id	sid	tid	token	lemma	pos
cord-264050-6zpw6itb	1	1	key	key	NN
cord-264050-6zpw6itb	1	2	:	:	:
cord-264050-6zpw6itb	2	1	cord-264050	cord-264050	NNP
cord-264050-6zpw6itb	2	2	-	-	HYPH
cord-264050-6zpw6itb	2	3	6zpw6itb	6zpw6itb	NNP
cord-264050-6zpw6itb	2	4	authors	author	NNS
cord-264050-6zpw6itb	2	5	:	:	:
cord-264050-6zpw6itb	2	6	Pirofski	Pirofski	NNP
cord-264050-6zpw6itb	2	7	,	,	,
cord-264050-6zpw6itb	2	8	Liise	Liise	NNP
cord-264050-6zpw6itb	2	9	-	-	HYPH
cord-264050-6zpw6itb	2	10	anne	anne	NNP
cord-264050-6zpw6itb	2	11	;	;	:
cord-264050-6zpw6itb	2	12	Casadevall	Casadevall	NNP
cord-264050-6zpw6itb	2	13	,	,	,
cord-264050-6zpw6itb	2	14	Arturo	Arturo	NNP
cord-264050-6zpw6itb	2	15	title	title	NN
cord-264050-6zpw6itb	2	16	:	:	:
cord-264050-6zpw6itb	3	1	Immune	immune	NN
cord-264050-6zpw6itb	3	2	-	-	HYPH
cord-264050-6zpw6itb	3	3	Mediated	mediate	VBN
cord-264050-6zpw6itb	3	4	Damage	damage	NN
cord-264050-6zpw6itb	3	5	Completes	complete	VBZ
cord-264050-6zpw6itb	3	6	the	the	DT
cord-264050-6zpw6itb	3	7	Parabola	parabola	NN
cord-264050-6zpw6itb	3	8	:	:	:
cord-264050-6zpw6itb	4	1	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	4	2	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	4	3	Pathogenesis	Pathogenesis	NNP
cord-264050-6zpw6itb	4	4	Can	Can	MD
cord-264050-6zpw6itb	4	5	Reflect	reflect	VB
cord-264050-6zpw6itb	4	6	the	the	DT
cord-264050-6zpw6itb	4	7	Outcome	outcome	NN
cord-264050-6zpw6itb	4	8	of	of	IN
cord-264050-6zpw6itb	4	9	a	a	DT
cord-264050-6zpw6itb	4	10	Weak	weak	JJ
cord-264050-6zpw6itb	4	11	or	or	CC
cord-264050-6zpw6itb	4	12	Strong	strong	JJ
cord-264050-6zpw6itb	4	13	Immune	Immune	NNP
cord-264050-6zpw6itb	4	14	Response	response	NN
cord-264050-6zpw6itb	4	15	date	date	NN
cord-264050-6zpw6itb	4	16	:	:	:
cord-264050-6zpw6itb	4	17	2017	2017	CD
cord-264050-6zpw6itb	4	18	-	-	HYPH
cord-264050-6zpw6itb	4	19	12	12	CD
cord-264050-6zpw6itb	4	20	-	-	SYM
cord-264050-6zpw6itb	4	21	12	12	CD
cord-264050-6zpw6itb	4	22	journal	journal	NN
cord-264050-6zpw6itb	4	23	:	:	:
cord-264050-6zpw6itb	5	1	mBio	mbio	NN
cord-264050-6zpw6itb	5	2	DOI	doi	NN
cord-264050-6zpw6itb	5	3	:	:	:
cord-264050-6zpw6itb	5	4	10.1128	10.1128	CD
cord-264050-6zpw6itb	5	5	/	/	SYM
cord-264050-6zpw6itb	5	6	mbio.02063	mbio.02063	NNP
cord-264050-6zpw6itb	5	7	-	-	HYPH
cord-264050-6zpw6itb	5	8	17	17	CD
cord-264050-6zpw6itb	5	9	sha	sha	NNP
cord-264050-6zpw6itb	5	10	:	:	:
cord-264050-6zpw6itb	6	1	6aa72847e6c019bbc18254ec5cca30db62200120	6aa72847e6c019bbc18254ec5cca30db62200120	CD
cord-264050-6zpw6itb	6	2	doc_id	doc_id	CD
cord-264050-6zpw6itb	6	3	:	:	:
cord-264050-6zpw6itb	6	4	264050	264050	CD
cord-264050-6zpw6itb	6	5	cord_uid	cord_uid	NNS
cord-264050-6zpw6itb	6	6	:	:	:
cord-264050-6zpw6itb	7	1	6zpw6itb	6zpw6itb	NNP
cord-264050-6zpw6itb	8	1	Cryptococcosis	Cryptococcosis	NNP
cord-264050-6zpw6itb	8	2	occurs	occur	VBZ
cord-264050-6zpw6itb	8	3	most	most	RBS
cord-264050-6zpw6itb	8	4	frequently	frequently	RB
cord-264050-6zpw6itb	8	5	in	in	IN
cord-264050-6zpw6itb	8	6	immunocompromised	immunocompromised	JJ
cord-264050-6zpw6itb	8	7	individuals	individual	NNS
cord-264050-6zpw6itb	8	8	.	.	.
cord-264050-6zpw6itb	9	1	This	this	DT
cord-264050-6zpw6itb	9	2	has	have	VBZ
cord-264050-6zpw6itb	9	3	led	lead	VBN
cord-264050-6zpw6itb	9	4	to	to	IN
cord-264050-6zpw6itb	9	5	the	the	DT
cord-264050-6zpw6itb	9	6	prevailing	prevail	VBG
cord-264050-6zpw6itb	9	7	view	view	NN
cord-264050-6zpw6itb	9	8	that	that	IN
cord-264050-6zpw6itb	9	9	this	this	DT
cord-264050-6zpw6itb	9	10	disease	disease	NN
cord-264050-6zpw6itb	9	11	is	be	VBZ
cord-264050-6zpw6itb	9	12	the	the	DT
cord-264050-6zpw6itb	9	13	result	result	NN
cord-264050-6zpw6itb	9	14	of	of	IN
cord-264050-6zpw6itb	9	15	weak	weak	JJ
cord-264050-6zpw6itb	9	16	immune	immune	JJ
cord-264050-6zpw6itb	9	17	responses	response	NNS
cord-264050-6zpw6itb	9	18	that	that	WDT
cord-264050-6zpw6itb	9	19	can	can	MD
cord-264050-6zpw6itb	9	20	not	not	RB
cord-264050-6zpw6itb	9	21	control	control	VB
cord-264050-6zpw6itb	9	22	the	the	DT
cord-264050-6zpw6itb	9	23	fungus	fungus	NN
cord-264050-6zpw6itb	9	24	.	.	.
cord-264050-6zpw6itb	10	1	However	however	RB
cord-264050-6zpw6itb	10	2	,	,	,
cord-264050-6zpw6itb	10	3	increasingly	increasingly	RB
cord-264050-6zpw6itb	10	4	,	,	,
cord-264050-6zpw6itb	10	5	clinical	clinical	JJ
cord-264050-6zpw6itb	10	6	and	and	CC
cord-264050-6zpw6itb	10	7	experimental	experimental	JJ
cord-264050-6zpw6itb	10	8	studies	study	NNS
cord-264050-6zpw6itb	10	9	have	have	VBP
cord-264050-6zpw6itb	10	10	revealed	reveal	VBN
cord-264050-6zpw6itb	10	11	that	that	IN
cord-264050-6zpw6itb	10	12	the	the	DT
cord-264050-6zpw6itb	10	13	host	host	NN
cord-264050-6zpw6itb	10	14	immune	immune	JJ
cord-264050-6zpw6itb	10	15	response	response	NN
cord-264050-6zpw6itb	10	16	can	can	MD
cord-264050-6zpw6itb	10	17	contribute	contribute	VB
cord-264050-6zpw6itb	10	18	to	to	IN
cord-264050-6zpw6itb	10	19	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	10	20	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	10	21	,	,	,
cord-264050-6zpw6itb	10	22	including	include	VBG
cord-264050-6zpw6itb	10	23	the	the	DT
cord-264050-6zpw6itb	10	24	recent	recent	JJ
cord-264050-6zpw6itb	10	25	study	study	NN
cord-264050-6zpw6itb	10	26	of	of	IN
cord-264050-6zpw6itb	10	27	L.	L.	NNP
cord-264050-6zpw6itb	10	28	M.	M.	NNP
cord-264050-6zpw6itb	10	29	Neal	Neal	NNP
cord-264050-6zpw6itb	10	30	et	et	NNP
cord-264050-6zpw6itb	10	31	al	al	NNP
cord-264050-6zpw6itb	10	32	.	.	.
cord-264050-6zpw6itb	11	1	(	(	-LRB-
cord-264050-6zpw6itb	11	2	mBio	mbio	NN
cord-264050-6zpw6itb	11	3	8	8	CD
cord-264050-6zpw6itb	11	4	:	:	:
cord-264050-6zpw6itb	12	1	e01415	e01415	NNP
cord-264050-6zpw6itb	12	2	-	-	SYM
cord-264050-6zpw6itb	12	3	17	17	CD
cord-264050-6zpw6itb	12	4	,	,	,
cord-264050-6zpw6itb	12	5	2017	2017	CD
cord-264050-6zpw6itb	12	6	,	,	,
cord-264050-6zpw6itb	12	7	https://doi.org/10.1128/mBio.01415-17	https://doi.org/10.1128/mBio.01415-17	NNP
cord-264050-6zpw6itb	12	8	)	)	-RRB-
cord-264050-6zpw6itb	13	1	that	that	DT
cord-264050-6zpw6itb	13	2	reports	report	VBZ
cord-264050-6zpw6itb	13	3	that	that	IN
cord-264050-6zpw6itb	13	4	CD4(+	CD4(+	NNS
cord-264050-6zpw6itb	13	5	)	)	-RRB-
cord-264050-6zpw6itb	14	1	T	t	NN
cord-264050-6zpw6itb	14	2	cells	cell	NNS
cord-264050-6zpw6itb	14	3	mediate	mediate	VBP
cord-264050-6zpw6itb	14	4	tissue	tissue	NN
cord-264050-6zpw6itb	14	5	damage	damage	NN
cord-264050-6zpw6itb	14	6	in	in	IN
cord-264050-6zpw6itb	14	7	experimental	experimental	JJ
cord-264050-6zpw6itb	14	8	murine	murine	NN
cord-264050-6zpw6itb	14	9	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	14	10	.	.	.
cord-264050-6zpw6itb	15	1	This	this	DT
cord-264050-6zpw6itb	15	2	finding	finding	NN
cord-264050-6zpw6itb	15	3	has	have	VBZ
cord-264050-6zpw6itb	15	4	fundamental	fundamental	JJ
cord-264050-6zpw6itb	15	5	implications	implication	NNS
cord-264050-6zpw6itb	15	6	for	for	IN
cord-264050-6zpw6itb	15	7	our	-PRON-	PRP$
cord-264050-6zpw6itb	15	8	understanding	understanding	NN
cord-264050-6zpw6itb	15	9	of	of	IN
cord-264050-6zpw6itb	15	10	the	the	DT
cord-264050-6zpw6itb	15	11	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	15	12	of	of	IN
cord-264050-6zpw6itb	15	13	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	15	14	disease	disease	NN
cord-264050-6zpw6itb	15	15	;	;	:
cord-264050-6zpw6itb	15	16	it	-PRON-	PRP
cord-264050-6zpw6itb	15	17	helps	help	VBZ
cord-264050-6zpw6itb	15	18	explain	explain	VB
cord-264050-6zpw6itb	15	19	why	why	WRB
cord-264050-6zpw6itb	15	20	immunotherapy	immunotherapy	NN
cord-264050-6zpw6itb	15	21	has	have	VBZ
cord-264050-6zpw6itb	15	22	been	be	VBN
cord-264050-6zpw6itb	15	23	largely	largely	RB
cord-264050-6zpw6itb	15	24	unsuccessful	unsuccessful	JJ
cord-264050-6zpw6itb	15	25	in	in	IN
cord-264050-6zpw6itb	15	26	treatment	treatment	NN
cord-264050-6zpw6itb	15	27	and	and	CC
cord-264050-6zpw6itb	15	28	provides	provide	VBZ
cord-264050-6zpw6itb	15	29	insight	insight	NN
cord-264050-6zpw6itb	15	30	into	into	IN
cord-264050-6zpw6itb	15	31	the	the	DT
cord-264050-6zpw6itb	15	32	paradoxical	paradoxical	JJ
cord-264050-6zpw6itb	15	33	observation	observation	NN
cord-264050-6zpw6itb	15	34	that	that	IN
cord-264050-6zpw6itb	15	35	HIV	HIV	NNP
cord-264050-6zpw6itb	15	36	-	-	HYPH
cord-264050-6zpw6itb	15	37	associated	associate	VBN
cord-264050-6zpw6itb	15	38	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	15	39	may	may	MD
cord-264050-6zpw6itb	15	40	have	have	VB
cord-264050-6zpw6itb	15	41	a	a	DT
cord-264050-6zpw6itb	15	42	better	well	JJR
cord-264050-6zpw6itb	15	43	prognosis	prognosis	NN
cord-264050-6zpw6itb	15	44	than	than	IN
cord-264050-6zpw6itb	15	45	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	15	46	in	in	IN
cord-264050-6zpw6itb	15	47	those	those	DT
cord-264050-6zpw6itb	15	48	with	with	IN
cord-264050-6zpw6itb	15	49	no	no	DT
cord-264050-6zpw6itb	15	50	known	know	VBN
cord-264050-6zpw6itb	15	51	immune	immune	JJ
cord-264050-6zpw6itb	15	52	impairment	impairment	NN
cord-264050-6zpw6itb	15	53	.	.	.
cord-264050-6zpw6itb	16	1	The	the	DT
cord-264050-6zpw6itb	16	2	demonstration	demonstration	NN
cord-264050-6zpw6itb	16	3	that	that	WDT
cord-264050-6zpw6itb	16	4	host	host	NN
cord-264050-6zpw6itb	16	5	-	-	HYPH
cord-264050-6zpw6itb	16	6	mediated	mediate	VBN
cord-264050-6zpw6itb	16	7	damage	damage	NN
cord-264050-6zpw6itb	16	8	can	can	MD
cord-264050-6zpw6itb	16	9	drive	drive	VB
cord-264050-6zpw6itb	16	10	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	16	11	disease	disease	NN
cord-264050-6zpw6itb	16	12	provides	provide	VBZ
cord-264050-6zpw6itb	16	13	proof	proof	NN
cord-264050-6zpw6itb	16	14	of	of	IN
cord-264050-6zpw6itb	16	15	concept	concept	NN
cord-264050-6zpw6itb	16	16	that	that	IN
cord-264050-6zpw6itb	16	17	the	the	DT
cord-264050-6zpw6itb	16	18	parabola	parabola	NN
cord-264050-6zpw6itb	16	19	put	put	VBD
cord-264050-6zpw6itb	16	20	forth	forth	RP
cord-264050-6zpw6itb	16	21	in	in	IN
cord-264050-6zpw6itb	16	22	the	the	DT
cord-264050-6zpw6itb	16	23	damage	damage	NN
cord-264050-6zpw6itb	16	24	-	-	HYPH
cord-264050-6zpw6itb	16	25	response	response	NN
cord-264050-6zpw6itb	16	26	framework	framework	NN
cord-264050-6zpw6itb	16	27	has	have	VBZ
cord-264050-6zpw6itb	16	28	the	the	DT
cord-264050-6zpw6itb	16	29	flexibility	flexibility	NN
cord-264050-6zpw6itb	16	30	to	to	TO
cord-264050-6zpw6itb	16	31	depict	depict	VB
cord-264050-6zpw6itb	16	32	complex	complex	JJ
cord-264050-6zpw6itb	16	33	and	and	CC
cord-264050-6zpw6itb	16	34	changing	change	VBG
cord-264050-6zpw6itb	16	35	outcomes	outcome	NNS
cord-264050-6zpw6itb	16	36	of	of	IN
cord-264050-6zpw6itb	16	37	host	host	NN
cord-264050-6zpw6itb	16	38	-	-	HYPH
cord-264050-6zpw6itb	16	39	microbe	microbe	NN
cord-264050-6zpw6itb	16	40	interaction	interaction	NN
cord-264050-6zpw6itb	16	41	.	.	.
cord-264050-6zpw6itb	17	1	C	C	NNP
cord-264050-6zpw6itb	17	2	ryptococcosis	ryptococcosis	NN
cord-264050-6zpw6itb	17	3	is	be	VBZ
cord-264050-6zpw6itb	17	4	usually	usually	RB
cord-264050-6zpw6itb	17	5	observed	observe	VBN
cord-264050-6zpw6itb	17	6	in	in	IN
cord-264050-6zpw6itb	17	7	hosts	host	NNS
cord-264050-6zpw6itb	17	8	with	with	IN
cord-264050-6zpw6itb	17	9	impaired	impaired	JJ
cord-264050-6zpw6itb	17	10	immunity	immunity	NN
cord-264050-6zpw6itb	17	11	.	.	.
cord-264050-6zpw6itb	18	1	Consequently	consequently	RB
cord-264050-6zpw6itb	18	2	,	,	,
cord-264050-6zpw6itb	18	3	the	the	DT
cord-264050-6zpw6itb	18	4	agent	agent	NN
cord-264050-6zpw6itb	18	5	causing	cause	VBG
cord-264050-6zpw6itb	18	6	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	18	7	,	,	,
cord-264050-6zpw6itb	18	8	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	18	9	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	18	10	,	,	,
cord-264050-6zpw6itb	18	11	is	be	VBZ
cord-264050-6zpw6itb	18	12	often	often	RB
cord-264050-6zpw6itb	18	13	considered	consider	VBN
cord-264050-6zpw6itb	18	14	pathogenic	pathogenic	JJ
cord-264050-6zpw6itb	18	15	only	only	RB
cord-264050-6zpw6itb	18	16	when	when	WRB
cord-264050-6zpw6itb	18	17	the	the	DT
cord-264050-6zpw6itb	18	18	immune	immune	JJ
cord-264050-6zpw6itb	18	19	system	system	NN
cord-264050-6zpw6itb	18	20	is	be	VBZ
cord-264050-6zpw6itb	18	21	unable	unable	JJ
cord-264050-6zpw6itb	18	22	to	to	TO
cord-264050-6zpw6itb	18	23	control	control	VB
cord-264050-6zpw6itb	18	24	its	-PRON-	PRP$
cord-264050-6zpw6itb	18	25	growth	growth	NN
cord-264050-6zpw6itb	18	26	.	.	.
cord-264050-6zpw6itb	19	1	This	this	DT
cord-264050-6zpw6itb	19	2	has	have	VBZ
cord-264050-6zpw6itb	19	3	led	lead	VBN
cord-264050-6zpw6itb	19	4	to	to	IN
cord-264050-6zpw6itb	19	5	its	-PRON-	PRP$
cord-264050-6zpw6itb	19	6	characterization	characterization	NN
cord-264050-6zpw6itb	19	7	as	as	IN
cord-264050-6zpw6itb	19	8	an	an	DT
cord-264050-6zpw6itb	19	9	"	"	``
cord-264050-6zpw6itb	19	10	opportunistic	opportunistic	JJ
cord-264050-6zpw6itb	19	11	pathogen	pathogen	NN
cord-264050-6zpw6itb	19	12	"	"	''
cord-264050-6zpw6itb	19	13	(	(	-LRB-
cord-264050-6zpw6itb	19	14	1	1	CD
cord-264050-6zpw6itb	19	15	)	)	-RRB-
cord-264050-6zpw6itb	19	16	.	.	.
cord-264050-6zpw6itb	20	1	In	in	IN
cord-264050-6zpw6itb	20	2	their	-PRON-	PRP$
cord-264050-6zpw6itb	20	3	article	article	NN
cord-264050-6zpw6itb	20	4	in	in	IN
cord-264050-6zpw6itb	20	5	mBio	mBio	NNP
cord-264050-6zpw6itb	20	6	,	,	,
cord-264050-6zpw6itb	20	7	L.	L.	NNP
cord-264050-6zpw6itb	20	8	M.	M.	NNP
cord-264050-6zpw6itb	20	9	Neal	Neal	NNP
cord-264050-6zpw6itb	20	10	et	et	NNP
cord-264050-6zpw6itb	20	11	al	al	NNP
cord-264050-6zpw6itb	20	12	.	.	.
cord-264050-6zpw6itb	21	1	(	(	-LRB-
cord-264050-6zpw6itb	21	2	2	2	LS
cord-264050-6zpw6itb	21	3	)	)	-RRB-
cord-264050-6zpw6itb	21	4	report	report	VBP
cord-264050-6zpw6itb	21	5	that	that	IN
cord-264050-6zpw6itb	21	6	the	the	DT
cord-264050-6zpw6itb	21	7	CD4	CD4	NNP
cord-264050-6zpw6itb	21	8	ϩ	ϩ	NN
cord-264050-6zpw6itb	21	9	T	T	NNP
cord-264050-6zpw6itb	21	10	cell	cell	NN
cord-264050-6zpw6itb	21	11	-	-	HYPH
cord-264050-6zpw6itb	21	12	mediated	mediate	VBN
cord-264050-6zpw6itb	21	13	response	response	NN
cord-264050-6zpw6itb	21	14	to	to	IN
cord-264050-6zpw6itb	21	15	C.	C.	NNP
cord-264050-6zpw6itb	21	16	neoformans	neoformans	NNP
cord-264050-6zpw6itb	21	17	is	be	VBZ
cord-264050-6zpw6itb	21	18	a	a	DT
cord-264050-6zpw6itb	21	19	major	major	JJ
cord-264050-6zpw6itb	21	20	contributor	contributor	NN
cord-264050-6zpw6itb	21	21	to	to	IN
cord-264050-6zpw6itb	21	22	tissue	tissue	NN
cord-264050-6zpw6itb	21	23	damage	damage	NN
cord-264050-6zpw6itb	21	24	in	in	IN
cord-264050-6zpw6itb	21	25	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	21	26	meningitis	meningitis	NN
cord-264050-6zpw6itb	21	27	in	in	IN
cord-264050-6zpw6itb	21	28	mice	mouse	NNS
cord-264050-6zpw6itb	21	29	even	even	RB
cord-264050-6zpw6itb	21	30	though	though	IN
cord-264050-6zpw6itb	21	31	it	-PRON-	PRP
cord-264050-6zpw6itb	21	32	also	also	RB
cord-264050-6zpw6itb	21	33	mediates	mediate	VBZ
cord-264050-6zpw6itb	21	34	fungal	fungal	JJ
cord-264050-6zpw6itb	21	35	clearance	clearance	NN
cord-264050-6zpw6itb	21	36	.	.	.
cord-264050-6zpw6itb	22	1	This	this	DT
cord-264050-6zpw6itb	22	2	observation	observation	NN
cord-264050-6zpw6itb	22	3	adds	add	VBZ
cord-264050-6zpw6itb	22	4	to	to	IN
cord-264050-6zpw6itb	22	5	increasing	increase	VBG
cord-264050-6zpw6itb	22	6	evidence	evidence	NN
cord-264050-6zpw6itb	22	7	that	that	IN
cord-264050-6zpw6itb	22	8	the	the	DT
cord-264050-6zpw6itb	22	9	host	host	NN
cord-264050-6zpw6itb	22	10	response	response	NN
cord-264050-6zpw6itb	22	11	can	can	MD
cord-264050-6zpw6itb	22	12	drive	drive	VB
cord-264050-6zpw6itb	22	13	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	22	14	disease	disease	NN
cord-264050-6zpw6itb	22	15	and	and	CC
cord-264050-6zpw6itb	22	16	highlights	highlight	VBZ
cord-264050-6zpw6itb	22	17	the	the	DT
cord-264050-6zpw6itb	22	18	ability	ability	NN
cord-264050-6zpw6itb	22	19	of	of	IN
cord-264050-6zpw6itb	22	20	the	the	DT
cord-264050-6zpw6itb	22	21	damageresponse	damageresponse	NNP
cord-264050-6zpw6itb	22	22	framework	framework	NN
cord-264050-6zpw6itb	22	23	(	(	-LRB-
cord-264050-6zpw6itb	22	24	DRF	DRF	NNP
cord-264050-6zpw6itb	22	25	)	)	-RRB-
cord-264050-6zpw6itb	22	26	to	to	TO
cord-264050-6zpw6itb	22	27	guide	guide	VB
cord-264050-6zpw6itb	22	28	our	-PRON-	PRP$
cord-264050-6zpw6itb	22	29	understanding	understanding	NN
cord-264050-6zpw6itb	22	30	of	of	IN
cord-264050-6zpw6itb	22	31	microbial	microbial	JJ
cord-264050-6zpw6itb	22	32	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	22	33	.	.	.
cord-264050-6zpw6itb	23	1	The	the	DT
cord-264050-6zpw6itb	23	2	DRF	DRF	NNP
cord-264050-6zpw6itb	23	3	was	be	VBD
cord-264050-6zpw6itb	23	4	first	first	RB
cord-264050-6zpw6itb	23	5	put	put	VBN
cord-264050-6zpw6itb	23	6	forth	forth	RB
cord-264050-6zpw6itb	23	7	in	in	IN
cord-264050-6zpw6itb	23	8	1999	1999	CD
cord-264050-6zpw6itb	23	9	(	(	-LRB-
cord-264050-6zpw6itb	23	10	3	3	CD
cord-264050-6zpw6itb	23	11	)	)	-RRB-
cord-264050-6zpw6itb	23	12	to	to	TO
cord-264050-6zpw6itb	23	13	provide	provide	VB
cord-264050-6zpw6itb	23	14	a	a	DT
cord-264050-6zpw6itb	23	15	theory	theory	NN
cord-264050-6zpw6itb	23	16	of	of	IN
cord-264050-6zpw6itb	23	17	microbial	microbial	JJ
cord-264050-6zpw6itb	23	18	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	23	19	that	that	WDT
cord-264050-6zpw6itb	23	20	could	could	MD
cord-264050-6zpw6itb	23	21	incorporate	incorporate	VB
cord-264050-6zpw6itb	23	22	the	the	DT
cord-264050-6zpw6itb	23	23	contributions	contribution	NNS
cord-264050-6zpw6itb	23	24	of	of	IN
cord-264050-6zpw6itb	23	25	both	both	DT
cord-264050-6zpw6itb	23	26	host	host	NN
cord-264050-6zpw6itb	23	27	and	and	CC
cord-264050-6zpw6itb	23	28	microbe	microbe	NN
cord-264050-6zpw6itb	23	29	to	to	TO
cord-264050-6zpw6itb	23	30	host	host	VB
cord-264050-6zpw6itb	23	31	damage	damage	NN
cord-264050-6zpw6itb	23	32	that	that	WDT
cord-264050-6zpw6itb	23	33	stems	stem	VBZ
cord-264050-6zpw6itb	23	34	from	from	IN
cord-264050-6zpw6itb	23	35	host	host	NN
cord-264050-6zpw6itb	23	36	-	-	HYPH
cord-264050-6zpw6itb	23	37	microbe	microbe	NN
cord-264050-6zpw6itb	23	38	interaction	interaction	NN
cord-264050-6zpw6itb	23	39	.	.	.
cord-264050-6zpw6itb	24	1	Prior	prior	RB
cord-264050-6zpw6itb	24	2	to	to	IN
cord-264050-6zpw6itb	24	3	the	the	DT
cord-264050-6zpw6itb	24	4	DRF	drf	NN
cord-264050-6zpw6itb	24	5	,	,	,
cord-264050-6zpw6itb	24	6	microbial	microbial	JJ
cord-264050-6zpw6itb	24	7	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	24	8	was	be	VBD
cord-264050-6zpw6itb	24	9	largely	largely	RB
cord-264050-6zpw6itb	24	10	viewed	view	VBN
cord-264050-6zpw6itb	24	11	as	as	IN
cord-264050-6zpw6itb	24	12	a	a	DT
cord-264050-6zpw6itb	24	13	singular	singular	JJ
cord-264050-6zpw6itb	24	14	outcome	outcome	NN
cord-264050-6zpw6itb	24	15	of	of	IN
cord-264050-6zpw6itb	24	16	either	either	DT
cord-264050-6zpw6itb	24	17	microbial	microbial	JJ
cord-264050-6zpw6itb	24	18	factors	factor	NNS
cord-264050-6zpw6itb	24	19	or	or	CC
cord-264050-6zpw6itb	24	20	host	host	NN
cord-264050-6zpw6itb	24	21	factors	factor	NNS
cord-264050-6zpw6itb	24	22	.	.	.
cord-264050-6zpw6itb	25	1	While	while	IN
cord-264050-6zpw6itb	25	2	such	such	JJ
cord-264050-6zpw6itb	25	3	microbe	microbe	NN
cord-264050-6zpw6itb	25	4	-	-	:
cord-264050-6zpw6itb	25	5	or	or	CC
cord-264050-6zpw6itb	25	6	host	host	NN
cord-264050-6zpw6itb	25	7	-	-	HYPH
cord-264050-6zpw6itb	25	8	centered	center	VBN
cord-264050-6zpw6itb	25	9	views	view	NNS
cord-264050-6zpw6itb	25	10	were	be	VBD
cord-264050-6zpw6itb	25	11	able	able	JJ
cord-264050-6zpw6itb	25	12	to	to	TO
cord-264050-6zpw6itb	25	13	explain	explain	VB
cord-264050-6zpw6itb	25	14	the	the	DT
cord-264050-6zpw6itb	25	15	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	25	16	of	of	IN
cord-264050-6zpw6itb	25	17	certain	certain	JJ
cord-264050-6zpw6itb	25	18	infectious	infectious	JJ
cord-264050-6zpw6itb	25	19	diseases	disease	NNS
cord-264050-6zpw6itb	25	20	,	,	,
cord-264050-6zpw6itb	25	21	they	-PRON-	PRP
cord-264050-6zpw6itb	25	22	could	could	MD
cord-264050-6zpw6itb	25	23	not	not	RB
cord-264050-6zpw6itb	25	24	explain	explain	VB
cord-264050-6zpw6itb	25	25	others	other	NNS
cord-264050-6zpw6itb	25	26	,	,	,
cord-264050-6zpw6itb	25	27	especially	especially	RB
cord-264050-6zpw6itb	25	28	those	those	DT
cord-264050-6zpw6itb	25	29	caused	cause	VBN
cord-264050-6zpw6itb	25	30	by	by	IN
cord-264050-6zpw6itb	25	31	microbes	microbe	NNS
cord-264050-6zpw6itb	25	32	only	only	RB
cord-264050-6zpw6itb	25	33	rarely	rarely	RB
cord-264050-6zpw6itb	25	34	associated	associate	VBN
cord-264050-6zpw6itb	25	35	with	with	IN
cord-264050-6zpw6itb	25	36	disease	disease	NN
cord-264050-6zpw6itb	25	37	.	.	.
cord-264050-6zpw6itb	26	1	This	this	DT
cord-264050-6zpw6itb	26	2	shortcoming	shortcoming	NN
cord-264050-6zpw6itb	26	3	became	become	VBD
cord-264050-6zpw6itb	26	4	glaring	glaring	JJ
cord-264050-6zpw6itb	26	5	in	in	IN
cord-264050-6zpw6itb	26	6	the	the	DT
cord-264050-6zpw6itb	26	7	late	late	JJ
cord-264050-6zpw6itb	26	8	1970s	1970	NNS
cord-264050-6zpw6itb	26	9	and	and	CC
cord-264050-6zpw6itb	26	10	early	early	JJ
cord-264050-6zpw6itb	26	11	1980s	1980s	CD
cord-264050-6zpw6itb	26	12	as	as	IN
cord-264050-6zpw6itb	26	13	the	the	DT
cord-264050-6zpw6itb	26	14	HIV	HIV	NNP
cord-264050-6zpw6itb	26	15	/	/	SYM
cord-264050-6zpw6itb	26	16	AIDS	AIDS	NNP
cord-264050-6zpw6itb	26	17	pandemic	pandemic	NN
cord-264050-6zpw6itb	26	18	led	lead	VBD
cord-264050-6zpw6itb	26	19	to	to	IN
cord-264050-6zpw6itb	26	20	the	the	DT
cord-264050-6zpw6itb	26	21	emergence	emergence	NN
cord-264050-6zpw6itb	26	22	of	of	IN
cord-264050-6zpw6itb	26	23	previously	previously	RB
cord-264050-6zpw6itb	26	24	rare	rare	JJ
cord-264050-6zpw6itb	26	25	and	and	CC
cord-264050-6zpw6itb	26	26	unusual	unusual	JJ
cord-264050-6zpw6itb	26	27	diseases	disease	NNS
cord-264050-6zpw6itb	26	28	,	,	,
cord-264050-6zpw6itb	26	29	including	include	VBG
cord-264050-6zpw6itb	26	30	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	26	31	(	(	-LRB-
cord-264050-6zpw6itb	26	32	4	4	CD
cord-264050-6zpw6itb	26	33	)	)	-RRB-
cord-264050-6zpw6itb	26	34	.	.	.
cord-264050-6zpw6itb	27	1	In	in	IN
cord-264050-6zpw6itb	27	2	the	the	DT
cord-264050-6zpw6itb	27	3	original	original	JJ
cord-264050-6zpw6itb	27	4	formulation	formulation	NN
cord-264050-6zpw6itb	27	5	of	of	IN
cord-264050-6zpw6itb	27	6	the	the	DT
cord-264050-6zpw6itb	27	7	DRF	DRF	NNP
cord-264050-6zpw6itb	27	8	,	,	,
cord-264050-6zpw6itb	27	9	the	the	DT
cord-264050-6zpw6itb	27	10	outcome	outcome	NN
cord-264050-6zpw6itb	27	11	of	of	IN
cord-264050-6zpw6itb	27	12	host	host	NN
cord-264050-6zpw6itb	27	13	-	-	HYPH
cord-264050-6zpw6itb	27	14	microbe	microbe	NN
cord-264050-6zpw6itb	27	15	interaction	interaction	NN
cord-264050-6zpw6itb	27	16	with	with	IN
cord-264050-6zpw6itb	27	17	different	different	JJ
cord-264050-6zpw6itb	27	18	microbes	microbe	NNS
cord-264050-6zpw6itb	27	19	was	be	VBD
cord-264050-6zpw6itb	27	20	depicted	depict	VBN
cord-264050-6zpw6itb	27	21	by	by	IN
cord-264050-6zpw6itb	27	22	six	six	CD
cord-264050-6zpw6itb	27	23	curves	curve	NNS
cord-264050-6zpw6itb	27	24	that	that	WDT
cord-264050-6zpw6itb	27	25	plotted	plot	VBD
cord-264050-6zpw6itb	27	26	host	host	NN
cord-264050-6zpw6itb	27	27	damage	damage	NN
cord-264050-6zpw6itb	27	28	as	as	IN
cord-264050-6zpw6itb	27	29	a	a	DT
cord-264050-6zpw6itb	27	30	function	function	NN
cord-264050-6zpw6itb	27	31	of	of	IN
cord-264050-6zpw6itb	27	32	the	the	DT
cord-264050-6zpw6itb	27	33	strength	strength	NN
cord-264050-6zpw6itb	27	34	of	of	IN
cord-264050-6zpw6itb	27	35	the	the	DT
cord-264050-6zpw6itb	27	36	immune	immune	JJ
cord-264050-6zpw6itb	27	37	response	response	NN
cord-264050-6zpw6itb	27	38	.	.	.
cord-264050-6zpw6itb	28	1	These	these	DT
cord-264050-6zpw6itb	28	2	curves	curve	NNS
cord-264050-6zpw6itb	28	3	,	,	,
cord-264050-6zpw6itb	28	4	referred	refer	VBD
cord-264050-6zpw6itb	28	5	to	to	IN
cord-264050-6zpw6itb	28	6	as	as	IN
cord-264050-6zpw6itb	28	7	pathogen	pathogen	NN
cord-264050-6zpw6itb	28	8	classes	class	NNS
cord-264050-6zpw6itb	28	9	,	,	,
cord-264050-6zpw6itb	28	10	were	be	VBD
cord-264050-6zpw6itb	28	11	based	base	VBN
cord-264050-6zpw6itb	28	12	on	on	IN
cord-264050-6zpw6itb	28	13	what	what	WP
cord-264050-6zpw6itb	28	14	was	be	VBD
cord-264050-6zpw6itb	28	15	known	know	VBN
cord-264050-6zpw6itb	28	16	at	at	IN
cord-264050-6zpw6itb	28	17	the	the	DT
cord-264050-6zpw6itb	28	18	time	time	NN
cord-264050-6zpw6itb	28	19	about	about	IN
cord-264050-6zpw6itb	28	20	the	the	DT
cord-264050-6zpw6itb	28	21	outcome	outcome	NN
cord-264050-6zpw6itb	28	22	of	of	IN
cord-264050-6zpw6itb	28	23	infection	infection	NN
cord-264050-6zpw6itb	28	24	with	with	IN
cord-264050-6zpw6itb	28	25	given	give	VBN
cord-264050-6zpw6itb	28	26	microbes	microbe	NNS
cord-264050-6zpw6itb	28	27	.	.	.
cord-264050-6zpw6itb	29	1	The	the	DT
cord-264050-6zpw6itb	29	2	rationale	rationale	NN
cord-264050-6zpw6itb	29	3	for	for	IN
cord-264050-6zpw6itb	29	4	the	the	DT
cord-264050-6zpw6itb	29	5	pathogen	pathogen	NN
cord-264050-6zpw6itb	29	6	classes	class	NNS
cord-264050-6zpw6itb	29	7	was	be	VBD
cord-264050-6zpw6itb	29	8	underpinned	underpin	VBN
cord-264050-6zpw6itb	29	9	by	by	IN
cord-264050-6zpw6itb	29	10	the	the	DT
cord-264050-6zpw6itb	29	11	tenet	tenet	NN
cord-264050-6zpw6itb	29	12	that	that	IN
cord-264050-6zpw6itb	29	13	host	host	NN
cord-264050-6zpw6itb	29	14	damage	damage	NN
cord-264050-6zpw6itb	29	15	can	can	MD
cord-264050-6zpw6itb	29	16	stem	stem	VB
cord-264050-6zpw6itb	29	17	from	from	IN
cord-264050-6zpw6itb	29	18	microbial	microbial	JJ
cord-264050-6zpw6itb	29	19	factors	factor	NNS
cord-264050-6zpw6itb	29	20	,	,	,
cord-264050-6zpw6itb	29	21	host	host	NN
cord-264050-6zpw6itb	29	22	factors	factor	NNS
cord-264050-6zpw6itb	29	23	,	,	,
cord-264050-6zpw6itb	29	24	or	or	CC
cord-264050-6zpw6itb	29	25	both	both	DT
cord-264050-6zpw6itb	29	26	.	.	.
cord-264050-6zpw6itb	30	1	Central	central	JJ
cord-264050-6zpw6itb	30	2	to	to	IN
cord-264050-6zpw6itb	30	3	this	this	DT
cord-264050-6zpw6itb	30	4	tenet	tenet	NN
cord-264050-6zpw6itb	30	5	was	be	VBD
cord-264050-6zpw6itb	30	6	the	the	DT
cord-264050-6zpw6itb	30	7	idea	idea	NN
cord-264050-6zpw6itb	30	8	that	that	IN
cord-264050-6zpw6itb	30	9	host	host	NN
cord-264050-6zpw6itb	30	10	damage	damage	NN
cord-264050-6zpw6itb	30	11	stemming	stem	VBG
cord-264050-6zpw6itb	30	12	from	from	IN
cord-264050-6zpw6itb	30	13	the	the	DT
cord-264050-6zpw6itb	30	14	immune	immune	JJ
cord-264050-6zpw6itb	30	15	response	response	NN
cord-264050-6zpw6itb	30	16	to	to	IN
cord-264050-6zpw6itb	30	17	a	a	DT
cord-264050-6zpw6itb	30	18	microbe	microbe	NN
cord-264050-6zpw6itb	30	19	can	can	MD
cord-264050-6zpw6itb	30	20	drive	drive	VB
cord-264050-6zpw6itb	30	21	disease	disease	NN
cord-264050-6zpw6itb	30	22	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	30	23	.	.	.
cord-264050-6zpw6itb	31	1	At	at	IN
cord-264050-6zpw6itb	31	2	the	the	DT
cord-264050-6zpw6itb	31	3	time	time	NN
cord-264050-6zpw6itb	31	4	the	the	DT
cord-264050-6zpw6itb	31	5	DRF	DRF	NNP
cord-264050-6zpw6itb	31	6	was	be	VBD
cord-264050-6zpw6itb	31	7	proposed	propose	VBN
cord-264050-6zpw6itb	31	8	,	,	,
cord-264050-6zpw6itb	31	9	the	the	DT
cord-264050-6zpw6itb	31	10	host	host	NN
cord-264050-6zpw6itb	31	11	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	31	12	response	response	NN
cord-264050-6zpw6itb	31	13	was	be	VBD
cord-264050-6zpw6itb	31	14	not	not	RB
cord-264050-6zpw6itb	31	15	generally	generally	RB
cord-264050-6zpw6itb	31	16	viewed	view	VBN
cord-264050-6zpw6itb	31	17	as	as	IN
cord-264050-6zpw6itb	31	18	a	a	DT
cord-264050-6zpw6itb	31	19	causal	causal	JJ
cord-264050-6zpw6itb	31	20	factor	factor	NN
cord-264050-6zpw6itb	31	21	in	in	IN
cord-264050-6zpw6itb	31	22	the	the	DT
cord-264050-6zpw6itb	31	23	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	31	24	of	of	IN
cord-264050-6zpw6itb	31	25	infectious	infectious	JJ
cord-264050-6zpw6itb	31	26	diseases	disease	NNS
cord-264050-6zpw6itb	31	27	.	.	.
cord-264050-6zpw6itb	32	1	However	however	RB
cord-264050-6zpw6itb	32	2	,	,	,
cord-264050-6zpw6itb	32	3	this	this	DT
cord-264050-6zpw6itb	32	4	has	have	VBZ
cord-264050-6zpw6itb	32	5	changed	change	VBN
cord-264050-6zpw6itb	32	6	.	.	.
cord-264050-6zpw6itb	33	1	The	the	DT
cord-264050-6zpw6itb	33	2	occurrence	occurrence	NN
cord-264050-6zpw6itb	33	3	of	of	IN
cord-264050-6zpw6itb	33	4	severe	severe	JJ
cord-264050-6zpw6itb	33	5	acute	acute	JJ
cord-264050-6zpw6itb	33	6	respiratory	respiratory	JJ
cord-264050-6zpw6itb	33	7	syndrome	syndrome	NN
cord-264050-6zpw6itb	33	8	(	(	-LRB-
cord-264050-6zpw6itb	33	9	SARS	SARS	NNP
cord-264050-6zpw6itb	33	10	)	)	-RRB-
cord-264050-6zpw6itb	33	11	in	in	IN
cord-264050-6zpw6itb	33	12	young	young	JJ
cord-264050-6zpw6itb	33	13	,	,	,
cord-264050-6zpw6itb	33	14	previously	previously	RB
cord-264050-6zpw6itb	33	15	well	well	RB
cord-264050-6zpw6itb	33	16	persons	person	NNS
cord-264050-6zpw6itb	33	17	who	who	WP
cord-264050-6zpw6itb	33	18	presented	present	VBD
cord-264050-6zpw6itb	33	19	with	with	IN
cord-264050-6zpw6itb	33	20	excessive	excessive	JJ
cord-264050-6zpw6itb	33	21	pulmonary	pulmonary	JJ
cord-264050-6zpw6itb	33	22	inflammation	inflammation	NN
cord-264050-6zpw6itb	33	23	(	(	-LRB-
cord-264050-6zpw6itb	33	24	5	5	CD
cord-264050-6zpw6itb	33	25	)	)	-RRB-
cord-264050-6zpw6itb	33	26	,	,	,
cord-264050-6zpw6itb	33	27	reminiscent	reminiscent	JJ
cord-264050-6zpw6itb	33	28	of	of	IN
cord-264050-6zpw6itb	33	29	influenza	influenza	NN
cord-264050-6zpw6itb	33	30	epidemics	epidemic	NNS
cord-264050-6zpw6itb	33	31	that	that	WDT
cord-264050-6zpw6itb	33	32	struck	strike	VBD
cord-264050-6zpw6itb	33	33	young	young	JJ
cord-264050-6zpw6itb	33	34	,	,	,
cord-264050-6zpw6itb	33	35	robust	robust	JJ
cord-264050-6zpw6itb	33	36	persons	person	NNS
cord-264050-6zpw6itb	33	37	(	(	-LRB-
cord-264050-6zpw6itb	33	38	6	6	CD
cord-264050-6zpw6itb	33	39	)	)	-RRB-
cord-264050-6zpw6itb	33	40	,	,	,
cord-264050-6zpw6itb	33	41	highlighted	highlight	VBD
cord-264050-6zpw6itb	33	42	the	the	DT
cord-264050-6zpw6itb	33	43	role	role	NN
cord-264050-6zpw6itb	33	44	that	that	IN
cord-264050-6zpw6itb	33	45	host	host	NN
cord-264050-6zpw6itb	33	46	-	-	HYPH
cord-264050-6zpw6itb	33	47	mediated	mediate	VBN
cord-264050-6zpw6itb	33	48	damage	damage	NN
cord-264050-6zpw6itb	33	49	can	can	MD
cord-264050-6zpw6itb	33	50	play	play	VB
cord-264050-6zpw6itb	33	51	in	in	IN
cord-264050-6zpw6itb	33	52	viral	viral	JJ
cord-264050-6zpw6itb	33	53	disease	disease	NN
cord-264050-6zpw6itb	33	54	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	33	55	.	.	.
cord-264050-6zpw6itb	34	1	The	the	DT
cord-264050-6zpw6itb	34	2	ability	ability	NN
cord-264050-6zpw6itb	34	3	of	of	IN
cord-264050-6zpw6itb	34	4	the	the	DT
cord-264050-6zpw6itb	34	5	DRF	DRF	NNP
cord-264050-6zpw6itb	34	6	to	to	TO
cord-264050-6zpw6itb	34	7	account	account	VB
cord-264050-6zpw6itb	34	8	for	for	IN
cord-264050-6zpw6itb	34	9	host	host	NN
cord-264050-6zpw6itb	34	10	damage	damage	NN
cord-264050-6zpw6itb	34	11	due	due	IN
cord-264050-6zpw6itb	34	12	to	to	IN
cord-264050-6zpw6itb	34	13	inflammation	inflammation	NN
cord-264050-6zpw6itb	34	14	stemming	stem	VBG
cord-264050-6zpw6itb	34	15	from	from	IN
cord-264050-6zpw6itb	34	16	the	the	DT
cord-264050-6zpw6itb	34	17	immune	immune	JJ
cord-264050-6zpw6itb	34	18	response	response	NN
cord-264050-6zpw6itb	34	19	to	to	IN
cord-264050-6zpw6itb	34	20	certain	certain	JJ
cord-264050-6zpw6itb	34	21	microbes	microbe	NNS
cord-264050-6zpw6itb	34	22	(	(	-LRB-
cord-264050-6zpw6itb	34	23	3	3	CD
cord-264050-6zpw6itb	34	24	)	)	-RRB-
cord-264050-6zpw6itb	34	25	highlighted	highlight	VBD
cord-264050-6zpw6itb	34	26	its	-PRON-	PRP$
cord-264050-6zpw6itb	34	27	flexibility	flexibility	NN
cord-264050-6zpw6itb	34	28	and	and	CC
cord-264050-6zpw6itb	34	29	capacity	capacity	NN
cord-264050-6zpw6itb	34	30	to	to	TO
cord-264050-6zpw6itb	34	31	incorporate	incorporate	VB
cord-264050-6zpw6itb	34	32	new	new	JJ
cord-264050-6zpw6itb	34	33	diseases	disease	NNS
cord-264050-6zpw6itb	34	34	and	and	CC
cord-264050-6zpw6itb	34	35	information	information	NN
cord-264050-6zpw6itb	34	36	.	.	.
cord-264050-6zpw6itb	35	1	Despite	despite	IN
cord-264050-6zpw6itb	35	2	the	the	DT
cord-264050-6zpw6itb	35	3	ability	ability	NN
cord-264050-6zpw6itb	35	4	of	of	IN
cord-264050-6zpw6itb	35	5	the	the	DT
cord-264050-6zpw6itb	35	6	DRF	DRF	NNP
cord-264050-6zpw6itb	35	7	to	to	TO
cord-264050-6zpw6itb	35	8	classify	classify	VB
cord-264050-6zpw6itb	35	9	most	most	JJS
cord-264050-6zpw6itb	35	10	microbes	microbe	NNS
cord-264050-6zpw6itb	35	11	into	into	IN
cord-264050-6zpw6itb	35	12	one	one	CD
cord-264050-6zpw6itb	35	13	of	of	IN
cord-264050-6zpw6itb	35	14	the	the	DT
cord-264050-6zpw6itb	35	15	original	original	JJ
cord-264050-6zpw6itb	35	16	six	six	CD
cord-264050-6zpw6itb	35	17	pathogen	pathogen	NN
cord-264050-6zpw6itb	35	18	classes	class	NNS
cord-264050-6zpw6itb	35	19	,	,	,
cord-264050-6zpw6itb	35	20	new	new	JJ
cord-264050-6zpw6itb	35	21	knowledge	knowledge	NN
cord-264050-6zpw6itb	35	22	from	from	IN
cord-264050-6zpw6itb	35	23	clinical	clinical	JJ
cord-264050-6zpw6itb	35	24	and	and	CC
cord-264050-6zpw6itb	35	25	experimental	experimental	JJ
cord-264050-6zpw6itb	35	26	studies	study	NNS
cord-264050-6zpw6itb	35	27	led	lead	VBD
cord-264050-6zpw6itb	35	28	to	to	IN
cord-264050-6zpw6itb	35	29	the	the	DT
cord-264050-6zpw6itb	35	30	conclusion	conclusion	NN
cord-264050-6zpw6itb	35	31	that	that	IN
cord-264050-6zpw6itb	35	32	some	some	DT
cord-264050-6zpw6itb	35	33	of	of	IN
cord-264050-6zpw6itb	35	34	the	the	DT
cord-264050-6zpw6itb	35	35	original	original	JJ
cord-264050-6zpw6itb	35	36	classifications	classification	NNS
cord-264050-6zpw6itb	35	37	were	be	VBD
cord-264050-6zpw6itb	35	38	incorrect	incorrect	JJ
cord-264050-6zpw6itb	35	39	.	.	.
cord-264050-6zpw6itb	36	1	Again	again	RB
cord-264050-6zpw6itb	36	2	,	,	,
cord-264050-6zpw6itb	36	3	lessons	lesson	NNS
cord-264050-6zpw6itb	36	4	learned	learn	VBN
cord-264050-6zpw6itb	36	5	from	from	IN
cord-264050-6zpw6itb	36	6	the	the	DT
cord-264050-6zpw6itb	36	7	HIV	HIV	NNP
cord-264050-6zpw6itb	36	8	/	/	SYM
cord-264050-6zpw6itb	36	9	AIDS	AIDS	NNP
cord-264050-6zpw6itb	36	10	pandemic	pandemic	NN
cord-264050-6zpw6itb	36	11	provided	provide	VBD
cord-264050-6zpw6itb	36	12	new	new	JJ
cord-264050-6zpw6itb	36	13	insights	insight	NNS
cord-264050-6zpw6itb	36	14	into	into	IN
cord-264050-6zpw6itb	36	15	microbial	microbial	JJ
cord-264050-6zpw6itb	36	16	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	36	17	,	,	,
cord-264050-6zpw6itb	36	18	perhaps	perhaps	RB
cord-264050-6zpw6itb	36	19	best	best	RB
cord-264050-6zpw6itb	36	20	exemplified	exemplify	VBN
cord-264050-6zpw6itb	36	21	by	by	IN
cord-264050-6zpw6itb	36	22	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	36	23	.	.	.
cord-264050-6zpw6itb	37	1	C.	C.	NNP
cord-264050-6zpw6itb	37	2	neoformans	neoformans	NNP
cord-264050-6zpw6itb	37	3	was	be	VBD
cord-264050-6zpw6itb	37	4	first	first	RB
cord-264050-6zpw6itb	37	5	classified	classify	VBN
cord-264050-6zpw6itb	37	6	as	as	IN
cord-264050-6zpw6itb	37	7	a	a	DT
cord-264050-6zpw6itb	37	8	class	class	NN
cord-264050-6zpw6itb	37	9	2	2	CD
cord-264050-6zpw6itb	37	10	pathogen	pathogen	NN
cord-264050-6zpw6itb	37	11	,	,	,
cord-264050-6zpw6itb	37	12	the	the	DT
cord-264050-6zpw6itb	37	13	definition	definition	NN
cord-264050-6zpw6itb	37	14	of	of	IN
cord-264050-6zpw6itb	37	15	which	which	WDT
cord-264050-6zpw6itb	37	16	was	be	VBD
cord-264050-6zpw6itb	37	17	"	"	``
cord-264050-6zpw6itb	37	18	pathogens	pathogen	NNS
cord-264050-6zpw6itb	37	19	that	that	WDT
cord-264050-6zpw6itb	37	20	cause	cause	VBP
cord-264050-6zpw6itb	37	21	damage	damage	NN
cord-264050-6zpw6itb	37	22	either	either	CC
cord-264050-6zpw6itb	37	23	in	in	IN
cord-264050-6zpw6itb	37	24	hosts	host	NNS
cord-264050-6zpw6itb	37	25	with	with	IN
cord-264050-6zpw6itb	37	26	weak	weak	JJ
cord-264050-6zpw6itb	37	27	immune	immune	JJ
cord-264050-6zpw6itb	37	28	responses	response	NNS
cord-264050-6zpw6itb	37	29	or	or	CC
cord-264050-6zpw6itb	37	30	in	in	IN
cord-264050-6zpw6itb	37	31	the	the	DT
cord-264050-6zpw6itb	37	32	setting	setting	NN
cord-264050-6zpw6itb	37	33	of	of	IN
cord-264050-6zpw6itb	37	34	normal	normal	JJ
cord-264050-6zpw6itb	37	35	immune	immune	JJ
cord-264050-6zpw6itb	37	36	responses	response	NNS
cord-264050-6zpw6itb	37	37	"	"	''
cord-264050-6zpw6itb	37	38	(	(	-LRB-
cord-264050-6zpw6itb	37	39	3	3	CD
cord-264050-6zpw6itb	37	40	)	)	-RRB-
cord-264050-6zpw6itb	37	41	.	.	.
cord-264050-6zpw6itb	38	1	This	this	DT
cord-264050-6zpw6itb	38	2	characterization	characterization	NN
cord-264050-6zpw6itb	38	3	was	be	VBD
cord-264050-6zpw6itb	38	4	consistent	consistent	JJ
cord-264050-6zpw6itb	38	5	with	with	IN
cord-264050-6zpw6itb	38	6	available	available	JJ
cord-264050-6zpw6itb	38	7	knowledge	knowledge	NN
cord-264050-6zpw6itb	38	8	in	in	IN
cord-264050-6zpw6itb	38	9	1999	1999	CD
cord-264050-6zpw6itb	38	10	.	.	.
cord-264050-6zpw6itb	39	1	However	however	RB
cord-264050-6zpw6itb	39	2	,	,	,
cord-264050-6zpw6itb	39	3	the	the	DT
cord-264050-6zpw6itb	39	4	emergence	emergence	NN
cord-264050-6zpw6itb	39	5	of	of	IN
cord-264050-6zpw6itb	39	6	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	39	7	gattii	gattii	NNP
cord-264050-6zpw6itb	39	8	in	in	IN
cord-264050-6zpw6itb	39	9	apparently	apparently	RB
cord-264050-6zpw6itb	39	10	healthy	healthy	JJ
cord-264050-6zpw6itb	39	11	persons	person	NNS
cord-264050-6zpw6itb	39	12	in	in	IN
cord-264050-6zpw6itb	39	13	the	the	DT
cord-264050-6zpw6itb	39	14	Pacific	Pacific	NNP
cord-264050-6zpw6itb	39	15	Northwest	Northwest	NNP
cord-264050-6zpw6itb	39	16	(	(	-LRB-
cord-264050-6zpw6itb	39	17	7	7	CD
cord-264050-6zpw6itb	39	18	)	)	-RRB-
cord-264050-6zpw6itb	39	19	and	and	CC
cord-264050-6zpw6itb	39	20	the	the	DT
cord-264050-6zpw6itb	39	21	unexpected	unexpected	JJ
cord-264050-6zpw6itb	39	22	appearance	appearance	NN
cord-264050-6zpw6itb	39	23	of	of	IN
cord-264050-6zpw6itb	39	24	immune	immune	JJ
cord-264050-6zpw6itb	39	25	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	39	26	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	39	27	syndrome	syndrome	NN
cord-264050-6zpw6itb	39	28	(	(	-LRB-
cord-264050-6zpw6itb	39	29	IRIS)-associated	iris)-associate	VBN
cord-264050-6zpw6itb	39	30	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	39	31	in	in	IN
cord-264050-6zpw6itb	39	32	patients	patient	NNS
cord-264050-6zpw6itb	39	33	with	with	IN
cord-264050-6zpw6itb	39	34	HIV	HIV	NNP
cord-264050-6zpw6itb	39	35	/	/	SYM
cord-264050-6zpw6itb	39	36	AIDS	AIDS	NNP
cord-264050-6zpw6itb	39	37	after	after	IN
cord-264050-6zpw6itb	39	38	initiation	initiation	NN
cord-264050-6zpw6itb	39	39	of	of	IN
cord-264050-6zpw6itb	39	40	antiretroviral	antiretroviral	JJ
cord-264050-6zpw6itb	39	41	therapy	therapy	NN
cord-264050-6zpw6itb	39	42	(	(	-LRB-
cord-264050-6zpw6itb	39	43	ART	art	NN
cord-264050-6zpw6itb	39	44	)	)	-RRB-
cord-264050-6zpw6itb	39	45	(	(	-LRB-
cord-264050-6zpw6itb	39	46	8	8	CD
cord-264050-6zpw6itb	39	47	,	,	,
cord-264050-6zpw6itb	39	48	9	9	CD
cord-264050-6zpw6itb	39	49	)	)	-RRB-
cord-264050-6zpw6itb	39	50	revealed	reveal	VBD
cord-264050-6zpw6itb	39	51	that	that	IN
cord-264050-6zpw6itb	39	52	the	the	DT
cord-264050-6zpw6itb	39	53	host	host	NN
cord-264050-6zpw6itb	39	54	immune	immune	JJ
cord-264050-6zpw6itb	39	55	response	response	NN
cord-264050-6zpw6itb	39	56	itself	-PRON-	PRP
cord-264050-6zpw6itb	39	57	can	can	MD
cord-264050-6zpw6itb	39	58	contribute	contribute	VB
cord-264050-6zpw6itb	39	59	to	to	IN
cord-264050-6zpw6itb	39	60	the	the	DT
cord-264050-6zpw6itb	39	61	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	39	62	of	of	IN
cord-264050-6zpw6itb	39	63	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	39	64	.	.	.
cord-264050-6zpw6itb	40	1	Thus	thus	RB
cord-264050-6zpw6itb	40	2	,	,	,
cord-264050-6zpw6itb	40	3	classification	classification	NN
cord-264050-6zpw6itb	40	4	of	of	IN
cord-264050-6zpw6itb	40	5	C.	C.	NNP
cord-264050-6zpw6itb	40	6	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	40	7	as	as	IN
cord-264050-6zpw6itb	40	8	a	a	DT
cord-264050-6zpw6itb	40	9	class	class	NN
cord-264050-6zpw6itb	40	10	2	2	CD
cord-264050-6zpw6itb	40	11	pathogen	pathogen	NN
cord-264050-6zpw6itb	40	12	needed	need	VBN
cord-264050-6zpw6itb	40	13	to	to	TO
cord-264050-6zpw6itb	40	14	be	be	VB
cord-264050-6zpw6itb	40	15	revisited	revisit	VBN
cord-264050-6zpw6itb	40	16	.	.	.
cord-264050-6zpw6itb	41	1	Another	another	DT
cord-264050-6zpw6itb	41	2	example	example	NN
cord-264050-6zpw6itb	41	3	of	of	IN
cord-264050-6zpw6itb	41	4	a	a	DT
cord-264050-6zpw6itb	41	5	pathogen	pathogen	NN
cord-264050-6zpw6itb	41	6	needing	need	VBG
cord-264050-6zpw6itb	41	7	reclassification	reclassification	NN
cord-264050-6zpw6itb	41	8	is	be	VBZ
cord-264050-6zpw6itb	41	9	Pneumocystis	Pneumocystis	NNP
cord-264050-6zpw6itb	41	10	jirovecii	jirovecii	NNP
cord-264050-6zpw6itb	41	11	,	,	,
cord-264050-6zpw6itb	41	12	which	which	WDT
cord-264050-6zpw6itb	41	13	was	be	VBD
cord-264050-6zpw6itb	41	14	originally	originally	RB
cord-264050-6zpw6itb	41	15	classified	classify	VBN
cord-264050-6zpw6itb	41	16	as	as	IN
cord-264050-6zpw6itb	41	17	a	a	DT
cord-264050-6zpw6itb	41	18	class	class	NN
cord-264050-6zpw6itb	41	19	1	1	CD
cord-264050-6zpw6itb	41	20	pathogen	pathogen	NN
cord-264050-6zpw6itb	41	21	,	,	,
cord-264050-6zpw6itb	41	22	defined	define	VBN
cord-264050-6zpw6itb	41	23	as	as	IN
cord-264050-6zpw6itb	41	24	"	"	``
cord-264050-6zpw6itb	41	25	pathogens	pathogen	NNS
cord-264050-6zpw6itb	41	26	that	that	WDT
cord-264050-6zpw6itb	41	27	cause	cause	VBP
cord-264050-6zpw6itb	41	28	damage	damage	NN
cord-264050-6zpw6itb	41	29	only	only	RB
cord-264050-6zpw6itb	41	30	in	in	IN
cord-264050-6zpw6itb	41	31	the	the	DT
cord-264050-6zpw6itb	41	32	setting	setting	NN
cord-264050-6zpw6itb	41	33	of	of	IN
cord-264050-6zpw6itb	41	34	weak	weak	JJ
cord-264050-6zpw6itb	41	35	immune	immune	JJ
cord-264050-6zpw6itb	41	36	responses	response	NNS
cord-264050-6zpw6itb	41	37	"	"	''
cord-264050-6zpw6itb	41	38	(	(	-LRB-
cord-264050-6zpw6itb	41	39	3	3	CD
cord-264050-6zpw6itb	41	40	)	)	-RRB-
cord-264050-6zpw6itb	41	41	.	.	.
cord-264050-6zpw6itb	42	1	However	however	RB
cord-264050-6zpw6itb	42	2	,	,	,
cord-264050-6zpw6itb	42	3	pneumocystis	pneumocystis	NN
cord-264050-6zpw6itb	42	4	pneumonia	pneumonia	NN
cord-264050-6zpw6itb	42	5	is	be	VBZ
cord-264050-6zpw6itb	42	6	associated	associate	VBN
cord-264050-6zpw6itb	42	7	with	with	IN
cord-264050-6zpw6itb	42	8	intense	intense	JJ
cord-264050-6zpw6itb	42	9	inflammation	inflammation	NN
cord-264050-6zpw6itb	42	10	in	in	IN
cord-264050-6zpw6itb	42	11	children	child	NNS
cord-264050-6zpw6itb	42	12	and	and	CC
cord-264050-6zpw6itb	42	13	after	after	IN
cord-264050-6zpw6itb	42	14	initiation	initiation	NN
cord-264050-6zpw6itb	42	15	of	of	IN
cord-264050-6zpw6itb	42	16	therapy	therapy	NN
cord-264050-6zpw6itb	42	17	in	in	IN
cord-264050-6zpw6itb	42	18	patients	patient	NNS
cord-264050-6zpw6itb	42	19	with	with	IN
cord-264050-6zpw6itb	42	20	HIV	HIV	NNP
cord-264050-6zpw6itb	42	21	/	/	SYM
cord-264050-6zpw6itb	42	22	AIDS	AIDS	NNP
cord-264050-6zpw6itb	42	23	(	(	-LRB-
cord-264050-6zpw6itb	42	24	10	10	CD
cord-264050-6zpw6itb	42	25	,	,	,
cord-264050-6zpw6itb	42	26	11	11	CD
cord-264050-6zpw6itb	42	27	)	)	-RRB-
cord-264050-6zpw6itb	42	28	.	.	.
cord-264050-6zpw6itb	43	1	In	in	IN
cord-264050-6zpw6itb	43	2	fact	fact	NN
cord-264050-6zpw6itb	43	3	,	,	,
cord-264050-6zpw6itb	43	4	a	a	DT
cord-264050-6zpw6itb	43	5	major	major	JJ
cord-264050-6zpw6itb	43	6	advance	advance	NN
cord-264050-6zpw6itb	43	7	in	in	IN
cord-264050-6zpw6itb	43	8	treating	treat	VBG
cord-264050-6zpw6itb	43	9	pneumocystis	pneumocystis	NN
cord-264050-6zpw6itb	43	10	pneumonia	pneumonia	NN
cord-264050-6zpw6itb	43	11	was	be	VBD
cord-264050-6zpw6itb	43	12	the	the	DT
cord-264050-6zpw6itb	43	13	realization	realization	NN
cord-264050-6zpw6itb	43	14	that	that	IN
cord-264050-6zpw6itb	43	15	corticosteroid	corticosteroid	NN
cord-264050-6zpw6itb	43	16	therapy	therapy	NN
cord-264050-6zpw6itb	43	17	reduced	reduce	VBD
cord-264050-6zpw6itb	43	18	morbidity	morbidity	NN
cord-264050-6zpw6itb	43	19	and	and	CC
cord-264050-6zpw6itb	43	20	mortality	mortality	NN
cord-264050-6zpw6itb	43	21	,	,	,
cord-264050-6zpw6itb	43	22	a	a	DT
cord-264050-6zpw6itb	43	23	finding	finding	NN
cord-264050-6zpw6itb	43	24	that	that	WDT
cord-264050-6zpw6itb	43	25	was	be	VBD
cord-264050-6zpw6itb	43	26	counterintuitive	counterintuitive	JJ
cord-264050-6zpw6itb	43	27	,	,	,
cord-264050-6zpw6itb	43	28	since	since	IN
cord-264050-6zpw6itb	43	29	this	this	DT
cord-264050-6zpw6itb	43	30	disease	disease	NN
cord-264050-6zpw6itb	43	31	arose	arise	VBD
cord-264050-6zpw6itb	43	32	in	in	IN
cord-264050-6zpw6itb	43	33	the	the	DT
cord-264050-6zpw6itb	43	34	setting	setting	NN
cord-264050-6zpw6itb	43	35	of	of	IN
cord-264050-6zpw6itb	43	36	profound	profound	JJ
cord-264050-6zpw6itb	43	37	HIV	HIV	NNP
cord-264050-6zpw6itb	43	38	-	-	HYPH
cord-264050-6zpw6itb	43	39	associated	associate	VBN
cord-264050-6zpw6itb	43	40	immunodeficiency	immunodeficiency	NN
cord-264050-6zpw6itb	43	41	.	.	.
cord-264050-6zpw6itb	44	1	Thus	thus	RB
cord-264050-6zpw6itb	44	2	,	,	,
cord-264050-6zpw6itb	44	3	inflammation	inflammation	NN
cord-264050-6zpw6itb	44	4	may	may	MD
cord-264050-6zpw6itb	44	5	drive	drive	VB
cord-264050-6zpw6itb	44	6	pneumocystis	pneumocystis	NN
cord-264050-6zpw6itb	44	7	-	-	:
cord-264050-6zpw6itb	44	8	and	and	CC
cord-264050-6zpw6itb	44	9	cryptococcus	cryptococcus	NN
cord-264050-6zpw6itb	44	10	-	-	HYPH
cord-264050-6zpw6itb	44	11	mediated	mediate	VBN
cord-264050-6zpw6itb	44	12	damage	damage	NN
cord-264050-6zpw6itb	44	13	,	,	,
cord-264050-6zpw6itb	44	14	even	even	RB
cord-264050-6zpw6itb	44	15	in	in	IN
cord-264050-6zpw6itb	44	16	patients	patient	NNS
cord-264050-6zpw6itb	44	17	with	with	IN
cord-264050-6zpw6itb	44	18	severely	severely	RB
cord-264050-6zpw6itb	44	19	impaired	impair	VBN
cord-264050-6zpw6itb	44	20	immunity	immunity	NN
cord-264050-6zpw6itb	44	21	,	,	,
cord-264050-6zpw6itb	44	22	defying	defy	VBG
cord-264050-6zpw6itb	44	23	their	-PRON-	PRP$
cord-264050-6zpw6itb	44	24	initial	initial	JJ
cord-264050-6zpw6itb	44	25	classifications	classification	NNS
cord-264050-6zpw6itb	44	26	as	as	IN
cord-264050-6zpw6itb	44	27	class	class	NN
cord-264050-6zpw6itb	44	28	1	1	CD
cord-264050-6zpw6itb	44	29	and	and	CC
cord-264050-6zpw6itb	44	30	2	2	CD
cord-264050-6zpw6itb	44	31	pathogens	pathogen	NNS
cord-264050-6zpw6itb	44	32	,	,	,
cord-264050-6zpw6itb	44	33	respectively	respectively	RB
cord-264050-6zpw6itb	44	34	.	.	.
cord-264050-6zpw6itb	45	1	Although	although	IN
cord-264050-6zpw6itb	45	2	one	one	PRP
cord-264050-6zpw6itb	45	3	might	may	MD
cord-264050-6zpw6itb	45	4	propose	propose	VB
cord-264050-6zpw6itb	45	5	that	that	IN
cord-264050-6zpw6itb	45	6	these	these	DT
cord-264050-6zpw6itb	45	7	microbes	microbe	NNS
cord-264050-6zpw6itb	45	8	be	be	VB
cord-264050-6zpw6itb	45	9	reclassified	reclassify	VBN
cord-264050-6zpw6itb	45	10	as	as	IN
cord-264050-6zpw6itb	45	11	class	class	NN
cord-264050-6zpw6itb	45	12	3	3	CD
cord-264050-6zpw6itb	45	13	pathogens	pathogen	NNS
cord-264050-6zpw6itb	45	14	,	,	,
cord-264050-6zpw6itb	45	15	"	"	''
cord-264050-6zpw6itb	45	16	pathogens	pathogen	NNS
cord-264050-6zpw6itb	45	17	that	that	WDT
cord-264050-6zpw6itb	45	18	cause	cause	VBP
cord-264050-6zpw6itb	45	19	damage	damage	NN
cord-264050-6zpw6itb	45	20	in	in	IN
cord-264050-6zpw6itb	45	21	the	the	DT
cord-264050-6zpw6itb	45	22	setting	setting	NN
cord-264050-6zpw6itb	45	23	of	of	IN
cord-264050-6zpw6itb	45	24	appropriate	appropriate	JJ
cord-264050-6zpw6itb	45	25	immune	immune	JJ
cord-264050-6zpw6itb	45	26	responses	response	NNS
cord-264050-6zpw6itb	45	27	and	and	CC
cord-264050-6zpw6itb	45	28	cause	cause	VB
cord-264050-6zpw6itb	45	29	damage	damage	NN
cord-264050-6zpw6itb	45	30	at	at	IN
cord-264050-6zpw6itb	45	31	both	both	DT
cord-264050-6zpw6itb	45	32	ends	end	NNS
cord-264050-6zpw6itb	45	33	of	of	IN
cord-264050-6zpw6itb	45	34	the	the	DT
cord-264050-6zpw6itb	45	35	continuum	continuum	NN
cord-264050-6zpw6itb	45	36	of	of	IN
cord-264050-6zpw6itb	45	37	immune	immune	JJ
cord-264050-6zpw6itb	45	38	response	response	NN
cord-264050-6zpw6itb	45	39	"	"	''
cord-264050-6zpw6itb	45	40	(	(	-LRB-
cord-264050-6zpw6itb	45	41	3	3	CD
cord-264050-6zpw6itb	45	42	)	)	-RRB-
cord-264050-6zpw6itb	46	1	,	,	,
cord-264050-6zpw6itb	46	2	most	most	JJS
cord-264050-6zpw6itb	46	3	persons	person	NNS
cord-264050-6zpw6itb	46	4	with	with	IN
cord-264050-6zpw6itb	46	5	normal	normal	JJ
cord-264050-6zpw6itb	46	6	immune	immune	JJ
cord-264050-6zpw6itb	46	7	responses	response	NNS
cord-264050-6zpw6itb	46	8	never	never	RB
cord-264050-6zpw6itb	46	9	exhibit	exhibit	VBP
cord-264050-6zpw6itb	46	10	clinically	clinically	RB
cord-264050-6zpw6itb	46	11	detected	detect	VBN
cord-264050-6zpw6itb	46	12	damage	damage	NN
cord-264050-6zpw6itb	46	13	as	as	IN
cord-264050-6zpw6itb	46	14	an	an	DT
cord-264050-6zpw6itb	46	15	outcome	outcome	NN
cord-264050-6zpw6itb	46	16	of	of	IN
cord-264050-6zpw6itb	46	17	interaction	interaction	NN
cord-264050-6zpw6itb	46	18	with	with	IN
cord-264050-6zpw6itb	46	19	these	these	DT
cord-264050-6zpw6itb	46	20	microbes	microbe	NNS
cord-264050-6zpw6itb	46	21	.	.	.
cord-264050-6zpw6itb	47	1	These	these	DT
cord-264050-6zpw6itb	47	2	examples	example	NNS
cord-264050-6zpw6itb	47	3	highlight	highlight	VBP
cord-264050-6zpw6itb	47	4	limitations	limitation	NNS
cord-264050-6zpw6itb	47	5	of	of	IN
cord-264050-6zpw6itb	47	6	the	the	DT
cord-264050-6zpw6itb	47	7	original	original	JJ
cord-264050-6zpw6itb	47	8	DRF	DRF	NNP
cord-264050-6zpw6itb	47	9	pathogen	pathogen	NN
cord-264050-6zpw6itb	47	10	classes	class	NNS
cord-264050-6zpw6itb	47	11	and	and	CC
cord-264050-6zpw6itb	47	12	illustrate	illustrate	VBP
cord-264050-6zpw6itb	47	13	that	that	IN
cord-264050-6zpw6itb	47	14	each	each	DT
cord-264050-6zpw6itb	47	15	of	of	IN
cord-264050-6zpw6itb	47	16	the	the	DT
cord-264050-6zpw6itb	47	17	six	six	CD
cord-264050-6zpw6itb	47	18	classes	class	NNS
cord-264050-6zpw6itb	47	19	is	be	VBZ
cord-264050-6zpw6itb	47	20	actually	actually	RB
cord-264050-6zpw6itb	47	21	a	a	DT
cord-264050-6zpw6itb	47	22	derivative	derivative	NN
cord-264050-6zpw6itb	47	23	of	of	IN
cord-264050-6zpw6itb	47	24	a	a	DT
cord-264050-6zpw6itb	47	25	single	single	JJ
cord-264050-6zpw6itb	47	26	parabola	parabola	NN
cord-264050-6zpw6itb	47	27	that	that	WDT
cord-264050-6zpw6itb	47	28	can	can	MD
cord-264050-6zpw6itb	47	29	shift	shift	VB
cord-264050-6zpw6itb	47	30	to	to	IN
cord-264050-6zpw6itb	47	31	the	the	DT
cord-264050-6zpw6itb	47	32	left	left	JJ
cord-264050-6zpw6itb	47	33	,	,	,
cord-264050-6zpw6itb	47	34	right	right	UH
cord-264050-6zpw6itb	47	35	,	,	,
cord-264050-6zpw6itb	47	36	up	up	RB
cord-264050-6zpw6itb	47	37	,	,	,
cord-264050-6zpw6itb	47	38	or	or	CC
cord-264050-6zpw6itb	47	39	down	down	RB
cord-264050-6zpw6itb	47	40	to	to	TO
cord-264050-6zpw6itb	47	41	depict	depict	VB
cord-264050-6zpw6itb	47	42	the	the	DT
cord-264050-6zpw6itb	47	43	impact	impact	NN
cord-264050-6zpw6itb	47	44	of	of	IN
cord-264050-6zpw6itb	47	45	the	the	DT
cord-264050-6zpw6itb	47	46	immune	immune	JJ
cord-264050-6zpw6itb	47	47	response	response	NN
cord-264050-6zpw6itb	47	48	on	on	IN
cord-264050-6zpw6itb	47	49	disease	disease	NN
cord-264050-6zpw6itb	47	50	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	47	51	(	(	-LRB-
cord-264050-6zpw6itb	47	52	Fig	fig	NN
cord-264050-6zpw6itb	47	53	.	.	.
cord-264050-6zpw6itb	47	54	1	1	CD
cord-264050-6zpw6itb	47	55	)	)	-RRB-
cord-264050-6zpw6itb	47	56	.	.	.
cord-264050-6zpw6itb	48	1	The	the	DT
cord-264050-6zpw6itb	48	2	emergence	emergence	NN
cord-264050-6zpw6itb	48	3	of	of	IN
cord-264050-6zpw6itb	48	4	IRIS	IRIS	NNP
cord-264050-6zpw6itb	48	5	-	-	HYPH
cord-264050-6zpw6itb	48	6	associated	associate	VBN
cord-264050-6zpw6itb	48	7	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	48	8	in	in	IN
cord-264050-6zpw6itb	48	9	the	the	DT
cord-264050-6zpw6itb	48	10	setting	setting	NN
cord-264050-6zpw6itb	48	11	of	of	IN
cord-264050-6zpw6itb	48	12	ART	art	NN
cord-264050-6zpw6itb	48	13	initiation	initiation	NN
cord-264050-6zpw6itb	48	14	provided	provide	VBD
cord-264050-6zpw6itb	48	15	clear	clear	JJ
cord-264050-6zpw6itb	48	16	evidence	evidence	NN
cord-264050-6zpw6itb	48	17	that	that	IN
cord-264050-6zpw6itb	48	18	host	host	NN
cord-264050-6zpw6itb	48	19	damage	damage	NN
cord-264050-6zpw6itb	48	20	in	in	IN
cord-264050-6zpw6itb	48	21	patients	patient	NNS
cord-264050-6zpw6itb	48	22	with	with	IN
cord-264050-6zpw6itb	48	23	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	48	24	disease	disease	NN
cord-264050-6zpw6itb	48	25	may	may	MD
cord-264050-6zpw6itb	48	26	be	be	VB
cord-264050-6zpw6itb	48	27	driven	drive	VBN
cord-264050-6zpw6itb	48	28	by	by	IN
cord-264050-6zpw6itb	48	29	inflammation	inflammation	NN
cord-264050-6zpw6itb	48	30	(	(	-LRB-
cord-264050-6zpw6itb	48	31	12	12	CD
cord-264050-6zpw6itb	48	32	)	)	-RRB-
cord-264050-6zpw6itb	48	33	.	.	.
cord-264050-6zpw6itb	49	1	IRIS	IRIS	NNP
cord-264050-6zpw6itb	49	2	often	often	RB
cord-264050-6zpw6itb	49	3	occurred	occur	VBD
cord-264050-6zpw6itb	49	4	in	in	IN
cord-264050-6zpw6itb	49	5	patients	patient	NNS
cord-264050-6zpw6itb	49	6	with	with	IN
cord-264050-6zpw6itb	49	7	very	very	RB
cord-264050-6zpw6itb	49	8	low	low	JJ
cord-264050-6zpw6itb	49	9	initial	initial	JJ
cord-264050-6zpw6itb	49	10	cerebrospinal	cerebrospinal	NN
cord-264050-6zpw6itb	49	11	fluid	fluid	NN
cord-264050-6zpw6itb	49	12	(	(	-LRB-
cord-264050-6zpw6itb	49	13	CSF	CSF	NNP
cord-264050-6zpw6itb	49	14	)	)	-RRB-
cord-264050-6zpw6itb	49	15	lymphocyte	lymphocyte	NN
cord-264050-6zpw6itb	49	16	counts	count	NNS
cord-264050-6zpw6itb	49	17	(	(	-LRB-
cord-264050-6zpw6itb	49	18	8)	8)	NNP
cord-264050-6zpw6itb	49	19	,	,	,
cord-264050-6zpw6itb	49	20	and	and	CC
cord-264050-6zpw6itb	49	21	has	have	VBZ
cord-264050-6zpw6itb	49	22	been	be	VBN
cord-264050-6zpw6itb	49	23	associated	associate	VBN
cord-264050-6zpw6itb	49	24	with	with	IN
cord-264050-6zpw6itb	49	25	chemokine	chemokine	NN
cord-264050-6zpw6itb	49	26	dysregulation	dysregulation	NN
cord-264050-6zpw6itb	49	27	(	(	-LRB-
cord-264050-6zpw6itb	49	28	13	13	CD
cord-264050-6zpw6itb	49	29	)	)	-RRB-
cord-264050-6zpw6itb	49	30	and	and	CC
cord-264050-6zpw6itb	49	31	activated	activate	VBD
cord-264050-6zpw6itb	49	32	CD4	CD4	NNP
cord-264050-6zpw6itb	49	33	ϩ	ϩ	NNP
cord-264050-6zpw6itb	49	34	T	t	NN
cord-264050-6zpw6itb	49	35	cells	cell	NNS
cord-264050-6zpw6itb	49	36	and	and	CC
cord-264050-6zpw6itb	49	37	macrophages	macrophage	NNS
cord-264050-6zpw6itb	49	38	(	(	-LRB-
cord-264050-6zpw6itb	49	39	12	12	CD
cord-264050-6zpw6itb	49	40	,	,	,
cord-264050-6zpw6itb	49	41	14	14	CD
cord-264050-6zpw6itb	49	42	,	,	,
cord-264050-6zpw6itb	49	43	15	15	CD
cord-264050-6zpw6itb	49	44	)	)	-RRB-
cord-264050-6zpw6itb	49	45	.	.	.
cord-264050-6zpw6itb	50	1	Similar	similar	JJ
cord-264050-6zpw6itb	50	2	findings	finding	NNS
cord-264050-6zpw6itb	50	3	have	have	VBP
cord-264050-6zpw6itb	50	4	also	also	RB
cord-264050-6zpw6itb	50	5	been	be	VBN
cord-264050-6zpw6itb	50	6	reported	report	VBN
cord-264050-6zpw6itb	50	7	in	in	IN
cord-264050-6zpw6itb	50	8	some	some	DT
cord-264050-6zpw6itb	50	9	non	non	JJ
cord-264050-6zpw6itb	50	10	-	-	JJ
cord-264050-6zpw6itb	50	11	HIV	hiv	JJ
cord-264050-6zpw6itb	50	12	-	-	HYPH
cord-264050-6zpw6itb	50	13	infected	infect	VBN
cord-264050-6zpw6itb	50	14	patients	patient	NNS
cord-264050-6zpw6itb	50	15	with	with	IN
cord-264050-6zpw6itb	50	16	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	50	17	meningitis	meningitis	NN
cord-264050-6zpw6itb	50	18	(	(	-LRB-
cord-264050-6zpw6itb	50	19	16	16	CD
cord-264050-6zpw6itb	50	20	,	,	,
cord-264050-6zpw6itb	50	21	17	17	CD
cord-264050-6zpw6itb	50	22	)	)	-RRB-
cord-264050-6zpw6itb	50	23	.	.	.
cord-264050-6zpw6itb	51	1	A	a	DT
cord-264050-6zpw6itb	51	2	role	role	NN
cord-264050-6zpw6itb	51	3	for	for	IN
cord-264050-6zpw6itb	51	4	CD4	CD4	NNP
cord-264050-6zpw6itb	51	5	ϩ	ϩ	NNP
cord-264050-6zpw6itb	51	6	T	t	NN
cord-264050-6zpw6itb	51	7	cells	cell	NNS
cord-264050-6zpw6itb	51	8	in	in	IN
cord-264050-6zpw6itb	51	9	the	the	DT
cord-264050-6zpw6itb	51	10	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	51	11	of	of	IN
cord-264050-6zpw6itb	51	12	cryptococcusassociated	cryptococcusassociate	VBN
cord-264050-6zpw6itb	51	13	IRIS	IRIS	NNP
cord-264050-6zpw6itb	51	14	has	have	VBZ
cord-264050-6zpw6itb	51	15	also	also	RB
cord-264050-6zpw6itb	51	16	been	be	VBN
cord-264050-6zpw6itb	51	17	demonstrated	demonstrate	VBN
cord-264050-6zpw6itb	51	18	in	in	IN
cord-264050-6zpw6itb	51	19	experimental	experimental	JJ
cord-264050-6zpw6itb	51	20	mouse	mouse	NN
cord-264050-6zpw6itb	51	21	models	model	NNS
cord-264050-6zpw6itb	51	22	.	.	.
cord-264050-6zpw6itb	52	1	Eschke	Eschke	NNP
cord-264050-6zpw6itb	52	2	and	and	CC
cord-264050-6zpw6itb	52	3	colleagues	colleague	NNS
cord-264050-6zpw6itb	52	4	induced	induce	VBD
cord-264050-6zpw6itb	52	5	IRIS	IRIS	NNP
cord-264050-6zpw6itb	52	6	in	in	IN
cord-264050-6zpw6itb	52	7	RAG1	RAG1	NNP
cord-264050-6zpw6itb	52	8	Ϫ/Ϫ	Ϫ/Ϫ	NNPS
cord-264050-6zpw6itb	52	9	mice	mouse	NNS
cord-264050-6zpw6itb	52	10	by	by	IN
cord-264050-6zpw6itb	52	11	reconstituting	reconstitute	VBG
cord-264050-6zpw6itb	52	12	them	-PRON-	PRP
cord-264050-6zpw6itb	52	13	with	with	IN
cord-264050-6zpw6itb	52	14	naive	naive	JJ
cord-264050-6zpw6itb	52	15	(	(	-LRB-
cord-264050-6zpw6itb	52	16	wild	wild	JJ
cord-264050-6zpw6itb	52	17	-	-	HYPH
cord-264050-6zpw6itb	52	18	type	type	NN
cord-264050-6zpw6itb	52	19	)	)	-RRB-
cord-264050-6zpw6itb	53	1	CD4	CD4	NNP
cord-264050-6zpw6itb	53	2	ϩ	ϩ	NNP
cord-264050-6zpw6itb	53	3	T	t	NN
cord-264050-6zpw6itb	53	4	cells	cell	NNS
cord-264050-6zpw6itb	53	5	1	1	CD
cord-264050-6zpw6itb	53	6	month	month	NN
cord-264050-6zpw6itb	53	7	after	after	IN
cord-264050-6zpw6itb	53	8	pulmonary	pulmonary	JJ
cord-264050-6zpw6itb	53	9	infection	infection	NN
cord-264050-6zpw6itb	53	10	with	with	IN
cord-264050-6zpw6itb	53	11	500	500	CD
cord-264050-6zpw6itb	53	12	CFU	CFU	NNP
cord-264050-6zpw6itb	53	13	of	of	IN
cord-264050-6zpw6itb	53	14	C.	C.	NNP
cord-264050-6zpw6itb	53	15	neoformans	neoformans	NNP
cord-264050-6zpw6itb	53	16	(	(	-LRB-
cord-264050-6zpw6itb	53	17	18	18	CD
cord-264050-6zpw6itb	53	18	)	)	-RRB-
cord-264050-6zpw6itb	53	19	.	.	.
cord-264050-6zpw6itb	54	1	In	in	IN
cord-264050-6zpw6itb	54	2	this	this	DT
cord-264050-6zpw6itb	54	3	model	model	NN
cord-264050-6zpw6itb	54	4	,	,	,
cord-264050-6zpw6itb	54	5	mice	mouse	NNS
cord-264050-6zpw6itb	54	6	developed	develop	VBD
cord-264050-6zpw6itb	54	7	wasting	waste	VBG
cord-264050-6zpw6itb	54	8	and	and	CC
cord-264050-6zpw6itb	54	9	systemic	systemic	JJ
cord-264050-6zpw6itb	54	10	inflammation	inflammation	NN
cord-264050-6zpw6itb	54	11	evidenced	evidence	VBN
cord-264050-6zpw6itb	54	12	by	by	IN
cord-264050-6zpw6itb	54	13	high	high	JJ
cord-264050-6zpw6itb	54	14	levels	level	NNS
cord-264050-6zpw6itb	54	15	of	of	IN
cord-264050-6zpw6itb	54	16	Th1-type	Th1-type	NNP
cord-264050-6zpw6itb	54	17	cytokines	cytokine	NNS
cord-264050-6zpw6itb	54	18	(	(	-LRB-
cord-264050-6zpw6itb	54	19	interleukin	interleukin	NN
cord-264050-6zpw6itb	54	20	6	6	CD
cord-264050-6zpw6itb	54	21	[	[	-LRB-
cord-264050-6zpw6itb	54	22	IL-6	IL-6	NNP
cord-264050-6zpw6itb	54	23	]	]	-RRB-
cord-264050-6zpw6itb	54	24	,	,	,
cord-264050-6zpw6itb	54	25	tumor	tumor	NN
cord-264050-6zpw6itb	54	26	necrosis	necrosis	NN
cord-264050-6zpw6itb	54	27	factor	factor	NN
cord-264050-6zpw6itb	54	28	alpha	alpha	NN
cord-264050-6zpw6itb	54	29	[	[	-LRB-
cord-264050-6zpw6itb	54	30	TNF-	TNF-	NNP
cord-264050-6zpw6itb	54	31	␣	␣	NN
cord-264050-6zpw6itb	54	32	]	]	-RRB-
cord-264050-6zpw6itb	54	33	,	,	,
cord-264050-6zpw6itb	54	34	and	and	CC
cord-264050-6zpw6itb	54	35	gamma	gamma	NN
cord-264050-6zpw6itb	54	36	interferon	interferon	NN
cord-264050-6zpw6itb	55	1	[	[	-LRB-
cord-264050-6zpw6itb	55	2	IFN-	IFN-	NNP
cord-264050-6zpw6itb	55	3	␥	␥	NNP
cord-264050-6zpw6itb	55	4	]	]	-RRB-
cord-264050-6zpw6itb	55	5	)	)	-RRB-
cord-264050-6zpw6itb	55	6	,	,	,
cord-264050-6zpw6itb	55	7	activated	activate	VBD
cord-264050-6zpw6itb	55	8	CD4	CD4	NNP
cord-264050-6zpw6itb	55	9	ϩ	ϩ	NNP
cord-264050-6zpw6itb	55	10	T	t	NN
cord-264050-6zpw6itb	55	11	cells	cell	NNS
cord-264050-6zpw6itb	55	12	,	,	,
cord-264050-6zpw6itb	55	13	and	and	CC
cord-264050-6zpw6itb	55	14	granulomatous	granulomatous	JJ
cord-264050-6zpw6itb	55	15	inflammation	inflammation	NN
cord-264050-6zpw6itb	55	16	in	in	IN
cord-264050-6zpw6itb	55	17	the	the	DT
cord-264050-6zpw6itb	55	18	liver	liver	NN
cord-264050-6zpw6itb	55	19	compared	compare	VBN
cord-264050-6zpw6itb	55	20	to	to	TO
cord-264050-6zpw6itb	55	21	control	control	VB
cord-264050-6zpw6itb	55	22	mice	mouse	NNS
cord-264050-6zpw6itb	55	23	that	that	WDT
cord-264050-6zpw6itb	55	24	did	do	VBD
cord-264050-6zpw6itb	55	25	not	not	RB
cord-264050-6zpw6itb	55	26	receive	receive	VB
cord-264050-6zpw6itb	55	27	CD4	CD4	NNP
cord-264050-6zpw6itb	55	28	ϩ	ϩ	NNP
cord-264050-6zpw6itb	55	29	T	t	NN
cord-264050-6zpw6itb	55	30	cells	cell	NNS
cord-264050-6zpw6itb	55	31	(	(	-LRB-
cord-264050-6zpw6itb	55	32	and	and	CC
cord-264050-6zpw6itb	55	33	mice	mouse	NNS
cord-264050-6zpw6itb	55	34	that	that	WDT
cord-264050-6zpw6itb	55	35	received	receive	VBD
cord-264050-6zpw6itb	55	36	CD4	CD4	NNP
cord-264050-6zpw6itb	55	37	ϩ	ϩ	NNP
cord-264050-6zpw6itb	55	38	T	t	NN
cord-264050-6zpw6itb	55	39	cells	cell	NNS
cord-264050-6zpw6itb	55	40	and	and	CC
cord-264050-6zpw6itb	55	41	were	be	VBD
cord-264050-6zpw6itb	55	42	not	not	RB
cord-264050-6zpw6itb	55	43	infected	infect	VBN
cord-264050-6zpw6itb	55	44	)	)	-RRB-
cord-264050-6zpw6itb	55	45	.	.	.
cord-264050-6zpw6itb	56	1	Reconstitution	reconstitution	NN
cord-264050-6zpw6itb	56	2	did	do	VBD
cord-264050-6zpw6itb	56	3	not	not	RB
cord-264050-6zpw6itb	56	4	affect	affect	VB
cord-264050-6zpw6itb	56	5	fungal	fungal	JJ
cord-264050-6zpw6itb	56	6	clearance	clearance	NN
cord-264050-6zpw6itb	56	7	.	.	.
cord-264050-6zpw6itb	57	1	This	this	DT
cord-264050-6zpw6itb	57	2	model	model	NN
cord-264050-6zpw6itb	57	3	demonstrated	demonstrate	VBD
cord-264050-6zpw6itb	57	4	that	that	IN
cord-264050-6zpw6itb	57	5	CD4	CD4	NNP
cord-264050-6zpw6itb	57	6	ϩ	ϩ	NNP
cord-264050-6zpw6itb	57	7	T	T	NNP
cord-264050-6zpw6itb	57	8	cell	cell	NN
cord-264050-6zpw6itb	57	9	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	57	10	induced	induce	VBD
cord-264050-6zpw6itb	57	11	systemic	systemic	JJ
cord-264050-6zpw6itb	57	12	inflammation	inflammation	NN
cord-264050-6zpw6itb	57	13	in	in	IN
cord-264050-6zpw6itb	57	14	C.	C.	NNP
cord-264050-6zpw6itb	57	15	neoformans	neoformans	NNP
cord-264050-6zpw6itb	57	16	-	-	HYPH
cord-264050-6zpw6itb	57	17	infected	infect	VBN
cord-264050-6zpw6itb	57	18	mice	mouse	NNS
cord-264050-6zpw6itb	57	19	that	that	WDT
cord-264050-6zpw6itb	57	20	closely	closely	RB
cord-264050-6zpw6itb	57	21	resembled	resemble	VBD
cord-264050-6zpw6itb	57	22	ART	art	NN
cord-264050-6zpw6itb	57	23	-	-	HYPH
cord-264050-6zpw6itb	57	24	induced	induce	VBN
cord-264050-6zpw6itb	57	25	IRIS	IRIS	NNP
cord-264050-6zpw6itb	57	26	in	in	IN
cord-264050-6zpw6itb	57	27	HIV	HIV	NNP
cord-264050-6zpw6itb	57	28	-	-	HYPH
cord-264050-6zpw6itb	57	29	infected	infect	VBN
cord-264050-6zpw6itb	57	30	patients	patient	NNS
cord-264050-6zpw6itb	57	31	with	with	IN
cord-264050-6zpw6itb	57	32	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	57	33	.	.	.
cord-264050-6zpw6itb	58	1	Neal	Neal	NNP
cord-264050-6zpw6itb	58	2	and	and	CC
cord-264050-6zpw6itb	58	3	colleagues	colleague	NNS
cord-264050-6zpw6itb	58	4	(	(	-LRB-
cord-264050-6zpw6itb	58	5	2	2	LS
cord-264050-6zpw6itb	58	6	)	)	-RRB-
cord-264050-6zpw6itb	58	7	describe	describe	VB
cord-264050-6zpw6itb	58	8	another	another	DT
cord-264050-6zpw6itb	58	9	mouse	mouse	NN
cord-264050-6zpw6itb	58	10	model	model	NN
cord-264050-6zpw6itb	58	11	in	in	IN
cord-264050-6zpw6itb	58	12	which	which	WDT
cord-264050-6zpw6itb	58	13	CD4	CD4	NNP
cord-264050-6zpw6itb	58	14	ϩ	ϩ	NNP
cord-264050-6zpw6itb	58	15	T	t	NN
cord-264050-6zpw6itb	58	16	cells	cell	NNS
cord-264050-6zpw6itb	58	17	mediate	mediate	VBP
cord-264050-6zpw6itb	58	18	inflammation	inflammation	NN
cord-264050-6zpw6itb	58	19	and	and	CC
cord-264050-6zpw6itb	58	20	host	host	NN
cord-264050-6zpw6itb	58	21	damage	damage	NN
cord-264050-6zpw6itb	58	22	in	in	IN
cord-264050-6zpw6itb	58	23	the	the	DT
cord-264050-6zpw6itb	58	24	setting	setting	NN
cord-264050-6zpw6itb	58	25	of	of	IN
cord-264050-6zpw6itb	58	26	C.	C.	NNP
cord-264050-6zpw6itb	58	27	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	58	28	infection	infection	NN
cord-264050-6zpw6itb	58	29	.	.	.
cord-264050-6zpw6itb	59	1	Their	-PRON-	PRP$
cord-264050-6zpw6itb	59	2	study	study	NN
cord-264050-6zpw6itb	59	3	was	be	VBD
cord-264050-6zpw6itb	59	4	undertaken	undertake	VBN
cord-264050-6zpw6itb	59	5	to	to	TO
cord-264050-6zpw6itb	59	6	gain	gain	VB
cord-264050-6zpw6itb	59	7	insight	insight	NN
cord-264050-6zpw6itb	59	8	into	into	IN
cord-264050-6zpw6itb	59	9	the	the	DT
cord-264050-6zpw6itb	59	10	role	role	NN
cord-264050-6zpw6itb	59	11	that	that	WDT
cord-264050-6zpw6itb	59	12	CD4	CD4	NNP
cord-264050-6zpw6itb	59	13	ϩ	ϩ	WDT
cord-264050-6zpw6itb	59	14	T	t	NN
cord-264050-6zpw6itb	59	15	cells	cell	NNS
cord-264050-6zpw6itb	59	16	may	may	MD
cord-264050-6zpw6itb	59	17	play	play	VB
cord-264050-6zpw6itb	59	18	in	in	IN
cord-264050-6zpw6itb	59	19	the	the	DT
cord-264050-6zpw6itb	59	20	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	59	21	of	of	IN
cord-264050-6zpw6itb	59	22	IRIS	IRIS	NNP
cord-264050-6zpw6itb	59	23	-	-	,
cord-264050-6zpw6itb	59	24	and	and	CC
cord-264050-6zpw6itb	59	25	postinfectious	postinfectious	JJ
cord-264050-6zpw6itb	59	26	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	59	27	syndromes	syndrome	NNS
cord-264050-6zpw6itb	59	28	(	(	-LRB-
cord-264050-6zpw6itb	59	29	PIIRS	PIIRS	NNP
cord-264050-6zpw6itb	59	30	)	)	-RRB-
cord-264050-6zpw6itb	59	31	in	in	IN
cord-264050-6zpw6itb	59	32	HIVinfected	HIVinfected	NNP
cord-264050-6zpw6itb	59	33	and	and	CC
cord-264050-6zpw6itb	59	34	HIV	HIV	NNP
cord-264050-6zpw6itb	59	35	-	-	HYPH
cord-264050-6zpw6itb	59	36	uninfected	uninfected	JJ
cord-264050-6zpw6itb	59	37	patients	patient	NNS
cord-264050-6zpw6itb	59	38	with	with	IN
cord-264050-6zpw6itb	59	39	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	59	40	.	.	.
cord-264050-6zpw6itb	60	1	Mice	mouse	NNS
cord-264050-6zpw6itb	60	2	infected	infect	VBD
cord-264050-6zpw6itb	60	3	intravenously	intravenously	RB
cord-264050-6zpw6itb	60	4	with	with	IN
cord-264050-6zpw6itb	60	5	10	10	CD
cord-264050-6zpw6itb	60	6	6	6	CD
cord-264050-6zpw6itb	60	7	CFU	CFU	NNP
cord-264050-6zpw6itb	60	8	of	of	IN
cord-264050-6zpw6itb	60	9	C.	C.	NNP
cord-264050-6zpw6itb	60	10	neoformans	neoforman	NNS
cord-264050-6zpw6itb	60	11	were	be	VBD
cord-264050-6zpw6itb	60	12	monitored	monitor	VBN
cord-264050-6zpw6itb	60	13	clinically	clinically	RB
cord-264050-6zpw6itb	60	14	or	or	CC
cord-264050-6zpw6itb	60	15	analyzed	analyze	VBN
cord-264050-6zpw6itb	60	16	to	to	TO
cord-264050-6zpw6itb	60	17	determine	determine	VB
cord-264050-6zpw6itb	60	18	their	-PRON-	PRP$
cord-264050-6zpw6itb	60	19	central	central	JJ
cord-264050-6zpw6itb	60	20	nervous	nervous	JJ
cord-264050-6zpw6itb	60	21	system	system	NN
cord-264050-6zpw6itb	60	22	(	(	-LRB-
cord-264050-6zpw6itb	60	23	CNS	CNS	NNP
cord-264050-6zpw6itb	60	24	)	)	-RRB-
cord-264050-6zpw6itb	60	25	fungal	fungal	JJ
cord-264050-6zpw6itb	60	26	burden	burden	NN
cord-264050-6zpw6itb	60	27	(	(	-LRB-
cord-264050-6zpw6itb	60	28	CFU	CFU	NNP
cord-264050-6zpw6itb	60	29	)	)	-RRB-
cord-264050-6zpw6itb	60	30	,	,	,
cord-264050-6zpw6itb	60	31	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	60	32	pathology	pathology	NN
cord-264050-6zpw6itb	60	33	,	,	,
cord-264050-6zpw6itb	60	34	and	and	CC
cord-264050-6zpw6itb	60	35	cellular	cellular	JJ
cord-264050-6zpw6itb	60	36	and	and	CC
cord-264050-6zpw6itb	60	37	cytokine	cytokine	JJ
cord-264050-6zpw6itb	60	38	responses	response	NNS
cord-264050-6zpw6itb	60	39	.	.	.
cord-264050-6zpw6itb	61	1	The	the	DT
cord-264050-6zpw6itb	61	2	number	number	NN
cord-264050-6zpw6itb	61	3	of	of	IN
cord-264050-6zpw6itb	61	4	C.	C.	NNP
cord-264050-6zpw6itb	61	5	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	61	6	CFU	CFU	NNP
cord-264050-6zpw6itb	61	7	in	in	IN
cord-264050-6zpw6itb	61	8	the	the	DT
cord-264050-6zpw6itb	61	9	brains	brain	NNS
cord-264050-6zpw6itb	61	10	of	of	IN
cord-264050-6zpw6itb	61	11	mice	mouse	NNS
cord-264050-6zpw6itb	61	12	increased	increase	VBD
cord-264050-6zpw6itb	61	13	from	from	IN
cord-264050-6zpw6itb	61	14	1	1	CD
cord-264050-6zpw6itb	61	15	to	to	IN
cord-264050-6zpw6itb	61	16	3	3	CD
cord-264050-6zpw6itb	61	17	weeks	week	NNS
cord-264050-6zpw6itb	61	18	after	after	IN
cord-264050-6zpw6itb	61	19	infection	infection	NN
cord-264050-6zpw6itb	61	20	and	and	CC
cord-264050-6zpw6itb	61	21	then	then	RB
cord-264050-6zpw6itb	61	22	decreased	decrease	VBD
cord-264050-6zpw6itb	61	23	from	from	IN
cord-264050-6zpw6itb	61	24	3	3	CD
cord-264050-6zpw6itb	61	25	to	to	TO
cord-264050-6zpw6itb	61	26	5	5	CD
cord-264050-6zpw6itb	61	27	weeks	week	NNS
cord-264050-6zpw6itb	61	28	thereafter	thereafter	RB
cord-264050-6zpw6itb	61	29	.	.	.
cord-264050-6zpw6itb	62	1	Interestingly	interestingly	RB
cord-264050-6zpw6itb	62	2	,	,	,
cord-264050-6zpw6itb	62	3	the	the	DT
cord-264050-6zpw6itb	62	4	mice	mouse	NNS
cord-264050-6zpw6itb	62	5	developed	develop	VBD
cord-264050-6zpw6itb	62	6	symptomatic	symptomatic	JJ
cord-264050-6zpw6itb	62	7	disease	disease	NN
cord-264050-6zpw6itb	62	8	and	and	CC
cord-264050-6zpw6itb	62	9	neurological	neurological	JJ
cord-264050-6zpw6itb	62	10	deterioration	deterioration	NN
cord-264050-6zpw6itb	62	11	3	3	CD
cord-264050-6zpw6itb	62	12	to	to	TO
cord-264050-6zpw6itb	62	13	4	4	CD
cord-264050-6zpw6itb	62	14	weeks	week	NNS
cord-264050-6zpw6itb	62	15	after	after	IN
cord-264050-6zpw6itb	62	16	infection	infection	NN
cord-264050-6zpw6itb	62	17	,	,	,
cord-264050-6zpw6itb	62	18	corresponding	correspond	VBG
cord-264050-6zpw6itb	62	19	to	to	IN
cord-264050-6zpw6itb	62	20	fungal	fungal	JJ
cord-264050-6zpw6itb	62	21	clearance	clearance	NN
cord-264050-6zpw6itb	62	22	and	and	CC
cord-264050-6zpw6itb	62	23	surprisingly	surprisingly	RB
cord-264050-6zpw6itb	62	24	,	,	,
cord-264050-6zpw6itb	62	25	mortality	mortality	NN
cord-264050-6zpw6itb	62	26	.	.	.
cord-264050-6zpw6itb	63	1	CNS	CNS	NNP
cord-264050-6zpw6itb	63	2	pathology	pathology	NN
cord-264050-6zpw6itb	63	3	revealed	reveal	VBD
cord-264050-6zpw6itb	63	4	cellular	cellular	JJ
cord-264050-6zpw6itb	63	5	inflammation	inflammation	NN
cord-264050-6zpw6itb	63	6	marked	mark	VBN
cord-264050-6zpw6itb	63	7	by	by	IN
cord-264050-6zpw6itb	63	8	leukocytes	leukocyte	NNS
cord-264050-6zpw6itb	63	9	beginning	begin	VBG
cord-264050-6zpw6itb	63	10	3	3	CD
cord-264050-6zpw6itb	63	11	weeks	week	NNS
cord-264050-6zpw6itb	63	12	after	after	IN
cord-264050-6zpw6itb	63	13	infection	infection	NN
cord-264050-6zpw6itb	63	14	that	that	WDT
cord-264050-6zpw6itb	63	15	subsequently	subsequently	RB
cord-264050-6zpw6itb	63	16	increased	increase	VBD
cord-264050-6zpw6itb	63	17	due	due	IN
cord-264050-6zpw6itb	63	18	to	to	IN
cord-264050-6zpw6itb	63	19	infiltration	infiltration	NN
cord-264050-6zpw6itb	63	20	of	of	IN
cord-264050-6zpw6itb	63	21	CD4	CD4	NNP
cord-264050-6zpw6itb	63	22	ϩ	ϩ	NNP
cord-264050-6zpw6itb	63	23	and	and	CC
cord-264050-6zpw6itb	63	24	CD8	CD8	NNP
cord-264050-6zpw6itb	63	25	ϩ	ϩ	NNP
cord-264050-6zpw6itb	63	26	T	T	NNP
cord-264050-6zpw6itb	63	27	cells	cell	NNS
cord-264050-6zpw6itb	63	28	,	,	,
cord-264050-6zpw6itb	63	29	with	with	IN
cord-264050-6zpw6itb	63	30	CD4	CD4	NNP
cord-264050-6zpw6itb	63	31	ϩ	ϩ	NNP
cord-264050-6zpw6itb	63	32	T	t	NN
cord-264050-6zpw6itb	63	33	cells	cell	NNS
cord-264050-6zpw6itb	63	34	being	be	VBG
cord-264050-6zpw6itb	63	35	the	the	DT
cord-264050-6zpw6itb	63	36	predominant	predominant	JJ
cord-264050-6zpw6itb	63	37	population	population	NN
cord-264050-6zpw6itb	63	38	and	and	CC
cord-264050-6zpw6itb	63	39	both	both	DT
cord-264050-6zpw6itb	63	40	populations	population	NNS
cord-264050-6zpw6itb	63	41	being	be	VBG
cord-264050-6zpw6itb	63	42	antigen	antigen	NN
cord-264050-6zpw6itb	63	43	experienced	experience	VBN
cord-264050-6zpw6itb	63	44	.	.	.
cord-264050-6zpw6itb	64	1	Infiltrating	infiltrate	VBG
cord-264050-6zpw6itb	64	2	CD4	CD4	NNP
cord-264050-6zpw6itb	64	3	ϩ	ϩ	NNP
cord-264050-6zpw6itb	64	4	and	and	CC
cord-264050-6zpw6itb	64	5	CD8	CD8	NNP
cord-264050-6zpw6itb	64	6	ϩ	ϩ	NNP
cord-264050-6zpw6itb	64	7	T	T	NNP
cord-264050-6zpw6itb	64	8	cells	cell	NNS
cord-264050-6zpw6itb	64	9	exhibited	exhibit	VBD
cord-264050-6zpw6itb	64	10	a	a	DT
cord-264050-6zpw6itb	64	11	Th1-type	Th1-type	NNP
cord-264050-6zpw6itb	64	12	bias	bias	NN
cord-264050-6zpw6itb	64	13	,	,	,
cord-264050-6zpw6itb	64	14	producing	produce	VBG
cord-264050-6zpw6itb	64	15	IFN-	IFN-	NNP
cord-264050-6zpw6itb	64	16	␥	␥	XX
cord-264050-6zpw6itb	64	17	.	.	.
cord-264050-6zpw6itb	65	1	Depletion	depletion	NN
cord-264050-6zpw6itb	65	2	of	of	IN
cord-264050-6zpw6itb	65	3	CD4	CD4	NNP
cord-264050-6zpw6itb	65	4	ϩ	ϩ	NNP
cord-264050-6zpw6itb	65	5	T	t	NN
cord-264050-6zpw6itb	65	6	cells	cell	NNS
cord-264050-6zpw6itb	65	7	resulted	result	VBD
cord-264050-6zpw6itb	65	8	in	in	IN
cord-264050-6zpw6itb	65	9	reduced	reduce	VBN
cord-264050-6zpw6itb	65	10	mortality	mortality	NN
cord-264050-6zpw6itb	65	11	and	and	CC
cord-264050-6zpw6itb	65	12	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	65	13	pathology	pathology	NN
cord-264050-6zpw6itb	65	14	,	,	,
cord-264050-6zpw6itb	65	15	providing	provide	VBG
cord-264050-6zpw6itb	65	16	proof	proof	NN
cord-264050-6zpw6itb	65	17	of	of	IN
cord-264050-6zpw6itb	65	18	concept	concept	NN
cord-264050-6zpw6itb	65	19	that	that	WDT
cord-264050-6zpw6itb	65	20	CD4	CD4	NNP
cord-264050-6zpw6itb	65	21	ϩ	ϩ	WDT
cord-264050-6zpw6itb	65	22	Outcomes	Outcomes	NNP
cord-264050-6zpw6itb	65	23	of	of	IN
cord-264050-6zpw6itb	65	24	host	host	NN
cord-264050-6zpw6itb	65	25	-	-	:
cord-264050-6zpw6itb	65	26	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	65	27	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	65	28	interaction	interaction	NN
cord-264050-6zpw6itb	65	29	depicted	depict	VBN
cord-264050-6zpw6itb	65	30	by	by	IN
cord-264050-6zpw6itb	65	31	the	the	DT
cord-264050-6zpw6itb	65	32	basic	basic	JJ
cord-264050-6zpw6itb	65	33	parabola	parabola	NN
cord-264050-6zpw6itb	65	34	of	of	IN
cord-264050-6zpw6itb	65	35	the	the	DT
cord-264050-6zpw6itb	65	36	damage	damage	NN
cord-264050-6zpw6itb	65	37	-	-	HYPH
cord-264050-6zpw6itb	65	38	response	response	NN
cord-264050-6zpw6itb	65	39	framework	framework	NN
cord-264050-6zpw6itb	65	40	.	.	.
cord-264050-6zpw6itb	66	1	The	the	DT
cord-264050-6zpw6itb	66	2	left	left	JJ
cord-264050-6zpw6itb	66	3	side	side	NN
cord-264050-6zpw6itb	66	4	of	of	IN
cord-264050-6zpw6itb	66	5	the	the	DT
cord-264050-6zpw6itb	66	6	parabola	parabola	NN
cord-264050-6zpw6itb	66	7	,	,	,
cord-264050-6zpw6itb	66	8	shaded	shade	VBN
cord-264050-6zpw6itb	66	9	in	in	IN
cord-264050-6zpw6itb	66	10	green	green	JJ
cord-264050-6zpw6itb	66	11	and	and	CC
cord-264050-6zpw6itb	66	12	labeled	label	VBN
cord-264050-6zpw6itb	66	13	weak	weak	JJ
cord-264050-6zpw6itb	66	14	,	,	,
cord-264050-6zpw6itb	66	15	depicts	depict	VBZ
cord-264050-6zpw6itb	66	16	the	the	DT
cord-264050-6zpw6itb	66	17	original	original	JJ
cord-264050-6zpw6itb	66	18	circa	circa	NN
cord-264050-6zpw6itb	66	19	1999	1999	CD
cord-264050-6zpw6itb	66	20	concept	concept	NN
cord-264050-6zpw6itb	66	21	that	that	WDT
cord-264050-6zpw6itb	66	22	C.	C.	NNP
cord-264050-6zpw6itb	66	23	neoformans	neoformans	NNP
cord-264050-6zpw6itb	66	24	was	be	VBD
cord-264050-6zpw6itb	66	25	a	a	DT
cord-264050-6zpw6itb	66	26	class	class	NN
cord-264050-6zpw6itb	66	27	2	2	CD
cord-264050-6zpw6itb	66	28	pathogen	pathogen	NN
cord-264050-6zpw6itb	66	29	that	that	WDT
cord-264050-6zpw6itb	66	30	caused	cause	VBD
cord-264050-6zpw6itb	66	31	damage	damage	NN
cord-264050-6zpw6itb	66	32	in	in	IN
cord-264050-6zpw6itb	66	33	the	the	DT
cord-264050-6zpw6itb	66	34	setting	setting	NN
cord-264050-6zpw6itb	66	35	of	of	IN
cord-264050-6zpw6itb	66	36	a	a	DT
cord-264050-6zpw6itb	66	37	weak	weak	JJ
cord-264050-6zpw6itb	66	38	or	or	CC
cord-264050-6zpw6itb	66	39	normal	normal	JJ
cord-264050-6zpw6itb	66	40	immune	immune	JJ
cord-264050-6zpw6itb	66	41	response	response	NN
cord-264050-6zpw6itb	66	42	.	.	.
cord-264050-6zpw6itb	67	1	Here	here	RB
cord-264050-6zpw6itb	67	2	,	,	,
cord-264050-6zpw6itb	67	3	the	the	DT
cord-264050-6zpw6itb	67	4	immune	immune	JJ
cord-264050-6zpw6itb	67	5	response	response	NN
cord-264050-6zpw6itb	67	6	fails	fail	VBZ
cord-264050-6zpw6itb	67	7	to	to	TO
cord-264050-6zpw6itb	67	8	limit	limit	VB
cord-264050-6zpw6itb	67	9	fungal	fungal	JJ
cord-264050-6zpw6itb	67	10	growth	growth	NN
cord-264050-6zpw6itb	67	11	,	,	,
cord-264050-6zpw6itb	67	12	which	which	WDT
cord-264050-6zpw6itb	67	13	results	result	VBZ
cord-264050-6zpw6itb	67	14	in	in	IN
cord-264050-6zpw6itb	67	15	host	host	NN
cord-264050-6zpw6itb	67	16	damage	damage	NN
cord-264050-6zpw6itb	67	17	.	.	.
cord-264050-6zpw6itb	68	1	The	the	DT
cord-264050-6zpw6itb	68	2	right	right	JJ
cord-264050-6zpw6itb	68	3	side	side	NN
cord-264050-6zpw6itb	68	4	of	of	IN
cord-264050-6zpw6itb	68	5	the	the	DT
cord-264050-6zpw6itb	68	6	parabola	parabola	NN
cord-264050-6zpw6itb	68	7	,	,	,
cord-264050-6zpw6itb	68	8	shaded	shade	VBN
cord-264050-6zpw6itb	68	9	in	in	IN
cord-264050-6zpw6itb	68	10	red	red	JJ
cord-264050-6zpw6itb	68	11	and	and	CC
cord-264050-6zpw6itb	68	12	labeled	label	VBN
cord-264050-6zpw6itb	68	13	strong	strong	JJ
cord-264050-6zpw6itb	68	14	,	,	,
cord-264050-6zpw6itb	68	15	depicts	depict	VBZ
cord-264050-6zpw6itb	68	16	information	information	NN
cord-264050-6zpw6itb	68	17	that	that	WDT
cord-264050-6zpw6itb	68	18	has	have	VBZ
cord-264050-6zpw6itb	68	19	emerged	emerge	VBN
cord-264050-6zpw6itb	68	20	since	since	IN
cord-264050-6zpw6itb	68	21	1999	1999	CD
cord-264050-6zpw6itb	68	22	,	,	,
cord-264050-6zpw6itb	68	23	which	which	WDT
cord-264050-6zpw6itb	68	24	has	have	VBZ
cord-264050-6zpw6itb	68	25	revealed	reveal	VBN
cord-264050-6zpw6itb	68	26	that	that	IN
cord-264050-6zpw6itb	68	27	C.	C.	NNP
cord-264050-6zpw6itb	68	28	neoformans	neoforman	NNS
cord-264050-6zpw6itb	68	29	can	can	MD
cord-264050-6zpw6itb	68	30	elicit	elicit	VB
cord-264050-6zpw6itb	68	31	strong	strong	JJ
cord-264050-6zpw6itb	68	32	immune	immune	JJ
cord-264050-6zpw6itb	68	33	responses	response	NNS
cord-264050-6zpw6itb	68	34	that	that	WDT
cord-264050-6zpw6itb	68	35	produce	produce	VBP
cord-264050-6zpw6itb	68	36	host	host	NN
cord-264050-6zpw6itb	68	37	damage	damage	NN
cord-264050-6zpw6itb	68	38	stemming	stem	VBG
cord-264050-6zpw6itb	68	39	from	from	IN
cord-264050-6zpw6itb	68	40	inflammation	inflammation	NN
cord-264050-6zpw6itb	68	41	.	.	.
cord-264050-6zpw6itb	69	1	The	the	DT
cord-264050-6zpw6itb	69	2	portion	portion	NN
cord-264050-6zpw6itb	69	3	of	of	IN
cord-264050-6zpw6itb	69	4	the	the	DT
cord-264050-6zpw6itb	69	5	parabola	parabola	NN
cord-264050-6zpw6itb	69	6	that	that	WDT
cord-264050-6zpw6itb	69	7	rises	rise	VBZ
cord-264050-6zpw6itb	69	8	above	above	IN
cord-264050-6zpw6itb	69	9	the	the	DT
cord-264050-6zpw6itb	69	10	black	black	JJ
cord-264050-6zpw6itb	69	11	dotted	dotted	JJ
cord-264050-6zpw6itb	69	12	line	line	NN
cord-264050-6zpw6itb	69	13	represents	represent	VBZ
cord-264050-6zpw6itb	69	14	the	the	DT
cord-264050-6zpw6itb	69	15	threshold	threshold	NN
cord-264050-6zpw6itb	69	16	for	for	IN
cord-264050-6zpw6itb	69	17	clinical	clinical	JJ
cord-264050-6zpw6itb	69	18	disease	disease	NN
cord-264050-6zpw6itb	69	19	.	.	.
cord-264050-6zpw6itb	70	1	The	the	DT
cord-264050-6zpw6itb	70	2	portion	portion	NN
cord-264050-6zpw6itb	70	3	of	of	IN
cord-264050-6zpw6itb	70	4	the	the	DT
cord-264050-6zpw6itb	70	5	parabola	parabola	NN
cord-264050-6zpw6itb	70	6	that	that	WDT
cord-264050-6zpw6itb	70	7	lies	lie	VBZ
cord-264050-6zpw6itb	70	8	below	below	IN
cord-264050-6zpw6itb	70	9	the	the	DT
cord-264050-6zpw6itb	70	10	black	black	JJ
cord-264050-6zpw6itb	70	11	dotted	dotted	JJ
cord-264050-6zpw6itb	70	12	line	line	NN
cord-264050-6zpw6itb	70	13	represents	represent	VBZ
cord-264050-6zpw6itb	70	14	the	the	DT
cord-264050-6zpw6itb	70	15	state	state	NN
cord-264050-6zpw6itb	70	16	of	of	IN
cord-264050-6zpw6itb	70	17	C.	C.	NNP
cord-264050-6zpw6itb	70	18	neoformans	neoformans	NNP
cord-264050-6zpw6itb	70	19	latency	latency	NNP
cord-264050-6zpw6itb	70	20	,	,	,
cord-264050-6zpw6itb	70	21	which	which	WDT
cord-264050-6zpw6itb	70	22	is	be	VBZ
cord-264050-6zpw6itb	70	23	not	not	RB
cord-264050-6zpw6itb	70	24	associated	associate	VBN
cord-264050-6zpw6itb	70	25	with	with	IN
cord-264050-6zpw6itb	70	26	clinically	clinically	RB
cord-264050-6zpw6itb	70	27	evident	evident	JJ
cord-264050-6zpw6itb	70	28	host	host	NN
cord-264050-6zpw6itb	70	29	damage	damage	NN
cord-264050-6zpw6itb	70	30	.	.	.
cord-264050-6zpw6itb	71	1	Proposed	propose	VBN
cord-264050-6zpw6itb	71	2	therapeutic	therapeutic	JJ
cord-264050-6zpw6itb	71	3	interventions	intervention	NNS
cord-264050-6zpw6itb	71	4	,	,	,
cord-264050-6zpw6itb	71	5	based	base	VBN
cord-264050-6zpw6itb	71	6	on	on	IN
cord-264050-6zpw6itb	71	7	counteracting	counteract	VBG
cord-264050-6zpw6itb	71	8	the	the	DT
cord-264050-6zpw6itb	71	9	main	main	JJ
cord-264050-6zpw6itb	71	10	source	source	NN
cord-264050-6zpw6itb	71	11	of	of	IN
cord-264050-6zpw6itb	71	12	host	host	NN
cord-264050-6zpw6itb	71	13	damage	damage	NN
cord-264050-6zpw6itb	71	14	are	be	VBP
cord-264050-6zpw6itb	71	15	depicted	depict	VBN
cord-264050-6zpw6itb	71	16	by	by	IN
cord-264050-6zpw6itb	71	17	red	red	NN
cord-264050-6zpw6itb	71	18	(	(	-LRB-
cord-264050-6zpw6itb	71	19	to	to	TO
cord-264050-6zpw6itb	71	20	enhance	enhance	VB
cord-264050-6zpw6itb	71	21	weak	weak	JJ
cord-264050-6zpw6itb	71	22	response	response	NN
cord-264050-6zpw6itb	71	23	)	)	-RRB-
cord-264050-6zpw6itb	71	24	or	or	CC
cord-264050-6zpw6itb	71	25	green	green	JJ
cord-264050-6zpw6itb	71	26	(	(	-LRB-
cord-264050-6zpw6itb	71	27	to	to	TO
cord-264050-6zpw6itb	71	28	reduce	reduce	VB
cord-264050-6zpw6itb	71	29	strong	strong	JJ
cord-264050-6zpw6itb	71	30	response	response	NN
cord-264050-6zpw6itb	71	31	)	)	-RRB-
cord-264050-6zpw6itb	71	32	arrows	arrow	NNS
cord-264050-6zpw6itb	71	33	.	.	.
cord-264050-6zpw6itb	72	1	Some	some	DT
cord-264050-6zpw6itb	72	2	factors	factor	NNS
cord-264050-6zpw6itb	72	3	that	that	WDT
cord-264050-6zpw6itb	72	4	contribute	contribute	VBP
cord-264050-6zpw6itb	72	5	to	to	IN
cord-264050-6zpw6itb	72	6	weak	weak	JJ
cord-264050-6zpw6itb	72	7	and	and	CC
cord-264050-6zpw6itb	72	8	strong	strong	JJ
cord-264050-6zpw6itb	72	9	immune	immune	JJ
cord-264050-6zpw6itb	72	10	responses	response	NNS
cord-264050-6zpw6itb	72	11	are	be	VBP
cord-264050-6zpw6itb	72	12	shown	show	VBN
cord-264050-6zpw6itb	72	13	along	along	IN
cord-264050-6zpw6itb	72	14	the	the	DT
cord-264050-6zpw6itb	72	15	y	y	NNP
cord-264050-6zpw6itb	72	16	axis	axis	NN
cord-264050-6zpw6itb	72	17	for	for	IN
cord-264050-6zpw6itb	72	18	each	each	DT
cord-264050-6zpw6itb	72	19	type	type	NN
cord-264050-6zpw6itb	72	20	of	of	IN
cord-264050-6zpw6itb	72	21	response	response	NN
cord-264050-6zpw6itb	72	22	,	,	,
cord-264050-6zpw6itb	72	23	though	though	IN
cord-264050-6zpw6itb	72	24	immunity	immunity	NN
cord-264050-6zpw6itb	72	25	is	be	VBZ
cord-264050-6zpw6itb	72	26	likely	likely	RB
cord-264050-6zpw6itb	72	27	multifactorial	multifactorial	JJ
cord-264050-6zpw6itb	72	28	,	,	,
cord-264050-6zpw6itb	72	29	and	and	CC
cord-264050-6zpw6itb	72	30	additional	additional	JJ
cord-264050-6zpw6itb	72	31	factors	factor	NNS
cord-264050-6zpw6itb	72	32	are	be	VBP
cord-264050-6zpw6itb	72	33	also	also	RB
cord-264050-6zpw6itb	72	34	likely	likely	JJ
cord-264050-6zpw6itb	72	35	to	to	TO
cord-264050-6zpw6itb	72	36	contribute	contribute	VB
cord-264050-6zpw6itb	72	37	(	(	-LRB-
cord-264050-6zpw6itb	72	38	16	16	CD
cord-264050-6zpw6itb	72	39	,	,	,
cord-264050-6zpw6itb	72	40	29	29	CD
cord-264050-6zpw6itb	72	41	-35	-35	CD
cord-264050-6zpw6itb	72	42	)	)	-RRB-
cord-264050-6zpw6itb	72	43	.	.	.
cord-264050-6zpw6itb	73	1	Commentary	commentary	NN
cord-264050-6zpw6itb	73	2	®	®	POS
cord-264050-6zpw6itb	73	3	T	T	NNP
cord-264050-6zpw6itb	73	4	cells	cell	NNS
cord-264050-6zpw6itb	73	5	were	be	VBD
cord-264050-6zpw6itb	73	6	the	the	DT
cord-264050-6zpw6itb	73	7	principal	principal	JJ
cord-264050-6zpw6itb	73	8	mediators	mediator	NNS
cord-264050-6zpw6itb	73	9	of	of	IN
cord-264050-6zpw6itb	73	10	inflammation	inflammation	NN
cord-264050-6zpw6itb	73	11	and	and	CC
cord-264050-6zpw6itb	73	12	damage	damage	NN
cord-264050-6zpw6itb	73	13	in	in	IN
cord-264050-6zpw6itb	73	14	this	this	DT
cord-264050-6zpw6itb	73	15	model	model	NN
cord-264050-6zpw6itb	73	16	.	.	.
cord-264050-6zpw6itb	74	1	Notably	notably	RB
cord-264050-6zpw6itb	74	2	,	,	,
cord-264050-6zpw6itb	74	3	survival	survival	NN
cord-264050-6zpw6itb	74	4	of	of	IN
cord-264050-6zpw6itb	74	5	infected	infect	VBN
cord-264050-6zpw6itb	74	6	,	,	,
cord-264050-6zpw6itb	74	7	CD4	CD4	NNP
cord-264050-6zpw6itb	74	8	ϩ	ϩ	NN
cord-264050-6zpw6itb	74	9	T	T	NNP
cord-264050-6zpw6itb	74	10	cell	cell	NN
cord-264050-6zpw6itb	74	11	-	-	HYPH
cord-264050-6zpw6itb	74	12	depleted	deplete	VBN
cord-264050-6zpw6itb	74	13	mice	mouse	NNS
cord-264050-6zpw6itb	74	14	was	be	VBD
cord-264050-6zpw6itb	74	15	improved	improve	VBN
cord-264050-6zpw6itb	74	16	despite	despite	IN
cord-264050-6zpw6itb	74	17	an	an	DT
cord-264050-6zpw6itb	74	18	inability	inability	NN
cord-264050-6zpw6itb	74	19	to	to	TO
cord-264050-6zpw6itb	74	20	induce	induce	VB
cord-264050-6zpw6itb	74	21	fungal	fungal	JJ
cord-264050-6zpw6itb	74	22	clearance	clearance	NN
cord-264050-6zpw6itb	74	23	and	and	CC
cord-264050-6zpw6itb	74	24	markedly	markedly	RB
cord-264050-6zpw6itb	74	25	elevated	elevated	JJ
cord-264050-6zpw6itb	74	26	fungal	fungal	JJ
cord-264050-6zpw6itb	74	27	burdens	burden	NNS
cord-264050-6zpw6itb	74	28	compared	compare	VBN
cord-264050-6zpw6itb	74	29	to	to	IN
cord-264050-6zpw6itb	74	30	mice	mouse	NNS
cord-264050-6zpw6itb	74	31	with	with	IN
cord-264050-6zpw6itb	74	32	sufficient	sufficient	JJ
cord-264050-6zpw6itb	74	33	CD4	CD4	NNP
cord-264050-6zpw6itb	74	34	ϩ	ϩ	NNP
cord-264050-6zpw6itb	74	35	T	t	NN
cord-264050-6zpw6itb	74	36	cells	cell	NNS
cord-264050-6zpw6itb	74	37	.	.	.
cord-264050-6zpw6itb	75	1	The	the	DT
cord-264050-6zpw6itb	75	2	data	datum	NNS
cord-264050-6zpw6itb	75	3	generated	generate	VBN
cord-264050-6zpw6itb	75	4	by	by	IN
cord-264050-6zpw6itb	75	5	Neal	Neal	NNP
cord-264050-6zpw6itb	75	6	et	et	NNP
cord-264050-6zpw6itb	75	7	al	al	NNP
cord-264050-6zpw6itb	75	8	.	.	.
cord-264050-6zpw6itb	76	1	(	(	-LRB-
cord-264050-6zpw6itb	76	2	2	2	LS
cord-264050-6zpw6itb	76	3	)	)	-RRB-
cord-264050-6zpw6itb	76	4	demonstrate	demonstrate	VBP
cord-264050-6zpw6itb	76	5	that	that	IN
cord-264050-6zpw6itb	76	6	CD4	CD4	NNP
cord-264050-6zpw6itb	76	7	ϩ	ϩ	WDT
cord-264050-6zpw6itb	76	8	T	t	NN
cord-264050-6zpw6itb	76	9	cells	cell	NNS
cord-264050-6zpw6itb	76	10	can	can	MD
cord-264050-6zpw6itb	76	11	play	play	VB
cord-264050-6zpw6itb	76	12	dichotomous	dichotomous	JJ
cord-264050-6zpw6itb	76	13	roles	role	NNS
cord-264050-6zpw6itb	76	14	in	in	IN
cord-264050-6zpw6itb	76	15	C.	C.	NNP
cord-264050-6zpw6itb	76	16	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	76	17	infection	infection	NN
cord-264050-6zpw6itb	76	18	.	.	.
cord-264050-6zpw6itb	77	1	On	on	IN
cord-264050-6zpw6itb	77	2	one	one	CD
cord-264050-6zpw6itb	77	3	hand	hand	NN
cord-264050-6zpw6itb	77	4	,	,	,
cord-264050-6zpw6itb	77	5	they	-PRON-	PRP
cord-264050-6zpw6itb	77	6	can	can	MD
cord-264050-6zpw6itb	77	7	mediate	mediate	VB
cord-264050-6zpw6itb	77	8	fungal	fungal	JJ
cord-264050-6zpw6itb	77	9	clearance	clearance	NN
cord-264050-6zpw6itb	77	10	in	in	IN
cord-264050-6zpw6itb	77	11	the	the	DT
cord-264050-6zpw6itb	77	12	CNS	CNS	NNP
cord-264050-6zpw6itb	77	13	,	,	,
cord-264050-6zpw6itb	77	14	but	but	CC
cord-264050-6zpw6itb	77	15	on	on	IN
cord-264050-6zpw6itb	77	16	the	the	DT
cord-264050-6zpw6itb	77	17	other	other	JJ
cord-264050-6zpw6itb	77	18	hand	hand	NN
cord-264050-6zpw6itb	77	19	,	,	,
cord-264050-6zpw6itb	77	20	they	-PRON-	PRP
cord-264050-6zpw6itb	77	21	can	can	MD
cord-264050-6zpw6itb	77	22	induce	induce	VB
cord-264050-6zpw6itb	77	23	inflammation	inflammation	NN
cord-264050-6zpw6itb	77	24	that	that	WDT
cord-264050-6zpw6itb	77	25	leads	lead	VBZ
cord-264050-6zpw6itb	77	26	to	to	IN
cord-264050-6zpw6itb	77	27	neurological	neurological	JJ
cord-264050-6zpw6itb	77	28	deterioration	deterioration	NN
cord-264050-6zpw6itb	77	29	and	and	CC
cord-264050-6zpw6itb	77	30	death	death	NN
cord-264050-6zpw6itb	77	31	.	.	.
cord-264050-6zpw6itb	78	1	This	this	DT
cord-264050-6zpw6itb	78	2	suggests	suggest	VBZ
cord-264050-6zpw6itb	78	3	a	a	DT
cord-264050-6zpw6itb	78	4	possible	possible	JJ
cord-264050-6zpw6itb	78	5	explanation	explanation	NN
cord-264050-6zpw6itb	78	6	for	for	IN
cord-264050-6zpw6itb	78	7	why	why	WRB
cord-264050-6zpw6itb	78	8	inflammation	inflammation	NN
cord-264050-6zpw6itb	78	9	is	be	VBZ
cord-264050-6zpw6itb	78	10	often	often	RB
cord-264050-6zpw6itb	78	11	a	a	DT
cord-264050-6zpw6itb	78	12	prominent	prominent	JJ
cord-264050-6zpw6itb	78	13	feature	feature	NN
cord-264050-6zpw6itb	78	14	of	of	IN
cord-264050-6zpw6itb	78	15	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	78	16	meningitis	meningitis	NN
cord-264050-6zpw6itb	78	17	in	in	IN
cord-264050-6zpw6itb	78	18	HIV	HIV	NNP
cord-264050-6zpw6itb	78	19	-	-	HYPH
cord-264050-6zpw6itb	78	20	uninfected	uninfected	JJ
cord-264050-6zpw6itb	78	21	,	,	,
cord-264050-6zpw6itb	78	22	but	but	CC
cord-264050-6zpw6itb	78	23	not	not	RB
cord-264050-6zpw6itb	78	24	HIV	HIV	NNP
cord-264050-6zpw6itb	78	25	-	-	HYPH
cord-264050-6zpw6itb	78	26	infected	infect	VBN
cord-264050-6zpw6itb	78	27	patients	patient	NNS
cord-264050-6zpw6itb	78	28	,	,	,
cord-264050-6zpw6itb	78	29	and	and	CC
cord-264050-6zpw6itb	78	30	raises	raise	VBZ
cord-264050-6zpw6itb	78	31	the	the	DT
cord-264050-6zpw6itb	78	32	intriguing	intriguing	JJ
cord-264050-6zpw6itb	78	33	possibility	possibility	NN
cord-264050-6zpw6itb	78	34	that	that	IN
cord-264050-6zpw6itb	78	35	the	the	DT
cord-264050-6zpw6itb	78	36	profound	profound	JJ
cord-264050-6zpw6itb	78	37	CD4	CD4	NNP
cord-264050-6zpw6itb	78	38	ϩ	ϩ	NNP
cord-264050-6zpw6itb	78	39	T	t	NN
cord-264050-6zpw6itb	78	40	cell	cell	NN
cord-264050-6zpw6itb	78	41	deficiency	deficiency	NN
cord-264050-6zpw6itb	78	42	,	,	,
cord-264050-6zpw6itb	78	43	which	which	WDT
cord-264050-6zpw6itb	78	44	portends	portend	VBZ
cord-264050-6zpw6itb	78	45	risk	risk	NN
cord-264050-6zpw6itb	78	46	for	for	IN
cord-264050-6zpw6itb	78	47	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	78	48	,	,	,
cord-264050-6zpw6itb	78	49	may	may	MD
cord-264050-6zpw6itb	78	50	actually	actually	RB
cord-264050-6zpw6itb	78	51	limit	limit	VB
cord-264050-6zpw6itb	78	52	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	78	53	pathology	pathology	NN
cord-264050-6zpw6itb	78	54	in	in	IN
cord-264050-6zpw6itb	78	55	HIV	HIV	NNP
cord-264050-6zpw6itb	78	56	-	-	HYPH
cord-264050-6zpw6itb	78	57	infected	infect	VBN
cord-264050-6zpw6itb	78	58	persons	person	NNS
cord-264050-6zpw6itb	78	59	not	not	RB
cord-264050-6zpw6itb	78	60	on	on	IN
cord-264050-6zpw6itb	78	61	ART	art	NN
cord-264050-6zpw6itb	78	62	.	.	.
cord-264050-6zpw6itb	79	1	This	this	DT
cord-264050-6zpw6itb	79	2	dichotomy	dichotomy	NN
cord-264050-6zpw6itb	79	3	may	may	MD
cord-264050-6zpw6itb	79	4	also	also	RB
cord-264050-6zpw6itb	79	5	provide	provide	VB
cord-264050-6zpw6itb	79	6	insight	insight	NN
cord-264050-6zpw6itb	79	7	into	into	IN
cord-264050-6zpw6itb	79	8	the	the	DT
cord-264050-6zpw6itb	79	9	failure	failure	NN
cord-264050-6zpw6itb	79	10	of	of	IN
cord-264050-6zpw6itb	79	11	adjunctive	adjunctive	JJ
cord-264050-6zpw6itb	79	12	steroid	steroid	NN
cord-264050-6zpw6itb	79	13	therapy	therapy	NN
cord-264050-6zpw6itb	79	14	to	to	TO
cord-264050-6zpw6itb	79	15	reduce	reduce	VB
cord-264050-6zpw6itb	79	16	mortality	mortality	NN
cord-264050-6zpw6itb	79	17	or	or	CC
cord-264050-6zpw6itb	79	18	improve	improve	VB
cord-264050-6zpw6itb	79	19	morbidity	morbidity	NN
cord-264050-6zpw6itb	79	20	in	in	IN
cord-264050-6zpw6itb	79	21	HIV	HIV	NNP
cord-264050-6zpw6itb	79	22	-	-	HYPH
cord-264050-6zpw6itb	79	23	associated	associate	VBN
cord-264050-6zpw6itb	79	24	cryptococcosis	cryptococcosis	NNP
cord-264050-6zpw6itb	79	25	(	(	-LRB-
cord-264050-6zpw6itb	79	26	19	19	CD
cord-264050-6zpw6itb	79	27	)	)	-RRB-
cord-264050-6zpw6itb	79	28	and	and	CC
cord-264050-6zpw6itb	79	29	the	the	DT
cord-264050-6zpw6itb	79	30	fact	fact	NN
cord-264050-6zpw6itb	79	31	that	that	IN
cord-264050-6zpw6itb	79	32	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	79	33	may	may	MD
cord-264050-6zpw6itb	79	34	have	have	VB
cord-264050-6zpw6itb	79	35	a	a	DT
cord-264050-6zpw6itb	79	36	better	well	JJR
cord-264050-6zpw6itb	79	37	prognosis	prognosis	NN
cord-264050-6zpw6itb	79	38	in	in	IN
cord-264050-6zpw6itb	79	39	immunosuppressed	immunosuppressed	JJ
cord-264050-6zpw6itb	79	40	patients	patient	NNS
cord-264050-6zpw6itb	79	41	than	than	IN
cord-264050-6zpw6itb	79	42	in	in	IN
cord-264050-6zpw6itb	79	43	nonimmunosuppressed	nonimmunosuppressed	JJ
cord-264050-6zpw6itb	79	44	patients	patient	NNS
cord-264050-6zpw6itb	79	45	(	(	-LRB-
cord-264050-6zpw6itb	79	46	20	20	CD
cord-264050-6zpw6itb	79	47	)	)	-RRB-
cord-264050-6zpw6itb	79	48	(	(	-LRB-
cord-264050-6zpw6itb	79	49	21	21	CD
cord-264050-6zpw6itb	79	50	)	)	-RRB-
cord-264050-6zpw6itb	79	51	(	(	-LRB-
cord-264050-6zpw6itb	79	52	22	22	CD
cord-264050-6zpw6itb	79	53	)	)	-RRB-
cord-264050-6zpw6itb	79	54	.	.	.
cord-264050-6zpw6itb	80	1	The	the	DT
cord-264050-6zpw6itb	80	2	detrimental	detrimental	JJ
cord-264050-6zpw6itb	80	3	effect	effect	NN
cord-264050-6zpw6itb	80	4	of	of	IN
cord-264050-6zpw6itb	80	5	activated	activate	VBN
cord-264050-6zpw6itb	80	6	CD4	CD4	NNP
cord-264050-6zpw6itb	80	7	ϩ	ϩ	NNP
cord-264050-6zpw6itb	80	8	T	t	NN
cord-264050-6zpw6itb	80	9	cells	cell	NNS
cord-264050-6zpw6itb	80	10	in	in	IN
cord-264050-6zpw6itb	80	11	mice	mouse	NNS
cord-264050-6zpw6itb	80	12	also	also	RB
cord-264050-6zpw6itb	80	13	suggests	suggest	VBZ
cord-264050-6zpw6itb	80	14	the	the	DT
cord-264050-6zpw6itb	80	15	possibility	possibility	NN
cord-264050-6zpw6itb	80	16	that	that	IN
cord-264050-6zpw6itb	80	17	antifungal	antifungal	NN
cord-264050-6zpw6itb	80	18	therapy	therapy	NN
cord-264050-6zpw6itb	80	19	-	-	HYPH
cord-264050-6zpw6itb	80	20	induced	induce	VBN
cord-264050-6zpw6itb	80	21	fungal	fungal	JJ
cord-264050-6zpw6itb	80	22	clearance	clearance	NN
cord-264050-6zpw6itb	80	23	and	and	CC
cord-264050-6zpw6itb	80	24	reduced	reduced	JJ
cord-264050-6zpw6itb	80	25	levels	level	NNS
cord-264050-6zpw6itb	80	26	of	of	IN
cord-264050-6zpw6itb	80	27	glucuronoxylomannan	glucuronoxylomannan	NNP
cord-264050-6zpw6itb	80	28	(	(	-LRB-
cord-264050-6zpw6itb	80	29	GXM	GXM	NNP
cord-264050-6zpw6itb	80	30	)	)	-RRB-
cord-264050-6zpw6itb	80	31	(	(	-LRB-
cord-264050-6zpw6itb	80	32	an	an	DT
cord-264050-6zpw6itb	80	33	immune	immune	JJ
cord-264050-6zpw6itb	80	34	suppressing	suppress	VBG
cord-264050-6zpw6itb	80	35	molecule	molecule	NN
cord-264050-6zpw6itb	80	36	[	[	-LRB-
cord-264050-6zpw6itb	80	37	23	23	CD
cord-264050-6zpw6itb	80	38	]	]	-RRB-
cord-264050-6zpw6itb	81	1	[	[	-LRB-
cord-264050-6zpw6itb	81	2	24	24	CD
cord-264050-6zpw6itb	81	3	]	]	-RRB-
cord-264050-6zpw6itb	81	4	[	[	-LRB-
cord-264050-6zpw6itb	81	5	25	25	CD
cord-264050-6zpw6itb	81	6	]	]	-RRB-
cord-264050-6zpw6itb	81	7	)	)	-RRB-
cord-264050-6zpw6itb	81	8	,	,	,
cord-264050-6zpw6itb	81	9	could	could	MD
cord-264050-6zpw6itb	81	10	enhance	enhance	VB
cord-264050-6zpw6itb	81	11	CD4	CD4	NNP
cord-264050-6zpw6itb	81	12	ϩ	ϩ	NNP
cord-264050-6zpw6itb	81	13	T	T	NNP
cord-264050-6zpw6itb	81	14	cell	cell	NN
cord-264050-6zpw6itb	81	15	activation	activation	NN
cord-264050-6zpw6itb	81	16	and	and	CC
cord-264050-6zpw6itb	81	17	damage	damage	NN
cord-264050-6zpw6itb	81	18	.	.	.
cord-264050-6zpw6itb	82	1	This	this	DT
cord-264050-6zpw6itb	82	2	may	may	MD
cord-264050-6zpw6itb	82	3	help	help	VB
cord-264050-6zpw6itb	82	4	explain	explain	VB
cord-264050-6zpw6itb	82	5	paradoxical	paradoxical	JJ
cord-264050-6zpw6itb	82	6	worsening	worsening	NN
cord-264050-6zpw6itb	82	7	of	of	IN
cord-264050-6zpw6itb	82	8	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	82	9	in	in	IN
cord-264050-6zpw6itb	82	10	certain	certain	JJ
cord-264050-6zpw6itb	82	11	patients	patient	NNS
cord-264050-6zpw6itb	82	12	after	after	IN
cord-264050-6zpw6itb	82	13	initiation	initiation	NN
cord-264050-6zpw6itb	82	14	of	of	IN
cord-264050-6zpw6itb	82	15	antifungal	antifungal	JJ
cord-264050-6zpw6itb	82	16	therapy	therapy	NN
cord-264050-6zpw6itb	82	17	(	(	-LRB-
cord-264050-6zpw6itb	82	18	26	26	CD
cord-264050-6zpw6itb	82	19	)	)	-RRB-
cord-264050-6zpw6itb	82	20	.	.	.
cord-264050-6zpw6itb	83	1	The	the	DT
cord-264050-6zpw6itb	83	2	aforementioned	aforementioned	JJ
cord-264050-6zpw6itb	83	3	experimental	experimental	JJ
cord-264050-6zpw6itb	83	4	models	model	NNS
cord-264050-6zpw6itb	83	5	provide	provide	VBP
cord-264050-6zpw6itb	83	6	possible	possible	JJ
cord-264050-6zpw6itb	83	7	mechanistic	mechanistic	JJ
cord-264050-6zpw6itb	83	8	explanations	explanation	NNS
cord-264050-6zpw6itb	83	9	for	for	IN
cord-264050-6zpw6itb	83	10	the	the	DT
cord-264050-6zpw6itb	83	11	dichotomous	dichotomous	JJ
cord-264050-6zpw6itb	83	12	role	role	NN
cord-264050-6zpw6itb	83	13	that	that	IN
cord-264050-6zpw6itb	83	14	the	the	DT
cord-264050-6zpw6itb	83	15	immune	immune	JJ
cord-264050-6zpw6itb	83	16	response	response	NN
cord-264050-6zpw6itb	83	17	may	may	MD
cord-264050-6zpw6itb	83	18	play	play	VB
cord-264050-6zpw6itb	83	19	in	in	IN
cord-264050-6zpw6itb	83	20	the	the	DT
cord-264050-6zpw6itb	83	21	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	83	22	of	of	IN
cord-264050-6zpw6itb	83	23	IRIS	IRIS	NNP
cord-264050-6zpw6itb	83	24	-	-	HYPH
cord-264050-6zpw6itb	83	25	and	and	CC
cord-264050-6zpw6itb	83	26	PIIRS	PIIRS	NNP
cord-264050-6zpw6itb	83	27	-	-	HYPH
cord-264050-6zpw6itb	83	28	associated	associate	VBN
cord-264050-6zpw6itb	83	29	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	83	30	while	while	IN
cord-264050-6zpw6itb	83	31	contributing	contribute	VBG
cord-264050-6zpw6itb	83	32	to	to	IN
cord-264050-6zpw6itb	83	33	fungal	fungal	JJ
cord-264050-6zpw6itb	83	34	clearance	clearance	NN
cord-264050-6zpw6itb	83	35	.	.	.
cord-264050-6zpw6itb	84	1	Thus	thus	RB
cord-264050-6zpw6itb	84	2	,	,	,
cord-264050-6zpw6itb	84	3	microbe	microbe	NN
cord-264050-6zpw6itb	84	4	and	and	CC
cord-264050-6zpw6itb	84	5	host	host	NN
cord-264050-6zpw6itb	84	6	both	both	DT
cord-264050-6zpw6itb	84	7	contribute	contribute	VBP
cord-264050-6zpw6itb	84	8	to	to	TO
cord-264050-6zpw6itb	84	9	host	host	NN
cord-264050-6zpw6itb	84	10	damage	damage	NN
cord-264050-6zpw6itb	84	11	and	and	CC
cord-264050-6zpw6itb	85	1	where	where	WRB
cord-264050-6zpw6itb	85	2	an	an	DT
cord-264050-6zpw6itb	85	3	individual	individual	JJ
cord-264050-6zpw6itb	85	4	patient	patient	NN
cord-264050-6zpw6itb	85	5	's	's	POS
cord-264050-6zpw6itb	85	6	immune	immune	JJ
cord-264050-6zpw6itb	85	7	response	response	NN
cord-264050-6zpw6itb	85	8	lies	lie	VBZ
cord-264050-6zpw6itb	85	9	on	on	IN
cord-264050-6zpw6itb	85	10	the	the	DT
cord-264050-6zpw6itb	85	11	continuum	continuum	NN
cord-264050-6zpw6itb	85	12	of	of	IN
cord-264050-6zpw6itb	85	13	the	the	DT
cord-264050-6zpw6itb	85	14	DRF	DRF	NNP
cord-264050-6zpw6itb	85	15	parabola	parabola	NN
cord-264050-6zpw6itb	85	16	determines	determine	VBZ
cord-264050-6zpw6itb	85	17	the	the	DT
cord-264050-6zpw6itb	85	18	nature	nature	NN
cord-264050-6zpw6itb	85	19	of	of	IN
cord-264050-6zpw6itb	85	20	the	the	DT
cord-264050-6zpw6itb	85	21	disease	disease	NN
cord-264050-6zpw6itb	85	22	process	process	NN
cord-264050-6zpw6itb	85	23	.	.	.
cord-264050-6zpw6itb	86	1	At	at	IN
cord-264050-6zpw6itb	86	2	one	one	CD
cord-264050-6zpw6itb	86	3	end	end	NN
cord-264050-6zpw6itb	86	4	,	,	,
cord-264050-6zpw6itb	86	5	on	on	IN
cord-264050-6zpw6itb	86	6	the	the	DT
cord-264050-6zpw6itb	86	7	left	left	NN
cord-264050-6zpw6itb	86	8	,	,	,
cord-264050-6zpw6itb	86	9	a	a	DT
cord-264050-6zpw6itb	86	10	weak	weak	JJ
cord-264050-6zpw6itb	86	11	immune	immune	JJ
cord-264050-6zpw6itb	86	12	response	response	NN
cord-264050-6zpw6itb	86	13	can	can	MD
cord-264050-6zpw6itb	86	14	result	result	VB
cord-264050-6zpw6itb	86	15	in	in	IN
cord-264050-6zpw6itb	86	16	tissue	tissue	NN
cord-264050-6zpw6itb	86	17	damage	damage	NN
cord-264050-6zpw6itb	86	18	due	due	JJ
cord-264050-6zpw6itb	86	19	to	to	IN
cord-264050-6zpw6itb	86	20	fungal	fungal	JJ
cord-264050-6zpw6itb	86	21	proliferation	proliferation	NN
cord-264050-6zpw6itb	86	22	that	that	IN
cord-264050-6zpw6itb	86	23	results	result	NNS
cord-264050-6zpw6itb	86	24	in	in	IN
cord-264050-6zpw6itb	86	25	compression	compression	NN
cord-264050-6zpw6itb	86	26	of	of	IN
cord-264050-6zpw6itb	86	27	brain	brain	NN
cord-264050-6zpw6itb	86	28	tissue	tissue	NN
cord-264050-6zpw6itb	86	29	with	with	IN
cord-264050-6zpw6itb	86	30	little	little	JJ
cord-264050-6zpw6itb	86	31	or	or	CC
cord-264050-6zpw6itb	86	32	no	no	DT
cord-264050-6zpw6itb	86	33	inflammation	inflammation	NN
cord-264050-6zpw6itb	86	34	in	in	IN
cord-264050-6zpw6itb	86	35	what	what	WP
cord-264050-6zpw6itb	86	36	is	be	VBZ
cord-264050-6zpw6itb	86	37	primarily	primarily	RB
cord-264050-6zpw6itb	86	38	microbe	microbe	NN
cord-264050-6zpw6itb	86	39	-	-	HYPH
cord-264050-6zpw6itb	86	40	mediated	mediate	VBN
cord-264050-6zpw6itb	86	41	damage	damage	NN
cord-264050-6zpw6itb	86	42	.	.	.
cord-264050-6zpw6itb	87	1	At	at	IN
cord-264050-6zpw6itb	87	2	the	the	DT
cord-264050-6zpw6itb	87	3	other	other	JJ
cord-264050-6zpw6itb	87	4	end	end	NN
cord-264050-6zpw6itb	87	5	,	,	,
cord-264050-6zpw6itb	87	6	on	on	IN
cord-264050-6zpw6itb	87	7	the	the	DT
cord-264050-6zpw6itb	87	8	right	right	NN
cord-264050-6zpw6itb	87	9	,	,	,
cord-264050-6zpw6itb	87	10	a	a	DT
cord-264050-6zpw6itb	87	11	strong	strong	JJ
cord-264050-6zpw6itb	87	12	cellular	cellular	JJ
cord-264050-6zpw6itb	87	13	immune	immune	JJ
cord-264050-6zpw6itb	87	14	response	response	NN
cord-264050-6zpw6itb	87	15	can	can	MD
cord-264050-6zpw6itb	87	16	also	also	RB
cord-264050-6zpw6itb	87	17	damage	damage	VB
cord-264050-6zpw6itb	87	18	brain	brain	NN
cord-264050-6zpw6itb	87	19	tissue	tissue	NN
cord-264050-6zpw6itb	87	20	due	due	IN
cord-264050-6zpw6itb	87	21	to	to	IN
cord-264050-6zpw6itb	87	22	excessive	excessive	JJ
cord-264050-6zpw6itb	87	23	inflammation	inflammation	NN
cord-264050-6zpw6itb	87	24	in	in	IN
cord-264050-6zpw6itb	87	25	what	what	WP
cord-264050-6zpw6itb	87	26	is	be	VBZ
cord-264050-6zpw6itb	87	27	primarily	primarily	RB
cord-264050-6zpw6itb	87	28	host	host	NN
cord-264050-6zpw6itb	87	29	-	-	HYPH
cord-264050-6zpw6itb	87	30	mediated	mediate	VBN
cord-264050-6zpw6itb	87	31	damage	damage	NN
cord-264050-6zpw6itb	87	32	.	.	.
cord-264050-6zpw6itb	88	1	The	the	DT
cord-264050-6zpw6itb	88	2	occurrence	occurrence	NN
cord-264050-6zpw6itb	88	3	of	of	IN
cord-264050-6zpw6itb	88	4	host	host	NN
cord-264050-6zpw6itb	88	5	damage	damage	NN
cord-264050-6zpw6itb	88	6	in	in	IN
cord-264050-6zpw6itb	88	7	the	the	DT
cord-264050-6zpw6itb	88	8	setting	setting	NN
cord-264050-6zpw6itb	88	9	of	of	IN
cord-264050-6zpw6itb	88	10	weak	weak	JJ
cord-264050-6zpw6itb	88	11	and	and	CC
cord-264050-6zpw6itb	88	12	strong	strong	JJ
cord-264050-6zpw6itb	88	13	immune	immune	JJ
cord-264050-6zpw6itb	88	14	responses	response	NNS
cord-264050-6zpw6itb	88	15	provides	provide	VBZ
cord-264050-6zpw6itb	88	16	important	important	JJ
cord-264050-6zpw6itb	88	17	clues	clue	NNS
cord-264050-6zpw6itb	88	18	as	as	IN
cord-264050-6zpw6itb	88	19	to	to	IN
cord-264050-6zpw6itb	88	20	why	why	WRB
cord-264050-6zpw6itb	88	21	it	-PRON-	PRP
cord-264050-6zpw6itb	88	22	has	have	VBZ
cord-264050-6zpw6itb	88	23	been	be	VBN
cord-264050-6zpw6itb	88	24	so	so	RB
cord-264050-6zpw6itb	88	25	difficult	difficult	JJ
cord-264050-6zpw6itb	88	26	to	to	TO
cord-264050-6zpw6itb	88	27	consistently	consistently	RB
cord-264050-6zpw6itb	88	28	use	use	VB
cord-264050-6zpw6itb	88	29	agents	agent	NNS
cord-264050-6zpw6itb	88	30	that	that	WDT
cord-264050-6zpw6itb	88	31	modulate	modulate	VBP
cord-264050-6zpw6itb	88	32	inflammation	inflammation	NN
cord-264050-6zpw6itb	88	33	,	,	,
cord-264050-6zpw6itb	88	34	such	such	JJ
cord-264050-6zpw6itb	88	35	as	as	IN
cord-264050-6zpw6itb	88	36	corticosteroids	corticosteroid	NNS
cord-264050-6zpw6itb	88	37	and	and	CC
cord-264050-6zpw6itb	88	38	interferon	interferon	NN
cord-264050-6zpw6itb	88	39	,	,	,
cord-264050-6zpw6itb	88	40	to	to	TO
cord-264050-6zpw6itb	88	41	improve	improve	VB
cord-264050-6zpw6itb	88	42	the	the	DT
cord-264050-6zpw6itb	88	43	outcome	outcome	NN
cord-264050-6zpw6itb	88	44	of	of	IN
cord-264050-6zpw6itb	88	45	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	88	46	.	.	.
cord-264050-6zpw6itb	89	1	Although	although	IN
cord-264050-6zpw6itb	89	2	adjunctive	adjunctive	JJ
cord-264050-6zpw6itb	89	3	IFN-	IFN-	NNP
cord-264050-6zpw6itb	89	4	␥	␥	CD
cord-264050-6zpw6itb	89	5	therapy	therapy	NN
cord-264050-6zpw6itb	89	6	in	in	IN
cord-264050-6zpw6itb	89	7	HIV	HIV	NNP
cord-264050-6zpw6itb	89	8	-	-	HYPH
cord-264050-6zpw6itb	89	9	associated	associate	VBN
cord-264050-6zpw6itb	89	10	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	89	11	(	(	-LRB-
cord-264050-6zpw6itb	89	12	27	27	CD
cord-264050-6zpw6itb	89	13	)	)	-RRB-
cord-264050-6zpw6itb	89	14	and	and	CC
cord-264050-6zpw6itb	89	15	corticosteroids	corticosteroid	NNS
cord-264050-6zpw6itb	89	16	can	can	MD
cord-264050-6zpw6itb	89	17	ameliorate	ameliorate	VB
cord-264050-6zpw6itb	89	18	IRIS	IRIS	NNP
cord-264050-6zpw6itb	89	19	(	(	-LRB-
cord-264050-6zpw6itb	89	20	28	28	CD
cord-264050-6zpw6itb	89	21	)	)	-RRB-
cord-264050-6zpw6itb	89	22	in	in	IN
cord-264050-6zpw6itb	89	23	some	some	DT
cord-264050-6zpw6itb	89	24	patients	patient	NNS
cord-264050-6zpw6itb	89	25	,	,	,
cord-264050-6zpw6itb	89	26	such	such	JJ
cord-264050-6zpw6itb	89	27	immune	immune	NN
cord-264050-6zpw6itb	89	28	-	-	HYPH
cord-264050-6zpw6itb	89	29	modulating	modulate	VBG
cord-264050-6zpw6itb	89	30	agents	agent	NNS
cord-264050-6zpw6itb	89	31	may	may	MD
cord-264050-6zpw6itb	89	32	not	not	RB
cord-264050-6zpw6itb	89	33	be	be	VB
cord-264050-6zpw6itb	89	34	effective	effective	JJ
cord-264050-6zpw6itb	89	35	in	in	IN
cord-264050-6zpw6itb	89	36	other	other	JJ
cord-264050-6zpw6itb	89	37	patients	patient	NNS
cord-264050-6zpw6itb	89	38	,	,	,
cord-264050-6zpw6itb	89	39	because	because	IN
cord-264050-6zpw6itb	89	40	physicians	physician	NNS
cord-264050-6zpw6itb	89	41	do	do	VBP
cord-264050-6zpw6itb	89	42	not	not	RB
cord-264050-6zpw6itb	89	43	usually	usually	RB
cord-264050-6zpw6itb	89	44	know	know	VB
cord-264050-6zpw6itb	89	45	whether	whether	IN
cord-264050-6zpw6itb	89	46	the	the	DT
cord-264050-6zpw6itb	89	47	preponderance	preponderance	NN
cord-264050-6zpw6itb	89	48	of	of	IN
cord-264050-6zpw6itb	89	49	damage	damage	NN
cord-264050-6zpw6itb	89	50	is	be	VBZ
cord-264050-6zpw6itb	89	51	due	due	JJ
cord-264050-6zpw6itb	89	52	to	to	IN
cord-264050-6zpw6itb	89	53	host	host	NN
cord-264050-6zpw6itb	89	54	factors	factor	NNS
cord-264050-6zpw6itb	89	55	,	,	,
cord-264050-6zpw6itb	89	56	microbial	microbial	JJ
cord-264050-6zpw6itb	89	57	factors	factor	NNS
cord-264050-6zpw6itb	89	58	,	,	,
cord-264050-6zpw6itb	89	59	or	or	CC
cord-264050-6zpw6itb	89	60	both	both	DT
cord-264050-6zpw6itb	89	61	.	.	.
cord-264050-6zpw6itb	90	1	In	in	IN
cord-264050-6zpw6itb	90	2	this	this	DT
cord-264050-6zpw6itb	90	3	regard	regard	NN
cord-264050-6zpw6itb	90	4	,	,	,
cord-264050-6zpw6itb	90	5	the	the	DT
cord-264050-6zpw6itb	90	6	failure	failure	NN
cord-264050-6zpw6itb	90	7	and	and	CC
cord-264050-6zpw6itb	90	8	detrimental	detrimental	JJ
cord-264050-6zpw6itb	90	9	effects	effect	NNS
cord-264050-6zpw6itb	90	10	of	of	IN
cord-264050-6zpw6itb	90	11	steroid	steroid	NN
cord-264050-6zpw6itb	90	12	therapy	therapy	NN
cord-264050-6zpw6itb	90	13	in	in	IN
cord-264050-6zpw6itb	90	14	patients	patient	NNS
cord-264050-6zpw6itb	90	15	with	with	IN
cord-264050-6zpw6itb	90	16	HIV	HIV	NNP
cord-264050-6zpw6itb	90	17	-	-	HYPH
cord-264050-6zpw6itb	90	18	associated	associate	VBN
cord-264050-6zpw6itb	90	19	cryptococcosis	cryptococcosis	NNP
cord-264050-6zpw6itb	90	20	(	(	-LRB-
cord-264050-6zpw6itb	90	21	19	19	CD
cord-264050-6zpw6itb	90	22	)	)	-RRB-
cord-264050-6zpw6itb	90	23	probably	probably	RB
cord-264050-6zpw6itb	90	24	represent	represent	VBP
cord-264050-6zpw6itb	90	25	additional	additional	JJ
cord-264050-6zpw6itb	90	26	suppression	suppression	NN
cord-264050-6zpw6itb	90	27	of	of	IN
cord-264050-6zpw6itb	90	28	weak	weak	JJ
cord-264050-6zpw6itb	90	29	immunity	immunity	NN
cord-264050-6zpw6itb	90	30	resulting	result	VBG
cord-264050-6zpw6itb	90	31	in	in	IN
cord-264050-6zpw6itb	90	32	enhancement	enhancement	NN
cord-264050-6zpw6itb	90	33	of	of	IN
cord-264050-6zpw6itb	90	34	fungus	fungus	NN
cord-264050-6zpw6itb	90	35	-	-	HYPH
cord-264050-6zpw6itb	90	36	mediated	mediate	VBN
cord-264050-6zpw6itb	90	37	damage	damage	NN
cord-264050-6zpw6itb	90	38	.	.	.
cord-264050-6zpw6itb	91	1	Hence	hence	RB
cord-264050-6zpw6itb	91	2	,	,	,
cord-264050-6zpw6itb	91	3	the	the	DT
cord-264050-6zpw6itb	91	4	effective	effective	JJ
cord-264050-6zpw6itb	91	5	use	use	NN
cord-264050-6zpw6itb	91	6	of	of	IN
cord-264050-6zpw6itb	91	7	immunotherapy	immunotherapy	NN
cord-264050-6zpw6itb	91	8	is	be	VBZ
cord-264050-6zpw6itb	91	9	likely	likely	JJ
cord-264050-6zpw6itb	91	10	to	to	TO
cord-264050-6zpw6itb	91	11	require	require	VB
cord-264050-6zpw6itb	91	12	a	a	DT
cord-264050-6zpw6itb	91	13	rational	rational	JJ
cord-264050-6zpw6itb	91	14	approach	approach	NN
cord-264050-6zpw6itb	91	15	that	that	WDT
cord-264050-6zpw6itb	91	16	incorporates	incorporate	VBZ
cord-264050-6zpw6itb	91	17	knowledge	knowledge	NN
cord-264050-6zpw6itb	91	18	of	of	IN
cord-264050-6zpw6itb	91	19	where	where	WRB
cord-264050-6zpw6itb	91	20	the	the	DT
cord-264050-6zpw6itb	91	21	immune	immune	JJ
cord-264050-6zpw6itb	91	22	response	response	NN
cord-264050-6zpw6itb	91	23	of	of	IN
cord-264050-6zpw6itb	91	24	an	an	DT
cord-264050-6zpw6itb	91	25	individual	individual	JJ
cord-264050-6zpw6itb	91	26	lies	lie	VBZ
cord-264050-6zpw6itb	91	27	along	along	IN
cord-264050-6zpw6itb	91	28	the	the	DT
cord-264050-6zpw6itb	91	29	immune	immune	JJ
cord-264050-6zpw6itb	91	30	response	response	NN
cord-264050-6zpw6itb	91	31	co	co	NNP
cord-264050-6zpw6itb	91	32	ntinuum	ntinuum	NN
cord-264050-6zpw6itb	91	33	depicted	depict	VBN
cord-264050-6zpw6itb	91	34	by	by	IN
cord-264050-6zpw6itb	91	35	the	the	DT
cord-264050-6zpw6itb	91	36	DRF	DRF	NNP
cord-264050-6zpw6itb	91	37	parabola	parabola	NN
cord-264050-6zpw6itb	91	38	.	.	.
cord-264050-6zpw6itb	92	1	Host	host	NN
cord-264050-6zpw6itb	92	2	-	-	HYPH
cord-264050-6zpw6itb	92	3	pathogen	pathogen	NN
cord-264050-6zpw6itb	92	4	interactions	interaction	NNS
cord-264050-6zpw6itb	92	5	:	:	:
cord-264050-6zpw6itb	93	1	the	the	DT
cord-264050-6zpw6itb	93	2	attributes	attribute	NNS
cord-264050-6zpw6itb	93	3	of	of	IN
cord-264050-6zpw6itb	93	4	virulence	virulence	NN
cord-264050-6zpw6itb	93	5	CD4	CD4	NNP
cord-264050-6zpw6itb	93	6	ϩ	ϩ	NNP
cord-264050-6zpw6itb	93	7	T	t	NN
cord-264050-6zpw6itb	93	8	cells	cell	NNS
cord-264050-6zpw6itb	93	9	orchestrate	orchestrate	VBP
cord-264050-6zpw6itb	93	10	lethal	lethal	JJ
cord-264050-6zpw6itb	93	11	immune	immune	JJ
cord-264050-6zpw6itb	93	12	pathology	pathology	NN
cord-264050-6zpw6itb	93	13	despite	despite	IN
cord-264050-6zpw6itb	93	14	fungal	fungal	JJ
cord-264050-6zpw6itb	93	15	clearance	clearance	NN
cord-264050-6zpw6itb	93	16	during	during	IN
cord-264050-6zpw6itb	93	17	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	93	18	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	93	19	meningoencephalitis	meningoencephalitis	IN
cord-264050-6zpw6itb	93	20	Host	host	NN
cord-264050-6zpw6itb	93	21	-	-	HYPH
cord-264050-6zpw6itb	93	22	pathogen	pathogen	NN
cord-264050-6zpw6itb	93	23	interactions	interaction	NNS
cord-264050-6zpw6itb	93	24	:	:	:
cord-264050-6zpw6itb	93	25	redefining	redefine	VBG
cord-264050-6zpw6itb	93	26	the	the	DT
cord-264050-6zpw6itb	93	27	basic	basic	JJ
cord-264050-6zpw6itb	93	28	concepts	concept	NNS
cord-264050-6zpw6itb	93	29	of	of	IN
cord-264050-6zpw6itb	93	30	virulence	virulence	NN
cord-264050-6zpw6itb	93	31	and	and	CC
cord-264050-6zpw6itb	93	32	pathogenicity	pathogenicity	NN
cord-264050-6zpw6itb	94	1	What	what	WP
cord-264050-6zpw6itb	94	2	is	be	VBZ
cord-264050-6zpw6itb	94	3	a	a	DT
cord-264050-6zpw6itb	94	4	host	host	NN
cord-264050-6zpw6itb	94	5	?	?	.
cord-264050-6zpw6itb	95	1	Incorporating	incorporate	VBG
cord-264050-6zpw6itb	95	2	the	the	DT
cord-264050-6zpw6itb	95	3	microbiota	microbiota	NN
cord-264050-6zpw6itb	95	4	into	into	IN
cord-264050-6zpw6itb	95	5	the	the	DT
cord-264050-6zpw6itb	95	6	damage	damage	NN
cord-264050-6zpw6itb	95	7	-	-	HYPH
cord-264050-6zpw6itb	95	8	response	response	NN
cord-264050-6zpw6itb	95	9	framework	framework	NN
cord-264050-6zpw6itb	95	10	A	a	DT
cord-264050-6zpw6itb	95	11	clinicopathological	clinicopathological	JJ
cord-264050-6zpw6itb	95	12	study	study	NN
cord-264050-6zpw6itb	95	13	of	of	IN
cord-264050-6zpw6itb	95	14	three	three	CD
cord-264050-6zpw6itb	95	15	cases	case	NNS
cord-264050-6zpw6itb	95	16	of	of	IN
cord-264050-6zpw6itb	95	17	severe	severe	JJ
cord-264050-6zpw6itb	95	18	acute	acute	JJ
cord-264050-6zpw6itb	95	19	respiratory	respiratory	JJ
cord-264050-6zpw6itb	95	20	syndrome	syndrome	NN
cord-264050-6zpw6itb	95	21	(	(	-LRB-
cord-264050-6zpw6itb	95	22	SARS	SARS	NNP
cord-264050-6zpw6itb	95	23	)	)	-RRB-
cord-264050-6zpw6itb	96	1	The	the	DT
cord-264050-6zpw6itb	96	2	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	96	3	of	of	IN
cord-264050-6zpw6itb	96	4	influenza	influenza	NN
cord-264050-6zpw6itb	96	5	virus	virus	NN
cord-264050-6zpw6itb	96	6	infections	infection	NNS
cord-264050-6zpw6itb	96	7	:	:	:
cord-264050-6zpw6itb	96	8	the	the	DT
cord-264050-6zpw6itb	96	9	contributions	contribution	NNS
cord-264050-6zpw6itb	96	10	of	of	IN
cord-264050-6zpw6itb	96	11	virus	virus	NN
cord-264050-6zpw6itb	96	12	and	and	CC
cord-264050-6zpw6itb	96	13	host	host	NN
cord-264050-6zpw6itb	96	14	factors	factor	NNS
cord-264050-6zpw6itb	96	15	Spread	Spread	VBN
cord-264050-6zpw6itb	96	16	of	of	IN
cord-264050-6zpw6itb	96	17	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	96	18	gattii	gattii	NN
cord-264050-6zpw6itb	96	19	into	into	IN
cord-264050-6zpw6itb	96	20	Pacific	Pacific	NNP
cord-264050-6zpw6itb	96	21	Northwest	Northwest	NNP
cord-264050-6zpw6itb	96	22	region	region	NN
cord-264050-6zpw6itb	96	23	of	of	IN
cord-264050-6zpw6itb	96	24	the	the	DT
cord-264050-6zpw6itb	96	25	United	United	NNP
cord-264050-6zpw6itb	96	26	States	States	NNP
cord-264050-6zpw6itb	96	27	Paucity	Paucity	NNP
cord-264050-6zpw6itb	96	28	of	of	IN
cord-264050-6zpw6itb	96	29	initial	initial	JJ
cord-264050-6zpw6itb	96	30	cerebrospinal	cerebrospinal	JJ
cord-264050-6zpw6itb	96	31	fluid	fluid	JJ
cord-264050-6zpw6itb	96	32	inflammation	inflammation	NN
cord-264050-6zpw6itb	96	33	in	in	IN
cord-264050-6zpw6itb	96	34	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	96	35	meningitis	meningitis	NN
cord-264050-6zpw6itb	96	36	is	be	VBZ
cord-264050-6zpw6itb	96	37	associated	associate	VBN
cord-264050-6zpw6itb	96	38	with	with	IN
cord-264050-6zpw6itb	96	39	subsequent	subsequent	JJ
cord-264050-6zpw6itb	96	40	immune	immune	JJ
cord-264050-6zpw6itb	96	41	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	96	42	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	96	43	syndrome	syndrome	NN
cord-264050-6zpw6itb	96	44	International	International	NNP
cord-264050-6zpw6itb	96	45	Network	Network	NNP
cord-264050-6zpw6itb	96	46	for	for	IN
cord-264050-6zpw6itb	96	47	the	the	DT
cord-264050-6zpw6itb	96	48	Study	Study	NNP
cord-264050-6zpw6itb	96	49	of	of	IN
cord-264050-6zpw6itb	96	50	HIV	HIV	NNP
cord-264050-6zpw6itb	96	51	-	-	HYPH
cord-264050-6zpw6itb	96	52	associated	associate	VBN
cord-264050-6zpw6itb	96	53	IRIS	IRIS	NNP
cord-264050-6zpw6itb	96	54	(	(	-LRB-
cord-264050-6zpw6itb	96	55	INSHI	INSHI	NNP
cord-264050-6zpw6itb	96	56	)	)	-RRB-
cord-264050-6zpw6itb	96	57	.	.	.
cord-264050-6zpw6itb	97	1	2010	2010	CD
cord-264050-6zpw6itb	97	2	.	.	.
cord-264050-6zpw6itb	98	1	Cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	98	2	immune	immune	JJ
cord-264050-6zpw6itb	98	3	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	98	4	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	98	5	syndrome	syndrome	NN
cord-264050-6zpw6itb	98	6	in	in	IN
cord-264050-6zpw6itb	98	7	HIV-1-infected	hiv-1-infecte	VBN
cord-264050-6zpw6itb	98	8	individuals	individual	NNS
cord-264050-6zpw6itb	98	9	:	:	:
cord-264050-6zpw6itb	98	10	proposed	propose	VBN
cord-264050-6zpw6itb	98	11	clinical	clinical	JJ
cord-264050-6zpw6itb	98	12	case	case	NN
cord-264050-6zpw6itb	98	13	definitions	definition	NNS
cord-264050-6zpw6itb	99	1	The	the	DT
cord-264050-6zpw6itb	99	2	expanding	expand	VBG
cord-264050-6zpw6itb	99	3	role	role	NN
cord-264050-6zpw6itb	99	4	of	of	IN
cord-264050-6zpw6itb	99	5	co	co	JJ
cord-264050-6zpw6itb	99	6	-	-	JJ
cord-264050-6zpw6itb	99	7	trimoxazole	trimoxazole	NN
cord-264050-6zpw6itb	99	8	in	in	IN
cord-264050-6zpw6itb	99	9	developing	develop	VBG
cord-264050-6zpw6itb	99	10	countries	country	NNS
cord-264050-6zpw6itb	99	11	Anti	anti	JJ
cord-264050-6zpw6itb	99	12	-	-	JJ
cord-264050-6zpw6itb	99	13	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	99	14	treatment	treatment	NN
cord-264050-6zpw6itb	99	15	of	of	IN
cord-264050-6zpw6itb	99	16	acute	acute	JJ
cord-264050-6zpw6itb	99	17	and	and	CC
cord-264050-6zpw6itb	99	18	chronic	chronic	JJ
cord-264050-6zpw6itb	99	19	pneumonia	pneumonia	NN
cord-264050-6zpw6itb	99	20	Immune	immune	NN
cord-264050-6zpw6itb	99	21	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	99	22	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	99	23	syndrome	syndrome	NN
cord-264050-6zpw6itb	99	24	in	in	IN
cord-264050-6zpw6itb	99	25	HIV	HIV	NNP
cord-264050-6zpw6itb	99	26	-	-	HYPH
cord-264050-6zpw6itb	99	27	associated	associate	VBN
cord-264050-6zpw6itb	99	28	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	99	29	meningitis	meningitis	NN
cord-264050-6zpw6itb	99	30	:	:	:
cord-264050-6zpw6itb	99	31	a	a	DT
cord-264050-6zpw6itb	99	32	prospective	prospective	JJ
cord-264050-6zpw6itb	99	33	study	study	NN
cord-264050-6zpw6itb	99	34	Chemokine	chemokine	JJ
cord-264050-6zpw6itb	99	35	levels	level	NNS
cord-264050-6zpw6itb	99	36	and	and	CC
cord-264050-6zpw6itb	99	37	chemokine	chemokine	NN
cord-264050-6zpw6itb	99	38	receptor	receptor	NN
cord-264050-6zpw6itb	99	39	expression	expression	NN
cord-264050-6zpw6itb	99	40	in	in	IN
cord-264050-6zpw6itb	99	41	the	the	DT
cord-264050-6zpw6itb	99	42	blood	blood	NN
cord-264050-6zpw6itb	99	43	and	and	CC
cord-264050-6zpw6itb	99	44	the	the	DT
cord-264050-6zpw6itb	99	45	cerebrospinal	cerebrospinal	JJ
cord-264050-6zpw6itb	99	46	fluid	fluid	NN
cord-264050-6zpw6itb	99	47	of	of	IN
cord-264050-6zpw6itb	99	48	HIV	HIV	NNP
cord-264050-6zpw6itb	99	49	-	-	HYPH
cord-264050-6zpw6itb	99	50	infected	infect	VBN
cord-264050-6zpw6itb	99	51	patients	patient	NNS
cord-264050-6zpw6itb	99	52	with	with	IN
cord-264050-6zpw6itb	99	53	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	99	54	meningitis	meningitis	NN
cord-264050-6zpw6itb	99	55	and	and	CC
cord-264050-6zpw6itb	99	56	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	99	57	-	-	HYPH
cord-264050-6zpw6itb	99	58	associated	associate	VBN
cord-264050-6zpw6itb	99	59	immune	immune	JJ
cord-264050-6zpw6itb	99	60	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	99	61	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	99	62	syndrome	syndrome	NN
cord-264050-6zpw6itb	99	63	Cellular	cellular	JJ
cord-264050-6zpw6itb	99	64	immune	immune	JJ
cord-264050-6zpw6itb	99	65	activation	activation	NN
cord-264050-6zpw6itb	99	66	in	in	IN
cord-264050-6zpw6itb	99	67	cerebrospinal	cerebrospinal	JJ
cord-264050-6zpw6itb	99	68	fluid	fluid	NN
cord-264050-6zpw6itb	99	69	from	from	IN
cord-264050-6zpw6itb	99	70	Ugandans	Ugandans	NNPS
cord-264050-6zpw6itb	99	71	with	with	IN
cord-264050-6zpw6itb	99	72	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	99	73	meningitis	meningitis	NN
cord-264050-6zpw6itb	99	74	and	and	CC
cord-264050-6zpw6itb	99	75	immune	immune	JJ
cord-264050-6zpw6itb	99	76	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	99	77	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	99	78	syndrome	syndrome	NN
cord-264050-6zpw6itb	100	1	The	the	DT
cord-264050-6zpw6itb	100	2	immunopathogenesis	immunopathogenesis	NN
cord-264050-6zpw6itb	100	3	of	of	IN
cord-264050-6zpw6itb	100	4	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	100	5	immune	immune	JJ
cord-264050-6zpw6itb	100	6	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	100	7	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	100	8	syndrome	syndrome	NN
cord-264050-6zpw6itb	100	9	:	:	:
cord-264050-6zpw6itb	100	10	understanding	understand	VBG
cord-264050-6zpw6itb	100	11	a	a	DT
cord-264050-6zpw6itb	100	12	conundrum	conundrum	NN
cord-264050-6zpw6itb	100	13	Paradoxical	paradoxical	JJ
cord-264050-6zpw6itb	100	14	immune	immune	JJ
cord-264050-6zpw6itb	100	15	responses	response	NNS
cord-264050-6zpw6itb	100	16	in	in	IN
cord-264050-6zpw6itb	100	17	non	non	JJ
cord-264050-6zpw6itb	100	18	-	-	JJ
cord-264050-6zpw6itb	100	19	HIV	hiv	JJ
cord-264050-6zpw6itb	100	20	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	100	21	meningitis	meningitis	NN
cord-264050-6zpw6itb	100	22	Fighting	fight	VBG
cord-264050-6zpw6itb	100	23	the	the	DT
cord-264050-6zpw6itb	100	24	monster	monster	NN
cord-264050-6zpw6itb	100	25	:	:	:
cord-264050-6zpw6itb	100	26	applying	apply	VBG
cord-264050-6zpw6itb	100	27	the	the	DT
cord-264050-6zpw6itb	100	28	host	host	NN
cord-264050-6zpw6itb	100	29	damage	damage	NN
cord-264050-6zpw6itb	100	30	framework	framework	NN
cord-264050-6zpw6itb	100	31	to	to	IN
cord-264050-6zpw6itb	100	32	human	human	JJ
cord-264050-6zpw6itb	100	33	central	central	JJ
cord-264050-6zpw6itb	100	34	nervous	nervous	JJ
cord-264050-6zpw6itb	100	35	system	system	NN
cord-264050-6zpw6itb	100	36	infections	infection	NNS
cord-264050-6zpw6itb	100	37	A	a	DT
cord-264050-6zpw6itb	100	38	novel	novel	JJ
cord-264050-6zpw6itb	100	39	experimental	experimental	JJ
cord-264050-6zpw6itb	100	40	model	model	NN
cord-264050-6zpw6itb	100	41	of	of	IN
cord-264050-6zpw6itb	100	42	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	100	43	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	100	44	-	-	HYPH
cord-264050-6zpw6itb	100	45	related	relate	VBN
cord-264050-6zpw6itb	100	46	immune	immune	JJ
cord-264050-6zpw6itb	100	47	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	100	48	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	100	49	syndrome	syndrome	NN
cord-264050-6zpw6itb	100	50	(	(	-LRB-
cord-264050-6zpw6itb	100	51	IRIS	IRIS	NNP
cord-264050-6zpw6itb	100	52	)	)	-RRB-
cord-264050-6zpw6itb	100	53	provides	provide	VBZ
cord-264050-6zpw6itb	100	54	insights	insight	NNS
cord-264050-6zpw6itb	100	55	into	into	IN
cord-264050-6zpw6itb	100	56	pathogenesis	pathogenesis	NN
cord-264050-6zpw6itb	100	57	Adjunctive	Adjunctive	NNP
cord-264050-6zpw6itb	100	58	dexamethasone	dexamethasone	NN
cord-264050-6zpw6itb	100	59	in	in	IN
cord-264050-6zpw6itb	100	60	HIV	HIV	NNP
cord-264050-6zpw6itb	100	61	-	-	HYPH
cord-264050-6zpw6itb	100	62	associated	associate	VBN
cord-264050-6zpw6itb	100	63	cryptococcal	cryptococcal	NN
cord-264050-6zpw6itb	100	64	meningitis	meningitis	NN
cord-264050-6zpw6itb	100	65	Predictors	Predictors	NNP
cord-264050-6zpw6itb	100	66	of	of	IN
cord-264050-6zpw6itb	100	67	mortality	mortality	NN
cord-264050-6zpw6itb	100	68	and	and	CC
cord-264050-6zpw6itb	100	69	differences	difference	NNS
cord-264050-6zpw6itb	100	70	in	in	IN
cord-264050-6zpw6itb	100	71	clinical	clinical	JJ
cord-264050-6zpw6itb	100	72	features	feature	NNS
cord-264050-6zpw6itb	100	73	among	among	IN
cord-264050-6zpw6itb	100	74	patients	patient	NNS
cord-264050-6zpw6itb	100	75	with	with	IN
cord-264050-6zpw6itb	100	76	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	100	77	according	accord	VBG
cord-264050-6zpw6itb	100	78	to	to	IN
cord-264050-6zpw6itb	100	79	immune	immune	JJ
cord-264050-6zpw6itb	100	80	status	status	NN
cord-264050-6zpw6itb	101	1	Different	different	JJ
cord-264050-6zpw6itb	101	2	presentations	presentation	NNS
cord-264050-6zpw6itb	101	3	and	and	CC
cord-264050-6zpw6itb	101	4	outcomes	outcome	NNS
cord-264050-6zpw6itb	101	5	between	between	IN
cord-264050-6zpw6itb	101	6	HIVinfected	HIVinfected	NNP
cord-264050-6zpw6itb	101	7	and	and	CC
cord-264050-6zpw6itb	101	8	HIV	HIV	NNP
cord-264050-6zpw6itb	101	9	-	-	HYPH
cord-264050-6zpw6itb	101	10	uninfected	uninfected	JJ
cord-264050-6zpw6itb	101	11	patients	patient	NNS
cord-264050-6zpw6itb	101	12	with	with	IN
cord-264050-6zpw6itb	101	13	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	101	14	meningitis	meningitis	NN
cord-264050-6zpw6itb	101	15	Outcomes	outcome	NNS
cord-264050-6zpw6itb	101	16	of	of	IN
cord-264050-6zpw6itb	101	17	central	central	JJ
cord-264050-6zpw6itb	101	18	nervous	nervous	JJ
cord-264050-6zpw6itb	101	19	system	system	NN
cord-264050-6zpw6itb	101	20	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	101	21	vary	vary	VBP
cord-264050-6zpw6itb	101	22	with	with	IN
cord-264050-6zpw6itb	101	23	host	host	NN
cord-264050-6zpw6itb	101	24	immune	immune	JJ
cord-264050-6zpw6itb	101	25	function	function	NN
cord-264050-6zpw6itb	101	26	:	:	:
cord-264050-6zpw6itb	101	27	results	result	NNS
cord-264050-6zpw6itb	101	28	from	from	IN
cord-264050-6zpw6itb	101	29	a	a	DT
cord-264050-6zpw6itb	101	30	multi	multi	JJ
cord-264050-6zpw6itb	101	31	-	-	JJ
cord-264050-6zpw6itb	101	32	center	center	JJ
cord-264050-6zpw6itb	101	33	,	,	,
cord-264050-6zpw6itb	101	34	prospective	prospective	JJ
cord-264050-6zpw6itb	101	35	study	study	NN
cord-264050-6zpw6itb	101	36	Effects	effect	NNS
cord-264050-6zpw6itb	101	37	of	of	IN
cord-264050-6zpw6itb	101	38	the	the	DT
cord-264050-6zpw6itb	101	39	capsular	capsular	JJ
cord-264050-6zpw6itb	101	40	polysaccharides	polysaccharide	NNS
cord-264050-6zpw6itb	101	41	of	of	IN
cord-264050-6zpw6itb	101	42	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	101	43	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	101	44	on	on	IN
cord-264050-6zpw6itb	101	45	phagocyte	phagocyte	NNP
cord-264050-6zpw6itb	101	46	migration	migration	NN
cord-264050-6zpw6itb	101	47	and	and	CC
cord-264050-6zpw6itb	101	48	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	101	49	mediators	mediator	NNS
cord-264050-6zpw6itb	102	1	Downregulation	Downregulation	NNP
cord-264050-6zpw6itb	102	2	by	by	IN
cord-264050-6zpw6itb	102	3	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	102	4	polysaccharide	polysaccharide	NN
cord-264050-6zpw6itb	102	5	of	of	IN
cord-264050-6zpw6itb	102	6	tumor	tumor	NN
cord-264050-6zpw6itb	102	7	necrosis	necrosis	NN
cord-264050-6zpw6itb	102	8	factor	factor	NN
cord-264050-6zpw6itb	102	9	alpha	alpha	NN
cord-264050-6zpw6itb	102	10	and	and	CC
cord-264050-6zpw6itb	102	11	interleukin-1	interleukin-1	NN
cord-264050-6zpw6itb	102	12	beta	beta	JJ
cord-264050-6zpw6itb	102	13	secretion	secretion	NN
cord-264050-6zpw6itb	102	14	from	from	IN
cord-264050-6zpw6itb	102	15	human	human	JJ
cord-264050-6zpw6itb	102	16	monocytes	monocyte	NNS
cord-264050-6zpw6itb	102	17	Purified	purify	VBN
cord-264050-6zpw6itb	102	18	capsular	capsular	JJ
cord-264050-6zpw6itb	102	19	polysaccharide	polysaccharide	NN
cord-264050-6zpw6itb	102	20	of	of	IN
cord-264050-6zpw6itb	102	21	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	102	22	neoformans	neoformans	NNP
cord-264050-6zpw6itb	102	23	induces	induce	VBZ
cord-264050-6zpw6itb	102	24	interleukin-10	interleukin-10	NN
cord-264050-6zpw6itb	102	25	secretion	secretion	NN
cord-264050-6zpw6itb	102	26	by	by	IN
cord-264050-6zpw6itb	102	27	human	human	JJ
cord-264050-6zpw6itb	102	28	monocytes	monocyte	NNS
cord-264050-6zpw6itb	103	1	An	an	DT
cord-264050-6zpw6itb	103	2	immune	immune	JJ
cord-264050-6zpw6itb	103	3	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	103	4	syndrome	syndrome	NN
cord-264050-6zpw6itb	103	5	-	-	HYPH
cord-264050-6zpw6itb	103	6	like	like	JJ
cord-264050-6zpw6itb	103	7	illness	illness	NN
cord-264050-6zpw6itb	103	8	associated	associate	VBN
cord-264050-6zpw6itb	103	9	with	with	IN
cord-264050-6zpw6itb	103	10	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	103	11	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	103	12	infection	infection	NN
cord-264050-6zpw6itb	103	13	in	in	IN
cord-264050-6zpw6itb	103	14	organ	organ	NN
cord-264050-6zpw6itb	103	15	transplant	transplant	NN
cord-264050-6zpw6itb	103	16	recipients	recipient	NNS
cord-264050-6zpw6itb	103	17	Adjunctive	Adjunctive	NNP
cord-264050-6zpw6itb	103	18	interferon	interferon	NN
cord-264050-6zpw6itb	103	19	-	-	HYPH
cord-264050-6zpw6itb	103	20	gamma	gamma	NN
cord-264050-6zpw6itb	103	21	immunotherapy	immunotherapy	NN
cord-264050-6zpw6itb	103	22	for	for	IN
cord-264050-6zpw6itb	103	23	the	the	DT
cord-264050-6zpw6itb	103	24	treatment	treatment	NN
cord-264050-6zpw6itb	103	25	of	of	IN
cord-264050-6zpw6itb	103	26	HIV	HIV	NNP
cord-264050-6zpw6itb	103	27	-	-	HYPH
cord-264050-6zpw6itb	103	28	associated	associate	VBN
cord-264050-6zpw6itb	103	29	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	103	30	meningitis	meningitis	NN
cord-264050-6zpw6itb	103	31	:	:	:
cord-264050-6zpw6itb	103	32	a	a	DT
cord-264050-6zpw6itb	103	33	randomized	randomized	JJ
cord-264050-6zpw6itb	103	34	controlled	control	VBN
cord-264050-6zpw6itb	103	35	trial	trial	NN
cord-264050-6zpw6itb	103	36	Central	central	JJ
cord-264050-6zpw6itb	103	37	nervous	nervous	JJ
cord-264050-6zpw6itb	103	38	system	system	NN
cord-264050-6zpw6itb	103	39	immune	immune	JJ
cord-264050-6zpw6itb	103	40	reconstitution	reconstitution	NN
cord-264050-6zpw6itb	103	41	inflammatory	inflammatory	JJ
cord-264050-6zpw6itb	103	42	syndrome	syndrome	NN
cord-264050-6zpw6itb	103	43	Naive	Naive	NNP
cord-264050-6zpw6itb	103	44	B	B	NNP
cord-264050-6zpw6itb	103	45	cells	cell	NNS
cord-264050-6zpw6itb	103	46	reduce	reduce	VBP
cord-264050-6zpw6itb	103	47	fungal	fungal	JJ
cord-264050-6zpw6itb	103	48	dissemination	dissemination	NN
cord-264050-6zpw6itb	103	49	in	in	IN
cord-264050-6zpw6itb	103	50	Cryptococcus	Cryptococcus	NNP
cord-264050-6zpw6itb	103	51	neoformans	neoforman	VBZ
cord-264050-6zpw6itb	103	52	infected	infect	VBN
cord-264050-6zpw6itb	104	1	Rag1Ϫ/Ϫ	Rag1Ϫ/Ϫ	NNP
cord-264050-6zpw6itb	104	2	mice	mice	NNP
cord-264050-6zpw6itb	104	3	IgM	IgM	NNP
cord-264050-6zpw6itb	104	4	ϩ	ϩ	NNP
cord-264050-6zpw6itb	104	5	memory	memory	NN
cord-264050-6zpw6itb	104	6	B	B	NNP
cord-264050-6zpw6itb	104	7	cell	cell	NN
cord-264050-6zpw6itb	104	8	expression	expression	NN
cord-264050-6zpw6itb	104	9	predicts	predict	VBZ
cord-264050-6zpw6itb	104	10	HIV	HIV	NNP
cord-264050-6zpw6itb	104	11	-	-	HYPH
cord-264050-6zpw6itb	104	12	associated	associate	VBN
cord-264050-6zpw6itb	104	13	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	104	14	status	status	NN
cord-264050-6zpw6itb	104	15	Susceptibility	susceptibility	NN
cord-264050-6zpw6itb	104	16	to	to	IN
cord-264050-6zpw6itb	104	17	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	104	18	meningoencephalitis	meningoencephalitis	NN
cord-264050-6zpw6itb	104	19	associated	associate	VBN
cord-264050-6zpw6itb	104	20	with	with	IN
cord-264050-6zpw6itb	104	21	idiopathic	idiopathic	JJ
cord-264050-6zpw6itb	104	22	CD4	CD4	NNP
cord-264050-6zpw6itb	104	23	ϩ	ϩ	NNP
cord-264050-6zpw6itb	104	24	lymphopenia	lymphopenia	NNP
cord-264050-6zpw6itb	104	25	and	and	CC
cord-264050-6zpw6itb	104	26	secondary	secondary	JJ
cord-264050-6zpw6itb	104	27	germline	germline	NN
cord-264050-6zpw6itb	104	28	or	or	CC
cord-264050-6zpw6itb	104	29	acquired	acquire	VBN
cord-264050-6zpw6itb	104	30	defects	defect	NNS
cord-264050-6zpw6itb	104	31	Fc	Fc	NNP
cord-264050-6zpw6itb	104	32	gamma	gamma	NN
cord-264050-6zpw6itb	104	33	receptor	receptor	NN
cord-264050-6zpw6itb	104	34	3A	3A	NNP
cord-264050-6zpw6itb	104	35	polymorphism	polymorphism	NN
cord-264050-6zpw6itb	104	36	and	and	CC
cord-264050-6zpw6itb	104	37	risk	risk	NN
cord-264050-6zpw6itb	104	38	for	for	IN
cord-264050-6zpw6itb	104	39	HIV	HIV	NNP
cord-264050-6zpw6itb	104	40	-	-	HYPH
cord-264050-6zpw6itb	104	41	associated	associate	VBN
cord-264050-6zpw6itb	104	42	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	104	43	disease	disease	NN
cord-264050-6zpw6itb	104	44	Study	Study	NNP
cord-264050-6zpw6itb	104	45	of	of	IN
cord-264050-6zpw6itb	104	46	common	common	JJ
cord-264050-6zpw6itb	104	47	functional	functional	JJ
cord-264050-6zpw6itb	104	48	genetic	genetic	JJ
cord-264050-6zpw6itb	104	49	polymorphisms	polymorphism	NNS
cord-264050-6zpw6itb	104	50	of	of	IN
cord-264050-6zpw6itb	104	51	FCGR2A	fcgr2a	NN
cord-264050-6zpw6itb	104	52	,	,	,
cord-264050-6zpw6itb	104	53	3A	3a	NN
cord-264050-6zpw6itb	104	54	and	and	CC
cord-264050-6zpw6itb	104	55	3B	3B	NNP
cord-264050-6zpw6itb	104	56	genes	gene	NNS
cord-264050-6zpw6itb	104	57	and	and	CC
cord-264050-6zpw6itb	104	58	the	the	DT
cord-264050-6zpw6itb	104	59	risk	risk	NN
cord-264050-6zpw6itb	104	60	for	for	IN
cord-264050-6zpw6itb	104	61	cryptococcosis	cryptococcosis	NN
cord-264050-6zpw6itb	104	62	in	in	IN
cord-264050-6zpw6itb	104	63	HIV	HIV	NNP
cord-264050-6zpw6itb	104	64	-	-	HYPH
cord-264050-6zpw6itb	104	65	uninfected	uninfected	JJ
cord-264050-6zpw6itb	104	66	patients	patient	NNS
cord-264050-6zpw6itb	104	67	Anti	Anti	NNP
cord-264050-6zpw6itb	104	68	-	-	NNP
cord-264050-6zpw6itb	104	69	GM	GM	NNP
cord-264050-6zpw6itb	104	70	-	-	HYPH
cord-264050-6zpw6itb	104	71	CSF	csf	NN
cord-264050-6zpw6itb	104	72	autoantibodies	autoantibody	NNS
cord-264050-6zpw6itb	104	73	in	in	IN
cord-264050-6zpw6itb	104	74	patients	patient	NNS
cord-264050-6zpw6itb	104	75	with	with	IN
cord-264050-6zpw6itb	104	76	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	104	77	meningitis	meningitis	NN
cord-264050-6zpw6itb	104	78	Genotypes	Genotypes	NNP
cord-264050-6zpw6itb	104	79	coding	code	VBG
cord-264050-6zpw6itb	104	80	for	for	IN
cord-264050-6zpw6itb	104	81	mannose	mannose	NN
cord-264050-6zpw6itb	104	82	-	-	HYPH
cord-264050-6zpw6itb	104	83	binding	bind	VBG
cord-264050-6zpw6itb	104	84	lectin	lectin	NN
cord-264050-6zpw6itb	104	85	deficiency	deficiency	NN
cord-264050-6zpw6itb	104	86	correlated	correlate	VBN
cord-264050-6zpw6itb	104	87	with	with	IN
cord-264050-6zpw6itb	104	88	cryptococcal	cryptococcal	JJ
cord-264050-6zpw6itb	104	89	meningitis	meningitis	NN
cord-264050-6zpw6itb	104	90	in	in	IN
cord-264050-6zpw6itb	104	91	HIV	HIV	NNP
cord-264050-6zpw6itb	104	92	-	-	HYPH
cord-264050-6zpw6itb	104	93	uninfected	uninfected	JJ
cord-264050-6zpw6itb	104	94	Chinese	chinese	JJ
cord-264050-6zpw6itb	104	95	patients	patient	NNS
cord-264050-6zpw6itb	104	96	L.P.	L.P.	NNP
cord-264050-6zpw6itb	104	97	is	be	VBZ
cord-264050-6zpw6itb	104	98	supported	support	VBN
cord-264050-6zpw6itb	104	99	in	in	IN
cord-264050-6zpw6itb	104	100	part	part	NN
cord-264050-6zpw6itb	104	101	by	by	IN
cord-264050-6zpw6itb	104	102	NIH	NIH	NNP
cord-264050-6zpw6itb	105	1	grant	grant	VB
cord-264050-6zpw6itb	105	2	R01AI97096	R01AI97096	NNP
cord-264050-6zpw6itb	105	3	.	.	.
cord-264050-6zpw6itb	106	1	A.C.	A.C.	NNP
cord-264050-6zpw6itb	106	2	is	be	VBZ
cord-264050-6zpw6itb	106	3	supported	support	VBN
cord-264050-6zpw6itb	106	4	in	in	IN
cord-264050-6zpw6itb	106	5	part	part	NN
cord-264050-6zpw6itb	106	6	by	by	IN
cord-264050-6zpw6itb	106	7	NIH	NIH	NNP
cord-264050-6zpw6itb	106	8	grants	grant	NNS
cord-264050-6zpw6itb	106	9	5R01HL059842	5r01hl059842	CD
cord-264050-6zpw6itb	106	10	,	,	,
cord-264050-6zpw6itb	106	11	5R01AI033774	5r01ai033774	CD
cord-264050-6zpw6itb	106	12	,	,	,
cord-264050-6zpw6itb	106	13	5R37AI033142	5r37ai033142	CD
cord-264050-6zpw6itb	106	14	,	,	,
cord-264050-6zpw6itb	106	15	and	and	CC
cord-264050-6zpw6itb	106	16	5R01AI052733	5r01ai052733	CD
cord-264050-6zpw6itb	106	17	.	.	.