id	sid	tid	token	lemma	pos
cord-032504-tmohg1mj	1	1	key	key	JJ
cord-032504-tmohg1mj	1	2	:	:	:
cord-032504-tmohg1mj	1	3	cord-032504-tmohg1mj	cord-032504-tmohg1mj	CD
cord-032504-tmohg1mj	1	4	authors	author	NNS
cord-032504-tmohg1mj	1	5	:	:	:
cord-032504-tmohg1mj	1	6	Auld	Auld	NNP
cord-032504-tmohg1mj	1	7	,	,	,
cord-032504-tmohg1mj	1	8	Sara	Sara	NNP
cord-032504-tmohg1mj	1	9	C.	C.	NNP
cord-032504-tmohg1mj	1	10	;	;	:
cord-032504-tmohg1mj	2	1	Staitieh	Staitieh	NNP
cord-032504-tmohg1mj	2	2	,	,	,
cord-032504-tmohg1mj	2	3	Bashar	Bashar	NNP
cord-032504-tmohg1mj	2	4	S.	S.	NNP
cord-032504-tmohg1mj	2	5	title	title	NN
cord-032504-tmohg1mj	2	6	:	:	:
cord-032504-tmohg1mj	2	7	HIV	HIV	NNP
cord-032504-tmohg1mj	2	8	and	and	CC
cord-032504-tmohg1mj	2	9	the	the	DT
cord-032504-tmohg1mj	2	10	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	2	11	“	"	``
cord-032504-tmohg1mj	2	12	set	set	NN
cord-032504-tmohg1mj	2	13	point	point	NN
cord-032504-tmohg1mj	2	14	”	"	''
cord-032504-tmohg1mj	2	15	:	:	:
cord-032504-tmohg1mj	3	1	how	how	WRB
cord-032504-tmohg1mj	3	2	HIV	HIV	NNP
cord-032504-tmohg1mj	3	3	impairs	impair	VBZ
cord-032504-tmohg1mj	3	4	alveolar	alveolar	JJ
cord-032504-tmohg1mj	3	5	macrophage	macrophage	NN
cord-032504-tmohg1mj	3	6	responses	response	NNS
cord-032504-tmohg1mj	3	7	to	to	IN
cord-032504-tmohg1mj	3	8	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	3	9	and	and	CC
cord-032504-tmohg1mj	3	10	sets	set	VBZ
cord-032504-tmohg1mj	3	11	the	the	DT
cord-032504-tmohg1mj	3	12	stage	stage	NN
cord-032504-tmohg1mj	3	13	for	for	IN
cord-032504-tmohg1mj	3	14	progressive	progressive	JJ
cord-032504-tmohg1mj	3	15	disease	disease	NN
cord-032504-tmohg1mj	3	16	date	date	NN
cord-032504-tmohg1mj	4	1	:	:	:
cord-032504-tmohg1mj	4	2	2020	2020	CD
cord-032504-tmohg1mj	4	3	-	-	HYPH
cord-032504-tmohg1mj	4	4	09	09	CD
cord-032504-tmohg1mj	4	5	-	-	SYM
cord-032504-tmohg1mj	4	6	23	23	CD
cord-032504-tmohg1mj	4	7	journal	journal	NN
cord-032504-tmohg1mj	4	8	:	:	:
cord-032504-tmohg1mj	5	1	Retrovirology	Retrovirology	NNP
cord-032504-tmohg1mj	5	2	DOI	DOI	NNP
cord-032504-tmohg1mj	5	3	:	:	:
cord-032504-tmohg1mj	5	4	10.1186	10.1186	CD
cord-032504-tmohg1mj	5	5	/	/	SYM
cord-032504-tmohg1mj	5	6	s12977	s12977	NNP
cord-032504-tmohg1mj	6	1	-020	-020	NN
cord-032504-tmohg1mj	6	2	-	-	HYPH
cord-032504-tmohg1mj	6	3	00540	00540	CD
cord-032504-tmohg1mj	6	4	-	-	SYM
cord-032504-tmohg1mj	6	5	2	2	CD
cord-032504-tmohg1mj	6	6	sha	sha	NN
cord-032504-tmohg1mj	6	7	:	:	:
cord-032504-tmohg1mj	6	8	28e4f0d5b1508bec5283f97801129de71eb03adf	28e4f0d5b1508bec5283f97801129de71eb03adf	NFP
cord-032504-tmohg1mj	6	9	doc_id	doc_id	CD
cord-032504-tmohg1mj	6	10	:	:	:
cord-032504-tmohg1mj	6	11	32504	32504	CD
cord-032504-tmohg1mj	6	12	cord_uid	cord_uid	NNS
cord-032504-tmohg1mj	6	13	:	:	:
cord-032504-tmohg1mj	6	14	tmohg1mj	tmohg1mj	NNS
cord-032504-tmohg1mj	7	1	As	as	IN
cord-032504-tmohg1mj	7	2	HIV	HIV	NNP
cord-032504-tmohg1mj	7	3	has	have	VBZ
cord-032504-tmohg1mj	7	4	fueled	fuel	VBN
cord-032504-tmohg1mj	7	5	a	a	DT
cord-032504-tmohg1mj	7	6	global	global	JJ
cord-032504-tmohg1mj	7	7	resurgence	resurgence	NN
cord-032504-tmohg1mj	7	8	of	of	IN
cord-032504-tmohg1mj	7	9	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	7	10	over	over	IN
cord-032504-tmohg1mj	7	11	the	the	DT
cord-032504-tmohg1mj	7	12	last	last	JJ
cord-032504-tmohg1mj	7	13	several	several	JJ
cord-032504-tmohg1mj	7	14	decades	decade	NNS
cord-032504-tmohg1mj	7	15	,	,	,
cord-032504-tmohg1mj	7	16	there	there	EX
cord-032504-tmohg1mj	7	17	is	be	VBZ
cord-032504-tmohg1mj	7	18	a	a	DT
cord-032504-tmohg1mj	7	19	growing	grow	VBG
cord-032504-tmohg1mj	7	20	awareness	awareness	NN
cord-032504-tmohg1mj	7	21	that	that	WDT
cord-032504-tmohg1mj	7	22	HIV	HIV	NNP
cord-032504-tmohg1mj	7	23	-	-	HYPH
cord-032504-tmohg1mj	7	24	mediated	mediate	VBN
cord-032504-tmohg1mj	7	25	impairments	impairment	NNS
cord-032504-tmohg1mj	7	26	in	in	IN
cord-032504-tmohg1mj	7	27	both	both	DT
cord-032504-tmohg1mj	7	28	innate	innate	JJ
cord-032504-tmohg1mj	7	29	and	and	CC
cord-032504-tmohg1mj	7	30	adaptive	adaptive	JJ
cord-032504-tmohg1mj	7	31	immunity	immunity	NN
cord-032504-tmohg1mj	7	32	contribute	contribute	VBP
cord-032504-tmohg1mj	7	33	to	to	IN
cord-032504-tmohg1mj	7	34	the	the	DT
cord-032504-tmohg1mj	7	35	heightened	heightened	JJ
cord-032504-tmohg1mj	7	36	risk	risk	NN
cord-032504-tmohg1mj	7	37	of	of	IN
cord-032504-tmohg1mj	7	38	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	7	39	in	in	IN
cord-032504-tmohg1mj	7	40	people	people	NNS
cord-032504-tmohg1mj	7	41	with	with	IN
cord-032504-tmohg1mj	7	42	HIV	HIV	NNP
cord-032504-tmohg1mj	7	43	.	.	.
cord-032504-tmohg1mj	8	1	Since	since	IN
cord-032504-tmohg1mj	8	2	early	early	JJ
cord-032504-tmohg1mj	8	3	immune	immune	JJ
cord-032504-tmohg1mj	8	4	responses	response	NNS
cord-032504-tmohg1mj	8	5	to	to	IN
cord-032504-tmohg1mj	8	6	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	8	7	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	8	8	(	(	-LRB-
cord-032504-tmohg1mj	8	9	Mtb	Mtb	NNP
cord-032504-tmohg1mj	8	10	)	)	-RRB-
cord-032504-tmohg1mj	8	11	set	set	VBD
cord-032504-tmohg1mj	8	12	the	the	DT
cord-032504-tmohg1mj	8	13	stage	stage	NN
cord-032504-tmohg1mj	8	14	for	for	IN
cord-032504-tmohg1mj	8	15	subsequent	subsequent	JJ
cord-032504-tmohg1mj	8	16	control	control	NN
cord-032504-tmohg1mj	8	17	or	or	CC
cord-032504-tmohg1mj	8	18	progression	progression	NN
cord-032504-tmohg1mj	8	19	to	to	IN
cord-032504-tmohg1mj	8	20	active	active	JJ
cord-032504-tmohg1mj	8	21	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	8	22	disease	disease	NN
cord-032504-tmohg1mj	8	23	,	,	,
cord-032504-tmohg1mj	8	24	early	early	JJ
cord-032504-tmohg1mj	8	25	host	host	NN
cord-032504-tmohg1mj	8	26	–	–	:
cord-032504-tmohg1mj	8	27	pathogen	pathogen	NN
cord-032504-tmohg1mj	8	28	interactions	interaction	NNS
cord-032504-tmohg1mj	8	29	following	follow	VBG
cord-032504-tmohg1mj	8	30	Mtb	Mtb	NNP
cord-032504-tmohg1mj	8	31	infection	infection	NN
cord-032504-tmohg1mj	8	32	can	can	MD
cord-032504-tmohg1mj	8	33	be	be	VB
cord-032504-tmohg1mj	8	34	thought	think	VBN
cord-032504-tmohg1mj	8	35	of	of	IN
cord-032504-tmohg1mj	8	36	as	as	IN
cord-032504-tmohg1mj	8	37	establishing	establish	VBG
cord-032504-tmohg1mj	8	38	a	a	DT
cord-032504-tmohg1mj	8	39	mycobacterial	mycobacterial	NN
cord-032504-tmohg1mj	8	40	“	"	``
cord-032504-tmohg1mj	8	41	set	set	NN
cord-032504-tmohg1mj	8	42	point	point	NN
cord-032504-tmohg1mj	8	43	,	,	,
cord-032504-tmohg1mj	8	44	”	"	''
cord-032504-tmohg1mj	8	45	which	which	WDT
cord-032504-tmohg1mj	8	46	we	-PRON-	PRP
cord-032504-tmohg1mj	8	47	define	define	VBP
cord-032504-tmohg1mj	8	48	as	as	IN
cord-032504-tmohg1mj	8	49	the	the	DT
cord-032504-tmohg1mj	8	50	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	8	51	burden	burden	NN
cord-032504-tmohg1mj	8	52	at	at	IN
cord-032504-tmohg1mj	8	53	the	the	DT
cord-032504-tmohg1mj	8	54	point	point	NN
cord-032504-tmohg1mj	8	55	of	of	IN
cord-032504-tmohg1mj	8	56	adaptive	adaptive	JJ
cord-032504-tmohg1mj	8	57	immune	immune	JJ
cord-032504-tmohg1mj	8	58	activation	activation	NN
cord-032504-tmohg1mj	8	59	.	.	.
cord-032504-tmohg1mj	9	1	This	this	DT
cord-032504-tmohg1mj	9	2	early	early	JJ
cord-032504-tmohg1mj	9	3	immune	immune	JJ
cord-032504-tmohg1mj	9	4	response	response	NN
cord-032504-tmohg1mj	9	5	is	be	VBZ
cord-032504-tmohg1mj	9	6	impaired	impair	VBN
cord-032504-tmohg1mj	9	7	in	in	IN
cord-032504-tmohg1mj	9	8	the	the	DT
cord-032504-tmohg1mj	9	9	context	context	NN
cord-032504-tmohg1mj	9	10	of	of	IN
cord-032504-tmohg1mj	9	11	HIV	HIV	NNP
cord-032504-tmohg1mj	9	12	coinfection	coinfection	NN
cord-032504-tmohg1mj	9	13	,	,	,
cord-032504-tmohg1mj	9	14	allowing	allow	VBG
cord-032504-tmohg1mj	9	15	for	for	IN
cord-032504-tmohg1mj	9	16	a	a	DT
cord-032504-tmohg1mj	9	17	higher	high	JJR
cord-032504-tmohg1mj	9	18	mycobacterial	mycobacterial	NN
cord-032504-tmohg1mj	9	19	set	set	NN
cord-032504-tmohg1mj	9	20	point	point	NN
cord-032504-tmohg1mj	9	21	and	and	CC
cord-032504-tmohg1mj	9	22	greater	great	JJR
cord-032504-tmohg1mj	9	23	likelihood	likelihood	NN
cord-032504-tmohg1mj	9	24	of	of	IN
cord-032504-tmohg1mj	9	25	progression	progression	NN
cord-032504-tmohg1mj	9	26	to	to	IN
cord-032504-tmohg1mj	9	27	active	active	JJ
cord-032504-tmohg1mj	9	28	disease	disease	NN
cord-032504-tmohg1mj	9	29	with	with	IN
cord-032504-tmohg1mj	9	30	greater	great	JJR
cord-032504-tmohg1mj	9	31	bacterial	bacterial	JJ
cord-032504-tmohg1mj	9	32	burden	burden	NN
cord-032504-tmohg1mj	9	33	.	.	.
cord-032504-tmohg1mj	10	1	Alveolar	alveolar	NN
cord-032504-tmohg1mj	10	2	macrophages	macrophage	NNS
cord-032504-tmohg1mj	10	3	,	,	,
cord-032504-tmohg1mj	10	4	as	as	IN
cord-032504-tmohg1mj	10	5	the	the	DT
cord-032504-tmohg1mj	10	6	first	first	JJ
cord-032504-tmohg1mj	10	7	cells	cell	NNS
cord-032504-tmohg1mj	10	8	to	to	TO
cord-032504-tmohg1mj	10	9	encounter	encounter	VB
cord-032504-tmohg1mj	10	10	Mtb	Mtb	NNP
cord-032504-tmohg1mj	10	11	in	in	IN
cord-032504-tmohg1mj	10	12	the	the	DT
cord-032504-tmohg1mj	10	13	lungs	lung	NNS
cord-032504-tmohg1mj	10	14	,	,	,
cord-032504-tmohg1mj	10	15	play	play	VB
cord-032504-tmohg1mj	10	16	a	a	DT
cord-032504-tmohg1mj	10	17	critical	critical	JJ
cord-032504-tmohg1mj	10	18	role	role	NN
cord-032504-tmohg1mj	10	19	in	in	IN
cord-032504-tmohg1mj	10	20	containing	contain	VBG
cord-032504-tmohg1mj	10	21	Mtb	Mtb	NNP
cord-032504-tmohg1mj	10	22	growth	growth	NN
cord-032504-tmohg1mj	10	23	and	and	CC
cord-032504-tmohg1mj	10	24	establishing	establish	VBG
cord-032504-tmohg1mj	10	25	the	the	DT
cord-032504-tmohg1mj	10	26	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	10	27	set	set	NN
cord-032504-tmohg1mj	10	28	point	point	NN
cord-032504-tmohg1mj	10	29	.	.	.
cord-032504-tmohg1mj	11	1	However	however	RB
cord-032504-tmohg1mj	11	2	,	,	,
cord-032504-tmohg1mj	11	3	a	a	DT
cord-032504-tmohg1mj	11	4	number	number	NN
cord-032504-tmohg1mj	11	5	of	of	IN
cord-032504-tmohg1mj	11	6	key	key	JJ
cord-032504-tmohg1mj	11	7	macrophage	macrophage	NN
cord-032504-tmohg1mj	11	8	functions	function	NNS
cord-032504-tmohg1mj	11	9	,	,	,
cord-032504-tmohg1mj	11	10	ranging	range	VBG
cord-032504-tmohg1mj	11	11	from	from	IN
cord-032504-tmohg1mj	11	12	pathogen	pathogen	NN
cord-032504-tmohg1mj	11	13	recognition	recognition	NN
cord-032504-tmohg1mj	11	14	and	and	CC
cord-032504-tmohg1mj	11	15	uptake	uptake	NN
cord-032504-tmohg1mj	11	16	to	to	IN
cord-032504-tmohg1mj	11	17	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	11	18	and	and	CC
cord-032504-tmohg1mj	11	19	microbial	microbial	JJ
cord-032504-tmohg1mj	11	20	killing	killing	NN
cord-032504-tmohg1mj	11	21	,	,	,
cord-032504-tmohg1mj	11	22	are	be	VBP
cord-032504-tmohg1mj	11	23	blunted	blunt	VBN
cord-032504-tmohg1mj	11	24	in	in	IN
cord-032504-tmohg1mj	11	25	HIV	HIV	NNP
cord-032504-tmohg1mj	11	26	coinfection	coinfection	NN
cord-032504-tmohg1mj	11	27	.	.	.
cord-032504-tmohg1mj	12	1	To	to	IN
cord-032504-tmohg1mj	12	2	date	date	NN
cord-032504-tmohg1mj	12	3	,	,	,
cord-032504-tmohg1mj	12	4	research	research	NN
cord-032504-tmohg1mj	12	5	evaluating	evaluate	VBG
cord-032504-tmohg1mj	12	6	the	the	DT
cord-032504-tmohg1mj	12	7	effects	effect	NNS
cord-032504-tmohg1mj	12	8	of	of	IN
cord-032504-tmohg1mj	12	9	HIV	HIV	NNP
cord-032504-tmohg1mj	12	10	on	on	IN
cord-032504-tmohg1mj	12	11	the	the	DT
cord-032504-tmohg1mj	12	12	alveolar	alveolar	JJ
cord-032504-tmohg1mj	12	13	macrophage	macrophage	NN
cord-032504-tmohg1mj	12	14	response	response	NN
cord-032504-tmohg1mj	12	15	to	to	IN
cord-032504-tmohg1mj	12	16	Mtb	Mtb	NNP
cord-032504-tmohg1mj	12	17	has	have	VBZ
cord-032504-tmohg1mj	12	18	been	be	VBN
cord-032504-tmohg1mj	12	19	relatively	relatively	RB
cord-032504-tmohg1mj	12	20	limited	limit	VBN
cord-032504-tmohg1mj	12	21	,	,	,
cord-032504-tmohg1mj	12	22	particularly	particularly	RB
cord-032504-tmohg1mj	12	23	with	with	IN
cord-032504-tmohg1mj	12	24	regard	regard	NN
cord-032504-tmohg1mj	12	25	to	to	IN
cord-032504-tmohg1mj	12	26	the	the	DT
cord-032504-tmohg1mj	12	27	critical	critical	JJ
cord-032504-tmohg1mj	12	28	early	early	JJ
cord-032504-tmohg1mj	12	29	events	event	NNS
cord-032504-tmohg1mj	12	30	that	that	WDT
cord-032504-tmohg1mj	12	31	help	help	VBP
cord-032504-tmohg1mj	12	32	to	to	TO
cord-032504-tmohg1mj	12	33	dictate	dictate	VB
cord-032504-tmohg1mj	12	34	the	the	DT
cord-032504-tmohg1mj	12	35	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	12	36	set	set	NNP
cord-032504-tmohg1mj	12	37	point	point	NN
cord-032504-tmohg1mj	12	38	.	.	.
cord-032504-tmohg1mj	13	1	A	a	DT
cord-032504-tmohg1mj	13	2	greater	great	JJR
cord-032504-tmohg1mj	13	3	understanding	understanding	NN
cord-032504-tmohg1mj	13	4	of	of	IN
cord-032504-tmohg1mj	13	5	alveolar	alveolar	JJ
cord-032504-tmohg1mj	13	6	macrophage	macrophage	NN
cord-032504-tmohg1mj	13	7	functions	function	NNS
cord-032504-tmohg1mj	13	8	impacted	impact	VBN
cord-032504-tmohg1mj	13	9	by	by	IN
cord-032504-tmohg1mj	13	10	HIV	HIV	NNP
cord-032504-tmohg1mj	13	11	coinfection	coinfection	NN
cord-032504-tmohg1mj	13	12	will	will	MD
cord-032504-tmohg1mj	13	13	improve	improve	VB
cord-032504-tmohg1mj	13	14	our	-PRON-	PRP$
cord-032504-tmohg1mj	13	15	understanding	understanding	NN
cord-032504-tmohg1mj	13	16	of	of	IN
cord-032504-tmohg1mj	13	17	protective	protective	JJ
cord-032504-tmohg1mj	13	18	immunity	immunity	NN
cord-032504-tmohg1mj	13	19	to	to	IN
cord-032504-tmohg1mj	13	20	Mtb	Mtb	NNP
cord-032504-tmohg1mj	13	21	and	and	CC
cord-032504-tmohg1mj	13	22	may	may	MD
cord-032504-tmohg1mj	13	23	reveal	reveal	VB
cord-032504-tmohg1mj	13	24	novel	novel	JJ
cord-032504-tmohg1mj	13	25	pathways	pathway	NNS
cord-032504-tmohg1mj	13	26	amenable	amenable	JJ
cord-032504-tmohg1mj	13	27	to	to	IN
cord-032504-tmohg1mj	13	28	intervention	intervention	NN
cord-032504-tmohg1mj	13	29	to	to	TO
cord-032504-tmohg1mj	13	30	improve	improve	VB
cord-032504-tmohg1mj	13	31	both	both	DT
cord-032504-tmohg1mj	13	32	early	early	JJ
cord-032504-tmohg1mj	13	33	immune	immune	JJ
cord-032504-tmohg1mj	13	34	control	control	NN
cord-032504-tmohg1mj	13	35	of	of	IN
cord-032504-tmohg1mj	13	36	Mtb	Mtb	NNP
cord-032504-tmohg1mj	13	37	and	and	CC
cord-032504-tmohg1mj	13	38	clinical	clinical	JJ
cord-032504-tmohg1mj	13	39	outcomes	outcome	NNS
cord-032504-tmohg1mj	13	40	for	for	IN
cord-032504-tmohg1mj	13	41	the	the	DT
cord-032504-tmohg1mj	13	42	millions	million	NNS
cord-032504-tmohg1mj	13	43	of	of	IN
cord-032504-tmohg1mj	13	44	people	people	NNS
cord-032504-tmohg1mj	13	45	worldwide	worldwide	RB
cord-032504-tmohg1mj	13	46	infected	infect	VBN
cord-032504-tmohg1mj	13	47	with	with	IN
cord-032504-tmohg1mj	13	48	HIV	HIV	NNP
cord-032504-tmohg1mj	13	49	.	.	.
cord-032504-tmohg1mj	14	1	Although	although	IN
cord-032504-tmohg1mj	14	2	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	14	3	incidence	incidence	NN
cord-032504-tmohg1mj	14	4	declined	decline	VBD
cord-032504-tmohg1mj	14	5	worldwide	worldwide	RB
cord-032504-tmohg1mj	14	6	over	over	IN
cord-032504-tmohg1mj	14	7	the	the	DT
cord-032504-tmohg1mj	14	8	course	course	NN
cord-032504-tmohg1mj	14	9	of	of	IN
cord-032504-tmohg1mj	14	10	the	the	DT
cord-032504-tmohg1mj	14	11	20	20	CD
cord-032504-tmohg1mj	14	12	th	th	XX
cord-032504-tmohg1mj	14	13	century	century	NN
cord-032504-tmohg1mj	14	14	[	[	-LRB-
cord-032504-tmohg1mj	14	15	1	1	CD
cord-032504-tmohg1mj	14	16	]	]	-RRB-
cord-032504-tmohg1mj	14	17	[	[	-LRB-
cord-032504-tmohg1mj	14	18	2	2	CD
cord-032504-tmohg1mj	14	19	]	]	-RRB-
cord-032504-tmohg1mj	14	20	[	[	-LRB-
cord-032504-tmohg1mj	14	21	3	3	CD
cord-032504-tmohg1mj	14	22	]	]	-RRB-
cord-032504-tmohg1mj	14	23	[	[	-LRB-
cord-032504-tmohg1mj	14	24	4	4	CD
cord-032504-tmohg1mj	14	25	]	]	-RRB-
cord-032504-tmohg1mj	14	26	,	,	,
cord-032504-tmohg1mj	14	27	these	these	DT
cord-032504-tmohg1mj	14	28	gains	gain	NNS
cord-032504-tmohg1mj	14	29	were	be	VBD
cord-032504-tmohg1mj	14	30	quickly	quickly	RB
cord-032504-tmohg1mj	14	31	reversed	reverse	VBN
cord-032504-tmohg1mj	14	32	with	with	IN
cord-032504-tmohg1mj	14	33	the	the	DT
cord-032504-tmohg1mj	14	34	onset	onset	NN
cord-032504-tmohg1mj	14	35	of	of	IN
cord-032504-tmohg1mj	14	36	the	the	DT
cord-032504-tmohg1mj	14	37	HIV	HIV	NNP
cord-032504-tmohg1mj	14	38	epidemic	epidemic	NN
cord-032504-tmohg1mj	14	39	in	in	IN
cord-032504-tmohg1mj	14	40	the	the	DT
cord-032504-tmohg1mj	14	41	1980s	1980	NNS
cord-032504-tmohg1mj	14	42	[	[	-LRB-
cord-032504-tmohg1mj	14	43	5	5	CD
cord-032504-tmohg1mj	14	44	]	]	-RRB-
cord-032504-tmohg1mj	14	45	.	.	.
cord-032504-tmohg1mj	15	1	Tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	15	2	is	be	VBZ
cord-032504-tmohg1mj	15	3	now	now	RB
cord-032504-tmohg1mj	15	4	the	the	DT
cord-032504-tmohg1mj	15	5	leading	lead	VBG
cord-032504-tmohg1mj	15	6	global	global	JJ
cord-032504-tmohg1mj	15	7	killer	killer	NN
cord-032504-tmohg1mj	15	8	among	among	IN
cord-032504-tmohg1mj	15	9	infectious	infectious	JJ
cord-032504-tmohg1mj	15	10	diseases	disease	NNS
cord-032504-tmohg1mj	15	11	and	and	CC
cord-032504-tmohg1mj	15	12	the	the	DT
cord-032504-tmohg1mj	15	13	leading	leading	JJ
cord-032504-tmohg1mj	15	14	cause	cause	NN
cord-032504-tmohg1mj	15	15	of	of	IN
cord-032504-tmohg1mj	15	16	death	death	NN
cord-032504-tmohg1mj	15	17	among	among	IN
cord-032504-tmohg1mj	15	18	people	people	NNS
cord-032504-tmohg1mj	15	19	with	with	IN
cord-032504-tmohg1mj	15	20	HIV	HIV	NNP
cord-032504-tmohg1mj	15	21	[	[	-LRB-
cord-032504-tmohg1mj	15	22	6	6	CD
cord-032504-tmohg1mj	15	23	]	]	-RRB-
cord-032504-tmohg1mj	15	24	.	.	.
cord-032504-tmohg1mj	16	1	The	the	DT
cord-032504-tmohg1mj	16	2	profound	profound	JJ
cord-032504-tmohg1mj	16	3	T	t	NN
cord-032504-tmohg1mj	16	4	cell	cell	NN
cord-032504-tmohg1mj	16	5	depletion	depletion	NN
cord-032504-tmohg1mj	16	6	induced	induce	VBN
cord-032504-tmohg1mj	16	7	by	by	IN
cord-032504-tmohg1mj	16	8	HIV	HIV	NNP
cord-032504-tmohg1mj	16	9	has	have	VBZ
cord-032504-tmohg1mj	16	10	long	long	RB
cord-032504-tmohg1mj	16	11	been	be	VBN
cord-032504-tmohg1mj	16	12	recognized	recognize	VBN
cord-032504-tmohg1mj	16	13	as	as	IN
cord-032504-tmohg1mj	16	14	a	a	DT
cord-032504-tmohg1mj	16	15	significant	significant	JJ
cord-032504-tmohg1mj	16	16	driver	driver	NN
cord-032504-tmohg1mj	16	17	of	of	IN
cord-032504-tmohg1mj	16	18	the	the	DT
cord-032504-tmohg1mj	16	19	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	16	20	epidemic	epidemic	NN
cord-032504-tmohg1mj	16	21	in	in	IN
cord-032504-tmohg1mj	16	22	people	people	NNS
cord-032504-tmohg1mj	16	23	with	with	IN
cord-032504-tmohg1mj	16	24	HIV	HIV	NNP
cord-032504-tmohg1mj	16	25	[	[	-LRB-
cord-032504-tmohg1mj	16	26	7	7	CD
cord-032504-tmohg1mj	16	27	,	,	,
cord-032504-tmohg1mj	16	28	8	8	CD
cord-032504-tmohg1mj	16	29	]	]	-RRB-
cord-032504-tmohg1mj	16	30	.	.	.
cord-032504-tmohg1mj	17	1	However	however	RB
cord-032504-tmohg1mj	17	2	,	,	,
cord-032504-tmohg1mj	17	3	there	there	EX
cord-032504-tmohg1mj	17	4	is	be	VBZ
cord-032504-tmohg1mj	17	5	growing	grow	VBG
cord-032504-tmohg1mj	17	6	awareness	awareness	NN
cord-032504-tmohg1mj	17	7	that	that	WDT
cord-032504-tmohg1mj	17	8	HIV	HIV	NNP
cord-032504-tmohg1mj	17	9	-	-	HYPH
cord-032504-tmohg1mj	17	10	mediated	mediate	VBN
cord-032504-tmohg1mj	17	11	impairments	impairment	NNS
cord-032504-tmohg1mj	17	12	in	in	IN
cord-032504-tmohg1mj	17	13	innate	innate	JJ
cord-032504-tmohg1mj	17	14	immunity	immunity	NN
cord-032504-tmohg1mj	17	15	also	also	RB
cord-032504-tmohg1mj	17	16	contribute	contribute	VBP
cord-032504-tmohg1mj	17	17	to	to	IN
cord-032504-tmohg1mj	17	18	the	the	DT
cord-032504-tmohg1mj	17	19	increased	increase	VBN
cord-032504-tmohg1mj	17	20	risk	risk	NN
cord-032504-tmohg1mj	17	21	of	of	IN
cord-032504-tmohg1mj	17	22	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	17	23	in	in	IN
cord-032504-tmohg1mj	17	24	this	this	DT
cord-032504-tmohg1mj	17	25	vulnerable	vulnerable	JJ
cord-032504-tmohg1mj	17	26	population	population	NN
cord-032504-tmohg1mj	17	27	.	.	.
cord-032504-tmohg1mj	18	1	These	these	DT
cord-032504-tmohg1mj	18	2	HIV	HIV	NNP
cord-032504-tmohg1mj	18	3	-	-	HYPH
cord-032504-tmohg1mj	18	4	mediated	mediate	VBN
cord-032504-tmohg1mj	18	5	impairments	impairment	NNS
cord-032504-tmohg1mj	18	6	in	in	IN
cord-032504-tmohg1mj	18	7	innate	innate	JJ
cord-032504-tmohg1mj	18	8	immunity	immunity	NN
cord-032504-tmohg1mj	18	9	are	be	VBP
cord-032504-tmohg1mj	18	10	particularly	particularly	RB
cord-032504-tmohg1mj	18	11	relevant	relevant	JJ
cord-032504-tmohg1mj	18	12	early	early	RB
cord-032504-tmohg1mj	18	13	in	in	IN
cord-032504-tmohg1mj	18	14	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	18	15	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	18	16	(	(	-LRB-
cord-032504-tmohg1mj	18	17	Mtb	Mtb	NNP
cord-032504-tmohg1mj	18	18	)	)	-RRB-
cord-032504-tmohg1mj	18	19	infection	infection	NN
cord-032504-tmohg1mj	18	20	,	,	,
cord-032504-tmohg1mj	18	21	prior	prior	RB
cord-032504-tmohg1mj	18	22	to	to	IN
cord-032504-tmohg1mj	18	23	the	the	DT
cord-032504-tmohg1mj	18	24	onset	onset	NN
cord-032504-tmohg1mj	18	25	of	of	IN
cord-032504-tmohg1mj	18	26	adaptive	adaptive	JJ
cord-032504-tmohg1mj	18	27	immune	immune	JJ
cord-032504-tmohg1mj	18	28	responses	response	NNS
cord-032504-tmohg1mj	18	29	[	[	-LRB-
cord-032504-tmohg1mj	18	30	9	9	CD
cord-032504-tmohg1mj	18	31	]	]	-RRB-
cord-032504-tmohg1mj	18	32	and	and	CC
cord-032504-tmohg1mj	18	33	,	,	,
cord-032504-tmohg1mj	18	34	by	by	IN
cord-032504-tmohg1mj	18	35	impairing	impair	VBG
cord-032504-tmohg1mj	18	36	early	early	JJ
cord-032504-tmohg1mj	18	37	control	control	NN
cord-032504-tmohg1mj	18	38	of	of	IN
cord-032504-tmohg1mj	18	39	Mtb	Mtb	NNP
cord-032504-tmohg1mj	18	40	,	,	,
cord-032504-tmohg1mj	18	41	set	set	VBD
cord-032504-tmohg1mj	18	42	the	the	DT
cord-032504-tmohg1mj	18	43	stage	stage	NN
cord-032504-tmohg1mj	18	44	for	for	IN
cord-032504-tmohg1mj	18	45	accelerated	accelerated	JJ
cord-032504-tmohg1mj	18	46	progression	progression	NN
cord-032504-tmohg1mj	18	47	to	to	IN
cord-032504-tmohg1mj	18	48	active	active	JJ
cord-032504-tmohg1mj	18	49	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	18	50	disease	disease	NN
cord-032504-tmohg1mj	18	51	.	.	.
cord-032504-tmohg1mj	19	1	The	the	DT
cord-032504-tmohg1mj	19	2	pattern	pattern	NN
cord-032504-tmohg1mj	19	3	of	of	IN
cord-032504-tmohg1mj	19	4	early	early	JJ
cord-032504-tmohg1mj	19	5	immune	immune	JJ
cord-032504-tmohg1mj	19	6	control	control	NN
cord-032504-tmohg1mj	19	7	setting	set	VBG
cord-032504-tmohg1mj	19	8	the	the	DT
cord-032504-tmohg1mj	19	9	stage	stage	NN
cord-032504-tmohg1mj	19	10	for	for	IN
cord-032504-tmohg1mj	19	11	longer	long	JJR
cord-032504-tmohg1mj	19	12	term	term	NN
cord-032504-tmohg1mj	19	13	control	control	NN
cord-032504-tmohg1mj	19	14	-	-	:
cord-032504-tmohg1mj	19	15	and	and	CC
cord-032504-tmohg1mj	19	16	clinically	clinically	RB
cord-032504-tmohg1mj	19	17	meaningful	meaningful	JJ
cord-032504-tmohg1mj	19	18	endpoints	endpoint	NNS
cord-032504-tmohg1mj	19	19	-	-	:
cord-032504-tmohg1mj	19	20	parallels	parallel	VBZ
cord-032504-tmohg1mj	19	21	our	-PRON-	PRP$
cord-032504-tmohg1mj	19	22	understanding	understanding	NN
cord-032504-tmohg1mj	19	23	of	of	IN
cord-032504-tmohg1mj	19	24	the	the	DT
cord-032504-tmohg1mj	19	25	HIV	HIV	NNP
cord-032504-tmohg1mj	19	26	set	set	NN
cord-032504-tmohg1mj	19	27	point	point	NN
cord-032504-tmohg1mj	19	28	.	.	.
cord-032504-tmohg1mj	20	1	It	-PRON-	PRP
cord-032504-tmohg1mj	20	2	was	be	VBD
cord-032504-tmohg1mj	20	3	first	first	RB
cord-032504-tmohg1mj	20	4	recognized	recognize	VBN
cord-032504-tmohg1mj	20	5	in	in	IN
cord-032504-tmohg1mj	20	6	the	the	DT
cord-032504-tmohg1mj	20	7	late	late	JJ
cord-032504-tmohg1mj	20	8	1990s	1990	NNS
cord-032504-tmohg1mj	20	9	that	that	IN
cord-032504-tmohg1mj	20	10	the	the	DT
cord-032504-tmohg1mj	20	11	HIV	HIV	NNP
cord-032504-tmohg1mj	20	12	viral	viral	JJ
cord-032504-tmohg1mj	20	13	load	load	NN
cord-032504-tmohg1mj	20	14	soon	soon	RB
cord-032504-tmohg1mj	20	15	after	after	IN
cord-032504-tmohg1mj	20	16	seroconversion	seroconversion	NN
cord-032504-tmohg1mj	20	17	,	,	,
cord-032504-tmohg1mj	20	18	i.e.	i.e.	FW
cord-032504-tmohg1mj	20	19	,	,	,
cord-032504-tmohg1mj	20	20	the	the	DT
cord-032504-tmohg1mj	20	21	HIV	HIV	NNP
cord-032504-tmohg1mj	20	22	set	set	NN
cord-032504-tmohg1mj	20	23	point	point	NN
cord-032504-tmohg1mj	20	24	,	,	,
cord-032504-tmohg1mj	20	25	is	be	VBZ
cord-032504-tmohg1mj	20	26	predictive	predictive	JJ
cord-032504-tmohg1mj	20	27	of	of	IN
cord-032504-tmohg1mj	20	28	disease	disease	NN
cord-032504-tmohg1mj	20	29	progression	progression	NN
cord-032504-tmohg1mj	20	30	[	[	-LRB-
cord-032504-tmohg1mj	20	31	10	10	CD
cord-032504-tmohg1mj	20	32	,	,	,
cord-032504-tmohg1mj	20	33	11	11	CD
cord-032504-tmohg1mj	20	34	]	]	-RRB-
cord-032504-tmohg1mj	20	35	.	.	.
cord-032504-tmohg1mj	21	1	Following	follow	VBG
cord-032504-tmohg1mj	21	2	infection	infection	NN
cord-032504-tmohg1mj	21	3	,	,	,
cord-032504-tmohg1mj	21	4	HIV	HIV	NNP
cord-032504-tmohg1mj	21	5	replicates	replicate	VBZ
cord-032504-tmohg1mj	21	6	unchecked	unchecked	JJ
cord-032504-tmohg1mj	21	7	until	until	IN
cord-032504-tmohg1mj	21	8	an	an	DT
cord-032504-tmohg1mj	21	9	initial	initial	JJ
cord-032504-tmohg1mj	21	10	,	,	,
cord-032504-tmohg1mj	21	11	albeit	albeit	IN
cord-032504-tmohg1mj	21	12	ineffective	ineffective	JJ
cord-032504-tmohg1mj	21	13	,	,	,
cord-032504-tmohg1mj	21	14	host	host	NN
cord-032504-tmohg1mj	21	15	immune	immune	JJ
cord-032504-tmohg1mj	21	16	response	response	NN
cord-032504-tmohg1mj	21	17	develops	develop	VBZ
cord-032504-tmohg1mj	21	18	and	and	CC
cord-032504-tmohg1mj	21	19	the	the	DT
cord-032504-tmohg1mj	21	20	set	set	NN
cord-032504-tmohg1mj	21	21	point	point	NN
cord-032504-tmohg1mj	21	22	is	be	VBZ
cord-032504-tmohg1mj	21	23	established	establish	VBN
cord-032504-tmohg1mj	21	24	[	[	-LRB-
cord-032504-tmohg1mj	21	25	12	12	CD
cord-032504-tmohg1mj	21	26	]	]	-RRB-
cord-032504-tmohg1mj	21	27	[	[	-LRB-
cord-032504-tmohg1mj	21	28	13	13	CD
cord-032504-tmohg1mj	21	29	]	]	-RRB-
cord-032504-tmohg1mj	22	1	[	[	-LRB-
cord-032504-tmohg1mj	22	2	14	14	CD
cord-032504-tmohg1mj	22	3	]	]	-RRB-
cord-032504-tmohg1mj	22	4	.	.	.
cord-032504-tmohg1mj	23	1	When	when	WRB
cord-032504-tmohg1mj	23	2	viewed	view	VBN
cord-032504-tmohg1mj	23	3	through	through	IN
cord-032504-tmohg1mj	23	4	this	this	DT
cord-032504-tmohg1mj	23	5	same	same	JJ
cord-032504-tmohg1mj	23	6	lens	lens	NN
cord-032504-tmohg1mj	23	7	,	,	,
cord-032504-tmohg1mj	23	8	early	early	JJ
cord-032504-tmohg1mj	23	9	host	host	NN
cord-032504-tmohg1mj	23	10	-	-	HYPH
cord-032504-tmohg1mj	23	11	pathogen	pathogen	NN
cord-032504-tmohg1mj	23	12	interactions	interaction	NNS
cord-032504-tmohg1mj	23	13	following	follow	VBG
cord-032504-tmohg1mj	23	14	Mtb	Mtb	NNP
cord-032504-tmohg1mj	23	15	infection	infection	NN
cord-032504-tmohg1mj	23	16	can	can	MD
cord-032504-tmohg1mj	23	17	be	be	VB
cord-032504-tmohg1mj	23	18	thought	think	VBN
cord-032504-tmohg1mj	23	19	of	of	IN
cord-032504-tmohg1mj	23	20	as	as	IN
cord-032504-tmohg1mj	23	21	establishing	establish	VBG
cord-032504-tmohg1mj	23	22	a	a	DT
cord-032504-tmohg1mj	23	23	"	"	``
cord-032504-tmohg1mj	23	24	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	23	25	set	set	NN
cord-032504-tmohg1mj	23	26	point	point	NN
cord-032504-tmohg1mj	23	27	"	"	''
cord-032504-tmohg1mj	23	28	(	(	-LRB-
cord-032504-tmohg1mj	23	29	Fig	fig	NN
cord-032504-tmohg1mj	23	30	.	.	.
cord-032504-tmohg1mj	23	31	1	1	CD
cord-032504-tmohg1mj	23	32	)	)	-RRB-
cord-032504-tmohg1mj	23	33	.	.	.
cord-032504-tmohg1mj	24	1	Unlike	unlike	IN
cord-032504-tmohg1mj	24	2	the	the	DT
cord-032504-tmohg1mj	24	3	set	set	NN
cord-032504-tmohg1mj	24	4	point	point	NN
cord-032504-tmohg1mj	24	5	in	in	IN
cord-032504-tmohg1mj	24	6	HIV	HIV	NNP
cord-032504-tmohg1mj	24	7	,	,	,
cord-032504-tmohg1mj	24	8	which	which	WDT
cord-032504-tmohg1mj	24	9	occurs	occur	VBZ
cord-032504-tmohg1mj	24	10	after	after	IN
cord-032504-tmohg1mj	24	11	an	an	DT
cord-032504-tmohg1mj	24	12	ineffective	ineffective	JJ
cord-032504-tmohg1mj	24	13	adaptive	adaptive	JJ
cord-032504-tmohg1mj	24	14	immune	immune	JJ
cord-032504-tmohg1mj	24	15	response	response	NN
cord-032504-tmohg1mj	24	16	,	,	,
cord-032504-tmohg1mj	24	17	the	the	DT
cord-032504-tmohg1mj	24	18	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	24	19	set	set	NN
cord-032504-tmohg1mj	24	20	point	point	NN
cord-032504-tmohg1mj	24	21	is	be	VBZ
cord-032504-tmohg1mj	24	22	established	establish	VBN
cord-032504-tmohg1mj	24	23	before	before	IN
cord-032504-tmohg1mj	24	24	the	the	DT
cord-032504-tmohg1mj	24	25	onset	onset	NN
cord-032504-tmohg1mj	24	26	of	of	IN
cord-032504-tmohg1mj	24	27	adaptive	adaptive	JJ
cord-032504-tmohg1mj	24	28	immunity	immunity	NN
cord-032504-tmohg1mj	24	29	.	.	.
cord-032504-tmohg1mj	25	1	Although	although	IN
cord-032504-tmohg1mj	25	2	we	-PRON-	PRP
cord-032504-tmohg1mj	25	3	currently	currently	RB
cord-032504-tmohg1mj	25	4	lack	lack	VBP
cord-032504-tmohg1mj	25	5	the	the	DT
cord-032504-tmohg1mj	25	6	tools	tool	NNS
cord-032504-tmohg1mj	25	7	to	to	TO
cord-032504-tmohg1mj	25	8	measure	measure	VB
cord-032504-tmohg1mj	25	9	the	the	DT
cord-032504-tmohg1mj	25	10	mycobaterial	mycobaterial	JJ
cord-032504-tmohg1mj	25	11	set	set	NN
cord-032504-tmohg1mj	25	12	point	point	NN
cord-032504-tmohg1mj	25	13	clinically	clinically	RB
cord-032504-tmohg1mj	25	14	,	,	,
cord-032504-tmohg1mj	25	15	this	this	DT
cord-032504-tmohg1mj	25	16	theoretical	theoretical	JJ
cord-032504-tmohg1mj	25	17	construct	construct	NN
cord-032504-tmohg1mj	25	18	provides	provide	VBZ
cord-032504-tmohg1mj	25	19	a	a	DT
cord-032504-tmohg1mj	25	20	framework	framework	NN
cord-032504-tmohg1mj	25	21	for	for	IN
cord-032504-tmohg1mj	25	22	understanding	understand	VBG
cord-032504-tmohg1mj	25	23	early	early	JJ
cord-032504-tmohg1mj	25	24	immune	immune	JJ
cord-032504-tmohg1mj	25	25	responses	response	NNS
cord-032504-tmohg1mj	25	26	to	to	IN
cord-032504-tmohg1mj	25	27	Mtb	Mtb	NNP
cord-032504-tmohg1mj	25	28	,	,	,
cord-032504-tmohg1mj	25	29	particularly	particularly	RB
cord-032504-tmohg1mj	25	30	those	those	DT
cord-032504-tmohg1mj	25	31	of	of	IN
cord-032504-tmohg1mj	25	32	the	the	DT
cord-032504-tmohg1mj	25	33	alveolar	alveolar	JJ
cord-032504-tmohg1mj	25	34	macrophage	macrophage	NN
cord-032504-tmohg1mj	25	35	.	.	.
cord-032504-tmohg1mj	26	1	While	while	IN
cord-032504-tmohg1mj	26	2	a	a	DT
cord-032504-tmohg1mj	26	3	multitude	multitude	NN
cord-032504-tmohg1mj	26	4	of	of	IN
cord-032504-tmohg1mj	26	5	cell	cell	NN
cord-032504-tmohg1mj	26	6	types	type	NNS
cord-032504-tmohg1mj	26	7	,	,	,
cord-032504-tmohg1mj	26	8	including	include	VBG
cord-032504-tmohg1mj	26	9	recruited	recruit	VBN
cord-032504-tmohg1mj	26	10	interstitial	interstitial	JJ
cord-032504-tmohg1mj	26	11	macrophages	macrophage	NNS
cord-032504-tmohg1mj	26	12	,	,	,
cord-032504-tmohg1mj	26	13	dendritic	dendritic	JJ
cord-032504-tmohg1mj	26	14	cells	cell	NNS
cord-032504-tmohg1mj	26	15	,	,	,
cord-032504-tmohg1mj	26	16	and	and	CC
cord-032504-tmohg1mj	26	17	neutrophils	neutrophil	NNS
cord-032504-tmohg1mj	26	18	,	,	,
cord-032504-tmohg1mj	26	19	are	be	VBP
cord-032504-tmohg1mj	26	20	infected	infect	VBN
cord-032504-tmohg1mj	26	21	prior	prior	RB
cord-032504-tmohg1mj	26	22	to	to	IN
cord-032504-tmohg1mj	26	23	the	the	DT
cord-032504-tmohg1mj	26	24	onset	onset	NN
cord-032504-tmohg1mj	26	25	of	of	IN
cord-032504-tmohg1mj	26	26	adaptive	adaptive	JJ
cord-032504-tmohg1mj	26	27	immunity	immunity	NN
cord-032504-tmohg1mj	26	28	[	[	-LRB-
cord-032504-tmohg1mj	26	29	15	15	CD
cord-032504-tmohg1mj	26	30	]	]	-RRB-
cord-032504-tmohg1mj	26	31	,	,	,
cord-032504-tmohg1mj	26	32	work	work	NN
cord-032504-tmohg1mj	26	33	by	by	IN
cord-032504-tmohg1mj	26	34	Cohen	Cohen	NNP
cord-032504-tmohg1mj	26	35	and	and	CC
cord-032504-tmohg1mj	26	36	others	other	NNS
cord-032504-tmohg1mj	26	37	has	have	VBZ
cord-032504-tmohg1mj	26	38	confirmed	confirm	VBN
cord-032504-tmohg1mj	26	39	the	the	DT
cord-032504-tmohg1mj	26	40	importance	importance	NN
cord-032504-tmohg1mj	26	41	of	of	IN
cord-032504-tmohg1mj	26	42	the	the	DT
cord-032504-tmohg1mj	26	43	alveolar	alveolar	JJ
cord-032504-tmohg1mj	26	44	macrophage	macrophage	NN
cord-032504-tmohg1mj	26	45	to	to	IN
cord-032504-tmohg1mj	26	46	the	the	DT
cord-032504-tmohg1mj	26	47	early	early	JJ
cord-032504-tmohg1mj	26	48	Mtb	Mtb	NNP
cord-032504-tmohg1mj	26	49	response	response	NN
cord-032504-tmohg1mj	26	50	[	[	-LRB-
cord-032504-tmohg1mj	26	51	16	16	CD
cord-032504-tmohg1mj	26	52	]	]	-RRB-
cord-032504-tmohg1mj	26	53	.	.	.
cord-032504-tmohg1mj	27	1	As	as	IN
cord-032504-tmohg1mj	27	2	we	-PRON-	PRP
cord-032504-tmohg1mj	27	3	will	will	MD
cord-032504-tmohg1mj	27	4	emphasize	emphasize	VB
cord-032504-tmohg1mj	27	5	in	in	IN
cord-032504-tmohg1mj	27	6	this	this	DT
cord-032504-tmohg1mj	27	7	review	review	NN
cord-032504-tmohg1mj	27	8	,	,	,
cord-032504-tmohg1mj	27	9	a	a	DT
cord-032504-tmohg1mj	27	10	focus	focus	NN
cord-032504-tmohg1mj	27	11	on	on	IN
cord-032504-tmohg1mj	27	12	this	this	DT
cord-032504-tmohg1mj	27	13	critical	critical	JJ
cord-032504-tmohg1mj	27	14	early	early	JJ
cord-032504-tmohg1mj	27	15	period	period	NN
cord-032504-tmohg1mj	27	16	and	and	CC
cord-032504-tmohg1mj	27	17	the	the	DT
cord-032504-tmohg1mj	27	18	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	27	19	set	set	NN
cord-032504-tmohg1mj	27	20	point	point	NN
cord-032504-tmohg1mj	27	21	are	be	VBP
cord-032504-tmohg1mj	27	22	useful	useful	JJ
cord-032504-tmohg1mj	27	23	in	in	IN
cord-032504-tmohg1mj	27	24	understanding	understand	VBG
cord-032504-tmohg1mj	27	25	the	the	DT
cord-032504-tmohg1mj	27	26	relative	relative	JJ
cord-032504-tmohg1mj	27	27	impacts	impact	NNS
cord-032504-tmohg1mj	27	28	,	,	,
cord-032504-tmohg1mj	27	29	both	both	DT
cord-032504-tmohg1mj	27	30	on	on	IN
cord-032504-tmohg1mj	27	31	a	a	DT
cord-032504-tmohg1mj	27	32	cellular	cellular	JJ
cord-032504-tmohg1mj	27	33	and	and	CC
cord-032504-tmohg1mj	27	34	clinical	clinical	JJ
cord-032504-tmohg1mj	27	35	level	level	NN
cord-032504-tmohg1mj	27	36	,	,	,
cord-032504-tmohg1mj	27	37	of	of	IN
cord-032504-tmohg1mj	27	38	various	various	JJ
cord-032504-tmohg1mj	27	39	host	host	NN
cord-032504-tmohg1mj	27	40	and	and	CC
cord-032504-tmohg1mj	27	41	pathogen	pathogen	NN
cord-032504-tmohg1mj	27	42	impairments	impairment	NNS
cord-032504-tmohg1mj	27	43	that	that	WDT
cord-032504-tmohg1mj	27	44	occur	occur	VBP
cord-032504-tmohg1mj	27	45	in	in	IN
cord-032504-tmohg1mj	27	46	the	the	DT
cord-032504-tmohg1mj	27	47	context	context	NN
cord-032504-tmohg1mj	27	48	of	of	IN
cord-032504-tmohg1mj	27	49	coinfection	coinfection	NN
cord-032504-tmohg1mj	27	50	with	with	IN
cord-032504-tmohg1mj	27	51	Mtb	Mtb	NNP
cord-032504-tmohg1mj	27	52	and	and	CC
cord-032504-tmohg1mj	27	53	HIV	HIV	NNP
cord-032504-tmohg1mj	27	54	.	.	.
cord-032504-tmohg1mj	28	1	The	the	DT
cord-032504-tmohg1mj	28	2	concept	concept	NN
cord-032504-tmohg1mj	28	3	of	of	IN
cord-032504-tmohg1mj	28	4	a	a	DT
cord-032504-tmohg1mj	28	5	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	28	6	set	set	NN
cord-032504-tmohg1mj	28	7	point	point	NN
cord-032504-tmohg1mj	28	8	also	also	RB
cord-032504-tmohg1mj	28	9	provides	provide	VBZ
cord-032504-tmohg1mj	28	10	us	-PRON-	PRP
cord-032504-tmohg1mj	28	11	with	with	IN
cord-032504-tmohg1mj	28	12	an	an	DT
cord-032504-tmohg1mj	28	13	overall	overall	JJ
cord-032504-tmohg1mj	28	14	index	index	NN
cord-032504-tmohg1mj	28	15	of	of	IN
cord-032504-tmohg1mj	28	16	immune	immune	JJ
cord-032504-tmohg1mj	28	17	health	health	NN
cord-032504-tmohg1mj	28	18	in	in	IN
cord-032504-tmohg1mj	28	19	the	the	DT
cord-032504-tmohg1mj	28	20	context	context	NN
cord-032504-tmohg1mj	28	21	of	of	IN
cord-032504-tmohg1mj	28	22	HIV	HIV	NNP
cord-032504-tmohg1mj	28	23	/	/	SYM
cord-032504-tmohg1mj	28	24	Mtb	Mtb	NNP
cord-032504-tmohg1mj	28	25	coinfection	coinfection	NN
cord-032504-tmohg1mj	28	26	and	and	CC
cord-032504-tmohg1mj	28	27	thereby	thereby	RB
cord-032504-tmohg1mj	28	28	offers	offer	VBZ
cord-032504-tmohg1mj	28	29	a	a	DT
cord-032504-tmohg1mj	28	30	useful	useful	JJ
cord-032504-tmohg1mj	28	31	gauge	gauge	NN
cord-032504-tmohg1mj	28	32	of	of	IN
cord-032504-tmohg1mj	28	33	efficacy	efficacy	NN
cord-032504-tmohg1mj	28	34	when	when	WRB
cord-032504-tmohg1mj	28	35	specific	specific	JJ
cord-032504-tmohg1mj	28	36	pathways	pathway	NNS
cord-032504-tmohg1mj	28	37	are	be	VBP
cord-032504-tmohg1mj	28	38	manipulated	manipulate	VBN
cord-032504-tmohg1mj	28	39	for	for	IN
cord-032504-tmohg1mj	28	40	therapeutic	therapeutic	JJ
cord-032504-tmohg1mj	28	41	benefit	benefit	NN
cord-032504-tmohg1mj	28	42	.	.	.
cord-032504-tmohg1mj	29	1	Host	host	NN
cord-032504-tmohg1mj	29	2	immunity	immunity	NN
cord-032504-tmohg1mj	29	3	to	to	IN
cord-032504-tmohg1mj	29	4	Mtb	Mtb	NNP
cord-032504-tmohg1mj	29	5	remains	remain	VBZ
cord-032504-tmohg1mj	29	6	poorly	poorly	RB
cord-032504-tmohg1mj	29	7	understood	understand	VBN
cord-032504-tmohg1mj	29	8	,	,	,
cord-032504-tmohg1mj	29	9	but	but	CC
cord-032504-tmohg1mj	29	10	a	a	DT
cord-032504-tmohg1mj	29	11	focus	focus	NN
cord-032504-tmohg1mj	29	12	on	on	IN
cord-032504-tmohg1mj	29	13	the	the	DT
cord-032504-tmohg1mj	29	14	role	role	NN
cord-032504-tmohg1mj	29	15	of	of	IN
cord-032504-tmohg1mj	29	16	alveolar	alveolar	JJ
cord-032504-tmohg1mj	29	17	macrophages	macrophage	NNS
cord-032504-tmohg1mj	29	18	in	in	IN
cord-032504-tmohg1mj	29	19	establishing	establish	VBG
cord-032504-tmohg1mj	29	20	a	a	DT
cord-032504-tmohg1mj	29	21	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	29	22	set	set	NN
cord-032504-tmohg1mj	29	23	point	point	NN
cord-032504-tmohg1mj	29	24	and	and	CC
cord-032504-tmohg1mj	29	25	on	on	IN
cord-032504-tmohg1mj	29	26	alterations	alteration	NNS
cord-032504-tmohg1mj	29	27	in	in	IN
cord-032504-tmohg1mj	29	28	macrophage	macrophage	NN
cord-032504-tmohg1mj	29	29	control	control	NN
cord-032504-tmohg1mj	29	30	in	in	IN
cord-032504-tmohg1mj	29	31	the	the	DT
cord-032504-tmohg1mj	29	32	context	context	NN
cord-032504-tmohg1mj	29	33	of	of	IN
cord-032504-tmohg1mj	29	34	HIV	HIV	NNP
cord-032504-tmohg1mj	29	35	coinfection	coinfection	NN
cord-032504-tmohg1mj	29	36	has	have	VBZ
cord-032504-tmohg1mj	29	37	the	the	DT
cord-032504-tmohg1mj	29	38	potential	potential	NN
cord-032504-tmohg1mj	29	39	to	to	TO
cord-032504-tmohg1mj	29	40	yield	yield	VB
cord-032504-tmohg1mj	29	41	great	great	JJ
cord-032504-tmohg1mj	29	42	insight	insight	NN
cord-032504-tmohg1mj	29	43	into	into	IN
cord-032504-tmohg1mj	29	44	some	some	DT
cord-032504-tmohg1mj	29	45	of	of	IN
cord-032504-tmohg1mj	29	46	the	the	DT
cord-032504-tmohg1mj	29	47	earliest	early	JJS
cord-032504-tmohg1mj	29	48	immune	immune	JJ
cord-032504-tmohg1mj	29	49	events	event	NNS
cord-032504-tmohg1mj	29	50	in	in	IN
cord-032504-tmohg1mj	29	51	Mtb	Mtb	NNP
cord-032504-tmohg1mj	29	52	infection	infection	NN
cord-032504-tmohg1mj	29	53	.	.	.
cord-032504-tmohg1mj	30	1	Although	although	IN
cord-032504-tmohg1mj	30	2	Mtb	Mtb	NNP
cord-032504-tmohg1mj	30	3	-	-	:
cord-032504-tmohg1mj	30	4	and	and	CC
cord-032504-tmohg1mj	30	5	HIV	HIV	NNP
cord-032504-tmohg1mj	30	6	-	-	HYPH
cord-032504-tmohg1mj	30	7	mediated	mediate	VBN
cord-032504-tmohg1mj	30	8	impairments	impairment	NNS
cord-032504-tmohg1mj	30	9	in	in	IN
cord-032504-tmohg1mj	30	10	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	30	11	innate	innate	JJ
cord-032504-tmohg1mj	30	12	immunity	immunity	NN
cord-032504-tmohg1mj	30	13	and	and	CC
cord-032504-tmohg1mj	30	14	alveolar	alveolar	NN
cord-032504-tmohg1mj	30	15	macrophage	macrophage	NN
cord-032504-tmohg1mj	30	16	function	function	NN
cord-032504-tmohg1mj	30	17	have	have	VBP
cord-032504-tmohg1mj	30	18	been	be	VBN
cord-032504-tmohg1mj	30	19	reviewed	review	VBN
cord-032504-tmohg1mj	30	20	elsewhere	elsewhere	RB
cord-032504-tmohg1mj	30	21	[	[	-LRB-
cord-032504-tmohg1mj	30	22	17	17	CD
cord-032504-tmohg1mj	30	23	,	,	,
cord-032504-tmohg1mj	30	24	18	18	CD
cord-032504-tmohg1mj	30	25	]	]	-RRB-
cord-032504-tmohg1mj	30	26	,	,	,
cord-032504-tmohg1mj	30	27	the	the	DT
cord-032504-tmohg1mj	30	28	impact	impact	NN
cord-032504-tmohg1mj	30	29	of	of	IN
cord-032504-tmohg1mj	30	30	these	these	DT
cord-032504-tmohg1mj	30	31	impairments	impairment	NNS
cord-032504-tmohg1mj	30	32	in	in	IN
cord-032504-tmohg1mj	30	33	the	the	DT
cord-032504-tmohg1mj	30	34	context	context	NN
cord-032504-tmohg1mj	30	35	of	of	IN
cord-032504-tmohg1mj	30	36	coinfection	coinfection	NN
cord-032504-tmohg1mj	30	37	has	have	VBZ
cord-032504-tmohg1mj	30	38	not	not	RB
cord-032504-tmohg1mj	30	39	been	be	VBN
cord-032504-tmohg1mj	30	40	well	well	RB
cord-032504-tmohg1mj	30	41	described	describe	VBN
cord-032504-tmohg1mj	30	42	.	.	.
cord-032504-tmohg1mj	31	1	In	in	IN
cord-032504-tmohg1mj	31	2	this	this	DT
cord-032504-tmohg1mj	31	3	review	review	NN
cord-032504-tmohg1mj	31	4	,	,	,
cord-032504-tmohg1mj	31	5	we	-PRON-	PRP
cord-032504-tmohg1mj	31	6	will	will	MD
cord-032504-tmohg1mj	31	7	explore	explore	VB
cord-032504-tmohg1mj	31	8	how	how	WRB
cord-032504-tmohg1mj	31	9	HIV	HIV	NNP
cord-032504-tmohg1mj	31	10	coinfection	coinfection	NN
cord-032504-tmohg1mj	31	11	makes	make	VBZ
cord-032504-tmohg1mj	31	12	alveolar	alveolar	NN
cord-032504-tmohg1mj	31	13	macrophages	macrophage	NNS
cord-032504-tmohg1mj	31	14	,	,	,
cord-032504-tmohg1mj	31	15	the	the	DT
cord-032504-tmohg1mj	31	16	first	first	JJ
cord-032504-tmohg1mj	31	17	cells	cell	NNS
cord-032504-tmohg1mj	31	18	to	to	TO
cord-032504-tmohg1mj	31	19	encounter	encounter	VB
cord-032504-tmohg1mj	31	20	Mtb	Mtb	NNP
cord-032504-tmohg1mj	31	21	,	,	,
cord-032504-tmohg1mj	31	22	more	more	RBR
cord-032504-tmohg1mj	31	23	permissive	permissive	JJ
cord-032504-tmohg1mj	31	24	of	of	IN
cord-032504-tmohg1mj	31	25	early	early	JJ
cord-032504-tmohg1mj	31	26	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	31	27	growth	growth	NN
cord-032504-tmohg1mj	31	28	and	and	CC
cord-032504-tmohg1mj	31	29	is	be	VBZ
cord-032504-tmohg1mj	31	30	therefore	therefore	RB
cord-032504-tmohg1mj	31	31	likely	likely	JJ
cord-032504-tmohg1mj	31	32	to	to	TO
cord-032504-tmohg1mj	31	33	increase	increase	VB
cord-032504-tmohg1mj	31	34	the	the	DT
cord-032504-tmohg1mj	31	35	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	31	36	burden	burden	NN
cord-032504-tmohg1mj	31	37	at	at	IN
cord-032504-tmohg1mj	31	38	the	the	DT
cord-032504-tmohg1mj	31	39	point	point	NN
cord-032504-tmohg1mj	31	40	at	at	IN
cord-032504-tmohg1mj	31	41	which	which	WDT
cord-032504-tmohg1mj	31	42	adapative	adapative	JJ
cord-032504-tmohg1mj	31	43	immunity	immunity	NN
cord-032504-tmohg1mj	31	44	is	be	VBZ
cord-032504-tmohg1mj	31	45	activated	activate	VBN
cord-032504-tmohg1mj	31	46	and	and	CC
cord-032504-tmohg1mj	31	47	the	the	DT
cord-032504-tmohg1mj	31	48	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	31	49	set	set	NN
cord-032504-tmohg1mj	31	50	point	point	NN
cord-032504-tmohg1mj	31	51	is	be	VBZ
cord-032504-tmohg1mj	31	52	established	establish	VBN
cord-032504-tmohg1mj	31	53	[	[	-LRB-
cord-032504-tmohg1mj	31	54	16	16	CD
cord-032504-tmohg1mj	31	55	]	]	-RRB-
cord-032504-tmohg1mj	31	56	.	.	.
cord-032504-tmohg1mj	32	1	By	by	IN
cord-032504-tmohg1mj	32	2	curtailing	curtail	VBG
cord-032504-tmohg1mj	32	3	early	early	JJ
cord-032504-tmohg1mj	32	4	immune	immune	JJ
cord-032504-tmohg1mj	32	5	control	control	NN
cord-032504-tmohg1mj	32	6	and	and	CC
cord-032504-tmohg1mj	32	7	delaying	delay	VBG
cord-032504-tmohg1mj	32	8	the	the	DT
cord-032504-tmohg1mj	32	9	onset	onset	NN
cord-032504-tmohg1mj	32	10	of	of	IN
cord-032504-tmohg1mj	32	11	adaptive	adaptive	JJ
cord-032504-tmohg1mj	32	12	immunity	immunity	NN
cord-032504-tmohg1mj	32	13	,	,	,
cord-032504-tmohg1mj	32	14	HIV	HIV	NNP
cord-032504-tmohg1mj	32	15	coinfection	coinfection	NN
cord-032504-tmohg1mj	32	16	leads	lead	VBZ
cord-032504-tmohg1mj	32	17	to	to	IN
cord-032504-tmohg1mj	32	18	a	a	DT
cord-032504-tmohg1mj	32	19	higher	high	JJR
cord-032504-tmohg1mj	32	20	mycobacterial	mycobacterial	NN
cord-032504-tmohg1mj	32	21	set	set	NN
cord-032504-tmohg1mj	32	22	point	point	NN
cord-032504-tmohg1mj	32	23	and	and	CC
cord-032504-tmohg1mj	32	24	,	,	,
cord-032504-tmohg1mj	32	25	consequently	consequently	RB
cord-032504-tmohg1mj	32	26	,	,	,
cord-032504-tmohg1mj	32	27	a	a	DT
cord-032504-tmohg1mj	32	28	greater	great	JJR
cord-032504-tmohg1mj	32	29	bacterial	bacterial	JJ
cord-032504-tmohg1mj	32	30	burden	burden	NN
cord-032504-tmohg1mj	32	31	(	(	-LRB-
cord-032504-tmohg1mj	32	32	Fig	Fig	NNP
cord-032504-tmohg1mj	32	33	.	.	.
cord-032504-tmohg1mj	32	34	1	1	CD
cord-032504-tmohg1mj	32	35	)	)	-RRB-
cord-032504-tmohg1mj	32	36	.	.	.
cord-032504-tmohg1mj	33	1	In	in	IN
cord-032504-tmohg1mj	33	2	order	order	NN
cord-032504-tmohg1mj	33	3	to	to	TO
cord-032504-tmohg1mj	33	4	demonstrate	demonstrate	VB
cord-032504-tmohg1mj	33	5	the	the	DT
cord-032504-tmohg1mj	33	6	utility	utility	NN
cord-032504-tmohg1mj	33	7	of	of	IN
cord-032504-tmohg1mj	33	8	the	the	DT
cord-032504-tmohg1mj	33	9	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	33	10	set	set	NNP
cord-032504-tmohg1mj	33	11	point	point	NN
cord-032504-tmohg1mj	33	12	framework	framework	NN
cord-032504-tmohg1mj	33	13	,	,	,
cord-032504-tmohg1mj	33	14	we	-PRON-	PRP
cord-032504-tmohg1mj	33	15	will	will	MD
cord-032504-tmohg1mj	33	16	first	first	RB
cord-032504-tmohg1mj	33	17	review	review	VB
cord-032504-tmohg1mj	33	18	epidemiologic	epidemiologic	JJ
cord-032504-tmohg1mj	33	19	data	datum	NNS
cord-032504-tmohg1mj	33	20	supporting	support	VBG
cord-032504-tmohg1mj	33	21	the	the	DT
cord-032504-tmohg1mj	33	22	importance	importance	NN
cord-032504-tmohg1mj	33	23	of	of	IN
cord-032504-tmohg1mj	33	24	innate	innate	JJ
cord-032504-tmohg1mj	33	25	immunity	immunity	NN
cord-032504-tmohg1mj	33	26	in	in	IN
cord-032504-tmohg1mj	33	27	people	people	NNS
cord-032504-tmohg1mj	33	28	with	with	IN
cord-032504-tmohg1mj	33	29	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	33	30	and	and	CC
cord-032504-tmohg1mj	33	31	HIV	HIV	NNP
cord-032504-tmohg1mj	33	32	coinfection	coinfection	NN
cord-032504-tmohg1mj	33	33	.	.	.
cord-032504-tmohg1mj	34	1	We	-PRON-	PRP
cord-032504-tmohg1mj	34	2	will	will	MD
cord-032504-tmohg1mj	34	3	then	then	RB
cord-032504-tmohg1mj	34	4	discuss	discuss	VB
cord-032504-tmohg1mj	34	5	some	some	DT
cord-032504-tmohg1mj	34	6	of	of	IN
cord-032504-tmohg1mj	34	7	the	the	DT
cord-032504-tmohg1mj	34	8	model	model	NN
cord-032504-tmohg1mj	34	9	systems	system	NNS
cord-032504-tmohg1mj	34	10	that	that	WDT
cord-032504-tmohg1mj	34	11	are	be	VBP
cord-032504-tmohg1mj	34	12	used	use	VBN
cord-032504-tmohg1mj	34	13	to	to	TO
cord-032504-tmohg1mj	34	14	study	study	VB
cord-032504-tmohg1mj	34	15	macrophage	macrophage	NN
cord-032504-tmohg1mj	34	16	responses	response	NNS
cord-032504-tmohg1mj	34	17	to	to	IN
cord-032504-tmohg1mj	34	18	Mtb	Mtb	NNP
cord-032504-tmohg1mj	34	19	and	and	CC
cord-032504-tmohg1mj	34	20	HIV	HIV	NNP
cord-032504-tmohg1mj	34	21	and	and	CC
cord-032504-tmohg1mj	34	22	animal	animal	NN
cord-032504-tmohg1mj	34	23	model	model	NN
cord-032504-tmohg1mj	34	24	findings	finding	NNS
cord-032504-tmohg1mj	34	25	in	in	IN
cord-032504-tmohg1mj	34	26	support	support	NN
cord-032504-tmohg1mj	34	27	of	of	IN
cord-032504-tmohg1mj	34	28	a	a	DT
cord-032504-tmohg1mj	34	29	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	34	30	set	set	NN
cord-032504-tmohg1mj	34	31	point	point	NN
cord-032504-tmohg1mj	34	32	.	.	.
cord-032504-tmohg1mj	35	1	We	-PRON-	PRP
cord-032504-tmohg1mj	35	2	will	will	MD
cord-032504-tmohg1mj	35	3	then	then	RB
cord-032504-tmohg1mj	35	4	highlight	highlight	VB
cord-032504-tmohg1mj	35	5	existing	exist	VBG
cord-032504-tmohg1mj	35	6	data	datum	NNS
cord-032504-tmohg1mj	35	7	on	on	IN
cord-032504-tmohg1mj	35	8	alveolar	alveolar	JJ
cord-032504-tmohg1mj	35	9	macrophage	macrophage	NN
cord-032504-tmohg1mj	35	10	functions	function	NNS
cord-032504-tmohg1mj	35	11	-	-	:
cord-032504-tmohg1mj	35	12	from	from	IN
cord-032504-tmohg1mj	35	13	macrophage	macrophage	NN
cord-032504-tmohg1mj	35	14	phenotype	phenotype	NN
cord-032504-tmohg1mj	35	15	,	,	,
cord-032504-tmohg1mj	35	16	key	key	JJ
cord-032504-tmohg1mj	35	17	cytokines	cytokine	NNS
cord-032504-tmohg1mj	35	18	,	,	,
cord-032504-tmohg1mj	35	19	and	and	CC
cord-032504-tmohg1mj	35	20	oxidative	oxidative	JJ
cord-032504-tmohg1mj	35	21	stress	stress	NN
cord-032504-tmohg1mj	35	22	,	,	,
cord-032504-tmohg1mj	35	23	to	to	TO
cord-032504-tmohg1mj	35	24	pathogen	pathogen	VB
cord-032504-tmohg1mj	35	25	recognition	recognition	NN
cord-032504-tmohg1mj	35	26	and	and	CC
cord-032504-tmohg1mj	35	27	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	35	28	,	,	,
cord-032504-tmohg1mj	35	29	cell	cell	NN
cord-032504-tmohg1mj	35	30	death	death	NN
cord-032504-tmohg1mj	35	31	pathways	pathway	NNS
cord-032504-tmohg1mj	35	32	,	,	,
cord-032504-tmohg1mj	35	33	and	and	CC
cord-032504-tmohg1mj	35	34	activation	activation	NN
cord-032504-tmohg1mj	35	35	Fig	Fig	NNP
cord-032504-tmohg1mj	35	36	.	.	.
cord-032504-tmohg1mj	36	1	1	1	CD
cord-032504-tmohg1mj	36	2	Graphical	graphical	JJ
cord-032504-tmohg1mj	36	3	depiction	depiction	NN
cord-032504-tmohg1mj	36	4	of	of	IN
cord-032504-tmohg1mj	36	5	the	the	DT
cord-032504-tmohg1mj	36	6	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	36	7	set	set	NNP
cord-032504-tmohg1mj	36	8	point	point	NN
cord-032504-tmohg1mj	36	9	as	as	IN
cord-032504-tmohg1mj	36	10	a	a	DT
cord-032504-tmohg1mj	36	11	theoretical	theoretical	JJ
cord-032504-tmohg1mj	36	12	construct	construct	NN
cord-032504-tmohg1mj	36	13	,	,	,
cord-032504-tmohg1mj	36	14	represented	represent	VBN
cord-032504-tmohg1mj	36	15	as	as	IN
cord-032504-tmohg1mj	36	16	the	the	DT
cord-032504-tmohg1mj	36	17	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	36	18	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	36	19	(	(	-LRB-
cord-032504-tmohg1mj	36	20	Mtb	Mtb	NNP
cord-032504-tmohg1mj	36	21	)	)	-RRB-
cord-032504-tmohg1mj	36	22	bacterial	bacterial	JJ
cord-032504-tmohg1mj	36	23	burden	burden	NN
cord-032504-tmohg1mj	36	24	after	after	IN
cord-032504-tmohg1mj	36	25	infection	infection	NN
cord-032504-tmohg1mj	36	26	,	,	,
cord-032504-tmohg1mj	36	27	either	either	CC
cord-032504-tmohg1mj	36	28	alone	alone	RB
cord-032504-tmohg1mj	36	29	or	or	CC
cord-032504-tmohg1mj	36	30	in	in	IN
cord-032504-tmohg1mj	36	31	the	the	DT
cord-032504-tmohg1mj	36	32	context	context	NN
cord-032504-tmohg1mj	36	33	of	of	IN
cord-032504-tmohg1mj	36	34	HIV	HIV	NNP
cord-032504-tmohg1mj	36	35	coinfection	coinfection	NN
cord-032504-tmohg1mj	36	36	.	.	.
cord-032504-tmohg1mj	37	1	After	after	IN
cord-032504-tmohg1mj	37	2	infection	infection	NN
cord-032504-tmohg1mj	37	3	,	,	,
cord-032504-tmohg1mj	37	4	Mtb	Mtb	NNP
cord-032504-tmohg1mj	37	5	bacterial	bacterial	JJ
cord-032504-tmohg1mj	37	6	burden	burden	NN
cord-032504-tmohg1mj	37	7	increases	increase	NNS
cord-032504-tmohg1mj	37	8	until	until	IN
cord-032504-tmohg1mj	37	9	adaptive	adaptive	JJ
cord-032504-tmohg1mj	37	10	immunity	immunity	NN
cord-032504-tmohg1mj	37	11	is	be	VBZ
cord-032504-tmohg1mj	37	12	activated	activate	VBN
cord-032504-tmohg1mj	37	13	,	,	,
cord-032504-tmohg1mj	37	14	thereby	thereby	RB
cord-032504-tmohg1mj	37	15	establishing	establish	VBG
cord-032504-tmohg1mj	37	16	the	the	DT
cord-032504-tmohg1mj	37	17	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	37	18	set	set	NN
cord-032504-tmohg1mj	37	19	point	point	NN
cord-032504-tmohg1mj	37	20	.	.	.
cord-032504-tmohg1mj	38	1	Alveolar	alveolar	NN
cord-032504-tmohg1mj	38	2	macrophages	macrophage	NNS
cord-032504-tmohg1mj	38	3	,	,	,
cord-032504-tmohg1mj	38	4	the	the	DT
cord-032504-tmohg1mj	38	5	first	first	JJ
cord-032504-tmohg1mj	38	6	cells	cell	NNS
cord-032504-tmohg1mj	38	7	to	to	TO
cord-032504-tmohg1mj	38	8	encounter	encounter	VB
cord-032504-tmohg1mj	38	9	Mtb	Mtb	NNP
cord-032504-tmohg1mj	38	10	,	,	,
cord-032504-tmohg1mj	38	11	are	be	VBP
cord-032504-tmohg1mj	38	12	an	an	DT
cord-032504-tmohg1mj	38	13	important	important	JJ
cord-032504-tmohg1mj	38	14	component	component	NN
cord-032504-tmohg1mj	38	15	of	of	IN
cord-032504-tmohg1mj	38	16	the	the	DT
cord-032504-tmohg1mj	38	17	early	early	JJ
cord-032504-tmohg1mj	38	18	innate	innate	JJ
cord-032504-tmohg1mj	38	19	immune	immune	JJ
cord-032504-tmohg1mj	38	20	response	response	NN
cord-032504-tmohg1mj	38	21	to	to	IN
cord-032504-tmohg1mj	38	22	Mtb	Mtb	NNP
cord-032504-tmohg1mj	38	23	.	.	.
cord-032504-tmohg1mj	39	1	As	as	IN
cord-032504-tmohg1mj	39	2	reviewed	review	VBN
cord-032504-tmohg1mj	39	3	in	in	IN
cord-032504-tmohg1mj	39	4	the	the	DT
cord-032504-tmohg1mj	39	5	main	main	JJ
cord-032504-tmohg1mj	39	6	text	text	NN
cord-032504-tmohg1mj	39	7	,	,	,
cord-032504-tmohg1mj	39	8	the	the	DT
cord-032504-tmohg1mj	39	9	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	39	10	burden	burden	NN
cord-032504-tmohg1mj	39	11	at	at	IN
cord-032504-tmohg1mj	39	12	the	the	DT
cord-032504-tmohg1mj	39	13	point	point	NN
cord-032504-tmohg1mj	39	14	of	of	IN
cord-032504-tmohg1mj	39	15	adaptive	adaptive	JJ
cord-032504-tmohg1mj	39	16	immune	immune	JJ
cord-032504-tmohg1mj	39	17	activation	activation	NN
cord-032504-tmohg1mj	39	18	plays	play	VBZ
cord-032504-tmohg1mj	39	19	a	a	DT
cord-032504-tmohg1mj	39	20	important	important	JJ
cord-032504-tmohg1mj	39	21	role	role	NN
cord-032504-tmohg1mj	39	22	in	in	IN
cord-032504-tmohg1mj	39	23	the	the	DT
cord-032504-tmohg1mj	39	24	subsequent	subsequent	JJ
cord-032504-tmohg1mj	39	25	control	control	NN
cord-032504-tmohg1mj	39	26	of	of	IN
cord-032504-tmohg1mj	39	27	infection	infection	NN
cord-032504-tmohg1mj	39	28	and	and	CC
cord-032504-tmohg1mj	39	29	progression	progression	NN
cord-032504-tmohg1mj	39	30	to	to	IN
cord-032504-tmohg1mj	39	31	active	active	JJ
cord-032504-tmohg1mj	39	32	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	39	33	disease	disease	NN
cord-032504-tmohg1mj	39	34	.	.	.
cord-032504-tmohg1mj	40	1	In	in	IN
cord-032504-tmohg1mj	40	2	the	the	DT
cord-032504-tmohg1mj	40	3	case	case	NN
cord-032504-tmohg1mj	40	4	of	of	IN
cord-032504-tmohg1mj	40	5	HIV	HIV	NNP
cord-032504-tmohg1mj	40	6	coinfection	coinfection	NN
cord-032504-tmohg1mj	40	7	,	,	,
cord-032504-tmohg1mj	40	8	impairments	impairment	NNS
cord-032504-tmohg1mj	40	9	in	in	IN
cord-032504-tmohg1mj	40	10	alveolar	alveolar	JJ
cord-032504-tmohg1mj	40	11	macrophage	macrophage	NN
cord-032504-tmohg1mj	40	12	functions	function	NNS
cord-032504-tmohg1mj	40	13	lead	lead	VBP
cord-032504-tmohg1mj	40	14	to	to	IN
cord-032504-tmohg1mj	40	15	poor	poor	JJ
cord-032504-tmohg1mj	40	16	early	early	JJ
cord-032504-tmohg1mj	40	17	immune	immune	JJ
cord-032504-tmohg1mj	40	18	control	control	NN
cord-032504-tmohg1mj	40	19	of	of	IN
cord-032504-tmohg1mj	40	20	Mtb	Mtb	NNP
cord-032504-tmohg1mj	40	21	which	which	WDT
cord-032504-tmohg1mj	40	22	,	,	,
cord-032504-tmohg1mj	40	23	in	in	IN
cord-032504-tmohg1mj	40	24	turn	turn	NN
cord-032504-tmohg1mj	40	25	,	,	,
cord-032504-tmohg1mj	40	26	leads	lead	VBZ
cord-032504-tmohg1mj	40	27	to	to	IN
cord-032504-tmohg1mj	40	28	a	a	DT
cord-032504-tmohg1mj	40	29	higher	high	JJR
cord-032504-tmohg1mj	40	30	mycobacterial	mycobacterial	NN
cord-032504-tmohg1mj	40	31	set	set	NN
cord-032504-tmohg1mj	40	32	point	point	NN
cord-032504-tmohg1mj	40	33	and	and	CC
cord-032504-tmohg1mj	40	34	greater	great	JJR
cord-032504-tmohg1mj	40	35	Mtb	Mtb	NNP
cord-032504-tmohg1mj	40	36	bacterial	bacterial	JJ
cord-032504-tmohg1mj	40	37	burden	burden	NN
cord-032504-tmohg1mj	40	38	at	at	IN
cord-032504-tmohg1mj	40	39	the	the	DT
cord-032504-tmohg1mj	40	40	time	time	NN
cord-032504-tmohg1mj	40	41	when	when	WRB
cord-032504-tmohg1mj	40	42	adaptive	adaptive	JJ
cord-032504-tmohg1mj	40	43	immunity	immunity	NN
cord-032504-tmohg1mj	40	44	is	be	VBZ
cord-032504-tmohg1mj	40	45	activated	activate	VBN
cord-032504-tmohg1mj	40	46	of	of	IN
cord-032504-tmohg1mj	40	47	adaptive	adaptive	JJ
cord-032504-tmohg1mj	40	48	immunity	immunity	NN
cord-032504-tmohg1mj	40	49	-	-	:
cord-032504-tmohg1mj	40	50	that	that	WDT
cord-032504-tmohg1mj	40	51	are	be	VBP
cord-032504-tmohg1mj	40	52	impacted	impact	VBN
cord-032504-tmohg1mj	40	53	by	by	IN
cord-032504-tmohg1mj	40	54	either	either	CC
cord-032504-tmohg1mj	40	55	Mtb	Mtb	NNP
cord-032504-tmohg1mj	40	56	infection	infection	NN
cord-032504-tmohg1mj	40	57	,	,	,
cord-032504-tmohg1mj	40	58	HIV	HIV	NNP
cord-032504-tmohg1mj	40	59	infection	infection	NN
cord-032504-tmohg1mj	40	60	,	,	,
cord-032504-tmohg1mj	40	61	or	or	CC
cord-032504-tmohg1mj	40	62	coinfection	coinfection	NN
cord-032504-tmohg1mj	40	63	.	.	.
cord-032504-tmohg1mj	41	1	The	the	DT
cord-032504-tmohg1mj	41	2	examples	example	NNS
cord-032504-tmohg1mj	41	3	we	-PRON-	PRP
cord-032504-tmohg1mj	41	4	provide	provide	VBP
cord-032504-tmohg1mj	41	5	,	,	,
cord-032504-tmohg1mj	41	6	which	which	WDT
cord-032504-tmohg1mj	41	7	come	come	VBP
cord-032504-tmohg1mj	41	8	from	from	IN
cord-032504-tmohg1mj	41	9	a	a	DT
cord-032504-tmohg1mj	41	10	range	range	NN
cord-032504-tmohg1mj	41	11	of	of	IN
cord-032504-tmohg1mj	41	12	cell	cell	NN
cord-032504-tmohg1mj	41	13	types	type	NNS
cord-032504-tmohg1mj	41	14	and	and	CC
cord-032504-tmohg1mj	41	15	organ	organ	NN
cord-032504-tmohg1mj	41	16	systems	system	NNS
cord-032504-tmohg1mj	41	17	,	,	,
cord-032504-tmohg1mj	41	18	including	include	VBG
cord-032504-tmohg1mj	41	19	primary	primary	JJ
cord-032504-tmohg1mj	41	20	alveolar	alveolar	NN
cord-032504-tmohg1mj	41	21	macrophages	macrophage	NNS
cord-032504-tmohg1mj	41	22	,	,	,
cord-032504-tmohg1mj	41	23	monocyte	monocyte	NNP
cord-032504-tmohg1mj	41	24	-	-	HYPH
cord-032504-tmohg1mj	41	25	derived	derive	VBN
cord-032504-tmohg1mj	41	26	macrophages	macrophage	NNS
cord-032504-tmohg1mj	41	27	,	,	,
cord-032504-tmohg1mj	41	28	and	and	CC
cord-032504-tmohg1mj	41	29	cell	cell	NN
cord-032504-tmohg1mj	41	30	lines	line	NNS
cord-032504-tmohg1mj	41	31	,	,	,
cord-032504-tmohg1mj	41	32	are	be	VBP
cord-032504-tmohg1mj	41	33	not	not	RB
cord-032504-tmohg1mj	41	34	meant	mean	VBN
cord-032504-tmohg1mj	41	35	to	to	TO
cord-032504-tmohg1mj	41	36	be	be	VB
cord-032504-tmohg1mj	41	37	exhaustive	exhaustive	JJ
cord-032504-tmohg1mj	41	38	or	or	CC
cord-032504-tmohg1mj	41	39	comprehensive	comprehensive	JJ
cord-032504-tmohg1mj	41	40	.	.	.
cord-032504-tmohg1mj	42	1	Rather	rather	RB
cord-032504-tmohg1mj	42	2	,	,	,
cord-032504-tmohg1mj	42	3	our	-PRON-	PRP$
cord-032504-tmohg1mj	42	4	goal	goal	NN
cord-032504-tmohg1mj	42	5	is	be	VBZ
cord-032504-tmohg1mj	42	6	to	to	TO
cord-032504-tmohg1mj	42	7	provoke	provoke	VB
cord-032504-tmohg1mj	42	8	further	further	JJ
cord-032504-tmohg1mj	42	9	inquiry	inquiry	NN
cord-032504-tmohg1mj	42	10	and	and	CC
cord-032504-tmohg1mj	42	11	investigation	investigation	NN
cord-032504-tmohg1mj	42	12	into	into	IN
cord-032504-tmohg1mj	42	13	this	this	DT
cord-032504-tmohg1mj	42	14	critical	critical	JJ
cord-032504-tmohg1mj	42	15	area	area	NN
cord-032504-tmohg1mj	42	16	by	by	IN
cord-032504-tmohg1mj	42	17	offering	offer	VBG
cord-032504-tmohg1mj	42	18	a	a	DT
cord-032504-tmohg1mj	42	19	framework	framework	NN
cord-032504-tmohg1mj	42	20	by	by	IN
cord-032504-tmohg1mj	42	21	which	which	WDT
cord-032504-tmohg1mj	42	22	to	to	TO
cord-032504-tmohg1mj	42	23	contextualize	contextualize	VB
cord-032504-tmohg1mj	42	24	studies	study	NNS
cord-032504-tmohg1mj	42	25	in	in	IN
cord-032504-tmohg1mj	42	26	the	the	DT
cord-032504-tmohg1mj	42	27	field	field	NN
cord-032504-tmohg1mj	42	28	.	.	.
cord-032504-tmohg1mj	43	1	We	-PRON-	PRP
cord-032504-tmohg1mj	43	2	will	will	MD
cord-032504-tmohg1mj	43	3	close	close	VB
cord-032504-tmohg1mj	43	4	the	the	DT
cord-032504-tmohg1mj	43	5	review	review	NN
cord-032504-tmohg1mj	43	6	by	by	IN
cord-032504-tmohg1mj	43	7	highlighting	highlight	VBG
cord-032504-tmohg1mj	43	8	several	several	JJ
cord-032504-tmohg1mj	43	9	promising	promising	JJ
cord-032504-tmohg1mj	43	10	avenues	avenue	NNS
cord-032504-tmohg1mj	43	11	for	for	IN
cord-032504-tmohg1mj	43	12	studying	study	VBG
cord-032504-tmohg1mj	43	13	the	the	DT
cord-032504-tmohg1mj	43	14	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	43	15	set	set	VBN
cord-032504-tmohg1mj	43	16	point	point	NN
cord-032504-tmohg1mj	43	17	in	in	IN
cord-032504-tmohg1mj	43	18	humans	human	NNS
cord-032504-tmohg1mj	43	19	,	,	,
cord-032504-tmohg1mj	43	20	in	in	IN
cord-032504-tmohg1mj	43	21	order	order	NN
cord-032504-tmohg1mj	43	22	to	to	TO
cord-032504-tmohg1mj	43	23	underscore	underscore	VB
cord-032504-tmohg1mj	43	24	the	the	DT
cord-032504-tmohg1mj	43	25	potential	potential	JJ
cord-032504-tmohg1mj	43	26	benefit	benefit	NN
cord-032504-tmohg1mj	43	27	of	of	IN
cord-032504-tmohg1mj	43	28	this	this	DT
cord-032504-tmohg1mj	43	29	concept	concept	NN
cord-032504-tmohg1mj	43	30	as	as	IN
cord-032504-tmohg1mj	43	31	a	a	DT
cord-032504-tmohg1mj	43	32	framework	framework	NN
cord-032504-tmohg1mj	43	33	for	for	IN
cord-032504-tmohg1mj	43	34	clinically	clinically	RB
cord-032504-tmohg1mj	43	35	relevant	relevant	JJ
cord-032504-tmohg1mj	43	36	research	research	NN
cord-032504-tmohg1mj	43	37	.	.	.
cord-032504-tmohg1mj	44	1	From	from	IN
cord-032504-tmohg1mj	44	2	the	the	DT
cord-032504-tmohg1mj	44	3	earliest	early	JJS
cord-032504-tmohg1mj	44	4	days	day	NNS
cord-032504-tmohg1mj	44	5	of	of	IN
cord-032504-tmohg1mj	44	6	the	the	DT
cord-032504-tmohg1mj	44	7	HIV	HIV	NNP
cord-032504-tmohg1mj	44	8	epidemic	epidemic	NN
cord-032504-tmohg1mj	44	9	it	-PRON-	PRP
cord-032504-tmohg1mj	44	10	has	have	VBZ
cord-032504-tmohg1mj	44	11	been	be	VBN
cord-032504-tmohg1mj	44	12	clear	clear	JJ
cord-032504-tmohg1mj	44	13	that	that	IN
cord-032504-tmohg1mj	44	14	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	44	15	outcomes	outcome	NNS
cord-032504-tmohg1mj	44	16	were	be	VBD
cord-032504-tmohg1mj	44	17	markedly	markedly	RB
cord-032504-tmohg1mj	44	18	worse	bad	JJR
cord-032504-tmohg1mj	44	19	in	in	IN
cord-032504-tmohg1mj	44	20	people	people	NNS
cord-032504-tmohg1mj	44	21	with	with	IN
cord-032504-tmohg1mj	44	22	HIV	HIV	NNP
cord-032504-tmohg1mj	44	23	.	.	.
cord-032504-tmohg1mj	45	1	In	in	IN
cord-032504-tmohg1mj	45	2	a	a	DT
cord-032504-tmohg1mj	45	3	series	series	NN
cord-032504-tmohg1mj	45	4	of	of	IN
cord-032504-tmohg1mj	45	5	nosocomial	nosocomial	JJ
cord-032504-tmohg1mj	45	6	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	45	7	outbreaks	outbreak	NNS
cord-032504-tmohg1mj	45	8	among	among	IN
cord-032504-tmohg1mj	45	9	people	people	NNS
cord-032504-tmohg1mj	45	10	with	with	IN
cord-032504-tmohg1mj	45	11	HIV	HIV	NNP
cord-032504-tmohg1mj	45	12	in	in	IN
cord-032504-tmohg1mj	45	13	the	the	DT
cord-032504-tmohg1mj	45	14	early	early	JJ
cord-032504-tmohg1mj	45	15	1990s	1990	NNS
cord-032504-tmohg1mj	45	16	,	,	,
cord-032504-tmohg1mj	45	17	the	the	DT
cord-032504-tmohg1mj	45	18	overwhelming	overwhelming	JJ
cord-032504-tmohg1mj	45	19	majority	majority	NN
cord-032504-tmohg1mj	45	20	of	of	IN
cord-032504-tmohg1mj	45	21	patients	patient	NNS
cord-032504-tmohg1mj	45	22	died	die	VBD
cord-032504-tmohg1mj	45	23	,	,	,
cord-032504-tmohg1mj	45	24	often	often	RB
cord-032504-tmohg1mj	45	25	within	within	IN
cord-032504-tmohg1mj	45	26	a	a	DT
cord-032504-tmohg1mj	45	27	month	month	NN
cord-032504-tmohg1mj	45	28	or	or	CC
cord-032504-tmohg1mj	45	29	two	two	CD
cord-032504-tmohg1mj	45	30	of	of	IN
cord-032504-tmohg1mj	45	31	their	-PRON-	PRP$
cord-032504-tmohg1mj	45	32	diagnosis	diagnosis	NN
cord-032504-tmohg1mj	45	33	[	[	-LRB-
cord-032504-tmohg1mj	45	34	19	19	CD
cord-032504-tmohg1mj	45	35	]	]	-RRB-
cord-032504-tmohg1mj	45	36	[	[	-LRB-
cord-032504-tmohg1mj	45	37	20	20	CD
cord-032504-tmohg1mj	45	38	]	]	-RRB-
cord-032504-tmohg1mj	45	39	[	[	-LRB-
cord-032504-tmohg1mj	45	40	21	21	CD
cord-032504-tmohg1mj	45	41	]	]	-RRB-
cord-032504-tmohg1mj	45	42	.	.	.
cord-032504-tmohg1mj	46	1	These	these	DT
cord-032504-tmohg1mj	46	2	individuals	individual	NNS
cord-032504-tmohg1mj	46	3	had	have	VBD
cord-032504-tmohg1mj	46	4	very	very	RB
cord-032504-tmohg1mj	46	5	advanced	advanced	JJ
cord-032504-tmohg1mj	46	6	HIV	HIV	NNP
cord-032504-tmohg1mj	46	7	,	,	,
cord-032504-tmohg1mj	46	8	which	which	WDT
cord-032504-tmohg1mj	46	9	undoubtedly	undoubtedly	RB
cord-032504-tmohg1mj	46	10	contributed	contribute	VBD
cord-032504-tmohg1mj	46	11	to	to	IN
cord-032504-tmohg1mj	46	12	their	-PRON-	PRP$
cord-032504-tmohg1mj	46	13	high	high	JJ
cord-032504-tmohg1mj	46	14	mortality	mortality	NN
cord-032504-tmohg1mj	46	15	rates	rate	NNS
cord-032504-tmohg1mj	46	16	[	[	-LRB-
cord-032504-tmohg1mj	46	17	21	21	CD
cord-032504-tmohg1mj	46	18	]	]	-RRB-
cord-032504-tmohg1mj	46	19	.	.	.
cord-032504-tmohg1mj	47	1	However	however	RB
cord-032504-tmohg1mj	47	2	,	,	,
cord-032504-tmohg1mj	47	3	their	-PRON-	PRP$
cord-032504-tmohg1mj	47	4	rapid	rapid	JJ
cord-032504-tmohg1mj	47	5	progression	progression	NN
cord-032504-tmohg1mj	47	6	from	from	IN
cord-032504-tmohg1mj	47	7	exposure	exposure	NN
cord-032504-tmohg1mj	47	8	to	to	IN
cord-032504-tmohg1mj	47	9	active	active	JJ
cord-032504-tmohg1mj	47	10	disease	disease	NN
cord-032504-tmohg1mj	47	11	,	,	,
cord-032504-tmohg1mj	47	12	in	in	IN
cord-032504-tmohg1mj	47	13	a	a	DT
cord-032504-tmohg1mj	47	14	time	time	NN
cord-032504-tmohg1mj	47	15	frame	frame	NN
cord-032504-tmohg1mj	47	16	prior	prior	RB
cord-032504-tmohg1mj	47	17	to	to	IN
cord-032504-tmohg1mj	47	18	the	the	DT
cord-032504-tmohg1mj	47	19	expected	expect	VBN
cord-032504-tmohg1mj	47	20	onset	onset	NN
cord-032504-tmohg1mj	47	21	of	of	IN
cord-032504-tmohg1mj	47	22	adaptive	adaptive	JJ
cord-032504-tmohg1mj	47	23	immunity	immunity	NN
cord-032504-tmohg1mj	47	24	,	,	,
cord-032504-tmohg1mj	47	25	suggests	suggest	VBZ
cord-032504-tmohg1mj	47	26	that	that	IN
cord-032504-tmohg1mj	47	27	impaired	impair	VBN
cord-032504-tmohg1mj	47	28	innate	innate	JJ
cord-032504-tmohg1mj	47	29	immunity	immunity	NN
cord-032504-tmohg1mj	47	30	was	be	VBD
cord-032504-tmohg1mj	47	31	likely	likely	RB
cord-032504-tmohg1mj	47	32	a	a	DT
cord-032504-tmohg1mj	47	33	contributing	contribute	VBG
cord-032504-tmohg1mj	47	34	factor	factor	NN
cord-032504-tmohg1mj	47	35	.	.	.
cord-032504-tmohg1mj	48	1	Similarly	similarly	RB
cord-032504-tmohg1mj	48	2	,	,	,
cord-032504-tmohg1mj	48	3	in	in	IN
cord-032504-tmohg1mj	48	4	a	a	DT
cord-032504-tmohg1mj	48	5	study	study	NN
cord-032504-tmohg1mj	48	6	of	of	IN
cord-032504-tmohg1mj	48	7	South	south	JJ
cord-032504-tmohg1mj	48	8	African	african	JJ
cord-032504-tmohg1mj	48	9	gold	gold	NN
cord-032504-tmohg1mj	48	10	miners	miner	NNS
cord-032504-tmohg1mj	48	11	newly	newly	RB
cord-032504-tmohg1mj	48	12	infected	infect	VBN
cord-032504-tmohg1mj	48	13	with	with	IN
cord-032504-tmohg1mj	48	14	HIV	HIV	NNP
cord-032504-tmohg1mj	48	15	,	,	,
cord-032504-tmohg1mj	48	16	the	the	DT
cord-032504-tmohg1mj	48	17	risk	risk	NN
cord-032504-tmohg1mj	48	18	of	of	IN
cord-032504-tmohg1mj	48	19	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	48	20	disease	disease	NN
cord-032504-tmohg1mj	48	21	was	be	VBD
cord-032504-tmohg1mj	48	22	found	find	VBN
cord-032504-tmohg1mj	48	23	to	to	TO
cord-032504-tmohg1mj	48	24	increase	increase	VB
cord-032504-tmohg1mj	48	25	very	very	RB
cord-032504-tmohg1mj	48	26	early	early	RB
cord-032504-tmohg1mj	48	27	in	in	IN
cord-032504-tmohg1mj	48	28	the	the	DT
cord-032504-tmohg1mj	48	29	course	course	NN
cord-032504-tmohg1mj	48	30	of	of	IN
cord-032504-tmohg1mj	48	31	HIV	HIV	NNP
cord-032504-tmohg1mj	48	32	infection	infection	NN
cord-032504-tmohg1mj	48	33	,	,	,
cord-032504-tmohg1mj	48	34	when	when	WRB
cord-032504-tmohg1mj	48	35	CD4	CD4	NNP
cord-032504-tmohg1mj	48	36	counts	count	VBZ
cord-032504-tmohg1mj	48	37	would	would	MD
cord-032504-tmohg1mj	48	38	still	still	RB
cord-032504-tmohg1mj	48	39	be	be	VB
cord-032504-tmohg1mj	48	40	in	in	IN
cord-032504-tmohg1mj	48	41	a	a	DT
cord-032504-tmohg1mj	48	42	normal	normal	JJ
cord-032504-tmohg1mj	48	43	range	range	NN
cord-032504-tmohg1mj	48	44	[	[	-LRB-
cord-032504-tmohg1mj	48	45	22	22	CD
cord-032504-tmohg1mj	48	46	]	]	-RRB-
cord-032504-tmohg1mj	48	47	.	.	.
cord-032504-tmohg1mj	49	1	Another	another	DT
cord-032504-tmohg1mj	49	2	study	study	NN
cord-032504-tmohg1mj	49	3	from	from	IN
cord-032504-tmohg1mj	49	4	South	South	NNP
cord-032504-tmohg1mj	49	5	Africa	Africa	NNP
cord-032504-tmohg1mj	49	6	found	find	VBD
cord-032504-tmohg1mj	49	7	that	that	IN
cord-032504-tmohg1mj	49	8	people	people	NNS
cord-032504-tmohg1mj	49	9	with	with	IN
cord-032504-tmohg1mj	49	10	HIV	HIV	NNP
cord-032504-tmohg1mj	49	11	on	on	IN
cord-032504-tmohg1mj	49	12	antiretroviral	antiretroviral	JJ
cord-032504-tmohg1mj	49	13	therapy	therapy	NN
cord-032504-tmohg1mj	49	14	(	(	-LRB-
cord-032504-tmohg1mj	49	15	ART	art	NN
cord-032504-tmohg1mj	49	16	)	)	-RRB-
cord-032504-tmohg1mj	49	17	with	with	IN
cord-032504-tmohg1mj	49	18	normal	normal	JJ
cord-032504-tmohg1mj	49	19	CD4	CD4	NNP
cord-032504-tmohg1mj	49	20	counts	count	NNS
cord-032504-tmohg1mj	49	21	had	have	VBD
cord-032504-tmohg1mj	49	22	four	four	CD
cord-032504-tmohg1mj	49	23	times	time	NNS
cord-032504-tmohg1mj	49	24	the	the	DT
cord-032504-tmohg1mj	49	25	risk	risk	NN
cord-032504-tmohg1mj	49	26	of	of	IN
cord-032504-tmohg1mj	49	27	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	49	28	than	than	IN
cord-032504-tmohg1mj	49	29	people	people	NNS
cord-032504-tmohg1mj	49	30	without	without	IN
cord-032504-tmohg1mj	49	31	HIV	HIV	NNP
cord-032504-tmohg1mj	49	32	[	[	-LRB-
cord-032504-tmohg1mj	49	33	23	23	CD
cord-032504-tmohg1mj	49	34	]	]	-RRB-
cord-032504-tmohg1mj	49	35	.	.	.
cord-032504-tmohg1mj	50	1	Likewise	likewise	RB
cord-032504-tmohg1mj	50	2	,	,	,
cord-032504-tmohg1mj	50	3	in	in	IN
cord-032504-tmohg1mj	50	4	Italy	Italy	NNP
cord-032504-tmohg1mj	50	5	,	,	,
cord-032504-tmohg1mj	50	6	a	a	DT
cord-032504-tmohg1mj	50	7	setting	setting	NN
cord-032504-tmohg1mj	50	8	with	with	IN
cord-032504-tmohg1mj	50	9	a	a	DT
cord-032504-tmohg1mj	50	10	low	low	JJ
cord-032504-tmohg1mj	50	11	burden	burden	NN
cord-032504-tmohg1mj	50	12	of	of	IN
cord-032504-tmohg1mj	50	13	both	both	CC
cord-032504-tmohg1mj	50	14	HIV	HIV	NNP
cord-032504-tmohg1mj	50	15	and	and	CC
cord-032504-tmohg1mj	50	16	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	50	17	,	,	,
cord-032504-tmohg1mj	50	18	nearly	nearly	RB
cord-032504-tmohg1mj	50	19	a	a	DT
cord-032504-tmohg1mj	50	20	third	third	NN
cord-032504-tmohg1mj	50	21	of	of	IN
cord-032504-tmohg1mj	50	22	patients	patient	NNS
cord-032504-tmohg1mj	50	23	diagnosed	diagnose	VBN
cord-032504-tmohg1mj	50	24	with	with	IN
cord-032504-tmohg1mj	50	25	HIV	HIV	NNP
cord-032504-tmohg1mj	50	26	-	-	HYPH
cord-032504-tmohg1mj	50	27	associated	associate	VBN
cord-032504-tmohg1mj	50	28	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	50	29	in	in	IN
cord-032504-tmohg1mj	50	30	one	one	CD
cord-032504-tmohg1mj	50	31	study	study	NN
cord-032504-tmohg1mj	50	32	had	have	VBD
cord-032504-tmohg1mj	50	33	been	be	VBN
cord-032504-tmohg1mj	50	34	receiving	receive	VBG
cord-032504-tmohg1mj	50	35	ART	art	NN
cord-032504-tmohg1mj	50	36	for	for	IN
cord-032504-tmohg1mj	50	37	a	a	DT
cord-032504-tmohg1mj	50	38	median	median	NN
cord-032504-tmohg1mj	50	39	of	of	IN
cord-032504-tmohg1mj	50	40	27	27	CD
cord-032504-tmohg1mj	50	41	months	month	NNS
cord-032504-tmohg1mj	50	42	,	,	,
cord-032504-tmohg1mj	50	43	at	at	IN
cord-032504-tmohg1mj	50	44	which	which	WDT
cord-032504-tmohg1mj	50	45	point	point	NN
cord-032504-tmohg1mj	50	46	CD4	CD4	NNP
cord-032504-tmohg1mj	50	47	counts	count	VBZ
cord-032504-tmohg1mj	50	48	would	would	MD
cord-032504-tmohg1mj	50	49	typically	typically	RB
cord-032504-tmohg1mj	50	50	have	have	VB
cord-032504-tmohg1mj	50	51	reached	reach	VBN
cord-032504-tmohg1mj	50	52	a	a	DT
cord-032504-tmohg1mj	50	53	normal	normal	JJ
cord-032504-tmohg1mj	50	54	range	range	NN
cord-032504-tmohg1mj	50	55	[	[	-LRB-
cord-032504-tmohg1mj	50	56	24	24	CD
cord-032504-tmohg1mj	50	57	]	]	-RRB-
cord-032504-tmohg1mj	50	58	.	.	.
cord-032504-tmohg1mj	51	1	Taken	take	VBN
cord-032504-tmohg1mj	51	2	together	together	RB
cord-032504-tmohg1mj	51	3	,	,	,
cord-032504-tmohg1mj	51	4	these	these	DT
cord-032504-tmohg1mj	51	5	data	datum	NNS
cord-032504-tmohg1mj	51	6	offer	offer	VBP
cord-032504-tmohg1mj	51	7	epidemiologic	epidemiologic	JJ
cord-032504-tmohg1mj	51	8	evidence	evidence	NN
cord-032504-tmohg1mj	51	9	that	that	IN
cord-032504-tmohg1mj	51	10	defects	defect	NNS
cord-032504-tmohg1mj	51	11	in	in	IN
cord-032504-tmohg1mj	51	12	both	both	DT
cord-032504-tmohg1mj	51	13	innate	innate	JJ
cord-032504-tmohg1mj	51	14	and	and	CC
cord-032504-tmohg1mj	51	15	adaptive	adaptive	JJ
cord-032504-tmohg1mj	51	16	immunity	immunity	NN
cord-032504-tmohg1mj	51	17	are	be	VBP
cord-032504-tmohg1mj	51	18	likely	likely	JJ
cord-032504-tmohg1mj	51	19	to	to	TO
cord-032504-tmohg1mj	51	20	contribute	contribute	VB
cord-032504-tmohg1mj	51	21	to	to	IN
cord-032504-tmohg1mj	51	22	the	the	DT
cord-032504-tmohg1mj	51	23	greater	great	JJR
cord-032504-tmohg1mj	51	24	risk	risk	NN
cord-032504-tmohg1mj	51	25	of	of	IN
cord-032504-tmohg1mj	51	26	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	51	27	in	in	IN
cord-032504-tmohg1mj	51	28	people	people	NNS
cord-032504-tmohg1mj	51	29	with	with	IN
cord-032504-tmohg1mj	51	30	HIV	HIV	NNP
cord-032504-tmohg1mj	51	31	.	.	.
cord-032504-tmohg1mj	52	1	While	while	IN
cord-032504-tmohg1mj	52	2	these	these	DT
cord-032504-tmohg1mj	52	3	clinical	clinical	JJ
cord-032504-tmohg1mj	52	4	observations	observation	NNS
cord-032504-tmohg1mj	52	5	can	can	MD
cord-032504-tmohg1mj	52	6	not	not	RB
cord-032504-tmohg1mj	52	7	establish	establish	VB
cord-032504-tmohg1mj	52	8	mechanism	mechanism	NN
cord-032504-tmohg1mj	52	9	or	or	CC
cord-032504-tmohg1mj	52	10	causality	causality	NN
cord-032504-tmohg1mj	52	11	,	,	,
cord-032504-tmohg1mj	52	12	they	-PRON-	PRP
cord-032504-tmohg1mj	52	13	do	do	VBP
cord-032504-tmohg1mj	52	14	provide	provide	VB
cord-032504-tmohg1mj	52	15	a	a	DT
cord-032504-tmohg1mj	52	16	rationale	rationale	NN
cord-032504-tmohg1mj	52	17	for	for	IN
cord-032504-tmohg1mj	52	18	pursuing	pursue	VBG
cord-032504-tmohg1mj	52	19	further	further	JJ
cord-032504-tmohg1mj	52	20	basic	basic	JJ
cord-032504-tmohg1mj	52	21	science	science	NN
cord-032504-tmohg1mj	52	22	and	and	CC
cord-032504-tmohg1mj	52	23	translational	translational	JJ
cord-032504-tmohg1mj	52	24	studies	study	NNS
cord-032504-tmohg1mj	52	25	to	to	TO
cord-032504-tmohg1mj	52	26	better	better	RB
cord-032504-tmohg1mj	52	27	understand	understand	VB
cord-032504-tmohg1mj	52	28	the	the	DT
cord-032504-tmohg1mj	52	29	role	role	NN
cord-032504-tmohg1mj	52	30	of	of	IN
cord-032504-tmohg1mj	52	31	innate	innate	JJ
cord-032504-tmohg1mj	52	32	immunity	immunity	NN
cord-032504-tmohg1mj	52	33	in	in	IN
cord-032504-tmohg1mj	52	34	controlling	control	VBG
cord-032504-tmohg1mj	52	35	Mtb	Mtb	NNP
cord-032504-tmohg1mj	52	36	infection	infection	NN
cord-032504-tmohg1mj	52	37	.	.	.
cord-032504-tmohg1mj	53	1	Over	over	IN
cord-032504-tmohg1mj	53	2	the	the	DT
cord-032504-tmohg1mj	53	3	last	last	JJ
cord-032504-tmohg1mj	53	4	century	century	NN
cord-032504-tmohg1mj	53	5	,	,	,
cord-032504-tmohg1mj	53	6	scientists	scientist	NNS
cord-032504-tmohg1mj	53	7	from	from	IN
cord-032504-tmohg1mj	53	8	successive	successive	JJ
cord-032504-tmohg1mj	53	9	eras	era	NNS
cord-032504-tmohg1mj	53	10	have	have	VBP
cord-032504-tmohg1mj	53	11	made	make	VBN
cord-032504-tmohg1mj	53	12	remarkable	remarkable	JJ
cord-032504-tmohg1mj	53	13	discoveries	discovery	NNS
cord-032504-tmohg1mj	53	14	by	by	IN
cord-032504-tmohg1mj	53	15	bringing	bring	VBG
cord-032504-tmohg1mj	53	16	the	the	DT
cord-032504-tmohg1mj	53	17	newest	new	JJS
cord-032504-tmohg1mj	53	18	available	available	JJ
cord-032504-tmohg1mj	53	19	techniques	technique	NNS
cord-032504-tmohg1mj	53	20	to	to	TO
cord-032504-tmohg1mj	53	21	bear	bear	VB
cord-032504-tmohg1mj	53	22	on	on	IN
cord-032504-tmohg1mj	53	23	their	-PRON-	PRP$
cord-032504-tmohg1mj	53	24	investigations	investigation	NNS
cord-032504-tmohg1mj	53	25	of	of	IN
cord-032504-tmohg1mj	53	26	Mtb	Mtb	NNP
cord-032504-tmohg1mj	53	27	,	,	,
cord-032504-tmohg1mj	53	28	with	with	IN
cord-032504-tmohg1mj	53	29	various	various	JJ
cord-032504-tmohg1mj	53	30	model	model	NN
cord-032504-tmohg1mj	53	31	systems	system	NNS
cord-032504-tmohg1mj	53	32	employed	employ	VBN
cord-032504-tmohg1mj	53	33	over	over	IN
cord-032504-tmohg1mj	53	34	time	time	NN
cord-032504-tmohg1mj	53	35	.	.	.
cord-032504-tmohg1mj	54	1	While	while	IN
cord-032504-tmohg1mj	54	2	each	each	DT
cord-032504-tmohg1mj	54	3	system	system	NN
cord-032504-tmohg1mj	54	4	has	have	VBZ
cord-032504-tmohg1mj	54	5	distinct	distinct	JJ
cord-032504-tmohg1mj	54	6	advantages	advantage	NNS
cord-032504-tmohg1mj	54	7	and	and	CC
cord-032504-tmohg1mj	54	8	disadvantages	disadvantage	NNS
cord-032504-tmohg1mj	54	9	in	in	IN
cord-032504-tmohg1mj	54	10	addressing	address	VBG
cord-032504-tmohg1mj	54	11	particular	particular	JJ
cord-032504-tmohg1mj	54	12	questions	question	NNS
cord-032504-tmohg1mj	54	13	,	,	,
cord-032504-tmohg1mj	54	14	the	the	DT
cord-032504-tmohg1mj	54	15	sheer	sheer	JJ
cord-032504-tmohg1mj	54	16	volume	volume	NN
cord-032504-tmohg1mj	54	17	of	of	IN
cord-032504-tmohg1mj	54	18	data	datum	NNS
cord-032504-tmohg1mj	54	19	derived	derive	VBN
cord-032504-tmohg1mj	54	20	from	from	IN
cord-032504-tmohg1mj	54	21	the	the	DT
cord-032504-tmohg1mj	54	22	many	many	JJ
cord-032504-tmohg1mj	54	23	available	available	JJ
cord-032504-tmohg1mj	54	24	systems	system	NNS
cord-032504-tmohg1mj	54	25	can	can	MD
cord-032504-tmohg1mj	54	26	make	make	VB
cord-032504-tmohg1mj	54	27	it	-PRON-	PRP
cord-032504-tmohg1mj	54	28	hard	hard	JJ
cord-032504-tmohg1mj	54	29	to	to	TO
cord-032504-tmohg1mj	54	30	develop	develop	VB
cord-032504-tmohg1mj	54	31	a	a	DT
cord-032504-tmohg1mj	54	32	coherent	coherent	JJ
cord-032504-tmohg1mj	54	33	narrative	narrative	NN
cord-032504-tmohg1mj	54	34	regarding	regard	VBG
cord-032504-tmohg1mj	54	35	Mtb	Mtb	NNP
cord-032504-tmohg1mj	54	36	infection	infection	NN
cord-032504-tmohg1mj	54	37	in	in	IN
cord-032504-tmohg1mj	54	38	humans	human	NNS
cord-032504-tmohg1mj	54	39	.	.	.
cord-032504-tmohg1mj	55	1	Although	although	IN
cord-032504-tmohg1mj	55	2	a	a	DT
cord-032504-tmohg1mj	55	3	full	full	JJ
cord-032504-tmohg1mj	55	4	review	review	NN
cord-032504-tmohg1mj	55	5	of	of	IN
cord-032504-tmohg1mj	55	6	these	these	DT
cord-032504-tmohg1mj	55	7	features	feature	NNS
cord-032504-tmohg1mj	55	8	of	of	IN
cord-032504-tmohg1mj	55	9	the	the	DT
cord-032504-tmohg1mj	55	10	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	55	11	literature	literature	NN
cord-032504-tmohg1mj	55	12	is	be	VBZ
cord-032504-tmohg1mj	55	13	beyond	beyond	IN
cord-032504-tmohg1mj	55	14	the	the	DT
cord-032504-tmohg1mj	55	15	scope	scope	NN
cord-032504-tmohg1mj	55	16	of	of	IN
cord-032504-tmohg1mj	55	17	this	this	DT
cord-032504-tmohg1mj	55	18	review	review	NN
cord-032504-tmohg1mj	55	19	,	,	,
cord-032504-tmohg1mj	55	20	we	-PRON-	PRP
cord-032504-tmohg1mj	55	21	will	will	MD
cord-032504-tmohg1mj	55	22	offer	offer	VB
cord-032504-tmohg1mj	55	23	a	a	DT
cord-032504-tmohg1mj	55	24	brief	brief	JJ
cord-032504-tmohg1mj	55	25	overview	overview	NN
cord-032504-tmohg1mj	55	26	of	of	IN
cord-032504-tmohg1mj	55	27	the	the	DT
cord-032504-tmohg1mj	55	28	main	main	JJ
cord-032504-tmohg1mj	55	29	characteristics	characteristic	NNS
cord-032504-tmohg1mj	55	30	of	of	IN
cord-032504-tmohg1mj	55	31	some	some	DT
cord-032504-tmohg1mj	55	32	of	of	IN
cord-032504-tmohg1mj	55	33	the	the	DT
cord-032504-tmohg1mj	55	34	major	major	JJ
cord-032504-tmohg1mj	55	35	models	model	NNS
cord-032504-tmohg1mj	55	36	to	to	TO
cord-032504-tmohg1mj	55	37	provide	provide	VB
cord-032504-tmohg1mj	55	38	context	context	NN
cord-032504-tmohg1mj	55	39	for	for	IN
cord-032504-tmohg1mj	55	40	the	the	DT
cord-032504-tmohg1mj	55	41	reader	reader	NN
cord-032504-tmohg1mj	55	42	[	[	-LRB-
cord-032504-tmohg1mj	55	43	25	25	CD
cord-032504-tmohg1mj	55	44	,	,	,
cord-032504-tmohg1mj	55	45	26	26	CD
cord-032504-tmohg1mj	55	46	]	]	-RRB-
cord-032504-tmohg1mj	55	47	.	.	.
cord-032504-tmohg1mj	56	1	Despite	despite	IN
cord-032504-tmohg1mj	56	2	their	-PRON-	PRP$
cord-032504-tmohg1mj	56	3	inability	inability	NN
cord-032504-tmohg1mj	56	4	to	to	TO
cord-032504-tmohg1mj	56	5	model	model	VB
cord-032504-tmohg1mj	56	6	sophisticated	sophisticated	JJ
cord-032504-tmohg1mj	56	7	cellular	cellular	JJ
cord-032504-tmohg1mj	56	8	interactions	interaction	NNS
cord-032504-tmohg1mj	56	9	,	,	,
cord-032504-tmohg1mj	56	10	in	in	IN
cord-032504-tmohg1mj	56	11	vitro	vitro	FW
cord-032504-tmohg1mj	56	12	systems	system	NNS
cord-032504-tmohg1mj	56	13	have	have	VBP
cord-032504-tmohg1mj	56	14	long	long	RB
cord-032504-tmohg1mj	56	15	been	be	VBN
cord-032504-tmohg1mj	56	16	used	use	VBN
cord-032504-tmohg1mj	56	17	as	as	IN
cord-032504-tmohg1mj	56	18	tools	tool	NNS
cord-032504-tmohg1mj	56	19	for	for	IN
cord-032504-tmohg1mj	56	20	studying	study	VBG
cord-032504-tmohg1mj	56	21	Mtb	Mtb	NNP
cord-032504-tmohg1mj	56	22	[	[	-LRB-
cord-032504-tmohg1mj	56	23	27	27	CD
cord-032504-tmohg1mj	56	24	]	]	-RRB-
cord-032504-tmohg1mj	56	25	.	.	.
cord-032504-tmohg1mj	57	1	A	a	DT
cord-032504-tmohg1mj	57	2	variety	variety	NN
cord-032504-tmohg1mj	57	3	of	of	IN
cord-032504-tmohg1mj	57	4	myeloid	myeloid	JJ
cord-032504-tmohg1mj	57	5	cell	cell	NN
cord-032504-tmohg1mj	57	6	lines	line	NNS
cord-032504-tmohg1mj	57	7	have	have	VBP
cord-032504-tmohg1mj	57	8	been	be	VBN
cord-032504-tmohg1mj	57	9	employed	employ	VBN
cord-032504-tmohg1mj	57	10	,	,	,
cord-032504-tmohg1mj	57	11	and	and	CC
cord-032504-tmohg1mj	57	12	are	be	VBP
cord-032504-tmohg1mj	57	13	often	often	RB
cord-032504-tmohg1mj	57	14	helpful	helpful	JJ
cord-032504-tmohg1mj	57	15	in	in	IN
cord-032504-tmohg1mj	57	16	quantifying	quantify	VBG
cord-032504-tmohg1mj	57	17	cytokine	cytokine	NN
cord-032504-tmohg1mj	57	18	and	and	CC
cord-032504-tmohg1mj	57	19	other	other	JJ
cord-032504-tmohg1mj	57	20	signaling	signal	VBG
cord-032504-tmohg1mj	57	21	responses	response	NNS
cord-032504-tmohg1mj	57	22	to	to	IN
cord-032504-tmohg1mj	57	23	Mtb	Mtb	NNP
cord-032504-tmohg1mj	57	24	.	.	.
cord-032504-tmohg1mj	58	1	In	in	IN
cord-032504-tmohg1mj	58	2	addition	addition	NN
cord-032504-tmohg1mj	58	3	,	,	,
cord-032504-tmohg1mj	58	4	due	due	IN
cord-032504-tmohg1mj	58	5	to	to	IN
cord-032504-tmohg1mj	58	6	the	the	DT
cord-032504-tmohg1mj	58	7	ease	ease	NN
cord-032504-tmohg1mj	58	8	with	with	IN
cord-032504-tmohg1mj	58	9	which	which	WDT
cord-032504-tmohg1mj	58	10	in	in	IN
cord-032504-tmohg1mj	58	11	vitro	vitro	FW
cord-032504-tmohg1mj	58	12	systems	system	NNS
cord-032504-tmohg1mj	58	13	can	can	MD
cord-032504-tmohg1mj	58	14	be	be	VB
cord-032504-tmohg1mj	58	15	manipulated	manipulate	VBN
cord-032504-tmohg1mj	58	16	,	,	,
cord-032504-tmohg1mj	58	17	studies	study	NNS
cord-032504-tmohg1mj	58	18	with	with	IN
cord-032504-tmohg1mj	58	19	primary	primary	JJ
cord-032504-tmohg1mj	58	20	macrophages	macrophage	NNS
cord-032504-tmohg1mj	58	21	from	from	IN
cord-032504-tmohg1mj	58	22	animal	animal	NN
cord-032504-tmohg1mj	58	23	models	model	NNS
cord-032504-tmohg1mj	58	24	have	have	VBP
cord-032504-tmohg1mj	58	25	enabled	enable	VBN
cord-032504-tmohg1mj	58	26	investigators	investigator	NNS
cord-032504-tmohg1mj	58	27	to	to	TO
cord-032504-tmohg1mj	58	28	dissect	dissect	VB
cord-032504-tmohg1mj	58	29	the	the	DT
cord-032504-tmohg1mj	58	30	roles	role	NNS
cord-032504-tmohg1mj	58	31	of	of	IN
cord-032504-tmohg1mj	58	32	individual	individual	JJ
cord-032504-tmohg1mj	58	33	proteins	protein	NNS
cord-032504-tmohg1mj	58	34	and	and	CC
cord-032504-tmohg1mj	58	35	pathways	pathway	NNS
cord-032504-tmohg1mj	58	36	in	in	IN
cord-032504-tmohg1mj	58	37	the	the	DT
cord-032504-tmohg1mj	58	38	Mtb	Mtb	NNP
cord-032504-tmohg1mj	58	39	response	response	NN
cord-032504-tmohg1mj	58	40	[	[	-LRB-
cord-032504-tmohg1mj	58	41	28	28	CD
cord-032504-tmohg1mj	58	42	,	,	,
cord-032504-tmohg1mj	58	43	29	29	CD
cord-032504-tmohg1mj	58	44	]	]	-RRB-
cord-032504-tmohg1mj	58	45	.	.	.
cord-032504-tmohg1mj	59	1	Finally	finally	RB
cord-032504-tmohg1mj	59	2	,	,	,
cord-032504-tmohg1mj	59	3	human	human	JJ
cord-032504-tmohg1mj	59	4	primary	primary	JJ
cord-032504-tmohg1mj	59	5	cells	cell	NNS
cord-032504-tmohg1mj	59	6	have	have	VBP
cord-032504-tmohg1mj	59	7	been	be	VBN
cord-032504-tmohg1mj	59	8	used	use	VBN
cord-032504-tmohg1mj	59	9	in	in	IN
cord-032504-tmohg1mj	59	10	a	a	DT
cord-032504-tmohg1mj	59	11	variety	variety	NN
cord-032504-tmohg1mj	59	12	of	of	IN
cord-032504-tmohg1mj	59	13	ways	way	NNS
cord-032504-tmohg1mj	59	14	,	,	,
cord-032504-tmohg1mj	59	15	including	include	VBG
cord-032504-tmohg1mj	59	16	induced	induce	VBN
cord-032504-tmohg1mj	59	17	pluripotent	pluripotent	JJ
cord-032504-tmohg1mj	59	18	stem	stem	NN
cord-032504-tmohg1mj	59	19	cells	cell	NNS
cord-032504-tmohg1mj	59	20	,	,	,
cord-032504-tmohg1mj	59	21	human	human	JJ
cord-032504-tmohg1mj	59	22	macrophages	macrophage	NNS
cord-032504-tmohg1mj	59	23	,	,	,
cord-032504-tmohg1mj	59	24	granuloma	granuloma	NN
cord-032504-tmohg1mj	59	25	models	model	NNS
cord-032504-tmohg1mj	59	26	,	,	,
cord-032504-tmohg1mj	59	27	and	and	CC
cord-032504-tmohg1mj	59	28	many	many	JJ
cord-032504-tmohg1mj	59	29	more	more	JJR
cord-032504-tmohg1mj	59	30	.	.	.
cord-032504-tmohg1mj	60	1	Each	each	DT
cord-032504-tmohg1mj	60	2	system	system	NN
cord-032504-tmohg1mj	60	3	has	have	VBZ
cord-032504-tmohg1mj	60	4	proven	prove	VBN
cord-032504-tmohg1mj	60	5	useful	useful	JJ
cord-032504-tmohg1mj	60	6	in	in	IN
cord-032504-tmohg1mj	60	7	addressing	address	VBG
cord-032504-tmohg1mj	60	8	different	different	JJ
cord-032504-tmohg1mj	60	9	aspects	aspect	NNS
cord-032504-tmohg1mj	60	10	of	of	IN
cord-032504-tmohg1mj	60	11	the	the	DT
cord-032504-tmohg1mj	60	12	Mtb	Mtb	NNP
cord-032504-tmohg1mj	60	13	response	response	NN
cord-032504-tmohg1mj	60	14	,	,	,
cord-032504-tmohg1mj	60	15	but	but	CC
cord-032504-tmohg1mj	60	16	all	all	DT
cord-032504-tmohg1mj	60	17	are	be	VBP
cord-032504-tmohg1mj	60	18	hampered	hamper	VBN
cord-032504-tmohg1mj	60	19	by	by	IN
cord-032504-tmohg1mj	60	20	their	-PRON-	PRP$
cord-032504-tmohg1mj	60	21	inability	inability	NN
cord-032504-tmohg1mj	60	22	to	to	TO
cord-032504-tmohg1mj	60	23	coordinate	coordinate	VB
cord-032504-tmohg1mj	60	24	the	the	DT
cord-032504-tmohg1mj	60	25	full	full	JJ
cord-032504-tmohg1mj	60	26	spectrum	spectrum	NN
cord-032504-tmohg1mj	60	27	of	of	IN
cord-032504-tmohg1mj	60	28	in	in	IN
cord-032504-tmohg1mj	60	29	vivo	vivo	NN
cord-032504-tmohg1mj	60	30	responses	response	NNS
cord-032504-tmohg1mj	60	31	.	.	.
cord-032504-tmohg1mj	61	1	An	an	DT
cord-032504-tmohg1mj	61	2	additional	additional	JJ
cord-032504-tmohg1mj	61	3	challenge	challenge	NN
cord-032504-tmohg1mj	61	4	is	be	VBZ
cord-032504-tmohg1mj	61	5	the	the	DT
cord-032504-tmohg1mj	61	6	conflation	conflation	NN
cord-032504-tmohg1mj	61	7	of	of	IN
cord-032504-tmohg1mj	61	8	different	different	JJ
cord-032504-tmohg1mj	61	9	types	type	NNS
cord-032504-tmohg1mj	61	10	of	of	IN
cord-032504-tmohg1mj	61	11	macrophages	macrophage	NNS
cord-032504-tmohg1mj	61	12	,	,	,
cord-032504-tmohg1mj	61	13	whether	whether	IN
cord-032504-tmohg1mj	61	14	from	from	IN
cord-032504-tmohg1mj	61	15	cell	cell	NN
cord-032504-tmohg1mj	61	16	-	-	HYPH
cord-032504-tmohg1mj	61	17	lines	line	NNS
cord-032504-tmohg1mj	61	18	,	,	,
cord-032504-tmohg1mj	61	19	animal	animal	NN
cord-032504-tmohg1mj	61	20	models	model	NNS
cord-032504-tmohg1mj	61	21	,	,	,
cord-032504-tmohg1mj	61	22	or	or	CC
cord-032504-tmohg1mj	61	23	humans	human	NNS
cord-032504-tmohg1mj	61	24	,	,	,
cord-032504-tmohg1mj	61	25	as	as	IN
cord-032504-tmohg1mj	61	26	a	a	DT
cord-032504-tmohg1mj	61	27	homogenous	homogenous	JJ
cord-032504-tmohg1mj	61	28	population	population	NN
cord-032504-tmohg1mj	61	29	.	.	.
cord-032504-tmohg1mj	62	1	Rather	rather	RB
cord-032504-tmohg1mj	62	2	,	,	,
cord-032504-tmohg1mj	62	3	there	there	EX
cord-032504-tmohg1mj	62	4	is	be	VBZ
cord-032504-tmohg1mj	62	5	a	a	DT
cord-032504-tmohg1mj	62	6	growing	grow	VBG
cord-032504-tmohg1mj	62	7	appreciation	appreciation	NN
cord-032504-tmohg1mj	62	8	of	of	IN
cord-032504-tmohg1mj	62	9	the	the	DT
cord-032504-tmohg1mj	62	10	distinctions	distinction	NNS
cord-032504-tmohg1mj	62	11	between	between	IN
cord-032504-tmohg1mj	62	12	tissue	tissue	NN
cord-032504-tmohg1mj	62	13	-	-	HYPH
cord-032504-tmohg1mj	62	14	derived	derive	VBN
cord-032504-tmohg1mj	62	15	and	and	CC
cord-032504-tmohg1mj	62	16	bone	bone	NN
cord-032504-tmohg1mj	62	17	-	-	HYPH
cord-032504-tmohg1mj	62	18	marrow	marrow	NN
cord-032504-tmohg1mj	62	19	derived	derive	VBN
cord-032504-tmohg1mj	62	20	macrophages	macrophage	NNS
cord-032504-tmohg1mj	62	21	,	,	,
cord-032504-tmohg1mj	62	22	from	from	IN
cord-032504-tmohg1mj	62	23	their	-PRON-	PRP$
cord-032504-tmohg1mj	62	24	ontogeny	ontogeny	NN
cord-032504-tmohg1mj	62	25	to	to	IN
cord-032504-tmohg1mj	62	26	functional	functional	JJ
cord-032504-tmohg1mj	62	27	capacity	capacity	NN
cord-032504-tmohg1mj	62	28	and	and	CC
cord-032504-tmohg1mj	62	29	self	self	NN
cord-032504-tmohg1mj	62	30	-	-	HYPH
cord-032504-tmohg1mj	62	31	maintenance	maintenance	NN
cord-032504-tmohg1mj	62	32	[	[	-LRB-
cord-032504-tmohg1mj	62	33	30	30	CD
cord-032504-tmohg1mj	62	34	]	]	-RRB-
cord-032504-tmohg1mj	62	35	[	[	-LRB-
cord-032504-tmohg1mj	62	36	31	31	CD
cord-032504-tmohg1mj	62	37	]	]	-RRB-
cord-032504-tmohg1mj	62	38	[	[	-LRB-
cord-032504-tmohg1mj	62	39	32	32	CD
cord-032504-tmohg1mj	62	40	]	]	-RRB-
cord-032504-tmohg1mj	62	41	.	.	.
cord-032504-tmohg1mj	63	1	These	these	DT
cord-032504-tmohg1mj	63	2	distinctions	distinction	NNS
cord-032504-tmohg1mj	63	3	are	be	VBP
cord-032504-tmohg1mj	63	4	highly	highly	RB
cord-032504-tmohg1mj	63	5	relevant	relevant	JJ
cord-032504-tmohg1mj	63	6	to	to	IN
cord-032504-tmohg1mj	63	7	this	this	DT
cord-032504-tmohg1mj	63	8	review	review	NN
cord-032504-tmohg1mj	63	9	,	,	,
cord-032504-tmohg1mj	63	10	as	as	IN
cord-032504-tmohg1mj	63	11	bone	bone	NN
cord-032504-tmohg1mj	63	12	-	-	HYPH
cord-032504-tmohg1mj	63	13	marrow	marrow	NN
cord-032504-tmohg1mj	63	14	derived	derive	VBN
cord-032504-tmohg1mj	63	15	macrophages	macrophage	NNS
cord-032504-tmohg1mj	63	16	do	do	VBP
cord-032504-tmohg1mj	63	17	not	not	RB
cord-032504-tmohg1mj	63	18	become	become	VB
cord-032504-tmohg1mj	63	19	polarized	polarized	JJ
cord-032504-tmohg1mj	63	20	in	in	IN
cord-032504-tmohg1mj	63	21	the	the	DT
cord-032504-tmohg1mj	63	22	same	same	JJ
cord-032504-tmohg1mj	63	23	manner	manner	NN
cord-032504-tmohg1mj	63	24	as	as	IN
cord-032504-tmohg1mj	63	25	alveolar	alveolar	NN
cord-032504-tmohg1mj	63	26	macrophages	macrophage	NNS
cord-032504-tmohg1mj	63	27	following	follow	VBG
cord-032504-tmohg1mj	63	28	Mtb	Mtb	NNP
cord-032504-tmohg1mj	63	29	exposure	exposure	NN
cord-032504-tmohg1mj	63	30	,	,	,
cord-032504-tmohg1mj	63	31	and	and	CC
cord-032504-tmohg1mj	63	32	thus	thus	RB
cord-032504-tmohg1mj	63	33	can	can	MD
cord-032504-tmohg1mj	63	34	not	not	RB
cord-032504-tmohg1mj	63	35	be	be	VB
cord-032504-tmohg1mj	63	36	expected	expect	VBN
cord-032504-tmohg1mj	63	37	to	to	TO
cord-032504-tmohg1mj	63	38	behave	behave	VB
cord-032504-tmohg1mj	63	39	the	the	DT
cord-032504-tmohg1mj	63	40	same	same	JJ
cord-032504-tmohg1mj	63	41	[	[	-LRB-
cord-032504-tmohg1mj	63	42	33	33	CD
cord-032504-tmohg1mj	63	43	]	]	-RRB-
cord-032504-tmohg1mj	63	44	.	.	.
cord-032504-tmohg1mj	64	1	However	however	RB
cord-032504-tmohg1mj	64	2	,	,	,
cord-032504-tmohg1mj	64	3	given	give	VBN
cord-032504-tmohg1mj	64	4	challenges	challenge	NNS
cord-032504-tmohg1mj	64	5	in	in	IN
cord-032504-tmohg1mj	64	6	obtaining	obtain	VBG
cord-032504-tmohg1mj	64	7	primary	primary	JJ
cord-032504-tmohg1mj	64	8	alveolar	alveolar	NN
cord-032504-tmohg1mj	64	9	macrophages	macrophage	NNS
cord-032504-tmohg1mj	64	10	,	,	,
cord-032504-tmohg1mj	64	11	particularly	particularly	RB
cord-032504-tmohg1mj	64	12	from	from	IN
cord-032504-tmohg1mj	64	13	humans	human	NNS
cord-032504-tmohg1mj	64	14	[	[	-LRB-
cord-032504-tmohg1mj	64	15	34	34	CD
cord-032504-tmohg1mj	64	16	]	]	-RRB-
cord-032504-tmohg1mj	64	17	,	,	,
cord-032504-tmohg1mj	64	18	many	many	JJ
cord-032504-tmohg1mj	64	19	studies	study	NNS
cord-032504-tmohg1mj	64	20	are	be	VBP
cord-032504-tmohg1mj	64	21	conducted	conduct	VBN
cord-032504-tmohg1mj	64	22	with	with	IN
cord-032504-tmohg1mj	64	23	derived	derive	VBN
cord-032504-tmohg1mj	64	24	cells	cell	NNS
cord-032504-tmohg1mj	64	25	.	.	.
cord-032504-tmohg1mj	65	1	With	with	IN
cord-032504-tmohg1mj	65	2	regards	regard	NNS
cord-032504-tmohg1mj	65	3	to	to	IN
cord-032504-tmohg1mj	65	4	animal	animal	NN
cord-032504-tmohg1mj	65	5	systems	system	NNS
cord-032504-tmohg1mj	65	6	,	,	,
cord-032504-tmohg1mj	65	7	ease	ease	NN
cord-032504-tmohg1mj	65	8	of	of	IN
cord-032504-tmohg1mj	65	9	use	use	NN
cord-032504-tmohg1mj	65	10	in	in	IN
cord-032504-tmohg1mj	65	11	handling	handle	VBG
cord-032504-tmohg1mj	65	12	the	the	DT
cord-032504-tmohg1mj	65	13	zebrafish	zebrafish	NN
cord-032504-tmohg1mj	65	14	-	-	:
cord-032504-tmohg1mj	65	15	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	65	16	marinum	marinum	NN
cord-032504-tmohg1mj	65	17	model	model	NN
cord-032504-tmohg1mj	65	18	has	have	VBZ
cord-032504-tmohg1mj	65	19	made	make	VBN
cord-032504-tmohg1mj	65	20	it	-PRON-	PRP
cord-032504-tmohg1mj	65	21	a	a	DT
cord-032504-tmohg1mj	65	22	powerful	powerful	JJ
cord-032504-tmohg1mj	65	23	tool	tool	NN
cord-032504-tmohg1mj	65	24	for	for	IN
cord-032504-tmohg1mj	65	25	the	the	DT
cord-032504-tmohg1mj	65	26	study	study	NN
cord-032504-tmohg1mj	65	27	of	of	IN
cord-032504-tmohg1mj	65	28	Mtb	Mtb	NNP
cord-032504-tmohg1mj	65	29	[	[	-LRB-
cord-032504-tmohg1mj	65	30	35	35	CD
cord-032504-tmohg1mj	65	31	]	]	-RRB-
cord-032504-tmohg1mj	65	32	.	.	.
cord-032504-tmohg1mj	66	1	Several	several	JJ
cord-032504-tmohg1mj	66	2	key	key	JJ
cord-032504-tmohg1mj	66	3	components	component	NNS
cord-032504-tmohg1mj	66	4	of	of	IN
cord-032504-tmohg1mj	66	5	the	the	DT
cord-032504-tmohg1mj	66	6	human	human	JJ
cord-032504-tmohg1mj	66	7	response	response	NN
cord-032504-tmohg1mj	66	8	to	to	IN
cord-032504-tmohg1mj	66	9	Mtb	Mtb	NNP
cord-032504-tmohg1mj	66	10	are	be	VBP
cord-032504-tmohg1mj	66	11	present	present	JJ
cord-032504-tmohg1mj	66	12	in	in	IN
cord-032504-tmohg1mj	66	13	zebrafish	zebrafish	NN
cord-032504-tmohg1mj	66	14	,	,	,
cord-032504-tmohg1mj	66	15	including	include	VBG
cord-032504-tmohg1mj	66	16	the	the	DT
cord-032504-tmohg1mj	66	17	leukotriene	leukotriene	JJ
cord-032504-tmohg1mj	66	18	A4	A4	NNP
cord-032504-tmohg1mj	66	19	hydrolase	hydrolase	NN
cord-032504-tmohg1mj	66	20	locus	locus	NN
cord-032504-tmohg1mj	66	21	,	,	,
cord-032504-tmohg1mj	66	22	and	and	CC
cord-032504-tmohg1mj	66	23	it	-PRON-	PRP
cord-032504-tmohg1mj	66	24	has	have	VBZ
cord-032504-tmohg1mj	66	25	been	be	VBN
cord-032504-tmohg1mj	66	26	used	use	VBN
cord-032504-tmohg1mj	66	27	to	to	TO
cord-032504-tmohg1mj	66	28	study	study	VB
cord-032504-tmohg1mj	66	29	everything	everything	NN
cord-032504-tmohg1mj	66	30	from	from	IN
cord-032504-tmohg1mj	66	31	treatment	treatment	NN
cord-032504-tmohg1mj	66	32	strategies	strategy	NNS
cord-032504-tmohg1mj	66	33	for	for	IN
cord-032504-tmohg1mj	66	34	drug	drug	NN
cord-032504-tmohg1mj	66	35	-	-	HYPH
cord-032504-tmohg1mj	66	36	resistant	resistant	JJ
cord-032504-tmohg1mj	66	37	Mtb	Mtb	NNP
cord-032504-tmohg1mj	66	38	to	to	IN
cord-032504-tmohg1mj	66	39	vaccine	vaccine	NN
cord-032504-tmohg1mj	66	40	development	development	NN
cord-032504-tmohg1mj	66	41	.	.	.
cord-032504-tmohg1mj	67	1	The	the	DT
cord-032504-tmohg1mj	67	2	mouse	mouse	NN
cord-032504-tmohg1mj	67	3	model	model	NN
cord-032504-tmohg1mj	67	4	has	have	VBZ
cord-032504-tmohg1mj	67	5	the	the	DT
cord-032504-tmohg1mj	67	6	virtue	virtue	NN
cord-032504-tmohg1mj	67	7	of	of	IN
cord-032504-tmohg1mj	67	8	capturing	capture	VBG
cord-032504-tmohg1mj	67	9	vertebrate	vertebrate	JJ
cord-032504-tmohg1mj	67	10	,	,	,
cord-032504-tmohg1mj	67	11	mammalian	mammalian	JJ
cord-032504-tmohg1mj	67	12	immune	immune	JJ
cord-032504-tmohg1mj	67	13	responses	response	NNS
cord-032504-tmohg1mj	67	14	in	in	IN
cord-032504-tmohg1mj	67	15	a	a	DT
cord-032504-tmohg1mj	67	16	reproducible	reproducible	JJ
cord-032504-tmohg1mj	67	17	,	,	,
cord-032504-tmohg1mj	67	18	easily	easily	RB
cord-032504-tmohg1mj	67	19	scalable	scalable	JJ
cord-032504-tmohg1mj	67	20	system	system	NN
cord-032504-tmohg1mj	67	21	.	.	.
cord-032504-tmohg1mj	68	1	However	however	RB
cord-032504-tmohg1mj	68	2	,	,	,
cord-032504-tmohg1mj	68	3	different	different	JJ
cord-032504-tmohg1mj	68	4	mouse	mouse	NN
cord-032504-tmohg1mj	68	5	strains	strain	NNS
cord-032504-tmohg1mj	68	6	have	have	VBP
cord-032504-tmohg1mj	68	7	different	different	JJ
cord-032504-tmohg1mj	68	8	levels	level	NNS
cord-032504-tmohg1mj	68	9	of	of	IN
cord-032504-tmohg1mj	68	10	susceptibility	susceptibility	NN
cord-032504-tmohg1mj	68	11	to	to	IN
cord-032504-tmohg1mj	68	12	Mtb	Mtb	NNP
cord-032504-tmohg1mj	68	13	and	and	CC
cord-032504-tmohg1mj	68	14	mice	mouse	NNS
cord-032504-tmohg1mj	68	15	do	do	VBP
cord-032504-tmohg1mj	68	16	not	not	RB
cord-032504-tmohg1mj	68	17	typically	typically	RB
cord-032504-tmohg1mj	68	18	form	form	VB
cord-032504-tmohg1mj	68	19	granulomas	granuloma	NNS
cord-032504-tmohg1mj	68	20	or	or	CC
cord-032504-tmohg1mj	68	21	cavities	cavity	NNS
cord-032504-tmohg1mj	68	22	[	[	-LRB-
cord-032504-tmohg1mj	68	23	36	36	CD
cord-032504-tmohg1mj	68	24	]	]	-RRB-
cord-032504-tmohg1mj	68	25	.	.	.
cord-032504-tmohg1mj	69	1	As	as	IN
cord-032504-tmohg1mj	69	2	a	a	DT
cord-032504-tmohg1mj	69	3	result	result	NN
cord-032504-tmohg1mj	69	4	,	,	,
cord-032504-tmohg1mj	69	5	the	the	DT
cord-032504-tmohg1mj	69	6	mouse	mouse	NN
cord-032504-tmohg1mj	69	7	model	model	NN
cord-032504-tmohg1mj	69	8	tends	tend	VBZ
cord-032504-tmohg1mj	69	9	to	to	TO
cord-032504-tmohg1mj	69	10	be	be	VB
cord-032504-tmohg1mj	69	11	suited	suit	VBN
cord-032504-tmohg1mj	69	12	for	for	IN
cord-032504-tmohg1mj	69	13	studies	study	NNS
cord-032504-tmohg1mj	69	14	of	of	IN
cord-032504-tmohg1mj	69	15	cell	cell	NN
cord-032504-tmohg1mj	69	16	-	-	HYPH
cord-032504-tmohg1mj	69	17	mediated	mediate	VBN
cord-032504-tmohg1mj	69	18	immunity	immunity	NN
cord-032504-tmohg1mj	69	19	and	and	CC
cord-032504-tmohg1mj	69	20	drug	drug	NN
cord-032504-tmohg1mj	69	21	development	development	NN
cord-032504-tmohg1mj	69	22	,	,	,
cord-032504-tmohg1mj	69	23	but	but	CC
cord-032504-tmohg1mj	69	24	less	less	RBR
cord-032504-tmohg1mj	69	25	useful	useful	JJ
cord-032504-tmohg1mj	69	26	for	for	IN
cord-032504-tmohg1mj	69	27	studies	study	NNS
cord-032504-tmohg1mj	69	28	of	of	IN
cord-032504-tmohg1mj	69	29	human	human	JJ
cord-032504-tmohg1mj	69	30	clinical	clinical	JJ
cord-032504-tmohg1mj	69	31	outcomes	outcome	NNS
cord-032504-tmohg1mj	69	32	[	[	-LRB-
cord-032504-tmohg1mj	69	33	37	37	CD
cord-032504-tmohg1mj	69	34	]	]	-RRB-
cord-032504-tmohg1mj	69	35	.	.	.
cord-032504-tmohg1mj	70	1	Guinea	guinea	NN
cord-032504-tmohg1mj	70	2	pigs	pig	NNS
cord-032504-tmohg1mj	70	3	provide	provide	VBP
cord-032504-tmohg1mj	70	4	another	another	DT
cord-032504-tmohg1mj	70	5	small	small	JJ
cord-032504-tmohg1mj	70	6	animal	animal	NN
cord-032504-tmohg1mj	70	7	model	model	NN
cord-032504-tmohg1mj	70	8	,	,	,
cord-032504-tmohg1mj	70	9	with	with	IN
cord-032504-tmohg1mj	70	10	the	the	DT
cord-032504-tmohg1mj	70	11	benefit	benefit	NN
cord-032504-tmohg1mj	70	12	of	of	IN
cord-032504-tmohg1mj	70	13	recapitulating	recapitulate	VBG
cord-032504-tmohg1mj	70	14	lung	lung	NN
cord-032504-tmohg1mj	70	15	necrosis	necrosis	NN
cord-032504-tmohg1mj	70	16	and	and	CC
cord-032504-tmohg1mj	70	17	other	other	JJ
cord-032504-tmohg1mj	70	18	human	human	JJ
cord-032504-tmohg1mj	70	19	features	feature	NNS
cord-032504-tmohg1mj	70	20	,	,	,
cord-032504-tmohg1mj	70	21	but	but	CC
cord-032504-tmohg1mj	70	22	challenges	challenge	NNS
cord-032504-tmohg1mj	70	23	in	in	IN
cord-032504-tmohg1mj	70	24	measuring	measure	VBG
cord-032504-tmohg1mj	70	25	their	-PRON-	PRP$
cord-032504-tmohg1mj	70	26	immune	immune	JJ
cord-032504-tmohg1mj	70	27	responses	response	NNS
cord-032504-tmohg1mj	70	28	has	have	VBZ
cord-032504-tmohg1mj	70	29	historically	historically	RB
cord-032504-tmohg1mj	70	30	limited	limit	VBN
cord-032504-tmohg1mj	70	31	their	-PRON-	PRP$
cord-032504-tmohg1mj	70	32	widespread	widespread	JJ
cord-032504-tmohg1mj	70	33	use	use	NN
cord-032504-tmohg1mj	70	34	[	[	-LRB-
cord-032504-tmohg1mj	70	35	25	25	CD
cord-032504-tmohg1mj	70	36	]	]	-RRB-
cord-032504-tmohg1mj	70	37	.	.	.
cord-032504-tmohg1mj	71	1	Rabbits	rabbit	NNS
cord-032504-tmohg1mj	71	2	have	have	VBP
cord-032504-tmohg1mj	71	3	also	also	RB
cord-032504-tmohg1mj	71	4	provided	provide	VBN
cord-032504-tmohg1mj	71	5	an	an	DT
cord-032504-tmohg1mj	71	6	effective	effective	JJ
cord-032504-tmohg1mj	71	7	model	model	NN
cord-032504-tmohg1mj	71	8	system	system	NN
cord-032504-tmohg1mj	71	9	for	for	IN
cord-032504-tmohg1mj	71	10	Mtb	Mtb	NNP
cord-032504-tmohg1mj	71	11	research	research	NN
cord-032504-tmohg1mj	71	12	,	,	,
cord-032504-tmohg1mj	71	13	largely	largely	RB
cord-032504-tmohg1mj	71	14	due	due	JJ
cord-032504-tmohg1mj	71	15	to	to	IN
cord-032504-tmohg1mj	71	16	the	the	DT
cord-032504-tmohg1mj	71	17	fact	fact	NN
cord-032504-tmohg1mj	71	18	that	that	IN
cord-032504-tmohg1mj	71	19	the	the	DT
cord-032504-tmohg1mj	71	20	structural	structural	JJ
cord-032504-tmohg1mj	71	21	similarities	similarity	NNS
cord-032504-tmohg1mj	71	22	between	between	IN
cord-032504-tmohg1mj	71	23	their	-PRON-	PRP$
cord-032504-tmohg1mj	71	24	lungs	lung	NNS
cord-032504-tmohg1mj	71	25	and	and	CC
cord-032504-tmohg1mj	71	26	human	human	JJ
cord-032504-tmohg1mj	71	27	lungs	lung	NNS
cord-032504-tmohg1mj	71	28	leads	lead	VBZ
cord-032504-tmohg1mj	71	29	to	to	IN
cord-032504-tmohg1mj	71	30	similar	similar	JJ
cord-032504-tmohg1mj	71	31	pathology	pathology	NN
cord-032504-tmohg1mj	71	32	in	in	IN
cord-032504-tmohg1mj	71	33	response	response	NN
cord-032504-tmohg1mj	71	34	to	to	IN
cord-032504-tmohg1mj	71	35	Mtb	Mtb	NNP
cord-032504-tmohg1mj	71	36	.	.	.
cord-032504-tmohg1mj	72	1	That	that	DT
cord-032504-tmohg1mj	72	2	said	say	VBD
cord-032504-tmohg1mj	72	3	,	,	,
cord-032504-tmohg1mj	72	4	their	-PRON-	PRP$
cord-032504-tmohg1mj	72	5	larger	large	JJR
cord-032504-tmohg1mj	72	6	size	size	NN
cord-032504-tmohg1mj	72	7	and	and	CC
cord-032504-tmohg1mj	72	8	the	the	DT
cord-032504-tmohg1mj	72	9	greater	great	JJR
cord-032504-tmohg1mj	72	10	resources	resource	NNS
cord-032504-tmohg1mj	72	11	required	require	VBN
cord-032504-tmohg1mj	72	12	to	to	TO
cord-032504-tmohg1mj	72	13	utilize	utilize	VB
cord-032504-tmohg1mj	72	14	them	-PRON-	PRP
cord-032504-tmohg1mj	72	15	has	have	VBZ
cord-032504-tmohg1mj	72	16	limited	limit	VBN
cord-032504-tmohg1mj	72	17	their	-PRON-	PRP$
cord-032504-tmohg1mj	72	18	broad	broad	JJ
cord-032504-tmohg1mj	72	19	applicability	applicability	NN
cord-032504-tmohg1mj	72	20	[	[	-LRB-
cord-032504-tmohg1mj	72	21	36	36	CD
cord-032504-tmohg1mj	72	22	,	,	,
cord-032504-tmohg1mj	72	23	38	38	CD
cord-032504-tmohg1mj	72	24	]	]	-RRB-
cord-032504-tmohg1mj	72	25	.	.	.
cord-032504-tmohg1mj	73	1	Finally	finally	RB
cord-032504-tmohg1mj	73	2	,	,	,
cord-032504-tmohg1mj	73	3	non	non	JJ
cord-032504-tmohg1mj	73	4	-	-	JJ
cord-032504-tmohg1mj	73	5	human	human	JJ
cord-032504-tmohg1mj	73	6	primates	primate	NNS
cord-032504-tmohg1mj	73	7	,	,	,
cord-032504-tmohg1mj	73	8	particularly	particularly	RB
cord-032504-tmohg1mj	73	9	rhesus	rhesu	NNS
cord-032504-tmohg1mj	73	10	and	and	CC
cord-032504-tmohg1mj	73	11	cynomolgus	cynomolgus	JJ
cord-032504-tmohg1mj	73	12	macaques	macaque	NNS
cord-032504-tmohg1mj	73	13	,	,	,
cord-032504-tmohg1mj	73	14	have	have	VBP
cord-032504-tmohg1mj	73	15	marked	mark	VBN
cord-032504-tmohg1mj	73	16	genetic	genetic	JJ
cord-032504-tmohg1mj	73	17	and	and	CC
cord-032504-tmohg1mj	73	18	immunologic	immunologic	JJ
cord-032504-tmohg1mj	73	19	similarities	similarity	NNS
cord-032504-tmohg1mj	73	20	to	to	IN
cord-032504-tmohg1mj	73	21	humans	human	NNS
cord-032504-tmohg1mj	73	22	and	and	CC
cord-032504-tmohg1mj	73	23	,	,	,
cord-032504-tmohg1mj	73	24	as	as	IN
cord-032504-tmohg1mj	73	25	such	such	JJ
cord-032504-tmohg1mj	73	26	,	,	,
cord-032504-tmohg1mj	73	27	have	have	VBP
cord-032504-tmohg1mj	73	28	yielded	yield	VBN
cord-032504-tmohg1mj	73	29	significant	significant	JJ
cord-032504-tmohg1mj	73	30	advances	advance	NNS
cord-032504-tmohg1mj	73	31	in	in	IN
cord-032504-tmohg1mj	73	32	our	-PRON-	PRP$
cord-032504-tmohg1mj	73	33	understanding	understanding	NN
cord-032504-tmohg1mj	73	34	of	of	IN
cord-032504-tmohg1mj	73	35	host	host	NN
cord-032504-tmohg1mj	73	36	-	-	HYPH
cord-032504-tmohg1mj	73	37	pathogen	pathogen	NN
cord-032504-tmohg1mj	73	38	interactions	interaction	NNS
cord-032504-tmohg1mj	73	39	and	and	CC
cord-032504-tmohg1mj	73	40	the	the	DT
cord-032504-tmohg1mj	73	41	potential	potential	NN
cord-032504-tmohg1mj	73	42	for	for	IN
cord-032504-tmohg1mj	73	43	vaccineinduced	vaccineinduced	NNP
cord-032504-tmohg1mj	73	44	protection	protection	NN
cord-032504-tmohg1mj	73	45	in	in	IN
cord-032504-tmohg1mj	73	46	recent	recent	JJ
cord-032504-tmohg1mj	73	47	years	year	NNS
cord-032504-tmohg1mj	73	48	[	[	-LRB-
cord-032504-tmohg1mj	73	49	39	39	CD
cord-032504-tmohg1mj	73	50	,	,	,
cord-032504-tmohg1mj	73	51	40	40	CD
cord-032504-tmohg1mj	73	52	]	]	-RRB-
cord-032504-tmohg1mj	73	53	.	.	.
cord-032504-tmohg1mj	74	1	However	however	RB
cord-032504-tmohg1mj	74	2	,	,	,
cord-032504-tmohg1mj	74	3	given	give	VBN
cord-032504-tmohg1mj	74	4	the	the	DT
cord-032504-tmohg1mj	74	5	vast	vast	JJ
cord-032504-tmohg1mj	74	6	resources	resource	NNS
cord-032504-tmohg1mj	74	7	needed	need	VBN
cord-032504-tmohg1mj	74	8	to	to	TO
cord-032504-tmohg1mj	74	9	sustain	sustain	VB
cord-032504-tmohg1mj	74	10	these	these	DT
cord-032504-tmohg1mj	74	11	animals	animal	NNS
cord-032504-tmohg1mj	74	12	,	,	,
cord-032504-tmohg1mj	74	13	there	there	EX
cord-032504-tmohg1mj	74	14	are	be	VBP
cord-032504-tmohg1mj	74	15	a	a	DT
cord-032504-tmohg1mj	74	16	limited	limited	JJ
cord-032504-tmohg1mj	74	17	number	number	NN
cord-032504-tmohg1mj	74	18	of	of	IN
cord-032504-tmohg1mj	74	19	research	research	NN
cord-032504-tmohg1mj	74	20	centers	center	NNS
cord-032504-tmohg1mj	74	21	capable	capable	JJ
cord-032504-tmohg1mj	74	22	of	of	IN
cord-032504-tmohg1mj	74	23	conducting	conduct	VBG
cord-032504-tmohg1mj	74	24	non	non	JJ
cord-032504-tmohg1mj	74	25	-	-	JJ
cord-032504-tmohg1mj	74	26	human	human	JJ
cord-032504-tmohg1mj	74	27	primate	primate	JJ
cord-032504-tmohg1mj	74	28	studies	study	NNS
cord-032504-tmohg1mj	74	29	.	.	.
cord-032504-tmohg1mj	75	1	While	while	IN
cord-032504-tmohg1mj	75	2	in	in	IN
cord-032504-tmohg1mj	75	3	-	-	HYPH
cord-032504-tmohg1mj	75	4	depth	depth	NN
cord-032504-tmohg1mj	75	5	analysis	analysis	NN
cord-032504-tmohg1mj	75	6	of	of	IN
cord-032504-tmohg1mj	75	7	early	early	JJ
cord-032504-tmohg1mj	75	8	immunologic	immunologic	JJ
cord-032504-tmohg1mj	75	9	events	event	NNS
cord-032504-tmohg1mj	75	10	in	in	IN
cord-032504-tmohg1mj	75	11	human	human	JJ
cord-032504-tmohg1mj	75	12	Mtb	Mtb	NNP
cord-032504-tmohg1mj	75	13	infection	infection	NN
cord-032504-tmohg1mj	75	14	remains	remain	VBZ
cord-032504-tmohg1mj	75	15	challenging	challenge	VBG
cord-032504-tmohg1mj	75	16	for	for	IN
cord-032504-tmohg1mj	75	17	the	the	DT
cord-032504-tmohg1mj	75	18	reasons	reason	NNS
cord-032504-tmohg1mj	75	19	discussed	discuss	VBN
cord-032504-tmohg1mj	75	20	above	above	RB
cord-032504-tmohg1mj	75	21	,	,	,
cord-032504-tmohg1mj	75	22	Poulsen	Poulsen	NNP
cord-032504-tmohg1mj	75	23	and	and	CC
cord-032504-tmohg1mj	75	24	others	other	NNS
cord-032504-tmohg1mj	75	25	established	establish	VBD
cord-032504-tmohg1mj	75	26	over	over	IN
cord-032504-tmohg1mj	75	27	50	50	CD
cord-032504-tmohg1mj	75	28	years	year	NNS
cord-032504-tmohg1mj	75	29	ago	ago	RB
cord-032504-tmohg1mj	75	30	that	that	DT
cord-032504-tmohg1mj	75	31	tuberculin	tuberculin	NN
cord-032504-tmohg1mj	75	32	skin	skin	NN
cord-032504-tmohg1mj	75	33	test	test	NN
cord-032504-tmohg1mj	75	34	(	(	-LRB-
cord-032504-tmohg1mj	75	35	TST	TST	NNP
cord-032504-tmohg1mj	75	36	)	)	-RRB-
cord-032504-tmohg1mj	75	37	conversion	conversion	NN
cord-032504-tmohg1mj	75	38	in	in	IN
cord-032504-tmohg1mj	75	39	humans	human	NNS
cord-032504-tmohg1mj	75	40	,	,	,
cord-032504-tmohg1mj	75	41	an	an	DT
cord-032504-tmohg1mj	75	42	indicator	indicator	NN
cord-032504-tmohg1mj	75	43	of	of	IN
cord-032504-tmohg1mj	75	44	the	the	DT
cord-032504-tmohg1mj	75	45	onset	onset	NN
cord-032504-tmohg1mj	75	46	of	of	IN
cord-032504-tmohg1mj	75	47	the	the	DT
cord-032504-tmohg1mj	75	48	adaptive	adaptive	JJ
cord-032504-tmohg1mj	75	49	immune	immune	JJ
cord-032504-tmohg1mj	75	50	response	response	NN
cord-032504-tmohg1mj	75	51	,	,	,
cord-032504-tmohg1mj	75	52	generally	generally	RB
cord-032504-tmohg1mj	75	53	occurred	occur	VBN
cord-032504-tmohg1mj	75	54	by	by	IN
cord-032504-tmohg1mj	75	55	6	6	CD
cord-032504-tmohg1mj	75	56	weeks	week	NNS
cord-032504-tmohg1mj	75	57	after	after	IN
cord-032504-tmohg1mj	75	58	exposure	exposure	NN
cord-032504-tmohg1mj	75	59	[	[	-LRB-
cord-032504-tmohg1mj	75	60	41	41	CD
cord-032504-tmohg1mj	75	61	]	]	-RRB-
cord-032504-tmohg1mj	76	1	[	[	-LRB-
cord-032504-tmohg1mj	76	2	42	42	CD
cord-032504-tmohg1mj	76	3	]	]	-RRB-
cord-032504-tmohg1mj	76	4	[	[	-LRB-
cord-032504-tmohg1mj	76	5	43	43	CD
cord-032504-tmohg1mj	76	6	]	]	-RRB-
cord-032504-tmohg1mj	76	7	.	.	.
cord-032504-tmohg1mj	77	1	Poulsen	Poulsen	NNP
cord-032504-tmohg1mj	77	2	also	also	RB
cord-032504-tmohg1mj	77	3	determined	determine	VBD
cord-032504-tmohg1mj	77	4	that	that	IN
cord-032504-tmohg1mj	77	5	this	this	DT
cord-032504-tmohg1mj	77	6	period	period	NN
cord-032504-tmohg1mj	77	7	prior	prior	RB
cord-032504-tmohg1mj	77	8	to	to	IN
cord-032504-tmohg1mj	77	9	TST	TST	NNP
cord-032504-tmohg1mj	77	10	conversion	conversion	NN
cord-032504-tmohg1mj	77	11	is	be	VBZ
cord-032504-tmohg1mj	77	12	not	not	RB
cord-032504-tmohg1mj	77	13	a	a	DT
cord-032504-tmohg1mj	77	14	time	time	NN
cord-032504-tmohg1mj	77	15	of	of	IN
cord-032504-tmohg1mj	77	16	immunologic	immunologic	JJ
cord-032504-tmohg1mj	77	17	quiescence	quiescence	NN
cord-032504-tmohg1mj	77	18	;	;	:
cord-032504-tmohg1mj	77	19	rather	rather	RB
cord-032504-tmohg1mj	77	20	,	,	,
cord-032504-tmohg1mj	77	21	many	many	JJ
cord-032504-tmohg1mj	77	22	individuals	individual	NNS
cord-032504-tmohg1mj	77	23	had	have	VBD
cord-032504-tmohg1mj	77	24	evidence	evidence	NN
cord-032504-tmohg1mj	77	25	of	of	IN
cord-032504-tmohg1mj	77	26	a	a	DT
cord-032504-tmohg1mj	77	27	robust	robust	JJ
cord-032504-tmohg1mj	77	28	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	77	29	response	response	NN
cord-032504-tmohg1mj	77	30	with	with	IN
cord-032504-tmohg1mj	77	31	fever	fever	NN
cord-032504-tmohg1mj	77	32	and	and	CC
cord-032504-tmohg1mj	77	33	elevated	elevate	VBN
cord-032504-tmohg1mj	77	34	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	77	35	markers	marker	NNS
cord-032504-tmohg1mj	77	36	.	.	.
cord-032504-tmohg1mj	78	1	Since	since	IN
cord-032504-tmohg1mj	78	2	those	those	DT
cord-032504-tmohg1mj	78	3	landmark	landmark	NN
cord-032504-tmohg1mj	78	4	studies	study	NNS
cord-032504-tmohg1mj	78	5	,	,	,
cord-032504-tmohg1mj	78	6	much	much	JJ
cord-032504-tmohg1mj	78	7	of	of	IN
cord-032504-tmohg1mj	78	8	our	-PRON-	PRP$
cord-032504-tmohg1mj	78	9	understanding	understanding	NN
cord-032504-tmohg1mj	78	10	of	of	IN
cord-032504-tmohg1mj	78	11	these	these	DT
cord-032504-tmohg1mj	78	12	early	early	JJ
cord-032504-tmohg1mj	78	13	events	event	NNS
cord-032504-tmohg1mj	78	14	has	have	VBZ
cord-032504-tmohg1mj	78	15	relied	rely	VBN
cord-032504-tmohg1mj	78	16	on	on	IN
cord-032504-tmohg1mj	78	17	data	datum	NNS
cord-032504-tmohg1mj	78	18	from	from	IN
cord-032504-tmohg1mj	78	19	animal	animal	NN
cord-032504-tmohg1mj	78	20	models	model	NNS
cord-032504-tmohg1mj	78	21	.	.	.
cord-032504-tmohg1mj	79	1	Experiments	experiment	NNS
cord-032504-tmohg1mj	79	2	in	in	IN
cord-032504-tmohg1mj	79	3	rabbits	rabbit	NNS
cord-032504-tmohg1mj	79	4	and	and	CC
cord-032504-tmohg1mj	79	5	guinea	guinea	NN
cord-032504-tmohg1mj	79	6	pigs	pig	NNS
cord-032504-tmohg1mj	79	7	by	by	IN
cord-032504-tmohg1mj	79	8	Lurie	Lurie	NNP
cord-032504-tmohg1mj	79	9	,	,	,
cord-032504-tmohg1mj	79	10	Smith	Smith	NNP
cord-032504-tmohg1mj	79	11	,	,	,
cord-032504-tmohg1mj	79	12	and	and	CC
cord-032504-tmohg1mj	79	13	Harding	Harding	NNP
cord-032504-tmohg1mj	79	14	,	,	,
cord-032504-tmohg1mj	79	15	established	establish	VBD
cord-032504-tmohg1mj	79	16	that	that	IN
cord-032504-tmohg1mj	79	17	macrophages	macrophage	NNS
cord-032504-tmohg1mj	79	18	provide	provide	VB
cord-032504-tmohg1mj	79	19	a	a	DT
cord-032504-tmohg1mj	79	20	niche	niche	NN
cord-032504-tmohg1mj	79	21	within	within	IN
cord-032504-tmohg1mj	79	22	which	which	WDT
cord-032504-tmohg1mj	79	23	Mtb	Mtb	NNP
cord-032504-tmohg1mj	79	24	multiplies	multiply	VBZ
cord-032504-tmohg1mj	79	25	logarithmically	logarithmically	RB
cord-032504-tmohg1mj	79	26	during	during	IN
cord-032504-tmohg1mj	79	27	early	early	JJ
cord-032504-tmohg1mj	79	28	infection	infection	NN
cord-032504-tmohg1mj	79	29	[	[	-LRB-
cord-032504-tmohg1mj	79	30	44	44	CD
cord-032504-tmohg1mj	79	31	,	,	,
cord-032504-tmohg1mj	79	32	45	45	CD
cord-032504-tmohg1mj	79	33	]	]	-RRB-
cord-032504-tmohg1mj	79	34	.	.	.
cord-032504-tmohg1mj	80	1	Others	other	NNS
cord-032504-tmohg1mj	80	2	have	have	VBP
cord-032504-tmohg1mj	80	3	demonstrated	demonstrate	VBN
cord-032504-tmohg1mj	80	4	that	that	IN
cord-032504-tmohg1mj	80	5	the	the	DT
cord-032504-tmohg1mj	80	6	onset	onset	NN
cord-032504-tmohg1mj	80	7	of	of	IN
cord-032504-tmohg1mj	80	8	adaptive	adaptive	JJ
cord-032504-tmohg1mj	80	9	immunity	immunity	NN
cord-032504-tmohg1mj	80	10	in	in	IN
cord-032504-tmohg1mj	80	11	response	response	NN
cord-032504-tmohg1mj	80	12	to	to	IN
cord-032504-tmohg1mj	80	13	Mtb	Mtb	NNP
cord-032504-tmohg1mj	80	14	is	be	VBZ
cord-032504-tmohg1mj	80	15	indeed	indeed	RB
cord-032504-tmohg1mj	80	16	delayed	delay	VBN
cord-032504-tmohg1mj	80	17	,	,	,
cord-032504-tmohg1mj	80	18	arising	arise	VBG
cord-032504-tmohg1mj	80	19	in	in	IN
cord-032504-tmohg1mj	80	20	part	part	NN
cord-032504-tmohg1mj	80	21	from	from	IN
cord-032504-tmohg1mj	80	22	delayed	delayed	JJ
cord-032504-tmohg1mj	80	23	activation	activation	NN
cord-032504-tmohg1mj	80	24	of	of	IN
cord-032504-tmohg1mj	80	25	CD4	CD4	NNP
cord-032504-tmohg1mj	80	26	+	+	CC
cord-032504-tmohg1mj	80	27	T	t	NN
cord-032504-tmohg1mj	80	28	cells	cell	NNS
cord-032504-tmohg1mj	80	29	within	within	IN
cord-032504-tmohg1mj	80	30	local	local	JJ
cord-032504-tmohg1mj	80	31	lymph	lymph	NN
cord-032504-tmohg1mj	80	32	nodes	node	NNS
cord-032504-tmohg1mj	80	33	[	[	-LRB-
cord-032504-tmohg1mj	80	34	46	46	CD
cord-032504-tmohg1mj	80	35	,	,	,
cord-032504-tmohg1mj	80	36	47	47	CD
cord-032504-tmohg1mj	80	37	]	]	-RRB-
cord-032504-tmohg1mj	80	38	.	.	.
cord-032504-tmohg1mj	81	1	This	this	DT
cord-032504-tmohg1mj	81	2	delay	delay	NN
cord-032504-tmohg1mj	81	3	of	of	IN
cord-032504-tmohg1mj	81	4	several	several	JJ
cord-032504-tmohg1mj	81	5	weeks	week	NNS
cord-032504-tmohg1mj	81	6	,	,	,
cord-032504-tmohg1mj	81	7	as	as	IN
cord-032504-tmohg1mj	81	8	compared	compare	VBN
cord-032504-tmohg1mj	81	9	to	to	IN
cord-032504-tmohg1mj	81	10	several	several	JJ
cord-032504-tmohg1mj	81	11	days	day	NNS
cord-032504-tmohg1mj	81	12	with	with	IN
cord-032504-tmohg1mj	81	13	organisms	organism	NNS
cord-032504-tmohg1mj	81	14	such	such	JJ
cord-032504-tmohg1mj	81	15	as	as	IN
cord-032504-tmohg1mj	81	16	Salmonella	Salmonella	NNP
cord-032504-tmohg1mj	81	17	typhi	typhi	NNP
cord-032504-tmohg1mj	81	18	and	and	CC
cord-032504-tmohg1mj	81	19	Listeria	Listeria	NNP
cord-032504-tmohg1mj	81	20	monocytogenes	monocytogenes	NNP
cord-032504-tmohg1mj	81	21	,	,	,
cord-032504-tmohg1mj	81	22	translates	translate	VBZ
cord-032504-tmohg1mj	81	23	into	into	IN
cord-032504-tmohg1mj	81	24	relatively	relatively	RB
cord-032504-tmohg1mj	81	25	unchecked	unchecked	JJ
cord-032504-tmohg1mj	81	26	bacterial	bacterial	JJ
cord-032504-tmohg1mj	81	27	growth	growth	NN
cord-032504-tmohg1mj	81	28	during	during	IN
cord-032504-tmohg1mj	81	29	the	the	DT
cord-032504-tmohg1mj	81	30	early	early	JJ
cord-032504-tmohg1mj	81	31	phase	phase	NN
cord-032504-tmohg1mj	81	32	of	of	IN
cord-032504-tmohg1mj	81	33	infection	infection	NN
cord-032504-tmohg1mj	81	34	[	[	-LRB-
cord-032504-tmohg1mj	81	35	48	48	CD
cord-032504-tmohg1mj	81	36	,	,	,
cord-032504-tmohg1mj	81	37	49	49	CD
cord-032504-tmohg1mj	81	38	]	]	-RRB-
cord-032504-tmohg1mj	81	39	.	.	.
cord-032504-tmohg1mj	82	1	After	after	IN
cord-032504-tmohg1mj	82	2	this	this	DT
cord-032504-tmohg1mj	82	3	period	period	NN
cord-032504-tmohg1mj	82	4	of	of	IN
cord-032504-tmohg1mj	82	5	logarithmic	logarithmic	JJ
cord-032504-tmohg1mj	82	6	growth	growth	NN
cord-032504-tmohg1mj	82	7	,	,	,
cord-032504-tmohg1mj	82	8	which	which	WDT
cord-032504-tmohg1mj	82	9	has	have	VBZ
cord-032504-tmohg1mj	82	10	been	be	VBN
cord-032504-tmohg1mj	82	11	demonstrated	demonstrate	VBN
cord-032504-tmohg1mj	82	12	in	in	IN
cord-032504-tmohg1mj	82	13	rabbits	rabbit	NNS
cord-032504-tmohg1mj	82	14	,	,	,
cord-032504-tmohg1mj	82	15	mice	mouse	NNS
cord-032504-tmohg1mj	82	16	,	,	,
cord-032504-tmohg1mj	82	17	and	and	CC
cord-032504-tmohg1mj	82	18	guinea	guinea	NN
cord-032504-tmohg1mj	82	19	pigs	pig	NNS
cord-032504-tmohg1mj	82	20	,	,	,
cord-032504-tmohg1mj	82	21	the	the	DT
cord-032504-tmohg1mj	82	22	bacteria	bacteria	NNS
cord-032504-tmohg1mj	82	23	enter	enter	VBP
cord-032504-tmohg1mj	82	24	a	a	DT
cord-032504-tmohg1mj	82	25	relatively	relatively	RB
cord-032504-tmohg1mj	82	26	stationary	stationary	JJ
cord-032504-tmohg1mj	82	27	phase	phase	NN
cord-032504-tmohg1mj	82	28	[	[	-LRB-
cord-032504-tmohg1mj	82	29	50	50	CD
cord-032504-tmohg1mj	82	30	]	]	-RRB-
cord-032504-tmohg1mj	82	31	.	.	.
cord-032504-tmohg1mj	83	1	During	during	IN
cord-032504-tmohg1mj	83	2	this	this	DT
cord-032504-tmohg1mj	83	3	critical	critical	JJ
cord-032504-tmohg1mj	83	4	time	time	NN
cord-032504-tmohg1mj	83	5	,	,	,
cord-032504-tmohg1mj	83	6	Mtb	Mtb	NNP
cord-032504-tmohg1mj	83	7	subverts	subvert	VBZ
cord-032504-tmohg1mj	83	8	alveolar	alveolar	JJ
cord-032504-tmohg1mj	83	9	macrophage	macrophage	NN
cord-032504-tmohg1mj	83	10	defenses	defense	NNS
cord-032504-tmohg1mj	83	11	,	,	,
cord-032504-tmohg1mj	83	12	thereby	thereby	RB
cord-032504-tmohg1mj	83	13	ensuring	ensure	VBG
cord-032504-tmohg1mj	83	14	prolonged	prolong	VBN
cord-032504-tmohg1mj	83	15	intracellular	intracellular	JJ
cord-032504-tmohg1mj	83	16	survival	survival	NN
cord-032504-tmohg1mj	83	17	and	and	CC
cord-032504-tmohg1mj	83	18	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	83	19	growth	growth	NN
cord-032504-tmohg1mj	83	20	within	within	IN
cord-032504-tmohg1mj	83	21	this	this	DT
cord-032504-tmohg1mj	83	22	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	83	23	niche	niche	NN
cord-032504-tmohg1mj	83	24	.	.	.
cord-032504-tmohg1mj	84	1	Whether	whether	IN
cord-032504-tmohg1mj	84	2	this	this	DT
cord-032504-tmohg1mj	84	3	failure	failure	NN
cord-032504-tmohg1mj	84	4	of	of	IN
cord-032504-tmohg1mj	84	5	immunity	immunity	NN
cord-032504-tmohg1mj	84	6	represents	represent	VBZ
cord-032504-tmohg1mj	84	7	an	an	DT
cord-032504-tmohg1mj	84	8	intrinsic	intrinsic	JJ
cord-032504-tmohg1mj	84	9	deficiency	deficiency	NN
cord-032504-tmohg1mj	84	10	of	of	IN
cord-032504-tmohg1mj	84	11	macrophages	macrophage	NNS
cord-032504-tmohg1mj	84	12	or	or	CC
cord-032504-tmohg1mj	84	13	an	an	DT
cord-032504-tmohg1mj	84	14	insufficient	insufficient	JJ
cord-032504-tmohg1mj	84	15	activation	activation	NN
cord-032504-tmohg1mj	84	16	of	of	IN
cord-032504-tmohg1mj	84	17	macrophages	macrophage	NNS
cord-032504-tmohg1mj	84	18	by	by	IN
cord-032504-tmohg1mj	84	19	T	T	NNP
cord-032504-tmohg1mj	84	20	cells	cell	NNS
cord-032504-tmohg1mj	84	21	remains	remain	VBZ
cord-032504-tmohg1mj	84	22	uncertain	uncertain	JJ
cord-032504-tmohg1mj	84	23	[	[	-LRB-
cord-032504-tmohg1mj	84	24	51	51	CD
cord-032504-tmohg1mj	84	25	]	]	-RRB-
cord-032504-tmohg1mj	84	26	.	.	.
cord-032504-tmohg1mj	85	1	As	as	IN
cord-032504-tmohg1mj	85	2	discussed	discuss	VBN
cord-032504-tmohg1mj	85	3	above	above	RB
cord-032504-tmohg1mj	85	4	,	,	,
cord-032504-tmohg1mj	85	5	there	there	EX
cord-032504-tmohg1mj	85	6	has	have	VBZ
cord-032504-tmohg1mj	85	7	been	be	VBN
cord-032504-tmohg1mj	85	8	a	a	DT
cord-032504-tmohg1mj	85	9	proliferation	proliferation	NN
cord-032504-tmohg1mj	85	10	of	of	IN
cord-032504-tmohg1mj	85	11	work	work	NN
cord-032504-tmohg1mj	85	12	with	with	IN
cord-032504-tmohg1mj	85	13	non	non	JJ
cord-032504-tmohg1mj	85	14	-	-	JJ
cord-032504-tmohg1mj	85	15	human	human	JJ
cord-032504-tmohg1mj	85	16	primate	primate	JJ
cord-032504-tmohg1mj	85	17	models	model	NNS
cord-032504-tmohg1mj	85	18	in	in	IN
cord-032504-tmohg1mj	85	19	recent	recent	JJ
cord-032504-tmohg1mj	85	20	years	year	NNS
cord-032504-tmohg1mj	85	21	that	that	WDT
cord-032504-tmohg1mj	85	22	shed	shed	VBP
cord-032504-tmohg1mj	85	23	further	further	JJ
cord-032504-tmohg1mj	85	24	light	light	NN
cord-032504-tmohg1mj	85	25	on	on	IN
cord-032504-tmohg1mj	85	26	the	the	DT
cord-032504-tmohg1mj	85	27	establishment	establishment	NN
cord-032504-tmohg1mj	85	28	of	of	IN
cord-032504-tmohg1mj	85	29	the	the	DT
cord-032504-tmohg1mj	85	30	set	set	NN
cord-032504-tmohg1mj	85	31	point	point	NN
cord-032504-tmohg1mj	85	32	,	,	,
cord-032504-tmohg1mj	85	33	particularly	particularly	RB
cord-032504-tmohg1mj	85	34	with	with	IN
cord-032504-tmohg1mj	85	35	regards	regard	NNS
cord-032504-tmohg1mj	85	36	to	to	IN
cord-032504-tmohg1mj	85	37	granuloma	granuloma	NN
cord-032504-tmohg1mj	85	38	formation	formation	NN
cord-032504-tmohg1mj	85	39	[	[	-LRB-
cord-032504-tmohg1mj	85	40	52	52	CD
cord-032504-tmohg1mj	85	41	]	]	-RRB-
cord-032504-tmohg1mj	85	42	.	.	.
cord-032504-tmohg1mj	86	1	Studies	study	NNS
cord-032504-tmohg1mj	86	2	of	of	IN
cord-032504-tmohg1mj	86	3	macaques	macaque	NNS
cord-032504-tmohg1mj	86	4	with	with	IN
cord-032504-tmohg1mj	86	5	aerosol	aerosol	NN
cord-032504-tmohg1mj	86	6	exposure	exposure	NN
cord-032504-tmohg1mj	86	7	to	to	IN
cord-032504-tmohg1mj	86	8	Mtb	Mtb	NNP
cord-032504-tmohg1mj	86	9	have	have	VBP
cord-032504-tmohg1mj	86	10	found	find	VBN
cord-032504-tmohg1mj	86	11	that	that	IN
cord-032504-tmohg1mj	86	12	early	early	JJ
cord-032504-tmohg1mj	86	13	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	86	14	dissemination	dissemination	NN
cord-032504-tmohg1mj	86	15	,	,	,
cord-032504-tmohg1mj	86	16	as	as	IN
cord-032504-tmohg1mj	86	17	reflected	reflect	VBN
cord-032504-tmohg1mj	86	18	by	by	IN
cord-032504-tmohg1mj	86	19	the	the	DT
cord-032504-tmohg1mj	86	20	development	development	NN
cord-032504-tmohg1mj	86	21	of	of	IN
cord-032504-tmohg1mj	86	22	new	new	JJ
cord-032504-tmohg1mj	86	23	granulomas	granuloma	NNS
cord-032504-tmohg1mj	86	24	in	in	IN
cord-032504-tmohg1mj	86	25	the	the	DT
cord-032504-tmohg1mj	86	26	first	first	JJ
cord-032504-tmohg1mj	86	27	3	3	CD
cord-032504-tmohg1mj	86	28	-	-	SYM
cord-032504-tmohg1mj	86	29	6	6	CD
cord-032504-tmohg1mj	86	30	weeks	week	NNS
cord-032504-tmohg1mj	86	31	following	follow	VBG
cord-032504-tmohg1mj	86	32	infection	infection	NN
cord-032504-tmohg1mj	86	33	(	(	-LRB-
cord-032504-tmohg1mj	86	34	i.e.	i.e.	FW
cord-032504-tmohg1mj	86	35	,	,	,
cord-032504-tmohg1mj	86	36	the	the	DT
cord-032504-tmohg1mj	86	37	period	period	NN
cord-032504-tmohg1mj	86	38	during	during	IN
cord-032504-tmohg1mj	86	39	which	which	WDT
cord-032504-tmohg1mj	86	40	the	the	DT
cord-032504-tmohg1mj	86	41	set	set	NN
cord-032504-tmohg1mj	86	42	point	point	NN
cord-032504-tmohg1mj	86	43	is	be	VBZ
cord-032504-tmohg1mj	86	44	established	establish	VBN
cord-032504-tmohg1mj	86	45	)	)	-RRB-
cord-032504-tmohg1mj	86	46	,	,	,
cord-032504-tmohg1mj	86	47	is	be	VBZ
cord-032504-tmohg1mj	86	48	associated	associate	VBN
cord-032504-tmohg1mj	86	49	with	with	IN
cord-032504-tmohg1mj	86	50	subsequent	subsequent	JJ
cord-032504-tmohg1mj	86	51	progression	progression	NN
cord-032504-tmohg1mj	86	52	to	to	IN
cord-032504-tmohg1mj	86	53	active	active	JJ
cord-032504-tmohg1mj	86	54	disease	disease	NN
cord-032504-tmohg1mj	86	55	[	[	-LRB-
cord-032504-tmohg1mj	86	56	53	53	CD
cord-032504-tmohg1mj	86	57	,	,	,
cord-032504-tmohg1mj	86	58	54	54	CD
cord-032504-tmohg1mj	86	59	]	]	-RRB-
cord-032504-tmohg1mj	86	60	.	.	.
cord-032504-tmohg1mj	87	1	Conversely	conversely	RB
cord-032504-tmohg1mj	87	2	,	,	,
cord-032504-tmohg1mj	87	3	the	the	DT
cord-032504-tmohg1mj	87	4	absence	absence	NN
cord-032504-tmohg1mj	87	5	of	of	IN
cord-032504-tmohg1mj	87	6	new	new	JJ
cord-032504-tmohg1mj	87	7	granuloma	granuloma	NN
cord-032504-tmohg1mj	87	8	formation	formation	NN
cord-032504-tmohg1mj	87	9	,	,	,
cord-032504-tmohg1mj	87	10	which	which	WDT
cord-032504-tmohg1mj	87	11	could	could	MD
cord-032504-tmohg1mj	87	12	be	be	VB
cord-032504-tmohg1mj	87	13	construed	construe	VBN
cord-032504-tmohg1mj	87	14	as	as	IN
cord-032504-tmohg1mj	87	15	a	a	DT
cord-032504-tmohg1mj	87	16	"	"	``
cord-032504-tmohg1mj	87	17	low	low	JJ
cord-032504-tmohg1mj	87	18	"	"	''
cord-032504-tmohg1mj	87	19	set	set	NN
cord-032504-tmohg1mj	87	20	point	point	NN
cord-032504-tmohg1mj	87	21	,	,	,
cord-032504-tmohg1mj	87	22	is	be	VBZ
cord-032504-tmohg1mj	87	23	associated	associate	VBN
cord-032504-tmohg1mj	87	24	with	with	IN
cord-032504-tmohg1mj	87	25	immune	immune	JJ
cord-032504-tmohg1mj	87	26	control	control	NN
cord-032504-tmohg1mj	87	27	and	and	CC
cord-032504-tmohg1mj	87	28	long	long	JJ
cord-032504-tmohg1mj	87	29	-	-	HYPH
cord-032504-tmohg1mj	87	30	term	term	NN
cord-032504-tmohg1mj	87	31	maintenance	maintenance	NN
cord-032504-tmohg1mj	87	32	of	of	IN
cord-032504-tmohg1mj	87	33	latent	latent	JJ
cord-032504-tmohg1mj	87	34	infection	infection	NN
cord-032504-tmohg1mj	87	35	.	.	.
cord-032504-tmohg1mj	88	1	Granuloma	Granuloma	NNP
cord-032504-tmohg1mj	88	2	size	size	NN
cord-032504-tmohg1mj	88	3	can	can	MD
cord-032504-tmohg1mj	88	4	also	also	RB
cord-032504-tmohg1mj	88	5	stratify	stratify	VB
cord-032504-tmohg1mj	88	6	the	the	DT
cord-032504-tmohg1mj	88	7	risk	risk	NN
cord-032504-tmohg1mj	88	8	of	of	IN
cord-032504-tmohg1mj	88	9	dissemination	dissemination	NN
cord-032504-tmohg1mj	88	10	,	,	,
cord-032504-tmohg1mj	88	11	with	with	IN
cord-032504-tmohg1mj	88	12	larger	large	JJR
cord-032504-tmohg1mj	88	13	granulomas	granuloma	NNS
cord-032504-tmohg1mj	88	14	associated	associate	VBN
cord-032504-tmohg1mj	88	15	with	with	IN
cord-032504-tmohg1mj	88	16	a	a	DT
cord-032504-tmohg1mj	88	17	greater	great	JJR
cord-032504-tmohg1mj	88	18	potential	potential	NN
cord-032504-tmohg1mj	88	19	for	for	IN
cord-032504-tmohg1mj	88	20	future	future	JJ
cord-032504-tmohg1mj	88	21	mycobacterial	mycobacterial	NN
cord-032504-tmohg1mj	88	22	spread	spread	VBD
cord-032504-tmohg1mj	88	23	[	[	-LRB-
cord-032504-tmohg1mj	88	24	55	55	CD
cord-032504-tmohg1mj	88	25	]	]	-RRB-
cord-032504-tmohg1mj	88	26	.	.	.
cord-032504-tmohg1mj	89	1	By	by	IN
cord-032504-tmohg1mj	89	2	linking	link	VBG
cord-032504-tmohg1mj	89	3	early	early	JJ
cord-032504-tmohg1mj	89	4	immunologic	immunologic	JJ
cord-032504-tmohg1mj	89	5	events	event	NNS
cord-032504-tmohg1mj	89	6	to	to	IN
cord-032504-tmohg1mj	89	7	clinically	clinically	RB
cord-032504-tmohg1mj	89	8	meaningful	meaningful	JJ
cord-032504-tmohg1mj	89	9	outcomes	outcome	NNS
cord-032504-tmohg1mj	89	10	,	,	,
cord-032504-tmohg1mj	89	11	these	these	DT
cord-032504-tmohg1mj	89	12	findings	finding	NNS
cord-032504-tmohg1mj	89	13	underscore	underscore	VBP
cord-032504-tmohg1mj	89	14	the	the	DT
cord-032504-tmohg1mj	89	15	critical	critical	JJ
cord-032504-tmohg1mj	89	16	importance	importance	NN
cord-032504-tmohg1mj	89	17	of	of	IN
cord-032504-tmohg1mj	89	18	early	early	JJ
cord-032504-tmohg1mj	89	19	immune	immune	JJ
cord-032504-tmohg1mj	89	20	control	control	NN
cord-032504-tmohg1mj	89	21	prior	prior	RB
cord-032504-tmohg1mj	89	22	to	to	IN
cord-032504-tmohg1mj	89	23	the	the	DT
cord-032504-tmohg1mj	89	24	onset	onset	NN
cord-032504-tmohg1mj	89	25	of	of	IN
cord-032504-tmohg1mj	89	26	adaptive	adaptive	JJ
cord-032504-tmohg1mj	89	27	immunity	immunity	NN
cord-032504-tmohg1mj	89	28	.	.	.
cord-032504-tmohg1mj	90	1	They	-PRON-	PRP
cord-032504-tmohg1mj	90	2	also	also	RB
cord-032504-tmohg1mj	90	3	provide	provide	VBP
cord-032504-tmohg1mj	90	4	evidence	evidence	NN
cord-032504-tmohg1mj	90	5	to	to	TO
cord-032504-tmohg1mj	90	6	support	support	VB
cord-032504-tmohg1mj	90	7	the	the	DT
cord-032504-tmohg1mj	90	8	longstanding	longstanding	JJ
cord-032504-tmohg1mj	90	9	belief	belief	NN
cord-032504-tmohg1mj	90	10	that	that	IN
cord-032504-tmohg1mj	90	11	progression	progression	NN
cord-032504-tmohg1mj	90	12	to	to	IN
cord-032504-tmohg1mj	90	13	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	90	14	disease	disease	NN
cord-032504-tmohg1mj	90	15	is	be	VBZ
cord-032504-tmohg1mj	90	16	determined	determine	VBN
cord-032504-tmohg1mj	90	17	at	at	IN
cord-032504-tmohg1mj	90	18	the	the	DT
cord-032504-tmohg1mj	90	19	level	level	NN
cord-032504-tmohg1mj	90	20	of	of	IN
cord-032504-tmohg1mj	90	21	the	the	DT
cord-032504-tmohg1mj	90	22	individual	individual	JJ
cord-032504-tmohg1mj	90	23	granuloma	granuloma	NN
cord-032504-tmohg1mj	90	24	.	.	.
cord-032504-tmohg1mj	91	1	As	as	IN
cord-032504-tmohg1mj	91	2	the	the	DT
cord-032504-tmohg1mj	91	3	first	first	JJ
cord-032504-tmohg1mj	91	4	cell	cell	NN
cord-032504-tmohg1mj	91	5	type	type	NN
cord-032504-tmohg1mj	91	6	to	to	TO
cord-032504-tmohg1mj	91	7	encounter	encounter	VB
cord-032504-tmohg1mj	91	8	Mtb	Mtb	NNP
cord-032504-tmohg1mj	91	9	,	,	,
cord-032504-tmohg1mj	91	10	the	the	DT
cord-032504-tmohg1mj	91	11	alveolar	alveolar	JJ
cord-032504-tmohg1mj	91	12	macrophage	macrophage	NN
cord-032504-tmohg1mj	91	13	is	be	VBZ
cord-032504-tmohg1mj	91	14	a	a	DT
cord-032504-tmohg1mj	91	15	key	key	JJ
cord-032504-tmohg1mj	91	16	player	player	NN
cord-032504-tmohg1mj	91	17	in	in	IN
cord-032504-tmohg1mj	91	18	the	the	DT
cord-032504-tmohg1mj	91	19	early	early	JJ
cord-032504-tmohg1mj	91	20	stages	stage	NNS
cord-032504-tmohg1mj	91	21	of	of	IN
cord-032504-tmohg1mj	91	22	infection	infection	NN
cord-032504-tmohg1mj	91	23	and	and	CC
cord-032504-tmohg1mj	91	24	Mtb	Mtb	NNP
cord-032504-tmohg1mj	91	25	is	be	VBZ
cord-032504-tmohg1mj	91	26	known	know	VBN
cord-032504-tmohg1mj	91	27	to	to	IN
cord-032504-tmohg1mj	91	28	both	both	DT
cord-032504-tmohg1mj	91	29	cause	cause	VB
cord-032504-tmohg1mj	91	30	and	and	CC
cord-032504-tmohg1mj	91	31	benefit	benefit	VBP
cord-032504-tmohg1mj	91	32	from	from	IN
cord-032504-tmohg1mj	91	33	certain	certain	JJ
cord-032504-tmohg1mj	91	34	alterations	alteration	NNS
cord-032504-tmohg1mj	91	35	in	in	IN
cord-032504-tmohg1mj	91	36	macrophage	macrophage	NN
cord-032504-tmohg1mj	91	37	functionality	functionality	NN
cord-032504-tmohg1mj	91	38	[	[	-LRB-
cord-032504-tmohg1mj	91	39	56	56	CD
cord-032504-tmohg1mj	91	40	]	]	-RRB-
cord-032504-tmohg1mj	91	41	.	.	.
cord-032504-tmohg1mj	92	1	Several	several	JJ
cord-032504-tmohg1mj	92	2	excellent	excellent	JJ
cord-032504-tmohg1mj	92	3	reviews	review	NNS
cord-032504-tmohg1mj	92	4	have	have	VBP
cord-032504-tmohg1mj	92	5	recently	recently	RB
cord-032504-tmohg1mj	92	6	examined	examine	VBN
cord-032504-tmohg1mj	92	7	the	the	DT
cord-032504-tmohg1mj	92	8	heterogeneity	heterogeneity	NN
cord-032504-tmohg1mj	92	9	and	and	CC
cord-032504-tmohg1mj	92	10	plasticity	plasticity	NN
cord-032504-tmohg1mj	92	11	of	of	IN
cord-032504-tmohg1mj	92	12	macrophages	macrophage	NNS
cord-032504-tmohg1mj	92	13	,	,	,
cord-032504-tmohg1mj	92	14	in	in	IN
cord-032504-tmohg1mj	92	15	addition	addition	NN
cord-032504-tmohg1mj	92	16	to	to	IN
cord-032504-tmohg1mj	92	17	proposing	propose	VBG
cord-032504-tmohg1mj	92	18	a	a	DT
cord-032504-tmohg1mj	92	19	uniform	uniform	JJ
cord-032504-tmohg1mj	92	20	approach	approach	NN
cord-032504-tmohg1mj	92	21	to	to	IN
cord-032504-tmohg1mj	92	22	macrophage	macrophage	NN
cord-032504-tmohg1mj	92	23	nomenclature	nomenclature	NN
cord-032504-tmohg1mj	92	24	[	[	-LRB-
cord-032504-tmohg1mj	92	25	31	31	CD
cord-032504-tmohg1mj	92	26	,	,	,
cord-032504-tmohg1mj	92	27	32	32	CD
cord-032504-tmohg1mj	92	28	]	]	-RRB-
cord-032504-tmohg1mj	92	29	.	.	.
cord-032504-tmohg1mj	93	1	Alveolar	alveolar	NN
cord-032504-tmohg1mj	93	2	macrophages	macrophage	NNS
cord-032504-tmohg1mj	93	3	play	play	VBP
cord-032504-tmohg1mj	93	4	myriad	myriad	JJ
cord-032504-tmohg1mj	93	5	roles	role	NNS
cord-032504-tmohg1mj	93	6	in	in	IN
cord-032504-tmohg1mj	93	7	the	the	DT
cord-032504-tmohg1mj	93	8	lungs	lung	NNS
cord-032504-tmohg1mj	93	9	,	,	,
cord-032504-tmohg1mj	93	10	from	from	IN
cord-032504-tmohg1mj	93	11	housekeeper	housekeeper	NN
cord-032504-tmohg1mj	93	12	to	to	TO
cord-032504-tmohg1mj	93	13	innate	innate	VB
cord-032504-tmohg1mj	93	14	immune	immune	JJ
cord-032504-tmohg1mj	93	15	effector	effector	NN
cord-032504-tmohg1mj	93	16	,	,	,
cord-032504-tmohg1mj	93	17	and	and	CC
cord-032504-tmohg1mj	93	18	their	-PRON-	PRP$
cord-032504-tmohg1mj	93	19	role	role	NN
cord-032504-tmohg1mj	93	20	depends	depend	VBZ
cord-032504-tmohg1mj	93	21	heavily	heavily	RB
cord-032504-tmohg1mj	93	22	on	on	IN
cord-032504-tmohg1mj	93	23	the	the	DT
cord-032504-tmohg1mj	93	24	microenvironment	microenvironment	NN
cord-032504-tmohg1mj	93	25	within	within	IN
cord-032504-tmohg1mj	93	26	the	the	DT
cord-032504-tmohg1mj	93	27	alveolar	alveolar	JJ
cord-032504-tmohg1mj	93	28	space	space	NN
cord-032504-tmohg1mj	93	29	.	.	.
cord-032504-tmohg1mj	94	1	For	for	IN
cord-032504-tmohg1mj	94	2	example	example	NN
cord-032504-tmohg1mj	94	3	,	,	,
cord-032504-tmohg1mj	94	4	in	in	IN
cord-032504-tmohg1mj	94	5	response	response	NN
cord-032504-tmohg1mj	94	6	to	to	IN
cord-032504-tmohg1mj	94	7	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	94	8	stimuli	stimulus	NNS
cord-032504-tmohg1mj	94	9	such	such	JJ
cord-032504-tmohg1mj	94	10	as	as	IN
cord-032504-tmohg1mj	94	11	lipopolysaccharide	lipopolysaccharide	NN
cord-032504-tmohg1mj	94	12	(	(	-LRB-
cord-032504-tmohg1mj	94	13	LPS	LPS	NNP
cord-032504-tmohg1mj	94	14	)	)	-RRB-
cord-032504-tmohg1mj	94	15	,	,	,
cord-032504-tmohg1mj	94	16	alveolar	alveolar	NN
cord-032504-tmohg1mj	94	17	macrophages	macrophage	NNS
cord-032504-tmohg1mj	94	18	develop	develop	VBP
cord-032504-tmohg1mj	94	19	an	an	DT
cord-032504-tmohg1mj	94	20	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	94	21	phenotype	phenotype	NN
cord-032504-tmohg1mj	94	22	with	with	IN
cord-032504-tmohg1mj	94	23	increased	increase	VBN
cord-032504-tmohg1mj	94	24	production	production	NN
cord-032504-tmohg1mj	94	25	of	of	IN
cord-032504-tmohg1mj	94	26	cytokines	cytokine	NNS
cord-032504-tmohg1mj	94	27	such	such	JJ
cord-032504-tmohg1mj	94	28	as	as	IN
cord-032504-tmohg1mj	94	29	TNF	TNF	NNP
cord-032504-tmohg1mj	94	30	-	-	HYPH
cord-032504-tmohg1mj	94	31	α	α	NNP
cord-032504-tmohg1mj	94	32	and	and	CC
cord-032504-tmohg1mj	94	33	IL-6	IL-6	NNP
cord-032504-tmohg1mj	94	34	.	.	.
cord-032504-tmohg1mj	95	1	Conversely	conversely	RB
cord-032504-tmohg1mj	95	2	,	,	,
cord-032504-tmohg1mj	95	3	in	in	IN
cord-032504-tmohg1mj	95	4	the	the	DT
cord-032504-tmohg1mj	95	5	setting	setting	NN
cord-032504-tmohg1mj	95	6	of	of	IN
cord-032504-tmohg1mj	95	7	IL-4	IL-4	NNP
cord-032504-tmohg1mj	95	8	exposure	exposure	NN
cord-032504-tmohg1mj	95	9	,	,	,
cord-032504-tmohg1mj	95	10	alveolar	alveolar	NN
cord-032504-tmohg1mj	95	11	macrophages	macrophage	NNS
cord-032504-tmohg1mj	95	12	shift	shift	VBP
cord-032504-tmohg1mj	95	13	to	to	IN
cord-032504-tmohg1mj	95	14	an	an	DT
cord-032504-tmohg1mj	95	15	immunosuppressive	immunosuppressive	JJ
cord-032504-tmohg1mj	95	16	phenotype	phenotype	NN
cord-032504-tmohg1mj	95	17	and	and	CC
cord-032504-tmohg1mj	95	18	increase	increase	VB
cord-032504-tmohg1mj	95	19	production	production	NN
cord-032504-tmohg1mj	95	20	of	of	IN
cord-032504-tmohg1mj	95	21	regulatory	regulatory	JJ
cord-032504-tmohg1mj	95	22	cytokines	cytokine	NNS
cord-032504-tmohg1mj	95	23	such	such	JJ
cord-032504-tmohg1mj	95	24	as	as	IN
cord-032504-tmohg1mj	95	25	TGF	TGF	NNP
cord-032504-tmohg1mj	95	26	-	-	HYPH
cord-032504-tmohg1mj	95	27	β	β	NNP
cord-032504-tmohg1mj	95	28	[	[	-LRB-
cord-032504-tmohg1mj	95	29	31	31	CD
cord-032504-tmohg1mj	95	30	]	]	-RRB-
cord-032504-tmohg1mj	95	31	.	.	.
cord-032504-tmohg1mj	96	1	Although	although	IN
cord-032504-tmohg1mj	96	2	debate	debate	NN
cord-032504-tmohg1mj	96	3	continues	continue	VBZ
cord-032504-tmohg1mj	96	4	as	as	IN
cord-032504-tmohg1mj	96	5	to	to	IN
cord-032504-tmohg1mj	96	6	how	how	WRB
cord-032504-tmohg1mj	96	7	best	good	JJS
cord-032504-tmohg1mj	96	8	to	to	TO
cord-032504-tmohg1mj	96	9	characterize	characterize	VB
cord-032504-tmohg1mj	96	10	macrophages	macrophage	NNS
cord-032504-tmohg1mj	96	11	and	and	CC
cord-032504-tmohg1mj	96	12	how	how	WRB
cord-032504-tmohg1mj	96	13	dynamically	dynamically	RB
cord-032504-tmohg1mj	96	14	tissue	tissue	NN
cord-032504-tmohg1mj	96	15	resident	resident	NN
cord-032504-tmohg1mj	96	16	subtypes	subtype	NNS
cord-032504-tmohg1mj	96	17	respond	respond	VBP
cord-032504-tmohg1mj	96	18	to	to	IN
cord-032504-tmohg1mj	96	19	their	-PRON-	PRP$
cord-032504-tmohg1mj	96	20	local	local	JJ
cord-032504-tmohg1mj	96	21	cytokine	cytokine	NN
cord-032504-tmohg1mj	96	22	milieu	milieu	NN
cord-032504-tmohg1mj	96	23	,	,	,
cord-032504-tmohg1mj	96	24	it	-PRON-	PRP
cord-032504-tmohg1mj	96	25	is	be	VBZ
cord-032504-tmohg1mj	96	26	well	well	RB
cord-032504-tmohg1mj	96	27	known	know	VBN
cord-032504-tmohg1mj	96	28	that	that	IN
cord-032504-tmohg1mj	96	29	macrophages	macrophage	NNS
cord-032504-tmohg1mj	96	30	respond	respond	VBP
cord-032504-tmohg1mj	96	31	to	to	IN
cord-032504-tmohg1mj	96	32	different	different	JJ
cord-032504-tmohg1mj	96	33	cytokine	cytokine	NN
cord-032504-tmohg1mj	96	34	programs	program	NNS
cord-032504-tmohg1mj	96	35	with	with	IN
cord-032504-tmohg1mj	96	36	a	a	DT
cord-032504-tmohg1mj	96	37	variety	variety	NN
cord-032504-tmohg1mj	96	38	of	of	IN
cord-032504-tmohg1mj	96	39	functional	functional	JJ
cord-032504-tmohg1mj	96	40	changes	change	NNS
cord-032504-tmohg1mj	96	41	.	.	.
cord-032504-tmohg1mj	97	1	Most	Most	JJS
cord-032504-tmohg1mj	97	2	experts	expert	NNS
cord-032504-tmohg1mj	97	3	agree	agree	VBP
cord-032504-tmohg1mj	97	4	that	that	IN
cord-032504-tmohg1mj	97	5	these	these	DT
cord-032504-tmohg1mj	97	6	changes	change	NNS
cord-032504-tmohg1mj	97	7	exist	exist	VBP
cord-032504-tmohg1mj	97	8	on	on	IN
cord-032504-tmohg1mj	97	9	a	a	DT
cord-032504-tmohg1mj	97	10	spectrum	spectrum	NN
cord-032504-tmohg1mj	97	11	between	between	IN
cord-032504-tmohg1mj	97	12	the	the	DT
cord-032504-tmohg1mj	97	13	classically	classically	RB
cord-032504-tmohg1mj	97	14	activated	activate	VBN
cord-032504-tmohg1mj	97	15	(	(	-LRB-
cord-032504-tmohg1mj	97	16	or	or	CC
cord-032504-tmohg1mj	97	17	M1	M1	NNP
cord-032504-tmohg1mj	97	18	,	,	,
cord-032504-tmohg1mj	97	19	or	or	CC
cord-032504-tmohg1mj	97	20	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	97	21	)	)	-RRB-
cord-032504-tmohg1mj	97	22	macrophage	macrophage	NN
cord-032504-tmohg1mj	97	23	and	and	CC
cord-032504-tmohg1mj	97	24	an	an	DT
cord-032504-tmohg1mj	97	25	alternatively	alternatively	RB
cord-032504-tmohg1mj	97	26	activated	activate	VBN
cord-032504-tmohg1mj	97	27	(	(	-LRB-
cord-032504-tmohg1mj	97	28	or	or	CC
cord-032504-tmohg1mj	97	29	M2	M2	NNP
cord-032504-tmohg1mj	97	30	,	,	,
cord-032504-tmohg1mj	97	31	or	or	CC
cord-032504-tmohg1mj	97	32	regulatory	regulatory	JJ
cord-032504-tmohg1mj	97	33	)	)	-RRB-
cord-032504-tmohg1mj	97	34	macrophage	macrophage	NN
cord-032504-tmohg1mj	97	35	.	.	.
cord-032504-tmohg1mj	98	1	In	in	IN
cord-032504-tmohg1mj	98	2	the	the	DT
cord-032504-tmohg1mj	98	3	context	context	NN
cord-032504-tmohg1mj	98	4	of	of	IN
cord-032504-tmohg1mj	98	5	Mtb	Mtb	NNP
cord-032504-tmohg1mj	98	6	infection	infection	NN
cord-032504-tmohg1mj	98	7	,	,	,
cord-032504-tmohg1mj	98	8	the	the	DT
cord-032504-tmohg1mj	98	9	"	"	``
cord-032504-tmohg1mj	98	10	macrophage	macrophage	NN
cord-032504-tmohg1mj	98	11	polarization	polarization	NN
cord-032504-tmohg1mj	98	12	ratio	ratio	NN
cord-032504-tmohg1mj	98	13	,	,	,
cord-032504-tmohg1mj	98	14	"	"	''
cord-032504-tmohg1mj	98	15	an	an	DT
cord-032504-tmohg1mj	98	16	indicator	indicator	NN
cord-032504-tmohg1mj	98	17	of	of	IN
cord-032504-tmohg1mj	98	18	the	the	DT
cord-032504-tmohg1mj	98	19	balance	balance	NN
cord-032504-tmohg1mj	98	20	between	between	IN
cord-032504-tmohg1mj	98	21	proinflammatory	proinflammatory	JJ
cord-032504-tmohg1mj	98	22	and	and	CC
cord-032504-tmohg1mj	98	23	anti	anti	JJ
cord-032504-tmohg1mj	98	24	-	-	JJ
cord-032504-tmohg1mj	98	25	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	98	26	genes	gene	NNS
cord-032504-tmohg1mj	98	27	,	,	,
cord-032504-tmohg1mj	98	28	has	have	VBZ
cord-032504-tmohg1mj	98	29	been	be	VBN
cord-032504-tmohg1mj	98	30	employed	employ	VBN
cord-032504-tmohg1mj	98	31	to	to	TO
cord-032504-tmohg1mj	98	32	explore	explore	VB
cord-032504-tmohg1mj	98	33	how	how	WRB
cord-032504-tmohg1mj	98	34	macrophage	macrophage	NN
cord-032504-tmohg1mj	98	35	functionality	functionality	NN
cord-032504-tmohg1mj	98	36	and	and	CC
cord-032504-tmohg1mj	98	37	subsequent	subsequent	JJ
cord-032504-tmohg1mj	98	38	granuloma	granuloma	NN
cord-032504-tmohg1mj	98	39	formation	formation	NN
cord-032504-tmohg1mj	98	40	affects	affect	VBZ
cord-032504-tmohg1mj	98	41	the	the	DT
cord-032504-tmohg1mj	98	42	probabilities	probability	NNS
cord-032504-tmohg1mj	98	43	of	of	IN
cord-032504-tmohg1mj	98	44	Mtb	Mtb	NNP
cord-032504-tmohg1mj	98	45	control	control	NN
cord-032504-tmohg1mj	98	46	and	and	CC
cord-032504-tmohg1mj	98	47	dissemination	dissemination	NN
cord-032504-tmohg1mj	98	48	(	(	-LRB-
cord-032504-tmohg1mj	98	49	Fig	Fig	NNP
cord-032504-tmohg1mj	98	50	.	.	NNP
cord-032504-tmohg1mj	98	51	2	2	LS
cord-032504-tmohg1mj	98	52	)	)	-RRB-
cord-032504-tmohg1mj	98	53	[	[	-LRB-
cord-032504-tmohg1mj	98	54	57	57	CD
cord-032504-tmohg1mj	98	55	]	]	-RRB-
cord-032504-tmohg1mj	98	56	.	.	.
cord-032504-tmohg1mj	99	1	With	with	IN
cord-032504-tmohg1mj	99	2	this	this	DT
cord-032504-tmohg1mj	99	3	approach	approach	NN
cord-032504-tmohg1mj	99	4	,	,	,
cord-032504-tmohg1mj	99	5	NF	NF	NNP
cord-032504-tmohg1mj	99	6	-	-	HYPH
cord-032504-tmohg1mj	99	7	kB	kB	NNP
cord-032504-tmohg1mj	99	8	signaling	signaling	NN
cord-032504-tmohg1mj	99	9	was	be	VBD
cord-032504-tmohg1mj	99	10	found	find	VBN
cord-032504-tmohg1mj	99	11	to	to	TO
cord-032504-tmohg1mj	99	12	be	be	VB
cord-032504-tmohg1mj	99	13	an	an	DT
cord-032504-tmohg1mj	99	14	essential	essential	JJ
cord-032504-tmohg1mj	99	15	component	component	NN
cord-032504-tmohg1mj	99	16	of	of	IN
cord-032504-tmohg1mj	99	17	the	the	DT
cord-032504-tmohg1mj	99	18	classical	classical	JJ
cord-032504-tmohg1mj	99	19	activation	activation	NN
cord-032504-tmohg1mj	99	20	profile	profile	NN
cord-032504-tmohg1mj	99	21	,	,	,
cord-032504-tmohg1mj	99	22	which	which	WDT
cord-032504-tmohg1mj	99	23	,	,	,
cord-032504-tmohg1mj	99	24	when	when	WRB
cord-032504-tmohg1mj	99	25	triggered	trigger	VBN
cord-032504-tmohg1mj	99	26	early	early	RB
cord-032504-tmohg1mj	99	27	,	,	,
cord-032504-tmohg1mj	99	28	leads	lead	VBZ
cord-032504-tmohg1mj	99	29	to	to	IN
cord-032504-tmohg1mj	99	30	improved	improve	VBN
cord-032504-tmohg1mj	99	31	clinical	clinical	JJ
cord-032504-tmohg1mj	99	32	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	99	33	outcomes	outcome	NNS
cord-032504-tmohg1mj	99	34	in	in	IN
cord-032504-tmohg1mj	99	35	a	a	DT
cord-032504-tmohg1mj	99	36	nonhuman	nonhuman	NN
cord-032504-tmohg1mj	99	37	primate	primate	NN
cord-032504-tmohg1mj	99	38	model	model	NN
cord-032504-tmohg1mj	99	39	[	[	-LRB-
cord-032504-tmohg1mj	99	40	57	57	CD
cord-032504-tmohg1mj	99	41	]	]	-RRB-
cord-032504-tmohg1mj	99	42	.	.	.
cord-032504-tmohg1mj	100	1	Alveolar	alveolar	JJ
cord-032504-tmohg1mj	100	2	macrophages	macrophage	NNS
cord-032504-tmohg1mj	100	3	are	be	VBP
cord-032504-tmohg1mj	100	4	also	also	RB
cord-032504-tmohg1mj	100	5	severely	severely	RB
cord-032504-tmohg1mj	100	6	impacted	impact	VBN
cord-032504-tmohg1mj	100	7	by	by	IN
cord-032504-tmohg1mj	100	8	the	the	DT
cord-032504-tmohg1mj	100	9	presence	presence	NN
cord-032504-tmohg1mj	100	10	of	of	IN
cord-032504-tmohg1mj	100	11	HIV	HIV	NNP
cord-032504-tmohg1mj	100	12	infection	infection	NN
cord-032504-tmohg1mj	100	13	and	and	CC
cord-032504-tmohg1mj	100	14	have	have	VBP
cord-032504-tmohg1mj	100	15	been	be	VBN
cord-032504-tmohg1mj	100	16	shown	show	VBN
cord-032504-tmohg1mj	100	17	to	to	TO
cord-032504-tmohg1mj	100	18	be	be	VB
cord-032504-tmohg1mj	100	19	a	a	DT
cord-032504-tmohg1mj	100	20	reservoir	reservoir	NN
cord-032504-tmohg1mj	100	21	for	for	IN
cord-032504-tmohg1mj	100	22	the	the	DT
cord-032504-tmohg1mj	100	23	virus	virus	NN
cord-032504-tmohg1mj	100	24	within	within	IN
cord-032504-tmohg1mj	100	25	the	the	DT
cord-032504-tmohg1mj	100	26	lungs	lung	NNS
cord-032504-tmohg1mj	100	27	[	[	-LRB-
cord-032504-tmohg1mj	100	28	58	58	CD
cord-032504-tmohg1mj	100	29	]	]	-RRB-
cord-032504-tmohg1mj	100	30	.	.	.
cord-032504-tmohg1mj	101	1	Importantly	importantly	RB
cord-032504-tmohg1mj	101	2	,	,	,
cord-032504-tmohg1mj	101	3	coinfection	coinfection	NN
cord-032504-tmohg1mj	101	4	shifts	shift	VBZ
cord-032504-tmohg1mj	101	5	macrophage	macrophage	NN
cord-032504-tmohg1mj	101	6	polarization	polarization	NN
cord-032504-tmohg1mj	101	7	in	in	IN
cord-032504-tmohg1mj	101	8	a	a	DT
cord-032504-tmohg1mj	101	9	fashion	fashion	NN
cord-032504-tmohg1mj	101	10	favorable	favorable	JJ
cord-032504-tmohg1mj	101	11	for	for	IN
cord-032504-tmohg1mj	101	12	pathogen	pathogen	NN
cord-032504-tmohg1mj	101	13	survival	survival	NN
cord-032504-tmohg1mj	101	14	[	[	-LRB-
cord-032504-tmohg1mj	101	15	59	59	CD
cord-032504-tmohg1mj	101	16	]	]	-RRB-
cord-032504-tmohg1mj	101	17	.	.	.
cord-032504-tmohg1mj	102	1	Both	both	DT
cord-032504-tmohg1mj	102	2	HIV	HIV	NNP
cord-032504-tmohg1mj	102	3	and	and	CC
cord-032504-tmohg1mj	102	4	Mtb	Mtb	NNP
cord-032504-tmohg1mj	102	5	stimulate	stimulate	VBP
cord-032504-tmohg1mj	102	6	a	a	DT
cord-032504-tmohg1mj	102	7	cytokine	cytokine	NN
cord-032504-tmohg1mj	102	8	milieu	milieu	NN
cord-032504-tmohg1mj	102	9	in	in	IN
cord-032504-tmohg1mj	102	10	the	the	DT
cord-032504-tmohg1mj	102	11	alveolar	alveolar	JJ
cord-032504-tmohg1mj	102	12	space	space	NN
cord-032504-tmohg1mj	102	13	that	that	WDT
cord-032504-tmohg1mj	102	14	pushes	push	VBZ
cord-032504-tmohg1mj	102	15	macrophages	macrophage	NNS
cord-032504-tmohg1mj	102	16	into	into	IN
cord-032504-tmohg1mj	102	17	an	an	DT
cord-032504-tmohg1mj	102	18	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	102	19	phenotype	phenotype	NN
cord-032504-tmohg1mj	102	20	optimized	optimize	VBN
cord-032504-tmohg1mj	102	21	for	for	IN
cord-032504-tmohg1mj	102	22	the	the	DT
cord-032504-tmohg1mj	102	23	uptake	uptake	NN
cord-032504-tmohg1mj	102	24	of	of	IN
cord-032504-tmohg1mj	102	25	foreign	foreign	JJ
cord-032504-tmohg1mj	102	26	microbes	microbe	NNS
cord-032504-tmohg1mj	102	27	.	.	.
cord-032504-tmohg1mj	103	1	Although	although	IN
cord-032504-tmohg1mj	103	2	these	these	DT
cord-032504-tmohg1mj	103	3	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	103	4	cells	cell	NNS
cord-032504-tmohg1mj	103	5	would	would	MD
cord-032504-tmohg1mj	103	6	ordinarily	ordinarily	RB
cord-032504-tmohg1mj	103	7	excel	excel	VB
cord-032504-tmohg1mj	103	8	at	at	IN
cord-032504-tmohg1mj	103	9	pathogen	pathogen	NN
cord-032504-tmohg1mj	103	10	killing	killing	NN
cord-032504-tmohg1mj	103	11	,	,	,
cord-032504-tmohg1mj	103	12	the	the	DT
cord-032504-tmohg1mj	103	13	intracellular	intracellular	JJ
cord-032504-tmohg1mj	103	14	effects	effect	NNS
cord-032504-tmohg1mj	103	15	of	of	IN
cord-032504-tmohg1mj	103	16	HIV	HIV	NNP
cord-032504-tmohg1mj	103	17	and	and	CC
cord-032504-tmohg1mj	103	18	Mtb	Mtb	NNP
cord-032504-tmohg1mj	103	19	render	render	VBP
cord-032504-tmohg1mj	103	20	the	the	DT
cord-032504-tmohg1mj	103	21	macrophages	macrophage	NNS
cord-032504-tmohg1mj	103	22	less	less	RBR
cord-032504-tmohg1mj	103	23	effective	effective	JJ
cord-032504-tmohg1mj	103	24	and	and	CC
cord-032504-tmohg1mj	103	25	,	,	,
cord-032504-tmohg1mj	103	26	as	as	IN
cord-032504-tmohg1mj	103	27	a	a	DT
cord-032504-tmohg1mj	103	28	result	result	NN
cord-032504-tmohg1mj	103	29	,	,	,
cord-032504-tmohg1mj	103	30	permit	permit	VB
cord-032504-tmohg1mj	103	31	ongoing	ongoing	JJ
cord-032504-tmohg1mj	103	32	pathogen	pathogen	NN
cord-032504-tmohg1mj	103	33	growth	growth	NN
cord-032504-tmohg1mj	103	34	[	[	-LRB-
cord-032504-tmohg1mj	103	35	60	60	CD
cord-032504-tmohg1mj	103	36	]	]	-RRB-
cord-032504-tmohg1mj	103	37	.	.	.
cord-032504-tmohg1mj	104	1	At	at	IN
cord-032504-tmohg1mj	104	2	the	the	DT
cord-032504-tmohg1mj	104	3	same	same	JJ
cord-032504-tmohg1mj	104	4	time	time	NN
cord-032504-tmohg1mj	104	5	,	,	,
cord-032504-tmohg1mj	104	6	there	there	EX
cord-032504-tmohg1mj	104	7	is	be	VBZ
cord-032504-tmohg1mj	104	8	ample	ample	JJ
cord-032504-tmohg1mj	104	9	evidence	evidence	NN
cord-032504-tmohg1mj	104	10	that	that	IN
cord-032504-tmohg1mj	104	11	Mtb	Mtb	NNP
cord-032504-tmohg1mj	104	12	infection	infection	NN
cord-032504-tmohg1mj	104	13	of	of	IN
cord-032504-tmohg1mj	104	14	alveolar	alveolar	JJ
cord-032504-tmohg1mj	104	15	macrophages	macrophage	NNS
cord-032504-tmohg1mj	104	16	creates	create	VBZ
cord-032504-tmohg1mj	104	17	a	a	DT
cord-032504-tmohg1mj	104	18	permissive	permissive	JJ
cord-032504-tmohg1mj	104	19	environment	environment	NN
cord-032504-tmohg1mj	104	20	for	for	IN
cord-032504-tmohg1mj	104	21	HIV	HIV	NNP
cord-032504-tmohg1mj	104	22	infection	infection	NN
cord-032504-tmohg1mj	104	23	and	and	CC
cord-032504-tmohg1mj	104	24	replication	replication	NN
cord-032504-tmohg1mj	104	25	,	,	,
cord-032504-tmohg1mj	104	26	through	through	IN
cord-032504-tmohg1mj	104	27	a	a	DT
cord-032504-tmohg1mj	104	28	variety	variety	NN
cord-032504-tmohg1mj	104	29	of	of	IN
cord-032504-tmohg1mj	104	30	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	104	31	including	include	VBG
cord-032504-tmohg1mj	104	32	increased	increase	VBN
cord-032504-tmohg1mj	104	33	surface	surface	NN
cord-032504-tmohg1mj	104	34	expression	expression	NN
cord-032504-tmohg1mj	104	35	of	of	IN
cord-032504-tmohg1mj	104	36	the	the	DT
cord-032504-tmohg1mj	104	37	HIV	HIV	NNP
cord-032504-tmohg1mj	104	38	receptors	receptor	NNS
cord-032504-tmohg1mj	104	39	CCR5	CCR5	NNP
cord-032504-tmohg1mj	104	40	and	and	CC
cord-032504-tmohg1mj	104	41	CXCR4	CXCR4	NNS
cord-032504-tmohg1mj	104	42	,	,	,
cord-032504-tmohg1mj	104	43	increased	increase	VBD
cord-032504-tmohg1mj	104	44	HIV	HIV	NNP
cord-032504-tmohg1mj	104	45	transcription	transcription	NN
cord-032504-tmohg1mj	104	46	and	and	CC
cord-032504-tmohg1mj	104	47	replication	replication	NN
cord-032504-tmohg1mj	104	48	,	,	,
cord-032504-tmohg1mj	104	49	and	and	CC
cord-032504-tmohg1mj	104	50	induction	induction	NN
cord-032504-tmohg1mj	104	51	of	of	IN
cord-032504-tmohg1mj	104	52	nanotubes	nanotube	NNS
cord-032504-tmohg1mj	104	53	that	that	WDT
cord-032504-tmohg1mj	104	54	promote	promote	VBP
cord-032504-tmohg1mj	104	55	cell	cell	NN
cord-032504-tmohg1mj	104	56	-	-	HYPH
cord-032504-tmohg1mj	104	57	to	to	IN
cord-032504-tmohg1mj	104	58	-	-	HYPH
cord-032504-tmohg1mj	104	59	cell	cell	NN
cord-032504-tmohg1mj	104	60	HIV	HIV	NNP
cord-032504-tmohg1mj	104	61	viral	viral	JJ
cord-032504-tmohg1mj	104	62	spread	spread	NN
cord-032504-tmohg1mj	104	63	between	between	IN
cord-032504-tmohg1mj	104	64	macrophages	macrophage	NNS
cord-032504-tmohg1mj	104	65	[	[	-LRB-
cord-032504-tmohg1mj	104	66	61	61	CD
cord-032504-tmohg1mj	104	67	]	]	-RRB-
cord-032504-tmohg1mj	104	68	[	[	-LRB-
cord-032504-tmohg1mj	104	69	62	62	CD
cord-032504-tmohg1mj	104	70	]	]	-RRB-
cord-032504-tmohg1mj	104	71	[	[	-LRB-
cord-032504-tmohg1mj	104	72	63	63	CD
cord-032504-tmohg1mj	104	73	]	]	-RRB-
cord-032504-tmohg1mj	104	74	[	[	-LRB-
cord-032504-tmohg1mj	104	75	64	64	CD
cord-032504-tmohg1mj	104	76	]	]	-RRB-
cord-032504-tmohg1mj	104	77	.	.	.
cord-032504-tmohg1mj	105	1	Taken	take	VBN
cord-032504-tmohg1mj	105	2	together	together	RB
cord-032504-tmohg1mj	105	3	,	,	,
cord-032504-tmohg1mj	105	4	this	this	DT
cord-032504-tmohg1mj	105	5	synergy	synergy	NN
cord-032504-tmohg1mj	105	6	between	between	IN
cord-032504-tmohg1mj	105	7	Mtb	Mtb	NNP
cord-032504-tmohg1mj	105	8	-	-	:
cord-032504-tmohg1mj	105	9	and	and	CC
cord-032504-tmohg1mj	105	10	HIV	HIV	NNP
cord-032504-tmohg1mj	105	11	-	-	HYPH
cord-032504-tmohg1mj	105	12	mediated	mediate	VBN
cord-032504-tmohg1mj	105	13	impacts	impact	NNS
cord-032504-tmohg1mj	105	14	on	on	IN
cord-032504-tmohg1mj	105	15	macrophages	macrophage	NNS
cord-032504-tmohg1mj	105	16	enables	enable	VBZ
cord-032504-tmohg1mj	105	17	intracellular	intracellular	JJ
cord-032504-tmohg1mj	105	18	growth	growth	NN
cord-032504-tmohg1mj	105	19	and	and	CC
cord-032504-tmohg1mj	105	20	survival	survival	NN
cord-032504-tmohg1mj	105	21	of	of	IN
cord-032504-tmohg1mj	105	22	both	both	DT
cord-032504-tmohg1mj	105	23	pathogens	pathogen	NNS
cord-032504-tmohg1mj	105	24	and	and	CC
cord-032504-tmohg1mj	105	25	,	,	,
cord-032504-tmohg1mj	105	26	more	more	RBR
cord-032504-tmohg1mj	105	27	broadly	broadly	RB
cord-032504-tmohg1mj	105	28	,	,	,
cord-032504-tmohg1mj	105	29	fuels	fuel	VBZ
cord-032504-tmohg1mj	105	30	the	the	DT
cord-032504-tmohg1mj	105	31	global	global	JJ
cord-032504-tmohg1mj	105	32	syndemic	syndemic	NN
cord-032504-tmohg1mj	105	33	of	of	IN
cord-032504-tmohg1mj	105	34	coinfection	coinfection	NN
cord-032504-tmohg1mj	105	35	.	.	.
cord-032504-tmohg1mj	106	1	Macrophage	macrophage	NN
cord-032504-tmohg1mj	106	2	function	function	NN
cord-032504-tmohg1mj	106	3	and	and	CC
cord-032504-tmohg1mj	106	4	polarization	polarization	NN
cord-032504-tmohg1mj	106	5	is	be	VBZ
cord-032504-tmohg1mj	106	6	also	also	RB
cord-032504-tmohg1mj	106	7	influenced	influence	VBN
cord-032504-tmohg1mj	106	8	by	by	IN
cord-032504-tmohg1mj	106	9	immunometabolism	immunometabolism	NN
cord-032504-tmohg1mj	106	10	,	,	,
cord-032504-tmohg1mj	106	11	the	the	DT
cord-032504-tmohg1mj	106	12	balance	balance	NN
cord-032504-tmohg1mj	106	13	of	of	IN
cord-032504-tmohg1mj	106	14	cellular	cellular	JJ
cord-032504-tmohg1mj	106	15	energy	energy	NN
cord-032504-tmohg1mj	106	16	utilization	utilization	NN
cord-032504-tmohg1mj	106	17	.	.	.
cord-032504-tmohg1mj	107	1	This	this	DT
cord-032504-tmohg1mj	107	2	represents	represent	VBZ
cord-032504-tmohg1mj	107	3	another	another	DT
cord-032504-tmohg1mj	107	4	growing	grow	VBG
cord-032504-tmohg1mj	107	5	area	area	NN
cord-032504-tmohg1mj	107	6	of	of	IN
cord-032504-tmohg1mj	107	7	inquiry	inquiry	NN
cord-032504-tmohg1mj	107	8	in	in	IN
cord-032504-tmohg1mj	107	9	which	which	WDT
cord-032504-tmohg1mj	107	10	Mtb	Mtb	NNP
cord-032504-tmohg1mj	107	11	and	and	CC
cord-032504-tmohg1mj	107	12	HIV	HIV	NNP
cord-032504-tmohg1mj	107	13	are	be	VBP
cord-032504-tmohg1mj	107	14	likely	likely	JJ
cord-032504-tmohg1mj	107	15	to	to	TO
cord-032504-tmohg1mj	107	16	have	have	VB
cord-032504-tmohg1mj	107	17	complementary	complementary	JJ
cord-032504-tmohg1mj	107	18	,	,	,
cord-032504-tmohg1mj	107	19	yet	yet	CC
cord-032504-tmohg1mj	107	20	deleterious	deleterious	JJ
cord-032504-tmohg1mj	107	21	,	,	,
cord-032504-tmohg1mj	107	22	effects	effect	NNS
cord-032504-tmohg1mj	107	23	.	.	.
cord-032504-tmohg1mj	108	1	Mtb	mtb	JJ
cord-032504-tmohg1mj	108	2	infection	infection	NN
cord-032504-tmohg1mj	108	3	of	of	IN
cord-032504-tmohg1mj	108	4	alveolar	alveolar	JJ
cord-032504-tmohg1mj	108	5	macrophages	macrophage	NNS
cord-032504-tmohg1mj	108	6	has	have	VBZ
cord-032504-tmohg1mj	108	7	been	be	VBN
cord-032504-tmohg1mj	108	8	shown	show	VBN
cord-032504-tmohg1mj	108	9	to	to	TO
cord-032504-tmohg1mj	108	10	shift	shift	VB
cord-032504-tmohg1mj	108	11	cellular	cellular	JJ
cord-032504-tmohg1mj	108	12	metabolism	metabolism	NN
cord-032504-tmohg1mj	108	13	from	from	IN
cord-032504-tmohg1mj	108	14	oxidative	oxidative	JJ
cord-032504-tmohg1mj	108	15	phosphorylation	phosphorylation	NN
cord-032504-tmohg1mj	108	16	to	to	IN
cord-032504-tmohg1mj	108	17	aerobic	aerobic	JJ
cord-032504-tmohg1mj	108	18	glycolysis	glycolysis	NN
cord-032504-tmohg1mj	108	19	,	,	,
cord-032504-tmohg1mj	108	20	a	a	DT
cord-032504-tmohg1mj	108	21	shift	shift	NN
cord-032504-tmohg1mj	108	22	associated	associate	VBN
cord-032504-tmohg1mj	108	23	with	with	IN
cord-032504-tmohg1mj	108	24	a	a	DT
cord-032504-tmohg1mj	108	25	more	more	RBR
cord-032504-tmohg1mj	108	26	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	108	27	,	,	,
cord-032504-tmohg1mj	108	28	M1-like	m1-like	IN
cord-032504-tmohg1mj	108	29	phenotype	phenotype	NN
cord-032504-tmohg1mj	108	30	[	[	-LRB-
cord-032504-tmohg1mj	108	31	65	65	CD
cord-032504-tmohg1mj	108	32	]	]	-RRB-
cord-032504-tmohg1mj	108	33	.	.	.
cord-032504-tmohg1mj	109	1	This	this	DT
cord-032504-tmohg1mj	109	2	shift	shift	NN
cord-032504-tmohg1mj	109	3	triggers	trigger	VBZ
cord-032504-tmohg1mj	109	4	an	an	DT
cord-032504-tmohg1mj	109	5	increase	increase	NN
cord-032504-tmohg1mj	109	6	in	in	IN
cord-032504-tmohg1mj	109	7	cellular	cellular	JJ
cord-032504-tmohg1mj	109	8	IL-1β	il-1β	NN
cord-032504-tmohg1mj	109	9	production	production	NN
cord-032504-tmohg1mj	109	10	along	along	IN
cord-032504-tmohg1mj	109	11	with	with	IN
cord-032504-tmohg1mj	109	12	a	a	DT
cord-032504-tmohg1mj	109	13	decrease	decrease	NN
cord-032504-tmohg1mj	109	14	in	in	IN
cord-032504-tmohg1mj	109	15	IL-10	IL-10	NNP
cord-032504-tmohg1mj	109	16	production	production	NN
cord-032504-tmohg1mj	109	17	,	,	,
cord-032504-tmohg1mj	109	18	which	which	WDT
cord-032504-tmohg1mj	109	19	,	,	,
cord-032504-tmohg1mj	109	20	in	in	IN
cord-032504-tmohg1mj	109	21	concert	concert	NN
cord-032504-tmohg1mj	109	22	,	,	,
cord-032504-tmohg1mj	109	23	should	should	MD
cord-032504-tmohg1mj	109	24	increase	increase	VB
cord-032504-tmohg1mj	109	25	bacillary	bacillary	NNP
cord-032504-tmohg1mj	109	26	killing	kill	VBG
cord-032504-tmohg1mj	109	27	in	in	IN
cord-032504-tmohg1mj	109	28	vitro	vitro	FW
cord-032504-tmohg1mj	109	29	.	.	.
cord-032504-tmohg1mj	110	1	Yet	yet	RB
cord-032504-tmohg1mj	110	2	,	,	,
cord-032504-tmohg1mj	110	3	other	other	JJ
cord-032504-tmohg1mj	110	4	investigations	investigation	NNS
cord-032504-tmohg1mj	110	5	suggest	suggest	VBP
cord-032504-tmohg1mj	110	6	that	that	IN
cord-032504-tmohg1mj	110	7	persistence	persistence	NN
cord-032504-tmohg1mj	110	8	of	of	IN
cord-032504-tmohg1mj	110	9	fatty	fatty	JJ
cord-032504-tmohg1mj	110	10	acid	acid	NN
cord-032504-tmohg1mj	110	11	oxidation	oxidation	NN
cord-032504-tmohg1mj	110	12	in	in	IN
cord-032504-tmohg1mj	110	13	alveolar	alveolar	JJ
cord-032504-tmohg1mj	110	14	macrophages	macrophage	NNS
cord-032504-tmohg1mj	110	15	may	may	MD
cord-032504-tmohg1mj	110	16	permit	permit	VB
cord-032504-tmohg1mj	110	17	ongoing	ongoing	JJ
cord-032504-tmohg1mj	110	18	intracellular	intracellular	JJ
cord-032504-tmohg1mj	110	19	Mtb	Mtb	NNP
cord-032504-tmohg1mj	110	20	growth	growth	NN
cord-032504-tmohg1mj	110	21	[	[	-LRB-
cord-032504-tmohg1mj	110	22	66	66	CD
cord-032504-tmohg1mj	110	23	]	]	-RRB-
cord-032504-tmohg1mj	110	24	.	.	.
cord-032504-tmohg1mj	111	1	At	at	IN
cord-032504-tmohg1mj	111	2	the	the	DT
cord-032504-tmohg1mj	111	3	same	same	JJ
cord-032504-tmohg1mj	111	4	time	time	NN
cord-032504-tmohg1mj	111	5	,	,	,
cord-032504-tmohg1mj	111	6	HIV	HIV	NNP
cord-032504-tmohg1mj	111	7	infection	infection	NN
cord-032504-tmohg1mj	111	8	also	also	RB
cord-032504-tmohg1mj	111	9	alters	alter	VBZ
cord-032504-tmohg1mj	111	10	cellular	cellular	JJ
cord-032504-tmohg1mj	111	11	energy	energy	NN
cord-032504-tmohg1mj	111	12	balance	balance	NN
cord-032504-tmohg1mj	111	13	,	,	,
cord-032504-tmohg1mj	111	14	oxidative	oxidative	JJ
cord-032504-tmohg1mj	111	15	stress	stress	NN
cord-032504-tmohg1mj	111	16	levels	level	NNS
cord-032504-tmohg1mj	111	17	,	,	,
cord-032504-tmohg1mj	111	18	and	and	CC
cord-032504-tmohg1mj	111	19	mitochondrial	mitochondrial	NN
cord-032504-tmohg1mj	111	20	bioenergetics	bioenergetic	NNS
cord-032504-tmohg1mj	111	21	,	,	,
cord-032504-tmohg1mj	111	22	including	include	VBG
cord-032504-tmohg1mj	111	23	for	for	IN
cord-032504-tmohg1mj	111	24	infected	infected	JJ
cord-032504-tmohg1mj	111	25	macrophages	macrophage	NNS
cord-032504-tmohg1mj	111	26	[	[	-LRB-
cord-032504-tmohg1mj	111	27	67	67	CD
cord-032504-tmohg1mj	111	28	]	]	-RRB-
cord-032504-tmohg1mj	111	29	[	[	-LRB-
cord-032504-tmohg1mj	111	30	68	68	CD
cord-032504-tmohg1mj	111	31	]	]	-RRB-
cord-032504-tmohg1mj	111	32	[	[	-LRB-
cord-032504-tmohg1mj	111	33	69	69	CD
cord-032504-tmohg1mj	111	34	]	]	-RRB-
cord-032504-tmohg1mj	111	35	[	[	-LRB-
cord-032504-tmohg1mj	111	36	70	70	CD
cord-032504-tmohg1mj	111	37	]	]	-RRB-
cord-032504-tmohg1mj	111	38	.	.	.
cord-032504-tmohg1mj	112	1	Further	further	JJ
cord-032504-tmohg1mj	112	2	study	study	NN
cord-032504-tmohg1mj	112	3	of	of	IN
cord-032504-tmohg1mj	112	4	the	the	DT
cord-032504-tmohg1mj	112	5	combined	combined	JJ
cord-032504-tmohg1mj	112	6	,	,	,
cord-032504-tmohg1mj	112	7	net	net	JJ
cord-032504-tmohg1mj	112	8	effects	effect	NNS
cord-032504-tmohg1mj	112	9	of	of	IN
cord-032504-tmohg1mj	112	10	Mtb	Mtb	NNP
cord-032504-tmohg1mj	112	11	and	and	CC
cord-032504-tmohg1mj	112	12	HIV	HIV	NNP
cord-032504-tmohg1mj	112	13	on	on	IN
cord-032504-tmohg1mj	112	14	alveolar	alveolar	NNP
cord-032504-tmohg1mj	112	15	macrophage	macrophage	NN
cord-032504-tmohg1mj	112	16	immunometabolism	immunometabolism	NN
cord-032504-tmohg1mj	112	17	is	be	VBZ
cord-032504-tmohg1mj	112	18	needed	need	VBN
cord-032504-tmohg1mj	112	19	to	to	TO
cord-032504-tmohg1mj	112	20	expand	expand	VB
cord-032504-tmohg1mj	112	21	our	-PRON-	PRP$
cord-032504-tmohg1mj	112	22	understanding	understanding	NN
cord-032504-tmohg1mj	112	23	of	of	IN
cord-032504-tmohg1mj	112	24	how	how	WRB
cord-032504-tmohg1mj	112	25	coinfection	coinfection	NN
cord-032504-tmohg1mj	112	26	impairs	impair	VBZ
cord-032504-tmohg1mj	112	27	early	early	JJ
cord-032504-tmohg1mj	112	28	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	112	29	control	control	NN
cord-032504-tmohg1mj	112	30	.	.	.
cord-032504-tmohg1mj	112	31	 	 	_SP
cord-032504-tmohg1mj	113	1	Macrophage	macrophage	NN
cord-032504-tmohg1mj	113	2	cytokine	cytokine	NN
cord-032504-tmohg1mj	113	3	expression	expression	NN
cord-032504-tmohg1mj	113	4	profiles	profile	NNS
cord-032504-tmohg1mj	113	5	may	may	MD
cord-032504-tmohg1mj	113	6	also	also	RB
cord-032504-tmohg1mj	113	7	vary	vary	VB
cord-032504-tmohg1mj	113	8	according	accord	VBG
cord-032504-tmohg1mj	113	9	to	to	IN
cord-032504-tmohg1mj	113	10	the	the	DT
cord-032504-tmohg1mj	113	11	stage	stage	NN
cord-032504-tmohg1mj	113	12	of	of	IN
cord-032504-tmohg1mj	113	13	Mtb	Mtb	NNP
cord-032504-tmohg1mj	113	14	infection	infection	NN
cord-032504-tmohg1mj	113	15	,	,	,
cord-032504-tmohg1mj	113	16	whereby	whereby	WRB
cord-032504-tmohg1mj	113	17	the	the	DT
cord-032504-tmohg1mj	113	18	secreted	secrete	VBN
cord-032504-tmohg1mj	113	19	protein	protein	NN
cord-032504-tmohg1mj	113	20	ESAT-6	esat-6	PRP
cord-032504-tmohg1mj	113	21	initially	initially	RB
cord-032504-tmohg1mj	113	22	skews	skew	VBZ
cord-032504-tmohg1mj	113	23	macrophages	macrophage	NNS
cord-032504-tmohg1mj	113	24	towards	towards	IN
cord-032504-tmohg1mj	113	25	a	a	DT
cord-032504-tmohg1mj	113	26	M1	M1	NNP
cord-032504-tmohg1mj	113	27	phenotype	phenotype	NN
cord-032504-tmohg1mj	113	28	,	,	,
cord-032504-tmohg1mj	113	29	potentially	potentially	RB
cord-032504-tmohg1mj	113	30	to	to	TO
cord-032504-tmohg1mj	113	31	facilitate	facilitate	VB
cord-032504-tmohg1mj	113	32	the	the	DT
cord-032504-tmohg1mj	113	33	establishment	establishment	NN
cord-032504-tmohg1mj	113	34	of	of	IN
cord-032504-tmohg1mj	113	35	a	a	DT
cord-032504-tmohg1mj	113	36	granuloma	granuloma	NN
cord-032504-tmohg1mj	113	37	,	,	,
cord-032504-tmohg1mj	113	38	and	and	CC
cord-032504-tmohg1mj	113	39	then	then	RB
cord-032504-tmohg1mj	113	40	later	later	RB
cord-032504-tmohg1mj	113	41	to	to	IN
cord-032504-tmohg1mj	113	42	a	a	DT
cord-032504-tmohg1mj	113	43	more	more	RBR
cord-032504-tmohg1mj	113	44	permissive	permissive	JJ
cord-032504-tmohg1mj	113	45	M2	m2	NN
cord-032504-tmohg1mj	113	46	phenotype	phenotype	NN
cord-032504-tmohg1mj	113	47	[	[	-LRB-
cord-032504-tmohg1mj	113	48	71	71	CD
cord-032504-tmohg1mj	113	49	]	]	-RRB-
cord-032504-tmohg1mj	113	50	.	.	.
cord-032504-tmohg1mj	114	1	IFN	IFN	NNP
cord-032504-tmohg1mj	114	2	-	-	HYPH
cord-032504-tmohg1mj	114	3	γ	γ	NNP
cord-032504-tmohg1mj	114	4	,	,	,
cord-032504-tmohg1mj	114	5	a	a	DT
cord-032504-tmohg1mj	114	6	paradigmatic	paradigmatic	JJ
cord-032504-tmohg1mj	114	7	pro	pro	JJ
cord-032504-tmohg1mj	114	8	-	-	JJ
cord-032504-tmohg1mj	114	9	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	114	10	cytokine	cytokine	NN
cord-032504-tmohg1mj	114	11	,	,	,
cord-032504-tmohg1mj	114	12	drives	drive	VBZ
cord-032504-tmohg1mj	114	13	macrophages	macrophage	NNS
cord-032504-tmohg1mj	114	14	towards	towards	IN
cord-032504-tmohg1mj	114	15	an	an	DT
cord-032504-tmohg1mj	114	16	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	114	17	phenotype	phenotype	NN
cord-032504-tmohg1mj	114	18	and	and	CC
cord-032504-tmohg1mj	114	19	,	,	,
cord-032504-tmohg1mj	114	20	under	under	IN
cord-032504-tmohg1mj	114	21	normal	normal	JJ
cord-032504-tmohg1mj	114	22	circumstances	circumstance	NNS
cord-032504-tmohg1mj	114	23	,	,	,
cord-032504-tmohg1mj	114	24	is	be	VBZ
cord-032504-tmohg1mj	114	25	critical	critical	JJ
cord-032504-tmohg1mj	114	26	for	for	IN
cord-032504-tmohg1mj	114	27	Mtb	Mtb	NNP
cord-032504-tmohg1mj	114	28	control	control	NN
cord-032504-tmohg1mj	114	29	.	.	.
cord-032504-tmohg1mj	115	1	However	however	RB
cord-032504-tmohg1mj	115	2	,	,	,
cord-032504-tmohg1mj	115	3	peripheral	peripheral	JJ
cord-032504-tmohg1mj	115	4	blood	blood	NN
cord-032504-tmohg1mj	115	5	mononuclear	mononuclear	NN
cord-032504-tmohg1mj	115	6	cells	cell	NNS
cord-032504-tmohg1mj	115	7	isolated	isolate	VBN
cord-032504-tmohg1mj	115	8	from	from	IN
cord-032504-tmohg1mj	115	9	people	people	NNS
cord-032504-tmohg1mj	115	10	with	with	IN
cord-032504-tmohg1mj	115	11	HIV	HIV	NNP
cord-032504-tmohg1mj	115	12	have	have	VBP
cord-032504-tmohg1mj	115	13	depressed	depress	VBN
cord-032504-tmohg1mj	115	14	IFN	IFN	NNP
cord-032504-tmohg1mj	115	15	-	-	HYPH
cord-032504-tmohg1mj	115	16	γ	γ	NN
cord-032504-tmohg1mj	115	17	production	production	NN
cord-032504-tmohg1mj	115	18	in	in	IN
cord-032504-tmohg1mj	115	19	response	response	NN
cord-032504-tmohg1mj	115	20	to	to	IN
cord-032504-tmohg1mj	115	21	purified	purify	VBN
cord-032504-tmohg1mj	115	22	protein	protein	NN
cord-032504-tmohg1mj	115	23	derivative	derivative	NN
cord-032504-tmohg1mj	115	24	(	(	-LRB-
cord-032504-tmohg1mj	115	25	PPD	PPD	NNP
cord-032504-tmohg1mj	115	26	)	)	-RRB-
cord-032504-tmohg1mj	115	27	[	[	-LRB-
cord-032504-tmohg1mj	115	28	72	72	CD
cord-032504-tmohg1mj	115	29	,	,	,
cord-032504-tmohg1mj	115	30	73	73	CD
cord-032504-tmohg1mj	115	31	]	]	-RRB-
cord-032504-tmohg1mj	115	32	.	.	.
cord-032504-tmohg1mj	116	1	IL-4	IL-4	NNP
cord-032504-tmohg1mj	116	2	,	,	,
cord-032504-tmohg1mj	116	3	another	another	DT
cord-032504-tmohg1mj	116	4	key	key	JJ
cord-032504-tmohg1mj	116	5	cytokine	cytokine	NN
cord-032504-tmohg1mj	116	6	for	for	IN
cord-032504-tmohg1mj	116	7	macrophage	macrophage	NN
cord-032504-tmohg1mj	116	8	polarization	polarization	NN
cord-032504-tmohg1mj	116	9	,	,	,
cord-032504-tmohg1mj	116	10	is	be	VBZ
cord-032504-tmohg1mj	116	11	induced	induce	VBN
cord-032504-tmohg1mj	116	12	by	by	IN
cord-032504-tmohg1mj	116	13	HIV	HIV	NNP
cord-032504-tmohg1mj	116	14	glycoprotein	glycoprotein	NN
cord-032504-tmohg1mj	116	15	(	(	-LRB-
cord-032504-tmohg1mj	116	16	gp	gp	NN
cord-032504-tmohg1mj	116	17	)	)	-RRB-
cord-032504-tmohg1mj	116	18	120	120	CD
cord-032504-tmohg1mj	116	19	[	[	-LRB-
cord-032504-tmohg1mj	116	20	74	74	CD
cord-032504-tmohg1mj	116	21	]	]	-RRB-
cord-032504-tmohg1mj	116	22	.	.	.
cord-032504-tmohg1mj	117	1	This	this	DT
cord-032504-tmohg1mj	117	2	induction	induction	NN
cord-032504-tmohg1mj	117	3	shifts	shift	VBZ
cord-032504-tmohg1mj	117	4	macrophages	macrophage	NNS
cord-032504-tmohg1mj	117	5	to	to	IN
cord-032504-tmohg1mj	117	6	an	an	DT
cord-032504-tmohg1mj	117	7	anti	anti	JJ
cord-032504-tmohg1mj	117	8	-	-	JJ
cord-032504-tmohg1mj	117	9	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	117	10	phenotype	phenotype	NN
cord-032504-tmohg1mj	117	11	,	,	,
cord-032504-tmohg1mj	117	12	potentially	potentially	RB
cord-032504-tmohg1mj	117	13	further	further	RB
cord-032504-tmohg1mj	117	14	reducing	reduce	VBG
cord-032504-tmohg1mj	117	15	early	early	JJ
cord-032504-tmohg1mj	117	16	Mtb	Mtb	NNP
cord-032504-tmohg1mj	117	17	control	control	NN
cord-032504-tmohg1mj	117	18	.	.	.
cord-032504-tmohg1mj	118	1	In	in	IN
cord-032504-tmohg1mj	118	2	people	people	NNS
cord-032504-tmohg1mj	118	3	without	without	IN
cord-032504-tmohg1mj	118	4	HIV	HIV	NNP
cord-032504-tmohg1mj	118	5	,	,	,
cord-032504-tmohg1mj	118	6	elevated	elevate	VBN
cord-032504-tmohg1mj	118	7	IL-4	IL-4	NNP
cord-032504-tmohg1mj	118	8	levels	level	NNS
cord-032504-tmohg1mj	118	9	have	have	VBP
cord-032504-tmohg1mj	118	10	been	be	VBN
cord-032504-tmohg1mj	118	11	associated	associate	VBN
cord-032504-tmohg1mj	118	12	with	with	IN
cord-032504-tmohg1mj	118	13	progression	progression	NN
cord-032504-tmohg1mj	118	14	to	to	IN
cord-032504-tmohg1mj	118	15	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	118	16	disease	disease	NN
cord-032504-tmohg1mj	118	17	and	and	CC
cord-032504-tmohg1mj	118	18	the	the	DT
cord-032504-tmohg1mj	118	19	development	development	NN
cord-032504-tmohg1mj	118	20	of	of	IN
cord-032504-tmohg1mj	118	21	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	118	22	cavities	cavity	NNS
cord-032504-tmohg1mj	118	23	,	,	,
cord-032504-tmohg1mj	118	24	thus	thus	RB
cord-032504-tmohg1mj	118	25	underscoring	underscore	VBG
cord-032504-tmohg1mj	118	26	the	the	DT
cord-032504-tmohg1mj	118	27	clinical	clinical	JJ
cord-032504-tmohg1mj	118	28	impact	impact	NN
cord-032504-tmohg1mj	118	29	of	of	IN
cord-032504-tmohg1mj	118	30	these	these	DT
cord-032504-tmohg1mj	118	31	shifts	shift	NNS
cord-032504-tmohg1mj	118	32	[	[	-LRB-
cord-032504-tmohg1mj	118	33	75	75	CD
cord-032504-tmohg1mj	118	34	]	]	-RRB-
cord-032504-tmohg1mj	118	35	[	[	-LRB-
cord-032504-tmohg1mj	118	36	76	76	CD
cord-032504-tmohg1mj	118	37	]	]	-RRB-
cord-032504-tmohg1mj	118	38	[	[	-LRB-
cord-032504-tmohg1mj	118	39	77	77	CD
cord-032504-tmohg1mj	118	40	]	]	-RRB-
cord-032504-tmohg1mj	118	41	.	.	.
cord-032504-tmohg1mj	119	1	Interestingly	interestingly	RB
cord-032504-tmohg1mj	119	2	,	,	,
cord-032504-tmohg1mj	119	3	the	the	DT
cord-032504-tmohg1mj	119	4	relative	relative	JJ
cord-032504-tmohg1mj	119	5	balance	balance	NN
cord-032504-tmohg1mj	119	6	of	of	IN
cord-032504-tmohg1mj	119	7	these	these	DT
cord-032504-tmohg1mj	119	8	cytokines	cytokine	NNS
cord-032504-tmohg1mj	119	9	may	may	MD
cord-032504-tmohg1mj	119	10	vary	vary	VB
cord-032504-tmohg1mj	119	11	according	accord	VBG
cord-032504-tmohg1mj	119	12	to	to	IN
cord-032504-tmohg1mj	119	13	the	the	DT
cord-032504-tmohg1mj	119	14	stage	stage	NN
cord-032504-tmohg1mj	119	15	of	of	IN
cord-032504-tmohg1mj	119	16	HIV	HIV	NNP
cord-032504-tmohg1mj	119	17	infection	infection	NN
cord-032504-tmohg1mj	119	18	,	,	,
cord-032504-tmohg1mj	119	19	which	which	WDT
cord-032504-tmohg1mj	119	20	could	could	MD
cord-032504-tmohg1mj	119	21	translate	translate	VB
cord-032504-tmohg1mj	119	22	into	into	IN
cord-032504-tmohg1mj	119	23	differential	differential	JJ
cord-032504-tmohg1mj	119	24	susceptibility	susceptibility	NN
cord-032504-tmohg1mj	119	25	to	to	IN
cord-032504-tmohg1mj	119	26	and	and	CC
cord-032504-tmohg1mj	119	27	control	control	NN
cord-032504-tmohg1mj	119	28	of	of	IN
cord-032504-tmohg1mj	119	29	Mtb	Mtb	NNP
cord-032504-tmohg1mj	119	30	infection	infection	NN
cord-032504-tmohg1mj	119	31	[	[	-LRB-
cord-032504-tmohg1mj	119	32	60	60	CD
cord-032504-tmohg1mj	119	33	]	]	-RRB-
cord-032504-tmohg1mj	119	34	.	.	.
cord-032504-tmohg1mj	120	1	Several	several	JJ
cord-032504-tmohg1mj	120	2	key	key	JJ
cord-032504-tmohg1mj	120	3	cytokines	cytokine	NNS
cord-032504-tmohg1mj	120	4	important	important	JJ
cord-032504-tmohg1mj	120	5	for	for	IN
cord-032504-tmohg1mj	120	6	both	both	DT
cord-032504-tmohg1mj	120	7	macrophage	macrophage	NN
cord-032504-tmohg1mj	120	8	polarization	polarization	NN
cord-032504-tmohg1mj	120	9	and	and	CC
cord-032504-tmohg1mj	120	10	the	the	DT
cord-032504-tmohg1mj	120	11	response	response	NN
cord-032504-tmohg1mj	120	12	to	to	IN
cord-032504-tmohg1mj	120	13	Mtb	Mtb	NNP
cord-032504-tmohg1mj	120	14	are	be	VBP
cord-032504-tmohg1mj	120	15	also	also	RB
cord-032504-tmohg1mj	120	16	altered	alter	VBN
cord-032504-tmohg1mj	120	17	in	in	IN
cord-032504-tmohg1mj	120	18	the	the	DT
cord-032504-tmohg1mj	120	19	presence	presence	NN
cord-032504-tmohg1mj	120	20	of	of	IN
cord-032504-tmohg1mj	120	21	HIV	HIV	NNP
cord-032504-tmohg1mj	120	22	coinfection	coinfection	NN
cord-032504-tmohg1mj	120	23	.	.	.
cord-032504-tmohg1mj	121	1	For	for	IN
cord-032504-tmohg1mj	121	2	example	example	NN
cord-032504-tmohg1mj	121	3	,	,	,
cord-032504-tmohg1mj	121	4	GM	GM	NNP
cord-032504-tmohg1mj	121	5	-	-	HYPH
cord-032504-tmohg1mj	121	6	CSF	CSF	NNP
cord-032504-tmohg1mj	121	7	plays	play	VBZ
cord-032504-tmohg1mj	121	8	an	an	DT
cord-032504-tmohg1mj	121	9	essential	essential	JJ
cord-032504-tmohg1mj	121	10	role	role	NN
cord-032504-tmohg1mj	121	11	in	in	IN
cord-032504-tmohg1mj	121	12	cellular	cellular	JJ
cord-032504-tmohg1mj	121	13	control	control	NN
cord-032504-tmohg1mj	121	14	of	of	IN
cord-032504-tmohg1mj	121	15	Mtb	Mtb	NNP
cord-032504-tmohg1mj	121	16	[	[	-LRB-
cord-032504-tmohg1mj	121	17	78	78	CD
cord-032504-tmohg1mj	121	18	,	,	,
cord-032504-tmohg1mj	121	19	79	79	CD
cord-032504-tmohg1mj	121	20	]	]	-RRB-
cord-032504-tmohg1mj	121	21	and	and	CC
cord-032504-tmohg1mj	121	22	its	-PRON-	PRP$
cord-032504-tmohg1mj	121	23	activity	activity	NN
cord-032504-tmohg1mj	121	24	is	be	VBZ
cord-032504-tmohg1mj	121	25	impaired	impair	VBN
cord-032504-tmohg1mj	121	26	in	in	IN
cord-032504-tmohg1mj	121	27	monocyte	monocyte	NNP
cord-032504-tmohg1mj	121	28	-	-	HYPH
cord-032504-tmohg1mj	121	29	derived	derive	VBN
cord-032504-tmohg1mj	121	30	macrophages	macrophage	NNS
cord-032504-tmohg1mj	121	31	infected	infect	VBN
cord-032504-tmohg1mj	121	32	with	with	IN
cord-032504-tmohg1mj	121	33	HIV	HIV	NNP
cord-032504-tmohg1mj	121	34	[	[	-LRB-
cord-032504-tmohg1mj	121	35	80	80	CD
cord-032504-tmohg1mj	121	36	]	]	-RRB-
cord-032504-tmohg1mj	121	37	.	.	.
cord-032504-tmohg1mj	122	1	The	the	DT
cord-032504-tmohg1mj	122	2	GM	GM	NNP
cord-032504-tmohg1mj	122	3	-	-	HYPH
cord-032504-tmohg1mj	122	4	CSF	CSF	NNP
cord-032504-tmohg1mj	122	5	:	:	:
cord-032504-tmohg1mj	123	1	M	M	NNP
cord-032504-tmohg1mj	123	2	-	-	HYPH
cord-032504-tmohg1mj	123	3	CSF	CSF	NNP
cord-032504-tmohg1mj	123	4	balance	balance	NN
cord-032504-tmohg1mj	123	5	is	be	VBZ
cord-032504-tmohg1mj	123	6	also	also	RB
cord-032504-tmohg1mj	123	7	altered	alter	VBN
cord-032504-tmohg1mj	123	8	by	by	IN
cord-032504-tmohg1mj	123	9	the	the	DT
cord-032504-tmohg1mj	123	10	presence	presence	NN
cord-032504-tmohg1mj	123	11	of	of	IN
cord-032504-tmohg1mj	123	12	Mtb	Mtb	NNP
cord-032504-tmohg1mj	123	13	[	[	-LRB-
cord-032504-tmohg1mj	123	14	81	81	CD
cord-032504-tmohg1mj	123	15	]	]	-RRB-
cord-032504-tmohg1mj	123	16	and	and	CC
cord-032504-tmohg1mj	123	17	M	M	NNP
cord-032504-tmohg1mj	123	18	-	-	HYPH
cord-032504-tmohg1mj	123	19	CSF	CSF	NNP
cord-032504-tmohg1mj	123	20	-	-	HYPH
cord-032504-tmohg1mj	123	21	driven	drive	VBN
cord-032504-tmohg1mj	123	22	macrophages	macrophage	NNS
cord-032504-tmohg1mj	123	23	are	be	VBP
cord-032504-tmohg1mj	123	24	more	more	RBR
cord-032504-tmohg1mj	123	25	permissive	permissive	JJ
cord-032504-tmohg1mj	123	26	to	to	IN
cord-032504-tmohg1mj	123	27	Mtb	Mtb	NNP
cord-032504-tmohg1mj	123	28	replication	replication	NN
cord-032504-tmohg1mj	123	29	and	and	CC
cord-032504-tmohg1mj	123	30	dissemination	dissemination	NN
cord-032504-tmohg1mj	123	31	[	[	-LRB-
cord-032504-tmohg1mj	123	32	82	82	CD
cord-032504-tmohg1mj	123	33	]	]	-RRB-
cord-032504-tmohg1mj	123	34	.	.	.
cord-032504-tmohg1mj	124	1	Similarly	similarly	RB
cord-032504-tmohg1mj	124	2	,	,	,
cord-032504-tmohg1mj	124	3	interleukin-1	interleukin-1	NNP
cord-032504-tmohg1mj	124	4	receptor	receptor	NN
cord-032504-tmohg1mj	124	5	-	-	HYPH
cord-032504-tmohg1mj	124	6	associated	associate	VBN
cord-032504-tmohg1mj	124	7	kinase	kinase	NN
cord-032504-tmohg1mj	124	8	M	M	NNP
cord-032504-tmohg1mj	124	9	(	(	-LRB-
cord-032504-tmohg1mj	124	10	IRAK	IRAK	NNP
cord-032504-tmohg1mj	124	11	-	-	HYPH
cord-032504-tmohg1mj	124	12	M	M	NNP
cord-032504-tmohg1mj	124	13	)	)	-RRB-
cord-032504-tmohg1mj	124	14	,	,	,
cord-032504-tmohg1mj	124	15	which	which	WDT
cord-032504-tmohg1mj	124	16	is	be	VBZ
cord-032504-tmohg1mj	124	17	downstream	downstream	JJ
cord-032504-tmohg1mj	124	18	of	of	IN
cord-032504-tmohg1mj	124	19	the	the	DT
cord-032504-tmohg1mj	124	20	GM	GM	NNP
cord-032504-tmohg1mj	124	21	-	-	HYPH
cord-032504-tmohg1mj	124	22	CSF	csf	NN
cord-032504-tmohg1mj	124	23	-	-	HYPH
cord-032504-tmohg1mj	124	24	dependent	dependent	JJ
cord-032504-tmohg1mj	124	25	transcription	transcription	NN
cord-032504-tmohg1mj	124	26	factor	factor	NN
cord-032504-tmohg1mj	124	27	PU.1	PU.1	NNP
cord-032504-tmohg1mj	124	28	,	,	,
cord-032504-tmohg1mj	124	29	correlates	correlate	VBZ
cord-032504-tmohg1mj	124	30	directly	directly	RB
cord-032504-tmohg1mj	124	31	with	with	IN
cord-032504-tmohg1mj	124	32	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	124	33	load	load	NN
cord-032504-tmohg1mj	124	34	in	in	IN
cord-032504-tmohg1mj	124	35	human	human	JJ
cord-032504-tmohg1mj	124	36	lung	lung	NN
cord-032504-tmohg1mj	124	37	tissue	tissue	NN
cord-032504-tmohg1mj	124	38	and	and	CC
cord-032504-tmohg1mj	124	39	impacts	impact	VBZ
cord-032504-tmohg1mj	124	40	Mtb	Mtb	NNP
cord-032504-tmohg1mj	124	41	survival	survival	NN
cord-032504-tmohg1mj	124	42	[	[	-LRB-
cord-032504-tmohg1mj	124	43	83	83	CD
cord-032504-tmohg1mj	124	44	]	]	-RRB-
cord-032504-tmohg1mj	124	45	.	.	.
cord-032504-tmohg1mj	125	1	Thus	thus	RB
cord-032504-tmohg1mj	125	2	,	,	,
cord-032504-tmohg1mj	125	3	the	the	DT
cord-032504-tmohg1mj	125	4	combined	combined	JJ
cord-032504-tmohg1mj	125	5	impact	impact	NN
cord-032504-tmohg1mj	125	6	of	of	IN
cord-032504-tmohg1mj	125	7	Mtb	Mtb	NNP
cord-032504-tmohg1mj	125	8	and	and	CC
cord-032504-tmohg1mj	125	9	HIV	HIV	NNP
cord-032504-tmohg1mj	125	10	on	on	IN
cord-032504-tmohg1mj	125	11	the	the	DT
cord-032504-tmohg1mj	125	12	balance	balance	NN
cord-032504-tmohg1mj	125	13	of	of	IN
cord-032504-tmohg1mj	125	14	cytokines	cytokine	NNS
cord-032504-tmohg1mj	125	15	within	within	IN
cord-032504-tmohg1mj	125	16	the	the	DT
cord-032504-tmohg1mj	125	17	lungs	lung	NNS
cord-032504-tmohg1mj	125	18	leads	lead	VBZ
cord-032504-tmohg1mj	125	19	to	to	IN
cord-032504-tmohg1mj	125	20	an	an	DT
cord-032504-tmohg1mj	125	21	environment	environment	NN
cord-032504-tmohg1mj	125	22	that	that	WDT
cord-032504-tmohg1mj	125	23	permits	permit	VBZ
cord-032504-tmohg1mj	125	24	the	the	DT
cord-032504-tmohg1mj	125	25	growth	growth	NN
cord-032504-tmohg1mj	125	26	of	of	IN
cord-032504-tmohg1mj	125	27	both	both	DT
cord-032504-tmohg1mj	125	28	pathogens	pathogen	NNS
cord-032504-tmohg1mj	125	29	.	.	.
cord-032504-tmohg1mj	126	1	Another	another	DT
cord-032504-tmohg1mj	126	2	avenue	avenue	NN
cord-032504-tmohg1mj	126	3	ripe	ripe	JJ
cord-032504-tmohg1mj	126	4	for	for	IN
cord-032504-tmohg1mj	126	5	further	further	JJ
cord-032504-tmohg1mj	126	6	exploration	exploration	NN
cord-032504-tmohg1mj	126	7	is	be	VBZ
cord-032504-tmohg1mj	126	8	the	the	DT
cord-032504-tmohg1mj	126	9	effects	effect	NNS
cord-032504-tmohg1mj	126	10	of	of	IN
cord-032504-tmohg1mj	126	11	HIV	HIV	NNP
cord-032504-tmohg1mj	126	12	and	and	CC
cord-032504-tmohg1mj	126	13	Mtb	Mtb	NNP
cord-032504-tmohg1mj	126	14	on	on	IN
cord-032504-tmohg1mj	126	15	redox	redox	JJ
cord-032504-tmohg1mj	126	16	systems	system	NNS
cord-032504-tmohg1mj	126	17	,	,	,
cord-032504-tmohg1mj	126	18	which	which	WDT
cord-032504-tmohg1mj	126	19	can	can	MD
cord-032504-tmohg1mj	126	20	also	also	RB
cord-032504-tmohg1mj	126	21	modulate	modulate	VB
cord-032504-tmohg1mj	126	22	macrophage	macrophage	NN
cord-032504-tmohg1mj	126	23	function	function	NN
cord-032504-tmohg1mj	126	24	[	[	-LRB-
cord-032504-tmohg1mj	126	25	84	84	CD
cord-032504-tmohg1mj	126	26	]	]	-RRB-
cord-032504-tmohg1mj	126	27	[	[	-LRB-
cord-032504-tmohg1mj	126	28	85	85	CD
cord-032504-tmohg1mj	126	29	]	]	-RRB-
cord-032504-tmohg1mj	126	30	[	[	-LRB-
cord-032504-tmohg1mj	126	31	86	86	CD
cord-032504-tmohg1mj	126	32	]	]	-RRB-
cord-032504-tmohg1mj	126	33	.	.	.
cord-032504-tmohg1mj	127	1	HIV	HIV	NNP
cord-032504-tmohg1mj	127	2	is	be	VBZ
cord-032504-tmohg1mj	127	3	known	know	VBN
cord-032504-tmohg1mj	127	4	to	to	TO
cord-032504-tmohg1mj	127	5	impair	impair	VB
cord-032504-tmohg1mj	127	6	antioxidant	antioxidant	JJ
cord-032504-tmohg1mj	127	7	defenses	defense	NNS
cord-032504-tmohg1mj	127	8	in	in	IN
cord-032504-tmohg1mj	127	9	the	the	DT
cord-032504-tmohg1mj	127	10	alveolar	alveolar	JJ
cord-032504-tmohg1mj	127	11	macrophage	macrophage	NN
cord-032504-tmohg1mj	127	12	and	and	CC
cord-032504-tmohg1mj	127	13	raise	raise	VB
cord-032504-tmohg1mj	127	14	levels	level	NNS
cord-032504-tmohg1mj	127	15	of	of	IN
cord-032504-tmohg1mj	127	16	oxidative	oxidative	JJ
cord-032504-tmohg1mj	127	17	stress	stress	NN
cord-032504-tmohg1mj	127	18	in	in	IN
cord-032504-tmohg1mj	127	19	the	the	DT
cord-032504-tmohg1mj	127	20	lung	lung	NN
cord-032504-tmohg1mj	127	21	more	more	RBR
cord-032504-tmohg1mj	127	22	generally	generally	RB
cord-032504-tmohg1mj	127	23	[	[	-LRB-
cord-032504-tmohg1mj	127	24	18	18	CD
cord-032504-tmohg1mj	127	25	,	,	,
cord-032504-tmohg1mj	127	26	87	87	CD
cord-032504-tmohg1mj	127	27	]	]	-RRB-
cord-032504-tmohg1mj	127	28	.	.	.
cord-032504-tmohg1mj	128	1	The	the	DT
cord-032504-tmohg1mj	128	2	effects	effect	NNS
cord-032504-tmohg1mj	128	3	in	in	IN
cord-032504-tmohg1mj	128	4	the	the	DT
cord-032504-tmohg1mj	128	5	lung	lung	NN
cord-032504-tmohg1mj	128	6	are	be	VBP
cord-032504-tmohg1mj	128	7	likely	likely	JJ
cord-032504-tmohg1mj	128	8	due	due	JJ
cord-032504-tmohg1mj	128	9	,	,	,
cord-032504-tmohg1mj	128	10	at	at	IN
cord-032504-tmohg1mj	128	11	least	least	JJS
cord-032504-tmohg1mj	128	12	in	in	IN
cord-032504-tmohg1mj	128	13	part	part	NN
cord-032504-tmohg1mj	128	14	,	,	,
cord-032504-tmohg1mj	128	15	to	to	IN
cord-032504-tmohg1mj	128	16	glutathione	glutathione	NN
cord-032504-tmohg1mj	128	17	depletion	depletion	NN
cord-032504-tmohg1mj	128	18	in	in	IN
cord-032504-tmohg1mj	128	19	the	the	DT
cord-032504-tmohg1mj	128	20	airways	airway	NNS
cord-032504-tmohg1mj	128	21	of	of	IN
cord-032504-tmohg1mj	128	22	people	people	NNS
cord-032504-tmohg1mj	128	23	with	with	IN
cord-032504-tmohg1mj	128	24	HIV	HIV	NNP
cord-032504-tmohg1mj	128	25	[	[	-LRB-
cord-032504-tmohg1mj	128	26	88	88	CD
cord-032504-tmohg1mj	128	27	,	,	,
cord-032504-tmohg1mj	128	28	89	89	CD
cord-032504-tmohg1mj	128	29	]	]	-RRB-
cord-032504-tmohg1mj	128	30	.	.	.
cord-032504-tmohg1mj	129	1	Mtb	Mtb	NNP
cord-032504-tmohg1mj	129	2	,	,	,
cord-032504-tmohg1mj	129	3	on	on	IN
cord-032504-tmohg1mj	129	4	the	the	DT
cord-032504-tmohg1mj	129	5	other	other	JJ
cord-032504-tmohg1mj	129	6	hand	hand	NN
cord-032504-tmohg1mj	129	7	,	,	,
cord-032504-tmohg1mj	129	8	has	have	VBZ
cord-032504-tmohg1mj	129	9	successfully	successfully	RB
cord-032504-tmohg1mj	129	10	adapted	adapt	VBN
cord-032504-tmohg1mj	129	11	to	to	IN
cord-032504-tmohg1mj	129	12	hostile	hostile	JJ
cord-032504-tmohg1mj	129	13	intracellular	intracellular	JJ
cord-032504-tmohg1mj	129	14	conditions	condition	NNS
cord-032504-tmohg1mj	129	15	,	,	,
cord-032504-tmohg1mj	129	16	including	include	VBG
cord-032504-tmohg1mj	129	17	high	high	JJ
cord-032504-tmohg1mj	129	18	oxidative	oxidative	JJ
cord-032504-tmohg1mj	129	19	stress	stress	NN
cord-032504-tmohg1mj	129	20	[	[	-LRB-
cord-032504-tmohg1mj	129	21	90	90	CD
cord-032504-tmohg1mj	129	22	,	,	,
cord-032504-tmohg1mj	129	23	91	91	CD
cord-032504-tmohg1mj	129	24	]	]	-RRB-
cord-032504-tmohg1mj	129	25	.	.	.
cord-032504-tmohg1mj	130	1	Mtb	Mtb	NNP
cord-032504-tmohg1mj	130	2	may	may	MD
cord-032504-tmohg1mj	130	3	also	also	RB
cord-032504-tmohg1mj	130	4	directly	directly	RB
cord-032504-tmohg1mj	130	5	contribute	contribute	VB
cord-032504-tmohg1mj	130	6	to	to	IN
cord-032504-tmohg1mj	130	7	oxidative	oxidative	JJ
cord-032504-tmohg1mj	130	8	stress	stress	NN
cord-032504-tmohg1mj	130	9	by	by	IN
cord-032504-tmohg1mj	130	10	inducing	induce	VBG
cord-032504-tmohg1mj	130	11	heme	heme	NN
cord-032504-tmohg1mj	130	12	oxygenase	oxygenase	NN
cord-032504-tmohg1mj	130	13	(	(	-LRB-
cord-032504-tmohg1mj	130	14	HO)-1	HO)-1	NNP
cord-032504-tmohg1mj	130	15	,	,	,
cord-032504-tmohg1mj	130	16	the	the	DT
cord-032504-tmohg1mj	130	17	levels	level	NNS
cord-032504-tmohg1mj	130	18	of	of	IN
cord-032504-tmohg1mj	130	19	which	which	WDT
cord-032504-tmohg1mj	130	20	directly	directly	RB
cord-032504-tmohg1mj	130	21	correlate	correlate	VBP
cord-032504-tmohg1mj	130	22	with	with	IN
cord-032504-tmohg1mj	130	23	treatment	treatment	NN
cord-032504-tmohg1mj	130	24	outcomes	outcome	NNS
cord-032504-tmohg1mj	130	25	in	in	IN
cord-032504-tmohg1mj	130	26	people	people	NNS
cord-032504-tmohg1mj	130	27	with	with	IN
cord-032504-tmohg1mj	130	28	active	active	JJ
cord-032504-tmohg1mj	130	29	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	130	30	disease	disease	NN
cord-032504-tmohg1mj	130	31	[	[	-LRB-
cord-032504-tmohg1mj	130	32	92	92	CD
cord-032504-tmohg1mj	130	33	]	]	-RRB-
cord-032504-tmohg1mj	130	34	.	.	.
cord-032504-tmohg1mj	131	1	Several	several	JJ
cord-032504-tmohg1mj	131	2	studies	study	NNS
cord-032504-tmohg1mj	131	3	have	have	VBP
cord-032504-tmohg1mj	131	4	demonstrated	demonstrate	VBN
cord-032504-tmohg1mj	131	5	improved	improve	VBN
cord-032504-tmohg1mj	131	6	Mtb	Mtb	NNP
cord-032504-tmohg1mj	131	7	control	control	NN
cord-032504-tmohg1mj	131	8	with	with	IN
cord-032504-tmohg1mj	131	9	glutathione	glutathione	NN
cord-032504-tmohg1mj	131	10	supplementation	supplementation	NN
cord-032504-tmohg1mj	131	11	,	,	,
cord-032504-tmohg1mj	131	12	including	include	VBG
cord-032504-tmohg1mj	131	13	one	one	CD
cord-032504-tmohg1mj	131	14	study	study	NN
cord-032504-tmohg1mj	131	15	using	use	VBG
cord-032504-tmohg1mj	131	16	macrophages	macrophage	NNS
cord-032504-tmohg1mj	131	17	isolated	isolate	VBN
cord-032504-tmohg1mj	131	18	from	from	IN
cord-032504-tmohg1mj	131	19	people	people	NNS
cord-032504-tmohg1mj	131	20	with	with	IN
cord-032504-tmohg1mj	131	21	HIV	HIV	NNP
cord-032504-tmohg1mj	131	22	in	in	IN
cord-032504-tmohg1mj	131	23	which	which	WDT
cord-032504-tmohg1mj	131	24	supplementation	supplementation	NN
cord-032504-tmohg1mj	131	25	led	lead	VBD
cord-032504-tmohg1mj	131	26	to	to	IN
cord-032504-tmohg1mj	131	27	enhanced	enhance	VBN
cord-032504-tmohg1mj	131	28	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	131	29	cytokine	cytokine	NN
cord-032504-tmohg1mj	131	30	production	production	NN
cord-032504-tmohg1mj	131	31	and	and	CC
cord-032504-tmohg1mj	131	32	restored	restore	VBN
cord-032504-tmohg1mj	131	33	macrophage	macrophage	NN
cord-032504-tmohg1mj	131	34	capacity	capacity	NN
cord-032504-tmohg1mj	131	35	to	to	TO
cord-032504-tmohg1mj	131	36	control	control	VB
cord-032504-tmohg1mj	131	37	Mtb	Mtb	NNP
cord-032504-tmohg1mj	131	38	growth	growth	NN
cord-032504-tmohg1mj	131	39	[	[	-LRB-
cord-032504-tmohg1mj	131	40	89	89	CD
cord-032504-tmohg1mj	131	41	,	,	,
cord-032504-tmohg1mj	131	42	[	[	-LRB-
cord-032504-tmohg1mj	131	43	93	93	CD
cord-032504-tmohg1mj	131	44	]	]	-RRB-
cord-032504-tmohg1mj	131	45	[	[	-LRB-
cord-032504-tmohg1mj	131	46	94	94	CD
cord-032504-tmohg1mj	131	47	]	]	-RRB-
cord-032504-tmohg1mj	131	48	[	[	-LRB-
cord-032504-tmohg1mj	131	49	95	95	CD
cord-032504-tmohg1mj	131	50	]	]	-RRB-
cord-032504-tmohg1mj	131	51	[	[	-LRB-
cord-032504-tmohg1mj	131	52	96	96	CD
cord-032504-tmohg1mj	131	53	]	]	-RRB-
cord-032504-tmohg1mj	131	54	[	[	-LRB-
cord-032504-tmohg1mj	131	55	97	97	CD
cord-032504-tmohg1mj	131	56	]	]	-RRB-
cord-032504-tmohg1mj	131	57	.	.	.
cord-032504-tmohg1mj	132	1	Of	of	IN
cord-032504-tmohg1mj	132	2	note	note	NN
cord-032504-tmohg1mj	132	3	,	,	,
cord-032504-tmohg1mj	132	4	the	the	DT
cord-032504-tmohg1mj	132	5	oxidative	oxidative	JJ
cord-032504-tmohg1mj	132	6	stress	stress	NN
cord-032504-tmohg1mj	132	7	induced	induce	VBN
cord-032504-tmohg1mj	132	8	by	by	IN
cord-032504-tmohg1mj	132	9	Mtb	Mtb	NNP
cord-032504-tmohg1mj	132	10	-	-	HYPH
cord-032504-tmohg1mj	132	11	infected	infect	VBN
cord-032504-tmohg1mj	132	12	macrophages	macrophage	NNS
cord-032504-tmohg1mj	132	13	is	be	VBZ
cord-032504-tmohg1mj	132	14	also	also	RB
cord-032504-tmohg1mj	132	15	likely	likely	JJ
cord-032504-tmohg1mj	132	16	to	to	TO
cord-032504-tmohg1mj	132	17	promote	promote	VB
cord-032504-tmohg1mj	132	18	HIV	HIV	NNP
cord-032504-tmohg1mj	132	19	reactivation	reactivation	NN
cord-032504-tmohg1mj	132	20	,	,	,
cord-032504-tmohg1mj	132	21	further	further	RB
cord-032504-tmohg1mj	132	22	complicating	complicate	VBG
cord-032504-tmohg1mj	132	23	the	the	DT
cord-032504-tmohg1mj	132	24	relationship	relationship	NN
cord-032504-tmohg1mj	132	25	between	between	IN
cord-032504-tmohg1mj	132	26	these	these	DT
cord-032504-tmohg1mj	132	27	two	two	CD
cord-032504-tmohg1mj	132	28	pathogens	pathogen	NNS
cord-032504-tmohg1mj	132	29	[	[	-LRB-
cord-032504-tmohg1mj	132	30	98	98	CD
cord-032504-tmohg1mj	132	31	]	]	-RRB-
cord-032504-tmohg1mj	132	32	.	.	.
cord-032504-tmohg1mj	133	1	An	an	DT
cord-032504-tmohg1mj	133	2	important	important	JJ
cord-032504-tmohg1mj	133	3	function	function	NN
cord-032504-tmohg1mj	133	4	of	of	IN
cord-032504-tmohg1mj	133	5	macrophages	macrophage	NNS
cord-032504-tmohg1mj	133	6	in	in	IN
cord-032504-tmohg1mj	133	7	the	the	DT
cord-032504-tmohg1mj	133	8	alveolar	alveolar	JJ
cord-032504-tmohg1mj	133	9	space	space	NN
cord-032504-tmohg1mj	133	10	is	be	VBZ
cord-032504-tmohg1mj	133	11	the	the	DT
cord-032504-tmohg1mj	133	12	differentiation	differentiation	NN
cord-032504-tmohg1mj	133	13	of	of	IN
cord-032504-tmohg1mj	133	14	friend	friend	NN
cord-032504-tmohg1mj	133	15	versus	versus	IN
cord-032504-tmohg1mj	133	16	foe	foe	NN
cord-032504-tmohg1mj	133	17	via	via	IN
cord-032504-tmohg1mj	133	18	pathogen	pathogen	NN
cord-032504-tmohg1mj	133	19	recognition	recognition	NN
cord-032504-tmohg1mj	133	20	and	and	CC
cord-032504-tmohg1mj	133	21	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	133	22	(	(	-LRB-
cord-032504-tmohg1mj	133	23	Fig	fig	NN
cord-032504-tmohg1mj	133	24	.	.	.
cord-032504-tmohg1mj	133	25	3	3	CD
cord-032504-tmohg1mj	133	26	)	)	-RRB-
cord-032504-tmohg1mj	134	1	[	[	-LRB-
cord-032504-tmohg1mj	134	2	99	99	CD
cord-032504-tmohg1mj	134	3	]	]	-RRB-
cord-032504-tmohg1mj	134	4	[	[	-LRB-
cord-032504-tmohg1mj	134	5	100	100	CD
cord-032504-tmohg1mj	134	6	]	]	-RRB-
cord-032504-tmohg1mj	134	7	[	[	-LRB-
cord-032504-tmohg1mj	134	8	101	101	CD
cord-032504-tmohg1mj	134	9	]	]	-RRB-
cord-032504-tmohg1mj	134	10	.	.	.
cord-032504-tmohg1mj	135	1	Particularly	particularly	RB
cord-032504-tmohg1mj	135	2	germane	germane	JJ
cord-032504-tmohg1mj	135	3	to	to	IN
cord-032504-tmohg1mj	135	4	the	the	DT
cord-032504-tmohg1mj	135	5	recognition	recognition	NN
cord-032504-tmohg1mj	135	6	of	of	IN
cord-032504-tmohg1mj	135	7	Mtb	Mtb	NNP
cord-032504-tmohg1mj	135	8	is	be	VBZ
cord-032504-tmohg1mj	135	9	the	the	DT
cord-032504-tmohg1mj	135	10	mannose	mannose	NN
cord-032504-tmohg1mj	135	11	receptor	receptor	NN
cord-032504-tmohg1mj	135	12	,	,	,
cord-032504-tmohg1mj	135	13	which	which	WDT
cord-032504-tmohg1mj	135	14	is	be	VBZ
cord-032504-tmohg1mj	135	15	downregulated	downregulate	VBN
cord-032504-tmohg1mj	135	16	in	in	IN
cord-032504-tmohg1mj	135	17	people	people	NNS
cord-032504-tmohg1mj	135	18	living	live	VBG
cord-032504-tmohg1mj	135	19	with	with	IN
cord-032504-tmohg1mj	135	20	HIV	HIV	NNP
cord-032504-tmohg1mj	135	21	[	[	-LRB-
cord-032504-tmohg1mj	135	22	102	102	CD
cord-032504-tmohg1mj	135	23	]	]	-RRB-
cord-032504-tmohg1mj	135	24	.	.	.
cord-032504-tmohg1mj	136	1	HIV	HIV	NNP
cord-032504-tmohg1mj	136	2	also	also	RB
cord-032504-tmohg1mj	136	3	leads	lead	VBZ
cord-032504-tmohg1mj	136	4	to	to	IN
cord-032504-tmohg1mj	136	5	reduced	reduce	VBN
cord-032504-tmohg1mj	136	6	expression	expression	NN
cord-032504-tmohg1mj	136	7	and	and	CC
cord-032504-tmohg1mj	136	8	activity	activity	NN
cord-032504-tmohg1mj	136	9	of	of	IN
cord-032504-tmohg1mj	136	10	toll	toll	NN
cord-032504-tmohg1mj	136	11	-	-	HYPH
cord-032504-tmohg1mj	136	12	like	like	JJ
cord-032504-tmohg1mj	136	13	receptors	receptor	NNS
cord-032504-tmohg1mj	136	14	(	(	-LRB-
cord-032504-tmohg1mj	136	15	TLR	TLR	NNP
cord-032504-tmohg1mj	136	16	)	)	-RRB-
cord-032504-tmohg1mj	136	17	,	,	,
cord-032504-tmohg1mj	136	18	another	another	DT
cord-032504-tmohg1mj	136	19	key	key	JJ
cord-032504-tmohg1mj	136	20	receptor	receptor	NN
cord-032504-tmohg1mj	136	21	for	for	IN
cord-032504-tmohg1mj	136	22	macrophage	macrophage	NN
cord-032504-tmohg1mj	136	23	pathogen	pathogen	NN
cord-032504-tmohg1mj	136	24	recognition	recognition	NN
cord-032504-tmohg1mj	136	25	[	[	-LRB-
cord-032504-tmohg1mj	136	26	103	103	CD
cord-032504-tmohg1mj	136	27	]	]	-RRB-
cord-032504-tmohg1mj	136	28	[	[	-LRB-
cord-032504-tmohg1mj	136	29	104	104	CD
cord-032504-tmohg1mj	136	30	]	]	-RRB-
cord-032504-tmohg1mj	137	1	[	[	-LRB-
cord-032504-tmohg1mj	137	2	105	105	CD
cord-032504-tmohg1mj	137	3	]	]	-RRB-
cord-032504-tmohg1mj	137	4	.	.	.
cord-032504-tmohg1mj	138	1	When	when	WRB
cord-032504-tmohg1mj	138	2	combined	combine	VBN
cord-032504-tmohg1mj	138	3	with	with	IN
cord-032504-tmohg1mj	138	4	shifts	shift	NNS
cord-032504-tmohg1mj	138	5	in	in	IN
cord-032504-tmohg1mj	138	6	TLR	TLR	NNP
cord-032504-tmohg1mj	138	7	-	-	HYPH
cord-032504-tmohg1mj	138	8	mediated	mediate	VBN
cord-032504-tmohg1mj	138	9	regulation	regulation	NN
cord-032504-tmohg1mj	138	10	of	of	IN
cord-032504-tmohg1mj	138	11	nitric	nitric	NN
cord-032504-tmohg1mj	138	12	oxide	oxide	NN
cord-032504-tmohg1mj	138	13	production	production	NN
cord-032504-tmohg1mj	138	14	induced	induce	VBN
cord-032504-tmohg1mj	138	15	by	by	IN
cord-032504-tmohg1mj	138	16	Mtb	Mtb	NNP
cord-032504-tmohg1mj	138	17	[	[	-LRB-
cord-032504-tmohg1mj	138	18	104	104	CD
cord-032504-tmohg1mj	138	19	]	]	-RRB-
cord-032504-tmohg1mj	138	20	,	,	,
cord-032504-tmohg1mj	138	21	these	these	DT
cord-032504-tmohg1mj	138	22	impairments	impairment	NNS
cord-032504-tmohg1mj	138	23	have	have	VBP
cord-032504-tmohg1mj	138	24	the	the	DT
cord-032504-tmohg1mj	138	25	potential	potential	NN
cord-032504-tmohg1mj	138	26	to	to	TO
cord-032504-tmohg1mj	138	27	reduce	reduce	VB
cord-032504-tmohg1mj	138	28	Mtb	Mtb	NNP
cord-032504-tmohg1mj	138	29	uptake	uptake	NN
cord-032504-tmohg1mj	138	30	by	by	IN
cord-032504-tmohg1mj	138	31	alveolar	alveolar	JJ
cord-032504-tmohg1mj	138	32	macrophages	macrophage	NNS
cord-032504-tmohg1mj	138	33	and	and	CC
cord-032504-tmohg1mj	138	34	facilitate	facilitate	VBP
cord-032504-tmohg1mj	138	35	prolonged	prolong	VBN
cord-032504-tmohg1mj	138	36	extracellular	extracellular	JJ
cord-032504-tmohg1mj	138	37	growth	growth	NN
cord-032504-tmohg1mj	138	38	.	.	.
cord-032504-tmohg1mj	139	1	Once	once	RB
cord-032504-tmohg1mj	139	2	a	a	DT
cord-032504-tmohg1mj	139	3	pathogen	pathogen	NN
cord-032504-tmohg1mj	139	4	like	like	IN
cord-032504-tmohg1mj	139	5	Mtb	Mtb	NNP
cord-032504-tmohg1mj	139	6	has	have	VBZ
cord-032504-tmohg1mj	139	7	been	be	VBN
cord-032504-tmohg1mj	139	8	recognized	recognize	VBN
cord-032504-tmohg1mj	139	9	,	,	,
cord-032504-tmohg1mj	139	10	it	-PRON-	PRP
cord-032504-tmohg1mj	139	11	then	then	RB
cord-032504-tmohg1mj	139	12	undergoes	undergo	VBZ
cord-032504-tmohg1mj	139	13	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	139	14	[	[	-LRB-
cord-032504-tmohg1mj	139	15	99	99	CD
cord-032504-tmohg1mj	139	16	,	,	,
cord-032504-tmohg1mj	139	17	100	100	CD
cord-032504-tmohg1mj	139	18	]	]	-RRB-
cord-032504-tmohg1mj	139	19	.	.	.
cord-032504-tmohg1mj	140	1	HIV	HIV	NNP
cord-032504-tmohg1mj	140	2	creates	create	VBZ
cord-032504-tmohg1mj	140	3	favorable	favorable	JJ
cord-032504-tmohg1mj	140	4	conditions	condition	NNS
cord-032504-tmohg1mj	140	5	for	for	IN
cord-032504-tmohg1mj	140	6	bacteria	bacteria	NNS
cord-032504-tmohg1mj	140	7	by	by	IN
cord-032504-tmohg1mj	140	8	impairing	impair	VBG
cord-032504-tmohg1mj	140	9	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	140	10	of	of	IN
cord-032504-tmohg1mj	140	11	pathogens	pathogen	NNS
cord-032504-tmohg1mj	140	12	including	include	VBG
cord-032504-tmohg1mj	140	13	Streptococcus	Streptococcus	NNP
cord-032504-tmohg1mj	140	14	[	[	-LRB-
cord-032504-tmohg1mj	140	15	106	106	CD
cord-032504-tmohg1mj	140	16	]	]	-RRB-
cord-032504-tmohg1mj	140	17	.	.	.
cord-032504-tmohg1mj	141	1	The	the	DT
cord-032504-tmohg1mj	141	2	HIV	HIV	NNP
cord-032504-tmohg1mj	141	3	protein	protein	NN
cord-032504-tmohg1mj	141	4	Nef	Nef	NNP
cord-032504-tmohg1mj	141	5	has	have	VBZ
cord-032504-tmohg1mj	141	6	also	also	RB
cord-032504-tmohg1mj	141	7	been	be	VBN
cord-032504-tmohg1mj	141	8	shown	show	VBN
cord-032504-tmohg1mj	141	9	to	to	TO
cord-032504-tmohg1mj	141	10	interfere	interfere	VB
cord-032504-tmohg1mj	141	11	with	with	IN
cord-032504-tmohg1mj	141	12	phagosome	phagosome	NN
cord-032504-tmohg1mj	141	13	formation	formation	NN
cord-032504-tmohg1mj	141	14	by	by	IN
cord-032504-tmohg1mj	141	15	impeding	impede	VBG
cord-032504-tmohg1mj	141	16	endosomal	endosomal	NNP
cord-032504-tmohg1mj	141	17	recruitment	recruitment	NN
cord-032504-tmohg1mj	141	18	and	and	CC
cord-032504-tmohg1mj	141	19	remodeling	remodeling	NN
cord-032504-tmohg1mj	141	20	[	[	-LRB-
cord-032504-tmohg1mj	141	21	107	107	CD
cord-032504-tmohg1mj	141	22	]	]	-RRB-
cord-032504-tmohg1mj	141	23	.	.	.
cord-032504-tmohg1mj	142	1	Of	of	IN
cord-032504-tmohg1mj	142	2	note	note	VB
cord-032504-tmohg1mj	142	3	,	,	,
cord-032504-tmohg1mj	142	4	impaired	impaired	JJ
cord-032504-tmohg1mj	142	5	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	142	6	has	have	VBZ
cord-032504-tmohg1mj	142	7	been	be	VBN
cord-032504-tmohg1mj	142	8	observed	observe	VBN
cord-032504-tmohg1mj	142	9	even	even	RB
cord-032504-tmohg1mj	142	10	in	in	IN
cord-032504-tmohg1mj	142	11	alveolar	alveolar	JJ
cord-032504-tmohg1mj	142	12	macrophages	macrophage	NNS
cord-032504-tmohg1mj	142	13	not	not	RB
cord-032504-tmohg1mj	142	14	directly	directly	RB
cord-032504-tmohg1mj	142	15	infected	infect	VBN
cord-032504-tmohg1mj	142	16	by	by	IN
cord-032504-tmohg1mj	142	17	HIV	HIV	NNP
cord-032504-tmohg1mj	142	18	[	[	-LRB-
cord-032504-tmohg1mj	142	19	58	58	CD
cord-032504-tmohg1mj	142	20	,	,	,
cord-032504-tmohg1mj	142	21	108	108	CD
cord-032504-tmohg1mj	142	22	]	]	-RRB-
cord-032504-tmohg1mj	142	23	.	.	.
cord-032504-tmohg1mj	143	1	While	while	IN
cord-032504-tmohg1mj	143	2	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	143	3	of	of	IN
cord-032504-tmohg1mj	143	4	Mtb	Mtb	NNP
cord-032504-tmohg1mj	143	5	in	in	IN
cord-032504-tmohg1mj	143	6	the	the	DT
cord-032504-tmohg1mj	143	7	setting	setting	NN
cord-032504-tmohg1mj	143	8	of	of	IN
cord-032504-tmohg1mj	143	9	HIV	HIV	NNP
cord-032504-tmohg1mj	143	10	has	have	VBZ
cord-032504-tmohg1mj	143	11	not	not	RB
cord-032504-tmohg1mj	143	12	specifically	specifically	RB
cord-032504-tmohg1mj	143	13	been	be	VBN
cord-032504-tmohg1mj	143	14	studied	study	VBN
cord-032504-tmohg1mj	143	15	,	,	,
cord-032504-tmohg1mj	143	16	such	such	JJ
cord-032504-tmohg1mj	143	17	impairments	impairment	NNS
cord-032504-tmohg1mj	143	18	would	would	MD
cord-032504-tmohg1mj	143	19	enable	enable	VB
cord-032504-tmohg1mj	143	20	further	further	JJ
cord-032504-tmohg1mj	143	21	extracellular	extracellular	JJ
cord-032504-tmohg1mj	143	22	growth	growth	NN
cord-032504-tmohg1mj	143	23	[	[	-LRB-
cord-032504-tmohg1mj	143	24	18	18	CD
cord-032504-tmohg1mj	143	25	,	,	,
cord-032504-tmohg1mj	143	26	109	109	CD
cord-032504-tmohg1mj	143	27	]	]	-RRB-
cord-032504-tmohg1mj	143	28	.	.	.
cord-032504-tmohg1mj	144	1	HIV	HIV	NNP
cord-032504-tmohg1mj	144	2	has	have	VBZ
cord-032504-tmohg1mj	144	3	also	also	RB
cord-032504-tmohg1mj	144	4	been	be	VBN
cord-032504-tmohg1mj	144	5	found	find	VBN
cord-032504-tmohg1mj	144	6	in	in	IN
cord-032504-tmohg1mj	144	7	macrophage	macrophage	NN
cord-032504-tmohg1mj	144	8	endosomes	endosome	NNS
cord-032504-tmohg1mj	144	9	and	and	CC
cord-032504-tmohg1mj	144	10	is	be	VBZ
cord-032504-tmohg1mj	144	11	known	know	VBN
cord-032504-tmohg1mj	144	12	to	to	TO
cord-032504-tmohg1mj	144	13	impair	impair	VB
cord-032504-tmohg1mj	144	14	phagolysosomal	phagolysosomal	JJ
cord-032504-tmohg1mj	144	15	fusion	fusion	NN
cord-032504-tmohg1mj	144	16	in	in	IN
cord-032504-tmohg1mj	144	17	the	the	DT
cord-032504-tmohg1mj	144	18	macrophage	macrophage	NN
cord-032504-tmohg1mj	144	19	[	[	-LRB-
cord-032504-tmohg1mj	144	20	110	110	CD
cord-032504-tmohg1mj	144	21	,	,	,
cord-032504-tmohg1mj	144	22	111	111	CD
cord-032504-tmohg1mj	144	23	]	]	-RRB-
cord-032504-tmohg1mj	144	24	.	.	.
cord-032504-tmohg1mj	145	1	At	at	IN
cord-032504-tmohg1mj	145	2	least	least	JJS
cord-032504-tmohg1mj	145	3	some	some	DT
cord-032504-tmohg1mj	145	4	of	of	IN
cord-032504-tmohg1mj	145	5	these	these	DT
cord-032504-tmohg1mj	145	6	impairments	impairment	NNS
cord-032504-tmohg1mj	145	7	may	may	MD
cord-032504-tmohg1mj	145	8	be	be	VB
cord-032504-tmohg1mj	145	9	mediated	mediate	VBN
cord-032504-tmohg1mj	145	10	through	through	IN
cord-032504-tmohg1mj	145	11	the	the	DT
cord-032504-tmohg1mj	145	12	effects	effect	NNS
cord-032504-tmohg1mj	145	13	of	of	IN
cord-032504-tmohg1mj	145	14	the	the	DT
cord-032504-tmohg1mj	145	15	HIVrelated	HIVrelated	NNP
cord-032504-tmohg1mj	145	16	protein	protein	NN
cord-032504-tmohg1mj	145	17	transactivator	transactivator	NN
cord-032504-tmohg1mj	145	18	of	of	IN
cord-032504-tmohg1mj	145	19	transcription	transcription	NN
cord-032504-tmohg1mj	145	20	(	(	-LRB-
cord-032504-tmohg1mj	145	21	Tat	tat	NN
cord-032504-tmohg1mj	145	22	)	)	-RRB-
cord-032504-tmohg1mj	145	23	[	[	-LRB-
cord-032504-tmohg1mj	145	24	112	112	CD
cord-032504-tmohg1mj	145	25	]	]	-RRB-
cord-032504-tmohg1mj	145	26	.	.	.
cord-032504-tmohg1mj	146	1	Another	another	DT
cord-032504-tmohg1mj	146	2	HIV	HIV	NNP
cord-032504-tmohg1mj	146	3	protein	protein	NN
cord-032504-tmohg1mj	146	4	,	,	,
cord-032504-tmohg1mj	146	5	Vpr	Vpr	NNP
cord-032504-tmohg1mj	146	6	,	,	,
cord-032504-tmohg1mj	146	7	has	have	VBZ
cord-032504-tmohg1mj	146	8	also	also	RB
cord-032504-tmohg1mj	146	9	been	be	VBN
cord-032504-tmohg1mj	146	10	shown	show	VBN
cord-032504-tmohg1mj	146	11	to	to	TO
cord-032504-tmohg1mj	146	12	perturb	perturb	VB
cord-032504-tmohg1mj	146	13	phagolysosomal	phagolysosomal	JJ
cord-032504-tmohg1mj	146	14	maturation	maturation	NN
cord-032504-tmohg1mj	146	15	by	by	IN
cord-032504-tmohg1mj	146	16	altering	alter	VBG
cord-032504-tmohg1mj	146	17	microtubule	microtubule	NN
cord-032504-tmohg1mj	146	18	-	-	HYPH
cord-032504-tmohg1mj	146	19	dependent	dependent	JJ
cord-032504-tmohg1mj	146	20	trafficking	trafficking	NN
cord-032504-tmohg1mj	146	21	within	within	IN
cord-032504-tmohg1mj	146	22	macrophages	macrophage	NNS
cord-032504-tmohg1mj	146	23	[	[	-LRB-
cord-032504-tmohg1mj	146	24	113	113	CD
cord-032504-tmohg1mj	146	25	]	]	-RRB-
cord-032504-tmohg1mj	146	26	.	.	.
cord-032504-tmohg1mj	147	1	In	in	IN
cord-032504-tmohg1mj	147	2	addition	addition	NN
cord-032504-tmohg1mj	147	3	,	,	,
cord-032504-tmohg1mj	147	4	HIV	HIV	NNP
cord-032504-tmohg1mj	147	5	has	have	VBZ
cord-032504-tmohg1mj	147	6	been	be	VBN
cord-032504-tmohg1mj	147	7	shown	show	VBN
cord-032504-tmohg1mj	147	8	to	to	TO
cord-032504-tmohg1mj	147	9	co	co	VB
cord-032504-tmohg1mj	147	10	-	-	VB
cord-032504-tmohg1mj	147	11	opt	opt	VB
cord-032504-tmohg1mj	147	12	the	the	DT
cord-032504-tmohg1mj	147	13	Rag	rag	NN
cord-032504-tmohg1mj	147	14	GTPases	gtpase	NNS
cord-032504-tmohg1mj	147	15	,	,	,
cord-032504-tmohg1mj	147	16	resulting	result	VBG
cord-032504-tmohg1mj	147	17	in	in	IN
cord-032504-tmohg1mj	147	18	further	further	JJ
cord-032504-tmohg1mj	147	19	disruption	disruption	NN
cord-032504-tmohg1mj	147	20	of	of	IN
cord-032504-tmohg1mj	147	21	endosomal	endosomal	NNP
cord-032504-tmohg1mj	147	22	trafficking	traffic	VBG
cord-032504-tmohg1mj	147	23	[	[	-LRB-
cord-032504-tmohg1mj	147	24	114	114	CD
cord-032504-tmohg1mj	147	25	]	]	-RRB-
cord-032504-tmohg1mj	147	26	.	.	.
cord-032504-tmohg1mj	148	1	This	this	DT
cord-032504-tmohg1mj	148	2	disruption	disruption	NN
cord-032504-tmohg1mj	148	3	may	may	MD
cord-032504-tmohg1mj	148	4	facilitate	facilitate	VB
cord-032504-tmohg1mj	148	5	HIV	HIV	NNP
cord-032504-tmohg1mj	148	6	replication	replication	NN
cord-032504-tmohg1mj	148	7	and	and	CC
cord-032504-tmohg1mj	148	8	simultaneously	simultaneously	RB
cord-032504-tmohg1mj	148	9	assist	assist	VB
cord-032504-tmohg1mj	148	10	Mtb	Mtb	NNP
cord-032504-tmohg1mj	148	11	evasion	evasion	NN
cord-032504-tmohg1mj	148	12	of	of	IN
cord-032504-tmohg1mj	148	13	lysosomal	lysosomal	JJ
cord-032504-tmohg1mj	148	14	fusion	fusion	NN
cord-032504-tmohg1mj	148	15	and	and	CC
cord-032504-tmohg1mj	148	16	killing	killing	NN
cord-032504-tmohg1mj	148	17	.	.	.
cord-032504-tmohg1mj	149	1	IL-10	IL-10	NNP
cord-032504-tmohg1mj	149	2	has	have	VBZ
cord-032504-tmohg1mj	149	3	also	also	RB
cord-032504-tmohg1mj	149	4	been	be	VBN
cord-032504-tmohg1mj	149	5	shown	show	VBN
cord-032504-tmohg1mj	149	6	to	to	TO
cord-032504-tmohg1mj	149	7	dysregulate	dysregulate	VB
cord-032504-tmohg1mj	149	8	the	the	DT
cord-032504-tmohg1mj	149	9	response	response	NN
cord-032504-tmohg1mj	149	10	to	to	IN
cord-032504-tmohg1mj	149	11	Mtb	Mtb	NNP
cord-032504-tmohg1mj	149	12	in	in	IN
cord-032504-tmohg1mj	149	13	the	the	DT
cord-032504-tmohg1mj	149	14	setting	setting	NN
cord-032504-tmohg1mj	149	15	of	of	IN
cord-032504-tmohg1mj	149	16	HIV	HIV	NNP
cord-032504-tmohg1mj	149	17	,	,	,
cord-032504-tmohg1mj	149	18	at	at	IN
cord-032504-tmohg1mj	149	19	least	least	JJS
cord-032504-tmohg1mj	149	20	in	in	IN
cord-032504-tmohg1mj	149	21	part	part	NN
cord-032504-tmohg1mj	149	22	by	by	IN
cord-032504-tmohg1mj	149	23	impairing	impair	VBG
cord-032504-tmohg1mj	149	24	phagosome	phagosome	NN
cord-032504-tmohg1mj	149	25	maturation	maturation	NN
cord-032504-tmohg1mj	149	26	[	[	-LRB-
cord-032504-tmohg1mj	149	27	115	115	CD
cord-032504-tmohg1mj	149	28	,	,	,
cord-032504-tmohg1mj	149	29	116	116	CD
cord-032504-tmohg1mj	149	30	]	]	-RRB-
cord-032504-tmohg1mj	149	31	.	.	.
cord-032504-tmohg1mj	150	1	However	however	RB
cord-032504-tmohg1mj	150	2	,	,	,
cord-032504-tmohg1mj	150	3	in	in	IN
cord-032504-tmohg1mj	150	4	one	one	CD
cord-032504-tmohg1mj	150	5	study	study	NN
cord-032504-tmohg1mj	150	6	of	of	IN
cord-032504-tmohg1mj	150	7	alveolar	alveolar	JJ
cord-032504-tmohg1mj	150	8	macrophages	macrophage	NNS
cord-032504-tmohg1mj	150	9	from	from	IN
cord-032504-tmohg1mj	150	10	humans	human	NNS
cord-032504-tmohg1mj	150	11	with	with	IN
cord-032504-tmohg1mj	150	12	active	active	JJ
cord-032504-tmohg1mj	150	13	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	150	14	disease	disease	NN
cord-032504-tmohg1mj	150	15	,	,	,
cord-032504-tmohg1mj	150	16	phagolysosomal	phagolysosomal	JJ
cord-032504-tmohg1mj	150	17	acidification	acidification	NN
cord-032504-tmohg1mj	150	18	was	be	VBD
cord-032504-tmohg1mj	150	19	equally	equally	RB
cord-032504-tmohg1mj	150	20	disrupted	disrupt	VBN
cord-032504-tmohg1mj	150	21	among	among	IN
cord-032504-tmohg1mj	150	22	those	those	DT
cord-032504-tmohg1mj	150	23	with	with	IN
cord-032504-tmohg1mj	150	24	and	and	CC
cord-032504-tmohg1mj	150	25	without	without	IN
cord-032504-tmohg1mj	150	26	HIV	HIV	NNP
cord-032504-tmohg1mj	150	27	,	,	,
cord-032504-tmohg1mj	150	28	highlighting	highlight	VBG
cord-032504-tmohg1mj	150	29	existing	exist	VBG
cord-032504-tmohg1mj	150	30	uncertainties	uncertainty	NNS
cord-032504-tmohg1mj	150	31	about	about	IN
cord-032504-tmohg1mj	150	32	the	the	DT
cord-032504-tmohg1mj	150	33	impacts	impact	NNS
cord-032504-tmohg1mj	150	34	of	of	IN
cord-032504-tmohg1mj	150	35	Mtb	Mtb	NNP
cord-032504-tmohg1mj	150	36	and	and	CC
cord-032504-tmohg1mj	150	37	HIV	HIV	NNP
cord-032504-tmohg1mj	150	38	on	on	IN
cord-032504-tmohg1mj	150	39	alveolar	alveolar	JJ
cord-032504-tmohg1mj	150	40	macrophage	macrophage	NN
cord-032504-tmohg1mj	150	41	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	150	42	[	[	-LRB-
cord-032504-tmohg1mj	150	43	117	117	CD
cord-032504-tmohg1mj	150	44	]	]	-RRB-
cord-032504-tmohg1mj	150	45	.	.	.
cord-032504-tmohg1mj	151	1	Thus	thus	RB
cord-032504-tmohg1mj	151	2	,	,	,
cord-032504-tmohg1mj	151	3	although	although	IN
cord-032504-tmohg1mj	151	4	further	further	JJ
cord-032504-tmohg1mj	151	5	research	research	NN
cord-032504-tmohg1mj	151	6	is	be	VBZ
cord-032504-tmohg1mj	151	7	needed	need	VBN
cord-032504-tmohg1mj	151	8	to	to	TO
cord-032504-tmohg1mj	151	9	define	define	VB
cord-032504-tmohg1mj	151	10	the	the	DT
cord-032504-tmohg1mj	151	11	relevant	relevant	JJ
cord-032504-tmohg1mj	151	12	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	151	13	by	by	IN
cord-032504-tmohg1mj	151	14	which	which	WDT
cord-032504-tmohg1mj	151	15	HIV	HIV	NNP
cord-032504-tmohg1mj	151	16	impairs	impair	VBZ
cord-032504-tmohg1mj	151	17	the	the	DT
cord-032504-tmohg1mj	151	18	phagocytic	phagocytic	JJ
cord-032504-tmohg1mj	151	19	response	response	NN
cord-032504-tmohg1mj	151	20	to	to	IN
cord-032504-tmohg1mj	151	21	Mtb	Mtb	NNP
cord-032504-tmohg1mj	151	22	,	,	,
cord-032504-tmohg1mj	151	23	the	the	DT
cord-032504-tmohg1mj	151	24	bulk	bulk	NN
cord-032504-tmohg1mj	151	25	of	of	IN
cord-032504-tmohg1mj	151	26	the	the	DT
cord-032504-tmohg1mj	151	27	existing	exist	VBG
cord-032504-tmohg1mj	151	28	data	datum	NNS
cord-032504-tmohg1mj	151	29	suggest	suggest	VBP
cord-032504-tmohg1mj	151	30	that	that	IN
cord-032504-tmohg1mj	151	31	endosomes	endosome	NNS
cord-032504-tmohg1mj	151	32	fail	fail	VBP
cord-032504-tmohg1mj	151	33	to	to	TO
cord-032504-tmohg1mj	151	34	fuse	fuse	VB
cord-032504-tmohg1mj	151	35	with	with	IN
cord-032504-tmohg1mj	151	36	acidified	acidified	JJ
cord-032504-tmohg1mj	151	37	lysosomes	lysosome	NNS
cord-032504-tmohg1mj	151	38	,	,	,
cord-032504-tmohg1mj	151	39	thereby	thereby	RB
cord-032504-tmohg1mj	151	40	promoting	promote	VBG
cord-032504-tmohg1mj	151	41	Mtb	Mtb	NNP
cord-032504-tmohg1mj	151	42	survival	survival	NN
cord-032504-tmohg1mj	151	43	[	[	-LRB-
cord-032504-tmohg1mj	151	44	118	118	CD
cord-032504-tmohg1mj	151	45	]	]	-RRB-
cord-032504-tmohg1mj	151	46	.	.	.
cord-032504-tmohg1mj	152	1	Alveolar	alveolar	NN
cord-032504-tmohg1mj	152	2	macrophage	macrophage	NN
cord-032504-tmohg1mj	152	3	cell	cell	NN
cord-032504-tmohg1mj	152	4	death	death	NN
cord-032504-tmohg1mj	152	5	pathways	pathway	NNS
cord-032504-tmohg1mj	152	6	range	range	VBP
cord-032504-tmohg1mj	152	7	from	from	IN
cord-032504-tmohg1mj	152	8	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	152	9	to	to	IN
cord-032504-tmohg1mj	152	10	autophagy	autophagy	NN
cord-032504-tmohg1mj	152	11	and	and	CC
cord-032504-tmohg1mj	152	12	necrosis	necrosis	NN
cord-032504-tmohg1mj	152	13	.	.	.
cord-032504-tmohg1mj	153	1	Mtb	Mtb	NNP
cord-032504-tmohg1mj	153	2	is	be	VBZ
cord-032504-tmohg1mj	153	3	known	know	VBN
cord-032504-tmohg1mj	153	4	to	to	TO
cord-032504-tmohg1mj	153	5	shift	shift	VB
cord-032504-tmohg1mj	153	6	the	the	DT
cord-032504-tmohg1mj	153	7	balance	balance	NN
cord-032504-tmohg1mj	153	8	toward	toward	IN
cord-032504-tmohg1mj	153	9	necrosis	necrosis	NN
cord-032504-tmohg1mj	153	10	by	by	IN
cord-032504-tmohg1mj	153	11	actively	actively	RB
cord-032504-tmohg1mj	153	12	inhibiting	inhibit	VBG
cord-032504-tmohg1mj	153	13	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	153	14	,	,	,
cord-032504-tmohg1mj	153	15	thereby	thereby	RB
cord-032504-tmohg1mj	153	16	allowing	allow	VBG
cord-032504-tmohg1mj	153	17	the	the	DT
cord-032504-tmohg1mj	153	18	extracellular	extracellular	JJ
cord-032504-tmohg1mj	153	19	release	release	NN
cord-032504-tmohg1mj	153	20	of	of	IN
cord-032504-tmohg1mj	153	21	viable	viable	JJ
cord-032504-tmohg1mj	153	22	mycobacteria	mycobacterium	NNS
cord-032504-tmohg1mj	153	23	from	from	IN
cord-032504-tmohg1mj	153	24	dying	die	VBG
cord-032504-tmohg1mj	153	25	alveolar	alveolar	NN
cord-032504-tmohg1mj	153	26	macrophages	macrophage	NNS
cord-032504-tmohg1mj	153	27	[	[	-LRB-
cord-032504-tmohg1mj	153	28	119	119	CD
cord-032504-tmohg1mj	153	29	,	,	,
cord-032504-tmohg1mj	153	30	120	120	CD
cord-032504-tmohg1mj	153	31	]	]	-RRB-
cord-032504-tmohg1mj	153	32	.	.	.
cord-032504-tmohg1mj	154	1	Similarly	similarly	RB
cord-032504-tmohg1mj	154	2	,	,	,
cord-032504-tmohg1mj	154	3	HIV	HIV	NNP
cord-032504-tmohg1mj	154	4	,	,	,
cord-032504-tmohg1mj	154	5	via	via	IN
cord-032504-tmohg1mj	154	6	the	the	DT
cord-032504-tmohg1mj	154	7	viral	viral	JJ
cord-032504-tmohg1mj	154	8	proteins	protein	NNS
cord-032504-tmohg1mj	154	9	Tat	Tat	NNP
cord-032504-tmohg1mj	154	10	and	and	CC
cord-032504-tmohg1mj	154	11	glycoprotein-120	glycoprotein-120	NN
cord-032504-tmohg1mj	154	12	(	(	-LRB-
cord-032504-tmohg1mj	154	13	gp-120	gp-120	NNP
cord-032504-tmohg1mj	154	14	)	)	-RRB-
cord-032504-tmohg1mj	154	15	,	,	,
cord-032504-tmohg1mj	154	16	stimulates	stimulate	VBZ
cord-032504-tmohg1mj	154	17	the	the	DT
cord-032504-tmohg1mj	154	18	triggering	trigger	VBG
cord-032504-tmohg1mj	154	19	receptor	receptor	NN
cord-032504-tmohg1mj	154	20	expressed	express	VBN
cord-032504-tmohg1mj	154	21	on	on	IN
cord-032504-tmohg1mj	154	22	myeloid	myeloid	JJ
cord-032504-tmohg1mj	154	23	cells-1	cells-1	NNP
cord-032504-tmohg1mj	154	24	(	(	-LRB-
cord-032504-tmohg1mj	154	25	TREM-1	TREM-1	NNP
cord-032504-tmohg1mj	154	26	)	)	-RRB-
cord-032504-tmohg1mj	154	27	,	,	,
cord-032504-tmohg1mj	154	28	thereby	thereby	RB
cord-032504-tmohg1mj	154	29	inhibiting	inhibit	VBG
cord-032504-tmohg1mj	154	30	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	154	31	in	in	IN
cord-032504-tmohg1mj	154	32	a	a	DT
cord-032504-tmohg1mj	154	33	p65-dependent	p65-dependent	CD
cord-032504-tmohg1mj	154	34	manner	manner	NN
cord-032504-tmohg1mj	154	35	[	[	-LRB-
cord-032504-tmohg1mj	154	36	121	121	CD
cord-032504-tmohg1mj	154	37	]	]	-RRB-
cord-032504-tmohg1mj	154	38	.	.	.
cord-032504-tmohg1mj	155	1	HIV	HIV	NNP
cord-032504-tmohg1mj	155	2	may	may	MD
cord-032504-tmohg1mj	155	3	also	also	RB
cord-032504-tmohg1mj	155	4	directly	directly	RB
cord-032504-tmohg1mj	155	5	induce	induce	VB
cord-032504-tmohg1mj	155	6	autophagy	autophagy	NN
cord-032504-tmohg1mj	155	7	through	through	IN
cord-032504-tmohg1mj	155	8	the	the	DT
cord-032504-tmohg1mj	155	9	Nef	Nef	NNP
cord-032504-tmohg1mj	155	10	protein	protein	NN
cord-032504-tmohg1mj	155	11	,	,	,
cord-032504-tmohg1mj	155	12	in	in	IN
cord-032504-tmohg1mj	155	13	order	order	NN
cord-032504-tmohg1mj	155	14	to	to	TO
cord-032504-tmohg1mj	155	15	modulate	modulate	VB
cord-032504-tmohg1mj	155	16	viral	viral	JJ
cord-032504-tmohg1mj	155	17	replication	replication	NN
cord-032504-tmohg1mj	155	18	and	and	CC
cord-032504-tmohg1mj	155	19	survival	survival	NN
cord-032504-tmohg1mj	155	20	,	,	,
cord-032504-tmohg1mj	155	21	albeit	albeit	IN
cord-032504-tmohg1mj	155	22	in	in	IN
cord-032504-tmohg1mj	155	23	a	a	DT
cord-032504-tmohg1mj	155	24	manner	manner	NN
cord-032504-tmohg1mj	155	25	that	that	WDT
cord-032504-tmohg1mj	155	26	may	may	MD
cord-032504-tmohg1mj	155	27	be	be	VB
cord-032504-tmohg1mj	155	28	synergistic	synergistic	JJ
cord-032504-tmohg1mj	155	29	with	with	IN
cord-032504-tmohg1mj	155	30	Mtb	Mtb	NNP
cord-032504-tmohg1mj	155	31	-	-	HYPH
cord-032504-tmohg1mj	155	32	mediated	mediate	VBN
cord-032504-tmohg1mj	155	33	inhibition	inhibition	NN
cord-032504-tmohg1mj	155	34	of	of	IN
cord-032504-tmohg1mj	155	35	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	155	36	[	[	-LRB-
cord-032504-tmohg1mj	155	37	122	122	CD
cord-032504-tmohg1mj	155	38	,	,	,
cord-032504-tmohg1mj	155	39	123	123	CD
cord-032504-tmohg1mj	155	40	]	]	-RRB-
cord-032504-tmohg1mj	155	41	.	.	.
cord-032504-tmohg1mj	156	1	Gp-120	Gp-120	NFP
cord-032504-tmohg1mj	156	2	also	also	RB
cord-032504-tmohg1mj	156	3	impairs	impair	VBZ
cord-032504-tmohg1mj	156	4	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	156	5	-	-	HYPH
cord-032504-tmohg1mj	156	6	associated	associate	VBN
cord-032504-tmohg1mj	156	7	killing	killing	NN
cord-032504-tmohg1mj	156	8	of	of	IN
cord-032504-tmohg1mj	156	9	pneumococcus	pneumococcus	NN
cord-032504-tmohg1mj	156	10	within	within	IN
cord-032504-tmohg1mj	156	11	alveolar	alveolar	JJ
cord-032504-tmohg1mj	156	12	macrophages	macrophage	NNS
cord-032504-tmohg1mj	156	13	,	,	,
cord-032504-tmohg1mj	156	14	indicating	indicate	VBG
cord-032504-tmohg1mj	156	15	that	that	IN
cord-032504-tmohg1mj	156	16	this	this	DT
cord-032504-tmohg1mj	156	17	impairment	impairment	NN
cord-032504-tmohg1mj	156	18	may	may	MD
cord-032504-tmohg1mj	156	19	not	not	RB
cord-032504-tmohg1mj	156	20	be	be	VB
cord-032504-tmohg1mj	156	21	specific	specific	JJ
cord-032504-tmohg1mj	156	22	to	to	IN
cord-032504-tmohg1mj	156	23	Mtb	Mtb	NNP
cord-032504-tmohg1mj	156	24	[	[	-LRB-
cord-032504-tmohg1mj	156	25	124	124	CD
cord-032504-tmohg1mj	156	26	]	]	-RRB-
cord-032504-tmohg1mj	156	27	.	.	.
cord-032504-tmohg1mj	157	1	Impaired	impaired	JJ
cord-032504-tmohg1mj	157	2	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	157	3	of	of	IN
cord-032504-tmohg1mj	157	4	Mtb	Mtb	NNP
cord-032504-tmohg1mj	157	5	has	have	VBZ
cord-032504-tmohg1mj	157	6	been	be	VBN
cord-032504-tmohg1mj	157	7	tied	tie	VBN
cord-032504-tmohg1mj	157	8	by	by	IN
cord-032504-tmohg1mj	157	9	other	other	JJ
cord-032504-tmohg1mj	157	10	investigators	investigator	NNS
cord-032504-tmohg1mj	157	11	to	to	IN
cord-032504-tmohg1mj	157	12	IL-10	IL-10	NNP
cord-032504-tmohg1mj	157	13	,	,	,
cord-032504-tmohg1mj	157	14	which	which	WDT
cord-032504-tmohg1mj	157	15	is	be	VBZ
cord-032504-tmohg1mj	157	16	increased	increase	VBN
cord-032504-tmohg1mj	157	17	in	in	IN
cord-032504-tmohg1mj	157	18	the	the	DT
cord-032504-tmohg1mj	157	19	bronchoalveolar	bronchoalveolar	NNP
cord-032504-tmohg1mj	157	20	lavage	lavage	NN
cord-032504-tmohg1mj	157	21	fluid	fluid	NN
cord-032504-tmohg1mj	157	22	of	of	IN
cord-032504-tmohg1mj	157	23	people	people	NNS
cord-032504-tmohg1mj	157	24	with	with	IN
cord-032504-tmohg1mj	157	25	HIV	HIV	NNP
cord-032504-tmohg1mj	157	26	[	[	-LRB-
cord-032504-tmohg1mj	157	27	125	125	CD
cord-032504-tmohg1mj	157	28	]	]	-RRB-
cord-032504-tmohg1mj	157	29	.	.	.
cord-032504-tmohg1mj	158	1	Additional	additional	JJ
cord-032504-tmohg1mj	158	2	research	research	NN
cord-032504-tmohg1mj	158	3	is	be	VBZ
cord-032504-tmohg1mj	158	4	needed	need	VBN
cord-032504-tmohg1mj	158	5	to	to	TO
cord-032504-tmohg1mj	158	6	further	further	RB
cord-032504-tmohg1mj	158	7	delineate	delineate	VB
cord-032504-tmohg1mj	158	8	the	the	DT
cord-032504-tmohg1mj	158	9	impact	impact	NN
cord-032504-tmohg1mj	158	10	of	of	IN
cord-032504-tmohg1mj	158	11	these	these	DT
cord-032504-tmohg1mj	158	12	shifts	shift	NNS
cord-032504-tmohg1mj	158	13	in	in	IN
cord-032504-tmohg1mj	158	14	cell	cell	NN
cord-032504-tmohg1mj	158	15	death	death	NN
cord-032504-tmohg1mj	158	16	pathways	pathway	NNS
cord-032504-tmohg1mj	158	17	and	and	CC
cord-032504-tmohg1mj	158	18	to	to	TO
cord-032504-tmohg1mj	158	19	identify	identify	VB
cord-032504-tmohg1mj	158	20	whether	whether	IN
cord-032504-tmohg1mj	158	21	there	there	EX
cord-032504-tmohg1mj	158	22	are	be	VBP
cord-032504-tmohg1mj	158	23	therapeutic	therapeutic	JJ
cord-032504-tmohg1mj	158	24	opportunities	opportunity	NNS
cord-032504-tmohg1mj	158	25	to	to	TO
cord-032504-tmohg1mj	158	26	improve	improve	VB
cord-032504-tmohg1mj	158	27	Mtb	Mtb	NNP
cord-032504-tmohg1mj	158	28	control	control	NN
cord-032504-tmohg1mj	158	29	in	in	IN
cord-032504-tmohg1mj	158	30	patients	patient	NNS
cord-032504-tmohg1mj	158	31	with	with	IN
cord-032504-tmohg1mj	158	32	and	and	CC
cord-032504-tmohg1mj	158	33	without	without	IN
cord-032504-tmohg1mj	158	34	HIV	HIV	NNP
cord-032504-tmohg1mj	158	35	.	.	.
cord-032504-tmohg1mj	159	1	One	one	CD
cord-032504-tmohg1mj	159	2	promising	promise	VBG
cord-032504-tmohg1mj	159	3	recent	recent	JJ
cord-032504-tmohg1mj	159	4	report	report	NN
cord-032504-tmohg1mj	159	5	found	find	VBD
cord-032504-tmohg1mj	159	6	that	that	IN
cord-032504-tmohg1mj	159	7	all	all	RB
cord-032504-tmohg1mj	159	8	-	-	HYPH
cord-032504-tmohg1mj	159	9	trans	trans	NNP
cord-032504-tmohg1mj	159	10	retinoic	retinoic	JJ
cord-032504-tmohg1mj	159	11	acid	acid	NN
cord-032504-tmohg1mj	159	12	was	be	VBD
cord-032504-tmohg1mj	159	13	able	able	JJ
cord-032504-tmohg1mj	159	14	to	to	TO
cord-032504-tmohg1mj	159	15	promote	promote	VB
cord-032504-tmohg1mj	159	16	autophagy	autophagy	NN
cord-032504-tmohg1mj	159	17	of	of	IN
cord-032504-tmohg1mj	159	18	human	human	JJ
cord-032504-tmohg1mj	159	19	alveolar	alveolar	NN
cord-032504-tmohg1mj	159	20	macrophages	macrophage	NNS
cord-032504-tmohg1mj	159	21	in	in	IN
cord-032504-tmohg1mj	159	22	the	the	DT
cord-032504-tmohg1mj	159	23	setting	setting	NN
cord-032504-tmohg1mj	159	24	of	of	IN
cord-032504-tmohg1mj	159	25	Mtb	Mtb	NNP
cord-032504-tmohg1mj	159	26	infection	infection	NN
cord-032504-tmohg1mj	159	27	[	[	-LRB-
cord-032504-tmohg1mj	159	28	126	126	CD
cord-032504-tmohg1mj	159	29	]	]	-RRB-
cord-032504-tmohg1mj	159	30	.	.	.
cord-032504-tmohg1mj	160	1	The	the	DT
cord-032504-tmohg1mj	160	2	final	final	JJ
cord-032504-tmohg1mj	160	3	step	step	NN
cord-032504-tmohg1mj	160	4	required	require	VBN
cord-032504-tmohg1mj	160	5	for	for	IN
cord-032504-tmohg1mj	160	6	establishment	establishment	NN
cord-032504-tmohg1mj	160	7	of	of	IN
cord-032504-tmohg1mj	160	8	the	the	DT
cord-032504-tmohg1mj	160	9	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	160	10	set	set	NNP
cord-032504-tmohg1mj	160	11	point	point	NN
cord-032504-tmohg1mj	160	12	is	be	VBZ
cord-032504-tmohg1mj	160	13	activation	activation	NN
cord-032504-tmohg1mj	160	14	of	of	IN
cord-032504-tmohg1mj	160	15	the	the	DT
cord-032504-tmohg1mj	160	16	adaptive	adaptive	JJ
cord-032504-tmohg1mj	160	17	arm	arm	NN
cord-032504-tmohg1mj	160	18	of	of	IN
cord-032504-tmohg1mj	160	19	the	the	DT
cord-032504-tmohg1mj	160	20	immune	immune	JJ
cord-032504-tmohg1mj	160	21	system	system	NN
cord-032504-tmohg1mj	160	22	(	(	-LRB-
cord-032504-tmohg1mj	160	23	Fig	Fig	NNP
cord-032504-tmohg1mj	160	24	.	.	.
cord-032504-tmohg1mj	160	25	3	3	CD
cord-032504-tmohg1mj	160	26	)	)	-RRB-
cord-032504-tmohg1mj	160	27	.	.	.
cord-032504-tmohg1mj	161	1	Mtb	Mtb	NNP
cord-032504-tmohg1mj	161	2	has	have	VBZ
cord-032504-tmohg1mj	161	3	been	be	VBN
cord-032504-tmohg1mj	161	4	shown	show	VBN
cord-032504-tmohg1mj	161	5	to	to	TO
cord-032504-tmohg1mj	161	6	delay	delay	VB
cord-032504-tmohg1mj	161	7	the	the	DT
cord-032504-tmohg1mj	161	8	activation	activation	NN
cord-032504-tmohg1mj	161	9	of	of	IN
cord-032504-tmohg1mj	161	10	adaptive	adaptive	JJ
cord-032504-tmohg1mj	161	11	immunity	immunity	NN
cord-032504-tmohg1mj	161	12	in	in	IN
cord-032504-tmohg1mj	161	13	mice	mouse	NNS
cord-032504-tmohg1mj	161	14	by	by	IN
cord-032504-tmohg1mj	161	15	slowing	slow	VBG
cord-032504-tmohg1mj	161	16	bacterial	bacterial	JJ
cord-032504-tmohg1mj	161	17	transport	transport	NN
cord-032504-tmohg1mj	161	18	to	to	IN
cord-032504-tmohg1mj	161	19	local	local	JJ
cord-032504-tmohg1mj	161	20	lymph	lymph	NN
cord-032504-tmohg1mj	161	21	nodes	node	NNS
cord-032504-tmohg1mj	161	22	[	[	-LRB-
cord-032504-tmohg1mj	161	23	46	46	CD
cord-032504-tmohg1mj	161	24	]	]	-RRB-
cord-032504-tmohg1mj	161	25	.	.	.
cord-032504-tmohg1mj	162	1	This	this	DT
cord-032504-tmohg1mj	162	2	delay	delay	NN
cord-032504-tmohg1mj	162	3	allows	allow	VBZ
cord-032504-tmohg1mj	162	4	for	for	IN
cord-032504-tmohg1mj	162	5	a	a	DT
cord-032504-tmohg1mj	162	6	prolonged	prolonged	JJ
cord-032504-tmohg1mj	162	7	period	period	NN
cord-032504-tmohg1mj	162	8	of	of	IN
cord-032504-tmohg1mj	162	9	unchecked	unchecked	JJ
cord-032504-tmohg1mj	162	10	bacterial	bacterial	JJ
cord-032504-tmohg1mj	162	11	growth	growth	NN
cord-032504-tmohg1mj	162	12	within	within	IN
cord-032504-tmohg1mj	162	13	the	the	DT
cord-032504-tmohg1mj	162	14	lungs	lung	NNS
cord-032504-tmohg1mj	162	15	,	,	,
cord-032504-tmohg1mj	162	16	with	with	IN
cord-032504-tmohg1mj	162	17	a	a	DT
cord-032504-tmohg1mj	162	18	10,000	10,000	CD
cord-032504-tmohg1mj	162	19	-	-	SYM
cord-032504-tmohg1mj	162	20	100,000-fold	100,000-fold	CD
cord-032504-tmohg1mj	162	21	expansion	expansion	NN
cord-032504-tmohg1mj	162	22	of	of	IN
cord-032504-tmohg1mj	162	23	the	the	DT
cord-032504-tmohg1mj	162	24	Mtb	Mtb	NNP
cord-032504-tmohg1mj	162	25	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	162	26	population	population	NN
cord-032504-tmohg1mj	162	27	during	during	IN
cord-032504-tmohg1mj	162	28	this	this	DT
cord-032504-tmohg1mj	162	29	time	time	NN
cord-032504-tmohg1mj	162	30	.	.	.
cord-032504-tmohg1mj	163	1	At	at	RB
cord-032504-tmohg1mj	163	2	least	least	RBS
cord-032504-tmohg1mj	163	3	one	one	CD
cord-032504-tmohg1mj	163	4	driver	driver	NN
cord-032504-tmohg1mj	163	5	of	of	IN
cord-032504-tmohg1mj	163	6	this	this	DT
cord-032504-tmohg1mj	163	7	delay	delay	NN
cord-032504-tmohg1mj	163	8	is	be	VBZ
cord-032504-tmohg1mj	163	9	Mtb	Mtb	NNP
cord-032504-tmohg1mj	163	10	-	-	HYPH
cord-032504-tmohg1mj	163	11	mediated	mediate	VBN
cord-032504-tmohg1mj	163	12	inhibition	inhibition	NN
cord-032504-tmohg1mj	163	13	of	of	IN
cord-032504-tmohg1mj	163	14	MHC	MHC	NNP
cord-032504-tmohg1mj	163	15	class	class	NN
cord-032504-tmohg1mj	163	16	II	II	NNP
cord-032504-tmohg1mj	163	17	antigen	antigen	NN
cord-032504-tmohg1mj	163	18	presentation	presentation	NN
cord-032504-tmohg1mj	163	19	by	by	IN
cord-032504-tmohg1mj	163	20	dendritic	dendritic	JJ
cord-032504-tmohg1mj	163	21	[	[	-LRB-
cord-032504-tmohg1mj	163	22	127	127	CD
cord-032504-tmohg1mj	163	23	]	]	-RRB-
cord-032504-tmohg1mj	163	24	.	.	.
cord-032504-tmohg1mj	164	1	Mtb	Mtb	NNP
cord-032504-tmohg1mj	164	2	also	also	RB
cord-032504-tmohg1mj	164	3	manipulates	manipulate	VBZ
cord-032504-tmohg1mj	164	4	antigen	antigen	NN
cord-032504-tmohg1mj	164	5	presentation	presentation	NN
cord-032504-tmohg1mj	164	6	by	by	IN
cord-032504-tmohg1mj	164	7	diverting	divert	VBG
cord-032504-tmohg1mj	164	8	bacterial	bacterial	JJ
cord-032504-tmohg1mj	164	9	proteins	protein	NNS
cord-032504-tmohg1mj	164	10	through	through	IN
cord-032504-tmohg1mj	164	11	a	a	DT
cord-032504-tmohg1mj	164	12	vesicular	vesicular	JJ
cord-032504-tmohg1mj	164	13	export	export	NN
cord-032504-tmohg1mj	164	14	pathway	pathway	NN
cord-032504-tmohg1mj	164	15	,	,	,
cord-032504-tmohg1mj	164	16	away	away	RB
cord-032504-tmohg1mj	164	17	from	from	IN
cord-032504-tmohg1mj	164	18	MHC	MHC	NNP
cord-032504-tmohg1mj	164	19	class	class	NN
cord-032504-tmohg1mj	164	20	II	II	NNP
cord-032504-tmohg1mj	164	21	presentation	presentation	NN
cord-032504-tmohg1mj	164	22	.	.	.
cord-032504-tmohg1mj	165	1	In	in	IN
cord-032504-tmohg1mj	165	2	the	the	DT
cord-032504-tmohg1mj	165	3	context	context	NN
cord-032504-tmohg1mj	165	4	of	of	IN
cord-032504-tmohg1mj	165	5	HIV	HIV	NNP
cord-032504-tmohg1mj	165	6	,	,	,
cord-032504-tmohg1mj	165	7	the	the	DT
cord-032504-tmohg1mj	165	8	viral	viral	JJ
cord-032504-tmohg1mj	165	9	protein	protein	NN
cord-032504-tmohg1mj	165	10	Nef	Nef	NNP
cord-032504-tmohg1mj	165	11	has	have	VBZ
cord-032504-tmohg1mj	165	12	been	be	VBN
cord-032504-tmohg1mj	165	13	shown	show	VBN
cord-032504-tmohg1mj	165	14	to	to	TO
cord-032504-tmohg1mj	165	15	promote	promote	VB
cord-032504-tmohg1mj	165	16	the	the	DT
cord-032504-tmohg1mj	165	17	expression	expression	NN
cord-032504-tmohg1mj	165	18	of	of	IN
cord-032504-tmohg1mj	165	19	immature	immature	JJ
cord-032504-tmohg1mj	165	20	,	,	,
cord-032504-tmohg1mj	165	21	functionally	functionally	RB
cord-032504-tmohg1mj	165	22	incompetent	incompetent	JJ
cord-032504-tmohg1mj	165	23	MHC	MHC	NNP
cord-032504-tmohg1mj	165	24	class	class	NN
cord-032504-tmohg1mj	165	25	II	II	NNP
cord-032504-tmohg1mj	165	26	complexes	complex	NNS
cord-032504-tmohg1mj	165	27	[	[	-LRB-
cord-032504-tmohg1mj	165	28	128	128	CD
cord-032504-tmohg1mj	165	29	,	,	,
cord-032504-tmohg1mj	165	30	129	129	CD
cord-032504-tmohg1mj	165	31	]	]	-RRB-
cord-032504-tmohg1mj	165	32	.	.	.
cord-032504-tmohg1mj	166	1	Recent	recent	JJ
cord-032504-tmohg1mj	166	2	data	datum	NNS
cord-032504-tmohg1mj	166	3	have	have	VBP
cord-032504-tmohg1mj	166	4	more	more	RBR
cord-032504-tmohg1mj	166	5	directly	directly	RB
cord-032504-tmohg1mj	166	6	linked	link	VBN
cord-032504-tmohg1mj	166	7	these	these	DT
cord-032504-tmohg1mj	166	8	two	two	CD
cord-032504-tmohg1mj	166	9	by	by	IN
cord-032504-tmohg1mj	166	10	demonstrating	demonstrate	VBG
cord-032504-tmohg1mj	166	11	that	that	IN
cord-032504-tmohg1mj	166	12	HIV	HIV	NNP
cord-032504-tmohg1mj	166	13	-	-	HYPH
cord-032504-tmohg1mj	166	14	infected	infect	VBN
cord-032504-tmohg1mj	166	15	dendritic	dendritic	JJ
cord-032504-tmohg1mj	166	16	cells	cell	NNS
cord-032504-tmohg1mj	166	17	have	have	VBP
cord-032504-tmohg1mj	166	18	reduced	reduce	VBN
cord-032504-tmohg1mj	166	19	ability	ability	NN
cord-032504-tmohg1mj	166	20	to	to	TO
cord-032504-tmohg1mj	166	21	upregulate	upregulate	VB
cord-032504-tmohg1mj	166	22	key	key	JJ
cord-032504-tmohg1mj	166	23	costimulatory	costimulatory	NN
cord-032504-tmohg1mj	166	24	molecules	molecule	NNS
cord-032504-tmohg1mj	166	25	critical	critical	JJ
cord-032504-tmohg1mj	166	26	for	for	IN
cord-032504-tmohg1mj	166	27	antigen	antigen	NN
cord-032504-tmohg1mj	166	28	presentation	presentation	NN
cord-032504-tmohg1mj	166	29	(	(	-LRB-
cord-032504-tmohg1mj	166	30	e.g.	e.g.	RB
cord-032504-tmohg1mj	166	31	,	,	,
cord-032504-tmohg1mj	166	32	CD40	CD40	NNP
cord-032504-tmohg1mj	166	33	,	,	,
cord-032504-tmohg1mj	166	34	CD80	CD80	NNP
cord-032504-tmohg1mj	166	35	,	,	,
cord-032504-tmohg1mj	166	36	and	and	CC
cord-032504-tmohg1mj	166	37	CD86	CD86	NNP
cord-032504-tmohg1mj	166	38	)	)	-RRB-
cord-032504-tmohg1mj	166	39	in	in	IN
cord-032504-tmohg1mj	166	40	the	the	DT
cord-032504-tmohg1mj	166	41	presence	presence	NN
cord-032504-tmohg1mj	166	42	of	of	IN
cord-032504-tmohg1mj	166	43	Mtb	Mtb	NNP
cord-032504-tmohg1mj	166	44	infection	infection	NN
cord-032504-tmohg1mj	166	45	[	[	-LRB-
cord-032504-tmohg1mj	166	46	130	130	CD
cord-032504-tmohg1mj	166	47	]	]	-RRB-
cord-032504-tmohg1mj	166	48	.	.	.
cord-032504-tmohg1mj	167	1	All	all	DT
cord-032504-tmohg1mj	167	2	of	of	IN
cord-032504-tmohg1mj	167	3	this	this	DT
cord-032504-tmohg1mj	167	4	would	would	MD
cord-032504-tmohg1mj	167	5	combine	combine	VB
cord-032504-tmohg1mj	167	6	to	to	TO
cord-032504-tmohg1mj	167	7	delay	delay	VB
cord-032504-tmohg1mj	167	8	the	the	DT
cord-032504-tmohg1mj	167	9	onset	onset	NN
cord-032504-tmohg1mj	167	10	of	of	IN
cord-032504-tmohg1mj	167	11	adapative	adapative	JJ
cord-032504-tmohg1mj	167	12	immunity	immunity	NN
cord-032504-tmohg1mj	167	13	and	and	CC
cord-032504-tmohg1mj	167	14	further	further	RB
cord-032504-tmohg1mj	167	15	increase	increase	VB
cord-032504-tmohg1mj	167	16	the	the	DT
cord-032504-tmohg1mj	167	17	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	167	18	set	set	NN
cord-032504-tmohg1mj	167	19	point	point	NN
cord-032504-tmohg1mj	167	20	.	.	.
cord-032504-tmohg1mj	168	1	As	as	IN
cord-032504-tmohg1mj	168	2	should	should	MD
cord-032504-tmohg1mj	168	3	be	be	VB
cord-032504-tmohg1mj	168	4	clear	clear	JJ
cord-032504-tmohg1mj	168	5	from	from	IN
cord-032504-tmohg1mj	168	6	the	the	DT
cord-032504-tmohg1mj	168	7	preceding	precede	VBG
cord-032504-tmohg1mj	168	8	sections	section	NNS
cord-032504-tmohg1mj	168	9	,	,	,
cord-032504-tmohg1mj	168	10	studies	study	NNS
cord-032504-tmohg1mj	168	11	detailing	detail	VBG
cord-032504-tmohg1mj	168	12	the	the	DT
cord-032504-tmohg1mj	168	13	effects	effect	NNS
cord-032504-tmohg1mj	168	14	of	of	IN
cord-032504-tmohg1mj	168	15	Mtb	Mtb	NNP
cord-032504-tmohg1mj	168	16	and	and	CC
cord-032504-tmohg1mj	168	17	HIV	HIV	NNP
cord-032504-tmohg1mj	168	18	on	on	IN
cord-032504-tmohg1mj	168	19	the	the	DT
cord-032504-tmohg1mj	168	20	immune	immune	JJ
cord-032504-tmohg1mj	168	21	responses	response	NNS
cord-032504-tmohg1mj	168	22	within	within	IN
cord-032504-tmohg1mj	168	23	the	the	DT
cord-032504-tmohg1mj	168	24	alveolar	alveolar	JJ
cord-032504-tmohg1mj	168	25	space	space	NN
cord-032504-tmohg1mj	168	26	have	have	VBP
cord-032504-tmohg1mj	168	27	found	find	VBN
cord-032504-tmohg1mj	168	28	an	an	DT
cord-032504-tmohg1mj	168	29	abundance	abundance	NN
cord-032504-tmohg1mj	168	30	of	of	IN
cord-032504-tmohg1mj	168	31	affected	affected	JJ
cord-032504-tmohg1mj	168	32	cytokines	cytokine	NNS
cord-032504-tmohg1mj	168	33	,	,	,
cord-032504-tmohg1mj	168	34	pathways	pathway	NNS
cord-032504-tmohg1mj	168	35	,	,	,
cord-032504-tmohg1mj	168	36	and	and	CC
cord-032504-tmohg1mj	168	37	response	response	NN
cord-032504-tmohg1mj	168	38	elements	element	NNS
cord-032504-tmohg1mj	168	39	.	.	.
cord-032504-tmohg1mj	169	1	Although	although	IN
cord-032504-tmohg1mj	169	2	much	much	JJ
cord-032504-tmohg1mj	169	3	of	of	IN
cord-032504-tmohg1mj	169	4	the	the	DT
cord-032504-tmohg1mj	169	5	available	available	JJ
cord-032504-tmohg1mj	169	6	data	data	NN
cord-032504-tmohg1mj	169	7	suggests	suggest	VBZ
cord-032504-tmohg1mj	169	8	ways	way	NNS
cord-032504-tmohg1mj	169	9	in	in	IN
cord-032504-tmohg1mj	169	10	which	which	WDT
cord-032504-tmohg1mj	169	11	Mtb	Mtb	NNP
cord-032504-tmohg1mj	169	12	and	and	CC
cord-032504-tmohg1mj	169	13	HIV	HIV	NNP
cord-032504-tmohg1mj	169	14	each	each	DT
cord-032504-tmohg1mj	169	15	make	make	VBP
cord-032504-tmohg1mj	169	16	it	-PRON-	PRP
cord-032504-tmohg1mj	169	17	more	more	RBR
cord-032504-tmohg1mj	169	18	likely	likely	JJ
cord-032504-tmohg1mj	169	19	for	for	IN
cord-032504-tmohg1mj	169	20	the	the	DT
cord-032504-tmohg1mj	169	21	other	other	JJ
cord-032504-tmohg1mj	169	22	to	to	TO
cord-032504-tmohg1mj	169	23	gain	gain	VB
cord-032504-tmohg1mj	169	24	ground	ground	NN
cord-032504-tmohg1mj	169	25	within	within	IN
cord-032504-tmohg1mj	169	26	an	an	DT
cord-032504-tmohg1mj	169	27	individual	individual	NN
cord-032504-tmohg1mj	169	28	's	's	POS
cord-032504-tmohg1mj	169	29	lungs	lung	NNS
cord-032504-tmohg1mj	169	30	,	,	,
cord-032504-tmohg1mj	169	31	the	the	DT
cord-032504-tmohg1mj	169	32	myriad	myriad	NN
cord-032504-tmohg1mj	169	33	as	as	IN
cord-032504-tmohg1mj	169	34	-	-	HYPH
cord-032504-tmohg1mj	169	35	yet	yet	RB
cord-032504-tmohg1mj	169	36	-	-	HYPH
cord-032504-tmohg1mj	169	37	unstudied	unstudied	JJ
cord-032504-tmohg1mj	169	38	pathways	pathway	NNS
cord-032504-tmohg1mj	169	39	leave	leave	VBP
cord-032504-tmohg1mj	169	40	open	open	JJ
cord-032504-tmohg1mj	169	41	the	the	DT
cord-032504-tmohg1mj	169	42	distinct	distinct	JJ
cord-032504-tmohg1mj	169	43	possibility	possibility	NN
cord-032504-tmohg1mj	169	44	that	that	IN
cord-032504-tmohg1mj	169	45	some	some	DT
cord-032504-tmohg1mj	169	46	of	of	IN
cord-032504-tmohg1mj	169	47	their	-PRON-	PRP$
cord-032504-tmohg1mj	169	48	particular	particular	JJ
cord-032504-tmohg1mj	169	49	effects	effect	NNS
cord-032504-tmohg1mj	169	50	may	may	MD
cord-032504-tmohg1mj	169	51	cumulatively	cumulatively	RB
cord-032504-tmohg1mj	169	52	cancel	cancel	VB
cord-032504-tmohg1mj	169	53	out	out	RP
cord-032504-tmohg1mj	169	54	those	those	DT
cord-032504-tmohg1mj	169	55	of	of	IN
cord-032504-tmohg1mj	169	56	the	the	DT
cord-032504-tmohg1mj	169	57	other	other	JJ
cord-032504-tmohg1mj	169	58	pathogen	pathogen	NN
cord-032504-tmohg1mj	169	59	.	.	.
cord-032504-tmohg1mj	170	1	It	-PRON-	PRP
cord-032504-tmohg1mj	170	2	is	be	VBZ
cord-032504-tmohg1mj	170	3	in	in	IN
cord-032504-tmohg1mj	170	4	this	this	DT
cord-032504-tmohg1mj	170	5	key	key	JJ
cord-032504-tmohg1mj	170	6	domain	domain	NN
cord-032504-tmohg1mj	170	7	that	that	WDT
cord-032504-tmohg1mj	170	8	we	-PRON-	PRP
cord-032504-tmohg1mj	170	9	believe	believe	VBP
cord-032504-tmohg1mj	170	10	the	the	DT
cord-032504-tmohg1mj	170	11	concept	concept	NN
cord-032504-tmohg1mj	170	12	of	of	IN
cord-032504-tmohg1mj	170	13	a	a	DT
cord-032504-tmohg1mj	170	14	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	170	15	set	set	NN
cord-032504-tmohg1mj	170	16	point	point	NN
cord-032504-tmohg1mj	170	17	most	most	RBS
cord-032504-tmohg1mj	170	18	clearly	clearly	RB
cord-032504-tmohg1mj	170	19	demonstrates	demonstrate	VBZ
cord-032504-tmohg1mj	170	20	its	-PRON-	PRP$
cord-032504-tmohg1mj	170	21	worth	worth	NN
cord-032504-tmohg1mj	170	22	.	.	.
cord-032504-tmohg1mj	171	1	Because	because	IN
cord-032504-tmohg1mj	171	2	the	the	DT
cord-032504-tmohg1mj	171	3	set	set	NN
cord-032504-tmohg1mj	171	4	point	point	NN
cord-032504-tmohg1mj	171	5	relates	relate	VBZ
cord-032504-tmohg1mj	171	6	to	to	IN
cord-032504-tmohg1mj	171	7	the	the	DT
cord-032504-tmohg1mj	171	8	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	171	9	burden	burden	NN
cord-032504-tmohg1mj	171	10	at	at	IN
cord-032504-tmohg1mj	171	11	the	the	DT
cord-032504-tmohg1mj	171	12	moment	moment	NN
cord-032504-tmohg1mj	171	13	in	in	IN
cord-032504-tmohg1mj	171	14	which	which	WDT
cord-032504-tmohg1mj	171	15	the	the	DT
cord-032504-tmohg1mj	171	16	adaptive	adaptive	JJ
cord-032504-tmohg1mj	171	17	immune	immune	JJ
cord-032504-tmohg1mj	171	18	system	system	NN
cord-032504-tmohg1mj	171	19	activates	activate	VBZ
cord-032504-tmohg1mj	171	20	,	,	,
cord-032504-tmohg1mj	171	21	it	-PRON-	PRP
cord-032504-tmohg1mj	171	22	offers	offer	VBZ
cord-032504-tmohg1mj	171	23	a	a	DT
cord-032504-tmohg1mj	171	24	clinically	clinically	RB
cord-032504-tmohg1mj	171	25	relevant	relevant	JJ
cord-032504-tmohg1mj	171	26	marker	marker	NN
cord-032504-tmohg1mj	171	27	that	that	WDT
cord-032504-tmohg1mj	171	28	synthesizes	synthesize	VBZ
cord-032504-tmohg1mj	171	29	the	the	DT
cord-032504-tmohg1mj	171	30	various	various	JJ
cord-032504-tmohg1mj	171	31	effects	effect	NNS
cord-032504-tmohg1mj	171	32	of	of	IN
cord-032504-tmohg1mj	171	33	coinfections	coinfection	NNS
cord-032504-tmohg1mj	171	34	,	,	,
cord-032504-tmohg1mj	171	35	comorbidities	comorbiditie	NNS
cord-032504-tmohg1mj	171	36	,	,	,
cord-032504-tmohg1mj	171	37	and	and	CC
cord-032504-tmohg1mj	171	38	therapeutics	therapeutic	NNS
cord-032504-tmohg1mj	171	39	.	.	.
cord-032504-tmohg1mj	172	1	As	as	IN
cord-032504-tmohg1mj	172	2	a	a	DT
cord-032504-tmohg1mj	172	3	research	research	NN
cord-032504-tmohg1mj	172	4	tool	tool	NN
cord-032504-tmohg1mj	172	5	,	,	,
cord-032504-tmohg1mj	172	6	then	then	RB
cord-032504-tmohg1mj	172	7	,	,	,
cord-032504-tmohg1mj	172	8	it	-PRON-	PRP
cord-032504-tmohg1mj	172	9	will	will	MD
cord-032504-tmohg1mj	172	10	help	help	VB
cord-032504-tmohg1mj	172	11	us	-PRON-	PRP
cord-032504-tmohg1mj	172	12	understand	understand	VB
cord-032504-tmohg1mj	172	13	whether	whether	IN
cord-032504-tmohg1mj	172	14	the	the	DT
cord-032504-tmohg1mj	172	15	net	net	JJ
cord-032504-tmohg1mj	172	16	effect	effect	NN
cord-032504-tmohg1mj	172	17	of	of	IN
cord-032504-tmohg1mj	172	18	a	a	DT
cord-032504-tmohg1mj	172	19	given	give	VBN
cord-032504-tmohg1mj	172	20	intervention	intervention	NN
cord-032504-tmohg1mj	172	21	actually	actually	RB
cord-032504-tmohg1mj	172	22	reduces	reduce	VBZ
cord-032504-tmohg1mj	172	23	the	the	DT
cord-032504-tmohg1mj	172	24	overall	overall	JJ
cord-032504-tmohg1mj	172	25	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	172	26	burden	burden	NN
cord-032504-tmohg1mj	172	27	,	,	,
cord-032504-tmohg1mj	172	28	as	as	IN
cord-032504-tmohg1mj	172	29	opposed	oppose	VBN
cord-032504-tmohg1mj	172	30	to	to	TO
cord-032504-tmohg1mj	172	31	fruitfully	fruitfully	RB
cord-032504-tmohg1mj	172	32	manipulating	manipulate	VBG
cord-032504-tmohg1mj	172	33	a	a	DT
cord-032504-tmohg1mj	172	34	single	single	JJ
cord-032504-tmohg1mj	172	35	pathway	pathway	NN
cord-032504-tmohg1mj	172	36	(	(	-LRB-
cord-032504-tmohg1mj	172	37	with	with	IN
cord-032504-tmohg1mj	172	38	the	the	DT
cord-032504-tmohg1mj	172	39	knowledge	knowledge	NN
cord-032504-tmohg1mj	172	40	that	that	WDT
cord-032504-tmohg1mj	172	41	doing	do	VBG
cord-032504-tmohg1mj	172	42	so	so	RB
cord-032504-tmohg1mj	172	43	may	may	MD
cord-032504-tmohg1mj	172	44	have	have	VB
cord-032504-tmohg1mj	172	45	deleterious	deleterious	JJ
cord-032504-tmohg1mj	172	46	effects	effect	NNS
cord-032504-tmohg1mj	172	47	on	on	IN
cord-032504-tmohg1mj	172	48	others	other	NNS
cord-032504-tmohg1mj	172	49	)	)	-RRB-
cord-032504-tmohg1mj	172	50	.	.	.
cord-032504-tmohg1mj	173	1	Fortunately	fortunately	RB
cord-032504-tmohg1mj	173	2	,	,	,
cord-032504-tmohg1mj	173	3	several	several	JJ
cord-032504-tmohg1mj	173	4	novel	novel	NN
cord-032504-tmohg1mj	173	5	approaches	approach	NNS
cord-032504-tmohg1mj	173	6	provide	provide	VBP
cord-032504-tmohg1mj	173	7	hope	hope	NN
cord-032504-tmohg1mj	173	8	for	for	IN
cord-032504-tmohg1mj	173	9	expanding	expand	VBG
cord-032504-tmohg1mj	173	10	our	-PRON-	PRP$
cord-032504-tmohg1mj	173	11	understanding	understanding	NN
cord-032504-tmohg1mj	173	12	of	of	IN
cord-032504-tmohg1mj	173	13	these	these	DT
cord-032504-tmohg1mj	173	14	early	early	JJ
cord-032504-tmohg1mj	173	15	immunologic	immunologic	JJ
cord-032504-tmohg1mj	173	16	events	event	NNS
cord-032504-tmohg1mj	173	17	in	in	IN
cord-032504-tmohg1mj	173	18	humans	human	NNS
cord-032504-tmohg1mj	173	19	.	.	.
cord-032504-tmohg1mj	174	1	These	these	DT
cord-032504-tmohg1mj	174	2	tools	tool	NNS
cord-032504-tmohg1mj	174	3	have	have	VBP
cord-032504-tmohg1mj	174	4	the	the	DT
cord-032504-tmohg1mj	174	5	potential	potential	NN
cord-032504-tmohg1mj	174	6	to	to	TO
cord-032504-tmohg1mj	174	7	vastly	vastly	RB
cord-032504-tmohg1mj	174	8	enhance	enhance	VB
cord-032504-tmohg1mj	174	9	our	-PRON-	PRP$
cord-032504-tmohg1mj	174	10	current	current	JJ
cord-032504-tmohg1mj	174	11	knowledge	knowledge	NN
cord-032504-tmohg1mj	174	12	by	by	IN
cord-032504-tmohg1mj	174	13	quantifying	quantify	VBG
cord-032504-tmohg1mj	174	14	the	the	DT
cord-032504-tmohg1mj	174	15	functional	functional	JJ
cord-032504-tmohg1mj	174	16	impact	impact	NN
cord-032504-tmohg1mj	174	17	of	of	IN
cord-032504-tmohg1mj	174	18	coinfection	coinfection	NN
cord-032504-tmohg1mj	174	19	on	on	IN
cord-032504-tmohg1mj	174	20	bacterial	bacterial	JJ
cord-032504-tmohg1mj	174	21	burden	burden	NN
cord-032504-tmohg1mj	174	22	and	and	CC
cord-032504-tmohg1mj	174	23	early	early	JJ
cord-032504-tmohg1mj	174	24	human	human	JJ
cord-032504-tmohg1mj	174	25	immune	immune	JJ
cord-032504-tmohg1mj	174	26	responses	response	NNS
cord-032504-tmohg1mj	174	27	,	,	,
cord-032504-tmohg1mj	174	28	while	while	IN
cord-032504-tmohg1mj	174	29	also	also	RB
cord-032504-tmohg1mj	174	30	offering	offer	VBG
cord-032504-tmohg1mj	174	31	insight	insight	NN
cord-032504-tmohg1mj	174	32	into	into	IN
cord-032504-tmohg1mj	174	33	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	174	34	underlying	underlie	VBG
cord-032504-tmohg1mj	174	35	early	early	JJ
cord-032504-tmohg1mj	174	36	immune	immune	JJ
cord-032504-tmohg1mj	174	37	control	control	NN
cord-032504-tmohg1mj	174	38	or	or	CC
cord-032504-tmohg1mj	174	39	escape	escape	NN
cord-032504-tmohg1mj	174	40	.	.	.
cord-032504-tmohg1mj	175	1	The	the	DT
cord-032504-tmohg1mj	175	2	first	first	JJ
cord-032504-tmohg1mj	175	3	such	such	JJ
cord-032504-tmohg1mj	175	4	tool	tool	NN
cord-032504-tmohg1mj	175	5	is	be	VBZ
cord-032504-tmohg1mj	175	6	2-deoxy-2-[18F]fluoro	2-deoxy-2-[18f]fluoro	CD
cord-032504-tmohg1mj	175	7	-	-	HYPH
cord-032504-tmohg1mj	175	8	d	d	NN
cord-032504-tmohg1mj	175	9	-	-	HYPH
cord-032504-tmohg1mj	175	10	glucose	glucose	NN
cord-032504-tmohg1mj	175	11	(	(	-LRB-
cord-032504-tmohg1mj	175	12	[	[	-LRB-
cord-032504-tmohg1mj	175	13	18F]FDG	18f]fdg	CD
cord-032504-tmohg1mj	175	14	)	)	-RRB-
cord-032504-tmohg1mj	175	15	positron	positron	NN
cord-032504-tmohg1mj	175	16	emission	emission	NN
cord-032504-tmohg1mj	175	17	tomography	tomography	NN
cord-032504-tmohg1mj	175	18	combined	combine	VBN
cord-032504-tmohg1mj	175	19	with	with	IN
cord-032504-tmohg1mj	175	20	computed	compute	VBN
cord-032504-tmohg1mj	175	21	tomography	tomography	NN
cord-032504-tmohg1mj	175	22	(	(	-LRB-
cord-032504-tmohg1mj	175	23	PET	PET	NNP
cord-032504-tmohg1mj	175	24	-	-	HYPH
cord-032504-tmohg1mj	175	25	CT	CT	NNP
cord-032504-tmohg1mj	175	26	)	)	-RRB-
cord-032504-tmohg1mj	175	27	,	,	,
cord-032504-tmohg1mj	175	28	which	which	WDT
cord-032504-tmohg1mj	175	29	identifies	identify	VBZ
cord-032504-tmohg1mj	175	30	areas	area	NNS
cord-032504-tmohg1mj	175	31	of	of	IN
cord-032504-tmohg1mj	175	32	increased	increase	VBN
cord-032504-tmohg1mj	175	33	cellular	cellular	JJ
cord-032504-tmohg1mj	175	34	metabolic	metabolic	JJ
cord-032504-tmohg1mj	175	35	activity	activity	NN
cord-032504-tmohg1mj	175	36	as	as	IN
cord-032504-tmohg1mj	175	37	would	would	MD
cord-032504-tmohg1mj	175	38	occur	occur	VB
cord-032504-tmohg1mj	175	39	with	with	IN
cord-032504-tmohg1mj	175	40	an	an	DT
cord-032504-tmohg1mj	175	41	immune	immune	JJ
cord-032504-tmohg1mj	175	42	response	response	NN
cord-032504-tmohg1mj	175	43	to	to	IN
cord-032504-tmohg1mj	175	44	infection	infection	NN
cord-032504-tmohg1mj	175	45	.	.	.
cord-032504-tmohg1mj	176	1	Several	several	JJ
cord-032504-tmohg1mj	176	2	macaque	macaque	NN
cord-032504-tmohg1mj	176	3	studies	study	NNS
cord-032504-tmohg1mj	176	4	have	have	VBP
cord-032504-tmohg1mj	176	5	leveraged	leverage	VBN
cord-032504-tmohg1mj	176	6	PET	PET	NNP
cord-032504-tmohg1mj	176	7	-	-	HYPH
cord-032504-tmohg1mj	176	8	CT	ct	NN
cord-032504-tmohg1mj	176	9	imaging	imaging	NN
cord-032504-tmohg1mj	176	10	to	to	TO
cord-032504-tmohg1mj	176	11	gain	gain	VB
cord-032504-tmohg1mj	176	12	insight	insight	NN
cord-032504-tmohg1mj	176	13	into	into	IN
cord-032504-tmohg1mj	176	14	early	early	JJ
cord-032504-tmohg1mj	176	15	infection	infection	NN
cord-032504-tmohg1mj	176	16	by	by	IN
cord-032504-tmohg1mj	176	17	following	follow	VBG
cord-032504-tmohg1mj	176	18	the	the	DT
cord-032504-tmohg1mj	176	19	progression	progression	NN
cord-032504-tmohg1mj	176	20	of	of	IN
cord-032504-tmohg1mj	176	21	individual	individual	JJ
cord-032504-tmohg1mj	176	22	granulomas	granuloma	NNS
cord-032504-tmohg1mj	176	23	after	after	IN
cord-032504-tmohg1mj	176	24	aerosol	aerosol	NN
cord-032504-tmohg1mj	176	25	infection	infection	NN
cord-032504-tmohg1mj	176	26	[	[	-LRB-
cord-032504-tmohg1mj	176	27	53	53	CD
cord-032504-tmohg1mj	176	28	,	,	,
cord-032504-tmohg1mj	176	29	54	54	CD
cord-032504-tmohg1mj	176	30	,	,	,
cord-032504-tmohg1mj	176	31	131	131	CD
cord-032504-tmohg1mj	176	32	,	,	,
cord-032504-tmohg1mj	176	33	132	132	CD
cord-032504-tmohg1mj	176	34	]	]	-RRB-
cord-032504-tmohg1mj	176	35	.	.	.
cord-032504-tmohg1mj	177	1	PET	PET	NNP
cord-032504-tmohg1mj	177	2	-	-	HYPH
cord-032504-tmohg1mj	177	3	CT	CT	NNP
cord-032504-tmohg1mj	177	4	has	have	VBZ
cord-032504-tmohg1mj	177	5	also	also	RB
cord-032504-tmohg1mj	177	6	been	be	VBN
cord-032504-tmohg1mj	177	7	employed	employ	VBN
cord-032504-tmohg1mj	177	8	to	to	TO
cord-032504-tmohg1mj	177	9	study	study	VB
cord-032504-tmohg1mj	177	10	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	177	11	in	in	IN
cord-032504-tmohg1mj	177	12	humans	human	NNS
cord-032504-tmohg1mj	177	13	,	,	,
cord-032504-tmohg1mj	177	14	including	include	VBG
cord-032504-tmohg1mj	177	15	a	a	DT
cord-032504-tmohg1mj	177	16	cohort	cohort	NN
cord-032504-tmohg1mj	177	17	of	of	IN
cord-032504-tmohg1mj	177	18	35	35	CD
cord-032504-tmohg1mj	177	19	people	people	NNS
cord-032504-tmohg1mj	177	20	with	with	IN
cord-032504-tmohg1mj	177	21	HIV	HIV	NNP
cord-032504-tmohg1mj	177	22	and	and	CC
cord-032504-tmohg1mj	177	23	latent	latent	JJ
cord-032504-tmohg1mj	177	24	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	177	25	infection	infection	NN
cord-032504-tmohg1mj	177	26	,	,	,
cord-032504-tmohg1mj	177	27	10	10	CD
cord-032504-tmohg1mj	177	28	of	of	IN
cord-032504-tmohg1mj	177	29	whom	whom	WP
cord-032504-tmohg1mj	177	30	had	have	VBD
cord-032504-tmohg1mj	177	31	PET	pet	NN
cord-032504-tmohg1mj	177	32	-	-	HYPH
cord-032504-tmohg1mj	177	33	avid	avid	JJ
cord-032504-tmohg1mj	177	34	lesions	lesion	NNS
cord-032504-tmohg1mj	177	35	suspicious	suspicious	JJ
cord-032504-tmohg1mj	177	36	for	for	IN
cord-032504-tmohg1mj	177	37	subclinical	subclinical	JJ
cord-032504-tmohg1mj	177	38	disease	disease	NN
cord-032504-tmohg1mj	177	39	[	[	-LRB-
cord-032504-tmohg1mj	177	40	133	133	CD
cord-032504-tmohg1mj	177	41	]	]	-RRB-
cord-032504-tmohg1mj	177	42	.	.	.
cord-032504-tmohg1mj	178	1	Those	those	DT
cord-032504-tmohg1mj	178	2	with	with	IN
cord-032504-tmohg1mj	178	3	PET	pet	JJ
cord-032504-tmohg1mj	178	4	activity	activity	NN
cord-032504-tmohg1mj	178	5	were	be	VBD
cord-032504-tmohg1mj	178	6	significantly	significantly	RB
cord-032504-tmohg1mj	178	7	more	more	RBR
cord-032504-tmohg1mj	178	8	likely	likely	JJ
cord-032504-tmohg1mj	178	9	to	to	TO
cord-032504-tmohg1mj	178	10	develop	develop	VB
cord-032504-tmohg1mj	178	11	active	active	JJ
cord-032504-tmohg1mj	178	12	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	178	13	disease	disease	NN
cord-032504-tmohg1mj	178	14	during	during	IN
cord-032504-tmohg1mj	178	15	the	the	DT
cord-032504-tmohg1mj	178	16	following	follow	VBG
cord-032504-tmohg1mj	178	17	6	6	CD
cord-032504-tmohg1mj	178	18	months	month	NNS
cord-032504-tmohg1mj	178	19	,	,	,
cord-032504-tmohg1mj	178	20	suggesting	suggest	VBG
cord-032504-tmohg1mj	178	21	metabolic	metabolic	JJ
cord-032504-tmohg1mj	178	22	activity	activity	NN
cord-032504-tmohg1mj	178	23	on	on	IN
cord-032504-tmohg1mj	178	24	PET	pet	NN
cord-032504-tmohg1mj	178	25	imaging	imaging	NN
cord-032504-tmohg1mj	178	26	may	may	MD
cord-032504-tmohg1mj	178	27	be	be	VB
cord-032504-tmohg1mj	178	28	able	able	JJ
cord-032504-tmohg1mj	178	29	to	to	TO
cord-032504-tmohg1mj	178	30	identify	identify	VB
cord-032504-tmohg1mj	178	31	patients	patient	NNS
cord-032504-tmohg1mj	178	32	with	with	IN
cord-032504-tmohg1mj	178	33	ineffective	ineffective	JJ
cord-032504-tmohg1mj	178	34	early	early	JJ
cord-032504-tmohg1mj	178	35	immune	immune	JJ
cord-032504-tmohg1mj	178	36	responses	response	NNS
cord-032504-tmohg1mj	178	37	to	to	IN
cord-032504-tmohg1mj	178	38	Mtb	Mtb	NNP
cord-032504-tmohg1mj	178	39	infection	infection	NN
cord-032504-tmohg1mj	178	40	.	.	.
cord-032504-tmohg1mj	179	1	Blood	blood	NN
cord-032504-tmohg1mj	179	2	-	-	HYPH
cord-032504-tmohg1mj	179	3	based	base	VBN
cord-032504-tmohg1mj	179	4	immunologic	immunologic	JJ
cord-032504-tmohg1mj	179	5	signatures	signature	NNS
cord-032504-tmohg1mj	179	6	represent	represent	VBP
cord-032504-tmohg1mj	179	7	another	another	DT
cord-032504-tmohg1mj	179	8	potential	potential	JJ
cord-032504-tmohg1mj	179	9	avenue	avenue	NN
cord-032504-tmohg1mj	179	10	for	for	IN
cord-032504-tmohg1mj	179	11	studying	study	VBG
cord-032504-tmohg1mj	179	12	early	early	JJ
cord-032504-tmohg1mj	179	13	infection	infection	NN
cord-032504-tmohg1mj	179	14	.	.	.
cord-032504-tmohg1mj	180	1	Recent	recent	JJ
cord-032504-tmohg1mj	180	2	studies	study	NNS
cord-032504-tmohg1mj	180	3	in	in	IN
cord-032504-tmohg1mj	180	4	macaques	macaque	NNS
cord-032504-tmohg1mj	180	5	and	and	CC
cord-032504-tmohg1mj	180	6	humans	human	NNS
cord-032504-tmohg1mj	180	7	have	have	VBP
cord-032504-tmohg1mj	180	8	identified	identify	VBN
cord-032504-tmohg1mj	180	9	RNA	RNA	NNP
cord-032504-tmohg1mj	180	10	signatures	signature	NNS
cord-032504-tmohg1mj	180	11	predictive	predictive	JJ
cord-032504-tmohg1mj	180	12	of	of	IN
cord-032504-tmohg1mj	180	13	progression	progression	NN
cord-032504-tmohg1mj	180	14	to	to	IN
cord-032504-tmohg1mj	180	15	active	active	JJ
cord-032504-tmohg1mj	180	16	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	180	17	disease	disease	NN
cord-032504-tmohg1mj	180	18	[	[	-LRB-
cord-032504-tmohg1mj	180	19	134	134	CD
cord-032504-tmohg1mj	180	20	]	]	-RRB-
cord-032504-tmohg1mj	180	21	[	[	-LRB-
cord-032504-tmohg1mj	180	22	135	135	CD
cord-032504-tmohg1mj	180	23	]	]	-RRB-
cord-032504-tmohg1mj	180	24	[	[	-LRB-
cord-032504-tmohg1mj	180	25	136	136	CD
cord-032504-tmohg1mj	180	26	]	]	-RRB-
cord-032504-tmohg1mj	180	27	.	.	.
cord-032504-tmohg1mj	181	1	Notably	notably	RB
cord-032504-tmohg1mj	181	2	,	,	,
cord-032504-tmohg1mj	181	3	the	the	DT
cord-032504-tmohg1mj	181	4	macaque	macaque	NN
cord-032504-tmohg1mj	181	5	signature	signature	NN
cord-032504-tmohg1mj	181	6	was	be	VBD
cord-032504-tmohg1mj	181	7	predictive	predictive	JJ
cord-032504-tmohg1mj	181	8	just	just	RB
cord-032504-tmohg1mj	181	9	3	3	CD
cord-032504-tmohg1mj	181	10	-	-	SYM
cord-032504-tmohg1mj	181	11	6	6	CD
cord-032504-tmohg1mj	181	12	weeks	week	NNS
cord-032504-tmohg1mj	181	13	after	after	IN
cord-032504-tmohg1mj	181	14	aerosol	aerosol	NN
cord-032504-tmohg1mj	181	15	infection	infection	NN
cord-032504-tmohg1mj	181	16	,	,	,
cord-032504-tmohg1mj	181	17	providing	provide	VBG
cord-032504-tmohg1mj	181	18	compelling	compelling	JJ
cord-032504-tmohg1mj	181	19	evidence	evidence	NN
cord-032504-tmohg1mj	181	20	for	for	IN
cord-032504-tmohg1mj	181	21	the	the	DT
cord-032504-tmohg1mj	181	22	value	value	NN
cord-032504-tmohg1mj	181	23	of	of	IN
cord-032504-tmohg1mj	181	24	these	these	DT
cord-032504-tmohg1mj	181	25	signatures	signature	NNS
cord-032504-tmohg1mj	181	26	even	even	RB
cord-032504-tmohg1mj	181	27	very	very	RB
cord-032504-tmohg1mj	181	28	early	early	RB
cord-032504-tmohg1mj	181	29	in	in	IN
cord-032504-tmohg1mj	181	30	infection	infection	NN
cord-032504-tmohg1mj	181	31	.	.	.
cord-032504-tmohg1mj	182	1	This	this	DT
cord-032504-tmohg1mj	182	2	signature	signature	NN
cord-032504-tmohg1mj	182	3	also	also	RB
cord-032504-tmohg1mj	182	4	identified	identify	VBD
cord-032504-tmohg1mj	182	5	a	a	DT
cord-032504-tmohg1mj	182	6	novel	novel	JJ
cord-032504-tmohg1mj	182	7	gene	gene	NN
cord-032504-tmohg1mj	182	8	in	in	IN
cord-032504-tmohg1mj	182	9	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	182	10	pathogenesis	pathogenesis	NN
cord-032504-tmohg1mj	182	11	,	,	,
cord-032504-tmohg1mj	182	12	PRDX2	PRDX2	NNP
cord-032504-tmohg1mj	182	13	,	,	,
cord-032504-tmohg1mj	182	14	a	a	DT
cord-032504-tmohg1mj	182	15	member	member	NN
cord-032504-tmohg1mj	182	16	of	of	IN
cord-032504-tmohg1mj	182	17	the	the	DT
cord-032504-tmohg1mj	182	18	reactive	reactive	JJ
cord-032504-tmohg1mj	182	19	oxygen	oxygen	NN
cord-032504-tmohg1mj	182	20	species	specie	NNS
cord-032504-tmohg1mj	182	21	scavenger	scavenger	NN
cord-032504-tmohg1mj	182	22	system	system	NN
cord-032504-tmohg1mj	182	23	.	.	.
cord-032504-tmohg1mj	183	1	Further	further	JJ
cord-032504-tmohg1mj	183	2	studies	study	NNS
cord-032504-tmohg1mj	183	3	are	be	VBP
cord-032504-tmohg1mj	183	4	warranted	warrant	VBN
cord-032504-tmohg1mj	183	5	to	to	TO
cord-032504-tmohg1mj	183	6	explore	explore	VB
cord-032504-tmohg1mj	183	7	the	the	DT
cord-032504-tmohg1mj	183	8	role	role	NN
cord-032504-tmohg1mj	183	9	of	of	IN
cord-032504-tmohg1mj	183	10	PRDX2	prdx2	DT
cord-032504-tmohg1mj	183	11	in	in	IN
cord-032504-tmohg1mj	183	12	early	early	JJ
cord-032504-tmohg1mj	183	13	infection	infection	NN
cord-032504-tmohg1mj	183	14	,	,	,
cord-032504-tmohg1mj	183	15	and	and	CC
cord-032504-tmohg1mj	183	16	how	how	WRB
cord-032504-tmohg1mj	183	17	that	that	DT
cord-032504-tmohg1mj	183	18	response	response	NN
cord-032504-tmohg1mj	183	19	may	may	MD
cord-032504-tmohg1mj	183	20	be	be	VB
cord-032504-tmohg1mj	183	21	skewed	skew	VBN
cord-032504-tmohg1mj	183	22	by	by	IN
cord-032504-tmohg1mj	183	23	HIV	HIV	NNP
cord-032504-tmohg1mj	183	24	and	and	CC
cord-032504-tmohg1mj	183	25	other	other	JJ
cord-032504-tmohg1mj	183	26	known	know	VBN
cord-032504-tmohg1mj	183	27	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	183	28	risk	risk	NN
cord-032504-tmohg1mj	183	29	factors	factor	NNS
cord-032504-tmohg1mj	183	30	.	.	.
cord-032504-tmohg1mj	184	1	Similarly	similarly	RB
cord-032504-tmohg1mj	184	2	,	,	,
cord-032504-tmohg1mj	184	3	characterization	characterization	NN
cord-032504-tmohg1mj	184	4	of	of	IN
cord-032504-tmohg1mj	184	5	Mtb	Mtb	NNP
cord-032504-tmohg1mj	184	6	-	-	HYPH
cord-032504-tmohg1mj	184	7	specific	specific	JJ
cord-032504-tmohg1mj	184	8	T	T	NNP
cord-032504-tmohg1mj	184	9	cell	cell	NN
cord-032504-tmohg1mj	184	10	responses	response	NNS
cord-032504-tmohg1mj	184	11	may	may	MD
cord-032504-tmohg1mj	184	12	provide	provide	VB
cord-032504-tmohg1mj	184	13	another	another	DT
cord-032504-tmohg1mj	184	14	means	means	NN
cord-032504-tmohg1mj	184	15	for	for	IN
cord-032504-tmohg1mj	184	16	understanding	understand	VBG
cord-032504-tmohg1mj	184	17	adaptive	adaptive	JJ
cord-032504-tmohg1mj	184	18	immune	immune	JJ
cord-032504-tmohg1mj	184	19	responses	response	NNS
cord-032504-tmohg1mj	184	20	important	important	JJ
cord-032504-tmohg1mj	184	21	in	in	IN
cord-032504-tmohg1mj	184	22	early	early	JJ
cord-032504-tmohg1mj	184	23	infection	infection	NN
cord-032504-tmohg1mj	184	24	.	.	.
cord-032504-tmohg1mj	185	1	In	in	IN
cord-032504-tmohg1mj	185	2	a	a	DT
cord-032504-tmohg1mj	185	3	recent	recent	JJ
cord-032504-tmohg1mj	185	4	report	report	NN
cord-032504-tmohg1mj	185	5	of	of	IN
cord-032504-tmohg1mj	185	6	a	a	DT
cord-032504-tmohg1mj	185	7	whole	whole	JJ
cord-032504-tmohg1mj	185	8	blood	blood	NN
cord-032504-tmohg1mj	185	9	assay	assay	NN
cord-032504-tmohg1mj	185	10	of	of	IN
cord-032504-tmohg1mj	185	11	T	T	NNP
cord-032504-tmohg1mj	185	12	cell	cell	NN
cord-032504-tmohg1mj	185	13	responses	response	NNS
cord-032504-tmohg1mj	185	14	to	to	IN
cord-032504-tmohg1mj	185	15	60	60	CD
cord-032504-tmohg1mj	185	16	Mtb	Mtb	NNP
cord-032504-tmohg1mj	185	17	antigens	antigen	NNS
cord-032504-tmohg1mj	185	18	,	,	,
cord-032504-tmohg1mj	185	19	immunogenic	immunogenic	JJ
cord-032504-tmohg1mj	185	20	Mtb	Mtb	NNP
cord-032504-tmohg1mj	185	21	antigens	antigen	NNS
cord-032504-tmohg1mj	185	22	were	be	VBD
cord-032504-tmohg1mj	185	23	successfully	successfully	RB
cord-032504-tmohg1mj	185	24	identified	identify	VBN
cord-032504-tmohg1mj	185	25	across	across	IN
cord-032504-tmohg1mj	185	26	a	a	DT
cord-032504-tmohg1mj	185	27	diverse	diverse	JJ
cord-032504-tmohg1mj	185	28	range	range	NN
cord-032504-tmohg1mj	185	29	of	of	IN
cord-032504-tmohg1mj	185	30	populations	population	NNS
cord-032504-tmohg1mj	185	31	and	and	CC
cord-032504-tmohg1mj	185	32	infectious	infectious	JJ
cord-032504-tmohg1mj	185	33	states	state	NNS
cord-032504-tmohg1mj	185	34	[	[	-LRB-
cord-032504-tmohg1mj	185	35	137	137	CD
cord-032504-tmohg1mj	185	36	]	]	-RRB-
cord-032504-tmohg1mj	185	37	.	.	.
cord-032504-tmohg1mj	186	1	Longitudinal	longitudinal	JJ
cord-032504-tmohg1mj	186	2	studies	study	NNS
cord-032504-tmohg1mj	186	3	are	be	VBP
cord-032504-tmohg1mj	186	4	underway	underway	JJ
cord-032504-tmohg1mj	186	5	to	to	TO
cord-032504-tmohg1mj	186	6	determine	determine	VB
cord-032504-tmohg1mj	186	7	if	if	IN
cord-032504-tmohg1mj	186	8	these	these	DT
cord-032504-tmohg1mj	186	9	T	T	NNP
cord-032504-tmohg1mj	186	10	cell	cell	NN
cord-032504-tmohg1mj	186	11	signatures	signature	NNS
cord-032504-tmohg1mj	186	12	correlate	correlate	VBP
cord-032504-tmohg1mj	186	13	with	with	IN
cord-032504-tmohg1mj	186	14	early	early	JJ
cord-032504-tmohg1mj	186	15	immune	immune	JJ
cord-032504-tmohg1mj	186	16	responses	response	NNS
cord-032504-tmohg1mj	186	17	-	-	:
cord-032504-tmohg1mj	186	18	both	both	CC
cord-032504-tmohg1mj	186	19	those	those	DT
cord-032504-tmohg1mj	186	20	that	that	WDT
cord-032504-tmohg1mj	186	21	clear	clear	JJ
cord-032504-tmohg1mj	186	22	infection	infection	NN
cord-032504-tmohg1mj	186	23	and	and	CC
cord-032504-tmohg1mj	186	24	those	those	DT
cord-032504-tmohg1mj	186	25	that	that	WDT
cord-032504-tmohg1mj	186	26	permit	permit	VBP
cord-032504-tmohg1mj	186	27	ongoing	ongoing	JJ
cord-032504-tmohg1mj	186	28	Mtb	Mtb	NNP
cord-032504-tmohg1mj	186	29	growth	growth	NN
cord-032504-tmohg1mj	186	30	and	and	CC
cord-032504-tmohg1mj	186	31	dissemination	dissemination	NN
cord-032504-tmohg1mj	186	32	.	.	.
cord-032504-tmohg1mj	187	1	Yet	yet	RB
cord-032504-tmohg1mj	187	2	another	another	DT
cord-032504-tmohg1mj	187	3	tool	tool	NN
cord-032504-tmohg1mj	187	4	for	for	IN
cord-032504-tmohg1mj	187	5	identifying	identify	VBG
cord-032504-tmohg1mj	187	6	and	and	CC
cord-032504-tmohg1mj	187	7	studying	study	VBG
cord-032504-tmohg1mj	187	8	early	early	JJ
cord-032504-tmohg1mj	187	9	infection	infection	NN
cord-032504-tmohg1mj	187	10	is	be	VBZ
cord-032504-tmohg1mj	187	11	plasma	plasma	NN
cord-032504-tmohg1mj	187	12	metabolomics	metabolomic	NNS
cord-032504-tmohg1mj	187	13	,	,	,
cord-032504-tmohg1mj	187	14	in	in	IN
cord-032504-tmohg1mj	187	15	which	which	WDT
cord-032504-tmohg1mj	187	16	small	small	JJ
cord-032504-tmohg1mj	187	17	molecules	molecule	NNS
cord-032504-tmohg1mj	187	18	are	be	VBP
cord-032504-tmohg1mj	187	19	identified	identify	VBN
cord-032504-tmohg1mj	187	20	using	use	VBG
cord-032504-tmohg1mj	187	21	high	high	JJ
cord-032504-tmohg1mj	187	22	-	-	HYPH
cord-032504-tmohg1mj	187	23	resolution	resolution	NN
cord-032504-tmohg1mj	187	24	mass	mass	NN
cord-032504-tmohg1mj	187	25	spectrometry	spectrometry	NN
cord-032504-tmohg1mj	187	26	.	.	.
cord-032504-tmohg1mj	188	1	This	this	DT
cord-032504-tmohg1mj	188	2	approach	approach	NN
cord-032504-tmohg1mj	188	3	has	have	VBZ
cord-032504-tmohg1mj	188	4	been	be	VBN
cord-032504-tmohg1mj	188	5	successfully	successfully	RB
cord-032504-tmohg1mj	188	6	employed	employ	VBN
cord-032504-tmohg1mj	188	7	to	to	TO
cord-032504-tmohg1mj	188	8	identify	identify	VB
cord-032504-tmohg1mj	188	9	direct	direct	JJ
cord-032504-tmohg1mj	188	10	metabolites	metabolite	NNS
cord-032504-tmohg1mj	188	11	of	of	IN
cord-032504-tmohg1mj	188	12	Mtb	Mtb	NNP
cord-032504-tmohg1mj	188	13	,	,	,
cord-032504-tmohg1mj	188	14	and	and	CC
cord-032504-tmohg1mj	188	15	may	may	MD
cord-032504-tmohg1mj	188	16	be	be	VB
cord-032504-tmohg1mj	188	17	able	able	JJ
cord-032504-tmohg1mj	188	18	to	to	TO
cord-032504-tmohg1mj	188	19	identify	identify	VB
cord-032504-tmohg1mj	188	20	low	low	JJ
cord-032504-tmohg1mj	188	21	levels	level	NNS
cord-032504-tmohg1mj	188	22	even	even	RB
cord-032504-tmohg1mj	188	23	early	early	RB
cord-032504-tmohg1mj	188	24	in	in	IN
cord-032504-tmohg1mj	188	25	infection	infection	NN
cord-032504-tmohg1mj	188	26	.	.	.
cord-032504-tmohg1mj	189	1	Metabolomics	Metabolomics	NNP
cord-032504-tmohg1mj	189	2	has	have	VBZ
cord-032504-tmohg1mj	189	3	also	also	RB
cord-032504-tmohg1mj	189	4	been	be	VBN
cord-032504-tmohg1mj	189	5	used	use	VBN
cord-032504-tmohg1mj	189	6	to	to	TO
cord-032504-tmohg1mj	189	7	identify	identify	VB
cord-032504-tmohg1mj	189	8	distinct	distinct	JJ
cord-032504-tmohg1mj	189	9	signatures	signature	NNS
cord-032504-tmohg1mj	189	10	of	of	IN
cord-032504-tmohg1mj	189	11	the	the	DT
cord-032504-tmohg1mj	189	12	host	host	NN
cord-032504-tmohg1mj	189	13	immune	immune	JJ
cord-032504-tmohg1mj	189	14	response	response	NN
cord-032504-tmohg1mj	189	15	,	,	,
cord-032504-tmohg1mj	189	16	whereby	whereby	WRB
cord-032504-tmohg1mj	189	17	investigators	investigator	NNS
cord-032504-tmohg1mj	189	18	were	be	VBD
cord-032504-tmohg1mj	189	19	able	able	JJ
cord-032504-tmohg1mj	189	20	to	to	TO
cord-032504-tmohg1mj	189	21	distinguish	distinguish	VB
cord-032504-tmohg1mj	189	22	between	between	IN
cord-032504-tmohg1mj	189	23	risk	risk	NN
cord-032504-tmohg1mj	189	24	-	-	HYPH
cord-032504-tmohg1mj	189	25	associated	associate	VBN
cord-032504-tmohg1mj	189	26	metabolites	metabolite	NNS
cord-032504-tmohg1mj	189	27	associated	associate	VBN
cord-032504-tmohg1mj	189	28	with	with	IN
cord-032504-tmohg1mj	189	29	a	a	DT
cord-032504-tmohg1mj	189	30	higher	high	JJR
cord-032504-tmohg1mj	189	31	likelihood	likelihood	NN
cord-032504-tmohg1mj	189	32	of	of	IN
cord-032504-tmohg1mj	189	33	progression	progression	NN
cord-032504-tmohg1mj	189	34	to	to	IN
cord-032504-tmohg1mj	189	35	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	189	36	disease	disease	NN
cord-032504-tmohg1mj	189	37	and	and	CC
cord-032504-tmohg1mj	189	38	disease	disease	NN
cord-032504-tmohg1mj	189	39	-	-	HYPH
cord-032504-tmohg1mj	189	40	associated	associate	VBN
cord-032504-tmohg1mj	189	41	metabolites	metabolite	NNS
cord-032504-tmohg1mj	189	42	that	that	WDT
cord-032504-tmohg1mj	189	43	increased	increase	VBD
cord-032504-tmohg1mj	189	44	in	in	IN
cord-032504-tmohg1mj	189	45	a	a	DT
cord-032504-tmohg1mj	189	46	time	time	NN
cord-032504-tmohg1mj	189	47	-	-	HYPH
cord-032504-tmohg1mj	189	48	dependent	dependent	JJ
cord-032504-tmohg1mj	189	49	manner	manner	NN
cord-032504-tmohg1mj	189	50	among	among	IN
cord-032504-tmohg1mj	189	51	those	those	DT
cord-032504-tmohg1mj	189	52	with	with	IN
cord-032504-tmohg1mj	189	53	progression	progression	NN
cord-032504-tmohg1mj	189	54	to	to	IN
cord-032504-tmohg1mj	189	55	active	active	JJ
cord-032504-tmohg1mj	189	56	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	189	57	disease	disease	NN
cord-032504-tmohg1mj	189	58	[	[	-LRB-
cord-032504-tmohg1mj	189	59	138	138	CD
cord-032504-tmohg1mj	189	60	]	]	-RRB-
cord-032504-tmohg1mj	189	61	[	[	-LRB-
cord-032504-tmohg1mj	189	62	139	139	CD
cord-032504-tmohg1mj	189	63	]	]	-RRB-
cord-032504-tmohg1mj	189	64	[	[	-LRB-
cord-032504-tmohg1mj	189	65	140	140	CD
cord-032504-tmohg1mj	189	66	]	]	-RRB-
cord-032504-tmohg1mj	189	67	.	.	.
cord-032504-tmohg1mj	190	1	Looking	look	VBG
cord-032504-tmohg1mj	190	2	ahead	ahead	RB
cord-032504-tmohg1mj	190	3	,	,	,
cord-032504-tmohg1mj	190	4	it	-PRON-	PRP
cord-032504-tmohg1mj	190	5	will	will	MD
cord-032504-tmohg1mj	190	6	be	be	VB
cord-032504-tmohg1mj	190	7	important	important	JJ
cord-032504-tmohg1mj	190	8	to	to	TO
cord-032504-tmohg1mj	190	9	determine	determine	VB
cord-032504-tmohg1mj	190	10	whether	whether	IN
cord-032504-tmohg1mj	190	11	these	these	DT
cord-032504-tmohg1mj	190	12	metabolic	metabolic	JJ
cord-032504-tmohg1mj	190	13	signatures	signature	NNS
cord-032504-tmohg1mj	190	14	are	be	VBP
cord-032504-tmohg1mj	190	15	similarly	similarly	RB
cord-032504-tmohg1mj	190	16	predictive	predictive	JJ
cord-032504-tmohg1mj	190	17	and	and	CC
cord-032504-tmohg1mj	190	18	valid	valid	JJ
cord-032504-tmohg1mj	190	19	in	in	IN
cord-032504-tmohg1mj	190	20	people	people	NNS
cord-032504-tmohg1mj	190	21	with	with	IN
cord-032504-tmohg1mj	190	22	HIV	HIV	NNP
cord-032504-tmohg1mj	190	23	.	.	.
cord-032504-tmohg1mj	191	1	Across	across	IN
cord-032504-tmohg1mj	191	2	the	the	DT
cord-032504-tmohg1mj	191	3	scientific	scientific	JJ
cord-032504-tmohg1mj	191	4	community	community	NN
cord-032504-tmohg1mj	191	5	,	,	,
cord-032504-tmohg1mj	191	6	there	there	EX
cord-032504-tmohg1mj	191	7	is	be	VBZ
cord-032504-tmohg1mj	191	8	overwhelming	overwhelming	JJ
cord-032504-tmohg1mj	191	9	consensus	consensus	NN
cord-032504-tmohg1mj	191	10	over	over	IN
cord-032504-tmohg1mj	191	11	the	the	DT
cord-032504-tmohg1mj	191	12	need	need	NN
cord-032504-tmohg1mj	191	13	to	to	TO
cord-032504-tmohg1mj	191	14	understand	understand	VB
cord-032504-tmohg1mj	191	15	protective	protective	JJ
cord-032504-tmohg1mj	191	16	immunity	immunity	NN
cord-032504-tmohg1mj	191	17	to	to	IN
cord-032504-tmohg1mj	191	18	Mtb	Mtb	NNP
cord-032504-tmohg1mj	191	19	[	[	-LRB-
cord-032504-tmohg1mj	191	20	55	55	CD
cord-032504-tmohg1mj	191	21	]	]	-RRB-
cord-032504-tmohg1mj	191	22	.	.	.
cord-032504-tmohg1mj	192	1	As	as	IN
cord-032504-tmohg1mj	192	2	a	a	DT
cord-032504-tmohg1mj	192	3	framework	framework	NN
cord-032504-tmohg1mj	192	4	for	for	IN
cord-032504-tmohg1mj	192	5	considering	consider	VBG
cord-032504-tmohg1mj	192	6	early	early	JJ
cord-032504-tmohg1mj	192	7	immunologic	immunologic	JJ
cord-032504-tmohg1mj	192	8	responses	response	NNS
cord-032504-tmohg1mj	192	9	to	to	IN
cord-032504-tmohg1mj	192	10	Mtb	Mtb	NNP
cord-032504-tmohg1mj	192	11	,	,	,
cord-032504-tmohg1mj	192	12	the	the	DT
cord-032504-tmohg1mj	192	13	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	192	14	set	set	NNP
cord-032504-tmohg1mj	192	15	point	point	NN
cord-032504-tmohg1mj	192	16	provides	provide	VBZ
cord-032504-tmohg1mj	192	17	a	a	DT
cord-032504-tmohg1mj	192	18	useful	useful	JJ
cord-032504-tmohg1mj	192	19	construct	construct	NN
cord-032504-tmohg1mj	192	20	for	for	IN
cord-032504-tmohg1mj	192	21	understanding	understand	VBG
cord-032504-tmohg1mj	192	22	the	the	DT
cord-032504-tmohg1mj	192	23	impact	impact	NN
cord-032504-tmohg1mj	192	24	of	of	IN
cord-032504-tmohg1mj	192	25	early	early	JJ
cord-032504-tmohg1mj	192	26	immune	immune	JJ
cord-032504-tmohg1mj	192	27	control	control	NN
cord-032504-tmohg1mj	192	28	and	and	CC
cord-032504-tmohg1mj	192	29	clinical	clinical	JJ
cord-032504-tmohg1mj	192	30	outcomes	outcome	NNS
cord-032504-tmohg1mj	192	31	of	of	IN
cord-032504-tmohg1mj	192	32	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	192	33	.	.	.
cord-032504-tmohg1mj	193	1	Given	give	VBN
cord-032504-tmohg1mj	193	2	the	the	DT
cord-032504-tmohg1mj	193	3	disproportionate	disproportionate	JJ
cord-032504-tmohg1mj	193	4	burden	burden	NN
cord-032504-tmohg1mj	193	5	of	of	IN
cord-032504-tmohg1mj	193	6	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	193	7	disease	disease	NN
cord-032504-tmohg1mj	193	8	and	and	CC
cord-032504-tmohg1mj	193	9	deaths	death	NNS
cord-032504-tmohg1mj	193	10	among	among	IN
cord-032504-tmohg1mj	193	11	people	people	NNS
cord-032504-tmohg1mj	193	12	with	with	IN
cord-032504-tmohg1mj	193	13	HIV	HIV	NNP
cord-032504-tmohg1mj	193	14	despite	despite	IN
cord-032504-tmohg1mj	193	15	widespread	widespread	JJ
cord-032504-tmohg1mj	193	16	ART	art	NN
cord-032504-tmohg1mj	193	17	[	[	-LRB-
cord-032504-tmohg1mj	193	18	23	23	CD
cord-032504-tmohg1mj	193	19	]	]	-RRB-
cord-032504-tmohg1mj	193	20	,	,	,
cord-032504-tmohg1mj	193	21	it	-PRON-	PRP
cord-032504-tmohg1mj	193	22	is	be	VBZ
cord-032504-tmohg1mj	193	23	imperative	imperative	JJ
cord-032504-tmohg1mj	193	24	to	to	TO
cord-032504-tmohg1mj	193	25	study	study	VB
cord-032504-tmohg1mj	193	26	the	the	DT
cord-032504-tmohg1mj	193	27	unique	unique	JJ
cord-032504-tmohg1mj	193	28	impacts	impact	NNS
cord-032504-tmohg1mj	193	29	of	of	IN
cord-032504-tmohg1mj	193	30	HIV	HIV	NNP
cord-032504-tmohg1mj	193	31	on	on	IN
cord-032504-tmohg1mj	193	32	Mtb	Mtb	NNP
cord-032504-tmohg1mj	193	33	infection	infection	NN
cord-032504-tmohg1mj	193	34	and	and	CC
cord-032504-tmohg1mj	193	35	susceptibility	susceptibility	NN
cord-032504-tmohg1mj	193	36	.	.	.
cord-032504-tmohg1mj	194	1	To	to	IN
cord-032504-tmohg1mj	194	2	date	date	NN
cord-032504-tmohg1mj	194	3	,	,	,
cord-032504-tmohg1mj	194	4	research	research	NN
cord-032504-tmohg1mj	194	5	evaluating	evaluate	VBG
cord-032504-tmohg1mj	194	6	the	the	DT
cord-032504-tmohg1mj	194	7	effects	effect	NNS
cord-032504-tmohg1mj	194	8	of	of	IN
cord-032504-tmohg1mj	194	9	HIV	HIV	NNP
cord-032504-tmohg1mj	194	10	on	on	IN
cord-032504-tmohg1mj	194	11	the	the	DT
cord-032504-tmohg1mj	194	12	alveolar	alveolar	JJ
cord-032504-tmohg1mj	194	13	macrophage	macrophage	NN
cord-032504-tmohg1mj	194	14	response	response	NN
cord-032504-tmohg1mj	194	15	to	to	IN
cord-032504-tmohg1mj	194	16	Mtb	Mtb	NNP
cord-032504-tmohg1mj	194	17	has	have	VBZ
cord-032504-tmohg1mj	194	18	been	be	VBN
cord-032504-tmohg1mj	194	19	relatively	relatively	RB
cord-032504-tmohg1mj	194	20	limited	limit	VBN
cord-032504-tmohg1mj	194	21	,	,	,
cord-032504-tmohg1mj	194	22	particularly	particularly	RB
cord-032504-tmohg1mj	194	23	with	with	IN
cord-032504-tmohg1mj	194	24	regard	regard	NN
cord-032504-tmohg1mj	194	25	to	to	IN
cord-032504-tmohg1mj	194	26	the	the	DT
cord-032504-tmohg1mj	194	27	critical	critical	JJ
cord-032504-tmohg1mj	194	28	early	early	JJ
cord-032504-tmohg1mj	194	29	events	event	NNS
cord-032504-tmohg1mj	194	30	that	that	WDT
cord-032504-tmohg1mj	194	31	help	help	VBP
cord-032504-tmohg1mj	194	32	to	to	TO
cord-032504-tmohg1mj	194	33	dictate	dictate	VB
cord-032504-tmohg1mj	194	34	the	the	DT
cord-032504-tmohg1mj	194	35	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	194	36	set	set	NNP
cord-032504-tmohg1mj	194	37	point	point	NN
cord-032504-tmohg1mj	194	38	.	.	.
cord-032504-tmohg1mj	195	1	While	while	IN
cord-032504-tmohg1mj	195	2	we	-PRON-	PRP
cord-032504-tmohg1mj	195	3	believe	believe	VBP
cord-032504-tmohg1mj	195	4	that	that	IN
cord-032504-tmohg1mj	195	5	a	a	DT
cord-032504-tmohg1mj	195	6	higher	high	JJR
cord-032504-tmohg1mj	195	7	mycobacterial	mycobacterial	NN
cord-032504-tmohg1mj	195	8	set	set	NN
cord-032504-tmohg1mj	195	9	point	point	NN
cord-032504-tmohg1mj	195	10	is	be	VBZ
cord-032504-tmohg1mj	195	11	a	a	DT
cord-032504-tmohg1mj	195	12	key	key	JJ
cord-032504-tmohg1mj	195	13	contributor	contributor	NN
cord-032504-tmohg1mj	195	14	to	to	IN
cord-032504-tmohg1mj	195	15	the	the	DT
cord-032504-tmohg1mj	195	16	increased	increase	VBN
cord-032504-tmohg1mj	195	17	morbidity	morbidity	NN
cord-032504-tmohg1mj	195	18	among	among	IN
cord-032504-tmohg1mj	195	19	people	people	NNS
cord-032504-tmohg1mj	195	20	with	with	IN
cord-032504-tmohg1mj	195	21	HIV	HIV	NNP
cord-032504-tmohg1mj	195	22	,	,	,
cord-032504-tmohg1mj	195	23	additional	additional	JJ
cord-032504-tmohg1mj	195	24	research	research	NN
cord-032504-tmohg1mj	195	25	is	be	VBZ
cord-032504-tmohg1mj	195	26	needed	need	VBN
cord-032504-tmohg1mj	195	27	to	to	TO
cord-032504-tmohg1mj	195	28	better	better	RB
cord-032504-tmohg1mj	195	29	understand	understand	VB
cord-032504-tmohg1mj	195	30	the	the	DT
cord-032504-tmohg1mj	195	31	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	195	32	and	and	CC
cord-032504-tmohg1mj	195	33	biological	biological	JJ
cord-032504-tmohg1mj	195	34	pathways	pathway	NNS
cord-032504-tmohg1mj	195	35	that	that	WDT
cord-032504-tmohg1mj	195	36	may	may	MD
cord-032504-tmohg1mj	195	37	be	be	VB
cord-032504-tmohg1mj	195	38	involved	involve	VBN
cord-032504-tmohg1mj	195	39	in	in	IN
cord-032504-tmohg1mj	195	40	facilitating	facilitate	VBG
cord-032504-tmohg1mj	195	41	mycobacterial	mycobacterial	JJ
cord-032504-tmohg1mj	195	42	immune	immune	JJ
cord-032504-tmohg1mj	195	43	evasion	evasion	NN
cord-032504-tmohg1mj	195	44	.	.	.
cord-032504-tmohg1mj	196	1	A	a	DT
cord-032504-tmohg1mj	196	2	greater	great	JJR
cord-032504-tmohg1mj	196	3	understanding	understanding	NN
cord-032504-tmohg1mj	196	4	of	of	IN
cord-032504-tmohg1mj	196	5	the	the	DT
cord-032504-tmohg1mj	196	6	impact	impact	NN
cord-032504-tmohg1mj	196	7	of	of	IN
cord-032504-tmohg1mj	196	8	HIV	HIV	NNP
cord-032504-tmohg1mj	196	9	on	on	IN
cord-032504-tmohg1mj	196	10	these	these	DT
cord-032504-tmohg1mj	196	11	earliest	early	JJS
cord-032504-tmohg1mj	196	12	responses	response	NNS
cord-032504-tmohg1mj	196	13	to	to	IN
cord-032504-tmohg1mj	196	14	Mtb	Mtb	NNP
cord-032504-tmohg1mj	196	15	may	may	MD
cord-032504-tmohg1mj	196	16	lead	lead	VB
cord-032504-tmohg1mj	196	17	to	to	IN
cord-032504-tmohg1mj	196	18	the	the	DT
cord-032504-tmohg1mj	196	19	development	development	NN
cord-032504-tmohg1mj	196	20	of	of	IN
cord-032504-tmohg1mj	196	21	novel	novel	JJ
cord-032504-tmohg1mj	196	22	interventions	intervention	NNS
cord-032504-tmohg1mj	196	23	and	and	CC
cord-032504-tmohg1mj	196	24	hostdirected	hostdirecte	VBN
cord-032504-tmohg1mj	196	25	therapies	therapy	NNS
cord-032504-tmohg1mj	196	26	to	to	TO
cord-032504-tmohg1mj	196	27	reduce	reduce	VB
cord-032504-tmohg1mj	196	28	the	the	DT
cord-032504-tmohg1mj	196	29	persistent	persistent	JJ
cord-032504-tmohg1mj	196	30	global	global	JJ
cord-032504-tmohg1mj	196	31	burden	burden	NN
cord-032504-tmohg1mj	196	32	of	of	IN
cord-032504-tmohg1mj	196	33	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	196	34	in	in	IN
cord-032504-tmohg1mj	196	35	this	this	DT
cord-032504-tmohg1mj	196	36	vulnerable	vulnerable	JJ
cord-032504-tmohg1mj	196	37	population	population	NN
cord-032504-tmohg1mj	196	38	.	.	.
cord-032504-tmohg1mj	197	1	Treatment	treatment	NN
cord-032504-tmohg1mj	197	2	of	of	IN
cord-032504-tmohg1mj	197	3	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	197	4	.	.	.
cord-032504-tmohg1mj	198	1	A	a	DT
cord-032504-tmohg1mj	198	2	historical	historical	JJ
cord-032504-tmohg1mj	198	3	perspective	perspective	NN
cord-032504-tmohg1mj	198	4	Directly	directly	RB
cord-032504-tmohg1mj	198	5	observed	observe	VBD
cord-032504-tmohg1mj	198	6	therapy	therapy	NN
cord-032504-tmohg1mj	198	7	for	for	IN
cord-032504-tmohg1mj	198	8	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	198	9	:	:	:
cord-032504-tmohg1mj	199	1	history	history	NN
cord-032504-tmohg1mj	199	2	of	of	IN
cord-032504-tmohg1mj	199	3	an	an	DT
cord-032504-tmohg1mj	199	4	idea	idea	NN
cord-032504-tmohg1mj	200	1	Principles	principle	NNS
cord-032504-tmohg1mj	200	2	of	of	IN
cord-032504-tmohg1mj	200	3	IUATLD	IUATLD	NNP
cord-032504-tmohg1mj	200	4	collaborative	collaborative	JJ
cord-032504-tmohg1mj	200	5	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	200	6	progammes	progamme	VBZ
cord-032504-tmohg1mj	200	7	Tuberculosis	Tuberculosis	NNP
cord-032504-tmohg1mj	200	8	therapy	therapy	NN
cord-032504-tmohg1mj	200	9	:	:	:
cord-032504-tmohg1mj	200	10	past	past	JJ
cord-032504-tmohg1mj	200	11	,	,	,
cord-032504-tmohg1mj	200	12	present	present	JJ
cord-032504-tmohg1mj	200	13	and	and	CC
cord-032504-tmohg1mj	200	14	future	future	JJ
cord-032504-tmohg1mj	200	15	Pneumocystis	Pneumocystis	NNP
cord-032504-tmohg1mj	200	16	pneumonia	pneumonia	NN
cord-032504-tmohg1mj	200	17	-	-	:
cord-032504-tmohg1mj	200	18	Los	Los	NNP
cord-032504-tmohg1mj	200	19	Angeles	Angeles	NNP
cord-032504-tmohg1mj	200	20	HIV	HIV	NNP
cord-032504-tmohg1mj	200	21	and	and	CC
cord-032504-tmohg1mj	200	22	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	200	23	:	:	:
cord-032504-tmohg1mj	200	24	a	a	DT
cord-032504-tmohg1mj	200	25	deadly	deadly	JJ
cord-032504-tmohg1mj	200	26	human	human	JJ
cord-032504-tmohg1mj	200	27	syndemic	syndemic	NN
cord-032504-tmohg1mj	201	1	The	the	DT
cord-032504-tmohg1mj	201	2	importance	importance	NN
cord-032504-tmohg1mj	201	3	of	of	IN
cord-032504-tmohg1mj	201	4	first	first	JJ
cord-032504-tmohg1mj	201	5	impressions	impression	NNS
cord-032504-tmohg1mj	201	6	:	:	:
cord-032504-tmohg1mj	202	1	early	early	JJ
cord-032504-tmohg1mj	202	2	events	event	NNS
cord-032504-tmohg1mj	202	3	in	in	IN
cord-032504-tmohg1mj	202	4	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	202	5	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	202	6	infection	infection	NN
cord-032504-tmohg1mj	202	7	influence	influence	NN
cord-032504-tmohg1mj	202	8	outcome	outcome	NN
cord-032504-tmohg1mj	203	1	The	the	DT
cord-032504-tmohg1mj	203	2	risk	risk	NN
cord-032504-tmohg1mj	203	3	of	of	IN
cord-032504-tmohg1mj	203	4	disease	disease	NN
cord-032504-tmohg1mj	203	5	progression	progression	NN
cord-032504-tmohg1mj	203	6	is	be	VBZ
cord-032504-tmohg1mj	203	7	determined	determine	VBN
cord-032504-tmohg1mj	203	8	during	during	IN
cord-032504-tmohg1mj	203	9	the	the	DT
cord-032504-tmohg1mj	203	10	first	first	JJ
cord-032504-tmohg1mj	203	11	year	year	NN
cord-032504-tmohg1mj	203	12	of	of	IN
cord-032504-tmohg1mj	203	13	human	human	JJ
cord-032504-tmohg1mj	203	14	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	203	15	virus	virus	NN
cord-032504-tmohg1mj	203	16	type	type	NN
cord-032504-tmohg1mj	203	17	1	1	CD
cord-032504-tmohg1mj	203	18	infection	infection	NN
cord-032504-tmohg1mj	203	19	Initial	initial	JJ
cord-032504-tmohg1mj	203	20	plasma	plasma	NN
cord-032504-tmohg1mj	203	21	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	203	22	RNA	RNA	NNP
cord-032504-tmohg1mj	203	23	levels	level	NNS
cord-032504-tmohg1mj	203	24	and	and	CC
cord-032504-tmohg1mj	203	25	progression	progression	NN
cord-032504-tmohg1mj	203	26	to	to	IN
cord-032504-tmohg1mj	203	27	AIDS	AIDS	NNP
cord-032504-tmohg1mj	203	28	in	in	IN
cord-032504-tmohg1mj	203	29	women	woman	NNS
cord-032504-tmohg1mj	203	30	and	and	CC
cord-032504-tmohg1mj	203	31	men	man	NNS
cord-032504-tmohg1mj	204	1	A	a	DT
cord-032504-tmohg1mj	204	2	whole	whole	JJ
cord-032504-tmohg1mj	204	3	-	-	HYPH
cord-032504-tmohg1mj	204	4	genome	genome	NN
cord-032504-tmohg1mj	204	5	association	association	NN
cord-032504-tmohg1mj	204	6	study	study	NN
cord-032504-tmohg1mj	204	7	of	of	IN
cord-032504-tmohg1mj	204	8	major	major	JJ
cord-032504-tmohg1mj	204	9	determinants	determinant	NNS
cord-032504-tmohg1mj	204	10	for	for	IN
cord-032504-tmohg1mj	204	11	host	host	NN
cord-032504-tmohg1mj	204	12	control	control	NN
cord-032504-tmohg1mj	204	13	of	of	IN
cord-032504-tmohg1mj	204	14	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	204	15	Host	Host	NNP
cord-032504-tmohg1mj	204	16	genetic	genetic	JJ
cord-032504-tmohg1mj	204	17	and	and	CC
cord-032504-tmohg1mj	204	18	viral	viral	JJ
cord-032504-tmohg1mj	204	19	determinants	determinant	NNS
cord-032504-tmohg1mj	204	20	of	of	IN
cord-032504-tmohg1mj	204	21	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	204	22	RNA	RNA	NNP
cord-032504-tmohg1mj	204	23	set	set	VBN
cord-032504-tmohg1mj	204	24	point	point	NN
cord-032504-tmohg1mj	204	25	among	among	IN
cord-032504-tmohg1mj	204	26	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	204	27	seroconverters	seroconverter	NNS
cord-032504-tmohg1mj	204	28	from	from	IN
cord-032504-tmohg1mj	204	29	Sub	Sub	NNP
cord-032504-tmohg1mj	204	30	-	-	HYPH
cord-032504-tmohg1mj	204	31	Saharan	Saharan	NNP
cord-032504-tmohg1mj	204	32	Africa	Africa	NNP
cord-032504-tmohg1mj	204	33	Estimating	estimate	VBG
cord-032504-tmohg1mj	204	34	the	the	DT
cord-032504-tmohg1mj	204	35	respective	respective	JJ
cord-032504-tmohg1mj	204	36	contributions	contribution	NNS
cord-032504-tmohg1mj	204	37	of	of	IN
cord-032504-tmohg1mj	204	38	human	human	JJ
cord-032504-tmohg1mj	204	39	and	and	CC
cord-032504-tmohg1mj	204	40	viral	viral	JJ
cord-032504-tmohg1mj	204	41	genetic	genetic	JJ
cord-032504-tmohg1mj	204	42	variation	variation	NN
cord-032504-tmohg1mj	204	43	to	to	IN
cord-032504-tmohg1mj	204	44	HIV	HIV	NNP
cord-032504-tmohg1mj	204	45	control	control	NN
cord-032504-tmohg1mj	204	46	Beyond	beyond	IN
cord-032504-tmohg1mj	204	47	macrophages	macrophage	NNS
cord-032504-tmohg1mj	204	48	:	:	:
cord-032504-tmohg1mj	204	49	the	the	DT
cord-032504-tmohg1mj	204	50	diversity	diversity	NN
cord-032504-tmohg1mj	204	51	of	of	IN
cord-032504-tmohg1mj	204	52	mononuclear	mononuclear	JJ
cord-032504-tmohg1mj	204	53	cells	cell	NNS
cord-032504-tmohg1mj	204	54	in	in	IN
cord-032504-tmohg1mj	204	55	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	204	56	Alveolar	alveolar	NN
cord-032504-tmohg1mj	204	57	macrophages	macrophage	NNS
cord-032504-tmohg1mj	204	58	provide	provide	VBP
cord-032504-tmohg1mj	204	59	an	an	DT
cord-032504-tmohg1mj	204	60	early	early	JJ
cord-032504-tmohg1mj	204	61	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	204	62	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	204	63	niche	niche	NN
cord-032504-tmohg1mj	204	64	and	and	CC
cord-032504-tmohg1mj	204	65	initiate	initiate	VB
cord-032504-tmohg1mj	204	66	dissemination	dissemination	NN
cord-032504-tmohg1mj	204	67	Mechanisms	mechanism	NNS
cord-032504-tmohg1mj	204	68	of	of	IN
cord-032504-tmohg1mj	204	69	M.	M.	NNP
cord-032504-tmohg1mj	204	70	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	204	71	immune	immune	JJ
cord-032504-tmohg1mj	204	72	evasion	evasion	NN
cord-032504-tmohg1mj	204	73	as	as	IN
cord-032504-tmohg1mj	204	74	challenges	challenge	NNS
cord-032504-tmohg1mj	204	75	to	to	IN
cord-032504-tmohg1mj	204	76	TB	TB	NNP
cord-032504-tmohg1mj	204	77	vaccine	vaccine	NN
cord-032504-tmohg1mj	205	1	design	design	NN
cord-032504-tmohg1mj	205	2	Pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	205	3	innate	innate	JJ
cord-032504-tmohg1mj	205	4	immune	immune	JJ
cord-032504-tmohg1mj	205	5	dysfunction	dysfunction	NN
cord-032504-tmohg1mj	205	6	in	in	IN
cord-032504-tmohg1mj	205	7	human	human	JJ
cord-032504-tmohg1mj	205	8	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	205	9	virus	virus	NN
cord-032504-tmohg1mj	205	10	Centers	Centers	NNPS
cord-032504-tmohg1mj	205	11	for	for	IN
cord-032504-tmohg1mj	205	12	Disease	Disease	NNP
cord-032504-tmohg1mj	205	13	Control	Control	NNP
cord-032504-tmohg1mj	205	14	and	and	CC
cord-032504-tmohg1mj	205	15	Prevention	Prevention	NNP
cord-032504-tmohg1mj	205	16	.	.	.
cord-032504-tmohg1mj	206	1	Multidrug	multidrug	JJ
cord-032504-tmohg1mj	206	2	-	-	HYPH
cord-032504-tmohg1mj	206	3	resistant	resistant	JJ
cord-032504-tmohg1mj	206	4	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	206	5	outbreak	outbreak	NN
cord-032504-tmohg1mj	206	6	on	on	IN
cord-032504-tmohg1mj	206	7	an	an	DT
cord-032504-tmohg1mj	206	8	HIV	HIV	NNP
cord-032504-tmohg1mj	206	9	Nosocomial	Nosocomial	NNP
cord-032504-tmohg1mj	206	10	transmission	transmission	NN
cord-032504-tmohg1mj	206	11	of	of	IN
cord-032504-tmohg1mj	206	12	multidrug	multidrug	NN
cord-032504-tmohg1mj	206	13	-	-	HYPH
cord-032504-tmohg1mj	206	14	resistant	resistant	JJ
cord-032504-tmohg1mj	206	15	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	206	16	among	among	IN
cord-032504-tmohg1mj	206	17	HIV	HIV	NNP
cord-032504-tmohg1mj	206	18	-	-	HYPH
cord-032504-tmohg1mj	206	19	infected	infect	VBN
cord-032504-tmohg1mj	206	20	persons-	persons-	NNP
cord-032504-tmohg1mj	207	1	Florida	Florida	NNP
cord-032504-tmohg1mj	208	1	An	an	DT
cord-032504-tmohg1mj	208	2	outbreak	outbreak	NN
cord-032504-tmohg1mj	208	3	of	of	IN
cord-032504-tmohg1mj	208	4	multidrug	multidrug	NN
cord-032504-tmohg1mj	208	5	-	-	HYPH
cord-032504-tmohg1mj	208	6	resistant	resistant	JJ
cord-032504-tmohg1mj	208	7	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	208	8	involving	involve	VBG
cord-032504-tmohg1mj	208	9	HIV	HIV	NNP
cord-032504-tmohg1mj	208	10	-	-	HYPH
cord-032504-tmohg1mj	208	11	infected	infect	VBN
cord-032504-tmohg1mj	208	12	patients	patient	NNS
cord-032504-tmohg1mj	208	13	of	of	IN
cord-032504-tmohg1mj	208	14	two	two	CD
cord-032504-tmohg1mj	208	15	hospitals	hospital	NNS
cord-032504-tmohg1mj	208	16	in	in	IN
cord-032504-tmohg1mj	208	17	Milan	Milan	NNP
cord-032504-tmohg1mj	208	18	,	,	,
cord-032504-tmohg1mj	208	19	Italy	Italy	NNP
cord-032504-tmohg1mj	208	20	.	.	.
cord-032504-tmohg1mj	209	1	Italian	Italian	NNP
cord-032504-tmohg1mj	209	2	Multidrug	Multidrug	NNP
cord-032504-tmohg1mj	209	3	-	-	HYPH
cord-032504-tmohg1mj	209	4	Resistant	Resistant	NNP
cord-032504-tmohg1mj	209	5	Tuberculosis	Tuberculosis	NNP
cord-032504-tmohg1mj	209	6	Outbreak	Outbreak	NNP
cord-032504-tmohg1mj	209	7	Study	Study	NNP
cord-032504-tmohg1mj	209	8	Group	Group	NNP
cord-032504-tmohg1mj	210	1	How	how	WRB
cord-032504-tmohg1mj	210	2	soon	soon	RB
cord-032504-tmohg1mj	210	3	after	after	IN
cord-032504-tmohg1mj	210	4	infection	infection	NN
cord-032504-tmohg1mj	210	5	with	with	IN
cord-032504-tmohg1mj	210	6	HIV	HIV	NNP
cord-032504-tmohg1mj	210	7	does	do	VBZ
cord-032504-tmohg1mj	210	8	the	the	DT
cord-032504-tmohg1mj	210	9	risk	risk	NN
cord-032504-tmohg1mj	210	10	of	of	IN
cord-032504-tmohg1mj	210	11	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	210	12	start	start	VBP
cord-032504-tmohg1mj	210	13	to	to	TO
cord-032504-tmohg1mj	210	14	increase	increase	VB
cord-032504-tmohg1mj	210	15	?	?	.
cord-032504-tmohg1mj	211	1	A	a	DT
cord-032504-tmohg1mj	211	2	retrospective	retrospective	JJ
cord-032504-tmohg1mj	211	3	cohort	cohort	NN
cord-032504-tmohg1mj	211	4	study	study	NN
cord-032504-tmohg1mj	211	5	in	in	IN
cord-032504-tmohg1mj	211	6	South	south	JJ
cord-032504-tmohg1mj	211	7	African	african	JJ
cord-032504-tmohg1mj	211	8	gold	gold	NN
cord-032504-tmohg1mj	211	9	miners	miner	NNS
cord-032504-tmohg1mj	211	10	Tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	211	11	incidence	incidence	NN
cord-032504-tmohg1mj	211	12	rates	rate	NNS
cord-032504-tmohg1mj	211	13	during	during	IN
cord-032504-tmohg1mj	211	14	8	8	CD
cord-032504-tmohg1mj	211	15	years	year	NNS
cord-032504-tmohg1mj	211	16	of	of	IN
cord-032504-tmohg1mj	211	17	follow	follow	NN
cord-032504-tmohg1mj	211	18	-	-	HYPH
cord-032504-tmohg1mj	211	19	up	up	NN
cord-032504-tmohg1mj	211	20	of	of	IN
cord-032504-tmohg1mj	211	21	an	an	DT
cord-032504-tmohg1mj	211	22	antiretroviral	antiretroviral	JJ
cord-032504-tmohg1mj	211	23	treatment	treatment	NN
cord-032504-tmohg1mj	211	24	cohort	cohort	NN
cord-032504-tmohg1mj	211	25	in	in	IN
cord-032504-tmohg1mj	211	26	South	South	NNP
cord-032504-tmohg1mj	211	27	Africa	Africa	NNP
cord-032504-tmohg1mj	211	28	:	:	:
cord-032504-tmohg1mj	211	29	comparison	comparison	NN
cord-032504-tmohg1mj	211	30	with	with	IN
cord-032504-tmohg1mj	211	31	rates	rate	NNS
cord-032504-tmohg1mj	211	32	in	in	IN
cord-032504-tmohg1mj	211	33	the	the	DT
cord-032504-tmohg1mj	211	34	community	community	NN
cord-032504-tmohg1mj	211	35	Tuberculosis	Tuberculosis	NNP
cord-032504-tmohg1mj	211	36	in	in	IN
cord-032504-tmohg1mj	211	37	HIV	HIV	NNP
cord-032504-tmohg1mj	211	38	-	-	HYPH
cord-032504-tmohg1mj	211	39	infected	infect	VBN
cord-032504-tmohg1mj	211	40	persons	person	NNS
cord-032504-tmohg1mj	211	41	in	in	IN
cord-032504-tmohg1mj	211	42	the	the	DT
cord-032504-tmohg1mj	211	43	context	context	NN
cord-032504-tmohg1mj	211	44	of	of	IN
cord-032504-tmohg1mj	211	45	wide	wide	JJ
cord-032504-tmohg1mj	211	46	availability	availability	NN
cord-032504-tmohg1mj	211	47	of	of	IN
cord-032504-tmohg1mj	211	48	highly	highly	RB
cord-032504-tmohg1mj	211	49	active	active	JJ
cord-032504-tmohg1mj	211	50	antiretroviral	antiretroviral	JJ
cord-032504-tmohg1mj	211	51	therapy	therapy	NN
cord-032504-tmohg1mj	211	52	Animal	Animal	NNP
cord-032504-tmohg1mj	211	53	models	model	NNS
cord-032504-tmohg1mj	211	54	of	of	IN
cord-032504-tmohg1mj	211	55	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	211	56	:	:	:
cord-032504-tmohg1mj	211	57	an	an	DT
cord-032504-tmohg1mj	211	58	overview	overview	NN
cord-032504-tmohg1mj	211	59	Animal	Animal	NNP
cord-032504-tmohg1mj	211	60	models	model	NNS
cord-032504-tmohg1mj	211	61	of	of	IN
cord-032504-tmohg1mj	211	62	cavitation	cavitation	NN
cord-032504-tmohg1mj	211	63	in	in	IN
cord-032504-tmohg1mj	211	64	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	211	65	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	211	66	Killing	kill	VBG
cord-032504-tmohg1mj	211	67	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	211	68	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	211	69	in	in	IN
cord-032504-tmohg1mj	211	70	vitro	vitro	FW
cord-032504-tmohg1mj	211	71	:	:	:
cord-032504-tmohg1mj	211	72	what	what	WDT
cord-032504-tmohg1mj	211	73	model	model	NN
cord-032504-tmohg1mj	211	74	systems	system	NNS
cord-032504-tmohg1mj	211	75	can	can	MD
cord-032504-tmohg1mj	211	76	teach	teach	VB
cord-032504-tmohg1mj	211	77	us	-PRON-	PRP
cord-032504-tmohg1mj	211	78	Nitric	nitric	NN
cord-032504-tmohg1mj	211	79	oxide	oxide	NN
cord-032504-tmohg1mj	211	80	synthase	synthase	NN
cord-032504-tmohg1mj	211	81	in	in	IN
cord-032504-tmohg1mj	211	82	innate	innate	JJ
cord-032504-tmohg1mj	211	83	and	and	CC
cord-032504-tmohg1mj	211	84	adaptive	adaptive	JJ
cord-032504-tmohg1mj	211	85	immunity	immunity	NN
cord-032504-tmohg1mj	211	86	:	:	:
cord-032504-tmohg1mj	211	87	an	an	DT
cord-032504-tmohg1mj	211	88	update	update	NN
cord-032504-tmohg1mj	211	89	Large	large	JJ
cord-032504-tmohg1mj	211	90	scale	scale	NN
cord-032504-tmohg1mj	211	91	comparison	comparison	NN
cord-032504-tmohg1mj	211	92	of	of	IN
cord-032504-tmohg1mj	211	93	innate	innate	JJ
cord-032504-tmohg1mj	211	94	responses	response	NNS
cord-032504-tmohg1mj	211	95	to	to	IN
cord-032504-tmohg1mj	211	96	viral	viral	JJ
cord-032504-tmohg1mj	211	97	and	and	CC
cord-032504-tmohg1mj	211	98	bacterial	bacterial	JJ
cord-032504-tmohg1mj	211	99	pathogens	pathogen	NNS
cord-032504-tmohg1mj	211	100	in	in	IN
cord-032504-tmohg1mj	211	101	mouse	mouse	NN
cord-032504-tmohg1mj	211	102	and	and	CC
cord-032504-tmohg1mj	211	103	macaque	macaque	NN
cord-032504-tmohg1mj	212	1	Tissue	tissue	NN
cord-032504-tmohg1mj	212	2	-	-	HYPH
cord-032504-tmohg1mj	212	3	resident	resident	NN
cord-032504-tmohg1mj	212	4	macrophage	macrophage	NN
cord-032504-tmohg1mj	212	5	ontogeny	ontogeny	NN
cord-032504-tmohg1mj	212	6	and	and	CC
cord-032504-tmohg1mj	212	7	homeostasis	homeostasis	NN
cord-032504-tmohg1mj	212	8	Macrophage	Macrophage	NNP
cord-032504-tmohg1mj	212	9	activation	activation	NN
cord-032504-tmohg1mj	212	10	and	and	CC
cord-032504-tmohg1mj	212	11	polarization	polarization	NN
cord-032504-tmohg1mj	212	12	:	:	:
cord-032504-tmohg1mj	212	13	nomenclature	nomenclature	NN
cord-032504-tmohg1mj	212	14	and	and	CC
cord-032504-tmohg1mj	212	15	experimental	experimental	JJ
cord-032504-tmohg1mj	212	16	guidelines	guideline	NNS
cord-032504-tmohg1mj	212	17	Macrophage	Macrophage	NNP
cord-032504-tmohg1mj	212	18	heterogeneity	heterogeneity	NN
cord-032504-tmohg1mj	212	19	in	in	IN
cord-032504-tmohg1mj	212	20	tissues	tissue	NNS
cord-032504-tmohg1mj	212	21	:	:	:
cord-032504-tmohg1mj	212	22	phenotypic	phenotypic	JJ
cord-032504-tmohg1mj	212	23	diversity	diversity	NN
cord-032504-tmohg1mj	212	24	and	and	CC
cord-032504-tmohg1mj	212	25	functions	function	NNS
cord-032504-tmohg1mj	212	26	Differential	differential	JJ
cord-032504-tmohg1mj	212	27	polarization	polarization	NN
cord-032504-tmohg1mj	212	28	of	of	IN
cord-032504-tmohg1mj	212	29	alveolar	alveolar	JJ
cord-032504-tmohg1mj	212	30	macrophages	macrophage	NNS
cord-032504-tmohg1mj	212	31	and	and	CC
cord-032504-tmohg1mj	212	32	bone	bone	NN
cord-032504-tmohg1mj	212	33	marrow	marrow	NN
cord-032504-tmohg1mj	212	34	-	-	HYPH
cord-032504-tmohg1mj	212	35	derived	derive	VBN
cord-032504-tmohg1mj	212	36	monocytes	monocyte	NNS
cord-032504-tmohg1mj	212	37	following	follow	VBG
cord-032504-tmohg1mj	212	38	chemically	chemically	RB
cord-032504-tmohg1mj	212	39	and	and	CC
cord-032504-tmohg1mj	212	40	pathogeninduced	pathogeninduced	JJ
cord-032504-tmohg1mj	212	41	chronic	chronic	JJ
cord-032504-tmohg1mj	212	42	lung	lung	NN
cord-032504-tmohg1mj	212	43	inflammation	inflammation	NN
cord-032504-tmohg1mj	212	44	Human	human	JJ
cord-032504-tmohg1mj	212	45	lung	lung	NN
cord-032504-tmohg1mj	212	46	immunity	immunity	NN
cord-032504-tmohg1mj	212	47	against	against	IN
cord-032504-tmohg1mj	212	48	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	212	49	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	212	50	:	:	:
cord-032504-tmohg1mj	212	51	insights	insight	NNS
cord-032504-tmohg1mj	212	52	into	into	IN
cord-032504-tmohg1mj	212	53	pathogenesis	pathogenesis	NN
cord-032504-tmohg1mj	212	54	and	and	CC
cord-032504-tmohg1mj	212	55	protection	protection	NN
cord-032504-tmohg1mj	212	56	The	the	DT
cord-032504-tmohg1mj	212	57	zebrafish	zebrafish	NN
cord-032504-tmohg1mj	212	58	model	model	NN
cord-032504-tmohg1mj	212	59	of	of	IN
cord-032504-tmohg1mj	212	60	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	212	61	-	-	:
cord-032504-tmohg1mj	212	62	no	no	DT
cord-032504-tmohg1mj	212	63	lungs	lung	NNS
cord-032504-tmohg1mj	213	1	needed	need	VBN
cord-032504-tmohg1mj	213	2	Mouse	Mouse	NNP
cord-032504-tmohg1mj	213	3	model	model	NN
cord-032504-tmohg1mj	213	4	of	of	IN
cord-032504-tmohg1mj	213	5	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	213	6	Animal	Animal	NNP
cord-032504-tmohg1mj	213	7	models	model	NNS
cord-032504-tmohg1mj	213	8	of	of	IN
cord-032504-tmohg1mj	213	9	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	213	10	:	:	:
cord-032504-tmohg1mj	214	1	lesson	lesson	NN
cord-032504-tmohg1mj	214	2	learnt	learn	VBN
cord-032504-tmohg1mj	214	3	Anti	anti	JJ
cord-032504-tmohg1mj	214	4	-	-	JJ
cord-032504-tmohg1mj	214	5	vascular	vascular	JJ
cord-032504-tmohg1mj	214	6	endothelial	endothelial	JJ
cord-032504-tmohg1mj	214	7	growth	growth	NN
cord-032504-tmohg1mj	214	8	factor	factor	NN
cord-032504-tmohg1mj	214	9	treatment	treatment	NN
cord-032504-tmohg1mj	214	10	normalizes	normalize	VBZ
cord-032504-tmohg1mj	214	11	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	214	12	granuloma	granuloma	NN
cord-032504-tmohg1mj	214	13	vasculature	vasculature	NN
cord-032504-tmohg1mj	214	14	and	and	CC
cord-032504-tmohg1mj	214	15	improves	improve	VBZ
cord-032504-tmohg1mj	214	16	small	small	JJ
cord-032504-tmohg1mj	214	17	molecule	molecule	NN
cord-032504-tmohg1mj	214	18	delivery	delivery	NN
cord-032504-tmohg1mj	214	19	Prevention	Prevention	NNP
cord-032504-tmohg1mj	214	20	of	of	IN
cord-032504-tmohg1mj	214	21	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	214	22	in	in	IN
cord-032504-tmohg1mj	214	23	macaques	macaque	NNS
cord-032504-tmohg1mj	214	24	after	after	IN
cord-032504-tmohg1mj	214	25	intravenous	intravenous	JJ
cord-032504-tmohg1mj	214	26	BCG	BCG	NNP
cord-032504-tmohg1mj	214	27	immunization	immunization	NN
cord-032504-tmohg1mj	214	28	Monkey	Monkey	NNP
cord-032504-tmohg1mj	214	29	models	model	NNS
cord-032504-tmohg1mj	214	30	of	of	IN
cord-032504-tmohg1mj	214	31	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	214	32	:	:	:
cord-032504-tmohg1mj	214	33	lessons	lesson	NNS
cord-032504-tmohg1mj	214	34	learned	learn	VBD
cord-032504-tmohg1mj	214	35	Some	some	DT
cord-032504-tmohg1mj	214	36	clinical	clinical	JJ
cord-032504-tmohg1mj	214	37	features	feature	NNS
cord-032504-tmohg1mj	214	38	of	of	IN
cord-032504-tmohg1mj	214	39	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	214	40	.	.	.
cord-032504-tmohg1mj	215	1	1	1	LS
cord-032504-tmohg1mj	215	2	.	.	.
cord-032504-tmohg1mj	216	1	Incubation	incubation	NN
cord-032504-tmohg1mj	216	2	period	period	NN
cord-032504-tmohg1mj	216	3	Tuberculous	tuberculous	JJ
cord-032504-tmohg1mj	216	4	infection	infection	NN
cord-032504-tmohg1mj	216	5	in	in	IN
cord-032504-tmohg1mj	216	6	the	the	DT
cord-032504-tmohg1mj	216	7	light	light	NN
cord-032504-tmohg1mj	216	8	of	of	IN
cord-032504-tmohg1mj	216	9	tuberculin	tuberculin	NN
cord-032504-tmohg1mj	216	10	matriculation	matriculation	NN
cord-032504-tmohg1mj	217	1	The	the	DT
cord-032504-tmohg1mj	217	2	time	time	NN
cord-032504-tmohg1mj	217	3	-	-	HYPH
cord-032504-tmohg1mj	217	4	table	table	NN
cord-032504-tmohg1mj	217	5	of	of	IN
cord-032504-tmohg1mj	217	6	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	217	7	Resistance	resistance	NN
cord-032504-tmohg1mj	217	8	to	to	IN
cord-032504-tmohg1mj	217	9	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	217	10	:	:	:
cord-032504-tmohg1mj	217	11	experimental	experimental	JJ
cord-032504-tmohg1mj	217	12	studies	study	NNS
cord-032504-tmohg1mj	217	13	in	in	IN
cord-032504-tmohg1mj	217	14	native	native	JJ
cord-032504-tmohg1mj	217	15	and	and	CC
cord-032504-tmohg1mj	217	16	acquired	acquire	VBN
cord-032504-tmohg1mj	217	17	defensive	defensive	JJ
cord-032504-tmohg1mj	217	18	mechanism	mechanism	NN
cord-032504-tmohg1mj	217	19	Animal	Animal	NNP
cord-032504-tmohg1mj	217	20	model	model	NN
cord-032504-tmohg1mj	217	21	:	:	:
cord-032504-tmohg1mj	217	22	experimental	experimental	JJ
cord-032504-tmohg1mj	217	23	airborne	airborne	JJ
cord-032504-tmohg1mj	217	24	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	217	25	in	in	IN
cord-032504-tmohg1mj	217	26	the	the	DT
cord-032504-tmohg1mj	217	27	guinea	guinea	NN
cord-032504-tmohg1mj	217	28	pig	pig	NN
cord-032504-tmohg1mj	217	29	Initiation	Initiation	NNP
cord-032504-tmohg1mj	217	30	of	of	IN
cord-032504-tmohg1mj	217	31	the	the	DT
cord-032504-tmohg1mj	217	32	adaptive	adaptive	JJ
cord-032504-tmohg1mj	217	33	immune	immune	JJ
cord-032504-tmohg1mj	217	34	response	response	NN
cord-032504-tmohg1mj	217	35	to	to	IN
cord-032504-tmohg1mj	217	36	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	217	37	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	217	38	depends	depend	VBZ
cord-032504-tmohg1mj	217	39	on	on	IN
cord-032504-tmohg1mj	217	40	antigen	antigen	NN
cord-032504-tmohg1mj	217	41	production	production	NN
cord-032504-tmohg1mj	217	42	in	in	IN
cord-032504-tmohg1mj	217	43	the	the	DT
cord-032504-tmohg1mj	217	44	local	local	JJ
cord-032504-tmohg1mj	217	45	lymph	lymph	NN
cord-032504-tmohg1mj	217	46	node	node	NN
cord-032504-tmohg1mj	217	47	,	,	,
cord-032504-tmohg1mj	217	48	not	not	RB
cord-032504-tmohg1mj	217	49	the	the	DT
cord-032504-tmohg1mj	217	50	lungs	lung	NNS
cord-032504-tmohg1mj	217	51	Delayed	delay	VBN
cord-032504-tmohg1mj	217	52	-	-	HYPH
cord-032504-tmohg1mj	217	53	type	type	NN
cord-032504-tmohg1mj	217	54	hypersensitivity	hypersensitivity	NN
cord-032504-tmohg1mj	217	55	and	and	CC
cord-032504-tmohg1mj	217	56	cell	cell	NN
cord-032504-tmohg1mj	217	57	-	-	HYPH
cord-032504-tmohg1mj	217	58	mediated	mediate	VBN
cord-032504-tmohg1mj	217	59	immunity	immunity	NN
cord-032504-tmohg1mj	217	60	in	in	IN
cord-032504-tmohg1mj	217	61	the	the	DT
cord-032504-tmohg1mj	217	62	pathogenesis	pathogenesis	NN
cord-032504-tmohg1mj	217	63	of	of	IN
cord-032504-tmohg1mj	217	64	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	217	65	Tracking	track	VBG
cord-032504-tmohg1mj	217	66	salmonella	salmonella	NN
cord-032504-tmohg1mj	217	67	-	-	HYPH
cord-032504-tmohg1mj	217	68	specific	specific	JJ
cord-032504-tmohg1mj	217	69	CD4	CD4	NNP
cord-032504-tmohg1mj	217	70	T	T	NNP
cord-032504-tmohg1mj	217	71	cells	cell	NNS
cord-032504-tmohg1mj	217	72	in	in	IN
cord-032504-tmohg1mj	217	73	vivo	vivo	NN
cord-032504-tmohg1mj	217	74	reveals	reveal	VBZ
cord-032504-tmohg1mj	217	75	a	a	DT
cord-032504-tmohg1mj	217	76	local	local	JJ
cord-032504-tmohg1mj	217	77	mucosal	mucosal	JJ
cord-032504-tmohg1mj	217	78	response	response	NN
cord-032504-tmohg1mj	217	79	to	to	IN
cord-032504-tmohg1mj	217	80	a	a	DT
cord-032504-tmohg1mj	217	81	disseminated	disseminate	VBN
cord-032504-tmohg1mj	217	82	infection	infection	NN
cord-032504-tmohg1mj	217	83	Organ	organ	NN
cord-032504-tmohg1mj	217	84	-	-	HYPH
cord-032504-tmohg1mj	217	85	specific	specific	JJ
cord-032504-tmohg1mj	217	86	CD4	CD4	NNP
cord-032504-tmohg1mj	217	87	+	+	CC
cord-032504-tmohg1mj	217	88	T	T	NNP
cord-032504-tmohg1mj	217	89	cell	cell	NN
cord-032504-tmohg1mj	217	90	response	response	NN
cord-032504-tmohg1mj	217	91	during	during	IN
cord-032504-tmohg1mj	217	92	Listeria	Listeria	NNP
cord-032504-tmohg1mj	217	93	monocytogenes	monocytogene	VBZ
cord-032504-tmohg1mj	217	94	infection	infection	NN
cord-032504-tmohg1mj	217	95	Progressive	progressive	JJ
cord-032504-tmohg1mj	217	96	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	217	97	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	217	98	is	be	VBZ
cord-032504-tmohg1mj	217	99	not	not	RB
cord-032504-tmohg1mj	217	100	due	due	JJ
cord-032504-tmohg1mj	217	101	to	to	IN
cord-032504-tmohg1mj	217	102	increasing	increase	VBG
cord-032504-tmohg1mj	217	103	numbers	number	NNS
cord-032504-tmohg1mj	217	104	of	of	IN
cord-032504-tmohg1mj	217	105	viable	viable	JJ
cord-032504-tmohg1mj	217	106	bacilli	bacilli	NN
cord-032504-tmohg1mj	217	107	in	in	IN
cord-032504-tmohg1mj	217	108	rabbits	rabbit	NNS
cord-032504-tmohg1mj	217	109	,	,	,
cord-032504-tmohg1mj	217	110	mice	mouse	NNS
cord-032504-tmohg1mj	217	111	and	and	CC
cord-032504-tmohg1mj	217	112	guinea	guinea	NN
cord-032504-tmohg1mj	217	113	pigs	pig	NNS
cord-032504-tmohg1mj	217	114	,	,	,
cord-032504-tmohg1mj	217	115	but	but	CC
cord-032504-tmohg1mj	217	116	is	be	VBZ
cord-032504-tmohg1mj	217	117	due	due	JJ
cord-032504-tmohg1mj	217	118	to	to	IN
cord-032504-tmohg1mj	217	119	a	a	DT
cord-032504-tmohg1mj	217	120	continuous	continuous	JJ
cord-032504-tmohg1mj	217	121	host	host	NN
cord-032504-tmohg1mj	217	122	response	response	NN
cord-032504-tmohg1mj	217	123	to	to	IN
cord-032504-tmohg1mj	217	124	mycobacterial	mycobacterial	NNP
cord-032504-tmohg1mj	217	125	products	product	NNS
cord-032504-tmohg1mj	218	1	Immunity	immunity	NN
cord-032504-tmohg1mj	218	2	to	to	IN
cord-032504-tmohg1mj	218	3	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	4	Experimental	Experimental	NNP
cord-032504-tmohg1mj	218	5	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	218	6	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	7	infection	infection	NN
cord-032504-tmohg1mj	218	8	of	of	IN
cord-032504-tmohg1mj	218	9	cynomolgus	cynomolgus	JJ
cord-032504-tmohg1mj	218	10	macaques	macaque	NNS
cord-032504-tmohg1mj	218	11	closely	closely	RB
cord-032504-tmohg1mj	218	12	resembles	resemble	VBZ
cord-032504-tmohg1mj	218	13	the	the	DT
cord-032504-tmohg1mj	218	14	various	various	JJ
cord-032504-tmohg1mj	218	15	manifestations	manifestation	NNS
cord-032504-tmohg1mj	218	16	of	of	IN
cord-032504-tmohg1mj	218	17	human	human	JJ
cord-032504-tmohg1mj	218	18	M.	M.	NNP
cord-032504-tmohg1mj	218	19	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	20	infection	infection	NN
cord-032504-tmohg1mj	218	21	Early	early	JJ
cord-032504-tmohg1mj	218	22	Changes	change	NNS
cord-032504-tmohg1mj	218	23	by	by	IN
cord-032504-tmohg1mj	218	24	(	(	-LRB-
cord-032504-tmohg1mj	218	25	18)Fluorodeoxyglucose	18)fluorodeoxyglucose	CD
cord-032504-tmohg1mj	218	26	positron	positron	NN
cord-032504-tmohg1mj	218	27	emission	emission	NN
cord-032504-tmohg1mj	218	28	tomography	tomography	NN
cord-032504-tmohg1mj	218	29	coregistered	coregistere	VBN
cord-032504-tmohg1mj	218	30	with	with	IN
cord-032504-tmohg1mj	218	31	computed	compute	VBN
cord-032504-tmohg1mj	218	32	tomography	tomography	NN
cord-032504-tmohg1mj	218	33	predict	predict	NN
cord-032504-tmohg1mj	218	34	outcome	outcome	NN
cord-032504-tmohg1mj	218	35	after	after	IN
cord-032504-tmohg1mj	218	36	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	218	37	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	38	infection	infection	NN
cord-032504-tmohg1mj	218	39	in	in	IN
cord-032504-tmohg1mj	218	40	cynomolgus	cynomolgus	JJ
cord-032504-tmohg1mj	218	41	macaques	macaque	NNS
cord-032504-tmohg1mj	218	42	Digitally	digitally	RB
cord-032504-tmohg1mj	218	43	barcoding	barcode	VBG
cord-032504-tmohg1mj	218	44	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	218	45	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	46	reveals	reveal	VBZ
cord-032504-tmohg1mj	218	47	in	in	IN
cord-032504-tmohg1mj	218	48	vivo	vivo	NN
cord-032504-tmohg1mj	218	49	infection	infection	NN
cord-032504-tmohg1mj	218	50	dynamics	dynamic	NNS
cord-032504-tmohg1mj	218	51	in	in	IN
cord-032504-tmohg1mj	218	52	the	the	DT
cord-032504-tmohg1mj	218	53	macaque	macaque	NN
cord-032504-tmohg1mj	218	54	model	model	NN
cord-032504-tmohg1mj	218	55	of	of	IN
cord-032504-tmohg1mj	218	56	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	57	Protective	protective	JJ
cord-032504-tmohg1mj	218	58	immunity	immunity	NN
cord-032504-tmohg1mj	218	59	against	against	IN
cord-032504-tmohg1mj	218	60	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	218	61	:	:	:
cord-032504-tmohg1mj	218	62	what	what	WP
cord-032504-tmohg1mj	218	63	does	do	VBZ
cord-032504-tmohg1mj	218	64	it	-PRON-	PRP
cord-032504-tmohg1mj	218	65	look	look	VB
cord-032504-tmohg1mj	218	66	like	like	IN
cord-032504-tmohg1mj	218	67	and	and	CC
cord-032504-tmohg1mj	218	68	how	how	WRB
cord-032504-tmohg1mj	218	69	do	do	VBP
cord-032504-tmohg1mj	218	70	we	-PRON-	PRP
cord-032504-tmohg1mj	218	71	find	find	VB
cord-032504-tmohg1mj	218	72	it	-PRON-	PRP
cord-032504-tmohg1mj	218	73	?	?	.
cord-032504-tmohg1mj	219	1	Intranasal	Intranasal	NNP
cord-032504-tmohg1mj	219	2	Poly	Poly	NNP
cord-032504-tmohg1mj	219	3	-	-	HYPH
cord-032504-tmohg1mj	219	4	IC	IC	NNP
cord-032504-tmohg1mj	219	5	treatment	treatment	NN
cord-032504-tmohg1mj	219	6	exacerbates	exacerbate	VBZ
cord-032504-tmohg1mj	219	7	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	219	8	in	in	IN
cord-032504-tmohg1mj	219	9	mice	mouse	NNS
cord-032504-tmohg1mj	219	10	through	through	IN
cord-032504-tmohg1mj	219	11	the	the	DT
cord-032504-tmohg1mj	219	12	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	219	13	recruitment	recruitment	NN
cord-032504-tmohg1mj	219	14	of	of	IN
cord-032504-tmohg1mj	219	15	a	a	DT
cord-032504-tmohg1mj	219	16	pathogen	pathogen	NN
cord-032504-tmohg1mj	219	17	-	-	HYPH
cord-032504-tmohg1mj	219	18	permissive	permissive	JJ
cord-032504-tmohg1mj	219	19	monocyte	monocyte	NNP
cord-032504-tmohg1mj	219	20	/	/	SYM
cord-032504-tmohg1mj	219	21	macrophage	macrophage	NN
cord-032504-tmohg1mj	219	22	population	population	NN
cord-032504-tmohg1mj	219	23	Macrophage	Macrophage	NNP
cord-032504-tmohg1mj	219	24	polarization	polarization	NN
cord-032504-tmohg1mj	219	25	drives	drive	VBZ
cord-032504-tmohg1mj	219	26	granuloma	granuloma	NN
cord-032504-tmohg1mj	219	27	outcome	outcome	NN
cord-032504-tmohg1mj	219	28	during	during	IN
cord-032504-tmohg1mj	219	29	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	219	30	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	219	31	infection	infection	NN
cord-032504-tmohg1mj	220	1	Healthy	healthy	JJ
cord-032504-tmohg1mj	220	2	HIV-1-infected	hiv-1-infecte	VBN
cord-032504-tmohg1mj	220	3	individuals	individual	NNS
cord-032504-tmohg1mj	220	4	on	on	IN
cord-032504-tmohg1mj	220	5	highly	highly	RB
cord-032504-tmohg1mj	220	6	active	active	JJ
cord-032504-tmohg1mj	220	7	antiretroviral	antiretroviral	JJ
cord-032504-tmohg1mj	220	8	therapy	therapy	NN
cord-032504-tmohg1mj	220	9	harbor	harbor	VBP
cord-032504-tmohg1mj	220	10	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	220	11	in	in	IN
cord-032504-tmohg1mj	220	12	their	-PRON-	PRP$
cord-032504-tmohg1mj	220	13	alveolar	alveolar	NN
cord-032504-tmohg1mj	220	14	macrophages	macrophage	NNS
cord-032504-tmohg1mj	220	15	Macrophage	macrophage	NN
cord-032504-tmohg1mj	220	16	polarization	polarization	NN
cord-032504-tmohg1mj	220	17	:	:	:
cord-032504-tmohg1mj	220	18	convergence	convergence	NN
cord-032504-tmohg1mj	220	19	point	point	NN
cord-032504-tmohg1mj	220	20	targeted	target	VBN
cord-032504-tmohg1mj	220	21	by	by	IN
cord-032504-tmohg1mj	220	22	mycobacterium	mycobacterium	NN
cord-032504-tmohg1mj	220	23	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	220	24	and	and	CC
cord-032504-tmohg1mj	220	25	HIV	HIV	NNP
cord-032504-tmohg1mj	221	1	The	the	DT
cord-032504-tmohg1mj	221	2	macrophage	macrophage	NN
cord-032504-tmohg1mj	221	3	in	in	IN
cord-032504-tmohg1mj	221	4	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	221	5	infection	infection	NN
cord-032504-tmohg1mj	221	6	:	:	:
cord-032504-tmohg1mj	221	7	from	from	IN
cord-032504-tmohg1mj	221	8	activation	activation	NN
cord-032504-tmohg1mj	221	9	to	to	IN
cord-032504-tmohg1mj	221	10	deactivation	deactivation	NN
cord-032504-tmohg1mj	221	11	?	?	.
cord-032504-tmohg1mj	222	1	Tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	222	2	exacerbates	exacerbate	VBZ
cord-032504-tmohg1mj	222	3	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	222	4	infection	infection	NN
cord-032504-tmohg1mj	222	5	through	through	IN
cord-032504-tmohg1mj	222	6	IL-10	IL-10	NNP
cord-032504-tmohg1mj	222	7	/	/	SYM
cord-032504-tmohg1mj	222	8	STAT3-dependent	STAT3-dependent	NNP
cord-032504-tmohg1mj	222	9	tunneling	tunnel	VBG
cord-032504-tmohg1mj	222	10	nanotube	nanotube	NN
cord-032504-tmohg1mj	222	11	formation	formation	NN
cord-032504-tmohg1mj	222	12	in	in	IN
cord-032504-tmohg1mj	222	13	macrophages	macrophage	NNS
cord-032504-tmohg1mj	223	1	High	high	JJ
cord-032504-tmohg1mj	223	2	turnover	turnover	NN
cord-032504-tmohg1mj	223	3	of	of	IN
cord-032504-tmohg1mj	223	4	tissue	tissue	NN
cord-032504-tmohg1mj	223	5	macrophages	macrophage	NNS
cord-032504-tmohg1mj	223	6	contributes	contribute	VBZ
cord-032504-tmohg1mj	223	7	to	to	IN
cord-032504-tmohg1mj	223	8	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	223	9	reactivation	reactivation	NN
cord-032504-tmohg1mj	223	10	in	in	IN
cord-032504-tmohg1mj	223	11	simian	simian	JJ
cord-032504-tmohg1mj	223	12	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	223	13	virus	virus	NN
cord-032504-tmohg1mj	223	14	-	-	HYPH
cord-032504-tmohg1mj	223	15	infected	infect	VBN
cord-032504-tmohg1mj	223	16	rhesus	rhesu	NNS
cord-032504-tmohg1mj	223	17	macaques	macaque	NNS
cord-032504-tmohg1mj	223	18	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	223	19	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	223	20	and	and	CC
cord-032504-tmohg1mj	223	21	HIV	HIV	NNP
cord-032504-tmohg1mj	223	22	coinfection	coinfection	NN
cord-032504-tmohg1mj	223	23	brings	bring	VBZ
cord-032504-tmohg1mj	223	24	fire	fire	NN
cord-032504-tmohg1mj	223	25	and	and	CC
cord-032504-tmohg1mj	223	26	fury	fury	NN
cord-032504-tmohg1mj	223	27	to	to	TO
cord-032504-tmohg1mj	223	28	macrophages	macrophages	VB
cord-032504-tmohg1mj	223	29	The	the	DT
cord-032504-tmohg1mj	223	30	Mtb	Mtb	NNP
cord-032504-tmohg1mj	223	31	-	-	HYPH
cord-032504-tmohg1mj	223	32	HIV	HIV	NNP
cord-032504-tmohg1mj	223	33	syndemic	syndemic	NN
cord-032504-tmohg1mj	223	34	interaction	interaction	NN
cord-032504-tmohg1mj	223	35	:	:	:
cord-032504-tmohg1mj	223	36	why	why	WRB
cord-032504-tmohg1mj	223	37	treating	treat	VBG
cord-032504-tmohg1mj	223	38	M.	M.	NNP
cord-032504-tmohg1mj	223	39	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	223	40	infection	infection	NN
cord-032504-tmohg1mj	223	41	may	may	MD
cord-032504-tmohg1mj	223	42	be	be	VB
cord-032504-tmohg1mj	223	43	crucial	crucial	JJ
cord-032504-tmohg1mj	223	44	for	for	IN
cord-032504-tmohg1mj	223	45	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	223	46	eradication	eradication	NN
cord-032504-tmohg1mj	223	47	Cutting	cutting	NN
cord-032504-tmohg1mj	223	48	edge	edge	NN
cord-032504-tmohg1mj	223	49	:	:	:
cord-032504-tmohg1mj	223	50	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	223	51	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	223	52	induces	induce	VBZ
cord-032504-tmohg1mj	223	53	aerobic	aerobic	JJ
cord-032504-tmohg1mj	223	54	glycolysis	glycolysis	NN
cord-032504-tmohg1mj	223	55	in	in	IN
cord-032504-tmohg1mj	223	56	human	human	JJ
cord-032504-tmohg1mj	223	57	alveolar	alveolar	NN
cord-032504-tmohg1mj	223	58	macrophages	macrophage	NNS
cord-032504-tmohg1mj	223	59	that	that	WDT
cord-032504-tmohg1mj	223	60	is	be	VBZ
cord-032504-tmohg1mj	223	61	required	require	VBN
cord-032504-tmohg1mj	223	62	for	for	IN
cord-032504-tmohg1mj	223	63	control	control	NN
cord-032504-tmohg1mj	223	64	of	of	IN
cord-032504-tmohg1mj	223	65	intracellular	intracellular	JJ
cord-032504-tmohg1mj	223	66	bacillary	bacillary	NN
cord-032504-tmohg1mj	223	67	replication	replication	NN
cord-032504-tmohg1mj	223	68	Growth	growth	NN
cord-032504-tmohg1mj	223	69	of	of	IN
cord-032504-tmohg1mj	223	70	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	223	71	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	223	72	in	in	IN
cord-032504-tmohg1mj	223	73	vivo	vivo	NN
cord-032504-tmohg1mj	223	74	segregates	segregate	VBZ
cord-032504-tmohg1mj	223	75	with	with	IN
cord-032504-tmohg1mj	223	76	host	host	NN
cord-032504-tmohg1mj	223	77	macrophage	macrophage	NN
cord-032504-tmohg1mj	223	78	metabolism	metabolism	NN
cord-032504-tmohg1mj	223	79	and	and	CC
cord-032504-tmohg1mj	223	80	ontogeny	ontogeny	NN
cord-032504-tmohg1mj	224	1	Emerging	emerge	VBG
cord-032504-tmohg1mj	224	2	role	role	NN
cord-032504-tmohg1mj	224	3	and	and	CC
cord-032504-tmohg1mj	224	4	characterization	characterization	NN
cord-032504-tmohg1mj	224	5	of	of	IN
cord-032504-tmohg1mj	224	6	immunometabolism	immunometabolism	NN
cord-032504-tmohg1mj	224	7	:	:	:
cord-032504-tmohg1mj	225	1	relevance	relevance	NN
cord-032504-tmohg1mj	225	2	to	to	IN
cord-032504-tmohg1mj	225	3	HIV	HIV	NNP
cord-032504-tmohg1mj	225	4	pathogenesis	pathogenesis	NN
cord-032504-tmohg1mj	225	5	Intracellular	Intracellular	NNP
cord-032504-tmohg1mj	225	6	expression	expression	NN
cord-032504-tmohg1mj	225	7	of	of	IN
cord-032504-tmohg1mj	225	8	Tat	Tat	NNP
cord-032504-tmohg1mj	225	9	alters	alter	VBZ
cord-032504-tmohg1mj	225	10	mitochondrial	mitochondrial	NN
cord-032504-tmohg1mj	225	11	functions	function	NNS
cord-032504-tmohg1mj	225	12	in	in	IN
cord-032504-tmohg1mj	225	13	T	T	NNP
cord-032504-tmohg1mj	225	14	cells	cell	NNS
cord-032504-tmohg1mj	225	15	:	:	:
cord-032504-tmohg1mj	225	16	a	a	DT
cord-032504-tmohg1mj	225	17	potential	potential	JJ
cord-032504-tmohg1mj	225	18	mechanism	mechanism	NN
cord-032504-tmohg1mj	225	19	to	to	TO
cord-032504-tmohg1mj	225	20	understand	understand	VB
cord-032504-tmohg1mj	225	21	mitochondrial	mitochondrial	JJ
cord-032504-tmohg1mj	225	22	damage	damage	NN
cord-032504-tmohg1mj	225	23	during	during	IN
cord-032504-tmohg1mj	225	24	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	225	25	replication	replication	NN
cord-032504-tmohg1mj	225	26	Abnormal	abnormal	JJ
cord-032504-tmohg1mj	225	27	immunometabolism	immunometabolism	NN
cord-032504-tmohg1mj	225	28	and	and	CC
cord-032504-tmohg1mj	225	29	gene	gene	NN
cord-032504-tmohg1mj	225	30	accessibility	accessibility	NN
cord-032504-tmohg1mj	225	31	in	in	IN
cord-032504-tmohg1mj	225	32	alveolar	alveolar	JJ
cord-032504-tmohg1mj	225	33	macrophages	macrophage	NNS
cord-032504-tmohg1mj	225	34	in	in	IN
cord-032504-tmohg1mj	225	35	HIV	HIV	NNP
cord-032504-tmohg1mj	225	36	HIV	HIV	NNP
cord-032504-tmohg1mj	225	37	infection	infection	NN
cord-032504-tmohg1mj	225	38	and	and	CC
cord-032504-tmohg1mj	225	39	latency	latency	NN
cord-032504-tmohg1mj	225	40	induce	induce	VBP
cord-032504-tmohg1mj	225	41	a	a	DT
cord-032504-tmohg1mj	225	42	unique	unique	JJ
cord-032504-tmohg1mj	225	43	metabolic	metabolic	JJ
cord-032504-tmohg1mj	225	44	signature	signature	NN
cord-032504-tmohg1mj	225	45	in	in	IN
cord-032504-tmohg1mj	225	46	human	human	JJ
cord-032504-tmohg1mj	225	47	macrophages	macrophage	NNS
cord-032504-tmohg1mj	225	48	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	225	49	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	225	50	virulent	virulent	JJ
cord-032504-tmohg1mj	225	51	factor	factor	NN
cord-032504-tmohg1mj	225	52	ESAT-6	esat-6	PRP
cord-032504-tmohg1mj	225	53	drives	drive	VBZ
cord-032504-tmohg1mj	225	54	macrophage	macrophage	NN
cord-032504-tmohg1mj	225	55	differentiation	differentiation	NN
cord-032504-tmohg1mj	225	56	toward	toward	IN
cord-032504-tmohg1mj	225	57	the	the	DT
cord-032504-tmohg1mj	225	58	pro	pro	JJ
cord-032504-tmohg1mj	225	59	-	-	JJ
cord-032504-tmohg1mj	225	60	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	225	61	M1	M1	NNP
cord-032504-tmohg1mj	225	62	phenotype	phenotype	NN
cord-032504-tmohg1mj	225	63	and	and	CC
cord-032504-tmohg1mj	225	64	subsequently	subsequently	RB
cord-032504-tmohg1mj	225	65	switches	switch	VBZ
cord-032504-tmohg1mj	225	66	it	-PRON-	PRP
cord-032504-tmohg1mj	225	67	to	to	IN
cord-032504-tmohg1mj	225	68	the	the	DT
cord-032504-tmohg1mj	225	69	anti	anti	JJ
cord-032504-tmohg1mj	225	70	-	-	JJ
cord-032504-tmohg1mj	225	71	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	225	72	M2	M2	NNP
cord-032504-tmohg1mj	225	73	phenotype	phenotype	NN
cord-032504-tmohg1mj	225	74	Depressed	depressed	JJ
cord-032504-tmohg1mj	225	75	T	t	NN
cord-032504-tmohg1mj	225	76	-	-	HYPH
cord-032504-tmohg1mj	225	77	cell	cell	NN
cord-032504-tmohg1mj	225	78	interferon	interferon	NN
cord-032504-tmohg1mj	225	79	-	-	HYPH
cord-032504-tmohg1mj	225	80	gamma	gamma	NN
cord-032504-tmohg1mj	225	81	responses	response	NNS
cord-032504-tmohg1mj	225	82	in	in	IN
cord-032504-tmohg1mj	225	83	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	225	84	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	225	85	:	:	:
cord-032504-tmohg1mj	225	86	analysis	analysis	NN
cord-032504-tmohg1mj	225	87	of	of	IN
cord-032504-tmohg1mj	225	88	underlying	underlie	VBG
cord-032504-tmohg1mj	225	89	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	225	90	and	and	CC
cord-032504-tmohg1mj	225	91	modulation	modulation	NN
cord-032504-tmohg1mj	225	92	with	with	IN
cord-032504-tmohg1mj	225	93	therapy	therapy	NN
cord-032504-tmohg1mj	226	1	The	the	DT
cord-032504-tmohg1mj	226	2	significance	significance	NN
cord-032504-tmohg1mj	226	3	of	of	IN
cord-032504-tmohg1mj	226	4	interferon	interferon	NN
cord-032504-tmohg1mj	226	5	-	-	HYPH
cord-032504-tmohg1mj	226	6	γ	γ	NN
cord-032504-tmohg1mj	226	7	in	in	IN
cord-032504-tmohg1mj	226	8	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	226	9	pathogenesis	pathogenesis	NN
cord-032504-tmohg1mj	226	10	,	,	,
cord-032504-tmohg1mj	226	11	therapy	therapy	NN
cord-032504-tmohg1mj	226	12	,	,	,
cord-032504-tmohg1mj	226	13	and	and	CC
cord-032504-tmohg1mj	226	14	prophylaxis	prophylaxis	NN
cord-032504-tmohg1mj	226	15	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	226	16	gp120	gp120	NNP
cord-032504-tmohg1mj	226	17	Induces	induce	VBZ
cord-032504-tmohg1mj	226	18	IL-4	IL-4	NNP
cord-032504-tmohg1mj	226	19	and	and	CC
cord-032504-tmohg1mj	226	20	IL-13	IL-13	NNP
cord-032504-tmohg1mj	226	21	release	release	NN
cord-032504-tmohg1mj	226	22	from	from	IN
cord-032504-tmohg1mj	226	23	human	human	JJ
cord-032504-tmohg1mj	226	24	FcεRI	FcεRI	NNP
cord-032504-tmohg1mj	226	25	+	+	CC
cord-032504-tmohg1mj	227	1	cells	cell	NNS
cord-032504-tmohg1mj	227	2	through	through	IN
cord-032504-tmohg1mj	227	3	interaction	interaction	NN
cord-032504-tmohg1mj	227	4	with	with	IN
cord-032504-tmohg1mj	227	5	the	the	DT
cord-032504-tmohg1mj	227	6	V	v	NN
cord-032504-tmohg1mj	227	7	H	h	NN
cord-032504-tmohg1mj	227	8	3	3	CD
cord-032504-tmohg1mj	227	9	region	region	NN
cord-032504-tmohg1mj	227	10	of	of	IN
cord-032504-tmohg1mj	227	11	IgE	IgE	NNP
cord-032504-tmohg1mj	227	12	Endogenously	Endogenously	NNP
cord-032504-tmohg1mj	227	13	activated	activate	VBD
cord-032504-tmohg1mj	227	14	interleukin-4	interleukin-4	NNP
cord-032504-tmohg1mj	227	15	differentiates	differentiate	VBZ
cord-032504-tmohg1mj	227	16	disease	disease	NN
cord-032504-tmohg1mj	227	17	progressors	progressor	NNS
cord-032504-tmohg1mj	227	18	and	and	CC
cord-032504-tmohg1mj	227	19	non	non	NNS
cord-032504-tmohg1mj	227	20	-	-	NNS
cord-032504-tmohg1mj	227	21	progressors	progressor	NNS
cord-032504-tmohg1mj	227	22	in	in	IN
cord-032504-tmohg1mj	227	23	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	227	24	susceptible	susceptible	JJ
cord-032504-tmohg1mj	227	25	families	family	NNS
cord-032504-tmohg1mj	227	26	:	:	:
cord-032504-tmohg1mj	228	1	a	a	DT
cord-032504-tmohg1mj	228	2	2-year	2-year	CD
cord-032504-tmohg1mj	228	3	biomarkers	biomarker	NNS
cord-032504-tmohg1mj	228	4	follow	follow	VB
cord-032504-tmohg1mj	228	5	-	-	HYPH
cord-032504-tmohg1mj	228	6	up	up	NN
cord-032504-tmohg1mj	228	7	study	study	NN
cord-032504-tmohg1mj	228	8	Increased	increase	VBN
cord-032504-tmohg1mj	228	9	Interleukin-4	Interleukin-4	NNP
cord-032504-tmohg1mj	228	10	production	production	NN
cord-032504-tmohg1mj	228	11	by	by	IN
cord-032504-tmohg1mj	228	12	CD8	CD8	NNP
cord-032504-tmohg1mj	228	13	and	and	CC
cord-032504-tmohg1mj	228	14	gammadelta	gammadelta	NNP
cord-032504-tmohg1mj	228	15	T	T	NNP
cord-032504-tmohg1mj	228	16	cells	cell	NNS
cord-032504-tmohg1mj	228	17	in	in	IN
cord-032504-tmohg1mj	228	18	health	health	NN
cord-032504-tmohg1mj	228	19	-	-	HYPH
cord-032504-tmohg1mj	228	20	care	care	NN
cord-032504-tmohg1mj	228	21	workers	worker	NNS
cord-032504-tmohg1mj	228	22	is	be	VBZ
cord-032504-tmohg1mj	228	23	associated	associate	VBN
cord-032504-tmohg1mj	228	24	with	with	IN
cord-032504-tmohg1mj	228	25	the	the	DT
cord-032504-tmohg1mj	228	26	subsequent	subsequent	JJ
cord-032504-tmohg1mj	228	27	development	development	NN
cord-032504-tmohg1mj	228	28	of	of	IN
cord-032504-tmohg1mj	228	29	active	active	JJ
cord-032504-tmohg1mj	228	30	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	228	31	Increased	increase	VBN
cord-032504-tmohg1mj	228	32	production	production	NN
cord-032504-tmohg1mj	228	33	of	of	IN
cord-032504-tmohg1mj	228	34	interleukin	interleukin	NN
cord-032504-tmohg1mj	228	35	4	4	CD
cord-032504-tmohg1mj	228	36	by	by	IN
cord-032504-tmohg1mj	228	37	CD4	CD4	NNP
cord-032504-tmohg1mj	228	38	+	+	CC
cord-032504-tmohg1mj	228	39	and	and	CC
cord-032504-tmohg1mj	228	40	CD8	CD8	NNP
cord-032504-tmohg1mj	228	41	+	+	CC
cord-032504-tmohg1mj	228	42	T	T	NNP
cord-032504-tmohg1mj	228	43	cells	cell	NNS
cord-032504-tmohg1mj	228	44	from	from	IN
cord-032504-tmohg1mj	228	45	patients	patient	NNS
cord-032504-tmohg1mj	228	46	with	with	IN
cord-032504-tmohg1mj	228	47	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	228	48	is	be	VBZ
cord-032504-tmohg1mj	228	49	related	relate	VBN
cord-032504-tmohg1mj	228	50	to	to	IN
cord-032504-tmohg1mj	228	51	the	the	DT
cord-032504-tmohg1mj	228	52	presence	presence	NN
cord-032504-tmohg1mj	228	53	of	of	IN
cord-032504-tmohg1mj	228	54	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	228	55	cavities	cavity	NNS
cord-032504-tmohg1mj	228	56	Role	role	NN
cord-032504-tmohg1mj	228	57	of	of	IN
cord-032504-tmohg1mj	228	58	granulocyte	granulocyte	NN
cord-032504-tmohg1mj	228	59	-	-	HYPH
cord-032504-tmohg1mj	228	60	macrophage	macrophage	NN
cord-032504-tmohg1mj	228	61	colony	colony	NN
cord-032504-tmohg1mj	228	62	-	-	HYPH
cord-032504-tmohg1mj	228	63	stimulating	stimulate	VBG
cord-032504-tmohg1mj	228	64	factor	factor	NN
cord-032504-tmohg1mj	228	65	production	production	NN
cord-032504-tmohg1mj	228	66	by	by	IN
cord-032504-tmohg1mj	228	67	T	t	NN
cord-032504-tmohg1mj	228	68	cells	cell	NNS
cord-032504-tmohg1mj	228	69	during	during	IN
cord-032504-tmohg1mj	228	70	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	228	71	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	228	72	infection	infection	NN
cord-032504-tmohg1mj	229	1	Understanding	understand	VBG
cord-032504-tmohg1mj	229	2	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	229	3	-	-	HYPH
cord-032504-tmohg1mj	229	4	analyzing	analyze	VBG
cord-032504-tmohg1mj	229	5	the	the	DT
cord-032504-tmohg1mj	229	6	origin	origin	NN
cord-032504-tmohg1mj	229	7	of	of	IN
cord-032504-tmohg1mj	229	8	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	229	9	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	229	10	pathogenicity	pathogenicity	NN
cord-032504-tmohg1mj	229	11	Human	human	JJ
cord-032504-tmohg1mj	229	12	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	229	13	virus	virus	NN
cord-032504-tmohg1mj	229	14	type	type	NN
cord-032504-tmohg1mj	229	15	1	1	CD
cord-032504-tmohg1mj	229	16	infection	infection	NN
cord-032504-tmohg1mj	229	17	inhibits	inhibit	VBZ
cord-032504-tmohg1mj	229	18	granulocyte	granulocyte	NN
cord-032504-tmohg1mj	229	19	-	-	HYPH
cord-032504-tmohg1mj	229	20	macrophage	macrophage	NN
cord-032504-tmohg1mj	229	21	colony	colony	NN
cord-032504-tmohg1mj	229	22	-	-	HYPH
cord-032504-tmohg1mj	229	23	stimulating	stimulate	VBG
cord-032504-tmohg1mj	229	24	factor	factor	NN
cord-032504-tmohg1mj	229	25	-	-	HYPH
cord-032504-tmohg1mj	229	26	induced	induce	VBN
cord-032504-tmohg1mj	229	27	activation	activation	NN
cord-032504-tmohg1mj	229	28	of	of	IN
cord-032504-tmohg1mj	229	29	STAT5A	STAT5A	NNP
cord-032504-tmohg1mj	229	30	in	in	IN
cord-032504-tmohg1mj	229	31	human	human	JJ
cord-032504-tmohg1mj	229	32	monocyte	monocyte	NN
cord-032504-tmohg1mj	229	33	-	-	HYPH
cord-032504-tmohg1mj	229	34	derived	derive	VBN
cord-032504-tmohg1mj	229	35	macrophages	macrophage	NNS
cord-032504-tmohg1mj	229	36	Relative	relative	JJ
cord-032504-tmohg1mj	229	37	levels	level	NNS
cord-032504-tmohg1mj	229	38	of	of	IN
cord-032504-tmohg1mj	230	1	M	M	NNP
cord-032504-tmohg1mj	230	2	-	-	HYPH
cord-032504-tmohg1mj	230	3	CSF	CSF	NNP
cord-032504-tmohg1mj	230	4	and	and	CC
cord-032504-tmohg1mj	230	5	GM	GM	NNP
cord-032504-tmohg1mj	230	6	-	-	HYPH
cord-032504-tmohg1mj	230	7	CSF	CSF	NNP
cord-032504-tmohg1mj	230	8	influence	influence	VB
cord-032504-tmohg1mj	230	9	the	the	DT
cord-032504-tmohg1mj	230	10	specific	specific	JJ
cord-032504-tmohg1mj	230	11	generation	generation	NN
cord-032504-tmohg1mj	230	12	of	of	IN
cord-032504-tmohg1mj	230	13	macrophage	macrophage	NN
cord-032504-tmohg1mj	230	14	populations	population	NNS
cord-032504-tmohg1mj	230	15	during	during	IN
cord-032504-tmohg1mj	230	16	infection	infection	NN
cord-032504-tmohg1mj	230	17	with	with	IN
cord-032504-tmohg1mj	230	18	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	230	19	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	230	20	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	230	21	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	230	22	replicates	replicate	VBZ
cord-032504-tmohg1mj	230	23	within	within	IN
cord-032504-tmohg1mj	230	24	necrotic	necrotic	JJ
cord-032504-tmohg1mj	230	25	human	human	JJ
cord-032504-tmohg1mj	230	26	macrophages	macrophage	NNS
cord-032504-tmohg1mj	231	1	IRAK	IRAK	NNP
cord-032504-tmohg1mj	231	2	-	-	HYPH
cord-032504-tmohg1mj	231	3	M	M	NNP
cord-032504-tmohg1mj	231	4	alters	alter	VBZ
cord-032504-tmohg1mj	231	5	the	the	DT
cord-032504-tmohg1mj	231	6	polarity	polarity	NN
cord-032504-tmohg1mj	231	7	of	of	IN
cord-032504-tmohg1mj	231	8	macrophages	macrophage	NNS
cord-032504-tmohg1mj	231	9	to	to	TO
cord-032504-tmohg1mj	231	10	facilitate	facilitate	VB
cord-032504-tmohg1mj	231	11	the	the	DT
cord-032504-tmohg1mj	231	12	survival	survival	NN
cord-032504-tmohg1mj	231	13	of	of	IN
cord-032504-tmohg1mj	231	14	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	231	15	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	231	16	Glutathione	glutathione	NN
cord-032504-tmohg1mj	231	17	and	and	CC
cord-032504-tmohg1mj	231	18	infection	infection	NN
cord-032504-tmohg1mj	231	19	Mechanisms	Mechanisms	NNPS
cord-032504-tmohg1mj	231	20	of	of	IN
cord-032504-tmohg1mj	231	21	control	control	NN
cord-032504-tmohg1mj	231	22	of	of	IN
cord-032504-tmohg1mj	231	23	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	231	24	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	231	25	by	by	IN
cord-032504-tmohg1mj	231	26	NK	NK	NNP
cord-032504-tmohg1mj	231	27	cells	cell	NNS
cord-032504-tmohg1mj	231	28	:	:	:
cord-032504-tmohg1mj	231	29	role	role	NN
cord-032504-tmohg1mj	231	30	of	of	IN
cord-032504-tmohg1mj	231	31	glutathione	glutathione	NN
cord-032504-tmohg1mj	231	32	Glutathione	glutathione	NN
cord-032504-tmohg1mj	231	33	levels	level	NNS
cord-032504-tmohg1mj	231	34	in	in	IN
cord-032504-tmohg1mj	231	35	antigen	antigen	NN
cord-032504-tmohg1mj	231	36	-	-	HYPH
cord-032504-tmohg1mj	231	37	presenting	present	VBG
cord-032504-tmohg1mj	231	38	cells	cell	NNS
cord-032504-tmohg1mj	231	39	modulate	modulate	VBP
cord-032504-tmohg1mj	231	40	Th1	th1	NN
cord-032504-tmohg1mj	231	41	versus	versus	IN
cord-032504-tmohg1mj	231	42	Th2	th2	CD
cord-032504-tmohg1mj	231	43	response	response	NN
cord-032504-tmohg1mj	231	44	patterns	pattern	NNS
cord-032504-tmohg1mj	232	1	Oxidative	oxidative	JJ
cord-032504-tmohg1mj	232	2	stress	stress	NN
cord-032504-tmohg1mj	232	3	during	during	IN
cord-032504-tmohg1mj	232	4	HIV	HIV	NNP
cord-032504-tmohg1mj	232	5	infection	infection	NN
cord-032504-tmohg1mj	232	6	:	:	:
cord-032504-tmohg1mj	233	1	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	233	2	and	and	CC
cord-032504-tmohg1mj	233	3	consequences	consequence	NNS
cord-032504-tmohg1mj	233	4	Anti	anti	JJ
cord-032504-tmohg1mj	233	5	-	-	JJ
cord-032504-tmohg1mj	233	6	retroviral	retroviral	JJ
cord-032504-tmohg1mj	233	7	therapy	therapy	NN
cord-032504-tmohg1mj	233	8	is	be	VBZ
cord-032504-tmohg1mj	233	9	associated	associate	VBN
cord-032504-tmohg1mj	233	10	with	with	IN
cord-032504-tmohg1mj	233	11	decreased	decrease	VBN
cord-032504-tmohg1mj	233	12	alveolar	alveolar	JJ
cord-032504-tmohg1mj	233	13	glutathione	glutathione	NN
cord-032504-tmohg1mj	233	14	levels	level	NNS
cord-032504-tmohg1mj	233	15	even	even	RB
cord-032504-tmohg1mj	233	16	in	in	IN
cord-032504-tmohg1mj	233	17	healthy	healthy	JJ
cord-032504-tmohg1mj	233	18	HIV	HIV	NNP
cord-032504-tmohg1mj	233	19	-	-	HYPH
cord-032504-tmohg1mj	233	20	infected	infect	VBN
cord-032504-tmohg1mj	233	21	individuals	individual	NNS
cord-032504-tmohg1mj	234	1	Glutathione	glutathione	NN
cord-032504-tmohg1mj	234	2	supplementation	supplementation	NN
cord-032504-tmohg1mj	234	3	improves	improve	VBZ
cord-032504-tmohg1mj	234	4	macrophage	macrophage	NN
cord-032504-tmohg1mj	234	5	functions	function	NNS
cord-032504-tmohg1mj	234	6	in	in	IN
cord-032504-tmohg1mj	235	1	HIV	HIV	NNP
cord-032504-tmohg1mj	235	2	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	235	3	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	235	4	WhiB3	WhiB3	NNP
cord-032504-tmohg1mj	235	5	maintains	maintain	VBZ
cord-032504-tmohg1mj	235	6	redox	redox	JJ
cord-032504-tmohg1mj	235	7	homeostasis	homeostasis	NN
cord-032504-tmohg1mj	235	8	by	by	IN
cord-032504-tmohg1mj	235	9	regulating	regulate	VBG
cord-032504-tmohg1mj	235	10	virulence	virulence	NN
cord-032504-tmohg1mj	235	11	lipid	lipid	NN
cord-032504-tmohg1mj	235	12	anabolism	anabolism	NN
cord-032504-tmohg1mj	235	13	to	to	TO
cord-032504-tmohg1mj	235	14	modulate	modulate	VB
cord-032504-tmohg1mj	235	15	macrophage	macrophage	NN
cord-032504-tmohg1mj	235	16	response	response	NN
cord-032504-tmohg1mj	235	17	Redox	Redox	NNP
cord-032504-tmohg1mj	235	18	biology	biology	NN
cord-032504-tmohg1mj	235	19	of	of	IN
cord-032504-tmohg1mj	236	1	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	236	2	pathogenesis	pathogenesis	VBP
cord-032504-tmohg1mj	236	3	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	236	4	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	236	5	induction	induction	NN
cord-032504-tmohg1mj	236	6	of	of	IN
cord-032504-tmohg1mj	236	7	heme	heme	NN
cord-032504-tmohg1mj	236	8	oxygenase-1	oxygenase-1	NNP
cord-032504-tmohg1mj	236	9	expression	expression	NN
cord-032504-tmohg1mj	236	10	is	be	VBZ
cord-032504-tmohg1mj	236	11	dependent	dependent	JJ
cord-032504-tmohg1mj	236	12	on	on	IN
cord-032504-tmohg1mj	236	13	oxidative	oxidative	JJ
cord-032504-tmohg1mj	236	14	stress	stress	NN
cord-032504-tmohg1mj	236	15	and	and	CC
cord-032504-tmohg1mj	236	16	reflects	reflect	VBZ
cord-032504-tmohg1mj	236	17	treatment	treatment	NN
cord-032504-tmohg1mj	236	18	outcomes	outcome	NNS
cord-032504-tmohg1mj	236	19	Glutathione	glutathione	NN
cord-032504-tmohg1mj	236	20	-	-	HYPH
cord-032504-tmohg1mj	236	21	redox	redox	NN
cord-032504-tmohg1mj	236	22	balance	balance	NN
cord-032504-tmohg1mj	236	23	regulates	regulate	VBZ
cord-032504-tmohg1mj	236	24	c	c	NNP
cord-032504-tmohg1mj	236	25	-	-	HYPH
cord-032504-tmohg1mj	236	26	rel	rel	NN
cord-032504-tmohg1mj	236	27	-	-	HYPH
cord-032504-tmohg1mj	236	28	driven	drive	VBN
cord-032504-tmohg1mj	236	29	IL-12	IL-12	NNP
cord-032504-tmohg1mj	236	30	production	production	NN
cord-032504-tmohg1mj	236	31	in	in	IN
cord-032504-tmohg1mj	236	32	macrophages	macrophage	NNS
cord-032504-tmohg1mj	236	33	:	:	:
cord-032504-tmohg1mj	236	34	possible	possible	JJ
cord-032504-tmohg1mj	236	35	implications	implication	NNS
cord-032504-tmohg1mj	236	36	in	in	IN
cord-032504-tmohg1mj	236	37	antituberculosis	antituberculosis	NN
cord-032504-tmohg1mj	236	38	immunotherapy	immunotherapy	NN
cord-032504-tmohg1mj	236	39	Evidence	evidence	NN
cord-032504-tmohg1mj	236	40	for	for	IN
cord-032504-tmohg1mj	236	41	oxidative	oxidative	JJ
cord-032504-tmohg1mj	236	42	stress	stress	NN
cord-032504-tmohg1mj	236	43	and	and	CC
cord-032504-tmohg1mj	236	44	defective	defective	JJ
cord-032504-tmohg1mj	236	45	antioxidant	antioxidant	JJ
cord-032504-tmohg1mj	236	46	response	response	NN
cord-032504-tmohg1mj	236	47	in	in	IN
cord-032504-tmohg1mj	236	48	guinea	guinea	NN
cord-032504-tmohg1mj	236	49	pigs	pig	NNS
cord-032504-tmohg1mj	236	50	with	with	IN
cord-032504-tmohg1mj	236	51	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	236	52	Glutathione	glutathione	NN
cord-032504-tmohg1mj	236	53	levels	level	NNS
cord-032504-tmohg1mj	236	54	and	and	CC
cord-032504-tmohg1mj	236	55	immune	immune	JJ
cord-032504-tmohg1mj	236	56	responses	response	NNS
cord-032504-tmohg1mj	236	57	in	in	IN
cord-032504-tmohg1mj	236	58	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	236	59	patients	patient	NNS
cord-032504-tmohg1mj	236	60	Liposomal	Liposomal	NNP
cord-032504-tmohg1mj	236	61	glutathione	glutathione	NN
cord-032504-tmohg1mj	236	62	supplementation	supplementation	NN
cord-032504-tmohg1mj	237	1	restores	restore	VBZ
cord-032504-tmohg1mj	237	2	TH1	TH1	NNP
cord-032504-tmohg1mj	237	3	cytokine	cytokine	NN
cord-032504-tmohg1mj	237	4	response	response	NN
cord-032504-tmohg1mj	237	5	to	to	IN
cord-032504-tmohg1mj	237	6	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	237	7	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	237	8	infection	infection	NN
cord-032504-tmohg1mj	237	9	in	in	IN
cord-032504-tmohg1mj	237	10	HIV	HIV	NNP
cord-032504-tmohg1mj	237	11	-	-	HYPH
cord-032504-tmohg1mj	237	12	infected	infect	VBN
cord-032504-tmohg1mj	237	13	individuals	individual	NNS
cord-032504-tmohg1mj	237	14	Glutathione	glutathione	NN
cord-032504-tmohg1mj	237	15	and	and	CC
cord-032504-tmohg1mj	237	16	adaptive	adaptive	JJ
cord-032504-tmohg1mj	237	17	immune	immune	JJ
cord-032504-tmohg1mj	237	18	responses	response	NNS
cord-032504-tmohg1mj	237	19	against	against	IN
cord-032504-tmohg1mj	237	20	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	237	21	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	237	22	infection	infection	NN
cord-032504-tmohg1mj	237	23	in	in	IN
cord-032504-tmohg1mj	237	24	healthy	healthy	JJ
cord-032504-tmohg1mj	237	25	and	and	CC
cord-032504-tmohg1mj	237	26	HIV	HIV	NNP
cord-032504-tmohg1mj	237	27	infected	infect	VBD
cord-032504-tmohg1mj	237	28	individuals	individual	NNS
cord-032504-tmohg1mj	237	29	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	237	30	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	237	31	reactivates	reactivate	VBZ
cord-032504-tmohg1mj	237	32	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	237	33	via	via	IN
cord-032504-tmohg1mj	237	34	exosome	exosome	RB
cord-032504-tmohg1mj	237	35	-	-	HYPH
cord-032504-tmohg1mj	237	36	mediated	mediate	VBN
cord-032504-tmohg1mj	237	37	resetting	resetting	NN
cord-032504-tmohg1mj	237	38	of	of	IN
cord-032504-tmohg1mj	237	39	cellular	cellular	JJ
cord-032504-tmohg1mj	237	40	redox	redox	NN
cord-032504-tmohg1mj	237	41	potential	potential	NN
cord-032504-tmohg1mj	237	42	and	and	CC
cord-032504-tmohg1mj	237	43	bioenergetics	bioenergetic	NNS
cord-032504-tmohg1mj	237	44	.	.	.
cord-032504-tmohg1mj	238	1	mBio	mBio	NNP
cord-032504-tmohg1mj	239	1	The	the	DT
cord-032504-tmohg1mj	239	2	delivery	delivery	NN
cord-032504-tmohg1mj	239	3	of	of	IN
cord-032504-tmohg1mj	239	4	endocytosed	endocytosed	JJ
cord-032504-tmohg1mj	239	5	cargo	cargo	NN
cord-032504-tmohg1mj	239	6	to	to	IN
cord-032504-tmohg1mj	239	7	lysosomes	lysosomes	VB
cord-032504-tmohg1mj	239	8	Endosome	Endosome	NNP
cord-032504-tmohg1mj	239	9	-	-	HYPH
cord-032504-tmohg1mj	239	10	lysosome	lysosome	NN
cord-032504-tmohg1mj	239	11	fusion	fusion	NN
cord-032504-tmohg1mj	239	12	Insights	insight	NNS
cord-032504-tmohg1mj	239	13	into	into	IN
cord-032504-tmohg1mj	239	14	macrophage	macrophage	NN
cord-032504-tmohg1mj	239	15	autophagy	autophagy	NN
cord-032504-tmohg1mj	239	16	in	in	IN
cord-032504-tmohg1mj	239	17	latent	latent	JJ
cord-032504-tmohg1mj	239	18	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	239	19	infection	infection	NN
cord-032504-tmohg1mj	239	20	:	:	:
cord-032504-tmohg1mj	239	21	role	role	NN
cord-032504-tmohg1mj	239	22	of	of	IN
cord-032504-tmohg1mj	239	23	heat	heat	NN
cord-032504-tmohg1mj	239	24	shock	shock	NN
cord-032504-tmohg1mj	239	25	protein	protein	NN
cord-032504-tmohg1mj	239	26	16.3	16.3	CD
cord-032504-tmohg1mj	239	27	Reduced	reduce	VBN
cord-032504-tmohg1mj	239	28	binding	binding	NN
cord-032504-tmohg1mj	239	29	and	and	CC
cord-032504-tmohg1mj	239	30	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	239	31	of	of	IN
cord-032504-tmohg1mj	239	32	Pneumocystis	Pneumocystis	NNP
cord-032504-tmohg1mj	239	33	carinii	carinii	NN
cord-032504-tmohg1mj	239	34	by	by	IN
cord-032504-tmohg1mj	239	35	alveolar	alveolar	JJ
cord-032504-tmohg1mj	239	36	macrophages	macrophage	NNS
cord-032504-tmohg1mj	239	37	from	from	IN
cord-032504-tmohg1mj	239	38	persons	person	NNS
cord-032504-tmohg1mj	239	39	infected	infect	VBN
cord-032504-tmohg1mj	239	40	with	with	IN
cord-032504-tmohg1mj	239	41	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	239	42	correlates	correlate	VBZ
cord-032504-tmohg1mj	239	43	with	with	IN
cord-032504-tmohg1mj	239	44	mannose	mannose	JJ
cord-032504-tmohg1mj	239	45	receptor	receptor	NN
cord-032504-tmohg1mj	239	46	downregulation	downregulation	NN
cord-032504-tmohg1mj	239	47	Toll	Toll	NNP
cord-032504-tmohg1mj	239	48	-	-	HYPH
cord-032504-tmohg1mj	239	49	like	like	JJ
cord-032504-tmohg1mj	239	50	receptor	receptor	NN
cord-032504-tmohg1mj	239	51	2-dependent	2-dependent	CD
cord-032504-tmohg1mj	239	52	extracellular	extracellular	JJ
cord-032504-tmohg1mj	239	53	signalregulated	signalregulate	VBN
cord-032504-tmohg1mj	239	54	kinase	kinase	NN
cord-032504-tmohg1mj	239	55	signaling	signal	VBG
cord-032504-tmohg1mj	239	56	in	in	IN
cord-032504-tmohg1mj	239	57	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	239	58	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	239	59	-	-	HYPH
cord-032504-tmohg1mj	239	60	infected	infect	VBN
cord-032504-tmohg1mj	239	61	macrophages	macrophage	NNS
cord-032504-tmohg1mj	239	62	drives	drive	VBZ
cord-032504-tmohg1mj	239	63	anti	anti	JJ
cord-032504-tmohg1mj	239	64	-	-	JJ
cord-032504-tmohg1mj	239	65	inflammatory	inflammatory	JJ
cord-032504-tmohg1mj	239	66	responses	response	NNS
cord-032504-tmohg1mj	239	67	and	and	CC
cord-032504-tmohg1mj	239	68	inhibits	inhibit	VBZ
cord-032504-tmohg1mj	239	69	Th1	th1	NN
cord-032504-tmohg1mj	239	70	polarization	polarization	NN
cord-032504-tmohg1mj	239	71	of	of	IN
cord-032504-tmohg1mj	239	72	responding	respond	VBG
cord-032504-tmohg1mj	239	73	T	T	NNP
cord-032504-tmohg1mj	239	74	cells	cell	NNS
cord-032504-tmohg1mj	239	75	Toll	toll	NN
cord-032504-tmohg1mj	239	76	-	-	HYPH
cord-032504-tmohg1mj	239	77	like	like	JJ
cord-032504-tmohg1mj	239	78	receptor	receptor	NN
cord-032504-tmohg1mj	239	79	-	-	HYPH
cord-032504-tmohg1mj	239	80	induced	induce	VBN
cord-032504-tmohg1mj	239	81	arginase	arginase	NN
cord-032504-tmohg1mj	239	82	1	1	CD
cord-032504-tmohg1mj	239	83	in	in	IN
cord-032504-tmohg1mj	239	84	macrophages	macrophage	NNS
cord-032504-tmohg1mj	239	85	thwarts	thwart	VBZ
cord-032504-tmohg1mj	239	86	effective	effective	JJ
cord-032504-tmohg1mj	239	87	immunity	immunity	NN
cord-032504-tmohg1mj	239	88	against	against	IN
cord-032504-tmohg1mj	239	89	intracellular	intracellular	JJ
cord-032504-tmohg1mj	239	90	pathogens	pathogen	NNS
cord-032504-tmohg1mj	239	91	Human	human	JJ
cord-032504-tmohg1mj	239	92	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	239	93	virus	virus	NN
cord-032504-tmohg1mj	239	94	infection	infection	NN
cord-032504-tmohg1mj	239	95	alters	alter	VBZ
cord-032504-tmohg1mj	239	96	tumor	tumor	NN
cord-032504-tmohg1mj	239	97	necrosis	necrosis	NN
cord-032504-tmohg1mj	239	98	factor	factor	NN
cord-032504-tmohg1mj	239	99	alpha	alpha	NN
cord-032504-tmohg1mj	239	100	production	production	NN
cord-032504-tmohg1mj	239	101	via	via	IN
cord-032504-tmohg1mj	239	102	Toll	toll	NN
cord-032504-tmohg1mj	239	103	-	-	HYPH
cord-032504-tmohg1mj	239	104	like	like	JJ
cord-032504-tmohg1mj	239	105	receptor	receptor	NN
cord-032504-tmohg1mj	239	106	-	-	HYPH
cord-032504-tmohg1mj	239	107	dependent	dependent	JJ
cord-032504-tmohg1mj	239	108	pathways	pathway	NNS
cord-032504-tmohg1mj	239	109	in	in	IN
cord-032504-tmohg1mj	239	110	alveolar	alveolar	JJ
cord-032504-tmohg1mj	239	111	macrophages	macrophage	NNS
cord-032504-tmohg1mj	239	112	and	and	CC
cord-032504-tmohg1mj	239	113	U1	u1	NN
cord-032504-tmohg1mj	239	114	cells	cell	NNS
cord-032504-tmohg1mj	240	1	The	the	DT
cord-032504-tmohg1mj	240	2	alveolar	alveolar	JJ
cord-032504-tmohg1mj	240	3	microenvironment	microenvironment	NN
cord-032504-tmohg1mj	240	4	of	of	IN
cord-032504-tmohg1mj	240	5	patients	patient	NNS
cord-032504-tmohg1mj	240	6	infected	infect	VBN
cord-032504-tmohg1mj	240	7	with	with	IN
cord-032504-tmohg1mj	240	8	human	human	JJ
cord-032504-tmohg1mj	240	9	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	240	10	virus	virus	NN
cord-032504-tmohg1mj	240	11	does	do	VBZ
cord-032504-tmohg1mj	240	12	not	not	RB
cord-032504-tmohg1mj	240	13	modify	modify	VB
cord-032504-tmohg1mj	240	14	alveolar	alveolar	JJ
cord-032504-tmohg1mj	240	15	macrophage	macrophage	NN
cord-032504-tmohg1mj	240	16	interactions	interaction	NNS
cord-032504-tmohg1mj	240	17	with	with	IN
cord-032504-tmohg1mj	240	18	Streptococcus	Streptococcus	NNP
cord-032504-tmohg1mj	240	19	pneumoniae	pneumoniae	NN
cord-032504-tmohg1mj	240	20	Inhibition	inhibition	NN
cord-032504-tmohg1mj	240	21	of	of	IN
cord-032504-tmohg1mj	240	22	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	240	23	in	in	IN
cord-032504-tmohg1mj	240	24	HIV-1-infected	hiv-1-infecte	VBN
cord-032504-tmohg1mj	240	25	macrophages	macrophage	NNS
cord-032504-tmohg1mj	240	26	relies	rely	VBZ
cord-032504-tmohg1mj	240	27	on	on	IN
cord-032504-tmohg1mj	240	28	Nef	Nef	NNP
cord-032504-tmohg1mj	240	29	-	-	HYPH
cord-032504-tmohg1mj	240	30	dependent	dependent	JJ
cord-032504-tmohg1mj	240	31	alteration	alteration	NN
cord-032504-tmohg1mj	240	32	of	of	IN
cord-032504-tmohg1mj	240	33	focal	focal	JJ
cord-032504-tmohg1mj	240	34	delivery	delivery	NN
cord-032504-tmohg1mj	240	35	of	of	IN
cord-032504-tmohg1mj	240	36	recycling	recycling	NN
cord-032504-tmohg1mj	240	37	compartments	compartment	NNS
cord-032504-tmohg1mj	240	38	Small	small	JJ
cord-032504-tmohg1mj	240	39	alveolar	alveolar	JJ
cord-032504-tmohg1mj	240	40	macrophages	macrophage	NNS
cord-032504-tmohg1mj	240	41	are	be	VBP
cord-032504-tmohg1mj	240	42	infected	infect	VBN
cord-032504-tmohg1mj	240	43	preferentially	preferentially	RB
cord-032504-tmohg1mj	240	44	by	by	IN
cord-032504-tmohg1mj	240	45	HIV	HIV	NNP
cord-032504-tmohg1mj	240	46	and	and	CC
cord-032504-tmohg1mj	240	47	exhibit	exhibit	VB
cord-032504-tmohg1mj	240	48	impaired	impaired	JJ
cord-032504-tmohg1mj	240	49	phagocytic	phagocytic	JJ
cord-032504-tmohg1mj	240	50	function	function	NN
cord-032504-tmohg1mj	241	1	Defective	defective	JJ
cord-032504-tmohg1mj	241	2	phagocytosis	phagocytosis	NN
cord-032504-tmohg1mj	241	3	by	by	IN
cord-032504-tmohg1mj	241	4	human	human	JJ
cord-032504-tmohg1mj	241	5	monocyte	monocyte	NNP
cord-032504-tmohg1mj	241	6	/	/	SYM
cord-032504-tmohg1mj	241	7	macrophages	macrophage	NNS
cord-032504-tmohg1mj	241	8	following	follow	VBG
cord-032504-tmohg1mj	241	9	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	241	10	infection	infection	NN
cord-032504-tmohg1mj	241	11	:	:	:
cord-032504-tmohg1mj	241	12	underlying	underlie	VBG
cord-032504-tmohg1mj	241	13	mechanisms	mechanism	NNS
cord-032504-tmohg1mj	241	14	and	and	CC
cord-032504-tmohg1mj	241	15	modulation	modulation	NN
cord-032504-tmohg1mj	241	16	by	by	IN
cord-032504-tmohg1mj	241	17	adjunctive	adjunctive	JJ
cord-032504-tmohg1mj	241	18	cytokine	cytokine	NN
cord-032504-tmohg1mj	241	19	therapy	therapy	NN
cord-032504-tmohg1mj	241	20	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	241	21	buds	bud	NNS
cord-032504-tmohg1mj	241	22	and	and	CC
cord-032504-tmohg1mj	241	23	accumulates	accumulate	VBZ
cord-032504-tmohg1mj	241	24	in	in	IN
cord-032504-tmohg1mj	241	25	"	"	``
cord-032504-tmohg1mj	241	26	nonacidic	nonacidic	JJ
cord-032504-tmohg1mj	241	27	"	"	''
cord-032504-tmohg1mj	241	28	endosomes	endosome	NNS
cord-032504-tmohg1mj	241	29	of	of	IN
cord-032504-tmohg1mj	241	30	macrophages	macrophage	NNS
cord-032504-tmohg1mj	241	31	Impairment	impairment	NN
cord-032504-tmohg1mj	241	32	of	of	IN
cord-032504-tmohg1mj	241	33	phagosome	phagosome	NN
cord-032504-tmohg1mj	241	34	-	-	HYPH
cord-032504-tmohg1mj	241	35	lysosome	lysosome	NN
cord-032504-tmohg1mj	241	36	fusion	fusion	NN
cord-032504-tmohg1mj	241	37	in	in	IN
cord-032504-tmohg1mj	241	38	HIV-1-infected	hiv-1-infecte	VBN
cord-032504-tmohg1mj	241	39	macrophages	macrophage	NNS
cord-032504-tmohg1mj	242	1	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	242	2	Tat	Tat	NNP
cord-032504-tmohg1mj	242	3	alters	alter	VBZ
cord-032504-tmohg1mj	242	4	neuronal	neuronal	JJ
cord-032504-tmohg1mj	242	5	autophagy	autophagy	NN
cord-032504-tmohg1mj	242	6	by	by	IN
cord-032504-tmohg1mj	242	7	modulating	modulate	VBG
cord-032504-tmohg1mj	242	8	autophagosome	autophagosome	JJ
cord-032504-tmohg1mj	242	9	fusion	fusion	NN
cord-032504-tmohg1mj	242	10	to	to	IN
cord-032504-tmohg1mj	242	11	the	the	DT
cord-032504-tmohg1mj	242	12	lysosome	lysosome	NN
cord-032504-tmohg1mj	242	13	:	:	:
cord-032504-tmohg1mj	242	14	implications	implication	NNS
cord-032504-tmohg1mj	242	15	for	for	IN
cord-032504-tmohg1mj	242	16	HIV	HIV	NNP
cord-032504-tmohg1mj	242	17	-	-	HYPH
cord-032504-tmohg1mj	242	18	associated	associate	VBN
cord-032504-tmohg1mj	242	19	neurocognitive	neurocognitive	JJ
cord-032504-tmohg1mj	242	20	disorders	disorder	NNS
cord-032504-tmohg1mj	243	1	The	the	DT
cord-032504-tmohg1mj	243	2	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	243	3	protein	protein	NN
cord-032504-tmohg1mj	243	4	Vpr	Vpr	NNP
cord-032504-tmohg1mj	243	5	impairs	impair	VBZ
cord-032504-tmohg1mj	243	6	phagosome	phagosome	NN
cord-032504-tmohg1mj	243	7	maturation	maturation	NN
cord-032504-tmohg1mj	243	8	by	by	IN
cord-032504-tmohg1mj	243	9	controlling	control	VBG
cord-032504-tmohg1mj	243	10	microtubule	microtubule	NN
cord-032504-tmohg1mj	243	11	-	-	HYPH
cord-032504-tmohg1mj	243	12	dependent	dependent	JJ
cord-032504-tmohg1mj	243	13	trafficking	traffic	VBG
cord-032504-tmohg1mj	243	14	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	243	15	enhances	enhance	VBZ
cord-032504-tmohg1mj	243	16	mTORC1	mtorc1	JJ
cord-032504-tmohg1mj	243	17	activity	activity	NN
cord-032504-tmohg1mj	243	18	and	and	CC
cord-032504-tmohg1mj	243	19	repositions	reposition	VBZ
cord-032504-tmohg1mj	243	20	lysosomes	lysosome	NNS
cord-032504-tmohg1mj	243	21	to	to	IN
cord-032504-tmohg1mj	243	22	the	the	DT
cord-032504-tmohg1mj	243	23	periphery	periphery	NN
cord-032504-tmohg1mj	243	24	by	by	IN
cord-032504-tmohg1mj	243	25	co	co	JJ
cord-032504-tmohg1mj	243	26	-	-	JJ
cord-032504-tmohg1mj	243	27	opting	opting	JJ
cord-032504-tmohg1mj	243	28	Rag	Rag	NNP
cord-032504-tmohg1mj	243	29	GTPases	gtpase	NNS
cord-032504-tmohg1mj	243	30	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	243	31	infection	infection	NN
cord-032504-tmohg1mj	243	32	of	of	IN
cord-032504-tmohg1mj	243	33	macrophages	macrophage	NNS
cord-032504-tmohg1mj	243	34	dysregulates	dysregulates	NNP
cord-032504-tmohg1mj	243	35	innate	innate	VBP
cord-032504-tmohg1mj	243	36	immune	immune	JJ
cord-032504-tmohg1mj	243	37	responses	response	NNS
cord-032504-tmohg1mj	243	38	to	to	IN
cord-032504-tmohg1mj	243	39	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	243	40	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	243	41	by	by	IN
cord-032504-tmohg1mj	243	42	inhibition	inhibition	NN
cord-032504-tmohg1mj	243	43	of	of	IN
cord-032504-tmohg1mj	243	44	interleukin-10	interleukin-10	NNP
cord-032504-tmohg1mj	243	45	IL-10	IL-10	NNP
cord-032504-tmohg1mj	243	46	blocks	block	VBZ
cord-032504-tmohg1mj	243	47	phagosome	phagosome	NN
cord-032504-tmohg1mj	243	48	maturation	maturation	NN
cord-032504-tmohg1mj	243	49	in	in	IN
cord-032504-tmohg1mj	243	50	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	243	51	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	243	52	-	-	HYPH
cord-032504-tmohg1mj	243	53	infected	infect	VBN
cord-032504-tmohg1mj	243	54	human	human	JJ
cord-032504-tmohg1mj	243	55	macrophages	macrophage	NNS
cord-032504-tmohg1mj	244	1	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	244	2	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	244	3	resides	reside	VBZ
cord-032504-tmohg1mj	244	4	in	in	IN
cord-032504-tmohg1mj	244	5	nonacidified	nonacidified	JJ
cord-032504-tmohg1mj	244	6	vacuoles	vacuole	NNS
cord-032504-tmohg1mj	244	7	in	in	IN
cord-032504-tmohg1mj	244	8	endocytically	endocytically	RB
cord-032504-tmohg1mj	244	9	competent	competent	JJ
cord-032504-tmohg1mj	244	10	alveolar	alveolar	JJ
cord-032504-tmohg1mj	244	11	macrophages	macrophage	NNS
cord-032504-tmohg1mj	244	12	from	from	IN
cord-032504-tmohg1mj	244	13	patients	patient	NNS
cord-032504-tmohg1mj	244	14	with	with	IN
cord-032504-tmohg1mj	244	15	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	244	16	and	and	CC
cord-032504-tmohg1mj	244	17	HIV	HIV	NNP
cord-032504-tmohg1mj	244	18	infection	infection	NN
cord-032504-tmohg1mj	244	19	Endosomal	Endosomal	NNP
cord-032504-tmohg1mj	244	20	membrane	membrane	NN
cord-032504-tmohg1mj	244	21	traffic	traffic	NN
cord-032504-tmohg1mj	244	22	:	:	:
cord-032504-tmohg1mj	245	1	convergence	convergence	NNP
cord-032504-tmohg1mj	245	2	point	point	NN
cord-032504-tmohg1mj	245	3	targeted	target	VBN
cord-032504-tmohg1mj	245	4	by	by	IN
cord-032504-tmohg1mj	245	5	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	245	6	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	245	7	and	and	CC
cord-032504-tmohg1mj	245	8	HIV	HIV	NNP
cord-032504-tmohg1mj	245	9	Apoptosis	Apoptosis	NNP
cord-032504-tmohg1mj	245	10	is	be	VBZ
cord-032504-tmohg1mj	245	11	an	an	DT
cord-032504-tmohg1mj	245	12	innate	innate	JJ
cord-032504-tmohg1mj	245	13	defense	defense	NN
cord-032504-tmohg1mj	245	14	function	function	NN
cord-032504-tmohg1mj	245	15	of	of	IN
cord-032504-tmohg1mj	245	16	macrophages	macrophage	NNS
cord-032504-tmohg1mj	245	17	against	against	IN
cord-032504-tmohg1mj	245	18	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	245	19	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	245	20	Cell	cell	NN
cord-032504-tmohg1mj	245	21	death	death	NN
cord-032504-tmohg1mj	245	22	and	and	CC
cord-032504-tmohg1mj	245	23	autophagy	autophagy	NN
cord-032504-tmohg1mj	245	24	in	in	IN
cord-032504-tmohg1mj	245	25	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	246	1	HIV	HIV	NNP
cord-032504-tmohg1mj	246	2	-	-	HYPH
cord-032504-tmohg1mj	246	3	related	relate	VBN
cord-032504-tmohg1mj	246	4	proteins	protein	NNS
cord-032504-tmohg1mj	246	5	prolong	prolong	VBP
cord-032504-tmohg1mj	246	6	macrophage	macrophage	NN
cord-032504-tmohg1mj	246	7	survival	survival	NN
cord-032504-tmohg1mj	246	8	through	through	IN
cord-032504-tmohg1mj	246	9	induction	induction	NN
cord-032504-tmohg1mj	246	10	of	of	IN
cord-032504-tmohg1mj	246	11	Triggering	trigger	VBG
cord-032504-tmohg1mj	246	12	receptor	receptor	NN
cord-032504-tmohg1mj	246	13	expressed	express	VBN
cord-032504-tmohg1mj	246	14	on	on	IN
cord-032504-tmohg1mj	246	15	myeloid	myeloid	JJ
cord-032504-tmohg1mj	246	16	cells-1	cells-1	NNP
cord-032504-tmohg1mj	246	17	Human	human	JJ
cord-032504-tmohg1mj	246	18	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	246	19	virus	virus	NN
cord-032504-tmohg1mj	246	20	type	type	NN
cord-032504-tmohg1mj	246	21	1	1	CD
cord-032504-tmohg1mj	246	22	Nef	Nef	NNP
cord-032504-tmohg1mj	246	23	inhibits	inhibit	VBZ
cord-032504-tmohg1mj	246	24	autophagy	autophagy	NN
cord-032504-tmohg1mj	246	25	through	through	IN
cord-032504-tmohg1mj	246	26	transcription	transcription	NN
cord-032504-tmohg1mj	246	27	factor	factor	NN
cord-032504-tmohg1mj	246	28	EB	EB	NNP
cord-032504-tmohg1mj	246	29	sequestration	sequestration	NN
cord-032504-tmohg1mj	246	30	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	246	31	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	246	32	and	and	CC
cord-032504-tmohg1mj	246	33	human	human	JJ
cord-032504-tmohg1mj	246	34	immunodeficiency	immunodeficiency	NN
cord-032504-tmohg1mj	246	35	virus	virus	NN
cord-032504-tmohg1mj	246	36	type	type	NN
cord-032504-tmohg1mj	246	37	1	1	CD
cord-032504-tmohg1mj	246	38	cooperatively	cooperatively	RB
cord-032504-tmohg1mj	246	39	modulate	modulate	VBP
cord-032504-tmohg1mj	246	40	macrophage	macrophage	NN
cord-032504-tmohg1mj	246	41	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	246	42	via	via	IN
cord-032504-tmohg1mj	246	43	toll	toll	NN
cord-032504-tmohg1mj	246	44	like	like	IN
cord-032504-tmohg1mj	246	45	receptor	receptor	NN
cord-032504-tmohg1mj	246	46	2	2	CD
cord-032504-tmohg1mj	246	47	and	and	CC
cord-032504-tmohg1mj	246	48	calcium	calcium	NN
cord-032504-tmohg1mj	246	49	homeostasis	homeostasis	NN
cord-032504-tmohg1mj	247	1	HIV	HIV	NNP
cord-032504-tmohg1mj	247	2	gp120	gp120	NNP
cord-032504-tmohg1mj	247	3	in	in	IN
cord-032504-tmohg1mj	247	4	the	the	DT
cord-032504-tmohg1mj	247	5	lungs	lung	NNS
cord-032504-tmohg1mj	247	6	of	of	IN
cord-032504-tmohg1mj	247	7	antiretroviral	antiretroviral	JJ
cord-032504-tmohg1mj	247	8	therapy	therapy	NN
cord-032504-tmohg1mj	247	9	-	-	HYPH
cord-032504-tmohg1mj	247	10	treated	treat	VBN
cord-032504-tmohg1mj	247	11	individuals	individual	NNS
cord-032504-tmohg1mj	247	12	impairs	impair	VBZ
cord-032504-tmohg1mj	247	13	alveolar	alveolar	JJ
cord-032504-tmohg1mj	247	14	macrophage	macrophage	NN
cord-032504-tmohg1mj	247	15	responses	response	NNS
cord-032504-tmohg1mj	247	16	to	to	IN
cord-032504-tmohg1mj	247	17	pneumococci	pneumococci	NNP
cord-032504-tmohg1mj	247	18	Impaired	impair	VBN
cord-032504-tmohg1mj	247	19	M.	M.	NNP
cord-032504-tmohg1mj	247	20	tuberculosismediated	tuberculosismediated	JJ
cord-032504-tmohg1mj	247	21	apoptosis	apoptosis	NN
cord-032504-tmohg1mj	247	22	in	in	IN
cord-032504-tmohg1mj	247	23	alveolar	alveolar	JJ
cord-032504-tmohg1mj	247	24	macrophages	macrophage	NNS
cord-032504-tmohg1mj	247	25	from	from	IN
cord-032504-tmohg1mj	247	26	HIV	HIV	NNP
cord-032504-tmohg1mj	247	27	+	+	CC
cord-032504-tmohg1mj	247	28	persons	person	NNS
cord-032504-tmohg1mj	247	29	:	:	:
cord-032504-tmohg1mj	247	30	potential	potential	JJ
cord-032504-tmohg1mj	247	31	role	role	NN
cord-032504-tmohg1mj	247	32	of	of	IN
cord-032504-tmohg1mj	248	1	IL-10	IL-10	NNP
cord-032504-tmohg1mj	248	2	and	and	CC
cord-032504-tmohg1mj	248	3	BCL-3	BCL-3	NNP
cord-032504-tmohg1mj	249	1	All	all	DT
cord-032504-tmohg1mj	249	2	-	-	HYPH
cord-032504-tmohg1mj	249	3	trans	trans	NNP
cord-032504-tmohg1mj	249	4	retinoic	retinoic	JJ
cord-032504-tmohg1mj	249	5	acid	acid	NN
cord-032504-tmohg1mj	249	6	augments	augment	VBZ
cord-032504-tmohg1mj	249	7	autophagy	autophagy	NN
cord-032504-tmohg1mj	249	8	during	during	IN
cord-032504-tmohg1mj	249	9	intracellular	intracellular	JJ
cord-032504-tmohg1mj	249	10	bacterial	bacterial	JJ
cord-032504-tmohg1mj	249	11	infection	infection	NN
cord-032504-tmohg1mj	249	12	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	249	13	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	249	14	infects	infect	VBZ
cord-032504-tmohg1mj	249	15	dendritic	dendritic	JJ
cord-032504-tmohg1mj	249	16	cells	cell	NNS
cord-032504-tmohg1mj	249	17	with	with	IN
cord-032504-tmohg1mj	249	18	high	high	JJ
cord-032504-tmohg1mj	249	19	frequency	frequency	NN
cord-032504-tmohg1mj	249	20	and	and	CC
cord-032504-tmohg1mj	249	21	impairs	impair	VBZ
cord-032504-tmohg1mj	249	22	their	-PRON-	PRP$
cord-032504-tmohg1mj	249	23	function	function	NN
cord-032504-tmohg1mj	249	24	in	in	IN
cord-032504-tmohg1mj	249	25	vivo	vivo	NNP
cord-032504-tmohg1mj	249	26	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	249	27	Nef	Nef	NNP
cord-032504-tmohg1mj	249	28	impairs	impair	VBZ
cord-032504-tmohg1mj	250	1	MHC	MHC	NNP
cord-032504-tmohg1mj	250	2	class	class	NN
cord-032504-tmohg1mj	250	3	II	II	NNP
cord-032504-tmohg1mj	250	4	antigen	antigen	NN
cord-032504-tmohg1mj	250	5	presentation	presentation	NN
cord-032504-tmohg1mj	250	6	and	and	CC
cord-032504-tmohg1mj	250	7	surface	surface	NN
cord-032504-tmohg1mj	250	8	expression	expression	NN
cord-032504-tmohg1mj	250	9	Nef	Nef	NNP
cord-032504-tmohg1mj	250	10	alleles	allele	NNS
cord-032504-tmohg1mj	250	11	from	from	IN
cord-032504-tmohg1mj	250	12	children	child	NNS
cord-032504-tmohg1mj	250	13	with	with	IN
cord-032504-tmohg1mj	250	14	non	non	JJ
cord-032504-tmohg1mj	250	15	-	-	JJ
cord-032504-tmohg1mj	250	16	progressive	progressive	JJ
cord-032504-tmohg1mj	250	17	HIV-1	HIV-1	NNP
cord-032504-tmohg1mj	250	18	infection	infection	NN
cord-032504-tmohg1mj	250	19	modulate	modulate	VBP
cord-032504-tmohg1mj	250	20	MHC	MHC	NNP
cord-032504-tmohg1mj	250	21	-	-	HYPH
cord-032504-tmohg1mj	250	22	II	II	NNP
cord-032504-tmohg1mj	250	23	expression	expression	NN
cord-032504-tmohg1mj	250	24	more	more	RBR
cord-032504-tmohg1mj	250	25	efficiently	efficiently	RB
cord-032504-tmohg1mj	250	26	than	than	IN
cord-032504-tmohg1mj	250	27	those	those	DT
cord-032504-tmohg1mj	250	28	from	from	IN
cord-032504-tmohg1mj	250	29	rapid	rapid	JJ
cord-032504-tmohg1mj	250	30	progressors	progressor	NNS
cord-032504-tmohg1mj	250	31	HIV	HIV	NNP
cord-032504-tmohg1mj	250	32	interferes	interfere	VBZ
cord-032504-tmohg1mj	250	33	with	with	IN
cord-032504-tmohg1mj	250	34	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	250	35	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	36	antigen	antigen	NN
cord-032504-tmohg1mj	250	37	presentation	presentation	NN
cord-032504-tmohg1mj	250	38	in	in	IN
cord-032504-tmohg1mj	250	39	human	human	JJ
cord-032504-tmohg1mj	250	40	dendritic	dendritic	JJ
cord-032504-tmohg1mj	250	41	cells	cell	NNS
cord-032504-tmohg1mj	250	42	Analysis	Analysis	NNP
cord-032504-tmohg1mj	250	43	of	of	IN
cord-032504-tmohg1mj	250	44	18FDG	18FDG	NNP
cord-032504-tmohg1mj	250	45	PET	PET	NNP
cord-032504-tmohg1mj	250	46	/	/	SYM
cord-032504-tmohg1mj	250	47	CT	CT	NNP
cord-032504-tmohg1mj	250	48	imaging	imaging	NN
cord-032504-tmohg1mj	250	49	as	as	IN
cord-032504-tmohg1mj	250	50	a	a	DT
cord-032504-tmohg1mj	250	51	tool	tool	NN
cord-032504-tmohg1mj	250	52	for	for	IN
cord-032504-tmohg1mj	250	53	studying	study	VBG
cord-032504-tmohg1mj	250	54	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	250	55	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	56	infection	infection	NN
cord-032504-tmohg1mj	250	57	and	and	CC
cord-032504-tmohg1mj	250	58	treatment	treatment	NN
cord-032504-tmohg1mj	250	59	in	in	IN
cord-032504-tmohg1mj	250	60	non	non	JJ
cord-032504-tmohg1mj	250	61	-	-	JJ
cord-032504-tmohg1mj	250	62	human	human	JJ
cord-032504-tmohg1mj	250	63	primates	primate	NNS
cord-032504-tmohg1mj	250	64	Sterilization	Sterilization	NNP
cord-032504-tmohg1mj	250	65	of	of	IN
cord-032504-tmohg1mj	250	66	granulomas	granuloma	NNS
cord-032504-tmohg1mj	250	67	is	be	VBZ
cord-032504-tmohg1mj	250	68	common	common	JJ
cord-032504-tmohg1mj	250	69	in	in	IN
cord-032504-tmohg1mj	250	70	active	active	JJ
cord-032504-tmohg1mj	250	71	and	and	CC
cord-032504-tmohg1mj	250	72	latent	latent	JJ
cord-032504-tmohg1mj	250	73	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	74	despite	despite	IN
cord-032504-tmohg1mj	250	75	within	within	IN
cord-032504-tmohg1mj	250	76	-	-	HYPH
cord-032504-tmohg1mj	250	77	host	host	NN
cord-032504-tmohg1mj	250	78	variability	variability	NN
cord-032504-tmohg1mj	250	79	in	in	IN
cord-032504-tmohg1mj	250	80	bacterial	bacterial	JJ
cord-032504-tmohg1mj	250	81	killing	kill	VBG
cord-032504-tmohg1mj	250	82	Characterization	characterization	NN
cord-032504-tmohg1mj	250	83	of	of	IN
cord-032504-tmohg1mj	250	84	progressive	progressive	JJ
cord-032504-tmohg1mj	250	85	HIV	HIV	NNP
cord-032504-tmohg1mj	250	86	-	-	HYPH
cord-032504-tmohg1mj	250	87	associated	associate	VBN
cord-032504-tmohg1mj	250	88	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	89	using	use	VBG
cord-032504-tmohg1mj	250	90	2-deoxy-2-[18	2-deoxy-2-[18	CD
cord-032504-tmohg1mj	250	91	F	F	NNP
cord-032504-tmohg1mj	250	92	]	]	-RRB-
cord-032504-tmohg1mj	250	93	fluoro	fluoro	NNP
cord-032504-tmohg1mj	250	94	-	-	HYPH
cord-032504-tmohg1mj	250	95	d	d	NN
cord-032504-tmohg1mj	250	96	-	-	HYPH
cord-032504-tmohg1mj	250	97	glucose	glucose	NN
cord-032504-tmohg1mj	250	98	positron	positron	NN
cord-032504-tmohg1mj	250	99	emission	emission	NN
cord-032504-tmohg1mj	250	100	and	and	CC
cord-032504-tmohg1mj	250	101	computed	compute	VBN
cord-032504-tmohg1mj	250	102	tomography	tomography	NN
cord-032504-tmohg1mj	250	103	Prospective	prospective	JJ
cord-032504-tmohg1mj	250	104	discrimination	discrimination	NN
cord-032504-tmohg1mj	250	105	of	of	IN
cord-032504-tmohg1mj	250	106	controllers	controller	NNS
cord-032504-tmohg1mj	250	107	from	from	IN
cord-032504-tmohg1mj	250	108	progressors	progressor	NNS
cord-032504-tmohg1mj	250	109	early	early	RB
cord-032504-tmohg1mj	250	110	after	after	IN
cord-032504-tmohg1mj	250	111	low	low	JJ
cord-032504-tmohg1mj	250	112	-	-	HYPH
cord-032504-tmohg1mj	250	113	dose	dose	NN
cord-032504-tmohg1mj	250	114	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	250	115	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	116	infection	infection	NN
cord-032504-tmohg1mj	250	117	of	of	IN
cord-032504-tmohg1mj	250	118	cynomolgus	cynomolgus	JJ
cord-032504-tmohg1mj	250	119	macaques	macaque	NNS
cord-032504-tmohg1mj	250	120	using	use	VBG
cord-032504-tmohg1mj	250	121	blood	blood	NN
cord-032504-tmohg1mj	250	122	RNA	RNA	NNP
cord-032504-tmohg1mj	250	123	signatures	signature	NNS
cord-032504-tmohg1mj	250	124	Four	four	CD
cord-032504-tmohg1mj	250	125	-	-	HYPH
cord-032504-tmohg1mj	250	126	gene	gene	NN
cord-032504-tmohg1mj	250	127	pan	pan	JJ
cord-032504-tmohg1mj	250	128	-	-	JJ
cord-032504-tmohg1mj	250	129	African	african	JJ
cord-032504-tmohg1mj	250	130	Blood	Blood	NNP
cord-032504-tmohg1mj	250	131	signature	signature	NN
cord-032504-tmohg1mj	250	132	predicts	predict	VBZ
cord-032504-tmohg1mj	250	133	progression	progression	NN
cord-032504-tmohg1mj	250	134	to	to	IN
cord-032504-tmohg1mj	250	135	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	136	A	a	DT
cord-032504-tmohg1mj	250	137	blood	blood	NN
cord-032504-tmohg1mj	250	138	RNA	rna	NN
cord-032504-tmohg1mj	250	139	signature	signature	NN
cord-032504-tmohg1mj	250	140	for	for	IN
cord-032504-tmohg1mj	250	141	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	250	142	disease	disease	NN
cord-032504-tmohg1mj	250	143	risk	risk	NN
cord-032504-tmohg1mj	250	144	:	:	:
cord-032504-tmohg1mj	251	1	a	a	DT
cord-032504-tmohg1mj	251	2	prospective	prospective	JJ
cord-032504-tmohg1mj	251	3	cohort	cohort	NN
cord-032504-tmohg1mj	251	4	study	study	NN
cord-032504-tmohg1mj	251	5	A	a	DT
cord-032504-tmohg1mj	251	6	high	high	JJ
cord-032504-tmohg1mj	251	7	throughput	throughput	NN
cord-032504-tmohg1mj	251	8	whole	whole	JJ
cord-032504-tmohg1mj	251	9	blood	blood	NN
cord-032504-tmohg1mj	251	10	assay	assay	NN
cord-032504-tmohg1mj	251	11	for	for	IN
cord-032504-tmohg1mj	251	12	analysis	analysis	NN
cord-032504-tmohg1mj	251	13	of	of	IN
cord-032504-tmohg1mj	251	14	multiple	multiple	JJ
cord-032504-tmohg1mj	251	15	antigenspecific	antigenspecific	NN
cord-032504-tmohg1mj	251	16	T	T	NNP
cord-032504-tmohg1mj	251	17	Cell	Cell	NNP
cord-032504-tmohg1mj	251	18	responses	response	NNS
cord-032504-tmohg1mj	251	19	in	in	IN
cord-032504-tmohg1mj	251	20	human	human	JJ
cord-032504-tmohg1mj	251	21	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	251	22	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	251	23	infection	infection	NN
cord-032504-tmohg1mj	251	24	Plasma	plasma	NN
cord-032504-tmohg1mj	251	25	metabolomics	metabolomic	NNS
cord-032504-tmohg1mj	251	26	in	in	IN
cord-032504-tmohg1mj	251	27	human	human	JJ
cord-032504-tmohg1mj	251	28	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	251	29	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	251	30	disease	disease	NN
cord-032504-tmohg1mj	251	31	:	:	:
cord-032504-tmohg1mj	251	32	a	a	DT
cord-032504-tmohg1mj	251	33	pilot	pilot	NN
cord-032504-tmohg1mj	251	34	study	study	NN
cord-032504-tmohg1mj	251	35	High	high	JJ
cord-032504-tmohg1mj	251	36	-	-	HYPH
cord-032504-tmohg1mj	251	37	resolution	resolution	NN
cord-032504-tmohg1mj	251	38	plasma	plasma	NN
cord-032504-tmohg1mj	251	39	metabolomics	metabolomic	NNS
cord-032504-tmohg1mj	251	40	analysis	analysis	NN
cord-032504-tmohg1mj	251	41	to	to	TO
cord-032504-tmohg1mj	251	42	detect	detect	VB
cord-032504-tmohg1mj	251	43	Mycobacterium	Mycobacterium	NNP
cord-032504-tmohg1mj	251	44	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	251	45	-	-	HYPH
cord-032504-tmohg1mj	251	46	associated	associate	VBN
cord-032504-tmohg1mj	251	47	metabolites	metabolite	NNS
cord-032504-tmohg1mj	251	48	that	that	WDT
cord-032504-tmohg1mj	251	49	distinguish	distinguish	VBP
cord-032504-tmohg1mj	251	50	active	active	JJ
cord-032504-tmohg1mj	251	51	pulmonary	pulmonary	JJ
cord-032504-tmohg1mj	251	52	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	251	53	in	in	IN
cord-032504-tmohg1mj	251	54	humans	human	NNS
cord-032504-tmohg1mj	252	1	Metabolite	metabolite	JJ
cord-032504-tmohg1mj	252	2	changes	change	NNS
cord-032504-tmohg1mj	252	3	in	in	IN
cord-032504-tmohg1mj	252	4	blood	blood	NN
cord-032504-tmohg1mj	252	5	predict	predict	VBP
cord-032504-tmohg1mj	252	6	the	the	DT
cord-032504-tmohg1mj	252	7	onset	onset	NN
cord-032504-tmohg1mj	252	8	of	of	IN
cord-032504-tmohg1mj	252	9	tuberculosis	tuberculosis	NN
cord-032504-tmohg1mj	252	10	Springer	Springer	NNP
cord-032504-tmohg1mj	252	11	Nature	Nature	NNP
cord-032504-tmohg1mj	252	12	remains	remain	VBZ
cord-032504-tmohg1mj	252	13	neutral	neutral	JJ
cord-032504-tmohg1mj	252	14	with	with	IN
cord-032504-tmohg1mj	252	15	regard	regard	NN
cord-032504-tmohg1mj	252	16	to	to	IN
cord-032504-tmohg1mj	252	17	jurisdictional	jurisdictional	JJ
cord-032504-tmohg1mj	252	18	claims	claim	NNS
cord-032504-tmohg1mj	252	19	in	in	IN
cord-032504-tmohg1mj	252	20	published	publish	VBN
cord-032504-tmohg1mj	252	21	maps	map	NNS
cord-032504-tmohg1mj	252	22	and	and	CC
cord-032504-tmohg1mj	252	23	institutional	institutional	JJ
cord-032504-tmohg1mj	252	24	affiliations	affiliation	NNS
cord-032504-tmohg1mj	253	1	We	-PRON-	PRP
cord-032504-tmohg1mj	253	2	would	would	MD
cord-032504-tmohg1mj	253	3	like	like	VB
cord-032504-tmohg1mj	253	4	to	to	TO
cord-032504-tmohg1mj	253	5	thank	thank	VB
cord-032504-tmohg1mj	253	6	our	-PRON-	PRP$
cord-032504-tmohg1mj	253	7	colleague	colleague	NN
cord-032504-tmohg1mj	253	8	Cheryl	Cheryl	NNP
cord-032504-tmohg1mj	253	9	L.	L.	NNP
cord-032504-tmohg1mj	253	10	Day	Day	NNP
cord-032504-tmohg1mj	253	11	,	,	,
cord-032504-tmohg1mj	253	12	PhD	PhD	NNP
cord-032504-tmohg1mj	253	13	,	,	,
cord-032504-tmohg1mj	253	14	for	for	IN
cord-032504-tmohg1mj	253	15	review	review	NN
cord-032504-tmohg1mj	253	16	,	,	,
cord-032504-tmohg1mj	253	17	thoughtful	thoughtful	JJ
cord-032504-tmohg1mj	253	18	discussion	discussion	NN
cord-032504-tmohg1mj	253	19	,	,	,
cord-032504-tmohg1mj	253	20	and	and	CC
cord-032504-tmohg1mj	253	21	feedback	feedback	VB
cord-032504-tmohg1mj	253	22	on	on	IN
cord-032504-tmohg1mj	253	23	this	this	DT
cord-032504-tmohg1mj	253	24	manuscript	manuscript	NN
cord-032504-tmohg1mj	253	25	.	.	.
cord-032504-tmohg1mj	254	1	SCA	SCA	NNP
cord-032504-tmohg1mj	254	2	and	and	CC
cord-032504-tmohg1mj	254	3	BSS	BSS	NNP
cord-032504-tmohg1mj	254	4	conceived	conceive	VBD
cord-032504-tmohg1mj	254	5	of	of	IN
cord-032504-tmohg1mj	254	6	the	the	DT
cord-032504-tmohg1mj	254	7	review	review	NN
cord-032504-tmohg1mj	254	8	,	,	,
cord-032504-tmohg1mj	254	9	drafted	draft	VBN
cord-032504-tmohg1mj	254	10	and	and	CC
cord-032504-tmohg1mj	254	11	revised	revise	VBD
cord-032504-tmohg1mj	254	12	the	the	DT
cord-032504-tmohg1mj	254	13	manuscript	manuscript	NN
cord-032504-tmohg1mj	254	14	.	.	.
cord-032504-tmohg1mj	255	1	Both	both	DT
cord-032504-tmohg1mj	255	2	authors	author	NNS
cord-032504-tmohg1mj	255	3	read	read	VBP
cord-032504-tmohg1mj	255	4	and	and	CC
cord-032504-tmohg1mj	255	5	approved	approve	VBD
cord-032504-tmohg1mj	255	6	the	the	DT
cord-032504-tmohg1mj	255	7	final	final	JJ
cord-032504-tmohg1mj	255	8	manuscript	manuscript	NN
cord-032504-tmohg1mj	255	9	.	.	.
cord-032504-tmohg1mj	256	1	This	this	DT
cord-032504-tmohg1mj	256	2	work	work	NN
cord-032504-tmohg1mj	256	3	was	be	VBD
cord-032504-tmohg1mj	256	4	supported	support	VBN
cord-032504-tmohg1mj	256	5	by	by	IN
cord-032504-tmohg1mj	256	6	the	the	DT
cord-032504-tmohg1mj	256	7	following	follow	VBG
cord-032504-tmohg1mj	256	8	grants	grant	NNS
cord-032504-tmohg1mj	256	9	:	:	:
cord-032504-tmohg1mj	257	1	NIH	NIH	NNP
cord-032504-tmohg1mj	257	2	/	/	SYM
cord-032504-tmohg1mj	257	3	NIAID	NIAID	NNP
cord-032504-tmohg1mj	257	4	K23	K23	NNP
cord-032504-tmohg1mj	257	5	AI134182	AI134182	NNP