id	sid	tid	token	lemma	pos
cord-010499-yefxrj30	1	1	key	key	NN
cord-010499-yefxrj30	1	2	:	:	:
cord-010499-yefxrj30	2	1	cord-010499-yefxrj30	cord-010499-yefxrj30	NNS
cord-010499-yefxrj30	2	2	authors	author	NNS
cord-010499-yefxrj30	2	3	:	:	:
cord-010499-yefxrj30	2	4	Yelverton	Yelverton	NNP
cord-010499-yefxrj30	2	5	,	,	,
cord-010499-yefxrj30	2	6	Elizabeth	Elizabeth	NNP
cord-010499-yefxrj30	2	7	;	;	:
cord-010499-yefxrj30	2	8	Lindsley	Lindsley	NNP
cord-010499-yefxrj30	2	9	,	,	,
cord-010499-yefxrj30	2	10	Dale	Dale	NNP
cord-010499-yefxrj30	2	11	;	;	:
cord-010499-yefxrj30	2	12	Yamauchi	Yamauchi	NNP
cord-010499-yefxrj30	2	13	,	,	,
cord-010499-yefxrj30	2	14	Phil	Phil	NNP
cord-010499-yefxrj30	2	15	;	;	:
cord-010499-yefxrj30	2	16	Gallant	Gallant	NNP
cord-010499-yefxrj30	2	17	,	,	,
cord-010499-yefxrj30	2	18	Jonathan	Jonathan	NNP
cord-010499-yefxrj30	2	19	A.	a.	NN
cord-010499-yefxrj30	2	20	title	title	NN
cord-010499-yefxrj30	2	21	:	:	:
cord-010499-yefxrj30	3	1	The	the	DT
cord-010499-yefxrj30	3	2	function	function	NN
cord-010499-yefxrj30	3	3	of	of	IN
cord-010499-yefxrj30	3	4	a	a	DT
cord-010499-yefxrj30	3	5	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	3	6	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	3	7	signal	signal	NN
cord-010499-yefxrj30	3	8	from	from	IN
cord-010499-yefxrj30	3	9	human	human	JJ
cord-010499-yefxrj30	3	10	immunodeficiency	immunodeficiency	NN
cord-010499-yefxrj30	3	11	virus‐1	virus‐1	NNP
cord-010499-yefxrj30	3	12	in	in	IN
cord-010499-yefxrj30	3	13	Escherichia	Escherichia	NNP
cord-010499-yefxrj30	3	14	coli	coli	NNS
cord-010499-yefxrj30	3	15	date	date	NN
cord-010499-yefxrj30	3	16	:	:	:
cord-010499-yefxrj30	3	17	2006	2006	CD
cord-010499-yefxrj30	3	18	-	-	SYM
cord-010499-yefxrj30	3	19	10	10	CD
cord-010499-yefxrj30	3	20	-	-	SYM
cord-010499-yefxrj30	3	21	27	27	CD
cord-010499-yefxrj30	3	22	journal	journal	NN
cord-010499-yefxrj30	3	23	:	:	:
cord-010499-yefxrj30	4	1	Mol	Mol	NNP
cord-010499-yefxrj30	4	2	Microbiol	Microbiol	NNP
cord-010499-yefxrj30	4	3	DOI	DOI	NNP
cord-010499-yefxrj30	4	4	:	:	:
cord-010499-yefxrj30	5	1	10.1111	10.1111	CD
cord-010499-yefxrj30	5	2	/	/	SYM
cord-010499-yefxrj30	5	3	j.1365	j.1365	XX
cord-010499-yefxrj30	5	4	-	-	HYPH
cord-010499-yefxrj30	5	5	2958.1994.tb00310.x	2958.1994.tb00310.x	CD
cord-010499-yefxrj30	5	6	sha	sha	NN
cord-010499-yefxrj30	5	7	:	:	:
cord-010499-yefxrj30	5	8	325e50e217cb21ebe9e8b3899f1e3d5f1d8f7650	325e50e217cb21ebe9e8b3899f1e3d5f1d8f7650	CD
cord-010499-yefxrj30	5	9	doc_id	doc_id	CD
cord-010499-yefxrj30	5	10	:	:	:
cord-010499-yefxrj30	5	11	10499	10499	CD
cord-010499-yefxrj30	5	12	cord_uid	cord_uid	NNS
cord-010499-yefxrj30	5	13	:	:	:
cord-010499-yefxrj30	6	1	yefxrj30	yefxrj30	NNP
cord-010499-yefxrj30	7	1	A	a	DT
cord-010499-yefxrj30	7	2	15‐17	15‐17	JJ
cord-010499-yefxrj30	7	3	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	7	4	sequence	sequence	NN
cord-010499-yefxrj30	7	5	from	from	IN
cord-010499-yefxrj30	7	6	the	the	DT
cord-010499-yefxrj30	7	7	gag‐pol	gag‐pol	NN
cord-010499-yefxrj30	7	8	ribosome	ribosome	NN
cord-010499-yefxrj30	7	9	frameshift	frameshift	NN
cord-010499-yefxrj30	7	10	site	site	NN
cord-010499-yefxrj30	7	11	of	of	IN
cord-010499-yefxrj30	7	12	HIV‐1	HIV‐1	NNP
cord-010499-yefxrj30	7	13	directs	direct	VBZ
cord-010499-yefxrj30	7	14	analogous	analogous	JJ
cord-010499-yefxrj30	7	15	ribosomal	ribosomal	NN
cord-010499-yefxrj30	7	16	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	7	17	in	in	IN
cord-010499-yefxrj30	7	18	Escherichia	Escherichia	NNP
cord-010499-yefxrj30	7	19	coli	coli	NNS
cord-010499-yefxrj30	7	20	.	.	.
cord-010499-yefxrj30	8	1	Limitation	limitation	NN
cord-010499-yefxrj30	8	2	for	for	IN
cord-010499-yefxrj30	8	3	leucine	leucine	NN
cord-010499-yefxrj30	8	4	,	,	,
cord-010499-yefxrj30	8	5	which	which	WDT
cord-010499-yefxrj30	8	6	is	be	VBZ
cord-010499-yefxrj30	8	7	encoded	encode	VBN
cord-010499-yefxrj30	8	8	precisely	precisely	RB
cord-010499-yefxrj30	8	9	at	at	IN
cord-010499-yefxrj30	8	10	the	the	DT
cord-010499-yefxrj30	8	11	frameshift	frameshift	NN
cord-010499-yefxrj30	8	12	site	site	NN
cord-010499-yefxrj30	8	13	,	,	,
cord-010499-yefxrj30	8	14	dramatically	dramatically	RB
cord-010499-yefxrj30	8	15	increased	increase	VBD
cord-010499-yefxrj30	8	16	the	the	DT
cord-010499-yefxrj30	8	17	frequency	frequency	NN
cord-010499-yefxrj30	8	18	of	of	IN
cord-010499-yefxrj30	8	19	leftward	leftward	JJ
cord-010499-yefxrj30	8	20	frameshifting	frameshifting	NN
cord-010499-yefxrj30	8	21	.	.	.
cord-010499-yefxrj30	9	1	Limitation	limitation	NN
cord-010499-yefxrj30	9	2	for	for	IN
cord-010499-yefxrj30	9	3	phenylaianine	phenylaianine	NN
cord-010499-yefxrj30	9	4	or	or	CC
cord-010499-yefxrj30	9	5	arginine	arginine	NN
cord-010499-yefxrj30	9	6	,	,	,
cord-010499-yefxrj30	9	7	which	which	WDT
cord-010499-yefxrj30	9	8	are	be	VBP
cord-010499-yefxrj30	9	9	encoded	encode	VBN
cord-010499-yefxrj30	9	10	just	just	RB
cord-010499-yefxrj30	9	11	before	before	RB
cord-010499-yefxrj30	9	12	and	and	CC
cord-010499-yefxrj30	9	13	just	just	RB
cord-010499-yefxrj30	9	14	after	after	IN
cord-010499-yefxrj30	9	15	the	the	DT
cord-010499-yefxrj30	9	16	frameshift	frameshift	NN
cord-010499-yefxrj30	9	17	,	,	,
cord-010499-yefxrj30	9	18	did	do	VBD
cord-010499-yefxrj30	9	19	not	not	RB
cord-010499-yefxrj30	9	20	significantly	significantly	RB
cord-010499-yefxrj30	9	21	affect	affect	VB
cord-010499-yefxrj30	9	22	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	9	23	.	.	.
cord-010499-yefxrj30	10	1	Protein	protein	NN
cord-010499-yefxrj30	10	2	sequence	sequence	NN
cord-010499-yefxrj30	10	3	analysis	analysis	NN
cord-010499-yefxrj30	10	4	demonstrated	demonstrate	VBD
cord-010499-yefxrj30	10	5	the	the	DT
cord-010499-yefxrj30	10	6	occurrence	occurrence	NN
cord-010499-yefxrj30	10	7	of	of	IN
cord-010499-yefxrj30	10	8	two	two	CD
cord-010499-yefxrj30	10	9	closeiy	closeiy	NNS
cord-010499-yefxrj30	10	10	related	relate	VBN
cord-010499-yefxrj30	10	11	frameshift	frameshift	NN
cord-010499-yefxrj30	10	12	mechanisms	mechanism	NNS
cord-010499-yefxrj30	10	13	.	.	.
cord-010499-yefxrj30	11	1	In	in	IN
cord-010499-yefxrj30	11	2	the	the	DT
cord-010499-yefxrj30	11	3	first	first	JJ
cord-010499-yefxrj30	11	4	,	,	,
cord-010499-yefxrj30	11	5	ribosomes	ribosome	NNS
cord-010499-yefxrj30	11	6	appear	appear	VBP
cord-010499-yefxrj30	11	7	to	to	TO
cord-010499-yefxrj30	11	8	bind	bind	VB
cord-010499-yefxrj30	11	9	leucyl‐tRNA	leucyl‐tRNA	NNS
cord-010499-yefxrj30	11	10	at	at	IN
cord-010499-yefxrj30	11	11	the	the	DT
cord-010499-yefxrj30	11	12	frameshift	frameshift	NN
cord-010499-yefxrj30	11	13	site	site	NN
cord-010499-yefxrj30	11	14	and	and	CC
cord-010499-yefxrj30	11	15	then	then	RB
cord-010499-yefxrj30	11	16	slip	slip	VB
cord-010499-yefxrj30	11	17	leftward	leftward	RB
cord-010499-yefxrj30	11	18	.	.	.
cord-010499-yefxrj30	12	1	This	this	DT
cord-010499-yefxrj30	12	2	is	be	VBZ
cord-010499-yefxrj30	12	3	the	the	DT
cord-010499-yefxrj30	12	4	'	'	``
cord-010499-yefxrj30	12	5	simultaneous	simultaneous	JJ
cord-010499-yefxrj30	12	6	slippage’mechanism	slippage’mechanism	NN
cord-010499-yefxrj30	12	7	.	.	.
cord-010499-yefxrj30	13	1	In	in	IN
cord-010499-yefxrj30	13	2	the	the	DT
cord-010499-yefxrj30	13	3	second	second	JJ
cord-010499-yefxrj30	13	4	,	,	,
cord-010499-yefxrj30	13	5	ribosomes	ribosome	NNS
cord-010499-yefxrj30	13	6	appear	appear	VBP
cord-010499-yefxrj30	13	7	to	to	TO
cord-010499-yefxrj30	13	8	slip	slip	VB
cord-010499-yefxrj30	13	9	before	before	IN
cord-010499-yefxrj30	13	10	binding	bind	VBG
cord-010499-yefxrj30	13	11	amlnoacyl‐tRNA	amlnoacyl‐tRNA	''
cord-010499-yefxrj30	13	12	,	,	,
cord-010499-yefxrj30	13	13	and	and	CC
cord-010499-yefxrj30	13	14	then	then	RB
cord-010499-yefxrj30	13	15	bind	bind	VB
cord-010499-yefxrj30	13	16	phenylaianyl‐tRNA	phenylaianyl‐tRNA	NNS
cord-010499-yefxrj30	13	17	,	,	,
cord-010499-yefxrj30	13	18	which	which	WDT
cord-010499-yefxrj30	13	19	is	be	VBZ
cord-010499-yefxrj30	13	20	encoded	encode	VBN
cord-010499-yefxrj30	13	21	in	in	IN
cord-010499-yefxrj30	13	22	the	the	DT
cord-010499-yefxrj30	13	23	left‐shifted	left‐shifted	JJ
cord-010499-yefxrj30	13	24	reading	reading	NN
cord-010499-yefxrj30	13	25	frame	frame	NN
cord-010499-yefxrj30	13	26	.	.	.
cord-010499-yefxrj30	14	1	This	this	DT
cord-010499-yefxrj30	14	2	mechanism	mechanism	NN
cord-010499-yefxrj30	14	3	is	be	VBZ
cord-010499-yefxrj30	14	4	identicai	identicai	NN
cord-010499-yefxrj30	14	5	to	to	IN
cord-010499-yefxrj30	14	6	the‘overlapping	the‘overlapping	IN
cord-010499-yefxrj30	14	7	reading’we	reading’we	NNP
cord-010499-yefxrj30	14	8	have	have	VBP
cord-010499-yefxrj30	14	9	demonstrated	demonstrate	VBN
cord-010499-yefxrj30	14	10	at	at	IN
cord-010499-yefxrj30	14	11	other	other	JJ
cord-010499-yefxrj30	14	12	bacterial	bacterial	JJ
cord-010499-yefxrj30	14	13	frameshift	frameshift	NN
cord-010499-yefxrj30	14	14	sites	site	NNS
cord-010499-yefxrj30	14	15	.	.	.
cord-010499-yefxrj30	15	1	The	the	DT
cord-010499-yefxrj30	15	2	HIV‐1	HIV‐1	NNP
cord-010499-yefxrj30	15	3	sequence	sequence	NN
cord-010499-yefxrj30	15	4	is	be	VBZ
cord-010499-yefxrj30	15	5	prone	prone	JJ
cord-010499-yefxrj30	15	6	to	to	IN
cord-010499-yefxrj30	15	7	frame‐shifting	frame‐shifte	VBG
cord-010499-yefxrj30	15	8	by	by	IN
cord-010499-yefxrj30	15	9	both	both	DT
cord-010499-yefxrj30	15	10	mechanisms	mechanism	NNS
cord-010499-yefxrj30	15	11	in	in	IN
cord-010499-yefxrj30	15	12	E.	E.	NNP
cord-010499-yefxrj30	15	13	coli	coli	NNS
cord-010499-yefxrj30	15	14	.	.	.
cord-010499-yefxrj30	16	1	Ribosomes	Ribosomes	NNP
cord-010499-yefxrj30	16	2	normaiiy	normaiiy	NNP
cord-010499-yefxrj30	16	3	maintain	maintain	VBP
cord-010499-yefxrj30	16	4	a	a	DT
cord-010499-yefxrj30	16	5	constant	constant	JJ
cord-010499-yefxrj30	16	6	reading	reading	NN
cord-010499-yefxrj30	16	7	frame	frame	NN
cord-010499-yefxrj30	16	8	from	from	IN
cord-010499-yefxrj30	16	9	AUG	AUG	NNP
cord-010499-yefxrj30	16	10	to	to	IN
cord-010499-yefxrj30	16	11	the	the	DT
cord-010499-yefxrj30	16	12	finish	finish	NN
cord-010499-yefxrj30	16	13	,	,	,
cord-010499-yefxrj30	16	14	but	but	CC
cord-010499-yefxrj30	16	15	they	-PRON-	PRP
cord-010499-yefxrj30	16	16	are	be	VBP
cord-010499-yefxrj30	16	17	capabie	capabie	NNP
cord-010499-yefxrj30	16	18	of	of	IN
cord-010499-yefxrj30	16	19	slipping	slip	VBG
cord-010499-yefxrj30	16	20	into	into	IN
cord-010499-yefxrj30	16	21	an	an	DT
cord-010499-yefxrj30	16	22	alternative	alternative	JJ
cord-010499-yefxrj30	16	23	reading	reading	NN
cord-010499-yefxrj30	16	24	frame	frame	NN
cord-010499-yefxrj30	16	25	at	at	IN
cord-010499-yefxrj30	16	26	an	an	DT
cord-010499-yefxrj30	16	27	average	average	JJ
cord-010499-yefxrj30	16	28	frequency	frequency	NN
cord-010499-yefxrj30	16	29	of	of	IN
cord-010499-yefxrj30	16	30	the	the	DT
cord-010499-yefxrj30	16	31	order	order	NN
cord-010499-yefxrj30	16	32	of	of	IN
cord-010499-yefxrj30	16	33	10	10	CD
cord-010499-yefxrj30	16	34	"	"	''
cord-010499-yefxrj30	16	35	(	(	-LRB-
cord-010499-yefxrj30	16	36	Atkins	Atkins	NNP
cord-010499-yefxrj30	16	37	etai	etai	NNP
cord-010499-yefxrj30	16	38	,	,	,
cord-010499-yefxrj30	16	39	1972	1972	CD
cord-010499-yefxrj30	16	40	;	;	:
cord-010499-yefxrj30	16	41	J.	J.	NNP
cord-010499-yefxrj30	16	42	A.	A.	NNP
cord-010499-yefxrj30	16	43	Gallant	Gallant	NNP
cord-010499-yefxrj30	16	44	etai	etai	NNP
cord-010499-yefxrj30	16	45	,	,	,
cord-010499-yefxrj30	16	46	unpubiished	unpubiished	JJ
cord-010499-yefxrj30	16	47	)	)	-RRB-
cord-010499-yefxrj30	16	48	.	.	.
cord-010499-yefxrj30	17	1	In	in	IN
cord-010499-yefxrj30	17	2	certain	certain	JJ
cord-010499-yefxrj30	17	3	special	special	JJ
cord-010499-yefxrj30	17	4	cases	case	NNS
cord-010499-yefxrj30	17	5	,	,	,
cord-010499-yefxrj30	17	6	much	much	RB
cord-010499-yefxrj30	17	7	higher	high	JJR
cord-010499-yefxrj30	17	8	frequencies	frequency	NNS
cord-010499-yefxrj30	17	9	of	of	IN
cord-010499-yefxrj30	17	10	ribosome	ribosome	NN
cord-010499-yefxrj30	17	11	frameshifting	frameshifting	NN
cord-010499-yefxrj30	17	12	occur	occur	VBP
cord-010499-yefxrj30	17	13	.	.	.
cord-010499-yefxrj30	18	1	These	these	DT
cord-010499-yefxrj30	18	2	cases	case	NNS
cord-010499-yefxrj30	18	3	include	include	VBP
cord-010499-yefxrj30	18	4	production	production	NN
cord-010499-yefxrj30	18	5	of	of	IN
cord-010499-yefxrj30	18	6	polypeptide	polypeptide	NN
cord-010499-yefxrj30	18	7	release	release	NN
cord-010499-yefxrj30	18	8	factor	factor	NN
cord-010499-yefxrj30	18	9	2	2	CD
cord-010499-yefxrj30	18	10	of	of	IN
cord-010499-yefxrj30	18	11	Escherichia	Escherichia	NNP
cord-010499-yefxrj30	18	12	coli	coli	NNS
cord-010499-yefxrj30	18	13	,	,	,
cord-010499-yefxrj30	18	14	which	which	WDT
cord-010499-yefxrj30	18	15	depends	depend	VBZ
cord-010499-yefxrj30	18	16	upon	upon	IN
cord-010499-yefxrj30	18	17	a	a	DT
cord-010499-yefxrj30	18	18	rightward	rightward	JJ
cord-010499-yefxrj30	18	19	frameshift	frameshift	NN
cord-010499-yefxrj30	18	20	within	within	IN
cord-010499-yefxrj30	18	21	the	the	DT
cord-010499-yefxrj30	18	22	coding	coding	NN
cord-010499-yefxrj30	18	23	sequence	sequence	NN
cord-010499-yefxrj30	19	1	(	(	-LRB-
cord-010499-yefxrj30	19	2	Craigen	Craigen	NNP
cord-010499-yefxrj30	19	3	et	et	NNP
cord-010499-yefxrj30	19	4	at	at	IN
cord-010499-yefxrj30	19	5	..	..	CD
cord-010499-yefxrj30	19	6	1985	1985	CD
cord-010499-yefxrj30	19	7	;	;	:
cord-010499-yefxrj30	19	8	Craigen	Craigen	NNP
cord-010499-yefxrj30	19	9	and	and	CC
cord-010499-yefxrj30	19	10	Caskey	Caskey	NNP
cord-010499-yefxrj30	19	11	,	,	,
cord-010499-yefxrj30	19	12	1987	1987	CD
cord-010499-yefxrj30	19	13	;	;	:
cord-010499-yefxrj30	19	14	Weiss	Weiss	NNP
cord-010499-yefxrj30	19	15	et	et	NNP
cord-010499-yefxrj30	19	16	ai	ai	NNP
cord-010499-yefxrj30	19	17	,	,	,
cord-010499-yefxrj30	19	18	1987	1987	CD
cord-010499-yefxrj30	19	19	;	;	:
cord-010499-yefxrj30	19	20	Curran	Curran	NNP
cord-010499-yefxrj30	19	21	and	and	CC
cord-010499-yefxrj30	19	22	Yarus	Yarus	NNP
cord-010499-yefxrj30	19	23	,	,	,
cord-010499-yefxrj30	19	24	1988	1988	CD
cord-010499-yefxrj30	19	25	)	)	-RRB-
cord-010499-yefxrj30	19	26	;	;	:
cord-010499-yefxrj30	19	27	translation	translation	NN
cord-010499-yefxrj30	19	28	of	of	IN
cord-010499-yefxrj30	19	29	the	the	DT
cord-010499-yefxrj30	19	30	reverse	reverse	JJ
cord-010499-yefxrj30	19	31	transcriptase	transcriptase	NN
cord-010499-yefxrj30	19	32	of	of	IN
cord-010499-yefxrj30	19	33	the	the	DT
cord-010499-yefxrj30	19	34	yeast	yeast	NN
cord-010499-yefxrj30	19	35	Ty	Ty	NNP
cord-010499-yefxrj30	19	36	element	element	NN
cord-010499-yefxrj30	19	37	,	,	,
cord-010499-yefxrj30	19	38	which	which	WDT
cord-010499-yefxrj30	19	39	also	also	RB
cord-010499-yefxrj30	19	40	depends	depend	VBZ
cord-010499-yefxrj30	19	41	upon	upon	IN
cord-010499-yefxrj30	19	42	a	a	DT
cord-010499-yefxrj30	19	43	rightward	rightward	JJ
cord-010499-yefxrj30	19	44	frameshift	frameshift	NN
cord-010499-yefxrj30	19	45	(	(	-LRB-
cord-010499-yefxrj30	19	46	Clare	Clare	NNP
cord-010499-yefxrj30	19	47	ef	ef	NNP
cord-010499-yefxrj30	19	48	ai	ai	NNP
cord-010499-yefxrj30	19	49	,	,	,
cord-010499-yefxrj30	19	50	1988	1988	CD
cord-010499-yefxrj30	19	51	)	)	-RRB-
cord-010499-yefxrj30	19	52	;	;	:
cord-010499-yefxrj30	19	53	and	and	CC
cord-010499-yefxrj30	19	54	translation	translation	NN
cord-010499-yefxrj30	19	55	of	of	IN
cord-010499-yefxrj30	19	56	the	the	DT
cord-010499-yefxrj30	19	57	RNA	RNA	NNP
cord-010499-yefxrj30	19	58	of	of	IN
cord-010499-yefxrj30	19	59	severai	severai	NNP
cord-010499-yefxrj30	19	60	retroviruses	retrovirus	NNS
cord-010499-yefxrj30	19	61	,	,	,
cord-010499-yefxrj30	19	62	which	which	WDT
cord-010499-yefxrj30	19	63	express	express	VBP
cord-010499-yefxrj30	19	64	gag	gag	NN
cord-010499-yefxrj30	19	65	-	-	HYPH
cord-010499-yefxrj30	19	66	pol	pol	NN
cord-010499-yefxrj30	19	67	and	and	CC
cord-010499-yefxrj30	19	68	gag	gag	NN
cord-010499-yefxrj30	19	69	-	-	HYPH
cord-010499-yefxrj30	19	70	pro	pro	JJ
cord-010499-yefxrj30	19	71	-	-	JJ
cord-010499-yefxrj30	19	72	pol	pol	JJ
cord-010499-yefxrj30	19	73	polyproteins	polyprotein	NNS
cord-010499-yefxrj30	19	74	by	by	IN
cord-010499-yefxrj30	19	75	means	mean	NNS
cord-010499-yefxrj30	19	76	of	of	IN
cord-010499-yefxrj30	19	77	leftward	leftward	NNP
cord-010499-yefxrj30	19	78	frameshifts	frameshifts	NNP
cord-010499-yefxrj30	19	79	(	(	-LRB-
cord-010499-yefxrj30	19	80	reviewed	review	VBN
cord-010499-yefxrj30	19	81	by	by	IN
cord-010499-yefxrj30	19	82	Hatfield	Hatfield	NNP
cord-010499-yefxrj30	19	83	and	and	CC
cord-010499-yefxrj30	19	84	Oroszlan	Oroszlan	NNP
cord-010499-yefxrj30	19	85	,	,	,
cord-010499-yefxrj30	19	86	1990	1990	CD
cord-010499-yefxrj30	19	87	;	;	:
cord-010499-yefxrj30	19	88	Cattaneo	Cattaneo	NNP
cord-010499-yefxrj30	19	89	,	,	,
cord-010499-yefxrj30	19	90	1989	1989	CD
cord-010499-yefxrj30	19	91	)	)	-RRB-
cord-010499-yefxrj30	19	92	.	.	.
cord-010499-yefxrj30	20	1	Ribosomal	Ribosomal	NNP
cord-010499-yefxrj30	20	2	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	20	3	in	in	IN
cord-010499-yefxrj30	20	4	both	both	CC
cord-010499-yefxrj30	20	5	rightward	rightward	JJ
cord-010499-yefxrj30	20	6	and	and	CC
cord-010499-yefxrj30	20	7	leftward	leftward	JJ
cord-010499-yefxrj30	20	8	directions	direction	NNS
cord-010499-yefxrj30	20	9	has	have	VBZ
cord-010499-yefxrj30	20	10	also	also	RB
cord-010499-yefxrj30	20	11	been	be	VBN
cord-010499-yefxrj30	20	12	shown	show	VBN
cord-010499-yefxrj30	20	13	to	to	TO
cord-010499-yefxrj30	20	14	occur	occur	VB
cord-010499-yefxrj30	20	15	at	at	IN
cord-010499-yefxrj30	20	16	certain	certain	JJ
cord-010499-yefxrj30	20	17	'	'	``
cord-010499-yefxrj30	20	18	hungry	hungry	JJ
cord-010499-yefxrj30	20	19	'	'	''
cord-010499-yefxrj30	20	20	codons	codon	NNS
cord-010499-yefxrj30	20	21	whose	whose	WP$
cord-010499-yefxrj30	20	22	cognate	cognate	JJ
cord-010499-yefxrj30	20	23	aminoacyi	aminoacyi	RB
cord-010499-yefxrj30	20	24	-	-	HYPH
cord-010499-yefxrj30	20	25	tRNAs	trna	NNS
cord-010499-yefxrj30	20	26	are	be	VBP
cord-010499-yefxrj30	20	27	in	in	IN
cord-010499-yefxrj30	20	28	short	short	JJ
cord-010499-yefxrj30	20	29	supply	supply	NN
cord-010499-yefxrj30	20	30	(	(	-LRB-
cord-010499-yefxrj30	20	31	Gallant	Gallant	NNP
cord-010499-yefxrj30	20	32	and	and	CC
cord-010499-yefxrj30	20	33	Foley	Foley	NNP
cord-010499-yefxrj30	20	34	,	,	,
cord-010499-yefxrj30	20	35	1980	1980	CD
cord-010499-yefxrj30	20	36	;	;	:
cord-010499-yefxrj30	20	37	Weiss	Weiss	NNP
cord-010499-yefxrj30	20	38	and	and	CC
cord-010499-yefxrj30	20	39	Gailant	Gailant	NNP
cord-010499-yefxrj30	20	40	,	,	,
cord-010499-yefxrj30	20	41	1983	1983	CD
cord-010499-yefxrj30	20	42	;	;	:
cord-010499-yefxrj30	20	43	1986	1986	CD
cord-010499-yefxrj30	20	44	;	;	:
cord-010499-yefxrj30	20	45	Gallant	Gallant	NNP
cord-010499-yefxrj30	20	46	et	et	NNP
cord-010499-yefxrj30	20	47	ai	ai	NNP
cord-010499-yefxrj30	20	48	,	,	,
cord-010499-yefxrj30	20	49	1985	1985	CD
cord-010499-yefxrj30	20	50	;	;	:
cord-010499-yefxrj30	20	51	Kurland	Kurland	NNP
cord-010499-yefxrj30	20	52	and	and	CC
cord-010499-yefxrj30	20	53	Gallant	Gallant	NNP
cord-010499-yefxrj30	20	54	,	,	,
cord-010499-yefxrj30	20	55	1986	1986	CD
cord-010499-yefxrj30	20	56	)	)	-RRB-
cord-010499-yefxrj30	20	57	.	.	.
cord-010499-yefxrj30	21	1	Not	not	RB
cord-010499-yefxrj30	21	2	all	all	DT
cord-010499-yefxrj30	21	3	hungry	hungry	JJ
cord-010499-yefxrj30	21	4	codons	codon	NNS
cord-010499-yefxrj30	21	5	are	be	VBP
cord-010499-yefxrj30	21	6	equally	equally	RB
cord-010499-yefxrj30	21	7	prone	prone	JJ
cord-010499-yefxrj30	21	8	to	to	TO
cord-010499-yefxrj30	21	9	shift	shift	VB
cord-010499-yefxrj30	21	10	:	:	:
cord-010499-yefxrj30	21	11	in	in	IN
cord-010499-yefxrj30	21	12	a	a	DT
cord-010499-yefxrj30	21	13	survey	survey	NN
cord-010499-yefxrj30	21	14	of	of	IN
cord-010499-yefxrj30	21	15	21	21	CD
cord-010499-yefxrj30	21	16	frameshift	frameshift	NN
cord-010499-yefxrj30	21	17	mutations	mutation	NNS
cord-010499-yefxrj30	21	18	of	of	IN
cord-010499-yefxrj30	21	19	the	the	DT
cord-010499-yefxrj30	21	20	rllB	rllB	NNP
cord-010499-yefxrj30	21	21	gene	gene	NN
cord-010499-yefxrj30	21	22	of	of	IN
cord-010499-yefxrj30	21	23	phage	phage	NN
cord-010499-yefxrj30	21	24	T4	T4	NNP
cord-010499-yefxrj30	21	25	,	,	,
cord-010499-yefxrj30	21	26	Weiss	Weiss	NNP
cord-010499-yefxrj30	21	27	and	and	CC
cord-010499-yefxrj30	21	28	Gallant	Gallant	NNP
cord-010499-yefxrj30	21	29	(	(	-LRB-
cord-010499-yefxrj30	21	30	1986	1986	CD
cord-010499-yefxrj30	21	31	)	)	-RRB-
cord-010499-yefxrj30	21	32	found	find	VBD
cord-010499-yefxrj30	21	33	that	that	IN
cord-010499-yefxrj30	21	34	oniy	oniy	RB
cord-010499-yefxrj30	21	35	a	a	DT
cord-010499-yefxrj30	21	36	minority	minority	NN
cord-010499-yefxrj30	21	37	were	be	VBD
cord-010499-yefxrj30	21	38	phenotypicaily	phenotypicaily	RB
cord-010499-yefxrj30	21	39	suppressible	suppressible	JJ
cord-010499-yefxrj30	21	40	when	when	WRB
cord-010499-yefxrj30	21	41	challenged	challenge	VBN
cord-010499-yefxrj30	21	42	by	by	IN
cord-010499-yefxrj30	21	43	limitation	limitation	NN
cord-010499-yefxrj30	21	44	for	for	IN
cord-010499-yefxrj30	21	45	any	any	DT
cord-010499-yefxrj30	21	46	of	of	IN
cord-010499-yefxrj30	21	47	several	several	JJ
cord-010499-yefxrj30	21	48	aminoacyl	aminoacyl	NNS
cord-010499-yefxrj30	21	49	-	-	HYPH
cord-010499-yefxrj30	21	50	tRNAs	trna	NNS
cord-010499-yefxrj30	21	51	.	.	.
cord-010499-yefxrj30	22	1	The	the	DT
cord-010499-yefxrj30	22	2	context	context	NN
cord-010499-yefxrj30	22	3	njies	njie	NNS
cord-010499-yefxrj30	22	4	governing	govern	VBG
cord-010499-yefxrj30	22	5	ribosome	ribosome	NN
cord-010499-yefxrj30	22	6	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	22	7	at	at	IN
cord-010499-yefxrj30	22	8	hungry	hungry	JJ
cord-010499-yefxrj30	22	9	sites	site	NNS
cord-010499-yefxrj30	22	10	are	be	VBP
cord-010499-yefxrj30	22	11	under	under	IN
cord-010499-yefxrj30	22	12	investigation	investigation	NN
cord-010499-yefxrj30	22	13	,	,	,
cord-010499-yefxrj30	22	14	and	and	CC
cord-010499-yefxrj30	22	15	have	have	VBP
cord-010499-yefxrj30	22	16	been	be	VBN
cord-010499-yefxrj30	22	17	defined	define	VBN
cord-010499-yefxrj30	22	18	in	in	IN
cord-010499-yefxrj30	22	19	a	a	DT
cord-010499-yefxrj30	22	20	few	few	JJ
cord-010499-yefxrj30	22	21	cases	case	NNS
cord-010499-yefxrj30	23	1	(	(	-LRB-
cord-010499-yefxrj30	23	2	Weiss	Weiss	NNP
cord-010499-yefxrj30	23	3	et	et	NNP
cord-010499-yefxrj30	23	4	al	al	NNP
cord-010499-yefxrj30	23	5	.	.	.
cord-010499-yefxrj30	24	1	,	,	,
cord-010499-yefxrj30	24	2	1988	1988	CD
cord-010499-yefxrj30	24	3	;	;	:
cord-010499-yefxrj30	24	4	Gallant	Gallant	NNP
cord-010499-yefxrj30	24	5	and	and	CC
cord-010499-yefxrj30	24	6	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	24	7	,	,	,
cord-010499-yefxrj30	24	8	1992	1992	CD
cord-010499-yefxrj30	24	9	;	;	:
cord-010499-yefxrj30	24	10	Peter	Peter	NNP
cord-010499-yefxrj30	24	11	et	et	NNP
cord-010499-yefxrj30	24	12	ai	ai	NNP
cord-010499-yefxrj30	24	13	.	.	.
cord-010499-yefxrj30	25	1	1992	1992	CD
cord-010499-yefxrj30	25	2	;	;	:
cord-010499-yefxrj30	25	3	Koior	Koior	NNP
cord-010499-yefxrj30	25	4	ef	ef	NNP
cord-010499-yefxrj30	25	5	a/.	a/.	NNP
cord-010499-yefxrj30	25	6	,	,	,
cord-010499-yefxrj30	25	7	1993	1993	CD
cord-010499-yefxrj30	25	8	;	;	:
cord-010499-yefxrj30	26	1	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	26	2	and	and	CC
cord-010499-yefxrj30	26	3	Gallant	Gallant	NNP
cord-010499-yefxrj30	26	4	,	,	,
cord-010499-yefxrj30	26	5	1993	1993	CD
cord-010499-yefxrj30	26	6	)	)	-RRB-
cord-010499-yefxrj30	26	7	.	.	.
cord-010499-yefxrj30	27	1	So	so	RB
cord-010499-yefxrj30	27	2	far	far	RB
cord-010499-yefxrj30	27	3	these	these	DT
cord-010499-yefxrj30	27	4	sequences	sequence	NNS
cord-010499-yefxrj30	27	5	do	do	VBP
cord-010499-yefxrj30	27	6	not	not	RB
cord-010499-yefxrj30	27	7	resembie	resembie	VB
cord-010499-yefxrj30	27	8	any	any	DT
cord-010499-yefxrj30	27	9	of	of	IN
cord-010499-yefxrj30	27	10	the	the	DT
cord-010499-yefxrj30	27	11	naturally	naturally	RB
cord-010499-yefxrj30	27	12	occurring	occur	VBG
cord-010499-yefxrj30	27	13	shifty	shifty	JJ
cord-010499-yefxrj30	27	14	sites	site	NNS
cord-010499-yefxrj30	27	15	summarized	summarize	VBN
cord-010499-yefxrj30	27	16	in	in	IN
cord-010499-yefxrj30	27	17	the	the	DT
cord-010499-yefxrj30	27	18	first	first	JJ
cord-010499-yefxrj30	27	19	paragraph	paragraph	NN
cord-010499-yefxrj30	27	20	above	above	RB
cord-010499-yefxrj30	27	21	,	,	,
cord-010499-yefxrj30	27	22	in	in	IN
cord-010499-yefxrj30	27	23	order	order	NN
cord-010499-yefxrj30	27	24	to	to	TO
cord-010499-yefxrj30	27	25	find	find	VB
cord-010499-yefxrj30	27	26	out	out	RP
cord-010499-yefxrj30	27	27	whether	whether	IN
cord-010499-yefxrj30	27	28	these	these	DT
cord-010499-yefxrj30	27	29	two	two	CD
cord-010499-yefxrj30	27	30	categories	category	NNS
cord-010499-yefxrj30	27	31	of	of	IN
cord-010499-yefxrj30	27	32	ribosome	ribosome	NN
cord-010499-yefxrj30	27	33	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	27	34	are	be	VBP
cord-010499-yefxrj30	27	35	mechanisticaliy	mechanisticaliy	JJ
cord-010499-yefxrj30	27	36	reiated	reiate	VBN
cord-010499-yefxrj30	27	37	,	,	,
cord-010499-yefxrj30	27	38	we	-PRON-	PRP
cord-010499-yefxrj30	27	39	have	have	VBP
cord-010499-yefxrj30	27	40	tested	test	VBN
cord-010499-yefxrj30	27	41	the	the	DT
cord-010499-yefxrj30	27	42	susceptibility	susceptibility	NN
cord-010499-yefxrj30	27	43	of	of	IN
cord-010499-yefxrj30	27	44	a	a	DT
cord-010499-yefxrj30	27	45	well	well	RB
cord-010499-yefxrj30	27	46	-	-	HYPH
cord-010499-yefxrj30	27	47	studied	study	VBN
cord-010499-yefxrj30	27	48	retroviral	retroviral	JJ
cord-010499-yefxrj30	27	49	frameshift	frameshift	NN
cord-010499-yefxrj30	27	50	site	site	NN
cord-010499-yefxrj30	27	51	to	to	IN
cord-010499-yefxrj30	27	52	manipulation	manipulation	NN
cord-010499-yefxrj30	27	53	by	by	IN
cord-010499-yefxrj30	27	54	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	27	55	-	-	HYPH
cord-010499-yefxrj30	27	56	tRNA	trna	NN
cord-010499-yefxrj30	27	57	limitation	limitation	NN
cord-010499-yefxrj30	27	58	in	in	IN
cord-010499-yefxrj30	27	59	E.	E.	NNP
cord-010499-yefxrj30	27	60	coli	coli	NNS
cord-010499-yefxrj30	28	1	We	-PRON-	PRP
cord-010499-yefxrj30	28	2	have	have	VBP
cord-010499-yefxrj30	28	3	directed	direct	VBN
cord-010499-yefxrj30	28	4	our	-PRON-	PRP$
cord-010499-yefxrj30	28	5	analysis	analysis	NN
cord-010499-yefxrj30	28	6	to	to	IN
cord-010499-yefxrj30	28	7	the	the	DT
cord-010499-yefxrj30	28	8	shifty	shifty	JJ
cord-010499-yefxrj30	28	9	site	site	NN
cord-010499-yefxrj30	28	10	at	at	IN
cord-010499-yefxrj30	28	11	the	the	DT
cord-010499-yefxrj30	28	12	gag	gag	NN
cord-010499-yefxrj30	28	13	-	-	HYPH
cord-010499-yefxrj30	28	14	pol	pol	NN
cord-010499-yefxrj30	28	15	junction	junction	NN
cord-010499-yefxrj30	28	16	of	of	IN
cord-010499-yefxrj30	28	17	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	28	18	both	both	DT
cord-010499-yefxrj30	28	19	because	because	IN
cord-010499-yefxrj30	28	20	of	of	IN
cord-010499-yefxrj30	28	21	its	-PRON-	PRP$
cord-010499-yefxrj30	28	22	clinical	clinical	JJ
cord-010499-yefxrj30	28	23	interest	interest	NN
cord-010499-yefxrj30	28	24	,	,	,
cord-010499-yefxrj30	28	25	and	and	CC
cord-010499-yefxrj30	28	26	because	because	IN
cord-010499-yefxrj30	28	27	certain	certain	JJ
cord-010499-yefxrj30	28	28	features	feature	NNS
cord-010499-yefxrj30	28	29	render	render	VBP
cord-010499-yefxrj30	28	30	it	-PRON-	PRP
cord-010499-yefxrj30	28	31	convenient	convenient	JJ
cord-010499-yefxrj30	28	32	for	for	IN
cord-010499-yefxrj30	28	33	analysis	analysis	NN
cord-010499-yefxrj30	28	34	.	.	.
cord-010499-yefxrj30	29	1	In	in	IN
cord-010499-yefxrj30	29	2	some	some	DT
cord-010499-yefxrj30	29	3	viral	viral	JJ
cord-010499-yefxrj30	29	4	systems	system	NNS
cord-010499-yefxrj30	29	5	,	,	,
cord-010499-yefxrj30	29	6	baroque	baroque	JJ
cord-010499-yefxrj30	29	7	secondary	secondary	JJ
cord-010499-yefxrj30	29	8	structures	structure	NNS
cord-010499-yefxrj30	29	9	in	in	IN
cord-010499-yefxrj30	29	10	the	the	DT
cord-010499-yefxrj30	29	11	mRNA	mRNA	NNP
cord-010499-yefxrj30	29	12	downstream	downstream	NN
cord-010499-yefxrj30	29	13	of	of	IN
cord-010499-yefxrj30	29	14	the	the	DT
cord-010499-yefxrj30	29	15	frameshift	frameshift	NN
cord-010499-yefxrj30	29	16	site	site	NN
cord-010499-yefxrj30	29	17	are	be	VBP
cord-010499-yefxrj30	29	18	required	require	VBN
cord-010499-yefxrj30	29	19	to	to	TO
cord-010499-yefxrj30	29	20	augment	augment	VB
cord-010499-yefxrj30	29	21	frameshifting	frameshifting	JJ
cord-010499-yefxrj30	29	22	levels	level	NNS
cord-010499-yefxrj30	29	23	(	(	-LRB-
cord-010499-yefxrj30	29	24	Jacks	Jacks	NNP
cord-010499-yefxrj30	29	25	et	et	NNP
cord-010499-yefxrj30	29	26	ai	ai	NN
cord-010499-yefxrj30	29	27	,	,	,
cord-010499-yefxrj30	29	28	1988b	1988b	CD
cord-010499-yefxrj30	29	29	;	;	:
cord-010499-yefxrj30	29	30	Brierley	Brierley	NNP
cord-010499-yefxrj30	29	31	et	et	NNP
cord-010499-yefxrj30	29	32	ai	ai	NNP
cord-010499-yefxrj30	29	33	,	,	,
cord-010499-yefxrj30	29	34	1989	1989	CD
cord-010499-yefxrj30	29	35	)	)	-RRB-
cord-010499-yefxrj30	29	36	.	.	.
cord-010499-yefxrj30	30	1	In	in	IN
cord-010499-yefxrj30	30	2	the	the	DT
cord-010499-yefxrj30	30	3	case	case	NN
cord-010499-yefxrj30	30	4	of	of	IN
cord-010499-yefxrj30	30	5	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	30	6	,	,	,
cord-010499-yefxrj30	30	7	however	however	RB
cord-010499-yefxrj30	30	8	,	,	,
cord-010499-yefxrj30	30	9	although	although	IN
cord-010499-yefxrj30	30	10	a	a	DT
cord-010499-yefxrj30	30	11	stem	stem	NN
cord-010499-yefxrj30	30	12	-	-	HYPH
cord-010499-yefxrj30	30	13	loop	loop	NN
cord-010499-yefxrj30	30	14	structure	structure	NN
cord-010499-yefxrj30	30	15	might	may	MD
cord-010499-yefxrj30	30	16	exist	exist	VB
cord-010499-yefxrj30	30	17	downstream	downstream	RB
cord-010499-yefxrj30	30	18	of	of	IN
cord-010499-yefxrj30	30	19	the	the	DT
cord-010499-yefxrj30	30	20	frameshift	frameshift	NN
cord-010499-yefxrj30	30	21	site	site	NN
cord-010499-yefxrj30	31	1	(	(	-LRB-
cord-010499-yefxrj30	31	2	Jacks	Jacks	NNP
cord-010499-yefxrj30	31	3	et	et	NNP
cord-010499-yefxrj30	31	4	ai	ai	NN
cord-010499-yefxrj30	31	5	,	,	,
cord-010499-yefxrj30	31	6	1988a	1988a	CD
cord-010499-yefxrj30	31	7	)	)	-RRB-
cord-010499-yefxrj30	31	8	,	,	,
cord-010499-yefxrj30	32	1	direct	direct	JJ
cord-010499-yefxrj30	32	2	modification	modification	NN
cord-010499-yefxrj30	32	3	or	or	CC
cord-010499-yefxrj30	32	4	elimination	elimination	NN
cord-010499-yefxrj30	32	5	of	of	IN
cord-010499-yefxrj30	32	6	the	the	DT
cord-010499-yefxrj30	32	7	stem	stem	NN
cord-010499-yefxrj30	32	8	-	-	HYPH
cord-010499-yefxrj30	32	9	loop	loop	NN
cord-010499-yefxrj30	32	10	sequence	sequence	NN
cord-010499-yefxrj30	32	11	has	have	VBZ
cord-010499-yefxrj30	32	12	little	little	JJ
cord-010499-yefxrj30	32	13	effect	effect	NN
cord-010499-yefxrj30	32	14	on	on	IN
cord-010499-yefxrj30	32	15	the	the	DT
cord-010499-yefxrj30	32	16	rate	rate	NN
cord-010499-yefxrj30	32	17	of	of	IN
cord-010499-yefxrj30	32	18	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	33	1	(	(	-LRB-
cord-010499-yefxrj30	33	2	Madhani	Madhani	NNP
cord-010499-yefxrj30	33	3	et	et	NNP
cord-010499-yefxrj30	33	4	ai	ai	NNP
cord-010499-yefxrj30	33	5	,	,	,
cord-010499-yefxrj30	33	6	1988	1988	CD
cord-010499-yefxrj30	33	7	;	;	:
cord-010499-yefxrj30	33	8	Weiss	Weiss	NNP
cord-010499-yefxrj30	33	9	etai	etai	NNP
cord-010499-yefxrj30	33	10	.	.	.
cord-010499-yefxrj30	33	11	1989	1989	CD
cord-010499-yefxrj30	33	12	)	)	-RRB-
cord-010499-yefxrj30	33	13	.	.	.
cord-010499-yefxrj30	34	1	Moreover	moreover	RB
cord-010499-yefxrj30	34	2	,	,	,
cord-010499-yefxrj30	34	3	Wilson	Wilson	NNP
cord-010499-yefxrj30	34	4	etal	etal	NNP
cord-010499-yefxrj30	34	5	.	.	.
cord-010499-yefxrj30	35	1	(	(	-LRB-
cord-010499-yefxrj30	35	2	1988	1988	CD
cord-010499-yefxrj30	35	3	)	)	-RRB-
cord-010499-yefxrj30	35	4	demonstrated	demonstrate	VBD
cord-010499-yefxrj30	35	5	that	that	IN
cord-010499-yefxrj30	35	6	a	a	DT
cord-010499-yefxrj30	35	7	short	short	JJ
cord-010499-yefxrj30	35	8	(	(	-LRB-
cord-010499-yefxrj30	35	9	21	21	CD
cord-010499-yefxrj30	35	10	nucleotide	nucleotide	NN
cord-010499-yefxrj30	35	11	)	)	-RRB-
cord-010499-yefxrj30	35	12	sequence	sequence	NN
cord-010499-yefxrj30	35	13	of	of	IN
cord-010499-yefxrj30	35	14	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	35	15	without	without	IN
cord-010499-yefxrj30	35	16	the	the	DT
cord-010499-yefxrj30	35	17	stem	stem	NN
cord-010499-yefxrj30	35	18	-	-	HYPH
cord-010499-yefxrj30	35	19	loop	loop	NN
cord-010499-yefxrj30	35	20	was	be	VBD
cord-010499-yefxrj30	35	21	sufficient	sufficient	JJ
cord-010499-yefxrj30	35	22	to	to	TO
cord-010499-yefxrj30	35	23	direct	direct	VB
cord-010499-yefxrj30	35	24	a	a	DT
cord-010499-yefxrj30	35	25	high	high	JJ
cord-010499-yefxrj30	35	26	level	level	NN
cord-010499-yefxrj30	35	27	of	of	IN
cord-010499-yefxrj30	35	28	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	35	29	in	in	IN
cord-010499-yefxrj30	35	30	heterologous	heterologous	NNP
cord-010499-yefxrj30	35	31	in	in	IN
cord-010499-yefxrj30	35	32	vitro	vitro	FW
cord-010499-yefxrj30	35	33	systems	system	NNS
cord-010499-yefxrj30	35	34	.	.	.
cord-010499-yefxrj30	36	1	The	the	DT
cord-010499-yefxrj30	36	2	site	site	NN
cord-010499-yefxrj30	36	3	of	of	IN
cord-010499-yefxrj30	36	4	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	36	5	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	36	6	at	at	IN
cord-010499-yefxrj30	36	7	the	the	DT
cord-010499-yefxrj30	36	8	siippery	siippery	NNP
cord-010499-yefxrj30	36	9	sequence	sequence	NN
cord-010499-yefxrj30	37	1	U	U	NNP
cord-010499-yefxrj30	37	2	-	-	HYPH
cord-010499-yefxrj30	37	3	UUU	UUU	NNP
cord-010499-yefxrj30	37	4	-	-	HYPH
cord-010499-yefxrj30	37	5	UUA	UUA	NNP
cord-010499-yefxrj30	37	6	has	have	VBZ
cord-010499-yefxrj30	37	7	been	be	VBN
cord-010499-yefxrj30	37	8	directly	directly	RB
cord-010499-yefxrj30	37	9	established	establish	VBN
cord-010499-yefxrj30	37	10	by	by	IN
cord-010499-yefxrj30	37	11	amino	amino	NN
cord-010499-yefxrj30	37	12	acid	acid	NN
cord-010499-yefxrj30	37	13	sequencing	sequencing	NN
cord-010499-yefxrj30	37	14	of	of	IN
cord-010499-yefxrj30	37	15	frameshifted	frameshifte	VBN
cord-010499-yefxrj30	37	16	proteins	protein	NNS
cord-010499-yefxrj30	37	17	(	(	-LRB-
cord-010499-yefxrj30	38	1	Jacks	Jacks	NNP
cord-010499-yefxrj30	38	2	et	et	NNP
cord-010499-yefxrj30	38	3	ai	ai	NNP
cord-010499-yefxrj30	38	4	.	.	NNP
cord-010499-yefxrj30	38	5	,	,	,
cord-010499-yefxrj30	38	6	1988b	1988b	CD
cord-010499-yefxrj30	38	7	)	)	-RRB-
cord-010499-yefxrj30	38	8	,	,	,
cord-010499-yefxrj30	38	9	and	and	CC
cord-010499-yefxrj30	39	1	the	the	DT
cord-010499-yefxrj30	39	2	participation	participation	NN
cord-010499-yefxrj30	39	3	of	of	IN
cord-010499-yefxrj30	39	4	certain	certain	JJ
cord-010499-yefxrj30	39	5	aminoacyl	aminoacyl	NNS
cord-010499-yefxrj30	39	6	-	-	HYPH
cord-010499-yefxrj30	39	7	tRNAs	tRNAs	NNP
cord-010499-yefxrj30	39	8	has	have	VBZ
cord-010499-yefxrj30	39	9	been	be	VBN
cord-010499-yefxrj30	39	10	clearly	clearly	RB
cord-010499-yefxrj30	39	11	implicated	implicate	VBN
cord-010499-yefxrj30	39	12	by	by	IN
cord-010499-yefxrj30	39	13	mutagenesis	mutagenesis	NN
cord-010499-yefxrj30	39	14	of	of	IN
cord-010499-yefxrj30	39	15	the	the	DT
cord-010499-yefxrj30	39	16	monotonous	monotonous	JJ
cord-010499-yefxrj30	39	17	tract	tract	NN
cord-010499-yefxrj30	39	18	of	of	IN
cord-010499-yefxrj30	39	19	uridines	uridine	NNS
cord-010499-yefxrj30	39	20	(	(	-LRB-
cord-010499-yefxrj30	39	21	Jacks	Jacks	NNP
cord-010499-yefxrj30	39	22	et	et	NNP
cord-010499-yefxrj30	39	23	ai	ai	NN
cord-010499-yefxrj30	39	24	,	,	,
cord-010499-yefxrj30	39	25	1988b	1988b	CD
cord-010499-yefxrj30	39	26	;	;	:
cord-010499-yefxrj30	39	27	Wiison	Wiison	NNP
cord-010499-yefxrj30	39	28	et	et	NNP
cord-010499-yefxrj30	39	29	ai	ai	NNP
cord-010499-yefxrj30	39	30	,	,	,
cord-010499-yefxrj30	39	31	1988	1988	CD
cord-010499-yefxrj30	39	32	)	)	-RRB-
cord-010499-yefxrj30	39	33	.	.	.
cord-010499-yefxrj30	40	1	Our	-PRON-	PRP$
cord-010499-yefxrj30	40	2	purpose	purpose	NN
cord-010499-yefxrj30	40	3	was	be	VBD
cord-010499-yefxrj30	40	4	to	to	TO
cord-010499-yefxrj30	40	5	discover	discover	VB
cord-010499-yefxrj30	40	6	whether	whether	IN
cord-010499-yefxrj30	40	7	the	the	DT
cord-010499-yefxrj30	40	8	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	40	9	frameshifting	frameshifting	NN
cord-010499-yefxrj30	40	10	directed	direct	VBN
cord-010499-yefxrj30	40	11	by	by	IN
cord-010499-yefxrj30	40	12	a	a	DT
cord-010499-yefxrj30	40	13	very	very	RB
cord-010499-yefxrj30	40	14	short	short	JJ
cord-010499-yefxrj30	40	15	sequence	sequence	NN
cord-010499-yefxrj30	40	16	in	in	IN
cord-010499-yefxrj30	40	17	HiV-1	HiV-1	NNP
cord-010499-yefxrj30	40	18	could	could	MD
cord-010499-yefxrj30	40	19	be	be	VB
cord-010499-yefxrj30	40	20	reproduced	reproduce	VBN
cord-010499-yefxrj30	40	21	by	by	IN
cord-010499-yefxrj30	40	22	E	e	NN
cord-010499-yefxrj30	40	23	coli	coli	NNS
cord-010499-yefxrj30	40	24	ribosomes	ribosome	NNS
cord-010499-yefxrj30	40	25	in	in	IN
cord-010499-yefxrj30	40	26	vivo	vivo	NN
cord-010499-yefxrj30	40	27	,	,	,
cord-010499-yefxrj30	40	28	and	and	CC
cord-010499-yefxrj30	40	29	,	,	,
cord-010499-yefxrj30	40	30	if	if	IN
cord-010499-yefxrj30	40	31	so	so	RB
cord-010499-yefxrj30	40	32	,	,	,
cord-010499-yefxrj30	40	33	whether	whether	IN
cord-010499-yefxrj30	40	34	we	-PRON-	PRP
cord-010499-yefxrj30	40	35	could	could	MD
cord-010499-yefxrj30	40	36	alter	alter	VB
cord-010499-yefxrj30	40	37	the	the	DT
cord-010499-yefxrj30	40	38	rate	rate	NN
cord-010499-yefxrj30	40	39	of	of	IN
cord-010499-yefxrj30	40	40	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	40	41	by	by	IN
cord-010499-yefxrj30	40	42	regimens	regimen	NNS
cord-010499-yefxrj30	40	43	that	that	WDT
cord-010499-yefxrj30	40	44	change	change	VBP
cord-010499-yefxrj30	40	45	the	the	DT
cord-010499-yefxrj30	40	46	relative	relative	JJ
cord-010499-yefxrj30	40	47	abundance	abundance	NN
cord-010499-yefxrj30	40	48	of	of	IN
cord-010499-yefxrj30	40	49	key	key	JJ
cord-010499-yefxrj30	40	50	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	40	51	tRNAs	trna	NNS
cord-010499-yefxrj30	40	52	encoded	encode	VBN
cord-010499-yefxrj30	40	53	at	at	IN
cord-010499-yefxrj30	40	54	or	or	CC
cord-010499-yefxrj30	40	55	near	near	IN
cord-010499-yefxrj30	40	56	the	the	DT
cord-010499-yefxrj30	40	57	frameshift	frameshift	NN
cord-010499-yefxrj30	40	58	site	site	NN
cord-010499-yefxrj30	40	59	.	.	.
cord-010499-yefxrj30	41	1	Weiss	Weiss	NNP
cord-010499-yefxrj30	41	2	etal	etal	NNP
cord-010499-yefxrj30	41	3	.	.	.
cord-010499-yefxrj30	42	1	(	(	-LRB-
cord-010499-yefxrj30	42	2	1989	1989	CD
cord-010499-yefxrj30	42	3	)	)	-RRB-
cord-010499-yefxrj30	42	4	have	have	VBP
cord-010499-yefxrj30	42	5	also	also	RB
cord-010499-yefxrj30	42	6	reported	report	VBN
cord-010499-yefxrj30	42	7	that	that	IN
cord-010499-yefxrj30	42	8	a	a	DT
cord-010499-yefxrj30	42	9	52	52	CD
cord-010499-yefxrj30	42	10	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	42	11	fragment	fragment	NN
cord-010499-yefxrj30	42	12	from	from	IN
cord-010499-yefxrj30	42	13	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	42	14	is	be	VBZ
cord-010499-yefxrj30	42	15	sufficient	sufficient	JJ
cord-010499-yefxrj30	42	16	to	to	TO
cord-010499-yefxrj30	42	17	direct	direct	VB
cord-010499-yefxrj30	42	18	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	42	19	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	42	20	in	in	IN
cord-010499-yefxrj30	42	21	an	an	DT
cord-010499-yefxrj30	42	22	E.	E.	NNP
cord-010499-yefxrj30	42	23	coli	coli	NNS
cord-010499-yefxrj30	42	24	system	system	NN
cord-010499-yefxrj30	42	25	.	.	.
cord-010499-yefxrj30	43	1	In	in	IN
cord-010499-yefxrj30	43	2	this	this	DT
cord-010499-yefxrj30	43	3	report	report	NN
cord-010499-yefxrj30	43	4	we	-PRON-	PRP
cord-010499-yefxrj30	43	5	present	present	VBP
cord-010499-yefxrj30	43	6	evidence	evidence	NN
cord-010499-yefxrj30	43	7	that	that	IN
cord-010499-yefxrj30	43	8	a	a	DT
cord-010499-yefxrj30	43	9	much	much	RB
cord-010499-yefxrj30	43	10	shorter	short	JJR
cord-010499-yefxrj30	43	11	15	15	CD
cord-010499-yefxrj30	43	12	-	-	SYM
cord-010499-yefxrj30	43	13	17	17	CD
cord-010499-yefxrj30	43	14	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	43	15	sequence	sequence	NN
cord-010499-yefxrj30	43	16	derived	derive	VBN
cord-010499-yefxrj30	43	17	from	from	IN
cord-010499-yefxrj30	43	18	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	43	19	is	be	VBZ
cord-010499-yefxrj30	43	20	sufficient	sufficient	JJ
cord-010499-yefxrj30	43	21	to	to	TO
cord-010499-yefxrj30	43	22	direct	direct	VB
cord-010499-yefxrj30	43	23	the	the	DT
cord-010499-yefxrj30	43	24	same	same	JJ
cord-010499-yefxrj30	43	25	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	43	26	frameshift	frameshift	NN
cord-010499-yefxrj30	43	27	event	event	NN
cord-010499-yefxrj30	43	28	in	in	IN
cord-010499-yefxrj30	43	29	E.	E.	NNP
cord-010499-yefxrj30	43	30	coli	coli	NNS
cord-010499-yefxrj30	43	31	as	as	IN
cord-010499-yefxrj30	43	32	in	in	IN
cord-010499-yefxrj30	43	33	eukaryotes	eukaryote	NNS
cord-010499-yefxrj30	43	34	.	.	.
cord-010499-yefxrj30	44	1	We	-PRON-	PRP
cord-010499-yefxrj30	44	2	also	also	RB
cord-010499-yefxrj30	44	3	show	show	VBP
cord-010499-yefxrj30	44	4	that	that	IN
cord-010499-yefxrj30	44	5	in	in	IN
cord-010499-yefxrj30	44	6	E.	E.	NNP
cord-010499-yefxrj30	44	7	coli	coli	VBZ
cord-010499-yefxrj30	44	8	the	the	DT
cord-010499-yefxrj30	44	9	rate	rate	NN
cord-010499-yefxrj30	44	10	of	of	IN
cord-010499-yefxrj30	44	11	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	44	12	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	44	13	on	on	IN
cord-010499-yefxrj30	44	14	that	that	DT
cord-010499-yefxrj30	44	15	sequence	sequence	NN
cord-010499-yefxrj30	44	16	can	can	MD
cord-010499-yefxrj30	44	17	be	be	VB
cord-010499-yefxrj30	44	18	increased	increase	VBN
cord-010499-yefxrj30	44	19	by	by	IN
cord-010499-yefxrj30	44	20	limitation	limitation	NN
cord-010499-yefxrj30	44	21	for	for	IN
cord-010499-yefxrj30	44	22	leucine	leucine	NN
cord-010499-yefxrj30	44	23	,	,	,
cord-010499-yefxrj30	44	24	the	the	DT
cord-010499-yefxrj30	44	25	amino	amino	NN
cord-010499-yefxrj30	44	26	acid	acid	NN
cord-010499-yefxrj30	44	27	encoded	encode	VBN
cord-010499-yefxrj30	44	28	at	at	IN
cord-010499-yefxrj30	44	29	the	the	DT
cord-010499-yefxrj30	44	30	frameshift	frameshift	NN
cord-010499-yefxrj30	44	31	site	site	NN
cord-010499-yefxrj30	44	32	.	.	.
cord-010499-yefxrj30	45	1	Protein	protein	NN
cord-010499-yefxrj30	45	2	sequence	sequence	NN
cord-010499-yefxrj30	45	3	analysis	analysis	NN
cord-010499-yefxrj30	45	4	of	of	IN
cord-010499-yefxrj30	45	5	the	the	DT
cord-010499-yefxrj30	45	6	product	product	NN
cord-010499-yefxrj30	45	7	indicates	indicate	VBZ
cord-010499-yefxrj30	45	8	the	the	DT
cord-010499-yefxrj30	45	9	occurrence	occurrence	NN
cord-010499-yefxrj30	45	10	of	of	IN
cord-010499-yefxrj30	45	11	two	two	CD
cord-010499-yefxrj30	45	12	siightiy	siightiy	NNS
cord-010499-yefxrj30	45	13	different	different	JJ
cord-010499-yefxrj30	45	14	mechanisms	mechanism	NNS
cord-010499-yefxrj30	45	15	of	of	IN
cord-010499-yefxrj30	45	16	shifting	shift	VBG
cord-010499-yefxrj30	45	17	.	.	.
cord-010499-yefxrj30	46	1	The	the	DT
cord-010499-yefxrj30	46	2	strategy	strategy	NN
cord-010499-yefxrj30	46	3	behind	behind	IN
cord-010499-yefxrj30	46	4	the	the	DT
cord-010499-yefxrj30	46	5	construction	construction	NN
cord-010499-yefxrj30	46	6	of	of	IN
cord-010499-yefxrj30	46	7	our	-PRON-	PRP$
cord-010499-yefxrj30	46	8	assay	assay	NN
cord-010499-yefxrj30	46	9	system	system	NN
cord-010499-yefxrj30	46	10	for	for	IN
cord-010499-yefxrj30	46	11	ribosomai	ribosomai	NNP
cord-010499-yefxrj30	46	12	frameshifting	frameshifting	NNP
cord-010499-yefxrj30	46	13	may	may	MD
cord-010499-yefxrj30	46	14	be	be	VB
cord-010499-yefxrj30	46	15	understood	understand	VBN
cord-010499-yefxrj30	46	16	with	with	IN
cord-010499-yefxrj30	46	17	reference	reference	NN
cord-010499-yefxrj30	46	18	to	to	IN
cord-010499-yefxrj30	46	19	Fig	Fig	NNP
cord-010499-yefxrj30	46	20	.	.	.
cord-010499-yefxrj30	47	1	1	1	LS
cord-010499-yefxrj30	47	2	.	.	.
cord-010499-yefxrj30	48	1	When	when	WRB
cord-010499-yefxrj30	48	2	eukaryotic	eukaryotic	JJ
cord-010499-yefxrj30	48	3	ribosomes	ribosome	NNS
cord-010499-yefxrj30	48	4	decode	decode	VBP
cord-010499-yefxrj30	48	5	the	the	DT
cord-010499-yefxrj30	48	6	HIV	HIV	NNP
cord-010499-yefxrj30	48	7	mRNA	mRNA	NNP
cord-010499-yefxrj30	48	8	sequence	sequence	NN
cord-010499-yefxrj30	48	9	.	.	.
cord-010499-yefxrj30	48	10	.	.	.
cord-010499-yefxrj30	48	11	.	.	.
cord-010499-yefxrj30	49	1	UUUUUUAGGG	UUUUUUAGGG	NNP
cord-010499-yefxrj30	49	2	.	.	.
cord-010499-yefxrj30	49	3	.	.	.
cord-010499-yefxrj30	49	4	.	.	.
cord-010499-yefxrj30	50	1	,	,	,
cord-010499-yefxrj30	50	2	shown	show	VBN
cord-010499-yefxrj30	50	3	as	as	IN
cord-010499-yefxrj30	50	4	nucleotides	nucleotide	NNS
cord-010499-yefxrj30	50	5	1	1	CD
cord-010499-yefxrj30	50	6	-	-	SYM
cord-010499-yefxrj30	50	7	10	10	CD
cord-010499-yefxrj30	50	8	in	in	IN
cord-010499-yefxrj30	50	9	Fig	Fig	NNP
cord-010499-yefxrj30	50	10	.	.	.
cord-010499-yefxrj30	51	1	1A	1a	LS
cord-010499-yefxrj30	51	2	,	,	,
cord-010499-yefxrj30	51	3	the	the	DT
cord-010499-yefxrj30	51	4	adenine	adenine	NN
cord-010499-yefxrj30	51	5	at	at	IN
cord-010499-yefxrj30	51	6	position	position	NN
cord-010499-yefxrj30	51	7	7	7	CD
cord-010499-yefxrj30	51	8	appears	appear	VBZ
cord-010499-yefxrj30	51	9	to	to	TO
cord-010499-yefxrj30	51	10	be	be	VB
cord-010499-yefxrj30	51	11	read	read	VBN
cord-010499-yefxrj30	51	12	twice	twice	RB
cord-010499-yefxrj30	51	13	:	:	:
cord-010499-yefxrj30	51	14	first	first	RB
cord-010499-yefxrj30	51	15	,	,	,
cord-010499-yefxrj30	51	16	as	as	IN
cord-010499-yefxrj30	51	17	the	the	DT
cord-010499-yefxrj30	51	18	third	third	JJ
cord-010499-yefxrj30	51	19	position	position	NN
cord-010499-yefxrj30	51	20	of	of	IN
cord-010499-yefxrj30	51	21	a	a	DT
cord-010499-yefxrj30	51	22	leucine	leucine	NN
cord-010499-yefxrj30	51	23	codon	codon	NN
cord-010499-yefxrj30	51	24	(	(	-LRB-
cord-010499-yefxrj30	51	25	UUA	UUA	NNP
cord-010499-yefxrj30	51	26	)	)	-RRB-
cord-010499-yefxrj30	51	27	and	and	CC
cord-010499-yefxrj30	51	28	then	then	RB
cord-010499-yefxrj30	51	29	again	again	RB
cord-010499-yefxrj30	51	30	as	as	IN
cord-010499-yefxrj30	51	31	the	the	DT
cord-010499-yefxrj30	51	32	first	first	JJ
cord-010499-yefxrj30	51	33	position	position	NN
cord-010499-yefxrj30	51	34	in	in	IN
cord-010499-yefxrj30	51	35	the	the	DT
cord-010499-yefxrj30	51	36	overlapping	overlap	VBG
cord-010499-yefxrj30	51	37	arginine	arginine	NN
cord-010499-yefxrj30	51	38	codon	codon	NN
cord-010499-yefxrj30	51	39	(	(	-LRB-
cord-010499-yefxrj30	51	40	AGG	AGG	NNP
cord-010499-yefxrj30	51	41	Ratner	Ratner	NNP
cord-010499-yefxrj30	51	42	et	et	NNP
cord-010499-yefxrj30	51	43	al	al	NNP
cord-010499-yefxrj30	51	44	.	.	.
cord-010499-yefxrj30	52	1	(	(	-LRB-
cord-010499-yefxrj30	52	2	1985	1985	CD
cord-010499-yefxrj30	52	3	)	)	-RRB-
cord-010499-yefxrj30	52	4	.	.	.
cord-010499-yefxrj30	53	1	In	in	IN
cord-010499-yefxrj30	53	2	a	a	DT
cord-010499-yefxrj30	53	3	heterologous	heterologous	JJ
cord-010499-yefxrj30	53	4	mammalian	mammalian	NN
cord-010499-yefxrj30	53	5	in	in	IN
cord-010499-yefxrj30	53	6	w	w	NNP
cord-010499-yefxrj30	53	7	/	/	SYM
cord-010499-yefxrj30	53	8	ro	ro	NNP
cord-010499-yefxrj30	53	9	translation	translation	NN
cord-010499-yefxrj30	53	10	system	system	NN
cord-010499-yefxrj30	53	11	,	,	,
cord-010499-yefxrj30	53	12	most	most	JJS
cord-010499-yefxrj30	53	13	of	of	IN
cord-010499-yefxrj30	53	14	the	the	DT
cord-010499-yefxrj30	53	15	frameshift	frameshift	NN
cord-010499-yefxrj30	53	16	product	product	NN
cord-010499-yefxrj30	53	17	has	have	VBZ
cord-010499-yefxrj30	53	18	the	the	DT
cord-010499-yefxrj30	53	19	amino	amino	NN
cord-010499-yefxrj30	53	20	acid	acid	NN
cord-010499-yefxrj30	53	21	sequence	sequence	NN
cord-010499-yefxrj30	53	22	.	.	.
cord-010499-yefxrj30	53	23	.	.	.
cord-010499-yefxrj30	53	24	.	.	.
cord-010499-yefxrj30	54	1	Asn	Asn	NNP
cord-010499-yefxrj30	54	2	-	-	HYPH
cord-010499-yefxrj30	54	3	Phe	Phe	NNP
cord-010499-yefxrj30	54	4	-	-	HYPH
cord-010499-yefxrj30	54	5	Leu	Leu	NNP
cord-010499-yefxrj30	54	6	-	-	HYPH
cord-010499-yefxrj30	54	7	Arg	Arg	NNP
cord-010499-yefxrj30	55	1	(	(	-LRB-
cord-010499-yefxrj30	55	2	Jacks	Jacks	NNP
cord-010499-yefxrj30	55	3	et	et	NNP
cord-010499-yefxrj30	55	4	al	al	NNP
cord-010499-yefxrj30	55	5	.	.	NNP
cord-010499-yefxrj30	55	6	,	,	,
cord-010499-yefxrj30	55	7	1988b	1988b	CD
cord-010499-yefxrj30	55	8	)	)	-RRB-
cord-010499-yefxrj30	55	9	,	,	,
cord-010499-yefxrj30	55	10	where	where	WRB
cord-010499-yefxrj30	55	11	Leu	Leu	NNP
cord-010499-yefxrj30	55	12	is	be	VBZ
cord-010499-yefxrj30	55	13	encoded	encode	VBN
cord-010499-yefxrj30	55	14	by	by	IN
cord-010499-yefxrj30	55	15	positions	position	NNS
cord-010499-yefxrj30	55	16	5	5	CD
cord-010499-yefxrj30	55	17	-	-	SYM
cord-010499-yefxrj30	55	18	7	7	CD
cord-010499-yefxrj30	55	19	and	and	CC
cord-010499-yefxrj30	55	20	Arg	Arg	NNP
cord-010499-yefxrj30	55	21	is	be	VBZ
cord-010499-yefxrj30	55	22	encoded	encode	VBN
cord-010499-yefxrj30	55	23	by	by	IN
cord-010499-yefxrj30	55	24	positions	position	NNS
cord-010499-yefxrj30	55	25	7	7	CD
cord-010499-yefxrj30	55	26	-	-	SYM
cord-010499-yefxrj30	55	27	9	9	CD
cord-010499-yefxrj30	55	28	.	.	.
cord-010499-yefxrj30	56	1	Some	some	DT
cord-010499-yefxrj30	56	2	mutations	mutation	NNS
cord-010499-yefxrj30	56	3	that	that	WDT
cord-010499-yefxrj30	56	4	result	result	VBP
cord-010499-yefxrj30	56	5	in	in	IN
cord-010499-yefxrj30	56	6	increased	increase	VBN
cord-010499-yefxrj30	56	7	or	or	CC
cord-010499-yefxrj30	56	8	decreased	decrease	VBN
cord-010499-yefxrj30	56	9	expression	expression	NN
cord-010499-yefxrj30	56	10	of	of	IN
cord-010499-yefxrj30	56	11	frameshift	frameshift	NN
cord-010499-yefxrj30	56	12	products	product	NNS
cord-010499-yefxrj30	56	13	in	in	IN
cord-010499-yefxrj30	56	14	a	a	DT
cord-010499-yefxrj30	56	15	heterologous	heterologous	JJ
cord-010499-yefxrj30	56	16	test	test	NN
cord-010499-yefxrj30	56	17	system	system	NN
cord-010499-yefxrj30	56	18	are	be	VBP
cord-010499-yefxrj30	56	19	shown	show	VBN
cord-010499-yefxrj30	56	20	above	above	IN
cord-010499-yefxrj30	56	21	and	and	CC
cord-010499-yefxrj30	56	22	below	below	IN
cord-010499-yefxrj30	56	23	the	the	DT
cord-010499-yefxrj30	56	24	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	56	25	sequence	sequence	NN
cord-010499-yefxrj30	56	26	,	,	,
cord-010499-yefxrj30	56	27	respectively	respectively	RB
cord-010499-yefxrj30	56	28	(	(	-LRB-
cord-010499-yefxrj30	56	29	Wilson	Wilson	NNP
cord-010499-yefxrj30	56	30	ef	ef	NNP
cord-010499-yefxrj30	56	31	a/.	a/.	NNP
cord-010499-yefxrj30	56	32	,	,	,
cord-010499-yefxrj30	56	33	1988	1988	CD
cord-010499-yefxrj30	56	34	)	)	-RRB-
cord-010499-yefxrj30	56	35	.	.	.
cord-010499-yefxrj30	57	1	'	'	''
cord-010499-yefxrj30	58	1	N	N	NNP
cord-010499-yefxrj30	58	2	'	'	POS
cord-010499-yefxrj30	58	3	signifies	signify	VBZ
cord-010499-yefxrj30	58	4	a	a	DT
cord-010499-yefxrj30	58	5	mutation	mutation	NN
cord-010499-yefxrj30	58	6	to	to	IN
cord-010499-yefxrj30	58	7	any	any	DT
cord-010499-yefxrj30	58	8	non	non	JJ
cord-010499-yefxrj30	58	9	-	-	JJ
cord-010499-yefxrj30	58	10	U	u	JJ
cord-010499-yefxrj30	58	11	base	base	NN
cord-010499-yefxrj30	58	12	.	.	.
cord-010499-yefxrj30	59	1	Double	double	JJ
cord-010499-yefxrj30	59	2	underlines	underline	NNS
cord-010499-yefxrj30	59	3	at	at	IN
cord-010499-yefxrj30	59	4	positions	position	NNS
cord-010499-yefxrj30	59	5	-10	-10	NN
cord-010499-yefxrj30	59	6	and	and	CC
cord-010499-yefxrj30	59	7	+16	+16	NNP
cord-010499-yefxrj30	59	8	mark	mark	VBP
cord-010499-yefxrj30	59	9	the	the	DT
cord-010499-yefxrj30	59	10	boundaries	boundary	NNS
cord-010499-yefxrj30	59	11	of	of	IN
cord-010499-yefxrj30	59	12	a	a	DT
cord-010499-yefxrj30	59	13	fragment	fragment	NN
cord-010499-yefxrj30	59	14	that	that	WDT
cord-010499-yefxrj30	59	15	directs	direct	VBZ
cord-010499-yefxrj30	59	16	the	the	DT
cord-010499-yefxrj30	59	17	synthesis	synthesis	NN
cord-010499-yefxrj30	59	18	of	of	IN
cord-010499-yefxrj30	59	19	a	a	DT
cord-010499-yefxrj30	59	20	frameshift	frameshift	NN
cord-010499-yefxrj30	59	21	protein	protein	NN
cord-010499-yefxrj30	59	22	product	product	NN
cord-010499-yefxrj30	59	23	in	in	IN
cord-010499-yefxrj30	59	24	a	a	DT
cord-010499-yefxrj30	59	25	heterologous	heterologous	JJ
cord-010499-yefxrj30	59	26	yeast	yeast	NN
cord-010499-yefxrj30	59	27	system	system	NN
cord-010499-yefxrj30	59	28	(	(	-LRB-
cord-010499-yefxrj30	59	29	Wilson	Wilson	NNP
cord-010499-yefxrj30	59	30	et	et	NNP
cord-010499-yefxrj30	59	31	at	at	IN
cord-010499-yefxrj30	59	32	..	..	.
cord-010499-yefxrj30	59	33	1988	1988	CD
cord-010499-yefxrj30	59	34	)	)	-RRB-
cord-010499-yefxrj30	59	35	.	.	.
cord-010499-yefxrj30	60	1	The	the	DT
cord-010499-yefxrj30	60	2	singly	singly	RB
cord-010499-yefxrj30	60	3	underlined	underline	VBN
cord-010499-yefxrj30	60	4	G	g	NN
cord-010499-yefxrj30	60	5	at	at	IN
cord-010499-yefxrj30	60	6	position	position	NN
cord-010499-yefxrj30	60	7	-6	-6	:
cord-010499-yefxrj30	60	8	is	be	VBZ
cord-010499-yefxrj30	60	9	the	the	DT
cord-010499-yefxrj30	60	10	5	5	CD
cord-010499-yefxrj30	60	11	'	'	''
cord-010499-yefxrj30	60	12	boundary	boundary	NN
cord-010499-yefxrj30	60	13	of	of	IN
cord-010499-yefxrj30	60	14	a	a	DT
cord-010499-yefxrj30	60	15	fragment	fragment	NN
cord-010499-yefxrj30	60	16	that	that	WDT
cord-010499-yefxrj30	60	17	directs	direct	VBZ
cord-010499-yefxrj30	60	18	the	the	DT
cord-010499-yefxrj30	60	19	synthesis	synthesis	NN
cord-010499-yefxrj30	60	20	of	of	IN
cord-010499-yefxrj30	60	21	a	a	DT
cord-010499-yefxrj30	60	22	frameshift	frameshift	NN
cord-010499-yefxrj30	60	23	protein	protein	NN
cord-010499-yefxrj30	60	24	product	product	NN
cord-010499-yefxrj30	60	25	in	in	IN
cord-010499-yefxrj30	60	26	a	a	DT
cord-010499-yefxrj30	60	27	mammalian	mammalian	JJ
cord-010499-yefxrj30	60	28	iri	iri	FW
cord-010499-yefxrj30	60	29	vitro	vitro	FW
cord-010499-yefxrj30	60	30	system	system	NN
cord-010499-yefxrj30	60	31	(	(	-LRB-
cord-010499-yefxrj30	60	32	Jacks	Jacks	NNP
cord-010499-yefxrj30	60	33	e	e	NN
cord-010499-yefxrj30	60	34	(	(	-LRB-
cord-010499-yefxrj30	60	35	al	al	NNP
cord-010499-yefxrj30	60	36	.	.	NNP
cord-010499-yefxrj30	60	37	,	,	,
cord-010499-yefxrj30	60	38	1988b	1988b	CD
cord-010499-yefxrj30	60	39	)	)	-RRB-
cord-010499-yefxrj30	60	40	.	.	.
cord-010499-yefxrj30	61	1	B.	B.	NNP
cord-010499-yefxrj30	61	2	and	and	CC
cord-010499-yefxrj30	61	3	C.	C.	NNP
cord-010499-yefxrj30	61	4	A	A	NNP
cord-010499-yefxrj30	61	5	portion	portion	NN
cord-010499-yefxrj30	61	6	of	of	IN
cord-010499-yefxrj30	61	7	&	&	CC
cord-010499-yefxrj30	61	8	ie	ie	NNP
cord-010499-yefxrj30	62	1	mRNA	mRNA	NNP
cord-010499-yefxrj30	62	2	sequences	sequence	NNS
cord-010499-yefxrj30	62	3	expressed	express	VBD
cord-010499-yefxrj30	62	4	from	from	IN
cord-010499-yefxrj30	62	5	tecZframeshift	teczframeshift	DT
cord-010499-yefxrj30	62	6	alleles	allele	NNS
cord-010499-yefxrj30	62	7	HIV13	HIV13	NNP
cord-010499-yefxrj30	62	8	,	,	,
cord-010499-yefxrj30	62	9	HIV13-A3	HIV13-A3	NNP
cord-010499-yefxrj30	62	10	,	,	,
cord-010499-yefxrj30	62	11	HIV201	HIV201	NNP
cord-010499-yefxrj30	62	12	,	,	,
cord-010499-yefxrj30	62	13	and	and	CC
cord-010499-yefxrj30	62	14	HIV201-U7	HIV201-U7	NNS
cord-010499-yefxrj30	62	15	are	be	VBP
cord-010499-yefxrj30	62	16	depicted	depict	VBN
cord-010499-yefxrj30	62	17	.	.	.
cord-010499-yefxrj30	63	1	Numbers	number	NNS
cord-010499-yefxrj30	63	2	above	above	IN
cord-010499-yefxrj30	63	3	the	the	DT
cord-010499-yefxrj30	63	4	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	63	5	sequence	sequence	NN
cord-010499-yefxrj30	63	6	correspond	correspond	VBP
cord-010499-yefxrj30	63	7	to	to	IN
cord-010499-yefxrj30	63	8	analogous	analogous	JJ
cord-010499-yefxrj30	63	9	positions	position	NNS
cord-010499-yefxrj30	63	10	of	of	IN
cord-010499-yefxrj30	63	11	the	the	DT
cord-010499-yefxrj30	63	12	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	63	13	gag	gag	NN
cord-010499-yefxrj30	63	14	-	-	HYPH
cord-010499-yefxrj30	63	15	po	po	NN
cord-010499-yefxrj30	63	16	/	/	SYM
cord-010499-yefxrj30	63	17	junction	junction	NN
cord-010499-yefxrj30	63	18	.	.	.
cord-010499-yefxrj30	64	1	Doubly	doubly	RB
cord-010499-yefxrj30	64	2	underlined	underline	VBN
cord-010499-yefxrj30	64	3	nucieotides	nucieotide	NNS
cord-010499-yefxrj30	64	4	mark	mark	VBP
cord-010499-yefxrj30	64	5	the	the	DT
cord-010499-yefxrj30	64	6	twundaries	twundarie	NNS
cord-010499-yefxrj30	64	7	of	of	IN
cord-010499-yefxrj30	64	8	sequence	sequence	NN
cord-010499-yefxrj30	65	1	thai	thai	NNP
cord-010499-yefxrj30	65	2	is	be	VBZ
cord-010499-yefxrj30	65	3	consen	consen	NNP
cord-010499-yefxrj30	65	4	/	/	SYM
cord-010499-yefxrj30	65	5	ed	ed	NN
cord-010499-yefxrj30	65	6	with	with	IN
cord-010499-yefxrj30	65	7	respect	respect	NN
cord-010499-yefxrj30	65	8	to	to	IN
cord-010499-yefxrj30	65	9	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	65	10	.	.	.
cord-010499-yefxrj30	66	1	Synthesis	synthesis	NN
cord-010499-yefxrj30	66	2	of	of	IN
cord-010499-yefxrj30	66	3	p	p	NN
cord-010499-yefxrj30	66	4	-	-	HYPH
cord-010499-yefxrj30	66	5	gaiactosidase	gaiactosidase	NN
cord-010499-yefxrj30	66	6	from	from	IN
cord-010499-yefxrj30	66	7	the	the	DT
cord-010499-yefxrj30	66	8	alleles	allele	NNS
cord-010499-yefxrj30	66	9	requires	require	VBZ
cord-010499-yefxrj30	66	10	a	a	DT
cord-010499-yefxrj30	66	11	leftward	leftward	JJ
cord-010499-yefxrj30	66	12	frameshift	frameshift	NN
cord-010499-yefxrj30	66	13	.	.	.
cord-010499-yefxrj30	67	1	Amino	amino	NN
cord-010499-yefxrj30	67	2	acids	acid	NNS
cord-010499-yefxrj30	67	3	are	be	VBP
cord-010499-yefxrj30	67	4	shown	show	VBN
cord-010499-yefxrj30	67	5	for	for	IN
cord-010499-yefxrj30	67	6	the	the	DT
cord-010499-yefxrj30	67	7	mature	mature	JJ
cord-010499-yefxrj30	67	8	protein	protein	NN
cord-010499-yefxrj30	67	9	,	,	,
cord-010499-yefxrj30	67	10	afler	afler	NN
cord-010499-yefxrj30	67	11	in	in	IN
cord-010499-yefxrj30	67	12	vivo	vivo	NN
cord-010499-yefxrj30	67	13	cleavage	cleavage	NN
cord-010499-yefxrj30	67	14	of	of	IN
cord-010499-yefxrj30	67	15	the	the	DT
cord-010499-yefxrj30	67	16	initiating	initiate	VBG
cord-010499-yefxrj30	67	17	W	w	NN
cord-010499-yefxrj30	67	18	-	-	HYPH
cord-010499-yefxrj30	67	19	terminal	terminal	NN
cord-010499-yefxrj30	67	20	fomiyl	fomiyl	NNP
cord-010499-yefxrj30	67	21	-	-	HYPH
cord-010499-yefxrj30	67	22	met	meet	VBN
cord-010499-yefxrj30	67	23	residue	residue	NN
cord-010499-yefxrj30	67	24	.	.	.
cord-010499-yefxrj30	68	1	Constructs	construct	NNS
cord-010499-yefxrj30	68	2	pHIV13	pHIV13	NNP
cord-010499-yefxrj30	68	3	and	and	CC
cord-010499-yefxrj30	68	4	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	68	5	.	.	.
cord-010499-yefxrj30	69	1	and	and	CC
cord-010499-yefxrj30	69	2	their	-PRON-	PRP$
cord-010499-yefxrj30	69	3	variants	variant	NNS
cord-010499-yefxrj30	69	4	pHIV13-A3	pHIV13-A3	NNP
cord-010499-yefxrj30	69	5	and	and	CC
cord-010499-yefxrj30	69	6	pHIV201-U7	pHIV201-U7	NNP
cord-010499-yefxrj30	69	7	,	,	,
cord-010499-yefxrj30	69	8	are	be	VBP
cord-010499-yefxrj30	69	9	described	describe	VBN
cord-010499-yefxrj30	69	10	in	in	IN
cord-010499-yefxrj30	69	11	Fig	Fig	NNP
cord-010499-yefxrj30	69	12	.	.	.
cord-010499-yefxrj30	70	1	1	1	LS
cord-010499-yefxrj30	70	2	.	.	.
cord-010499-yefxrj30	71	1	(	(	-LRB-
cord-010499-yefxrj30	71	2	The	the	DT
cord-010499-yefxrj30	71	3	sequence	sequence	NN
cord-010499-yefxrj30	71	4	of	of	IN
cord-010499-yefxrj30	71	5	the	the	DT
cord-010499-yefxrj30	71	6	critical	critical	JJ
cord-010499-yefxrj30	71	7	heptanucleotide	heptanucleotide	NN
cord-010499-yefxrj30	71	8	at	at	IN
cord-010499-yefxrj30	71	9	the	the	DT
cord-010499-yefxrj30	71	10	frameshift	frameshift	NN
cord-010499-yefxrj30	71	11	site	site	NN
cord-010499-yefxrj30	71	12	is	be	VBZ
cord-010499-yefxrj30	71	13	shown	show	VBN
cord-010499-yefxrj30	71	14	in	in	IN
cord-010499-yefxrj30	71	15	parenthesis	parenthesis	NN
cord-010499-yefxrj30	71	16	after	after	IN
cord-010499-yefxrj30	71	17	each	each	DT
cord-010499-yefxrj30	71	18	construct	construct	NN
cord-010499-yefxrj30	71	19	's	's	POS
cord-010499-yefxrj30	71	20	designation	designation	NN
cord-010499-yefxrj30	71	21	.	.	.
cord-010499-yefxrj30	71	22	)	)	-RRB-
cord-010499-yefxrj30	72	1	All	all	DT
cord-010499-yefxrj30	72	2	constructs	construct	NNS
cord-010499-yefxrj30	72	3	were	be	VBD
cord-010499-yefxrj30	72	4	transformed	transform	VBN
cord-010499-yefxrj30	72	5	into	into	IN
cord-010499-yefxrj30	72	6	a	a	DT
cord-010499-yefxrj30	72	7	derivative	derivative	NN
cord-010499-yefxrj30	72	8	of	of	IN
cord-010499-yefxrj30	72	9	CP79	CP79	NNP
cord-010499-yefxrj30	72	10	{	{	-LRB-
cord-010499-yefxrj30	72	11	relA2	relA2	.
cord-010499-yefxrj30	72	12	thr	thr	NNP
cord-010499-yefxrj30	72	13	'	'	POS
cord-010499-yefxrj30	72	14	leu	leu	NNP
cord-010499-yefxrj30	72	15	his	-PRON-	PRP$
cord-010499-yefxrj30	72	16	~	~	NFP
cord-010499-yefxrj30	72	17	arg~	arg~	CD
cord-010499-yefxrj30	72	18	thi~	thi~	CD
cord-010499-yefxrj30	72	19	)	)	-RRB-
cord-010499-yefxrj30	72	20	carrying	carry	VBG
cord-010499-yefxrj30	72	21	a	a	DT
cord-010499-yefxrj30	72	22	complete	complete	JJ
cord-010499-yefxrj30	72	23	deletion	deletion	NN
cord-010499-yefxrj30	72	24	of	of	IN
cord-010499-yefxrj30	72	25	lacZ.	lacZ.	NNP
cord-010499-yefxrj30	72	26	Methods	method	NNS
cord-010499-yefxrj30	72	27	of	of	IN
cord-010499-yefxrj30	72	28	cultivation	cultivation	NN
cord-010499-yefxrj30	72	29	,	,	,
cord-010499-yefxrj30	72	30	and	and	CC
cord-010499-yefxrj30	72	31	enzyme	enzyme	NN
cord-010499-yefxrj30	72	32	and	and	CC
cord-010499-yefxrj30	72	33	protein	protein	NN
cord-010499-yefxrj30	72	34	assay	assay	NN
cord-010499-yefxrj30	72	35	were	be	VBD
cord-010499-yefxrj30	72	36	as	as	IN
cord-010499-yefxrj30	72	37	described	describe	VBN
cord-010499-yefxrj30	72	38	previously	previously	RB
cord-010499-yefxrj30	72	39	Peter	Peter	NNP
cord-010499-yefxrj30	72	40	etal	etal	NNP
cord-010499-yefxrj30	72	41	.	.	NNP
cord-010499-yefxrj30	72	42	,	,	,
cord-010499-yefxrj30	72	43	1992	1992	CD
cord-010499-yefxrj30	72	44	)	)	-RRB-
cord-010499-yefxrj30	72	45	.	.	.
cord-010499-yefxrj30	73	1	Cells	cell	NNS
cord-010499-yefxrj30	73	2	were	be	VBD
cord-010499-yefxrj30	73	3	grown	grow	VBN
cord-010499-yefxrj30	73	4	into	into	IN
cord-010499-yefxrj30	73	5	exponential	exponential	JJ
cord-010499-yefxrj30	73	6	phase	phase	NN
cord-010499-yefxrj30	73	7	in	in	IN
cord-010499-yefxrj30	73	8	M63-glucose	M63-glucose	NNP
cord-010499-yefxrj30	73	9	medium	medium	NN
cord-010499-yefxrj30	73	10	supplemenled	supplemenle	VBD
cord-010499-yefxrj30	73	11	with	with	IN
cord-010499-yefxrj30	73	12	all	all	DT
cord-010499-yefxrj30	73	13	required	require	VBN
cord-010499-yefxrj30	73	14	amino	amino	NN
cord-010499-yefxrj30	73	15	acids	acid	NNS
cord-010499-yefxrj30	73	16	plus	plus	CC
cord-010499-yefxrj30	73	17	He	-PRON-	PRP
cord-010499-yefxrj30	73	18	and	and	CC
cord-010499-yefxrj30	73	19	Val	Val	NNP
cord-010499-yefxrj30	73	20	.	.	.
cord-010499-yefxrj30	74	1	The	the	DT
cord-010499-yefxrj30	74	2	lac	lac	NNP
cord-010499-yefxrj30	74	3	promoter	promoter	NN
cord-010499-yefxrj30	74	4	was	be	VBD
cord-010499-yefxrj30	74	5	induced	induce	VBN
cord-010499-yefxrj30	74	6	(	(	-LRB-
cord-010499-yefxrj30	74	7	2mM	2mm	CD
cord-010499-yefxrj30	74	8	IPTG	IPTG	NNP
cord-010499-yefxrj30	74	9	and	and	CC
cord-010499-yefxrj30	74	10	2.5mM	2.5mm	CD
cord-010499-yefxrj30	74	11	cAMP	camp	NN
cord-010499-yefxrj30	74	12	)	)	-RRB-
cord-010499-yefxrj30	74	13	for	for	IN
cord-010499-yefxrj30	74	14	about	about	RB
cord-010499-yefxrj30	74	15	one	one	CD
cord-010499-yefxrj30	74	16	doubling	doubling	NN
cord-010499-yefxrj30	74	17	.	.	.
cord-010499-yefxrj30	75	1	Data	datum	NNS
cord-010499-yefxrj30	75	2	are	be	VBP
cord-010499-yefxrj30	75	3	reported	report	VBN
cord-010499-yefxrj30	75	4	±	±	NNP
cord-010499-yefxrj30	75	5	standard	standard	JJ
cord-010499-yefxrj30	75	6	error	error	NN
cord-010499-yefxrj30	75	7	of	of	IN
cord-010499-yefxrj30	75	8	the	the	DT
cord-010499-yefxrj30	75	9	mean	mean	NN
cord-010499-yefxrj30	75	10	,	,	,
cord-010499-yefxrj30	75	11	with	with	IN
cord-010499-yefxrj30	75	12	the	the	DT
cord-010499-yefxrj30	75	13	number	number	NN
cord-010499-yefxrj30	75	14	of	of	IN
cord-010499-yefxrj30	75	15	replicate	replicate	VBP
cord-010499-yefxrj30	75	16	induced	induce	VBN
cord-010499-yefxrj30	75	17	cultures	culture	NNS
cord-010499-yefxrj30	75	18	in	in	IN
cord-010499-yefxrj30	75	19	parentheses	parenthesis	NNS
cord-010499-yefxrj30	75	20	.	.	.
cord-010499-yefxrj30	76	1	These	these	DT
cord-010499-yefxrj30	76	2	values	value	NNS
cord-010499-yefxrj30	76	3	include	include	VBP
cord-010499-yefxrj30	76	4	all	all	PDT
cord-010499-yefxrj30	76	5	the	the	DT
cord-010499-yefxrj30	76	6	unstarved	unstarved	JJ
cord-010499-yefxrj30	76	7	control	control	NN
cord-010499-yefxrj30	76	8	cultures	culture	NNS
cord-010499-yefxrj30	76	9	from	from	IN
cord-010499-yefxrj30	76	10	the	the	DT
cord-010499-yefxrj30	76	11	various	various	JJ
cord-010499-yefxrj30	76	12	starvation	starvation	NN
cord-010499-yefxrj30	76	13	experiments	experiment	NNS
cord-010499-yefxrj30	76	14	.	.	.
cord-010499-yefxrj30	77	1	to	to	TO
cord-010499-yefxrj30	77	2	take	take	VB
cord-010499-yefxrj30	77	3	place	place	NN
cord-010499-yefxrj30	77	4	in	in	IN
cord-010499-yefxrj30	77	5	about	about	RB
cord-010499-yefxrj30	77	6	10	10	CD
cord-010499-yefxrj30	77	7	%	%	NN
cord-010499-yefxrj30	77	8	of	of	IN
cord-010499-yefxrj30	77	9	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	77	10	transits	transit	NNS
cord-010499-yefxrj30	77	11	(	(	-LRB-
cord-010499-yefxrj30	77	12	Jacks	Jacks	NNP
cord-010499-yefxrj30	77	13	etai	etai	NNP
cord-010499-yefxrj30	77	14	.	.	.
cord-010499-yefxrj30	78	1	1988b	1988b	CD
cord-010499-yefxrj30	78	2	)	)	-RRB-
cord-010499-yefxrj30	78	3	.	.	.
cord-010499-yefxrj30	79	1	in	in	IN
cord-010499-yefxrj30	79	2	HiV-1	HiV-1	NNP
cord-010499-yefxrj30	79	3	,	,	,
cord-010499-yefxrj30	79	4	the	the	DT
cord-010499-yefxrj30	79	5	outcome	outcome	NN
cord-010499-yefxrj30	79	6	of	of	IN
cord-010499-yefxrj30	79	7	the	the	DT
cord-010499-yefxrj30	79	8	leftward	leftward	JJ
cord-010499-yefxrj30	79	9	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	79	10	frameshift	frameshift	NN
cord-010499-yefxrj30	79	11	is	be	VBZ
cord-010499-yefxrj30	79	12	the	the	DT
cord-010499-yefxrj30	79	13	successful	successful	JJ
cord-010499-yefxrj30	79	14	production	production	NN
cord-010499-yefxrj30	79	15	of	of	IN
cord-010499-yefxrj30	79	16	the	the	DT
cord-010499-yefxrj30	79	17	gag	gag	NN
cord-010499-yefxrj30	79	18	-	-	HYPH
cord-010499-yefxrj30	79	19	pol	pol	NN
cord-010499-yefxrj30	79	20	fusion	fusion	NN
cord-010499-yefxrj30	79	21	protein	protein	NN
cord-010499-yefxrj30	79	22	,	,	,
cord-010499-yefxrj30	79	23	in	in	IN
cord-010499-yefxrj30	79	24	the	the	DT
cord-010499-yefxrj30	79	25	assay	assay	NN
cord-010499-yefxrj30	79	26	system	system	NN
cord-010499-yefxrj30	79	27	we	-PRON-	PRP
cord-010499-yefxrj30	79	28	have	have	VBP
cord-010499-yefxrj30	79	29	devised	devise	VBN
cord-010499-yefxrj30	79	30	,	,	,
cord-010499-yefxrj30	80	1	the	the	DT
cord-010499-yefxrj30	80	2	outcome	outcome	NN
cord-010499-yefxrj30	80	3	of	of	IN
cord-010499-yefxrj30	80	4	an	an	DT
cord-010499-yefxrj30	80	5	analogous	analogous	JJ
cord-010499-yefxrj30	80	6	ieftward	ieftward	NN
cord-010499-yefxrj30	80	7	frameshift	frameshift	NN
cord-010499-yefxrj30	80	8	by	by	IN
cord-010499-yefxrj30	80	9	E	e	NN
cord-010499-yefxrj30	80	10	coli	coli	NNS
cord-010499-yefxrj30	80	11	ribosomes	ribosome	NNS
cord-010499-yefxrj30	80	12	wiii	wiii	NN
cord-010499-yefxrj30	80	13	be	be	VB
cord-010499-yefxrj30	80	14	the	the	DT
cord-010499-yefxrj30	80	15	successful	successful	JJ
cord-010499-yefxrj30	80	16	production	production	NN
cord-010499-yefxrj30	80	17	of	of	IN
cord-010499-yefxrj30	80	18	the	the	DT
cord-010499-yefxrj30	80	19	enzyme	enzyme	NN
cord-010499-yefxrj30	80	20	p	p	NN
cord-010499-yefxrj30	80	21	-	-	HYPH
cord-010499-yefxrj30	80	22	galactosidase	galactosidase	NN
cord-010499-yefxrj30	80	23	from	from	IN
cord-010499-yefxrj30	80	24	genetically	genetically	RB
cord-010499-yefxrj30	80	25	frameshifted	frameshifte	VBN
cord-010499-yefxrj30	80	26	alleles	allele	NNS
cord-010499-yefxrj30	80	27	of	of	IN
cord-010499-yefxrj30	80	28	the	the	DT
cord-010499-yefxrj30	80	29	/acZ	/acZ	NNP
cord-010499-yefxrj30	80	30	gene	gene	NN
cord-010499-yefxrj30	80	31	.	.	.
cord-010499-yefxrj30	81	1	We	-PRON-	PRP
cord-010499-yefxrj30	81	2	have	have	VBP
cord-010499-yefxrj30	81	3	previousiy	previousiy	NNP
cord-010499-yefxrj30	81	4	used	use	VBN
cord-010499-yefxrj30	81	5	an	an	DT
cord-010499-yefxrj30	81	6	assay	assay	NN
cord-010499-yefxrj30	81	7	system	system	NN
cord-010499-yefxrj30	81	8	of	of	IN
cord-010499-yefxrj30	81	9	similar	similar	JJ
cord-010499-yefxrj30	81	10	design	design	NN
cord-010499-yefxrj30	81	11	to	to	TO
cord-010499-yefxrj30	81	12	demonstrate	demonstrate	VB
cord-010499-yefxrj30	81	13	that	that	IN
cord-010499-yefxrj30	81	14	lysyl	lysyl	NN
cord-010499-yefxrj30	81	15	-	-	HYPH
cord-010499-yefxrj30	81	16	tRNA	trna	NN
cord-010499-yefxrj30	81	17	starvation	starvation	NN
cord-010499-yefxrj30	81	18	can	can	MD
cord-010499-yefxrj30	81	19	amplify	amplify	VB
cord-010499-yefxrj30	81	20	ribosomai	ribosomai	JJ
cord-010499-yefxrj30	81	21	frameshifting	frameshifting	NN
cord-010499-yefxrj30	81	22	in	in	IN
cord-010499-yefxrj30	81	23	either	either	DT
cord-010499-yefxrj30	81	24	direction	direction	NN
cord-010499-yefxrj30	81	25	at	at	IN
cord-010499-yefxrj30	81	26	iysine	iysine	NNP
cord-010499-yefxrj30	81	27	codons	codon	NNS
cord-010499-yefxrj30	81	28	,	,	,
cord-010499-yefxrj30	81	29	given	give	VBN
cord-010499-yefxrj30	81	30	certain	certain	JJ
cord-010499-yefxrj30	81	31	context	context	NN
cord-010499-yefxrj30	81	32	ruies	ruie	NNS
cord-010499-yefxrj30	81	33	(	(	-LRB-
cord-010499-yefxrj30	81	34	Gailant	Gailant	NNP
cord-010499-yefxrj30	81	35	and	and	CC
cord-010499-yefxrj30	81	36	Peter	Peter	NNP
cord-010499-yefxrj30	81	37	etai	etai	NNP
cord-010499-yefxrj30	81	38	.	.	.
cord-010499-yefxrj30	82	1	1992	1992	CD
cord-010499-yefxrj30	82	2	;	;	:
cord-010499-yefxrj30	82	3	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	82	4	and	and	CC
cord-010499-yefxrj30	82	5	Gailant	Gailant	NNP
cord-010499-yefxrj30	82	6	,	,	,
cord-010499-yefxrj30	82	7	1993	1993	CD
cord-010499-yefxrj30	82	8	)	)	-RRB-
cord-010499-yefxrj30	82	9	.	.	.
cord-010499-yefxrj30	83	1	Aileles	Aileles	NNP
cord-010499-yefxrj30	83	2	to	to	TO
cord-010499-yefxrj30	83	3	be	be	VB
cord-010499-yefxrj30	83	4	tested	test	VBN
cord-010499-yefxrj30	83	5	were	be	VBD
cord-010499-yefxrj30	83	6	constructed	construct	VBN
cord-010499-yefxrj30	83	7	by	by	IN
cord-010499-yefxrj30	83	8	the	the	DT
cord-010499-yefxrj30	83	9	ligatlon	ligatlon	NN
cord-010499-yefxrj30	83	10	of	of	IN
cord-010499-yefxrj30	83	11	paired	pair	VBN
cord-010499-yefxrj30	83	12	complementary	complementary	JJ
cord-010499-yefxrj30	83	13	oligonucleotides	oligonucleotide	NNS
cord-010499-yefxrj30	83	14	into	into	IN
cord-010499-yefxrj30	83	15	the	the	DT
cord-010499-yefxrj30	83	16	H	h	NN
cord-010499-yefxrj30	83	17	/	/	SYM
cord-010499-yefxrj30	83	18	ndlll	ndlll	NN
cord-010499-yefxrj30	83	19	-	-	HYPH
cord-010499-yefxrj30	83	20	BamH\	BamH\	NNS
cord-010499-yefxrj30	83	21	site	site	NN
cord-010499-yefxrj30	83	22	of	of	IN
cord-010499-yefxrj30	83	23	pBWHOO	pbwhoo	NN
cord-010499-yefxrj30	83	24	,	,	,
cord-010499-yefxrj30	83	25	as	as	IN
cord-010499-yefxrj30	83	26	described	describe	VBN
cord-010499-yefxrj30	83	27	in	in	IN
cord-010499-yefxrj30	83	28	Galiant	Galiant	NNP
cord-010499-yefxrj30	83	29	and	and	CC
cord-010499-yefxrj30	83	30	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	83	31	(	(	-LRB-
cord-010499-yefxrj30	83	32	1992	1992	CD
cord-010499-yefxrj30	83	33	)	)	-RRB-
cord-010499-yefxrj30	83	34	.	.	.
cord-010499-yefxrj30	84	1	Figure	figure	NN
cord-010499-yefxrj30	84	2	1	1	CD
cord-010499-yefxrj30	84	3	shows	show	VBZ
cord-010499-yefxrj30	84	4	the	the	DT
cord-010499-yefxrj30	84	5	sequence	sequence	NN
cord-010499-yefxrj30	84	6	of	of	IN
cord-010499-yefxrj30	84	7	the	the	DT
cord-010499-yefxrj30	84	8	translated	translate	VBN
cord-010499-yefxrj30	84	9	strand	strand	NN
cord-010499-yefxrj30	84	10	from	from	IN
cord-010499-yefxrj30	84	11	the	the	DT
cord-010499-yefxrj30	84	12	region	region	NN
cord-010499-yefxrj30	84	13	of	of	IN
cord-010499-yefxrj30	84	14	our	-PRON-	PRP$
cord-010499-yefxrj30	84	15	constructs	construct	NNS
cord-010499-yefxrj30	84	16	that	that	WDT
cord-010499-yefxrj30	84	17	reproduces	reproduce	VBZ
cord-010499-yefxrj30	84	18	the	the	DT
cord-010499-yefxrj30	84	19	gag	gag	NN
cord-010499-yefxrj30	84	20	-	-	HYPH
cord-010499-yefxrj30	84	21	pol	pol	NN
cord-010499-yefxrj30	84	22	frameshift	frameshift	NN
cord-010499-yefxrj30	84	23	signal	signal	NN
cord-010499-yefxrj30	84	24	from	from	IN
cord-010499-yefxrj30	84	25	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	84	26	.	.	.
cord-010499-yefxrj30	85	1	The	the	DT
cord-010499-yefxrj30	85	2	/acZ	/acZ	NNP
cord-010499-yefxrj30	85	3	frameshift	frameshift	NN
cord-010499-yefxrj30	85	4	alieles	aliele	NNS
cord-010499-yefxrj30	85	5	carried	carry	VBN
cord-010499-yefxrj30	85	6	on	on	IN
cord-010499-yefxrj30	85	7	plasmids	plasmid	NNS
cord-010499-yefxrj30	85	8	pi^iV13	pi^iV13	NNP
cord-010499-yefxrj30	85	9	and	and	CC
cord-010499-yefxrj30	85	10	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	85	11	are	be	VBP
cord-010499-yefxrj30	85	12	constructed	construct	VBN
cord-010499-yefxrj30	85	13	so	so	IN
cord-010499-yefxrj30	85	14	that	that	IN
cord-010499-yefxrj30	85	15	a	a	DT
cord-010499-yefxrj30	85	16	shift	shift	NN
cord-010499-yefxrj30	85	17	to	to	IN
cord-010499-yefxrj30	85	18	the	the	DT
cord-010499-yefxrj30	85	19	left	left	NN
cord-010499-yefxrj30	85	20	by	by	IN
cord-010499-yefxrj30	85	21	one	one	CD
cord-010499-yefxrj30	85	22	base	base	NN
cord-010499-yefxrj30	85	23	,	,	,
cord-010499-yefxrj30	85	24	as	as	IN
cord-010499-yefxrj30	85	25	in	in	IN
cord-010499-yefxrj30	85	26	the	the	DT
cord-010499-yefxrj30	85	27	expression	expression	NN
cord-010499-yefxrj30	85	28	of	of	IN
cord-010499-yefxrj30	85	29	the	the	DT
cord-010499-yefxrj30	85	30	gag	gag	NN
cord-010499-yefxrj30	85	31	-	-	HYPH
cord-010499-yefxrj30	85	32	po	po	NN
cord-010499-yefxrj30	85	33	/	/	SYM
cord-010499-yefxrj30	85	34	fusion	fusion	NN
cord-010499-yefxrj30	85	35	of	of	IN
cord-010499-yefxrj30	85	36	HIV	HIV	NNP
cord-010499-yefxrj30	85	37	,	,	,
cord-010499-yefxrj30	85	38	is	be	VBZ
cord-010499-yefxrj30	85	39	required	require	VBN
cord-010499-yefxrj30	85	40	to	to	TO
cord-010499-yefxrj30	85	41	generate	generate	VB
cord-010499-yefxrj30	85	42	active	active	JJ
cord-010499-yefxrj30	85	43	enzyme	enzyme	NN
cord-010499-yefxrj30	85	44	.	.	.
cord-010499-yefxrj30	86	1	The	the	DT
cord-010499-yefxrj30	86	2	two	two	CD
cord-010499-yefxrj30	86	3	constructs	construct	NNS
cord-010499-yefxrj30	86	4	both	both	DT
cord-010499-yefxrj30	86	5	carry	carry	VBP
cord-010499-yefxrj30	86	6	a	a	DT
cord-010499-yefxrj30	86	7	short	short	JJ
cord-010499-yefxrj30	86	8	sequence	sequence	NN
cord-010499-yefxrj30	86	9	identical	identical	JJ
cord-010499-yefxrj30	86	10	to	to	IN
cord-010499-yefxrj30	86	11	the	the	DT
cord-010499-yefxrj30	86	12	region	region	NN
cord-010499-yefxrj30	86	13	around	around	IN
cord-010499-yefxrj30	86	14	the	the	DT
cord-010499-yefxrj30	86	15	frameshift	frameshift	NN
cord-010499-yefxrj30	86	16	site	site	NN
cord-010499-yefxrj30	86	17	in	in	IN
cord-010499-yefxrj30	86	18	the	the	DT
cord-010499-yefxrj30	86	19	gag	gag	NN
cord-010499-yefxrj30	86	20	-	-	HYPH
cord-010499-yefxrj30	86	21	po	po	NN
cord-010499-yefxrj30	86	22	/	/	SYM
cord-010499-yefxrj30	86	23	overlap	overlap	NN
cord-010499-yefxrj30	86	24	of	of	IN
cord-010499-yefxrj30	86	25	HiV-1	HiV-1	NNP
cord-010499-yefxrj30	86	26	for	for	IN
cord-010499-yefxrj30	86	27	15	15	CD
cord-010499-yefxrj30	86	28	nucleotides	nucleotide	NNS
cord-010499-yefxrj30	86	29	in	in	IN
cord-010499-yefxrj30	86	30	pHIV13	pHIV13	NNP
cord-010499-yefxrj30	86	31	and	and	CC
cord-010499-yefxrj30	86	32	17	17	CD
cord-010499-yefxrj30	86	33	nucleotides	nucleotide	NNS
cord-010499-yefxrj30	86	34	in	in	IN
cord-010499-yefxrj30	86	35	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	87	1	(	(	-LRB-
cord-010499-yefxrj30	87	2	see	see	VB
cord-010499-yefxrj30	87	3	Fig	Fig	NNP
cord-010499-yefxrj30	87	4	.	.	NNP
cord-010499-yefxrj30	87	5	1	1	CD
cord-010499-yefxrj30	87	6	)	)	-RRB-
cord-010499-yefxrj30	87	7	;	;	:
cord-010499-yefxrj30	87	8	they	-PRON-	PRP
cord-010499-yefxrj30	87	9	differ	differ	VBP
cord-010499-yefxrj30	87	10	slightly	slightly	RB
cord-010499-yefxrj30	87	11	from	from	IN
cord-010499-yefxrj30	87	12	one	one	CD
cord-010499-yefxrj30	87	13	another	another	DT
cord-010499-yefxrj30	87	14	severai	severai	NN
cord-010499-yefxrj30	87	15	bases	basis	NNS
cord-010499-yefxrj30	87	16	downstream	downstream	RB
cord-010499-yefxrj30	87	17	of	of	IN
cord-010499-yefxrj30	87	18	the	the	DT
cord-010499-yefxrj30	87	19	frameshift	frameshift	NN
cord-010499-yefxrj30	87	20	site	site	NN
cord-010499-yefxrj30	87	21	.	.	.
cord-010499-yefxrj30	88	1	Host	host	NN
cord-010499-yefxrj30	88	2	ceils	ceil	NNS
cord-010499-yefxrj30	88	3	carrying	carry	VBG
cord-010499-yefxrj30	88	4	either	either	DT
cord-010499-yefxrj30	88	5	of	of	IN
cord-010499-yefxrj30	88	6	these	these	DT
cord-010499-yefxrj30	88	7	piasmids	piasmid	NNS
cord-010499-yefxrj30	88	8	produce	produce	VBP
cord-010499-yefxrj30	88	9	active	active	JJ
cord-010499-yefxrj30	88	10	enzyme	enzyme	NN
cord-010499-yefxrj30	88	11	at	at	IN
cord-010499-yefxrj30	88	12	about	about	RB
cord-010499-yefxrj30	88	13	1	1	CD
cord-010499-yefxrj30	88	14	%	%	NN
cord-010499-yefxrj30	88	15	of	of	IN
cord-010499-yefxrj30	88	16	the	the	DT
cord-010499-yefxrj30	88	17	efficiency	efficiency	NN
cord-010499-yefxrj30	88	18	of	of	IN
cord-010499-yefxrj30	88	19	cells	cell	NNS
cord-010499-yefxrj30	88	20	carrying	carry	VBG
cord-010499-yefxrj30	89	1	a	a	DT
cord-010499-yefxrj30	89	2	control	control	NN
cord-010499-yefxrj30	89	3	lacZ	lacZ	NNP
cord-010499-yefxrj30	89	4	*	*	NFP
cord-010499-yefxrj30	89	5	plasmid	plasmid	NN
cord-010499-yefxrj30	89	6	(	(	-LRB-
cord-010499-yefxrj30	89	7	Table	Table	NNP
cord-010499-yefxrj30	89	8	1	1	CD
cord-010499-yefxrj30	89	9	)	)	-RRB-
cord-010499-yefxrj30	89	10	.	.	.
cord-010499-yefxrj30	90	1	This	this	DT
cord-010499-yefxrj30	90	2	basal	basal	NN
cord-010499-yefxrj30	90	3	value	value	NN
cord-010499-yefxrj30	90	4	is	be	VBZ
cord-010499-yefxrj30	90	5	close	close	JJ
cord-010499-yefxrj30	90	6	to	to	IN
cord-010499-yefxrj30	90	7	the	the	DT
cord-010499-yefxrj30	90	8	value	value	NN
cord-010499-yefxrj30	90	9	(	(	-LRB-
cord-010499-yefxrj30	90	10	1.8	1.8	CD
cord-010499-yefxrj30	90	11	%	%	NN
cord-010499-yefxrj30	90	12	)	)	-RRB-
cord-010499-yefxrj30	90	13	observed	observe	VBN
cord-010499-yefxrj30	90	14	by	by	IN
cord-010499-yefxrj30	90	15	Weiss	Weiss	NNP
cord-010499-yefxrj30	90	16	et	et	NNP
cord-010499-yefxrj30	90	17	al	al	NNP
cord-010499-yefxrj30	90	18	.	.	.
cord-010499-yefxrj30	91	1	(	(	-LRB-
cord-010499-yefxrj30	91	2	1989	1989	CD
cord-010499-yefxrj30	91	3	)	)	-RRB-
cord-010499-yefxrj30	91	4	for	for	IN
cord-010499-yefxrj30	91	5	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	91	6	on	on	IN
cord-010499-yefxrj30	91	7	a	a	DT
cord-010499-yefxrj30	91	8	much	much	RB
cord-010499-yefxrj30	91	9	longer	long	JJR
cord-010499-yefxrj30	91	10	HIV	HIV	NNP
cord-010499-yefxrj30	91	11	-	-	HYPH
cord-010499-yefxrj30	91	12	derived	derive	VBN
cord-010499-yefxrj30	91	13	sequence	sequence	NN
cord-010499-yefxrj30	91	14	in	in	IN
cord-010499-yefxrj30	91	15	a	a	DT
cord-010499-yefxrj30	91	16	similar	similar	JJ
cord-010499-yefxrj30	91	17	p	p	NN
cord-010499-yefxrj30	91	18	-	-	HYPH
cord-010499-yefxrj30	91	19	galactosidase	galactosidase	NN
cord-010499-yefxrj30	91	20	reporter	reporter	NN
cord-010499-yefxrj30	91	21	.	.	.
cord-010499-yefxrj30	92	1	It	-PRON-	PRP
cord-010499-yefxrj30	92	2	is	be	VBZ
cord-010499-yefxrj30	92	3	also	also	RB
cord-010499-yefxrj30	92	4	much	much	RB
cord-010499-yefxrj30	92	5	higher	high	JJR
cord-010499-yefxrj30	92	6	than	than	IN
cord-010499-yefxrj30	92	7	the	the	DT
cord-010499-yefxrj30	92	8	frequency	frequency	NN
cord-010499-yefxrj30	92	9	of	of	IN
cord-010499-yefxrj30	92	10	leftward	leftward	JJ
cord-010499-yefxrj30	92	11	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	92	12	(	(	-LRB-
cord-010499-yefxrj30	92	13	0.03	0.03	CD
cord-010499-yefxrj30	92	14	-	-	SYM
cord-010499-yefxrj30	92	15	0.2	0.2	CD
cord-010499-yefxrj30	92	16	%	%	NN
cord-010499-yefxrj30	92	17	)	)	-RRB-
cord-010499-yefxrj30	93	1	we	-PRON-	PRP
cord-010499-yefxrj30	93	2	observed	observe	VBD
cord-010499-yefxrj30	93	3	previously	previously	RB
cord-010499-yefxrj30	93	4	at	at	IN
cord-010499-yefxrj30	93	5	sequences	sequence	NNS
cord-010499-yefxrj30	93	6	unrelated	unrelated	JJ
cord-010499-yefxrj30	93	7	to	to	IN
cord-010499-yefxrj30	93	8	HIV	HIV	NNP
cord-010499-yefxrj30	93	9	(	(	-LRB-
cord-010499-yefxrj30	93	10	Gailant	Gailant	NNP
cord-010499-yefxrj30	93	11	and	and	CC
cord-010499-yefxrj30	93	12	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	93	13	,	,	,
cord-010499-yefxrj30	93	14	1992	1992	CD
cord-010499-yefxrj30	93	15	)	)	-RRB-
cord-010499-yefxrj30	93	16	.	.	.
cord-010499-yefxrj30	94	1	The	the	DT
cord-010499-yefxrj30	94	2	presence	presence	NN
cord-010499-yefxrj30	94	3	of	of	IN
cord-010499-yefxrj30	94	4	the	the	DT
cord-010499-yefxrj30	94	5	HIV	HIV	NNP
cord-010499-yefxrj30	94	6	sequence	sequence	NN
cord-010499-yefxrj30	94	7	in	in	IN
cord-010499-yefxrj30	94	8	our	-PRON-	PRP$
cord-010499-yefxrj30	94	9	reporter	reporter	NN
cord-010499-yefxrj30	94	10	thus	thus	RB
cord-010499-yefxrj30	94	11	leads	lead	VBZ
cord-010499-yefxrj30	94	12	to	to	IN
cord-010499-yefxrj30	94	13	an	an	DT
cord-010499-yefxrj30	94	14	unusually	unusually	RB
cord-010499-yefxrj30	94	15	high	high	JJ
cord-010499-yefxrj30	94	16	frequency	frequency	NN
cord-010499-yefxrj30	94	17	of	of	IN
cord-010499-yefxrj30	94	18	leftward	leftward	JJ
cord-010499-yefxrj30	94	19	frameshifting	frameshifting	NN
cord-010499-yefxrj30	94	20	.	.	.
cord-010499-yefxrj30	95	1	Modification	modification	NN
cord-010499-yefxrj30	95	2	of	of	IN
cord-010499-yefxrj30	95	3	the	the	DT
cord-010499-yefxrj30	95	4	critical	critical	JJ
cord-010499-yefxrj30	95	5	heptanucieotide	heptanucieotide	NN
cord-010499-yefxrj30	95	6	sequence	sequence	NN
cord-010499-yefxrj30	95	7	from	from	IN
cord-010499-yefxrj30	95	8	U	U	NNP
cord-010499-yefxrj30	95	9	UUU	UUU	NNP
cord-010499-yefxrj30	95	10	UUA	UUA	NNP
cord-010499-yefxrj30	95	11	to	to	IN
cord-010499-yefxrj30	95	12	U	U	NNP
cord-010499-yefxrj30	95	13	UAU	UAU	NNP
cord-010499-yefxrj30	95	14	UUA	UUA	NNP
cord-010499-yefxrj30	95	15	in	in	IN
cord-010499-yefxrj30	95	16	plasmid	plasmid	NN
cord-010499-yefxrj30	95	17	pHIV13-A3	pHIV13-A3	NNP
cord-010499-yefxrj30	95	18	decreased	decrease	VBD
cord-010499-yefxrj30	95	19	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	95	20	about	about	IN
cord-010499-yefxrj30	95	21	fivefold	fivefold	NN
cord-010499-yefxrj30	95	22	,	,	,
cord-010499-yefxrj30	95	23	while	while	IN
cord-010499-yefxrj30	95	24	modification	modification	NN
cord-010499-yefxrj30	95	25	of	of	IN
cord-010499-yefxrj30	95	26	the	the	DT
cord-010499-yefxrj30	95	27	heptanucleotide	heptanucleotide	NN
cord-010499-yefxrj30	95	28	to	to	TO
cord-010499-yefxrj30	95	29	U	U	NNP
cord-010499-yefxrj30	95	30	UUU	UUU	NNP
cord-010499-yefxrj30	95	31	UUU	UUU	NNP
cord-010499-yefxrj30	95	32	in	in	IN
cord-010499-yefxrj30	95	33	pHIV201-U7	pHIV201-U7	NNP
cord-010499-yefxrj30	95	34	increased	increase	VBD
cord-010499-yefxrj30	95	35	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	95	36	by	by	IN
cord-010499-yefxrj30	95	37	two	two	CD
cord-010499-yefxrj30	95	38	-	-	HYPH
cord-010499-yefxrj30	95	39	to	to	IN
cord-010499-yefxrj30	95	40	threefold	threefold	VB
cord-010499-yefxrj30	95	41	(	(	-LRB-
cord-010499-yefxrj30	95	42	Tabie	Tabie	NNP
cord-010499-yefxrj30	95	43	1	1	CD
cord-010499-yefxrj30	95	44	)	)	-RRB-
cord-010499-yefxrj30	95	45	.	.	.
cord-010499-yefxrj30	96	1	These	these	DT
cord-010499-yefxrj30	96	2	genetic	genetic	JJ
cord-010499-yefxrj30	96	3	resuits	resuit	NNS
cord-010499-yefxrj30	96	4	are	be	VBP
cord-010499-yefxrj30	96	5	analagous	analagous	JJ
cord-010499-yefxrj30	96	6	to	to	IN
cord-010499-yefxrj30	96	7	earlier	early	JJR
cord-010499-yefxrj30	96	8	findings	finding	NNS
cord-010499-yefxrj30	96	9	in	in	IN
cord-010499-yefxrj30	96	10	other	other	JJ
cord-010499-yefxrj30	96	11	reporter	reporter	NN
cord-010499-yefxrj30	96	12	systems	system	NNS
cord-010499-yefxrj30	97	1	(	(	-LRB-
cord-010499-yefxrj30	97	2	Jaci	Jaci	NNP
cord-010499-yefxrj30	97	3	<	<	XX
cord-010499-yefxrj30	97	4	s	s	NNP
cord-010499-yefxrj30	97	5	et	et	FW
cord-010499-yefxrj30	97	6	ai	ai	NN
cord-010499-yefxrj30	97	7	.	.	.
cord-010499-yefxrj30	98	1	1988b	1988b	CD
cord-010499-yefxrj30	99	1	;	;	:
cord-010499-yefxrj30	99	2	Wilson	Wilson	NNP
cord-010499-yefxrj30	99	3	et	et	NNP
cord-010499-yefxrj30	99	4	ai	ai	NNP
cord-010499-yefxrj30	99	5	.	.	.
cord-010499-yefxrj30	100	1	1988	1988	CD
cord-010499-yefxrj30	100	2	;	;	:
cord-010499-yefxrj30	100	3	Weiss	Weiss	NNP
cord-010499-yefxrj30	100	4	et	et	NNP
cord-010499-yefxrj30	100	5	ai	ai	NNP
cord-010499-yefxrj30	100	6	,	,	,
cord-010499-yefxrj30	100	7	1989	1989	CD
cord-010499-yefxrj30	100	8	)	)	-RRB-
cord-010499-yefxrj30	100	9	and	and	CC
cord-010499-yefxrj30	100	10	suggest	suggest	VBP
cord-010499-yefxrj30	100	11	that	that	IN
cord-010499-yefxrj30	100	12	the	the	DT
cord-010499-yefxrj30	100	13	heptanucleotide	heptanucleotide	NN
cord-010499-yefxrj30	100	14	is	be	VBZ
cord-010499-yefxrj30	100	15	the	the	DT
cord-010499-yefxrj30	100	16	predominant	predominant	JJ
cord-010499-yefxrj30	100	17	site	site	NN
cord-010499-yefxrj30	100	18	of	of	IN
cord-010499-yefxrj30	100	19	leftward	leftward	JJ
cord-010499-yefxrj30	100	20	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	100	21	in	in	IN
cord-010499-yefxrj30	100	22	our	-PRON-	PRP$
cord-010499-yefxrj30	100	23	reporter	reporter	NN
cord-010499-yefxrj30	100	24	system	system	NN
cord-010499-yefxrj30	100	25	as	as	RB
cord-010499-yefxrj30	100	26	well	well	RB
cord-010499-yefxrj30	100	27	.	.	.
cord-010499-yefxrj30	101	1	Chemical	chemical	JJ
cord-010499-yefxrj30	101	2	evidence	evidence	NN
cord-010499-yefxrj30	101	3	that	that	IN
cord-010499-yefxrj30	101	4	this	this	DT
cord-010499-yefxrj30	101	5	is	be	VBZ
cord-010499-yefxrj30	101	6	indeed	indeed	RB
cord-010499-yefxrj30	101	7	the	the	DT
cord-010499-yefxrj30	101	8	case	case	NN
cord-010499-yefxrj30	101	9	was	be	VBD
cord-010499-yefxrj30	101	10	obtained	obtain	VBN
cord-010499-yefxrj30	101	11	from	from	IN
cord-010499-yefxrj30	101	12	protein	protein	NN
cord-010499-yefxrj30	101	13	sequence	sequence	NN
cord-010499-yefxrj30	101	14	analysis	analysis	NN
cord-010499-yefxrj30	101	15	.	.	.
cord-010499-yefxrj30	102	1	The	the	DT
cord-010499-yefxrj30	102	2	protein	protein	NN
cord-010499-yefxrj30	102	3	encoded	encode	VBN
cord-010499-yefxrj30	102	4	by	by	IN
cord-010499-yefxrj30	102	5	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	102	6	was	be	VBD
cord-010499-yefxrj30	102	7	purified	purify	VBN
cord-010499-yefxrj30	102	8	and	and	CC
cord-010499-yefxrj30	102	9	subjected	subject	VBN
cord-010499-yefxrj30	102	10	to	to	IN
cord-010499-yefxrj30	102	11	automated	automate	VBN
cord-010499-yefxrj30	102	12	Edman	Edman	NNP
cord-010499-yefxrj30	102	13	sequence	sequence	NN
cord-010499-yefxrj30	102	14	analysis	analysis	NN
cord-010499-yefxrj30	102	15	,	,	,
cord-010499-yefxrj30	102	16	as	as	IN
cord-010499-yefxrj30	102	17	previously	previously	RB
cord-010499-yefxrj30	102	18	described	describe	VBN
cord-010499-yefxrj30	102	19	Peter	Peter	NNP
cord-010499-yefxrj30	102	20	et	et	NNP
cord-010499-yefxrj30	102	21	al	al	NNP
cord-010499-yefxrj30	102	22	.	.	NNP
cord-010499-yefxrj30	102	23	,	,	,
cord-010499-yefxrj30	102	24	1992	1992	CD
cord-010499-yefxrj30	102	25	)	)	-RRB-
cord-010499-yefxrj30	102	26	.	.	.
cord-010499-yefxrj30	103	1	The	the	DT
cord-010499-yefxrj30	103	2	results	result	NNS
cord-010499-yefxrj30	103	3	(	(	-LRB-
cord-010499-yefxrj30	103	4	Fig	fig	NN
cord-010499-yefxrj30	103	5	.	.	NNP
cord-010499-yefxrj30	103	6	2	2	LS
cord-010499-yefxrj30	103	7	)	)	-RRB-
cord-010499-yefxrj30	103	8	are	be	VBP
cord-010499-yefxrj30	103	9	readily	readily	RB
cord-010499-yefxrj30	103	10	interpreted	interpret	VBN
cord-010499-yefxrj30	103	11	with	with	IN
cord-010499-yefxrj30	103	12	reference	reference	NN
cord-010499-yefxrj30	103	13	to	to	IN
cord-010499-yefxrj30	103	14	the	the	DT
cord-010499-yefxrj30	103	15	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	103	16	sequence	sequence	NN
cord-010499-yefxrj30	103	17	and	and	CC
cord-010499-yefxrj30	103	18	coding	code	VBG
cord-010499-yefxrj30	103	19	potential	potential	JJ
cord-010499-yefxrj30	103	20	shown	show	VBN
cord-010499-yefxrj30	103	21	in	in	IN
cord-010499-yefxrj30	103	22	Fig	Fig	NNP
cord-010499-yefxrj30	103	23	.	.	.
cord-010499-yefxrj30	104	1	1	1	LS
cord-010499-yefxrj30	104	2	.	.	.
cord-010499-yefxrj30	105	1	For	for	IN
cord-010499-yefxrj30	105	2	the	the	DT
cord-010499-yefxrj30	105	3	first	first	JJ
cord-010499-yefxrj30	105	4	10	10	CD
cord-010499-yefxrj30	105	5	cycles	cycle	NNS
cord-010499-yefxrj30	105	6	,	,	,
cord-010499-yefxrj30	105	7	the	the	DT
cord-010499-yefxrj30	105	8	amino	amino	NN
cord-010499-yefxrj30	105	9	acid	acid	NN
cord-010499-yefxrj30	105	10	sequence	sequence	NN
cord-010499-yefxrj30	105	11	corresponds	correspond	VBZ
cord-010499-yefxrj30	105	12	to	to	IN
cord-010499-yefxrj30	105	13	normal	normal	JJ
cord-010499-yefxrj30	105	14	transiation	transiation	NN
cord-010499-yefxrj30	105	15	in	in	IN
cord-010499-yefxrj30	105	16	the	the	DT
cord-010499-yefxrj30	105	17	(	(	-LRB-
cord-010499-yefxrj30	105	18	0	0	NFP
cord-010499-yefxrj30	105	19	)	)	-RRB-
cord-010499-yefxrj30	105	20	reading	reading	NN
cord-010499-yefxrj30	105	21	frame	frame	NN
cord-010499-yefxrj30	105	22	:	:	:
cord-010499-yefxrj30	105	23	T	T	NNP
cord-010499-yefxrj30	105	24	-	-	HYPH
cord-010499-yefxrj30	105	25	M	M	NNP
cord-010499-yefxrj30	105	26	-	-	HYPH
cord-010499-yefxrj30	105	27	i	i	NNP
cord-010499-yefxrj30	105	28	-	-	HYPH
cord-010499-yefxrj30	105	29	T	T	NNP
cord-010499-yefxrj30	105	30	-	-	HYPH
cord-010499-yefxrj30	105	31	P	P	NNP
cord-010499-yefxrj30	105	32	-	-	HYPH
cord-010499-yefxrj30	105	33	S	S	NNP
cord-010499-yefxrj30	105	34	-	-	HYPH
cord-010499-yefxrj30	105	35	S	S	NNP
cord-010499-yefxrj30	105	36	-	-	HYPH
cord-010499-yefxrj30	105	37	N	N	NNP
cord-010499-yefxrj30	105	38	-	-	HYPH
cord-010499-yefxrj30	105	39	F	F	NNP
cord-010499-yefxrj30	105	40	-	-	HYPH
cord-010499-yefxrj30	105	41	L.	L.	NNP
cord-010499-yefxrj30	106	1	After	after	IN
cord-010499-yefxrj30	106	2	this	this	DT
cord-010499-yefxrj30	106	3	position	position	NN
cord-010499-yefxrj30	106	4	,	,	,
cord-010499-yefxrj30	106	5	the	the	DT
cord-010499-yefxrj30	106	6	signal	signal	NN
cord-010499-yefxrj30	106	7	(	(	-LRB-
cord-010499-yefxrj30	106	8	R	r	NN
cord-010499-yefxrj30	106	9	-	-	HYPH
cord-010499-yefxrj30	106	10	E	e	NN
cord-010499-yefxrj30	106	11	-	-	HYPH
cord-010499-yefxrj30	106	12	G	g	NN
cord-010499-yefxrj30	106	13	-	-	HYPH
cord-010499-yefxrj30	106	14	l	l	NN
cord-010499-yefxrj30	106	15	-	-	HYPH
cord-010499-yefxrj30	106	16	P	P	NNP
cord-010499-yefxrj30	106	17	)	)	-RRB-
cord-010499-yefxrj30	106	18	clearly	clearly	RB
cord-010499-yefxrj30	106	19	corresponds	correspond	VBZ
cord-010499-yefxrj30	106	20	to	to	IN
cord-010499-yefxrj30	106	21	the	the	DT
cord-010499-yefxrj30	106	22	leftward	leftward	JJ
cord-010499-yefxrj30	106	23	reading	reading	NN
cord-010499-yefxrj30	106	24	frame	frame	NN
cord-010499-yefxrj30	106	25	.	.	.
cord-010499-yefxrj30	107	1	Thus	thus	RB
cord-010499-yefxrj30	107	2	,	,	,
cord-010499-yefxrj30	107	3	a	a	DT
cord-010499-yefxrj30	107	4	leftward	leftward	JJ
cord-010499-yefxrj30	107	5	shift	shift	NN
cord-010499-yefxrj30	107	6	occurred	occur	VBD
cord-010499-yefxrj30	107	7	after	after	IN
cord-010499-yefxrj30	107	8	incorporation	incorporation	NN
cord-010499-yefxrj30	107	9	of	of	IN
cord-010499-yefxrj30	107	10	the	the	DT
cord-010499-yefxrj30	107	11	leucine	leucine	NN
cord-010499-yefxrj30	107	12	at	at	IN
cord-010499-yefxrj30	107	13	position	position	NN
cord-010499-yefxrj30	107	14	10	10	CD
cord-010499-yefxrj30	107	15	,	,	,
cord-010499-yefxrj30	107	16	exactly	exactly	RB
cord-010499-yefxrj30	107	17	the	the	DT
cord-010499-yefxrj30	107	18	frameshift	frameshift	NN
cord-010499-yefxrj30	107	19	cfiaracteristic	cfiaracteristic	NN
cord-010499-yefxrj30	107	20	of	of	IN
cord-010499-yefxrj30	107	21	HIV	HIV	NNP
cord-010499-yefxrj30	107	22	translation	translation	NN
cord-010499-yefxrj30	107	23	in	in	IN
cord-010499-yefxrj30	107	24	eukaryotic	eukaryotic	JJ
cord-010499-yefxrj30	107	25	systems	system	NNS
cord-010499-yefxrj30	108	1	(	(	-LRB-
cord-010499-yefxrj30	108	2	Jacks	Jacks	NNP
cord-010499-yefxrj30	108	3	et	et	NNP
cord-010499-yefxrj30	108	4	ai	ai	NN
cord-010499-yefxrj30	108	5	,	,	,
cord-010499-yefxrj30	108	6	1988b	1988b	CD
cord-010499-yefxrj30	108	7	)	)	-RRB-
cord-010499-yefxrj30	108	8	.	.	.
cord-010499-yefxrj30	109	1	Similar	similar	JJ
cord-010499-yefxrj30	109	2	resuits	resuit	NNS
cord-010499-yefxrj30	109	3	were	be	VBD
cord-010499-yefxrj30	109	4	obtained	obtain	VBN
cord-010499-yefxrj30	109	5	with	with	IN
cord-010499-yefxrj30	109	6	plasmid	plasmid	NN
cord-010499-yefxrj30	109	7	pHiV13	pHiV13	NNP
cord-010499-yefxrj30	109	8	(	(	-LRB-
cord-010499-yefxrj30	109	9	data	datum	NNS
cord-010499-yefxrj30	109	10	not	not	RB
cord-010499-yefxrj30	109	11	shown	show	VBN
cord-010499-yefxrj30	109	12	)	)	-RRB-
cord-010499-yefxrj30	109	13	.	.	.
cord-010499-yefxrj30	110	1	Thus	thus	RB
cord-010499-yefxrj30	110	2	,	,	,
cord-010499-yefxrj30	110	3	our	-PRON-	PRP$
cord-010499-yefxrj30	110	4	short	short	JJ
cord-010499-yefxrj30	110	5	cloned	clone	VBN
cord-010499-yefxrj30	110	6	sequence	sequence	NN
cord-010499-yefxrj30	110	7	reproduces	reproduce	VBZ
cord-010499-yefxrj30	110	8	the	the	DT
cord-010499-yefxrj30	110	9	specificity	specificity	NN
cord-010499-yefxrj30	110	10	of	of	IN
cord-010499-yefxrj30	110	11	the	the	DT
cord-010499-yefxrj30	110	12	HIV	HIV	NNP
cord-010499-yefxrj30	110	13	frameshift	frameshift	NN
cord-010499-yefxrj30	110	14	signal	signal	NN
cord-010499-yefxrj30	110	15	when	when	WRB
cord-010499-yefxrj30	110	16	translated	translate	VBN
cord-010499-yefxrj30	110	17	by	by	IN
cord-010499-yefxrj30	110	18	E.	E.	NNP
cord-010499-yefxrj30	110	19	coli	coli	NNS
cord-010499-yefxrj30	110	20	ribosomes	ribosome	NNS
cord-010499-yefxrj30	110	21	.	.	.
cord-010499-yefxrj30	111	1	We	-PRON-	PRP
cord-010499-yefxrj30	111	2	asked	ask	VBD
cord-010499-yefxrj30	111	3	whether	whether	IN
cord-010499-yefxrj30	111	4	the	the	DT
cord-010499-yefxrj30	111	5	HIV	HIV	NNP
cord-010499-yefxrj30	111	6	sequence	sequence	NN
cord-010499-yefxrj30	111	7	's	's	POS
cord-010499-yefxrj30	111	8	rather	rather	RB
cord-010499-yefxrj30	111	9	high	high	JJ
cord-010499-yefxrj30	111	10	level	level	NN
cord-010499-yefxrj30	111	11	of	of	IN
cord-010499-yefxrj30	111	12	shiftiness	shiftiness	NN
cord-010499-yefxrj30	111	13	could	could	MD
cord-010499-yefxrj30	111	14	be	be	VB
cord-010499-yefxrj30	111	15	modulated	modulate	VBN
cord-010499-yefxrj30	111	16	by	by	IN
cord-010499-yefxrj30	111	17	stalling	stall	VBG
cord-010499-yefxrj30	111	18	the	the	DT
cord-010499-yefxrj30	111	19	ribosome	ribosome	NN
cord-010499-yefxrj30	111	20	at	at	IN
cord-010499-yefxrj30	111	21	hungry	hungry	JJ
cord-010499-yefxrj30	111	22	codons	codon	NNS
cord-010499-yefxrj30	111	23	within	within	IN
cord-010499-yefxrj30	111	24	the	the	DT
cord-010499-yefxrj30	111	25	frameshift	frameshift	NN
cord-010499-yefxrj30	111	26	region	region	NN
cord-010499-yefxrj30	111	27	.	.	.
cord-010499-yefxrj30	112	1	Phe	Phe	NNP
cord-010499-yefxrj30	112	2	and	and	CC
cord-010499-yefxrj30	112	3	ieu	ieu	NNP
cord-010499-yefxrj30	112	4	are	be	VBP
cord-010499-yefxrj30	112	5	the	the	DT
cord-010499-yefxrj30	112	6	last	last	JJ
cord-010499-yefxrj30	112	7	two	two	CD
cord-010499-yefxrj30	112	8	amino	amino	NN
cord-010499-yefxrj30	112	9	acids	acid	NNS
cord-010499-yefxrj30	112	10	encoded	encode	VBN
cord-010499-yefxrj30	112	11	in	in	IN
cord-010499-yefxrj30	112	12	the	the	DT
cord-010499-yefxrj30	112	13	initial	initial	JJ
cord-010499-yefxrj30	112	14	reading	reading	NN
cord-010499-yefxrj30	112	15	frame	frame	NN
cord-010499-yefxrj30	112	16	before	before	IN
cord-010499-yefxrj30	112	17	the	the	DT
cord-010499-yefxrj30	112	18	shift	shift	NN
cord-010499-yefxrj30	112	19	,	,	,
cord-010499-yefxrj30	112	20	and	and	CC
cord-010499-yefxrj30	112	21	Arg	arg	NN
cord-010499-yefxrj30	112	22	is	be	VBZ
cord-010499-yefxrj30	112	23	the	the	DT
cord-010499-yefxrj30	112	24	first	first	RB
cord-010499-yefxrj30	112	25	encoded	encode	VBN
cord-010499-yefxrj30	112	26	in	in	IN
cord-010499-yefxrj30	112	27	the	the	DT
cord-010499-yefxrj30	112	28	new	new	JJ
cord-010499-yefxrj30	112	29	reading	reading	NN
cord-010499-yefxrj30	112	30	frame	frame	NN
cord-010499-yefxrj30	112	31	after	after	IN
cord-010499-yefxrj30	112	32	the	the	DT
cord-010499-yefxrj30	112	33	shift	shift	NN
cord-010499-yefxrj30	112	34	.	.	.
cord-010499-yefxrj30	113	1	We	-PRON-	PRP
cord-010499-yefxrj30	113	2	imposed	impose	VBD
cord-010499-yefxrj30	113	3	iimitation	iimitation	NN
cord-010499-yefxrj30	113	4	for	for	IN
cord-010499-yefxrj30	113	5	phe	phe	NN
cord-010499-yefxrj30	113	6	-	-	HYPH
cord-010499-yefxrj30	113	7	tHNA	thna	JJ
cord-010499-yefxrj30	113	8	by	by	IN
cord-010499-yefxrj30	113	9	inhibiting	inhibit	VBG
cord-010499-yefxrj30	113	10	the	the	DT
cord-010499-yefxrj30	113	11	synthetase	synthetase	NN
cord-010499-yefxrj30	113	12	with	with	IN
cord-010499-yefxrj30	113	13	the	the	DT
cord-010499-yefxrj30	113	14	analogue	analogue	JJ
cord-010499-yefxrj30	113	15	phenylaianine	phenylaianine	NN
cord-010499-yefxrj30	113	16	-	-	HYPH
cord-010499-yefxrj30	113	17	hydroxamate	hydroxamate	NN
cord-010499-yefxrj30	113	18	(	(	-LRB-
cord-010499-yefxrj30	113	19	PHX	PHX	NNP
cord-010499-yefxrj30	113	20	)	)	-RRB-
cord-010499-yefxrj30	113	21	.	.	.
cord-010499-yefxrj30	114	1	Graded	grade	VBN
cord-010499-yefxrj30	114	2	limitations	limitation	NNS
cord-010499-yefxrj30	114	3	for	for	IN
cord-010499-yefxrj30	114	4	arginine	arginine	NN
cord-010499-yefxrj30	114	5	or	or	CC
cord-010499-yefxrj30	114	6	ieucine	ieucine	NN
cord-010499-yefxrj30	114	7	were	be	VBD
cord-010499-yefxrj30	114	8	imposed	impose	VBN
cord-010499-yefxrj30	114	9	by	by	IN
cord-010499-yefxrj30	114	10	growing	grow	VBG
cord-010499-yefxrj30	114	11	auxotrophic	auxotrophic	JJ
cord-010499-yefxrj30	114	12	host	host	NN
cord-010499-yefxrj30	114	13	cells	cell	NNS
cord-010499-yefxrj30	114	14	on	on	IN
cord-010499-yefxrj30	114	15	a	a	DT
cord-010499-yefxrj30	114	16	range	range	NN
cord-010499-yefxrj30	114	17	of	of	IN
cord-010499-yefxrj30	114	18	concentrations	concentration	NNS
cord-010499-yefxrj30	114	19	of	of	IN
cord-010499-yefxrj30	114	20	slowiy	slowiy	JJ
cord-010499-yefxrj30	114	21	utiiized	utiiized	JJ
cord-010499-yefxrj30	114	22	methyl	methyl	NN
cord-010499-yefxrj30	114	23	esters	ester	NNS
cord-010499-yefxrj30	114	24	of	of	IN
cord-010499-yefxrj30	114	25	these	these	DT
cord-010499-yefxrj30	114	26	amino	amino	NN
cord-010499-yefxrj30	114	27	acids	acid	NNS
cord-010499-yefxrj30	114	28	(	(	-LRB-
cord-010499-yefxrj30	114	29	Buston	Buston	NNP
cord-010499-yefxrj30	114	30	and	and	CC
cord-010499-yefxrj30	114	31	Bishop	Bishop	NNP
cord-010499-yefxrj30	114	32	,	,	,
cord-010499-yefxrj30	114	33	1955	1955	CD
cord-010499-yefxrj30	114	34	)	)	-RRB-
cord-010499-yefxrj30	114	35	.	.	.
cord-010499-yefxrj30	115	1	Tables	table	NNS
cord-010499-yefxrj30	115	2	2	2	CD
cord-010499-yefxrj30	115	3	and	and	CC
cord-010499-yefxrj30	115	4	3	3	CD
cord-010499-yefxrj30	115	5	present	present	VBP
cord-010499-yefxrj30	115	6	the	the	DT
cord-010499-yefxrj30	115	7	results	result	NNS
cord-010499-yefxrj30	115	8	of	of	IN
cord-010499-yefxrj30	115	9	ali	ali	NNP
cord-010499-yefxrj30	115	10	these	these	DT
cord-010499-yefxrj30	115	11	limitation	limitation	NN
cord-010499-yefxrj30	115	12	regimens	regimen	NNS
cord-010499-yefxrj30	115	13	.	.	.
cord-010499-yefxrj30	116	1	Considering	consider	VBG
cord-010499-yefxrj30	116	2	first	first	JJ
cord-010499-yefxrj30	116	3	Arg	arg	NN
cord-010499-yefxrj30	116	4	and	and	CC
cord-010499-yefxrj30	116	5	Phe	Phe	NNP
cord-010499-yefxrj30	116	6	(	(	-LRB-
cord-010499-yefxrj30	116	7	Table	Table	NNP
cord-010499-yefxrj30	116	8	2	2	CD
cord-010499-yefxrj30	116	9	)	)	-RRB-
cord-010499-yefxrj30	116	10	,	,	,
cord-010499-yefxrj30	116	11	we	-PRON-	PRP
cord-010499-yefxrj30	116	12	observe	observe	VBP
cord-010499-yefxrj30	116	13	that	that	IN
cord-010499-yefxrj30	116	14	both	both	DT
cord-010499-yefxrj30	116	15	limitations	limitation	NNS
cord-010499-yefxrj30	116	16	substantiaily	substantiaily	RB
cord-010499-yefxrj30	116	17	reduced	reduce	VBD
cord-010499-yefxrj30	116	18	the	the	DT
cord-010499-yefxrj30	116	19	differential	differential	JJ
cord-010499-yefxrj30	116	20	rate	rate	NN
cord-010499-yefxrj30	116	21	of	of	IN
cord-010499-yefxrj30	116	22	enzyme	enzyme	NN
cord-010499-yefxrj30	116	23	synthesis	synthesis	NN
cord-010499-yefxrj30	116	24	expressed	express	VBN
cord-010499-yefxrj30	116	25	from	from	IN
cord-010499-yefxrj30	116	26	both	both	CC
cord-010499-yefxrj30	116	27	the	the	DT
cord-010499-yefxrj30	116	28	frameshift	frameshift	NN
cord-010499-yefxrj30	116	29	construct	construct	NN
cord-010499-yefxrj30	116	30	and	and	CC
cord-010499-yefxrj30	116	31	the	the	DT
cord-010499-yefxrj30	116	32	lacZ	lacZ	NNS
cord-010499-yefxrj30	117	1	*	*	NFP
cord-010499-yefxrj30	117	2	control	control	NN
cord-010499-yefxrj30	117	3	.	.	.
cord-010499-yefxrj30	118	1	The	the	DT
cord-010499-yefxrj30	118	2	reduction	reduction	NN
cord-010499-yefxrj30	118	3	was	be	VBD
cord-010499-yefxrj30	118	4	about	about	IN
cord-010499-yefxrj30	118	5	the	the	DT
cord-010499-yefxrj30	118	6	same	same	JJ
cord-010499-yefxrj30	118	7	in	in	IN
cord-010499-yefxrj30	118	8	both	both	DT
cord-010499-yefxrj30	118	9	genotypes	genotype	NNS
cord-010499-yefxrj30	118	10	,	,	,
cord-010499-yefxrj30	118	11	indicating	indicate	VBG
cord-010499-yefxrj30	118	12	that	that	IN
cord-010499-yefxrj30	118	13	neither	neither	CC
cord-010499-yefxrj30	118	14	arginine	arginine	NN
cord-010499-yefxrj30	118	15	limitation	limitation	NN
cord-010499-yefxrj30	118	16	nor	nor	CC
cord-010499-yefxrj30	118	17	phe	phe	NN
cord-010499-yefxrj30	118	18	-	-	HYPH
cord-010499-yefxrj30	118	19	tRNA	trna	JJ
cord-010499-yefxrj30	118	20	limitation	limitation	NN
cord-010499-yefxrj30	118	21	had	have	VBD
cord-010499-yefxrj30	118	22	a	a	DT
cord-010499-yefxrj30	118	23	specific	specific	JJ
cord-010499-yefxrj30	118	24	effect	effect	NN
cord-010499-yefxrj30	118	25	on	on	IN
cord-010499-yefxrj30	118	26	the	the	DT
cord-010499-yefxrj30	118	27	frequency	frequency	NN
cord-010499-yefxrj30	118	28	of	of	IN
cord-010499-yefxrj30	118	29	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	118	30	within	within	IN
cord-010499-yefxrj30	118	31	the	the	DT
cord-010499-yefxrj30	118	32	HIV	HIV	NNP
cord-010499-yefxrj30	118	33	sequence	sequence	NN
cord-010499-yefxrj30	118	34	.	.	.
cord-010499-yefxrj30	119	1	In	in	IN
cord-010499-yefxrj30	119	2	order	order	NN
cord-010499-yefxrj30	119	3	to	to	TO
cord-010499-yefxrj30	119	4	ensure	ensure	VB
cord-010499-yefxrj30	119	5	leucine	leucine	JJ
cord-010499-yefxrj30	119	6	sufficiency	sufficiency	NN
cord-010499-yefxrj30	119	7	,	,	,
cord-010499-yefxrj30	119	8	the	the	DT
cord-010499-yefxrj30	119	9	host	host	NN
cord-010499-yefxrj30	119	10	was	be	VBD
cord-010499-yefxrj30	119	11	a	a	DT
cord-010499-yefxrj30	119	12	ieucine	ieucine	JJ
cord-010499-yefxrj30	119	13	prototroph	prototroph	NNS
cord-010499-yefxrj30	119	14	isogenic	isogenic	JJ
cord-010499-yefxrj30	119	15	with	with	IN
cord-010499-yefxrj30	119	16	our	-PRON-	PRP$
cord-010499-yefxrj30	119	17	normal	normal	JJ
cord-010499-yefxrj30	119	18	host	host	NN
cord-010499-yefxrj30	119	19	,	,	,
cord-010499-yefxrj30	119	20	and	and	CC
cord-010499-yefxrj30	119	21	it	-PRON-	PRP
cord-010499-yefxrj30	119	22	was	be	VBD
cord-010499-yefxrj30	119	23	grown	grow	VBN
cord-010499-yefxrj30	119	24	nevertheless	nevertheless	RB
cord-010499-yefxrj30	119	25	in	in	IN
cord-010499-yefxrj30	119	26	the	the	DT
cord-010499-yefxrj30	119	27	presence	presence	NN
cord-010499-yefxrj30	119	28	of	of	IN
cord-010499-yefxrj30	119	29	100	100	CD
cord-010499-yefxrj30	119	30	jig	jig	NN
cord-010499-yefxrj30	119	31	ml	ml	NNS
cord-010499-yefxrj30	119	32	"	"	''
cord-010499-yefxrj30	119	33	^	^	.
cord-010499-yefxrj30	119	34	leucine	leucine	NN
cord-010499-yefxrj30	119	35	.	.	.
cord-010499-yefxrj30	120	1	The	the	DT
cord-010499-yefxrj30	120	2	/ac	/ac	CD
cord-010499-yefxrj30	120	3	promoter	promoter	NN
cord-010499-yefxrj30	120	4	was	be	VBD
cord-010499-yefxrj30	120	5	induced	induce	VBN
cord-010499-yefxrj30	120	6	for	for	IN
cord-010499-yefxrj30	120	7	one	one	CD
cord-010499-yefxrj30	120	8	doubling	double	VBG
cord-010499-yefxrj30	120	9	and	and	CC
cord-010499-yefxrj30	120	10	two	two	CD
cord-010499-yefxrj30	120	11	litres	litre	NNS
cord-010499-yefxrj30	120	12	of	of	IN
cord-010499-yefxrj30	120	13	cells	cell	NNS
cord-010499-yefxrj30	120	14	were	be	VBD
cord-010499-yefxrj30	120	15	harvested	harvest	VBN
cord-010499-yefxrj30	120	16	.	.	.
cord-010499-yefxrj30	121	1	Beta	beta	JJ
cord-010499-yefxrj30	121	2	-	-	HYPH
cord-010499-yefxrj30	121	3	galactosidase	galactosidase	NN
cord-010499-yefxrj30	121	4	was	be	VBD
cord-010499-yefxrj30	121	5	isolated	isolate	VBN
cord-010499-yefxrj30	121	6	as	as	IN
cord-010499-yefxrj30	121	7	described	describe	VBN
cord-010499-yefxrj30	121	8	previously	previously	RB
cord-010499-yefxrj30	121	9	Peter	Peter	NNP
cord-010499-yefxrj30	121	10	ef	ef	NNP
cord-010499-yefxrj30	121	11	ai	ai	NNP
cord-010499-yefxrj30	121	12	.	.	.
cord-010499-yefxrj30	121	13	1992	1992	CD
cord-010499-yefxrj30	121	14	)	)	-RRB-
cord-010499-yefxrj30	121	15	and	and	CC
cord-010499-yefxrj30	121	16	subjected	subject	VBN
cord-010499-yefxrj30	121	17	to	to	IN
cord-010499-yefxrj30	121	18	automated	automate	VBN
cord-010499-yefxrj30	121	19	Edman	Edman	NNP
cord-010499-yefxrj30	121	20	sequencing	sequencing	NN
cord-010499-yefxrj30	121	21	.	.	.
cord-010499-yefxrj30	122	1	The	the	DT
cord-010499-yefxrj30	122	2	raw	raw	JJ
cord-010499-yefxrj30	122	3	data	datum	NNS
cord-010499-yefxrj30	122	4	for	for	IN
cord-010499-yefxrj30	122	5	picomole	picomole	NN
cord-010499-yefxrj30	122	6	amounts	amount	NNS
cord-010499-yefxrj30	122	7	of	of	IN
cord-010499-yefxrj30	122	8	PTH	PTH	NNP
cord-010499-yefxrj30	122	9	amino	amino	NN
cord-010499-yefxrj30	122	10	acids	acid	NNS
cord-010499-yefxrj30	122	11	in	in	IN
cord-010499-yefxrj30	122	12	each	each	DT
cord-010499-yefxrj30	122	13	cycle	cycle	NN
cord-010499-yefxrj30	122	14	were	be	VBD
cord-010499-yefxrj30	122	15	corrected	correct	VBN
cord-010499-yefxrj30	122	16	for	for	IN
cord-010499-yefxrj30	122	17	background	background	NN
cord-010499-yefxrj30	122	18	and	and	CC
cord-010499-yefxrj30	122	19	lag	lag	VB
cord-010499-yefxrj30	122	20	using	use	VBG
cord-010499-yefxrj30	122	21	Applied	Applied	NNP
cord-010499-yefxrj30	122	22	Biosystems	Biosystems	NNP
cord-010499-yefxrj30	122	23	software	software	NN
cord-010499-yefxrj30	122	24	,	,	,
cord-010499-yefxrj30	122	25	as	as	IN
cord-010499-yefxrj30	122	26	described	describe	VBN
cord-010499-yefxrj30	122	27	.	.	.
cord-010499-yefxrj30	123	1	The	the	DT
cord-010499-yefxrj30	123	2	figure	figure	NN
cord-010499-yefxrj30	123	3	presents	present	VBZ
cord-010499-yefxrj30	123	4	the	the	DT
cord-010499-yefxrj30	123	5	sum	sum	NN
cord-010499-yefxrj30	123	6	of	of	IN
cord-010499-yefxrj30	123	7	three	three	CD
cord-010499-yefxrj30	123	8	independent	independent	JJ
cord-010499-yefxrj30	123	9	sequencing	sequencing	NN
cord-010499-yefxrj30	123	10	runs	run	NNS
cord-010499-yefxrj30	123	11	,	,	,
cord-010499-yefxrj30	123	12	one	one	CD
cord-010499-yefxrj30	123	13	performed	perform	VBN
cord-010499-yefxrj30	123	14	at	at	IN
cord-010499-yefxrj30	123	15	Illinois	Illinois	NNP
cord-010499-yefxrj30	123	16	and	and	CC
cord-010499-yefxrj30	123	17	two	two	CD
cord-010499-yefxrj30	123	18	at	at	IN
cord-010499-yefxrj30	123	19	Riverside	Riverside	NNP
cord-010499-yefxrj30	123	20	.	.	.
cord-010499-yefxrj30	124	1	In	in	IN
cord-010499-yefxrj30	124	2	every	every	DT
cord-010499-yefxrj30	124	3	cyle	cyle	NN
cord-010499-yefxrj30	124	4	,	,	,
cord-010499-yefxrj30	124	5	the	the	DT
cord-010499-yefxrj30	124	6	most	most	RBS
cord-010499-yefxrj30	124	7	abundant	abundant	JJ
cord-010499-yefxrj30	124	8	PTHamino	pthamino	NN
cord-010499-yefxrj30	124	9	acid	acid	NN
cord-010499-yefxrj30	124	10	released	release	VBN
cord-010499-yefxrj30	124	11	predominates	predominate	VBZ
cord-010499-yefxrj30	124	12	over	over	IN
cord-010499-yefxrj30	124	13	others	other	NNS
cord-010499-yefxrj30	124	14	by	by	IN
cord-010499-yefxrj30	124	15	at	at	IN
cord-010499-yefxrj30	124	16	least	least	JJS
cord-010499-yefxrj30	124	17	a	a	DT
cord-010499-yefxrj30	124	18	factor	factor	NN
cord-010499-yefxrj30	124	19	of	of	IN
cord-010499-yefxrj30	124	20	two	two	CD
cord-010499-yefxrj30	124	21	,	,	,
cord-010499-yefxrj30	124	22	affording	afford	VBG
cord-010499-yefxrj30	124	23	a	a	DT
cord-010499-yefxrj30	124	24	clear	clear	JJ
cord-010499-yefxrj30	124	25	signal	signal	NN
cord-010499-yefxrj30	124	26	of	of	IN
cord-010499-yefxrj30	124	27	the	the	DT
cord-010499-yefxrj30	124	28	primary	primary	JJ
cord-010499-yefxrj30	124	29	sequence	sequence	NN
cord-010499-yefxrj30	124	30	.	.	.
cord-010499-yefxrj30	125	1	Secondary	secondary	JJ
cord-010499-yefxrj30	125	2	signals	signal	NNS
cord-010499-yefxrj30	125	3	reflect	reflect	VBP
cord-010499-yefxrj30	125	4	a	a	DT
cord-010499-yefxrj30	125	5	variety	variety	NN
cord-010499-yefxrj30	125	6	of	of	IN
cord-010499-yefxrj30	125	7	artefacts	artefact	NNS
cord-010499-yefxrj30	125	8	.	.	.
cord-010499-yefxrj30	126	1	One	one	CD
cord-010499-yefxrj30	126	2	is	be	VBZ
cord-010499-yefxrj30	126	3	minor	minor	JJ
cord-010499-yefxrj30	126	4	peaks	peak	NNS
cord-010499-yefxrj30	126	5	which	which	WDT
cord-010499-yefxrj30	126	6	anticipate	anticipate	VBP
cord-010499-yefxrj30	126	7	the	the	DT
cord-010499-yefxrj30	126	8	next	next	JJ
cord-010499-yefxrj30	126	9	cycle	cycle	NN
cord-010499-yefxrj30	126	10	(	(	-LRB-
cord-010499-yefxrj30	126	11	for	for	IN
cord-010499-yefxrj30	126	12	example	example	NN
cord-010499-yefxrj30	126	13	,	,	,
cord-010499-yefxrj30	126	14	F	F	NNP
cord-010499-yefxrj30	126	15	in	in	IN
cord-010499-yefxrj30	126	16	cycle	cycle	NNP
cord-010499-yefxrj30	126	17	8	8	CD
cord-010499-yefxrj30	126	18	,	,	,
cord-010499-yefxrj30	126	19	R	r	NN
cord-010499-yefxrj30	126	20	in	in	IN
cord-010499-yefxrj30	126	21	cycle	cycle	NN
cord-010499-yefxrj30	126	22	10	10	CD
cord-010499-yefxrj30	126	23	,	,	,
cord-010499-yefxrj30	126	24	E	E	NNP
cord-010499-yefxrj30	126	25	in	in	IN
cord-010499-yefxrj30	126	26	cycle	cycle	NN
cord-010499-yefxrj30	126	27	11	11	CD
cord-010499-yefxrj30	126	28	,	,	,
cord-010499-yefxrj30	126	29	and	and	CC
cord-010499-yefxrj30	126	30	G	g	NN
cord-010499-yefxrj30	126	31	in	in	IN
cord-010499-yefxrj30	126	32	cycle	cycle	NN
cord-010499-yefxrj30	126	33	12	12	CD
cord-010499-yefxrj30	126	34	}	}	-RRB-
cord-010499-yefxrj30	126	35	,	,	,
cord-010499-yefxrj30	126	36	presumably	presumably	RB
cord-010499-yefxrj30	126	37	owing	owe	VBG
cord-010499-yefxrj30	126	38	to	to	IN
cord-010499-yefxrj30	126	39	a	a	DT
cord-010499-yefxrj30	126	40	minority	minority	NN
cord-010499-yefxrj30	126	41	of	of	IN
cord-010499-yefxrj30	126	42	the	the	DT
cord-010499-yefxrj30	126	43	protein	protein	NN
cord-010499-yefxrj30	126	44	that	that	WDT
cord-010499-yefxrj30	126	45	is	be	VBZ
cord-010499-yefxrj30	126	46	one	one	CD
cord-010499-yefxrj30	126	47	amino	amino	NN
cord-010499-yefxrj30	126	48	acid	acid	NN
cord-010499-yefxrj30	126	49	shorter	shorter	RBR
cord-010499-yefxrj30	126	50	on	on	IN
cord-010499-yefxrj30	126	51	the	the	DT
cord-010499-yefxrj30	126	52	/V	/v	NN
cord-010499-yefxrj30	126	53	-	-	HYPH
cord-010499-yefxrj30	126	54	terminus	terminus	NN
cord-010499-yefxrj30	126	55	than	than	IN
cord-010499-yefxrj30	126	56	the	the	DT
cord-010499-yefxrj30	126	57	bulk	bulk	NN
cord-010499-yefxrj30	126	58	of	of	IN
cord-010499-yefxrj30	126	59	the	the	DT
cord-010499-yefxrj30	126	60	material	material	NN
cord-010499-yefxrj30	126	61	.	.	.
cord-010499-yefxrj30	127	1	Exponential	exponential	JJ
cord-010499-yefxrj30	127	2	cells	cell	NNS
cord-010499-yefxrj30	127	3	carrying	carry	VBG
cord-010499-yefxrj30	127	4	plasmid	plasmid	NN
cord-010499-yefxrj30	127	5	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	127	6	or	or	CC
cord-010499-yefxrj30	127	7	the	the	DT
cord-010499-yefxrj30	127	8	control	control	NN
cord-010499-yefxrj30	127	9	lacZ	lacz	XX
cord-010499-yefxrj30	127	10	'	'	POS
cord-010499-yefxrj30	127	11	plasmid	plasmid	NN
cord-010499-yefxrj30	127	12	pBWIlOO	pBWIlOO	NNP
cord-010499-yefxrj30	127	13	were	be	VBD
cord-010499-yefxrj30	127	14	subjected	subject	VBN
cord-010499-yefxrj30	127	15	to	to	IN
cord-010499-yefxrj30	127	16	limilation	limilation	NN
cord-010499-yefxrj30	127	17	for	for	IN
cord-010499-yefxrj30	127	18	phenylalanyt	phenylalanyt	NN
cord-010499-yefxrj30	127	19	-	-	HYPH
cord-010499-yefxrj30	127	20	WNA	wna	NN
cord-010499-yefxrj30	127	21	by	by	IN
cord-010499-yefxrj30	127	22	addition	addition	NN
cord-010499-yefxrj30	127	23	of	of	IN
cord-010499-yefxrj30	127	24	phenylalanine	phenylalanine	NN
cord-010499-yefxrj30	127	25	-	-	:
cord-010499-yefxrj30	127	26	i^ydTOxamate	i^ydtoxamate	NN
cord-010499-yefxrj30	127	27	(	(	-LRB-
cord-010499-yefxrj30	127	28	PHX	PHX	NNP
cord-010499-yefxrj30	127	29	)	)	-RRB-
cord-010499-yefxrj30	128	1	al	al	NNP
cord-010499-yefxrj30	128	2	the	the	DT
cord-010499-yefxrj30	128	3	indicated	indicate	VBN
cord-010499-yefxrj30	128	4	concentrations	concentration	NNS
cord-010499-yefxrj30	128	5	;	;	:
cord-010499-yefxrj30	128	6	and	and	CC
cord-010499-yefxrj30	128	7	for	for	IN
cord-010499-yefxrj30	128	8	arginine	arginine	NN
cord-010499-yefxrj30	128	9	by	by	IN
cord-010499-yefxrj30	128	10	centrifuging	centrifuge	VBG
cord-010499-yefxrj30	128	11	and	and	CC
cord-010499-yefxrj30	128	12	washing	wash	VBG
cord-010499-yefxrj30	128	13	the	the	DT
cord-010499-yefxrj30	128	14	cells	cell	NNS
cord-010499-yefxrj30	128	15	,	,	,
cord-010499-yefxrj30	128	16	and	and	CC
cord-010499-yefxrj30	128	17	resuspending	resuspend	VBG
cord-010499-yefxrj30	128	18	them	-PRON-	PRP
cord-010499-yefxrj30	128	19	in	in	IN
cord-010499-yefxrj30	128	20	growth	growth	NN
cord-010499-yefxrj30	128	21	medium	medium	NN
cord-010499-yefxrj30	128	22	containing	contain	VBG
cord-010499-yefxrj30	128	23	the	the	DT
cord-010499-yefxrj30	128	24	indicated	indicate	VBN
cord-010499-yefxrj30	128	25	concentrations	concentration	NNS
cord-010499-yefxrj30	128	26	of	of	IN
cord-010499-yefxrj30	128	27	arginine	arginine	NN
cord-010499-yefxrj30	128	28	-	-	HYPH
cord-010499-yefxrj30	128	29	methyl	methyl	NN
cord-010499-yefxrj30	128	30	-	-	HYPH
cord-010499-yefxrj30	128	31	ester	ester	NN
cord-010499-yefxrj30	128	32	(	(	-LRB-
cord-010499-yefxrj30	128	33	AME	AME	NNP
cord-010499-yefxrj30	128	34	)	)	-RRB-
cord-010499-yefxrj30	128	35	,	,	,
cord-010499-yefxrj30	128	36	with	with	IN
cord-010499-yefxrj30	128	37	a	a	DT
cord-010499-yefxrj30	128	38	control	control	NN
cord-010499-yefxrj30	128	39	culture	culture	NN
cord-010499-yefxrj30	128	40	containing	contain	VBG
cord-010499-yefxrj30	128	41	arginine	arginine	NN
cord-010499-yefxrj30	128	42	at	at	IN
cord-010499-yefxrj30	128	43	our	-PRON-	PRP$
cord-010499-yefxrj30	128	44	standard	standard	JJ
cord-010499-yefxrj30	128	45	concentration	concentration	NN
cord-010499-yefxrj30	128	46	of	of	IN
cord-010499-yefxrj30	128	47	100	100	CD
cord-010499-yefxrj30	128	48	Jig	Jig	NNP
cord-010499-yefxrj30	128	49	ml	ml	NN
cord-010499-yefxrj30	128	50	V	v	NN
cord-010499-yefxrj30	129	1	The	the	DT
cord-010499-yefxrj30	129	2	/ac	/ac	CD
cord-010499-yefxrj30	129	3	promoter	promoter	NN
cord-010499-yefxrj30	129	4	was	be	VBD
cord-010499-yefxrj30	129	5	induced	induce	VBN
cord-010499-yefxrj30	129	6	as	as	IN
cord-010499-yefxrj30	129	7	in	in	IN
cord-010499-yefxrj30	129	8	Table	Table	NNP
cord-010499-yefxrj30	129	9	1	1	CD
cord-010499-yefxrj30	129	10	,	,	,
cord-010499-yefxrj30	129	11	and	and	CC
cord-010499-yefxrj30	129	12	cells	cell	NNS
cord-010499-yefxrj30	129	13	harvested	harvest	VBN
cord-010499-yefxrj30	129	14	for	for	IN
cord-010499-yefxrj30	129	15	assay	assay	NN
cord-010499-yefxrj30	129	16	after	after	IN
cord-010499-yefxrj30	129	17	about	about	RB
cord-010499-yefxrj30	129	18	one	one	CD
cord-010499-yefxrj30	129	19	doubling	doubling	NN
cord-010499-yefxrj30	129	20	.	.	.
cord-010499-yefxrj30	130	1	Cultures	culture	NNS
cord-010499-yefxrj30	130	2	are	be	VBP
cord-010499-yefxrj30	130	3	listed	list	VBN
cord-010499-yefxrj30	130	4	in	in	IN
cord-010499-yefxrj30	130	5	order	order	NN
cord-010499-yefxrj30	130	6	of	of	IN
cord-010499-yefxrj30	130	7	decreasing	decrease	VBG
cord-010499-yefxrj30	130	8	growth	growth	NN
cord-010499-yefxrj30	130	9	rate	rate	NN
cord-010499-yefxrj30	130	10	.	.	.
cord-010499-yefxrj30	131	1	Growth	growth	NN
cord-010499-yefxrj30	131	2	rate	rate	NN
cord-010499-yefxrj30	131	3	varies	vary	VBZ
cord-010499-yefxrj30	131	4	directly	directly	RB
cord-010499-yefxrj30	131	5	with	with	IN
cord-010499-yefxrj30	131	6	the	the	DT
cord-010499-yefxrj30	131	7	concentration	concentration	NN
cord-010499-yefxrj30	131	8	of	of	IN
cord-010499-yefxrj30	131	9	AME	AME	NNP
cord-010499-yefxrj30	131	10	,	,	,
cord-010499-yefxrj30	131	11	which	which	WDT
cord-010499-yefxrj30	131	12	serves	serve	VBZ
cord-010499-yefxrj30	131	13	as	as	IN
cord-010499-yefxrj30	131	14	a	a	DT
cord-010499-yefxrj30	131	15	source	source	NN
cord-010499-yefxrj30	131	16	of	of	IN
cord-010499-yefxrj30	131	17	required	require	VBN
cord-010499-yefxrj30	131	18	arginine	arginine	NN
cord-010499-yefxrj30	131	19	,	,	,
cord-010499-yefxrj30	131	20	and	and	CC
cord-010499-yefxrj30	131	21	inversely	inversely	RB
cord-010499-yefxrj30	131	22	with	with	IN
cord-010499-yefxrj30	131	23	the	the	DT
cord-010499-yefxrj30	131	24	concentration	concentration	NN
cord-010499-yefxrj30	131	25	of	of	IN
cord-010499-yefxrj30	131	26	PHX	PHX	NNP
cord-010499-yefxrj30	131	27	,	,	,
cord-010499-yefxrj30	131	28	which	which	WDT
cord-010499-yefxrj30	131	29	inhibits	inhibit	VBZ
cord-010499-yefxrj30	131	30	phenylaianine	phenylaianine	JJ
cord-010499-yefxrj30	131	31	activation	activation	NN
cord-010499-yefxrj30	131	32	.	.	.
cord-010499-yefxrj30	132	1	in	in	IN
cord-010499-yefxrj30	132	2	the	the	DT
cord-010499-yefxrj30	132	3	case	case	NN
cord-010499-yefxrj30	132	4	of	of	IN
cord-010499-yefxrj30	132	5	leucine	leucine	NN
cord-010499-yefxrj30	132	6	limitation	limitation	NN
cord-010499-yefxrj30	132	7	,	,	,
cord-010499-yefxrj30	132	8	a	a	DT
cord-010499-yefxrj30	132	9	different	different	JJ
cord-010499-yefxrj30	132	10	outcome	outcome	NN
cord-010499-yefxrj30	132	11	was	be	VBD
cord-010499-yefxrj30	132	12	suggested	suggest	VBN
cord-010499-yefxrj30	132	13	in	in	IN
cord-010499-yefxrj30	132	14	preliminary	preliminary	JJ
cord-010499-yefxrj30	132	15	screening	screening	NN
cord-010499-yefxrj30	132	16	by	by	IN
cord-010499-yefxrj30	132	17	a	a	DT
cord-010499-yefxrj30	132	18	crude	crude	NN
cord-010499-yefxrj30	132	19	,	,	,
cord-010499-yefxrj30	132	20	qualitative	qualitative	JJ
cord-010499-yefxrj30	132	21	Petri	Petri	NNP
cord-010499-yefxrj30	132	22	plate	plate	NN
cord-010499-yefxrj30	132	23	assay	assay	NN
cord-010499-yefxrj30	132	24	(	(	-LRB-
cord-010499-yefxrj30	132	25	Kuriand	Kuriand	NNP
cord-010499-yefxrj30	132	26	and	and	CC
cord-010499-yefxrj30	132	27	Gallant	Gallant	NNP
cord-010499-yefxrj30	132	28	,	,	,
cord-010499-yefxrj30	132	29	1986	1986	CD
cord-010499-yefxrj30	132	30	)	)	-RRB-
cord-010499-yefxrj30	132	31	.	.	.
cord-010499-yefxrj30	133	1	Quantitative	quantitative	JJ
cord-010499-yefxrj30	133	2	data	datum	NNS
cord-010499-yefxrj30	133	3	on	on	IN
cord-010499-yefxrj30	133	4	log	log	NN
cord-010499-yefxrj30	133	5	-	-	HYPH
cord-010499-yefxrj30	133	6	phase	phase	NN
cord-010499-yefxrj30	133	7	cells	cell	NNS
cord-010499-yefxrj30	133	8	are	be	VBP
cord-010499-yefxrj30	133	9	shown	show	VBN
cord-010499-yefxrj30	133	10	in	in	IN
cord-010499-yefxrj30	133	11	Table	Table	NNP
cord-010499-yefxrj30	133	12	3	3	CD
cord-010499-yefxrj30	133	13	.	.	.
cord-010499-yefxrj30	134	1	In	in	IN
cord-010499-yefxrj30	134	2	the	the	DT
cord-010499-yefxrj30	134	3	lacZ*ĉ	lacZ*ĉ	NNP
cord-010499-yefxrj30	134	4	ontroi	ontroi	NN
cord-010499-yefxrj30	134	5	,	,	,
cord-010499-yefxrj30	134	6	leucine	leucine	NN
cord-010499-yefxrj30	134	7	limitation	limitation	NN
cord-010499-yefxrj30	134	8	progressiveiy	progressiveiy	NNP
cord-010499-yefxrj30	134	9	restricted	restricted	JJ
cord-010499-yefxrj30	134	10	enzyme	enzyme	NN
cord-010499-yefxrj30	134	11	synthesis	synthesis	NN
cord-010499-yefxrj30	134	12	,	,	,
cord-010499-yefxrj30	134	13	reducing	reduce	VBG
cord-010499-yefxrj30	134	14	it	-PRON-	PRP
cord-010499-yefxrj30	134	15	very	very	RB
cord-010499-yefxrj30	134	16	severeiy	severeiy	NNP
cord-010499-yefxrj30	134	17	at	at	IN
cord-010499-yefxrj30	134	18	iow	iow	NNP
cord-010499-yefxrj30	134	19	growth	growth	NN
cord-010499-yefxrj30	134	20	rates	rate	NNS
cord-010499-yefxrj30	134	21	,	,	,
cord-010499-yefxrj30	134	22	in	in	IN
cord-010499-yefxrj30	134	23	the	the	DT
cord-010499-yefxrj30	134	24	HIV	HIV	NNP
cord-010499-yefxrj30	134	25	construct	construct	VB
cord-010499-yefxrj30	134	26	,	,	,
cord-010499-yefxrj30	134	27	on	on	IN
cord-010499-yefxrj30	134	28	the	the	DT
cord-010499-yefxrj30	134	29	other	other	JJ
cord-010499-yefxrj30	134	30	hand	hand	NN
cord-010499-yefxrj30	134	31	,	,	,
cord-010499-yefxrj30	134	32	there	there	EX
cord-010499-yefxrj30	134	33	was	be	VBD
cord-010499-yefxrj30	134	34	no	no	DT
cord-010499-yefxrj30	134	35	such	such	JJ
cord-010499-yefxrj30	134	36	restriction	restriction	NN
cord-010499-yefxrj30	134	37	,	,	,
cord-010499-yefxrj30	134	38	but	but	CC
cord-010499-yefxrj30	134	39	ratlner	ratlner	NNP
cord-010499-yefxrj30	134	40	a	a	DT
cord-010499-yefxrj30	134	41	smali	smali	NN
cord-010499-yefxrj30	134	42	stimuiation	stimuiation	NN
cord-010499-yefxrj30	134	43	of	of	IN
cord-010499-yefxrj30	134	44	enzyme	enzyme	NN
cord-010499-yefxrj30	134	45	synthesis	synthesis	NN
cord-010499-yefxrj30	134	46	.	.	.
cord-010499-yefxrj30	135	1	if	if	IN
cord-010499-yefxrj30	135	2	this	this	DT
cord-010499-yefxrj30	135	3	effect	effect	NN
cord-010499-yefxrj30	135	4	is	be	VBZ
cord-010499-yefxrj30	135	5	caused	cause	VBN
cord-010499-yefxrj30	135	6	by	by	IN
cord-010499-yefxrj30	135	7	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	135	8	at	at	IN
cord-010499-yefxrj30	135	9	the	the	DT
cord-010499-yefxrj30	135	10	ieucine	ieucine	NNP
cord-010499-yefxrj30	135	11	codon	codon	NN
cord-010499-yefxrj30	135	12	within	within	IN
cord-010499-yefxrj30	135	13	the	the	DT
cord-010499-yefxrj30	135	14	HIV	HIV	NNP
cord-010499-yefxrj30	135	15	sequence	sequence	NN
cord-010499-yefxrj30	135	16	,	,	,
cord-010499-yefxrj30	135	17	then	then	RB
cord-010499-yefxrj30	135	18	it	-PRON-	PRP
cord-010499-yefxrj30	135	19	should	should	MD
cord-010499-yefxrj30	135	20	be	be	VB
cord-010499-yefxrj30	135	21	eliminated	eliminate	VBN
cord-010499-yefxrj30	135	22	by	by	IN
cord-010499-yefxrj30	135	23	eliminating	eliminate	VBG
cord-010499-yefxrj30	135	24	that	that	IN
cord-010499-yefxrj30	135	25	ieucine	ieucine	NNP
cord-010499-yefxrj30	135	26	codon	codon	NN
cord-010499-yefxrj30	135	27	.	.	.
cord-010499-yefxrj30	136	1	As	as	IN
cord-010499-yefxrj30	136	2	an	an	DT
cord-010499-yefxrj30	136	3	additional	additional	JJ
cord-010499-yefxrj30	136	4	control	control	NN
cord-010499-yefxrj30	136	5	,	,	,
cord-010499-yefxrj30	136	6	therefore	therefore	RB
cord-010499-yefxrj30	136	7	,	,	,
cord-010499-yefxrj30	136	8	we	-PRON-	PRP
cord-010499-yefxrj30	136	9	tested	test	VBD
cord-010499-yefxrj30	136	10	201-U7	201-u7	CD
cord-010499-yefxrj30	136	11	,	,	,
cord-010499-yefxrj30	136	12	a	a	DT
cord-010499-yefxrj30	136	13	construct	construct	NN
cord-010499-yefxrj30	136	14	that	that	WDT
cord-010499-yefxrj30	136	15	is	be	VBZ
cord-010499-yefxrj30	136	16	identicai	identicai	NN
cord-010499-yefxrj30	136	17	to	to	IN
cord-010499-yefxrj30	136	18	201	201	CD
cord-010499-yefxrj30	136	19	except	except	IN
cord-010499-yefxrj30	136	20	for	for	IN
cord-010499-yefxrj30	136	21	the	the	DT
cord-010499-yefxrj30	136	22	conversion	conversion	NN
cord-010499-yefxrj30	136	23	of	of	IN
cord-010499-yefxrj30	136	24	the	the	DT
cord-010499-yefxrj30	136	25	leucine	leucine	NN
cord-010499-yefxrj30	136	26	UUA	UUA	NNP
cord-010499-yefxrj30	136	27	codon	codon	NN
cord-010499-yefxrj30	136	28	to	to	IN
cord-010499-yefxrj30	136	29	UUU	UUU	NNP
cord-010499-yefxrj30	136	30	(	(	-LRB-
cord-010499-yefxrj30	136	31	see	see	VB
cord-010499-yefxrj30	136	32	Fig	Fig	NNP
cord-010499-yefxrj30	136	33	.	.	NNP
cord-010499-yefxrj30	136	34	1	1	CD
cord-010499-yefxrj30	136	35	)	)	-RRB-
cord-010499-yefxrj30	136	36	.	.	.
cord-010499-yefxrj30	137	1	In	in	IN
cord-010499-yefxrj30	137	2	this	this	DT
cord-010499-yefxrj30	137	3	construct	construct	NN
cord-010499-yefxrj30	137	4	,	,	,
cord-010499-yefxrj30	137	5	ieucine	ieucine	JJ
cord-010499-yefxrj30	137	6	limitation	limitation	NN
cord-010499-yefxrj30	137	7	did	do	VBD
cord-010499-yefxrj30	137	8	not	not	RB
cord-010499-yefxrj30	137	9	stimulate	stimulate	VB
cord-010499-yefxrj30	137	10	enzyme	enzyme	NN
cord-010499-yefxrj30	137	11	synthesis	synthesis	NN
cord-010499-yefxrj30	137	12	as	as	IN
cord-010499-yefxrj30	137	13	in	in	IN
cord-010499-yefxrj30	137	14	201	201	CD
cord-010499-yefxrj30	137	15	,	,	,
cord-010499-yefxrj30	137	16	but	but	CC
cord-010499-yefxrj30	137	17	ratfier	ratfier	NNP
cord-010499-yefxrj30	137	18	reduced	reduce	VBD
cord-010499-yefxrj30	137	19	it	-PRON-	PRP
cord-010499-yefxrj30	137	20	,	,	,
cord-010499-yefxrj30	137	21	as	as	IN
cord-010499-yefxrj30	137	22	it	-PRON-	PRP
cord-010499-yefxrj30	137	23	did	do	VBD
cord-010499-yefxrj30	137	24	in	in	IN
cord-010499-yefxrj30	137	25	the	the	DT
cord-010499-yefxrj30	137	26	wiid	wiid	NN
cord-010499-yefxrj30	137	27	type	type	NN
cord-010499-yefxrj30	137	28	(	(	-LRB-
cord-010499-yefxrj30	137	29	Table	Table	NNP
cord-010499-yefxrj30	137	30	4	4	CD
cord-010499-yefxrj30	137	31	)	)	-RRB-
cord-010499-yefxrj30	137	32	.	.	.
cord-010499-yefxrj30	138	1	The	the	DT
cord-010499-yefxrj30	138	2	reduction	reduction	NN
cord-010499-yefxrj30	138	3	was	be	VBD
cord-010499-yefxrj30	138	4	a	a	DT
cord-010499-yefxrj30	138	5	good	good	JJ
cord-010499-yefxrj30	138	6	deal	deal	NN
cord-010499-yefxrj30	138	7	less	less	JJR
cord-010499-yefxrj30	138	8	than	than	IN
cord-010499-yefxrj30	138	9	in	in	IN
cord-010499-yefxrj30	138	10	the	the	DT
cord-010499-yefxrj30	138	11	wiid	wiid	NN
cord-010499-yefxrj30	138	12	type	type	NN
cord-010499-yefxrj30	138	13	,	,	,
cord-010499-yefxrj30	138	14	suggesting	suggest	VBG
cord-010499-yefxrj30	138	15	that	that	IN
cord-010499-yefxrj30	138	16	some	some	DT
cord-010499-yefxrj30	138	17	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	138	18	at	at	IN
cord-010499-yefxrj30	138	19	various	various	JJ
cord-010499-yefxrj30	138	20	positions	position	NNS
cord-010499-yefxrj30	138	21	still	still	RB
cord-010499-yefxrj30	138	22	occurs	occur	VBZ
cord-010499-yefxrj30	138	23	in	in	IN
cord-010499-yefxrj30	138	24	201-U7	201-u7	CD
cord-010499-yefxrj30	138	25	,	,	,
cord-010499-yefxrj30	138	26	so	so	IN
cord-010499-yefxrj30	138	27	as	as	IN
cord-010499-yefxrj30	138	28	to	to	TO
cord-010499-yefxrj30	138	29	offset	offset	VB
cord-010499-yefxrj30	138	30	partly	partly	RB
cord-010499-yefxrj30	138	31	the	the	DT
cord-010499-yefxrj30	138	32	effect	effect	NN
cord-010499-yefxrj30	138	33	of	of	IN
cord-010499-yefxrj30	138	34	reduced	reduce	VBN
cord-010499-yefxrj30	138	35	lacZ	lacZ	NNP
cord-010499-yefxrj30	138	36	expression	expression	NN
cord-010499-yefxrj30	138	37	.	.	.
cord-010499-yefxrj30	139	1	However	however	RB
cord-010499-yefxrj30	139	2	,	,	,
cord-010499-yefxrj30	139	3	the	the	DT
cord-010499-yefxrj30	139	4	difference	difference	NN
cord-010499-yefxrj30	139	5	between	between	IN
cord-010499-yefxrj30	139	6	tine	tine	JJ
cord-010499-yefxrj30	139	7	response	response	NN
cord-010499-yefxrj30	139	8	of	of	IN
cord-010499-yefxrj30	139	9	201	201	CD
cord-010499-yefxrj30	139	10	and	and	CC
cord-010499-yefxrj30	139	11	that	that	DT
cord-010499-yefxrj30	139	12	of	of	IN
cord-010499-yefxrj30	139	13	201-U7	201-u7	CD
cord-010499-yefxrj30	139	14	demonstrates	demonstrate	VBZ
cord-010499-yefxrj30	139	15	that	that	IN
cord-010499-yefxrj30	139	16	the	the	DT
cord-010499-yefxrj30	139	17	leucine	leucine	NN
cord-010499-yefxrj30	139	18	codon	codon	NN
cord-010499-yefxrj30	139	19	eliminated	eliminate	VBN
cord-010499-yefxrj30	139	20	in	in	IN
cord-010499-yefxrj30	139	21	the	the	DT
cord-010499-yefxrj30	139	22	latter	latter	NN
cord-010499-yefxrj30	139	23	must	must	MD
cord-010499-yefxrj30	139	24	be	be	VB
cord-010499-yefxrj30	139	25	a	a	DT
cord-010499-yefxrj30	139	26	major	major	JJ
cord-010499-yefxrj30	139	27	determinant	determinant	NN
cord-010499-yefxrj30	139	28	of	of	IN
cord-010499-yefxrj30	139	29	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	139	30	induced	induce	VBN
cord-010499-yefxrj30	139	31	by	by	IN
cord-010499-yefxrj30	139	32	leucine	leucine	NN
cord-010499-yefxrj30	139	33	limitation	limitation	NN
cord-010499-yefxrj30	139	34	.	.	.
cord-010499-yefxrj30	140	1	Decisive	decisive	JJ
cord-010499-yefxrj30	140	2	identification	identification	NN
cord-010499-yefxrj30	140	3	of	of	IN
cord-010499-yefxrj30	140	4	the	the	DT
cord-010499-yefxrj30	140	5	frameshift	frameshift	NN
cord-010499-yefxrj30	140	6	site	site	NN
cord-010499-yefxrj30	140	7	during	during	IN
cord-010499-yefxrj30	140	8	leucine	leucine	NN
cord-010499-yefxrj30	140	9	iimitation	iimitation	NN
cord-010499-yefxrj30	140	10	was	be	VBD
cord-010499-yefxrj30	140	11	obtained	obtain	VBN
cord-010499-yefxrj30	140	12	from	from	IN
cord-010499-yefxrj30	140	13	protein	protein	NN
cord-010499-yefxrj30	140	14	sequence	sequence	NN
cord-010499-yefxrj30	140	15	anaiysis	anaiysis	NN
cord-010499-yefxrj30	140	16	,	,	,
cord-010499-yefxrj30	140	17	as	as	IN
cord-010499-yefxrj30	140	18	described	describe	VBN
cord-010499-yefxrj30	140	19	earlier	early	RBR
cord-010499-yefxrj30	140	20	.	.	.
cord-010499-yefxrj30	141	1	The	the	DT
cord-010499-yefxrj30	141	2	resuits	resuit	NNS
cord-010499-yefxrj30	141	3	are	be	VBP
cord-010499-yefxrj30	141	4	shown	show	VBN
cord-010499-yefxrj30	141	5	in	in	IN
cord-010499-yefxrj30	141	6	Table	Table	NNP
cord-010499-yefxrj30	141	7	3	3	CD
cord-010499-yefxrj30	141	8	.	.	.
cord-010499-yefxrj30	142	1	Relative	relative	JJ
cord-010499-yefxrj30	142	2	growth	growth	NN
cord-010499-yefxrj30	142	3	rates	rate	NNS
cord-010499-yefxrj30	142	4	and	and	CC
cord-010499-yefxrj30	142	5	differential	differential	JJ
cord-010499-yefxrj30	142	6	rates	rate	NNS
cord-010499-yefxrj30	142	7	of	of	IN
cord-010499-yefxrj30	142	8	(	(	-LRB-
cord-010499-yefxrj30	142	9	3-galactosidase	3-galactosidase	CD
cord-010499-yefxrj30	142	10	synthesis	synthesis	NN
cord-010499-yefxrj30	142	11	during	during	IN
cord-010499-yefxrj30	142	12	leucine	leucine	NN
cord-010499-yefxrj30	142	13	limitation	limitation	NN
cord-010499-yefxrj30	142	14	.	.	.
cord-010499-yefxrj30	143	1	Exponential	exponential	JJ
cord-010499-yefxrj30	143	2	cells	cell	NNS
cord-010499-yefxrj30	143	3	carrying	carry	VBG
cord-010499-yefxrj30	143	4	plasmid	plasmid	NN
cord-010499-yefxrj30	143	5	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	143	6	were	be	VBD
cord-010499-yefxrj30	143	7	spun	spin	VBN
cord-010499-yefxrj30	143	8	,	,	,
cord-010499-yefxrj30	143	9	washed	wash	VBN
cord-010499-yefxrj30	143	10	,	,	,
cord-010499-yefxrj30	143	11	and	and	CC
cord-010499-yefxrj30	143	12	resuspended	resuspend	VBD
cord-010499-yefxrj30	143	13	in	in	IN
cord-010499-yefxrj30	143	14	medium	medium	NN
cord-010499-yefxrj30	143	15	supplemented	supplement	VBN
cord-010499-yefxrj30	143	16	with	with	IN
cord-010499-yefxrj30	143	17	the	the	DT
cord-010499-yefxrj30	143	18	indicated	indicate	VBN
cord-010499-yefxrj30	143	19	concentrations	concentration	NNS
cord-010499-yefxrj30	143	20	of	of	IN
cord-010499-yefxrj30	143	21	leucine	leucine	NN
cord-010499-yefxrj30	143	22	-	-	HYPH
cord-010499-yefxrj30	143	23	methyl	methyl	NN
cord-010499-yefxrj30	143	24	-	-	HYPH
cord-010499-yefxrj30	143	25	ester	ester	NN
cord-010499-yefxrj30	143	26	(	(	-LRB-
cord-010499-yefxrj30	143	27	LME	LME	NNP
cord-010499-yefxrj30	143	28	)	)	-RRB-
cord-010499-yefxrj30	143	29	.	.	.
cord-010499-yefxrj30	144	1	These	these	DT
cord-010499-yefxrj30	144	2	were	be	VBD
cord-010499-yefxrj30	144	3	grown	grow	VBN
cord-010499-yefxrj30	144	4	in	in	IN
cord-010499-yefxrj30	144	5	parallel	parallel	NN
cord-010499-yefxrj30	144	6	with	with	IN
cord-010499-yefxrj30	144	7	a	a	DT
cord-010499-yefxrj30	144	8	control	control	NN
cord-010499-yefxrj30	144	9	aliquot	aliquot	NN
cord-010499-yefxrj30	144	10	retumed	retume	VBN
cord-010499-yefxrj30	144	11	to	to	IN
cord-010499-yefxrj30	144	12	growth	growth	NN
cord-010499-yefxrj30	144	13	in	in	IN
cord-010499-yefxrj30	144	14	leucine	leucine	NN
cord-010499-yefxrj30	144	15	at	at	IN
cord-010499-yefxrj30	144	16	lOOtigml	lOOtigml	NNP
cord-010499-yefxrj30	144	17	'	'	''
cord-010499-yefxrj30	144	18	'	'	''
cord-010499-yefxrj30	144	19	.	.	.
cord-010499-yefxrj30	145	1	The	the	DT
cord-010499-yefxrj30	145	2	entries	entry	NNS
cord-010499-yefxrj30	145	3	show	show	VBP
cord-010499-yefxrj30	145	4	growth	growth	NN
cord-010499-yefxrj30	145	5	rates	rate	NNS
cord-010499-yefxrj30	145	6	and	and	CC
cord-010499-yefxrj30	145	7	differential	differential	JJ
cord-010499-yefxrj30	145	8	rates	rate	NNS
cord-010499-yefxrj30	145	9	of	of	IN
cord-010499-yefxrj30	145	10	enzyme	enzyme	NN
cord-010499-yefxrj30	145	11	synthesis	synthesis	NN
cord-010499-yefxrj30	145	12	relative	relative	JJ
cord-010499-yefxrj30	145	13	to	to	IN
cord-010499-yefxrj30	145	14	the	the	DT
cord-010499-yefxrj30	145	15	control	control	NN
cord-010499-yefxrj30	145	16	leucine	leucine	NN
cord-010499-yefxrj30	145	17	culture	culture	NN
cord-010499-yefxrj30	145	18	,	,	,
cord-010499-yefxrj30	145	19	expressed	express	VBD
cord-010499-yefxrj30	145	20	as	as	IN
cord-010499-yefxrj30	145	21	mean	mean	JJ
cord-010499-yefxrj30	145	22	values	value	NNS
cord-010499-yefxrj30	146	1	i^	i^	NNP
cord-010499-yefxrj30	146	2	standard	standard	JJ
cord-010499-yefxrj30	146	3	error	error	NN
cord-010499-yefxrj30	146	4	(	(	-LRB-
cord-010499-yefxrj30	146	5	number	number	NN
cord-010499-yefxrj30	146	6	replicate	replicate	VBP
cord-010499-yefxrj30	146	7	experiments	experiment	NNS
cord-010499-yefxrj30	146	8	)	)	-RRB-
cord-010499-yefxrj30	146	9	.	.	.
cord-010499-yefxrj30	147	1	The	the	DT
cord-010499-yefxrj30	147	2	mean	mean	JJ
cord-010499-yefxrj30	147	3	control	control	NN
cord-010499-yefxrj30	147	4	differential	differential	NN
cord-010499-yefxrj30	147	5	rates	rate	NNS
cord-010499-yefxrj30	147	6	in	in	IN
cord-010499-yefxrj30	147	7	these	these	DT
cord-010499-yefxrj30	147	8	experiments	experiment	NNS
cord-010499-yefxrj30	147	9	were	be	VBD
cord-010499-yefxrj30	147	10	2.3	2.3	CD
cord-010499-yefxrj30	147	11	±	±	CD
cord-010499-yefxrj30	147	12	0.16	0.16	CD
cord-010499-yefxrj30	147	13	(	(	-LRB-
cord-010499-yefxrj30	147	14	6	6	CD
cord-010499-yefxrj30	147	15	}	}	-RRB-
cord-010499-yefxrj30	147	16	for	for	IN
cord-010499-yefxrj30	147	17	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	147	18	and	and	CC
cord-010499-yefxrj30	147	19	191	191	CD
cord-010499-yefxrj30	147	20	±	±	CD
cord-010499-yefxrj30	147	21	44	44	CD
cord-010499-yefxrj30	147	22	(	(	-LRB-
cord-010499-yefxrj30	147	23	4	4	CD
cord-010499-yefxrj30	147	24	)	)	-RRB-
cord-010499-yefxrj30	147	25	forpBWIIOO	forpBWIIOO	NNP
cord-010499-yefxrj30	147	26	.	.	.
cord-010499-yefxrj30	148	1	Fig	Fig	NNP
cord-010499-yefxrj30	148	2	.	.	NNP
cord-010499-yefxrj30	148	3	2	2	CD
cord-010499-yefxrj30	148	4	and	and	CC
cord-010499-yefxrj30	148	5	Fig	Fig	NNP
cord-010499-yefxrj30	148	6	.	.	.
cord-010499-yefxrj30	149	1	3	3	LS
cord-010499-yefxrj30	149	2	.	.	.
cord-010499-yefxrj30	150	1	In	in	IN
cord-010499-yefxrj30	150	2	order	order	NN
cord-010499-yefxrj30	150	3	to	to	TO
cord-010499-yefxrj30	150	4	normalize	normalize	VB
cord-010499-yefxrj30	150	5	to	to	IN
cord-010499-yefxrj30	150	6	the	the	DT
cord-010499-yefxrj30	150	7	same	same	JJ
cord-010499-yefxrj30	150	8	number	number	NN
cord-010499-yefxrj30	150	9	of	of	IN
cord-010499-yefxrj30	150	10	picamoles	picamole	NNS
cord-010499-yefxrj30	150	11	,	,	,
cord-010499-yefxrj30	150	12	all	all	PDT
cord-010499-yefxrj30	150	13	the	the	DT
cord-010499-yefxrj30	150	14	values	value	NNS
cord-010499-yefxrj30	150	15	for	for	IN
cord-010499-yefxrj30	150	16	the	the	DT
cord-010499-yefxrj30	150	17	leucine	leucine	NN
cord-010499-yefxrj30	150	18	-	-	HYPH
cord-010499-yefxrj30	150	19	starved	starve	VBN
cord-010499-yefxrj30	150	20	protein	protein	NN
cord-010499-yefxrj30	150	21	were	be	VBD
cord-010499-yefxrj30	150	22	multiplied	multiply	VBN
cord-010499-yefxrj30	150	23	by	by	IN
cord-010499-yefxrj30	150	24	the	the	DT
cord-010499-yefxrj30	150	25	ratio	ratio	NN
cord-010499-yefxrj30	150	26	(	(	-LRB-
cord-010499-yefxrj30	150	27	unstarved/	unstarved/	CD
cord-010499-yefxrj30	150	28	starved	starve	VBN
cord-010499-yefxrj30	150	29	)	)	-RRB-
cord-010499-yefxrj30	150	30	of	of	IN
cord-010499-yefxrj30	150	31	the	the	DT
cord-010499-yefxrj30	150	32	sums	sum	NNS
cord-010499-yefxrj30	150	33	of	of	IN
cord-010499-yefxrj30	150	34	the	the	DT
cord-010499-yefxrj30	150	35	predominant	predominant	JJ
cord-010499-yefxrj30	150	36	peaks	peak	NNS
cord-010499-yefxrj30	150	37	(	(	-LRB-
cord-010499-yefxrj30	150	38	N	N	NNP
cord-010499-yefxrj30	150	39	in	in	IN
cord-010499-yefxrj30	150	40	cycle	cycle	NNP
cord-010499-yefxrj30	150	41	8	8	CD
cord-010499-yefxrj30	150	42	,	,	,
cord-010499-yefxrj30	150	43	F	F	NNP
cord-010499-yefxrj30	150	44	in	in	IN
cord-010499-yefxrj30	150	45	9	9	CD
cord-010499-yefxrj30	150	46	,	,	,
cord-010499-yefxrj30	150	47	R	r	NN
cord-010499-yefxrj30	150	48	in	in	IN
cord-010499-yefxrj30	150	49	11	11	CD
cord-010499-yefxrj30	150	50	,	,	,
cord-010499-yefxrj30	150	51	and	and	CC
cord-010499-yefxrj30	150	52	E	e	NN
cord-010499-yefxrj30	150	53	in	in	IN
cord-010499-yefxrj30	150	54	12	12	CD
cord-010499-yefxrj30	150	55	)	)	-RRB-
cord-010499-yefxrj30	150	56	.	.	.
cord-010499-yefxrj30	151	1	The	the	DT
cord-010499-yefxrj30	151	2	ratios	ratio	NNS
cord-010499-yefxrj30	151	3	of	of	IN
cord-010499-yefxrj30	151	4	leucine	leucine	NN
cord-010499-yefxrj30	151	5	to	to	TO
cord-010499-yefxrj30	151	6	phenylaianine	phenylaianine	VB
cord-010499-yefxrj30	151	7	in	in	IN
cord-010499-yefxrj30	151	8	cycle	cycle	NN
cord-010499-yefxrj30	151	9	10	10	CD
cord-010499-yefxrj30	151	10	of	of	IN
cord-010499-yefxrj30	151	11	the	the	DT
cord-010499-yefxrj30	151	12	two	two	CD
cord-010499-yefxrj30	151	13	sets	set	NNS
cord-010499-yefxrj30	151	14	of	of	IN
cord-010499-yefxrj30	151	15	data	datum	NNS
cord-010499-yefxrj30	151	16	were	be	VBD
cord-010499-yefxrj30	151	17	as	as	IN
cord-010499-yefxrj30	151	18	follows	follow	VBZ
cord-010499-yefxrj30	151	19	.	.	.
cord-010499-yefxrj30	152	1	For	for	IN
cord-010499-yefxrj30	152	2	the	the	DT
cord-010499-yefxrj30	152	3	unstarved	unstarved	JJ
cord-010499-yefxrj30	152	4	case	case	NN
cord-010499-yefxrj30	152	5	,	,	,
cord-010499-yefxrj30	152	6	the	the	DT
cord-010499-yefxrj30	152	7	ratios	ratio	NNS
cord-010499-yefxrj30	152	8	in	in	IN
cord-010499-yefxrj30	152	9	three	three	CD
cord-010499-yefxrj30	152	10	runs	run	NNS
cord-010499-yefxrj30	152	11	were	be	VBD
cord-010499-yefxrj30	152	12	2.55	2.55	CD
cord-010499-yefxrj30	152	13	,	,	,
cord-010499-yefxrj30	152	14	1.9	1.9	CD
cord-010499-yefxrj30	152	15	,	,	,
cord-010499-yefxrj30	152	16	and	and	CC
cord-010499-yefxrj30	152	17	3.5	3.5	CD
cord-010499-yefxrj30	152	18	,	,	,
cord-010499-yefxrj30	152	19	yielding	yield	VBG
cord-010499-yefxrj30	152	20	an	an	DT
cord-010499-yefxrj30	152	21	average	average	NN
cord-010499-yefxrj30	152	22	of	of	IN
cord-010499-yefxrj30	152	23	2,65	2,65	CD
cord-010499-yefxrj30	152	24	with	with	IN
cord-010499-yefxrj30	152	25	a	a	DT
cord-010499-yefxrj30	152	26	standard	standard	JJ
cord-010499-yefxrj30	152	27	error	error	NN
cord-010499-yefxrj30	152	28	of	of	IN
cord-010499-yefxrj30	152	29	0.46	0.46	CD
cord-010499-yefxrj30	152	30	.	.	.
cord-010499-yefxrj30	153	1	For	for	IN
cord-010499-yefxrj30	153	2	the	the	DT
cord-010499-yefxrj30	153	3	ieucine	ieucine	NN
cord-010499-yefxrj30	153	4	-	-	HYPH
cord-010499-yefxrj30	153	5	starved	starve	VBN
cord-010499-yefxrj30	153	6	case	case	NN
cord-010499-yefxrj30	153	7	,	,	,
cord-010499-yefxrj30	153	8	the	the	DT
cord-010499-yefxrj30	153	9	ratios	ratio	NNS
cord-010499-yefxrj30	153	10	in	in	IN
cord-010499-yefxrj30	153	11	four	four	CD
cord-010499-yefxrj30	153	12	runs	run	NNS
cord-010499-yefxrj30	153	13	were	be	VBD
cord-010499-yefxrj30	153	14	0.52	0.52	CD
cord-010499-yefxrj30	153	15	,	,	,
cord-010499-yefxrj30	153	16	0.58	0.58	CD
cord-010499-yefxrj30	153	17	,	,	,
cord-010499-yefxrj30	153	18	0.68	0.68	CD
cord-010499-yefxrj30	153	19	,	,	,
cord-010499-yefxrj30	153	20	and	and	CC
cord-010499-yefxrj30	153	21	0.51	0.51	CD
cord-010499-yefxrj30	153	22	,	,	,
cord-010499-yefxrj30	153	23	yielding	yield	VBG
cord-010499-yefxrj30	153	24	an	an	DT
cord-010499-yefxrj30	153	25	average	average	NN
cord-010499-yefxrj30	153	26	of	of	IN
cord-010499-yefxrj30	153	27	0.57	0.57	CD
cord-010499-yefxrj30	153	28	with	with	IN
cord-010499-yefxrj30	153	29	a	a	DT
cord-010499-yefxrj30	153	30	standard	standard	JJ
cord-010499-yefxrj30	153	31	error	error	NN
cord-010499-yefxrj30	153	32	ot	ot	IN
cord-010499-yefxrj30	153	33	0.039	0.039	CD
cord-010499-yefxrj30	153	34	.	.	.
cord-010499-yefxrj30	154	1	The	the	DT
cord-010499-yefxrj30	154	2	difference	difference	NN
cord-010499-yefxrj30	154	3	is	be	VBZ
cord-010499-yefxrj30	154	4	highly	highly	RB
cord-010499-yefxrj30	154	5	significant	significant	JJ
cord-010499-yefxrj30	155	1	(	(	-LRB-
cord-010499-yefxrj30	155	2	P	p	NN
cord-010499-yefxrj30	155	3	less	less	JJR
cord-010499-yefxrj30	155	4	than	than	IN
cord-010499-yefxrj30	155	5	0.005	0.005	CD
cord-010499-yefxrj30	155	6	)	)	-RRB-
cord-010499-yefxrj30	155	7	by	by	IN
cord-010499-yefxrj30	155	8	the	the	DT
cord-010499-yefxrj30	155	9	la	la	NNP
cord-010499-yefxrj30	155	10	test	test	NN
cord-010499-yefxrj30	156	1	(	(	-LRB-
cord-010499-yefxrj30	156	2	Crow	Crow	NNP
cord-010499-yefxrj30	156	3	et	et	FW
cord-010499-yefxrj30	156	4	ai	ai	NN
cord-010499-yefxrj30	156	5	..	..	CD
cord-010499-yefxrj30	156	6	1969	1969	CD
cord-010499-yefxrj30	156	7	)	)	-RRB-
cord-010499-yefxrj30	156	8	.	.	.
cord-010499-yefxrj30	157	1	The	the	DT
cord-010499-yefxrj30	157	2	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	157	3	sequence	sequence	NN
cord-010499-yefxrj30	157	4	in	in	IN
cord-010499-yefxrj30	157	5	the	the	DT
cord-010499-yefxrj30	157	6	region	region	NN
cord-010499-yefxrj30	157	7	of	of	IN
cord-010499-yefxrj30	157	8	interest	interest	NN
cord-010499-yefxrj30	157	9	is	be	VBZ
cord-010499-yefxrj30	157	10	shown	show	VBN
cord-010499-yefxrj30	157	11	below	below	IN
cord-010499-yefxrj30	157	12	the	the	DT
cord-010499-yefxrj30	157	13	cycle	cycle	NN
cord-010499-yefxrj30	157	14	bar	bar	NN
cord-010499-yefxrj30	157	15	plot	plot	NN
cord-010499-yefxrj30	157	16	,	,	,
cord-010499-yefxrj30	157	17	with	with	IN
cord-010499-yefxrj30	157	18	the	the	DT
cord-010499-yefxrj30	157	19	expected	expect	VBN
cord-010499-yefxrj30	157	20	amino	amino	JJ
cord-010499-yefxrj30	157	21	acids	acid	NNS
cord-010499-yefxrj30	157	22	read	read	VBP
cord-010499-yefxrj30	157	23	in	in	IN
cord-010499-yefxrj30	157	24	the	the	DT
cord-010499-yefxrj30	157	25	initial	initial	NN
cord-010499-yefxrj30	157	26	(	(	-LRB-
cord-010499-yefxrj30	157	27	0	0	NFP
cord-010499-yefxrj30	157	28	)	)	-RRB-
cord-010499-yefxrj30	157	29	reading	reading	NN
cord-010499-yefxrj30	157	30	frame	frame	NN
cord-010499-yefxrj30	157	31	shown	show	VBN
cord-010499-yefxrj30	157	32	above	above	IN
cord-010499-yefxrj30	157	33	the	the	DT
cord-010499-yefxrj30	157	34	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	157	35	sequence	sequence	NN
cord-010499-yefxrj30	157	36	,	,	,
cord-010499-yefxrj30	157	37	and	and	CC
cord-010499-yefxrj30	157	38	the	the	DT
cord-010499-yefxrj30	157	39	expected	expect	VBN
cord-010499-yefxrj30	157	40	amino	amino	JJ
cord-010499-yefxrj30	157	41	acids	acid	NNS
cord-010499-yefxrj30	157	42	read	read	VBP
cord-010499-yefxrj30	157	43	in	in	IN
cord-010499-yefxrj30	157	44	the	the	DT
cord-010499-yefxrj30	157	45	leftward	leftward	JJ
cord-010499-yefxrj30	157	46	reading	reading	NN
cord-010499-yefxrj30	157	47	frame	frame	NN
cord-010499-yefxrj30	157	48	shown	show	VBN
cord-010499-yefxrj30	157	49	below	below	RB
cord-010499-yefxrj30	157	50	.	.	.
cord-010499-yefxrj30	158	1	Solid	solid	JJ
cord-010499-yefxrj30	158	2	bars	bar	NNS
cord-010499-yefxrj30	158	3	=	=	NFP
cord-010499-yefxrj30	159	1	HIV-201	hiv-201	DT
cord-010499-yefxrj30	159	2	unstarved	unstarved	JJ
cord-010499-yefxrj30	159	3	(	(	-LRB-
cord-010499-yefxrj30	159	4	+	+	CC
cord-010499-yefxrj30	159	5	Leu	Leu	NNP
cord-010499-yefxrj30	159	6	)	)	-RRB-
cord-010499-yefxrj30	159	7	;	;	:
cord-010499-yefxrj30	159	8	open	open	JJ
cord-010499-yefxrj30	159	9	bars	bar	NNS
cord-010499-yefxrj30	159	10	=	=	NFP
cord-010499-yefxrj30	160	1	HIV--201	HIV--201	NNP
cord-010499-yefxrj30	160	2	stan	stan	NNP
cord-010499-yefxrj30	160	3	/	/	SYM
cord-010499-yefxrj30	160	4	ed	ed	NNP
cord-010499-yefxrj30	160	5	(	(	-LRB-
cord-010499-yefxrj30	160	6	+	+	CC
cord-010499-yefxrj30	160	7	LME	LME	NNP
cord-010499-yefxrj30	160	8	)	)	-RRB-
cord-010499-yefxrj30	160	9	normalized	normalize	VBN
cord-010499-yefxrj30	160	10	to	to	IN
cord-010499-yefxrj30	160	11	unstarved	unstarved	JJ
cord-010499-yefxrj30	160	12	values	value	NNS
cord-010499-yefxrj30	160	13	.	.	.
cord-010499-yefxrj30	161	1	Fig	Fig	NNP
cord-010499-yefxrj30	161	2	.	.	.
cord-010499-yefxrj30	162	1	3	3	LS
cord-010499-yefxrj30	162	2	.	.	.
cord-010499-yefxrj30	163	1	The	the	DT
cord-010499-yefxrj30	163	2	protein	protein	NN
cord-010499-yefxrj30	163	3	sequence	sequence	NN
cord-010499-yefxrj30	163	4	Is	be	VBZ
cord-010499-yefxrj30	163	5	very	very	RB
cord-010499-yefxrj30	163	6	similar	similar	JJ
cord-010499-yefxrj30	163	7	to	to	IN
cord-010499-yefxrj30	163	8	that	that	DT
cord-010499-yefxrj30	163	9	of	of	IN
cord-010499-yefxrj30	163	10	the	the	DT
cord-010499-yefxrj30	163	11	protein	protein	NN
cord-010499-yefxrj30	163	12	from	from	IN
cord-010499-yefxrj30	163	13	unstarved	unstarved	JJ
cord-010499-yefxrj30	163	14	cells	cell	NNS
cord-010499-yefxrj30	163	15	(	(	-LRB-
cord-010499-yefxrj30	163	16	Fig	Fig	NNP
cord-010499-yefxrj30	163	17	.	.	NNP
cord-010499-yefxrj30	163	18	2	2	CD
cord-010499-yefxrj30	163	19	)	)	-RRB-
cord-010499-yefxrj30	163	20	,	,	,
cord-010499-yefxrj30	163	21	with	with	IN
cord-010499-yefxrj30	163	22	one	one	CD
cord-010499-yefxrj30	163	23	significant	significant	JJ
cord-010499-yefxrj30	163	24	exception	exception	NN
cord-010499-yefxrj30	163	25	.	.	.
cord-010499-yefxrj30	164	1	For	for	IN
cord-010499-yefxrj30	164	2	the	the	DT
cord-010499-yefxrj30	164	3	first	first	JJ
cord-010499-yefxrj30	164	4	nine	nine	CD
cord-010499-yefxrj30	164	5	cycles	cycle	NNS
cord-010499-yefxrj30	164	6	,	,	,
cord-010499-yefxrj30	164	7	the	the	DT
cord-010499-yefxrj30	164	8	initial	initial	JJ
cord-010499-yefxrj30	164	9	T	T	NNP
cord-010499-yefxrj30	164	10	-	-	HYPH
cord-010499-yefxrj30	164	11	M	M	NNP
cord-010499-yefxrj30	164	12	-	-	HYPH
cord-010499-yefxrj30	164	13	i	i	NNP
cord-010499-yefxrj30	164	14	-	-	HYPH
cord-010499-yefxrj30	164	15	T	T	NNP
cord-010499-yefxrj30	164	16	-	-	HYPH
cord-010499-yefxrj30	164	17	P	P	NNP
cord-010499-yefxrj30	164	18	-	-	HYPH
cord-010499-yefxrj30	164	19	S	S	NNP
cord-010499-yefxrj30	164	20	-	-	HYPH
cord-010499-yefxrj30	164	21	S	S	NNP
cord-010499-yefxrj30	164	22	-	-	HYPH
cord-010499-yefxrj30	164	23	N	N	NNP
cord-010499-yefxrj30	164	24	-	-	HYPH
cord-010499-yefxrj30	164	25	F	F	NNP
cord-010499-yefxrj30	164	26	sequence	sequence	NN
cord-010499-yefxrj30	164	27	of	of	IN
cord-010499-yefxrj30	164	28	the	the	DT
cord-010499-yefxrj30	164	29	noimal	noimal	JJ
cord-010499-yefxrj30	164	30	(	(	-LRB-
cord-010499-yefxrj30	164	31	0	0	NFP
cord-010499-yefxrj30	164	32	)	)	-RRB-
cord-010499-yefxrj30	164	33	reading	reading	NN
cord-010499-yefxrj30	164	34	frame	frame	NN
cord-010499-yefxrj30	164	35	is	be	VBZ
cord-010499-yefxrj30	164	36	clear	clear	JJ
cord-010499-yefxrj30	164	37	,	,	,
cord-010499-yefxrj30	164	38	as	as	IN
cord-010499-yefxrj30	164	39	It	-PRON-	PRP
cord-010499-yefxrj30	164	40	was	be	VBD
cord-010499-yefxrj30	164	41	in	in	IN
cord-010499-yefxrj30	164	42	the	the	DT
cord-010499-yefxrj30	164	43	protein	protein	NN
cord-010499-yefxrj30	164	44	from	from	IN
cord-010499-yefxrj30	164	45	unstarved	unstarved	NNP
cord-010499-yefxrj30	164	46	ceils	ceils	NNP
cord-010499-yefxrj30	164	47	.	.	.
cord-010499-yefxrj30	165	1	From	from	IN
cord-010499-yefxrj30	165	2	cycle	cycle	NN
cord-010499-yefxrj30	165	3	11	11	CD
cord-010499-yefxrj30	165	4	onwards	onwards	RB
cord-010499-yefxrj30	165	5	the	the	DT
cord-010499-yefxrj30	165	6	signature	signature	NN
cord-010499-yefxrj30	165	7	of	of	IN
cord-010499-yefxrj30	165	8	the	the	DT
cord-010499-yefxrj30	165	9	leftward	leftward	JJ
cord-010499-yefxrj30	165	10	reading	reading	NN
cord-010499-yefxrj30	165	11	frame	frame	NN
cord-010499-yefxrj30	165	12	,	,	,
cord-010499-yefxrj30	165	13	R	r	NN
cord-010499-yefxrj30	165	14	-	-	HYPH
cord-010499-yefxrj30	165	15	E	e	NN
cord-010499-yefxrj30	165	16	-	-	HYPH
cord-010499-yefxrj30	165	17	G	g	NN
cord-010499-yefxrj30	165	18	-	-	HYPH
cord-010499-yefxrj30	165	19	i	i	NN
cord-010499-yefxrj30	165	20	-	-	HYPH
cord-010499-yefxrj30	165	21	P	p	NN
cord-010499-yefxrj30	165	22	-	-	HYPH
cord-010499-yefxrj30	165	23	G	G	NNP
cord-010499-yefxrj30	165	24	,	,	,
cord-010499-yefxrj30	165	25	is	be	VBZ
cord-010499-yefxrj30	165	26	equaily	equaily	RB
cord-010499-yefxrj30	165	27	clear	clear	JJ
cord-010499-yefxrj30	165	28	.	.	.
cord-010499-yefxrj30	166	1	The	the	DT
cord-010499-yefxrj30	166	2	one	one	CD
cord-010499-yefxrj30	166	3	difference	difference	NN
cord-010499-yefxrj30	166	4	between	between	IN
cord-010499-yefxrj30	166	5	the	the	DT
cord-010499-yefxrj30	166	6	starved	starved	JJ
cord-010499-yefxrj30	166	7	and	and	CC
cord-010499-yefxrj30	166	8	unstarved	unstarved	JJ
cord-010499-yefxrj30	166	9	proteins	protein	NNS
cord-010499-yefxrj30	166	10	is	be	VBZ
cord-010499-yefxrj30	166	11	at	at	IN
cord-010499-yefxrj30	166	12	cycle	cycle	NN
cord-010499-yefxrj30	166	13	10	10	CD
cord-010499-yefxrj30	166	14	,	,	,
cord-010499-yefxrj30	166	15	the	the	DT
cord-010499-yefxrj30	166	16	position	position	NN
cord-010499-yefxrj30	166	17	of	of	IN
cord-010499-yefxrj30	166	18	the	the	DT
cord-010499-yefxrj30	166	19	leucine	leucine	NN
cord-010499-yefxrj30	166	20	codon	codon	NN
cord-010499-yefxrj30	166	21	.	.	.
cord-010499-yefxrj30	167	1	The	the	DT
cord-010499-yefxrj30	167	2	predominant	predominant	JJ
cord-010499-yefxrj30	167	3	amino	amino	NN
cord-010499-yefxrj30	167	4	acid	acid	NN
cord-010499-yefxrj30	167	5	in	in	IN
cord-010499-yefxrj30	167	6	the	the	DT
cord-010499-yefxrj30	167	7	starved	starved	JJ
cord-010499-yefxrj30	167	8	protein	protein	NN
cord-010499-yefxrj30	167	9	is	be	VBZ
cord-010499-yefxrj30	167	10	F	F	NNP
cord-010499-yefxrj30	167	11	(	(	-LRB-
cord-010499-yefxrj30	167	12	phenyialanine	phenyialanine	NN
cord-010499-yefxrj30	167	13	)	)	-RRB-
cord-010499-yefxrj30	167	14	rather	rather	RB
cord-010499-yefxrj30	167	15	than	than	IN
cord-010499-yefxrj30	167	16	L	L	NNP
cord-010499-yefxrj30	167	17	at	at	IN
cord-010499-yefxrj30	167	18	this	this	DT
cord-010499-yefxrj30	167	19	position	position	NN
cord-010499-yefxrj30	167	20	.	.	.
cord-010499-yefxrj30	168	1	Three	three	CD
cord-010499-yefxrj30	168	2	considerations	consideration	NNS
cord-010499-yefxrj30	168	3	argue	argue	VBP
cord-010499-yefxrj30	168	4	that	that	IN
cord-010499-yefxrj30	168	5	carryover	carryover	NN
cord-010499-yefxrj30	168	6	of	of	IN
cord-010499-yefxrj30	168	7	F	F	NNP
cord-010499-yefxrj30	168	8	from	from	IN
cord-010499-yefxrj30	168	9	cycle	cycle	NN
cord-010499-yefxrj30	168	10	9	9	CD
cord-010499-yefxrj30	168	11	,	,	,
cord-010499-yefxrj30	168	12	the	the	DT
cord-010499-yefxrj30	168	13	preceding	precede	VBG
cord-010499-yefxrj30	168	14	position	position	NN
cord-010499-yefxrj30	168	15	,	,	,
cord-010499-yefxrj30	168	16	does	do	VBZ
cord-010499-yefxrj30	168	17	not	not	RB
cord-010499-yefxrj30	168	18	contribute	contribute	VB
cord-010499-yefxrj30	168	19	significantly	significantly	RB
cord-010499-yefxrj30	168	20	to	to	IN
cord-010499-yefxrj30	168	21	the	the	DT
cord-010499-yefxrj30	168	22	peak	peak	NN
cord-010499-yefxrj30	168	23	of	of	IN
cord-010499-yefxrj30	168	24	F	F	NNP
cord-010499-yefxrj30	168	25	in	in	IN
cord-010499-yefxrj30	168	26	cycle	cycle	NNP
cord-010499-yefxrj30	168	27	10	10	CD
cord-010499-yefxrj30	168	28	of	of	IN
cord-010499-yefxrj30	168	29	the	the	DT
cord-010499-yefxrj30	168	30	leucine	leucine	NN
cord-010499-yefxrj30	168	31	-	-	HYPH
cord-010499-yefxrj30	168	32	starved	starve	VBN
cord-010499-yefxrj30	168	33	protein	protein	NN
cord-010499-yefxrj30	168	34	.	.	.
cord-010499-yefxrj30	169	1	First	first	RB
cord-010499-yefxrj30	169	2	,	,	,
cord-010499-yefxrj30	169	3	the	the	DT
cord-010499-yefxrj30	169	4	data	datum	NNS
cord-010499-yefxrj30	169	5	in	in	IN
cord-010499-yefxrj30	169	6	every	every	DT
cord-010499-yefxrj30	169	7	cycle	cycle	NN
cord-010499-yefxrj30	169	8	have	have	VBP
cord-010499-yefxrj30	169	9	been	be	VBN
cord-010499-yefxrj30	169	10	corrected	correct	VBN
cord-010499-yefxrj30	169	11	for	for	IN
cord-010499-yefxrj30	169	12	carryover	carryover	NN
cord-010499-yefxrj30	169	13	by	by	IN
cord-010499-yefxrj30	169	14	means	mean	NNS
cord-010499-yefxrj30	169	15	of	of	IN
cord-010499-yefxrj30	169	16	the	the	DT
cord-010499-yefxrj30	169	17	Applied	Applied	NNP
cord-010499-yefxrj30	169	18	Biosystems	Biosystems	NNP
cord-010499-yefxrj30	169	19	lagcorrection	lagcorrection	NN
cord-010499-yefxrj30	169	20	aigorithm	aigorithm	NNP
cord-010499-yefxrj30	169	21	(	(	-LRB-
cord-010499-yefxrj30	169	22	Huni^apiller	Huni^apiller	NNP
cord-010499-yefxrj30	169	23	,	,	,
cord-010499-yefxrj30	169	24	1986	1986	CD
cord-010499-yefxrj30	169	25	)	)	-RRB-
cord-010499-yefxrj30	169	26	.	.	.
cord-010499-yefxrj30	170	1	The	the	DT
cord-010499-yefxrj30	170	2	effectiveness	effectiveness	NN
cord-010499-yefxrj30	170	3	(	(	-LRB-
cord-010499-yefxrj30	170	4	3	3	CD
cord-010499-yefxrj30	170	5	)	)	-RRB-
cord-010499-yefxrj30	170	6	Exponential	exponential	JJ
cord-010499-yefxrj30	170	7	cells	cell	NNS
cord-010499-yefxrj30	170	8	carrying	carry	VBG
cord-010499-yefxrj30	170	9	plasmid	plasmid	NN
cord-010499-yefxrj30	170	10	pHIV201-U7	pHIV201-U7	NNP
cord-010499-yefxrj30	170	11	were	be	VBD
cord-010499-yefxrj30	170	12	treated	treat	VBN
cord-010499-yefxrj30	170	13	as	as	IN
cord-010499-yefxrj30	170	14	in	in	IN
cord-010499-yefxrj30	170	15	Table	Table	NNP
cord-010499-yefxrj30	170	16	3	3	CD
cord-010499-yefxrj30	170	17	.	.	.
cord-010499-yefxrj30	171	1	The	the	DT
cord-010499-yefxrj30	171	2	mean	mean	JJ
cord-010499-yefxrj30	171	3	control	control	NN
cord-010499-yefxrj30	171	4	differential	differential	JJ
cord-010499-yefxrj30	171	5	rate	rate	NN
cord-010499-yefxrj30	171	6	was	be	VBD
cord-010499-yefxrj30	171	7	4.7	4.7	CD
cord-010499-yefxrj30	171	8	±	±	CD
cord-010499-yefxrj30	171	9	0.20	0.20	CD
cord-010499-yefxrj30	171	10	(	(	-LRB-
cord-010499-yefxrj30	171	11	3	3	CD
cord-010499-yefxrj30	171	12	)	)	-RRB-
cord-010499-yefxrj30	171	13	.	.	.
cord-010499-yefxrj30	172	1	of	of	IN
cord-010499-yefxrj30	172	2	this	this	DT
cord-010499-yefxrj30	172	3	correction	correction	NN
cord-010499-yefxrj30	172	4	can	can	MD
cord-010499-yefxrj30	172	5	be	be	VB
cord-010499-yefxrj30	172	6	seen	see	VBN
cord-010499-yefxrj30	172	7	in	in	IN
cord-010499-yefxrj30	172	8	the	the	DT
cord-010499-yefxrj30	172	9	very	very	RB
cord-010499-yefxrj30	172	10	low	low	JJ
cord-010499-yefxrj30	172	11	levels	level	NNS
cord-010499-yefxrj30	172	12	of	of	IN
cord-010499-yefxrj30	172	13	carryover	carryover	NN
cord-010499-yefxrj30	172	14	throughout	throughout	IN
cord-010499-yefxrj30	172	15	the	the	DT
cord-010499-yefxrj30	172	16	cycle	cycle	NN
cord-010499-yefxrj30	172	17	bar	bar	NN
cord-010499-yefxrj30	172	18	plots	plot	NNS
cord-010499-yefxrj30	172	19	of	of	IN
cord-010499-yefxrj30	172	20	Figs	Figs	NNP
cord-010499-yefxrj30	172	21	2	2	CD
cord-010499-yefxrj30	172	22	and	and	CC
cord-010499-yefxrj30	172	23	3	3	CD
cord-010499-yefxrj30	172	24	,	,	,
cord-010499-yefxrj30	172	25	and	and	CC
cord-010499-yefxrj30	172	26	of	of	IN
cord-010499-yefxrj30	172	27	our	-PRON-	PRP$
cord-010499-yefxrj30	172	28	earlier	early	JJR
cord-010499-yefxrj30	172	29	publications	publication	NNS
cord-010499-yefxrj30	172	30	(	(	-LRB-
cord-010499-yefxrj30	172	31	Peter	Peter	NNP
cord-010499-yefxrj30	172	32	et	et	NNP
cord-010499-yefxrj30	172	33	ai	ai	NNP
cord-010499-yefxrj30	172	34	,	,	,
cord-010499-yefxrj30	172	35	1992	1992	CD
cord-010499-yefxrj30	172	36	;	;	:
cord-010499-yefxrj30	172	37	Gallant	Gallant	NNP
cord-010499-yefxrj30	172	38	and	and	CC
cord-010499-yefxrj30	172	39	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	172	40	,	,	,
cord-010499-yefxrj30	172	41	1992	1992	CD
cord-010499-yefxrj30	172	42	)	)	-RRB-
cord-010499-yefxrj30	172	43	.	.	.
cord-010499-yefxrj30	173	1	Second	second	JJ
cord-010499-yefxrj30	173	2	,	,	,
cord-010499-yefxrj30	173	3	amino	amino	JJ
cord-010499-yefxrj30	173	4	acids	acid	NNS
cord-010499-yefxrj30	173	5	differ	differ	VBP
cord-010499-yefxrj30	173	6	in	in	IN
cord-010499-yefxrj30	173	7	their	-PRON-	PRP$
cord-010499-yefxrj30	173	8	susceptibility	susceptibility	NN
cord-010499-yefxrj30	173	9	to	to	IN
cord-010499-yefxrj30	173	10	carryover	carryover	NN
cord-010499-yefxrj30	173	11	from	from	IN
cord-010499-yefxrj30	173	12	one	one	CD
cord-010499-yefxrj30	173	13	cycle	cycle	NN
cord-010499-yefxrj30	173	14	to	to	IN
cord-010499-yefxrj30	173	15	the	the	DT
cord-010499-yefxrj30	173	16	next	next	JJ
cord-010499-yefxrj30	174	1	(	(	-LRB-
cord-010499-yefxrj30	174	2	proline	proline	NNP
cord-010499-yefxrj30	174	3	,	,	,
cord-010499-yefxrj30	174	4	for	for	IN
cord-010499-yefxrj30	174	5	example	example	NN
cord-010499-yefxrj30	174	6	,	,	,
cord-010499-yefxrj30	174	7	being	be	VBG
cord-010499-yefxrj30	174	8	notoriously	notoriously	RB
cord-010499-yefxrj30	174	9	bad	bad	JJ
cord-010499-yefxrj30	174	10	)	)	-RRB-
cord-010499-yefxrj30	174	11	,	,	,
cord-010499-yefxrj30	174	12	and	and	CC
cord-010499-yefxrj30	174	13	it	-PRON-	PRP
cord-010499-yefxrj30	174	14	is	be	VBZ
cord-010499-yefxrj30	174	15	carryover	carryover	NN
cord-010499-yefxrj30	174	16	of	of	IN
cord-010499-yefxrj30	174	17	F	f	NN
cord-010499-yefxrj30	174	18	that	that	WDT
cord-010499-yefxrj30	174	19	we	-PRON-	PRP
cord-010499-yefxrj30	174	20	need	need	VBP
cord-010499-yefxrj30	174	21	to	to	TO
cord-010499-yefxrj30	174	22	assess	assess	VB
cord-010499-yefxrj30	174	23	in	in	IN
cord-010499-yefxrj30	174	24	considering	consider	VBG
cord-010499-yefxrj30	174	25	these	these	DT
cord-010499-yefxrj30	174	26	data	datum	NNS
cord-010499-yefxrj30	174	27	.	.	.
cord-010499-yefxrj30	175	1	In	in	IN
cord-010499-yefxrj30	175	2	fact	fact	NN
cord-010499-yefxrj30	175	3	.	.	.
cord-010499-yefxrj30	176	1	Figs	fig	NNS
cord-010499-yefxrj30	176	2	6	6	CD
cord-010499-yefxrj30	176	3	and	and	CC
cord-010499-yefxrj30	176	4	7	7	CD
cord-010499-yefxrj30	176	5	of	of	IN
cord-010499-yefxrj30	176	6	Gallant	Gallant	NNP
cord-010499-yefxrj30	176	7	and	and	CC
cord-010499-yefxrj30	176	8	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	176	9	(	(	-LRB-
cord-010499-yefxrj30	176	10	1992	1992	CD
cord-010499-yefxrj30	176	11	)	)	-RRB-
cord-010499-yefxrj30	176	12	present	present	VBP
cord-010499-yefxrj30	176	13	exactly	exactly	RB
cord-010499-yefxrj30	176	14	the	the	DT
cord-010499-yefxrj30	176	15	needed	need	VBN
cord-010499-yefxrj30	176	16	controi	controi	NN
cord-010499-yefxrj30	176	17	:	:	:
cord-010499-yefxrj30	177	1	F	F	NNP
cord-010499-yefxrj30	177	2	was	be	VBD
cord-010499-yefxrj30	177	3	the	the	DT
cord-010499-yefxrj30	177	4	amino	amino	NN
cord-010499-yefxrj30	177	5	acid	acid	NN
cord-010499-yefxrj30	177	6	present	present	JJ
cord-010499-yefxrj30	177	7	in	in	IN
cord-010499-yefxrj30	177	8	cycle	cycle	NN
cord-010499-yefxrj30	177	9	7	7	CD
cord-010499-yefxrj30	177	10	of	of	IN
cord-010499-yefxrj30	177	11	both	both	DT
cord-010499-yefxrj30	177	12	sequences	sequence	NNS
cord-010499-yefxrj30	177	13	,	,	,
cord-010499-yefxrj30	177	14	and	and	CC
cord-010499-yefxrj30	177	15	cycle	cycle	NN
cord-010499-yefxrj30	177	16	8	8	CD
cord-010499-yefxrj30	177	17	corresponded	correspond	VBD
cord-010499-yefxrj30	177	18	to	to	IN
cord-010499-yefxrj30	177	19	a	a	DT
cord-010499-yefxrj30	177	20	'	'	``
cord-010499-yefxrj30	177	21	hungry	hungry	JJ
cord-010499-yefxrj30	177	22	'	'	''
cord-010499-yefxrj30	177	23	codon	codon	NN
cord-010499-yefxrj30	177	24	,	,	,
cord-010499-yefxrj30	177	25	just	just	RB
cord-010499-yefxrj30	177	26	as	as	IN
cord-010499-yefxrj30	177	27	in	in	IN
cord-010499-yefxrj30	177	28	the	the	DT
cord-010499-yefxrj30	177	29	present	present	JJ
cord-010499-yefxrj30	177	30	case	case	NN
cord-010499-yefxrj30	177	31	.	.	.
cord-010499-yefxrj30	178	1	In	in	IN
cord-010499-yefxrj30	178	2	those	those	DT
cord-010499-yefxrj30	178	3	two	two	CD
cord-010499-yefxrj30	178	4	sets	set	NNS
cord-010499-yefxrj30	178	5	of	of	IN
cord-010499-yefxrj30	178	6	data	datum	NNS
cord-010499-yefxrj30	178	7	,	,	,
cord-010499-yefxrj30	178	8	which	which	WDT
cord-010499-yefxrj30	178	9	represent	represent	VBP
cord-010499-yefxrj30	178	10	the	the	DT
cord-010499-yefxrj30	178	11	average	average	NN
cord-010499-yefxrj30	178	12	of	of	IN
cord-010499-yefxrj30	178	13	four	four	CD
cord-010499-yefxrj30	178	14	independent	independent	JJ
cord-010499-yefxrj30	178	15	sequencing	sequencing	NN
cord-010499-yefxrj30	178	16	runs	run	NNS
cord-010499-yefxrj30	178	17	in	in	IN
cord-010499-yefxrj30	178	18	each	each	DT
cord-010499-yefxrj30	178	19	case	case	NN
cord-010499-yefxrj30	178	20	,	,	,
cord-010499-yefxrj30	178	21	carryover	carryover	NN
cord-010499-yefxrj30	178	22	of	of	IN
cord-010499-yefxrj30	178	23	F	F	NNP
cord-010499-yefxrj30	178	24	from	from	IN
cord-010499-yefxrj30	178	25	cycle	cycle	NN
cord-010499-yefxrj30	178	26	7	7	CD
cord-010499-yefxrj30	178	27	to	to	IN
cord-010499-yefxrj30	178	28	the	the	DT
cord-010499-yefxrj30	178	29	next	next	JJ
cord-010499-yefxrj30	178	30	cycle	cycle	NN
cord-010499-yefxrj30	178	31	averaged	average	VBD
cord-010499-yefxrj30	178	32	8.3	8.3	CD
cord-010499-yefxrj30	178	33	%	%	NN
cord-010499-yefxrj30	178	34	(	(	-LRB-
cord-010499-yefxrj30	178	35	standard	standard	JJ
cord-010499-yefxrj30	178	36	error	error	NN
cord-010499-yefxrj30	178	37	=	=	SYM
cord-010499-yefxrj30	178	38	2.8	2.8	CD
cord-010499-yefxrj30	178	39	%	%	NN
cord-010499-yefxrj30	178	40	)	)	-RRB-
cord-010499-yefxrj30	178	41	,	,	,
cord-010499-yefxrj30	178	42	far	far	RB
cord-010499-yefxrj30	178	43	less	less	JJR
cord-010499-yefxrj30	178	44	than	than	IN
cord-010499-yefxrj30	178	45	the	the	DT
cord-010499-yefxrj30	178	46	relative	relative	JJ
cord-010499-yefxrj30	178	47	ievel	ievel	NN
cord-010499-yefxrj30	178	48	of	of	IN
cord-010499-yefxrj30	178	49	F	F	NNP
cord-010499-yefxrj30	178	50	found	find	VBD
cord-010499-yefxrj30	178	51	in	in	IN
cord-010499-yefxrj30	178	52	cycle	cycle	NN
cord-010499-yefxrj30	178	53	10	10	CD
cord-010499-yefxrj30	178	54	of	of	IN
cord-010499-yefxrj30	178	55	the	the	DT
cord-010499-yefxrj30	178	56	present	present	JJ
cord-010499-yefxrj30	178	57	cycle	cycle	NN
cord-010499-yefxrj30	178	58	bar	bar	NN
cord-010499-yefxrj30	178	59	plots	plot	NNS
cord-010499-yefxrj30	178	60	.	.	.
cord-010499-yefxrj30	179	1	Finally	finally	RB
cord-010499-yefxrj30	179	2	,	,	,
cord-010499-yefxrj30	179	3	the	the	DT
cord-010499-yefxrj30	179	4	starved	starved	JJ
cord-010499-yefxrj30	179	5	and	and	CC
cord-010499-yefxrj30	179	6	unstarved	unstarved	JJ
cord-010499-yefxrj30	179	7	proteins	protein	NNS
cord-010499-yefxrj30	179	8	are	be	VBP
cord-010499-yefxrj30	179	9	virtually	virtually	RB
cord-010499-yefxrj30	179	10	identical	identical	JJ
cord-010499-yefxrj30	179	11	at	at	IN
cord-010499-yefxrj30	179	12	every	every	DT
cord-010499-yefxrj30	179	13	position	position	NN
cord-010499-yefxrj30	179	14	except	except	IN
cord-010499-yefxrj30	179	15	cycle	cycle	NN
cord-010499-yefxrj30	179	16	10	10	CD
cord-010499-yefxrj30	179	17	,	,	,
cord-010499-yefxrj30	179	18	in	in	IN
cord-010499-yefxrj30	179	19	which	which	WDT
cord-010499-yefxrj30	179	20	the	the	DT
cord-010499-yefxrj30	179	21	difference	difference	NN
cord-010499-yefxrj30	179	22	in	in	IN
cord-010499-yefxrj30	179	23	regard	regard	NN
cord-010499-yefxrj30	179	24	to	to	IN
cord-010499-yefxrj30	179	25	phenylaianine	phenylaianine	NN
cord-010499-yefxrj30	179	26	and	and	CC
cord-010499-yefxrj30	179	27	leucine	leucine	NNP
cord-010499-yefxrj30	179	28	was	be	VBD
cord-010499-yefxrj30	179	29	replicated	replicate	VBN
cord-010499-yefxrj30	179	30	in	in	IN
cord-010499-yefxrj30	179	31	several	several	JJ
cord-010499-yefxrj30	179	32	independent	independent	JJ
cord-010499-yefxrj30	179	33	sequencing	sequencing	NN
cord-010499-yefxrj30	179	34	runs	run	NNS
cord-010499-yefxrj30	179	35	on	on	IN
cord-010499-yefxrj30	179	36	protein	protein	NN
cord-010499-yefxrj30	179	37	of	of	IN
cord-010499-yefxrj30	179	38	each	each	DT
cord-010499-yefxrj30	179	39	type	type	NN
cord-010499-yefxrj30	179	40	.	.	.
cord-010499-yefxrj30	180	1	A	a	DT
cord-010499-yefxrj30	180	2	summary	summary	NN
cord-010499-yefxrj30	180	3	of	of	IN
cord-010499-yefxrj30	180	4	this	this	DT
cord-010499-yefxrj30	180	5	comparison	comparison	NN
cord-010499-yefxrj30	180	6	of	of	IN
cord-010499-yefxrj30	180	7	the	the	DT
cord-010499-yefxrj30	180	8	starved	starved	JJ
cord-010499-yefxrj30	180	9	and	and	CC
cord-010499-yefxrj30	180	10	unstarved	unstarved	JJ
cord-010499-yefxrj30	180	11	proteins	protein	NNS
cord-010499-yefxrj30	180	12	in	in	IN
cord-010499-yefxrj30	180	13	and	and	CC
cord-010499-yefxrj30	180	14	around	around	IN
cord-010499-yefxrj30	180	15	cycle	cycle	NN
cord-010499-yefxrj30	180	16	10	10	CD
cord-010499-yefxrj30	180	17	,	,	,
cord-010499-yefxrj30	180	18	and	and	CC
cord-010499-yefxrj30	180	19	the	the	DT
cord-010499-yefxrj30	180	20	statistics	statistic	NNS
cord-010499-yefxrj30	180	21	for	for	IN
cord-010499-yefxrj30	180	22	this	this	DT
cord-010499-yefxrj30	180	23	cycle	cycle	NN
cord-010499-yefxrj30	180	24	,	,	,
cord-010499-yefxrj30	180	25	are	be	VBP
cord-010499-yefxrj30	180	26	presented	present	VBN
cord-010499-yefxrj30	180	27	In	in	IN
cord-010499-yefxrj30	180	28	Fig	Fig	NNP
cord-010499-yefxrj30	180	29	.	.	.
cord-010499-yefxrj30	181	1	4	4	LS
cord-010499-yefxrj30	181	2	.	.	.
cord-010499-yefxrj30	182	1	Phenylaianine	Phenylaianine	NNP
cord-010499-yefxrj30	182	2	corresponds	correspond	VBZ
cord-010499-yefxrj30	182	3	to	to	IN
cord-010499-yefxrj30	182	4	the	the	DT
cord-010499-yefxrj30	182	5	UUU	UUU	NNP
cord-010499-yefxrj30	182	6	triplet	triplet	NN
cord-010499-yefxrj30	182	7	overlapping	overlap	VBG
cord-010499-yefxrj30	182	8	the	the	DT
cord-010499-yefxrj30	182	9	hungry	hungry	JJ
cord-010499-yefxrj30	182	10	ieucine	ieucine	NN
cord-010499-yefxrj30	182	11	codon	codon	NN
cord-010499-yefxrj30	182	12	in	in	IN
cord-010499-yefxrj30	182	13	the	the	DT
cord-010499-yefxrj30	182	14	leftward	leftward	JJ
cord-010499-yefxrj30	182	15	reading	reading	NN
cord-010499-yefxrj30	182	16	frame	frame	NN
cord-010499-yefxrj30	182	17	.	.	.
cord-010499-yefxrj30	183	1	We	-PRON-	PRP
cord-010499-yefxrj30	183	2	conclude	conclude	VBP
cord-010499-yefxrj30	183	3	that	that	IN
cord-010499-yefxrj30	183	4	most	most	JJS
cord-010499-yefxrj30	183	5	ribosomes	ribosome	NNS
cord-010499-yefxrj30	183	6	which	which	WDT
cord-010499-yefxrj30	183	7	produced	produce	VBD
cord-010499-yefxrj30	183	8	P	p	NN
cord-010499-yefxrj30	183	9	-	-	HYPH
cord-010499-yefxrj30	183	10	galactosidase	galactosidase	NN
cord-010499-yefxrj30	183	11	slipped	slip	VBD
cord-010499-yefxrj30	183	12	ieftward	ieftward	NN
cord-010499-yefxrj30	183	13	when	when	WRB
cord-010499-yefxrj30	183	14	stalled	stall	VBN
cord-010499-yefxrj30	183	15	at	at	IN
cord-010499-yefxrj30	183	16	the	the	DT
cord-010499-yefxrj30	183	17	leucine	leucine	NN
cord-010499-yefxrj30	183	18	codon	codon	NN
cord-010499-yefxrj30	183	19	before	before	IN
cord-010499-yefxrj30	183	20	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	183	21	-	-	HYPH
cord-010499-yefxrj30	183	22	tRNA	trna	NN
cord-010499-yefxrj30	183	23	binding	binding	NN
cord-010499-yefxrj30	183	24	,	,	,
cord-010499-yefxrj30	183	25	and	and	CC
cord-010499-yefxrj30	183	26	then	then	RB
cord-010499-yefxrj30	183	27	bound	bind	VBN
cord-010499-yefxrj30	183	28	phe	phe	NNP
cord-010499-yefxrj30	183	29	-	-	HYPH
cord-010499-yefxrj30	183	30	tRNA	trna	NN
cord-010499-yefxrj30	183	31	cognate	cognate	NN
cord-010499-yefxrj30	183	32	to	to	IN
cord-010499-yefxrj30	183	33	the	the	DT
cord-010499-yefxrj30	183	34	overlapping	overlap	VBG
cord-010499-yefxrj30	183	35	phenylaianine	phenylaianine	NN
cord-010499-yefxrj30	183	36	codon	codon	NN
cord-010499-yefxrj30	183	37	.	.	.
cord-010499-yefxrj30	184	1	However	however	RB
cord-010499-yefxrj30	184	2	,	,	,
cord-010499-yefxrj30	184	3	cycle	cycle	VB
cord-010499-yefxrj30	184	4	10	10	CD
cord-010499-yefxrj30	184	5	contains	contain	VBZ
cord-010499-yefxrj30	184	6	a	a	DT
cord-010499-yefxrj30	184	7	significant	significant	JJ
cord-010499-yefxrj30	184	8	secondary	secondary	JJ
cord-010499-yefxrj30	184	9	peak	peak	NN
cord-010499-yefxrj30	184	10	of	of	IN
cord-010499-yefxrj30	184	11	leucine	leucine	NN
cord-010499-yefxrj30	184	12	as	as	RB
cord-010499-yefxrj30	184	13	well	well	RB
cord-010499-yefxrj30	184	14	,	,	,
cord-010499-yefxrj30	184	15	suggesting	suggest	VBG
cord-010499-yefxrj30	184	16	that	that	IN
cord-010499-yefxrj30	184	17	a	a	DT
cord-010499-yefxrj30	184	18	minority	minority	NN
cord-010499-yefxrj30	184	19	of	of	IN
cord-010499-yefxrj30	184	20	ribosomes	ribosome	NNS
cord-010499-yefxrj30	184	21	bound	bind	VBN
cord-010499-yefxrj30	184	22	leucyl	leucyl	NNP
cord-010499-yefxrj30	184	23	-	-	HYPH
cord-010499-yefxrj30	184	24	tRNA	tRNA	NNP
cord-010499-yefxrj30	184	25	and	and	CC
cord-010499-yefxrj30	184	26	then	then	RB
cord-010499-yefxrj30	184	27	shifted	shift	VBD
cord-010499-yefxrj30	184	28	left	leave	VBN
cord-010499-yefxrj30	184	29	,	,	,
cord-010499-yefxrj30	184	30	just	just	RB
cord-010499-yefxrj30	184	31	as	as	IN
cord-010499-yefxrj30	184	32	in	in	IN
cord-010499-yefxrj30	184	33	unstarved	unstarved	JJ
cord-010499-yefxrj30	184	34	cells	cell	NNS
cord-010499-yefxrj30	184	35	.	.	.
cord-010499-yefxrj30	185	1	Our	-PRON-	PRP$
cord-010499-yefxrj30	185	2	wild	wild	JJ
cord-010499-yefxrj30	185	3	type	type	NN
cord-010499-yefxrj30	185	4	lacZ	lacz	XX
cord-010499-yefxrj30	186	1	*	*	NFP
cord-010499-yefxrj30	186	2	controi	controi	NNP
cord-010499-yefxrj30	186	3	shows	show	VBZ
cord-010499-yefxrj30	186	4	a	a	DT
cord-010499-yefxrj30	186	5	marked	marked	JJ
cord-010499-yefxrj30	186	6	decrease	decrease	NN
cord-010499-yefxrj30	186	7	in	in	IN
cord-010499-yefxrj30	186	8	p	p	NN
cord-010499-yefxrj30	186	9	-	-	HYPH
cord-010499-yefxrj30	186	10	galactosidase	galactosidase	NN
cord-010499-yefxrj30	186	11	synthesis	synthesis	NN
cord-010499-yefxrj30	186	12	during	during	IN
cord-010499-yefxrj30	186	13	limitation	limitation	NN
cord-010499-yefxrj30	186	14	for	for	IN
cord-010499-yefxrj30	186	15	each	each	DT
cord-010499-yefxrj30	186	16	of	of	IN
cord-010499-yefxrj30	186	17	tiie	tiie	NN
cord-010499-yefxrj30	186	18	amino	amino	JJ
cord-010499-yefxrj30	186	19	acids	acid	NNS
cord-010499-yefxrj30	186	20	tested	test	VBN
cord-010499-yefxrj30	186	21	.	.	.
cord-010499-yefxrj30	187	1	This	this	DT
cord-010499-yefxrj30	187	2	response	response	NN
cord-010499-yefxrj30	187	3	is	be	VBZ
cord-010499-yefxrj30	187	4	typical	typical	JJ
cord-010499-yefxrj30	187	5	of	of	IN
cord-010499-yefxrj30	187	6	relA	relA	NNS
cord-010499-yefxrj30	187	7	~	~	NFP
cord-010499-yefxrj30	187	8	cells	cell	NNS
cord-010499-yefxrj30	187	9	,	,	,
cord-010499-yefxrj30	187	10	and	and	CC
cord-010499-yefxrj30	187	11	is	be	VBZ
cord-010499-yefxrj30	187	12	primarily	primarily	RB
cord-010499-yefxrj30	187	13	caused	cause	VBN
cord-010499-yefxrj30	187	14	by	by	IN
cord-010499-yefxrj30	187	15	a	a	DT
cord-010499-yefxrj30	187	16	dependence	dependence	NN
cord-010499-yefxrj30	187	17	of	of	IN
cord-010499-yefxrj30	187	18	/acZtranscription	/acztranscription	CD
cord-010499-yefxrj30	187	19	on	on	IN
cord-010499-yefxrj30	187	20	ppGpp	ppGpp	NNP
cord-010499-yefxrj30	187	21	during	during	IN
cord-010499-yefxrj30	187	22	amino	amino	JJ
cord-010499-yefxrj30	187	23	acid	acid	NN
cord-010499-yefxrj30	187	24	limitation	limitation	NN
cord-010499-yefxrj30	187	25	(	(	-LRB-
cord-010499-yefxrj30	187	26	Primakoff	Primakoff	NNP
cord-010499-yefxrj30	187	27	and	and	CC
cord-010499-yefxrj30	187	28	Artz	Artz	NNP
cord-010499-yefxrj30	187	29	,	,	,
cord-010499-yefxrj30	187	30	1979	1979	CD
cord-010499-yefxrj30	187	31	;	;	:
cord-010499-yefxrj30	187	32	Yangefa/.	Yangefa/.	NNP
cord-010499-yefxrj30	187	33	,	,	,
cord-010499-yefxrj30	187	34	1979	1979	CD
cord-010499-yefxrj30	187	35	;	;	:
cord-010499-yefxrj30	187	36	Primakoff	Primakoff	NNP
cord-010499-yefxrj30	187	37	,	,	,
cord-010499-yefxrj30	187	38	1981	1981	CD
cord-010499-yefxrj30	187	39	;	;	:
cord-010499-yefxrj30	187	40	Foieyefa/.	Foieyefa/.	NNP
cord-010499-yefxrj30	187	41	,	,	,
cord-010499-yefxrj30	187	42	1982	1982	CD
cord-010499-yefxrj30	187	43	)	)	-RRB-
cord-010499-yefxrj30	187	44	,	,	,
cord-010499-yefxrj30	187	45	compounded	compound	VBN
cord-010499-yefxrj30	187	46	by	by	IN
cord-010499-yefxrj30	187	47	errors	error	NNS
cord-010499-yefxrj30	187	48	in	in	IN
cord-010499-yefxrj30	187	49	transiation	transiation	NN
cord-010499-yefxrj30	187	50	at	at	IN
cord-010499-yefxrj30	187	51	some	some	DT
cord-010499-yefxrj30	187	52	hungry	hungry	JJ
cord-010499-yefxrj30	187	53	codons	codon	NNS
cord-010499-yefxrj30	187	54	(	(	-LRB-
cord-010499-yefxrj30	187	55	reviewed	review	VBN
cord-010499-yefxrj30	187	56	by	by	IN
cord-010499-yefxrj30	187	57	Gallant	Gallant	NNP
cord-010499-yefxrj30	187	58	,	,	,
cord-010499-yefxrj30	187	59	1979	1979	CD
cord-010499-yefxrj30	187	60	;	;	:
cord-010499-yefxrj30	187	61	Cashe	Cashe	NNP
cord-010499-yefxrj30	187	62	!	!	.
cord-010499-yefxrj30	187	63	and	and	CC
cord-010499-yefxrj30	187	64	Rudd	Rudd	NNP
cord-010499-yefxrj30	187	65	,	,	,
cord-010499-yefxrj30	187	66	1987	1987	CD
cord-010499-yefxrj30	187	67	;	;	:
cord-010499-yefxrj30	187	68	Parker	Parker	NNP
cord-010499-yefxrj30	187	69	,	,	,
cord-010499-yefxrj30	187	70	1989	1989	CD
cord-010499-yefxrj30	187	71	)	)	-RRB-
cord-010499-yefxrj30	187	72	.	.	.
cord-010499-yefxrj30	188	1	Expression	expression	NN
cord-010499-yefxrj30	188	2	of	of	IN
cord-010499-yefxrj30	188	3	the	the	DT
cord-010499-yefxrj30	188	4	/acZ	/acZ	NNP
cord-010499-yefxrj30	188	5	gene	gene	NN
cord-010499-yefxrj30	188	6	carrying	carry	VBG
cord-010499-yefxrj30	188	7	the	the	DT
cord-010499-yefxrj30	188	8	HIV	HIV	NNP
cord-010499-yefxrj30	188	9	frameshift	frameshift	NN
cord-010499-yefxrj30	188	10	signal	signal	NN
cord-010499-yefxrj30	188	11	should	should	MD
cord-010499-yefxrj30	188	12	be	be	VB
cord-010499-yefxrj30	188	13	subject	subject	JJ
cord-010499-yefxrj30	188	14	to	to	IN
cord-010499-yefxrj30	188	15	the	the	DT
cord-010499-yefxrj30	188	16	same	same	JJ
cord-010499-yefxrj30	188	17	relA~	rela~	NN
cord-010499-yefxrj30	188	18	defects	defect	NNS
cord-010499-yefxrj30	188	19	and	and	CC
cord-010499-yefxrj30	188	20	is	be	VBZ
cord-010499-yefxrj30	188	21	indeed	indeed	RB
cord-010499-yefxrj30	188	22	reduced	reduce	VBN
cord-010499-yefxrj30	188	23	to	to	IN
cord-010499-yefxrj30	188	24	the	the	DT
cord-010499-yefxrj30	188	25	same	same	JJ
cord-010499-yefxrj30	188	26	extent	extent	NN
cord-010499-yefxrj30	188	27	as	as	IN
cord-010499-yefxrj30	188	28	wild	wild	JJ
cord-010499-yefxrj30	188	29	-	-	HYPH
cord-010499-yefxrj30	188	30	type	type	NN
cord-010499-yefxrj30	188	31	during	during	IN
cord-010499-yefxrj30	188	32	limitation	limitation	NN
cord-010499-yefxrj30	188	33	for	for	IN
cord-010499-yefxrj30	188	34	arginine	arginine	NN
cord-010499-yefxrj30	188	35	or	or	CC
cord-010499-yefxrj30	188	36	for	for	IN
cord-010499-yefxrj30	188	37	phenyialanyl	phenyialanyl	NNP
cord-010499-yefxrj30	188	38	-	-	HYPH
cord-010499-yefxrj30	188	39	tRNA	trna	NN
cord-010499-yefxrj30	188	40	(	(	-LRB-
cord-010499-yefxrj30	188	41	Table	Table	NNP
cord-010499-yefxrj30	188	42	2	2	CD
cord-010499-yefxrj30	188	43	)	)	-RRB-
cord-010499-yefxrj30	188	44	.	.	.
cord-010499-yefxrj30	189	1	During	during	IN
cord-010499-yefxrj30	189	2	(	(	-LRB-
cord-010499-yefxrj30	189	3	eucine	eucine	JJ
cord-010499-yefxrj30	189	4	limitation	limitation	NN
cord-010499-yefxrj30	189	5	,	,	,
cord-010499-yefxrj30	189	6	in	in	IN
cord-010499-yefxrj30	189	7	contrast	contrast	NN
cord-010499-yefxrj30	189	8	,	,	,
cord-010499-yefxrj30	189	9	enzyme	enzyme	NN
cord-010499-yefxrj30	189	10	synthesis	synthesis	NN
cord-010499-yefxrj30	189	11	is	be	VBZ
cord-010499-yefxrj30	189	12	increased	increase	VBN
cord-010499-yefxrj30	189	13	rather	rather	RB
cord-010499-yefxrj30	189	14	than	than	IN
cord-010499-yefxrj30	189	15	decreased	decrease	VBD
cord-010499-yefxrj30	189	16	in	in	IN
cord-010499-yefxrj30	189	17	cells	cell	NNS
cord-010499-yefxrj30	189	18	carrying	carry	VBG
cord-010499-yefxrj30	189	19	the	the	DT
cord-010499-yefxrj30	189	20	frameshift	frameshift	NN
cord-010499-yefxrj30	189	21	allele	allele	NN
cord-010499-yefxrj30	189	22	pHIV201	pHIV201	NNP
cord-010499-yefxrj30	190	1	(	(	-LRB-
cord-010499-yefxrj30	190	2	Table	table	NN
cord-010499-yefxrj30	190	3	3	3	CD
cord-010499-yefxrj30	190	4	)	)	-RRB-
cord-010499-yefxrj30	190	5	.	.	.
cord-010499-yefxrj30	191	1	In	in	IN
cord-010499-yefxrj30	191	2	201-U7	201-u7	CD
cord-010499-yefxrj30	191	3	,	,	,
cord-010499-yefxrj30	191	4	which	which	WDT
cord-010499-yefxrj30	191	5	is	be	VBZ
cord-010499-yefxrj30	191	6	identical	identical	JJ
cord-010499-yefxrj30	191	7	to	to	IN
cord-010499-yefxrj30	191	8	201	201	CD
cord-010499-yefxrj30	191	9	except	except	IN
cord-010499-yefxrj30	191	10	for	for	IN
cord-010499-yefxrj30	191	11	the	the	DT
cord-010499-yefxrj30	191	12	absence	absence	NN
cord-010499-yefxrj30	191	13	of	of	IN
cord-010499-yefxrj30	191	14	the	the	DT
cord-010499-yefxrj30	191	15	leucine	leucine	NN
cord-010499-yefxrj30	191	16	codon	codon	NN
cord-010499-yefxrj30	191	17	at	at	IN
cord-010499-yefxrj30	191	18	the	the	DT
cord-010499-yefxrj30	191	19	frameshift	frameshift	NN
cord-010499-yefxrj30	191	20	site	site	NN
cord-010499-yefxrj30	191	21	,	,	,
cord-010499-yefxrj30	191	22	leucine	leucine	NN
cord-010499-yefxrj30	191	23	limitation	limitation	NN
cord-010499-yefxrj30	191	24	provokes	provoke	VBZ
cord-010499-yefxrj30	191	25	a	a	DT
cord-010499-yefxrj30	191	26	decrease	decrease	NN
cord-010499-yefxrj30	191	27	in	in	IN
cord-010499-yefxrj30	191	28	enzyme	enzyme	NN
cord-010499-yefxrj30	191	29	synthesis	synthesis	NN
cord-010499-yefxrj30	191	30	(	(	-LRB-
cord-010499-yefxrj30	191	31	Table	Table	NNP
cord-010499-yefxrj30	191	32	4	4	CD
cord-010499-yefxrj30	191	33	)	)	-RRB-
cord-010499-yefxrj30	191	34	,	,	,
cord-010499-yefxrj30	191	35	as	as	IN
cord-010499-yefxrj30	191	36	it	-PRON-	PRP
cord-010499-yefxrj30	191	37	does	do	VBZ
cord-010499-yefxrj30	191	38	in	in	IN
cord-010499-yefxrj30	191	39	the	the	DT
cord-010499-yefxrj30	191	40	iacZ	iacZ	NNS
cord-010499-yefxrj30	191	41	*	*	NFP
cord-010499-yefxrj30	191	42	control	control	NN
cord-010499-yefxrj30	191	43	.	.	.
cord-010499-yefxrj30	192	1	The	the	DT
cord-010499-yefxrj30	192	2	fact	fact	NN
cord-010499-yefxrj30	192	3	that	that	IN
cord-010499-yefxrj30	192	4	enzyme	enzyme	VBZ
cord-010499-yefxrj30	192	5	synthesis	synthesis	NN
cord-010499-yefxrj30	192	6	increases	increase	NNS
cord-010499-yefxrj30	192	7	with	with	IN
cord-010499-yefxrj30	192	8	leucine	leucine	NN
cord-010499-yefxrj30	192	9	limitation	limitation	NN
cord-010499-yefxrj30	192	10	in	in	IN
cord-010499-yefxrj30	192	11	201	201	CD
cord-010499-yefxrj30	192	12	means	mean	VBZ
cord-010499-yefxrj30	192	13	that	that	IN
cord-010499-yefxrj30	192	14	an	an	DT
cord-010499-yefxrj30	192	15	increase	increase	NN
cord-010499-yefxrj30	192	16	in	in	IN
cord-010499-yefxrj30	192	17	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	192	18	more	more	RBR
cord-010499-yefxrj30	192	19	than	than	IN
cord-010499-yefxrj30	192	20	compensates	compensate	VBZ
cord-010499-yefxrj30	192	21	for	for	IN
cord-010499-yefxrj30	192	22	the	the	DT
cord-010499-yefxrj30	192	23	sharp	sharp	JJ
cord-010499-yefxrj30	192	24	decrease	decrease	NN
cord-010499-yefxrj30	192	25	in	in	IN
cord-010499-yefxrj30	192	26	lacZ	lacz	JJ
cord-010499-yefxrj30	192	27	expression	expression	NN
cord-010499-yefxrj30	192	28	found	find	VBN
cord-010499-yefxrj30	192	29	in	in	IN
cord-010499-yefxrj30	192	30	tine	tine	NN
cord-010499-yefxrj30	192	31	control	control	NN
cord-010499-yefxrj30	192	32	experiments	experiment	NNS
cord-010499-yefxrj30	192	33	with	with	IN
cord-010499-yefxrj30	192	34	the	the	DT
cord-010499-yefxrj30	192	35	wild	wild	JJ
cord-010499-yefxrj30	192	36	type	type	NN
cord-010499-yefxrj30	192	37	and	and	CC
cord-010499-yefxrj30	192	38	with	with	IN
cord-010499-yefxrj30	192	39	201-U7	201-u7	CD
cord-010499-yefxrj30	192	40	.	.	.
cord-010499-yefxrj30	193	1	The	the	DT
cord-010499-yefxrj30	193	2	increased	increase	VBN
cord-010499-yefxrj30	193	3	frameshifting	frameshifting	NN
cord-010499-yefxrj30	193	4	attributable	attributable	JJ
cord-010499-yefxrj30	193	5	to	to	IN
cord-010499-yefxrj30	193	6	this	this	DT
cord-010499-yefxrj30	193	7	one	one	CD
cord-010499-yefxrj30	193	8	leucine	leucine	NN
cord-010499-yefxrj30	193	9	codon	codon	NN
cord-010499-yefxrj30	193	10	can	can	MD
cord-010499-yefxrj30	193	11	be	be	VB
cord-010499-yefxrj30	193	12	estimated	estimate	VBN
cord-010499-yefxrj30	193	13	as	as	IN
cord-010499-yefxrj30	193	14	the	the	DT
cord-010499-yefxrj30	193	15	ratio	ratio	NN
cord-010499-yefxrj30	193	16	of	of	IN
cord-010499-yefxrj30	193	17	the	the	DT
cord-010499-yefxrj30	193	18	effect	effect	NN
cord-010499-yefxrj30	193	19	of	of	IN
cord-010499-yefxrj30	193	20	ieucine	ieucine	JJ
cord-010499-yefxrj30	193	21	limitation	limitation	NN
cord-010499-yefxrj30	193	22	on	on	IN
cord-010499-yefxrj30	193	23	201	201	CD
cord-010499-yefxrj30	193	24	to	to	IN
cord-010499-yefxrj30	193	25	that	that	DT
cord-010499-yefxrj30	193	26	on	on	IN
cord-010499-yefxrj30	193	27	201-U7	201-u7	CD
cord-010499-yefxrj30	193	28	.	.	.
cord-010499-yefxrj30	194	1	in	in	IN
cord-010499-yefxrj30	194	2	the	the	DT
cord-010499-yefxrj30	194	3	former	former	JJ
cord-010499-yefxrj30	194	4	case	case	NN
cord-010499-yefxrj30	194	5	,	,	,
cord-010499-yefxrj30	194	6	enzyme	enzyme	NN
cord-010499-yefxrj30	194	7	synthesis	synthesis	NN
cord-010499-yefxrj30	194	8	was	be	VBD
cord-010499-yefxrj30	194	9	two	two	CD
cord-010499-yefxrj30	194	10	times	time	NNS
cord-010499-yefxrj30	194	11	greater	great	JJR
cord-010499-yefxrj30	194	12	in	in	IN
cord-010499-yefxrj30	194	13	3)igmi	3)igmi	NNP
cord-010499-yefxrj30	194	14	"	"	''
cord-010499-yefxrj30	194	15	'	'	''
cord-010499-yefxrj30	194	16	of	of	IN
cord-010499-yefxrj30	194	17	leucinemethyl	leucinemethyl	NN
cord-010499-yefxrj30	194	18	-	-	HYPH
cord-010499-yefxrj30	194	19	ester	ester	NN
cord-010499-yefxrj30	194	20	than	than	IN
cord-010499-yefxrj30	194	21	in	in	IN
cord-010499-yefxrj30	194	22	leucine	leucine	NN
cord-010499-yefxrj30	194	23	,	,	,
cord-010499-yefxrj30	194	24	whereas	whereas	IN
cord-010499-yefxrj30	194	25	in	in	IN
cord-010499-yefxrj30	194	26	the	the	DT
cord-010499-yefxrj30	194	27	tter	tter	NNP
cord-010499-yefxrj30	194	28	case	case	NN
cord-010499-yefxrj30	194	29	it	-PRON-	PRP
cord-010499-yefxrj30	194	30	was	be	VBD
cord-010499-yefxrj30	194	31	three	three	CD
cord-010499-yefxrj30	194	32	times	time	NNS
cord-010499-yefxrj30	194	33	less	less	JJR
cord-010499-yefxrj30	194	34	.	.	.
cord-010499-yefxrj30	195	1	By	by	IN
cord-010499-yefxrj30	195	2	this	this	DT
cord-010499-yefxrj30	195	3	estimate	estimate	NN
cord-010499-yefxrj30	195	4	,	,	,
cord-010499-yefxrj30	195	5	therefore	therefore	RB
cord-010499-yefxrj30	195	6	,	,	,
cord-010499-yefxrj30	195	7	the	the	DT
cord-010499-yefxrj30	195	8	frequency	frequency	NN
cord-010499-yefxrj30	195	9	of	of	IN
cord-010499-yefxrj30	195	10	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	195	11	at	at	IN
cord-010499-yefxrj30	195	12	the	the	DT
cord-010499-yefxrj30	195	13	critical	critical	JJ
cord-010499-yefxrj30	195	14	leucine	leucine	NN
cord-010499-yefxrj30	195	15	codon	codon	NN
cord-010499-yefxrj30	195	16	was	be	VBD
cord-010499-yefxrj30	195	17	increased	increase	VBN
cord-010499-yefxrj30	195	18	about	about	IN
cord-010499-yefxrj30	195	19	sixfold	sixfold	RB
cord-010499-yefxrj30	195	20	at	at	IN
cord-010499-yefxrj30	195	21	3|igmr^	3|igmr^	CD
cord-010499-yefxrj30	195	22	of	of	IN
cord-010499-yefxrj30	195	23	the	the	DT
cord-010499-yefxrj30	195	24	leucine	leucine	NN
cord-010499-yefxrj30	195	25	analogue	analogue	NN
cord-010499-yefxrj30	195	26	,	,	,
cord-010499-yefxrj30	195	27	a	a	DT
cord-010499-yefxrj30	195	28	limitation	limitation	NN
cord-010499-yefxrj30	195	29	regimen	regimen	NN
cord-010499-yefxrj30	195	30	which	which	WDT
cord-010499-yefxrj30	195	31	reduced	reduce	VBD
cord-010499-yefxrj30	195	32	growth	growth	NN
cord-010499-yefxrj30	195	33	about	about	IN
cord-010499-yefxrj30	195	34	sevenfold	sevenfold	NNP
cord-010499-yefxrj30	195	35	.	.	.
cord-010499-yefxrj30	196	1	The	the	DT
cord-010499-yefxrj30	196	2	protein	protein	NN
cord-010499-yefxrj30	196	3	sequence	sequence	NN
cord-010499-yefxrj30	196	4	of	of	IN
cord-010499-yefxrj30	196	5	the	the	DT
cord-010499-yefxrj30	196	6	frameshifted	frameshifted	JJ
cord-010499-yefxrj30	196	7	material	material	NN
cord-010499-yefxrj30	196	8	(	(	-LRB-
cord-010499-yefxrj30	196	9	Fig	Fig	NNP
cord-010499-yefxrj30	196	10	.	.	.
cord-010499-yefxrj30	196	11	3	3	LS
cord-010499-yefxrj30	196	12	)	)	-RRB-
cord-010499-yefxrj30	196	13	demonstrates	demonstrate	VBZ
cord-010499-yefxrj30	196	14	that	that	IN
cord-010499-yefxrj30	196	15	the	the	DT
cord-010499-yefxrj30	196	16	ribosomes	ribosome	NNS
cord-010499-yefxrj30	196	17	read	read	VBD
cord-010499-yefxrj30	196	18	the	the	DT
cord-010499-yefxrj30	196	19	sequence	sequence	NN
cord-010499-yefxrj30	196	20	in	in	IN
cord-010499-yefxrj30	196	21	a	a	DT
cord-010499-yefxrj30	196	22	normal	normal	JJ
cord-010499-yefxrj30	196	23	fashion	fashion	NN
cord-010499-yefxrj30	196	24	for	for	IN
cord-010499-yefxrj30	196	25	the	the	DT
cord-010499-yefxrj30	196	26	first	first	JJ
cord-010499-yefxrj30	196	27	nine	nine	CD
cord-010499-yefxrj30	196	28	codons	codon	NNS
cord-010499-yefxrj30	196	29	,	,	,
cord-010499-yefxrj30	196	30	up	up	IN
cord-010499-yefxrj30	196	31	to	to	IN
cord-010499-yefxrj30	196	32	the	the	DT
cord-010499-yefxrj30	196	33	hungry	hungry	JJ
cord-010499-yefxrj30	196	34	codon	codon	NN
cord-010499-yefxrj30	196	35	calling	call	VBG
cord-010499-yefxrj30	196	36	for	for	IN
cord-010499-yefxrj30	196	37	leucine	leucine	NN
cord-010499-yefxrj30	196	38	at	at	IN
cord-010499-yefxrj30	196	39	position	position	NN
cord-010499-yefxrj30	196	40	10	10	CD
cord-010499-yefxrj30	196	41	.	.	.
cord-010499-yefxrj30	197	1	At	at	IN
cord-010499-yefxrj30	197	2	this	this	DT
cord-010499-yefxrj30	197	3	position	position	NN
cord-010499-yefxrj30	197	4	,	,	,
cord-010499-yefxrj30	197	5	the	the	DT
cord-010499-yefxrj30	197	6	predominant	predominant	JJ
cord-010499-yefxrj30	197	7	amino	amino	NN
cord-010499-yefxrj30	197	8	acid	acid	NN
cord-010499-yefxrj30	197	9	was	be	VBD
cord-010499-yefxrj30	197	10	F	F	NNP
cord-010499-yefxrj30	197	11	(	(	-LRB-
cord-010499-yefxrj30	197	12	phenylaianine	phenylaianine	NNP
cord-010499-yefxrj30	197	13	)	)	-RRB-
cord-010499-yefxrj30	197	14	rather	rather	RB
cord-010499-yefxrj30	197	15	than	than	IN
cord-010499-yefxrj30	197	16	L	L	NNP
cord-010499-yefxrj30	197	17	(	(	-LRB-
cord-010499-yefxrj30	197	18	leucine	leucine	NNP
cord-010499-yefxrj30	197	19	)	)	-RRB-
cord-010499-yefxrj30	197	20	,	,	,
cord-010499-yefxrj30	197	21	implying	imply	VBG
cord-010499-yefxrj30	197	22	that	that	IN
cord-010499-yefxrj30	197	23	the	the	DT
cord-010499-yefxrj30	197	24	ribosomes	ribosome	NNS
cord-010499-yefxrj30	197	25	slipped	slip	VBD
cord-010499-yefxrj30	197	26	leftward	leftward	RB
cord-010499-yefxrj30	197	27	to	to	TO
cord-010499-yefxrj30	197	28	decode	decode	VB
cord-010499-yefxrj30	197	29	the	the	DT
cord-010499-yefxrj30	197	30	TTT	TTT	NNP
cord-010499-yefxrj30	197	31	triplet	triplet	NN
cord-010499-yefxrj30	197	32	for	for	IN
cord-010499-yefxrj30	197	33	phenyialanine	phenyialanine	NNP
cord-010499-yefxrj30	197	34	,	,	,
cord-010499-yefxrj30	197	35	which	which	WDT
cord-010499-yefxrj30	197	36	overiaps	overiap	VBZ
cord-010499-yefxrj30	197	37	the	the	DT
cord-010499-yefxrj30	197	38	hungry	hungry	JJ
cord-010499-yefxrj30	197	39	codon	codon	NN
cord-010499-yefxrj30	197	40	from	from	IN
cord-010499-yefxrj30	197	41	the	the	DT
cord-010499-yefxrj30	197	42	left	left	NN
cord-010499-yefxrj30	197	43	.	.	.
cord-010499-yefxrj30	198	1	This	this	DT
cord-010499-yefxrj30	198	2	overlapping	overlapping	JJ
cord-010499-yefxrj30	198	3	mode	mode	NN
cord-010499-yefxrj30	198	4	of	of	IN
cord-010499-yefxrj30	198	5	reading	reading	NN
cord-010499-yefxrj30	198	6	is	be	VBZ
cord-010499-yefxrj30	198	7	entirely	entirely	RB
cord-010499-yefxrj30	198	8	analogous	analogous	JJ
cord-010499-yefxrj30	198	9	to	to	IN
cord-010499-yefxrj30	198	10	the	the	DT
cord-010499-yefxrj30	198	11	case	case	NN
cord-010499-yefxrj30	198	12	of	of	IN
cord-010499-yefxrj30	198	13	leftward	leftward	NNP
cord-010499-yefxrj30	198	14	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	198	15	at	at	IN
cord-010499-yefxrj30	198	16	a	a	DT
cord-010499-yefxrj30	198	17	different	different	JJ
cord-010499-yefxrj30	198	18	hungry	hungry	JJ
cord-010499-yefxrj30	198	19	codon	codon	NN
cord-010499-yefxrj30	198	20	we	-PRON-	PRP
cord-010499-yefxrj30	198	21	have	have	VBP
cord-010499-yefxrj30	198	22	described	describe	VBN
cord-010499-yefxrj30	198	23	earlier	early	RBR
cord-010499-yefxrj30	198	24	.	.	.
cord-010499-yefxrj30	199	1	However	however	RB
cord-010499-yefxrj30	199	2	,	,	,
cord-010499-yefxrj30	199	3	there	there	EX
cord-010499-yefxrj30	199	4	is	be	VBZ
cord-010499-yefxrj30	199	5	also	also	RB
cord-010499-yefxrj30	199	6	a	a	DT
cord-010499-yefxrj30	199	7	significant	significant	JJ
cord-010499-yefxrj30	199	8	secondary	secondary	JJ
cord-010499-yefxrj30	199	9	peak	peak	NN
cord-010499-yefxrj30	199	10	of	of	IN
cord-010499-yefxrj30	199	11	leucine	leucine	NN
cord-010499-yefxrj30	199	12	at	at	IN
cord-010499-yefxrj30	199	13	position	position	NN
cord-010499-yefxrj30	199	14	10	10	CD
cord-010499-yefxrj30	199	15	,	,	,
cord-010499-yefxrj30	199	16	amounting	amount	VBG
cord-010499-yefxrj30	199	17	to	to	IN
cord-010499-yefxrj30	199	18	one	one	CD
cord-010499-yefxrj30	199	19	third	third	NN
cord-010499-yefxrj30	199	20	of	of	IN
cord-010499-yefxrj30	199	21	the	the	DT
cord-010499-yefxrj30	199	22	total	total	JJ
cord-010499-yefxrj30	199	23	signal	signal	NN
cord-010499-yefxrj30	199	24	(	(	-LRB-
cord-010499-yefxrj30	199	25	Fig	Fig	NNP
cord-010499-yefxrj30	199	26	.	.	.
cord-010499-yefxrj30	199	27	3	3	CD
cord-010499-yefxrj30	199	28	)	)	-RRB-
cord-010499-yefxrj30	199	29	.	.	.
cord-010499-yefxrj30	200	1	This	this	DT
cord-010499-yefxrj30	200	2	is	be	VBZ
cord-010499-yefxrj30	200	3	the	the	DT
cord-010499-yefxrj30	200	4	amino	amino	NN
cord-010499-yefxrj30	200	5	acid	acid	NN
cord-010499-yefxrj30	200	6	encoded	encode	VBN
cord-010499-yefxrj30	200	7	in	in	IN
cord-010499-yefxrj30	200	8	(	(	-LRB-
cord-010499-yefxrj30	200	9	he	-PRON-	PRP
cord-010499-yefxrj30	200	10	initial	initial	JJ
cord-010499-yefxrj30	200	11	or	or	CC
cord-010499-yefxrj30	200	12	(	(	-LRB-
cord-010499-yefxrj30	200	13	0	0	NFP
cord-010499-yefxrj30	200	14	)	)	-RRB-
cord-010499-yefxrj30	200	15	reading	reading	NN
cord-010499-yefxrj30	200	16	frame	frame	NN
cord-010499-yefxrj30	200	17	.	.	.
cord-010499-yefxrj30	201	1	The	the	DT
cord-010499-yefxrj30	201	2	presence	presence	NN
cord-010499-yefxrj30	201	3	of	of	IN
cord-010499-yefxrj30	201	4	leucine	leucine	NN
cord-010499-yefxrj30	201	5	here	here	RB
cord-010499-yefxrj30	201	6	strongly	strongly	RB
cord-010499-yefxrj30	201	7	suggests	suggest	VBZ
cord-010499-yefxrj30	201	8	that	that	IN
cord-010499-yefxrj30	201	9	a	a	DT
cord-010499-yefxrj30	201	10	minority	minority	NN
cord-010499-yefxrj30	201	11	of	of	IN
cord-010499-yefxrj30	201	12	ribosomes	ribosome	NNS
cord-010499-yefxrj30	201	13	bound	bind	VBN
cord-010499-yefxrj30	201	14	leucyl	leucyl	NNP
cord-010499-yefxrj30	201	15	-	-	HYPH
cord-010499-yefxrj30	201	16	tRNA	tRNA	NNP
cord-010499-yefxrj30	201	17	and	and	CC
cord-010499-yefxrj30	201	18	then	then	RB
cord-010499-yefxrj30	201	19	slipped	slip	VBD
cord-010499-yefxrj30	201	20	leftward	leftward	RB
cord-010499-yefxrj30	201	21	,	,	,
cord-010499-yefxrj30	201	22	just	just	RB
cord-010499-yefxrj30	201	23	as	as	IN
cord-010499-yefxrj30	201	24	a	a	DT
cord-010499-yefxrj30	201	25	majority	majority	NN
cord-010499-yefxrj30	201	26	of	of	IN
cord-010499-yefxrj30	201	27	ribosomes	ribosome	NNS
cord-010499-yefxrj30	201	28	did	do	VBD
cord-010499-yefxrj30	201	29	under	under	IN
cord-010499-yefxrj30	201	30	conditions	condition	NNS
cord-010499-yefxrj30	201	31	of	of	IN
cord-010499-yefxrj30	201	32	(	(	-LRB-
cord-010499-yefxrj30	201	33	eucine	eucine	JJ
cord-010499-yefxrj30	201	34	sufficiency	sufficiency	NN
cord-010499-yefxrj30	201	35	.	.	.
cord-010499-yefxrj30	202	1	Thus	thus	RB
cord-010499-yefxrj30	202	2	,	,	,
cord-010499-yefxrj30	202	3	the	the	DT
cord-010499-yefxrj30	202	4	HIV	HIV	NNP
cord-010499-yefxrj30	202	5	sequence	sequence	NN
cord-010499-yefxrj30	202	6	is	be	VBZ
cord-010499-yefxrj30	202	7	subject	subject	JJ
cord-010499-yefxrj30	202	8	to	to	IN
cord-010499-yefxrj30	202	9	starvationpromoted	starvationpromoted	JJ
cord-010499-yefxrj30	202	10	frameshifting	frameshifting	NN
cord-010499-yefxrj30	202	11	on	on	IN
cord-010499-yefxrj30	202	12	E.	E.	NNP
cord-010499-yefxrj30	202	13	coli	coli	NNS
cord-010499-yefxrj30	202	14	ribosomes	ribosome	NNS
cord-010499-yefxrj30	202	15	,	,	,
cord-010499-yefxrj30	202	16	and	and	CC
cord-010499-yefxrj30	202	17	by	by	IN
cord-010499-yefxrj30	202	18	two	two	CD
cord-010499-yefxrj30	202	19	seemingly	seemingly	RB
cord-010499-yefxrj30	202	20	different	different	JJ
cord-010499-yefxrj30	202	21	mechanisms	mechanism	NNS
cord-010499-yefxrj30	202	22	.	.	.
cord-010499-yefxrj30	203	1	One	one	CD
cord-010499-yefxrj30	203	2	is	be	VBZ
cord-010499-yefxrj30	203	3	overlapping	overlap	VBG
cord-010499-yefxrj30	203	4	reading	reading	NN
cord-010499-yefxrj30	203	5	at	at	IN
cord-010499-yefxrj30	203	6	the	the	DT
cord-010499-yefxrj30	203	7	hungry	hungry	JJ
cord-010499-yefxrj30	203	8	codon	codon	NN
cord-010499-yefxrj30	203	9	.	.	.
cord-010499-yefxrj30	204	1	like	like	IN
cord-010499-yefxrj30	204	2	the	the	DT
cord-010499-yefxrj30	204	3	cases	case	NNS
cord-010499-yefxrj30	204	4	we	-PRON-	PRP
cord-010499-yefxrj30	204	5	have	have	VBP
cord-010499-yefxrj30	204	6	analysed	analyse	VBN
cord-010499-yefxrj30	204	7	elsewhere	elsewhere	RB
cord-010499-yefxrj30	204	8	(	(	-LRB-
cord-010499-yefxrj30	204	9	Weiss	Weiss	NNP
cord-010499-yefxrj30	204	10	and	and	CC
cord-010499-yefxrj30	204	11	Gallant	Gallant	NNP
cord-010499-yefxrj30	204	12	,	,	,
cord-010499-yefxrj30	204	13	1986	1986	CD
cord-010499-yefxrj30	204	14	;	;	:
cord-010499-yefxrj30	204	15	Gailant	Gailant	NNP
cord-010499-yefxrj30	204	16	and	and	CC
cord-010499-yefxrj30	204	17	Linsdiey	Linsdiey	NNP
cord-010499-yefxrj30	204	18	,	,	,
cord-010499-yefxrj30	204	19	1992	1992	CD
cord-010499-yefxrj30	204	20	)	)	-RRB-
cord-010499-yefxrj30	204	21	.	.	.
cord-010499-yefxrj30	205	1	The	the	DT
cord-010499-yefxrj30	205	2	second	second	JJ
cord-010499-yefxrj30	205	3	is	be	VBZ
cord-010499-yefxrj30	205	4	zero	zero	CD
cord-010499-yefxrj30	205	5	-	-	HYPH
cord-010499-yefxrj30	205	6	frame	frame	NN
cord-010499-yefxrj30	205	7	reading	reading	NN
cord-010499-yefxrj30	205	8	and	and	CC
cord-010499-yefxrj30	205	9	subsequent	subsequent	JJ
cord-010499-yefxrj30	205	10	siippage	siippage	NN
cord-010499-yefxrj30	205	11	-	-	HYPH
cord-010499-yefxrj30	205	12	inserting	insert	VBG
cord-010499-yefxrj30	205	13	leucine	leucine	NN
cord-010499-yefxrj30	205	14	at	at	IN
cord-010499-yefxrj30	205	15	position	position	NN
cord-010499-yefxrj30	205	16	10	10	CD
cord-010499-yefxrj30	205	17	in	in	IN
cord-010499-yefxrj30	205	18	this	this	DT
cord-010499-yefxrj30	205	19	caseanaiagous	caseanaiagous	JJ
cord-010499-yefxrj30	205	20	to	to	IN
cord-010499-yefxrj30	205	21	other	other	JJ
cord-010499-yefxrj30	205	22	studies	study	NNS
cord-010499-yefxrj30	205	23	of	of	IN
cord-010499-yefxrj30	205	24	the	the	DT
cord-010499-yefxrj30	205	25	translation	translation	NN
cord-010499-yefxrj30	205	26	of	of	IN
cord-010499-yefxrj30	205	27	HIV	HIV	NNP
cord-010499-yefxrj30	205	28	(	(	-LRB-
cord-010499-yefxrj30	205	29	Jacks	Jacks	NNP
cord-010499-yefxrj30	205	30	etai	etai	NNP
cord-010499-yefxrj30	205	31	,	,	,
cord-010499-yefxrj30	205	32	1988b	1988b	CD
cord-010499-yefxrj30	205	33	;	;	:
cord-010499-yefxrj30	205	34	Weiss	Weiss	NNP
cord-010499-yefxrj30	205	35	etal	etal	NNP
cord-010499-yefxrj30	205	36	..	..	NFP
cord-010499-yefxrj30	205	37	1989	1989	CD
cord-010499-yefxrj30	205	38	)	)	-RRB-
cord-010499-yefxrj30	205	39	or	or	CC
cord-010499-yefxrj30	205	40	rous	rous	JJ
cord-010499-yefxrj30	205	41	sarcoma	sarcoma	NN
cord-010499-yefxrj30	205	42	virus	virus	NN
cord-010499-yefxrj30	205	43	(	(	-LRB-
cord-010499-yefxrj30	205	44	RSV	RSV	NNP
cord-010499-yefxrj30	205	45	)	)	-RRB-
cord-010499-yefxrj30	206	1	(	(	-LRB-
cord-010499-yefxrj30	206	2	Jacks	Jacks	NNP
cord-010499-yefxrj30	206	3	etai	etai	NNP
cord-010499-yefxrj30	206	4	.	.	.
cord-010499-yefxrj30	207	1	1988a	1988a	LS
cord-010499-yefxrj30	207	2	)	)	-RRB-
cord-010499-yefxrj30	207	3	in	in	IN
cord-010499-yefxrj30	207	4	heteroiogous	heteroiogous	NNP
cord-010499-yefxrj30	207	5	systems	system	NNS
cord-010499-yefxrj30	207	6	.	.	.
cord-010499-yefxrj30	208	1	In	in	IN
cord-010499-yefxrj30	208	2	fact	fact	NN
cord-010499-yefxrj30	208	3	,	,	,
cord-010499-yefxrj30	208	4	a	a	DT
cord-010499-yefxrj30	208	5	close	close	JJ
cord-010499-yefxrj30	208	6	reading	reading	NN
cord-010499-yefxrj30	208	7	of	of	IN
cord-010499-yefxrj30	208	8	the	the	DT
cord-010499-yefxrj30	208	9	data	datum	NNS
cord-010499-yefxrj30	208	10	of	of	IN
cord-010499-yefxrj30	208	11	Jacks	Jacks	NNP
cord-010499-yefxrj30	208	12	e	e	NNP
cord-010499-yefxrj30	208	13	/	/	SYM
cord-010499-yefxrj30	208	14	a/.	a/.	NNP
cord-010499-yefxrj30	208	15	(	(	-LRB-
cord-010499-yefxrj30	208	16	1988b	1988b	CD
cord-010499-yefxrj30	208	17	)	)	-RRB-
cord-010499-yefxrj30	208	18	reveais	reveais	NNP
cord-010499-yefxrj30	208	19	that	that	WDT
cord-010499-yefxrj30	208	20	the	the	DT
cord-010499-yefxrj30	208	21	HiV	HiV	NNP
cord-010499-yefxrj30	208	22	sequence	sequence	NN
cord-010499-yefxrj30	208	23	also	also	RB
cord-010499-yefxrj30	208	24	displayed	display	VBD
cord-010499-yefxrj30	208	25	both	both	DT
cord-010499-yefxrj30	208	26	modes	mode	NNS
cord-010499-yefxrj30	208	27	of	of	IN
cord-010499-yefxrj30	208	28	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	208	29	in	in	IN
cord-010499-yefxrj30	208	30	the	the	DT
cord-010499-yefxrj30	208	31	eukaryotic	eukaryotic	JJ
cord-010499-yefxrj30	208	32	cell	cell	NN
cord-010499-yefxrj30	208	33	-	-	HYPH
cord-010499-yefxrj30	208	34	free	free	JJ
cord-010499-yefxrj30	208	35	translation	translation	NN
cord-010499-yefxrj30	208	36	system	system	NN
cord-010499-yefxrj30	208	37	they	-PRON-	PRP
cord-010499-yefxrj30	208	38	analysed	analyse	VBD
cord-010499-yefxrj30	208	39	.	.	.
cord-010499-yefxrj30	209	1	The	the	DT
cord-010499-yefxrj30	209	2	predominant	predominant	JJ
cord-010499-yefxrj30	209	3	amino	amino	NN
cord-010499-yefxrj30	209	4	acid	acid	NN
cord-010499-yefxrj30	209	5	at	at	IN
cord-010499-yefxrj30	209	6	the	the	DT
cord-010499-yefxrj30	209	7	frameshift	frameshift	NN
cord-010499-yefxrj30	209	8	site	site	NN
cord-010499-yefxrj30	210	1	In	in	IN
cord-010499-yefxrj30	210	2	their	-PRON-	PRP$
cord-010499-yefxrj30	210	3	study	study	NN
cord-010499-yefxrj30	210	4	was	be	VBD
cord-010499-yefxrj30	210	5	leucine	leucine	JJ
cord-010499-yefxrj30	210	6	.	.	.
cord-010499-yefxrj30	211	1	but	but	CC
cord-010499-yefxrj30	211	2	there	there	EX
cord-010499-yefxrj30	211	3	was	be	VBD
cord-010499-yefxrj30	211	4	aiso	aiso	VBN
cord-010499-yefxrj30	211	5	about	about	RB
cord-010499-yefxrj30	211	6	20	20	CD
cord-010499-yefxrj30	211	7	-	-	SYM
cord-010499-yefxrj30	211	8	25	25	CD
cord-010499-yefxrj30	211	9	%	%	NN
cord-010499-yefxrj30	211	10	phenyialanine	phenyialanine	NN
cord-010499-yefxrj30	211	11	(	(	-LRB-
cord-010499-yefxrj30	211	12	see	see	VB
cord-010499-yefxrj30	211	13	Fig	Fig	NNP
cord-010499-yefxrj30	211	14	.	.	.
cord-010499-yefxrj30	212	1	2	2	CD
cord-010499-yefxrj30	212	2	of	of	IN
cord-010499-yefxrj30	212	3	Jacks	Jacks	NNP
cord-010499-yefxrj30	212	4	et	et	NNP
cord-010499-yefxrj30	212	5	ai	ai	NN
cord-010499-yefxrj30	212	6	,	,	,
cord-010499-yefxrj30	212	7	198Bb	198bb	CD
cord-010499-yefxrj30	212	8	)	)	-RRB-
cord-010499-yefxrj30	212	9	.	.	.
cord-010499-yefxrj30	213	1	indicative	indicative	JJ
cord-010499-yefxrj30	213	2	of	of	IN
cord-010499-yefxrj30	213	3	overiapping	overiappe	VBG
cord-010499-yefxrj30	213	4	reading	reading	NN
cord-010499-yefxrj30	213	5	.	.	.
cord-010499-yefxrj30	214	1	Our	-PRON-	PRP$
cord-010499-yefxrj30	214	2	results	result	NNS
cord-010499-yefxrj30	214	3	in	in	IN
cord-010499-yefxrj30	214	4	unstarved	unstarved	JJ
cord-010499-yefxrj30	214	5	cells	cell	NNS
cord-010499-yefxrj30	214	6	(	(	-LRB-
cord-010499-yefxrj30	214	7	our	-PRON-	PRP$
cord-010499-yefxrj30	214	8	Fig	Fig	NNP
cord-010499-yefxrj30	214	9	.	.	NNP
cord-010499-yefxrj30	214	10	2	2	LS
cord-010499-yefxrj30	214	11	)	)	-RRB-
cord-010499-yefxrj30	214	12	indicate	indicate	VBP
cord-010499-yefxrj30	214	13	about	about	IN
cord-010499-yefxrj30	214	14	30	30	CD
cord-010499-yefxrj30	214	15	%	%	NN
cord-010499-yefxrj30	214	16	phenyialanine	phenyialanine	NN
cord-010499-yefxrj30	214	17	.	.	.
cord-010499-yefxrj30	215	1	These	these	DT
cord-010499-yefxrj30	215	2	two	two	CD
cord-010499-yefxrj30	215	3	modes	mode	NNS
cord-010499-yefxrj30	215	4	of	of	IN
cord-010499-yefxrj30	215	5	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	215	6	share	share	NN
cord-010499-yefxrj30	215	7	fundamentai	fundamentai	NNP
cord-010499-yefxrj30	215	8	similarities	similarity	NNS
cord-010499-yefxrj30	215	9	,	,	,
cord-010499-yefxrj30	215	10	most	most	RBS
cord-010499-yefxrj30	215	11	strikingly	strikingly	RB
cord-010499-yefxrj30	215	12	in	in	IN
cord-010499-yefxrj30	215	13	regard	regard	NN
cord-010499-yefxrj30	215	14	to	to	IN
cord-010499-yefxrj30	215	15	their	-PRON-	PRP$
cord-010499-yefxrj30	215	16	sequence	sequence	NN
cord-010499-yefxrj30	215	17	requirements	requirement	NNS
cord-010499-yefxrj30	215	18	in	in	IN
cord-010499-yefxrj30	215	19	the	the	DT
cord-010499-yefxrj30	215	20	four	four	CD
cord-010499-yefxrj30	215	21	positions	position	NNS
cord-010499-yefxrj30	215	22	to	to	IN
cord-010499-yefxrj30	215	23	the	the	DT
cord-010499-yefxrj30	215	24	left	left	NN
cord-010499-yefxrj30	215	25	of	of	IN
cord-010499-yefxrj30	215	26	the	the	DT
cord-010499-yefxrj30	215	27	frameshift	frameshift	NN
cord-010499-yefxrj30	215	28	site	site	NN
cord-010499-yefxrj30	215	29	.	.	.
cord-010499-yefxrj30	216	1	In	in	IN
cord-010499-yefxrj30	216	2	the	the	DT
cord-010499-yefxrj30	216	3	case	case	NN
cord-010499-yefxrj30	216	4	of	of	IN
cord-010499-yefxrj30	216	5	the	the	DT
cord-010499-yefxrj30	216	6	mechanism	mechanism	NN
cord-010499-yefxrj30	216	7	of	of	IN
cord-010499-yefxrj30	216	8	(	(	-LRB-
cord-010499-yefxrj30	216	9	0	0	NFP
cord-010499-yefxrj30	216	10	)	)	-RRB-
cord-010499-yefxrj30	216	11	frame	frame	NN
cord-010499-yefxrj30	216	12	tRNA	trna	NN
cord-010499-yefxrj30	216	13	binding	binding	NN
cord-010499-yefxrj30	216	14	followed	follow	VBN
cord-010499-yefxrj30	216	15	by	by	IN
cord-010499-yefxrj30	216	16	slippage	slippage	NN
cord-010499-yefxrj30	216	17	,	,	,
cord-010499-yefxrj30	216	18	mutation	mutation	NN
cord-010499-yefxrj30	216	19	studies	study	NNS
cord-010499-yefxrj30	216	20	in	in	IN
cord-010499-yefxrj30	216	21	this	this	DT
cord-010499-yefxrj30	216	22	region	region	NN
cord-010499-yefxrj30	216	23	strongiy	strongiy	NN
cord-010499-yefxrj30	216	24	suggest	suggest	VBP
cord-010499-yefxrj30	216	25	that	that	IN
cord-010499-yefxrj30	216	26	the	the	DT
cord-010499-yefxrj30	216	27	frameshift	frameshift	NN
cord-010499-yefxrj30	216	28	is	be	VBZ
cord-010499-yefxrj30	216	29	facilitated	facilitate	VBN
cord-010499-yefxrj30	216	30	by	by	IN
cord-010499-yefxrj30	216	31	a	a	DT
cord-010499-yefxrj30	216	32	leftward	leftward	JJ
cord-010499-yefxrj30	216	33	slip	slip	NN
cord-010499-yefxrj30	216	34	of	of	IN
cord-010499-yefxrj30	216	35	peptidyl	peptidyl	NNP
cord-010499-yefxrj30	216	36	-	-	HYPH
cord-010499-yefxrj30	216	37	tRNA	trna	NN
cord-010499-yefxrj30	216	38	in	in	IN
cord-010499-yefxrj30	216	39	the	the	DT
cord-010499-yefxrj30	216	40	P	p	NN
cord-010499-yefxrj30	216	41	-	-	HYPH
cord-010499-yefxrj30	216	42	site	site	NN
cord-010499-yefxrj30	217	1	(	(	-LRB-
cord-010499-yefxrj30	217	2	Jacks	Jacks	NNP
cord-010499-yefxrj30	217	3	et	et	NNP
cord-010499-yefxrj30	217	4	al	al	NNP
cord-010499-yefxrj30	217	5	..	..	NNP
cord-010499-yefxrj30	217	6	1988a.b	1988a.b	CD
cord-010499-yefxrj30	217	7	;	;	:
cord-010499-yefxrj30	217	8	Wilson	Wilson	NNP
cord-010499-yefxrj30	217	9	ef	ef	NNP
cord-010499-yefxrj30	217	10	al	al	NNP
cord-010499-yefxrj30	217	11	.	.	.
cord-010499-yefxrj30	218	1	,	,	,
cord-010499-yefxrj30	218	2	1988	1988	CD
cord-010499-yefxrj30	218	3	;	;	:
cord-010499-yefxrj30	218	4	Weiss	Weiss	NNP
cord-010499-yefxrj30	218	5	et	et	NNP
cord-010499-yefxrj30	218	6	ai	ai	NNP
cord-010499-yefxrj30	218	7	,	,	,
cord-010499-yefxrj30	218	8	1989	1989	CD
cord-010499-yefxrj30	218	9	)	)	-RRB-
cord-010499-yefxrj30	218	10	.	.	.
cord-010499-yefxrj30	219	1	In	in	IN
cord-010499-yefxrj30	219	2	the	the	DT
cord-010499-yefxrj30	219	3	case	case	NN
cord-010499-yefxrj30	219	4	of	of	IN
cord-010499-yefxrj30	219	5	tiie	tiie	NN
cord-010499-yefxrj30	219	6	overlapping	overlapping	JJ
cord-010499-yefxrj30	219	7	reading	reading	NN
cord-010499-yefxrj30	219	8	mechanism	mechanism	NN
cord-010499-yefxrj30	219	9	,	,	,
cord-010499-yefxrj30	219	10	our	-PRON-	PRP$
cord-010499-yefxrj30	219	11	mutation	mutation	NN
cord-010499-yefxrj30	219	12	studies	study	NNS
cord-010499-yefxrj30	219	13	suggest	suggest	VBP
cord-010499-yefxrj30	219	14	a	a	DT
cord-010499-yefxrj30	219	15	similar	similar	JJ
cord-010499-yefxrj30	219	16	involvement	involvement	NN
cord-010499-yefxrj30	219	17	of	of	IN
cord-010499-yefxrj30	219	18	a	a	DT
cord-010499-yefxrj30	219	19	peptidyl	peptidyl	JJ
cord-010499-yefxrj30	219	20	shiiX	shiiX	NNP
cord-010499-yefxrj30	219	21	{	{	-LRB-
cord-010499-yefxrj30	219	22	KO\OT	ko\ot	FW
cord-010499-yefxrj30	219	23	et	et	FW
cord-010499-yefxrj30	219	24	ai	ai	NN
cord-010499-yefxrj30	219	25	.	.	.
cord-010499-yefxrj30	219	26	1993	1993	CD
cord-010499-yefxrj30	219	27	)	)	-RRB-
cord-010499-yefxrj30	219	28	.	.	.
cord-010499-yefxrj30	220	1	Thus	thus	RB
cord-010499-yefxrj30	220	2	,	,	,
cord-010499-yefxrj30	220	3	in	in	IN
cord-010499-yefxrj30	220	4	both	both	DT
cord-010499-yefxrj30	220	5	mechanisms	mechanism	NNS
cord-010499-yefxrj30	220	6	the	the	DT
cord-010499-yefxrj30	220	7	leftward	leftward	JJ
cord-010499-yefxrj30	220	8	slippage	slippage	NN
cord-010499-yefxrj30	220	9	at	at	IN
cord-010499-yefxrj30	220	10	the	the	DT
cord-010499-yefxrj30	220	11	ribosome	ribosome	NN
cord-010499-yefxrj30	220	12	's	's	POS
cord-010499-yefxrj30	220	13	A	A	NNP
cord-010499-yefxrj30	220	14	-	-	HYPH
cord-010499-yefxrj30	220	15	site	site	NN
cord-010499-yefxrj30	220	16	is	be	VBZ
cord-010499-yefxrj30	220	17	facilitated	facilitate	VBN
cord-010499-yefxrj30	220	18	if	if	IN
cord-010499-yefxrj30	220	19	the	the	DT
cord-010499-yefxrj30	220	20	adjacent	adjacent	JJ
cord-010499-yefxrj30	220	21	peptidyl	peptidyl	NNP
cord-010499-yefxrj30	220	22	-	-	HYPH
cord-010499-yefxrj30	220	23	tRNA	tRNA	NNP
cord-010499-yefxrj30	220	24	finds	find	VBZ
cord-010499-yefxrj30	220	25	complementary	complementary	JJ
cord-010499-yefxrj30	220	26	pairing	pairing	NN
cord-010499-yefxrj30	220	27	with	with	IN
cord-010499-yefxrj30	220	28	a	a	DT
cord-010499-yefxrj30	220	29	left	left	RB
cord-010499-yefxrj30	220	30	-	-	HYPH
cord-010499-yefxrj30	220	31	shifted	shift	VBN
cord-010499-yefxrj30	220	32	triplet	triplet	NN
cord-010499-yefxrj30	220	33	at	at	IN
cord-010499-yefxrj30	220	34	the	the	DT
cord-010499-yefxrj30	220	35	P	p	NN
cord-010499-yefxrj30	220	36	-	-	HYPH
cord-010499-yefxrj30	220	37	site	site	NN
cord-010499-yefxrj30	220	38	.	.	.
cord-010499-yefxrj30	221	1	The	the	DT
cord-010499-yefxrj30	221	2	distinction	distinction	NN
cord-010499-yefxrj30	221	3	between	between	IN
cord-010499-yefxrj30	221	4	the	the	DT
cord-010499-yefxrj30	221	5	two	two	CD
cord-010499-yefxrj30	221	6	meciianisms	meciianism	NNS
cord-010499-yefxrj30	221	7	seems	seem	VBZ
cord-010499-yefxrj30	221	8	,	,	,
cord-010499-yefxrj30	221	9	at	at	IN
cord-010499-yefxrj30	221	10	first	first	RB
cord-010499-yefxrj30	221	11	thought	thought	NN
cord-010499-yefxrj30	221	12	,	,	,
cord-010499-yefxrj30	221	13	to	to	TO
cord-010499-yefxrj30	221	14	reside	reside	VB
cord-010499-yefxrj30	221	15	in	in	IN
cord-010499-yefxrj30	221	16	the	the	DT
cord-010499-yefxrj30	221	17	order	order	NN
cord-010499-yefxrj30	221	18	in	in	IN
cord-010499-yefxrj30	221	19	which	which	WDT
cord-010499-yefxrj30	221	20	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	221	21	-	-	HYPH
cord-010499-yefxrj30	221	22	tRNA	trna	NN
cord-010499-yefxrj30	221	23	binding	binding	NN
cord-010499-yefxrj30	221	24	and	and	CC
cord-010499-yefxrj30	221	25	slippage	slippage	NN
cord-010499-yefxrj30	221	26	of	of	IN
cord-010499-yefxrj30	221	27	the	the	DT
cord-010499-yefxrj30	221	28	message	message	NN
cord-010499-yefxrj30	221	29	occur	occur	VBP
cord-010499-yefxrj30	221	30	.	.	.
cord-010499-yefxrj30	222	1	However	however	RB
cord-010499-yefxrj30	222	2	,	,	,
cord-010499-yefxrj30	222	3	this	this	DT
cord-010499-yefxrj30	222	4	distinction	distinction	NN
cord-010499-yefxrj30	222	5	may	may	MD
cord-010499-yefxrj30	222	6	be	be	VB
cord-010499-yefxrj30	222	7	more	more	RBR
cord-010499-yefxrj30	222	8	apparent	apparent	JJ
cord-010499-yefxrj30	222	9	than	than	IN
cord-010499-yefxrj30	222	10	real	real	JJ
cord-010499-yefxrj30	222	11	.	.	.
cord-010499-yefxrj30	223	1	It	-PRON-	PRP
cord-010499-yefxrj30	223	2	could	could	MD
cord-010499-yefxrj30	223	3	be	be	VB
cord-010499-yefxrj30	223	4	that	that	IN
cord-010499-yefxrj30	223	5	the	the	DT
cord-010499-yefxrj30	223	6	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	223	7	-	-	HYPH
cord-010499-yefxrj30	223	8	tRNA	tRNA	NNP
cord-010499-yefxrj30	223	9	that	that	WDT
cord-010499-yefxrj30	223	10	reads	read	VBZ
cord-010499-yefxrj30	223	11	tiie	tiie	NN
cord-010499-yefxrj30	223	12	overlapping	overlap	VBG
cord-010499-yefxrj30	223	13	codon	codon	NN
cord-010499-yefxrj30	223	14	first	first	RB
cord-010499-yefxrj30	223	15	enters	enter	VBZ
cord-010499-yefxrj30	223	16	the	the	DT
cord-010499-yefxrj30	223	17	A	A	NNP
cord-010499-yefxrj30	223	18	-	-	HYPH
cord-010499-yefxrj30	223	19	site	site	NN
cord-010499-yefxrj30	223	20	in	in	IN
cord-010499-yefxrj30	223	21	the	the	DT
cord-010499-yefxrj30	223	22	(	(	-LRB-
cord-010499-yefxrj30	223	23	0	0	NFP
cord-010499-yefxrj30	223	24	)	)	-RRB-
cord-010499-yefxrj30	223	25	frame	frame	NN
cord-010499-yefxrj30	223	26	by	by	IN
cord-010499-yefxrj30	223	27	way	way	NN
cord-010499-yefxrj30	223	28	of	of	IN
cord-010499-yefxrj30	223	29	a	a	DT
cord-010499-yefxrj30	223	30	mismatch	mismatch	NN
cord-010499-yefxrj30	223	31	.	.	.
cord-010499-yefxrj30	224	1	In	in	IN
cord-010499-yefxrj30	224	2	the	the	DT
cord-010499-yefxrj30	224	3	present	present	JJ
cord-010499-yefxrj30	224	4	case	case	NN
cord-010499-yefxrj30	224	5	,	,	,
cord-010499-yefxrj30	224	6	this	this	DT
cord-010499-yefxrj30	224	7	would	would	MD
cord-010499-yefxrj30	224	8	mean	mean	VB
cord-010499-yefxrj30	224	9	phe	phe	NNP
cord-010499-yefxrj30	224	10	-	-	HYPH
cord-010499-yefxrj30	224	11	tRNA	tRNA	NNP
cord-010499-yefxrj30	224	12	pairing	pair	VBG
cord-010499-yefxrj30	224	13	initialiy	initialiy	NNP
cord-010499-yefxrj30	224	14	with	with	IN
cord-010499-yefxrj30	224	15	the	the	DT
cord-010499-yefxrj30	224	16	UUA	UUA	NNP
cord-010499-yefxrj30	224	17	leucine	leucine	NN
cord-010499-yefxrj30	224	18	codon	codon	NN
cord-010499-yefxrj30	224	19	,	,	,
cord-010499-yefxrj30	224	20	an	an	DT
cord-010499-yefxrj30	224	21	interaction	interaction	NN
cord-010499-yefxrj30	224	22	which	which	WDT
cord-010499-yefxrj30	224	23	demands	demand	VBZ
cord-010499-yefxrj30	224	24	one	one	CD
cord-010499-yefxrj30	224	25	mismatch	mismatch	NN
cord-010499-yefxrj30	224	26	in	in	IN
cord-010499-yefxrj30	224	27	the	the	DT
cord-010499-yefxrj30	224	28	third	third	JJ
cord-010499-yefxrj30	224	29	position	position	NN
cord-010499-yefxrj30	224	30	.	.	.
cord-010499-yefxrj30	225	1	This	this	DT
cord-010499-yefxrj30	225	2	non	non	JJ
cord-010499-yefxrj30	225	3	-	-	JJ
cord-010499-yefxrj30	225	4	cognate	cognate	JJ
cord-010499-yefxrj30	225	5	interaction	interaction	NN
cord-010499-yefxrj30	225	6	would	would	MD
cord-010499-yefxrj30	225	7	of	of	IN
cord-010499-yefxrj30	225	8	course	course	RB
cord-010499-yefxrj30	225	9	be	be	VB
cord-010499-yefxrj30	225	10	favoured	favour	VBN
cord-010499-yefxrj30	225	11	by	by	IN
cord-010499-yefxrj30	225	12	a	a	DT
cord-010499-yefxrj30	225	13	shortage	shortage	NN
cord-010499-yefxrj30	225	14	of	of	IN
cord-010499-yefxrj30	225	15	leucyl	leucyl	NNP
cord-010499-yefxrj30	225	16	-	-	HYPH
cord-010499-yefxrj30	225	17	tRNA	tRNA	NNP
cord-010499-yefxrj30	225	18	,	,	,
cord-010499-yefxrj30	225	19	particularly	particularly	RB
cord-010499-yefxrj30	225	20	in	in	IN
cord-010499-yefxrj30	225	21	our	-PRON-	PRP$
cord-010499-yefxrj30	225	22	relA~	rela~	NN
cord-010499-yefxrj30	225	23	host	host	NN
cord-010499-yefxrj30	225	24	cells	cell	NNS
cord-010499-yefxrj30	225	25	which	which	WDT
cord-010499-yefxrj30	225	26	suffer	suffer	VBP
cord-010499-yefxrj30	225	27	increased	increase	VBN
cord-010499-yefxrj30	225	28	recognition	recognition	NN
cord-010499-yefxrj30	225	29	errors	error	NNS
cord-010499-yefxrj30	225	30	at	at	IN
cord-010499-yefxrj30	225	31	hungry	hungry	JJ
cord-010499-yefxrj30	225	32	codons	codon	NNS
cord-010499-yefxrj30	225	33	(	(	-LRB-
cord-010499-yefxrj30	225	34	Gallant	Gallant	NNP
cord-010499-yefxrj30	225	35	,	,	,
cord-010499-yefxrj30	225	36	1979	1979	CD
cord-010499-yefxrj30	225	37	;	;	:
cord-010499-yefxrj30	225	38	Cashel	Cashel	NNP
cord-010499-yefxrj30	225	39	and	and	CC
cord-010499-yefxrj30	225	40	Rudd	Rudd	NNP
cord-010499-yefxrj30	225	41	,	,	,
cord-010499-yefxrj30	225	42	1987	1987	CD
cord-010499-yefxrj30	225	43	;	;	:
cord-010499-yefxrj30	225	44	Parker	Parker	NNP
cord-010499-yefxrj30	225	45	.	.	.
cord-010499-yefxrj30	225	46	1989	1989	CD
cord-010499-yefxrj30	225	47	)	)	-RRB-
cord-010499-yefxrj30	225	48	.	.	.
cord-010499-yefxrj30	226	1	Subsequently	subsequently	RB
cord-010499-yefxrj30	226	2	,	,	,
cord-010499-yefxrj30	226	3	leftward	leftward	JJ
cord-010499-yefxrj30	226	4	slippage	slippage	NN
cord-010499-yefxrj30	226	5	of	of	IN
cord-010499-yefxrj30	226	6	the	the	DT
cord-010499-yefxrj30	226	7	phe	phe	NNP
cord-010499-yefxrj30	226	8	-	-	HYPH
cord-010499-yefxrj30	226	9	tRNA	tRNA	NNP
cord-010499-yefxrj30	226	10	in	in	IN
cord-010499-yefxrj30	226	11	the	the	DT
cord-010499-yefxrj30	226	12	A	A	NNP
cord-010499-yefxrj30	226	13	-	-	HYPH
cord-010499-yefxrj30	226	14	site	site	NN
cord-010499-yefxrj30	226	15	to	to	IN
cord-010499-yefxrj30	226	16	the	the	DT
cord-010499-yefxrj30	226	17	overiapping	overiappe	VBG
cord-010499-yefxrj30	226	18	UUU	UUU	NNP
cord-010499-yefxrj30	226	19	triplet	triplet	NN
cord-010499-yefxrj30	226	20	would	would	MD
cord-010499-yefxrj30	226	21	provide	provide	VB
cord-010499-yefxrj30	226	22	complementarity	complementarity	NN
cord-010499-yefxrj30	226	23	at	at	IN
cord-010499-yefxrj30	226	24	all	all	DT
cord-010499-yefxrj30	226	25	three	three	CD
cord-010499-yefxrj30	226	26	positions	position	NNS
cord-010499-yefxrj30	226	27	,	,	,
cord-010499-yefxrj30	226	28	and	and	CC
cord-010499-yefxrj30	226	29	thus	thus	RB
cord-010499-yefxrj30	226	30	improve	improve	VB
cord-010499-yefxrj30	226	31	stabiiity	stabiiity	NN
cord-010499-yefxrj30	226	32	.	.	.
cord-010499-yefxrj30	227	1	in	in	IN
cord-010499-yefxrj30	227	2	this	this	DT
cord-010499-yefxrj30	227	3	way	way	NN
cord-010499-yefxrj30	227	4	,	,	,
cord-010499-yefxrj30	227	5	an	an	DT
cord-010499-yefxrj30	227	6	initial	initial	JJ
cord-010499-yefxrj30	227	7	recognition	recognition	NN
cord-010499-yefxrj30	227	8	error	error	NN
cord-010499-yefxrj30	227	9	in	in	IN
cord-010499-yefxrj30	227	10	the	the	DT
cord-010499-yefxrj30	227	11	(	(	-LRB-
cord-010499-yefxrj30	227	12	0	0	NFP
cord-010499-yefxrj30	227	13	)	)	-RRB-
cord-010499-yefxrj30	227	14	reading	reading	NN
cord-010499-yefxrj30	227	15	frame	frame	NN
cord-010499-yefxrj30	227	16	could	could	MD
cord-010499-yefxrj30	227	17	be	be	VB
cord-010499-yefxrj30	227	18	resolved	resolve	VBN
cord-010499-yefxrj30	227	19	by	by	IN
cord-010499-yefxrj30	227	20	way	way	NN
cord-010499-yefxrj30	227	21	of	of	IN
cord-010499-yefxrj30	227	22	a	a	DT
cord-010499-yefxrj30	227	23	reading	reading	NN
cord-010499-yefxrj30	227	24	frame	frame	NN
cord-010499-yefxrj30	227	25	error	error	NN
cord-010499-yefxrj30	227	26	,	,	,
cord-010499-yefxrj30	227	27	an	an	DT
cord-010499-yefxrj30	227	28	example	example	NN
cord-010499-yefxrj30	227	29	of	of	IN
cord-010499-yefxrj30	227	30	what	what	WP
cord-010499-yefxrj30	227	31	has	have	VBZ
cord-010499-yefxrj30	227	32	elsewhere	elsewhere	RB
cord-010499-yefxrj30	227	33	been	be	VBN
cord-010499-yefxrj30	227	34	termed	term	VBN
cord-010499-yefxrj30	227	35	'	'	``
cord-010499-yefxrj30	227	36	error	error	NN
cord-010499-yefxrj30	227	37	coupiing	coupiing	NN
cord-010499-yefxrj30	227	38	'	'	''
cord-010499-yefxrj30	227	39	(	(	-LRB-
cord-010499-yefxrj30	227	40	Kuriand	Kuriand	NNP
cord-010499-yefxrj30	227	41	and	and	CC
cord-010499-yefxrj30	227	42	Gaiiant	Gaiiant	NNP
cord-010499-yefxrj30	227	43	.	.	.
cord-010499-yefxrj30	228	1	1986	1986	CD
cord-010499-yefxrj30	228	2	)	)	-RRB-
cord-010499-yefxrj30	228	3	.	.	.
cord-010499-yefxrj30	229	1	The	the	DT
cord-010499-yefxrj30	229	2	poi	poi	JJ
cord-010499-yefxrj30	229	3	gene	gene	NN
cord-010499-yefxrj30	229	4	product	product	NN
cord-010499-yefxrj30	229	5	expressed	express	VBN
cord-010499-yefxrj30	229	6	from	from	IN
cord-010499-yefxrj30	229	7	intact	intact	JJ
cord-010499-yefxrj30	229	8	HiV	HiV	NNP
cord-010499-yefxrj30	229	9	in	in	IN
cord-010499-yefxrj30	229	10	human	human	JJ
cord-010499-yefxrj30	229	11	host	host	NN
cord-010499-yefxrj30	229	12	cells	cell	NNS
cord-010499-yefxrj30	229	13	has	have	VBZ
cord-010499-yefxrj30	229	14	yet	yet	RB
cord-010499-yefxrj30	229	15	to	to	TO
cord-010499-yefxrj30	229	16	be	be	VB
cord-010499-yefxrj30	229	17	characterized	characterize	VBN
cord-010499-yefxrj30	229	18	at	at	IN
cord-010499-yefxrj30	229	19	the	the	DT
cord-010499-yefxrj30	229	20	amino	amino	NN
cord-010499-yefxrj30	229	21	acid	acid	NN
cord-010499-yefxrj30	229	22	sequence	sequence	NN
cord-010499-yefxrj30	229	23	level	level	NN
cord-010499-yefxrj30	229	24	.	.	.
cord-010499-yefxrj30	230	1	Consequently	consequently	RB
cord-010499-yefxrj30	230	2	,	,	,
cord-010499-yefxrj30	230	3	it	-PRON-	PRP
cord-010499-yefxrj30	230	4	is	be	VBZ
cord-010499-yefxrj30	230	5	unknown	unknown	JJ
cord-010499-yefxrj30	230	6	whether	whether	IN
cord-010499-yefxrj30	230	7	the	the	DT
cord-010499-yefxrj30	230	8	amino	amino	NN
cord-010499-yefxrj30	230	9	acid	acid	NN
cord-010499-yefxrj30	230	10	at	at	IN
cord-010499-yefxrj30	230	11	the	the	DT
cord-010499-yefxrj30	230	12	frameshift	frameshift	NN
cord-010499-yefxrj30	230	13	junction	junction	NNP
cord-010499-yefxrj30	230	14	is	be	VBZ
cord-010499-yefxrj30	230	15	ieucine	ieucine	JJ
cord-010499-yefxrj30	230	16	or	or	CC
cord-010499-yefxrj30	230	17	phenylaianine	phenylaianine	NNP
cord-010499-yefxrj30	230	18	(	(	-LRB-
cord-010499-yefxrj30	230	19	or	or	CC
cord-010499-yefxrj30	230	20	a	a	DT
cord-010499-yefxrj30	230	21	mixed	mixed	JJ
cord-010499-yefxrj30	230	22	population	population	NN
cord-010499-yefxrj30	230	23	)	)	-RRB-
cord-010499-yefxrj30	230	24	,	,	,
cord-010499-yefxrj30	230	25	and	and	CC
cord-010499-yefxrj30	230	26	it	-PRON-	PRP
cord-010499-yefxrj30	230	27	is	be	VBZ
cord-010499-yefxrj30	230	28	therefore	therefore	RB
cord-010499-yefxrj30	230	29	unknown	unknown	JJ
cord-010499-yefxrj30	230	30	which	which	WDT
cord-010499-yefxrj30	230	31	mode(s	mode(s	NN
cord-010499-yefxrj30	230	32	)	)	-RRB-
cord-010499-yefxrj30	230	33	of	of	IN
cord-010499-yefxrj30	230	34	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	230	35	operates	operate	NNS
cord-010499-yefxrj30	230	36	under	under	IN
cord-010499-yefxrj30	230	37	natural	natural	JJ
cord-010499-yefxrj30	230	38	conditions	condition	NNS
cord-010499-yefxrj30	230	39	.	.	.
cord-010499-yefxrj30	231	1	The	the	DT
cord-010499-yefxrj30	231	2	overlapping	overlap	VBG
cord-010499-yefxrj30	231	3	reading	reading	NN
cord-010499-yefxrj30	231	4	mechanism	mechanism	NN
cord-010499-yefxrj30	231	5	is	be	VBZ
cord-010499-yefxrj30	231	6	worth	worth	JJ
cord-010499-yefxrj30	231	7	bearing	bear	VBG
cord-010499-yefxrj30	231	8	in	in	IN
cord-010499-yefxrj30	231	9	mind	mind	NN
cord-010499-yefxrj30	231	10	because	because	IN
cord-010499-yefxrj30	231	11	of	of	IN
cord-010499-yefxrj30	231	12	the	the	DT
cord-010499-yefxrj30	231	13	obvious	obvious	JJ
cord-010499-yefxrj30	231	14	possibilities	possibility	NNS
cord-010499-yefxrj30	231	15	it	-PRON-	PRP
cord-010499-yefxrj30	231	16	presents	present	VBZ
cord-010499-yefxrj30	231	17	for	for	IN
cord-010499-yefxrj30	231	18	physiological	physiological	JJ
cord-010499-yefxrj30	231	19	controi	controi	NN
cord-010499-yefxrj30	231	20	.	.	.
cord-010499-yefxrj30	232	1	In	in	IN
cord-010499-yefxrj30	232	2	prokaryotic	prokaryotic	JJ
cord-010499-yefxrj30	232	3	systems	system	NNS
cord-010499-yefxrj30	232	4	,	,	,
cord-010499-yefxrj30	232	5	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	232	6	by	by	IN
cord-010499-yefxrj30	232	7	overlapping	overlap	VBG
cord-010499-yefxrj30	232	8	reading	reading	NN
cord-010499-yefxrj30	232	9	is	be	VBZ
cord-010499-yefxrj30	232	10	a	a	DT
cord-010499-yefxrj30	232	11	natural	natural	JJ
cord-010499-yefxrj30	232	12	outcome	outcome	NN
cord-010499-yefxrj30	232	13	of	of	IN
cord-010499-yefxrj30	232	14	imbalances	imbalance	NNS
cord-010499-yefxrj30	232	15	in	in	IN
cord-010499-yefxrj30	232	16	the	the	DT
cord-010499-yefxrj30	232	17	aminoacyl	aminoacyl	VBN
cord-010499-yefxrj30	232	18	-	-	HYPH
cord-010499-yefxrj30	232	19	tRNA	trna	NN
cord-010499-yefxrj30	232	20	pools	pool	NNS
cord-010499-yefxrj30	233	1	(	(	-LRB-
cord-010499-yefxrj30	233	2	Atkins	Atkins	NNP
cord-010499-yefxrj30	233	3	et	et	NNP
cord-010499-yefxrj30	233	4	ai	ai	NNP
cord-010499-yefxrj30	233	5	.	.	.
cord-010499-yefxrj30	233	6	1979	1979	CD
cord-010499-yefxrj30	233	7	;	;	.
cord-010499-yefxrj30	234	1	Gallant	gallant	JJ
cord-010499-yefxrj30	234	2	and	and	CC
cord-010499-yefxrj30	234	3	Foley	Foley	NNP
cord-010499-yefxrj30	234	4	.	.	.
cord-010499-yefxrj30	235	1	1980	1980	CD
cord-010499-yefxrj30	235	2	;	;	:
cord-010499-yefxrj30	235	3	Weiss	Weiss	NNP
cord-010499-yefxrj30	235	4	and	and	CC
cord-010499-yefxrj30	235	5	Gallant	Gallant	NNP
cord-010499-yefxrj30	235	6	,	,	,
cord-010499-yefxrj30	235	7	1983	1983	CD
cord-010499-yefxrj30	235	8	;	;	:
cord-010499-yefxrj30	235	9	1986	1986	CD
cord-010499-yefxrj30	235	10	;	;	:
cord-010499-yefxrj30	235	11	Kuriand	Kuriand	NNP
cord-010499-yefxrj30	235	12	and	and	CC
cord-010499-yefxrj30	235	13	Gallant	Gallant	NNP
cord-010499-yefxrj30	235	14	,	,	,
cord-010499-yefxrj30	235	15	1986	1986	CD
cord-010499-yefxrj30	235	16	;	;	:
cord-010499-yefxrj30	235	17	Bruce	Bruce	NNP
cord-010499-yefxrj30	235	18	et	et	NNP
cord-010499-yefxrj30	235	19	ai	ai	NNP
cord-010499-yefxrj30	235	20	.	.	.
cord-010499-yefxrj30	235	21	1986	1986	CD
cord-010499-yefxrj30	235	22	;	;	:
cord-010499-yefxrj30	235	23	Weiss	Weiss	NNP
cord-010499-yefxrj30	235	24	and	and	CC
cord-010499-yefxrj30	235	25	Gallant	Gallant	NNP
cord-010499-yefxrj30	235	26	.	.	.
cord-010499-yefxrj30	235	27	1986	1986	CD
cord-010499-yefxrj30	235	28	)	)	-RRB-
cord-010499-yefxrj30	235	29	.	.	.
cord-010499-yefxrj30	236	1	Our	-PRON-	PRP$
cord-010499-yefxrj30	236	2	present	present	JJ
cord-010499-yefxrj30	236	3	resuits	resuit	NNS
cord-010499-yefxrj30	236	4	demonstrate	demonstrate	VBP
cord-010499-yefxrj30	236	5	that	that	IN
cord-010499-yefxrj30	236	6	a	a	DT
cord-010499-yefxrj30	236	7	translational	translational	JJ
cord-010499-yefxrj30	236	8	frameshift	frameshift	NN
cord-010499-yefxrj30	236	9	signal	signal	NN
cord-010499-yefxrj30	236	10	from	from	IN
cord-010499-yefxrj30	236	11	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	236	12	can	can	MD
cord-010499-yefxrj30	236	13	be	be	VB
cord-010499-yefxrj30	236	14	reguiated	reguiate	VBN
cord-010499-yefxrj30	236	15	in	in	IN
cord-010499-yefxrj30	236	16	this	this	DT
cord-010499-yefxrj30	236	17	fashion	fashion	NN
cord-010499-yefxrj30	236	18	in	in	IN
cord-010499-yefxrj30	236	19	response	response	NN
cord-010499-yefxrj30	236	20	to	to	IN
cord-010499-yefxrj30	236	21	changing	change	VBG
cord-010499-yefxrj30	236	22	ieveis	ieveis	NNP
cord-010499-yefxrj30	236	23	of	of	IN
cord-010499-yefxrj30	236	24	leucyl	leucyl	NNP
cord-010499-yefxrj30	236	25	-	-	HYPH
cord-010499-yefxrj30	236	26	tRNA	tRNA	NNP
cord-010499-yefxrj30	236	27	.	.	.
cord-010499-yefxrj30	237	1	Similar	similar	JJ
cord-010499-yefxrj30	237	2	regulation	regulation	NN
cord-010499-yefxrj30	237	3	might	may	MD
cord-010499-yefxrj30	237	4	be	be	VB
cord-010499-yefxrj30	237	5	a	a	DT
cord-010499-yefxrj30	237	6	simpie	simpie	NN
cord-010499-yefxrj30	237	7	but	but	CC
cord-010499-yefxrj30	237	8	effective	effective	JJ
cord-010499-yefxrj30	237	9	metliod	metliod	NN
cord-010499-yefxrj30	237	10	for	for	IN
cord-010499-yefxrj30	237	11	establishing	establish	VBG
cord-010499-yefxrj30	237	12	physioiogical	physioiogical	JJ
cord-010499-yefxrj30	237	13	control	control	NN
cord-010499-yefxrj30	237	14	of	of	IN
cord-010499-yefxrj30	237	15	the	the	DT
cord-010499-yefxrj30	237	16	expression	expression	NN
cord-010499-yefxrj30	237	17	of	of	IN
cord-010499-yefxrj30	237	18	any	any	DT
cord-010499-yefxrj30	237	19	frameshifted	frameshifted	JJ
cord-010499-yefxrj30	237	20	gene	gene	NN
cord-010499-yefxrj30	237	21	.	.	.
cord-010499-yefxrj30	238	1	Many	many	JJ
cord-010499-yefxrj30	238	2	such	such	JJ
cord-010499-yefxrj30	238	3	genes	gene	NNS
cord-010499-yefxrj30	238	4	function	function	VBP
cord-010499-yefxrj30	238	5	to	to	TO
cord-010499-yefxrj30	238	6	replicate	replicate	VB
cord-010499-yefxrj30	238	7	and	and	CC
cord-010499-yefxrj30	238	8	spread	spread	VB
cord-010499-yefxrj30	238	9	viruses	virus	NNS
cord-010499-yefxrj30	238	10	,	,	,
cord-010499-yefxrj30	238	11	transposable	transposable	JJ
cord-010499-yefxrj30	238	12	elements	element	NNS
cord-010499-yefxrj30	238	13	,	,	,
cord-010499-yefxrj30	238	14	and	and	CC
cord-010499-yefxrj30	238	15	retroviruses	retrovirus	NNS
cord-010499-yefxrj30	238	16	(	(	-LRB-
cord-010499-yefxrj30	238	17	reviewed	review	VBN
cord-010499-yefxrj30	238	18	by	by	IN
cord-010499-yefxrj30	238	19	Hatfield	Hatfield	NNP
cord-010499-yefxrj30	238	20	and	and	CC
cord-010499-yefxrj30	238	21	Oroszlan	Oroszlan	NNP
cord-010499-yefxrj30	238	22	,	,	,
cord-010499-yefxrj30	238	23	1990	1990	CD
cord-010499-yefxrj30	238	24	;	;	:
cord-010499-yefxrj30	238	25	Cattaneo	Cattaneo	NNP
cord-010499-yefxrj30	238	26	.	.	.
cord-010499-yefxrj30	238	27	1989	1989	CD
cord-010499-yefxrj30	238	28	)	)	-RRB-
cord-010499-yefxrj30	238	29	.	.	.
cord-010499-yefxrj30	239	1	In	in	IN
cord-010499-yefxrj30	239	2	these	these	DT
cord-010499-yefxrj30	239	3	cases	case	NNS
cord-010499-yefxrj30	239	4	,	,	,
cord-010499-yefxrj30	239	5	ribosome	ribosome	NN
cord-010499-yefxrj30	239	6	frameshifting	frameshifting	NN
cord-010499-yefxrj30	239	7	during	during	IN
cord-010499-yefxrj30	239	8	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	239	9	-	-	HYPH
cord-010499-yefxrj30	239	10	tRNA	trna	NN
cord-010499-yefxrj30	239	11	imbalance	imbalance	NN
cord-010499-yefxrj30	239	12	might	may	MD
cord-010499-yefxrj30	239	13	represent	represent	VB
cord-010499-yefxrj30	239	14	a	a	DT
cord-010499-yefxrj30	239	15	mechanism	mechanism	NN
cord-010499-yefxrj30	239	16	for	for	IN
cord-010499-yefxrj30	239	17	iinking	iinke	VBG
cord-010499-yefxrj30	239	18	element	element	NN
cord-010499-yefxrj30	239	19	movement	movement	NN
cord-010499-yefxrj30	239	20	to	to	IN
cord-010499-yefxrj30	239	21	the	the	DT
cord-010499-yefxrj30	239	22	state	state	NN
cord-010499-yefxrj30	239	23	of	of	IN
cord-010499-yefxrj30	239	24	the	the	DT
cord-010499-yefxrj30	239	25	celiuiar	celiuiar	NN
cord-010499-yefxrj30	239	26	economy	economy	NN
cord-010499-yefxrj30	239	27	.	.	.
cord-010499-yefxrj30	240	1	The	the	DT
cord-010499-yefxrj30	240	2	degree	degree	NN
cord-010499-yefxrj30	240	3	of	of	IN
cord-010499-yefxrj30	240	4	aminoacylation	aminoacylation	NN
cord-010499-yefxrj30	240	5	of	of	IN
cord-010499-yefxrj30	240	6	tRNAs	tRNAs	NNPS
cord-010499-yefxrj30	240	7	provides	provide	VBZ
cord-010499-yefxrj30	240	8	a	a	DT
cord-010499-yefxrj30	240	9	sensitive	sensitive	JJ
cord-010499-yefxrj30	240	10	difference	difference	NN
cord-010499-yefxrj30	240	11	signal	signal	NN
cord-010499-yefxrj30	240	12	of	of	IN
cord-010499-yefxrj30	240	13	ceilular	ceilular	NNP
cord-010499-yefxrj30	240	14	activity	activity	NN
cord-010499-yefxrj30	240	15	.	.	.
cord-010499-yefxrj30	241	1	Anabolism	anabolism	NN
cord-010499-yefxrj30	241	2	generates	generate	VBZ
cord-010499-yefxrj30	241	3	the	the	DT
cord-010499-yefxrj30	241	4	amino	amino	NN
cord-010499-yefxrj30	241	5	acids	acid	NNS
cord-010499-yefxrj30	241	6	which	which	WDT
cord-010499-yefxrj30	241	7	charge	charge	VBP
cord-010499-yefxrj30	241	8	the	the	DT
cord-010499-yefxrj30	241	9	tRNAs	trna	NNS
cord-010499-yefxrj30	241	10	,	,	,
cord-010499-yefxrj30	241	11	while	while	IN
cord-010499-yefxrj30	241	12	translation	translation	NN
cord-010499-yefxrj30	241	13	drains	drain	VBZ
cord-010499-yefxrj30	241	14	these	these	DT
cord-010499-yefxrj30	241	15	amino	amino	JJ
cord-010499-yefxrj30	241	16	acids	acid	NNS
cord-010499-yefxrj30	241	17	into	into	IN
cord-010499-yefxrj30	241	18	growing	grow	VBG
cord-010499-yefxrj30	241	19	proteins	protein	NNS
cord-010499-yefxrj30	241	20	.	.	.
cord-010499-yefxrj30	242	1	Hence	hence	RB
cord-010499-yefxrj30	242	2	,	,	,
cord-010499-yefxrj30	242	3	the	the	DT
cord-010499-yefxrj30	242	4	tRNA	trna	NN
cord-010499-yefxrj30	242	5	charging	charge	VBG
cord-010499-yefxrj30	242	6	levei	levei	NNP
cord-010499-yefxrj30	242	7	reflects	reflect	VBZ
cord-010499-yefxrj30	242	8	the	the	DT
cord-010499-yefxrj30	242	9	balance	balance	NN
cord-010499-yefxrj30	242	10	of	of	IN
cord-010499-yefxrj30	242	11	these	these	DT
cord-010499-yefxrj30	242	12	two	two	CD
cord-010499-yefxrj30	242	13	flows	flow	NNS
cord-010499-yefxrj30	242	14	,	,	,
cord-010499-yefxrj30	242	15	in	in	IN
cord-010499-yefxrj30	242	16	bacterial	bacterial	JJ
cord-010499-yefxrj30	242	17	celis	celis	NNP
cord-010499-yefxrj30	242	18	,	,	,
cord-010499-yefxrj30	242	19	tRNA	tRNA	NNP
cord-010499-yefxrj30	242	20	aminoacylation	aminoacylation	NN
cord-010499-yefxrj30	242	21	levels	level	NNS
cord-010499-yefxrj30	242	22	operate	operate	VBP
cord-010499-yefxrj30	242	23	both	both	DT
cord-010499-yefxrj30	242	24	specific	specific	JJ
cord-010499-yefxrj30	242	25	attenuation	attenuation	NN
cord-010499-yefxrj30	242	26	control	control	NN
cord-010499-yefxrj30	242	27	circuits	circuit	NNS
cord-010499-yefxrj30	242	28	(	(	-LRB-
cord-010499-yefxrj30	242	29	Landick	Landick	NNP
cord-010499-yefxrj30	242	30	and	and	CC
cord-010499-yefxrj30	242	31	Yanofsky	Yanofsky	NNP
cord-010499-yefxrj30	242	32	,	,	,
cord-010499-yefxrj30	242	33	1987	1987	CD
cord-010499-yefxrj30	242	34	)	)	-RRB-
cord-010499-yefxrj30	242	35	and	and	CC
cord-010499-yefxrj30	242	36	the	the	DT
cord-010499-yefxrj30	242	37	highly	highly	RB
cord-010499-yefxrj30	242	38	pleiotropic	pleiotropic	JJ
cord-010499-yefxrj30	242	39	stringent	stringent	JJ
cord-010499-yefxrj30	242	40	controi	controi	NN
cord-010499-yefxrj30	242	41	system	system	NN
cord-010499-yefxrj30	242	42	(	(	-LRB-
cord-010499-yefxrj30	242	43	Gallant	Gallant	NNP
cord-010499-yefxrj30	242	44	,	,	,
cord-010499-yefxrj30	242	45	1979	1979	CD
cord-010499-yefxrj30	242	46	;	;	:
cord-010499-yefxrj30	242	47	Cashel	Cashel	NNP
cord-010499-yefxrj30	242	48	and	and	CC
cord-010499-yefxrj30	242	49	Rudd	Rudd	NNP
cord-010499-yefxrj30	242	50	.	.	.
cord-010499-yefxrj30	242	51	1987	1987	CD
cord-010499-yefxrj30	242	52	)	)	-RRB-
cord-010499-yefxrj30	242	53	.	.	.
cord-010499-yefxrj30	243	1	and	and	CC
cord-010499-yefxrj30	243	2	may	may	MD
cord-010499-yefxrj30	243	3	regulate	regulate	VB
cord-010499-yefxrj30	243	4	the	the	DT
cord-010499-yefxrj30	243	5	expression	expression	NN
cord-010499-yefxrj30	243	6	of	of	IN
cord-010499-yefxrj30	243	7	individual	individual	JJ
cord-010499-yefxrj30	243	8	translation	translation	NN
cord-010499-yefxrj30	243	9	factor	factor	NN
cord-010499-yefxrj30	243	10	genes	gene	NNS
cord-010499-yefxrj30	243	11	(	(	-LRB-
cord-010499-yefxrj30	243	12	Grunberg	Grunberg	NNP
cord-010499-yefxrj30	243	13	-	-	HYPH
cord-010499-yefxrj30	243	14	Manago	Manago	NNP
cord-010499-yefxrj30	243	15	,	,	,
cord-010499-yefxrj30	243	16	1987	1987	CD
cord-010499-yefxrj30	243	17	)	)	-RRB-
cord-010499-yefxrj30	243	18	.	.	.
cord-010499-yefxrj30	244	1	This	this	DT
cord-010499-yefxrj30	244	2	speculation	speculation	NN
cord-010499-yefxrj30	244	3	might	may	MD
cord-010499-yefxrj30	244	4	provide	provide	VB
cord-010499-yefxrj30	244	5	a	a	DT
cord-010499-yefxrj30	244	6	rationale	rationale	NN
cord-010499-yefxrj30	244	7	for	for	IN
cord-010499-yefxrj30	244	8	the	the	DT
cord-010499-yefxrj30	244	9	various	various	JJ
cord-010499-yefxrj30	244	10	different	different	JJ
cord-010499-yefxrj30	244	11	shifty	shifty	JJ
cord-010499-yefxrj30	244	12	sequences	sequence	NNS
cord-010499-yefxrj30	244	13	found	find	VBN
cord-010499-yefxrj30	244	14	in	in	IN
cord-010499-yefxrj30	244	15	the	the	DT
cord-010499-yefxrj30	244	16	gag	gag	NN
cord-010499-yefxrj30	244	17	-	-	HYPH
cord-010499-yefxrj30	244	18	pol	pol	NN
cord-010499-yefxrj30	244	19	aj\6	aj\6	NNP
cord-010499-yefxrj30	244	20	gagpro	gagpro	JJ
cord-010499-yefxrj30	244	21	-	-	HYPH
cord-010499-yefxrj30	244	22	pol	pol	JJ
cord-010499-yefxrj30	244	23	overiaps	overiap	NNS
cord-010499-yefxrj30	244	24	of	of	IN
cord-010499-yefxrj30	244	25	different	different	JJ
cord-010499-yefxrj30	244	26	retroviruses	retrovirus	NNS
cord-010499-yefxrj30	244	27	,	,	,
cord-010499-yefxrj30	244	28	and	and	CC
cord-010499-yefxrj30	244	29	the	the	DT
cord-010499-yefxrj30	244	30	comparable	comparable	JJ
cord-010499-yefxrj30	244	31	regions	region	NNS
cord-010499-yefxrj30	244	32	of	of	IN
cord-010499-yefxrj30	244	33	different	different	JJ
cord-010499-yefxrj30	244	34	coronaviruses	coronaviruse	NNS
cord-010499-yefxrj30	244	35	.	.	.
cord-010499-yefxrj30	245	1	Perhaps	perhaps	RB
cord-010499-yefxrj30	245	2	each	each	DT
cord-010499-yefxrj30	245	3	unique	unique	JJ
cord-010499-yefxrj30	245	4	shifty	shifty	JJ
cord-010499-yefxrj30	245	5	sequence	sequence	NN
cord-010499-yefxrj30	245	6	has	have	VBZ
cord-010499-yefxrj30	245	7	been	be	VBN
cord-010499-yefxrj30	245	8	evoiutionariiy	evoiutionariiy	JJ
cord-010499-yefxrj30	245	9	optimized	optimize	VBN
cord-010499-yefxrj30	245	10	to	to	TO
cord-010499-yefxrj30	245	11	respond	respond	VB
cord-010499-yefxrj30	245	12	to	to	IN
cord-010499-yefxrj30	245	13	a	a	DT
cord-010499-yefxrj30	245	14	tRNA	tRNA	NNP
cord-010499-yefxrj30	245	15	deficiency	deficiency	NN
cord-010499-yefxrj30	245	16	that	that	WDT
cord-010499-yefxrj30	245	17	is	be	VBZ
cord-010499-yefxrj30	245	18	the	the	DT
cord-010499-yefxrj30	245	19	most	most	RBS
cord-010499-yefxrj30	245	20	sensitive	sensitive	JJ
cord-010499-yefxrj30	245	21	difference	difference	NN
cord-010499-yefxrj30	245	22	signal	signal	NN
cord-010499-yefxrj30	245	23	for	for	IN
cord-010499-yefxrj30	245	24	its	-PRON-	PRP$
cord-010499-yefxrj30	245	25	particular	particular	JJ
cord-010499-yefxrj30	245	26	host	host	NN
cord-010499-yefxrj30	245	27	ceils	ceil	NNS
cord-010499-yefxrj30	245	28	.	.	.
cord-010499-yefxrj30	246	1	Likewise	likewise	RB
cord-010499-yefxrj30	246	2	,	,	,
cord-010499-yefxrj30	246	3	evoiutionary	evoiutionary	JJ
cord-010499-yefxrj30	246	4	pressure	pressure	NN
cord-010499-yefxrj30	246	5	to	to	TO
cord-010499-yefxrj30	246	6	maintain	maintain	VB
cord-010499-yefxrj30	246	7	a	a	DT
cord-010499-yefxrj30	246	8	response	response	NN
cord-010499-yefxrj30	246	9	to	to	IN
cord-010499-yefxrj30	246	10	a	a	DT
cord-010499-yefxrj30	246	11	cell	cell	NN
cord-010499-yefxrj30	246	12	-	-	HYPH
cord-010499-yefxrj30	246	13	specific	specific	JJ
cord-010499-yefxrj30	246	14	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	246	15	-	-	HYPH
cord-010499-yefxrj30	246	16	tRNA	trna	NN
cord-010499-yefxrj30	246	17	signal	signal	NN
cord-010499-yefxrj30	246	18	might	may	MD
cord-010499-yefxrj30	246	19	also	also	RB
cord-010499-yefxrj30	246	20	explain	explain	VB
cord-010499-yefxrj30	246	21	why	why	WRB
cord-010499-yefxrj30	246	22	retroviruses	retrovirus	NNS
cord-010499-yefxrj30	246	23	maintain	maintain	VB
cord-010499-yefxrj30	246	24	non	non	JJ
cord-010499-yefxrj30	246	25	-	-	JJ
cord-010499-yefxrj30	246	26	optimal	optimal	JJ
cord-010499-yefxrj30	246	27	translational	translational	JJ
cord-010499-yefxrj30	246	28	frameshift	frameshift	NN
cord-010499-yefxrj30	246	29	sequences	sequence	NNS
cord-010499-yefxrj30	246	30	which	which	WDT
cord-010499-yefxrj30	246	31	must	must	MD
cord-010499-yefxrj30	246	32	in	in	IN
cord-010499-yefxrj30	246	33	some	some	DT
cord-010499-yefxrj30	246	34	cases	case	NNS
cord-010499-yefxrj30	246	35	be	be	VB
cord-010499-yefxrj30	246	36	augmented	augment	VBN
cord-010499-yefxrj30	246	37	by	by	IN
cord-010499-yefxrj30	246	38	baroque	baroque	NN
cord-010499-yefxrj30	246	39	mRNA	mRNA	NNP
cord-010499-yefxrj30	246	40	secondary	secondary	JJ
cord-010499-yefxrj30	246	41	structures	structure	NNS
cord-010499-yefxrj30	246	42	downstream	downstream	RB
cord-010499-yefxrj30	247	1	(	(	-LRB-
cord-010499-yefxrj30	247	2	Weiss	Weiss	NNP
cord-010499-yefxrj30	247	3	et	et	NNP
cord-010499-yefxrj30	247	4	ai	ai	NNP
cord-010499-yefxrj30	247	5	.	.	.
cord-010499-yefxrj30	247	6	1989	1989	CD
cord-010499-yefxrj30	247	7	)	)	-RRB-
cord-010499-yefxrj30	247	8	.	.	.
cord-010499-yefxrj30	248	1	Finally	finally	RB
cord-010499-yefxrj30	248	2	,	,	,
cord-010499-yefxrj30	248	3	we	-PRON-	PRP
cord-010499-yefxrj30	248	4	might	may	MD
cord-010499-yefxrj30	248	5	note	note	VB
cord-010499-yefxrj30	248	6	that	that	IN
cord-010499-yefxrj30	248	7	our	-PRON-	PRP$
cord-010499-yefxrj30	248	8	data	datum	NNS
cord-010499-yefxrj30	248	9	do	do	VBP
cord-010499-yefxrj30	248	10	not	not	RB
cord-010499-yefxrj30	248	11	distinguish	distinguish	VB
cord-010499-yefxrj30	248	12	between	between	IN
cord-010499-yefxrj30	248	13	a	a	DT
cord-010499-yefxrj30	248	14	simultaneous	simultaneous	JJ
cord-010499-yefxrj30	248	15	slippage	slippage	NN
cord-010499-yefxrj30	248	16	mechanism	mechanism	NN
cord-010499-yefxrj30	248	17	at	at	IN
cord-010499-yefxrj30	248	18	the	the	DT
cord-010499-yefxrj30	248	19	leucine	leucine	NN
cord-010499-yefxrj30	248	20	codon	codon	NN
cord-010499-yefxrj30	248	21	(	(	-LRB-
cord-010499-yefxrj30	248	22	as	as	IN
cord-010499-yefxrj30	248	23	proposed	propose	VBN
cord-010499-yefxrj30	248	24	by	by	IN
cord-010499-yefxrj30	248	25	Jacks	Jacks	NNP
cord-010499-yefxrj30	248	26	and	and	CC
cord-010499-yefxrj30	248	27	Varmus	Varmus	NNP
cord-010499-yefxrj30	248	28	)	)	-RRB-
cord-010499-yefxrj30	248	29	and	and	CC
cord-010499-yefxrj30	248	30	an	an	DT
cord-010499-yefxrj30	248	31	overlapping	overlap	VBG
cord-010499-yefxrj30	248	32	reading	reading	NN
cord-010499-yefxrj30	248	33	mechanism	mechanism	NN
cord-010499-yefxrj30	248	34	at	at	IN
cord-010499-yefxrj30	248	35	the	the	DT
cord-010499-yefxrj30	248	36	next	next	JJ
cord-010499-yefxrj30	248	37	codon	codon	NN
cord-010499-yefxrj30	248	38	.	.	.
cord-010499-yefxrj30	249	1	If	if	IN
cord-010499-yefxrj30	249	2	ribosomes	ribosome	NNS
cord-010499-yefxrj30	249	3	in	in	IN
cord-010499-yefxrj30	249	4	unstarved	unstarved	JJ
cord-010499-yefxrj30	249	5	cells	cell	NNS
cord-010499-yefxrj30	249	6	paused	pause	VBD
cord-010499-yefxrj30	249	7	at	at	IN
cord-010499-yefxrj30	249	8	the	the	DT
cord-010499-yefxrj30	249	9	GGG	GGG	NNP
cord-010499-yefxrj30	249	10	codon	codon	NN
cord-010499-yefxrj30	249	11	following	follow	VBG
cord-010499-yefxrj30	249	12	the	the	DT
cord-010499-yefxrj30	249	13	leucine	leucine	NN
cord-010499-yefxrj30	249	14	codon	codon	NN
cord-010499-yefxrj30	249	15	,	,	,
cord-010499-yefxrj30	249	16	then	then	RB
cord-010499-yefxrj30	249	17	arg	arg	NN
cord-010499-yefxrj30	249	18	-	-	HYPH
cord-010499-yefxrj30	249	19	tRNA	tRNA	NNP
cord-010499-yefxrj30	249	20	could	could	MD
cord-010499-yefxrj30	249	21	enter	enter	VB
cord-010499-yefxrj30	249	22	by	by	IN
cord-010499-yefxrj30	249	23	overlapping	overlap	VBG
cord-010499-yefxrj30	249	24	reading	reading	NN
cord-010499-yefxrj30	249	25	and	and	CC
cord-010499-yefxrj30	249	26	shift	shift	VB
cord-010499-yefxrj30	249	27	the	the	DT
cord-010499-yefxrj30	249	28	reading	reading	NN
cord-010499-yefxrj30	249	29	frame	frame	NN
cord-010499-yefxrj30	249	30	leftward	leftward	RB
cord-010499-yefxrj30	249	31	(	(	-LRB-
cord-010499-yefxrj30	249	32	see	see	VB
cord-010499-yefxrj30	249	33	Fig	Fig	NNP
cord-010499-yefxrj30	249	34	.	.	NNP
cord-010499-yefxrj30	249	35	4	4	CD
cord-010499-yefxrj30	249	36	)	)	-RRB-
cord-010499-yefxrj30	249	37	.	.	.
cord-010499-yefxrj30	250	1	The	the	DT
cord-010499-yefxrj30	250	2	amino	amino	NN
cord-010499-yefxrj30	250	3	acid	acid	NN
cord-010499-yefxrj30	250	4	sequence	sequence	NN
cord-010499-yefxrj30	250	5	in	in	IN
cord-010499-yefxrj30	250	6	this	this	DT
cord-010499-yefxrj30	250	7	case	case	NN
cord-010499-yefxrj30	250	8	would	would	MD
cord-010499-yefxrj30	250	9	be	be	VB
cord-010499-yefxrj30	250	10	exactly	exactly	RB
cord-010499-yefxrj30	250	11	that	that	WDT
cord-010499-yefxrj30	250	12	ascribed	ascribe	VBN
cord-010499-yefxrj30	250	13	to	to	IN
cord-010499-yefxrj30	250	14	simultaneous	simultaneous	JJ
cord-010499-yefxrj30	250	15	slippage	slippage	NN
cord-010499-yefxrj30	250	16	,	,	,
cord-010499-yefxrj30	250	17	and	and	CC
cord-010499-yefxrj30	250	18	which	which	WDT
cord-010499-yefxrj30	250	19	we	-PRON-	PRP
cord-010499-yefxrj30	250	20	have	have	VBP
cord-010499-yefxrj30	250	21	demonstrated	demonstrate	VBN
cord-010499-yefxrj30	250	22	in	in	IN
cord-010499-yefxrj30	250	23	unstan	unstan	NNP
cord-010499-yefxrj30	250	24	/	/	SYM
cord-010499-yefxrj30	250	25	ed	ed	NNP
cord-010499-yefxrj30	250	26	E.	E.	NNP
cord-010499-yefxrj30	250	27	coli	coli	NNS
cord-010499-yefxrj30	250	28	cells	cell	NNS
cord-010499-yefxrj30	250	29	.	.	.
cord-010499-yefxrj30	251	1	We	-PRON-	PRP
cord-010499-yefxrj30	251	2	have	have	VBP
cord-010499-yefxrj30	251	3	no	no	DT
cord-010499-yefxrj30	251	4	independent	independent	JJ
cord-010499-yefxrj30	251	5	reason	reason	NN
cord-010499-yefxrj30	251	6	to	to	TO
cord-010499-yefxrj30	251	7	expect	expect	VB
cord-010499-yefxrj30	251	8	ribosome	ribosome	NN
cord-010499-yefxrj30	251	9	stalling	stall	VBG
cord-010499-yefxrj30	251	10	at	at	IN
cord-010499-yefxrj30	251	11	the	the	DT
cord-010499-yefxrj30	251	12	GGG	GGG	NNP
cord-010499-yefxrj30	251	13	codon	codon	NN
cord-010499-yefxrj30	251	14	in	in	IN
cord-010499-yefxrj30	251	15	growing	grow	VBG
cord-010499-yefxrj30	251	16	celis	celis	NNP
cord-010499-yefxrj30	251	17	,	,	,
cord-010499-yefxrj30	251	18	except	except	IN
cord-010499-yefxrj30	251	19	that	that	IN
cord-010499-yefxrj30	251	20	it	-PRON-	PRP
cord-010499-yefxrj30	251	21	is	be	VBZ
cord-010499-yefxrj30	251	22	a	a	DT
cord-010499-yefxrj30	251	23	rare	rare	JJ
cord-010499-yefxrj30	251	24	codon	codon	NN
cord-010499-yefxrj30	251	25	and	and	CC
cord-010499-yefxrj30	251	26	caiis	caii	VBN
cord-010499-yefxrj30	251	27	for	for	IN
cord-010499-yefxrj30	251	28	a	a	DT
cord-010499-yefxrj30	251	29	rare	rare	JJ
cord-010499-yefxrj30	251	30	tRNA	trna	NN
cord-010499-yefxrj30	251	31	.	.	.
cord-010499-yefxrj30	251	32	Experiments	experiment	NNS
cord-010499-yefxrj30	251	33	designed	design	VBN
cord-010499-yefxrj30	251	34	to	to	TO
cord-010499-yefxrj30	251	35	investigate	investigate	VB
cord-010499-yefxrj30	251	36	this	this	DT
cord-010499-yefxrj30	251	37	possibiiity	possibiiity	NN
cord-010499-yefxrj30	251	38	are	be	VBP
cord-010499-yefxrj30	251	39	under	under	IN
cord-010499-yefxrj30	251	40	way	way	NN
cord-010499-yefxrj30	251	41	.	.	.
cord-010499-yefxrj30	252	1	Frameshift	frameshift	NN
cord-010499-yefxrj30	252	2	alleles	allele	NNS
cord-010499-yefxrj30	252	3	were	be	VBD
cord-010499-yefxrj30	252	4	constructed	construct	VBN
cord-010499-yefxrj30	252	5	by	by	IN
cord-010499-yefxrj30	252	6	modification	modification	NN
cord-010499-yefxrj30	252	7	of	of	IN
cord-010499-yefxrj30	252	8	the	the	DT
cord-010499-yefxrj30	252	9	plasmid	plasmid	NN
cord-010499-yefxrj30	252	10	vector	vector	NN
cord-010499-yefxrj30	252	11	pBWIIOO	pBWIIOO	NNP
cord-010499-yefxrj30	252	12	.	.	.
cord-010499-yefxrj30	253	1	pBWIlOO	pBWIlOO	NNP
cord-010499-yefxrj30	253	2	,	,	,
cord-010499-yefxrj30	253	3	a	a	DT
cord-010499-yefxrj30	253	4	kind	kind	NN
cord-010499-yefxrj30	253	5	of	of	IN
cord-010499-yefxrj30	253	6	gift	gift	NN
cord-010499-yefxrj30	253	7	of	of	IN
cord-010499-yefxrj30	253	8	Bob	Bob	NNP
cord-010499-yefxrj30	253	9	Weiss	Weiss	NNP
cord-010499-yefxrj30	253	10	,	,	,
cord-010499-yefxrj30	253	11	is	be	VBZ
cord-010499-yefxrj30	253	12	a	a	DT
cord-010499-yefxrj30	253	13	modified	modify	VBN
cord-010499-yefxrj30	253	14	pBR322	pbr322	CD
cord-010499-yefxrj30	253	15	in	in	IN
cord-010499-yefxrj30	253	16	which	which	WDT
cord-010499-yefxrj30	253	17	nucleotides	nucleotide	NNS
cord-010499-yefxrj30	253	18	1	1	CD
cord-010499-yefxrj30	253	19	-	-	SYM
cord-010499-yefxrj30	253	20	1417	1417	CD
cord-010499-yefxrj30	253	21	were	be	VBD
cord-010499-yefxrj30	253	22	replaced	replace	VBN
cord-010499-yefxrj30	253	23	by	by	IN
cord-010499-yefxrj30	253	24	nucleotides	nucleotide	NNS
cord-010499-yefxrj30	253	25	1	1	CD
cord-010499-yefxrj30	253	26	-	-	CD
cord-010499-yefxrj30	253	27	4625	4625	CD
cord-010499-yefxrj30	254	1	(	(	-LRB-
cord-010499-yefxrj30	254	2	NIH	NIH	NNP
cord-010499-yefxrj30	254	3	GenBank	GenBank	NNP
cord-010499-yefxrj30	254	4	co	co	NN
cord-010499-yefxrj30	254	5	-	-	JJ
cord-010499-yefxrj30	254	6	ordinates	ordinate	NNS
cord-010499-yefxrj30	254	7	)	)	-RRB-
cord-010499-yefxrj30	254	8	of	of	IN
cord-010499-yefxrj30	254	9	the	the	DT
cord-010499-yefxrj30	254	10	E	e	NN
cord-010499-yefxrj30	254	11	coli	coli	NNS
cord-010499-yefxrj30	254	12	lac	lac	NNP
cord-010499-yefxrj30	254	13	operon	operon	NN
cord-010499-yefxrj30	254	14	.	.	.
cord-010499-yefxrj30	255	1	The	the	DT
cord-010499-yefxrj30	255	2	lac	lac	NN
cord-010499-yefxrj30	255	3	operon	operon	NN
cord-010499-yefxrj30	255	4	fragment	fragment	NN
cord-010499-yefxrj30	255	5	has	have	VBZ
cord-010499-yefxrj30	255	6	been	be	VBN
cord-010499-yefxrj30	255	7	modified	modify	VBN
cord-010499-yefxrj30	255	8	by	by	IN
cord-010499-yefxrj30	255	9	the	the	DT
cord-010499-yefxrj30	255	10	deletion	deletion	NN
cord-010499-yefxrj30	255	11	of	of	IN
cord-010499-yefxrj30	255	12	nucleotides	nucleotide	NNS
cord-010499-yefxrj30	255	13	641	641	CD
cord-010499-yefxrj30	255	14	-	-	HYPH
cord-010499-yefxrj30	255	15	1070	1070	CD
cord-010499-yefxrj30	255	16	,	,	,
cord-010499-yefxrj30	255	17	the	the	DT
cord-010499-yefxrj30	255	18	removal	removal	NN
cord-010499-yefxrj30	255	19	of	of	IN
cord-010499-yefxrj30	255	20	the	the	DT
cord-010499-yefxrj30	255	21	natural	natural	JJ
cord-010499-yefxrj30	255	22	EcoRI	ecori	NN
cord-010499-yefxrj30	255	23	site	site	NN
cord-010499-yefxrj30	255	24	within	within	IN
cord-010499-yefxrj30	255	25	the	the	DT
cord-010499-yefxrj30	255	26	/acZ	/acZ	NNP
cord-010499-yefxrj30	255	27	gene	gene	NN
cord-010499-yefxrj30	255	28	,	,	,
cord-010499-yefxrj30	255	29	and	and	CC
cord-010499-yefxrj30	255	30	by	by	IN
cord-010499-yefxrj30	255	31	the	the	DT
cord-010499-yefxrj30	255	32	addition	addition	NN
cord-010499-yefxrj30	255	33	of	of	IN
cord-010499-yefxrj30	255	34	the	the	DT
cord-010499-yefxrj30	255	35	pUC9	pUC9	NNP
cord-010499-yefxrj30	255	36	polylinker	polylinker	NN
cord-010499-yefxrj30	255	37	(	(	-LRB-
cord-010499-yefxrj30	255	38	Vieira	Vieira	NNP
cord-010499-yefxrj30	255	39	and	and	CC
cord-010499-yefxrj30	255	40	Messing	Messing	NNP
cord-010499-yefxrj30	255	41	,	,	,
cord-010499-yefxrj30	255	42	1982	1982	CD
cord-010499-yefxrj30	255	43	)	)	-RRB-
cord-010499-yefxrj30	255	44	between	between	IN
cord-010499-yefxrj30	255	45	codons	codon	NNS
cord-010499-yefxrj30	255	46	4	4	CD
cord-010499-yefxrj30	255	47	and	and	CC
cord-010499-yefxrj30	255	48	5	5	CD
cord-010499-yefxrj30	255	49	.	.	.
cord-010499-yefxrj30	256	1	The	the	DT
cord-010499-yefxrj30	256	2	resultant	resultant	JJ
cord-010499-yefxrj30	256	3	pBWIlOO	pbwiloo	NN
cord-010499-yefxrj30	256	4	is	be	VBZ
cord-010499-yefxrj30	256	5	Lad	Lad	NNP
cord-010499-yefxrj30	256	6	Z*Y"A	Z*Y"A	NNP
cord-010499-yefxrj30	256	7	,	,	,
cord-010499-yefxrj30	256	8	and	and	CC
cord-010499-yefxrj30	256	9	confers	confer	VBZ
cord-010499-yefxrj30	256	10	resistance	resistance	NN
cord-010499-yefxrj30	256	11	to	to	IN
cord-010499-yefxrj30	256	12	ampicillin	ampicillin	NN
cord-010499-yefxrj30	256	13	.	.	.
cord-010499-yefxrj30	257	1	In	in	IN
cord-010499-yefxrj30	257	2	typical	typical	JJ
cord-010499-yefxrj30	257	3	constructions	construction	NNS
cord-010499-yefxrj30	257	4	,	,	,
cord-010499-yefxrj30	257	5	about	about	RB
cord-010499-yefxrj30	257	6	1	1	CD
cord-010499-yefxrj30	257	7	jig	jig	NN
cord-010499-yefxrj30	257	8	of	of	IN
cord-010499-yefxrj30	257	9	pBWIlOO	pBWIlOO	NNP
cord-010499-yefxrj30	257	10	was	be	VBD
cord-010499-yefxrj30	257	11	cut	cut	VBN
cord-010499-yefxrj30	257	12	to	to	IN
cord-010499-yefxrj30	257	13	completion	completion	NN
cord-010499-yefxrj30	257	14	with	with	IN
cord-010499-yefxrj30	257	15	restriction	restriction	NN
cord-010499-yefxrj30	257	16	endonucleases	endonuclease	NNS
cord-010499-yefxrj30	257	17	H	h	NN
cord-010499-yefxrj30	257	18	/	/	SYM
cord-010499-yefxrj30	257	19	ndlll	ndlll	NN
cord-010499-yefxrj30	257	20	and	and	CC
cord-010499-yefxrj30	257	21	SamHI	SamHI	NNP
cord-010499-yefxrj30	258	1	(	(	-LRB-
cord-010499-yefxrj30	258	2	Bethesda	Bethesda	NNP
cord-010499-yefxrj30	258	3	Research	Research	NNP
cord-010499-yefxrj30	258	4	Labs	Labs	NNP
cord-010499-yefxrj30	258	5	)	)	-RRB-
cord-010499-yefxrj30	258	6	at	at	IN
cord-010499-yefxrj30	258	7	their	-PRON-	PRP$
cord-010499-yefxrj30	258	8	single	single	JJ
cord-010499-yefxrj30	258	9	sites	site	NNS
cord-010499-yefxrj30	258	10	within	within	IN
cord-010499-yefxrj30	258	11	the	the	DT
cord-010499-yefxrj30	258	12	pUC9	pUC9	NNP
cord-010499-yefxrj30	258	13	polylinker	polylinker	NN
cord-010499-yefxrj30	258	14	.	.	.
cord-010499-yefxrj30	259	1	About	about	IN
cord-010499-yefxrj30	259	2	lOOng	lOOng	NNP
cord-010499-yefxrj30	259	3	of	of	IN
cord-010499-yefxrj30	259	4	the	the	DT
cord-010499-yefxrj30	259	5	prepared	prepared	JJ
cord-010499-yefxrj30	259	6	vector	vector	NN
cord-010499-yefxrj30	259	7	was	be	VBD
cord-010499-yefxrj30	259	8	used	use	VBN
cord-010499-yefxrj30	259	9	without	without	IN
cord-010499-yefxrj30	259	10	purification	purification	NN
cord-010499-yefxrj30	259	11	in	in	IN
cord-010499-yefxrj30	259	12	a	a	DT
cord-010499-yefxrj30	259	13	20	20	CD
cord-010499-yefxrj30	259	14	nl	nl	NNP
cord-010499-yefxrj30	259	15	ligation	ligation	NN
cord-010499-yefxrj30	259	16	containing	contain	VBG
cord-010499-yefxrj30	259	17	a	a	DT
cord-010499-yefxrj30	259	18	10-fold	10-fold	JJ
cord-010499-yefxrj30	259	19	molar	molar	JJ
cord-010499-yefxrj30	259	20	excess	excess	NN
cord-010499-yefxrj30	259	21	of	of	IN
cord-010499-yefxrj30	259	22	paired	pair	VBN
cord-010499-yefxrj30	259	23	complementary	complementary	JJ
cord-010499-yefxrj30	259	24	oligonucleotide	oligonucleotide	NN
cord-010499-yefxrj30	259	25	primers	primer	NNS
cord-010499-yefxrj30	259	26	,	,	,
cord-010499-yefxrj30	259	27	kindly	kindly	RB
cord-010499-yefxrj30	259	28	prepared	prepare	VBN
cord-010499-yefxrj30	259	29	by	by	IN
cord-010499-yefxrj30	259	30	Yim	Yim	NNP
cord-010499-yefxrj30	259	31	Foon	Foon	NNP
cord-010499-yefxrj30	259	32	Lee	Lee	NNP
cord-010499-yefxrj30	259	33	(	(	-LRB-
cord-010499-yefxrj30	259	34	Howard	Howard	NNP
cord-010499-yefxrj30	259	35	Hughes	Hughes	NNP
cord-010499-yefxrj30	259	36	Institute	Institute	NNP
cord-010499-yefxrj30	259	37	,	,	,
cord-010499-yefxrj30	259	38	University	University	NNP
cord-010499-yefxrj30	259	39	of	of	IN
cord-010499-yefxrj30	259	40	Washington	Washington	NNP
cord-010499-yefxrj30	259	41	)	)	-RRB-
cord-010499-yefxrj30	259	42	on	on	IN
cord-010499-yefxrj30	259	43	an	an	DT
cord-010499-yefxrj30	259	44	Applied	Applied	NNP
cord-010499-yefxrj30	259	45	Biosystems	Biosystems	NNP
cord-010499-yefxrj30	259	46	380B	380b	CD
cord-010499-yefxrj30	259	47	synthesizer	synthesizer	NN
cord-010499-yefxrj30	259	48	.	.	.
cord-010499-yefxrj30	260	1	Ligations	ligation	NNS
cord-010499-yefxrj30	260	2	were	be	VBD
cord-010499-yefxrj30	260	3	carried	carry	VBN
cord-010499-yefxrj30	260	4	out	out	RP
cord-010499-yefxrj30	260	5	at	at	IN
cord-010499-yefxrj30	260	6	room	room	NN
cord-010499-yefxrj30	260	7	temperature	temperature	NN
cord-010499-yefxrj30	260	8	for	for	IN
cord-010499-yefxrj30	260	9	3	3	CD
cord-010499-yefxrj30	260	10	-	-	SYM
cord-010499-yefxrj30	260	11	12	12	CD
cord-010499-yefxrj30	260	12	h.	h.	NN
cord-010499-yefxrj30	260	13	then	then	RB
cord-010499-yefxrj30	260	14	transformed	transform	VBD
cord-010499-yefxrj30	260	15	into	into	IN
cord-010499-yefxrj30	260	16	a	a	DT
cord-010499-yefxrj30	260	17	lac~	lac~	CD
cord-010499-yefxrj30	260	18	strain	strain	NN
cord-010499-yefxrj30	260	19	for	for	IN
cord-010499-yefxrj30	260	20	screening	screening	NN
cord-010499-yefxrj30	260	21	on	on	IN
cord-010499-yefxrj30	260	22	Xgal	Xgal	NNP
cord-010499-yefxrj30	260	23	indicator	indicator	NN
cord-010499-yefxrj30	260	24	plates	plate	NNS
cord-010499-yefxrj30	260	25	.	.	.
cord-010499-yefxrj30	261	1	Plasmid	Plasmid	NNP
cord-010499-yefxrj30	261	2	DNA	DNA	NNP
cord-010499-yefxrj30	261	3	from	from	IN
cord-010499-yefxrj30	261	4	(	(	-LRB-
cord-010499-yefxrj30	261	5	leaky	leaky	JJ
cord-010499-yefxrj30	261	6	)	)	-RRB-
cord-010499-yefxrj30	261	7	lac	lac	NNP
cord-010499-yefxrj30	261	8	candidates	candidate	NNS
cord-010499-yefxrj30	261	9	was	be	VBD
cord-010499-yefxrj30	261	10	examined	examine	VBN
cord-010499-yefxrj30	261	11	by	by	IN
cord-010499-yefxrj30	261	12	restriction	restriction	NN
cord-010499-yefxrj30	261	13	analysis	analysis	NN
cord-010499-yefxrj30	261	14	and	and	CC
cord-010499-yefxrj30	261	15	by	by	IN
cord-010499-yefxrj30	261	16	DNA	dna	NN
cord-010499-yefxrj30	261	17	sequencing	sequencing	NN
cord-010499-yefxrj30	261	18	of	of	IN
cord-010499-yefxrj30	261	19	the	the	DT
cord-010499-yefxrj30	261	20	salient	salient	JJ
cord-010499-yefxrj30	261	21	region	region	NN
cord-010499-yefxrj30	261	22	of	of	IN
cord-010499-yefxrj30	261	23	the	the	DT
cord-010499-yefxrj30	261	24	lacZ	lacZ	NNP
cord-010499-yefxrj30	261	25	gene	gene	NN
cord-010499-yefxrj30	261	26	.	.	.
cord-010499-yefxrj30	262	1	Sequences	sequence	NNS
cord-010499-yefxrj30	262	2	of	of	IN
cord-010499-yefxrj30	262	3	the	the	DT
cord-010499-yefxrj30	262	4	oligonucleotide	oligonucleotide	JJ
cord-010499-yefxrj30	262	5	pairs	pair	NNS
cord-010499-yefxrj30	262	6	were	be	VBD
cord-010499-yefxrj30	262	7	:	:	:
cord-010499-yefxrj30	262	8	HIV13	HIV13	NNP
cord-010499-yefxrj30	262	9	/	/	SYM
cord-010499-yefxrj30	262	10	HIV13-A3	HIV13-A3	NNP
cord-010499-yefxrj30	262	11	,	,	,
cord-010499-yefxrj30	262	12	5'-AGCTCTAATT^TTTAGG	5'-agctctaatt^tttagg	CD
cord-010499-yefxrj30	262	13	-	-	HYPH
cord-010499-yefxrj30	262	14	GA-3	ga-3	NN
cord-010499-yefxrj30	262	15	;	;	:
cord-010499-yefxrj30	262	16	and	and	CC
cord-010499-yefxrj30	262	17	5'-GATCTCCCTAAAIAATTAG-3	5'-gatctccctaaaiaattag-3	CD
cord-010499-yefxrj30	262	18	'	'	''
cord-010499-yefxrj30	262	19	;	;	:
cord-010499-yefxrj30	262	20	H1V201	h1v201	UH
cord-010499-yefxrj30	262	21	,	,	,
cord-010499-yefxrj30	262	22	5-AGCTCTAAI	5-agctctaai	CD
cord-010499-yefxrj30	262	23	1	1	CD
cord-010499-yefxrj30	263	1	I	-PRON-	PRP
cord-010499-yefxrj30	264	1	I	-PRON-	PRP
cord-010499-yefxrj30	265	1	I	-PRON-	PRP
cord-010499-yefxrj30	265	2	IAGGGAAGG-3	IAGGGAAGG-3	NNP
cord-010499-yefxrj30	265	3	'	'	''
cord-010499-yefxrj30	265	4	and	and	CC
cord-010499-yefxrj30	265	5	5-GATCCCTTCC	5-gatcccttcc	CD
cord-010499-yefxrj30	265	6	-	-	HYPH
cord-010499-yefxrj30	265	7	CTAAAAAATTAG-3	CTAAAAAATTAG-3	NNP
cord-010499-yefxrj30	265	8	'	'	''
cord-010499-yefxrj30	265	9	;	;	:
cord-010499-yefxrj30	265	10	HIV201-U7	HIV201-U7	NNP
cord-010499-yefxrj30	265	11	,	,	,
cord-010499-yefxrj30	266	1	5'-AGCTCTAAl	5'-agctctaal	CD
cord-010499-yefxrj30	266	2	1	1	CD
cord-010499-yefxrj30	267	1	I	-PRON-	PRP
cord-010499-yefxrj30	268	1	I	-PRON-	PRP
cord-010499-yefxrj30	269	1	I	-PRON-	PRP
cord-010499-yefxrj30	270	1	I	-PRON-	PRP
cord-010499-yefxrj30	270	2	I	I	NNP
cord-010499-yefxrj30	270	3	-	-	HYPH
cord-010499-yefxrj30	270	4	GGGAAGG-3	GGGAAGG-3	NNP
cord-010499-yefxrj30	270	5	'	'	POS
cord-010499-yefxrj30	270	6	and	and	CC
cord-010499-yefxrj30	270	7	5'-GATCCCTTCCCAAAAAAATTAG-3	5'-gatcccttcccaaaaaaattag-3	CD
cord-010499-yefxrj30	270	8	'	'	''
cord-010499-yefxrj30	270	9	.	.	.
cord-010499-yefxrj30	271	1	Bacterial	bacterial	JJ
cord-010499-yefxrj30	271	2	strains	strain	NNS
cord-010499-yefxrj30	271	3	and	and	CC
cord-010499-yefxrj30	271	4	culture	culture	NN
cord-010499-yefxrj30	271	5	conditions	condition	NNS
cord-010499-yefxrj30	271	6	were	be	VBD
cord-010499-yefxrj30	271	7	as	as	IN
cord-010499-yefxrj30	271	8	described	describe	VBN
cord-010499-yefxrj30	271	9	previously	previously	RB
cord-010499-yefxrj30	271	10	(	(	-LRB-
cord-010499-yefxrj30	271	11	Weiss	Weiss	NNP
cord-010499-yefxrj30	271	12	etai	etai	NNP
cord-010499-yefxrj30	271	13	.	.	NNP
cord-010499-yefxrj30	271	14	,	,	,
cord-010499-yefxrj30	271	15	1988	1988	CD
cord-010499-yefxrj30	271	16	)	)	-RRB-
cord-010499-yefxrj30	271	17	,	,	,
cord-010499-yefxrj30	271	18	except	except	IN
cord-010499-yefxrj30	271	19	that	that	DT
cord-010499-yefxrj30	271	20	minimal	minimal	JJ
cord-010499-yefxrj30	271	21	glucose	glucose	NN
cord-010499-yefxrj30	271	22	-	-	:
cord-010499-yefxrj30	271	23	M63	M63	NNP
cord-010499-yefxrj30	271	24	medium	medium	NN
cord-010499-yefxrj30	271	25	was	be	VBD
cord-010499-yefxrj30	271	26	supplemented	supplement	VBN
cord-010499-yefxrj30	271	27	only	only	RB
cord-010499-yefxrj30	271	28	with	with	IN
cord-010499-yefxrj30	271	29	isoleucine	isoleucine	NN
cord-010499-yefxrj30	271	30	and	and	CC
cord-010499-yefxrj30	271	31	valine	valine	NN
cord-010499-yefxrj30	271	32	in	in	IN
cord-010499-yefxrj30	271	33	addition	addition	NN
cord-010499-yefxrj30	271	34	to	to	IN
cord-010499-yefxrj30	271	35	the	the	DT
cord-010499-yefxrj30	271	36	strains	strain	NNS
cord-010499-yefxrj30	271	37	'	'	POS
cord-010499-yefxrj30	271	38	growth	growth	NN
cord-010499-yefxrj30	271	39	requirements	requirement	NNS
cord-010499-yefxrj30	271	40	.	.	.
cord-010499-yefxrj30	272	1	The	the	DT
cord-010499-yefxrj30	272	2	lacZ	lacZ	NNP
cord-010499-yefxrj30	272	3	plasmids	plasmid	NNS
cord-010499-yefxrj30	272	4	were	be	VBD
cord-010499-yefxrj30	272	5	kept	keep	VBN
cord-010499-yefxrj30	272	6	under	under	IN
cord-010499-yefxrj30	272	7	selection	selection	NN
cord-010499-yefxrj30	272	8	through	through	IN
cord-010499-yefxrj30	272	9	the	the	DT
cord-010499-yefxrj30	272	10	presence	presence	NN
cord-010499-yefxrj30	272	11	of	of	IN
cord-010499-yefxrj30	272	12	1mgml	1mgml	CD
cord-010499-yefxrj30	272	13	^	^	.
cord-010499-yefxrj30	272	14	carbenicillin	carbenicillin	NNP
cord-010499-yefxrj30	272	15	.	.	.
cord-010499-yefxrj30	273	1	tn	tn	NNP
cord-010499-yefxrj30	273	2	most	most	JJS
cord-010499-yefxrj30	273	3	experiments	experiment	NNS
cord-010499-yefxrj30	273	4	.	.	.
cord-010499-yefxrj30	274	1	the	the	DT
cord-010499-yefxrj30	274	2	host	host	NN
cord-010499-yefxrj30	274	3	cells	cell	NNS
cord-010499-yefxrj30	274	4	also	also	RB
cord-010499-yefxrj30	274	5	carried	carry	VBD
cord-010499-yefxrj30	274	6	pPYIOII	pPYIOII	NNP
cord-010499-yefxrj30	274	7	,	,	,
cord-010499-yefxrj30	274	8	a	a	DT
cord-010499-yefxrj30	274	9	compatible	compatible	JJ
cord-010499-yefxrj30	274	10	plasmid	plasmid	NN
cord-010499-yefxrj30	274	11	(	(	-LRB-
cord-010499-yefxrj30	274	12	spectinomycin	spectinomycin	NNS
cord-010499-yefxrj30	274	13	resistant	resistant	JJ
cord-010499-yefxrj30	274	14	,	,	,
cord-010499-yefxrj30	274	15	streptomycin	streptomycin	NN
cord-010499-yefxrj30	274	16	resistant	resistant	JJ
cord-010499-yefxrj30	274	17	)	)	-RRB-
cord-010499-yefxrj30	274	18	carrying	carry	VBG
cord-010499-yefxrj30	274	19	a	a	DT
cord-010499-yefxrj30	274	20	complete	complete	JJ
cord-010499-yefxrj30	274	21	lacl'^	lacl'^	NN
cord-010499-yefxrj30	274	22	gene	gene	NN
cord-010499-yefxrj30	274	23	.	.	.
cord-010499-yefxrj30	275	1	Selection	selection	NN
cord-010499-yefxrj30	275	2	for	for	IN
cord-010499-yefxrj30	275	3	this	this	DT
cord-010499-yefxrj30	275	4	plasmid	plasmid	NN
cord-010499-yefxrj30	275	5	was	be	VBD
cord-010499-yefxrj30	275	6	maintained	maintain	VBN
cord-010499-yefxrj30	275	7	through	through	IN
cord-010499-yefxrj30	275	8	the	the	DT
cord-010499-yefxrj30	275	9	presence	presence	NN
cord-010499-yefxrj30	275	10	of	of	IN
cord-010499-yefxrj30	275	11	50|igmr	50|igmr	NNP
cord-010499-yefxrj30	275	12	'	'	POS
cord-010499-yefxrj30	275	13	'	'	''
cord-010499-yefxrj30	275	14	spectinomycin	spectinomycin	NNS
cord-010499-yefxrj30	275	15	in	in	IN
cord-010499-yefxrj30	275	16	the	the	DT
cord-010499-yefxrj30	275	17	overnight	overnight	JJ
cord-010499-yefxrj30	275	18	cultures	culture	NNS
cord-010499-yefxrj30	275	19	used	use	VBN
cord-010499-yefxrj30	275	20	to	to	TO
cord-010499-yefxrj30	275	21	inoculate	inoculate	VB
cord-010499-yefxrj30	275	22	our	-PRON-	PRP$
cord-010499-yefxrj30	275	23	experimental	experimental	JJ
cord-010499-yefxrj30	275	24	cultures	culture	NNS
cord-010499-yefxrj30	275	25	,	,	,
cord-010499-yefxrj30	275	26	but	but	CC
cord-010499-yefxrj30	275	27	spectinomycin	spectinomycin	NNS
cord-010499-yefxrj30	275	28	was	be	VBD
cord-010499-yefxrj30	275	29	not	not	RB
cord-010499-yefxrj30	275	30	present	present	JJ
cord-010499-yefxrj30	275	31	during	during	IN
cord-010499-yefxrj30	275	32	induction	induction	NN
cord-010499-yefxrj30	275	33	of	of	IN
cord-010499-yefxrj30	275	34	lacZ.	lacZ.	NNP
cord-010499-yefxrj30	275	35	Cell	cell	NN
cord-010499-yefxrj30	275	36	-	-	HYPH
cord-010499-yefxrj30	275	37	free	free	JJ
cord-010499-yefxrj30	275	38	extracts	extract	NNS
cord-010499-yefxrj30	275	39	were	be	VBD
cord-010499-yefxrj30	275	40	made	make	VBN
cord-010499-yefxrj30	275	41	by	by	IN
cord-010499-yefxrj30	275	42	resuspending	resuspend	VBG
cord-010499-yefxrj30	275	43	cells	cell	NNS
cord-010499-yefxrj30	275	44	at	at	IN
cord-010499-yefxrj30	275	45	a	a	DT
cord-010499-yefxrj30	275	46	final	final	JJ
cord-010499-yefxrj30	275	47	protein	protein	NN
cord-010499-yefxrj30	275	48	concentration	concentration	NN
cord-010499-yefxrj30	275	49	of	of	IN
cord-010499-yefxrj30	275	50	1	1	CD
cord-010499-yefxrj30	275	51	-2	-2	NNP
cord-010499-yefxrj30	275	52	mg	mg	NNP
cord-010499-yefxrj30	275	53	ml	ml	NN
cord-010499-yefxrj30	275	54	"	"	``
cord-010499-yefxrj30	275	55	\	\	NN
cord-010499-yefxrj30	275	56	and	and	CC
cord-010499-yefxrj30	275	57	sonicating	sonicate	VBG
cord-010499-yefxrj30	275	58	for	for	IN
cord-010499-yefxrj30	275	59	20	20	CD
cord-010499-yefxrj30	275	60	s	s	NN
cord-010499-yefxrj30	275	61	at	at	IN
cord-010499-yefxrj30	275	62	ice	ice	NN
cord-010499-yefxrj30	275	63	-	-	HYPH
cord-010499-yefxrj30	275	64	water	water	NN
cord-010499-yefxrj30	275	65	temperature	temperature	NN
cord-010499-yefxrj30	275	66	in	in	IN
cord-010499-yefxrj30	275	67	a	a	DT
cord-010499-yefxrj30	275	68	Braunsonic	Braunsonic	NNP
cord-010499-yefxrj30	275	69	1510	1510	CD
cord-010499-yefxrj30	275	70	instrument	instrument	NN
cord-010499-yefxrj30	275	71	;	;	:
cord-010499-yefxrj30	275	72	cell	cell	NN
cord-010499-yefxrj30	275	73	debris	debris	NN
cord-010499-yefxrj30	275	74	was	be	VBD
cord-010499-yefxrj30	275	75	centriiuged	centriiuge	VBN
cord-010499-yefxrj30	275	76	out	out	RP
cord-010499-yefxrj30	275	77	at	at	IN
cord-010499-yefxrj30	275	78	26000	26000	CD
cord-010499-yefxrj30	275	79	x	x	SYM
cord-010499-yefxrj30	275	80	g	g	NN
cord-010499-yefxrj30	275	81	in	in	IN
cord-010499-yefxrj30	275	82	a	a	DT
cord-010499-yefxrj30	275	83	Sorvaii	Sorvaii	NNP
cord-010499-yefxrj30	275	84	refrigerated	refrigerate	VBN
cord-010499-yefxrj30	275	85	centrifuge	centrifuge	NN
cord-010499-yefxrj30	275	86	.	.	.
cord-010499-yefxrj30	276	1	Beta	beta	JJ
cord-010499-yefxrj30	276	2	-	-	HYPH
cord-010499-yefxrj30	276	3	galactosidase	galactosidase	NN
cord-010499-yefxrj30	276	4	activity	activity	NN
cord-010499-yefxrj30	276	5	was	be	VBD
cord-010499-yefxrj30	276	6	measured	measure	VBN
cord-010499-yefxrj30	276	7	by	by	IN
cord-010499-yefxrj30	276	8	incubating	incubate	VBG
cord-010499-yefxrj30	276	9	up	up	IN
cord-010499-yefxrj30	276	10	to	to	TO
cord-010499-yefxrj30	276	11	50	50	CD
cord-010499-yefxrj30	276	12	MI	MI	NNS
cord-010499-yefxrj30	276	13	of	of	IN
cord-010499-yefxrj30	276	14	extract	extract	NN
cord-010499-yefxrj30	276	15	with	with	IN
cord-010499-yefxrj30	276	16	250	250	CD
cord-010499-yefxrj30	276	17	iil	iil	NNP
cord-010499-yefxrj30	276	18	ONPG	ONPG	NNP
cord-010499-yefxrj30	276	19	(	(	-LRB-
cord-010499-yefxrj30	276	20	0.8mgml	0.8mgml	:
cord-010499-yefxrj30	276	21	'	'	''
cord-010499-yefxrj30	276	22	in	in	IN
cord-010499-yefxrj30	276	23	50	50	CD
cord-010499-yefxrj30	276	24	mM	mm	CD
cord-010499-yefxrj30	276	25	sodium	sodium	NN
cord-010499-yefxrj30	276	26	phosphate	phosphate	NN
cord-010499-yefxrj30	276	27	buffer	buffer	NN
cord-010499-yefxrj30	276	28	.	.	.
cord-010499-yefxrj30	277	1	pH	pH	NNP
cord-010499-yefxrj30	277	2	7.0	7.0	CD
cord-010499-yefxrj30	277	3	)	)	-RRB-
cord-010499-yefxrj30	277	4	at	at	IN
cord-010499-yefxrj30	277	5	room	room	NN
cord-010499-yefxrj30	277	6	temperature	temperature	NN
cord-010499-yefxrj30	277	7	,	,	,
cord-010499-yefxrj30	277	8	and	and	CC
cord-010499-yefxrj30	277	9	monitoring	monitor	VBG
cord-010499-yefxrj30	277	10	the	the	DT
cord-010499-yefxrj30	277	11	accumulation	accumulation	NN
cord-010499-yefxrj30	277	12	of	of	IN
cord-010499-yefxrj30	277	13	o	o	NN
cord-010499-yefxrj30	277	14	-	-	HYPH
cord-010499-yefxrj30	277	15	nitrophenol	nitrophenol	NN
cord-010499-yefxrj30	277	16	at	at	IN
cord-010499-yefxrj30	277	17	A420	A420	NNP
cord-010499-yefxrj30	277	18	using	use	VBG
cord-010499-yefxrj30	277	19	a	a	DT
cord-010499-yefxrj30	277	20	continuously	continuously	RB
cord-010499-yefxrj30	277	21	recording	record	VBG
cord-010499-yefxrj30	277	22	Gilford	Gilford	NNP
cord-010499-yefxrj30	277	23	2400	2400	CD
cord-010499-yefxrj30	277	24	-	-	SYM
cord-010499-yefxrj30	277	25	2	2	CD
cord-010499-yefxrj30	277	26	spectrophotomer	spectrophotomer	NN
cord-010499-yefxrj30	277	27	.	.	.
cord-010499-yefxrj30	278	1	One	one	CD
cord-010499-yefxrj30	278	2	enzyme	enzyme	NN
cord-010499-yefxrj30	278	3	unit	unit	NN
cord-010499-yefxrj30	278	4	is	be	VBZ
cord-010499-yefxrj30	278	5	defined	define	VBN
cord-010499-yefxrj30	278	6	as	as	IN
cord-010499-yefxrj30	278	7	the	the	DT
cord-010499-yefxrj30	278	8	amount	amount	NN
cord-010499-yefxrj30	278	9	of	of	IN
cord-010499-yefxrj30	278	10	enzyme	enzyme	NN
cord-010499-yefxrj30	278	11	required	require	VBN
cord-010499-yefxrj30	278	12	to	to	TO
cord-010499-yefxrj30	278	13	produce	produce	VB
cord-010499-yefxrj30	278	14	a	a	DT
cord-010499-yefxrj30	278	15	change	change	NN
cord-010499-yefxrj30	278	16	in	in	IN
cord-010499-yefxrj30	278	17	absorbance	absorbance	NN
cord-010499-yefxrj30	278	18	of	of	IN
cord-010499-yefxrj30	278	19	one	one	CD
cord-010499-yefxrj30	278	20	per	per	IN
cord-010499-yefxrj30	278	21	minute	minute	NN
cord-010499-yefxrj30	278	22	.	.	.
cord-010499-yefxrj30	279	1	Protein	protein	NN
cord-010499-yefxrj30	279	2	concentrations	concentration	NNS
cord-010499-yefxrj30	279	3	were	be	VBD
cord-010499-yefxrj30	279	4	determined	determine	VBN
cord-010499-yefxrj30	279	5	by	by	IN
cord-010499-yefxrj30	279	6	the	the	DT
cord-010499-yefxrj30	279	7	method	method	NN
cord-010499-yefxrj30	279	8	of	of	IN
cord-010499-yefxrj30	279	9	Lowry	Lowry	NNP
cord-010499-yefxrj30	279	10	et	et	NNP
cord-010499-yefxrj30	279	11	al	al	NNP
cord-010499-yefxrj30	279	12	.	.	.
cord-010499-yefxrj30	280	1	(	(	-LRB-
cord-010499-yefxrj30	280	2	1951	1951	CD
cord-010499-yefxrj30	280	3	)	)	-RRB-
cord-010499-yefxrj30	280	4	using	use	VBG
cord-010499-yefxrj30	280	5	egg	egg	NN
cord-010499-yefxrj30	280	6	albumin	albumin	NN
cord-010499-yefxrj30	280	7	as	as	IN
cord-010499-yefxrj30	280	8	a	a	DT
cord-010499-yefxrj30	280	9	protein	protein	NN
cord-010499-yefxrj30	280	10	standard	standard	NN
cord-010499-yefxrj30	280	11	.	.	.
cord-010499-yefxrj30	281	1	Differential	differential	JJ
cord-010499-yefxrj30	281	2	rates	rate	NNS
cord-010499-yefxrj30	281	3	in	in	IN
cord-010499-yefxrj30	281	4	enzyme	enzyme	NN
cord-010499-yefxrj30	281	5	units	unit	NNS
cord-010499-yefxrj30	281	6	per	per	IN
cord-010499-yefxrj30	281	7	mg	mg	NN
cord-010499-yefxrj30	281	8	of	of	IN
cord-010499-yefxrj30	281	9	protein	protein	NN
cord-010499-yefxrj30	281	10	were	be	VBD
cord-010499-yefxrj30	281	11	computed	compute	VBN
cord-010499-yefxrj30	281	12	for	for	IN
cord-010499-yefxrj30	281	13	the	the	DT
cord-010499-yefxrj30	281	14	period	period	NN
cord-010499-yefxrj30	281	15	of	of	IN
cord-010499-yefxrj30	281	16	Induction	Induction	NNP
cord-010499-yefxrj30	281	17	(	(	-LRB-
cord-010499-yefxrj30	281	18	approximately	approximately	RB
cord-010499-yefxrj30	281	19	one	one	CD
cord-010499-yefxrj30	281	20	doubling	double	VBG
cord-010499-yefxrj30	281	21	in	in	IN
cord-010499-yefxrj30	281	22	2mM	2mm	CD
cord-010499-yefxrj30	281	23	IPTG	IPTG	NNP
cord-010499-yefxrj30	281	24	,	,	,
cord-010499-yefxrj30	281	25	2.5	2.5	CD
cord-010499-yefxrj30	281	26	mM	mm	CD
cord-010499-yefxrj30	281	27	cAMP	camp	NN
cord-010499-yefxrj30	281	28	)	)	-RRB-
cord-010499-yefxrj30	281	29	with	with	IN
cord-010499-yefxrj30	281	30	or	or	CC
cord-010499-yefxrj30	281	31	without	without	IN
cord-010499-yefxrj30	281	32	growth	growth	NN
cord-010499-yefxrj30	281	33	limitation	limitation	NN
cord-010499-yefxrj30	281	34	(	(	-LRB-
cord-010499-yefxrj30	281	35	as	as	IN
cord-010499-yefxrj30	281	36	indicated	indicate	VBN
cord-010499-yefxrj30	281	37	)	)	-RRB-
cord-010499-yefxrj30	281	38	.	.	.
cord-010499-yefxrj30	282	1	Purification	purification	NN
cord-010499-yefxrj30	282	2	of	of	IN
cord-010499-yefxrj30	282	3	0-galactosidase	0-galactosidase	CD
cord-010499-yefxrj30	282	4	by	by	IN
cord-010499-yefxrj30	282	5	immunoprecipitation	immunoprecipitation	NN
cord-010499-yefxrj30	282	6	with	with	IN
cord-010499-yefxrj30	282	7	specific	specific	JJ
cord-010499-yefxrj30	282	8	antiserum	antiserum	NN
cord-010499-yefxrj30	282	9	was	be	VBD
cord-010499-yefxrj30	282	10	as	as	IN
cord-010499-yefxrj30	282	11	described	describe	VBN
cord-010499-yefxrj30	282	12	in	in	IN
cord-010499-yefxrj30	282	13	Gallant	Gallant	NNP
cord-010499-yefxrj30	282	14	and	and	CC
cord-010499-yefxrj30	282	15	Lindsiey	Lindsiey	NNP
cord-010499-yefxrj30	282	16	(	(	-LRB-
cord-010499-yefxrj30	282	17	1992	1992	CD
cord-010499-yefxrj30	282	18	)	)	-RRB-
cord-010499-yefxrj30	282	19	.	.	.
cord-010499-yefxrj30	283	1	N	n	CD
cord-010499-yefxrj30	283	2	-	-	HYPH
cord-010499-yefxrj30	283	3	terminal	terminal	NN
cord-010499-yefxrj30	283	4	amino	amino	NN
cord-010499-yefxrj30	283	5	acid	acid	NN
cord-010499-yefxrj30	283	6	analysis	analysis	NN
cord-010499-yefxrj30	283	7	of	of	IN
cord-010499-yefxrj30	283	8	the	the	DT
cord-010499-yefxrj30	283	9	purified	purify	VBN
cord-010499-yefxrj30	283	10	protein	protein	NN
cord-010499-yefxrj30	283	11	was	be	VBD
cord-010499-yefxrj30	283	12	performed	perform	VBN
cord-010499-yefxrj30	283	13	by	by	IN
cord-010499-yefxrj30	283	14	automated	automate	VBN
cord-010499-yefxrj30	283	15	Edman	Edman	NNP
cord-010499-yefxrj30	283	16	degradation	degradation	NN
cord-010499-yefxrj30	283	17	on	on	IN
cord-010499-yefxrj30	283	18	Applied	Applied	NNP
cord-010499-yefxrj30	283	19	Biosystems	Biosystems	NNP
cord-010499-yefxrj30	283	20	477	477	CD
cord-010499-yefxrj30	284	1	A	a	DT
cord-010499-yefxrj30	284	2	pulsed	pulse	VBN
cord-010499-yefxrj30	284	3	-	-	HYPH
cord-010499-yefxrj30	284	4	liquid	liquid	NN
cord-010499-yefxrj30	284	5	phase	phase	NN
cord-010499-yefxrj30	284	6	sequencer	sequencer	NN
cord-010499-yefxrj30	284	7	and	and	CC
cord-010499-yefxrj30	284	8	470	470	CD
cord-010499-yefxrj30	284	9	A	a	DT
cord-010499-yefxrj30	284	10	gas	gas	NN
cord-010499-yefxrj30	284	11	phase	phase	NN
cord-010499-yefxrj30	284	12	sequencer	sequencer	NN
cord-010499-yefxrj30	284	13	at	at	IN
cord-010499-yefxrj30	284	14	University	University	NNP
cord-010499-yefxrj30	284	15	of	of	IN
cord-010499-yefxrj30	284	16	Illinois	Illinois	NNP
cord-010499-yefxrj30	284	17	Biotechnology	Biotechnology	NNP
cord-010499-yefxrj30	284	18	Center	Center	NNP
cord-010499-yefxrj30	284	19	and	and	CC
cord-010499-yefxrj30	284	20	University	University	NNP
cord-010499-yefxrj30	284	21	of	of	IN
cord-010499-yefxrj30	284	22	California	California	NNP
cord-010499-yefxrj30	284	23	,	,	,
cord-010499-yefxrj30	284	24	Riverside	Riverside	NNP
cord-010499-yefxrj30	284	25	.	.	.
cord-010499-yefxrj30	285	1	Data	datum	NNS
cord-010499-yefxrj30	285	2	were	be	VBD
cord-010499-yefxrj30	285	3	analysed	analyse	VBN
cord-010499-yefxrj30	285	4	using	use	VBG
cord-010499-yefxrj30	285	5	Applied	Applied	NNP
cord-010499-yefxrj30	285	6	Biosystems	Biosystems	NNP
cord-010499-yefxrj30	285	7	software	software	NN
cord-010499-yefxrj30	285	8	for	for	IN
cord-010499-yefxrj30	285	9	background	background	NN
cord-010499-yefxrj30	285	10	and	and	CC
cord-010499-yefxrj30	285	11	lag	lag	VB
cord-010499-yefxrj30	285	12	correction	correction	NN
cord-010499-yefxrj30	285	13	.	.	.
cord-010499-yefxrj30	286	1	Low	low	JJ
cord-010499-yefxrj30	286	2	activity	activity	NN
cord-010499-yefxrj30	286	3	of	of	IN
cord-010499-yefxrj30	286	4	p	p	NN
cord-010499-yefxrj30	286	5	-	-	HYPH
cord-010499-yefxrj30	286	6	galactosidase	galactosidase	NN
cord-010499-yefxrj30	286	7	in	in	IN
cord-010499-yefxrj30	286	8	frameshift	frameshift	NN
cord-010499-yefxrj30	286	9	mutants	mutant	NNS
cord-010499-yefxrj30	286	10	of	of	IN
cord-010499-yefxrj30	286	11	Escherichia	Escherichia	NNP
cord-010499-yefxrj30	286	12	coii	coii	VBD
cord-010499-yefxrj30	286	13	Normal	normal	JJ
cord-010499-yefxrj30	286	14	tRNAs	trna	NNS
cord-010499-yefxrj30	286	15	promote	promote	VBP
cord-010499-yefxrj30	286	16	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	286	17	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	286	18	Characterization	characterization	NN
cord-010499-yefxrj30	286	19	of	of	IN
cord-010499-yefxrj30	286	20	an	an	DT
cord-010499-yefxrj30	286	21	efficient	efficient	JJ
cord-010499-yefxrj30	286	22	coronavirus	coronavirus	NN
cord-010499-yefxrj30	286	23	ribosomal	ribosomal	NN
cord-010499-yefxrj30	286	24	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	286	25	signal	signal	NN
cord-010499-yefxrj30	286	26	:	:	:
cord-010499-yefxrj30	286	27	requirement	requirement	NN
cord-010499-yefxrj30	286	28	for	for	IN
cord-010499-yefxrj30	286	29	an	an	DT
cord-010499-yefxrj30	286	30	RNA	RNA	NNP
cord-010499-yefxrj30	286	31	pseudoknot	pseudoknot	NNP
cord-010499-yefxrj30	286	32	tRNA	tRNA	NNP
cord-010499-yefxrj30	286	33	anticodon	anticodon	NNP
cord-010499-yefxrj30	286	34	replacement	replacement	NN
cord-010499-yefxrj30	286	35	experiments	experiment	NNS
cord-010499-yefxrj30	286	36	show	show	VBP
cord-010499-yefxrj30	286	37	that	that	IN
cord-010499-yefxrj30	286	38	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	286	39	frameshifting	frameshifting	NN
cord-010499-yefxrj30	286	40	can	can	MD
cord-010499-yefxrj30	286	41	be	be	VB
cord-010499-yefxrj30	286	42	caused	cause	VBN
cord-010499-yefxrj30	286	43	by	by	IN
cord-010499-yefxrj30	286	44	doublet	doublet	NN
cord-010499-yefxrj30	286	45	decoding	decode	VBG
cord-010499-yefxrj30	286	46	Synthetic	synthetic	JJ
cord-010499-yefxrj30	286	47	a	a	DT
cord-010499-yefxrj30	286	48	-	-	HYPH
cord-010499-yefxrj30	286	49	amino	amino	NN
cord-010499-yefxrj30	286	50	-	-	HYPH
cord-010499-yefxrj30	286	51	phydroxycaproic	phydroxycaproic	NN
cord-010499-yefxrj30	286	52	acids	acid	NNS
cord-010499-yefxrj30	287	1	The	the	DT
cord-010499-yefxrj30	287	2	Stringent	stringent	JJ
cord-010499-yefxrj30	287	3	Response	response	NN
cord-010499-yefxrj30	288	1	How	how	WRB
cord-010499-yefxrj30	288	2	'	'	``
cord-010499-yefxrj30	288	3	hidden	hide	VBN
cord-010499-yefxrj30	288	4	'	'	''
cord-010499-yefxrj30	288	5	reading	reading	NN
cord-010499-yefxrj30	288	6	frames	frame	NNS
cord-010499-yefxrj30	288	7	are	be	VBP
cord-010499-yefxrj30	288	8	expressed	express	VBN
cord-010499-yefxrj30	288	9	Efficient	efficient	JJ
cord-010499-yefxrj30	288	10	translational	translational	JJ
cord-010499-yefxrj30	288	11	frameshifting	frameshifting	NN
cord-010499-yefxrj30	288	12	occurs	occur	VBZ
cord-010499-yefxrj30	288	13	within	within	IN
cord-010499-yefxrj30	288	14	a	a	DT
cord-010499-yefxrj30	288	15	conserved	conserved	JJ
cord-010499-yefxrj30	288	16	sequence	sequence	NN
cord-010499-yefxrj30	288	17	of	of	IN
cord-010499-yefxrj30	288	18	the	the	DT
cord-010499-yefxrj30	288	19	overlap	overlap	NN
cord-010499-yefxrj30	288	20	between	between	IN
cord-010499-yefxrj30	288	21	two	two	CD
cord-010499-yefxrj30	288	22	genes	gene	NNS
cord-010499-yefxrj30	288	23	of	of	IN
cord-010499-yefxrj30	288	24	a	a	DT
cord-010499-yefxrj30	288	25	yeast	yeast	NN
cord-010499-yefxrj30	288	26	Tyl	Tyl	NNP
cord-010499-yefxrj30	288	27	transposon	transposon	NN
cord-010499-yefxrj30	288	28	Translational	translational	JJ
cord-010499-yefxrj30	289	1	frameshifting	frameshifting	NNP
cord-010499-yefxrj30	290	1	:	:	:
cord-010499-yefxrj30	290	2	where	where	WRB
cord-010499-yefxrj30	290	3	will	will	MD
cord-010499-yefxrj30	290	4	it	-PRON-	PRP
cord-010499-yefxrj30	290	5	stop	stop	VB
cord-010499-yefxrj30	290	6	?	?	.
cord-010499-yefxrj30	291	1	Bacterial	bacterial	JJ
cord-010499-yefxrj30	291	2	peptide	peptide	NN
cord-010499-yefxrj30	291	3	chain	chain	NN
cord-010499-yefxrj30	291	4	release	release	NN
cord-010499-yefxrj30	291	5	factors	factor	NNS
cord-010499-yefxrj30	291	6	:	:	:
cord-010499-yefxrj30	291	7	conserved	conserved	JJ
cord-010499-yefxrj30	291	8	primary	primary	JJ
cord-010499-yefxrj30	291	9	structure	structure	NN
cord-010499-yefxrj30	291	10	and	and	CC
cord-010499-yefxrj30	291	11	possible	possible	JJ
cord-010499-yefxrj30	291	12	frameshift	frameshift	NN
cord-010499-yefxrj30	291	13	regulation	regulation	NN
cord-010499-yefxrj30	291	14	of	of	IN
cord-010499-yefxrj30	291	15	release	release	NN
cord-010499-yefxrj30	291	16	factor	factor	NN
cord-010499-yefxrj30	291	17	2	2	CD
cord-010499-yefxrj30	291	18	Use	Use	NNP
cord-010499-yefxrj30	291	19	of	of	IN
cord-010499-yefxrj30	291	20	tRNA	trna	NN
cord-010499-yefxrj30	291	21	suppressors	suppressor	NNS
cord-010499-yefxrj30	291	22	to	to	TO
cord-010499-yefxrj30	291	23	probe	probe	VB
cord-010499-yefxrj30	291	24	regulation	regulation	NN
cord-010499-yefxrj30	291	25	of	of	IN
cord-010499-yefxrj30	291	26	Escherichia	Escherichia	NNP
cord-010499-yefxrj30	291	27	coli	coli	NNS
cord-010499-yefxrj30	291	28	release	release	NN
cord-010499-yefxrj30	291	29	factor	factor	NN
cord-010499-yefxrj30	291	30	2	2	CD
cord-010499-yefxrj30	291	31	Mechanism	Mechanism	NNP
cord-010499-yefxrj30	291	32	of	of	IN
cord-010499-yefxrj30	291	33	the	the	DT
cord-010499-yefxrj30	291	34	rel	rel	NNP
cord-010499-yefxrj30	291	35	defect	defect	NN
cord-010499-yefxrj30	291	36	in	in	IN
cord-010499-yefxrj30	291	37	beta	beta	JJ
cord-010499-yefxrj30	291	38	-	-	HYPH
cord-010499-yefxrj30	291	39	galactosidase	galactosidase	NN
cord-010499-yefxrj30	291	40	synthesis	synthesis	NN
cord-010499-yefxrj30	292	1	Stringent	stringent	JJ
cord-010499-yefxrj30	292	2	Control	Control	NNP
cord-010499-yefxrj30	292	3	in	in	IN
cord-010499-yefxrj30	292	4	E.	E.	NNP
cord-010499-yefxrj30	292	5	coli	coli	NNS
cord-010499-yefxrj30	293	1	On	on	IN
cord-010499-yefxrj30	293	2	the	the	DT
cord-010499-yefxrj30	293	3	causes	cause	NNS
cord-010499-yefxrj30	293	4	and	and	CC
cord-010499-yefxrj30	293	5	prevention	prevention	NN
cord-010499-yefxrj30	293	6	of	of	IN
cord-010499-yefxrj30	293	7	mistranslation	mistranslation	NN
cord-010499-yefxrj30	293	8	Leftward	Leftward	NNP
cord-010499-yefxrj30	293	9	ribosome	ribosome	NN
cord-010499-yefxrj30	293	10	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	293	11	at	at	IN
cord-010499-yefxrj30	293	12	a	a	DT
cord-010499-yefxrj30	293	13	hungry	hungry	JJ
cord-010499-yefxrj30	293	14	codon	codon	NN
cord-010499-yefxrj30	294	1	Some	some	DT
cord-010499-yefxrj30	294	2	puzzle	puzzle	NN
cord-010499-yefxrj30	294	3	of	of	IN
cord-010499-yefxrj30	294	4	translational	translational	JJ
cord-010499-yefxrj30	294	5	accuracy	accuracy	NN
cord-010499-yefxrj30	294	6	Regulation	regulation	NN
cord-010499-yefxrj30	294	7	of	of	IN
cord-010499-yefxrj30	294	8	the	the	DT
cord-010499-yefxrj30	294	9	expression	expression	NN
cord-010499-yefxrj30	294	10	of	of	IN
cord-010499-yefxrj30	294	11	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	294	12	-	-	HYPH
cord-010499-yefxrj30	294	13	tRNA	trna	NN
cord-010499-yefxrj30	294	14	synthetases	synthetase	NNS
cord-010499-yefxrj30	294	15	and	and	CC
cord-010499-yefxrj30	294	16	translation	translation	NN
cord-010499-yefxrj30	294	17	factors	factor	NNS
cord-010499-yefxrj30	295	1	The	the	DT
cord-010499-yefxrj30	295	2	where	where	WRB
cord-010499-yefxrj30	295	3	,	,	,
cord-010499-yefxrj30	295	4	what	what	WP
cord-010499-yefxrj30	295	5	,	,	,
cord-010499-yefxrj30	295	6	and	and	CC
cord-010499-yefxrj30	295	7	how	how	WRB
cord-010499-yefxrj30	295	8	of	of	IN
cord-010499-yefxrj30	295	9	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	295	10	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	295	11	in	in	IN
cord-010499-yefxrj30	295	12	retroviral	retroviral	JJ
cord-010499-yefxrj30	295	13	protein	protein	NN
cord-010499-yefxrj30	295	14	synthesis	synthesis	NN
cord-010499-yefxrj30	295	15	Automated	automate	VBN
cord-010499-yefxrj30	295	16	amino	amino	NN
cord-010499-yefxrj30	295	17	acid	acid	NN
cord-010499-yefxrj30	295	18	sequence	sequence	NN
cord-010499-yefxrj30	295	19	assignment	assignment	NN
cord-010499-yefxrj30	295	20	:	:	:
cord-010499-yefxrj30	295	21	Development	development	NN
cord-010499-yefxrj30	295	22	of	of	IN
cord-010499-yefxrj30	295	23	a	a	DT
cord-010499-yefxrj30	295	24	fully	fully	RB
cord-010499-yefxrj30	295	25	automated	automate	VBN
cord-010499-yefxrj30	295	26	protein	protein	NN
cord-010499-yefxrj30	295	27	sequencer	sequencer	NN
cord-010499-yefxrj30	295	28	using	use	VBG
cord-010499-yefxrj30	295	29	edman	edman	NNP
cord-010499-yefxrj30	295	30	degradation	degradation	NN
cord-010499-yefxrj30	295	31	Signals	signal	NNS
cord-010499-yefxrj30	295	32	for	for	IN
cord-010499-yefxrj30	295	33	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	295	34	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	295	35	in	in	IN
cord-010499-yefxrj30	295	36	the	the	DT
cord-010499-yefxrj30	295	37	Rous	rous	JJ
cord-010499-yefxrj30	295	38	sarcoma	sarcoma	NN
cord-010499-yefxrj30	295	39	virus	virus	NN
cord-010499-yefxrj30	295	40	gag	gag	NN
cord-010499-yefxrj30	295	41	-	-	HYPH
cord-010499-yefxrj30	295	42	po	po	NN
cord-010499-yefxrj30	295	43	/	/	SYM
cord-010499-yefxrj30	295	44	region	region	NN
cord-010499-yefxrj30	296	1	Characterization	characterization	NN
cord-010499-yefxrj30	296	2	of	of	IN
cord-010499-yefxrj30	296	3	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	296	4	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	296	5	in	in	IN
cord-010499-yefxrj30	296	6	HIV-1	HIV-1	NNP
cord-010499-yefxrj30	296	7	gag	gag	NN
cord-010499-yefxrj30	296	8	-	-	HYPH
cord-010499-yefxrj30	296	9	poi	poi	NN
cord-010499-yefxrj30	296	10	expression	expression	NN
cord-010499-yefxrj30	296	11	On	on	IN
cord-010499-yefxrj30	296	12	the	the	DT
cord-010499-yefxrj30	296	13	role	role	NN
cord-010499-yefxrj30	296	14	of	of	IN
cord-010499-yefxrj30	296	15	the	the	DT
cord-010499-yefxrj30	296	16	P	p	NN
cord-010499-yefxrj30	296	17	-	-	HYPH
cord-010499-yefxrj30	296	18	site	site	NN
cord-010499-yefxrj30	296	19	in	in	IN
cord-010499-yefxrj30	296	20	leftward	leftward	JJ
cord-010499-yefxrj30	296	21	ribosome	ribosome	NN
cord-010499-yefxrj30	296	22	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	296	23	at	at	IN
cord-010499-yefxrj30	296	24	a	a	DT
cord-010499-yefxrj30	296	25	hungry	hungry	JJ
cord-010499-yefxrj30	296	26	codon	codon	NN
cord-010499-yefxrj30	297	1	The	the	DT
cord-010499-yefxrj30	297	2	secret	secret	JJ
cord-010499-yefxrj30	297	3	life	life	NN
cord-010499-yefxrj30	297	4	of	of	IN
cord-010499-yefxrj30	297	5	the	the	DT
cord-010499-yefxrj30	297	6	ribosome	ribosome	NN
cord-010499-yefxrj30	297	7	Transcription	Transcription	NNP
cord-010499-yefxrj30	297	8	Attenuation	Attenuation	NNP
cord-010499-yefxrj30	297	9	On	on	IN
cord-010499-yefxrj30	297	10	the	the	DT
cord-010499-yefxrj30	297	11	directional	directional	JJ
cord-010499-yefxrj30	297	12	specificity	specificity	NN
cord-010499-yefxrj30	297	13	of	of	IN
cord-010499-yefxrj30	297	14	ribosome	ribosome	NN
cord-010499-yefxrj30	297	15	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	297	16	at	at	IN
cord-010499-yefxrj30	297	17	a	a	DT
cord-010499-yefxrj30	297	18	hungry	hungry	JJ
cord-010499-yefxrj30	297	19	codon	codon	NN
cord-010499-yefxrj30	297	20	Protein	Protein	NNP
cord-010499-yefxrj30	297	21	measurement	measurement	NN
cord-010499-yefxrj30	297	22	with	with	IN
cord-010499-yefxrj30	297	23	the	the	DT
cord-010499-yefxrj30	297	24	Folin	Folin	NNP
cord-010499-yefxrj30	297	25	phenol	phenol	NN
cord-010499-yefxrj30	297	26	reagent	reagent	NN
cord-010499-yefxrj30	297	27	Signals	signal	NNS
cord-010499-yefxrj30	297	28	for	for	IN
cord-010499-yefxrj30	297	29	expression	expression	NN
cord-010499-yefxrj30	297	30	of	of	IN
cord-010499-yefxrj30	297	31	HIV	HIV	NNP
cord-010499-yefxrj30	297	32	pol	pol	NN
cord-010499-yefxrj30	297	33	gene	gene	NN
cord-010499-yefxrj30	297	34	by	by	IN
cord-010499-yefxrj30	297	35	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	297	36	frameshifting	frameshifting	NN
cord-010499-yefxrj30	297	37	.	.	.
cord-010499-yefxrj30	298	1	In	in	IN
cord-010499-yefxrj30	298	2	The	the	DT
cord-010499-yefxrj30	298	3	Control	Control	NNP
cord-010499-yefxrj30	298	4	of	of	IN
cord-010499-yefxrj30	298	5	Human	Human	NNP
cord-010499-yefxrj30	298	6	Retroviral	Retroviral	NNP
cord-010499-yefxrj30	298	7	Gene	Gene	NNP
cord-010499-yefxrj30	298	8	Expression	Expression	NNP
cord-010499-yefxrj30	298	9	Errors	Errors	NNPS
cord-010499-yefxrj30	298	10	and	and	CC
cord-010499-yefxrj30	298	11	alternatives	alternative	NNS
cord-010499-yefxrj30	298	12	in	in	IN
cord-010499-yefxrj30	298	13	reading	read	VBG
cord-010499-yefxrj30	298	14	the	the	DT
cord-010499-yefxrj30	298	15	universal	universal	JJ
cord-010499-yefxrj30	298	16	genetic	genetic	JJ
cord-010499-yefxrj30	298	17	code	code	NN
cord-010499-yefxrj30	298	18	Context	context	NN
cord-010499-yefxrj30	298	19	rules	rule	NNS
cord-010499-yefxrj30	298	20	of	of	IN
cord-010499-yefxrj30	298	21	rightward	rightward	JJ
cord-010499-yefxrj30	298	22	overiapping	overiapping	JJ
cord-010499-yefxrj30	298	23	reading	reading	NN
cord-010499-yefxrj30	298	24	In	in	IN
cord-010499-yefxrj30	298	25	vivo	vivo	NN
cord-010499-yefxrj30	298	26	role	role	NN
cord-010499-yefxrj30	298	27	of	of	IN
cord-010499-yefxrj30	298	28	the	the	DT
cord-010499-yefxrj30	298	29	relA	relA	NNS
cord-010499-yefxrj30	299	1	*	*	NFP
cord-010499-yefxrj30	299	2	gene	gene	NN
cord-010499-yefxrj30	299	3	in	in	IN
cord-010499-yefxrj30	299	4	the	the	DT
cord-010499-yefxrj30	299	5	regulation	regulation	NN
cord-010499-yefxrj30	299	6	of	of	IN
cord-010499-yefxrj30	299	7	the	the	DT
cord-010499-yefxrj30	299	8	/ac	/ac	CD
cord-010499-yefxrj30	299	9	operon	operon	NN
cord-010499-yefxrj30	299	10	Positive	positive	JJ
cord-010499-yefxrj30	299	11	control	control	NN
cord-010499-yefxrj30	299	12	of	of	IN
cord-010499-yefxrj30	299	13	lac	lac	NNP
cord-010499-yefxrj30	299	14	operon	operon	NN
cord-010499-yefxrj30	299	15	expression	expression	NN
cord-010499-yefxrj30	299	16	in	in	IN
cord-010499-yefxrj30	299	17	vitro	vitro	FW
cord-010499-yefxrj30	299	18	by	by	IN
cord-010499-yefxrj30	299	19	guanosine	guanosine	NN
cord-010499-yefxrj30	299	20	5'-diphosphate	5'-diphosphate	CD
cord-010499-yefxrj30	300	1	3'-diphosphate	3'-diphosphate	CD
cord-010499-yefxrj30	301	1	Complete	complete	JJ
cord-010499-yefxrj30	301	2	nucleotide	nucleotide	JJ
cord-010499-yefxrj30	301	3	sequence	sequence	NN
cord-010499-yefxrj30	301	4	of	of	IN
cord-010499-yefxrj30	301	5	the	the	DT
cord-010499-yefxrj30	301	6	AIDS	AIDS	NNP
cord-010499-yefxrj30	301	7	virus	virus	NN
cord-010499-yefxrj30	301	8	,	,	,
cord-010499-yefxrj30	301	9	HTLV	HTLV	NNP
cord-010499-yefxrj30	301	10	-	-	HYPH
cord-010499-yefxrj30	301	11	III	III	NNP
cord-010499-yefxrj30	302	1	The	the	DT
cord-010499-yefxrj30	302	2	pUC	pUC	NNP
cord-010499-yefxrj30	302	3	plasmids	plasmid	NNS
cord-010499-yefxrj30	302	4	,	,	,
cord-010499-yefxrj30	302	5	a	a	DT
cord-010499-yefxrj30	302	6	M13mp7	M13mp7	NNP
cord-010499-yefxrj30	302	7	derived	derive	VBN
cord-010499-yefxrj30	302	8	system	system	NN
cord-010499-yefxrj30	302	9	for	for	IN
cord-010499-yefxrj30	302	10	insertion	insertion	NN
cord-010499-yefxrj30	302	11	mutagenesis	mutagenesis	NN
cord-010499-yefxrj30	302	12	and	and	CC
cord-010499-yefxrj30	302	13	sequencing	sequence	VBG
cord-010499-yefxrj30	302	14	with	with	IN
cord-010499-yefxrj30	302	15	synthetic	synthetic	JJ
cord-010499-yefxrj30	302	16	universal	universal	JJ
cord-010499-yefxrj30	302	17	primers	primer	NNS
cord-010499-yefxrj30	302	18	Mechanism	Mechanism	NNP
cord-010499-yefxrj30	302	19	of	of	IN
cord-010499-yefxrj30	302	20	ribosome	ribosome	NN
cord-010499-yefxrj30	302	21	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	302	22	during	during	IN
cord-010499-yefxrj30	302	23	translation	translation	NN
cord-010499-yefxrj30	302	24	of	of	IN
cord-010499-yefxrj30	302	25	the	the	DT
cord-010499-yefxrj30	302	26	genetic	genetic	JJ
cord-010499-yefxrj30	302	27	code	code	NN
cord-010499-yefxrj30	303	1	Frameshifting	frameshifte	VBG
cord-010499-yefxrj30	303	2	suppression	suppression	NN
cord-010499-yefxrj30	303	3	in	in	IN
cord-010499-yefxrj30	303	4	aminoacyl	aminoacyl	NNP
cord-010499-yefxrj30	303	5	-	-	HYPH
cord-010499-yefxrj30	303	6	tRNA	trna	NN
cord-010499-yefxrj30	303	7	limited	limited	JJ
cord-010499-yefxrj30	303	8	cells	cell	NNS
cord-010499-yefxrj30	303	9	Slippery	slippery	JJ
cord-010499-yefxrj30	303	10	runs	run	NNS
cord-010499-yefxrj30	303	11	,	,	,
cord-010499-yefxrj30	303	12	shifty	shifty	JJ
cord-010499-yefxrj30	303	13	stops	stop	NNS
cord-010499-yefxrj30	303	14	,	,	,
cord-010499-yefxrj30	303	15	backward	backward	JJ
cord-010499-yefxrj30	303	16	steps	step	NNS
cord-010499-yefxrj30	303	17	,	,	,
cord-010499-yefxrj30	303	18	and	and	CC
cord-010499-yefxrj30	303	19	forward	forward	JJ
cord-010499-yefxrj30	303	20	hops	hop	NNS
cord-010499-yefxrj30	303	21	:	:	:
cord-010499-yefxrj30	304	1	-2	-2	NNP
cord-010499-yefxrj30	304	2	,	,	,
cord-010499-yefxrj30	305	1	-1	-1	CC
cord-010499-yefxrj30	305	2	,	,	,
cord-010499-yefxrj30	305	3	+1	+1	XX
cord-010499-yefxrj30	305	4	,	,	,
cord-010499-yefxrj30	305	5	+2	+2	NNP
cord-010499-yefxrj30	305	6	,	,	,
cord-010499-yefxrj30	305	7	-i-5	-i-5	ADD
cord-010499-yefxrj30	305	8	.	.	.
cord-010499-yefxrj30	306	1	and	and	CC
cord-010499-yefxrj30	306	2	+6	+6	CD
cord-010499-yefxrj30	306	3	ribosomal	ribosomal	NN
cord-010499-yefxrj30	306	4	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	306	5	On	on	IN
cord-010499-yefxrj30	306	6	the	the	DT
cord-010499-yefxrj30	306	7	mechanism	mechanism	NN
cord-010499-yefxrj30	306	8	of	of	IN
cord-010499-yefxrj30	306	9	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	306	10	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	306	11	at	at	IN
cord-010499-yefxrj30	307	1	hungry	hungry	JJ
cord-010499-yefxrj30	307	2	codons	codon	NNS
cord-010499-yefxrj30	307	3	E.	E.	NNP
cord-010499-yefxrj30	307	4	coli	coli	NNS
cord-010499-yefxrj30	307	5	ribosomes	ribosome	NNS
cord-010499-yefxrj30	307	6	re	re	NN
cord-010499-yefxrj30	307	7	-	-	NN
cord-010499-yefxrj30	307	8	phase	phase	NN
cord-010499-yefxrj30	308	1	on	on	IN
cord-010499-yefxrj30	308	2	retroviral	retroviral	JJ
cord-010499-yefxrj30	308	3	frameshift	frameshift	NN
cord-010499-yefxrj30	308	4	signals	signal	NNS
cord-010499-yefxrj30	308	5	at	at	IN
cord-010499-yefxrj30	308	6	rates	rate	NNS
cord-010499-yefxrj30	308	7	ranging	range	VBG
cord-010499-yefxrj30	308	8	from	from	IN
cord-010499-yefxrj30	308	9	2	2	CD
cord-010499-yefxrj30	308	10	to	to	TO
cord-010499-yefxrj30	308	11	50	50	CD
cord-010499-yefxrj30	308	12	percent	percent	NN
cord-010499-yefxrj30	308	13	HIV	HIV	NNP
cord-010499-yefxrj30	308	14	expression	expression	NN
cord-010499-yefxrj30	308	15	strategies	strategy	NNS
cord-010499-yefxrj30	309	1	:	:	:
cord-010499-yefxrj30	309	2	ribosomal	ribosomal	JJ
cord-010499-yefxrj30	309	3	frameshifting	frameshifte	VBG
cord-010499-yefxrj30	309	4	is	be	VBZ
cord-010499-yefxrj30	309	5	directed	direct	VBN
cord-010499-yefxrj30	309	6	by	by	IN
cord-010499-yefxrj30	309	7	a	a	DT
cord-010499-yefxrj30	309	8	short	short	JJ
cord-010499-yefxrj30	309	9	sequence	sequence	NN
cord-010499-yefxrj30	309	10	in	in	IN
cord-010499-yefxrj30	309	11	both	both	DT
cord-010499-yefxrj30	309	12	mammalian	mammalian	JJ
cord-010499-yefxrj30	309	13	and	and	CC
cord-010499-yefxrj30	309	14	yeast	yeast	NN
cord-010499-yefxrj30	309	15	systems	system	NNS
cord-010499-yefxrj30	309	16	Differential	differential	JJ
cord-010499-yefxrj30	309	17	sensitivity	sensitivity	NN
cord-010499-yefxrj30	309	18	of	of	IN
cord-010499-yefxrj30	309	19	gene	gene	NN
cord-010499-yefxrj30	309	20	expression	expression	NN
cord-010499-yefxrj30	309	21	in	in	IN
cord-010499-yefxrj30	309	22	vitroio	vitroio	NNP
cord-010499-yefxrj30	309	23	inhibitation	inhibitation	NN
cord-010499-yefxrj30	309	24	of	of	IN
cord-010499-yefxrj30	309	25	DNA	DNA	NNP
cord-010499-yefxrj30	310	1	gyrase	gyrase	NNP
cord-010499-yefxrj30	311	1	This	this	DT
cord-010499-yefxrj30	311	2	work	work	NN
cord-010499-yefxrj30	311	3	was	be	VBD
cord-010499-yefxrj30	311	4	supported	support	VBN
cord-010499-yefxrj30	311	5	by	by	IN
cord-010499-yefxrj30	311	6	Grant	Grant	NNP
cord-010499-yefxrj30	311	7	GM13626	GM13626	NNP
cord-010499-yefxrj30	311	8	and	and	CC
cord-010499-yefxrj30	311	9	from	from	IN
cord-010499-yefxrj30	311	10	Grant	Grant	NNP
cord-010499-yefxrj30	311	11	GM07735	GM07735	NNP
cord-010499-yefxrj30	311	12	from	from	IN
cord-010499-yefxrj30	311	13	the	the	DT
cord-010499-yefxrj30	311	14	National	National	NNP
cord-010499-yefxrj30	311	15	Institutes	Institutes	NNPS
cord-010499-yefxrj30	311	16	of	of	IN
cord-010499-yefxrj30	311	17	Health	Health	NNP
cord-010499-yefxrj30	311	18	.	.	.