	IN
cord-264699-l8db5gll	120	26	and/or	and/or	CC
cord-264699-l8db5gll	120	27	modulating	modulate	VBG
cord-264699-l8db5gll	120	28	cellular	cellular	JJ
cord-264699-l8db5gll	120	29	activities	activity	NNS
cord-264699-l8db5gll	120	30	,	,	,
cord-264699-l8db5gll	120	31	such	such	JJ
cord-264699-l8db5gll	120	32	as	as	IN
cord-264699-l8db5gll	120	33	transactivation	transactivation	NN
cord-264699-l8db5gll	120	34	of	of	IN
cord-264699-l8db5gll	120	35	NRs	NRs	NNP
cord-264699-l8db5gll	120	36	and	and	CC
cord-264699-l8db5gll	120	37	insulin	insulin	NN
cord-264699-l8db5gll	120	38	[	[	-LRB-
cord-264699-l8db5gll	120	39	26	26	CD
cord-264699-l8db5gll	120	40	]	]	-RRB-
cord-264699-l8db5gll	120	41	.	.	.
cord-264699-l8db5gll	121	1	Unpublished	unpublished	JJ
cord-264699-l8db5gll	121	2	information	information	NN
cord-264699-l8db5gll	121	3	indicates	indicate	VBZ
cord-264699-l8db5gll	121	4	that	that	IN
cord-264699-l8db5gll	121	5	induction	induction	NN
cord-264699-l8db5gll	121	6	of	of	IN
cord-264699-l8db5gll	121	7	insulin	insulin	NN
cord-264699-l8db5gll	121	8	resistance	resistance	NN
cord-264699-l8db5gll	121	9	by	by	IN
cord-264699-l8db5gll	121	10	Vpr	Vpr	NNP
cord-264699-l8db5gll	121	11	might	may	MD
cord-264699-l8db5gll	121	12	be	be	VB
cord-264699-l8db5gll	121	13	compounded	compound	VBN
cord-264699-l8db5gll	121	14	by	by	IN
cord-264699-l8db5gll	121	15	the	the	DT
cord-264699-l8db5gll	121	16	ability	ability	NN
cord-264699-l8db5gll	121	17	of	of	IN
cord-264699-l8db5gll	121	18	the	the	DT
cord-264699-l8db5gll	121	19	viral	viral	JJ
cord-264699-l8db5gll	121	20	protein	protein	NN
cord-264699-l8db5gll	121	21	to	to	TO
cord-264699-l8db5gll	121	22	interfere	interfere	VB
cord-264699-l8db5gll	121	23	with	with	IN
cord-264699-l8db5gll	121	24	signal	signal	NN
cord-264699-l8db5gll	121	25	transduction	transduction	NN
cord-264699-l8db5gll	121	26	by	by	IN
cord-264699-l8db5gll	121	27	another	another	DT
cord-264699-l8db5gll	121	28	NR	NR	NNP
cord-264699-l8db5gll	121	29	,	,	,
cord-264699-l8db5gll	121	30	peroxisome	peroxisome	NN
cord-264699-l8db5gll	121	31	proliferation	proliferation	NN
cord-264699-l8db5gll	121	32	receptor	receptor	NN
cord-264699-l8db5gll	122	1	g.	g.	NNP
cord-264699-l8db5gll	123	1	*	*	NFP
cord-264699-l8db5gll	123	2	Paget	Paget	NNP
cord-264699-l8db5gll	123	3	's	's	POS
cord-264699-l8db5gll	123	4	disease	disease	NN
cord-264699-l8db5gll	123	5	of	of	IN
cord-264699-l8db5gll	123	6	bone	bone	NN
cord-264699-l8db5gll	123	7	and	and	CC
cord-264699-l8db5gll	123	8	the	the	DT
cord-264699-l8db5gll	123	9	measles	measle	NNS
cord-264699-l8db5gll	123	10	virus	virus	NN
cord-264699-l8db5gll	123	11	Paget	Paget	NNP
cord-264699-l8db5gll	123	12	's	's	POS
cord-264699-l8db5gll	123	13	disease	disease	NN
cord-264699-l8db5gll	123	14	of	of	IN
cord-264699-l8db5gll	123	15	bone	bone	NN
cord-264699-l8db5gll	123	16	is	be	VBZ
cord-264699-l8db5gll	123	17	a	a	DT
cord-264699-l8db5gll	123	18	chronic	chronic	JJ
cord-264699-l8db5gll	123	19	,	,	,
cord-264699-l8db5gll	123	20	focal	focal	JJ
cord-264699-l8db5gll	123	21	,	,	,
cord-264699-l8db5gll	123	22	skeletal	skeletal	JJ
cord-264699-l8db5gll	123	23	disorder	disorder	NN
cord-264699-l8db5gll	123	24	that	that	WDT
cord-264699-l8db5gll	123	25	causes	cause	VBZ
cord-264699-l8db5gll	123	26	bone	bone	NN
cord-264699-l8db5gll	123	27	deformities	deformity	NNS
cord-264699-l8db5gll	123	28	and	and	CC
cord-264699-l8db5gll	123	29	fractures	fracture	NNS
cord-264699-l8db5gll	123	30	as	as	IN
cord-264699-l8db5gll	123	31	a	a	DT
cord-264699-l8db5gll	123	32	result	result	NN
cord-264699-l8db5gll	123	33	of	of	IN
cord-264699-l8db5gll	123	34	uncoupled	uncoupled	JJ
cord-264699-l8db5gll	123	35	bone	bone	NN
cord-264699-l8db5gll	123	36	remodeling	remodeling	NN
cord-264699-l8db5gll	123	37	[	[	-LRB-
cord-264699-l8db5gll	123	38	40	40	CD
cord-264699-l8db5gll	123	39	]	]	-RRB-
cord-264699-l8db5gll	123	40	.	.	.
cord-264699-l8db5gll	124	1	The	the	DT
cord-264699-l8db5gll	124	2	primary	primary	JJ
cord-264699-l8db5gll	124	3	abnormality	abnormality	NN
cord-264699-l8db5gll	124	4	of	of	IN
cord-264699-l8db5gll	124	5	this	this	DT
cord-264699-l8db5gll	124	6	disease	disease	NN
cord-264699-l8db5gll	124	7	resides	reside	VBZ
cord-264699-l8db5gll	124	8	in	in	IN
cord-264699-l8db5gll	124	9	the	the	DT
cord-264699-l8db5gll	124	10	osteoclasts	osteoclast	NNS
cord-264699-l8db5gll	124	11	,	,	,
cord-264699-l8db5gll	124	12	which	which	WDT
cord-264699-l8db5gll	124	13	demonstrate	demonstrate	VBP
cord-264699-l8db5gll	124	14	increased	increase	VBN
cord-264699-l8db5gll	124	15	capacity	capacity	NN
cord-264699-l8db5gll	124	16	for	for	IN
cord-264699-l8db5gll	124	17	bone	bone	NN
cord-264699-l8db5gll	124	18	resorption	resorption	NN
cord-264699-l8db5gll	124	19	and	and	CC
cord-264699-l8db5gll	124	20	hypersensitivity	hypersensitivity	NN
cord-264699-l8db5gll	124	21	to	to	IN
cord-264699-l8db5gll	124	22	vitamin	vitamin	NN
cord-264699-l8db5gll	124	23	D	d	NN
cord-264699-l8db5gll	124	24	[	[	-LRB-
cord-264699-l8db5gll	124	25	40	40	CD
cord-264699-l8db5gll	124	26	]	]	-RRB-
cord-264699-l8db5gll	124	27	.	.	.
cord-264699-l8db5gll	125	1	Immunocytochemical	Immunocytochemical	NNP
cord-264699-l8db5gll	125	2	studies	study	NNS
cord-264699-l8db5gll	125	3	have	have	VBP
cord-264699-l8db5gll	125	4	shown	show	VBN
cord-264699-l8db5gll	125	5	that	that	IN
cord-264699-l8db5gll	125	6	osteoclasts	osteoclast	NNS
cord-264699-l8db5gll	125	7	from	from	IN
cord-264699-l8db5gll	125	8	patients	patient	NNS
cord-264699-l8db5gll	125	9	with	with	IN
cord-264699-l8db5gll	125	10	Paget	Paget	NNP
cord-264699-l8db5gll	125	11	's	's	POS
cord-264699-l8db5gll	125	12	disease	disease	NN
cord-264699-l8db5gll	125	13	of	of	IN
cord-264699-l8db5gll	125	14	bone	bone	NN
cord-264699-l8db5gll	125	15	contain	contain	VBP
cord-264699-l8db5gll	125	16	paramyxoviral	paramyxoviral	JJ
cord-264699-l8db5gll	125	17	-	-	HYPH
cord-264699-l8db5gll	125	18	like	like	JJ
cord-264699-l8db5gll	125	19	nuclear	nuclear	JJ
cord-264699-l8db5gll	125	20	inclusions	inclusion	NNS
cord-264699-l8db5gll	125	21	that	that	WDT
cord-264699-l8db5gll	125	22	cross	cross	NN
cord-264699-l8db5gll	125	23	-	-	NN
cord-264699-l8db5gll	125	24	react	react	VB
cord-264699-l8db5gll	125	25	with	with	IN
cord-264699-l8db5gll	125	26	antibodies	antibody	NNS
cord-264699-l8db5gll	125	27	to	to	IN
cord-264699-l8db5gll	125	28	measles	measle	NNS
cord-264699-l8db5gll	125	29	virus	virus	NN
cord-264699-l8db5gll	125	30	,	,	,
cord-264699-l8db5gll	125	31	respiratory	respiratory	JJ
cord-264699-l8db5gll	125	32	syncytial	syncytial	JJ
cord-264699-l8db5gll	125	33	virus	virus	NN
cord-264699-l8db5gll	125	34	and	and	CC
cord-264699-l8db5gll	125	35	canine	canine	JJ
cord-264699-l8db5gll	125	36	distemper	distemper	NN
cord-264699-l8db5gll	125	37	virus	virus	NN
cord-264699-l8db5gll	125	38	nucleocapsid	nucleocapsid	NN
cord-264699-l8db5gll	125	39	antigen	antigen	NNP
cord-264699-l8db5gll	125	40	[	[	-LRB-
cord-264699-l8db5gll	125	41	40	40	CD
cord-264699-l8db5gll	125	42	]	]	-RRB-
cord-264699-l8db5gll	125	43	.	.	.
cord-264699-l8db5gll	126	1	Nucleocapsid	nucleocapsid	JJ
cord-264699-l8db5gll	126	2	transcripts	transcript	NNS
cord-264699-l8db5gll	126	3	of	of	IN
cord-264699-l8db5gll	126	4	measles	measle	NNS
cord-264699-l8db5gll	126	5	virus	virus	NN
cord-264699-l8db5gll	126	6	(	(	-LRB-
cord-264699-l8db5gll	126	7	MVNP	MVNP	NNP
cord-264699-l8db5gll	126	8	)	)	-RRB-
cord-264699-l8db5gll	126	9	,	,	,
cord-264699-l8db5gll	126	10	the	the	DT
cord-264699-l8db5gll	126	11	negative	negative	JJ
cord-264699-l8db5gll	126	12	single	single	JJ
cord-264699-l8db5gll	126	13	-	-	HYPH
cord-264699-l8db5gll	126	14	strand	strand	NN
cord-264699-l8db5gll	126	15	RNA	RNA	NNP
cord-264699-l8db5gll	126	16	virus	virus	NN
cord-264699-l8db5gll	126	17	of	of	IN
cord-264699-l8db5gll	126	18	the	the	DT
cord-264699-l8db5gll	126	19	Paramyxoviridae	Paramyxoviridae	NNP
cord-264699-l8db5gll	126	20	family	family	NN
cord-264699-l8db5gll	126	21	,	,	,
cord-264699-l8db5gll	126	22	have	have	VBP
cord-264699-l8db5gll	126	23	also	also	RB
cord-264699-l8db5gll	126	24	been	be	VBN
cord-264699-l8db5gll	126	25	detected	detect	VBN
cord-264699-l8db5gll	126	26	in	in	IN
cord-264699-l8db5gll	126	27	osteoclasts	osteoclast	NNS
cord-264699-l8db5gll	126	28	from	from	IN
cord-264699-l8db5gll	126	29	patients	patient	NNS
cord-264699-l8db5gll	126	30	with	with	IN
cord-264699-l8db5gll	126	31	Paget	Paget	NNP
cord-264699-l8db5gll	126	32	's	's	POS
cord-264699-l8db5gll	126	33	disease	disease	NN
cord-264699-l8db5gll	126	34	of	of	IN
cord-264699-l8db5gll	126	35	bone	bone	NN
cord-264699-l8db5gll	126	36	[	[	-LRB-
cord-264699-l8db5gll	126	37	41	41	CD
cord-264699-l8db5gll	126	38	]	]	-RRB-
cord-264699-l8db5gll	126	39	.	.	.
cord-264699-l8db5gll	127	1	Indeed	indeed	RB
cord-264699-l8db5gll	127	2	,	,	,
cord-264699-l8db5gll	127	3	forced	force	VBN
cord-264699-l8db5gll	127	4	expression	expression	NN
cord-264699-l8db5gll	127	5	of	of	IN
cord-264699-l8db5gll	127	6	MVNP	MVNP	NNP
cord-264699-l8db5gll	127	7	in	in	IN
cord-264699-l8db5gll	127	8	normal	normal	JJ
cord-264699-l8db5gll	127	9	osteoclast	osteoclast	NN
cord-264699-l8db5gll	127	10	precursor	precursor	NN
cord-264699-l8db5gll	127	11	cells	cell	NNS
cord-264699-l8db5gll	127	12	enhances	enhance	VBZ
cord-264699-l8db5gll	127	13	formation	formation	NN
cord-264699-l8db5gll	127	14	of	of	IN
cord-264699-l8db5gll	127	15	mature	mature	JJ
cord-264699-l8db5gll	127	16	osteoclasts	osteoclast	NNS
cord-264699-l8db5gll	127	17	that	that	WDT
cord-264699-l8db5gll	127	18	possess	possess	VBP
cord-264699-l8db5gll	127	19	many	many	JJ
cord-264699-l8db5gll	127	20	characteristics	characteristic	NNS
cord-264699-l8db5gll	127	21	of	of	IN
cord-264699-l8db5gll	127	22	those	those	DT
cord-264699-l8db5gll	127	23	in	in	IN
cord-264699-l8db5gll	127	24	patients	patient	NNS
cord-264699-l8db5gll	127	25	with	with	IN
cord-264699-l8db5gll	127	26	Paget	Paget	NNP
cord-264699-l8db5gll	127	27	's	's	POS
cord-264699-l8db5gll	127	28	disease	disease	NN
cord-264699-l8db5gll	127	29	,	,	,
cord-264699-l8db5gll	127	30	including	include	VBG
cord-264699-l8db5gll	127	31	increased	increase	VBN
cord-264699-l8db5gll	127	32	sensitivity	sensitivity	NN
cord-264699-l8db5gll	127	33	to	to	IN
cord-264699-l8db5gll	127	34	vitamin	vitamin	NN
cord-264699-l8db5gll	127	35	D	d	NN
cord-264699-l8db5gll	127	36	[	[	-LRB-
cord-264699-l8db5gll	127	37	40	40	CD
cord-264699-l8db5gll	127	38	]	]	-RRB-
cord-264699-l8db5gll	127	39	.	.	.
cord-264699-l8db5gll	128	1	Transgenic	transgenic	JJ
cord-264699-l8db5gll	128	2	expression	expression	NN
cord-264699-l8db5gll	128	3	of	of	IN
cord-264699-l8db5gll	128	4	MVNP	MVNP	NNP
cord-264699-l8db5gll	128	5	induces	induce	VBZ
cord-264699-l8db5gll	128	6	bone	bone	NN
cord-264699-l8db5gll	128	7	lesions	lesion	NNS
cord-264699-l8db5gll	128	8	similar	similar	JJ
cord-264699-l8db5gll	128	9	to	to	IN
cord-264699-l8db5gll	128	10	those	those	DT
cord-264699-l8db5gll	128	11	found	find	VBN
cord-264699-l8db5gll	128	12	in	in	IN
cord-264699-l8db5gll	128	13	Paget	Paget	NNP
cord-264699-l8db5gll	128	14	's	's	POS
cord-264699-l8db5gll	128	15	disease	disease	NN
cord-264699-l8db5gll	128	16	[	[	-LRB-
cord-264699-l8db5gll	128	17	42	42	CD
cord-264699-l8db5gll	128	18	]	]	-RRB-
cord-264699-l8db5gll	128	19	.	.	.
cord-264699-l8db5gll	129	1	Osteoclasts	Osteoclasts	NNP
cord-264699-l8db5gll	129	2	that	that	WDT
cord-264699-l8db5gll	129	3	express	express	VBP
cord-264699-l8db5gll	129	4	MVNP	MVNP	NNP
cord-264699-l8db5gll	129	5	demonstrate	demonstrate	VBP
cord-264699-l8db5gll	129	6	increased	increase	VBN
cord-264699-l8db5gll	129	7	levels	level	NNS
cord-264699-l8db5gll	129	8	of	of	IN
cord-264699-l8db5gll	129	9	TAFII-17	tafii-17	CD
cord-264699-l8db5gll	129	10	,	,	,
cord-264699-l8db5gll	129	11	which	which	WDT
cord-264699-l8db5gll	129	12	is	be	VBZ
cord-264699-l8db5gll	129	13	one	one	CD
cord-264699-l8db5gll	129	14	of	of	IN
cord-264699-l8db5gll	129	15	the	the	DT
cord-264699-l8db5gll	129	16	components	component	NNS
cord-264699-l8db5gll	129	17	of	of	IN
cord-264699-l8db5gll	129	18	the	the	DT
cord-264699-l8db5gll	129	19	general	general	JJ
cord-264699-l8db5gll	129	20	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	129	21	complexes	complex	NNS
cord-264699-l8db5gll	129	22	that	that	WDT
cord-264699-l8db5gll	129	23	are	be	VBP
cord-264699-l8db5gll	129	24	attracted	attract	VBN
cord-264699-l8db5gll	129	25	to	to	IN
cord-264699-l8db5gll	129	26	the	the	DT
cord-264699-l8db5gll	129	27	ligand	ligand	NN
cord-264699-l8db5gll	129	28	-	-	HYPH
cord-264699-l8db5gll	129	29	activated	activate	VBN
cord-264699-l8db5gll	129	30	vitamin	vitamin	NN
cord-264699-l8db5gll	129	31	D	d	NN
cord-264699-l8db5gll	129	32	receptor	receptor	NN
cord-264699-l8db5gll	129	33	[	[	-LRB-
cord-264699-l8db5gll	129	34	40	40	CD
cord-264699-l8db5gll	129	35	]	]	-RRB-
cord-264699-l8db5gll	129	36	.	.	.
cord-264699-l8db5gll	130	1	Thus	thus	RB
cord-264699-l8db5gll	130	2	,	,	,
cord-264699-l8db5gll	130	3	it	-PRON-	PRP
cord-264699-l8db5gll	130	4	is	be	VBZ
cord-264699-l8db5gll	130	5	possible	possible	JJ
cord-264699-l8db5gll	130	6	that	that	IN
cord-264699-l8db5gll	130	7	Paget	Paget	NNP
cord-264699-l8db5gll	130	8	's	's	POS
cord-264699-l8db5gll	130	9	disease	disease	NN
cord-264699-l8db5gll	130	10	of	of	IN
cord-264699-l8db5gll	130	11	bone	bone	NN
cord-264699-l8db5gll	130	12	might	may	MD
cord-264699-l8db5gll	130	13	be	be	VB
cord-264699-l8db5gll	130	14	caused	cause	VBN
cord-264699-l8db5gll	130	15	,	,	,
cord-264699-l8db5gll	130	16	in	in	IN
cord-264699-l8db5gll	130	17	part	part	NN
cord-264699-l8db5gll	130	18	,	,	,
cord-264699-l8db5gll	130	19	by	by	IN
cord-264699-l8db5gll	130	20	the	the	DT
cord-264699-l8db5gll	130	21	measles	measle	NNS
cord-264699-l8db5gll	130	22	virus	virus	NN
cord-264699-l8db5gll	130	23	,	,	,
cord-264699-l8db5gll	130	24	through	through	IN
cord-264699-l8db5gll	130	25	its	-PRON-	PRP$
cord-264699-l8db5gll	130	26	encoded	encoded	JJ
cord-264699-l8db5gll	130	27	molecule	molecule	NN
cord-264699-l8db5gll	130	28	MVNP	MVNP	NNP
cord-264699-l8db5gll	130	29	increasing	increase	VBG
cord-264699-l8db5gll	130	30	the	the	DT
cord-264699-l8db5gll	130	31	sensitivity	sensitivity	NN
cord-264699-l8db5gll	130	32	of	of	IN
cord-264699-l8db5gll	130	33	osteoclasts	osteoclast	NNS
cord-264699-l8db5gll	130	34	to	to	IN
cord-264699-l8db5gll	130	35	vitamin	vitamin	NN
cord-264699-l8db5gll	130	36	D.	D.	NNP
cord-264699-l8db5gll	130	37	Possible	possible	JJ
cord-264699-l8db5gll	130	38	alteration	alteration	NN
cord-264699-l8db5gll	130	39	of	of	IN
cord-264699-l8db5gll	130	40	endocrine	endocrine	JJ
cord-264699-l8db5gll	130	41	system	system	NN
cord-264699-l8db5gll	130	42	by	by	IN
cord-264699-l8db5gll	130	43	Adenovirus	Adenovirus	NNP
cord-264699-l8db5gll	130	44	E1A	e1a	NN
cord-264699-l8db5gll	130	45	protein	protein	NN
cord-264699-l8db5gll	131	1	Adenoviruses	adenovirus	NNS
cord-264699-l8db5gll	131	2	are	be	VBP
cord-264699-l8db5gll	131	3	the	the	DT
cord-264699-l8db5gll	131	4	double	double	JJ
cord-264699-l8db5gll	131	5	strand	strand	NN
cord-264699-l8db5gll	131	6	DNA	dna	NN
cord-264699-l8db5gll	131	7	viruses	virus	NNS
cord-264699-l8db5gll	131	8	of	of	IN
cord-264699-l8db5gll	131	9	the	the	DT
cord-264699-l8db5gll	131	10	Adenoviridae	Adenoviridae	NNP
cord-264699-l8db5gll	131	11	family	family	NN
cord-264699-l8db5gll	131	12	.	.	.
cord-264699-l8db5gll	132	1	This	this	DT
cord-264699-l8db5gll	132	2	group	group	NN
cord-264699-l8db5gll	132	3	of	of	IN
cord-264699-l8db5gll	132	4	viruses	virus	NNS
cord-264699-l8db5gll	132	5	causes	cause	VBZ
cord-264699-l8db5gll	132	6	illness	illness	NN
cord-264699-l8db5gll	132	7	of	of	IN
cord-264699-l8db5gll	132	8	the	the	DT
cord-264699-l8db5gll	132	9	respiratory	respiratory	JJ
cord-264699-l8db5gll	132	10	system	system	NN
cord-264699-l8db5gll	132	11	,	,	,
cord-264699-l8db5gll	132	12	such	such	JJ
cord-264699-l8db5gll	132	13	as	as	IN
cord-264699-l8db5gll	132	14	common	common	JJ
cord-264699-l8db5gll	132	15	cold	cold	JJ
cord-264699-l8db5gll	132	16	syndrome	syndrome	NN
cord-264699-l8db5gll	132	17	,	,	,
cord-264699-l8db5gll	132	18	pneumonia	pneumonia	NN
cord-264699-l8db5gll	132	19	,	,	,
cord-264699-l8db5gll	132	20	croup	croup	NN
cord-264699-l8db5gll	132	21	and	and	CC
cord-264699-l8db5gll	132	22	bronchitis	bronchitis	NN
cord-264699-l8db5gll	132	23	,	,	,
cord-264699-l8db5gll	132	24	as	as	RB
cord-264699-l8db5gll	132	25	well	well	RB
cord-264699-l8db5gll	132	26	as	as	IN
cord-264699-l8db5gll	132	27	illnesses	illness	NNS
cord-264699-l8db5gll	132	28	of	of	IN
cord-264699-l8db5gll	132	29	other	other	JJ
cord-264699-l8db5gll	132	30	organs	organ	NNS
cord-264699-l8db5gll	132	31	,	,	,
cord-264699-l8db5gll	132	32	such	such	JJ
cord-264699-l8db5gll	132	33	as	as	IN
cord-264699-l8db5gll	132	34	gastroenteritis	gastroenteritis	NN
cord-264699-l8db5gll	132	35	,	,	,
cord-264699-l8db5gll	132	36	conjunctivitis	conjunctivitis	NN
cord-264699-l8db5gll	132	37	and	and	CC
cord-264699-l8db5gll	132	38	cystitis	cystitis	NN
cord-264699-l8db5gll	132	39	[	[	-LRB-
cord-264699-l8db5gll	132	40	43	43	CD
cord-264699-l8db5gll	132	41	]	]	-RRB-
cord-264699-l8db5gll	132	42	.	.	.
cord-264699-l8db5gll	133	1	Adenoviruses	adenovirus	NNS
cord-264699-l8db5gll	133	2	encode	encode	VBP
cord-264699-l8db5gll	133	3	the	the	DT
cord-264699-l8db5gll	133	4	E1A	e1a	NN
cord-264699-l8db5gll	133	5	protein	protein	NN
cord-264699-l8db5gll	133	6	,	,	,
cord-264699-l8db5gll	133	7	which	which	WDT
cord-264699-l8db5gll	133	8	is	be	VBZ
cord-264699-l8db5gll	133	9	expressed	express	VBN
cord-264699-l8db5gll	133	10	just	just	RB
cord-264699-l8db5gll	133	11	after	after	IN
cord-264699-l8db5gll	133	12	infection	infection	NN
cord-264699-l8db5gll	133	13	and	and	CC
cord-264699-l8db5gll	133	14	is	be	VBZ
cord-264699-l8db5gll	133	15	necessary	necessary	JJ
cord-264699-l8db5gll	133	16	for	for	IN
cord-264699-l8db5gll	133	17	the	the	DT
cord-264699-l8db5gll	133	18	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	133	19	regulation	regulation	NN
cord-264699-l8db5gll	133	20	of	of	IN
cord-264699-l8db5gll	133	21	adenovirus	adenovirus	NN
cord-264699-l8db5gll	133	22	-	-	HYPH
cord-264699-l8db5gll	133	23	encoded	encode	VBN
cord-264699-l8db5gll	133	24	genes	gene	NNS
cord-264699-l8db5gll	133	25	[	[	-LRB-
cord-264699-l8db5gll	133	26	43	43	CD
cord-264699-l8db5gll	133	27	]	]	-RRB-
cord-264699-l8db5gll	133	28	.	.	.
cord-264699-l8db5gll	134	1	In	in	IN
cord-264699-l8db5gll	134	2	addition	addition	NN
cord-264699-l8db5gll	134	3	to	to	IN
cord-264699-l8db5gll	134	4	viral	viral	JJ
cord-264699-l8db5gll	134	5	genes	gene	NNS
cord-264699-l8db5gll	134	6	,	,	,
cord-264699-l8db5gll	134	7	E1A	E1A	NNP
cord-264699-l8db5gll	134	8	regulates	regulate	VBZ
cord-264699-l8db5gll	134	9	the	the	DT
cord-264699-l8db5gll	134	10	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	134	11	activity	activity	NN
cord-264699-l8db5gll	134	12	of	of	IN
cord-264699-l8db5gll	134	13	several	several	JJ
cord-264699-l8db5gll	134	14	host	host	NN
cord-264699-l8db5gll	134	15	genes	gene	NNS
cord-264699-l8db5gll	134	16	through	through	IN
cord-264699-l8db5gll	134	17	interaction	interaction	NN
cord-264699-l8db5gll	134	18	with	with	IN
cord-264699-l8db5gll	134	19	the	the	DT
cord-264699-l8db5gll	134	20	host	host	NN
cord-264699-l8db5gll	134	21	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	134	22	integrator	integrator	NN
cord-264699-l8db5gll	134	23	p300	p300	NNP
cord-264699-l8db5gll	134	24	and	and	CC
cord-264699-l8db5gll	134	25	its	-PRON-	PRP$
cord-264699-l8db5gll	134	26	homologous	homologous	JJ
cord-264699-l8db5gll	134	27	molecule	molecule	NN
cord-264699-l8db5gll	134	28	CBP	CBP	NNP
cord-264699-l8db5gll	134	29	(	(	-LRB-
cord-264699-l8db5gll	134	30	Figure	figure	NN
cord-264699-l8db5gll	134	31	2	2	CD
cord-264699-l8db5gll	134	32	)	)	-RRB-
cord-264699-l8db5gll	134	33	[	[	-LRB-
cord-264699-l8db5gll	134	34	33	33	CD
cord-264699-l8db5gll	134	35	,	,	,
cord-264699-l8db5gll	134	36	44	44	CD
cord-264699-l8db5gll	134	37	]	]	-RRB-
cord-264699-l8db5gll	134	38	.	.	.
cord-264699-l8db5gll	135	1	In	in	IN
cord-264699-l8db5gll	135	2	an	an	DT
cord-264699-l8db5gll	135	3	in	in	FW
cord-264699-l8db5gll	135	4	vitro	vitro	FW
cord-264699-l8db5gll	135	5	system	system	NN
cord-264699-l8db5gll	135	6	,	,	,
cord-264699-l8db5gll	135	7	E1A	E1A	NNP
cord-264699-l8db5gll	135	8	,	,	,
cord-264699-l8db5gll	135	9	in	in	IN
cord-264699-l8db5gll	135	10	contrast	contrast	NN
cord-264699-l8db5gll	135	11	to	to	IN
cord-264699-l8db5gll	135	12	Vpr	Vpr	NNP
cord-264699-l8db5gll	135	13	,	,	,
cord-264699-l8db5gll	135	14	blocks	block	VBZ
cord-264699-l8db5gll	135	15	the	the	DT
cord-264699-l8db5gll	135	16	actions	action	NNS
cord-264699-l8db5gll	135	17	of	of	IN
cord-264699-l8db5gll	135	18	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	135	19	on	on	IN
cord-264699-l8db5gll	135	20	the	the	DT
cord-264699-l8db5gll	135	21	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	135	22	activity	activity	NN
cord-264699-l8db5gll	135	23	of	of	IN
cord-264699-l8db5gll	135	24	genes	gene	NNS
cord-264699-l8db5gll	135	25	,	,	,
cord-264699-l8db5gll	135	26	producing	produce	VBG
cord-264699-l8db5gll	135	27	resistance	resistance	NN
cord-264699-l8db5gll	135	28	to	to	IN
cord-264699-l8db5gll	135	29	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	135	30	[	[	-LRB-
cord-264699-l8db5gll	135	31	30	30	CD
cord-264699-l8db5gll	135	32	]	]	-RRB-
cord-264699-l8db5gll	135	33	.	.	.
cord-264699-l8db5gll	136	1	E1A	E1A	NNP
cord-264699-l8db5gll	136	2	also	also	RB
cord-264699-l8db5gll	136	3	interacts	interact	VBZ
cord-264699-l8db5gll	136	4	with	with	IN
cord-264699-l8db5gll	136	5	the	the	DT
cord-264699-l8db5gll	136	6	C	c	NN
cord-264699-l8db5gll	136	7	-	-	HYPH
cord-264699-l8db5gll	136	8	terminal	terminal	NN
cord-264699-l8db5gll	136	9	tail	tail	NN
cord-264699-l8db5gll	136	10	-	-	HYPH
cord-264699-l8db5gll	136	11	binding	bind	VBG
cord-264699-l8db5gll	136	12	protein	protein	NN
cord-264699-l8db5gll	136	13	(	(	-LRB-
cord-264699-l8db5gll	136	14	CtBP	CtBP	NNP
cord-264699-l8db5gll	136	15	)	)	-RRB-
cord-264699-l8db5gll	136	16	,	,	,
cord-264699-l8db5gll	136	17	which	which	WDT
cord-264699-l8db5gll	136	18	functions	function	VBZ
cord-264699-l8db5gll	136	19	as	as	IN
cord-264699-l8db5gll	136	20	a	a	DT
cord-264699-l8db5gll	136	21	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	136	22	repressor	repressor	NN
cord-264699-l8db5gll	136	23	of	of	IN
cord-264699-l8db5gll	136	24	numerous	numerous	JJ
cord-264699-l8db5gll	136	25	transcription	transcription	NN
cord-264699-l8db5gll	136	26	factors	factor	NNS
cord-264699-l8db5gll	136	27	by	by	IN
cord-264699-l8db5gll	136	28	communicating	communicate	VBG
cord-264699-l8db5gll	136	29	with	with	IN
cord-264699-l8db5gll	136	30	class	class	NN
cord-264699-l8db5gll	136	31	II	II	NNP
cord-264699-l8db5gll	136	32	histone	histone	NN
cord-264699-l8db5gll	136	33	deacetylases	deacetylase	NNS
cord-264699-l8db5gll	136	34	and	and	CC
cord-264699-l8db5gll	136	35	other	other	JJ
cord-264699-l8db5gll	136	36	inhibitory	inhibitory	JJ
cord-264699-l8db5gll	136	37	molecules	molecule	NNS
cord-264699-l8db5gll	136	38	,	,	,
cord-264699-l8db5gll	136	39	such	such	JJ
cord-264699-l8db5gll	136	40	as	as	IN
cord-264699-l8db5gll	136	41	the	the	DT
cord-264699-l8db5gll	136	42	retinoblastoma	retinoblastoma	NN
cord-264699-l8db5gll	136	43	protein	protein	NN
cord-264699-l8db5gll	136	44	(	(	-LRB-
cord-264699-l8db5gll	136	45	Rb	Rb	NNP
cord-264699-l8db5gll	136	46	)	)	-RRB-
cord-264699-l8db5gll	137	1	(	(	-LRB-
cord-264699-l8db5gll	137	2	Figure	figure	NN
cord-264699-l8db5gll	137	3	2	2	CD
cord-264699-l8db5gll	137	4	)	)	-RRB-
cord-264699-l8db5gll	137	5	[	[	-LRB-
cord-264699-l8db5gll	137	6	45	45	CD
cord-264699-l8db5gll	137	7	]	]	-RRB-
cord-264699-l8db5gll	137	8	.	.	.
cord-264699-l8db5gll	138	1	E1A	E1A	NNP
cord-264699-l8db5gll	138	2	suppresses	suppress	VBZ
cord-264699-l8db5gll	138	3	the	the	DT
cord-264699-l8db5gll	138	4	activity	activity	NN
cord-264699-l8db5gll	138	5	of	of	IN
cord-264699-l8db5gll	138	6	p300	p300	NNP
cord-264699-l8db5gll	138	7	/	/	SYM
cord-264699-l8db5gll	138	8	CBP	CBP	NNP
cord-264699-l8db5gll	138	9	and	and	CC
cord-264699-l8db5gll	138	10	CtBP	CtBP	NNP
cord-264699-l8db5gll	138	11	by	by	IN
cord-264699-l8db5gll	138	12	binding	bind	VBG
cord-264699-l8db5gll	138	13	to	to	IN
cord-264699-l8db5gll	138	14	functionally	functionally	RB
cord-264699-l8db5gll	138	15	crucial	crucial	JJ
cord-264699-l8db5gll	138	16	domains	domain	NNS
cord-264699-l8db5gll	138	17	[	[	-LRB-
cord-264699-l8db5gll	138	18	33	33	CD
cord-264699-l8db5gll	138	19	,	,	,
cord-264699-l8db5gll	138	20	45	45	CD
cord-264699-l8db5gll	138	21	]	]	-RRB-
cord-264699-l8db5gll	138	22	.	.	.
cord-264699-l8db5gll	139	1	Although	although	IN
cord-264699-l8db5gll	139	2	there	there	EX
cord-264699-l8db5gll	139	3	is	be	VBZ
cord-264699-l8db5gll	139	4	no	no	DT
cord-264699-l8db5gll	139	5	supportive	supportive	JJ
cord-264699-l8db5gll	139	6	clinical	clinical	JJ
cord-264699-l8db5gll	139	7	evidence	evidence	NN
cord-264699-l8db5gll	139	8	,	,	,
cord-264699-l8db5gll	139	9	it	-PRON-	PRP
cord-264699-l8db5gll	139	10	is	be	VBZ
cord-264699-l8db5gll	139	11	possible	possible	JJ
cord-264699-l8db5gll	139	12	that	that	IN
cord-264699-l8db5gll	139	13	adenovirus	adenovirus	NN
cord-264699-l8db5gll	139	14	changes	change	VBZ
cord-264699-l8db5gll	139	15	the	the	DT
cord-264699-l8db5gll	139	16	peripheral	peripheral	JJ
cord-264699-l8db5gll	139	17	action	action	NN
cord-264699-l8db5gll	139	18	of	of	IN
cord-264699-l8db5gll	139	19	circulating	circulate	VBG
cord-264699-l8db5gll	139	20	hormones	hormone	NNS
cord-264699-l8db5gll	139	21	,	,	,
cord-264699-l8db5gll	139	22	such	such	JJ
cord-264699-l8db5gll	139	23	as	as	IN
cord-264699-l8db5gll	139	24	glucocorticoids	glucocorticoid	NNS
cord-264699-l8db5gll	139	25	and	and	CC
cord-264699-l8db5gll	139	26	other	other	JJ
cord-264699-l8db5gll	139	27	bioactive	bioactive	JJ
cord-264699-l8db5gll	139	28	molecules	molecule	NNS
cord-264699-l8db5gll	139	29	that	that	WDT
cord-264699-l8db5gll	139	30	activate	activate	VBP
cord-264699-l8db5gll	139	31	NRs	nr	NNS
cord-264699-l8db5gll	139	32	and	and	CC
cord-264699-l8db5gll	139	33	directly	directly	RB
cord-264699-l8db5gll	139	34	regulate	regulate	VB
cord-264699-l8db5gll	139	35	the	the	DT
cord-264699-l8db5gll	139	36	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	139	37	activity	activity	NN
cord-264699-l8db5gll	139	38	of	of	IN
cord-264699-l8db5gll	139	39	their	-PRON-	PRP$
cord-264699-l8db5gll	139	40	target	target	NN
cord-264699-l8db5gll	139	41	genes	gene	NNS
cord-264699-l8db5gll	139	42	,	,	,
cord-264699-l8db5gll	139	43	ultimately	ultimately	RB
cord-264699-l8db5gll	139	44	contributing	contribute	VBG
cord-264699-l8db5gll	139	45	to	to	IN
cord-264699-l8db5gll	139	46	the	the	DT
cord-264699-l8db5gll	139	47	pathological	pathological	JJ
cord-264699-l8db5gll	139	48	states	state	NNS
cord-264699-l8db5gll	139	49	observed	observe	VBN
cord-264699-l8db5gll	139	50	in	in	IN
cord-264699-l8db5gll	139	51	adenoviral	adenoviral	JJ
cord-264699-l8db5gll	139	52	infection	infection	NN
cord-264699-l8db5gll	139	53	.	.	.
cord-264699-l8db5gll	140	1	In	in	IN
cord-264699-l8db5gll	140	2	2003	2003	CD
cord-264699-l8db5gll	140	3	,	,	,
cord-264699-l8db5gll	140	4	the	the	DT
cord-264699-l8db5gll	140	5	virus	virus	NN
cord-264699-l8db5gll	140	6	that	that	WDT
cord-264699-l8db5gll	140	7	caused	cause	VBD
cord-264699-l8db5gll	140	8	a	a	DT
cord-264699-l8db5gll	140	9	newly	newly	RB
cord-264699-l8db5gll	140	10	identified	identify	VBN
cord-264699-l8db5gll	140	11	illness	illness	NN
cord-264699-l8db5gll	140	12	called	call	VBN
cord-264699-l8db5gll	140	13	SARS	SARS	NNP
cord-264699-l8db5gll	140	14	spread	spread	VBD
cord-264699-l8db5gll	140	15	rapidly	rapidly	RB
cord-264699-l8db5gll	140	16	worldwide	worldwide	RB
cord-264699-l8db5gll	140	17	,	,	,
cord-264699-l8db5gll	140	18	causing	cause	VBG
cord-264699-l8db5gll	140	19	almost	almost	RB
cord-264699-l8db5gll	140	20	800	800	CD
cord-264699-l8db5gll	140	21	deaths	death	NNS
cord-264699-l8db5gll	140	22	[	[	-LRB-
cord-264699-l8db5gll	140	23	3	3	CD
cord-264699-l8db5gll	140	24	,	,	,
cord-264699-l8db5gll	140	25	46	46	CD
cord-264699-l8db5gll	140	26	]	]	-RRB-
cord-264699-l8db5gll	140	27	.	.	.
cord-264699-l8db5gll	141	1	SARS	SARS	NNP
cord-264699-l8db5gll	141	2	starts	start	VBZ
cord-264699-l8db5gll	141	3	with	with	IN
cord-264699-l8db5gll	141	4	flu	flu	NN
cord-264699-l8db5gll	141	5	-	-	HYPH
cord-264699-l8db5gll	141	6	like	like	JJ
cord-264699-l8db5gll	141	7	symptoms	symptom	NNS
cord-264699-l8db5gll	141	8	,	,	,
cord-264699-l8db5gll	141	9	such	such	JJ
cord-264699-l8db5gll	141	10	as	as	IN
cord-264699-l8db5gll	141	11	fever	fever	NN
cord-264699-l8db5gll	141	12	,	,	,
cord-264699-l8db5gll	141	13	myalgia	myalgia	NN
cord-264699-l8db5gll	141	14	,	,	,
cord-264699-l8db5gll	141	15	somnolence	somnolence	NN
cord-264699-l8db5gll	141	16	,	,	,
cord-264699-l8db5gll	141	17	gastrointestinal	gastrointestinal	JJ
cord-264699-l8db5gll	141	18	symptoms	symptom	NNS
cord-264699-l8db5gll	141	19	,	,	,
cord-264699-l8db5gll	141	20	cough	cough	NN
cord-264699-l8db5gll	141	21	and	and	CC
cord-264699-l8db5gll	141	22	sore	sore	JJ
cord-264699-l8db5gll	141	23	throat	throat	NN
cord-264699-l8db5gll	141	24	,	,	,
cord-264699-l8db5gll	141	25	and	and	CC
cord-264699-l8db5gll	141	26	eventually	eventually	RB
cord-264699-l8db5gll	141	27	develops	develop	VBZ
cord-264699-l8db5gll	141	28	into	into	IN
cord-264699-l8db5gll	141	29	pneumonia	pneumonia	NN
cord-264699-l8db5gll	141	30	with	with	IN
cord-264699-l8db5gll	141	31	severe	severe	JJ
cord-264699-l8db5gll	141	32	respiratory	respiratory	JJ
cord-264699-l8db5gll	141	33	failure	failure	NN
cord-264699-l8db5gll	141	34	[	[	-LRB-
cord-264699-l8db5gll	141	35	3	3	CD
cord-264699-l8db5gll	141	36	,	,	,
cord-264699-l8db5gll	141	37	46	46	CD
cord-264699-l8db5gll	141	38	]	]	-RRB-
cord-264699-l8db5gll	141	39	.	.	.
cord-264699-l8db5gll	142	1	Mechanical	mechanical	JJ
cord-264699-l8db5gll	142	2	ventilation	ventilation	NN
cord-264699-l8db5gll	142	3	is	be	VBZ
cord-264699-l8db5gll	142	4	required	require	VBN
cord-264699-l8db5gll	142	5	in	in	IN
cord-264699-l8db5gll	142	6	$	$	$
cord-264699-l8db5gll	142	7	10	10	CD
cord-264699-l8db5gll	142	8	-	-	SYM
cord-264699-l8db5gll	142	9	20	20	CD
cord-264699-l8db5gll	142	10	%	%	NN
cord-264699-l8db5gll	142	11	of	of	IN
cord-264699-l8db5gll	142	12	cases	case	NNS
cord-264699-l8db5gll	142	13	and	and	CC
cord-264699-l8db5gll	142	14	the	the	DT
cord-264699-l8db5gll	142	15	death	death	NN
cord-264699-l8db5gll	142	16	rate	rate	NN
cord-264699-l8db5gll	142	17	is	be	VBZ
cord-264699-l8db5gll	142	18	almost	almost	RB
cord-264699-l8db5gll	142	19	10	10	CD
cord-264699-l8db5gll	142	20	%	%	NN
cord-264699-l8db5gll	142	21	[	[	-LRB-
cord-264699-l8db5gll	142	22	3	3	CD
cord-264699-l8db5gll	142	23	,	,	,
cord-264699-l8db5gll	142	24	46	46	CD
cord-264699-l8db5gll	142	25	]	]	-RRB-
cord-264699-l8db5gll	142	26	.	.	.
cord-264699-l8db5gll	143	1	The	the	DT
cord-264699-l8db5gll	143	2	causative	causative	JJ
cord-264699-l8db5gll	143	3	virus	virus	NN
cord-264699-l8db5gll	143	4	of	of	IN
cord-264699-l8db5gll	143	5	this	this	DT
cord-264699-l8db5gll	143	6	severe	severe	JJ
cord-264699-l8db5gll	143	7	respiratory	respiratory	JJ
cord-264699-l8db5gll	143	8	syndrome	syndrome	NN
cord-264699-l8db5gll	143	9	is	be	VBZ
cord-264699-l8db5gll	143	10	the	the	DT
cord-264699-l8db5gll	143	11	SARS	SARS	NNP
cord-264699-l8db5gll	143	12	coronavirus	coronavirus	NN
cord-264699-l8db5gll	143	13	(	(	-LRB-
cord-264699-l8db5gll	143	14	SARS	SARS	NNP
cord-264699-l8db5gll	143	15	-	-	HYPH
cord-264699-l8db5gll	143	16	CoV	CoV	NNP
cord-264699-l8db5gll	143	17	)	)	-RRB-
cord-264699-l8db5gll	143	18	,	,	,
cord-264699-l8db5gll	143	19	a	a	DT
cord-264699-l8db5gll	143	20	positive	positive	JJ
cord-264699-l8db5gll	143	21	single	single	JJ
cord-264699-l8db5gll	143	22	-	-	HYPH
cord-264699-l8db5gll	143	23	strand	strand	NN
cord-264699-l8db5gll	143	24	RNA	RNA	NNP
cord-264699-l8db5gll	143	25	virus	virus	NN
cord-264699-l8db5gll	143	26	of	of	IN
cord-264699-l8db5gll	143	27	the	the	DT
cord-264699-l8db5gll	143	28	Coronaviridae	Coronaviridae	NNP
cord-264699-l8db5gll	143	29	family	family	NN
cord-264699-l8db5gll	143	30	[	[	-LRB-
cord-264699-l8db5gll	143	31	47	47	CD
cord-264699-l8db5gll	143	32	]	]	-RRB-
cord-264699-l8db5gll	143	33	.	.	.
cord-264699-l8db5gll	144	1	Subsequently	subsequently	RB
cord-264699-l8db5gll	144	2	,	,	,
cord-264699-l8db5gll	144	3	the	the	DT
cord-264699-l8db5gll	144	4	angiotensin	angiotensin	NN
cord-264699-l8db5gll	144	5	-	-	HYPH
cord-264699-l8db5gll	144	6	converting	convert	VBG
cord-264699-l8db5gll	144	7	enzyme	enzyme	NN
cord-264699-l8db5gll	144	8	2	2	CD
cord-264699-l8db5gll	144	9	(	(	-LRB-
cord-264699-l8db5gll	144	10	ACE2	ACE2	NNP
cord-264699-l8db5gll	144	11	)	)	-RRB-
cord-264699-l8db5gll	144	12	was	be	VBD
cord-264699-l8db5gll	144	13	identified	identify	VBN
cord-264699-l8db5gll	144	14	as	as	IN
cord-264699-l8db5gll	144	15	a	a	DT
cord-264699-l8db5gll	144	16	cellular	cellular	JJ
cord-264699-l8db5gll	144	17	receptor	receptor	NN
cord-264699-l8db5gll	144	18	for	for	IN
cord-264699-l8db5gll	144	19	the	the	DT
cord-264699-l8db5gll	144	20	entry	entry	NN
cord-264699-l8db5gll	144	21	of	of	IN
cord-264699-l8db5gll	144	22	this	this	DT
cord-264699-l8db5gll	144	23	virus	virus	NN
cord-264699-l8db5gll	144	24	[	[	-LRB-
cord-264699-l8db5gll	144	25	48	48	CD
cord-264699-l8db5gll	144	26	]	]	-RRB-
cord-264699-l8db5gll	144	27	.	.	.
cord-264699-l8db5gll	145	1	ACE2	ACE2	NNP
cord-264699-l8db5gll	145	2	was	be	VBD
cord-264699-l8db5gll	145	3	first	first	RB
cord-264699-l8db5gll	145	4	cloned	clone	VBN
cord-264699-l8db5gll	145	5	as	as	IN
cord-264699-l8db5gll	145	6	a	a	DT
cord-264699-l8db5gll	145	7	homolog	homolog	NN
cord-264699-l8db5gll	145	8	of	of	IN
cord-264699-l8db5gll	145	9	ACE	ace	NN
cord-264699-l8db5gll	145	10	in	in	IN
cord-264699-l8db5gll	145	11	2000	2000	CD
cord-264699-l8db5gll	145	12	[	[	-LRB-
cord-264699-l8db5gll	145	13	49	49	CD
cord-264699-l8db5gll	145	14	,	,	,
cord-264699-l8db5gll	145	15	50	50	CD
cord-264699-l8db5gll	145	16	]	]	-RRB-
cord-264699-l8db5gll	145	17	.	.	.
cord-264699-l8db5gll	146	1	Although	although	IN
cord-264699-l8db5gll	146	2	it	-PRON-	PRP
cord-264699-l8db5gll	146	3	functions	function	VBZ
cord-264699-l8db5gll	146	4	as	as	IN
cord-264699-l8db5gll	146	5	a	a	DT
cord-264699-l8db5gll	146	6	carboxypeptidase	carboxypeptidase	NN
cord-264699-l8db5gll	146	7	similar	similar	JJ
cord-264699-l8db5gll	146	8	to	to	IN
cord-264699-l8db5gll	146	9	ACE	ACE	NNP
cord-264699-l8db5gll	146	10	,	,	,
cord-264699-l8db5gll	146	11	it	-PRON-	PRP
cord-264699-l8db5gll	146	12	has	have	VBZ
cord-264699-l8db5gll	146	13	different	different	JJ
cord-264699-l8db5gll	146	14	substrate	substrate	NN
cord-264699-l8db5gll	146	15	specificity	specificity	NN
cord-264699-l8db5gll	146	16	:	:	:
cord-264699-l8db5gll	147	1	ACE2	ACE2	NNP
cord-264699-l8db5gll	147	2	cleaves	cleave	VBZ
cord-264699-l8db5gll	147	3	a	a	DT
cord-264699-l8db5gll	147	4	single	single	JJ
cord-264699-l8db5gll	147	5	residue	residue	NN
cord-264699-l8db5gll	147	6	from	from	IN
cord-264699-l8db5gll	147	7	angiotensin	angiotensin	NN
cord-264699-l8db5gll	148	1	I	-PRON-	PRP
cord-264699-l8db5gll	148	2	(	(	-LRB-
cord-264699-l8db5gll	148	3	ANG	ANG	NNP
cord-264699-l8db5gll	148	4	I	I	NNP
cord-264699-l8db5gll	148	5	)	)	-RRB-
cord-264699-l8db5gll	148	6	and	and	CC
cord-264699-l8db5gll	148	7	ANG	ANG	NNP
cord-264699-l8db5gll	148	8	II	II	NNP
cord-264699-l8db5gll	148	9	to	to	TO
cord-264699-l8db5gll	148	10	generate	generate	VB
cord-264699-l8db5gll	148	11	the	the	DT
cord-264699-l8db5gll	148	12	inactive	inactive	JJ
cord-264699-l8db5gll	148	13	forms	form	NNS
cord-264699-l8db5gll	148	14	angiotensin	angiotensin	NN
cord-264699-l8db5gll	148	15	(	(	-LRB-
cord-264699-l8db5gll	148	16	1	1	CD
cord-264699-l8db5gll	148	17	-	-	SYM
cord-264699-l8db5gll	148	18	9	9	CD
cord-264699-l8db5gll	148	19	)	)	-RRB-
cord-264699-l8db5gll	148	20	and	and	CC
cord-264699-l8db5gll	148	21	angiotensin	angiotensin	NN
cord-264699-l8db5gll	148	22	(	(	-LRB-
cord-264699-l8db5gll	148	23	1	1	CD
cord-264699-l8db5gll	148	24	-	-	SYM
cord-264699-l8db5gll	148	25	7	7	CD
cord-264699-l8db5gll	148	26	)	)	-RRB-
cord-264699-l8db5gll	148	27	,	,	,
cord-264699-l8db5gll	148	28	respectively	respectively	RB
cord-264699-l8db5gll	148	29	,	,	,
cord-264699-l8db5gll	148	30	whereas	whereas	IN
cord-264699-l8db5gll	148	31	ACE	ACE	NNP
cord-264699-l8db5gll	148	32	removes	remove	VBZ
cord-264699-l8db5gll	148	33	dipeptides	dipeptide	NNS
cord-264699-l8db5gll	148	34	from	from	IN
cord-264699-l8db5gll	148	35	the	the	DT
cord-264699-l8db5gll	148	36	C	C	NNP
cord-264699-l8db5gll	148	37	-	-	HYPH
cord-264699-l8db5gll	148	38	terminus	terminus	NN
cord-264699-l8db5gll	148	39	of	of	IN
cord-264699-l8db5gll	148	40	ANG	ANG	NNP
cord-264699-l8db5gll	148	41	I	-PRON-	PRP
cord-264699-l8db5gll	148	42	to	to	TO
cord-264699-l8db5gll	148	43	produce	produce	VB
cord-264699-l8db5gll	148	44	potent	potent	JJ
cord-264699-l8db5gll	148	45	,	,	,
cord-264699-l8db5gll	148	46	bioactive	bioactive	JJ
cord-264699-l8db5gll	148	47	ANG	ANG	NNP
cord-264699-l8db5gll	148	48	II	II	NNP
cord-264699-l8db5gll	148	49	(	(	-LRB-
cord-264699-l8db5gll	148	50	Figure	figure	NN
cord-264699-l8db5gll	148	51	4	4	CD
cord-264699-l8db5gll	148	52	)	)	-RRB-
cord-264699-l8db5gll	149	1	[	[	-LRB-
cord-264699-l8db5gll	149	2	51	51	CD
cord-264699-l8db5gll	149	3	]	]	-RRB-
cord-264699-l8db5gll	149	4	.	.	.
cord-264699-l8db5gll	150	1	From	from	IN
cord-264699-l8db5gll	150	2	mouse	mouse	NN
cord-264699-l8db5gll	150	3	knockout	knockout	NN
cord-264699-l8db5gll	150	4	studies	study	NNS
cord-264699-l8db5gll	150	5	,	,	,
cord-264699-l8db5gll	150	6	ACE2	ACE2	NNP
cord-264699-l8db5gll	150	7	is	be	VBZ
cord-264699-l8db5gll	150	8	a	a	DT
cord-264699-l8db5gll	150	9	negative	negative	JJ
cord-264699-l8db5gll	150	10	regulator	regulator	NN
cord-264699-l8db5gll	150	11	of	of	IN
cord-264699-l8db5gll	150	12	the	the	DT
cord-264699-l8db5gll	150	13	rennin	rennin	NN
cord-264699-l8db5gll	150	14	-	-	HYPH
cord-264699-l8db5gll	150	15	angiotensin	angiotensin	NN
cord-264699-l8db5gll	150	16	system	system	NN
cord-264699-l8db5gll	150	17	that	that	WDT
cord-264699-l8db5gll	150	18	counterbalances	counterbalance	VBZ
cord-264699-l8db5gll	150	19	the	the	DT
cord-264699-l8db5gll	150	20	function	function	NN
cord-264699-l8db5gll	150	21	of	of	IN
cord-264699-l8db5gll	150	22	ACE	ace	NN
cord-264699-l8db5gll	150	23	[	[	-LRB-
cord-264699-l8db5gll	150	24	52	52	CD
cord-264699-l8db5gll	150	25	]	]	-RRB-
cord-264699-l8db5gll	150	26	.	.	.
cord-264699-l8db5gll	151	1	ANG	ANG	NNP
cord-264699-l8db5gll	151	2	II	II	NNP
cord-264699-l8db5gll	151	3	is	be	VBZ
cord-264699-l8db5gll	151	4	a	a	DT
cord-264699-l8db5gll	151	5	potent	potent	JJ
cord-264699-l8db5gll	151	6	stimulator	stimulator	NN
cord-264699-l8db5gll	151	7	of	of	IN
cord-264699-l8db5gll	151	8	vascular	vascular	JJ
cord-264699-l8db5gll	151	9	constriction	constriction	NN
cord-264699-l8db5gll	151	10	,	,	,
cord-264699-l8db5gll	151	11	Na	Na	NNP
cord-264699-l8db5gll	151	12	+	+	CC
cord-264699-l8db5gll	151	13	uptake	uptake	NN
cord-264699-l8db5gll	151	14	in	in	IN
cord-264699-l8db5gll	151	15	the	the	DT
cord-264699-l8db5gll	151	16	renal	renal	JJ
cord-264699-l8db5gll	151	17	tubules	tubule	NNS
cord-264699-l8db5gll	151	18	,	,	,
cord-264699-l8db5gll	151	19	aldosterone	aldosterone	NN
cord-264699-l8db5gll	151	20	secretion	secretion	NN
cord-264699-l8db5gll	151	21	from	from	IN
cord-264699-l8db5gll	151	22	the	the	DT
cord-264699-l8db5gll	151	23	adrenal	adrenal	JJ
cord-264699-l8db5gll	151	24	glands	gland	NNS
cord-264699-l8db5gll	151	25	and	and	CC
cord-264699-l8db5gll	151	26	vasopressin	vasopressin	NN
cord-264699-l8db5gll	151	27	secretion	secretion	NN
cord-264699-l8db5gll	151	28	from	from	IN
cord-264699-l8db5gll	151	29	the	the	DT
cord-264699-l8db5gll	151	30	pituitary	pituitary	JJ
cord-264699-l8db5gll	151	31	gland	gland	NN
cord-264699-l8db5gll	151	32	[	[	-LRB-
cord-264699-l8db5gll	151	33	53	53	CD
cord-264699-l8db5gll	151	34	]	]	-RRB-
cord-264699-l8db5gll	151	35	.	.	.
cord-264699-l8db5gll	152	1	ANG	ANG	NNP
cord-264699-l8db5gll	152	2	II	II	NNP
cord-264699-l8db5gll	152	3	also	also	RB
cord-264699-l8db5gll	152	4	has	have	VBZ
cord-264699-l8db5gll	152	5	important	important	JJ
cord-264699-l8db5gll	152	6	roles	role	NNS
cord-264699-l8db5gll	152	7	in	in	IN
cord-264699-l8db5gll	152	8	lung	lung	NN
cord-264699-l8db5gll	152	9	physiology	physiology	NN
cord-264699-l8db5gll	152	10	and	and	CC
cord-264699-l8db5gll	152	11	pathophysiology	pathophysiology	NN
cord-264699-l8db5gll	152	12	[	[	-LRB-
cord-264699-l8db5gll	152	13	51	51	CD
cord-264699-l8db5gll	152	14	]	]	-RRB-
cord-264699-l8db5gll	152	15	.	.	.
cord-264699-l8db5gll	153	1	Indeed	indeed	RB
cord-264699-l8db5gll	153	2	,	,	,
cord-264699-l8db5gll	153	3	ACE	ACE	NNP
cord-264699-l8db5gll	153	4	and	and	CC
cord-264699-l8db5gll	153	5	ANG	ANG	NNP
cord-264699-l8db5gll	153	6	II	II	NNP
cord-264699-l8db5gll	153	7	function	function	NN
cord-264699-l8db5gll	153	8	as	as	IN
cord-264699-l8db5gll	153	9	promoting	promote	VBG
cord-264699-l8db5gll	153	10	factors	factor	NNS
cord-264699-l8db5gll	153	11	for	for	IN
cord-264699-l8db5gll	153	12	acute	acute	JJ
cord-264699-l8db5gll	153	13	lung	lung	NN
cord-264699-l8db5gll	153	14	injury	injury	NN
cord-264699-l8db5gll	153	15	,	,	,
cord-264699-l8db5gll	153	16	whereas	whereas	IN
cord-264699-l8db5gll	153	17	ACE2	ACE2	NNP
cord-264699-l8db5gll	153	18	protects	protect	VBZ
cord-264699-l8db5gll	153	19	against	against	IN
cord-264699-l8db5gll	153	20	lung	lung	NN
cord-264699-l8db5gll	153	21	injury	injury	NN
cord-264699-l8db5gll	153	22	[	[	-LRB-
cord-264699-l8db5gll	153	23	51	51	CD
cord-264699-l8db5gll	153	24	]	]	-RRB-
cord-264699-l8db5gll	153	25	.	.	.
cord-264699-l8db5gll	154	1	As	as	IN
cord-264699-l8db5gll	154	2	SARS	SARS	NNP
cord-264699-l8db5gll	154	3	-	-	HYPH
cord-264699-l8db5gll	154	4	CoV	CoV	NNP
cord-264699-l8db5gll	154	5	infection	infection	NN
cord-264699-l8db5gll	154	6	downregulates	downregulate	VBZ
cord-264699-l8db5gll	154	7	ACE2	ACE2	NNP
cord-264699-l8db5gll	154	8	expression	expression	NN
cord-264699-l8db5gll	154	9	markedly	markedly	RB
cord-264699-l8db5gll	154	10	in	in	IN
cord-264699-l8db5gll	154	11	the	the	DT
cord-264699-l8db5gll	154	12	lung	lung	NN
cord-264699-l8db5gll	154	13	and	and	CC
cord-264699-l8db5gll	154	14	reduces	reduce	VBZ
cord-264699-l8db5gll	154	15	circulating	circulate	VBG
cord-264699-l8db5gll	154	16	concentrations	concentration	NNS
cord-264699-l8db5gll	154	17	of	of	IN
cord-264699-l8db5gll	154	18	ANG	ANG	NNP
cord-264699-l8db5gll	154	19	II	II	NNP
cord-264699-l8db5gll	154	20	[	[	-LRB-
cord-264699-l8db5gll	154	21	54	54	CD
cord-264699-l8db5gll	154	22	]	]	-RRB-
cord-264699-l8db5gll	154	23	,	,	,
cord-264699-l8db5gll	154	24	it	-PRON-	PRP
cord-264699-l8db5gll	154	25	is	be	VBZ
cord-264699-l8db5gll	154	26	likely	likely	JJ
cord-264699-l8db5gll	154	27	that	that	IN
cord-264699-l8db5gll	154	28	SARS	SARS	NNP
cord-264699-l8db5gll	154	29	-	-	HYPH
cord-264699-l8db5gll	154	30	CoV	CoV	NNP
cord-264699-l8db5gll	154	31	contributes	contribute	VBZ
cord-264699-l8db5gll	154	32	to	to	IN
cord-264699-l8db5gll	154	33	severe	severe	JJ
cord-264699-l8db5gll	154	34	lung	lung	NN
cord-264699-l8db5gll	154	35	disease	disease	NN
cord-264699-l8db5gll	154	36	and	and	CC
cord-264699-l8db5gll	154	37	other	other	JJ
cord-264699-l8db5gll	154	38	systemic	systemic	JJ
cord-264699-l8db5gll	154	39	complications	complication	NNS
cord-264699-l8db5gll	154	40	through	through	IN
cord-264699-l8db5gll	154	41	dysregulation	dysregulation	NN
cord-264699-l8db5gll	154	42	of	of	IN
cord-264699-l8db5gll	154	43	the	the	DT
cord-264699-l8db5gll	154	44	reninÀangiotensin	reninàangiotensin	NN
cord-264699-l8db5gll	154	45	system	system	NN
cord-264699-l8db5gll	154	46	.	.	.
cord-264699-l8db5gll	155	1	This	this	DT
cord-264699-l8db5gll	155	2	is	be	VBZ
cord-264699-l8db5gll	155	3	in	in	IN
cord-264699-l8db5gll	155	4	contrast	contrast	NN
cord-264699-l8db5gll	155	5	to	to	IN
cord-264699-l8db5gll	155	6	other	other	JJ
cord-264699-l8db5gll	155	7	coronaviruses	coronaviruse	NNS
cord-264699-l8db5gll	155	8	that	that	WDT
cord-264699-l8db5gll	155	9	infect	infect	VBP
cord-264699-l8db5gll	155	10	the	the	DT
cord-264699-l8db5gll	155	11	lung	lung	NN
cord-264699-l8db5gll	155	12	epithelium	epithelium	NN
cord-264699-l8db5gll	155	13	like	like	IN
cord-264699-l8db5gll	155	14	SARS	SARS	NNP
cord-264699-l8db5gll	155	15	-	-	HYPH
cord-264699-l8db5gll	155	16	CoV	CoV	NNP
cord-264699-l8db5gll	155	17	but	but	CC
cord-264699-l8db5gll	155	18	cause	cause	VBP
cord-264699-l8db5gll	155	19	much	much	RB
cord-264699-l8db5gll	155	20	milder	mild	JJR
cord-264699-l8db5gll	155	21	diseases	disease	NNS
cord-264699-l8db5gll	155	22	[	[	-LRB-
cord-264699-l8db5gll	155	23	51	51	CD
cord-264699-l8db5gll	155	24	]	]	-RRB-
cord-264699-l8db5gll	155	25	.	.	.
cord-264699-l8db5gll	156	1	Conclusions	conclusion	NNS
cord-264699-l8db5gll	156	2	:	:	:
cord-264699-l8db5gll	157	1	virus	virus	NN
cord-264699-l8db5gll	157	2	-	-	HYPH
cord-264699-l8db5gll	157	3	induced	induce	VBN
cord-264699-l8db5gll	157	4	modulation	modulation	NN
cord-264699-l8db5gll	157	5	of	of	IN
cord-264699-l8db5gll	157	6	host	host	NN
cord-264699-l8db5gll	157	7	signaling	signal	VBG
cord-264699-l8db5gll	157	8	systems	system	NNS
cord-264699-l8db5gll	157	9	as	as	IN
cord-264699-l8db5gll	157	10	a	a	DT
cord-264699-l8db5gll	157	11	new	new	JJ
cord-264699-l8db5gll	157	12	therapeutic	therapeutic	JJ
cord-264699-l8db5gll	157	13	target	target	NN
cord-264699-l8db5gll	157	14	Vaccines	vaccine	NNS
cord-264699-l8db5gll	157	15	,	,	,
cord-264699-l8db5gll	157	16	which	which	WDT
cord-264699-l8db5gll	157	17	stimulate	stimulate	VBP
cord-264699-l8db5gll	157	18	the	the	DT
cord-264699-l8db5gll	157	19	host	host	NN
cord-264699-l8db5gll	157	20	-	-	HYPH
cord-264699-l8db5gll	157	21	immune	immune	JJ
cord-264699-l8db5gll	157	22	reaction	reaction	NN
cord-264699-l8db5gll	157	23	to	to	TO
cord-264699-l8db5gll	157	24	protect	protect	VB
cord-264699-l8db5gll	157	25	the	the	DT
cord-264699-l8db5gll	157	26	organism	organism	NN
cord-264699-l8db5gll	157	27	from	from	IN
cord-264699-l8db5gll	157	28	the	the	DT
cord-264699-l8db5gll	157	29	entry	entry	NN
cord-264699-l8db5gll	157	30	of	of	IN
cord-264699-l8db5gll	157	31	viruses	virus	NNS
cord-264699-l8db5gll	157	32	,	,	,
cord-264699-l8db5gll	157	33	are	be	VBP
cord-264699-l8db5gll	157	34	the	the	DT
cord-264699-l8db5gll	157	35	most	most	RBS
cord-264699-l8db5gll	157	36	effective	effective	JJ
cord-264699-l8db5gll	157	37	,	,	,
cord-264699-l8db5gll	157	38	first	first	JJ
cord-264699-l8db5gll	157	39	-	-	HYPH
cord-264699-l8db5gll	157	40	line	line	NN
cord-264699-l8db5gll	157	41	therapeutics	therapeutic	NNS
cord-264699-l8db5gll	157	42	against	against	IN
cord-264699-l8db5gll	157	43	viral	viral	JJ
cord-264699-l8db5gll	157	44	infection	infection	NN
cord-264699-l8db5gll	157	45	.	.	.
cord-264699-l8db5gll	158	1	This	this	DT
cord-264699-l8db5gll	158	2	approach	approach	NN
cord-264699-l8db5gll	158	3	has	have	VBZ
cord-264699-l8db5gll	158	4	been	be	VBN
cord-264699-l8db5gll	158	5	extremely	extremely	RB
cord-264699-l8db5gll	158	6	useful	useful	JJ
cord-264699-l8db5gll	158	7	in	in	IN
cord-264699-l8db5gll	158	8	controlling	control	VBG
cord-264699-l8db5gll	158	9	epidemics	epidemic	NNS
cord-264699-l8db5gll	158	10	,	,	,
cord-264699-l8db5gll	158	11	such	such	JJ
cord-264699-l8db5gll	158	12	as	as	IN
cord-264699-l8db5gll	158	13	those	those	DT
cord-264699-l8db5gll	158	14	caused	cause	VBN
cord-264699-l8db5gll	158	15	by	by	IN
cord-264699-l8db5gll	158	16	smallpox	smallpox	NN
cord-264699-l8db5gll	158	17	,	,	,
cord-264699-l8db5gll	158	18	poliomyelitis	poliomyelitis	NN
cord-264699-l8db5gll	158	19	,	,	,
cord-264699-l8db5gll	158	20	measles	measle	NNS
cord-264699-l8db5gll	158	21	,	,	,
cord-264699-l8db5gll	158	22	influenza	influenza	NN
cord-264699-l8db5gll	158	23	,	,	,
cord-264699-l8db5gll	158	24	varicella	varicella	NN
cord-264699-l8db5gll	158	25	and	and	CC
cord-264699-l8db5gll	158	26	rubella	rubella	NN
cord-264699-l8db5gll	158	27	viruses	virus	NNS
cord-264699-l8db5gll	158	28	[	[	-LRB-
cord-264699-l8db5gll	158	29	1	1	CD
cord-264699-l8db5gll	158	30	]	]	-RRB-
cord-264699-l8db5gll	158	31	.	.	.
cord-264699-l8db5gll	159	1	However	however	RB
cord-264699-l8db5gll	159	2	,	,	,
cord-264699-l8db5gll	159	3	some	some	DT
cord-264699-l8db5gll	159	4	viruses	virus	NNS
cord-264699-l8db5gll	159	5	are	be	VBP
cord-264699-l8db5gll	159	6	resistant	resistant	JJ
cord-264699-l8db5gll	159	7	to	to	IN
cord-264699-l8db5gll	159	8	vaccine	vaccine	NN
cord-264699-l8db5gll	159	9	development	development	NN
cord-264699-l8db5gll	159	10	by	by	IN
cord-264699-l8db5gll	159	11	conventional	conventional	JJ
cord-264699-l8db5gll	159	12	approaches	approach	NNS
cord-264699-l8db5gll	159	13	.	.	.
cord-264699-l8db5gll	160	1	For	for	IN
cord-264699-l8db5gll	160	2	example	example	NN
cord-264699-l8db5gll	160	3	,	,	,
cord-264699-l8db5gll	160	4	so	so	RB
cord-264699-l8db5gll	160	5	far	far	RB
cord-264699-l8db5gll	160	6	,	,	,
cord-264699-l8db5gll	160	7	anti	anti	JJ
cord-264699-l8db5gll	160	8	-	-	JJ
cord-264699-l8db5gll	160	9	HIV-1	hiv-1	JJ
cord-264699-l8db5gll	160	10	vaccines	vaccine	NNS
cord-264699-l8db5gll	160	11	have	have	VBP
cord-264699-l8db5gll	160	12	not	not	RB
cord-264699-l8db5gll	160	13	been	be	VBN
cord-264699-l8db5gll	160	14	sufficiently	sufficiently	RB
cord-264699-l8db5gll	160	15	effective	effective	JJ
cord-264699-l8db5gll	160	16	to	to	TO
cord-264699-l8db5gll	160	17	protect	protect	VB
cord-264699-l8db5gll	160	18	from	from	IN
cord-264699-l8db5gll	160	19	infection	infection	NN
cord-264699-l8db5gll	160	20	by	by	IN
cord-264699-l8db5gll	160	21	this	this	DT
cord-264699-l8db5gll	160	22	virus	virus	NN
cord-264699-l8db5gll	160	23	,	,	,
cord-264699-l8db5gll	160	24	despite	despite	IN
cord-264699-l8db5gll	160	25	the	the	DT
cord-264699-l8db5gll	160	26	tremendous	tremendous	JJ
cord-264699-l8db5gll	160	27	efforts	effort	NNS
cord-264699-l8db5gll	160	28	of	of	IN
cord-264699-l8db5gll	160	29	the	the	DT
cord-264699-l8db5gll	160	30	scientific	scientific	JJ
cord-264699-l8db5gll	160	31	community	community	NN
cord-264699-l8db5gll	160	32	.	.	.
cord-264699-l8db5gll	161	1	This	this	DT
cord-264699-l8db5gll	161	2	is	be	VBZ
cord-264699-l8db5gll	161	3	possibly	possibly	RB
cord-264699-l8db5gll	161	4	because	because	IN
cord-264699-l8db5gll	161	5	of	of	IN
cord-264699-l8db5gll	161	6	the	the	DT
cord-264699-l8db5gll	161	7	high	high	JJ
cord-264699-l8db5gll	161	8	genetic	genetic	JJ
cord-264699-l8db5gll	161	9	instability	instability	NN
cord-264699-l8db5gll	161	10	of	of	IN
cord-264699-l8db5gll	161	11	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	161	12	,	,	,
cord-264699-l8db5gll	161	13	which	which	WDT
cord-264699-l8db5gll	161	14	changes	change	VBZ
cord-264699-l8db5gll	161	15	the	the	DT
cord-264699-l8db5gll	161	16	immunogenicity	immunogenicity	NN
cord-264699-l8db5gll	161	17	[	[	-LRB-
cord-264699-l8db5gll	161	18	55	55	CD
cord-264699-l8db5gll	161	19	,	,	,
cord-264699-l8db5gll	161	20	56	56	CD
cord-264699-l8db5gll	161	21	]	]	-RRB-
cord-264699-l8db5gll	161	22	.	.	.
cord-264699-l8db5gll	162	1	Anti	anti	JJ
cord-264699-l8db5gll	162	2	-	-	JJ
cord-264699-l8db5gll	162	3	viral	viral	JJ
cord-264699-l8db5gll	162	4	agents	agent	NNS
cord-264699-l8db5gll	162	5	are	be	VBP
cord-264699-l8db5gll	162	6	used	use	VBN
cord-264699-l8db5gll	162	7	because	because	IN
cord-264699-l8db5gll	162	8	vaccines	vaccine	NNS
cord-264699-l8db5gll	162	9	are	be	VBP
cord-264699-l8db5gll	162	10	either	either	CC
cord-264699-l8db5gll	162	11	not	not	RB
cord-264699-l8db5gll	162	12	available	available	JJ
cord-264699-l8db5gll	162	13	or	or	CC
cord-264699-l8db5gll	162	14	have	have	VBP
cord-264699-l8db5gll	162	15	failed	fail	VBN
cord-264699-l8db5gll	162	16	to	to	TO
cord-264699-l8db5gll	162	17	protect	protect	VB
cord-264699-l8db5gll	162	18	us	-PRON-	PRP
cord-264699-l8db5gll	162	19	.	.	.
cord-264699-l8db5gll	163	1	Expansion	expansion	NN
cord-264699-l8db5gll	163	2	of	of	IN
cord-264699-l8db5gll	163	3	our	-PRON-	PRP$
cord-264699-l8db5gll	163	4	understanding	understanding	NN
cord-264699-l8db5gll	163	5	of	of	IN
cord-264699-l8db5gll	163	6	virus	virus	NN
cord-264699-l8db5gll	163	7	-	-	HYPH
cord-264699-l8db5gll	163	8	induced	induce	VBN
cord-264699-l8db5gll	163	9	modifications	modification	NNS
cord-264699-l8db5gll	163	10	of	of	IN
cord-264699-l8db5gll	163	11	the	the	DT
cord-264699-l8db5gll	163	12	host	host	NN
cord-264699-l8db5gll	163	13	signaling	signal	VBG
cord-264699-l8db5gll	163	14	systems	system	NNS
cord-264699-l8db5gll	163	15	,	,	,
cord-264699-l8db5gll	163	16	such	such	JJ
cord-264699-l8db5gll	163	17	as	as	IN
cord-264699-l8db5gll	163	18	those	those	DT
cord-264699-l8db5gll	163	19	discussed	discuss	VBN
cord-264699-l8db5gll	163	20	above	above	RB
cord-264699-l8db5gll	163	21	,	,	,
cord-264699-l8db5gll	163	22	might	may	MD
cord-264699-l8db5gll	163	23	prove	prove	VB
cord-264699-l8db5gll	163	24	highly	highly	RB
cord-264699-l8db5gll	163	25	beneficial	beneficial	JJ
cord-264699-l8db5gll	163	26	for	for	IN
cord-264699-l8db5gll	163	27	the	the	DT
cord-264699-l8db5gll	163	28	development	development	NN
cord-264699-l8db5gll	163	29	of	of	IN
cord-264699-l8db5gll	163	30	new	new	JJ
cord-264699-l8db5gll	163	31	vaccines	vaccine	NNS
cord-264699-l8db5gll	163	32	and	and	CC
cord-264699-l8db5gll	163	33	novel	novel	JJ
cord-264699-l8db5gll	163	34	anti	anti	JJ
cord-264699-l8db5gll	163	35	-	-	JJ
cord-264699-l8db5gll	163	36	viral	viral	JJ
cord-264699-l8db5gll	163	37	agents	agent	NNS
cord-264699-l8db5gll	163	38	,	,	,
cord-264699-l8db5gll	163	39	based	base	VBN
cord-264699-l8db5gll	163	40	on	on	IN
cord-264699-l8db5gll	163	41	knowledge	knowledge	NN
cord-264699-l8db5gll	163	42	of	of	IN
cord-264699-l8db5gll	163	43	the	the	DT
cord-264699-l8db5gll	163	44	potential	potential	JJ
cord-264699-l8db5gll	163	45	indispensability	indispensability	NN
cord-264699-l8db5gll	163	46	of	of	IN
cord-264699-l8db5gll	163	47	specific	specific	JJ
cord-264699-l8db5gll	163	48	viral	viral	JJ
cord-264699-l8db5gll	163	49	molecules	molecule	NNS
cord-264699-l8db5gll	163	50	for	for	IN
cord-264699-l8db5gll	163	51	the	the	DT
cord-264699-l8db5gll	163	52	entry	entry	NN
cord-264699-l8db5gll	163	53	,	,	,
cord-264699-l8db5gll	163	54	replication	replication	NN
cord-264699-l8db5gll	163	55	,	,	,
cord-264699-l8db5gll	163	56	and	and	CC
cord-264699-l8db5gll	163	57	intracellular	intracellular	JJ
cord-264699-l8db5gll	163	58	and	and	CC
cord-264699-l8db5gll	163	59	extracellular	extracellular	JJ
cord-264699-l8db5gll	163	60	survival	survival	NN
cord-264699-l8db5gll	163	61	and	and	CC
cord-264699-l8db5gll	163	62	propagation	propagation	NN
cord-264699-l8db5gll	163	63	of	of	IN
cord-264699-l8db5gll	163	64	these	these	DT
cord-264699-l8db5gll	163	65	viruses	virus	NNS
cord-264699-l8db5gll	163	66	.	.	.
cord-264699-l8db5gll	164	1	Indeed	indeed	RB
cord-264699-l8db5gll	164	2	,	,	,
cord-264699-l8db5gll	164	3	this	this	DT
cord-264699-l8db5gll	164	4	approach	approach	NN
cord-264699-l8db5gll	164	5	has	have	VBZ
cord-264699-l8db5gll	164	6	been	be	VBN
cord-264699-l8db5gll	164	7	followed	follow	VBN
cord-264699-l8db5gll	164	8	successfully	successfully	RB
cord-264699-l8db5gll	164	9	in	in	IN
cord-264699-l8db5gll	164	10	the	the	DT
cord-264699-l8db5gll	164	11	development	development	NN
cord-264699-l8db5gll	164	12	of	of	IN
cord-264699-l8db5gll	164	13	nucleoside	nucleoside	JJ
cord-264699-l8db5gll	164	14	analogs	analog	NNS
cord-264699-l8db5gll	164	15	,	,	,
cord-264699-l8db5gll	164	16	such	such	JJ
cord-264699-l8db5gll	164	17	as	as	IN
cord-264699-l8db5gll	164	18	acyclovir	acyclovir	NNP
cord-264699-l8db5gll	164	19	for	for	IN
cord-264699-l8db5gll	164	20	the	the	DT
cord-264699-l8db5gll	164	21	herpes	herpes	NNP
cord-264699-l8db5gll	164	22	simplex	simplex	NNP
cord-264699-l8db5gll	164	23	virus	virus	NN
cord-264699-l8db5gll	164	24	and	and	CC
cord-264699-l8db5gll	164	25	ganciclovir	ganciclovir	NNS
cord-264699-l8db5gll	164	26	for	for	IN
cord-264699-l8db5gll	164	27	Cytomegalovirus	Cytomegalovirus	NNP
cord-264699-l8db5gll	164	28	,	,	,
cord-264699-l8db5gll	164	29	which	which	WDT
cord-264699-l8db5gll	164	30	specifically	specifically	RB
cord-264699-l8db5gll	164	31	block	block	VBP
cord-264699-l8db5gll	164	32	transcription	transcription	NN
cord-264699-l8db5gll	164	33	promoted	promote	VBN
cord-264699-l8db5gll	164	34	by	by	IN
cord-264699-l8db5gll	164	35	virus	virus	NN
cord-264699-l8db5gll	164	36	-	-	HYPH
cord-264699-l8db5gll	164	37	encoded	encode	VBN
cord-264699-l8db5gll	164	38	and	and	CC
cord-264699-l8db5gll	164	39	virus	virus	NN
cord-264699-l8db5gll	164	40	-	-	HYPH
cord-264699-l8db5gll	164	41	specific	specific	JJ
cord-264699-l8db5gll	164	42	DNA	dna	NN
cord-264699-l8db5gll	164	43	polymerases	polymerase	NNS
cord-264699-l8db5gll	164	44	[	[	-LRB-
cord-264699-l8db5gll	164	45	57	57	CD
cord-264699-l8db5gll	164	46	]	]	-RRB-
cord-264699-l8db5gll	164	47	.	.	.
cord-264699-l8db5gll	165	1	Oseltamivir	Oseltamivir	NNP
cord-264699-l8db5gll	165	2	,	,	,
cord-264699-l8db5gll	165	3	a	a	DT
cord-264699-l8db5gll	165	4	neuraminidase	neuraminidase	NN
cord-264699-l8db5gll	165	5	inhibitor	inhibitor	NN
cord-264699-l8db5gll	165	6	that	that	WDT
cord-264699-l8db5gll	165	7	blocks	block	VBZ
cord-264699-l8db5gll	165	8	the	the	DT
cord-264699-l8db5gll	165	9	influenza	influenza	NN
cord-264699-l8db5gll	165	10	virusencoded	virusencode	VBN
cord-264699-l8db5gll	165	11	neuraminidase	neuraminidase	NN
cord-264699-l8db5gll	165	12	,	,	,
cord-264699-l8db5gll	165	13	is	be	VBZ
cord-264699-l8db5gll	165	14	effective	effective	JJ
cord-264699-l8db5gll	165	15	in	in	IN
cord-264699-l8db5gll	165	16	controlling	control	VBG
cord-264699-l8db5gll	165	17	infection	infection	NN
cord-264699-l8db5gll	165	18	by	by	IN
cord-264699-l8db5gll	165	19	blocking	block	VBG
cord-264699-l8db5gll	165	20	the	the	DT
cord-264699-l8db5gll	165	21	release	release	NN
cord-264699-l8db5gll	165	22	of	of	IN
cord-264699-l8db5gll	165	23	newly	newly	RB
cord-264699-l8db5gll	165	24	replicated	replicate	VBN
cord-264699-l8db5gll	165	25	viruses	virus	NNS
cord-264699-l8db5gll	165	26	from	from	IN
cord-264699-l8db5gll	165	27	the	the	DT
cord-264699-l8db5gll	165	28	infected	infected	JJ
cord-264699-l8db5gll	165	29	cells	cell	NNS
cord-264699-l8db5gll	165	30	,	,	,
cord-264699-l8db5gll	165	31	a	a	DT
cord-264699-l8db5gll	165	32	step	step	NN
cord-264699-l8db5gll	165	33	in	in	IN
cord-264699-l8db5gll	165	34	which	which	WDT
cord-264699-l8db5gll	165	35	this	this	DT
cord-264699-l8db5gll	165	36	enzyme	enzyme	NN
cord-264699-l8db5gll	165	37	has	have	VBZ
cord-264699-l8db5gll	165	38	a	a	DT
cord-264699-l8db5gll	165	39	major	major	JJ
cord-264699-l8db5gll	165	40	role	role	NN
cord-264699-l8db5gll	165	41	[	[	-LRB-
cord-264699-l8db5gll	165	42	58	58	CD
cord-264699-l8db5gll	165	43	]	]	-RRB-
cord-264699-l8db5gll	165	44	.	.	.
cord-264699-l8db5gll	166	1	Thus	thus	RB
cord-264699-l8db5gll	166	2	,	,	,
cord-264699-l8db5gll	166	3	either	either	CC
cord-264699-l8db5gll	166	4	vaccines	vaccine	NNS
cord-264699-l8db5gll	166	5	or	or	CC
cord-264699-l8db5gll	166	6	chemical	chemical	JJ
cord-264699-l8db5gll	166	7	compounds	compound	NNS
cord-264699-l8db5gll	166	8	,	,	,
cord-264699-l8db5gll	166	9	including	include	VBG
cord-264699-l8db5gll	166	10	nucleotides	nucleotide	NNS
cord-264699-l8db5gll	166	11	(	(	-LRB-
cord-264699-l8db5gll	166	12	e.g.	e.g.	RB
cord-264699-l8db5gll	166	13	antisense	antisense	NN
cord-264699-l8db5gll	166	14	DNA	DNA	NNP
cord-264699-l8db5gll	166	15	and	and	CC
cord-264699-l8db5gll	166	16	siRNA	siRNA	NNP
cord-264699-l8db5gll	166	17	)	)	-RRB-
cord-264699-l8db5gll	166	18	that	that	WDT
cord-264699-l8db5gll	166	19	inhibit	inhibit	VBP
cord-264699-l8db5gll	166	20	the	the	DT
cord-264699-l8db5gll	166	21	expression	expression	NN
cord-264699-l8db5gll	166	22	and/or	and/or	CC
cord-264699-l8db5gll	166	23	function	function	NN
cord-264699-l8db5gll	166	24	of	of	IN
cord-264699-l8db5gll	166	25	specific	specific	JJ
cord-264699-l8db5gll	166	26	viral	viral	JJ
cord-264699-l8db5gll	166	27	molecules	molecule	NNS
cord-264699-l8db5gll	166	28	,	,	,
cord-264699-l8db5gll	166	29	are	be	VBP
cord-264699-l8db5gll	166	30	promising	promising	JJ
cord-264699-l8db5gll	166	31	approaches	approach	NNS
cord-264699-l8db5gll	166	32	for	for	IN
cord-264699-l8db5gll	166	33	the	the	DT
cord-264699-l8db5gll	166	34	treatment	treatment	NN
cord-264699-l8db5gll	166	35	of	of	IN
cord-264699-l8db5gll	166	36	viral	viral	JJ
cord-264699-l8db5gll	166	37	illnesses	illness	NNS
cord-264699-l8db5gll	166	38	.	.	.
cord-264699-l8db5gll	167	1	Indeed	indeed	RB
cord-264699-l8db5gll	167	2	,	,	,
cord-264699-l8db5gll	167	3	vaccines	vaccine	NNS
cord-264699-l8db5gll	167	4	against	against	IN
cord-264699-l8db5gll	167	5	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	167	6	Tat	Tat	NNP
cord-264699-l8db5gll	167	7	are	be	VBP
cord-264699-l8db5gll	167	8	under	under	IN
cord-264699-l8db5gll	167	9	development	development	NN
cord-264699-l8db5gll	167	10	with	with	IN
cord-264699-l8db5gll	167	11	promising	promising	JJ
cord-264699-l8db5gll	167	12	effects	effect	NNS
cord-264699-l8db5gll	167	13	[	[	-LRB-
cord-264699-l8db5gll	167	14	59	59	CD
cord-264699-l8db5gll	167	15	]	]	-RRB-
cord-264699-l8db5gll	167	16	.	.	.
cord-264699-l8db5gll	168	1	We	-PRON-	PRP
cord-264699-l8db5gll	168	2	envision	envision	VBP
cord-264699-l8db5gll	168	3	that	that	IN
cord-264699-l8db5gll	168	4	future	future	JJ
cord-264699-l8db5gll	168	5	research	research	NN
cord-264699-l8db5gll	168	6	to	to	TO
cord-264699-l8db5gll	168	7	further	further	RB
cord-264699-l8db5gll	168	8	elucidate	elucidate	VB
cord-264699-l8db5gll	168	9	the	the	DT
cord-264699-l8db5gll	168	10	effects	effect	NNS
cord-264699-l8db5gll	168	11	of	of	IN
cord-264699-l8db5gll	168	12	viral	viral	JJ
cord-264699-l8db5gll	168	13	molecules	molecule	NNS
cord-264699-l8db5gll	168	14	on	on	IN
cord-264699-l8db5gll	168	15	the	the	DT
cord-264699-l8db5gll	168	16	host	host	NN
cord-264699-l8db5gll	168	17	endocrine	endocrine	NN
cord-264699-l8db5gll	168	18	signaling	signal	VBG
cord-264699-l8db5gll	168	19	systems	system	NNS
cord-264699-l8db5gll	168	20	will	will	MD
cord-264699-l8db5gll	168	21	improve	improve	VB
cord-264699-l8db5gll	168	22	our	-PRON-	PRP$
cord-264699-l8db5gll	168	23	ability	ability	NN
cord-264699-l8db5gll	168	24	to	to	TO
cord-264699-l8db5gll	168	25	intercept	intercept	VB
cord-264699-l8db5gll	168	26	viral	viral	JJ
cord-264699-l8db5gll	168	27	infection	infection	NN
cord-264699-l8db5gll	168	28	and	and	CC
cord-264699-l8db5gll	168	29	prevent	prevent	VB
cord-264699-l8db5gll	168	30	virus	virus	NN
cord-264699-l8db5gll	168	31	infection	infection	NN
cord-264699-l8db5gll	168	32	-	-	HYPH
cord-264699-l8db5gll	168	33	associated	associate	VBN
cord-264699-l8db5gll	168	34	diseases	disease	NNS
cord-264699-l8db5gll	168	35	that	that	WDT
cord-264699-l8db5gll	168	36	affect	affect	VBP
cord-264699-l8db5gll	168	37	endocrine	endocrine	JJ
cord-264699-l8db5gll	168	38	systems	system	NNS
cord-264699-l8db5gll	168	39	.	.	.
cord-264699-l8db5gll	169	1	and	and	CC
cord-264699-l8db5gll	169	2	endocrine	endocrine	JJ
cord-264699-l8db5gll	169	3	target	target	NN
cord-264699-l8db5gll	169	4	organs	organ	NNS
cord-264699-l8db5gll	169	5	.	.	.
cord-264699-l8db5gll	170	1	A	a	DT
cord-264699-l8db5gll	170	2	different	different	JJ
cord-264699-l8db5gll	170	3	view	view	NN
cord-264699-l8db5gll	170	4	of	of	IN
cord-264699-l8db5gll	170	5	smallpox	smallpox	NN
cord-264699-l8db5gll	170	6	and	and	CC
cord-264699-l8db5gll	170	7	vaccination	vaccination	NN
cord-264699-l8db5gll	170	8	HIV	HIV	NNP
cord-264699-l8db5gll	170	9	/	/	SYM
cord-264699-l8db5gll	170	10	AIDS	AIDS	NNP
cord-264699-l8db5gll	170	11	epidemiology	epidemiology	NN
cord-264699-l8db5gll	170	12	,	,	,
cord-264699-l8db5gll	170	13	pathogenesis	pathogenesis	NN
cord-264699-l8db5gll	170	14	,	,	,
cord-264699-l8db5gll	170	15	prevention	prevention	NN
cord-264699-l8db5gll	170	16	,	,	,
cord-264699-l8db5gll	170	17	and	and	CC
cord-264699-l8db5gll	170	18	treatment	treatment	NN
cord-264699-l8db5gll	170	19	ACE2	ACE2	NNP
cord-264699-l8db5gll	170	20	:	:	:
cord-264699-l8db5gll	170	21	from	from	IN
cord-264699-l8db5gll	170	22	vasopeptidase	vasopeptidase	NNP
cord-264699-l8db5gll	170	23	to	to	IN
cord-264699-l8db5gll	170	24	SARS	SARS	NNP
cord-264699-l8db5gll	170	25	virus	virus	NN
cord-264699-l8db5gll	170	26	receptor	receptor	NN
cord-264699-l8db5gll	170	27	Immunology	Immunology	NNP
cord-264699-l8db5gll	170	28	of	of	IN
cord-264699-l8db5gll	170	29	viral	viral	JJ
cord-264699-l8db5gll	170	30	infections	infection	NNS
cord-264699-l8db5gll	171	1	Molecular	molecular	JJ
cord-264699-l8db5gll	171	2	mimicry	mimicry	NN
cord-264699-l8db5gll	171	3	and	and	CC
cord-264699-l8db5gll	171	4	immune	immune	NN
cord-264699-l8db5gll	171	5	-	-	HYPH
cord-264699-l8db5gll	171	6	mediated	mediate	VBN
cord-264699-l8db5gll	171	7	diseases	disease	NNS
cord-264699-l8db5gll	172	1	The	the	DT
cord-264699-l8db5gll	172	2	hypothalamic	hypothalamic	JJ
cord-264699-l8db5gll	172	3	-	-	HYPH
cord-264699-l8db5gll	172	4	pituitary	pituitary	NN
cord-264699-l8db5gll	172	5	-	-	HYPH
cord-264699-l8db5gll	172	6	adrenal	adrenal	NN
cord-264699-l8db5gll	172	7	axis	axis	NN
cord-264699-l8db5gll	172	8	and	and	CC
cord-264699-l8db5gll	172	9	immune	immune	NN
cord-264699-l8db5gll	172	10	-	-	HYPH
cord-264699-l8db5gll	172	11	mediated	mediate	VBN
cord-264699-l8db5gll	172	12	inflammation	inflammation	NN
cord-264699-l8db5gll	172	13	Effectiveness	effectiveness	NN
cord-264699-l8db5gll	172	14	of	of	IN
cord-264699-l8db5gll	172	15	prolonged	prolong	VBN
cord-264699-l8db5gll	172	16	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	172	17	treatment	treatment	NN
cord-264699-l8db5gll	172	18	in	in	IN
cord-264699-l8db5gll	172	19	acute	acute	JJ
cord-264699-l8db5gll	172	20	respiratory	respiratory	JJ
cord-264699-l8db5gll	172	21	distress	distress	NN
cord-264699-l8db5gll	172	22	syndrome	syndrome	NN
cord-264699-l8db5gll	172	23	:	:	:
cord-264699-l8db5gll	172	24	the	the	DT
cord-264699-l8db5gll	172	25	right	right	JJ
cord-264699-l8db5gll	172	26	drug	drug	NN
cord-264699-l8db5gll	172	27	,	,	,
cord-264699-l8db5gll	172	28	the	the	DT
cord-264699-l8db5gll	172	29	right	right	JJ
cord-264699-l8db5gll	172	30	way	way	NN
cord-264699-l8db5gll	172	31	?	?	.
cord-264699-l8db5gll	173	1	Immune	immune	JJ
cord-264699-l8db5gll	173	2	modulation	modulation	NN
cord-264699-l8db5gll	173	3	of	of	IN
cord-264699-l8db5gll	173	4	the	the	DT
cord-264699-l8db5gll	173	5	hypothalamicpituitary	hypothalamicpituitary	JJ
cord-264699-l8db5gll	173	6	-	-	HYPH
cord-264699-l8db5gll	173	7	adrenal	adrenal	JJ
cord-264699-l8db5gll	173	8	(	(	-LRB-
cord-264699-l8db5gll	173	9	HPA	HPA	NNP
cord-264699-l8db5gll	173	10	)	)	-RRB-
cord-264699-l8db5gll	173	11	axis	axis	NN
cord-264699-l8db5gll	173	12	during	during	IN
cord-264699-l8db5gll	173	13	viral	viral	JJ
cord-264699-l8db5gll	173	14	infection	infection	NN
cord-264699-l8db5gll	173	15	Adenovirus	Adenovirus	NNP
cord-264699-l8db5gll	173	16	E1A	e1a	NN
cord-264699-l8db5gll	173	17	:	:	:
cord-264699-l8db5gll	173	18	remodelling	remodelle	VBG
cord-264699-l8db5gll	173	19	the	the	DT
cord-264699-l8db5gll	173	20	host	host	NN
cord-264699-l8db5gll	173	21	cell	cell	NN
cord-264699-l8db5gll	173	22	,	,	,
cord-264699-l8db5gll	173	23	a	a	DT
cord-264699-l8db5gll	173	24	life	life	NN
cord-264699-l8db5gll	173	25	or	or	CC
cord-264699-l8db5gll	173	26	death	death	NN
cord-264699-l8db5gll	173	27	experience	experience	NN
cord-264699-l8db5gll	173	28	AIDS	AIDS	NNP
cord-264699-l8db5gll	173	29	-	-	HYPH
cord-264699-l8db5gll	173	30	related	relate	VBN
cord-264699-l8db5gll	173	31	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	173	32	/	/	SYM
cord-264699-l8db5gll	173	33	insulin	insulin	NN
cord-264699-l8db5gll	173	34	resistance	resistance	NN
cord-264699-l8db5gll	173	35	syndrome	syndrome	NN
cord-264699-l8db5gll	173	36	Hypercalcemia	Hypercalcemia	NNP
cord-264699-l8db5gll	173	37	,	,	,
cord-264699-l8db5gll	173	38	parathyroid	parathyroid	JJ
cord-264699-l8db5gll	173	39	hormone	hormone	NN
cord-264699-l8db5gll	173	40	-	-	HYPH
cord-264699-l8db5gll	173	41	related	relate	VBN
cord-264699-l8db5gll	173	42	protein	protein	NN
cord-264699-l8db5gll	173	43	expression	expression	NN
cord-264699-l8db5gll	173	44	and	and	CC
cord-264699-l8db5gll	173	45	human	human	JJ
cord-264699-l8db5gll	173	46	T	t	NN
cord-264699-l8db5gll	173	47	-	-	HYPH
cord-264699-l8db5gll	173	48	cell	cell	NN
cord-264699-l8db5gll	173	49	leukemia	leukemia	NN
cord-264699-l8db5gll	173	50	virus	virus	NN
cord-264699-l8db5gll	173	51	infection	infection	NN
cord-264699-l8db5gll	174	1	HIV	HIV	NNP
cord-264699-l8db5gll	174	2	gp120	gp120	NNP
cord-264699-l8db5gll	174	3	inhibits	inhibit	VBZ
cord-264699-l8db5gll	174	4	the	the	DT
cord-264699-l8db5gll	174	5	somatotropic	somatotropic	JJ
cord-264699-l8db5gll	174	6	axis	axis	NN
cord-264699-l8db5gll	174	7	:	:	:
cord-264699-l8db5gll	174	8	a	a	DT
cord-264699-l8db5gll	174	9	possible	possible	JJ
cord-264699-l8db5gll	174	10	GH	gh	NN
cord-264699-l8db5gll	174	11	-	-	HYPH
cord-264699-l8db5gll	174	12	releasing	release	VBG
cord-264699-l8db5gll	174	13	hormone	hormone	NN
cord-264699-l8db5gll	174	14	receptor	receptor	NN
cord-264699-l8db5gll	174	15	mechanism	mechanism	NN
cord-264699-l8db5gll	174	16	for	for	IN
cord-264699-l8db5gll	174	17	the	the	DT
cord-264699-l8db5gll	174	18	pathogenesis	pathogenesis	NN
cord-264699-l8db5gll	174	19	of	of	IN
cord-264699-l8db5gll	174	20	AIDS	AIDS	NNP
cord-264699-l8db5gll	174	21	wasting	waste	VBG
cord-264699-l8db5gll	174	22	Perturbation	perturbation	NN
cord-264699-l8db5gll	174	23	of	of	IN
cord-264699-l8db5gll	174	24	in	in	FW
cord-264699-l8db5gll	174	25	vitro	vitro	FW
cord-264699-l8db5gll	174	26	HIV	HIV	NNP
cord-264699-l8db5gll	174	27	pathogenic	pathogenic	JJ
cord-264699-l8db5gll	174	28	effects	effect	NNS
cord-264699-l8db5gll	174	29	by	by	IN
cord-264699-l8db5gll	174	30	peptides	peptide	NNS
cord-264699-l8db5gll	174	31	showing	show	VBG
cord-264699-l8db5gll	174	32	sequence	sequence	NN
cord-264699-l8db5gll	174	33	similarities	similarity	NNS
cord-264699-l8db5gll	174	34	with	with	IN
cord-264699-l8db5gll	174	35	the	the	DT
cord-264699-l8db5gll	174	36	C2	C2	NNP
cord-264699-l8db5gll	174	37	conserved	conserve	VBN
cord-264699-l8db5gll	174	38	domain	domain	NN
cord-264699-l8db5gll	174	39	of	of	IN
cord-264699-l8db5gll	174	40	gp120	gp120	DT
cord-264699-l8db5gll	174	41	Vasoactive	vasoactive	JJ
cord-264699-l8db5gll	174	42	intestinal	intestinal	JJ
cord-264699-l8db5gll	174	43	peptide	peptide	NN
cord-264699-l8db5gll	175	1	1	1	LS
cord-264699-l8db5gll	175	2	-	-	SYM
cord-264699-l8db5gll	175	3	12	12	CD
cord-264699-l8db5gll	176	1	:	:	:
cord-264699-l8db5gll	176	2	a	a	DT
cord-264699-l8db5gll	176	3	ligand	ligand	NN
cord-264699-l8db5gll	176	4	for	for	IN
cord-264699-l8db5gll	176	5	the	the	DT
cord-264699-l8db5gll	176	6	CD4	CD4	NNP
cord-264699-l8db5gll	176	7	(	(	-LRB-
cord-264699-l8db5gll	176	8	T4)/human	t4)/human	JJ
cord-264699-l8db5gll	176	9	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	176	10	virus	virus	NN
cord-264699-l8db5gll	176	11	receptor	receptor	NN
cord-264699-l8db5gll	176	12	Nucleotide	nucleotide	NN
cord-264699-l8db5gll	176	13	and	and	CC
cord-264699-l8db5gll	176	14	amino	amino	NN
cord-264699-l8db5gll	176	15	acid	acid	NN
cord-264699-l8db5gll	176	16	homology	homology	NN
cord-264699-l8db5gll	176	17	between	between	IN
cord-264699-l8db5gll	176	18	the	the	DT
cord-264699-l8db5gll	176	19	human	human	JJ
cord-264699-l8db5gll	176	20	thyrotropin	thyrotropin	NN
cord-264699-l8db5gll	176	21	receptor	receptor	NN
cord-264699-l8db5gll	176	22	and	and	CC
cord-264699-l8db5gll	176	23	the	the	DT
cord-264699-l8db5gll	176	24	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	176	25	Nef	Nef	NNP
cord-264699-l8db5gll	176	26	protein	protein	NN
cord-264699-l8db5gll	176	27	:	:	:
cord-264699-l8db5gll	176	28	identification	identification	NN
cord-264699-l8db5gll	176	29	and	and	CC
cord-264699-l8db5gll	176	30	functional	functional	JJ
cord-264699-l8db5gll	176	31	analysis	analysis	NN
cord-264699-l8db5gll	177	1	Glucocorticoid	glucocorticoid	JJ
cord-264699-l8db5gll	177	2	and	and	CC
cord-264699-l8db5gll	177	3	mineralocorticoid	mineralocorticoid	NN
cord-264699-l8db5gll	177	4	resistance	resistance	NN
cord-264699-l8db5gll	177	5	/	/	SYM
cord-264699-l8db5gll	177	6	hypersensitivity	hypersensitivity	NN
cord-264699-l8db5gll	177	7	syndromes	syndrome	NNS
cord-264699-l8db5gll	178	1	Constitutive	constitutive	JJ
cord-264699-l8db5gll	178	2	expression	expression	NN
cord-264699-l8db5gll	178	3	of	of	IN
cord-264699-l8db5gll	178	4	parathyroid	parathyroid	JJ
cord-264699-l8db5gll	178	5	hormone	hormone	NN
cord-264699-l8db5gll	178	6	-	-	HYPH
cord-264699-l8db5gll	178	7	related	relate	VBN
cord-264699-l8db5gll	178	8	protein	protein	NN
cord-264699-l8db5gll	178	9	gene	gene	NN
cord-264699-l8db5gll	178	10	in	in	IN
cord-264699-l8db5gll	178	11	human	human	JJ
cord-264699-l8db5gll	178	12	T	T	NNP
cord-264699-l8db5gll	178	13	cell	cell	NN
cord-264699-l8db5gll	178	14	leukemia	leukemia	NN
cord-264699-l8db5gll	178	15	virus	virus	NN
cord-264699-l8db5gll	178	16	type	type	NN
cord-264699-l8db5gll	178	17	1	1	CD
cord-264699-l8db5gll	178	18	(	(	-LRB-
cord-264699-l8db5gll	178	19	HTLV-1	HTLV-1	NNP
cord-264699-l8db5gll	178	20	)	)	-RRB-
cord-264699-l8db5gll	178	21	carriers	carrier	NNS
cord-264699-l8db5gll	178	22	and	and	CC
cord-264699-l8db5gll	178	23	adult	adult	NN
cord-264699-l8db5gll	178	24	T	T	NNP
cord-264699-l8db5gll	178	25	cell	cell	NN
cord-264699-l8db5gll	178	26	leukemia	leukemia	NN
cord-264699-l8db5gll	178	27	patients	patient	NNS
cord-264699-l8db5gll	178	28	that	that	WDT
cord-264699-l8db5gll	178	29	can	can	MD
cord-264699-l8db5gll	178	30	be	be	VB
cord-264699-l8db5gll	178	31	transactivated	transactivate	VBN
cord-264699-l8db5gll	178	32	by	by	IN
cord-264699-l8db5gll	178	33	HTLV-1	HTLV-1	NNP
cord-264699-l8db5gll	178	34	tax	tax	NN
cord-264699-l8db5gll	178	35	gene	gene	NN
cord-264699-l8db5gll	178	36	Parathyroid	Parathyroid	NNP
cord-264699-l8db5gll	178	37	hormone	hormone	NN
cord-264699-l8db5gll	178	38	and	and	CC
cord-264699-l8db5gll	178	39	parathyroid	parathyroid	JJ
cord-264699-l8db5gll	178	40	hormone	hormone	NN
cord-264699-l8db5gll	178	41	-	-	HYPH
cord-264699-l8db5gll	178	42	related	relate	VBN
cord-264699-l8db5gll	178	43	peptide	peptide	NN
cord-264699-l8db5gll	178	44	,	,	,
cord-264699-l8db5gll	178	45	and	and	CC
cord-264699-l8db5gll	178	46	their	-PRON-	PRP$
cord-264699-l8db5gll	178	47	receptors	receptor	NNS
cord-264699-l8db5gll	178	48	Molecular	molecular	JJ
cord-264699-l8db5gll	178	49	mechanisms	mechanism	NNS
cord-264699-l8db5gll	178	50	of	of	IN
cord-264699-l8db5gll	178	51	cellular	cellular	JJ
cord-264699-l8db5gll	178	52	transformation	transformation	NN
cord-264699-l8db5gll	178	53	by	by	IN
cord-264699-l8db5gll	178	54	HTLV-1	HTLV-1	NNP
cord-264699-l8db5gll	178	55	Tax	Tax	NNP
cord-264699-l8db5gll	178	56	Interaction	Interaction	NNP
cord-264699-l8db5gll	178	57	of	of	IN
cord-264699-l8db5gll	178	58	human	human	JJ
cord-264699-l8db5gll	178	59	T	t	NN
cord-264699-l8db5gll	178	60	-	-	HYPH
cord-264699-l8db5gll	178	61	cell	cell	NN
cord-264699-l8db5gll	178	62	lymphotropic	lymphotropic	NNP
cord-264699-l8db5gll	178	63	virus	virus	NN
cord-264699-l8db5gll	178	64	type	type	NN
cord-264699-l8db5gll	178	65	I	I	NNP
cord-264699-l8db5gll	178	66	Tax	Tax	NNP
cord-264699-l8db5gll	178	67	,	,	,
cord-264699-l8db5gll	178	68	Ets1	Ets1	NNP
cord-264699-l8db5gll	178	69	,	,	,
cord-264699-l8db5gll	178	70	and	and	CC
cord-264699-l8db5gll	178	71	Sp1	sp1	NN
cord-264699-l8db5gll	178	72	in	in	IN
cord-264699-l8db5gll	178	73	transactivation	transactivation	NN
cord-264699-l8db5gll	178	74	of	of	IN
cord-264699-l8db5gll	178	75	the	the	DT
cord-264699-l8db5gll	178	76	PTHrP	PTHrP	NNP
cord-264699-l8db5gll	178	77	P2	P2	NNP
cord-264699-l8db5gll	178	78	promoter	promoter	NN
cord-264699-l8db5gll	178	79	Humoral	Humoral	NNP
cord-264699-l8db5gll	178	80	hypercalcemia	hypercalcemia	NN
cord-264699-l8db5gll	178	81	of	of	IN
cord-264699-l8db5gll	178	82	malignancy	malignancy	NN
cord-264699-l8db5gll	178	83	:	:	:
cord-264699-l8db5gll	178	84	severe	severe	JJ
cord-264699-l8db5gll	178	85	combined	combine	VBN
cord-264699-l8db5gll	178	86	immunodeficient	immunodeficient	JJ
cord-264699-l8db5gll	178	87	/	/	SYM
cord-264699-l8db5gll	178	88	beige	beige	JJ
cord-264699-l8db5gll	178	89	mouse	mouse	NN
cord-264699-l8db5gll	178	90	model	model	NN
cord-264699-l8db5gll	178	91	of	of	IN
cord-264699-l8db5gll	179	1	adult	adult	NN
cord-264699-l8db5gll	179	2	T	T	NNP
cord-264699-l8db5gll	179	3	-	-	HYPH
cord-264699-l8db5gll	179	4	cell	cell	NN
cord-264699-l8db5gll	179	5	ACE	ace	NN
cord-264699-l8db5gll	179	6	converts	convert	VBZ
cord-264699-l8db5gll	180	1	angiotensin	angiotensin	NNP
cord-264699-l8db5gll	181	1	I	-PRON-	PRP
cord-264699-l8db5gll	181	2	(	(	-LRB-
cord-264699-l8db5gll	181	3	ANG	ANG	NNP
cord-264699-l8db5gll	181	4	I	I	NNP
cord-264699-l8db5gll	181	5	)	)	-RRB-
cord-264699-l8db5gll	181	6	into	into	IN
cord-264699-l8db5gll	181	7	ANG	ANG	NNP
cord-264699-l8db5gll	181	8	II	II	NNP
cord-264699-l8db5gll	181	9	,	,	,
cord-264699-l8db5gll	181	10	which	which	WDT
cord-264699-l8db5gll	181	11	acts	act	VBZ
cord-264699-l8db5gll	181	12	as	as	IN
cord-264699-l8db5gll	181	13	a	a	DT
cord-264699-l8db5gll	181	14	vasopressor	vasopressor	NN
cord-264699-l8db5gll	181	15	and	and	CC
cord-264699-l8db5gll	181	16	a	a	DT
cord-264699-l8db5gll	181	17	mitogen	mitogen	NN
cord-264699-l8db5gll	181	18	for	for	IN
cord-264699-l8db5gll	181	19	smooth	smooth	JJ
cord-264699-l8db5gll	181	20	muscle	muscle	NN
cord-264699-l8db5gll	181	21	cells	cell	NNS
cord-264699-l8db5gll	181	22	and	and	CC
cord-264699-l8db5gll	181	23	fibroblasts	fibroblast	NNS
cord-264699-l8db5gll	181	24	through	through	IN
cord-264699-l8db5gll	181	25	the	the	DT
cord-264699-l8db5gll	181	26	angiotensin	angiotensin	NN
cord-264699-l8db5gll	181	27	1	1	CD
cord-264699-l8db5gll	181	28	(	(	-LRB-
cord-264699-l8db5gll	181	29	AT1	at1	NN
cord-264699-l8db5gll	181	30	)	)	-RRB-
cord-264699-l8db5gll	181	31	receptor	receptor	NN
cord-264699-l8db5gll	181	32	.	.	.
cord-264699-l8db5gll	182	1	By	by	IN
cord-264699-l8db5gll	182	2	contrast	contrast	NN
cord-264699-l8db5gll	182	3	,	,	,
cord-264699-l8db5gll	182	4	ACE2	ACE2	NNP
cord-264699-l8db5gll	182	5	[	[	-LRB-
cord-264699-l8db5gll	182	6	53	53	CD
cord-264699-l8db5gll	182	7	]	]	-RRB-
cord-264699-l8db5gll	182	8	converts	convert	VBZ
cord-264699-l8db5gll	182	9	ANG	ANG	NNP
cord-264699-l8db5gll	182	10	I	I	NNP
cord-264699-l8db5gll	182	11	and	and	CC
cord-264699-l8db5gll	182	12	ANG	ANG	NNP
cord-264699-l8db5gll	182	13	II	II	NNP
cord-264699-l8db5gll	182	14	into	into	IN
cord-264699-l8db5gll	182	15	angiotensin	angiotensin	NN
cord-264699-l8db5gll	182	16	(	(	-LRB-
cord-264699-l8db5gll	182	17	1	1	CD
cord-264699-l8db5gll	182	18	-	-	SYM
cord-264699-l8db5gll	182	19	9	9	CD
cord-264699-l8db5gll	182	20	)	)	-RRB-
cord-264699-l8db5gll	182	21	and	and	CC
cord-264699-l8db5gll	182	22	angiotensin	angiotensin	NN
cord-264699-l8db5gll	182	23	(	(	-LRB-
cord-264699-l8db5gll	182	24	1	1	CD
cord-264699-l8db5gll	182	25	-	-	SYM
cord-264699-l8db5gll	182	26	7	7	CD
cord-264699-l8db5gll	182	27	)	)	-RRB-
cord-264699-l8db5gll	182	28	,	,	,
cord-264699-l8db5gll	182	29	respectively	respectively	RB
cord-264699-l8db5gll	182	30	lymphoma	lymphoma	NN
cord-264699-l8db5gll	182	31	independent	independent	JJ
cord-264699-l8db5gll	182	32	of	of	IN
cord-264699-l8db5gll	182	33	human	human	JJ
cord-264699-l8db5gll	182	34	T	T	NNP
cord-264699-l8db5gll	182	35	-	-	HYPH
cord-264699-l8db5gll	182	36	cell	cell	NN
cord-264699-l8db5gll	182	37	lymphotropic	lymphotropic	NNP
cord-264699-l8db5gll	182	38	virus	virus	NN
cord-264699-l8db5gll	182	39	type-1	type-1	NNP
cord-264699-l8db5gll	182	40	tax	tax	NN
cord-264699-l8db5gll	182	41	expression	expression	NN
cord-264699-l8db5gll	183	1	Metabolic	metabolic	JJ
cord-264699-l8db5gll	183	2	abnormalities	abnormality	NNS
cord-264699-l8db5gll	183	3	and	and	CC
cord-264699-l8db5gll	183	4	cardiovascular	cardiovascular	JJ
cord-264699-l8db5gll	183	5	disease	disease	NN
cord-264699-l8db5gll	183	6	risk	risk	NN
cord-264699-l8db5gll	183	7	factors	factor	NNS
cord-264699-l8db5gll	183	8	in	in	IN
cord-264699-l8db5gll	183	9	adults	adult	NNS
cord-264699-l8db5gll	183	10	with	with	IN
cord-264699-l8db5gll	183	11	human	human	JJ
cord-264699-l8db5gll	183	12	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	183	13	virus	virus	NN
cord-264699-l8db5gll	183	14	infection	infection	NN
cord-264699-l8db5gll	183	15	and	and	CC
cord-264699-l8db5gll	183	16	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	183	17	Metabolic	metabolic	JJ
cord-264699-l8db5gll	183	18	complications	complication	NNS
cord-264699-l8db5gll	183	19	associated	associate	VBN
cord-264699-l8db5gll	183	20	with	with	IN
cord-264699-l8db5gll	183	21	antiretroviral	antiretroviral	JJ
cord-264699-l8db5gll	183	22	therapy	therapy	NN
cord-264699-l8db5gll	183	23	Metabolic	metabolic	JJ
cord-264699-l8db5gll	183	24	disorders	disorder	NNS
cord-264699-l8db5gll	183	25	among	among	IN
cord-264699-l8db5gll	183	26	HIV	HIV	NNP
cord-264699-l8db5gll	183	27	-	-	HYPH
cord-264699-l8db5gll	183	28	infected	infect	VBN
cord-264699-l8db5gll	183	29	patients	patient	NNS
cord-264699-l8db5gll	183	30	treated	treat	VBN
cord-264699-l8db5gll	183	31	with	with	IN
cord-264699-l8db5gll	183	32	protease	protease	NN
cord-264699-l8db5gll	183	33	inhibitors	inhibitor	NNS
cord-264699-l8db5gll	183	34	:	:	:
cord-264699-l8db5gll	183	35	a	a	DT
cord-264699-l8db5gll	183	36	review	review	NN
cord-264699-l8db5gll	183	37	HIV	HIV	NNP
cord-264699-l8db5gll	183	38	-	-	HYPH
cord-264699-l8db5gll	183	39	associated	associate	VBN
cord-264699-l8db5gll	183	40	lipodystrophy	lipodystrophy	NNP
cord-264699-l8db5gll	183	41	syndrome	syndrome	NN
cord-264699-l8db5gll	183	42	Human	human	JJ
cord-264699-l8db5gll	183	43	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	183	44	virus	virus	NN
cord-264699-l8db5gll	183	45	type-1	type-1	NN
cord-264699-l8db5gll	183	46	accessory	accessory	NN
cord-264699-l8db5gll	183	47	protein	protein	NN
cord-264699-l8db5gll	183	48	Vpr	Vpr	NNP
cord-264699-l8db5gll	183	49	:	:	:
cord-264699-l8db5gll	183	50	a	a	DT
cord-264699-l8db5gll	183	51	causative	causative	JJ
cord-264699-l8db5gll	183	52	agent	agent	NN
cord-264699-l8db5gll	183	53	of	of	IN
cord-264699-l8db5gll	183	54	the	the	DT
cord-264699-l8db5gll	183	55	AIDS	AIDS	NNP
cord-264699-l8db5gll	183	56	-	-	HYPH
cord-264699-l8db5gll	183	57	related	relate	VBN
cord-264699-l8db5gll	183	58	insulin	insulin	NN
cord-264699-l8db5gll	183	59	resistance	resistance	NN
cord-264699-l8db5gll	183	60	/	/	SYM
cord-264699-l8db5gll	183	61	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	183	62	syndrome	syndrome	NN
cord-264699-l8db5gll	183	63	?	?	.
cord-264699-l8db5gll	184	1	Endocrine	endocrine	JJ
cord-264699-l8db5gll	184	2	and	and	CC
cord-264699-l8db5gll	184	3	metabolic	metabolic	JJ
cord-264699-l8db5gll	184	4	evaluation	evaluation	NN
cord-264699-l8db5gll	184	5	of	of	IN
cord-264699-l8db5gll	184	6	human	human	JJ
cord-264699-l8db5gll	184	7	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	184	8	virus	virus	NN
cord-264699-l8db5gll	184	9	-	-	HYPH
cord-264699-l8db5gll	184	10	infected	infect	VBN
cord-264699-l8db5gll	184	11	patients	patient	NNS
cord-264699-l8db5gll	184	12	with	with	IN
cord-264699-l8db5gll	184	13	evidence	evidence	NN
cord-264699-l8db5gll	184	14	of	of	IN
cord-264699-l8db5gll	184	15	protease	protease	JJ
cord-264699-l8db5gll	184	16	inhibitor	inhibitor	NN
cord-264699-l8db5gll	184	17	-	-	HYPH
cord-264699-l8db5gll	184	18	associated	associate	VBN
cord-264699-l8db5gll	184	19	lipodystrophy	lipodystrophy	NN
cord-264699-l8db5gll	184	20	AIDS	AIDS	NNP
cord-264699-l8db5gll	184	21	-	-	HYPH
cord-264699-l8db5gll	184	22	related	relate	VBN
cord-264699-l8db5gll	184	23	Kaposi	Kaposi	NNP
cord-264699-l8db5gll	184	24	's	's	POS
cord-264699-l8db5gll	184	25	sarcoma	sarcoma	NN
cord-264699-l8db5gll	184	26	:	:	:
cord-264699-l8db5gll	184	27	evidence	evidence	NN
cord-264699-l8db5gll	184	28	for	for	IN
cord-264699-l8db5gll	184	29	direct	direct	JJ
cord-264699-l8db5gll	184	30	stimulatory	stimulatory	JJ
cord-264699-l8db5gll	184	31	effect	effect	NN
cord-264699-l8db5gll	184	32	of	of	IN
cord-264699-l8db5gll	184	33	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	184	34	on	on	IN
cord-264699-l8db5gll	184	35	cell	cell	NN
cord-264699-l8db5gll	184	36	proliferation	proliferation	NN
cord-264699-l8db5gll	184	37	Partner	partner	NN
cord-264699-l8db5gll	184	38	molecules	molecule	NNS
cord-264699-l8db5gll	184	39	of	of	IN
cord-264699-l8db5gll	184	40	accessory	accessory	NN
cord-264699-l8db5gll	184	41	protein	protein	NN
cord-264699-l8db5gll	184	42	Vpr	Vpr	NNP
cord-264699-l8db5gll	184	43	of	of	IN
cord-264699-l8db5gll	184	44	the	the	DT
cord-264699-l8db5gll	184	45	human	human	JJ
cord-264699-l8db5gll	184	46	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	184	47	virus	virus	NN
cord-264699-l8db5gll	184	48	type	type	NN
cord-264699-l8db5gll	184	49	1	1	CD
cord-264699-l8db5gll	184	50	Human	Human	NNP
cord-264699-l8db5gll	184	51	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	184	52	virus	virus	NN
cord-264699-l8db5gll	184	53	type	type	NN
cord-264699-l8db5gll	184	54	1	1	CD
cord-264699-l8db5gll	185	1	(	(	-LRB-
cord-264699-l8db5gll	185	2	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	185	3	)	)	-RRB-
cord-264699-l8db5gll	185	4	accessory	accessory	NN
cord-264699-l8db5gll	185	5	protein	protein	NN
cord-264699-l8db5gll	185	6	Vpr	Vpr	NNP
cord-264699-l8db5gll	185	7	induces	induce	VBZ
cord-264699-l8db5gll	185	8	transcription	transcription	NN
cord-264699-l8db5gll	185	9	of	of	IN
cord-264699-l8db5gll	185	10	the	the	DT
cord-264699-l8db5gll	185	11	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	185	12	and	and	CC
cord-264699-l8db5gll	185	13	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	185	14	-	-	HYPH
cord-264699-l8db5gll	185	15	responsive	responsive	JJ
cord-264699-l8db5gll	185	16	promoters	promoter	NNS
cord-264699-l8db5gll	185	17	by	by	IN
cord-264699-l8db5gll	185	18	binding	bind	VBG
cord-264699-l8db5gll	185	19	directly	directly	RB
cord-264699-l8db5gll	185	20	to	to	IN
cord-264699-l8db5gll	185	21	p300	p300	NNP
cord-264699-l8db5gll	185	22	/	/	SYM
cord-264699-l8db5gll	185	23	CBP	CBP	NNP
cord-264699-l8db5gll	185	24	coactivators	coactivator	NNS
cord-264699-l8db5gll	186	1	The	the	DT
cord-264699-l8db5gll	186	2	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	186	3	virion	virion	NN
cord-264699-l8db5gll	186	4	-	-	HYPH
cord-264699-l8db5gll	186	5	associated	associate	VBN
cord-264699-l8db5gll	186	6	protein	protein	NN
cord-264699-l8db5gll	186	7	vpr	vpr	NNP
cord-264699-l8db5gll	186	8	is	be	VBZ
cord-264699-l8db5gll	186	9	a	a	DT
cord-264699-l8db5gll	186	10	coactivator	coactivator	NN
cord-264699-l8db5gll	186	11	of	of	IN
cord-264699-l8db5gll	186	12	the	the	DT
cord-264699-l8db5gll	186	13	human	human	JJ
cord-264699-l8db5gll	186	14	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	186	15	receptor	receptor	NN
cord-264699-l8db5gll	186	16	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	186	17	protein	protein	NN
cord-264699-l8db5gll	186	18	Vpr	Vpr	NNP
cord-264699-l8db5gll	187	1	suppresses	suppress	VBZ
cord-264699-l8db5gll	187	2	IL-12	IL-12	NNP
cord-264699-l8db5gll	187	3	production	production	NN
cord-264699-l8db5gll	187	4	from	from	IN
cord-264699-l8db5gll	187	5	human	human	JJ
cord-264699-l8db5gll	187	6	monocytes	monocyte	NNS
cord-264699-l8db5gll	187	7	by	by	IN
cord-264699-l8db5gll	187	8	enhancing	enhance	VBG
cord-264699-l8db5gll	187	9	glucocorticoid	glucocorticoid	NN
cord-264699-l8db5gll	187	10	action	action	NN
cord-264699-l8db5gll	187	11	:	:	:
cord-264699-l8db5gll	187	12	potential	potential	JJ
cord-264699-l8db5gll	187	13	implications	implication	NNS
cord-264699-l8db5gll	187	14	of	of	IN
cord-264699-l8db5gll	187	15	Vpr	Vpr	NNP
cord-264699-l8db5gll	187	16	coactivator	coactivator	NN
cord-264699-l8db5gll	187	17	activity	activity	NN
cord-264699-l8db5gll	187	18	for	for	IN
cord-264699-l8db5gll	187	19	the	the	DT
cord-264699-l8db5gll	187	20	innate	innate	JJ
cord-264699-l8db5gll	187	21	and	and	CC
cord-264699-l8db5gll	187	22	cellular	cellular	JJ
cord-264699-l8db5gll	187	23	immunity	immunity	NN
cord-264699-l8db5gll	187	24	deficits	deficit	NNS
cord-264699-l8db5gll	187	25	observed	observe	VBN
cord-264699-l8db5gll	187	26	in	in	IN
cord-264699-l8db5gll	187	27	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	187	28	infection	infection	NN
cord-264699-l8db5gll	187	29	CBP	CBP	NNP
cord-264699-l8db5gll	187	30	/	/	SYM
cord-264699-l8db5gll	187	31	p300	p300	NN
cord-264699-l8db5gll	187	32	in	in	IN
cord-264699-l8db5gll	187	33	cell	cell	NN
cord-264699-l8db5gll	187	34	growth	growth	NN
cord-264699-l8db5gll	187	35	,	,	,
cord-264699-l8db5gll	187	36	transformation	transformation	NN
cord-264699-l8db5gll	187	37	,	,	,
cord-264699-l8db5gll	187	38	and	and	CC
cord-264699-l8db5gll	187	39	development	development	NN
cord-264699-l8db5gll	187	40	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	187	41	Vpr	Vpr	NNP
cord-264699-l8db5gll	187	42	displays	display	VBZ
cord-264699-l8db5gll	187	43	natural	natural	JJ
cord-264699-l8db5gll	187	44	proteintransducing	proteintransduce	VBG
cord-264699-l8db5gll	187	45	properties	property	NNS
cord-264699-l8db5gll	187	46	:	:	:
cord-264699-l8db5gll	187	47	implications	implication	NNS
cord-264699-l8db5gll	187	48	for	for	IN
cord-264699-l8db5gll	187	49	viral	viral	JJ
cord-264699-l8db5gll	187	50	pathogenesis	pathogenesis	NN
cord-264699-l8db5gll	187	51	Nuclear	nuclear	JJ
cord-264699-l8db5gll	187	52	receptor	receptor	NN
cord-264699-l8db5gll	188	1	coactivator	coactivator	NN
cord-264699-l8db5gll	188	2	p160	p160	NN
cord-264699-l8db5gll	188	3	proteins	protein	NNS
cord-264699-l8db5gll	188	4	enhance	enhance	VBP
cord-264699-l8db5gll	188	5	the	the	DT
cord-264699-l8db5gll	188	6	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	188	7	long	long	JJ
cord-264699-l8db5gll	188	8	terminal	terminal	NN
cord-264699-l8db5gll	188	9	repeat	repeat	NN
cord-264699-l8db5gll	188	10	promoter	promoter	NN
cord-264699-l8db5gll	188	11	by	by	IN
cord-264699-l8db5gll	188	12	bridging	bridge	VBG
cord-264699-l8db5gll	188	13	promoter	promoter	NN
cord-264699-l8db5gll	188	14	-	-	HYPH
cord-264699-l8db5gll	188	15	bound	bind	VBN
cord-264699-l8db5gll	188	16	factors	factor	NNS
cord-264699-l8db5gll	188	17	and	and	CC
cord-264699-l8db5gll	188	18	the	the	DT
cord-264699-l8db5gll	188	19	Tat	Tat	NNP
cord-264699-l8db5gll	188	20	-	-	HYPH
cord-264699-l8db5gll	188	21	P	P	NNP
cord-264699-l8db5gll	188	22	-	-	HYPH
cord-264699-l8db5gll	188	23	TEFb	TEFb	NNS
cord-264699-l8db5gll	188	24	complex	complex	JJ
cord-264699-l8db5gll	188	25	Tat	tat	NN
cord-264699-l8db5gll	188	26	-	-	HYPH
cord-264699-l8db5gll	188	27	mediated	mediate	VBN
cord-264699-l8db5gll	188	28	delivery	delivery	NN
cord-264699-l8db5gll	188	29	of	of	IN
cord-264699-l8db5gll	188	30	heterologous	heterologous	JJ
cord-264699-l8db5gll	188	31	proteins	protein	NNS
cord-264699-l8db5gll	188	32	into	into	IN
cord-264699-l8db5gll	189	1	cells	cell	NNS
cord-264699-l8db5gll	189	2	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	189	3	accessory	accessory	NN
cord-264699-l8db5gll	189	4	protein	protein	NN
cord-264699-l8db5gll	189	5	Vpr	Vpr	NNP
cord-264699-l8db5gll	189	6	inhibits	inhibit	VBZ
cord-264699-l8db5gll	189	7	the	the	DT
cord-264699-l8db5gll	189	8	effect	effect	NN
cord-264699-l8db5gll	189	9	of	of	IN
cord-264699-l8db5gll	189	10	insulin	insulin	NN
cord-264699-l8db5gll	189	11	on	on	IN
cord-264699-l8db5gll	189	12	the	the	DT
cord-264699-l8db5gll	189	13	Foxo	Foxo	NNP
cord-264699-l8db5gll	189	14	subfamily	subfamily	NN
cord-264699-l8db5gll	189	15	of	of	IN
cord-264699-l8db5gll	189	16	forkhead	forkhead	NN
cord-264699-l8db5gll	189	17	transcription	transcription	NN
cord-264699-l8db5gll	189	18	factors	factor	NNS
cord-264699-l8db5gll	189	19	by	by	IN
cord-264699-l8db5gll	189	20	interfering	interfere	VBG
cord-264699-l8db5gll	189	21	with	with	IN
cord-264699-l8db5gll	189	22	their	-PRON-	PRP$
cord-264699-l8db5gll	189	23	binding	binding	NN
cord-264699-l8db5gll	189	24	to	to	IN
cord-264699-l8db5gll	189	25	14	14	CD
cord-264699-l8db5gll	189	26	-	-	SYM
cord-264699-l8db5gll	189	27	3	3	CD
cord-264699-l8db5gll	189	28	-	-	SYM
cord-264699-l8db5gll	189	29	3	3	CD
cord-264699-l8db5gll	189	30	proteins	protein	NNS
cord-264699-l8db5gll	189	31	:	:	:
cord-264699-l8db5gll	189	32	potential	potential	JJ
cord-264699-l8db5gll	189	33	clinical	clinical	JJ
cord-264699-l8db5gll	189	34	implications	implication	NNS
cord-264699-l8db5gll	189	35	regarding	regard	VBG
cord-264699-l8db5gll	189	36	the	the	DT
cord-264699-l8db5gll	189	37	insulin	insulin	NN
cord-264699-l8db5gll	189	38	resistance	resistance	NN
cord-264699-l8db5gll	189	39	of	of	IN
cord-264699-l8db5gll	189	40	HIV-1-infected	hiv-1-infecte	VBN
cord-264699-l8db5gll	189	41	patients	patient	NNS
cord-264699-l8db5gll	189	42	Vpr	Vpr	NNP
cord-264699-l8db5gll	189	43	protein	protein	NN
cord-264699-l8db5gll	189	44	of	of	IN
cord-264699-l8db5gll	189	45	human	human	JJ
cord-264699-l8db5gll	189	46	immunodeficiency	immunodeficiency	NN
cord-264699-l8db5gll	189	47	virus	virus	NN
cord-264699-l8db5gll	189	48	type	type	NN
cord-264699-l8db5gll	189	49	1	1	CD
cord-264699-l8db5gll	189	50	binds	bind	VBZ
cord-264699-l8db5gll	189	51	to	to	IN
cord-264699-l8db5gll	189	52	14	14	CD
cord-264699-l8db5gll	189	53	-	-	SYM
cord-264699-l8db5gll	189	54	3	3	CD
cord-264699-l8db5gll	189	55	-	-	SYM
cord-264699-l8db5gll	189	56	3	3	CD
cord-264699-l8db5gll	189	57	proteins	protein	NNS
cord-264699-l8db5gll	189	58	and	and	CC
cord-264699-l8db5gll	189	59	facilitates	facilitate	VBZ
cord-264699-l8db5gll	189	60	complex	complex	JJ
cord-264699-l8db5gll	189	61	formation	formation	NN
cord-264699-l8db5gll	189	62	with	with	IN
cord-264699-l8db5gll	189	63	Cdc25C	cdc25c	NN
cord-264699-l8db5gll	189	64	:	:	:
cord-264699-l8db5gll	189	65	implications	implication	NNS
cord-264699-l8db5gll	189	66	for	for	IN
cord-264699-l8db5gll	189	67	cell	cell	NN
cord-264699-l8db5gll	189	68	cycle	cycle	NN
cord-264699-l8db5gll	189	69	arrest	arrest	NN
cord-264699-l8db5gll	189	70	FoxO	FoxO	NNP
cord-264699-l8db5gll	189	71	proteins	protein	NNS
cord-264699-l8db5gll	189	72	in	in	IN
cord-264699-l8db5gll	189	73	insulin	insulin	NN
cord-264699-l8db5gll	189	74	action	action	NN
cord-264699-l8db5gll	189	75	and	and	CC
cord-264699-l8db5gll	189	76	metabolism	metabolism	NN
cord-264699-l8db5gll	190	1	Paget	Paget	NNP
cord-264699-l8db5gll	190	2	disease	disease	NN
cord-264699-l8db5gll	190	3	of	of	IN
cord-264699-l8db5gll	190	4	bone	bone	NN
cord-264699-l8db5gll	190	5	Measles	Measles	NNP
cord-264699-l8db5gll	190	6	virus	virus	NN
cord-264699-l8db5gll	190	7	RNA	RNA	NNP
cord-264699-l8db5gll	190	8	detected	detect	VBD
cord-264699-l8db5gll	190	9	in	in	IN
cord-264699-l8db5gll	190	10	Paget	Paget	NNP
cord-264699-l8db5gll	190	11	's	's	POS
cord-264699-l8db5gll	190	12	disease	disease	NN
cord-264699-l8db5gll	190	13	bone	bone	NN
cord-264699-l8db5gll	190	14	tissue	tissue	NN
cord-264699-l8db5gll	190	15	by	by	IN
cord-264699-l8db5gll	190	16	in	in	IN
cord-264699-l8db5gll	190	17	situ	situ	NN
cord-264699-l8db5gll	190	18	hybridization	hybridization	NN
cord-264699-l8db5gll	190	19	Expression	expression	NN
cord-264699-l8db5gll	190	20	of	of	IN
cord-264699-l8db5gll	190	21	measles	measle	NNS
cord-264699-l8db5gll	190	22	virus	virus	NN
cord-264699-l8db5gll	190	23	nucleocapsid	nucleocapsid	NNP
cord-264699-l8db5gll	190	24	protein	protein	NN
cord-264699-l8db5gll	190	25	in	in	IN
cord-264699-l8db5gll	190	26	osteoclasts	osteoclast	NNS
cord-264699-l8db5gll	190	27	induces	induce	VBZ
cord-264699-l8db5gll	190	28	Paget	Paget	NNP
cord-264699-l8db5gll	190	29	's	's	POS
cord-264699-l8db5gll	190	30	disease	disease	NN
cord-264699-l8db5gll	190	31	-	-	HYPH
cord-264699-l8db5gll	190	32	like	like	JJ
cord-264699-l8db5gll	190	33	bone	bone	NN
cord-264699-l8db5gll	190	34	lesions	lesion	NNS
cord-264699-l8db5gll	190	35	in	in	IN
cord-264699-l8db5gll	190	36	mice	mouse	NNS
cord-264699-l8db5gll	191	1	Textbook	Textbook	NNP
cord-264699-l8db5gll	191	2	of	of	IN
cord-264699-l8db5gll	191	3	Human	Human	NNP
cord-264699-l8db5gll	191	4	Virology	Virology	NNP
cord-264699-l8db5gll	192	1	The	the	DT
cord-264699-l8db5gll	192	2	multifunctional	multifunctional	JJ
cord-264699-l8db5gll	192	3	role	role	NN
cord-264699-l8db5gll	192	4	of	of	IN
cord-264699-l8db5gll	192	5	E1A	e1a	NN
cord-264699-l8db5gll	192	6	in	in	IN
cord-264699-l8db5gll	192	7	the	the	DT
cord-264699-l8db5gll	192	8	transcriptional	transcriptional	JJ
cord-264699-l8db5gll	192	9	regulation	regulation	NN
cord-264699-l8db5gll	192	10	of	of	IN
cord-264699-l8db5gll	192	11	CREB	CREB	NNP
cord-264699-l8db5gll	192	12	/	/	SYM
cord-264699-l8db5gll	192	13	CBP	CBP	NNP
cord-264699-l8db5gll	192	14	-	-	HYPH
cord-264699-l8db5gll	192	15	dependent	dependent	JJ
cord-264699-l8db5gll	192	16	target	target	NN
cord-264699-l8db5gll	192	17	genes	gene	NNS
cord-264699-l8db5gll	192	18	CtBP	CtBP	NNP
cord-264699-l8db5gll	192	19	,	,	,
cord-264699-l8db5gll	192	20	an	an	DT
cord-264699-l8db5gll	192	21	unconventional	unconventional	JJ
cord-264699-l8db5gll	192	22	transcriptional	transcriptional	NN
cord-264699-l8db5gll	192	23	corepressor	corepressor	NN
cord-264699-l8db5gll	192	24	in	in	IN
cord-264699-l8db5gll	192	25	development	development	NN
cord-264699-l8db5gll	192	26	and	and	CC
cord-264699-l8db5gll	192	27	oncogenesis	oncogenesis	NN
cord-264699-l8db5gll	192	28	Severe	severe	JJ
cord-264699-l8db5gll	192	29	acute	acute	JJ
cord-264699-l8db5gll	192	30	respiratory	respiratory	JJ
cord-264699-l8db5gll	192	31	syndrome	syndrome	NN
cord-264699-l8db5gll	192	32	(	(	-LRB-
cord-264699-l8db5gll	192	33	SARS	SARS	NNP
cord-264699-l8db5gll	192	34	)	)	-RRB-
cord-264699-l8db5gll	192	35	:	:	:
cord-264699-l8db5gll	192	36	development	development	NN
cord-264699-l8db5gll	192	37	of	of	IN
cord-264699-l8db5gll	192	38	diagnostics	diagnostic	NNS
cord-264699-l8db5gll	192	39	and	and	CC
cord-264699-l8db5gll	192	40	antivirals	antiviral	NNS
cord-264699-l8db5gll	193	1	A	a	DT
cord-264699-l8db5gll	193	2	novel	novel	JJ
cord-264699-l8db5gll	193	3	coronavirus	coronavirus	NN
cord-264699-l8db5gll	193	4	associated	associate	VBN
cord-264699-l8db5gll	193	5	with	with	IN
cord-264699-l8db5gll	193	6	severe	severe	JJ
cord-264699-l8db5gll	193	7	acute	acute	JJ
cord-264699-l8db5gll	193	8	respiratory	respiratory	JJ
cord-264699-l8db5gll	193	9	syndrome	syndrome	NN
cord-264699-l8db5gll	193	10	Angiotensin	angiotensin	NN
cord-264699-l8db5gll	193	11	-	-	HYPH
cord-264699-l8db5gll	193	12	converting	convert	VBG
cord-264699-l8db5gll	193	13	enzyme	enzyme	NN
cord-264699-l8db5gll	193	14	2	2	CD
cord-264699-l8db5gll	193	15	is	be	VBZ
cord-264699-l8db5gll	193	16	a	a	DT
cord-264699-l8db5gll	193	17	functional	functional	JJ
cord-264699-l8db5gll	193	18	receptor	receptor	NN
cord-264699-l8db5gll	193	19	for	for	IN
cord-264699-l8db5gll	193	20	the	the	DT
cord-264699-l8db5gll	193	21	SARS	SARS	NNP
cord-264699-l8db5gll	193	22	coronavirus	coronavirus	NN
cord-264699-l8db5gll	194	1	A	a	DT
cord-264699-l8db5gll	195	1	novel	novel	NNP
cord-264699-l8db5gll	195	2	angiotensin	angiotensin	NN
cord-264699-l8db5gll	195	3	-	-	HYPH
cord-264699-l8db5gll	195	4	converting	convert	VBG
cord-264699-l8db5gll	195	5	enzymerelated	enzymerelated	JJ
cord-264699-l8db5gll	195	6	carboxypeptidase	carboxypeptidase	NN
cord-264699-l8db5gll	195	7	(	(	-LRB-
cord-264699-l8db5gll	195	8	ACE2	ACE2	NNP
cord-264699-l8db5gll	195	9	)	)	-RRB-
cord-264699-l8db5gll	195	10	converts	convert	VBZ
cord-264699-l8db5gll	195	11	angiotensin	angiotensin	NN
cord-264699-l8db5gll	195	12	I	-PRON-	PRP
cord-264699-l8db5gll	195	13	to	to	IN
cord-264699-l8db5gll	195	14	angiotensin	angiotensin	NN
cord-264699-l8db5gll	195	15	1	1	CD
cord-264699-l8db5gll	196	1	-9	-9	NNP
cord-264699-l8db5gll	196	2	A	a	DT
cord-264699-l8db5gll	196	3	human	human	JJ
cord-264699-l8db5gll	196	4	homolog	homolog	NN
cord-264699-l8db5gll	196	5	of	of	IN
cord-264699-l8db5gll	196	6	angiotensin	angiotensin	NN
cord-264699-l8db5gll	196	7	-	-	HYPH
cord-264699-l8db5gll	196	8	converting	convert	VBG
cord-264699-l8db5gll	196	9	enzyme	enzyme	NN
cord-264699-l8db5gll	196	10	.	.	.
cord-264699-l8db5gll	197	1	Cloning	clone	VBG
cord-264699-l8db5gll	197	2	and	and	CC
cord-264699-l8db5gll	197	3	functional	functional	JJ
cord-264699-l8db5gll	197	4	expression	expression	NN
cord-264699-l8db5gll	197	5	as	as	IN
cord-264699-l8db5gll	197	6	a	a	DT
cord-264699-l8db5gll	197	7	captopril	captopril	NN
cord-264699-l8db5gll	197	8	-	-	HYPH
cord-264699-l8db5gll	197	9	insensitive	insensitive	JJ
cord-264699-l8db5gll	197	10	carboxypeptidase	carboxypeptidase	NN
cord-264699-l8db5gll	197	11	Angiotensin	Angiotensin	NNP
cord-264699-l8db5gll	197	12	-	-	HYPH
cord-264699-l8db5gll	197	13	converting	convert	VBG
cord-264699-l8db5gll	197	14	enzyme	enzyme	NN
cord-264699-l8db5gll	197	15	2	2	CD
cord-264699-l8db5gll	197	16	in	in	IN
cord-264699-l8db5gll	197	17	lung	lung	NN
cord-264699-l8db5gll	197	18	diseases	disease	NNS
cord-264699-l8db5gll	198	1	Angiotensin	angiotensin	NN
cord-264699-l8db5gll	198	2	-	-	HYPH
cord-264699-l8db5gll	198	3	converting	convert	VBG
cord-264699-l8db5gll	198	4	enzyme	enzyme	NN
cord-264699-l8db5gll	198	5	2	2	CD
cord-264699-l8db5gll	198	6	is	be	VBZ
cord-264699-l8db5gll	198	7	an	an	DT
cord-264699-l8db5gll	198	8	essential	essential	JJ
cord-264699-l8db5gll	198	9	regulator	regulator	NN
cord-264699-l8db5gll	198	10	of	of	IN
cord-264699-l8db5gll	198	11	heart	heart	NN
cord-264699-l8db5gll	198	12	function	function	NN
cord-264699-l8db5gll	199	1	Pleiotropic	Pleiotropic	NNP
cord-264699-l8db5gll	199	2	AT1	AT1	NNP
cord-264699-l8db5gll	199	3	receptor	receptor	NN
cord-264699-l8db5gll	199	4	signaling	signal	VBG
cord-264699-l8db5gll	199	5	pathways	pathway	NNS
cord-264699-l8db5gll	199	6	mediating	mediate	VBG
cord-264699-l8db5gll	199	7	physiological	physiological	JJ
cord-264699-l8db5gll	199	8	and	and	CC
cord-264699-l8db5gll	199	9	pathogenic	pathogenic	JJ
cord-264699-l8db5gll	199	10	actions	action	NNS
cord-264699-l8db5gll	199	11	of	of	IN
cord-264699-l8db5gll	200	1	angiotensin	angiotensin	NN
cord-264699-l8db5gll	200	2	II	II	NNP
cord-264699-l8db5gll	200	3	A	a	DT
cord-264699-l8db5gll	200	4	crucial	crucial	JJ
cord-264699-l8db5gll	200	5	role	role	NN
cord-264699-l8db5gll	200	6	of	of	IN
cord-264699-l8db5gll	200	7	angiotensin	angiotensin	NN
cord-264699-l8db5gll	200	8	converting	convert	VBG
cord-264699-l8db5gll	200	9	enzyme	enzyme	NN
cord-264699-l8db5gll	200	10	2	2	CD
cord-264699-l8db5gll	200	11	(	(	-LRB-
cord-264699-l8db5gll	200	12	ACE2	ACE2	NNP
cord-264699-l8db5gll	200	13	)	)	-RRB-
cord-264699-l8db5gll	200	14	in	in	IN
cord-264699-l8db5gll	200	15	SARS	SARS	NNP
cord-264699-l8db5gll	200	16	coronavirus	coronavirus	NN
cord-264699-l8db5gll	200	17	-	-	HYPH
cord-264699-l8db5gll	200	18	induced	induce	VBN
cord-264699-l8db5gll	200	19	lung	lung	NN
cord-264699-l8db5gll	200	20	injury	injury	NN
cord-264699-l8db5gll	200	21	HIV	HIV	NNP
cord-264699-l8db5gll	200	22	pathogenesis	pathogenesis	NN
cord-264699-l8db5gll	200	23	:	:	:
cord-264699-l8db5gll	200	24	knowledge	knowledge	NN
cord-264699-l8db5gll	200	25	gained	gain	VBN
cord-264699-l8db5gll	200	26	after	after	IN
cord-264699-l8db5gll	200	27	two	two	CD
cord-264699-l8db5gll	200	28	decades	decade	NNS
cord-264699-l8db5gll	200	29	of	of	IN
cord-264699-l8db5gll	200	30	research	research	NN
cord-264699-l8db5gll	200	31	HIV	HIV	NNP
cord-264699-l8db5gll	200	32	vaccines	vaccine	VBZ
cord-264699-l8db5gll	200	33	Antivirals	Antivirals	NNPS
cord-264699-l8db5gll	200	34	for	for	IN
cord-264699-l8db5gll	200	35	the	the	DT
cord-264699-l8db5gll	200	36	treatment	treatment	NN
cord-264699-l8db5gll	200	37	of	of	IN
cord-264699-l8db5gll	200	38	herpesvirus	herpesvirus	NN
cord-264699-l8db5gll	200	39	infections	infection	NNS
cord-264699-l8db5gll	200	40	Neuraminidase	Neuraminidase	NNP
cord-264699-l8db5gll	200	41	inhibitors	inhibitor	NNS
cord-264699-l8db5gll	200	42	for	for	IN
cord-264699-l8db5gll	200	43	influenza	influenza	NN
cord-264699-l8db5gll	200	44	HIV-1	HIV-1	NNP
cord-264699-l8db5gll	200	45	Tat	Tat	NNP
cord-264699-l8db5gll	200	46	-	-	HYPH
cord-264699-l8db5gll	200	47	based	base	VBN
cord-264699-l8db5gll	200	48	vaccines	vaccine	NNS
cord-264699-l8db5gll	200	49	:	:	:
cord-264699-l8db5gll	200	50	from	from	IN
cord-264699-l8db5gll	200	51	basic	basic	JJ
cord-264699-l8db5gll	200	52	science	science	NN
cord-264699-l8db5gll	200	53	to	to	IN
cord-264699-l8db5gll	200	54	clinical	clinical	JJ
cord-264699-l8db5gll	200	55	trials	trial	NNS
cord-264699-l8db5gll	200	56	Pituitary	Pituitary	NNP
cord-264699-l8db5gll	200	57	-	-	HYPH
cord-264699-l8db5gll	200	58	testicular	testicular	NN
cord-264699-l8db5gll	200	59	interrelationships	interrelationship	NNS
cord-264699-l8db5gll	200	60	in	in	IN
cord-264699-l8db5gll	200	61	mumps	mumps	NN
cord-264699-l8db5gll	200	62	orchitis	orchitis	NN
cord-264699-l8db5gll	200	63	and	and	CC
cord-264699-l8db5gll	200	64	other	other	JJ
cord-264699-l8db5gll	200	65	viral	viral	JJ
cord-264699-l8db5gll	200	66	infections	infection	NNS
cord-264699-l8db5gll	200	67	Hypopituitarism	Hypopituitarism	NNP
cord-264699-l8db5gll	200	68	as	as	IN
cord-264699-l8db5gll	200	69	a	a	DT
cord-264699-l8db5gll	200	70	late	late	JJ
cord-264699-l8db5gll	200	71	complication	complication	NN
cord-264699-l8db5gll	200	72	of	of	IN
cord-264699-l8db5gll	200	73	hemorrhagic	hemorrhagic	JJ
cord-264699-l8db5gll	200	74	fever	fever	NN
cord-264699-l8db5gll	200	75	Herpes	Herpes	NNP
cord-264699-l8db5gll	200	76	simplex	simplex	NN
cord-264699-l8db5gll	200	77	virus	virus	NN
cord-264699-l8db5gll	200	78	infections	infection	NNS
cord-264699-l8db5gll	200	79	in	in	IN
cord-264699-l8db5gll	200	80	neonates	neonate	NNS
cord-264699-l8db5gll	200	81	and	and	CC
cord-264699-l8db5gll	200	82	early	early	JJ
cord-264699-l8db5gll	200	83	childhood	childhood	NN
cord-264699-l8db5gll	200	84	AIDS	AIDS	NNP
cord-264699-l8db5gll	200	85	/	/	SYM
cord-264699-l8db5gll	200	86	HPA	HPA	NNP
cord-264699-l8db5gll	200	87	axis	axis	NN
cord-264699-l8db5gll	200	88	Therapeutic	therapeutic	JJ
cord-264699-l8db5gll	200	89	management	management	NN
cord-264699-l8db5gll	200	90	of	of	IN
cord-264699-l8db5gll	200	91	extrahepatic	extrahepatic	JJ
cord-264699-l8db5gll	200	92	manifestations	manifestation	NNS
cord-264699-l8db5gll	200	93	in	in	IN
cord-264699-l8db5gll	200	94	patients	patient	NNS
cord-264699-l8db5gll	200	95	with	with	IN
cord-264699-l8db5gll	200	96	chronic	chronic	JJ
cord-264699-l8db5gll	200	97	hepatitis	hepatitis	NN
cord-264699-l8db5gll	200	98	C	c	NN
cord-264699-l8db5gll	200	99	virus	virus	NN
cord-264699-l8db5gll	200	100	infection	infection	NN
cord-264699-l8db5gll	200	101	Autoimmunity	Autoimmunity	NNP
cord-264699-l8db5gll	200	102	in	in	IN
cord-264699-l8db5gll	200	103	congenital	congenital	JJ
cord-264699-l8db5gll	200	104	rubella	rubella	NN
cord-264699-l8db5gll	200	105	syndrome	syndrome	NN
cord-264699-l8db5gll	201	1	Molecular	molecular	JJ
cord-264699-l8db5gll	201	2	mimicry	mimicry	NN
cord-264699-l8db5gll	201	3	,	,	,
cord-264699-l8db5gll	201	4	microbial	microbial	JJ
cord-264699-l8db5gll	201	5	infection	infection	NN
cord-264699-l8db5gll	201	6	,	,	,
cord-264699-l8db5gll	201	7	and	and	CC
cord-264699-l8db5gll	201	8	autoimmune	autoimmune	JJ
cord-264699-l8db5gll	201	9	disease	disease	NN
cord-264699-l8db5gll	201	10	:	:	:
cord-264699-l8db5gll	201	11	evolution	evolution	NN
cord-264699-l8db5gll	201	12	of	of	IN
cord-264699-l8db5gll	201	13	the	the	DT
cord-264699-l8db5gll	201	14	concept	concept	NN
cord-264699-l8db5gll	201	15	Infection	infection	NN
cord-264699-l8db5gll	201	16	,	,	,
cord-264699-l8db5gll	201	17	thyroid	thyroid	NN
cord-264699-l8db5gll	201	18	disease	disease	NN
cord-264699-l8db5gll	201	19	,	,	,
cord-264699-l8db5gll	201	20	and	and	CC
cord-264699-l8db5gll	201	21	autoimmunity	autoimmunity	IN
cord-264699-l8db5gll	201	22	Viral	viral	JJ
cord-264699-l8db5gll	201	23	persistence	persistence	NN
cord-264699-l8db5gll	201	24	:	:	:
cord-264699-l8db5gll	201	25	parameters	parameter	NNS
cord-264699-l8db5gll	201	26	,	,	,
cord-264699-l8db5gll	201	27	mechanisms	mechanism	NNS
cord-264699-l8db5gll	201	28	and	and	CC
cord-264699-l8db5gll	201	29	future	future	JJ
cord-264699-l8db5gll	201	30	predictions	prediction	NNS
cord-264699-l8db5gll	201	31	Selective	selective	JJ
cord-264699-l8db5gll	201	32	inhibition	inhibition	NN
cord-264699-l8db5gll	201	33	of	of	IN
cord-264699-l8db5gll	201	34	nuclear	nuclear	JJ
cord-264699-l8db5gll	201	35	steroid	steroid	NN
cord-264699-l8db5gll	201	36	receptor	receptor	NN
cord-264699-l8db5gll	201	37	function	function	NN
cord-264699-l8db5gll	201	38	by	by	IN
cord-264699-l8db5gll	201	39	a	a	DT
cord-264699-l8db5gll	201	40	protein	protein	NN
cord-264699-l8db5gll	201	41	from	from	IN
cord-264699-l8db5gll	201	42	a	a	DT
cord-264699-l8db5gll	201	43	human	human	JJ
cord-264699-l8db5gll	201	44	tumorigenic	tumorigenic	NNP
cord-264699-l8db5gll	201	45	poxvirus	poxvirus	NNP
cord-264699-l8db5gll	201	46	This	this	DT
cord-264699-l8db5gll	201	47	article	article	NN
cord-264699-l8db5gll	201	48	was	be	VBD
cord-264699-l8db5gll	201	49	funded	fund	VBN
cord-264699-l8db5gll	201	50	by	by	IN
cord-264699-l8db5gll	201	51	the	the	DT
cord-264699-l8db5gll	201	52	Intramural	Intramural	NNP
cord-264699-l8db5gll	201	53	Research	Research	NNP
cord-264699-l8db5gll	201	54	Program	Program	NNP
cord-264699-l8db5gll	201	55	of	of	IN
cord-264699-l8db5gll	201	56	the	the	DT
cord-264699-l8db5gll	201	57	National	National	NNP
cord-264699-l8db5gll	201	58	Institute	Institute	NNP
cord-264699-l8db5gll	201	59	of	of	IN
cord-264699-l8db5gll	201	60	Child	Child	NNP
cord-264699-l8db5gll	201	61	Health	Health	NNP
cord-264699-l8db5gll	201	62	and	and	CC
cord-264699-l8db5gll	201	63	Human	Human	NNP
cord-264699-l8db5gll	201	64	Development	Development	NNP
cord-264699-l8db5gll	201	65	,	,	,
cord-264699-l8db5gll	201	66	National	National	NNP
cord-264699-l8db5gll	201	67	Institutes	Institutes	NNPS
cord-264699-l8db5gll	201	68	of	of	IN
cord-264699-l8db5gll	201	69	Health	Health	NNP
cord-264699-l8db5gll	201	70	.	.	.