id	sid	tid	token	lemma	pos
cord-008530-yni0poh9	1	1	key	key	JJ
cord-008530-yni0poh9	2	1	:	:	:
cord-008530-yni0poh9	2	2	cord-008530-yni0poh9	cord-008530-yni0poh9	NN
cord-008530-yni0poh9	2	3	authors	author	NNS
cord-008530-yni0poh9	2	4	:	:	:
cord-008530-yni0poh9	3	1	Asensio	Asensio	NNP
cord-008530-yni0poh9	3	2	,	,	,
cord-008530-yni0poh9	3	3	Valerie	Valerie	NNP
cord-008530-yni0poh9	3	4	C.	C.	NNP
cord-008530-yni0poh9	3	5	;	;	:
cord-008530-yni0poh9	3	6	Campbell	Campbell	NNP
cord-008530-yni0poh9	3	7	,	,	,
cord-008530-yni0poh9	3	8	lain	lain	NNP
cord-008530-yni0poh9	3	9	L.	L.	NNP
cord-008530-yni0poh9	3	10	title	title	NN
cord-008530-yni0poh9	3	11	:	:	:
cord-008530-yni0poh9	3	12	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	3	13	and	and	CC
cord-008530-yni0poh9	3	14	viral	viral	JJ
cord-008530-yni0poh9	3	15	diseases	disease	NNS
cord-008530-yni0poh9	3	16	of	of	IN
cord-008530-yni0poh9	3	17	the	the	DT
cord-008530-yni0poh9	3	18	central	central	JJ
cord-008530-yni0poh9	3	19	nervous	nervous	JJ
cord-008530-yni0poh9	3	20	system	system	NN
cord-008530-yni0poh9	3	21	date	date	NN
cord-008530-yni0poh9	3	22	:	:	:
cord-008530-yni0poh9	3	23	2004	2004	CD
cord-008530-yni0poh9	3	24	-	-	HYPH
cord-008530-yni0poh9	3	25	01	01	CD
cord-008530-yni0poh9	3	26	-	-	HYPH
cord-008530-yni0poh9	3	27	07	07	CD
cord-008530-yni0poh9	3	28	journal	journal	NN
cord-008530-yni0poh9	3	29	:	:	:
cord-008530-yni0poh9	4	1	Adv	Adv	NNP
cord-008530-yni0poh9	4	2	Virus	virus	NN
cord-008530-yni0poh9	4	3	Res	res	NN
cord-008530-yni0poh9	4	4	DOI	doi	NN
cord-008530-yni0poh9	4	5	:	:	:
cord-008530-yni0poh9	4	6	10.1016	10.1016	CD
cord-008530-yni0poh9	4	7	/	/	SYM
cord-008530-yni0poh9	4	8	s0065	s0065	NNP
cord-008530-yni0poh9	4	9	-	-	HYPH
cord-008530-yni0poh9	4	10	3527(01)56006	3527(01)56006	CD
cord-008530-yni0poh9	4	11	-	-	HYPH
cord-008530-yni0poh9	4	12	6	6	CD
cord-008530-yni0poh9	4	13	sha	sha	NNP
cord-008530-yni0poh9	4	14	:	:	:
cord-008530-yni0poh9	4	15	712572f991348c2b9c14640b655113e4cd74b6a2	712572f991348c2b9c14640b655113e4cd74b6a2	CD
cord-008530-yni0poh9	4	16	doc_id	doc_id	NNPS
cord-008530-yni0poh9	4	17	:	:	:
cord-008530-yni0poh9	4	18	8530	8530	CD
cord-008530-yni0poh9	4	19	cord_uid	cord_uid	FW
cord-008530-yni0poh9	4	20	:	:	:
cord-008530-yni0poh9	5	1	yni0poh9	yni0poh9	NNP
cord-008530-yni0poh9	6	1	This	this	DT
cord-008530-yni0poh9	6	2	chapter	chapter	NN
cord-008530-yni0poh9	6	3	discusses	discuss	VBZ
cord-008530-yni0poh9	6	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	6	5	and	and	CC
cord-008530-yni0poh9	6	6	their	-PRON-	PRP$
cord-008530-yni0poh9	6	7	receptors	receptor	NNS
cord-008530-yni0poh9	6	8	in	in	IN
cord-008530-yni0poh9	6	9	the	the	DT
cord-008530-yni0poh9	6	10	evolution	evolution	NN
cord-008530-yni0poh9	6	11	of	of	IN
cord-008530-yni0poh9	6	12	viral	viral	JJ
cord-008530-yni0poh9	6	13	infectious	infectious	JJ
cord-008530-yni0poh9	6	14	diseases	disease	NNS
cord-008530-yni0poh9	6	15	of	of	IN
cord-008530-yni0poh9	6	16	the	the	DT
cord-008530-yni0poh9	6	17	central	central	JJ
cord-008530-yni0poh9	6	18	nervous	nervous	JJ
cord-008530-yni0poh9	6	19	system	system	NN
cord-008530-yni0poh9	6	20	(	(	-LRB-
cord-008530-yni0poh9	6	21	CNS	CNS	NNP
cord-008530-yni0poh9	6	22	)	)	-RRB-
cord-008530-yni0poh9	6	23	.	.	.
cord-008530-yni0poh9	7	1	Infection	infection	NN
cord-008530-yni0poh9	7	2	of	of	IN
cord-008530-yni0poh9	7	3	the	the	DT
cord-008530-yni0poh9	7	4	human	human	JJ
cord-008530-yni0poh9	7	5	CNS	CNS	NNP
cord-008530-yni0poh9	7	6	with	with	IN
cord-008530-yni0poh9	7	7	many	many	JJ
cord-008530-yni0poh9	7	8	different	different	JJ
cord-008530-yni0poh9	7	9	viruses	virus	NNS
cord-008530-yni0poh9	7	10	or	or	CC
cord-008530-yni0poh9	7	11	infection	infection	NN
cord-008530-yni0poh9	7	12	of	of	IN
cord-008530-yni0poh9	7	13	the	the	DT
cord-008530-yni0poh9	7	14	rodent	rodent	NN
cord-008530-yni0poh9	7	15	CNS	CNS	NNP
cord-008530-yni0poh9	7	16	induces	induce	VBZ
cord-008530-yni0poh9	7	17	vigorous	vigorous	JJ
cord-008530-yni0poh9	7	18	host	host	NN
cord-008530-yni0poh9	7	19	-	-	HYPH
cord-008530-yni0poh9	7	20	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	7	21	responses	response	NNS
cord-008530-yni0poh9	7	22	with	with	IN
cord-008530-yni0poh9	7	23	recruitment	recruitment	NN
cord-008530-yni0poh9	7	24	of	of	IN
cord-008530-yni0poh9	7	25	large	large	JJ
cord-008530-yni0poh9	7	26	numbers	number	NNS
cord-008530-yni0poh9	7	27	of	of	IN
cord-008530-yni0poh9	7	28	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	7	29	,	,	,
cord-008530-yni0poh9	7	30	particularly	particularly	RB
cord-008530-yni0poh9	7	31	T	T	NNP
cord-008530-yni0poh9	7	32	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	7	33	and	and	CC
cord-008530-yni0poh9	7	34	macrophages	macrophage	NNS
cord-008530-yni0poh9	7	35	.	.	.
cord-008530-yni0poh9	8	1	Chemokines	chemokine	NNS
cord-008530-yni0poh9	8	2	coordinate	coordinate	VBP
cord-008530-yni0poh9	8	3	trafficking	trafficking	NN
cord-008530-yni0poh9	8	4	of	of	IN
cord-008530-yni0poh9	8	5	peripheral	peripheral	JJ
cord-008530-yni0poh9	8	6	blood	blood	NN
cord-008530-yni0poh9	8	7	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	8	8	by	by	IN
cord-008530-yni0poh9	8	9	stimulating	stimulate	VBG
cord-008530-yni0poh9	8	10	their	-PRON-	PRP$
cord-008530-yni0poh9	8	11	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	8	12	,	,	,
cord-008530-yni0poh9	8	13	adhesion	adhesion	NN
cord-008530-yni0poh9	8	14	,	,	,
cord-008530-yni0poh9	8	15	extravasation	extravasation	NN
cord-008530-yni0poh9	8	16	,	,	,
cord-008530-yni0poh9	8	17	and	and	CC
cord-008530-yni0poh9	8	18	other	other	JJ
cord-008530-yni0poh9	8	19	effector	effector	NN
cord-008530-yni0poh9	8	20	functions	function	NNS
cord-008530-yni0poh9	8	21	.	.	.
cord-008530-yni0poh9	9	1	In	in	IN
cord-008530-yni0poh9	9	2	view	view	NN
cord-008530-yni0poh9	9	3	of	of	IN
cord-008530-yni0poh9	9	4	these	these	DT
cord-008530-yni0poh9	9	5	properties	property	NNS
cord-008530-yni0poh9	9	6	,	,	,
cord-008530-yni0poh9	9	7	research	research	NN
cord-008530-yni0poh9	9	8	efforts	effort	NNS
cord-008530-yni0poh9	9	9	have	have	VBP
cord-008530-yni0poh9	9	10	turned	turn	VBN
cord-008530-yni0poh9	9	11	increasingly	increasingly	RB
cord-008530-yni0poh9	9	12	to	to	IN
cord-008530-yni0poh9	9	13	the	the	DT
cord-008530-yni0poh9	9	14	possible	possible	JJ
cord-008530-yni0poh9	9	15	involvement	involvement	NN
cord-008530-yni0poh9	9	16	of	of	IN
cord-008530-yni0poh9	9	17	chemokines	chemokine	NNS
cord-008530-yni0poh9	9	18	in	in	IN
cord-008530-yni0poh9	9	19	regulating	regulate	VBG
cord-008530-yni0poh9	9	20	both	both	DT
cord-008530-yni0poh9	9	21	peripheral	peripheral	JJ
cord-008530-yni0poh9	9	22	tissue	tissue	NN
cord-008530-yni0poh9	9	23	and	and	CC
cord-008530-yni0poh9	9	24	CNS	cns	JJ
cord-008530-yni0poh9	9	25	leukocyte	leukocyte	NN
cord-008530-yni0poh9	9	26	migration	migration	NN
cord-008530-yni0poh9	9	27	during	during	IN
cord-008530-yni0poh9	9	28	viral	viral	JJ
cord-008530-yni0poh9	9	29	infection	infection	NN
cord-008530-yni0poh9	9	30	.	.	.
cord-008530-yni0poh9	10	1	The	the	DT
cord-008530-yni0poh9	10	2	biological	biological	JJ
cord-008530-yni0poh9	10	3	effects	effect	NNS
cord-008530-yni0poh9	10	4	of	of	IN
cord-008530-yni0poh9	10	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	10	6	are	be	VBP
cord-008530-yni0poh9	10	7	mediated	mediate	VBN
cord-008530-yni0poh9	10	8	via	via	IN
cord-008530-yni0poh9	10	9	their	-PRON-	PRP$
cord-008530-yni0poh9	10	10	interaction	interaction	NN
cord-008530-yni0poh9	10	11	with	with	IN
cord-008530-yni0poh9	10	12	receptors	receptor	NNS
cord-008530-yni0poh9	10	13	belonging	belong	VBG
cord-008530-yni0poh9	10	14	to	to	IN
cord-008530-yni0poh9	10	15	the	the	DT
cord-008530-yni0poh9	10	16	family	family	NN
cord-008530-yni0poh9	10	17	of	of	IN
cord-008530-yni0poh9	10	18	seven	seven	CD
cord-008530-yni0poh9	10	19	transmembrane	transmembrane	NNP
cord-008530-yni0poh9	10	20	(	(	-LRB-
cord-008530-yni0poh9	10	21	7TM)-spanning	7TM)-spanning	NNP
cord-008530-yni0poh9	10	22	,	,	,
cord-008530-yni0poh9	10	23	G	g	NN
cord-008530-yni0poh9	10	24	-	-	HYPH
cord-008530-yni0poh9	10	25	protein	protein	NN
cord-008530-yni0poh9	10	26	coupled	coupled	JJ
cord-008530-yni0poh9	10	27	receptors	receptor	NNS
cord-008530-yni0poh9	10	28	(	(	-LRB-
cord-008530-yni0poh9	10	29	GPCRs	GPCRs	NNP
cord-008530-yni0poh9	10	30	)	)	-RRB-
cord-008530-yni0poh9	10	31	.	.	.
cord-008530-yni0poh9	11	1	In	in	IN
cord-008530-yni0poh9	11	2	the	the	DT
cord-008530-yni0poh9	11	3	normal	normal	JJ
cord-008530-yni0poh9	11	4	mammalian	mammalian	JJ
cord-008530-yni0poh9	11	5	CNS	CNS	NNP
cord-008530-yni0poh9	11	6	,	,	,
cord-008530-yni0poh9	11	7	the	the	DT
cord-008530-yni0poh9	11	8	number	number	NN
cord-008530-yni0poh9	11	9	of	of	IN
cord-008530-yni0poh9	11	10	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	11	11	present	present	JJ
cord-008530-yni0poh9	11	12	in	in	IN
cord-008530-yni0poh9	11	13	the	the	DT
cord-008530-yni0poh9	11	14	brain	brain	NN
cord-008530-yni0poh9	11	15	is	be	VBZ
cord-008530-yni0poh9	11	16	scant	scant	JJ
cord-008530-yni0poh9	11	17	.	.	.
cord-008530-yni0poh9	12	1	However	however	RB
cord-008530-yni0poh9	12	2	,	,	,
cord-008530-yni0poh9	12	3	these	these	DT
cord-008530-yni0poh9	12	4	cells	cell	NNS
cord-008530-yni0poh9	12	5	are	be	VBP
cord-008530-yni0poh9	12	6	attracted	attract	VBN
cord-008530-yni0poh9	12	7	to	to	IN
cord-008530-yni0poh9	12	8	,	,	,
cord-008530-yni0poh9	12	9	and	and	CC
cord-008530-yni0poh9	12	10	accumulate	accumulate	VB
cord-008530-yni0poh9	12	11	in	in	RP
cord-008530-yni0poh9	12	12	,	,	,
cord-008530-yni0poh9	12	13	a	a	DT
cord-008530-yni0poh9	12	14	variety	variety	NN
cord-008530-yni0poh9	12	15	of	of	IN
cord-008530-yni0poh9	12	16	pathologic	pathologic	JJ
cord-008530-yni0poh9	12	17	states	state	NNS
cord-008530-yni0poh9	12	18	,	,	,
cord-008530-yni0poh9	12	19	many	many	JJ
cord-008530-yni0poh9	12	20	involving	involve	VBG
cord-008530-yni0poh9	12	21	viral	viral	JJ
cord-008530-yni0poh9	12	22	infection	infection	NN
cord-008530-yni0poh9	12	23	.	.	.
cord-008530-yni0poh9	13	1	Although	although	IN
cord-008530-yni0poh9	13	2	leukocyte	leukocyte	NN
cord-008530-yni0poh9	13	3	migration	migration	NN
cord-008530-yni0poh9	13	4	into	into	IN
cord-008530-yni0poh9	13	5	local	local	JJ
cord-008530-yni0poh9	13	6	tissue	tissue	NN
cord-008530-yni0poh9	13	7	compartments	compartment	NNS
cord-008530-yni0poh9	13	8	,	,	,
cord-008530-yni0poh9	13	9	such	such	JJ
cord-008530-yni0poh9	13	10	as	as	IN
cord-008530-yni0poh9	13	11	the	the	DT
cord-008530-yni0poh9	13	12	CNS	CNS	NNP
cord-008530-yni0poh9	13	13	,	,	,
cord-008530-yni0poh9	13	14	is	be	VBZ
cord-008530-yni0poh9	13	15	a	a	DT
cord-008530-yni0poh9	13	16	multifactorial	multifactorial	JJ
cord-008530-yni0poh9	13	17	process	process	NN
cord-008530-yni0poh9	13	18	,	,	,
cord-008530-yni0poh9	13	19	it	-PRON-	PRP
cord-008530-yni0poh9	13	20	has	have	VBZ
cord-008530-yni0poh9	13	21	become	become	VBN
cord-008530-yni0poh9	13	22	clear	clear	JJ
cord-008530-yni0poh9	13	23	that	that	IN
cord-008530-yni0poh9	13	24	chemokines	chemokine	NNS
cord-008530-yni0poh9	13	25	are	be	VBP
cord-008530-yni0poh9	13	26	pivotal	pivotal	JJ
cord-008530-yni0poh9	13	27	components	component	NNS
cord-008530-yni0poh9	13	28	of	of	IN
cord-008530-yni0poh9	13	29	this	this	DT
cord-008530-yni0poh9	13	30	process	process	NN
cord-008530-yni0poh9	13	31	,	,	,
cord-008530-yni0poh9	13	32	providing	provide	VBG
cord-008530-yni0poh9	13	33	a	a	DT
cord-008530-yni0poh9	13	34	necessary	necessary	JJ
cord-008530-yni0poh9	13	35	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	13	36	signal	signal	NN
cord-008530-yni0poh9	13	37	for	for	IN
cord-008530-yni0poh9	13	38	leukocyte	leukocyte	NN
cord-008530-yni0poh9	13	39	recruitment	recruitment	NN
cord-008530-yni0poh9	13	40	.	.	.
cord-008530-yni0poh9	14	1	The	the	DT
cord-008530-yni0poh9	14	2	central	central	JJ
cord-008530-yni0poh9	14	3	nervous	nervous	JJ
cord-008530-yni0poh9	14	4	system	system	NN
cord-008530-yni0poh9	14	5	(	(	-LRB-
cord-008530-yni0poh9	14	6	CNS	CNS	NNP
cord-008530-yni0poh9	14	7	)	)	-RRB-
cord-008530-yni0poh9	14	8	has	have	VBZ
cord-008530-yni0poh9	14	9	been	be	VBN
cord-008530-yni0poh9	14	10	viewed	view	VBN
cord-008530-yni0poh9	14	11	as	as	IN
cord-008530-yni0poh9	14	12	a	a	DT
cord-008530-yni0poh9	14	13	relatively	relatively	RB
cord-008530-yni0poh9	14	14	immune	immune	JJ
cord-008530-yni0poh9	14	15	privileged	privileged	JJ
cord-008530-yni0poh9	14	16	organ	organ	NN
cord-008530-yni0poh9	14	17	.	.	.
cord-008530-yni0poh9	15	1	In	in	IN
cord-008530-yni0poh9	15	2	physiologic	physiologic	JJ
cord-008530-yni0poh9	15	3	states	state	NNS
cord-008530-yni0poh9	15	4	,	,	,
cord-008530-yni0poh9	15	5	the	the	DT
cord-008530-yni0poh9	15	6	CNS	CNS	NNP
cord-008530-yni0poh9	15	7	contains	contain	VBZ
cord-008530-yni0poh9	15	8	few	few	JJ
cord-008530-yni0poh9	15	9	,	,	,
cord-008530-yni0poh9	15	10	if	if	IN
cord-008530-yni0poh9	15	11	any	any	DT
cord-008530-yni0poh9	15	12	,	,	,
cord-008530-yni0poh9	15	13	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	15	14	,	,	,
cord-008530-yni0poh9	15	15	and	and	CC
cord-008530-yni0poh9	15	16	an	an	DT
cord-008530-yni0poh9	15	17	absence	absence	NN
cord-008530-yni0poh9	15	18	of	of	IN
cord-008530-yni0poh9	15	19	professional	professional	JJ
cord-008530-yni0poh9	15	20	antigen	antigen	NN
cord-008530-yni0poh9	15	21	-	-	HYPH
cord-008530-yni0poh9	15	22	presenting	present	VBG
cord-008530-yni0poh9	15	23	cells	cell	NNS
cord-008530-yni0poh9	15	24	(	(	-LRB-
cord-008530-yni0poh9	15	25	APC	APC	NNP
cord-008530-yni0poh9	15	26	)	)	-RRB-
cord-008530-yni0poh9	15	27	;	;	:
cord-008530-yni0poh9	15	28	it	-PRON-	PRP
cord-008530-yni0poh9	15	29	is	be	VBZ
cord-008530-yni0poh9	15	30	barren	barren	JJ
cord-008530-yni0poh9	15	31	for	for	IN
cord-008530-yni0poh9	15	32	the	the	DT
cord-008530-yni0poh9	15	33	expression	expression	NN
cord-008530-yni0poh9	15	34	of	of	IN
cord-008530-yni0poh9	15	35	key	key	JJ
cord-008530-yni0poh9	15	36	immune	immune	JJ
cord-008530-yni0poh9	15	37	accessory	accessory	NN
cord-008530-yni0poh9	15	38	molecules	molecule	NNS
cord-008530-yni0poh9	15	39	such	such	JJ
cord-008530-yni0poh9	15	40	as	as	IN
cord-008530-yni0poh9	15	41	major	major	JJ
cord-008530-yni0poh9	15	42	histocompatibility	histocompatibility	NN
cord-008530-yni0poh9	15	43	molecules	molecule	NNS
cord-008530-yni0poh9	15	44	(	(	-LRB-
cord-008530-yni0poh9	15	45	MHCs	MHCs	NNPS
cord-008530-yni0poh9	15	46	)	)	-RRB-
cord-008530-yni0poh9	15	47	,	,	,
cord-008530-yni0poh9	15	48	and	and	CC
cord-008530-yni0poh9	15	49	is	be	VBZ
cord-008530-yni0poh9	15	50	fortified	fortify	VBN
cord-008530-yni0poh9	15	51	by	by	IN
cord-008530-yni0poh9	15	52	an	an	DT
cord-008530-yni0poh9	15	53	effective	effective	JJ
cord-008530-yni0poh9	15	54	blood	blood	NN
cord-008530-yni0poh9	15	55	-	-	HYPH
cord-008530-yni0poh9	15	56	brain	brain	NN
cord-008530-yni0poh9	15	57	barrier	barrier	NN
cord-008530-yni0poh9	15	58	.	.	.
cord-008530-yni0poh9	16	1	Nevertheless	nevertheless	RB
cord-008530-yni0poh9	16	2	,	,	,
cord-008530-yni0poh9	16	3	the	the	DT
cord-008530-yni0poh9	16	4	past	past	JJ
cord-008530-yni0poh9	16	5	decade	decade	NN
cord-008530-yni0poh9	16	6	has	have	VBZ
cord-008530-yni0poh9	16	7	witnessed	witness	VBN
cord-008530-yni0poh9	16	8	a	a	DT
cord-008530-yni0poh9	16	9	revision	revision	NN
cord-008530-yni0poh9	16	10	of	of	IN
cord-008530-yni0poh9	16	11	this	this	DT
cord-008530-yni0poh9	16	12	concept	concept	NN
cord-008530-yni0poh9	16	13	,	,	,
cord-008530-yni0poh9	16	14	as	as	IN
cord-008530-yni0poh9	16	15	evidenced	evidence	VBN
cord-008530-yni0poh9	16	16	by	by	IN
cord-008530-yni0poh9	16	17	the	the	DT
cord-008530-yni0poh9	16	18	fact	fact	NN
cord-008530-yni0poh9	16	19	that	that	WDT
cord-008530-yni0poh9	16	20	activated	activate	VBD
cord-008530-yni0poh9	16	21	T	t	NN
cord-008530-yni0poh9	16	22	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	16	23	,	,	,
cord-008530-yni0poh9	16	24	regardless	regardless	RB
cord-008530-yni0poh9	16	25	of	of	IN
cord-008530-yni0poh9	16	26	their	-PRON-	PRP$
cord-008530-yni0poh9	16	27	antigen	antigen	NN
cord-008530-yni0poh9	16	28	specificity	specificity	NN
cord-008530-yni0poh9	16	29	,	,	,
cord-008530-yni0poh9	16	30	migrate	migrate	VB
cord-008530-yni0poh9	16	31	effectively	effectively	RB
cord-008530-yni0poh9	16	32	through	through	IN
cord-008530-yni0poh9	16	33	the	the	DT
cord-008530-yni0poh9	16	34	blood	blood	NN
cord-008530-yni0poh9	16	35	-	-	HYPH
cord-008530-yni0poh9	16	36	brain	brain	NN
cord-008530-yni0poh9	16	37	barrier	barrier	NN
cord-008530-yni0poh9	16	38	(	(	-LRB-
cord-008530-yni0poh9	16	39	BBB	BBB	NNP
cord-008530-yni0poh9	16	40	)	)	-RRB-
cord-008530-yni0poh9	16	41	,	,	,
cord-008530-yni0poh9	16	42	but	but	CC
cord-008530-yni0poh9	16	43	also	also	RB
cord-008530-yni0poh9	16	44	by	by	IN
cord-008530-yni0poh9	16	45	the	the	DT
cord-008530-yni0poh9	16	46	fact	fact	NN
cord-008530-yni0poh9	16	47	that	that	IN
cord-008530-yni0poh9	16	48	the	the	DT
cord-008530-yni0poh9	16	49	CNS	CNS	NNP
cord-008530-yni0poh9	16	50	contains	contain	VBZ
cord-008530-yni0poh9	16	51	numerous	numerous	JJ
cord-008530-yni0poh9	16	52	resident	resident	JJ
cord-008530-yni0poh9	16	53	cells	cell	NNS
cord-008530-yni0poh9	16	54	,	,	,
cord-008530-yni0poh9	16	55	such	such	JJ
cord-008530-yni0poh9	16	56	as	as	IN
cord-008530-yni0poh9	16	57	microglia	microglia	NN
cord-008530-yni0poh9	16	58	,	,	,
cord-008530-yni0poh9	16	59	cerebral	cerebral	JJ
cord-008530-yni0poh9	16	60	endothelial	endothelial	JJ
cord-008530-yni0poh9	16	61	cells	cell	NNS
cord-008530-yni0poh9	16	62	,	,	,
cord-008530-yni0poh9	16	63	and	and	CC
cord-008530-yni0poh9	16	64	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	16	65	,	,	,
cord-008530-yni0poh9	16	66	that	that	DT
cord-008530-yni0poh9	16	67	can	can	MD
cord-008530-yni0poh9	16	68	,	,	,
cord-008530-yni0poh9	16	69	under	under	IN
cord-008530-yni0poh9	16	70	the	the	DT
cord-008530-yni0poh9	16	71	appropriate	appropriate	JJ
cord-008530-yni0poh9	16	72	conditions	condition	NNS
cord-008530-yni0poh9	16	73	,	,	,
cord-008530-yni0poh9	16	74	acquire	acquire	VB
cord-008530-yni0poh9	16	75	the	the	DT
cord-008530-yni0poh9	16	76	expression	expression	NN
cord-008530-yni0poh9	16	77	of	of	IN
cord-008530-yni0poh9	16	78	immune	immune	JJ
cord-008530-yni0poh9	16	79	accessory	accessory	NN
cord-008530-yni0poh9	16	80	molecules	molecule	NNS
cord-008530-yni0poh9	16	81	and	and	CC
cord-008530-yni0poh9	16	82	may	may	MD
cord-008530-yni0poh9	16	83	function	function	VB
cord-008530-yni0poh9	16	84	as	as	IN
cord-008530-yni0poh9	16	85	APC	APC	NNP
cord-008530-yni0poh9	16	86	(	(	-LRB-
cord-008530-yni0poh9	16	87	Hickey	Hickey	NNP
cord-008530-yni0poh9	16	88	,	,	,
cord-008530-yni0poh9	16	89	1999	1999	CD
cord-008530-yni0poh9	16	90	;	;	:
cord-008530-yni0poh9	16	91	Owens	Owens	NNP
cord-008530-yni0poh9	16	92	et	et	NNP
cord-008530-yni0poh9	16	93	al	al	NNP
cord-008530-yni0poh9	16	94	.	.	NNP
cord-008530-yni0poh9	16	95	,	,	,
cord-008530-yni0poh9	16	96	1994	1994	CD
cord-008530-yni0poh9	16	97	)	)	-RRB-
cord-008530-yni0poh9	16	98	.	.	.
cord-008530-yni0poh9	17	1	Significantly	significantly	RB
cord-008530-yni0poh9	17	2	,	,	,
cord-008530-yni0poh9	17	3	in	in	IN
cord-008530-yni0poh9	17	4	numerous	numerous	JJ
cord-008530-yni0poh9	17	5	pathological	pathological	JJ
cord-008530-yni0poh9	17	6	conditions	condition	NNS
cord-008530-yni0poh9	17	7	,	,	,
cord-008530-yni0poh9	17	8	immune	immune	JJ
cord-008530-yni0poh9	17	9	cells	cell	NNS
cord-008530-yni0poh9	17	10	are	be	VBP
cord-008530-yni0poh9	17	11	readily	readily	RB
cord-008530-yni0poh9	17	12	recruited	recruit	VBN
cord-008530-yni0poh9	17	13	to	to	IN
cord-008530-yni0poh9	17	14	and	and	CC
cord-008530-yni0poh9	17	15	accumulate	accumulate	VB
cord-008530-yni0poh9	17	16	in	in	IN
cord-008530-yni0poh9	17	17	the	the	DT
cord-008530-yni0poh9	17	18	CNS	CNS	NNP
cord-008530-yni0poh9	17	19	.	.	.
cord-008530-yni0poh9	18	1	Infection	infection	NN
cord-008530-yni0poh9	18	2	of	of	IN
cord-008530-yni0poh9	18	3	the	the	DT
cord-008530-yni0poh9	18	4	human	human	JJ
cord-008530-yni0poh9	18	5	CNS	CNS	NNP
cord-008530-yni0poh9	18	6	with	with	IN
cord-008530-yni0poh9	18	7	many	many	JJ
cord-008530-yni0poh9	18	8	different	different	JJ
cord-008530-yni0poh9	18	9	viruses	virus	NNS
cord-008530-yni0poh9	18	10	(	(	-LRB-
cord-008530-yni0poh9	18	11	e.g.	e.g.	RB
cord-008530-yni0poh9	18	12	,	,	,
cord-008530-yni0poh9	18	13	human	human	JJ
cord-008530-yni0poh9	18	14	T	T	NNP
cord-008530-yni0poh9	18	15	cell	cell	NN
cord-008530-yni0poh9	18	16	leukemia	leukemia	NN
cord-008530-yni0poh9	18	17	virus	virus	NN
cord-008530-yni0poh9	18	18	type	type	NN
cord-008530-yni0poh9	18	19	I	-PRON-	PRP
cord-008530-yni0poh9	18	20	[	[	-LRB-
cord-008530-yni0poh9	18	21	HTLV	HTLV	NNP
cord-008530-yni0poh9	18	22	-	-	HYPH
cord-008530-yni0poh9	18	23	I	I	NNP
cord-008530-yni0poh9	18	24	]	]	-RRB-
cord-008530-yni0poh9	18	25	;	;	:
cord-008530-yni0poh9	18	26	measles	measle	NNS
cord-008530-yni0poh9	18	27	virus	virus	NN
cord-008530-yni0poh9	18	28	,	,	,
cord-008530-yni0poh9	18	29	human	human	JJ
cord-008530-yni0poh9	18	30	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	18	31	virus	virus	NN
cord-008530-yni0poh9	18	32	[	[	-LRB-
cord-008530-yni0poh9	18	33	HIV	HIV	NNP
cord-008530-yni0poh9	18	34	]	]	-RRB-
cord-008530-yni0poh9	18	35	type	type	NN
cord-008530-yni0poh9	18	36	1	1	CD
cord-008530-yni0poh9	18	37	;	;	:
cord-008530-yni0poh9	18	38	and	and	CC
cord-008530-yni0poh9	18	39	herpes	herpes	NN
cord-008530-yni0poh9	18	40	simplex	simplex	NNP
cord-008530-yni0poh9	18	41	virus	virus	NN
cord-008530-yni0poh9	18	42	[	[	-LRB-
cord-008530-yni0poh9	18	43	HSV	HSV	NNP
cord-008530-yni0poh9	18	44	]	]	-RRB-
cord-008530-yni0poh9	18	45	type	type	NN
cord-008530-yni0poh9	18	46	2	2	CD
cord-008530-yni0poh9	18	47	)	)	-RRB-
cord-008530-yni0poh9	18	48	,	,	,
cord-008530-yni0poh9	18	49	or	or	CC
cord-008530-yni0poh9	18	50	of	of	IN
cord-008530-yni0poh9	18	51	the	the	DT
cord-008530-yni0poh9	18	52	rodent	rodent	NN
cord-008530-yni0poh9	18	53	CNS	CNS	NNP
cord-008530-yni0poh9	18	54	(	(	-LRB-
cord-008530-yni0poh9	18	55	e.g.	e.g.	RB
cord-008530-yni0poh9	18	56	,	,	,
cord-008530-yni0poh9	18	57	Theiler	Theiler	NNP
cord-008530-yni0poh9	18	58	's	's	POS
cord-008530-yni0poh9	18	59	murine	murine	JJ
cord-008530-yni0poh9	18	60	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	18	61	virus	virus	NN
cord-008530-yni0poh9	18	62	[	[	-LRB-
cord-008530-yni0poh9	18	63	TMEV	TMEV	NNP
cord-008530-yni0poh9	18	64	]	]	-RRB-
cord-008530-yni0poh9	18	65	,	,	,
cord-008530-yni0poh9	18	66	mouse	mouse	NNP
cord-008530-yni0poh9	18	67	hepatitis	hepatitis	NN
cord-008530-yni0poh9	18	68	virus	virus	NN
cord-008530-yni0poh9	18	69	[	[	-LRB-
cord-008530-yni0poh9	18	70	MHV	MHV	NNP
cord-008530-yni0poh9	18	71	]	]	-RRB-
cord-008530-yni0poh9	18	72	,	,	,
cord-008530-yni0poh9	18	73	lymphocytic	lymphocytic	JJ
cord-008530-yni0poh9	18	74	choriomeningitis	choriomeningitis	NNP
cord-008530-yni0poh9	18	75	virus	virus	NN
cord-008530-yni0poh9	18	76	[	[	-LRB-
cord-008530-yni0poh9	18	77	LCMV	LCMV	NNP
cord-008530-yni0poh9	18	78	]	]	-RRB-
cord-008530-yni0poh9	18	79	and	and	CC
cord-008530-yni0poh9	18	80	vesicular	vesicular	JJ
cord-008530-yni0poh9	18	81	stomatitis	stomatitis	NN
cord-008530-yni0poh9	18	82	virus	virus	NN
cord-008530-yni0poh9	18	83	)	)	-RRB-
cord-008530-yni0poh9	18	84	induces	induce	VBZ
cord-008530-yni0poh9	18	85	vigorous	vigorous	JJ
cord-008530-yni0poh9	18	86	host	host	NN
cord-008530-yni0poh9	18	87	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	18	88	responses	response	NNS
cord-008530-yni0poh9	18	89	with	with	IN
cord-008530-yni0poh9	18	90	recruitment	recruitment	NN
cord-008530-yni0poh9	18	91	of	of	IN
cord-008530-yni0poh9	18	92	large	large	JJ
cord-008530-yni0poh9	18	93	numbers	number	NNS
cord-008530-yni0poh9	18	94	of	of	IN
cord-008530-yni0poh9	18	95	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	18	96	,	,	,
cord-008530-yni0poh9	18	97	particularly	particularly	RB
cord-008530-yni0poh9	18	98	T	T	NNP
cord-008530-yni0poh9	18	99	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	18	100	and	and	CC
cord-008530-yni0poh9	18	101	macrophages	macrophage	NNS
cord-008530-yni0poh9	18	102	.	.	.
cord-008530-yni0poh9	19	1	This	this	DT
cord-008530-yni0poh9	19	2	host	host	NN
cord-008530-yni0poh9	19	3	response	response	NN
cord-008530-yni0poh9	19	4	can	can	MD
cord-008530-yni0poh9	19	5	be	be	VB
cord-008530-yni0poh9	19	6	a	a	DT
cord-008530-yni0poh9	19	7	two	two	CD
cord-008530-yni0poh9	19	8	-	-	HYPH
cord-008530-yni0poh9	19	9	edged	edge	VBN
cord-008530-yni0poh9	19	10	sword	sword	NN
cord-008530-yni0poh9	19	11	that	that	WDT
cord-008530-yni0poh9	19	12	,	,	,
cord-008530-yni0poh9	19	13	on	on	IN
cord-008530-yni0poh9	19	14	the	the	DT
cord-008530-yni0poh9	19	15	one	one	CD
cord-008530-yni0poh9	19	16	hand	hand	NN
cord-008530-yni0poh9	19	17	,	,	,
cord-008530-yni0poh9	19	18	is	be	VBZ
cord-008530-yni0poh9	19	19	needed	need	VBN
cord-008530-yni0poh9	19	20	to	to	TO
cord-008530-yni0poh9	19	21	control	control	VB
cord-008530-yni0poh9	19	22	and	and	CC
cord-008530-yni0poh9	19	23	extinguish	extinguish	VB
cord-008530-yni0poh9	19	24	the	the	DT
cord-008530-yni0poh9	19	25	invading	invade	VBG
cord-008530-yni0poh9	19	26	virus	virus	NN
cord-008530-yni0poh9	20	1	but	but	CC
cord-008530-yni0poh9	20	2	,	,	,
cord-008530-yni0poh9	20	3	on	on	IN
cord-008530-yni0poh9	20	4	the	the	DT
cord-008530-yni0poh9	20	5	other	other	JJ
cord-008530-yni0poh9	20	6	,	,	,
cord-008530-yni0poh9	20	7	can	can	MD
cord-008530-yni0poh9	20	8	produce	produce	VB
cord-008530-yni0poh9	20	9	immune	immune	JJ
cord-008530-yni0poh9	20	10	pathology	pathology	NN
cord-008530-yni0poh9	20	11	and	and	CC
cord-008530-yni0poh9	20	12	tissue	tissue	NN
cord-008530-yni0poh9	20	13	injury	injury	NN
cord-008530-yni0poh9	20	14	resulting	result	VBG
cord-008530-yni0poh9	20	15	in	in	IN
cord-008530-yni0poh9	20	16	mental	mental	JJ
cord-008530-yni0poh9	20	17	and	and	CC
cord-008530-yni0poh9	20	18	physical	physical	JJ
cord-008530-yni0poh9	20	19	debilitation	debilitation	NN
cord-008530-yni0poh9	20	20	,	,	,
cord-008530-yni0poh9	20	21	and	and	CC
cord-008530-yni0poh9	20	22	often	often	RB
cord-008530-yni0poh9	20	23	death	death	NN
cord-008530-yni0poh9	20	24	,	,	,
cord-008530-yni0poh9	20	25	of	of	IN
cord-008530-yni0poh9	20	26	the	the	DT
cord-008530-yni0poh9	20	27	host	host	NN
cord-008530-yni0poh9	20	28	organism	organism	NN
cord-008530-yni0poh9	20	29	.	.	.
cord-008530-yni0poh9	21	1	Therefore	therefore	RB
cord-008530-yni0poh9	21	2	,	,	,
cord-008530-yni0poh9	21	3	increasing	increase	VBG
cord-008530-yni0poh9	21	4	our	-PRON-	PRP$
cord-008530-yni0poh9	21	5	knowledge	knowledge	NN
cord-008530-yni0poh9	21	6	of	of	IN
cord-008530-yni0poh9	21	7	the	the	DT
cord-008530-yni0poh9	21	8	mechanisms	mechanism	NNS
cord-008530-yni0poh9	21	9	that	that	WDT
cord-008530-yni0poh9	21	10	control	control	VBP
cord-008530-yni0poh9	21	11	the	the	DT
cord-008530-yni0poh9	21	12	trafficking	trafficking	NN
cord-008530-yni0poh9	21	13	of	of	IN
cord-008530-yni0poh9	21	14	immune	immune	JJ
cord-008530-yni0poh9	21	15	cells	cell	NNS
cord-008530-yni0poh9	21	16	into	into	IN
cord-008530-yni0poh9	21	17	the	the	DT
cord-008530-yni0poh9	21	18	CNS	CNS	NNP
cord-008530-yni0poh9	21	19	,	,	,
cord-008530-yni0poh9	21	20	and	and	CC
cord-008530-yni0poh9	21	21	knowledge	knowledge	NN
cord-008530-yni0poh9	21	22	of	of	IN
cord-008530-yni0poh9	21	23	the	the	DT
cord-008530-yni0poh9	21	24	subsequent	subsequent	JJ
cord-008530-yni0poh9	21	25	interactions	interaction	NNS
cord-008530-yni0poh9	21	26	between	between	IN
cord-008530-yni0poh9	21	27	these	these	DT
cord-008530-yni0poh9	21	28	cells	cell	NNS
cord-008530-yni0poh9	21	29	that	that	WDT
cord-008530-yni0poh9	21	30	contribute	contribute	VBP
cord-008530-yni0poh9	21	31	to	to	IN
cord-008530-yni0poh9	21	32	CNS	CNS	NNP
cord-008530-yni0poh9	21	33	damage	damage	NN
cord-008530-yni0poh9	21	34	,	,	,
cord-008530-yni0poh9	21	35	is	be	VBZ
cord-008530-yni0poh9	21	36	an	an	DT
cord-008530-yni0poh9	21	37	important	important	JJ
cord-008530-yni0poh9	21	38	objective	objective	NN
cord-008530-yni0poh9	21	39	.	.	.
cord-008530-yni0poh9	22	1	Our	-PRON-	PRP$
cord-008530-yni0poh9	22	2	understanding	understanding	NN
cord-008530-yni0poh9	22	3	of	of	IN
cord-008530-yni0poh9	22	4	the	the	DT
cord-008530-yni0poh9	22	5	factors	factor	NNS
cord-008530-yni0poh9	22	6	that	that	WDT
cord-008530-yni0poh9	22	7	govern	govern	VBP
cord-008530-yni0poh9	22	8	leukocyte	leukocyte	NN
cord-008530-yni0poh9	22	9	trafficking	trafficking	NN
cord-008530-yni0poh9	22	10	has	have	VBZ
cord-008530-yni0poh9	22	11	been	be	VBN
cord-008530-yni0poh9	22	12	advanced	advance	VBN
cord-008530-yni0poh9	22	13	considerably	considerably	RB
cord-008530-yni0poh9	22	14	with	with	IN
cord-008530-yni0poh9	22	15	the	the	DT
cord-008530-yni0poh9	22	16	discovery	discovery	NN
cord-008530-yni0poh9	22	17	of	of	IN
cord-008530-yni0poh9	22	18	a	a	DT
cord-008530-yni0poh9	22	19	large	large	JJ
cord-008530-yni0poh9	22	20	superfamily	superfamily	NN
cord-008530-yni0poh9	22	21	of	of	IN
cord-008530-yni0poh9	22	22	mostly	mostly	RB
cord-008530-yni0poh9	22	23	small	small	JJ
cord-008530-yni0poh9	22	24	proteins	protein	NNS
cord-008530-yni0poh9	22	25	(	(	-LRB-
cord-008530-yni0poh9	22	26	termed	termed	JJ
cord-008530-yni0poh9	22	27	chemokines	chemokine	NNS
cord-008530-yni0poh9	22	28	)	)	-RRB-
cord-008530-yni0poh9	22	29	that	that	WDT
cord-008530-yni0poh9	22	30	function	function	VBP
cord-008530-yni0poh9	22	31	as	as	IN
cord-008530-yni0poh9	22	32	leukocyte	leukocyte	NN
cord-008530-yni0poh9	22	33	chemoattractants	chemoattractant	NNS
cord-008530-yni0poh9	22	34	in	in	IN
cord-008530-yni0poh9	22	35	immunoinflammatory	immunoinflammatory	NNP
cord-008530-yni0poh9	22	36	states	states	NNP
cord-008530-yni0poh9	22	37	(	(	-LRB-
cord-008530-yni0poh9	22	38	for	for	IN
cord-008530-yni0poh9	22	39	reviews	review	NNS
cord-008530-yni0poh9	22	40	,	,	,
cord-008530-yni0poh9	22	41	see	see	VB
cord-008530-yni0poh9	22	42	Bacon	Bacon	NNP
cord-008530-yni0poh9	22	43	and	and	CC
cord-008530-yni0poh9	22	44	Oppenheim	Oppenheim	NNP
cord-008530-yni0poh9	22	45	,	,	,
cord-008530-yni0poh9	22	46	1998	1998	CD
cord-008530-yni0poh9	22	47	;	;	:
cord-008530-yni0poh9	22	48	Rollins	Rollins	NNP
cord-008530-yni0poh9	22	49	,	,	,
cord-008530-yni0poh9	22	50	1997	1997	CD
cord-008530-yni0poh9	22	51	;	;	:
cord-008530-yni0poh9	22	52	Taub	Taub	NNP
cord-008530-yni0poh9	22	53	and	and	CC
cord-008530-yni0poh9	22	54	Oppenheim	Oppenheim	NNP
cord-008530-yni0poh9	22	55	,	,	,
cord-008530-yni0poh9	22	56	1994	1994	CD
cord-008530-yni0poh9	22	57	)	)	-RRB-
cord-008530-yni0poh9	22	58	.	.	.
cord-008530-yni0poh9	23	1	Chemokines	chemokine	NNS
cord-008530-yni0poh9	23	2	coordinate	coordinate	VBP
cord-008530-yni0poh9	23	3	trafficking	trafficking	NN
cord-008530-yni0poh9	23	4	of	of	IN
cord-008530-yni0poh9	23	5	peripheral	peripheral	JJ
cord-008530-yni0poh9	23	6	blood	blood	NN
cord-008530-yni0poh9	23	7	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	23	8	by	by	IN
cord-008530-yni0poh9	23	9	stimulating	stimulate	VBG
cord-008530-yni0poh9	23	10	their	-PRON-	PRP$
cord-008530-yni0poh9	23	11	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	23	12	,	,	,
cord-008530-yni0poh9	23	13	adhesion	adhesion	NN
cord-008530-yni0poh9	23	14	,	,	,
cord-008530-yni0poh9	23	15	extravasation	extravasation	NN
cord-008530-yni0poh9	23	16	,	,	,
cord-008530-yni0poh9	23	17	and	and	CC
cord-008530-yni0poh9	23	18	other	other	JJ
cord-008530-yni0poh9	23	19	effector	effector	NN
cord-008530-yni0poh9	23	20	functions	function	NNS
cord-008530-yni0poh9	23	21	.	.	.
cord-008530-yni0poh9	24	1	In	in	IN
cord-008530-yni0poh9	24	2	view	view	NN
cord-008530-yni0poh9	24	3	of	of	IN
cord-008530-yni0poh9	24	4	these	these	DT
cord-008530-yni0poh9	24	5	properties	property	NNS
cord-008530-yni0poh9	24	6	,	,	,
cord-008530-yni0poh9	24	7	research	research	NN
cord-008530-yni0poh9	24	8	efforts	effort	NNS
cord-008530-yni0poh9	24	9	have	have	VBP
cord-008530-yni0poh9	24	10	turned	turn	VBN
cord-008530-yni0poh9	24	11	increasingly	increasingly	RB
cord-008530-yni0poh9	24	12	to	to	IN
cord-008530-yni0poh9	24	13	a	a	DT
cord-008530-yni0poh9	24	14	focus	focus	NN
cord-008530-yni0poh9	24	15	on	on	IN
cord-008530-yni0poh9	24	16	the	the	DT
cord-008530-yni0poh9	24	17	possible	possible	JJ
cord-008530-yni0poh9	24	18	involvement	involvement	NN
cord-008530-yni0poh9	24	19	of	of	IN
cord-008530-yni0poh9	24	20	chemokines	chemokine	NNS
cord-008530-yni0poh9	24	21	in	in	IN
cord-008530-yni0poh9	24	22	regulating	regulate	VBG
cord-008530-yni0poh9	24	23	both	both	DT
cord-008530-yni0poh9	24	24	peripheral	peripheral	JJ
cord-008530-yni0poh9	24	25	tissue	tissue	NN
cord-008530-yni0poh9	24	26	and	and	CC
cord-008530-yni0poh9	24	27	CNS	cns	JJ
cord-008530-yni0poh9	24	28	leukocyte	leukocyte	NN
cord-008530-yni0poh9	24	29	migration	migration	NN
cord-008530-yni0poh9	24	30	during	during	IN
cord-008530-yni0poh9	24	31	viral	viral	JJ
cord-008530-yni0poh9	24	32	infection	infection	NN
cord-008530-yni0poh9	24	33	.	.	.
cord-008530-yni0poh9	25	1	However	however	RB
cord-008530-yni0poh9	25	2	,	,	,
cord-008530-yni0poh9	25	3	it	-PRON-	PRP
cord-008530-yni0poh9	25	4	is	be	VBZ
cord-008530-yni0poh9	25	5	clear	clear	JJ
cord-008530-yni0poh9	25	6	that	that	IN
cord-008530-yni0poh9	25	7	the	the	DT
cord-008530-yni0poh9	25	8	scope	scope	NN
cord-008530-yni0poh9	25	9	of	of	IN
cord-008530-yni0poh9	25	10	chemokine	chemokine	NN
cord-008530-yni0poh9	25	11	involvement	involvement	NN
cord-008530-yni0poh9	25	12	in	in	IN
cord-008530-yni0poh9	25	13	the	the	DT
cord-008530-yni0poh9	25	14	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	25	15	of	of	IN
cord-008530-yni0poh9	25	16	host	host	NN
cord-008530-yni0poh9	25	17	/	/	SYM
cord-008530-yni0poh9	25	18	viral	viral	JJ
cord-008530-yni0poh9	25	19	interactions	interaction	NNS
cord-008530-yni0poh9	25	20	extends	extend	VBZ
cord-008530-yni0poh9	25	21	well	well	RB
cord-008530-yni0poh9	25	22	beyond	beyond	IN
cord-008530-yni0poh9	25	23	leukocyte	leukocyte	NN
cord-008530-yni0poh9	25	24	migration	migration	NN
cord-008530-yni0poh9	25	25	.	.	.
cord-008530-yni0poh9	26	1	With	with	IN
cord-008530-yni0poh9	26	2	studies	study	NNS
cord-008530-yni0poh9	26	3	on	on	IN
cord-008530-yni0poh9	26	4	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	26	5	in	in	IN
cord-008530-yni0poh9	26	6	the	the	DT
cord-008530-yni0poh9	26	7	vanguard	vanguard	NN
cord-008530-yni0poh9	26	8	,	,	,
cord-008530-yni0poh9	26	9	new	new	JJ
cord-008530-yni0poh9	26	10	roles	role	NNS
cord-008530-yni0poh9	26	11	for	for	IN
cord-008530-yni0poh9	26	12	chemokines	chemokine	NNS
cord-008530-yni0poh9	26	13	and	and	CC
cord-008530-yni0poh9	26	14	their	-PRON-	PRP$
cord-008530-yni0poh9	26	15	receptors	receptor	NNS
cord-008530-yni0poh9	26	16	in	in	IN
cord-008530-yni0poh9	26	17	viral	viral	JJ
cord-008530-yni0poh9	26	18	infection	infection	NN
cord-008530-yni0poh9	26	19	became	become	VBD
cord-008530-yni0poh9	26	20	apparent	apparent	JJ
cord-008530-yni0poh9	26	21	with	with	IN
cord-008530-yni0poh9	26	22	the	the	DT
cord-008530-yni0poh9	26	23	demonstration	demonstration	NN
cord-008530-yni0poh9	26	24	that	that	IN
cord-008530-yni0poh9	26	25	certain	certain	JJ
cord-008530-yni0poh9	26	26	classes	class	NNS
cord-008530-yni0poh9	26	27	of	of	IN
cord-008530-yni0poh9	26	28	chemokine	chemokine	NN
cord-008530-yni0poh9	26	29	receptors	receptor	NNS
cord-008530-yni0poh9	26	30	functioned	function	VBD
cord-008530-yni0poh9	26	31	as	as	IN
cord-008530-yni0poh9	26	32	essential	essential	JJ
cord-008530-yni0poh9	26	33	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	26	34	for	for	IN
cord-008530-yni0poh9	26	35	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	26	36	binding	binding	NN
cord-008530-yni0poh9	26	37	and	and	CC
cord-008530-yni0poh9	26	38	entry	entry	NN
cord-008530-yni0poh9	26	39	into	into	IN
cord-008530-yni0poh9	26	40	the	the	DT
cord-008530-yni0poh9	26	41	cell	cell	NN
cord-008530-yni0poh9	26	42	.	.	.
cord-008530-yni0poh9	27	1	Yet	yet	RB
cord-008530-yni0poh9	27	2	more	more	RBR
cord-008530-yni0poh9	27	3	recent	recent	JJ
cord-008530-yni0poh9	27	4	work	work	NN
cord-008530-yni0poh9	27	5	has	have	VBZ
cord-008530-yni0poh9	27	6	indicated	indicate	VBN
cord-008530-yni0poh9	27	7	that	that	IN
cord-008530-yni0poh9	27	8	the	the	DT
cord-008530-yni0poh9	27	9	genomes	genome	NNS
cord-008530-yni0poh9	27	10	of	of	IN
cord-008530-yni0poh9	27	11	some	some	DT
cord-008530-yni0poh9	27	12	large	large	JJ
cord-008530-yni0poh9	27	13	viruses	virus	NNS
cord-008530-yni0poh9	27	14	,	,	,
cord-008530-yni0poh9	27	15	belonging	belong	VBG
cord-008530-yni0poh9	27	16	to	to	IN
cord-008530-yni0poh9	27	17	the	the	DT
cord-008530-yni0poh9	27	18	herpesvirus	herpesvirus	NN
cord-008530-yni0poh9	27	19	and	and	CC
cord-008530-yni0poh9	27	20	poxvirus	poxvirus	NNP
cord-008530-yni0poh9	27	21	families	family	NNS
cord-008530-yni0poh9	27	22	,	,	,
cord-008530-yni0poh9	27	23	contain	contain	VBP
cord-008530-yni0poh9	27	24	homologs	homolog	NNS
cord-008530-yni0poh9	27	25	of	of	IN
cord-008530-yni0poh9	27	26	the	the	DT
cord-008530-yni0poh9	27	27	mammalian	mammalian	JJ
cord-008530-yni0poh9	27	28	chemokines	chemokine	NNS
cord-008530-yni0poh9	27	29	and	and	CC
cord-008530-yni0poh9	27	30	their	-PRON-	PRP$
cord-008530-yni0poh9	27	31	receptors	receptor	NNS
cord-008530-yni0poh9	27	32	.	.	.
cord-008530-yni0poh9	28	1	These	these	DT
cord-008530-yni0poh9	28	2	homologs	homolog	NNS
cord-008530-yni0poh9	28	3	may	may	MD
cord-008530-yni0poh9	28	4	function	function	VB
cord-008530-yni0poh9	28	5	to	to	TO
cord-008530-yni0poh9	28	6	modulate	modulate	VB
cord-008530-yni0poh9	28	7	local	local	JJ
cord-008530-yni0poh9	28	8	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	28	9	responses	response	NNS
cord-008530-yni0poh9	28	10	and	and	CC
cord-008530-yni0poh9	28	11	favor	favor	VB
cord-008530-yni0poh9	28	12	viral	viral	JJ
cord-008530-yni0poh9	28	13	survival	survival	NN
cord-008530-yni0poh9	28	14	and	and	CC
cord-008530-yni0poh9	28	15	spread	spread	NN
cord-008530-yni0poh9	28	16	.	.	.
cord-008530-yni0poh9	29	1	From	from	IN
cord-008530-yni0poh9	29	2	the	the	DT
cord-008530-yni0poh9	29	3	host	host	NN
cord-008530-yni0poh9	29	4	perspective	perspective	NN
cord-008530-yni0poh9	29	5	,	,	,
cord-008530-yni0poh9	29	6	accumulating	accumulate	VBG
cord-008530-yni0poh9	29	7	evidence	evidence	NN
cord-008530-yni0poh9	29	8	indicates	indicate	VBZ
cord-008530-yni0poh9	29	9	that	that	IN
cord-008530-yni0poh9	29	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	29	11	are	be	VBP
cord-008530-yni0poh9	29	12	plurifunctional	plurifunctional	JJ
cord-008530-yni0poh9	29	13	molecules	molecule	NNS
cord-008530-yni0poh9	29	14	that	that	WDT
cord-008530-yni0poh9	29	15	may	may	MD
cord-008530-yni0poh9	29	16	have	have	VB
cord-008530-yni0poh9	29	17	a	a	DT
cord-008530-yni0poh9	29	18	significant	significant	JJ
cord-008530-yni0poh9	29	19	impact	impact	NN
cord-008530-yni0poh9	29	20	on	on	IN
cord-008530-yni0poh9	29	21	the	the	DT
cord-008530-yni0poh9	29	22	CNS	CNS	NNP
cord-008530-yni0poh9	29	23	,	,	,
cord-008530-yni0poh9	29	24	regulating	regulate	VBG
cord-008530-yni0poh9	29	25	cellular	cellular	JJ
cord-008530-yni0poh9	29	26	communication	communication	NN
cord-008530-yni0poh9	29	27	in	in	IN
cord-008530-yni0poh9	29	28	the	the	DT
cord-008530-yni0poh9	29	29	developing	developing	NN
cord-008530-yni0poh9	29	30	and	and	CC
cord-008530-yni0poh9	29	31	the	the	DT
cord-008530-yni0poh9	29	32	normal	normal	JJ
cord-008530-yni0poh9	29	33	adult	adult	NN
cord-008530-yni0poh9	29	34	CNS	CNS	NNP
cord-008530-yni0poh9	29	35	(	(	-LRB-
cord-008530-yni0poh9	29	36	Asensio	Asensio	NNP
cord-008530-yni0poh9	29	37	and	and	CC
cord-008530-yni0poh9	29	38	Campbell	Campbell	NNP
cord-008530-yni0poh9	29	39	,	,	,
cord-008530-yni0poh9	29	40	1999	1999	CD
cord-008530-yni0poh9	29	41	)	)	-RRB-
cord-008530-yni0poh9	29	42	.	.	.
cord-008530-yni0poh9	30	1	Here	here	RB
cord-008530-yni0poh9	30	2	,	,	,
cord-008530-yni0poh9	30	3	we	-PRON-	PRP
cord-008530-yni0poh9	30	4	review	review	VBP
cord-008530-yni0poh9	30	5	the	the	DT
cord-008530-yni0poh9	30	6	subject	subject	NN
cord-008530-yni0poh9	30	7	of	of	IN
cord-008530-yni0poh9	30	8	chemokines	chemokine	NNS
cord-008530-yni0poh9	30	9	and	and	CC
cord-008530-yni0poh9	30	10	their	-PRON-	PRP$
cord-008530-yni0poh9	30	11	receptors	receptor	NNS
cord-008530-yni0poh9	30	12	in	in	IN
cord-008530-yni0poh9	30	13	the	the	DT
cord-008530-yni0poh9	30	14	evolution	evolution	NN
cord-008530-yni0poh9	30	15	of	of	IN
cord-008530-yni0poh9	30	16	viral	viral	JJ
cord-008530-yni0poh9	30	17	infectious	infectious	JJ
cord-008530-yni0poh9	30	18	diseases	disease	NNS
cord-008530-yni0poh9	30	19	of	of	IN
cord-008530-yni0poh9	30	20	the	the	DT
cord-008530-yni0poh9	30	21	CNS	CNS	NNP
cord-008530-yni0poh9	30	22	.	.	.
cord-008530-yni0poh9	31	1	As	as	IN
cord-008530-yni0poh9	31	2	a	a	DT
cord-008530-yni0poh9	31	3	prelude	prelude	NN
cord-008530-yni0poh9	31	4	to	to	IN
cord-008530-yni0poh9	31	5	the	the	DT
cord-008530-yni0poh9	31	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	31	7	.	.	.
cord-008530-yni0poh9	32	1	ATAC	ATAC	NNP
cord-008530-yni0poh9	32	2	,	,	,
cord-008530-yni0poh9	32	3	activation	activation	NN
cord-008530-yni0poh9	32	4	-	-	HYPH
cord-008530-yni0poh9	32	5	induced	induce	VBN
cord-008530-yni0poh9	32	6	chemokine	chemokine	NN
cord-008530-yni0poh9	32	7	-	-	HYPH
cord-008530-yni0poh9	32	8	related	relate	VBN
cord-008530-yni0poh9	32	9	molecule	molecule	NN
cord-008530-yni0poh9	32	10	exclusively	exclusively	RB
cord-008530-yni0poh9	32	11	expressed	express	VBN
cord-008530-yni0poh9	32	12	in	in	IN
cord-008530-yni0poh9	32	13	CD8	CD8	NNP
cord-008530-yni0poh9	32	14	÷	÷	NNP
cord-008530-yni0poh9	32	15	T	T	NNP
cord-008530-yni0poh9	32	16	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	33	1	;	;	:
cord-008530-yni0poh9	33	2	BCA-1	BCA-1	NNP
cord-008530-yni0poh9	33	3	/	/	SYM
cord-008530-yni0poh9	33	4	BLC	BLC	NNP
cord-008530-yni0poh9	33	5	,	,	,
cord-008530-yni0poh9	33	6	B	b	NN
cord-008530-yni0poh9	33	7	cell	cell	NN
cord-008530-yni0poh9	33	8	-	-	HYPH
cord-008530-yni0poh9	33	9	attracting	attract	VBG
cord-008530-yni0poh9	33	10	chemokine	chemokine	NN
cord-008530-yni0poh9	33	11	/	/	SYM
cord-008530-yni0poh9	33	12	B	b	NN
cord-008530-yni0poh9	33	13	-	-	HYPH
cord-008530-yni0poh9	33	14	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	33	15	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	33	16	;	;	:
cord-008530-yni0poh9	33	17	GRO	GRO	NNP
cord-008530-yni0poh9	33	18	,	,	,
cord-008530-yni0poh9	33	19	growth	growth	NN
cord-008530-yni0poh9	33	20	-	-	HYPH
cord-008530-yni0poh9	33	21	regulated	regulate	VBN
cord-008530-yni0poh9	33	22	oncogene	oncogene	NN
cord-008530-yni0poh9	33	23	;	;	:
cord-008530-yni0poh9	33	24	IL-8	IL-8	NNP
cord-008530-yni0poh9	33	25	,	,	,
cord-008530-yni0poh9	33	26	interleukin-8	interleukin-8	NNP
cord-008530-yni0poh9	33	27	;	;	:
cord-008530-yni0poh9	33	28	IP-10	IP-10	NNP
cord-008530-yni0poh9	33	29	,	,	,
cord-008530-yni0poh9	33	30	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	33	31	protein	protein	NN
cord-008530-yni0poh9	33	32	10	10	CD
cord-008530-yni0poh9	33	33	kD	kd	JJ
cord-008530-yni0poh9	33	34	;	;	:
cord-008530-yni0poh9	33	35	I	I	NNP
cord-008530-yni0poh9	33	36	-	-	HYPH
cord-008530-yni0poh9	33	37	TAC	TAC	NNP
cord-008530-yni0poh9	33	38	,	,	,
cord-008530-yni0poh9	33	39	interferon	interferon	NN
cord-008530-yni0poh9	33	40	-	-	HYPH
cord-008530-yni0poh9	33	41	inducible	inducible	JJ
cord-008530-yni0poh9	33	42	T	T	NNP
cord-008530-yni0poh9	33	43	cell	cell	NN
cord-008530-yni0poh9	33	44	alpha	alpha	NN
cord-008530-yni0poh9	33	45	-	-	HYPH
cord-008530-yni0poh9	33	46	chemoattractant	chemoattractant	JJ
cord-008530-yni0poh9	33	47	;	;	:
cord-008530-yni0poh9	33	48	LIX	LIX	NNP
cord-008530-yni0poh9	33	49	,	,	,
cord-008530-yni0poh9	33	50	LPS	LPS	NNP
cord-008530-yni0poh9	33	51	-	-	HYPH
cord-008530-yni0poh9	33	52	induced	induce	VBN
cord-008530-yni0poh9	33	53	CXC	CXC	NNP
cord-008530-yni0poh9	33	54	chemokine	chemokine	NN
cord-008530-yni0poh9	33	55	;	;	:
cord-008530-yni0poh9	33	56	MCP	MCP	NNP
cord-008530-yni0poh9	33	57	,	,	,
cord-008530-yni0poh9	33	58	monocyte	monocyte	NNP
cord-008530-yni0poh9	33	59	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	33	60	protein	protein	NN
cord-008530-yni0poh9	33	61	;	;	:
cord-008530-yni0poh9	33	62	Mig	Mig	NNP
cord-008530-yni0poh9	33	63	,	,	,
cord-008530-yni0poh9	33	64	monokine	monokine	NN
cord-008530-yni0poh9	33	65	induced	induce	VBN
cord-008530-yni0poh9	33	66	by	by	IN
cord-008530-yni0poh9	33	67	interferon	interferon	NN
cord-008530-yni0poh9	33	68	-	-	HYPH
cord-008530-yni0poh9	33	69	gamma	gamma	NN
cord-008530-yni0poh9	33	70	;	;	:
cord-008530-yni0poh9	33	71	MIP	MIP	NNP
cord-008530-yni0poh9	33	72	,	,	,
cord-008530-yni0poh9	33	73	macrophage	macrophage	NN
cord-008530-yni0poh9	33	74	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	33	75	protein	protein	NN
cord-008530-yni0poh9	33	76	;	;	.
cord-008530-yni0poh9	34	1	MRP-1	MRP-1	NNP
cord-008530-yni0poh9	34	2	,	,	,
cord-008530-yni0poh9	34	3	MIPrelated	miprelated	JJ
cord-008530-yni0poh9	34	4	protein	protein	NN
cord-008530-yni0poh9	34	5	1	1	CD
cord-008530-yni0poh9	34	6	;	;	:
cord-008530-yni0poh9	34	7	PBP	PBP	NNP
cord-008530-yni0poh9	34	8	,	,	,
cord-008530-yni0poh9	34	9	platelet	platelet	NN
cord-008530-yni0poh9	34	10	basic	basic	JJ
cord-008530-yni0poh9	34	11	protein	protein	NN
cord-008530-yni0poh9	34	12	;	;	:
cord-008530-yni0poh9	34	13	PF4	pf4	JJ
cord-008530-yni0poh9	34	14	,	,	,
cord-008530-yni0poh9	34	15	platelet	platelet	NN
cord-008530-yni0poh9	34	16	factor	factor	NN
cord-008530-yni0poh9	34	17	4	4	CD
cord-008530-yni0poh9	34	18	;	;	:
cord-008530-yni0poh9	34	19	RANTES	RANTES	NNP
cord-008530-yni0poh9	34	20	,	,	,
cord-008530-yni0poh9	34	21	regulated	regulate	VBN
cord-008530-yni0poh9	34	22	on	on	IN
cord-008530-yni0poh9	34	23	activation	activation	NN
cord-008530-yni0poh9	34	24	-	-	HYPH
cord-008530-yni0poh9	34	25	normal	normal	JJ
cord-008530-yni0poh9	34	26	T	T	NNP
cord-008530-yni0poh9	34	27	cell	cell	NN
cord-008530-yni0poh9	34	28	expressed	express	VBD
cord-008530-yni0poh9	34	29	and	and	CC
cord-008530-yni0poh9	34	30	secreted	secrete	VBN
cord-008530-yni0poh9	34	31	;	;	:
cord-008530-yni0poh9	34	32	SDF-1	sdf-1	NN
cord-008530-yni0poh9	34	33	,	,	,
cord-008530-yni0poh9	34	34	stromal	stromal	JJ
cord-008530-yni0poh9	34	35	cell	cell	NN
cord-008530-yni0poh9	34	36	-	-	HYPH
cord-008530-yni0poh9	34	37	derived	derive	VBN
cord-008530-yni0poh9	34	38	factor-1	factor-1	NNP
cord-008530-yni0poh9	34	39	;	;	:
cord-008530-yni0poh9	34	40	SLC	SLC	NNP
cord-008530-yni0poh9	34	41	,	,	,
cord-008530-yni0poh9	34	42	secondary	secondary	JJ
cord-008530-yni0poh9	34	43	lymphoid	lymphoid	JJ
cord-008530-yni0poh9	34	44	tissue	tissue	NN
cord-008530-yni0poh9	34	45	chemokine	chemokine	NN
cord-008530-yni0poh9	34	46	;	;	:
cord-008530-yni0poh9	34	47	chr	chr	NNP
cord-008530-yni0poh9	34	48	.	.	NNP
cord-008530-yni0poh9	34	49	,	,	,
cord-008530-yni0poh9	34	50	chromosome	chromosome	NN
cord-008530-yni0poh9	34	51	.	.	.
cord-008530-yni0poh9	35	1	main	main	JJ
cord-008530-yni0poh9	35	2	subject	subject	NN
cord-008530-yni0poh9	35	3	of	of	IN
cord-008530-yni0poh9	35	4	this	this	DT
cord-008530-yni0poh9	35	5	chapter	chapter	NN
cord-008530-yni0poh9	35	6	,	,	,
cord-008530-yni0poh9	35	7	our	-PRON-	PRP$
cord-008530-yni0poh9	35	8	discussion	discussion	NN
cord-008530-yni0poh9	35	9	initially	initially	RB
cord-008530-yni0poh9	35	10	will	will	MD
cord-008530-yni0poh9	35	11	provide	provide	VB
cord-008530-yni0poh9	35	12	the	the	DT
cord-008530-yni0poh9	35	13	reader	reader	NN
cord-008530-yni0poh9	35	14	with	with	IN
cord-008530-yni0poh9	35	15	a	a	DT
cord-008530-yni0poh9	35	16	general	general	JJ
cord-008530-yni0poh9	35	17	background	background	NN
cord-008530-yni0poh9	35	18	to	to	IN
cord-008530-yni0poh9	35	19	the	the	DT
cord-008530-yni0poh9	35	20	rapidly	rapidly	RB
cord-008530-yni0poh9	35	21	expanding	expand	VBG
cord-008530-yni0poh9	35	22	area	area	NN
cord-008530-yni0poh9	35	23	of	of	IN
cord-008530-yni0poh9	35	24	chemokines	chemokine	NNS
cord-008530-yni0poh9	35	25	and	and	CC
cord-008530-yni0poh9	35	26	their	-PRON-	PRP$
cord-008530-yni0poh9	35	27	receptors	receptor	NNS
cord-008530-yni0poh9	35	28	and	and	CC
cord-008530-yni0poh9	35	29	the	the	DT
cord-008530-yni0poh9	35	30	expression	expression	NN
cord-008530-yni0poh9	35	31	of	of	IN
cord-008530-yni0poh9	35	32	these	these	DT
cord-008530-yni0poh9	35	33	molecules	molecule	NNS
cord-008530-yni0poh9	35	34	in	in	IN
cord-008530-yni0poh9	35	35	the	the	DT
cord-008530-yni0poh9	35	36	CNS	CNS	NNP
cord-008530-yni0poh9	35	37	.	.	.
cord-008530-yni0poh9	36	1	The	the	DT
cord-008530-yni0poh9	36	2	chemokines	chemokine	NNS
cord-008530-yni0poh9	36	3	are	be	VBP
cord-008530-yni0poh9	36	4	currently	currently	RB
cord-008530-yni0poh9	36	5	divided	divide	VBN
cord-008530-yni0poh9	36	6	into	into	IN
cord-008530-yni0poh9	36	7	4	4	CD
cord-008530-yni0poh9	36	8	families	family	NNS
cord-008530-yni0poh9	36	9	(	(	-LRB-
cord-008530-yni0poh9	36	10	Fig	Fig	NNP
cord-008530-yni0poh9	36	11	.	.	NNP
cord-008530-yni0poh9	36	12	1	1	CD
cord-008530-yni0poh9	36	13	)	)	-RRB-
cord-008530-yni0poh9	36	14	:	:	:
cord-008530-yni0poh9	36	15	the	the	DT
cord-008530-yni0poh9	36	16	CXC	CXC	NNP
cord-008530-yni0poh9	36	17	or	or	CC
cord-008530-yni0poh9	36	18	~	~	NFP
cord-008530-yni0poh9	36	19	family	family	NN
cord-008530-yni0poh9	36	20	;	;	:
cord-008530-yni0poh9	36	21	the	the	DT
cord-008530-yni0poh9	36	22	CC	CC	NNP
cord-008530-yni0poh9	36	23	or	or	CC
cord-008530-yni0poh9	36	24	~	~	NFP
cord-008530-yni0poh9	36	25	family	family	NN
cord-008530-yni0poh9	36	26	;	;	:
cord-008530-yni0poh9	36	27	the	the	DT
cord-008530-yni0poh9	36	28	C	C	NNP
cord-008530-yni0poh9	36	29	or	or	CC
cord-008530-yni0poh9	36	30	7	7	CD
cord-008530-yni0poh9	36	31	family	family	NN
cord-008530-yni0poh9	36	32	;	;	:
cord-008530-yni0poh9	36	33	and	and	CC
cord-008530-yni0poh9	36	34	the	the	DT
cord-008530-yni0poh9	36	35	CX3C	CX3C	NNS
cord-008530-yni0poh9	36	36	or	or	CC
cord-008530-yni0poh9	36	37	5	5	CD
cord-008530-yni0poh9	36	38	family	family	NN
cord-008530-yni0poh9	37	1	(	(	-LRB-
cord-008530-yni0poh9	37	2	Zlotnik	Zlotnik	NNP
cord-008530-yni0poh9	37	3	et	et	NNP
cord-008530-yni0poh9	37	4	al	al	NNP
cord-008530-yni0poh9	37	5	.	.	NNP
cord-008530-yni0poh9	37	6	,	,	,
cord-008530-yni0poh9	37	7	1999	1999	CD
cord-008530-yni0poh9	37	8	)	)	-RRB-
cord-008530-yni0poh9	37	9	.	.	.
cord-008530-yni0poh9	38	1	In	in	IN
cord-008530-yni0poh9	38	2	general	general	JJ
cord-008530-yni0poh9	38	3	,	,	,
cord-008530-yni0poh9	38	4	within	within	IN
cord-008530-yni0poh9	38	5	each	each	DT
cord-008530-yni0poh9	38	6	chemokine	chemokine	NN
cord-008530-yni0poh9	38	7	subfamily	subfamily	NN
cord-008530-yni0poh9	38	8	,	,	,
cord-008530-yni0poh9	38	9	the	the	DT
cord-008530-yni0poh9	38	10	individual	individual	JJ
cord-008530-yni0poh9	38	11	members	member	NNS
cord-008530-yni0poh9	38	12	show	show	VBP
cord-008530-yni0poh9	38	13	considerable	considerable	JJ
cord-008530-yni0poh9	38	14	homology	homology	NN
cord-008530-yni0poh9	38	15	in	in	IN
cord-008530-yni0poh9	38	16	their	-PRON-	PRP$
cord-008530-yni0poh9	38	17	130	130	CD
cord-008530-yni0poh9	38	18	VAL]~RIE	VAL]~RIE	NNP
cord-008530-yni0poh9	38	19	C.	C.	NNP
cord-008530-yni0poh9	38	20	ASENSIO	ASENSIO	NNP
cord-008530-yni0poh9	38	21	AND	and	CC
cord-008530-yni0poh9	38	22	IAIN	IAIN	NNP
cord-008530-yni0poh9	38	23	L.	L.	NNP
cord-008530-yni0poh9	38	24	CAMPBELL	CAMPBELL	NNP
cord-008530-yni0poh9	38	25	amino	amino	NN
cord-008530-yni0poh9	38	26	acid	acid	NN
cord-008530-yni0poh9	38	27	sequence	sequence	NN
cord-008530-yni0poh9	38	28	and	and	CC
cord-008530-yni0poh9	38	29	often	often	RB
cord-008530-yni0poh9	38	30	possess	possess	VBP
cord-008530-yni0poh9	38	31	overlapping	overlap	VBG
cord-008530-yni0poh9	38	32	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	38	33	specificity	specificity	NN
cord-008530-yni0poh9	38	34	.	.	.
cord-008530-yni0poh9	39	1	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	39	2	share	share	VBP
cord-008530-yni0poh9	39	3	a	a	DT
cord-008530-yni0poh9	39	4	common	common	JJ
cord-008530-yni0poh9	39	5	three	three	CD
cord-008530-yni0poh9	39	6	-	-	HYPH
cord-008530-yni0poh9	39	7	dimensional	dimensional	JJ
cord-008530-yni0poh9	39	8	structure	structure	NN
cord-008530-yni0poh9	39	9	including	include	VBG
cord-008530-yni0poh9	39	10	an	an	DT
cord-008530-yni0poh9	39	11	NH2-terminal	nh2-terminal	JJ
cord-008530-yni0poh9	39	12	loop	loop	NN
cord-008530-yni0poh9	39	13	and	and	CC
cord-008530-yni0poh9	39	14	three	three	CD
cord-008530-yni0poh9	39	15	antiparallel	antiparallel	NN
cord-008530-yni0poh9	39	16	~	~	NFP
cord-008530-yni0poh9	39	17	sheets	sheet	NNS
cord-008530-yni0poh9	39	18	that	that	WDT
cord-008530-yni0poh9	39	19	are	be	VBP
cord-008530-yni0poh9	39	20	followed	follow	VBN
cord-008530-yni0poh9	39	21	by	by	IN
cord-008530-yni0poh9	39	22	a	a	DT
cord-008530-yni0poh9	39	23	C	C	NNP
cord-008530-yni0poh9	39	24	-	-	HYPH
cord-008530-yni0poh9	39	25	terminal	terminal	NN
cord-008530-yni0poh9	39	26	a	a	DT
cord-008530-yni0poh9	39	27	helix	helix	NN
cord-008530-yni0poh9	39	28	.	.	.
cord-008530-yni0poh9	40	1	The	the	DT
cord-008530-yni0poh9	40	2	amino	amino	NN
cord-008530-yni0poh9	40	3	acid	acid	NN
cord-008530-yni0poh9	40	4	backbone	backbone	NN
cord-008530-yni0poh9	40	5	of	of	IN
cord-008530-yni0poh9	40	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	40	7	belonging	belong	VBG
cord-008530-yni0poh9	40	8	to	to	IN
cord-008530-yni0poh9	40	9	the	the	DT
cord-008530-yni0poh9	40	10	CC	CC	NNP
cord-008530-yni0poh9	40	11	,	,	,
cord-008530-yni0poh9	40	12	CXC	CXC	NNP
cord-008530-yni0poh9	40	13	,	,	,
cord-008530-yni0poh9	40	14	and	and	CC
cord-008530-yni0poh9	40	15	CX3C	CX3C	NNS
cord-008530-yni0poh9	40	16	families	family	NNS
cord-008530-yni0poh9	40	17	contains	contain	VBZ
cord-008530-yni0poh9	40	18	four	four	CD
cord-008530-yni0poh9	40	19	conserved	conserved	JJ
cord-008530-yni0poh9	40	20	cysteines	cysteine	NNS
cord-008530-yni0poh9	40	21	,	,	,
cord-008530-yni0poh9	40	22	while	while	IN
cord-008530-yni0poh9	40	23	the	the	DT
cord-008530-yni0poh9	40	24	C	C	NNP
cord-008530-yni0poh9	40	25	family	family	NN
cord-008530-yni0poh9	40	26	chemokine	chemokine	NN
cord-008530-yni0poh9	40	27	,	,	,
cord-008530-yni0poh9	40	28	lymphotactin	lymphotactin	NNP
cord-008530-yni0poh9	40	29	,	,	,
cord-008530-yni0poh9	40	30	contains	contain	VBZ
cord-008530-yni0poh9	40	31	only	only	RB
cord-008530-yni0poh9	40	32	two	two	CD
cord-008530-yni0poh9	40	33	cysteines	cysteine	NNS
cord-008530-yni0poh9	40	34	,	,	,
cord-008530-yni0poh9	40	35	which	which	WDT
cord-008530-yni0poh9	40	36	correspond	correspond	VBP
cord-008530-yni0poh9	40	37	to	to	IN
cord-008530-yni0poh9	40	38	the	the	DT
cord-008530-yni0poh9	40	39	first	first	JJ
cord-008530-yni0poh9	40	40	and	and	CC
cord-008530-yni0poh9	40	41	third	third	JJ
cord-008530-yni0poh9	40	42	cysteines	cysteine	NNS
cord-008530-yni0poh9	40	43	in	in	IN
cord-008530-yni0poh9	40	44	the	the	DT
cord-008530-yni0poh9	40	45	other	other	JJ
cord-008530-yni0poh9	40	46	groups	group	NNS
cord-008530-yni0poh9	40	47	.	.	.
cord-008530-yni0poh9	41	1	Chemokines	chemokine	NNS
cord-008530-yni0poh9	41	2	can	can	MD
cord-008530-yni0poh9	41	3	be	be	VB
cord-008530-yni0poh9	41	4	produced	produce	VBN
cord-008530-yni0poh9	41	5	by	by	IN
cord-008530-yni0poh9	41	6	a	a	DT
cord-008530-yni0poh9	41	7	variety	variety	NN
cord-008530-yni0poh9	41	8	of	of	IN
cord-008530-yni0poh9	41	9	immune	immune	JJ
cord-008530-yni0poh9	41	10	cells	cell	NNS
cord-008530-yni0poh9	41	11	such	such	JJ
cord-008530-yni0poh9	41	12	as	as	IN
cord-008530-yni0poh9	41	13	T	T	NNP
cord-008530-yni0poh9	41	14	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	41	15	,	,	,
cord-008530-yni0poh9	41	16	macrophages	macrophage	NNS
cord-008530-yni0poh9	41	17	,	,	,
cord-008530-yni0poh9	41	18	and	and	CC
cord-008530-yni0poh9	41	19	natural	natural	JJ
cord-008530-yni0poh9	41	20	killer	killer	NN
cord-008530-yni0poh9	41	21	(	(	-LRB-
cord-008530-yni0poh9	41	22	NK	NK	NNP
cord-008530-yni0poh9	41	23	)	)	-RRB-
cord-008530-yni0poh9	41	24	cells	cell	NNS
cord-008530-yni0poh9	41	25	,	,	,
cord-008530-yni0poh9	41	26	but	but	CC
cord-008530-yni0poh9	41	27	also	also	RB
cord-008530-yni0poh9	41	28	by	by	IN
cord-008530-yni0poh9	41	29	organ	organ	NN
cord-008530-yni0poh9	41	30	-	-	HYPH
cord-008530-yni0poh9	41	31	specific	specific	JJ
cord-008530-yni0poh9	41	32	cell	cell	NN
cord-008530-yni0poh9	41	33	types	type	NNS
cord-008530-yni0poh9	41	34	such	such	JJ
cord-008530-yni0poh9	41	35	as	as	IN
cord-008530-yni0poh9	41	36	resident	resident	JJ
cord-008530-yni0poh9	41	37	glial	glial	JJ
cord-008530-yni0poh9	41	38	cells	cell	NNS
cord-008530-yni0poh9	41	39	in	in	IN
cord-008530-yni0poh9	41	40	the	the	DT
cord-008530-yni0poh9	41	41	CNS	CNS	NNP
cord-008530-yni0poh9	41	42	(	(	-LRB-
cord-008530-yni0poh9	41	43	see	see	VB
cord-008530-yni0poh9	41	44	the	the	DT
cord-008530-yni0poh9	41	45	discussion	discussion	NN
cord-008530-yni0poh9	41	46	below	below	RB
cord-008530-yni0poh9	41	47	)	)	-RRB-
cord-008530-yni0poh9	41	48	.	.	.
cord-008530-yni0poh9	42	1	Depending	depend	VBG
cord-008530-yni0poh9	42	2	on	on	IN
cord-008530-yni0poh9	42	3	the	the	DT
cord-008530-yni0poh9	42	4	chemokine	chemokine	NN
cord-008530-yni0poh9	42	5	and	and	CC
cord-008530-yni0poh9	42	6	its	-PRON-	PRP$
cord-008530-yni0poh9	42	7	cellular	cellular	JJ
cord-008530-yni0poh9	42	8	source	source	NN
cord-008530-yni0poh9	42	9	,	,	,
cord-008530-yni0poh9	42	10	the	the	DT
cord-008530-yni0poh9	42	11	expression	expression	NN
cord-008530-yni0poh9	42	12	of	of	IN
cord-008530-yni0poh9	42	13	chemokines	chemokine	NNS
cord-008530-yni0poh9	42	14	may	may	MD
cord-008530-yni0poh9	42	15	be	be	VB
cord-008530-yni0poh9	42	16	constitutive	constitutive	JJ
cord-008530-yni0poh9	42	17	or	or	CC
cord-008530-yni0poh9	42	18	inducible	inducible	JJ
cord-008530-yni0poh9	42	19	,	,	,
cord-008530-yni0poh9	42	20	and	and	CC
cord-008530-yni0poh9	42	21	a	a	DT
cord-008530-yni0poh9	42	22	new	new	JJ
cord-008530-yni0poh9	42	23	classification	classification	NN
cord-008530-yni0poh9	42	24	of	of	IN
cord-008530-yni0poh9	42	25	chemokines	chemokine	NNS
cord-008530-yni0poh9	42	26	,	,	,
cord-008530-yni0poh9	42	27	defined	define	VBN
cord-008530-yni0poh9	42	28	according	accord	VBG
cord-008530-yni0poh9	42	29	to	to	IN
cord-008530-yni0poh9	42	30	their	-PRON-	PRP$
cord-008530-yni0poh9	42	31	expression	expression	NN
cord-008530-yni0poh9	42	32	pattern	pattern	NN
cord-008530-yni0poh9	42	33	,	,	,
cord-008530-yni0poh9	42	34	has	have	VBZ
cord-008530-yni0poh9	42	35	been	be	VBN
cord-008530-yni0poh9	42	36	proposed	propose	VBN
cord-008530-yni0poh9	42	37	(	(	-LRB-
cord-008530-yni0poh9	42	38	Mantovani	Mantovani	NNP
cord-008530-yni0poh9	42	39	,	,	,
cord-008530-yni0poh9	42	40	1999a	1999a	CD
cord-008530-yni0poh9	42	41	;	;	:
cord-008530-yni0poh9	42	42	Sallusto	Sallusto	NNP
cord-008530-yni0poh9	42	43	et	et	FW
cord-008530-yni0poh9	42	44	al	al	NNP
cord-008530-yni0poh9	42	45	.	.	NNP
cord-008530-yni0poh9	42	46	,	,	,
cord-008530-yni0poh9	42	47	1999a	1999a	CD
cord-008530-yni0poh9	42	48	)	)	-RRB-
cord-008530-yni0poh9	42	49	.	.	.
cord-008530-yni0poh9	43	1	The	the	DT
cord-008530-yni0poh9	43	2	regulation	regulation	NN
cord-008530-yni0poh9	43	3	of	of	IN
cord-008530-yni0poh9	43	4	chemokine	chemokine	NN
cord-008530-yni0poh9	43	5	expression	expression	NN
cord-008530-yni0poh9	43	6	can	can	MD
cord-008530-yni0poh9	43	7	be	be	VB
cord-008530-yni0poh9	43	8	mediated	mediate	VBN
cord-008530-yni0poh9	43	9	by	by	IN
cord-008530-yni0poh9	43	10	soluble	soluble	JJ
cord-008530-yni0poh9	43	11	factors	factor	NNS
cord-008530-yni0poh9	43	12	such	such	JJ
cord-008530-yni0poh9	43	13	as	as	IN
cord-008530-yni0poh9	43	14	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	43	15	cytokines	cytokine	NNS
cord-008530-yni0poh9	43	16	,	,	,
cord-008530-yni0poh9	43	17	e.g.	e.g.	RB
cord-008530-yni0poh9	43	18	,	,	,
cord-008530-yni0poh9	43	19	interleukin	interleukin	FW
cord-008530-yni0poh9	43	20	(	(	-LRB-
cord-008530-yni0poh9	43	21	IL)-I	IL)-I	NNP
cord-008530-yni0poh9	43	22	,	,	,
cord-008530-yni0poh9	43	23	tumor	tumor	NN
cord-008530-yni0poh9	43	24	necrosis	necrosis	NN
cord-008530-yni0poh9	43	25	factor	factor	NN
cord-008530-yni0poh9	43	26	(	(	-LRB-
cord-008530-yni0poh9	43	27	TNF)-a	TNF)-a	NNP
cord-008530-yni0poh9	43	28	,	,	,
cord-008530-yni0poh9	43	29	interferon	interferon	NN
cord-008530-yni0poh9	43	30	(	(	-LRB-
cord-008530-yni0poh9	43	31	IFN)-7	ifn)-7	NN
cord-008530-yni0poh9	43	32	,	,	,
cord-008530-yni0poh9	43	33	as	as	RB
cord-008530-yni0poh9	43	34	well	well	RB
cord-008530-yni0poh9	43	35	as	as	IN
cord-008530-yni0poh9	43	36	by	by	IN
cord-008530-yni0poh9	43	37	microbial	microbial	JJ
cord-008530-yni0poh9	43	38	products	product	NNS
cord-008530-yni0poh9	43	39	,	,	,
cord-008530-yni0poh9	43	40	e.g.	e.g.	RB
cord-008530-yni0poh9	43	41	,	,	,
cord-008530-yni0poh9	43	42	bacterial	bacterial	JJ
cord-008530-yni0poh9	43	43	lipopolysaccharide	lipopolysaccharide	NN
cord-008530-yni0poh9	43	44	(	(	-LRB-
cord-008530-yni0poh9	43	45	LPS	LPS	NNP
cord-008530-yni0poh9	43	46	)	)	-RRB-
cord-008530-yni0poh9	43	47	or	or	CC
cord-008530-yni0poh9	43	48	HIV	HIV	NNP
cord-008530-yni0poh9	43	49	coat	coat	NN
cord-008530-yni0poh9	43	50	protein	protein	NN
cord-008530-yni0poh9	43	51	gp120	gp120	NNP
cord-008530-yni0poh9	43	52	(	(	-LRB-
cord-008530-yni0poh9	43	53	Baggiolini	Baggiolini	NNP
cord-008530-yni0poh9	43	54	,	,	,
cord-008530-yni0poh9	43	55	1998	1998	CD
cord-008530-yni0poh9	43	56	;	;	:
cord-008530-yni0poh9	44	1	Baggiolini	Baggiolini	NNP
cord-008530-yni0poh9	44	2	et	et	NNP
cord-008530-yni0poh9	44	3	al	al	NNP
cord-008530-yni0poh9	44	4	.	.	NNP
cord-008530-yni0poh9	44	5	,	,	,
cord-008530-yni0poh9	44	6	1997	1997	CD
cord-008530-yni0poh9	44	7	;	;	:
cord-008530-yni0poh9	44	8	Premack	Premack	NNP
cord-008530-yni0poh9	44	9	and	and	CC
cord-008530-yni0poh9	44	10	Schall	Schall	NNP
cord-008530-yni0poh9	44	11	,	,	,
cord-008530-yni0poh9	44	12	1996	1996	CD
cord-008530-yni0poh9	44	13	;	;	:
cord-008530-yni0poh9	44	14	Strieter	Strieter	NNP
cord-008530-yni0poh9	44	15	et	et	NNP
cord-008530-yni0poh9	44	16	al	al	NNP
cord-008530-yni0poh9	44	17	.	.	NNP
cord-008530-yni0poh9	44	18	,	,	,
cord-008530-yni0poh9	44	19	1996	1996	CD
cord-008530-yni0poh9	44	20	)	)	-RRB-
cord-008530-yni0poh9	44	21	.	.	.
cord-008530-yni0poh9	45	1	In	in	IN
cord-008530-yni0poh9	45	2	contrast	contrast	NN
cord-008530-yni0poh9	45	3	,	,	,
cord-008530-yni0poh9	45	4	counterregulatory	counterregulatory	NN
cord-008530-yni0poh9	45	5	cytokines	cytokine	NNS
cord-008530-yni0poh9	45	6	can	can	MD
cord-008530-yni0poh9	45	7	downregulate	downregulate	VB
cord-008530-yni0poh9	45	8	the	the	DT
cord-008530-yni0poh9	45	9	production	production	NN
cord-008530-yni0poh9	45	10	of	of	IN
cord-008530-yni0poh9	45	11	chemokines	chemokine	NNS
cord-008530-yni0poh9	45	12	.	.	.
cord-008530-yni0poh9	46	1	For	for	IN
cord-008530-yni0poh9	46	2	example	example	NN
cord-008530-yni0poh9	46	3	,	,	,
cord-008530-yni0poh9	46	4	IL-10	IL-10	NNP
cord-008530-yni0poh9	46	5	and	and	CC
cord-008530-yni0poh9	46	6	transforming	transform	VBG
cord-008530-yni0poh9	46	7	growth	growth	NN
cord-008530-yni0poh9	46	8	factor	factor	NN
cord-008530-yni0poh9	46	9	(	(	-LRB-
cord-008530-yni0poh9	46	10	TGF)-~	tgf)-~	PRP
cord-008530-yni0poh9	46	11	have	have	VBP
cord-008530-yni0poh9	46	12	been	be	VBN
cord-008530-yni0poh9	46	13	shown	show	VBN
cord-008530-yni0poh9	46	14	to	to	TO
cord-008530-yni0poh9	46	15	inhibit	inhibit	VB
cord-008530-yni0poh9	46	16	LPS	LPS	NNP
cord-008530-yni0poh9	46	17	-	-	HYPH
cord-008530-yni0poh9	46	18	induced	induce	VBN
cord-008530-yni0poh9	46	19	microglial	microglial	JJ
cord-008530-yni0poh9	46	20	cell	cell	NN
cord-008530-yni0poh9	46	21	RANTES	RANTES	NNP
cord-008530-yni0poh9	46	22	mRNA	mRNA	NNP
cord-008530-yni0poh9	46	23	expression	expression	NN
cord-008530-yni0poh9	46	24	and	and	CC
cord-008530-yni0poh9	46	25	protein	protein	NN
cord-008530-yni0poh9	46	26	release	release	NN
cord-008530-yni0poh9	46	27	(	(	-LRB-
cord-008530-yni0poh9	46	28	Hu	Hu	NNP
cord-008530-yni0poh9	46	29	et	et	FW
cord-008530-yni0poh9	46	30	al	al	NNP
cord-008530-yni0poh9	46	31	.	.	NNP
cord-008530-yni0poh9	46	32	,	,	,
cord-008530-yni0poh9	46	33	1999	1999	CD
cord-008530-yni0poh9	46	34	)	)	-RRB-
cord-008530-yni0poh9	46	35	.	.	.
cord-008530-yni0poh9	47	1	The	the	DT
cord-008530-yni0poh9	47	2	glucocorticoid	glucocorticoid	NN
cord-008530-yni0poh9	47	3	dexamethasone	dexamethasone	NN
cord-008530-yni0poh9	47	4	is	be	VBZ
cord-008530-yni0poh9	47	5	also	also	RB
cord-008530-yni0poh9	47	6	a	a	DT
cord-008530-yni0poh9	47	7	particularly	particularly	RB
cord-008530-yni0poh9	47	8	potent	potent	JJ
cord-008530-yni0poh9	47	9	inhibitor	inhibitor	NN
cord-008530-yni0poh9	47	10	for	for	IN
cord-008530-yni0poh9	47	11	CC	CC	NNP
cord-008530-yni0poh9	47	12	and	and	CC
cord-008530-yni0poh9	47	13	CXC	CXC	NNP
cord-008530-yni0poh9	47	14	chemokine	chemokine	NN
cord-008530-yni0poh9	47	15	production	production	NN
cord-008530-yni0poh9	48	1	(	(	-LRB-
cord-008530-yni0poh9	48	2	Tobler	Tobler	NNP
cord-008530-yni0poh9	48	3	et	et	NNP
cord-008530-yni0poh9	48	4	al	al	NNP
cord-008530-yni0poh9	48	5	.	.	.
cord-008530-yni0poh9	49	1	,	,	,
cord-008530-yni0poh9	49	2	1992	1992	CD
cord-008530-yni0poh9	49	3	;	;	:
cord-008530-yni0poh9	49	4	Villiger	Villiger	NNP
cord-008530-yni0poh9	49	5	et	et	NNP
cord-008530-yni0poh9	49	6	al	al	NNP
cord-008530-yni0poh9	49	7	.	.	NNP
cord-008530-yni0poh9	49	8	,	,	,
cord-008530-yni0poh9	49	9	1992	1992	CD
cord-008530-yni0poh9	49	10	)	)	-RRB-
cord-008530-yni0poh9	49	11	.	.	.
cord-008530-yni0poh9	50	1	The	the	DT
cord-008530-yni0poh9	50	2	biological	biological	JJ
cord-008530-yni0poh9	50	3	effects	effect	NNS
cord-008530-yni0poh9	50	4	of	of	IN
cord-008530-yni0poh9	50	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	50	6	are	be	VBP
cord-008530-yni0poh9	50	7	mediated	mediate	VBN
cord-008530-yni0poh9	50	8	via	via	IN
cord-008530-yni0poh9	50	9	their	-PRON-	PRP$
cord-008530-yni0poh9	50	10	interaction	interaction	NN
cord-008530-yni0poh9	50	11	with	with	IN
cord-008530-yni0poh9	50	12	receptors	receptor	NNS
cord-008530-yni0poh9	50	13	belonging	belong	VBG
cord-008530-yni0poh9	50	14	to	to	IN
cord-008530-yni0poh9	50	15	the	the	DT
cord-008530-yni0poh9	50	16	family	family	NN
cord-008530-yni0poh9	50	17	of	of	IN
cord-008530-yni0poh9	50	18	seven	seven	CD
cord-008530-yni0poh9	50	19	transmembrane	transmembrane	NNP
cord-008530-yni0poh9	50	20	(	(	-LRB-
cord-008530-yni0poh9	50	21	7TM)-spanning	7TM)-spanning	NNP
cord-008530-yni0poh9	50	22	,	,	,
cord-008530-yni0poh9	50	23	G	g	NN
cord-008530-yni0poh9	50	24	-	-	HYPH
cord-008530-yni0poh9	50	25	protein	protein	NN
cord-008530-yni0poh9	50	26	-	-	HYPH
cord-008530-yni0poh9	50	27	coupled	couple	VBN
cord-008530-yni0poh9	50	28	receptors	receptor	NNS
cord-008530-yni0poh9	50	29	(	(	-LRB-
cord-008530-yni0poh9	50	30	GPCRs	GPCRs	NNP
cord-008530-yni0poh9	50	31	)	)	-RRB-
cord-008530-yni0poh9	50	32	.	.	.
cord-008530-yni0poh9	51	1	All	all	DT
cord-008530-yni0poh9	51	2	chemokine	chemokine	NN
cord-008530-yni0poh9	51	3	receptors	receptor	NNS
cord-008530-yni0poh9	51	4	contain	contain	VBP
cord-008530-yni0poh9	51	5	two	two	CD
cord-008530-yni0poh9	51	6	conserved	conserved	JJ
cord-008530-yni0poh9	51	7	cysteines	cysteine	NNS
cord-008530-yni0poh9	51	8	,	,	,
cord-008530-yni0poh9	51	9	one	one	CD
cord-008530-yni0poh9	51	10	in	in	IN
cord-008530-yni0poh9	51	11	the	the	DT
cord-008530-yni0poh9	51	12	NH2-terminal	nh2-terminal	JJ
cord-008530-yni0poh9	51	13	domain	domain	NN
cord-008530-yni0poh9	51	14	and	and	CC
cord-008530-yni0poh9	51	15	the	the	DT
cord-008530-yni0poh9	51	16	other	other	JJ
cord-008530-yni0poh9	51	17	in	in	IN
cord-008530-yni0poh9	51	18	the	the	DT
cord-008530-yni0poh9	51	19	third	third	JJ
cord-008530-yni0poh9	51	20	extracellular	extracellular	JJ
cord-008530-yni0poh9	51	21	loop	loop	NN
cord-008530-yni0poh9	51	22	;	;	:
cord-008530-yni0poh9	51	23	these	these	DT
cord-008530-yni0poh9	51	24	are	be	VBP
cord-008530-yni0poh9	51	25	assumed	assume	VBN
cord-008530-yni0poh9	51	26	to	to	TO
cord-008530-yni0poh9	51	27	form	form	VB
cord-008530-yni0poh9	51	28	disulfide	disulfide	JJ
cord-008530-yni0poh9	51	29	bonds	bond	NNS
cord-008530-yni0poh9	51	30	critical	critical	JJ
cord-008530-yni0poh9	51	31	for	for	IN
cord-008530-yni0poh9	51	32	the	the	DT
cord-008530-yni0poh9	51	33	formation	formation	NN
cord-008530-yni0poh9	51	34	of	of	IN
cord-008530-yni0poh9	51	35	the	the	DT
cord-008530-yni0poh9	51	36	ligand	ligand	NN
cord-008530-yni0poh9	51	37	binding	bind	VBG
cord-008530-yni0poh9	51	38	pocket	pocket	NN
cord-008530-yni0poh9	51	39	.	.	.
cord-008530-yni0poh9	52	1	In	in	IN
cord-008530-yni0poh9	52	2	accordance	accordance	NN
cord-008530-yni0poh9	52	3	with	with	IN
cord-008530-yni0poh9	52	4	the	the	DT
cord-008530-yni0poh9	52	5	chemokine	chemokine	NN
cord-008530-yni0poh9	52	6	classification	classification	NN
cord-008530-yni0poh9	52	7	,	,	,
cord-008530-yni0poh9	52	8	the	the	DT
cord-008530-yni0poh9	52	9	receptors	receptor	NNS
cord-008530-yni0poh9	52	10	are	be	VBP
cord-008530-yni0poh9	52	11	divided	divide	VBN
cord-008530-yni0poh9	52	12	into	into	IN
cord-008530-yni0poh9	52	13	four	four	CD
cord-008530-yni0poh9	52	14	major	major	JJ
cord-008530-yni0poh9	52	15	groups	group	NNS
cord-008530-yni0poh9	52	16	,	,	,
cord-008530-yni0poh9	52	17	CXCR	CXCR	NNP
cord-008530-yni0poh9	52	18	,	,	,
cord-008530-yni0poh9	52	19	CCR	CCR	NNP
cord-008530-yni0poh9	52	20	,	,	,
cord-008530-yni0poh9	52	21	XCR	XCR	NNP
cord-008530-yni0poh9	52	22	,	,	,
cord-008530-yni0poh9	52	23	and	and	CC
cord-008530-yni0poh9	52	24	CX3CR	CX3CR	NNP
cord-008530-yni0poh9	52	25	(	(	-LRB-
cord-008530-yni0poh9	52	26	Table	Table	NNP
cord-008530-yni0poh9	52	27	I	i	CD
cord-008530-yni0poh9	52	28	)	)	-RRB-
cord-008530-yni0poh9	52	29	.	.	.
cord-008530-yni0poh9	53	1	Individual	individual	JJ
cord-008530-yni0poh9	53	2	chemokine	chemokine	NN
cord-008530-yni0poh9	53	3	receptors	receptor	NNS
cord-008530-yni0poh9	53	4	may	may	MD
cord-008530-yni0poh9	53	5	often	often	RB
cord-008530-yni0poh9	53	6	be	be	VB
cord-008530-yni0poh9	53	7	promiscuous	promiscuous	JJ
cord-008530-yni0poh9	53	8	,	,	,
cord-008530-yni0poh9	53	9	meaning	mean	VBG
cord-008530-yni0poh9	53	10	that	that	IN
cord-008530-yni0poh9	53	11	they	-PRON-	PRP
cord-008530-yni0poh9	53	12	are	be	VBP
cord-008530-yni0poh9	53	13	capable	capable	JJ
cord-008530-yni0poh9	53	14	of	of	IN
cord-008530-yni0poh9	53	15	binding	bind	VBG
cord-008530-yni0poh9	53	16	several	several	JJ
cord-008530-yni0poh9	53	17	different	different	JJ
cord-008530-yni0poh9	53	18	chemokines	chemokine	NNS
cord-008530-yni0poh9	53	19	,	,	,
cord-008530-yni0poh9	53	20	and	and	CC
cord-008530-yni0poh9	53	21	conversely	conversely	RB
cord-008530-yni0poh9	53	22	,	,	,
cord-008530-yni0poh9	53	23	individual	individual	JJ
cord-008530-yni0poh9	53	24	chemokines	chemokine	NNS
cord-008530-yni0poh9	53	25	can	can	MD
cord-008530-yni0poh9	53	26	often	often	RB
cord-008530-yni0poh9	53	27	bind	bind	VB
cord-008530-yni0poh9	53	28	to	to	IN
cord-008530-yni0poh9	53	29	several	several	JJ
cord-008530-yni0poh9	53	30	different	different	JJ
cord-008530-yni0poh9	53	31	receptors	receptor	NNS
cord-008530-yni0poh9	53	32	.	.	.
cord-008530-yni0poh9	54	1	Interaction	interaction	NN
cord-008530-yni0poh9	54	2	between	between	IN
cord-008530-yni0poh9	54	3	a	a	DT
cord-008530-yni0poh9	54	4	chemokine	chemokine	NN
cord-008530-yni0poh9	54	5	and	and	CC
cord-008530-yni0poh9	54	6	its	-PRON-	PRP$
cord-008530-yni0poh9	54	7	receptor	receptor	NN
cord-008530-yni0poh9	54	8	leads	lead	VBZ
cord-008530-yni0poh9	54	9	to	to	IN
cord-008530-yni0poh9	54	10	generation	generation	NN
cord-008530-yni0poh9	54	11	of	of	IN
cord-008530-yni0poh9	54	12	a	a	DT
cord-008530-yni0poh9	54	13	coordinated	coordinated	JJ
cord-008530-yni0poh9	54	14	series	series	NN
cord-008530-yni0poh9	54	15	of	of	IN
cord-008530-yni0poh9	54	16	signaling	signal	VBG
cord-008530-yni0poh9	54	17	events	event	NNS
cord-008530-yni0poh9	54	18	such	such	JJ
cord-008530-yni0poh9	54	19	as	as	IN
cord-008530-yni0poh9	54	20	mobilization	mobilization	NN
cord-008530-yni0poh9	54	21	and	and	CC
cord-008530-yni0poh9	54	22	influx	influx	NN
cord-008530-yni0poh9	54	23	of	of	IN
cord-008530-yni0poh9	54	24	Ca	Ca	NNP
cord-008530-yni0poh9	54	25	2	2	CD
cord-008530-yni0poh9	54	26	+	+	SYM
cord-008530-yni0poh9	54	27	and	and	CC
cord-008530-yni0poh9	54	28	also	also	RB
cord-008530-yni0poh9	54	29	activation	activation	NN
cord-008530-yni0poh9	54	30	of	of	IN
cord-008530-yni0poh9	54	31	various	various	JJ
cord-008530-yni0poh9	54	32	signal	signal	NN
cord-008530-yni0poh9	54	33	transduction	transduction	NN
cord-008530-yni0poh9	54	34	pathways	pathway	NNS
cord-008530-yni0poh9	54	35	(	(	-LRB-
cord-008530-yni0poh9	54	36	Premack	Premack	NNP
cord-008530-yni0poh9	54	37	and	and	CC
cord-008530-yni0poh9	54	38	Schall	Schall	NNP
cord-008530-yni0poh9	54	39	,	,	,
cord-008530-yni0poh9	54	40	1996	1996	CD
cord-008530-yni0poh9	54	41	)	)	-RRB-
cord-008530-yni0poh9	54	42	.	.	.
cord-008530-yni0poh9	55	1	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	55	2	a	a	DT
cord-008530-yni0poh9	55	3	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	55	4	in	in	IN
cord-008530-yni0poh9	55	5	boldface	boldface	NN
cord-008530-yni0poh9	55	6	type	type	NN
cord-008530-yni0poh9	55	7	are	be	VBP
cord-008530-yni0poh9	55	8	cross	cross	NN
cord-008530-yni0poh9	55	9	-	-	JJ
cord-008530-yni0poh9	55	10	subfamily	subfamily	JJ
cord-008530-yni0poh9	55	11	ligand	ligand	NN
cord-008530-yni0poh9	55	12	-	-	HYPH
cord-008530-yni0poh9	55	13	binding	bind	VBG
cord-008530-yni0poh9	55	14	receptors	receptor	NNS
cord-008530-yni0poh9	55	15	.	.	.
cord-008530-yni0poh9	56	1	BCA-1	BCA-1	NNP
cord-008530-yni0poh9	56	2	/	/	SYM
cord-008530-yni0poh9	56	3	BLC	BLC	NNP
cord-008530-yni0poh9	56	4	,	,	,
cord-008530-yni0poh9	56	5	B	b	NN
cord-008530-yni0poh9	56	6	cell	cell	NN
cord-008530-yni0poh9	56	7	-	-	HYPH
cord-008530-yni0poh9	56	8	attracting	attract	VBG
cord-008530-yni0poh9	56	9	chemokine	chemokine	NN
cord-008530-yni0poh9	56	10	/	/	SYM
cord-008530-yni0poh9	56	11	B	b	NN
cord-008530-yni0poh9	56	12	-	-	HYPH
cord-008530-yni0poh9	56	13	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	56	14	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	56	15	;	;	:
cord-008530-yni0poh9	56	16	ELC	ELC	NNP
cord-008530-yni0poh9	56	17	,	,	,
cord-008530-yni0poh9	56	18	Epstein	Epstein	NNP
cord-008530-yni0poh9	56	19	-	-	HYPH
cord-008530-yni0poh9	56	20	Barr	Barr	NNP
cord-008530-yni0poh9	56	21	virus	virus	NN
cord-008530-yni0poh9	56	22	-	-	HYPH
cord-008530-yni0poh9	56	23	induced	induce	VBN
cord-008530-yni0poh9	56	24	receptor	receptor	NN
cord-008530-yni0poh9	56	25	ligand	ligand	NN
cord-008530-yni0poh9	56	26	chemokine	chemokine	NN
cord-008530-yni0poh9	56	27	;	;	.
cord-008530-yni0poh9	57	1	ENA-78	ENA-78	NNP
cord-008530-yni0poh9	57	2	,	,	,
cord-008530-yni0poh9	57	3	epithelial	epithelial	JJ
cord-008530-yni0poh9	57	4	cell	cell	NN
cord-008530-yni0poh9	57	5	-	-	HYPH
cord-008530-yni0poh9	57	6	derived	derive	VBN
cord-008530-yni0poh9	57	7	neutrophil	neutrophil	NN
cord-008530-yni0poh9	57	8	-	-	HYPH
cord-008530-yni0poh9	57	9	activating	activate	VBG
cord-008530-yni0poh9	57	10	factor-78	factor-78	CD
cord-008530-yni0poh9	57	11	;	;	.
cord-008530-yni0poh9	58	1	GCP-2	gcp-2	RB
cord-008530-yni0poh9	58	2	,	,	,
cord-008530-yni0poh9	58	3	granulocyte	granulocyte	NN
cord-008530-yni0poh9	58	4	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	58	5	protein-2	protein-2	VBZ
cord-008530-yni0poh9	58	6	;	;	:
cord-008530-yni0poh9	58	7	GRO	GRO	NNP
cord-008530-yni0poh9	58	8	,	,	,
cord-008530-yni0poh9	58	9	growth	growth	NN
cord-008530-yni0poh9	58	10	-	-	HYPH
cord-008530-yni0poh9	58	11	regulated	regulate	VBN
cord-008530-yni0poh9	58	12	oncogene	oncogene	NN
cord-008530-yni0poh9	58	13	;	;	.
cord-008530-yni0poh9	59	1	IL-8	IL-8	NNP
cord-008530-yni0poh9	59	2	,	,	,
cord-008530-yni0poh9	59	3	interleukin-8	interleukin-8	NNP
cord-008530-yni0poh9	59	4	;	;	:
cord-008530-yni0poh9	59	5	IP-10	IP-10	NNP
cord-008530-yni0poh9	59	6	,	,	,
cord-008530-yni0poh9	59	7	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	59	8	protein	protein	NN
cord-008530-yni0poh9	59	9	10	10	CD
cord-008530-yni0poh9	59	10	kD	kd	JJ
cord-008530-yni0poh9	59	11	;	;	:
cord-008530-yni0poh9	59	12	I	I	NNP
cord-008530-yni0poh9	59	13	-	-	HYPH
cord-008530-yni0poh9	59	14	TAC	TAC	NNP
cord-008530-yni0poh9	59	15	,	,	,
cord-008530-yni0poh9	59	16	interferoninducible	interferoninducible	JJ
cord-008530-yni0poh9	59	17	T	T	NNP
cord-008530-yni0poh9	59	18	cell	cell	NN
cord-008530-yni0poh9	59	19	alpha	alpha	NN
cord-008530-yni0poh9	59	20	-	-	HYPH
cord-008530-yni0poh9	59	21	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	59	22	;	;	:
cord-008530-yni0poh9	59	23	LARC	LARC	NNP
cord-008530-yni0poh9	59	24	,	,	,
cord-008530-yni0poh9	59	25	liver	liver	NN
cord-008530-yni0poh9	59	26	-	-	HYPH
cord-008530-yni0poh9	59	27	and	and	CC
cord-008530-yni0poh9	59	28	activation	activation	NN
cord-008530-yni0poh9	59	29	-	-	HYPH
cord-008530-yni0poh9	59	30	related	relate	VBN
cord-008530-yni0poh9	59	31	chemokine	chemokine	NN
cord-008530-yni0poh9	59	32	;	;	:
cord-008530-yni0poh9	59	33	LIX	LIX	NNP
cord-008530-yni0poh9	59	34	,	,	,
cord-008530-yni0poh9	59	35	LPS	LPS	NNP
cord-008530-yni0poh9	59	36	-	-	HYPH
cord-008530-yni0poh9	59	37	induced	induce	VBN
cord-008530-yni0poh9	59	38	CXC	CXC	NNP
cord-008530-yni0poh9	59	39	chemokine	chemokine	NN
cord-008530-yni0poh9	59	40	;	;	:
cord-008530-yni0poh9	59	41	MCP	MCP	NNP
cord-008530-yni0poh9	59	42	,	,	,
cord-008530-yni0poh9	59	43	monocyte	monocyte	NNP
cord-008530-yni0poh9	59	44	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	59	45	protein	protein	NN
cord-008530-yni0poh9	59	46	;	;	:
cord-008530-yni0poh9	59	47	Mig	Mig	NNP
cord-008530-yni0poh9	59	48	,	,	,
cord-008530-yni0poh9	59	49	monokine	monokine	NN
cord-008530-yni0poh9	59	50	induced	induce	VBN
cord-008530-yni0poh9	59	51	by	by	IN
cord-008530-yni0poh9	59	52	interferon	interferon	NN
cord-008530-yni0poh9	59	53	-	-	HYPH
cord-008530-yni0poh9	59	54	gamma	gamma	NN
cord-008530-yni0poh9	59	55	;	;	:
cord-008530-yni0poh9	59	56	MIP	MIP	NNP
cord-008530-yni0poh9	59	57	,	,	,
cord-008530-yni0poh9	59	58	macrophage	macrophage	NN
cord-008530-yni0poh9	59	59	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	59	60	protein	protein	NN
cord-008530-yni0poh9	59	61	;	;	.
cord-008530-yni0poh9	60	1	MRP-1	MRP-1	NNP
cord-008530-yni0poh9	60	2	,	,	,
cord-008530-yni0poh9	60	3	MIPrelated	miprelated	JJ
cord-008530-yni0poh9	60	4	protein	protein	NN
cord-008530-yni0poh9	60	5	1	1	CD
cord-008530-yni0poh9	60	6	;	;	:
cord-008530-yni0poh9	60	7	PBP	PBP	NNP
cord-008530-yni0poh9	60	8	,	,	,
cord-008530-yni0poh9	60	9	platelet	platelet	NN
cord-008530-yni0poh9	60	10	basic	basic	JJ
cord-008530-yni0poh9	60	11	protein	protein	NN
cord-008530-yni0poh9	60	12	;	;	:
cord-008530-yni0poh9	60	13	PF4	pf4	JJ
cord-008530-yni0poh9	60	14	,	,	,
cord-008530-yni0poh9	60	15	platelet	platelet	NN
cord-008530-yni0poh9	60	16	factor	factor	NN
cord-008530-yni0poh9	60	17	4	4	CD
cord-008530-yni0poh9	60	18	;	;	:
cord-008530-yni0poh9	60	19	RANTES	RANTES	NNP
cord-008530-yni0poh9	60	20	,	,	,
cord-008530-yni0poh9	60	21	regulated	regulate	VBN
cord-008530-yni0poh9	60	22	on	on	IN
cord-008530-yni0poh9	60	23	activation	activation	NN
cord-008530-yni0poh9	60	24	-	-	HYPH
cord-008530-yni0poh9	60	25	normal	normal	JJ
cord-008530-yni0poh9	60	26	T	T	NNP
cord-008530-yni0poh9	60	27	cell	cell	NN
cord-008530-yni0poh9	60	28	expressed	express	VBD
cord-008530-yni0poh9	60	29	and	and	CC
cord-008530-yni0poh9	60	30	secreted	secrete	VBN
cord-008530-yni0poh9	60	31	;	;	:
cord-008530-yni0poh9	60	32	SDF-1	sdf-1	NN
cord-008530-yni0poh9	60	33	,	,	,
cord-008530-yni0poh9	60	34	stromal	stromal	JJ
cord-008530-yni0poh9	60	35	cell	cell	NN
cord-008530-yni0poh9	60	36	-	-	HYPH
cord-008530-yni0poh9	60	37	derived	derive	VBN
cord-008530-yni0poh9	60	38	factor	factor	NN
cord-008530-yni0poh9	60	39	-	-	HYPH
cord-008530-yni0poh9	60	40	l	l	NN
cord-008530-yni0poh9	60	41	;	;	:
cord-008530-yni0poh9	60	42	SLC	SLC	NNP
cord-008530-yni0poh9	60	43	,	,	,
cord-008530-yni0poh9	60	44	secondary	secondary	JJ
cord-008530-yni0poh9	60	45	lymphoid	lymphoid	JJ
cord-008530-yni0poh9	60	46	tissue	tissue	NN
cord-008530-yni0poh9	60	47	chemokine	chemokine	NN
cord-008530-yni0poh9	60	48	;	;	:
cord-008530-yni0poh9	60	49	TECK	TECK	NNP
cord-008530-yni0poh9	60	50	,	,	,
cord-008530-yni0poh9	60	51	thymus	thymus	NN
cord-008530-yni0poh9	60	52	-	-	HYPH
cord-008530-yni0poh9	60	53	expressed	express	VBN
cord-008530-yni0poh9	60	54	chemokine	chemokine	NN
cord-008530-yni0poh9	60	55	.	.	.
cord-008530-yni0poh9	61	1	protein	protein	NNP
cord-008530-yni0poh9	61	2	10	10	CD
cord-008530-yni0poh9	61	3	kDa	kDa	NNPS
cord-008530-yni0poh9	61	4	)	)	-RRB-
cord-008530-yni0poh9	61	5	;	;	:
cord-008530-yni0poh9	61	6	and	and	CC
cord-008530-yni0poh9	61	7	Mig	Mig	NNP
cord-008530-yni0poh9	61	8	(	(	-LRB-
cord-008530-yni0poh9	61	9	monokine	monokine	NN
cord-008530-yni0poh9	61	10	induced	induce	VBN
cord-008530-yni0poh9	61	11	by	by	IN
cord-008530-yni0poh9	61	12	interferon	interferon	NN
cord-008530-yni0poh9	61	13	-	-	HYPH
cord-008530-yni0poh9	61	14	y	y	NNP
cord-008530-yni0poh9	61	15	)	)	-RRB-
cord-008530-yni0poh9	61	16	,	,	,
cord-008530-yni0poh9	61	17	(	(	-LRB-
cord-008530-yni0poh9	61	18	see	see	VB
cord-008530-yni0poh9	61	19	Fig	Fig	NNP
cord-008530-yni0poh9	61	20	.	.	.
cord-008530-yni0poh9	61	21	 	 	_SP
cord-008530-yni0poh9	61	22	1	1	CD
cord-008530-yni0poh9	61	23	)	)	-RRB-
cord-008530-yni0poh9	61	24	.	.	.
cord-008530-yni0poh9	62	1	The	the	DT
cord-008530-yni0poh9	62	2	presence	presence	NN
cord-008530-yni0poh9	62	3	or	or	CC
cord-008530-yni0poh9	62	4	absence	absence	NN
cord-008530-yni0poh9	62	5	of	of	IN
cord-008530-yni0poh9	62	6	an	an	DT
cord-008530-yni0poh9	62	7	ELR	ELR	NNP
cord-008530-yni0poh9	62	8	motif	motif	NN
cord-008530-yni0poh9	62	9	(	(	-LRB-
cord-008530-yni0poh9	62	10	glutamic	glutamic	JJ
cord-008530-yni0poh9	62	11	acid	acid	NN
cord-008530-yni0poh9	62	12	-	-	HYPH
cord-008530-yni0poh9	62	13	leucinearginine	leucinearginine	NN
cord-008530-yni0poh9	62	14	sequence	sequence	NN
cord-008530-yni0poh9	62	15	)	)	-RRB-
cord-008530-yni0poh9	62	16	preceding	precede	VBG
cord-008530-yni0poh9	62	17	the	the	DT
cord-008530-yni0poh9	62	18	first	first	JJ
cord-008530-yni0poh9	62	19	cysteine	cysteine	NN
cord-008530-yni0poh9	62	20	further	far	RBR
cord-008530-yni0poh9	62	21	subdivides	subdivide	VBZ
cord-008530-yni0poh9	62	22	the	the	DT
cord-008530-yni0poh9	62	23	CXC	CXC	NNP
cord-008530-yni0poh9	62	24	chemokines	chemokine	NNS
cord-008530-yni0poh9	62	25	into	into	IN
cord-008530-yni0poh9	62	26	ELR	ELR	NNP
cord-008530-yni0poh9	62	27	or	or	CC
cord-008530-yni0poh9	62	28	non	non	JJ
cord-008530-yni0poh9	62	29	-	-	JJ
cord-008530-yni0poh9	62	30	ELR	elr	JJ
cord-008530-yni0poh9	62	31	groups	group	NNS
cord-008530-yni0poh9	62	32	.	.	.
cord-008530-yni0poh9	63	1	Examples	example	NNS
cord-008530-yni0poh9	63	2	of	of	IN
cord-008530-yni0poh9	63	3	some	some	DT
cord-008530-yni0poh9	63	4	common	common	JJ
cord-008530-yni0poh9	63	5	ELR	ELR	NNP
cord-008530-yni0poh9	63	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	63	7	include	include	VBP
cord-008530-yni0poh9	63	8	IL-8	IL-8	NNP
cord-008530-yni0poh9	63	9	,	,	,
cord-008530-yni0poh9	63	10	GRO	GRO	NNP
cord-008530-yni0poh9	63	11	-	-	HYPH
cord-008530-yni0poh9	63	12	a	a	NN
cord-008530-yni0poh9	63	13	,	,	,
cord-008530-yni0poh9	63	14	and	and	CC
cord-008530-yni0poh9	63	15	MIP-2	MIP-2	NNP
cord-008530-yni0poh9	63	16	,	,	,
cord-008530-yni0poh9	63	17	while	while	IN
cord-008530-yni0poh9	63	18	non	non	JJ
cord-008530-yni0poh9	63	19	-	-	JJ
cord-008530-yni0poh9	63	20	ELR	elr	JJ
cord-008530-yni0poh9	63	21	chemokines	chemokine	NNS
cord-008530-yni0poh9	63	22	include	include	VBP
cord-008530-yni0poh9	63	23	IP-10	IP-10	NNP
cord-008530-yni0poh9	63	24	,	,	,
cord-008530-yni0poh9	63	25	Mig	Mig	NNP
cord-008530-yni0poh9	63	26	and	and	CC
cord-008530-yni0poh9	63	27	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	63	28	.	.	.
cord-008530-yni0poh9	64	1	This	this	DT
cord-008530-yni0poh9	64	2	grouping	group	VBG
cord-008530-yni0poh9	64	3	not	not	RB
cord-008530-yni0poh9	64	4	only	only	RB
cord-008530-yni0poh9	64	5	reflects	reflect	VBZ
cord-008530-yni0poh9	64	6	a	a	DT
cord-008530-yni0poh9	64	7	structural	structural	JJ
cord-008530-yni0poh9	64	8	compartmentalization	compartmentalization	NN
cord-008530-yni0poh9	64	9	,	,	,
cord-008530-yni0poh9	64	10	but	but	CC
cord-008530-yni0poh9	64	11	also	also	RB
cord-008530-yni0poh9	64	12	a	a	DT
cord-008530-yni0poh9	64	13	functional	functional	JJ
cord-008530-yni0poh9	64	14	one	one	NN
cord-008530-yni0poh9	64	15	in	in	IN
cord-008530-yni0poh9	64	16	that	that	DT
cord-008530-yni0poh9	64	17	ELR	ELR	NNP
cord-008530-yni0poh9	64	18	CXC	CXC	NNP
cord-008530-yni0poh9	64	19	chemokines	chemokine	NNS
cord-008530-yni0poh9	64	20	are	be	VBP
cord-008530-yni0poh9	64	21	predominantly	predominantly	RB
cord-008530-yni0poh9	64	22	chemoattractant	chemoattractant	JJ
cord-008530-yni0poh9	64	23	for	for	IN
cord-008530-yni0poh9	64	24	polymorphonuclear	polymorphonuclear	NNP
cord-008530-yni0poh9	64	25	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	64	26	and	and	CC
cord-008530-yni0poh9	64	27	bind	bind	VB
cord-008530-yni0poh9	64	28	to	to	IN
cord-008530-yni0poh9	64	29	the	the	DT
cord-008530-yni0poh9	64	30	CXCR1	CXCR1	NNS
cord-008530-yni0poh9	64	31	and	and	CC
cord-008530-yni0poh9	64	32	CXCR2	CXCR2	NNS
cord-008530-yni0poh9	64	33	receptors	receptor	NNS
cord-008530-yni0poh9	64	34	,	,	,
cord-008530-yni0poh9	64	35	while	while	IN
cord-008530-yni0poh9	64	36	non	non	JJ
cord-008530-yni0poh9	64	37	-	-	JJ
cord-008530-yni0poh9	64	38	ELR	elr	JJ
cord-008530-yni0poh9	64	39	chemokines	chemokine	NNS
cord-008530-yni0poh9	64	40	are	be	VBP
cord-008530-yni0poh9	64	41	chemoattractant	chemoattractant	JJ
cord-008530-yni0poh9	64	42	for	for	IN
cord-008530-yni0poh9	64	43	T	T	NNP
cord-008530-yni0poh9	64	44	and	and	CC
cord-008530-yni0poh9	64	45	B	b	NN
cord-008530-yni0poh9	64	46	cells	cell	NNS
cord-008530-yni0poh9	64	47	and	and	CC
cord-008530-yni0poh9	64	48	bind	bind	VB
cord-008530-yni0poh9	64	49	to	to	IN
cord-008530-yni0poh9	64	50	the	the	DT
cord-008530-yni0poh9	64	51	CXCR3	cxcr3	NN
cord-008530-yni0poh9	64	52	or	or	CC
cord-008530-yni0poh9	64	53	CXCR4	cxcr4	NN
cord-008530-yni0poh9	64	54	receptors	receptor	NNS
cord-008530-yni0poh9	64	55	.	.	.
cord-008530-yni0poh9	65	1	In	in	IN
cord-008530-yni0poh9	65	2	addition	addition	NN
cord-008530-yni0poh9	65	3	,	,	,
cord-008530-yni0poh9	65	4	members	member	NNS
cord-008530-yni0poh9	65	5	of	of	IN
cord-008530-yni0poh9	65	6	the	the	DT
cord-008530-yni0poh9	65	7	CXC	CXC	NNP
cord-008530-yni0poh9	65	8	chemokine	chemokine	NN
cord-008530-yni0poh9	65	9	family	family	NN
cord-008530-yni0poh9	65	10	can	can	MD
cord-008530-yni0poh9	65	11	either	either	CC
cord-008530-yni0poh9	65	12	promote	promote	VB
cord-008530-yni0poh9	65	13	or	or	CC
cord-008530-yni0poh9	65	14	inhibit	inhibit	VB
cord-008530-yni0poh9	65	15	anglogenesis	anglogenesis	NN
cord-008530-yni0poh9	65	16	,	,	,
cord-008530-yni0poh9	65	17	depending	depend	VBG
cord-008530-yni0poh9	65	18	on	on	IN
cord-008530-yni0poh9	65	19	whether	whether	IN
cord-008530-yni0poh9	65	20	they	-PRON-	PRP
cord-008530-yni0poh9	65	21	are	be	VBP
cord-008530-yni0poh9	65	22	ELR	ELR	NNP
cord-008530-yni0poh9	65	23	or	or	CC
cord-008530-yni0poh9	65	24	non	non	JJ
cord-008530-yni0poh9	65	25	-	-	JJ
cord-008530-yni0poh9	65	26	ELR	elr	JJ
cord-008530-yni0poh9	65	27	CXC	CXC	NNP
cord-008530-yni0poh9	65	28	chemokines	chemokine	NNS
cord-008530-yni0poh9	65	29	,	,	,
cord-008530-yni0poh9	65	30	respectively	respectively	RB
cord-008530-yni0poh9	65	31	.	.	.
cord-008530-yni0poh9	66	1	The	the	DT
cord-008530-yni0poh9	66	2	ELR	ELR	NNP
cord-008530-yni0poh9	66	3	-	-	HYPH
cord-008530-yni0poh9	66	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	66	5	are	be	VBP
cord-008530-yni0poh9	66	6	generally	generally	RB
cord-008530-yni0poh9	66	7	produced	produce	VBN
cord-008530-yni0poh9	66	8	during	during	IN
cord-008530-yni0poh9	66	9	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	66	10	responses	response	NNS
cord-008530-yni0poh9	66	11	provoked	provoke	VBN
cord-008530-yni0poh9	66	12	by	by	IN
cord-008530-yni0poh9	66	13	bacterial	bacterial	JJ
cord-008530-yni0poh9	66	14	infections	infection	NNS
cord-008530-yni0poh9	66	15	.	.	.
cord-008530-yni0poh9	67	1	On	on	IN
cord-008530-yni0poh9	67	2	the	the	DT
cord-008530-yni0poh9	67	3	other	other	JJ
cord-008530-yni0poh9	67	4	hand	hand	NN
cord-008530-yni0poh9	67	5	,	,	,
cord-008530-yni0poh9	67	6	production	production	NN
cord-008530-yni0poh9	67	7	of	of	IN
cord-008530-yni0poh9	67	8	the	the	DT
cord-008530-yni0poh9	67	9	non	non	JJ
cord-008530-yni0poh9	67	10	-	-	JJ
cord-008530-yni0poh9	67	11	ELR	elr	JJ
cord-008530-yni0poh9	67	12	chemokines	chemokine	NNS
cord-008530-yni0poh9	67	13	,	,	,
cord-008530-yni0poh9	67	14	IP-10	IP-10	NNP
cord-008530-yni0poh9	67	15	/	/	SYM
cord-008530-yni0poh9	67	16	crg-2	crg-2	NNP
cord-008530-yni0poh9	67	17	and	and	CC
cord-008530-yni0poh9	67	18	Mig	Mig	NNP
cord-008530-yni0poh9	67	19	,	,	,
cord-008530-yni0poh9	67	20	is	be	VBZ
cord-008530-yni0poh9	67	21	commonly	commonly	RB
cord-008530-yni0poh9	67	22	associated	associate	VBN
cord-008530-yni0poh9	67	23	with	with	IN
cord-008530-yni0poh9	67	24	viral	viral	JJ
cord-008530-yni0poh9	67	25	infections	infection	NNS
cord-008530-yni0poh9	67	26	where	where	WRB
cord-008530-yni0poh9	67	27	they	-PRON-	PRP
cord-008530-yni0poh9	67	28	likely	likely	RB
cord-008530-yni0poh9	67	29	function	function	VBP
cord-008530-yni0poh9	67	30	to	to	TO
cord-008530-yni0poh9	67	31	recruit	recruit	VB
cord-008530-yni0poh9	67	32	T	T	NNP
cord-008530-yni0poh9	67	33	cells	cell	NNS
cord-008530-yni0poh9	67	34	and	and	CC
cord-008530-yni0poh9	67	35	macrophages	macrophage	NNS
cord-008530-yni0poh9	67	36	that	that	WDT
cord-008530-yni0poh9	67	37	predominate	predominate	VBP
cord-008530-yni0poh9	67	38	at	at	IN
cord-008530-yni0poh9	67	39	sites	site	NNS
cord-008530-yni0poh9	67	40	of	of	IN
cord-008530-yni0poh9	67	41	infection	infection	NN
cord-008530-yni0poh9	68	1	(	(	-LRB-
cord-008530-yni0poh9	68	2	Amichay	Amichay	NNP
cord-008530-yni0poh9	68	3	et	et	FW
cord-008530-yni0poh9	68	4	al	al	NNP
cord-008530-yni0poh9	68	5	.	.	NNP
cord-008530-yni0poh9	68	6	,	,	,
cord-008530-yni0poh9	68	7	1996	1996	CD
cord-008530-yni0poh9	68	8	;	;	.
cord-008530-yni0poh9	69	1	Asensio	Asensio	NNP
cord-008530-yni0poh9	69	2	and	and	CC
cord-008530-yni0poh9	69	3	Campbell	Campbell	NNP
cord-008530-yni0poh9	69	4	,	,	,
cord-008530-yni0poh9	69	5	1997	1997	CD
cord-008530-yni0poh9	69	6	;	;	:
cord-008530-yni0poh9	69	7	Asensio	Asensio	NNP
cord-008530-yni0poh9	69	8	et	et	NNP
cord-008530-yni0poh9	69	9	al	al	NNP
cord-008530-yni0poh9	69	10	.	.	NNP
cord-008530-yni0poh9	69	11	,	,	,
cord-008530-yni0poh9	69	12	1999a	1999a	CD
cord-008530-yni0poh9	69	13	;	;	:
cord-008530-yni0poh9	70	1	Carr	Carr	NNP
cord-008530-yni0poh9	70	2	et	et	NNP
cord-008530-yni0poh9	70	3	al	al	NNP
cord-008530-yni0poh9	70	4	.	.	NNP
cord-008530-yni0poh9	70	5	,	,	,
cord-008530-yni0poh9	70	6	1998	1998	CD
cord-008530-yni0poh9	70	7	;	;	:
cord-008530-yni0poh9	70	8	Charles	Charles	NNP
cord-008530-yni0poh9	70	9	et	et	NNP
cord-008530-yni0poh9	70	10	al	al	NNP
cord-008530-yni0poh9	70	11	.	.	NNP
cord-008530-yni0poh9	70	12	,	,	,
cord-008530-yni0poh9	70	13	1999	1999	CD
cord-008530-yni0poh9	70	14	;	;	:
cord-008530-yni0poh9	71	1	Fisher	Fisher	NNP
cord-008530-yni0poh9	71	2	et	et	NNP
cord-008530-yni0poh9	71	3	al	al	NNP
cord-008530-yni0poh9	71	4	.	.	NNP
cord-008530-yni0poh9	71	5	,	,	,
cord-008530-yni0poh9	71	6	1995	1995	CD
cord-008530-yni0poh9	71	7	;	;	:
cord-008530-yni0poh9	71	8	Lahrtz	Lahrtz	NNP
cord-008530-yni0poh9	71	9	et	et	FW
cord-008530-yni0poh9	71	10	al	al	NNP
cord-008530-yni0poh9	71	11	.	.	NNP
cord-008530-yni0poh9	71	12	,	,	,
cord-008530-yni0poh9	71	13	1997	1997	CD
cord-008530-yni0poh9	72	1	;	;	:
cord-008530-yni0poh9	72	2	Nazar	Nazar	NNP
cord-008530-yni0poh9	72	3	et	et	NNP
cord-008530-yni0poh9	72	4	al	al	NNP
cord-008530-yni0poh9	72	5	.	.	NNP
cord-008530-yni0poh9	72	6	,	,	,
cord-008530-yni0poh9	72	7	1997	1997	CD
cord-008530-yni0poh9	72	8	;	;	:
cord-008530-yni0poh9	72	9	Vanguri	Vanguri	NNP
cord-008530-yni0poh9	72	10	and	and	CC
cord-008530-yni0poh9	72	11	Farber	Farber	NNP
cord-008530-yni0poh9	72	12	,	,	,
cord-008530-yni0poh9	72	13	1994	1994	CD
cord-008530-yni0poh9	72	14	)	)	-RRB-
cord-008530-yni0poh9	72	15	.	.	.
cord-008530-yni0poh9	73	1	This	this	DT
cord-008530-yni0poh9	73	2	scenario	scenario	NN
cord-008530-yni0poh9	73	3	is	be	VBZ
cord-008530-yni0poh9	73	4	borne	bear	VBN
cord-008530-yni0poh9	73	5	out	out	RP
cord-008530-yni0poh9	73	6	by	by	IN
cord-008530-yni0poh9	73	7	the	the	DT
cord-008530-yni0poh9	73	8	recent	recent	JJ
cord-008530-yni0poh9	73	9	demonstration	demonstration	NN
cord-008530-yni0poh9	73	10	of	of	IN
cord-008530-yni0poh9	73	11	pronounced	pronounced	JJ
cord-008530-yni0poh9	73	12	antiviral	antiviral	JJ
cord-008530-yni0poh9	73	13	activity	activity	NN
cord-008530-yni0poh9	73	14	of	of	IN
cord-008530-yni0poh9	73	15	Mig	Mig	NNP
cord-008530-yni0poh9	73	16	and	and	CC
cord-008530-yni0poh9	73	17	IP-10	IP-10	NNP
cord-008530-yni0poh9	73	18	when	when	WRB
cord-008530-yni0poh9	73	19	it	-PRON-	PRP
cord-008530-yni0poh9	73	20	is	be	VBZ
cord-008530-yni0poh9	73	21	expressed	express	VBN
cord-008530-yni0poh9	73	22	ectopically	ectopically	RB
cord-008530-yni0poh9	73	23	by	by	IN
cord-008530-yni0poh9	73	24	recombinant	recombinant	JJ
cord-008530-yni0poh9	73	25	vaccinia	vaccinia	NN
cord-008530-yni0poh9	73	26	viruses	virus	NNS
cord-008530-yni0poh9	73	27	(	(	-LRB-
cord-008530-yni0poh9	73	28	Mahalingam	Mahalingam	NNP
cord-008530-yni0poh9	73	29	et	et	NNP
cord-008530-yni0poh9	73	30	al	al	NNP
cord-008530-yni0poh9	73	31	.	.	NNP
cord-008530-yni0poh9	73	32	,	,	,
cord-008530-yni0poh9	73	33	1999	1999	CD
cord-008530-yni0poh9	73	34	)	)	-RRB-
cord-008530-yni0poh9	73	35	.	.	.
cord-008530-yni0poh9	74	1	The	the	DT
cord-008530-yni0poh9	74	2	antiviral	antiviral	JJ
cord-008530-yni0poh9	74	3	actions	action	NNS
cord-008530-yni0poh9	74	4	of	of	IN
cord-008530-yni0poh9	74	5	Mig	Mig	NNP
cord-008530-yni0poh9	74	6	and	and	CC
cord-008530-yni0poh9	74	7	IP-10	IP-10	NNP
cord-008530-yni0poh9	74	8	in	in	IN
cord-008530-yni0poh9	74	9	this	this	DT
cord-008530-yni0poh9	74	10	setting	setting	NN
cord-008530-yni0poh9	74	11	are	be	VBP
cord-008530-yni0poh9	74	12	mediated	mediate	VBN
cord-008530-yni0poh9	74	13	indirectly	indirectly	RB
cord-008530-yni0poh9	74	14	and	and	CC
cord-008530-yni0poh9	74	15	require	require	VB
cord-008530-yni0poh9	74	16	NK	NK	NNP
cord-008530-yni0poh9	74	17	cells	cell	NNS
cord-008530-yni0poh9	74	18	and	and	CC
cord-008530-yni0poh9	74	19	IFN	IFN	NNP
cord-008530-yni0poh9	74	20	-	-	HYPH
cord-008530-yni0poh9	74	21	a	a	NNP
cord-008530-yni0poh9	74	22	,	,	,
cord-008530-yni0poh9	74	23	IFN-~	IFN-~	NNP
cord-008530-yni0poh9	74	24	,	,	,
cord-008530-yni0poh9	74	25	and	and	CC
cord-008530-yni0poh9	74	26	IFN	IFN	NNP
cord-008530-yni0poh9	74	27	-	-	HYPH
cord-008530-yni0poh9	74	28	y	y	NNP
cord-008530-yni0poh9	74	29	.	.	.
cord-008530-yni0poh9	75	1	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	75	2	was	be	VBD
cord-008530-yni0poh9	75	3	originally	originally	RB
cord-008530-yni0poh9	75	4	isolated	isolate	VBN
cord-008530-yni0poh9	75	5	from	from	IN
cord-008530-yni0poh9	75	6	bone	bone	NN
cord-008530-yni0poh9	75	7	marrow	marrow	NN
cord-008530-yni0poh9	75	8	stromal	stromal	NN
cord-008530-yni0poh9	75	9	cells	cell	NNS
cord-008530-yni0poh9	75	10	as	as	IN
cord-008530-yni0poh9	75	11	a	a	DT
cord-008530-yni0poh9	75	12	pre	pre	NN
cord-008530-yni0poh9	75	13	-	-	JJ
cord-008530-yni0poh9	75	14	B	b	NN
cord-008530-yni0poh9	75	15	cell	cell	NN
cord-008530-yni0poh9	75	16	growth	growth	NN
cord-008530-yni0poh9	75	17	-	-	HYPH
cord-008530-yni0poh9	75	18	stimulating	stimulate	VBG
cord-008530-yni0poh9	75	19	factor	factor	NN
cord-008530-yni0poh9	75	20	.	.	.
cord-008530-yni0poh9	76	1	In	in	IN
cord-008530-yni0poh9	76	2	contrast	contrast	NN
cord-008530-yni0poh9	76	3	to	to	IN
cord-008530-yni0poh9	76	4	IP-10	IP-10	NNP
cord-008530-yni0poh9	76	5	and	and	CC
cord-008530-yni0poh9	76	6	Mig	Mig	NNP
cord-008530-yni0poh9	76	7	,	,	,
cord-008530-yni0poh9	76	8	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	76	9	is	be	VBZ
cord-008530-yni0poh9	76	10	produced	produce	VBN
cord-008530-yni0poh9	76	11	constitutively	constitutively	RB
cord-008530-yni0poh9	76	12	in	in	IN
cord-008530-yni0poh9	76	13	many	many	JJ
cord-008530-yni0poh9	76	14	organs	organ	NNS
cord-008530-yni0poh9	76	15	(	(	-LRB-
cord-008530-yni0poh9	76	16	e.g.	e.g.	RB
cord-008530-yni0poh9	76	17	,	,	,
cord-008530-yni0poh9	76	18	heart	heart	NN
cord-008530-yni0poh9	76	19	,	,	,
cord-008530-yni0poh9	76	20	lung	lung	NN
cord-008530-yni0poh9	76	21	,	,	,
cord-008530-yni0poh9	76	22	and	and	CC
cord-008530-yni0poh9	76	23	CNS	CNS	NNP
cord-008530-yni0poh9	76	24	)	)	-RRB-
cord-008530-yni0poh9	76	25	and	and	CC
cord-008530-yni0poh9	76	26	binds	bind	VBZ
cord-008530-yni0poh9	76	27	to	to	IN
cord-008530-yni0poh9	76	28	the	the	DT
cord-008530-yni0poh9	76	29	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	76	30	receptor	receptor	NN
cord-008530-yni0poh9	76	31	.	.	.
cord-008530-yni0poh9	77	1	Animals	animal	NNS
cord-008530-yni0poh9	77	2	lacking	lack	VBG
cord-008530-yni0poh9	77	3	SDF-1	sdf-1	NN
cord-008530-yni0poh9	77	4	or	or	CC
cord-008530-yni0poh9	77	5	its	-PRON-	PRP$
cord-008530-yni0poh9	77	6	receptor	receptor	NN
cord-008530-yni0poh9	77	7	invariably	invariably	RB
cord-008530-yni0poh9	77	8	die	die	VBP
cord-008530-yni0poh9	77	9	at	at	IN
cord-008530-yni0poh9	77	10	or	or	CC
cord-008530-yni0poh9	77	11	soon	soon	RB
cord-008530-yni0poh9	77	12	after	after	IN
cord-008530-yni0poh9	77	13	birth	birth	NN
cord-008530-yni0poh9	77	14	and	and	CC
cord-008530-yni0poh9	77	15	have	have	VBP
cord-008530-yni0poh9	77	16	major	major	JJ
cord-008530-yni0poh9	77	17	abnormalities	abnormality	NNS
cord-008530-yni0poh9	77	18	affecting	affect	VBG
cord-008530-yni0poh9	77	19	the	the	DT
cord-008530-yni0poh9	77	20	immune	immune	JJ
cord-008530-yni0poh9	77	21	system	system	NN
cord-008530-yni0poh9	77	22	(	(	-LRB-
cord-008530-yni0poh9	77	23	an	an	DT
cord-008530-yni0poh9	77	24	impairment	impairment	NN
cord-008530-yni0poh9	77	25	in	in	IN
cord-008530-yni0poh9	77	26	B	b	NN
cord-008530-yni0poh9	77	27	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	77	28	development	development	NN
cord-008530-yni0poh9	77	29	)	)	-RRB-
cord-008530-yni0poh9	77	30	as	as	RB
cord-008530-yni0poh9	77	31	well	well	RB
cord-008530-yni0poh9	77	32	as	as	IN
cord-008530-yni0poh9	77	33	various	various	JJ
cord-008530-yni0poh9	77	34	organs	organ	NNS
cord-008530-yni0poh9	77	35	including	include	VBG
cord-008530-yni0poh9	77	36	the	the	DT
cord-008530-yni0poh9	77	37	heart	heart	NN
cord-008530-yni0poh9	77	38	and	and	CC
cord-008530-yni0poh9	77	39	CNS	CNS	NNP
cord-008530-yni0poh9	77	40	Nagasawa	Nagasawa	NNP
cord-008530-yni0poh9	77	41	et	et	NNP
cord-008530-yni0poh9	77	42	al	al	NNP
cord-008530-yni0poh9	77	43	.	.	.
cord-008530-yni0poh9	78	1	,	,	,
cord-008530-yni0poh9	78	2	1996	1996	CD
cord-008530-yni0poh9	78	3	;	;	:
cord-008530-yni0poh9	78	4	Tachibana	Tachibana	NNP
cord-008530-yni0poh9	78	5	et	et	NNP
cord-008530-yni0poh9	78	6	al	al	NNP
cord-008530-yni0poh9	78	7	.	.	NNP
cord-008530-yni0poh9	78	8	,	,	,
cord-008530-yni0poh9	78	9	1998	1998	CD
cord-008530-yni0poh9	78	10	;	;	:
cord-008530-yni0poh9	78	11	Zou	Zou	NNP
cord-008530-yni0poh9	78	12	et	et	FW
cord-008530-yni0poh9	78	13	al	al	NNP
cord-008530-yni0poh9	78	14	.	.	NNP
cord-008530-yni0poh9	78	15	,	,	,
cord-008530-yni0poh9	78	16	1998	1998	CD
cord-008530-yni0poh9	78	17	)	)	-RRB-
cord-008530-yni0poh9	78	18	.	.	.
cord-008530-yni0poh9	79	1	These	these	DT
cord-008530-yni0poh9	79	2	studies	study	NNS
cord-008530-yni0poh9	79	3	revealed	reveal	VBD
cord-008530-yni0poh9	79	4	that	that	IN
cord-008530-yni0poh9	79	5	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	79	6	is	be	VBZ
cord-008530-yni0poh9	79	7	a	a	DT
cord-008530-yni0poh9	79	8	crucial	crucial	JJ
cord-008530-yni0poh9	79	9	mediator	mediator	NN
cord-008530-yni0poh9	79	10	of	of	IN
cord-008530-yni0poh9	79	11	cellular	cellular	JJ
cord-008530-yni0poh9	79	12	migration	migration	NN
cord-008530-yni0poh9	79	13	and	and	CC
cord-008530-yni0poh9	79	14	patterning	patterning	NN
cord-008530-yni0poh9	79	15	during	during	IN
cord-008530-yni0poh9	79	16	organogenesis	organogenesi	NNS
cord-008530-yni0poh9	79	17	.	.	.
cord-008530-yni0poh9	80	1	To	to	IN
cord-008530-yni0poh9	80	2	date	date	NN
cord-008530-yni0poh9	80	3	,	,	,
cord-008530-yni0poh9	80	4	5	5	CD
cord-008530-yni0poh9	80	5	CXC	CXC	NNP
cord-008530-yni0poh9	80	6	chemokine	chemokine	NN
cord-008530-yni0poh9	80	7	receptors	receptor	NNS
cord-008530-yni0poh9	80	8	have	have	VBP
cord-008530-yni0poh9	80	9	been	be	VBN
cord-008530-yni0poh9	80	10	described	describe	VBN
cord-008530-yni0poh9	80	11	and	and	CC
cord-008530-yni0poh9	80	12	their	-PRON-	PRP$
cord-008530-yni0poh9	80	13	ligands	ligand	NNS
cord-008530-yni0poh9	80	14	identified	identify	VBN
cord-008530-yni0poh9	80	15	(	(	-LRB-
cord-008530-yni0poh9	80	16	see	see	VB
cord-008530-yni0poh9	80	17	Table	table	NN
cord-008530-yni0poh9	80	18	I	-PRON-	PRP
cord-008530-yni0poh9	80	19	)	)	-RRB-
cord-008530-yni0poh9	81	1	(	(	-LRB-
cord-008530-yni0poh9	81	2	Baggiolini	Baggiolini	NNP
cord-008530-yni0poh9	81	3	et	et	NNP
cord-008530-yni0poh9	81	4	al	al	NNP
cord-008530-yni0poh9	81	5	.	.	NNP
cord-008530-yni0poh9	81	6	,	,	,
cord-008530-yni0poh9	81	7	1997	1997	CD
cord-008530-yni0poh9	81	8	;	;	:
cord-008530-yni0poh9	81	9	Mackay	Mackay	NNP
cord-008530-yni0poh9	81	10	,	,	,
cord-008530-yni0poh9	81	11	1997	1997	CD
cord-008530-yni0poh9	81	12	;	;	:
cord-008530-yni0poh9	81	13	Moser	Moser	NNP
cord-008530-yni0poh9	81	14	et	et	NNP
cord-008530-yni0poh9	81	15	al	al	NNP
cord-008530-yni0poh9	81	16	.	.	NNP
cord-008530-yni0poh9	81	17	,	,	,
cord-008530-yni0poh9	81	18	1998	1998	CD
cord-008530-yni0poh9	81	19	)	)	-RRB-
cord-008530-yni0poh9	81	20	.	.	.
cord-008530-yni0poh9	82	1	Most	Most	JJS
cord-008530-yni0poh9	82	2	of	of	IN
cord-008530-yni0poh9	82	3	the	the	DT
cord-008530-yni0poh9	82	4	early	early	JJ
cord-008530-yni0poh9	82	5	characterization	characterization	NN
cord-008530-yni0poh9	82	6	of	of	IN
cord-008530-yni0poh9	82	7	the	the	DT
cord-008530-yni0poh9	82	8	CXC	CXC	NNP
cord-008530-yni0poh9	82	9	chemokine	chemokine	NN
cord-008530-yni0poh9	82	10	receptors	receptor	NNS
cord-008530-yni0poh9	82	11	was	be	VBD
cord-008530-yni0poh9	82	12	done	do	VBN
cord-008530-yni0poh9	82	13	with	with	IN
cord-008530-yni0poh9	82	14	the	the	DT
cord-008530-yni0poh9	82	15	IL-8	IL-8	NNP
cord-008530-yni0poh9	82	16	receptors	receptor	NNS
cord-008530-yni0poh9	82	17	CXCR1	CXCR1	NNP
cord-008530-yni0poh9	82	18	(	(	-LRB-
cord-008530-yni0poh9	82	19	also	also	RB
cord-008530-yni0poh9	82	20	known	know	VBN
cord-008530-yni0poh9	82	21	as	as	IN
cord-008530-yni0poh9	82	22	IL-8RA	il-8ra	RB
cord-008530-yni0poh9	82	23	)	)	-RRB-
cord-008530-yni0poh9	83	1	and	and	CC
cord-008530-yni0poh9	83	2	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	83	3	(	(	-LRB-
cord-008530-yni0poh9	83	4	also	also	RB
cord-008530-yni0poh9	83	5	known	know	VBN
cord-008530-yni0poh9	83	6	as	as	IN
cord-008530-yni0poh9	83	7	IL-8RB	IL-8RB	NNP
cord-008530-yni0poh9	83	8	)	)	-RRB-
cord-008530-yni0poh9	83	9	.	.	.
cord-008530-yni0poh9	84	1	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	84	2	is	be	VBZ
cord-008530-yni0poh9	84	3	expressed	express	VBN
cord-008530-yni0poh9	84	4	on	on	IN
cord-008530-yni0poh9	84	5	a	a	DT
cord-008530-yni0poh9	84	6	variety	variety	NN
cord-008530-yni0poh9	84	7	of	of	IN
cord-008530-yni0poh9	84	8	cells	cell	NNS
cord-008530-yni0poh9	84	9	including	include	VBG
cord-008530-yni0poh9	84	10	T	t	NN
cord-008530-yni0poh9	84	11	cells	cell	NNS
cord-008530-yni0poh9	84	12	,	,	,
cord-008530-yni0poh9	84	13	monocytes	monocyte	NNS
cord-008530-yni0poh9	84	14	,	,	,
cord-008530-yni0poh9	84	15	melanoma	melanoma	NN
cord-008530-yni0poh9	84	16	cells	cell	NNS
cord-008530-yni0poh9	84	17	,	,	,
cord-008530-yni0poh9	84	18	synovial	synovial	JJ
cord-008530-yni0poh9	84	19	cells	cell	NNS
cord-008530-yni0poh9	84	20	,	,	,
cord-008530-yni0poh9	84	21	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	84	22	,	,	,
cord-008530-yni0poh9	84	23	and	and	CC
cord-008530-yni0poh9	84	24	myeloid	myeloid	JJ
cord-008530-yni0poh9	84	25	precursor	precursor	NN
cord-008530-yni0poh9	84	26	cells	cell	NNS
cord-008530-yni0poh9	84	27	.	.	.
cord-008530-yni0poh9	85	1	Expression	expression	NN
cord-008530-yni0poh9	85	2	of	of	IN
cord-008530-yni0poh9	85	3	CXCR1	cxcr1	NN
cord-008530-yni0poh9	85	4	is	be	VBZ
cord-008530-yni0poh9	85	5	restricted	restrict	VBN
cord-008530-yni0poh9	85	6	largely	largely	RB
cord-008530-yni0poh9	85	7	to	to	IN
cord-008530-yni0poh9	85	8	myeloid	myeloid	NN
cord-008530-yni0poh9	85	9	cells	cell	NNS
cord-008530-yni0poh9	85	10	and	and	CC
cord-008530-yni0poh9	85	11	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	85	12	.	.	.
cord-008530-yni0poh9	86	1	While	while	IN
cord-008530-yni0poh9	86	2	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	86	3	binds	bind	VBZ
cord-008530-yni0poh9	86	4	all	all	PDT
cord-008530-yni0poh9	86	5	the	the	DT
cord-008530-yni0poh9	86	6	ELR	ELR	NNP
cord-008530-yni0poh9	86	7	-	-	HYPH
cord-008530-yni0poh9	86	8	chemokines	chemokine	NNS
cord-008530-yni0poh9	86	9	,	,	,
cord-008530-yni0poh9	86	10	CXCR1	cxcr1	NN
cord-008530-yni0poh9	86	11	binds	bind	VBZ
cord-008530-yni0poh9	86	12	only	only	RB
cord-008530-yni0poh9	86	13	IL-8	il-8	NN
cord-008530-yni0poh9	86	14	.	.	.
cord-008530-yni0poh9	87	1	Mice	mouse	NNS
cord-008530-yni0poh9	87	2	lacking	lack	VBG
cord-008530-yni0poh9	87	3	CXCR2	CXCR2	NNS
cord-008530-yni0poh9	87	4	show	show	VBP
cord-008530-yni0poh9	87	5	normal	normal	JJ
cord-008530-yni0poh9	87	6	development	development	NN
cord-008530-yni0poh9	87	7	of	of	IN
cord-008530-yni0poh9	87	8	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	87	9	but	but	CC
cord-008530-yni0poh9	87	10	have	have	VBP
cord-008530-yni0poh9	87	11	decreased	decrease	VBN
cord-008530-yni0poh9	87	12	numbers	number	NNS
cord-008530-yni0poh9	87	13	of	of	IN
cord-008530-yni0poh9	87	14	myeloid	myeloid	JJ
cord-008530-yni0poh9	87	15	progenitors	progenitor	NNS
cord-008530-yni0poh9	87	16	(	(	-LRB-
cord-008530-yni0poh9	87	17	Broxmeyer	Broxmeyer	NNP
cord-008530-yni0poh9	87	18	et	et	NNP
cord-008530-yni0poh9	87	19	al	al	NNP
cord-008530-yni0poh9	87	20	.	.	.
cord-008530-yni0poh9	88	1	,	,	,
cord-008530-yni0poh9	88	2	1996	1996	CD
cord-008530-yni0poh9	88	3	;	;	:
cord-008530-yni0poh9	88	4	Cacalano	Cacalano	NNP
cord-008530-yni0poh9	88	5	et	et	NNP
cord-008530-yni0poh9	88	6	al	al	NNP
cord-008530-yni0poh9	88	7	.	.	NNP
cord-008530-yni0poh9	88	8	,	,	,
cord-008530-yni0poh9	88	9	1994	1994	CD
cord-008530-yni0poh9	88	10	)	)	-RRB-
cord-008530-yni0poh9	88	11	.	.	.
cord-008530-yni0poh9	89	1	CXCR2-deficient	CXCR2-deficient	JJR
cord-008530-yni0poh9	89	2	mice	mouse	NNS
cord-008530-yni0poh9	89	3	do	do	VBP
cord-008530-yni0poh9	89	4	not	not	RB
cord-008530-yni0poh9	89	5	exhibit	exhibit	VB
cord-008530-yni0poh9	89	6	any	any	DT
cord-008530-yni0poh9	89	7	other	other	JJ
cord-008530-yni0poh9	89	8	overt	overt	JJ
cord-008530-yni0poh9	89	9	pathologic	pathologic	JJ
cord-008530-yni0poh9	89	10	abnormalities	abnormality	NNS
cord-008530-yni0poh9	89	11	.	.	.
cord-008530-yni0poh9	90	1	CXCR3	CXCR3	NNP
cord-008530-yni0poh9	90	2	is	be	VBZ
cord-008530-yni0poh9	90	3	the	the	DT
cord-008530-yni0poh9	90	4	receptor	receptor	NN
cord-008530-yni0poh9	90	5	for	for	IN
cord-008530-yni0poh9	90	6	several	several	JJ
cord-008530-yni0poh9	90	7	of	of	IN
cord-008530-yni0poh9	90	8	the	the	DT
cord-008530-yni0poh9	90	9	non	non	JJ
cord-008530-yni0poh9	90	10	-	-	JJ
cord-008530-yni0poh9	90	11	ELR	ELR	NNP
cord-008530-yni0poh9	90	12	CXC	CXC	NNP
cord-008530-yni0poh9	90	13	chemokines	chemokine	NNS
cord-008530-yni0poh9	90	14	,	,	,
cord-008530-yni0poh9	90	15	IP-10	IP-10	NNP
cord-008530-yni0poh9	90	16	,	,	,
cord-008530-yni0poh9	90	17	Mig	Mig	NNP
cord-008530-yni0poh9	90	18	and	and	CC
cord-008530-yni0poh9	90	19	I	I	NNP
cord-008530-yni0poh9	90	20	-	-	HYPH
cord-008530-yni0poh9	90	21	TAC	TAC	NNP
cord-008530-yni0poh9	90	22	.	.	.
cord-008530-yni0poh9	91	1	Surprisingly	surprisingly	RB
cord-008530-yni0poh9	91	2	,	,	,
cord-008530-yni0poh9	91	3	some	some	DT
cord-008530-yni0poh9	91	4	CC	cc	NN
cord-008530-yni0poh9	91	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	91	6	such	such	JJ
cord-008530-yni0poh9	91	7	as	as	IN
cord-008530-yni0poh9	91	8	eotaxin	eotaxin	NNP
cord-008530-yni0poh9	91	9	,	,	,
cord-008530-yni0poh9	91	10	MCP-4	MCP-4	NNP
cord-008530-yni0poh9	92	1	(	(	-LRB-
cord-008530-yni0poh9	92	2	Weng	Weng	NNP
cord-008530-yni0poh9	92	3	et	et	NNP
cord-008530-yni0poh9	92	4	al	al	NNP
cord-008530-yni0poh9	92	5	.	.	NNP
cord-008530-yni0poh9	92	6	,	,	,
cord-008530-yni0poh9	92	7	1998	1998	CD
cord-008530-yni0poh9	92	8	)	)	-RRB-
cord-008530-yni0poh9	92	9	,	,	,
cord-008530-yni0poh9	92	10	and	and	CC
cord-008530-yni0poh9	93	1	6Ckine	6Ckine	NNP
cord-008530-yni0poh9	93	2	(	(	-LRB-
cord-008530-yni0poh9	93	3	also	also	RB
cord-008530-yni0poh9	93	4	called	call	VBN
cord-008530-yni0poh9	93	5	exodus	exodus	NN
cord-008530-yni0poh9	93	6	2	2	CD
cord-008530-yni0poh9	93	7	or	or	CC
cord-008530-yni0poh9	93	8	SLC	SLC	NNP
cord-008530-yni0poh9	93	9	)	)	-RRB-
cord-008530-yni0poh9	93	10	also	also	RB
cord-008530-yni0poh9	93	11	bind	bind	VBP
cord-008530-yni0poh9	93	12	to	to	IN
cord-008530-yni0poh9	93	13	CXCR3	cxcr3	XX
cord-008530-yni0poh9	93	14	.	.	.
cord-008530-yni0poh9	94	1	Through	through	IN
cord-008530-yni0poh9	94	2	this	this	DT
cord-008530-yni0poh9	94	3	interaction	interaction	NN
cord-008530-yni0poh9	94	4	,	,	,
cord-008530-yni0poh9	94	5	eotaxin	eotaxin	NNP
cord-008530-yni0poh9	94	6	does	do	VBZ
cord-008530-yni0poh9	94	7	not	not	RB
cord-008530-yni0poh9	94	8	activate	activate	VB
cord-008530-yni0poh9	94	9	the	the	DT
cord-008530-yni0poh9	94	10	CXCR3	cxcr3	NN
cord-008530-yni0poh9	94	11	receptor	receptor	NN
cord-008530-yni0poh9	94	12	but	but	CC
cord-008530-yni0poh9	94	13	effectively	effectively	RB
cord-008530-yni0poh9	94	14	blocks	block	VBZ
cord-008530-yni0poh9	94	15	IP-10	IP-10	NNP
cord-008530-yni0poh9	94	16	binding	bind	VBG
cord-008530-yni0poh9	94	17	and	and	CC
cord-008530-yni0poh9	94	18	prevents	prevent	VBZ
cord-008530-yni0poh9	94	19	receptor	receptor	NN
cord-008530-yni0poh9	94	20	activation	activation	NN
cord-008530-yni0poh9	94	21	.	.	.
cord-008530-yni0poh9	95	1	Thus	thus	RB
cord-008530-yni0poh9	95	2	,	,	,
cord-008530-yni0poh9	95	3	these	these	DT
cord-008530-yni0poh9	95	4	CC	CC	NNP
cord-008530-yni0poh9	95	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	95	6	may	may	MD
cord-008530-yni0poh9	95	7	serve	serve	VB
cord-008530-yni0poh9	95	8	as	as	IN
cord-008530-yni0poh9	95	9	natural	natural	JJ
cord-008530-yni0poh9	95	10	CXCR3	CXCR3	NNP
cord-008530-yni0poh9	95	11	antagonists	antagonist	NNS
cord-008530-yni0poh9	95	12	highlighting	highlight	VBG
cord-008530-yni0poh9	95	13	complexity	complexity	NN
cord-008530-yni0poh9	95	14	in	in	IN
cord-008530-yni0poh9	95	15	the	the	DT
cord-008530-yni0poh9	95	16	regulation	regulation	NN
cord-008530-yni0poh9	95	17	of	of	IN
cord-008530-yni0poh9	95	18	chemokine	chemokine	NN
cord-008530-yni0poh9	95	19	actions	action	NNS
cord-008530-yni0poh9	95	20	.	.	.
cord-008530-yni0poh9	96	1	Human	Human	NNP
cord-008530-yni0poh9	96	2	CXCR3	CXCR3	NNP
cord-008530-yni0poh9	96	3	has	have	VBZ
cord-008530-yni0poh9	96	4	been	be	VBN
cord-008530-yni0poh9	96	5	shown	show	VBN
cord-008530-yni0poh9	96	6	to	to	TO
cord-008530-yni0poh9	96	7	be	be	VB
cord-008530-yni0poh9	96	8	produced	produce	VBN
cord-008530-yni0poh9	96	9	specifically	specifically	RB
cord-008530-yni0poh9	96	10	by	by	IN
cord-008530-yni0poh9	96	11	IL-2-activated	il-2-activated	CD
cord-008530-yni0poh9	96	12	CD4	CD4	NNP
cord-008530-yni0poh9	96	13	÷	÷	NNP
cord-008530-yni0poh9	96	14	T	T	NNP
cord-008530-yni0poh9	96	15	cells	cell	NNS
cord-008530-yni0poh9	96	16	,	,	,
cord-008530-yni0poh9	96	17	B	b	NN
cord-008530-yni0poh9	96	18	cells	cell	NNS
cord-008530-yni0poh9	96	19	,	,	,
cord-008530-yni0poh9	96	20	and	and	CC
cord-008530-yni0poh9	96	21	NK	NK	NNP
cord-008530-yni0poh9	96	22	cells	cell	NNS
cord-008530-yni0poh9	96	23	.	.	.
cord-008530-yni0poh9	97	1	CD8	CD8	NNP
cord-008530-yni0poh9	97	2	÷	÷	NNP
cord-008530-yni0poh9	97	3	T	T	NNP
cord-008530-yni0poh9	97	4	cell	cell	NN
cord-008530-yni0poh9	97	5	and	and	CC
cord-008530-yni0poh9	97	6	NK	NK	NNP
cord-008530-yni0poh9	97	7	cell	cell	NN
cord-008530-yni0poh9	97	8	clones	clone	NNS
cord-008530-yni0poh9	97	9	have	have	VBP
cord-008530-yni0poh9	97	10	also	also	RB
cord-008530-yni0poh9	97	11	been	be	VBN
cord-008530-yni0poh9	97	12	shown	show	VBN
cord-008530-yni0poh9	97	13	to	to	TO
cord-008530-yni0poh9	97	14	express	express	VB
cord-008530-yni0poh9	97	15	the	the	DT
cord-008530-yni0poh9	97	16	CXCR3	CXCR3	NNP
cord-008530-yni0poh9	97	17	receptor	receptor	NN
cord-008530-yni0poh9	97	18	.	.	.
cord-008530-yni0poh9	98	1	This	this	DT
cord-008530-yni0poh9	98	2	suggests	suggest	VBZ
cord-008530-yni0poh9	98	3	non	non	JJ
cord-008530-yni0poh9	98	4	-	-	JJ
cord-008530-yni0poh9	98	5	ELR	elr	JJ
cord-008530-yni0poh9	98	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	98	7	such	such	JJ
cord-008530-yni0poh9	98	8	as	as	IN
cord-008530-yni0poh9	98	9	IP-10	IP-10	NNP
cord-008530-yni0poh9	98	10	may	may	MD
cord-008530-yni0poh9	98	11	exert	exert	VB
cord-008530-yni0poh9	98	12	a	a	DT
cord-008530-yni0poh9	98	13	selective	selective	JJ
cord-008530-yni0poh9	98	14	influence	influence	NN
cord-008530-yni0poh9	98	15	on	on	IN
cord-008530-yni0poh9	98	16	Thl	Thl	NNP
cord-008530-yni0poh9	98	17	and	and	CC
cord-008530-yni0poh9	98	18	cytotoxic	cytotoxic	JJ
cord-008530-yni0poh9	98	19	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	98	20	and	and	CC
cord-008530-yni0poh9	98	21	NK	NK	NNP
cord-008530-yni0poh9	98	22	cell	cell	NN
cord-008530-yni0poh9	98	23	recruitment	recruitment	NN
cord-008530-yni0poh9	98	24	,	,	,
cord-008530-yni0poh9	98	25	which	which	WDT
cord-008530-yni0poh9	98	26	may	may	MD
cord-008530-yni0poh9	98	27	be	be	VB
cord-008530-yni0poh9	98	28	important	important	JJ
cord-008530-yni0poh9	98	29	in	in	IN
cord-008530-yni0poh9	98	30	the	the	DT
cord-008530-yni0poh9	98	31	development	development	NN
cord-008530-yni0poh9	98	32	of	of	IN
cord-008530-yni0poh9	98	33	innate	innate	JJ
cord-008530-yni0poh9	98	34	and	and	CC
cord-008530-yni0poh9	98	35	adaptive	adaptive	JJ
cord-008530-yni0poh9	98	36	immune	immune	JJ
cord-008530-yni0poh9	98	37	responses	response	NNS
cord-008530-yni0poh9	98	38	to	to	IN
cord-008530-yni0poh9	98	39	viral	viral	JJ
cord-008530-yni0poh9	98	40	infections	infection	NNS
cord-008530-yni0poh9	98	41	.	.	.
cord-008530-yni0poh9	99	1	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	99	2	and	and	CC
cord-008530-yni0poh9	99	3	CXCR5	CXCR5	NNP
cord-008530-yni0poh9	99	4	bind	bind	VB
cord-008530-yni0poh9	99	5	the	the	DT
cord-008530-yni0poh9	99	6	other	other	JJ
cord-008530-yni0poh9	99	7	non	non	JJ
cord-008530-yni0poh9	99	8	-	-	JJ
cord-008530-yni0poh9	99	9	ELR	elr	JJ
cord-008530-yni0poh9	99	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	99	11	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	99	12	and	and	CC
cord-008530-yni0poh9	99	13	BCA	BCA	NNP
cord-008530-yni0poh9	99	14	,	,	,
cord-008530-yni0poh9	99	15	respectively	respectively	RB
cord-008530-yni0poh9	99	16	.	.	.
cord-008530-yni0poh9	100	1	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	100	2	,	,	,
cord-008530-yni0poh9	100	3	also	also	RB
cord-008530-yni0poh9	100	4	known	know	VBN
cord-008530-yni0poh9	100	5	as	as	IN
cord-008530-yni0poh9	100	6	LESTR	LESTR	NNP
cord-008530-yni0poh9	100	7	or	or	CC
cord-008530-yni0poh9	100	8	fusin	fusin	NNP
cord-008530-yni0poh9	100	9	,	,	,
cord-008530-yni0poh9	100	10	serves	serve	VBZ
cord-008530-yni0poh9	100	11	as	as	IN
cord-008530-yni0poh9	100	12	a	a	DT
cord-008530-yni0poh9	100	13	major	major	JJ
cord-008530-yni0poh9	100	14	coreceptor	coreceptor	NN
cord-008530-yni0poh9	100	15	for	for	IN
cord-008530-yni0poh9	100	16	lymphotropic	lymphotropic	JJ
cord-008530-yni0poh9	100	17	strains	strain	NNS
cord-008530-yni0poh9	100	18	of	of	IN
cord-008530-yni0poh9	100	19	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	101	1	(	(	-LRB-
cord-008530-yni0poh9	101	2	Deng	Deng	NNP
cord-008530-yni0poh9	101	3	et	et	NNP
cord-008530-yni0poh9	101	4	al	al	NNP
cord-008530-yni0poh9	101	5	.	.	NNP
cord-008530-yni0poh9	101	6	,	,	,
cord-008530-yni0poh9	101	7	1996	1996	CD
cord-008530-yni0poh9	102	1	;	;	:
cord-008530-yni0poh9	102	2	Feng	Feng	NNP
cord-008530-yni0poh9	102	3	et	et	FW
cord-008530-yni0poh9	102	4	al	al	NNP
cord-008530-yni0poh9	102	5	.	.	NNP
cord-008530-yni0poh9	102	6	,	,	,
cord-008530-yni0poh9	102	7	1996	1996	CD
cord-008530-yni0poh9	102	8	)	)	-RRB-
cord-008530-yni0poh9	102	9	and	and	CC
cord-008530-yni0poh9	102	10	is	be	VBZ
cord-008530-yni0poh9	102	11	expressed	express	VBN
cord-008530-yni0poh9	102	12	in	in	IN
cord-008530-yni0poh9	102	13	a	a	DT
cord-008530-yni0poh9	102	14	variety	variety	NN
cord-008530-yni0poh9	102	15	of	of	IN
cord-008530-yni0poh9	102	16	tissues	tissue	NNS
cord-008530-yni0poh9	102	17	including	include	VBG
cord-008530-yni0poh9	102	18	brain	brain	NN
cord-008530-yni0poh9	102	19	,	,	,
cord-008530-yni0poh9	102	20	heart	heart	NN
cord-008530-yni0poh9	102	21	,	,	,
cord-008530-yni0poh9	102	22	liver	liver	NN
cord-008530-yni0poh9	102	23	,	,	,
cord-008530-yni0poh9	102	24	and	and	CC
cord-008530-yni0poh9	102	25	colon	colon	NN
cord-008530-yni0poh9	102	26	and	and	CC
cord-008530-yni0poh9	102	27	in	in	IN
cord-008530-yni0poh9	102	28	nonhematopoietic	nonhematopoietic	JJ
cord-008530-yni0poh9	102	29	cells	cell	NNS
cord-008530-yni0poh9	103	1	(	(	-LRB-
cord-008530-yni0poh9	103	2	Lavi	Lavi	NNP
cord-008530-yni0poh9	103	3	et	et	NNP
cord-008530-yni0poh9	103	4	al	al	NNP
cord-008530-yni0poh9	103	5	.	.	NNP
cord-008530-yni0poh9	103	6	,	,	,
cord-008530-yni0poh9	103	7	1997	1997	CD
cord-008530-yni0poh9	103	8	;	;	.
cord-008530-yni0poh9	104	1	Ohtani	Ohtani	NNP
cord-008530-yni0poh9	104	2	et	et	NNP
cord-008530-yni0poh9	104	3	al	al	NNP
cord-008530-yni0poh9	104	4	.	.	NNP
cord-008530-yni0poh9	104	5	,	,	,
cord-008530-yni0poh9	104	6	1998	1998	CD
cord-008530-yni0poh9	104	7	)	)	-RRB-
cord-008530-yni0poh9	104	8	.	.	.
cord-008530-yni0poh9	105	1	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	106	1	mRNA	mRNA	NNP
cord-008530-yni0poh9	106	2	expression	expression	NN
cord-008530-yni0poh9	106	3	is	be	VBZ
cord-008530-yni0poh9	106	4	also	also	RB
cord-008530-yni0poh9	106	5	found	find	VBN
cord-008530-yni0poh9	106	6	in	in	IN
cord-008530-yni0poh9	106	7	murine	murine	JJ
cord-008530-yni0poh9	106	8	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	106	9	,	,	,
cord-008530-yni0poh9	106	10	macrophages	macrophage	NNS
cord-008530-yni0poh9	106	11	,	,	,
cord-008530-yni0poh9	106	12	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	106	13	,	,	,
cord-008530-yni0poh9	106	14	and	and	CC
cord-008530-yni0poh9	106	15	glial	glial	JJ
cord-008530-yni0poh9	106	16	cells	cell	NNS
cord-008530-yni0poh9	106	17	.	.	.
cord-008530-yni0poh9	107	1	As	as	IN
cord-008530-yni0poh9	107	2	indicated	indicate	VBN
cord-008530-yni0poh9	107	3	above	above	RB
cord-008530-yni0poh9	107	4	,	,	,
cord-008530-yni0poh9	107	5	disruption	disruption	NN
cord-008530-yni0poh9	107	6	of	of	IN
cord-008530-yni0poh9	107	7	the	the	DT
cord-008530-yni0poh9	107	8	CXCR4	cxcr4	NN
cord-008530-yni0poh9	107	9	gene	gene	NN
cord-008530-yni0poh9	107	10	causes	cause	VBZ
cord-008530-yni0poh9	107	11	defects	defect	NNS
cord-008530-yni0poh9	107	12	in	in	IN
cord-008530-yni0poh9	107	13	vascular	vascular	JJ
cord-008530-yni0poh9	107	14	development	development	NN
cord-008530-yni0poh9	107	15	,	,	,
cord-008530-yni0poh9	107	16	hematopoiesis	hematopoiesis	NNP
cord-008530-yni0poh9	107	17	,	,	,
cord-008530-yni0poh9	107	18	cardiogenesis	cardiogenesis	NNP
cord-008530-yni0poh9	107	19	,	,	,
cord-008530-yni0poh9	107	20	and	and	CC
cord-008530-yni0poh9	107	21	neurogenesis	neurogenesis	NN
cord-008530-yni0poh9	107	22	of	of	IN
cord-008530-yni0poh9	107	23	the	the	DT
cord-008530-yni0poh9	107	24	cerebellum	cerebellum	NN
cord-008530-yni0poh9	107	25	.	.	.
cord-008530-yni0poh9	108	1	CXCR5	CXCR5	NNP
cord-008530-yni0poh9	108	2	,	,	,
cord-008530-yni0poh9	108	3	originally	originally	RB
cord-008530-yni0poh9	108	4	described	describe	VBN
cord-008530-yni0poh9	108	5	as	as	IN
cord-008530-yni0poh9	108	6	BLR-1	BLR-1	NNP
cord-008530-yni0poh9	109	1	(	(	-LRB-
cord-008530-yni0poh9	109	2	Burkitt	Burkitt	NNP
cord-008530-yni0poh9	109	3	's	's	POS
cord-008530-yni0poh9	109	4	lymphoma	lymphoma	NN
cord-008530-yni0poh9	109	5	receptor	receptor	NN
cord-008530-yni0poh9	109	6	-	-	HYPH
cord-008530-yni0poh9	109	7	l	l	NN
cord-008530-yni0poh9	109	8	)	)	-RRB-
cord-008530-yni0poh9	109	9	,	,	,
cord-008530-yni0poh9	109	10	is	be	VBZ
cord-008530-yni0poh9	109	11	highly	highly	RB
cord-008530-yni0poh9	109	12	related	related	JJ
cord-008530-yni0poh9	109	13	to	to	IN
cord-008530-yni0poh9	109	14	the	the	DT
cord-008530-yni0poh9	109	15	IL-8	il-8	NN
cord-008530-yni0poh9	109	16	receptors	receptor	NNS
cord-008530-yni0poh9	109	17	(	(	-LRB-
cord-008530-yni0poh9	109	18	Dobner	Dobner	NNP
cord-008530-yni0poh9	109	19	et	et	NNP
cord-008530-yni0poh9	109	20	al	al	NNP
cord-008530-yni0poh9	109	21	.	.	NNP
cord-008530-yni0poh9	109	22	,	,	,
cord-008530-yni0poh9	109	23	1992	1992	CD
cord-008530-yni0poh9	109	24	)	)	-RRB-
cord-008530-yni0poh9	109	25	.	.	.
cord-008530-yni0poh9	110	1	CXCR5	CXCR5	NNP
cord-008530-yni0poh9	111	1	mRNA	mRNA	NNP
cord-008530-yni0poh9	111	2	is	be	VBZ
cord-008530-yni0poh9	111	3	expressed	express	VBN
cord-008530-yni0poh9	111	4	by	by	IN
cord-008530-yni0poh9	111	5	B	b	NN
cord-008530-yni0poh9	111	6	cell	cell	NN
cord-008530-yni0poh9	111	7	lymphomas	lymphoma	NNS
cord-008530-yni0poh9	111	8	and	and	CC
cord-008530-yni0poh9	111	9	by	by	IN
cord-008530-yni0poh9	111	10	granule	granule	NN
cord-008530-yni0poh9	111	11	and	and	CC
cord-008530-yni0poh9	111	12	Purkinje	Purkinje	NNP
cord-008530-yni0poh9	111	13	cells	cell	NNS
cord-008530-yni0poh9	111	14	of	of	IN
cord-008530-yni0poh9	111	15	the	the	DT
cord-008530-yni0poh9	111	16	cerebellum	cerebellum	NN
cord-008530-yni0poh9	111	17	.	.	.
cord-008530-yni0poh9	112	1	Therefore	therefore	RB
cord-008530-yni0poh9	112	2	,	,	,
cord-008530-yni0poh9	112	3	in	in	IN
cord-008530-yni0poh9	112	4	addition	addition	NN
cord-008530-yni0poh9	112	5	to	to	IN
cord-008530-yni0poh9	112	6	regulation	regulation	NN
cord-008530-yni0poh9	112	7	of	of	IN
cord-008530-yni0poh9	112	8	recirculating	recirculate	VBG
cord-008530-yni0poh9	112	9	mature	mature	JJ
cord-008530-yni0poh9	112	10	B	b	NN
cord-008530-yni0poh9	112	11	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	112	12	(	(	-LRB-
cord-008530-yni0poh9	112	13	Forster	Forster	NNP
cord-008530-yni0poh9	112	14	et	et	NNP
cord-008530-yni0poh9	112	15	al	al	NNP
cord-008530-yni0poh9	112	16	.	.	NNP
cord-008530-yni0poh9	112	17	,	,	,
cord-008530-yni0poh9	112	18	1996	1996	CD
cord-008530-yni0poh9	112	19	;	;	:
cord-008530-yni0poh9	112	20	Forster	Forster	NNP
cord-008530-yni0poh9	112	21	et	et	NNP
cord-008530-yni0poh9	112	22	al	al	NNP
cord-008530-yni0poh9	112	23	.	.	NNP
cord-008530-yni0poh9	112	24	,	,	,
cord-008530-yni0poh9	112	25	1994	1994	CD
cord-008530-yni0poh9	112	26	;	;	:
cord-008530-yni0poh9	112	27	Kaiser	Kaiser	NNP
cord-008530-yni0poh9	112	28	et	et	NNP
cord-008530-yni0poh9	112	29	al	al	NNP
cord-008530-yni0poh9	112	30	.	.	NNP
cord-008530-yni0poh9	112	31	,	,	,
cord-008530-yni0poh9	112	32	1993	1993	CD
cord-008530-yni0poh9	112	33	)	)	-RRB-
cord-008530-yni0poh9	112	34	,	,	,
cord-008530-yni0poh9	112	35	this	this	DT
cord-008530-yni0poh9	112	36	receptor	receptor	NN
cord-008530-yni0poh9	112	37	may	may	MD
cord-008530-yni0poh9	112	38	be	be	VB
cord-008530-yni0poh9	112	39	involved	involve	VBN
cord-008530-yni0poh9	112	40	in	in	IN
cord-008530-yni0poh9	112	41	some	some	DT
cord-008530-yni0poh9	112	42	CNS	CNS	NNP
cord-008530-yni0poh9	112	43	functions	function	NNS
cord-008530-yni0poh9	112	44	.	.	.
cord-008530-yni0poh9	113	1	However	however	RB
cord-008530-yni0poh9	113	2	,	,	,
cord-008530-yni0poh9	113	3	mice	mouse	NNS
cord-008530-yni0poh9	113	4	lacking	lack	VBG
cord-008530-yni0poh9	113	5	CXCR5	CXCR5	NNP
cord-008530-yni0poh9	113	6	show	show	VBP
cord-008530-yni0poh9	113	7	significant	significant	JJ
cord-008530-yni0poh9	113	8	phenotypic	phenotypic	JJ
cord-008530-yni0poh9	113	9	changes	change	NNS
cord-008530-yni0poh9	113	10	in	in	IN
cord-008530-yni0poh9	113	11	lymphoid	lymphoid	JJ
cord-008530-yni0poh9	113	12	organs	organ	NNS
cord-008530-yni0poh9	113	13	but	but	CC
cord-008530-yni0poh9	113	14	not	not	RB
cord-008530-yni0poh9	113	15	in	in	IN
cord-008530-yni0poh9	113	16	the	the	DT
cord-008530-yni0poh9	113	17	brain	brain	NN
cord-008530-yni0poh9	113	18	,	,	,
cord-008530-yni0poh9	113	19	suggesting	suggest	VBG
cord-008530-yni0poh9	113	20	that	that	IN
cord-008530-yni0poh9	113	21	this	this	DT
cord-008530-yni0poh9	113	22	receptor	receptor	NN
cord-008530-yni0poh9	113	23	,	,	,
cord-008530-yni0poh9	113	24	unlike	unlike	IN
cord-008530-yni0poh9	113	25	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	113	26	,	,	,
cord-008530-yni0poh9	113	27	does	do	VBZ
cord-008530-yni0poh9	113	28	not	not	RB
cord-008530-yni0poh9	113	29	play	play	VB
cord-008530-yni0poh9	113	30	an	an	DT
cord-008530-yni0poh9	113	31	obligatory	obligatory	JJ
cord-008530-yni0poh9	113	32	role	role	NN
cord-008530-yni0poh9	113	33	in	in	IN
cord-008530-yni0poh9	113	34	CNS	CNS	NNP
cord-008530-yni0poh9	113	35	development	development	NN
cord-008530-yni0poh9	114	1	(	(	-LRB-
cord-008530-yni0poh9	114	2	Forster	Forster	NNP
cord-008530-yni0poh9	114	3	et	et	NNP
cord-008530-yni0poh9	114	4	al	al	NNP
cord-008530-yni0poh9	114	5	.	.	NNP
cord-008530-yni0poh9	114	6	,	,	,
cord-008530-yni0poh9	114	7	1996	1996	CD
cord-008530-yni0poh9	114	8	)	)	-RRB-
cord-008530-yni0poh9	114	9	.	.	.
cord-008530-yni0poh9	115	1	The	the	DT
cord-008530-yni0poh9	115	2	CC	CC	NNP
cord-008530-yni0poh9	115	3	or	or	CC
cord-008530-yni0poh9	115	4	~-chemokines	~-chemokine	NNS
cord-008530-yni0poh9	115	5	contain	contain	VBP
cord-008530-yni0poh9	115	6	the	the	DT
cord-008530-yni0poh9	115	7	largest	large	JJS
cord-008530-yni0poh9	115	8	number	number	NN
cord-008530-yni0poh9	115	9	of	of	IN
cord-008530-yni0poh9	115	10	members	member	NNS
cord-008530-yni0poh9	115	11	and	and	CC
cord-008530-yni0poh9	115	12	are	be	VBP
cord-008530-yni0poh9	115	13	so	so	RB
cord-008530-yni0poh9	115	14	named	name	VBN
cord-008530-yni0poh9	115	15	because	because	IN
cord-008530-yni0poh9	115	16	the	the	DT
cord-008530-yni0poh9	115	17	NH2-terminal	NH2-terminal	NNP
cord-008530-yni0poh9	115	18	cysteines	cysteine	NNS
cord-008530-yni0poh9	115	19	are	be	VBP
cord-008530-yni0poh9	115	20	adjacent	adjacent	JJ
cord-008530-yni0poh9	115	21	to	to	IN
cord-008530-yni0poh9	115	22	each	each	DT
cord-008530-yni0poh9	115	23	other	other	JJ
cord-008530-yni0poh9	115	24	.	.	.
cord-008530-yni0poh9	116	1	Individual	Individual	NNP
cord-008530-yni0poh9	116	2	CC	CC	NNP
cord-008530-yni0poh9	116	3	chemokines	chemokine	NNS
cord-008530-yni0poh9	116	4	may	may	MD
cord-008530-yni0poh9	116	5	exert	exert	VB
cord-008530-yni0poh9	116	6	their	-PRON-	PRP$
cord-008530-yni0poh9	116	7	actions	action	NNS
cord-008530-yni0poh9	116	8	on	on	IN
cord-008530-yni0poh9	116	9	multiple	multiple	JJ
cord-008530-yni0poh9	116	10	leukocyte	leukocyte	NN
cord-008530-yni0poh9	116	11	subtypes	subtype	NNS
cord-008530-yni0poh9	116	12	,	,	,
cord-008530-yni0poh9	116	13	including	include	VBG
cord-008530-yni0poh9	116	14	monocytes	monocyte	NNS
cord-008530-yni0poh9	116	15	,	,	,
cord-008530-yni0poh9	116	16	basophils	basophil	NNS
cord-008530-yni0poh9	116	17	,	,	,
cord-008530-yni0poh9	116	18	eosinophils	eosinophil	NNS
cord-008530-yni0poh9	116	19	,	,	,
cord-008530-yni0poh9	116	20	T	t	NN
cord-008530-yni0poh9	116	21	cells	cell	NNS
cord-008530-yni0poh9	116	22	,	,	,
cord-008530-yni0poh9	116	23	dendritic	dendritic	JJ
cord-008530-yni0poh9	116	24	cells	cell	NNS
cord-008530-yni0poh9	116	25	,	,	,
cord-008530-yni0poh9	116	26	and	and	CC
cord-008530-yni0poh9	116	27	natural	natural	JJ
cord-008530-yni0poh9	116	28	killer	killer	NN
cord-008530-yni0poh9	116	29	cells	cell	NNS
cord-008530-yni0poh9	116	30	.	.	.
cord-008530-yni0poh9	117	1	Well	well	RB
cord-008530-yni0poh9	117	2	-	-	HYPH
cord-008530-yni0poh9	117	3	known	know	VBN
cord-008530-yni0poh9	117	4	members	member	NNS
cord-008530-yni0poh9	117	5	of	of	IN
cord-008530-yni0poh9	117	6	this	this	DT
cord-008530-yni0poh9	117	7	family	family	NN
cord-008530-yni0poh9	117	8	include	include	VBP
cord-008530-yni0poh9	117	9	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	117	10	,	,	,
cord-008530-yni0poh9	117	11	MIP	MIP	NNP
cord-008530-yni0poh9	117	12	-	-	HYPH
cord-008530-yni0poh9	117	13	la	la	NNP
cord-008530-yni0poh9	117	14	,	,	,
cord-008530-yni0poh9	117	15	C10	C10	NNP
cord-008530-yni0poh9	117	16	,	,	,
cord-008530-yni0poh9	117	17	eotaxin	eotaxin	NNP
cord-008530-yni0poh9	117	18	,	,	,
cord-008530-yni0poh9	117	19	and	and	CC
cord-008530-yni0poh9	117	20	RANTES	RANTES	NNP
cord-008530-yni0poh9	117	21	.	.	.
cord-008530-yni0poh9	118	1	A	a	DT
cord-008530-yni0poh9	118	2	more	more	RBR
cord-008530-yni0poh9	118	3	comprehensive	comprehensive	JJ
cord-008530-yni0poh9	118	4	list	list	NN
cord-008530-yni0poh9	118	5	of	of	IN
cord-008530-yni0poh9	118	6	the	the	DT
cord-008530-yni0poh9	118	7	members	member	NNS
cord-008530-yni0poh9	118	8	of	of	IN
cord-008530-yni0poh9	118	9	this	this	DT
cord-008530-yni0poh9	118	10	family	family	NN
cord-008530-yni0poh9	118	11	can	can	MD
cord-008530-yni0poh9	118	12	be	be	VB
cord-008530-yni0poh9	118	13	found	find	VBN
cord-008530-yni0poh9	118	14	in	in	IN
cord-008530-yni0poh9	118	15	Fig	Fig	NNP
cord-008530-yni0poh9	118	16	.	.	.
cord-008530-yni0poh9	119	1	1	1	LS
cord-008530-yni0poh9	119	2	.	.	.
cord-008530-yni0poh9	120	1	One	one	CD
cord-008530-yni0poh9	120	2	of	of	IN
cord-008530-yni0poh9	120	3	the	the	DT
cord-008530-yni0poh9	120	4	most	most	RBS
cord-008530-yni0poh9	120	5	studied	studied	JJ
cord-008530-yni0poh9	120	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	120	7	of	of	IN
cord-008530-yni0poh9	120	8	this	this	DT
cord-008530-yni0poh9	120	9	family	family	NN
cord-008530-yni0poh9	120	10	is	be	VBZ
cord-008530-yni0poh9	120	11	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	120	12	,	,	,
cord-008530-yni0poh9	120	13	which	which	WDT
cord-008530-yni0poh9	120	14	attracts	attract	VBZ
cord-008530-yni0poh9	120	15	T	t	NN
cord-008530-yni0poh9	120	16	cells	cell	NNS
cord-008530-yni0poh9	120	17	and	and	CC
cord-008530-yni0poh9	120	18	monocytes	monocyte	NNS
cord-008530-yni0poh9	120	19	but	but	CC
cord-008530-yni0poh9	120	20	not	not	RB
cord-008530-yni0poh9	120	21	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	120	22	(	(	-LRB-
cord-008530-yni0poh9	120	23	Carr	Carr	NNP
cord-008530-yni0poh9	120	24	et	et	FW
cord-008530-yni0poh9	120	25	al	al	NNP
cord-008530-yni0poh9	120	26	.	.	.
cord-008530-yni0poh9	121	1	,	,	,
cord-008530-yni0poh9	121	2	1994	1994	CD
cord-008530-yni0poh9	121	3	;	;	:
cord-008530-yni0poh9	121	4	Matsushima	Matsushima	NNP
cord-008530-yni0poh9	121	5	et	et	NNP
cord-008530-yni0poh9	121	6	al	al	NNP
cord-008530-yni0poh9	121	7	.	.	NNP
cord-008530-yni0poh9	121	8	,	,	,
cord-008530-yni0poh9	121	9	1989	1989	CD
cord-008530-yni0poh9	121	10	)	)	-RRB-
cord-008530-yni0poh9	121	11	.	.	.
cord-008530-yni0poh9	122	1	Mice	mouse	NNS
cord-008530-yni0poh9	122	2	with	with	IN
cord-008530-yni0poh9	122	3	targeted	target	VBN
cord-008530-yni0poh9	122	4	disruption	disruption	NN
cord-008530-yni0poh9	122	5	of	of	IN
cord-008530-yni0poh9	122	6	the	the	DT
cord-008530-yni0poh9	122	7	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	122	8	gene	gene	NN
cord-008530-yni0poh9	122	9	have	have	VBP
cord-008530-yni0poh9	122	10	defects	defect	NNS
cord-008530-yni0poh9	122	11	in	in	IN
cord-008530-yni0poh9	122	12	monocyte	monocyte	NNP
cord-008530-yni0poh9	122	13	/	/	SYM
cord-008530-yni0poh9	122	14	macrophage	macrophage	NN
cord-008530-yni0poh9	122	15	recruitment	recruitment	NN
cord-008530-yni0poh9	122	16	in	in	IN
cord-008530-yni0poh9	122	17	a	a	DT
cord-008530-yni0poh9	122	18	variety	variety	NN
cord-008530-yni0poh9	122	19	of	of	IN
cord-008530-yni0poh9	122	20	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	122	21	and	and	CC
cord-008530-yni0poh9	122	22	immunological	immunological	JJ
cord-008530-yni0poh9	122	23	models	model	NNS
cord-008530-yni0poh9	122	24	.	.	.
cord-008530-yni0poh9	123	1	Conversely	conversely	RB
cord-008530-yni0poh9	123	2	,	,	,
cord-008530-yni0poh9	123	3	transgenic	transgenic	JJ
cord-008530-yni0poh9	123	4	mice	mouse	NNS
cord-008530-yni0poh9	123	5	with	with	IN
cord-008530-yni0poh9	123	6	expression	expression	NN
cord-008530-yni0poh9	123	7	of	of	IN
cord-008530-yni0poh9	123	8	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	123	9	targeted	target	VBN
cord-008530-yni0poh9	123	10	to	to	IN
cord-008530-yni0poh9	123	11	pancreatic	pancreatic	JJ
cord-008530-yni0poh9	123	12	islets	islet	NNS
cord-008530-yni0poh9	124	1	(	(	-LRB-
cord-008530-yni0poh9	124	2	Grewal	Grewal	NNP
cord-008530-yni0poh9	124	3	et	et	NNP
cord-008530-yni0poh9	124	4	al	al	NNP
cord-008530-yni0poh9	124	5	.	.	NNP
cord-008530-yni0poh9	124	6	,	,	,
cord-008530-yni0poh9	124	7	1997	1997	CD
cord-008530-yni0poh9	124	8	)	)	-RRB-
cord-008530-yni0poh9	124	9	or	or	CC
cord-008530-yni0poh9	124	10	oligodendrocytes	oligodendrocyte	NNS
cord-008530-yni0poh9	124	11	in	in	IN
cord-008530-yni0poh9	124	12	the	the	DT
cord-008530-yni0poh9	124	13	brain	brain	NN
cord-008530-yni0poh9	125	1	(	(	-LRB-
cord-008530-yni0poh9	125	2	Fuentes	Fuentes	NNP
cord-008530-yni0poh9	125	3	et	et	NNP
cord-008530-yni0poh9	125	4	al	al	NNP
cord-008530-yni0poh9	125	5	.	.	NNP
cord-008530-yni0poh9	125	6	,	,	,
cord-008530-yni0poh9	125	7	1995	1995	CD
cord-008530-yni0poh9	125	8	)	)	-RRB-
cord-008530-yni0poh9	125	9	show	show	VBP
cord-008530-yni0poh9	125	10	an	an	DT
cord-008530-yni0poh9	125	11	accumulation	accumulation	NN
cord-008530-yni0poh9	125	12	of	of	IN
cord-008530-yni0poh9	125	13	monocytes	monocyte	NNS
cord-008530-yni0poh9	125	14	at	at	IN
cord-008530-yni0poh9	125	15	these	these	DT
cord-008530-yni0poh9	125	16	sites	site	NNS
cord-008530-yni0poh9	125	17	.	.	.
cord-008530-yni0poh9	126	1	Interestingly	interestingly	RB
cord-008530-yni0poh9	126	2	,	,	,
cord-008530-yni0poh9	126	3	these	these	DT
cord-008530-yni0poh9	126	4	accumulating	accumulate	VBG
cord-008530-yni0poh9	126	5	monocytes	monocyte	NNS
cord-008530-yni0poh9	126	6	showed	show	VBD
cord-008530-yni0poh9	126	7	little	little	JJ
cord-008530-yni0poh9	126	8	evidence	evidence	NN
cord-008530-yni0poh9	126	9	of	of	IN
cord-008530-yni0poh9	126	10	activation	activation	NN
cord-008530-yni0poh9	126	11	,	,	,
cord-008530-yni0poh9	126	12	indicating	indicate	VBG
cord-008530-yni0poh9	126	13	that	that	IN
cord-008530-yni0poh9	126	14	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	126	15	is	be	VBZ
cord-008530-yni0poh9	126	16	an	an	DT
cord-008530-yni0poh9	126	17	effective	effective	JJ
cord-008530-yni0poh9	126	18	monocyte	monocyte	NNP
cord-008530-yni0poh9	126	19	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	126	20	but	but	CC
cord-008530-yni0poh9	126	21	lacks	lack	VBZ
cord-008530-yni0poh9	126	22	the	the	DT
cord-008530-yni0poh9	126	23	ability	ability	NN
cord-008530-yni0poh9	126	24	to	to	TO
cord-008530-yni0poh9	126	25	further	further	RB
cord-008530-yni0poh9	126	26	activate	activate	VB
cord-008530-yni0poh9	126	27	these	these	DT
cord-008530-yni0poh9	126	28	cells	cell	NNS
cord-008530-yni0poh9	126	29	.	.	.
cord-008530-yni0poh9	127	1	Another	another	DT
cord-008530-yni0poh9	127	2	well	well	RB
cord-008530-yni0poh9	127	3	-	-	HYPH
cord-008530-yni0poh9	127	4	studied	study	VBN
cord-008530-yni0poh9	127	5	CC	cc	NN
cord-008530-yni0poh9	127	6	chemokine	chemokine	NN
cord-008530-yni0poh9	127	7	is	be	VBZ
cord-008530-yni0poh9	127	8	MIP	MIP	NNP
cord-008530-yni0poh9	127	9	-	-	HYPH
cord-008530-yni0poh9	127	10	la	la	NNP
cord-008530-yni0poh9	127	11	,	,	,
cord-008530-yni0poh9	127	12	which	which	WDT
cord-008530-yni0poh9	127	13	induces	induce	VBZ
cord-008530-yni0poh9	127	14	migration	migration	NN
cord-008530-yni0poh9	127	15	of	of	IN
cord-008530-yni0poh9	127	16	monocytes	monocyte	NNS
cord-008530-yni0poh9	127	17	,	,	,
cord-008530-yni0poh9	127	18	T	t	NN
cord-008530-yni0poh9	127	19	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	127	20	,	,	,
cord-008530-yni0poh9	127	21	and	and	CC
cord-008530-yni0poh9	127	22	eosinophils	eosinophil	NNS
cord-008530-yni0poh9	127	23	(	(	-LRB-
cord-008530-yni0poh9	127	24	Baggiolini	Baggiolini	NNP
cord-008530-yni0poh9	127	25	et	et	NNP
cord-008530-yni0poh9	127	26	al	al	NNP
cord-008530-yni0poh9	127	27	.	.	NNP
cord-008530-yni0poh9	127	28	,	,	,
cord-008530-yni0poh9	127	29	1994	1994	CD
cord-008530-yni0poh9	127	30	)	)	-RRB-
cord-008530-yni0poh9	127	31	.	.	.
cord-008530-yni0poh9	128	1	Mice	mouse	NNS
cord-008530-yni0poh9	128	2	with	with	IN
cord-008530-yni0poh9	128	3	a	a	DT
cord-008530-yni0poh9	128	4	targeted	target	VBN
cord-008530-yni0poh9	128	5	disruption	disruption	NN
cord-008530-yni0poh9	128	6	of	of	IN
cord-008530-yni0poh9	128	7	MIP	MIP	NNP
cord-008530-yni0poh9	128	8	-	-	HYPH
cord-008530-yni0poh9	128	9	la	la	NNP
cord-008530-yni0poh9	128	10	show	show	VBP
cord-008530-yni0poh9	128	11	no	no	DT
cord-008530-yni0poh9	128	12	obvious	obvious	JJ
cord-008530-yni0poh9	128	13	hematopoietic	hematopoietic	JJ
cord-008530-yni0poh9	128	14	abnormalities	abnormality	NNS
cord-008530-yni0poh9	128	15	;	;	:
cord-008530-yni0poh9	128	16	however	however	RB
cord-008530-yni0poh9	128	17	,	,	,
cord-008530-yni0poh9	128	18	they	-PRON-	PRP
cord-008530-yni0poh9	128	19	are	be	VBP
cord-008530-yni0poh9	128	20	resistant	resistant	JJ
cord-008530-yni0poh9	128	21	to	to	IN
cord-008530-yni0poh9	128	22	coxsackievirus	coxsackievirus	NN
cord-008530-yni0poh9	128	23	-	-	HYPH
cord-008530-yni0poh9	128	24	induced	induce	VBN
cord-008530-yni0poh9	128	25	myocarditis	myocarditis	NN
cord-008530-yni0poh9	128	26	and	and	CC
cord-008530-yni0poh9	128	27	clear	clear	JJ
cord-008530-yni0poh9	128	28	influenza	influenza	NN
cord-008530-yni0poh9	128	29	at	at	IN
cord-008530-yni0poh9	128	30	a	a	DT
cord-008530-yni0poh9	128	31	delayed	delay	VBN
cord-008530-yni0poh9	128	32	rate	rate	NN
cord-008530-yni0poh9	128	33	(	(	-LRB-
cord-008530-yni0poh9	128	34	Cook	Cook	NNP
cord-008530-yni0poh9	128	35	et	et	NNP
cord-008530-yni0poh9	128	36	al	al	NNP
cord-008530-yni0poh9	128	37	.	.	NNP
cord-008530-yni0poh9	128	38	,	,	,
cord-008530-yni0poh9	128	39	1995	1995	CD
cord-008530-yni0poh9	128	40	)	)	-RRB-
cord-008530-yni0poh9	128	41	.	.	.
cord-008530-yni0poh9	129	1	To	to	IN
cord-008530-yni0poh9	129	2	date	date	NN
cord-008530-yni0poh9	129	3	,	,	,
cord-008530-yni0poh9	129	4	9	9	CD
cord-008530-yni0poh9	129	5	CC	cc	NN
cord-008530-yni0poh9	129	6	receptors	receptor	NNS
cord-008530-yni0poh9	129	7	(	(	-LRB-
cord-008530-yni0poh9	129	8	CCR1-CCR9	CCR1-CCR9	NNP
cord-008530-yni0poh9	129	9	)	)	-RRB-
cord-008530-yni0poh9	129	10	have	have	VBP
cord-008530-yni0poh9	129	11	been	be	VBN
cord-008530-yni0poh9	129	12	identified	identify	VBN
cord-008530-yni0poh9	129	13	(	(	-LRB-
cord-008530-yni0poh9	129	14	Table	table	NN
cord-008530-yni0poh9	129	15	 	 	_SP
cord-008530-yni0poh9	129	16	I	i	NN
cord-008530-yni0poh9	129	17	)	)	-RRB-
cord-008530-yni0poh9	129	18	.	.	.
cord-008530-yni0poh9	130	1	CCR1	CCR1	NNP
cord-008530-yni0poh9	130	2	was	be	VBD
cord-008530-yni0poh9	130	3	originally	originally	RB
cord-008530-yni0poh9	130	4	designated	designate	VBN
cord-008530-yni0poh9	130	5	as	as	IN
cord-008530-yni0poh9	130	6	an	an	DT
cord-008530-yni0poh9	130	7	MIP	MIP	NNP
cord-008530-yni0poh9	130	8	-	-	HYPH
cord-008530-yni0poh9	130	9	la	la	NNP
cord-008530-yni0poh9	130	10	/	/	SYM
cord-008530-yni0poh9	130	11	RANTES	RANTES	NNP
cord-008530-yni0poh9	130	12	receptor	receptor	NN
cord-008530-yni0poh9	130	13	(	(	-LRB-
cord-008530-yni0poh9	130	14	Gao	Gao	NNP
cord-008530-yni0poh9	130	15	et	et	NNP
cord-008530-yni0poh9	130	16	al	al	NNP
cord-008530-yni0poh9	130	17	.	.	NNP
cord-008530-yni0poh9	130	18	,	,	,
cord-008530-yni0poh9	130	19	1993	1993	CD
cord-008530-yni0poh9	130	20	;	;	:
cord-008530-yni0poh9	130	21	Gao	Gao	NNP
cord-008530-yni0poh9	130	22	and	and	CC
cord-008530-yni0poh9	130	23	Murphy	Murphy	NNP
cord-008530-yni0poh9	130	24	,	,	,
cord-008530-yni0poh9	130	25	1995	1995	CD
cord-008530-yni0poh9	130	26	;	;	:
cord-008530-yni0poh9	130	27	Neote	Neote	NNP
cord-008530-yni0poh9	130	28	et	et	NNP
cord-008530-yni0poh9	130	29	al	al	NNP
cord-008530-yni0poh9	130	30	.	.	NNP
cord-008530-yni0poh9	130	31	,	,	,
cord-008530-yni0poh9	130	32	1993	1993	CD
cord-008530-yni0poh9	130	33	)	)	-RRB-
cord-008530-yni0poh9	130	34	and	and	CC
cord-008530-yni0poh9	130	35	was	be	VBD
cord-008530-yni0poh9	130	36	later	later	RB
cord-008530-yni0poh9	130	37	shown	show	VBN
cord-008530-yni0poh9	130	38	to	to	TO
cord-008530-yni0poh9	130	39	also	also	RB
cord-008530-yni0poh9	130	40	bind	bind	VB
cord-008530-yni0poh9	130	41	MCP-2	MCP-2	NNP
cord-008530-yni0poh9	130	42	and	and	CC
cord-008530-yni0poh9	131	1	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	131	2	(	(	-LRB-
cord-008530-yni0poh9	131	3	Ben-	Ben-	NFP
cord-008530-yni0poh9	131	4	Baruch	Baruch	NNP
cord-008530-yni0poh9	131	5	et	et	NNP
cord-008530-yni0poh9	131	6	al	al	NNP
cord-008530-yni0poh9	131	7	.	.	NNP
cord-008530-yni0poh9	131	8	,	,	,
cord-008530-yni0poh9	131	9	1995	1995	CD
cord-008530-yni0poh9	131	10	)	)	-RRB-
cord-008530-yni0poh9	131	11	.	.	.
cord-008530-yni0poh9	132	1	The	the	DT
cord-008530-yni0poh9	132	2	CCR1	CCR1	NNP
cord-008530-yni0poh9	132	3	receptor	receptor	NN
cord-008530-yni0poh9	132	4	is	be	VBZ
cord-008530-yni0poh9	132	5	mainly	mainly	RB
cord-008530-yni0poh9	132	6	found	find	VBN
cord-008530-yni0poh9	132	7	on	on	IN
cord-008530-yni0poh9	132	8	circulating	circulate	VBG
cord-008530-yni0poh9	132	9	mononuclear	mononuclear	JJ
cord-008530-yni0poh9	132	10	cells	cell	NNS
cord-008530-yni0poh9	132	11	.	.	.
cord-008530-yni0poh9	133	1	Mice	mouse	NNS
cord-008530-yni0poh9	133	2	lacking	lack	VBG
cord-008530-yni0poh9	133	3	CCR1	CCR1	NNP
cord-008530-yni0poh9	133	4	(	(	-LRB-
cord-008530-yni0poh9	133	5	receptor	receptor	NN
cord-008530-yni0poh9	133	6	for	for	IN
cord-008530-yni0poh9	133	7	MIP	MIP	NNP
cord-008530-yni0poh9	133	8	-	-	HYPH
cord-008530-yni0poh9	133	9	la	la	NNP
cord-008530-yni0poh9	133	10	,	,	,
cord-008530-yni0poh9	133	11	MIP-5	MIP-5	NNP
cord-008530-yni0poh9	133	12	,	,	,
cord-008530-yni0poh9	133	13	MCP-2	MCP-2	NNP
cord-008530-yni0poh9	133	14	,	,	,
cord-008530-yni0poh9	133	15	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	133	16	,	,	,
cord-008530-yni0poh9	133	17	and	and	CC
cord-008530-yni0poh9	133	18	RANTES	RANTES	NNP
cord-008530-yni0poh9	133	19	)	)	-RRB-
cord-008530-yni0poh9	133	20	have	have	VBP
cord-008530-yni0poh9	133	21	a	a	DT
cord-008530-yni0poh9	133	22	phenotype	phenotype	NN
cord-008530-yni0poh9	133	23	similar	similar	JJ
cord-008530-yni0poh9	133	24	to	to	IN
cord-008530-yni0poh9	133	25	that	that	DT
cord-008530-yni0poh9	133	26	of	of	IN
cord-008530-yni0poh9	133	27	MIP	MIP	NNP
cord-008530-yni0poh9	133	28	-	-	HYPH
cord-008530-yni0poh9	133	29	la	la	NNP
cord-008530-yni0poh9	133	30	deficient	deficient	JJ
cord-008530-yni0poh9	133	31	mice	mouse	NNS
cord-008530-yni0poh9	133	32	with	with	IN
cord-008530-yni0poh9	133	33	a	a	DT
cord-008530-yni0poh9	133	34	defect	defect	NN
cord-008530-yni0poh9	133	35	in	in	IN
cord-008530-yni0poh9	133	36	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	133	37	responses	response	NNS
cord-008530-yni0poh9	133	38	to	to	IN
cord-008530-yni0poh9	133	39	microbial	microbial	JJ
cord-008530-yni0poh9	133	40	challenge	challenge	NN
cord-008530-yni0poh9	133	41	such	such	JJ
cord-008530-yni0poh9	133	42	as	as	IN
cord-008530-yni0poh9	133	43	coxsackie	coxsackie	NNP
cord-008530-yni0poh9	133	44	B	B	NNP
cord-008530-yni0poh9	133	45	and	and	CC
cord-008530-yni0poh9	133	46	influenza	influenza	NN
cord-008530-yni0poh9	133	47	viruses	virus	NNS
cord-008530-yni0poh9	133	48	(	(	-LRB-
cord-008530-yni0poh9	133	49	Gao	Gao	NNP
cord-008530-yni0poh9	133	50	et	et	NNP
cord-008530-yni0poh9	133	51	al	al	NNP
cord-008530-yni0poh9	133	52	.	.	NNP
cord-008530-yni0poh9	133	53	,	,	,
cord-008530-yni0poh9	133	54	1997	1997	CD
cord-008530-yni0poh9	133	55	)	)	-RRB-
cord-008530-yni0poh9	133	56	.	.	.
cord-008530-yni0poh9	134	1	In	in	IN
cord-008530-yni0poh9	134	2	addition	addition	NN
cord-008530-yni0poh9	134	3	,	,	,
cord-008530-yni0poh9	134	4	these	these	DT
cord-008530-yni0poh9	134	5	animals	animal	NNS
cord-008530-yni0poh9	134	6	have	have	VBP
cord-008530-yni0poh9	134	7	impaired	impair	VBN
cord-008530-yni0poh9	134	8	trafficking	trafficking	NN
cord-008530-yni0poh9	134	9	of	of	IN
cord-008530-yni0poh9	134	10	subsets	subset	NNS
cord-008530-yni0poh9	134	11	of	of	IN
cord-008530-yni0poh9	134	12	myeloid	myeloid	JJ
cord-008530-yni0poh9	134	13	progenitor	progenitor	NN
cord-008530-yni0poh9	134	14	cells	cell	NNS
cord-008530-yni0poh9	134	15	.	.	.
cord-008530-yni0poh9	135	1	The	the	DT
cord-008530-yni0poh9	135	2	primary	primary	JJ
cord-008530-yni0poh9	135	3	receptor	receptor	NN
cord-008530-yni0poh9	135	4	for	for	IN
cord-008530-yni0poh9	135	5	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	135	6	,	,	,
cord-008530-yni0poh9	135	7	CCR2	CCR2	NNP
cord-008530-yni0poh9	135	8	,	,	,
cord-008530-yni0poh9	135	9	is	be	VBZ
cord-008530-yni0poh9	135	10	expressed	express	VBN
cord-008530-yni0poh9	135	11	on	on	IN
cord-008530-yni0poh9	135	12	monocytes	monocyte	NNS
cord-008530-yni0poh9	135	13	,	,	,
cord-008530-yni0poh9	135	14	myeloid	myeloid	JJ
cord-008530-yni0poh9	135	15	precursor	precursor	NN
cord-008530-yni0poh9	135	16	cells	cell	NNS
cord-008530-yni0poh9	135	17	,	,	,
cord-008530-yni0poh9	135	18	activated	activate	VBD
cord-008530-yni0poh9	135	19	T	t	NN
cord-008530-yni0poh9	135	20	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	135	21	,	,	,
cord-008530-yni0poh9	135	22	and	and	CC
cord-008530-yni0poh9	135	23	B	b	NN
cord-008530-yni0poh9	135	24	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	135	25	but	but	CC
cord-008530-yni0poh9	135	26	not	not	RB
cord-008530-yni0poh9	135	27	on	on	IN
cord-008530-yni0poh9	135	28	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	136	1	(	(	-LRB-
cord-008530-yni0poh9	136	2	Bonecchi	Bonecchi	NNP
cord-008530-yni0poh9	136	3	et	et	NNP
cord-008530-yni0poh9	136	4	al	al	NNP
cord-008530-yni0poh9	136	5	.	.	NNP
cord-008530-yni0poh9	136	6	,	,	,
cord-008530-yni0poh9	136	7	1999	1999	CD
cord-008530-yni0poh9	136	8	;	;	:
cord-008530-yni0poh9	136	9	Frade	Frade	NNP
cord-008530-yni0poh9	136	10	et	et	NNP
cord-008530-yni0poh9	136	11	al	al	NNP
cord-008530-yni0poh9	136	12	.	.	NNP
cord-008530-yni0poh9	136	13	,	,	,
cord-008530-yni0poh9	136	14	1997	1997	CD
cord-008530-yni0poh9	136	15	;	;	:
cord-008530-yni0poh9	136	16	Myers	Myers	NNP
cord-008530-yni0poh9	136	17	et	et	NNP
cord-008530-yni0poh9	136	18	al	al	NNP
cord-008530-yni0poh9	136	19	.	.	NNP
cord-008530-yni0poh9	136	20	,	,	,
cord-008530-yni0poh9	136	21	1995	1995	CD
cord-008530-yni0poh9	136	22	)	)	-RRB-
cord-008530-yni0poh9	136	23	.	.	.
cord-008530-yni0poh9	137	1	Mice	mouse	NNS
cord-008530-yni0poh9	137	2	with	with	IN
cord-008530-yni0poh9	137	3	targeted	target	VBN
cord-008530-yni0poh9	137	4	disruption	disruption	NN
cord-008530-yni0poh9	137	5	of	of	IN
cord-008530-yni0poh9	137	6	the	the	DT
cord-008530-yni0poh9	137	7	CCR2	CCR2	NNP
cord-008530-yni0poh9	137	8	receptor	receptor	NN
cord-008530-yni0poh9	137	9	have	have	VBP
cord-008530-yni0poh9	137	10	defects	defect	NNS
cord-008530-yni0poh9	137	11	in	in	IN
cord-008530-yni0poh9	137	12	monocyte	monocyte	NNP
cord-008530-yni0poh9	137	13	/	/	SYM
cord-008530-yni0poh9	137	14	macrophage	macrophage	NN
cord-008530-yni0poh9	137	15	recruitment	recruitment	NN
cord-008530-yni0poh9	137	16	in	in	IN
cord-008530-yni0poh9	137	17	a	a	DT
cord-008530-yni0poh9	137	18	variety	variety	NN
cord-008530-yni0poh9	137	19	of	of	IN
cord-008530-yni0poh9	137	20	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	137	21	and	and	CC
cord-008530-yni0poh9	137	22	immunological	immunological	JJ
cord-008530-yni0poh9	137	23	models	model	NNS
cord-008530-yni0poh9	137	24	(	(	-LRB-
cord-008530-yni0poh9	137	25	Boring	bore	VBG
cord-008530-yni0poh9	137	26	et	et	FW
cord-008530-yni0poh9	137	27	al	al	NNP
cord-008530-yni0poh9	137	28	.	.	NNP
cord-008530-yni0poh9	137	29	,	,	,
cord-008530-yni0poh9	137	30	1998	1998	CD
cord-008530-yni0poh9	137	31	;	;	:
cord-008530-yni0poh9	137	32	Kurihara	Kurihara	NNP
cord-008530-yni0poh9	137	33	et	et	NNP
cord-008530-yni0poh9	137	34	al	al	NNP
cord-008530-yni0poh9	137	35	.	.	NNP
cord-008530-yni0poh9	137	36	,	,	,
cord-008530-yni0poh9	137	37	1997	1997	CD
cord-008530-yni0poh9	137	38	;	;	:
cord-008530-yni0poh9	137	39	Kuziel	Kuziel	NNP
cord-008530-yni0poh9	137	40	et	et	NNP
cord-008530-yni0poh9	137	41	al	al	NNP
cord-008530-yni0poh9	137	42	.	.	NNP
cord-008530-yni0poh9	137	43	,	,	,
cord-008530-yni0poh9	137	44	1997	1997	CD
cord-008530-yni0poh9	137	45	)	)	-RRB-
cord-008530-yni0poh9	137	46	.	.	.
cord-008530-yni0poh9	138	1	CCR3	CCR3	NNP
cord-008530-yni0poh9	138	2	,	,	,
cord-008530-yni0poh9	138	3	which	which	WDT
cord-008530-yni0poh9	138	4	is	be	VBZ
cord-008530-yni0poh9	138	5	the	the	DT
cord-008530-yni0poh9	138	6	eotaxin	eotaxin	NNP
cord-008530-yni0poh9	138	7	receptor	receptor	NN
cord-008530-yni0poh9	138	8	,	,	,
cord-008530-yni0poh9	138	9	is	be	VBZ
cord-008530-yni0poh9	138	10	prominently	prominently	RB
cord-008530-yni0poh9	138	11	expressed	express	VBN
cord-008530-yni0poh9	138	12	by	by	IN
cord-008530-yni0poh9	138	13	eosinophils	eosinophil	NNS
cord-008530-yni0poh9	138	14	and	and	CC
cord-008530-yni0poh9	138	15	is	be	VBZ
cord-008530-yni0poh9	138	16	involved	involve	VBN
cord-008530-yni0poh9	138	17	in	in	IN
cord-008530-yni0poh9	138	18	the	the	DT
cord-008530-yni0poh9	138	19	recruitment	recruitment	NN
cord-008530-yni0poh9	138	20	of	of	IN
cord-008530-yni0poh9	138	21	these	these	DT
cord-008530-yni0poh9	138	22	cells	cell	NNS
cord-008530-yni0poh9	138	23	during	during	IN
cord-008530-yni0poh9	138	24	allergic	allergic	JJ
cord-008530-yni0poh9	138	25	reactions	reaction	NNS
cord-008530-yni0poh9	138	26	.	.	.
cord-008530-yni0poh9	139	1	CCR4	CCR4	NNP
cord-008530-yni0poh9	139	2	is	be	VBZ
cord-008530-yni0poh9	139	3	the	the	DT
cord-008530-yni0poh9	139	4	main	main	JJ
cord-008530-yni0poh9	139	5	receptor	receptor	NN
cord-008530-yni0poh9	139	6	for	for	IN
cord-008530-yni0poh9	139	7	RANTES	RANTES	NNPS
cord-008530-yni0poh9	139	8	and	and	CC
cord-008530-yni0poh9	139	9	MIP	MIP	NNP
cord-008530-yni0poh9	139	10	-	-	HYPH
cord-008530-yni0poh9	139	11	la	la	NNP
cord-008530-yni0poh9	139	12	,	,	,
cord-008530-yni0poh9	139	13	while	while	IN
cord-008530-yni0poh9	139	14	CCR5	CCR5	NNP
cord-008530-yni0poh9	139	15	,	,	,
cord-008530-yni0poh9	139	16	expressed	express	VBN
cord-008530-yni0poh9	139	17	on	on	IN
cord-008530-yni0poh9	139	18	monocytes	monocyte	NNS
cord-008530-yni0poh9	139	19	/	/	SYM
cord-008530-yni0poh9	139	20	macrophages	macrophage	NNS
cord-008530-yni0poh9	139	21	,	,	,
cord-008530-yni0poh9	139	22	T	t	NN
cord-008530-yni0poh9	139	23	cells	cell	NNS
cord-008530-yni0poh9	139	24	,	,	,
cord-008530-yni0poh9	139	25	and	and	CC
cord-008530-yni0poh9	139	26	granulocyte	granulocyte	NN
cord-008530-yni0poh9	139	27	precursors	precursor	NNS
cord-008530-yni0poh9	139	28	(	(	-LRB-
cord-008530-yni0poh9	140	1	Alkhatib	Alkhatib	NNP
cord-008530-yni0poh9	140	2	et	et	NNP
cord-008530-yni0poh9	140	3	al	al	NNP
cord-008530-yni0poh9	140	4	.	.	.
cord-008530-yni0poh9	141	1	,	,	,
cord-008530-yni0poh9	141	2	1996	1996	CD
cord-008530-yni0poh9	141	3	;	;	:
cord-008530-yni0poh9	141	4	Deng	Deng	NNP
cord-008530-yni0poh9	141	5	et	et	NNP
cord-008530-yni0poh9	141	6	al	al	NNP
cord-008530-yni0poh9	141	7	.	.	NNP
cord-008530-yni0poh9	141	8	,	,	,
cord-008530-yni0poh9	141	9	1996	1996	CD
cord-008530-yni0poh9	141	10	)	)	-RRB-
cord-008530-yni0poh9	141	11	,	,	,
cord-008530-yni0poh9	141	12	binds	bind	VBZ
cord-008530-yni0poh9	141	13	MIP	MIP	NNP
cord-008530-yni0poh9	141	14	-	-	HYPH
cord-008530-yni0poh9	141	15	la	la	NNP
cord-008530-yni0poh9	141	16	,	,	,
cord-008530-yni0poh9	141	17	MIP-1~	MIP-1~	NNP
cord-008530-yni0poh9	141	18	,	,	,
cord-008530-yni0poh9	141	19	and	and	CC
cord-008530-yni0poh9	141	20	RANTES	RANTES	NNP
cord-008530-yni0poh9	141	21	.	.	.
cord-008530-yni0poh9	142	1	The	the	DT
cord-008530-yni0poh9	142	2	receptors	receptor	NNS
cord-008530-yni0poh9	142	3	CCR6	CCR6	NNP
cord-008530-yni0poh9	142	4	and	and	CC
cord-008530-yni0poh9	142	5	CCR7	CCR7	NNP
cord-008530-yni0poh9	142	6	,	,	,
cord-008530-yni0poh9	142	7	originally	originally	RB
cord-008530-yni0poh9	142	8	identified	identify	VBN
cord-008530-yni0poh9	142	9	as	as	IN
cord-008530-yni0poh9	142	10	orphan	orphan	NN
cord-008530-yni0poh9	142	11	receptors	receptor	NNS
cord-008530-yni0poh9	142	12	,	,	,
cord-008530-yni0poh9	142	13	bind	bind	VBP
cord-008530-yni0poh9	142	14	MIP-3a	MIP-3a	NNP
cord-008530-yni0poh9	142	15	,	,	,
cord-008530-yni0poh9	142	16	and	and	CC
cord-008530-yni0poh9	142	17	MIP-3~	MIP-3~	NNS
cord-008530-yni0poh9	142	18	and	and	CC
cord-008530-yni0poh9	143	1	6Ckine	6Ckine	NNP
cord-008530-yni0poh9	143	2	respectively	respectively	RB
cord-008530-yni0poh9	143	3	Yoshida	Yoshida	NNP
cord-008530-yni0poh9	143	4	et	et	NNP
cord-008530-yni0poh9	143	5	al	al	NNP
cord-008530-yni0poh9	143	6	.	.	NNP
cord-008530-yni0poh9	143	7	,	,	,
cord-008530-yni0poh9	143	8	1997	1997	CD
cord-008530-yni0poh9	143	9	)	)	-RRB-
cord-008530-yni0poh9	143	10	.	.	.
cord-008530-yni0poh9	144	1	CCR8	CCR8	NNP
cord-008530-yni0poh9	144	2	binds	bind	VBZ
cord-008530-yni0poh9	144	3	1	1	CD
cord-008530-yni0poh9	144	4	-	-	SYM
cord-008530-yni0poh9	144	5	309	309	CD
cord-008530-yni0poh9	145	1	(	(	-LRB-
cord-008530-yni0poh9	145	2	Goya	Goya	NNP
cord-008530-yni0poh9	145	3	et	et	NNP
cord-008530-yni0poh9	145	4	al	al	NNP
cord-008530-yni0poh9	145	5	.	.	NNP
cord-008530-yni0poh9	145	6	,	,	,
cord-008530-yni0poh9	145	7	1998	1998	CD
cord-008530-yni0poh9	145	8	)	)	-RRB-
cord-008530-yni0poh9	145	9	,	,	,
cord-008530-yni0poh9	145	10	TARC	TARC	NNP
cord-008530-yni0poh9	145	11	,	,	,
cord-008530-yni0poh9	145	12	and	and	CC
cord-008530-yni0poh9	145	13	MIP	MIP	NNP
cord-008530-yni0poh9	145	14	-	-	HYPH
cord-008530-yni0poh9	145	15	I~	I~	NNP
cord-008530-yni0poh9	145	16	and	and	CC
cord-008530-yni0poh9	145	17	is	be	VBZ
cord-008530-yni0poh9	145	18	expressed	express	VBN
cord-008530-yni0poh9	145	19	in	in	IN
cord-008530-yni0poh9	145	20	the	the	DT
cord-008530-yni0poh9	145	21	thymus	thymus	NN
cord-008530-yni0poh9	145	22	(	(	-LRB-
cord-008530-yni0poh9	145	23	Zingoni	Zingoni	NNP
cord-008530-yni0poh9	145	24	et	et	FW
cord-008530-yni0poh9	145	25	al	al	NNP
cord-008530-yni0poh9	145	26	.	.	NNP
cord-008530-yni0poh9	145	27	,	,	,
cord-008530-yni0poh9	145	28	1998	1998	CD
cord-008530-yni0poh9	145	29	)	)	-RRB-
cord-008530-yni0poh9	145	30	.	.	.
cord-008530-yni0poh9	146	1	CCR9	CCR9	NNP
cord-008530-yni0poh9	146	2	,	,	,
cord-008530-yni0poh9	146	3	also	also	RB
cord-008530-yni0poh9	146	4	designated	designate	VBN
cord-008530-yni0poh9	146	5	as	as	IN
cord-008530-yni0poh9	146	6	GPR-9	GPR-9	NNP
cord-008530-yni0poh9	146	7	-	-	HYPH
cord-008530-yni0poh9	146	8	6	6	CD
cord-008530-yni0poh9	146	9	,	,	,
cord-008530-yni0poh9	146	10	was	be	VBD
cord-008530-yni0poh9	146	11	shown	show	VBN
cord-008530-yni0poh9	146	12	to	to	TO
cord-008530-yni0poh9	146	13	specifically	specifically	RB
cord-008530-yni0poh9	146	14	bind	bind	VB
cord-008530-yni0poh9	146	15	TECK	TECK	NNP
cord-008530-yni0poh9	146	16	(	(	-LRB-
cord-008530-yni0poh9	146	17	Zaballos	Zaballos	NNP
cord-008530-yni0poh9	146	18	et	et	NNP
cord-008530-yni0poh9	146	19	al	al	NNP
cord-008530-yni0poh9	146	20	.	.	NNP
cord-008530-yni0poh9	146	21	,	,	,
cord-008530-yni0poh9	146	22	1999	1999	CD
cord-008530-yni0poh9	146	23	)	)	-RRB-
cord-008530-yni0poh9	146	24	.	.	.
cord-008530-yni0poh9	147	1	Compartmentalization	compartmentalization	NN
cord-008530-yni0poh9	147	2	of	of	IN
cord-008530-yni0poh9	147	3	CC	CC	NNP
cord-008530-yni0poh9	147	4	chemokine	chemokine	NN
cord-008530-yni0poh9	147	5	receptor	receptor	NN
cord-008530-yni0poh9	147	6	expression	expression	NN
cord-008530-yni0poh9	147	7	is	be	VBZ
cord-008530-yni0poh9	147	8	emerging	emerge	VBG
cord-008530-yni0poh9	147	9	as	as	IN
cord-008530-yni0poh9	147	10	an	an	DT
cord-008530-yni0poh9	147	11	important	important	JJ
cord-008530-yni0poh9	147	12	regulatory	regulatory	JJ
cord-008530-yni0poh9	147	13	component	component	NN
cord-008530-yni0poh9	147	14	during	during	IN
cord-008530-yni0poh9	147	15	the	the	DT
cord-008530-yni0poh9	147	16	adaptive	adaptive	JJ
cord-008530-yni0poh9	147	17	immune	immune	JJ
cord-008530-yni0poh9	147	18	response	response	NN
cord-008530-yni0poh9	147	19	.	.	.
cord-008530-yni0poh9	148	1	CCR5	CCR5	NNP
cord-008530-yni0poh9	148	2	,	,	,
cord-008530-yni0poh9	148	3	the	the	DT
cord-008530-yni0poh9	148	4	receptor	receptor	NN
cord-008530-yni0poh9	148	5	for	for	IN
cord-008530-yni0poh9	148	6	RANTES	RANTES	NNP
cord-008530-yni0poh9	148	7	,	,	,
cord-008530-yni0poh9	148	8	MIP	MIP	NNP
cord-008530-yni0poh9	148	9	-	-	HYPH
cord-008530-yni0poh9	148	10	I~	I~	NNP
cord-008530-yni0poh9	148	11	,	,	,
cord-008530-yni0poh9	148	12	and	and	CC
cord-008530-yni0poh9	148	13	MIP-1~	MIP-1~	NNP
cord-008530-yni0poh9	148	14	is	be	VBZ
cord-008530-yni0poh9	148	15	expressed	express	VBN
cord-008530-yni0poh9	148	16	by	by	IN
cord-008530-yni0poh9	148	17	memory	memory	NN
cord-008530-yni0poh9	148	18	and	and	CC
cord-008530-yni0poh9	148	19	activated	activate	VBN
cord-008530-yni0poh9	148	20	T	t	NN
cord-008530-yni0poh9	148	21	cells	cell	NNS
cord-008530-yni0poh9	148	22	but	but	CC
cord-008530-yni0poh9	148	23	not	not	RB
cord-008530-yni0poh9	148	24	by	by	IN
cord-008530-yni0poh9	148	25	naive	naive	JJ
cord-008530-yni0poh9	148	26	T	t	NN
cord-008530-yni0poh9	148	27	cells	cell	NNS
cord-008530-yni0poh9	148	28	(	(	-LRB-
cord-008530-yni0poh9	149	1	Bleul	Bleul	NNP
cord-008530-yni0poh9	149	2	et	et	FW
cord-008530-yni0poh9	149	3	al	al	NNP
cord-008530-yni0poh9	149	4	.	.	NNP
cord-008530-yni0poh9	149	5	,	,	,
cord-008530-yni0poh9	149	6	1997	1997	CD
cord-008530-yni0poh9	149	7	)	)	-RRB-
cord-008530-yni0poh9	149	8	.	.	.
cord-008530-yni0poh9	150	1	Moreover	moreover	RB
cord-008530-yni0poh9	150	2	,	,	,
cord-008530-yni0poh9	150	3	CCR5	CCR5	NNP
cord-008530-yni0poh9	150	4	is	be	VBZ
cord-008530-yni0poh9	150	5	preferentially	preferentially	RB
cord-008530-yni0poh9	150	6	expressed	express	VBN
cord-008530-yni0poh9	150	7	by	by	IN
cord-008530-yni0poh9	150	8	human	human	JJ
cord-008530-yni0poh9	150	9	Thl	Thl	NNP
cord-008530-yni0poh9	150	10	cells	cell	NNS
cord-008530-yni0poh9	150	11	,	,	,
cord-008530-yni0poh9	150	12	in	in	IN
cord-008530-yni0poh9	150	13	contrast	contrast	NN
cord-008530-yni0poh9	150	14	to	to	IN
cord-008530-yni0poh9	150	15	CCR4	CCR4	NNP
cord-008530-yni0poh9	150	16	and	and	CC
cord-008530-yni0poh9	150	17	CCR3	CCR3	NNP
cord-008530-yni0poh9	150	18	,	,	,
cord-008530-yni0poh9	150	19	which	which	WDT
cord-008530-yni0poh9	150	20	are	be	VBP
cord-008530-yni0poh9	150	21	found	find	VBN
cord-008530-yni0poh9	150	22	predominantly	predominantly	RB
cord-008530-yni0poh9	150	23	on	on	IN
cord-008530-yni0poh9	150	24	Th2	th2	CD
cord-008530-yni0poh9	150	25	cells	cell	NNS
cord-008530-yni0poh9	150	26	(	(	-LRB-
cord-008530-yni0poh9	150	27	Bonecchi	Bonecchi	NNP
cord-008530-yni0poh9	150	28	et	et	NNP
cord-008530-yni0poh9	150	29	al	al	NNP
cord-008530-yni0poh9	150	30	.	.	NNP
cord-008530-yni0poh9	150	31	,	,	,
cord-008530-yni0poh9	150	32	1998	1998	CD
cord-008530-yni0poh9	150	33	;	;	:
cord-008530-yni0poh9	150	34	Qin	Qin	NNP
cord-008530-yni0poh9	150	35	et	et	FW
cord-008530-yni0poh9	150	36	al	al	NNP
cord-008530-yni0poh9	150	37	.	.	NNP
cord-008530-yni0poh9	150	38	,	,	,
cord-008530-yni0poh9	150	39	1998	1998	CD
cord-008530-yni0poh9	150	40	)	)	-RRB-
cord-008530-yni0poh9	150	41	.	.	.
cord-008530-yni0poh9	151	1	Concomitant	concomitant	JJ
cord-008530-yni0poh9	151	2	with	with	IN
cord-008530-yni0poh9	151	3	their	-PRON-	PRP$
cord-008530-yni0poh9	151	4	differential	differential	JJ
cord-008530-yni0poh9	151	5	chemokine	chemokine	NN
cord-008530-yni0poh9	151	6	receptor	receptor	NN
cord-008530-yni0poh9	151	7	expression	expression	NN
cord-008530-yni0poh9	151	8	,	,	,
cord-008530-yni0poh9	151	9	Thl	Thl	NNP
cord-008530-yni0poh9	151	10	and	and	CC
cord-008530-yni0poh9	151	11	Th2	th2	CD
cord-008530-yni0poh9	151	12	cells	cell	NNS
cord-008530-yni0poh9	151	13	selectively	selectively	RB
cord-008530-yni0poh9	151	14	migrate	migrate	VBP
cord-008530-yni0poh9	151	15	in	in	IN
cord-008530-yni0poh9	151	16	response	response	NN
cord-008530-yni0poh9	151	17	to	to	IN
cord-008530-yni0poh9	151	18	the	the	DT
cord-008530-yni0poh9	151	19	corresponding	corresponding	JJ
cord-008530-yni0poh9	151	20	chemokine	chemokine	NN
cord-008530-yni0poh9	151	21	ligand	ligand	NN
cord-008530-yni0poh9	151	22	.	.	.
cord-008530-yni0poh9	152	1	More	more	RBR
cord-008530-yni0poh9	152	2	recently	recently	RB
cord-008530-yni0poh9	152	3	,	,	,
cord-008530-yni0poh9	152	4	Sallusto	Sallusto	NNP
cord-008530-yni0poh9	152	5	et	et	FW
cord-008530-yni0poh9	152	6	al	al	NNP
cord-008530-yni0poh9	152	7	.	.	NNP
cord-008530-yni0poh9	152	8	showed	show	VBD
cord-008530-yni0poh9	152	9	that	that	IN
cord-008530-yni0poh9	152	10	memory	memory	NN
cord-008530-yni0poh9	152	11	T	t	NN
cord-008530-yni0poh9	152	12	cells	cell	NNS
cord-008530-yni0poh9	152	13	can	can	MD
cord-008530-yni0poh9	152	14	be	be	VB
cord-008530-yni0poh9	152	15	distinguished	distinguish	VBN
cord-008530-yni0poh9	152	16	with	with	IN
cord-008530-yni0poh9	152	17	respect	respect	NN
cord-008530-yni0poh9	152	18	to	to	IN
cord-008530-yni0poh9	152	19	their	-PRON-	PRP$
cord-008530-yni0poh9	152	20	effector	effector	NN
cord-008530-yni0poh9	152	21	function	function	NN
cord-008530-yni0poh9	152	22	in	in	IN
cord-008530-yni0poh9	152	23	peripheral	peripheral	JJ
cord-008530-yni0poh9	152	24	organs	organ	NNS
cord-008530-yni0poh9	152	25	by	by	IN
cord-008530-yni0poh9	152	26	their	-PRON-	PRP$
cord-008530-yni0poh9	152	27	expression	expression	NN
cord-008530-yni0poh9	152	28	of	of	IN
cord-008530-yni0poh9	152	29	the	the	DT
cord-008530-yni0poh9	152	30	chemokine	chemokine	NN
cord-008530-yni0poh9	152	31	receptor	receptor	NN
cord-008530-yni0poh9	152	32	CCR7	CCR7	NNP
cord-008530-yni0poh9	152	33	(	(	-LRB-
cord-008530-yni0poh9	152	34	Sallusto	Sallusto	NNP
cord-008530-yni0poh9	152	35	et	et	FW
cord-008530-yni0poh9	152	36	al	al	NNP
cord-008530-yni0poh9	152	37	.	.	NNP
cord-008530-yni0poh9	152	38	,	,	,
cord-008530-yni0poh9	152	39	1999b	1999b	CD
cord-008530-yni0poh9	152	40	)	)	-RRB-
cord-008530-yni0poh9	152	41	.	.	.
cord-008530-yni0poh9	153	1	CCR7	CCR7	NNP
cord-008530-yni0poh9	153	2	÷	÷	NNP
cord-008530-yni0poh9	153	3	memory	memory	NN
cord-008530-yni0poh9	153	4	T	t	NN
cord-008530-yni0poh9	153	5	cells	cell	NNS
cord-008530-yni0poh9	153	6	retain	retain	VBP
cord-008530-yni0poh9	153	7	lymph	lymph	NN
cord-008530-yni0poh9	153	8	node	node	NN
cord-008530-yni0poh9	153	9	homing	home	VBG
cord-008530-yni0poh9	153	10	receptors	receptor	NNS
cord-008530-yni0poh9	153	11	and	and	CC
cord-008530-yni0poh9	153	12	lack	lack	VBP
cord-008530-yni0poh9	153	13	immediate	immediate	JJ
cord-008530-yni0poh9	153	14	effector	effector	NN
cord-008530-yni0poh9	153	15	function	function	NN
cord-008530-yni0poh9	153	16	,	,	,
cord-008530-yni0poh9	153	17	whereas	whereas	IN
cord-008530-yni0poh9	153	18	CCR7memory	CCR7memory	NNP
cord-008530-yni0poh9	153	19	T	T	NNP
cord-008530-yni0poh9	153	20	cells	cell	NNS
cord-008530-yni0poh9	153	21	express	express	VBP
cord-008530-yni0poh9	153	22	receptors	receptor	NNS
cord-008530-yni0poh9	153	23	for	for	IN
cord-008530-yni0poh9	153	24	migration	migration	NN
cord-008530-yni0poh9	153	25	to	to	IN
cord-008530-yni0poh9	153	26	inflamed	inflamed	JJ
cord-008530-yni0poh9	153	27	tissues	tissue	NNS
cord-008530-yni0poh9	153	28	and	and	CC
cord-008530-yni0poh9	153	29	possess	possess	VB
cord-008530-yni0poh9	153	30	effector	effector	JJ
cord-008530-yni0poh9	153	31	function	function	NN
cord-008530-yni0poh9	153	32	.	.	.
cord-008530-yni0poh9	154	1	CCR8	CCR8	NNP
cord-008530-yni0poh9	154	2	,	,	,
cord-008530-yni0poh9	154	3	like	like	IN
cord-008530-yni0poh9	154	4	CCR4	CCR4	NNP
cord-008530-yni0poh9	155	1	(	(	-LRB-
cord-008530-yni0poh9	155	2	Bonecchi	Bonecchi	NNP
cord-008530-yni0poh9	155	3	et	et	NNP
cord-008530-yni0poh9	155	4	al	al	NNP
cord-008530-yni0poh9	155	5	.	.	NNP
cord-008530-yni0poh9	155	6	,	,	,
cord-008530-yni0poh9	155	7	1998	1998	CD
cord-008530-yni0poh9	155	8	)	)	-RRB-
cord-008530-yni0poh9	155	9	,	,	,
cord-008530-yni0poh9	155	10	is	be	VBZ
cord-008530-yni0poh9	155	11	preferentially	preferentially	RB
cord-008530-yni0poh9	155	12	expressed	express	VBN
cord-008530-yni0poh9	155	13	by	by	IN
cord-008530-yni0poh9	155	14	activated	activate	VBN
cord-008530-yni0poh9	155	15	Th2	th2	CD
cord-008530-yni0poh9	155	16	cells	cell	NNS
cord-008530-yni0poh9	155	17	.	.	.
cord-008530-yni0poh9	156	1	CCR8	CCR8	NNP
cord-008530-yni0poh9	156	2	may	may	MD
cord-008530-yni0poh9	156	3	be	be	VB
cord-008530-yni0poh9	156	4	important	important	JJ
cord-008530-yni0poh9	156	5	in	in	IN
cord-008530-yni0poh9	156	6	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	156	7	development	development	NN
cord-008530-yni0poh9	156	8	as	as	RB
cord-008530-yni0poh9	156	9	well	well	RB
cord-008530-yni0poh9	156	10	as	as	IN
cord-008530-yni0poh9	156	11	in	in	IN
cord-008530-yni0poh9	156	12	Th2-immune	th2-immune	DT
cord-008530-yni0poh9	156	13	responses	response	NNS
cord-008530-yni0poh9	156	14	.	.	.
cord-008530-yni0poh9	157	1	Polarized	polarized	JJ
cord-008530-yni0poh9	157	2	Th2	th2	CD
cord-008530-yni0poh9	157	3	cells	cell	NNS
cord-008530-yni0poh9	157	4	have	have	VBP
cord-008530-yni0poh9	157	5	been	be	VBN
cord-008530-yni0poh9	157	6	shown	show	VBN
cord-008530-yni0poh9	157	7	to	to	TO
cord-008530-yni0poh9	157	8	differentially	differentially	RB
cord-008530-yni0poh9	157	9	express	express	VB
cord-008530-yni0poh9	157	10	the	the	DT
cord-008530-yni0poh9	157	11	chemokine	chemokine	NN
cord-008530-yni0poh9	157	12	receptors	receptor	NNS
cord-008530-yni0poh9	157	13	,	,	,
cord-008530-yni0poh9	157	14	CCR8	CCR8	NNP
cord-008530-yni0poh9	157	15	(	(	-LRB-
cord-008530-yni0poh9	157	16	Zingoni	Zingoni	NNP
cord-008530-yni0poh9	157	17	et	et	FW
cord-008530-yni0poh9	157	18	al	al	NNP
cord-008530-yni0poh9	157	19	.	.	NNP
cord-008530-yni0poh9	157	20	,	,	,
cord-008530-yni0poh9	157	21	1998	1998	CD
cord-008530-yni0poh9	157	22	)	)	-RRB-
cord-008530-yni0poh9	157	23	,	,	,
cord-008530-yni0poh9	157	24	CCR4	CCR4	NNP
cord-008530-yni0poh9	157	25	(	(	-LRB-
cord-008530-yni0poh9	157	26	Bonecchi	Bonecchi	NNP
cord-008530-yni0poh9	157	27	et	et	NNP
cord-008530-yni0poh9	157	28	al	al	NNP
cord-008530-yni0poh9	157	29	.	.	NNP
cord-008530-yni0poh9	157	30	,	,	,
cord-008530-yni0poh9	157	31	1998	1998	CD
cord-008530-yni0poh9	157	32	;	;	:
cord-008530-yni0poh9	158	1	Sallusto	Sallusto	NNP
cord-008530-yni0poh9	158	2	et	et	FW
cord-008530-yni0poh9	158	3	al	al	NNP
cord-008530-yni0poh9	158	4	.	.	NNP
cord-008530-yni0poh9	158	5	,	,	,
cord-008530-yni0poh9	158	6	1999a	1999a	CD
cord-008530-yni0poh9	158	7	)	)	-RRB-
cord-008530-yni0poh9	159	1	and	and	CC
cord-008530-yni0poh9	159	2	CCR3	CCR3	NNP
cord-008530-yni0poh9	159	3	(	(	-LRB-
cord-008530-yni0poh9	159	4	Sallusto	Sallusto	NNP
cord-008530-yni0poh9	159	5	et	et	FW
cord-008530-yni0poh9	159	6	al	al	NNP
cord-008530-yni0poh9	159	7	.	.	NNP
cord-008530-yni0poh9	159	8	,	,	,
cord-008530-yni0poh9	159	9	1997	1997	CD
cord-008530-yni0poh9	159	10	)	)	-RRB-
cord-008530-yni0poh9	159	11	.	.	.
cord-008530-yni0poh9	160	1	In	in	IN
cord-008530-yni0poh9	160	2	the	the	DT
cord-008530-yni0poh9	160	3	murine	murine	JJ
cord-008530-yni0poh9	160	4	system	system	NN
cord-008530-yni0poh9	160	5	,	,	,
cord-008530-yni0poh9	160	6	a	a	DT
cord-008530-yni0poh9	160	7	recent	recent	JJ
cord-008530-yni0poh9	160	8	study	study	NN
cord-008530-yni0poh9	160	9	showed	show	VBD
cord-008530-yni0poh9	160	10	that	that	IN
cord-008530-yni0poh9	160	11	Thl	Thl	NNP
cord-008530-yni0poh9	160	12	and	and	CC
cord-008530-yni0poh9	160	13	Th2	th2	CD
cord-008530-yni0poh9	160	14	cells	cell	NNS
cord-008530-yni0poh9	160	15	expressed	express	VBD
cord-008530-yni0poh9	160	16	comparable	comparable	JJ
cord-008530-yni0poh9	160	17	levels	level	NNS
cord-008530-yni0poh9	160	18	of	of	IN
cord-008530-yni0poh9	160	19	CCR1	CCR1	NNP
cord-008530-yni0poh9	160	20	,	,	,
cord-008530-yni0poh9	160	21	CCR2	CCR2	NNP
cord-008530-yni0poh9	160	22	,	,	,
cord-008530-yni0poh9	160	23	and	and	CC
cord-008530-yni0poh9	160	24	CCR4	CCR4	NNP
cord-008530-yni0poh9	160	25	mRNA	mRNA	NNP
cord-008530-yni0poh9	160	26	.	.	.
cord-008530-yni0poh9	161	1	Similar	similar	JJ
cord-008530-yni0poh9	161	2	to	to	IN
cord-008530-yni0poh9	161	3	human	human	JJ
cord-008530-yni0poh9	161	4	T	T	NNP
cord-008530-yni0poh9	161	5	helper	helper	NN
cord-008530-yni0poh9	161	6	cells	cell	NNS
cord-008530-yni0poh9	161	7	,	,	,
cord-008530-yni0poh9	161	8	murine	murine	JJ
cord-008530-yni0poh9	161	9	Thl	Thl	NNP
cord-008530-yni0poh9	161	10	cells	cell	NNS
cord-008530-yni0poh9	161	11	preferentially	preferentially	RB
cord-008530-yni0poh9	161	12	expressed	express	VBD
cord-008530-yni0poh9	161	13	CCR7	CCR7	NNP
cord-008530-yni0poh9	161	14	and	and	CC
cord-008530-yni0poh9	161	15	CCR5	CCR5	NNP
cord-008530-yni0poh9	161	16	,	,	,
cord-008530-yni0poh9	161	17	whereas	whereas	IN
cord-008530-yni0poh9	161	18	Th2	th2	CD
cord-008530-yni0poh9	161	19	cells	cell	NNS
cord-008530-yni0poh9	161	20	expressed	express	VBD
cord-008530-yni0poh9	161	21	more	more	JJR
cord-008530-yni0poh9	161	22	CCR3	CCR3	NNP
cord-008530-yni0poh9	161	23	(	(	-LRB-
cord-008530-yni0poh9	161	24	Randolph	Randolph	NNP
cord-008530-yni0poh9	161	25	et	et	NNP
cord-008530-yni0poh9	161	26	al	al	NNP
cord-008530-yni0poh9	161	27	.	.	NNP
cord-008530-yni0poh9	161	28	,	,	,
cord-008530-yni0poh9	161	29	1999	1999	CD
cord-008530-yni0poh9	161	30	)	)	-RRB-
cord-008530-yni0poh9	161	31	.	.	.
cord-008530-yni0poh9	162	1	In	in	IN
cord-008530-yni0poh9	162	2	conclusion	conclusion	NN
cord-008530-yni0poh9	162	3	,	,	,
cord-008530-yni0poh9	162	4	depending	depend	VBG
cord-008530-yni0poh9	162	5	on	on	IN
cord-008530-yni0poh9	162	6	their	-PRON-	PRP$
cord-008530-yni0poh9	162	7	antigenic	antigenic	JJ
cord-008530-yni0poh9	162	8	stimulation	stimulation	NN
cord-008530-yni0poh9	162	9	and/or	and/or	CC
cord-008530-yni0poh9	162	10	polarization	polarization	NN
cord-008530-yni0poh9	162	11	toward	toward	IN
cord-008530-yni0poh9	162	12	Thl	Thl	NNP
cord-008530-yni0poh9	162	13	versus	versus	IN
cord-008530-yni0poh9	162	14	Th2	th2	CD
cord-008530-yni0poh9	162	15	subsets	subset	NNS
cord-008530-yni0poh9	162	16	,	,	,
cord-008530-yni0poh9	162	17	chemokine	chemokine	NN
cord-008530-yni0poh9	162	18	receptors	receptor	NNS
cord-008530-yni0poh9	162	19	are	be	VBP
cord-008530-yni0poh9	162	20	differentially	differentially	RB
cord-008530-yni0poh9	162	21	expressed	express	VBN
cord-008530-yni0poh9	162	22	,	,	,
cord-008530-yni0poh9	162	23	which	which	WDT
cord-008530-yni0poh9	162	24	,	,	,
cord-008530-yni0poh9	162	25	in	in	IN
cord-008530-yni0poh9	162	26	addition	addition	NN
cord-008530-yni0poh9	162	27	to	to	IN
cord-008530-yni0poh9	162	28	their	-PRON-	PRP$
cord-008530-yni0poh9	162	29	characteristic	characteristic	JJ
cord-008530-yni0poh9	162	30	cytokine	cytokine	NN
cord-008530-yni0poh9	162	31	profiles	profile	NNS
cord-008530-yni0poh9	162	32	,	,	,
cord-008530-yni0poh9	162	33	may	may	MD
cord-008530-yni0poh9	162	34	thus	thus	RB
cord-008530-yni0poh9	162	35	further	far	RBR
cord-008530-yni0poh9	162	36	distinguish	distinguish	VB
cord-008530-yni0poh9	162	37	these	these	DT
cord-008530-yni0poh9	162	38	cells	cell	NNS
cord-008530-yni0poh9	162	39	(	(	-LRB-
cord-008530-yni0poh9	162	40	Mantovani	Mantovani	NNP
cord-008530-yni0poh9	162	41	,	,	,
cord-008530-yni0poh9	162	42	1999b	1999b	CD
cord-008530-yni0poh9	162	43	)	)	-RRB-
cord-008530-yni0poh9	162	44	.	.	.
cord-008530-yni0poh9	163	1	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	163	2	,	,	,
cord-008530-yni0poh9	163	3	the	the	DT
cord-008530-yni0poh9	163	4	lone	lone	JJ
cord-008530-yni0poh9	163	5	member	member	NN
cord-008530-yni0poh9	163	6	of	of	IN
cord-008530-yni0poh9	163	7	the	the	DT
cord-008530-yni0poh9	163	8	C	C	NNP
cord-008530-yni0poh9	163	9	-	-	HYPH
cord-008530-yni0poh9	163	10	chemokine	chemokine	NN
cord-008530-yni0poh9	163	11	family	family	NN
cord-008530-yni0poh9	163	12	,	,	,
cord-008530-yni0poh9	163	13	is	be	VBZ
cord-008530-yni0poh9	163	14	produced	produce	VBN
cord-008530-yni0poh9	163	15	by	by	IN
cord-008530-yni0poh9	163	16	activated	activate	VBN
cord-008530-yni0poh9	163	17	mouse	mouse	NN
cord-008530-yni0poh9	163	18	T	T	NNP
cord-008530-yni0poh9	163	19	cells	cell	NNS
cord-008530-yni0poh9	163	20	(	(	-LRB-
cord-008530-yni0poh9	163	21	Kelner	Kelner	NNP
cord-008530-yni0poh9	163	22	et	et	FW
cord-008530-yni0poh9	163	23	al	al	NNP
cord-008530-yni0poh9	163	24	.	.	NNP
cord-008530-yni0poh9	163	25	,	,	,
cord-008530-yni0poh9	163	26	1994	1994	CD
cord-008530-yni0poh9	163	27	)	)	-RRB-
cord-008530-yni0poh9	163	28	.	.	.
cord-008530-yni0poh9	164	1	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	164	2	is	be	VBZ
cord-008530-yni0poh9	164	3	unique	unique	JJ
cord-008530-yni0poh9	164	4	because	because	IN
cord-008530-yni0poh9	164	5	(	(	-LRB-
cord-008530-yni0poh9	164	6	1	1	LS
cord-008530-yni0poh9	164	7	)	)	-RRB-
cord-008530-yni0poh9	164	8	it	-PRON-	PRP
cord-008530-yni0poh9	164	9	has	have	VBZ
cord-008530-yni0poh9	164	10	only	only	RB
cord-008530-yni0poh9	164	11	two	two	CD
cord-008530-yni0poh9	164	12	cysteines	cysteine	NNS
cord-008530-yni0poh9	164	13	,	,	,
cord-008530-yni0poh9	164	14	the	the	DT
cord-008530-yni0poh9	164	15	second	second	JJ
cord-008530-yni0poh9	164	16	and	and	CC
cord-008530-yni0poh9	164	17	the	the	DT
cord-008530-yni0poh9	164	18	fourth	fourth	JJ
cord-008530-yni0poh9	164	19	,	,	,
cord-008530-yni0poh9	164	20	of	of	IN
cord-008530-yni0poh9	164	21	the	the	DT
cord-008530-yni0poh9	164	22	four	four	CD
cord-008530-yni0poh9	164	23	cysteines	cysteine	NNS
cord-008530-yni0poh9	164	24	conserved	conserve	VBN
cord-008530-yni0poh9	164	25	in	in	IN
cord-008530-yni0poh9	164	26	the	the	DT
cord-008530-yni0poh9	164	27	CXC	CXC	NNP
cord-008530-yni0poh9	164	28	,	,	,
cord-008530-yni0poh9	164	29	CC	CC	NNP
cord-008530-yni0poh9	164	30	,	,	,
cord-008530-yni0poh9	164	31	and	and	CC
cord-008530-yni0poh9	164	32	CX3C	CX3C	NNS
cord-008530-yni0poh9	164	33	chemokines	chemokine	NNS
cord-008530-yni0poh9	164	34	;	;	:
cord-008530-yni0poh9	164	35	and	and	CC
cord-008530-yni0poh9	164	36	(	(	-LRB-
cord-008530-yni0poh9	164	37	2	2	LS
cord-008530-yni0poh9	164	38	)	)	-RRB-
cord-008530-yni0poh9	164	39	the	the	DT
cord-008530-yni0poh9	164	40	C	c	NN
cord-008530-yni0poh9	164	41	-	-	HYPH
cord-008530-yni0poh9	164	42	terminal	terminal	NN
cord-008530-yni0poh9	164	43	sequence	sequence	NN
cord-008530-yni0poh9	164	44	is	be	VBZ
cord-008530-yni0poh9	164	45	much	much	RB
cord-008530-yni0poh9	164	46	longer	long	JJR
cord-008530-yni0poh9	164	47	than	than	IN
cord-008530-yni0poh9	164	48	those	those	DT
cord-008530-yni0poh9	164	49	of	of	IN
cord-008530-yni0poh9	164	50	other	other	JJ
cord-008530-yni0poh9	164	51	chemokines	chemokine	NNS
cord-008530-yni0poh9	164	52	.	.	.
cord-008530-yni0poh9	165	1	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	165	2	,	,	,
cord-008530-yni0poh9	165	3	and	and	CC
cord-008530-yni0poh9	165	4	the	the	DT
cord-008530-yni0poh9	165	5	subsequently	subsequently	RB
cord-008530-yni0poh9	165	6	reported	report	VBN
cord-008530-yni0poh9	165	7	single	single	JJ
cord-008530-yni0poh9	165	8	motif	motif	NN
cord-008530-yni0poh9	165	9	cysteine	cysteine	NN
cord-008530-yni0poh9	165	10	(	(	-LRB-
cord-008530-yni0poh9	165	11	SMC	SMC	NNP
cord-008530-yni0poh9	165	12	)	)	-RRB-
cord-008530-yni0poh9	165	13	chemokine-1	chemokine-1	NNP
cord-008530-yni0poh9	165	14	and	and	CC
cord-008530-yni0poh9	165	15	the	the	DT
cord-008530-yni0poh9	165	16	activation	activation	NN
cord-008530-yni0poh9	165	17	-	-	HYPH
cord-008530-yni0poh9	165	18	induced	induce	VBN
cord-008530-yni0poh9	165	19	,	,	,
cord-008530-yni0poh9	165	20	T	t	NN
cord-008530-yni0poh9	165	21	-	-	HYPH
cord-008530-yni0poh9	165	22	cell	cell	NN
cord-008530-yni0poh9	165	23	-	-	HYPH
cord-008530-yni0poh9	165	24	derived	derive	VBN
cord-008530-yni0poh9	165	25	,	,	,
cord-008530-yni0poh9	165	26	and	and	CC
cord-008530-yni0poh9	165	27	chemokine	chemokine	NN
cord-008530-yni0poh9	165	28	-	-	HYPH
cord-008530-yni0poh9	165	29	related	relate	VBN
cord-008530-yni0poh9	165	30	molecule	molecule	NN
cord-008530-yni0poh9	165	31	(	(	-LRB-
cord-008530-yni0poh9	165	32	ATAC	ATAC	NNP
cord-008530-yni0poh9	165	33	)	)	-RRB-
cord-008530-yni0poh9	165	34	,	,	,
cord-008530-yni0poh9	165	35	are	be	VBP
cord-008530-yni0poh9	165	36	all	all	DT
cord-008530-yni0poh9	165	37	identical	identical	JJ
cord-008530-yni0poh9	166	1	(	(	-LRB-
cord-008530-yni0poh9	166	2	Muller	Muller	NNP
cord-008530-yni0poh9	166	3	et	et	NNP
cord-008530-yni0poh9	166	4	al	al	NNP
cord-008530-yni0poh9	166	5	.	.	NNP
cord-008530-yni0poh9	166	6	,	,	,
cord-008530-yni0poh9	166	7	1995	1995	CD
cord-008530-yni0poh9	166	8	;	;	:
cord-008530-yni0poh9	166	9	Yoshida	Yoshida	NNP
cord-008530-yni0poh9	166	10	et	et	NNP
cord-008530-yni0poh9	166	11	al	al	NNP
cord-008530-yni0poh9	166	12	.	.	NNP
cord-008530-yni0poh9	166	13	,	,	,
cord-008530-yni0poh9	166	14	1995	1995	CD
cord-008530-yni0poh9	166	15	)	)	-RRB-
cord-008530-yni0poh9	166	16	.	.	.
cord-008530-yni0poh9	167	1	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	167	2	expression	expression	NN
cord-008530-yni0poh9	167	3	on	on	IN
cord-008530-yni0poh9	167	4	activation	activation	NN
cord-008530-yni0poh9	167	5	is	be	VBZ
cord-008530-yni0poh9	167	6	extremely	extremely	RB
cord-008530-yni0poh9	167	7	rapid	rapid	JJ
cord-008530-yni0poh9	167	8	,	,	,
cord-008530-yni0poh9	167	9	which	which	WDT
cord-008530-yni0poh9	167	10	suggests	suggest	VBZ
cord-008530-yni0poh9	167	11	that	that	IN
cord-008530-yni0poh9	167	12	it	-PRON-	PRP
cord-008530-yni0poh9	167	13	has	have	VBZ
cord-008530-yni0poh9	167	14	a	a	DT
cord-008530-yni0poh9	167	15	role	role	NN
cord-008530-yni0poh9	167	16	in	in	IN
cord-008530-yni0poh9	167	17	the	the	DT
cord-008530-yni0poh9	167	18	early	early	JJ
cord-008530-yni0poh9	167	19	phases	phase	NNS
cord-008530-yni0poh9	167	20	of	of	IN
cord-008530-yni0poh9	167	21	an	an	DT
cord-008530-yni0poh9	167	22	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	167	23	response	response	NN
cord-008530-yni0poh9	167	24	.	.	.
cord-008530-yni0poh9	168	1	When	when	WRB
cord-008530-yni0poh9	168	2	lymphotactin	lymphotactin	NNP
cord-008530-yni0poh9	168	3	is	be	VBZ
cord-008530-yni0poh9	168	4	injected	inject	VBN
cord-008530-yni0poh9	168	5	into	into	IN
cord-008530-yni0poh9	168	6	peritoneum	peritoneum	NN
cord-008530-yni0poh9	168	7	,	,	,
cord-008530-yni0poh9	168	8	it	-PRON-	PRP
cord-008530-yni0poh9	168	9	causes	cause	VBZ
cord-008530-yni0poh9	168	10	an	an	DT
cord-008530-yni0poh9	168	11	influx	influx	NN
cord-008530-yni0poh9	168	12	of	of	IN
cord-008530-yni0poh9	168	13	T	t	NN
cord-008530-yni0poh9	168	14	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	168	15	and	and	CC
cord-008530-yni0poh9	168	16	NK	NK	NNP
cord-008530-yni0poh9	168	17	cells	cell	NNS
cord-008530-yni0poh9	168	18	by	by	IN
cord-008530-yni0poh9	168	19	24h	24h	NNS
cord-008530-yni0poh9	169	1	(	(	-LRB-
cord-008530-yni0poh9	169	2	Hedrick	Hedrick	NNP
cord-008530-yni0poh9	169	3	et	et	NNP
cord-008530-yni0poh9	169	4	al	al	NNP
cord-008530-yni0poh9	169	5	.	.	NNP
cord-008530-yni0poh9	169	6	,	,	,
cord-008530-yni0poh9	169	7	1997	1997	CD
cord-008530-yni0poh9	169	8	)	)	-RRB-
cord-008530-yni0poh9	169	9	.	.	.
cord-008530-yni0poh9	170	1	Yoshida	Yoshida	NNP
cord-008530-yni0poh9	170	2	et	et	NNP
cord-008530-yni0poh9	170	3	al	al	NNP
cord-008530-yni0poh9	170	4	.	.	.
cord-008530-yni0poh9	171	1	(	(	-LRB-
cord-008530-yni0poh9	171	2	1998	1998	CD
cord-008530-yni0poh9	171	3	)	)	-RRB-
cord-008530-yni0poh9	171	4	identified	identify	VBD
cord-008530-yni0poh9	171	5	an	an	DT
cord-008530-yni0poh9	171	6	orphan	orphan	NN
cord-008530-yni0poh9	171	7	receptor	receptor	NN
cord-008530-yni0poh9	171	8	,	,	,
cord-008530-yni0poh9	171	9	GPR5	GPR5	NNP
cord-008530-yni0poh9	171	10	(	(	-LRB-
cord-008530-yni0poh9	171	11	Heiber	Heiber	NNP
cord-008530-yni0poh9	171	12	et	et	FW
cord-008530-yni0poh9	171	13	al	al	NNP
cord-008530-yni0poh9	171	14	.	.	NNP
cord-008530-yni0poh9	171	15	,	,	,
cord-008530-yni0poh9	171	16	1995	1995	CD
cord-008530-yni0poh9	171	17	)	)	-RRB-
cord-008530-yni0poh9	171	18	,	,	,
cord-008530-yni0poh9	171	19	as	as	IN
cord-008530-yni0poh9	171	20	being	be	VBG
cord-008530-yni0poh9	171	21	a	a	DT
cord-008530-yni0poh9	171	22	high	high	JJ
cord-008530-yni0poh9	171	23	-	-	HYPH
cord-008530-yni0poh9	171	24	affinity	affinity	NN
cord-008530-yni0poh9	171	25	functional	functional	JJ
cord-008530-yni0poh9	171	26	receptor	receptor	NN
cord-008530-yni0poh9	171	27	for	for	IN
cord-008530-yni0poh9	171	28	lymphotactin	lymphotactin	NNP
cord-008530-yni0poh9	171	29	this	this	DT
cord-008530-yni0poh9	171	30	receptor	receptor	NN
cord-008530-yni0poh9	171	31	was	be	VBD
cord-008530-yni0poh9	171	32	renamed	rename	VBN
cord-008530-yni0poh9	171	33	XCR1	XCR1	NNP
cord-008530-yni0poh9	171	34	.	.	.
cord-008530-yni0poh9	172	1	The	the	DT
cord-008530-yni0poh9	172	2	single	single	JJ
cord-008530-yni0poh9	172	3	member	member	NN
cord-008530-yni0poh9	172	4	of	of	IN
cord-008530-yni0poh9	172	5	the	the	DT
cord-008530-yni0poh9	172	6	CX3C	CX3C	NNS
cord-008530-yni0poh9	172	7	or	or	CC
cord-008530-yni0poh9	172	8	8	8	CD
cord-008530-yni0poh9	172	9	family	family	NN
cord-008530-yni0poh9	172	10	,	,	,
cord-008530-yni0poh9	172	11	named	name	VBN
cord-008530-yni0poh9	172	12	fractalkine	fractalkine	NNP
cord-008530-yni0poh9	172	13	,	,	,
cord-008530-yni0poh9	172	14	is	be	VBZ
cord-008530-yni0poh9	172	15	also	also	RB
cord-008530-yni0poh9	172	16	unique	unique	JJ
cord-008530-yni0poh9	172	17	with	with	IN
cord-008530-yni0poh9	172	18	a	a	DT
cord-008530-yni0poh9	172	19	novel	novel	JJ
cord-008530-yni0poh9	172	20	arrangement	arrangement	NN
cord-008530-yni0poh9	172	21	of	of	IN
cord-008530-yni0poh9	172	22	three	three	CD
cord-008530-yni0poh9	172	23	amino	amino	NN
cord-008530-yni0poh9	172	24	acids	acid	NNS
cord-008530-yni0poh9	172	25	separating	separate	VBG
cord-008530-yni0poh9	172	26	the	the	DT
cord-008530-yni0poh9	172	27	first	first	JJ
cord-008530-yni0poh9	172	28	two	two	CD
cord-008530-yni0poh9	172	29	conserved	conserved	JJ
cord-008530-yni0poh9	172	30	cysteines	cysteine	NNS
cord-008530-yni0poh9	172	31	.	.	.
cord-008530-yni0poh9	173	1	Furthermore	furthermore	RB
cord-008530-yni0poh9	173	2	,	,	,
cord-008530-yni0poh9	173	3	fractalkine	fractalkine	NN
cord-008530-yni0poh9	173	4	exists	exist	VBZ
cord-008530-yni0poh9	173	5	in	in	IN
cord-008530-yni0poh9	173	6	both	both	CC
cord-008530-yni0poh9	173	7	soluble	soluble	JJ
cord-008530-yni0poh9	173	8	and	and	CC
cord-008530-yni0poh9	173	9	membrane	membrane	NN
cord-008530-yni0poh9	173	10	-	-	HYPH
cord-008530-yni0poh9	173	11	bound	bind	VBN
cord-008530-yni0poh9	173	12	forms	form	NNS
cord-008530-yni0poh9	173	13	(	(	-LRB-
cord-008530-yni0poh9	173	14	Bazan	Bazan	NNP
cord-008530-yni0poh9	173	15	et	et	NNP
cord-008530-yni0poh9	173	16	al	al	NNP
cord-008530-yni0poh9	173	17	.	.	NNP
cord-008530-yni0poh9	173	18	,	,	,
cord-008530-yni0poh9	173	19	1997	1997	CD
cord-008530-yni0poh9	173	20	;	;	:
cord-008530-yni0poh9	173	21	Pan	Pan	NNP
cord-008530-yni0poh9	173	22	et	et	NNP
cord-008530-yni0poh9	173	23	al	al	NNP
cord-008530-yni0poh9	173	24	.	.	NNP
cord-008530-yni0poh9	173	25	,	,	,
cord-008530-yni0poh9	173	26	1997	1997	CD
cord-008530-yni0poh9	173	27	)	)	-RRB-
cord-008530-yni0poh9	173	28	.	.	.
cord-008530-yni0poh9	174	1	This	this	DT
cord-008530-yni0poh9	174	2	chemokine	chemokine	NN
cord-008530-yni0poh9	174	3	is	be	VBZ
cord-008530-yni0poh9	174	4	found	find	VBN
cord-008530-yni0poh9	174	5	on	on	IN
cord-008530-yni0poh9	174	6	activated	activate	VBN
cord-008530-yni0poh9	174	7	endothelial	endothelial	JJ
cord-008530-yni0poh9	174	8	cells	cell	NNS
cord-008530-yni0poh9	174	9	and	and	CC
cord-008530-yni0poh9	174	10	is	be	VBZ
cord-008530-yni0poh9	174	11	tethered	tether	VBN
cord-008530-yni0poh9	174	12	to	to	IN
cord-008530-yni0poh9	174	13	the	the	DT
cord-008530-yni0poh9	174	14	membrane	membrane	NN
cord-008530-yni0poh9	174	15	by	by	IN
cord-008530-yni0poh9	174	16	a	a	DT
cord-008530-yni0poh9	174	17	mucinlike	mucinlike	NN
cord-008530-yni0poh9	174	18	stalk	stalk	NN
cord-008530-yni0poh9	174	19	that	that	WDT
cord-008530-yni0poh9	174	20	suggests	suggest	VBZ
cord-008530-yni0poh9	174	21	a	a	DT
cord-008530-yni0poh9	174	22	novel	novel	JJ
cord-008530-yni0poh9	174	23	role	role	NN
cord-008530-yni0poh9	174	24	for	for	IN
cord-008530-yni0poh9	174	25	this	this	DT
cord-008530-yni0poh9	174	26	chemokine	chemokine	NN
cord-008530-yni0poh9	174	27	in	in	IN
cord-008530-yni0poh9	174	28	juxtacrine	juxtacrine	NNP
cord-008530-yni0poh9	174	29	signaling	signal	VBG
cord-008530-yni0poh9	174	30	.	.	.
cord-008530-yni0poh9	175	1	The	the	DT
cord-008530-yni0poh9	175	2	interaction	interaction	NN
cord-008530-yni0poh9	175	3	of	of	IN
cord-008530-yni0poh9	175	4	endothelial	endothelial	JJ
cord-008530-yni0poh9	175	5	-	-	HYPH
cord-008530-yni0poh9	175	6	cell	cell	NN
cord-008530-yni0poh9	175	7	-	-	HYPH
cord-008530-yni0poh9	175	8	expressed	express	VBN
cord-008530-yni0poh9	175	9	fractalkine	fractalkine	NN
cord-008530-yni0poh9	175	10	with	with	IN
cord-008530-yni0poh9	175	11	its	-PRON-	PRP$
cord-008530-yni0poh9	175	12	receptor	receptor	NN
cord-008530-yni0poh9	175	13	,	,	,
cord-008530-yni0poh9	175	14	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	175	15	,	,	,
cord-008530-yni0poh9	175	16	on	on	IN
cord-008530-yni0poh9	175	17	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	175	18	mediates	mediate	VBZ
cord-008530-yni0poh9	175	19	the	the	DT
cord-008530-yni0poh9	175	20	initial	initial	JJ
cord-008530-yni0poh9	175	21	capture	capture	NN
cord-008530-yni0poh9	175	22	,	,	,
cord-008530-yni0poh9	175	23	firm	firm	JJ
cord-008530-yni0poh9	175	24	adhesion	adhesion	NN
cord-008530-yni0poh9	175	25	,	,	,
cord-008530-yni0poh9	175	26	and	and	CC
cord-008530-yni0poh9	175	27	activation	activation	NN
cord-008530-yni0poh9	175	28	of	of	IN
cord-008530-yni0poh9	175	29	circulating	circulate	VBG
cord-008530-yni0poh9	175	30	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	175	31	independently	independently	RB
cord-008530-yni0poh9	175	32	of	of	IN
cord-008530-yni0poh9	175	33	integrin	integrin	NN
cord-008530-yni0poh9	175	34	or	or	CC
cord-008530-yni0poh9	175	35	adhesion	adhesion	NN
cord-008530-yni0poh9	175	36	molecule	molecule	NN
cord-008530-yni0poh9	175	37	involvement	involvement	NN
cord-008530-yni0poh9	175	38	(	(	-LRB-
cord-008530-yni0poh9	175	39	Fong	Fong	NNP
cord-008530-yni0poh9	175	40	et	et	NNP
cord-008530-yni0poh9	175	41	al	al	NNP
cord-008530-yni0poh9	175	42	.	.	NNP
cord-008530-yni0poh9	175	43	,	,	,
cord-008530-yni0poh9	175	44	1998	1998	CD
cord-008530-yni0poh9	175	45	)	)	-RRB-
cord-008530-yni0poh9	175	46	.	.	.
cord-008530-yni0poh9	176	1	Thus	thus	RB
cord-008530-yni0poh9	176	2	,	,	,
cord-008530-yni0poh9	176	3	fractalkine	fractalkine	JJ
cord-008530-yni0poh9	176	4	not	not	RB
cord-008530-yni0poh9	176	5	only	only	RB
cord-008530-yni0poh9	176	6	induces	induce	VBZ
cord-008530-yni0poh9	176	7	the	the	DT
cord-008530-yni0poh9	176	8	migration	migration	NN
cord-008530-yni0poh9	176	9	of	of	IN
cord-008530-yni0poh9	176	10	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	176	11	but	but	CC
cord-008530-yni0poh9	176	12	also	also	RB
cord-008530-yni0poh9	176	13	facilitates	facilitate	VBZ
cord-008530-yni0poh9	176	14	their	-PRON-	PRP$
cord-008530-yni0poh9	176	15	adhesion	adhesion	NN
cord-008530-yni0poh9	176	16	directly	directly	RB
cord-008530-yni0poh9	176	17	to	to	IN
cord-008530-yni0poh9	176	18	the	the	DT
cord-008530-yni0poh9	176	19	endothelium	endothelium	NN
cord-008530-yni0poh9	176	20	at	at	IN
cord-008530-yni0poh9	176	21	sites	site	NNS
cord-008530-yni0poh9	176	22	of	of	IN
cord-008530-yni0poh9	176	23	inflammation	inflammation	NN
cord-008530-yni0poh9	176	24	.	.	.
cord-008530-yni0poh9	177	1	Fractalkine	Fractalkine	NNP
cord-008530-yni0poh9	177	2	has	have	VBZ
cord-008530-yni0poh9	177	3	been	be	VBN
cord-008530-yni0poh9	177	4	shown	show	VBN
cord-008530-yni0poh9	177	5	to	to	TO
cord-008530-yni0poh9	177	6	foster	foster	VB
cord-008530-yni0poh9	177	7	the	the	DT
cord-008530-yni0poh9	177	8	migration	migration	NN
cord-008530-yni0poh9	177	9	of	of	IN
cord-008530-yni0poh9	177	10	monocytes	monocyte	NNS
cord-008530-yni0poh9	177	11	,	,	,
cord-008530-yni0poh9	177	12	T	t	NN
cord-008530-yni0poh9	177	13	cells	cell	NNS
cord-008530-yni0poh9	177	14	,	,	,
cord-008530-yni0poh9	177	15	and	and	CC
cord-008530-yni0poh9	177	16	NK	NK	NNP
cord-008530-yni0poh9	177	17	cells	cell	NNS
cord-008530-yni0poh9	177	18	(	(	-LRB-
cord-008530-yni0poh9	178	1	Hedrick	Hedrick	NNP
cord-008530-yni0poh9	178	2	et	et	NNP
cord-008530-yni0poh9	178	3	al	al	NNP
cord-008530-yni0poh9	178	4	.	.	.
cord-008530-yni0poh9	179	1	,	,	,
cord-008530-yni0poh9	179	2	1997	1997	CD
cord-008530-yni0poh9	179	3	;	;	:
cord-008530-yni0poh9	179	4	Kelner	Kelner	NNP
cord-008530-yni0poh9	179	5	et	et	NNP
cord-008530-yni0poh9	179	6	al	al	NNP
cord-008530-yni0poh9	179	7	.	.	NNP
cord-008530-yni0poh9	179	8	,	,	,
cord-008530-yni0poh9	179	9	1994	1994	CD
cord-008530-yni0poh9	179	10	)	)	-RRB-
cord-008530-yni0poh9	179	11	.	.	.
cord-008530-yni0poh9	180	1	The	the	DT
cord-008530-yni0poh9	180	2	receptor	receptor	NN
cord-008530-yni0poh9	180	3	for	for	IN
cord-008530-yni0poh9	180	4	fractalkine	fractalkine	NN
cord-008530-yni0poh9	180	5	was	be	VBD
cord-008530-yni0poh9	180	6	originally	originally	RB
cord-008530-yni0poh9	180	7	cloned	clone	VBN
cord-008530-yni0poh9	180	8	from	from	IN
cord-008530-yni0poh9	180	9	a	a	DT
cord-008530-yni0poh9	180	10	rat	rat	NN
cord-008530-yni0poh9	180	11	brainstem	brainstem	NNP
cord-008530-yni0poh9	180	12	cDNA	cDNA	NNP
cord-008530-yni0poh9	180	13	library	library	NNP
cord-008530-yni0poh9	180	14	and	and	CC
cord-008530-yni0poh9	180	15	named	name	VBN
cord-008530-yni0poh9	180	16	RBSll	rbsll	XX
cord-008530-yni0poh9	181	1	(	(	-LRB-
cord-008530-yni0poh9	181	2	Harrison	Harrison	NNP
cord-008530-yni0poh9	181	3	et	et	NNP
cord-008530-yni0poh9	181	4	al	al	NNP
cord-008530-yni0poh9	181	5	.	.	NNP
cord-008530-yni0poh9	181	6	,	,	,
cord-008530-yni0poh9	181	7	1994	1994	CD
cord-008530-yni0poh9	181	8	)	)	-RRB-
cord-008530-yni0poh9	181	9	.	.	.
cord-008530-yni0poh9	182	1	Subsequently	subsequently	RB
cord-008530-yni0poh9	182	2	,	,	,
cord-008530-yni0poh9	182	3	the	the	DT
cord-008530-yni0poh9	182	4	human	human	JJ
cord-008530-yni0poh9	182	5	receptor	receptor	NN
cord-008530-yni0poh9	182	6	was	be	VBD
cord-008530-yni0poh9	182	7	identified	identify	VBN
cord-008530-yni0poh9	182	8	as	as	IN
cord-008530-yni0poh9	182	9	V28	V28	NNP
cord-008530-yni0poh9	182	10	(	(	-LRB-
cord-008530-yni0poh9	182	11	Raport	Raport	NNP
cord-008530-yni0poh9	182	12	et	et	FW
cord-008530-yni0poh9	182	13	al	al	NNP
cord-008530-yni0poh9	182	14	.	.	NNP
cord-008530-yni0poh9	182	15	,	,	,
cord-008530-yni0poh9	182	16	1995	1995	CD
cord-008530-yni0poh9	182	17	)	)	-RRB-
cord-008530-yni0poh9	182	18	,	,	,
cord-008530-yni0poh9	182	19	or	or	CC
cord-008530-yni0poh9	182	20	CMKBLR1	CMKBLR1	NNP
cord-008530-yni0poh9	182	21	,	,	,
cord-008530-yni0poh9	182	22	which	which	WDT
cord-008530-yni0poh9	182	23	is	be	VBZ
cord-008530-yni0poh9	182	24	highly	highly	RB
cord-008530-yni0poh9	182	25	expressed	express	VBN
cord-008530-yni0poh9	182	26	in	in	IN
cord-008530-yni0poh9	182	27	the	the	DT
cord-008530-yni0poh9	182	28	brain	brain	NN
cord-008530-yni0poh9	182	29	and	and	CC
cord-008530-yni0poh9	182	30	in	in	IN
cord-008530-yni0poh9	182	31	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	182	32	,	,	,
cord-008530-yni0poh9	182	33	monocytes	monocyte	NNS
cord-008530-yni0poh9	182	34	/	/	SYM
cord-008530-yni0poh9	182	35	macrophages	macrophage	NNS
cord-008530-yni0poh9	182	36	,	,	,
cord-008530-yni0poh9	182	37	and	and	CC
cord-008530-yni0poh9	182	38	T	t	NN
cord-008530-yni0poh9	182	39	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	182	40	(	(	-LRB-
cord-008530-yni0poh9	182	41	Combadiere	Combadiere	NNP
cord-008530-yni0poh9	182	42	et	et	FW
cord-008530-yni0poh9	182	43	al	al	NNP
cord-008530-yni0poh9	182	44	.	.	NNP
cord-008530-yni0poh9	182	45	,	,	,
cord-008530-yni0poh9	182	46	1995	1995	CD
cord-008530-yni0poh9	182	47	)	)	-RRB-
cord-008530-yni0poh9	182	48	.	.	.
cord-008530-yni0poh9	183	1	Imai	Imai	NNP
cord-008530-yni0poh9	183	2	et	et	NNP
cord-008530-yni0poh9	183	3	al	al	NNP
cord-008530-yni0poh9	183	4	.	.	.
cord-008530-yni0poh9	184	1	(	(	-LRB-
cord-008530-yni0poh9	184	2	1997	1997	CD
cord-008530-yni0poh9	184	3	)	)	-RRB-
cord-008530-yni0poh9	184	4	identified	identify	VBD
cord-008530-yni0poh9	184	5	this	this	DT
cord-008530-yni0poh9	184	6	molecule	molecule	NN
cord-008530-yni0poh9	184	7	as	as	IN
cord-008530-yni0poh9	184	8	being	be	VBG
cord-008530-yni0poh9	184	9	the	the	DT
cord-008530-yni0poh9	184	10	fractalkine	fractalkine	JJ
cord-008530-yni0poh9	184	11	receptor	receptor	NN
cord-008530-yni0poh9	184	12	(	(	-LRB-
cord-008530-yni0poh9	184	13	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	184	14	)	)	-RRB-
cord-008530-yni0poh9	184	15	that	that	WDT
cord-008530-yni0poh9	184	16	is	be	VBZ
cord-008530-yni0poh9	184	17	expressed	express	VBN
cord-008530-yni0poh9	184	18	mainly	mainly	RB
cord-008530-yni0poh9	184	19	by	by	IN
cord-008530-yni0poh9	184	20	NK	NK	NNP
cord-008530-yni0poh9	184	21	cells	cell	NNS
cord-008530-yni0poh9	184	22	and	and	CC
cord-008530-yni0poh9	184	23	monocytes	monocyte	NNS
cord-008530-yni0poh9	184	24	and	and	CC
cord-008530-yni0poh9	184	25	to	to	IN
cord-008530-yni0poh9	184	26	a	a	DT
cord-008530-yni0poh9	184	27	lesser	less	JJR
cord-008530-yni0poh9	184	28	extent	extent	NN
cord-008530-yni0poh9	184	29	in	in	IN
cord-008530-yni0poh9	184	30	CD8	CD8	NNP
cord-008530-yni0poh9	184	31	÷	÷	NNP
cord-008530-yni0poh9	184	32	T	T	NNP
cord-008530-yni0poh9	184	33	cells	cell	NNS
cord-008530-yni0poh9	184	34	.	.	.
cord-008530-yni0poh9	185	1	Many	many	JJ
cord-008530-yni0poh9	185	2	of	of	IN
cord-008530-yni0poh9	185	3	the	the	DT
cord-008530-yni0poh9	185	4	large	large	JJ
cord-008530-yni0poh9	185	5	DNA	dna	NN
cord-008530-yni0poh9	185	6	viruses	virus	NNS
cord-008530-yni0poh9	185	7	are	be	VBP
cord-008530-yni0poh9	185	8	infamous	infamous	JJ
cord-008530-yni0poh9	185	9	for	for	IN
cord-008530-yni0poh9	185	10	their	-PRON-	PRP$
cord-008530-yni0poh9	185	11	ability	ability	NN
cord-008530-yni0poh9	185	12	to	to	TO
cord-008530-yni0poh9	185	13	undermine	undermine	VB
cord-008530-yni0poh9	185	14	host	host	NN
cord-008530-yni0poh9	185	15	immunity	immunity	NN
cord-008530-yni0poh9	185	16	.	.	.
cord-008530-yni0poh9	186	1	Two	two	CD
cord-008530-yni0poh9	186	2	genres	genre	NNS
cord-008530-yni0poh9	186	3	of	of	IN
cord-008530-yni0poh9	186	4	viruses	virus	NNS
cord-008530-yni0poh9	186	5	,	,	,
cord-008530-yni0poh9	186	6	the	the	DT
cord-008530-yni0poh9	186	7	herpesviruses	herpesviruse	NNS
cord-008530-yni0poh9	186	8	and	and	CC
cord-008530-yni0poh9	186	9	poxviruses	poxvirus	NNS
cord-008530-yni0poh9	186	10	,	,	,
cord-008530-yni0poh9	186	11	were	be	VBD
cord-008530-yni0poh9	186	12	recently	recently	RB
cord-008530-yni0poh9	186	13	shown	show	VBN
cord-008530-yni0poh9	186	14	to	to	TO
cord-008530-yni0poh9	186	15	contain	contain	VB
cord-008530-yni0poh9	186	16	open	open	JJ
cord-008530-yni0poh9	186	17	reading	reading	NN
cord-008530-yni0poh9	186	18	frames	frame	NNS
cord-008530-yni0poh9	186	19	(	(	-LRB-
cord-008530-yni0poh9	186	20	ORFs	ORFs	NNP
cord-008530-yni0poh9	186	21	)	)	-RRB-
cord-008530-yni0poh9	186	22	that	that	WDT
cord-008530-yni0poh9	186	23	encode	encode	VBP
cord-008530-yni0poh9	186	24	homologs	homolog	NNS
cord-008530-yni0poh9	186	25	of	of	IN
cord-008530-yni0poh9	186	26	mammalian	mammalian	JJ
cord-008530-yni0poh9	186	27	chemokines	chemokine	NNS
cord-008530-yni0poh9	186	28	and	and	CC
cord-008530-yni0poh9	186	29	chemokine	chemokine	NN
cord-008530-yni0poh9	186	30	receptors	receptor	NNS
cord-008530-yni0poh9	186	31	(	(	-LRB-
cord-008530-yni0poh9	186	32	for	for	IN
cord-008530-yni0poh9	186	33	detailed	detailed	JJ
cord-008530-yni0poh9	186	34	reviews	review	NNS
cord-008530-yni0poh9	186	35	,	,	,
cord-008530-yni0poh9	186	36	see	see	VB
cord-008530-yni0poh9	186	37	Ahuja	Ahuja	NNP
cord-008530-yni0poh9	186	38	et	et	NNP
cord-008530-yni0poh9	186	39	al	al	NNP
cord-008530-yni0poh9	186	40	.	.	.
cord-008530-yni0poh9	187	1	,	,	,
cord-008530-yni0poh9	187	2	1994	1994	CD
cord-008530-yni0poh9	187	3	;	;	:
cord-008530-yni0poh9	187	4	Dairaghi	Dairaghi	NNP
cord-008530-yni0poh9	187	5	et	et	FW
cord-008530-yni0poh9	187	6	al	al	NNP
cord-008530-yni0poh9	187	7	.	.	NNP
cord-008530-yni0poh9	187	8	,	,	,
cord-008530-yni0poh9	187	9	1998	1998	CD
cord-008530-yni0poh9	187	10	;	;	:
cord-008530-yni0poh9	187	11	Lalani	Lalani	NNP
cord-008530-yni0poh9	187	12	et	et	NNP
cord-008530-yni0poh9	187	13	al	al	NNP
cord-008530-yni0poh9	187	14	.	.	NNP
cord-008530-yni0poh9	187	15	,	,	,
cord-008530-yni0poh9	187	16	2000	2000	CD
cord-008530-yni0poh9	187	17	;	;	:
cord-008530-yni0poh9	187	18	Murphy	Murphy	NNP
cord-008530-yni0poh9	187	19	,	,	,
cord-008530-yni0poh9	187	20	1994	1994	CD
cord-008530-yni0poh9	187	21	;	;	:
cord-008530-yni0poh9	187	22	Smith	Smith	NNP
cord-008530-yni0poh9	187	23	et	et	NNP
cord-008530-yni0poh9	187	24	al	al	NNP
cord-008530-yni0poh9	187	25	.	.	NNP
cord-008530-yni0poh9	187	26	,	,	,
cord-008530-yni0poh9	187	27	1997	1997	CD
cord-008530-yni0poh9	187	28	)	)	-RRB-
cord-008530-yni0poh9	187	29	.	.	.
cord-008530-yni0poh9	188	1	Kaposi	Kaposi	NNP
cord-008530-yni0poh9	188	2	's	's	POS
cord-008530-yni0poh9	188	3	sarcoma	sarcoma	NN
cord-008530-yni0poh9	188	4	-	-	HYPH
cord-008530-yni0poh9	188	5	associated	associate	VBN
cord-008530-yni0poh9	188	6	herpes	herpes	NN
cord-008530-yni0poh9	188	7	virus	virus	NN
cord-008530-yni0poh9	188	8	(	(	-LRB-
cord-008530-yni0poh9	188	9	KSHV	KSHV	NNP
cord-008530-yni0poh9	188	10	)	)	-RRB-
cord-008530-yni0poh9	188	11	encodes	encode	VBZ
cord-008530-yni0poh9	188	12	three	three	CD
cord-008530-yni0poh9	188	13	CC	CC	NNP
cord-008530-yni0poh9	188	14	-	-	HYPH
cord-008530-yni0poh9	188	15	like	like	JJ
cord-008530-yni0poh9	188	16	chemokines	chemokine	NNS
cord-008530-yni0poh9	188	17	,	,	,
cord-008530-yni0poh9	188	18	vMIP	vmip	NN
cord-008530-yni0poh9	188	19	-	-	:
cord-008530-yni0poh9	188	20	I	I	NNP
cord-008530-yni0poh9	188	21	,	,	,
cord-008530-yni0poh9	188	22	vMIP	vMIP	NNP
cord-008530-yni0poh9	188	23	-	-	HYPH
cord-008530-yni0poh9	188	24	II	II	NNP
cord-008530-yni0poh9	188	25	,	,	,
cord-008530-yni0poh9	188	26	and	and	CC
cord-008530-yni0poh9	188	27	vMIP	vmip	NN
cord-008530-yni0poh9	188	28	-	-	HYPH
cord-008530-yni0poh9	188	29	III	III	NNP
cord-008530-yni0poh9	188	30	.	.	.
cord-008530-yni0poh9	189	1	The	the	DT
cord-008530-yni0poh9	189	2	vMIP	vmip	NN
cord-008530-yni0poh9	189	3	-	-	:
cord-008530-yni0poh9	189	4	I	i	NN
cord-008530-yni0poh9	189	5	and	and	CC
cord-008530-yni0poh9	189	6	vMIP	vMIP	NNP
cord-008530-yni0poh9	189	7	-	-	HYPH
cord-008530-yni0poh9	189	8	II	II	NNP
cord-008530-yni0poh9	189	9	show	show	VBP
cord-008530-yni0poh9	189	10	60	60	CD
cord-008530-yni0poh9	189	11	%	%	NN
cord-008530-yni0poh9	189	12	sequence	sequence	NN
cord-008530-yni0poh9	189	13	identity	identity	NN
cord-008530-yni0poh9	189	14	to	to	IN
cord-008530-yni0poh9	189	15	each	each	DT
cord-008530-yni0poh9	189	16	other	other	JJ
cord-008530-yni0poh9	189	17	and	and	CC
cord-008530-yni0poh9	189	18	43	43	CD
cord-008530-yni0poh9	189	19	%	%	NN
cord-008530-yni0poh9	189	20	and	and	CC
cord-008530-yni0poh9	189	21	52	52	CD
cord-008530-yni0poh9	189	22	%	%	NN
cord-008530-yni0poh9	189	23	identity	identity	NN
cord-008530-yni0poh9	189	24	to	to	IN
cord-008530-yni0poh9	189	25	MIP	MIP	NNP
cord-008530-yni0poh9	189	26	-	-	HYPH
cord-008530-yni0poh9	189	27	la	la	NNP
cord-008530-yni0poh9	189	28	,	,	,
cord-008530-yni0poh9	189	29	while	while	IN
cord-008530-yni0poh9	189	30	vMIP	vMIP	NNS
cord-008530-yni0poh9	189	31	-	-	HYPH
cord-008530-yni0poh9	189	32	III	III	NNP
cord-008530-yni0poh9	189	33	is	be	VBZ
cord-008530-yni0poh9	189	34	more	more	RBR
cord-008530-yni0poh9	189	35	distantly	distantly	RB
cord-008530-yni0poh9	189	36	related	related	JJ
cord-008530-yni0poh9	189	37	to	to	IN
cord-008530-yni0poh9	189	38	its	-PRON-	PRP$
cord-008530-yni0poh9	189	39	viral	viral	JJ
cord-008530-yni0poh9	189	40	and	and	CC
cord-008530-yni0poh9	189	41	mammalian	mammalian	JJ
cord-008530-yni0poh9	189	42	counterparts	counterpart	NNS
cord-008530-yni0poh9	189	43	(	(	-LRB-
cord-008530-yni0poh9	189	44	Stine	Stine	NNP
cord-008530-yni0poh9	189	45	et	et	NNP
cord-008530-yni0poh9	189	46	al	al	NNP
cord-008530-yni0poh9	189	47	.	.	NNP
cord-008530-yni0poh9	189	48	,	,	,
cord-008530-yni0poh9	189	49	1999	1999	CD
cord-008530-yni0poh9	189	50	)	)	-RRB-
cord-008530-yni0poh9	189	51	.	.	.
cord-008530-yni0poh9	190	1	Of	of	IN
cord-008530-yni0poh9	190	2	the	the	DT
cord-008530-yni0poh9	190	3	three	three	CD
cord-008530-yni0poh9	190	4	viral	viral	JJ
cord-008530-yni0poh9	190	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	190	6	,	,	,
cord-008530-yni0poh9	190	7	the	the	DT
cord-008530-yni0poh9	190	8	function	function	NN
cord-008530-yni0poh9	190	9	of	of	IN
cord-008530-yni0poh9	190	10	vMIP	vMIP	NNP
cord-008530-yni0poh9	190	11	-	-	HYPH
cord-008530-yni0poh9	190	12	II	II	NNP
cord-008530-yni0poh9	190	13	is	be	VBZ
cord-008530-yni0poh9	190	14	the	the	DT
cord-008530-yni0poh9	190	15	best	well	RBS
cord-008530-yni0poh9	190	16	characterized	characterize	VBN
cord-008530-yni0poh9	190	17	.	.	.
cord-008530-yni0poh9	191	1	Receptor	receptor	NN
cord-008530-yni0poh9	191	2	binding	binding	NN
cord-008530-yni0poh9	191	3	studies	study	NNS
cord-008530-yni0poh9	191	4	suggest	suggest	VBP
cord-008530-yni0poh9	191	5	vMIP	vMIP	NNS
cord-008530-yni0poh9	191	6	-	-	HYPH
cord-008530-yni0poh9	191	7	II	II	NNP
cord-008530-yni0poh9	191	8	is	be	VBZ
cord-008530-yni0poh9	191	9	a	a	DT
cord-008530-yni0poh9	191	10	ligand	ligand	NN
cord-008530-yni0poh9	191	11	for	for	IN
cord-008530-yni0poh9	191	12	CCR3	CCR3	NNP
cord-008530-yni0poh9	191	13	(	(	-LRB-
cord-008530-yni0poh9	191	14	Boshoff	Boshoff	NNP
cord-008530-yni0poh9	191	15	et	et	NNP
cord-008530-yni0poh9	191	16	al	al	NNP
cord-008530-yni0poh9	191	17	.	.	NNP
cord-008530-yni0poh9	191	18	,	,	,
cord-008530-yni0poh9	191	19	1997	1997	CD
cord-008530-yni0poh9	191	20	)	)	-RRB-
cord-008530-yni0poh9	191	21	.	.	.
cord-008530-yni0poh9	192	1	In	in	IN
cord-008530-yni0poh9	192	2	addition	addition	NN
cord-008530-yni0poh9	192	3	to	to	IN
cord-008530-yni0poh9	192	4	being	be	VBG
cord-008530-yni0poh9	192	5	a	a	DT
cord-008530-yni0poh9	192	6	potent	potent	JJ
cord-008530-yni0poh9	192	7	inhibitor	inhibitor	NN
cord-008530-yni0poh9	192	8	of	of	IN
cord-008530-yni0poh9	192	9	HIV	HIV	NNP
cord-008530-yni0poh9	192	10	infection	infection	NN
cord-008530-yni0poh9	192	11	mediated	mediate	VBN
cord-008530-yni0poh9	192	12	principally	principally	RB
cord-008530-yni0poh9	192	13	through	through	IN
cord-008530-yni0poh9	192	14	this	this	DT
cord-008530-yni0poh9	192	15	receptor	receptor	NN
cord-008530-yni0poh9	192	16	(	(	-LRB-
cord-008530-yni0poh9	192	17	Boshoffet	Boshoffet	NNP
cord-008530-yni0poh9	192	18	al	al	NNP
cord-008530-yni0poh9	192	19	.	.	NNP
cord-008530-yni0poh9	192	20	,	,	,
cord-008530-yni0poh9	192	21	1997	1997	CD
cord-008530-yni0poh9	192	22	)	)	-RRB-
cord-008530-yni0poh9	192	23	,	,	,
cord-008530-yni0poh9	192	24	vMIP	vMIP	NNP
cord-008530-yni0poh9	192	25	-	-	HYPH
cord-008530-yni0poh9	192	26	II	II	NNP
cord-008530-yni0poh9	192	27	is	be	VBZ
cord-008530-yni0poh9	192	28	able	able	JJ
cord-008530-yni0poh9	192	29	to	to	TO
cord-008530-yni0poh9	192	30	mobilize	mobilize	VB
cord-008530-yni0poh9	192	31	calcium	calcium	NN
cord-008530-yni0poh9	192	32	and	and	CC
cord-008530-yni0poh9	192	33	stimulate	stimulate	VB
cord-008530-yni0poh9	192	34	the	the	DT
cord-008530-yni0poh9	192	35	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	192	36	of	of	IN
cord-008530-yni0poh9	192	37	eosinophils	eosinophil	NNS
cord-008530-yni0poh9	192	38	where	where	WRB
cord-008530-yni0poh9	192	39	CCR3	CCR3	NNP
cord-008530-yni0poh9	192	40	is	be	VBZ
cord-008530-yni0poh9	192	41	predominantly	predominantly	RB
cord-008530-yni0poh9	192	42	expressed	express	VBN
cord-008530-yni0poh9	192	43	(	(	-LRB-
cord-008530-yni0poh9	192	44	Boshoffet	Boshoffet	NNP
cord-008530-yni0poh9	192	45	al	al	NNP
cord-008530-yni0poh9	192	46	.	.	NNP
cord-008530-yni0poh9	192	47	,	,	,
cord-008530-yni0poh9	192	48	1997	1997	CD
cord-008530-yni0poh9	192	49	)	)	-RRB-
cord-008530-yni0poh9	192	50	.	.	.
cord-008530-yni0poh9	193	1	In	in	IN
cord-008530-yni0poh9	193	2	contrast	contrast	NN
cord-008530-yni0poh9	193	3	to	to	IN
cord-008530-yni0poh9	193	4	this	this	DT
cord-008530-yni0poh9	193	5	agonist	agonist	NN
cord-008530-yni0poh9	193	6	action	action	NN
cord-008530-yni0poh9	193	7	on	on	IN
cord-008530-yni0poh9	193	8	CCR3	CCR3	NNP
cord-008530-yni0poh9	193	9	,	,	,
cord-008530-yni0poh9	194	1	vMIP	vMIP	NNP
cord-008530-yni0poh9	194	2	-	-	HYPH
cord-008530-yni0poh9	194	3	II	II	NNP
cord-008530-yni0poh9	194	4	also	also	RB
cord-008530-yni0poh9	194	5	binds	bind	VBZ
cord-008530-yni0poh9	194	6	with	with	IN
cord-008530-yni0poh9	194	7	a	a	DT
cord-008530-yni0poh9	194	8	high	high	JJ
cord-008530-yni0poh9	194	9	degree	degree	NN
cord-008530-yni0poh9	194	10	of	of	IN
cord-008530-yni0poh9	194	11	affinity	affinity	NN
cord-008530-yni0poh9	194	12	to	to	IN
cord-008530-yni0poh9	194	13	a	a	DT
cord-008530-yni0poh9	194	14	number	number	NN
cord-008530-yni0poh9	194	15	of	of	IN
cord-008530-yni0poh9	194	16	other	other	JJ
cord-008530-yni0poh9	194	17	CC	cc	NN
cord-008530-yni0poh9	194	18	(	(	-LRB-
cord-008530-yni0poh9	194	19	CCR1	CCR1	NNP
cord-008530-yni0poh9	194	20	,	,	,
cord-008530-yni0poh9	194	21	2	2	CD
cord-008530-yni0poh9	194	22	,	,	,
cord-008530-yni0poh9	194	23	5	5	CD
cord-008530-yni0poh9	194	24	)	)	-RRB-
cord-008530-yni0poh9	194	25	and	and	CC
cord-008530-yni0poh9	194	26	CXC	CXC	NNP
cord-008530-yni0poh9	194	27	chemokine	chemokine	NN
cord-008530-yni0poh9	194	28	receptors	receptor	NNS
cord-008530-yni0poh9	194	29	(	(	-LRB-
cord-008530-yni0poh9	194	30	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	194	31	)	)	-RRB-
cord-008530-yni0poh9	194	32	,	,	,
cord-008530-yni0poh9	194	33	where	where	WRB
cord-008530-yni0poh9	194	34	it	-PRON-	PRP
cord-008530-yni0poh9	194	35	acts	act	VBZ
cord-008530-yni0poh9	194	36	as	as	IN
cord-008530-yni0poh9	194	37	an	an	DT
cord-008530-yni0poh9	194	38	antagonist	antagonist	NN
cord-008530-yni0poh9	194	39	(	(	-LRB-
cord-008530-yni0poh9	194	40	Kledal	Kledal	NNP
cord-008530-yni0poh9	194	41	et	et	FW
cord-008530-yni0poh9	194	42	al	al	NNP
cord-008530-yni0poh9	194	43	.	.	NNP
cord-008530-yni0poh9	194	44	,	,	,
cord-008530-yni0poh9	194	45	1997	1997	CD
cord-008530-yni0poh9	194	46	)	)	-RRB-
cord-008530-yni0poh9	194	47	,	,	,
cord-008530-yni0poh9	194	48	as	as	RB
cord-008530-yni0poh9	194	49	well	well	RB
cord-008530-yni0poh9	194	50	as	as	IN
cord-008530-yni0poh9	194	51	to	to	IN
cord-008530-yni0poh9	194	52	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	194	53	.	.	.
cord-008530-yni0poh9	195	1	Human	human	JJ
cord-008530-yni0poh9	195	2	monocyte	monocyte	JJ
cord-008530-yni0poh9	195	3	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	195	4	induced	induce	VBN
cord-008530-yni0poh9	195	5	by	by	IN
cord-008530-yni0poh9	195	6	RANTES	RANTES	NNP
cord-008530-yni0poh9	195	7	,	,	,
cord-008530-yni0poh9	195	8	MIP	MIP	NNP
cord-008530-yni0poh9	195	9	-	-	HYPH
cord-008530-yni0poh9	195	10	I(~	I(~	NNP
cord-008530-yni0poh9	195	11	,	,	,
cord-008530-yni0poh9	195	12	and	and	CC
cord-008530-yni0poh9	195	13	MIP	MIP	NNP
cord-008530-yni0poh9	195	14	-	-	HYPH
cord-008530-yni0poh9	195	15	I[~	I[~	NNP
cord-008530-yni0poh9	195	16	is	be	VBZ
cord-008530-yni0poh9	195	17	inhibited	inhibit	VBN
cord-008530-yni0poh9	195	18	by	by	IN
cord-008530-yni0poh9	195	19	vMIP	vmip	NN
cord-008530-yni0poh9	195	20	-	-	HYPH
cord-008530-yni0poh9	195	21	II	II	NNP
cord-008530-yni0poh9	195	22	,	,	,
cord-008530-yni0poh9	195	23	suggesting	suggest	VBG
cord-008530-yni0poh9	195	24	that	that	IN
cord-008530-yni0poh9	195	25	this	this	DT
cord-008530-yni0poh9	195	26	viral	viral	JJ
cord-008530-yni0poh9	195	27	mediator	mediator	NN
cord-008530-yni0poh9	195	28	may	may	MD
cord-008530-yni0poh9	195	29	be	be	VB
cord-008530-yni0poh9	195	30	a	a	DT
cord-008530-yni0poh9	195	31	broad	broad	JJ
cord-008530-yni0poh9	195	32	-	-	HYPH
cord-008530-yni0poh9	195	33	spectrum	spectrum	NN
cord-008530-yni0poh9	195	34	chemokine	chemokine	NN
cord-008530-yni0poh9	195	35	antagonist	antagonist	NN
cord-008530-yni0poh9	195	36	.	.	.
cord-008530-yni0poh9	196	1	Recently	recently	RB
cord-008530-yni0poh9	196	2	,	,	,
cord-008530-yni0poh9	196	3	vMIP	vmip	RB
cord-008530-yni0poh9	196	4	-	-	:
cord-008530-yni0poh9	196	5	I	-PRON-	PRP
cord-008530-yni0poh9	196	6	was	be	VBD
cord-008530-yni0poh9	196	7	shown	show	VBN
cord-008530-yni0poh9	196	8	to	to	TO
cord-008530-yni0poh9	196	9	selectively	selectively	RB
cord-008530-yni0poh9	196	10	bind	bind	VB
cord-008530-yni0poh9	196	11	to	to	IN
cord-008530-yni0poh9	196	12	CCR8	CCR8	NNP
cord-008530-yni0poh9	196	13	(	(	-LRB-
cord-008530-yni0poh9	196	14	a	a	DT
cord-008530-yni0poh9	196	15	CC	cc	NN
cord-008530-yni0poh9	196	16	chemokine	chemokine	NN
cord-008530-yni0poh9	196	17	receptor	receptor	NN
cord-008530-yni0poh9	196	18	associated	associate	VBN
cord-008530-yni0poh9	196	19	with	with	IN
cord-008530-yni0poh9	196	20	Th2	Th2	NNP
cord-008530-yni0poh9	196	21	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	196	22	)	)	-RRB-
cord-008530-yni0poh9	196	23	,	,	,
cord-008530-yni0poh9	196	24	acting	act	VBG
cord-008530-yni0poh9	196	25	as	as	IN
cord-008530-yni0poh9	196	26	an	an	DT
cord-008530-yni0poh9	196	27	agonist	agonist	NN
cord-008530-yni0poh9	196	28	and	and	CC
cord-008530-yni0poh9	196	29	stimulating	stimulate	VBG
cord-008530-yni0poh9	196	30	Ca	Ca	NNP
cord-008530-yni0poh9	196	31	2	2	CD
cord-008530-yni0poh9	196	32	+	+	CC
cord-008530-yni0poh9	196	33	mobilization	mobilization	NN
cord-008530-yni0poh9	196	34	on	on	IN
cord-008530-yni0poh9	196	35	human	human	JJ
cord-008530-yni0poh9	196	36	T	T	NNP
cord-008530-yni0poh9	196	37	cells	cell	NNS
cord-008530-yni0poh9	196	38	.	.	.
cord-008530-yni0poh9	197	1	Interestingly	interestingly	RB
cord-008530-yni0poh9	197	2	,	,	,
cord-008530-yni0poh9	197	3	vMIP	vMIP	NNP
cord-008530-yni0poh9	197	4	-	-	HYPH
cord-008530-yni0poh9	197	5	II	II	NNP
cord-008530-yni0poh9	197	6	also	also	RB
cord-008530-yni0poh9	197	7	binds	bind	VBZ
cord-008530-yni0poh9	197	8	to	to	IN
cord-008530-yni0poh9	197	9	CCR8	CCR8	NNP
cord-008530-yni0poh9	197	10	;	;	:
cord-008530-yni0poh9	197	11	however	however	RB
cord-008530-yni0poh9	197	12	,	,	,
cord-008530-yni0poh9	197	13	this	this	DT
cord-008530-yni0poh9	197	14	is	be	VBZ
cord-008530-yni0poh9	197	15	associated	associate	VBN
cord-008530-yni0poh9	197	16	with	with	IN
cord-008530-yni0poh9	197	17	antagonistic	antagonistic	JJ
cord-008530-yni0poh9	197	18	actions	action	NNS
cord-008530-yni0poh9	197	19	.	.	.
cord-008530-yni0poh9	198	1	Kaposi	Kaposi	NNP
cord-008530-yni0poh9	198	2	's	's	POS
cord-008530-yni0poh9	198	3	sarcoma	sarcoma	NN
cord-008530-yni0poh9	198	4	is	be	VBZ
cord-008530-yni0poh9	198	5	an	an	DT
cord-008530-yni0poh9	198	6	angioproliferative	angioproliferative	JJ
cord-008530-yni0poh9	198	7	disorder	disorder	NN
cord-008530-yni0poh9	198	8	,	,	,
cord-008530-yni0poh9	198	9	so	so	CC
cord-008530-yni0poh9	198	10	it	-PRON-	PRP
cord-008530-yni0poh9	198	11	is	be	VBZ
cord-008530-yni0poh9	198	12	interesting	interesting	JJ
cord-008530-yni0poh9	198	13	that	that	IN
cord-008530-yni0poh9	198	14	in	in	IN
cord-008530-yni0poh9	198	15	addition	addition	NN
cord-008530-yni0poh9	198	16	to	to	IN
cord-008530-yni0poh9	198	17	deviation	deviation	NN
cord-008530-yni0poh9	198	18	of	of	IN
cord-008530-yni0poh9	198	19	the	the	DT
cord-008530-yni0poh9	198	20	host	host	NN
cord-008530-yni0poh9	198	21	chemokine	chemokine	NN
cord-008530-yni0poh9	198	22	response	response	NN
cord-008530-yni0poh9	198	23	,	,	,
cord-008530-yni0poh9	199	1	vMIP	vmip	LS
cord-008530-yni0poh9	199	2	-	-	:
cord-008530-yni0poh9	199	3	I	I	NNP
cord-008530-yni0poh9	199	4	and	and	CC
cord-008530-yni0poh9	199	5	vMIP	vMIP	NNP
cord-008530-yni0poh9	199	6	-	-	HYPH
cord-008530-yni0poh9	199	7	II	ii	NN
cord-008530-yni0poh9	199	8	both	both	DT
cord-008530-yni0poh9	199	9	induce	induce	VBP
cord-008530-yni0poh9	199	10	angiogenesis	angiogenesis	NN
cord-008530-yni0poh9	199	11	in	in	IN
cord-008530-yni0poh9	199	12	a	a	DT
cord-008530-yni0poh9	199	13	chick	chick	NN
cord-008530-yni0poh9	199	14	chorioallantoic	chorioallantoic	NNP
cord-008530-yni0poh9	199	15	assay	assay	NNP
cord-008530-yni0poh9	199	16	(	(	-LRB-
cord-008530-yni0poh9	199	17	Boshoff	Boshoff	NNP
cord-008530-yni0poh9	199	18	et	et	NNP
cord-008530-yni0poh9	199	19	al	al	NNP
cord-008530-yni0poh9	199	20	.	.	NNP
cord-008530-yni0poh9	199	21	,	,	,
cord-008530-yni0poh9	199	22	1997	1997	CD
cord-008530-yni0poh9	199	23	)	)	-RRB-
cord-008530-yni0poh9	199	24	.	.	.
cord-008530-yni0poh9	200	1	Thus	thus	RB
cord-008530-yni0poh9	200	2	these	these	DT
cord-008530-yni0poh9	200	3	viral	viral	JJ
cord-008530-yni0poh9	200	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	200	5	might	may	MD
cord-008530-yni0poh9	200	6	contribute	contribute	VB
cord-008530-yni0poh9	200	7	directly	directly	RB
cord-008530-yni0poh9	200	8	to	to	IN
cord-008530-yni0poh9	200	9	the	the	DT
cord-008530-yni0poh9	200	10	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	200	11	of	of	IN
cord-008530-yni0poh9	200	12	the	the	DT
cord-008530-yni0poh9	200	13	proliferative	proliferative	JJ
cord-008530-yni0poh9	200	14	angiopathy	angiopathy	NN
cord-008530-yni0poh9	200	15	in	in	IN
cord-008530-yni0poh9	200	16	Kaposi	Kaposi	NNP
cord-008530-yni0poh9	200	17	's	's	POS
cord-008530-yni0poh9	200	18	sarcoma	sarcoma	NN
cord-008530-yni0poh9	200	19	.	.	.
cord-008530-yni0poh9	201	1	In	in	IN
cord-008530-yni0poh9	201	2	addition	addition	NN
cord-008530-yni0poh9	201	3	to	to	IN
cord-008530-yni0poh9	201	4	these	these	DT
cord-008530-yni0poh9	201	5	chemokine	chemokine	NN
cord-008530-yni0poh9	201	6	homologs	homolog	NNS
cord-008530-yni0poh9	201	7	,	,	,
cord-008530-yni0poh9	201	8	herpesviruses	herpesviruses	NNP
cord-008530-yni0poh9	201	9	also	also	RB
cord-008530-yni0poh9	201	10	contain	contain	VBP
cord-008530-yni0poh9	201	11	open	open	JJ
cord-008530-yni0poh9	201	12	reading	reading	NN
cord-008530-yni0poh9	201	13	frames	frame	NNS
cord-008530-yni0poh9	201	14	(	(	-LRB-
cord-008530-yni0poh9	201	15	ORFs	ORFs	NNP
cord-008530-yni0poh9	201	16	)	)	-RRB-
cord-008530-yni0poh9	201	17	that	that	WDT
cord-008530-yni0poh9	201	18	share	share	VBP
cord-008530-yni0poh9	201	19	significant	significant	JJ
cord-008530-yni0poh9	201	20	sequence	sequence	NN
cord-008530-yni0poh9	201	21	conservation	conservation	NN
cord-008530-yni0poh9	201	22	with	with	IN
cord-008530-yni0poh9	201	23	the	the	DT
cord-008530-yni0poh9	201	24	chemokine	chemokine	NN
cord-008530-yni0poh9	201	25	receptors	receptor	NNS
cord-008530-yni0poh9	201	26	.	.	.
cord-008530-yni0poh9	202	1	KSHV	KSHV	NNP
cord-008530-yni0poh9	202	2	and	and	CC
cord-008530-yni0poh9	202	3	Herpesvirus	Herpesvirus	NNP
cord-008530-yni0poh9	202	4	saimiri	saimiri	NNP
cord-008530-yni0poh9	202	5	(	(	-LRB-
cord-008530-yni0poh9	202	6	HVS	HVS	NNP
cord-008530-yni0poh9	202	7	)	)	-RRB-
cord-008530-yni0poh9	202	8	contain	contain	VBP
cord-008530-yni0poh9	202	9	ORF	ORF	NNP
cord-008530-yni0poh9	202	10	74	74	CD
cord-008530-yni0poh9	202	11	in	in	IN
cord-008530-yni0poh9	202	12	HSV	HSV	NNP
cord-008530-yni0poh9	202	13	,	,	,
cord-008530-yni0poh9	202	14	whose	whose	WP$
cord-008530-yni0poh9	202	15	sequence	sequence	NN
cord-008530-yni0poh9	202	16	is	be	VBZ
cord-008530-yni0poh9	202	17	most	most	RBS
cord-008530-yni0poh9	202	18	similar	similar	JJ
cord-008530-yni0poh9	202	19	to	to	IN
cord-008530-yni0poh9	202	20	the	the	DT
cord-008530-yni0poh9	202	21	human	human	JJ
cord-008530-yni0poh9	202	22	IL-8	il-8	NN
cord-008530-yni0poh9	202	23	receptors	receptor	NNS
cord-008530-yni0poh9	202	24	CXCR1	cxcr1	NN
cord-008530-yni0poh9	203	1	and	and	CC
cord-008530-yni0poh9	203	2	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	204	1	(	(	-LRB-
cord-008530-yni0poh9	204	2	Ahuja	Ahuja	NNP
cord-008530-yni0poh9	204	3	and	and	CC
cord-008530-yni0poh9	204	4	Murphy	Murphy	NNP
cord-008530-yni0poh9	204	5	,	,	,
cord-008530-yni0poh9	204	6	1993	1993	CD
cord-008530-yni0poh9	204	7	)	)	-RRB-
cord-008530-yni0poh9	204	8	.	.	.
cord-008530-yni0poh9	205	1	Like	like	IN
cord-008530-yni0poh9	205	2	CXCR1	CXCR1	NNS
cord-008530-yni0poh9	205	3	and	and	CC
cord-008530-yni0poh9	205	4	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	205	5	,	,	,
cord-008530-yni0poh9	205	6	ORF	ORF	NNP
cord-008530-yni0poh9	205	7	74	74	CD
cord-008530-yni0poh9	205	8	binds	bind	VBZ
cord-008530-yni0poh9	205	9	IL-8	IL-8	NNP
cord-008530-yni0poh9	205	10	as	as	RB
cord-008530-yni0poh9	205	11	well	well	RB
cord-008530-yni0poh9	205	12	as	as	IN
cord-008530-yni0poh9	205	13	the	the	DT
cord-008530-yni0poh9	205	14	other	other	JJ
cord-008530-yni0poh9	205	15	ELR	ELR	NNP
cord-008530-yni0poh9	205	16	CXC	CXC	NNP
cord-008530-yni0poh9	205	17	chemokines	chemokine	NNS
cord-008530-yni0poh9	205	18	,	,	,
cord-008530-yni0poh9	205	19	GRO-(z	GRO-(z	NNP
cord-008530-yni0poh9	205	20	and	and	CC
cord-008530-yni0poh9	206	1	PF-4	PF-4	NNP
cord-008530-yni0poh9	206	2	(	(	-LRB-
cord-008530-yni0poh9	206	3	Ahuja	Ahuja	NNP
cord-008530-yni0poh9	206	4	and	and	CC
cord-008530-yni0poh9	206	5	Murphy	Murphy	NNP
cord-008530-yni0poh9	206	6	,	,	,
cord-008530-yni0poh9	206	7	1993	1993	CD
cord-008530-yni0poh9	206	8	)	)	-RRB-
cord-008530-yni0poh9	206	9	.	.	.
cord-008530-yni0poh9	207	1	However	however	RB
cord-008530-yni0poh9	207	2	unlike	unlike	IN
cord-008530-yni0poh9	207	3	CXCR1	cxcr1	NN
cord-008530-yni0poh9	207	4	and	and	CC
cord-008530-yni0poh9	207	5	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	207	6	,	,	,
cord-008530-yni0poh9	207	7	ORF	ORF	NNP
cord-008530-yni0poh9	207	8	74	74	CD
cord-008530-yni0poh9	207	9	can	can	MD
cord-008530-yni0poh9	207	10	signal	signal	VB
cord-008530-yni0poh9	207	11	in	in	IN
cord-008530-yni0poh9	207	12	a	a	DT
cord-008530-yni0poh9	207	13	constitutive	constitutive	JJ
cord-008530-yni0poh9	207	14	agonist	agonist	NN
cord-008530-yni0poh9	207	15	-	-	HYPH
cord-008530-yni0poh9	207	16	independent	independent	JJ
cord-008530-yni0poh9	207	17	manner	manner	NN
cord-008530-yni0poh9	207	18	and	and	CC
cord-008530-yni0poh9	207	19	stimulate	stimulate	VB
cord-008530-yni0poh9	207	20	the	the	DT
cord-008530-yni0poh9	207	21	proliferation	proliferation	NN
cord-008530-yni0poh9	207	22	of	of	IN
cord-008530-yni0poh9	207	23	kidney	kidney	NN
cord-008530-yni0poh9	207	24	fibroblasts	fibroblast	NNS
cord-008530-yni0poh9	207	25	(	(	-LRB-
cord-008530-yni0poh9	207	26	Arvanitakis	Arvanitakis	NNP
cord-008530-yni0poh9	207	27	et	et	NNP
cord-008530-yni0poh9	207	28	al	al	NNP
cord-008530-yni0poh9	207	29	.	.	NNP
cord-008530-yni0poh9	207	30	,	,	,
cord-008530-yni0poh9	207	31	1997	1997	CD
cord-008530-yni0poh9	207	32	)	)	-RRB-
cord-008530-yni0poh9	207	33	.	.	.
cord-008530-yni0poh9	208	1	In	in	IN
cord-008530-yni0poh9	208	2	addition	addition	NN
cord-008530-yni0poh9	208	3	to	to	IN
cord-008530-yni0poh9	208	4	the	the	DT
cord-008530-yni0poh9	208	5	stimulation	stimulation	NN
cord-008530-yni0poh9	208	6	of	of	IN
cord-008530-yni0poh9	208	7	proliferation	proliferation	NN
cord-008530-yni0poh9	208	8	of	of	IN
cord-008530-yni0poh9	208	9	nontransformed	nontransforme	VBN
cord-008530-yni0poh9	208	10	cells	cell	NNS
cord-008530-yni0poh9	208	11	,	,	,
cord-008530-yni0poh9	208	12	ORF	ORF	NNP
cord-008530-yni0poh9	208	13	74	74	CD
cord-008530-yni0poh9	208	14	signaling	signal	VBG
cord-008530-yni0poh9	208	15	may	may	MD
cord-008530-yni0poh9	208	16	also	also	RB
cord-008530-yni0poh9	208	17	lead	lead	VB
cord-008530-yni0poh9	208	18	to	to	IN
cord-008530-yni0poh9	208	19	cellular	cellular	JJ
cord-008530-yni0poh9	208	20	transformation	transformation	NN
cord-008530-yni0poh9	208	21	and	and	CC
cord-008530-yni0poh9	208	22	tumorigenicity	tumorigenicity	NN
cord-008530-yni0poh9	208	23	(	(	-LRB-
cord-008530-yni0poh9	208	24	Bais	Bais	NNP
cord-008530-yni0poh9	208	25	et	et	FW
cord-008530-yni0poh9	208	26	al	al	NNP
cord-008530-yni0poh9	208	27	.	.	NNP
cord-008530-yni0poh9	208	28	,	,	,
cord-008530-yni0poh9	208	29	1998	1998	CD
cord-008530-yni0poh9	208	30	)	)	-RRB-
cord-008530-yni0poh9	208	31	.	.	.
cord-008530-yni0poh9	209	1	Thus	thus	RB
cord-008530-yni0poh9	209	2	,	,	,
cord-008530-yni0poh9	209	3	it	-PRON-	PRP
cord-008530-yni0poh9	209	4	would	would	MD
cord-008530-yni0poh9	209	5	appear	appear	VB
cord-008530-yni0poh9	209	6	that	that	IN
cord-008530-yni0poh9	209	7	ORF	ORF	NNP
cord-008530-yni0poh9	209	8	74	74	CD
cord-008530-yni0poh9	209	9	may	may	MD
cord-008530-yni0poh9	209	10	contribute	contribute	VB
cord-008530-yni0poh9	209	11	to	to	IN
cord-008530-yni0poh9	209	12	the	the	DT
cord-008530-yni0poh9	209	13	development	development	NN
cord-008530-yni0poh9	209	14	of	of	IN
cord-008530-yni0poh9	209	15	the	the	DT
cord-008530-yni0poh9	209	16	transformed	transform	VBN
cord-008530-yni0poh9	209	17	cell	cell	NN
cord-008530-yni0poh9	209	18	phenotype	phenotype	NN
cord-008530-yni0poh9	209	19	found	find	VBN
cord-008530-yni0poh9	209	20	with	with	IN
cord-008530-yni0poh9	209	21	KSHV	KSHV	NNP
cord-008530-yni0poh9	209	22	-	-	HYPH
cord-008530-yni0poh9	209	23	infected	infect	VBN
cord-008530-yni0poh9	209	24	cells	cell	NNS
cord-008530-yni0poh9	209	25	in	in	IN
cord-008530-yni0poh9	209	26	Kaposi	Kaposi	NNP
cord-008530-yni0poh9	209	27	's	's	POS
cord-008530-yni0poh9	209	28	sarcoma	sarcoma	NN
cord-008530-yni0poh9	209	29	lesions	lesion	NNS
cord-008530-yni0poh9	209	30	.	.	.
cord-008530-yni0poh9	210	1	Cytomegalovirus	Cytomegalovirus	NNP
cord-008530-yni0poh9	210	2	(	(	-LRB-
cord-008530-yni0poh9	210	3	CMV	CMV	NNP
cord-008530-yni0poh9	210	4	)	)	-RRB-
cord-008530-yni0poh9	210	5	is	be	VBZ
cord-008530-yni0poh9	210	6	a	a	DT
cord-008530-yni0poh9	210	7	common	common	JJ
cord-008530-yni0poh9	210	8	opportunistic	opportunistic	JJ
cord-008530-yni0poh9	210	9	pathogen	pathogen	NN
cord-008530-yni0poh9	210	10	of	of	IN
cord-008530-yni0poh9	210	11	immunocompromised	immunocompromised	JJ
cord-008530-yni0poh9	210	12	hosts	host	NNS
cord-008530-yni0poh9	210	13	in	in	IN
cord-008530-yni0poh9	210	14	whom	whom	WP
cord-008530-yni0poh9	210	15	the	the	DT
cord-008530-yni0poh9	210	16	virus	virus	NN
cord-008530-yni0poh9	210	17	exhibits	exhibit	VBZ
cord-008530-yni0poh9	210	18	tropism	tropism	NN
cord-008530-yni0poh9	210	19	for	for	IN
cord-008530-yni0poh9	210	20	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	210	21	.	.	.
cord-008530-yni0poh9	211	1	Human	human	JJ
cord-008530-yni0poh9	211	2	and	and	CC
cord-008530-yni0poh9	211	3	murine	murine	JJ
cord-008530-yni0poh9	211	4	CMV	CMV	NNP
cord-008530-yni0poh9	211	5	possess	possess	VBP
cord-008530-yni0poh9	211	6	genes	gene	NNS
cord-008530-yni0poh9	211	7	that	that	WDT
cord-008530-yni0poh9	211	8	encode	encode	VBP
cord-008530-yni0poh9	211	9	a	a	DT
cord-008530-yni0poh9	211	10	variety	variety	NN
cord-008530-yni0poh9	211	11	of	of	IN
cord-008530-yni0poh9	211	12	chemokine	chemokine	NN
cord-008530-yni0poh9	211	13	homologs	homolog	NNS
cord-008530-yni0poh9	212	1	(	(	-LRB-
cord-008530-yni0poh9	212	2	MacDonald	MacDonald	NNP
cord-008530-yni0poh9	212	3	et	et	NNP
cord-008530-yni0poh9	212	4	al	al	NNP
cord-008530-yni0poh9	212	5	.	.	NNP
cord-008530-yni0poh9	212	6	,	,	,
cord-008530-yni0poh9	212	7	1997	1997	CD
cord-008530-yni0poh9	212	8	)	)	-RRB-
cord-008530-yni0poh9	212	9	.	.	.
cord-008530-yni0poh9	213	1	The	the	DT
cord-008530-yni0poh9	213	2	murine	murine	JJ
cord-008530-yni0poh9	213	3	CMV	CMV	NNP
cord-008530-yni0poh9	213	4	chemokine	chemokine	NN
cord-008530-yni0poh9	213	5	1	1	CD
cord-008530-yni0poh9	213	6	and	and	CC
cord-008530-yni0poh9	213	7	2	2	CD
cord-008530-yni0poh9	214	1	(	(	-LRB-
cord-008530-yni0poh9	214	2	MCK-1	MCK-1	NNP
cord-008530-yni0poh9	214	3	and	and	CC
cord-008530-yni0poh9	214	4	MCK-2	MCK-2	NNP
cord-008530-yni0poh9	214	5	)	)	-RRB-
cord-008530-yni0poh9	214	6	peptides	peptide	NNS
cord-008530-yni0poh9	214	7	induce	induce	VBP
cord-008530-yni0poh9	214	8	calcium	calcium	NN
cord-008530-yni0poh9	214	9	signaling	signaling	NN
cord-008530-yni0poh9	214	10	and	and	CC
cord-008530-yni0poh9	214	11	adherence	adherence	NN
cord-008530-yni0poh9	214	12	in	in	IN
cord-008530-yni0poh9	214	13	peritoneal	peritoneal	JJ
cord-008530-yni0poh9	214	14	macrophages	macrophage	NNS
cord-008530-yni0poh9	214	15	(	(	-LRB-
cord-008530-yni0poh9	214	16	Saederup	Saederup	NNP
cord-008530-yni0poh9	214	17	et	et	NNP
cord-008530-yni0poh9	214	18	al	al	NNP
cord-008530-yni0poh9	214	19	.	.	NNP
cord-008530-yni0poh9	214	20	,	,	,
cord-008530-yni0poh9	214	21	1999	1999	CD
cord-008530-yni0poh9	214	22	)	)	-RRB-
cord-008530-yni0poh9	214	23	.	.	.
cord-008530-yni0poh9	215	1	The	the	DT
cord-008530-yni0poh9	215	2	human	human	JJ
cord-008530-yni0poh9	215	3	CMV	CMV	NNP
cord-008530-yni0poh9	215	4	gene	gene	NN
cord-008530-yni0poh9	215	5	UL146	UL146	NNP
cord-008530-yni0poh9	215	6	encodes	encode	VBZ
cord-008530-yni0poh9	215	7	a	a	DT
cord-008530-yni0poh9	215	8	protein	protein	NN
cord-008530-yni0poh9	215	9	designated	designate	VBN
cord-008530-yni0poh9	215	10	as	as	IN
cord-008530-yni0poh9	215	11	vCXC-1	vCXC-1	:
cord-008530-yni0poh9	215	12	and	and	CC
cord-008530-yni0poh9	215	13	provides	provide	VBZ
cord-008530-yni0poh9	215	14	the	the	DT
cord-008530-yni0poh9	215	15	first	first	JJ
cord-008530-yni0poh9	215	16	example	example	NN
cord-008530-yni0poh9	215	17	of	of	IN
cord-008530-yni0poh9	215	18	a	a	DT
cord-008530-yni0poh9	215	19	virus	virus	NN
cord-008530-yni0poh9	215	20	-	-	HYPH
cord-008530-yni0poh9	215	21	encoded	encode	VBN
cord-008530-yni0poh9	215	22	CXC	CXC	NNP
cord-008530-yni0poh9	215	23	chemokine	chemokine	NN
cord-008530-yni0poh9	215	24	(	(	-LRB-
cord-008530-yni0poh9	215	25	Penfold	Penfold	NNP
cord-008530-yni0poh9	215	26	et	et	NNP
cord-008530-yni0poh9	215	27	al	al	NNP
cord-008530-yni0poh9	215	28	.	.	NNP
cord-008530-yni0poh9	215	29	,	,	,
cord-008530-yni0poh9	215	30	1999	1999	CD
cord-008530-yni0poh9	215	31	)	)	-RRB-
cord-008530-yni0poh9	215	32	.	.	.
cord-008530-yni0poh9	216	1	The	the	DT
cord-008530-yni0poh9	216	2	vCXC-1	vCXC-1	JJS
cord-008530-yni0poh9	216	3	glycoprotein	glycoprotein	NN
cord-008530-yni0poh9	216	4	shows	show	VBZ
cord-008530-yni0poh9	216	5	high	high	JJ
cord-008530-yni0poh9	216	6	-	-	HYPH
cord-008530-yni0poh9	216	7	affinity	affinity	NN
cord-008530-yni0poh9	216	8	binding	binding	NN
cord-008530-yni0poh9	216	9	to	to	IN
cord-008530-yni0poh9	216	10	the	the	DT
cord-008530-yni0poh9	216	11	CXCR1	CXCR1	NNS
cord-008530-yni0poh9	216	12	and	and	CC
cord-008530-yni0poh9	216	13	CXCR2	cxcr2	NN
cord-008530-yni0poh9	216	14	chemokine	chemokine	NN
cord-008530-yni0poh9	216	15	receptors	receptor	NNS
cord-008530-yni0poh9	216	16	,	,	,
cord-008530-yni0poh9	216	17	inducing	induce	VBG
cord-008530-yni0poh9	216	18	calcium	calcium	NN
cord-008530-yni0poh9	216	19	mobilization	mobilization	NN
cord-008530-yni0poh9	216	20	and	and	CC
cord-008530-yni0poh9	216	21	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	216	22	of	of	IN
cord-008530-yni0poh9	216	23	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	216	24	.	.	.
cord-008530-yni0poh9	217	1	Thus	thus	RB
cord-008530-yni0poh9	217	2	,	,	,
cord-008530-yni0poh9	217	3	the	the	DT
cord-008530-yni0poh9	217	4	common	common	JJ
cord-008530-yni0poh9	217	5	property	property	NN
cord-008530-yni0poh9	217	6	of	of	IN
cord-008530-yni0poh9	217	7	the	the	DT
cord-008530-yni0poh9	217	8	CMV	CMV	NNP
cord-008530-yni0poh9	217	9	chemokine	chemokine	NN
cord-008530-yni0poh9	217	10	homologs	homolog	NNS
cord-008530-yni0poh9	217	11	is	be	VBZ
cord-008530-yni0poh9	217	12	to	to	TO
cord-008530-yni0poh9	217	13	function	function	VB
cord-008530-yni0poh9	217	14	as	as	IN
cord-008530-yni0poh9	217	15	chemokine	chemokine	NN
cord-008530-yni0poh9	217	16	agonists	agonist	NNS
cord-008530-yni0poh9	217	17	.	.	.
cord-008530-yni0poh9	218	1	This	this	DT
cord-008530-yni0poh9	218	2	in	in	IN
cord-008530-yni0poh9	218	3	turn	turn	NN
cord-008530-yni0poh9	218	4	may	may	MD
cord-008530-yni0poh9	218	5	promote	promote	VB
cord-008530-yni0poh9	218	6	leukocyte	leukocyte	NN
cord-008530-yni0poh9	218	7	migration	migration	NN
cord-008530-yni0poh9	218	8	to	to	IN
cord-008530-yni0poh9	218	9	sites	site	NNS
cord-008530-yni0poh9	218	10	of	of	IN
cord-008530-yni0poh9	218	11	infection	infection	NN
cord-008530-yni0poh9	218	12	and	and	CC
cord-008530-yni0poh9	218	13	may	may	MD
cord-008530-yni0poh9	218	14	be	be	VB
cord-008530-yni0poh9	218	15	responsible	responsible	JJ
cord-008530-yni0poh9	218	16	for	for	IN
cord-008530-yni0poh9	218	17	more	more	RBR
cord-008530-yni0poh9	218	18	efficient	efficient	JJ
cord-008530-yni0poh9	218	19	dissemination	dissemination	NN
cord-008530-yni0poh9	218	20	of	of	IN
cord-008530-yni0poh9	218	21	CMV	CMV	NNP
cord-008530-yni0poh9	218	22	in	in	IN
cord-008530-yni0poh9	218	23	the	the	DT
cord-008530-yni0poh9	218	24	host	host	NN
cord-008530-yni0poh9	218	25	.	.	.
cord-008530-yni0poh9	219	1	In	in	IN
cord-008530-yni0poh9	219	2	support	support	NN
cord-008530-yni0poh9	219	3	of	of	IN
cord-008530-yni0poh9	219	4	this	this	DT
cord-008530-yni0poh9	219	5	notion	notion	NN
cord-008530-yni0poh9	219	6	,	,	,
cord-008530-yni0poh9	219	7	MCK-1	MCK-1	NNP
cord-008530-yni0poh9	219	8	/	/	SYM
cord-008530-yni0poh9	219	9	MCK-2	MCK-2	NNP
cord-008530-yni0poh9	219	10	mutant	mutant	JJ
cord-008530-yni0poh9	219	11	CMV	CMV	NNP
cord-008530-yni0poh9	219	12	displays	display	NNS
cord-008530-yni0poh9	219	13	markedly	markedly	RB
cord-008530-yni0poh9	219	14	reduced	reduce	VBN
cord-008530-yni0poh9	219	15	peak	peak	NN
cord-008530-yni0poh9	219	16	levels	level	NNS
cord-008530-yni0poh9	219	17	of	of	IN
cord-008530-yni0poh9	219	18	monocyte	monocyte	NNP
cord-008530-yni0poh9	219	19	-	-	HYPH
cord-008530-yni0poh9	219	20	associated	associate	VBN
cord-008530-yni0poh9	219	21	viremia	viremia	NN
cord-008530-yni0poh9	219	22	in	in	IN
cord-008530-yni0poh9	219	23	experimentally	experimentally	RB
cord-008530-yni0poh9	219	24	infected	infect	VBN
cord-008530-yni0poh9	219	25	mice	mouse	NNS
cord-008530-yni0poh9	220	1	(	(	-LRB-
cord-008530-yni0poh9	220	2	Saederup	Saederup	NNP
cord-008530-yni0poh9	220	3	et	et	NNP
cord-008530-yni0poh9	220	4	al	al	NNP
cord-008530-yni0poh9	220	5	.	.	NNP
cord-008530-yni0poh9	220	6	,	,	,
cord-008530-yni0poh9	220	7	1999	1999	CD
cord-008530-yni0poh9	220	8	)	)	-RRB-
cord-008530-yni0poh9	220	9	.	.	.
cord-008530-yni0poh9	221	1	A	a	DT
cord-008530-yni0poh9	221	2	gene	gene	NN
cord-008530-yni0poh9	221	3	encoding	encode	VBG
cord-008530-yni0poh9	221	4	a	a	DT
cord-008530-yni0poh9	221	5	viral	viral	JJ
cord-008530-yni0poh9	221	6	homolog	homolog	NN
cord-008530-yni0poh9	221	7	of	of	IN
cord-008530-yni0poh9	221	8	CCR1	CCR1	NNP
cord-008530-yni0poh9	221	9	was	be	VBD
cord-008530-yni0poh9	221	10	found	find	VBN
cord-008530-yni0poh9	221	11	within	within	IN
cord-008530-yni0poh9	221	12	the	the	DT
cord-008530-yni0poh9	221	13	genome	genome	NN
cord-008530-yni0poh9	221	14	of	of	IN
cord-008530-yni0poh9	221	15	the	the	DT
cord-008530-yni0poh9	221	16	human	human	JJ
cord-008530-yni0poh9	221	17	CMV	CMV	NNP
cord-008530-yni0poh9	221	18	.	.	.
cord-008530-yni0poh9	222	1	This	this	DT
cord-008530-yni0poh9	222	2	gene	gene	NN
cord-008530-yni0poh9	222	3	,	,	,
cord-008530-yni0poh9	222	4	ORF	ORF	NNP
cord-008530-yni0poh9	222	5	US28	US28	NNP
cord-008530-yni0poh9	222	6	,	,	,
cord-008530-yni0poh9	222	7	of	of	IN
cord-008530-yni0poh9	222	8	human	human	JJ
cord-008530-yni0poh9	222	9	cytomegalovirus	cytomegalovirus	NN
cord-008530-yni0poh9	222	10	(	(	-LRB-
cord-008530-yni0poh9	222	11	HCMV	HCMV	NNP
cord-008530-yni0poh9	222	12	)	)	-RRB-
cord-008530-yni0poh9	222	13	was	be	VBD
cord-008530-yni0poh9	222	14	shown	show	VBN
cord-008530-yni0poh9	222	15	to	to	TO
cord-008530-yni0poh9	222	16	bind	bind	VB
cord-008530-yni0poh9	222	17	MIP	MIP	NNP
cord-008530-yni0poh9	222	18	-	-	HYPH
cord-008530-yni0poh9	222	19	la,-~	la,-~	NNP
cord-008530-yni0poh9	222	20	,	,	,
cord-008530-yni0poh9	222	21	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	222	22	,	,	,
cord-008530-yni0poh9	222	23	RANTES	RANTES	NNP
cord-008530-yni0poh9	222	24	,	,	,
cord-008530-yni0poh9	222	25	and	and	CC
cord-008530-yni0poh9	222	26	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	223	1	(	(	-LRB-
cord-008530-yni0poh9	223	2	Bodaghi	Bodaghi	NNP
cord-008530-yni0poh9	223	3	et	et	NNP
cord-008530-yni0poh9	223	4	al	al	NNP
cord-008530-yni0poh9	223	5	.	.	NNP
cord-008530-yni0poh9	223	6	,	,	,
cord-008530-yni0poh9	223	7	1998	1998	CD
cord-008530-yni0poh9	223	8	)	)	-RRB-
cord-008530-yni0poh9	223	9	with	with	IN
cord-008530-yni0poh9	223	10	higher	high	JJR
cord-008530-yni0poh9	223	11	affinity	affinity	NN
cord-008530-yni0poh9	223	12	than	than	IN
cord-008530-yni0poh9	223	13	their	-PRON-	PRP$
cord-008530-yni0poh9	223	14	cognate	cognate	JJ
cord-008530-yni0poh9	223	15	receptors	receptor	NNS
cord-008530-yni0poh9	223	16	.	.	.
cord-008530-yni0poh9	224	1	Thus	thus	RB
cord-008530-yni0poh9	224	2	,	,	,
cord-008530-yni0poh9	224	3	it	-PRON-	PRP
cord-008530-yni0poh9	224	4	is	be	VBZ
cord-008530-yni0poh9	224	5	attractive	attractive	JJ
cord-008530-yni0poh9	224	6	to	to	TO
cord-008530-yni0poh9	224	7	speculate	speculate	VB
cord-008530-yni0poh9	224	8	that	that	IN
cord-008530-yni0poh9	224	9	HCMV	HCMV	NNP
cord-008530-yni0poh9	224	10	-	-	HYPH
cord-008530-yni0poh9	224	11	infected	infect	VBN
cord-008530-yni0poh9	224	12	cells	cell	NNS
cord-008530-yni0poh9	224	13	expressing	express	VBG
cord-008530-yni0poh9	224	14	US28	US28	NNP
cord-008530-yni0poh9	224	15	may	may	MD
cord-008530-yni0poh9	224	16	be	be	VB
cord-008530-yni0poh9	224	17	used	use	VBN
cord-008530-yni0poh9	224	18	for	for	IN
cord-008530-yni0poh9	224	19	sequestration	sequestration	NN
cord-008530-yni0poh9	224	20	of	of	IN
cord-008530-yni0poh9	224	21	chemokines	chemokine	NNS
cord-008530-yni0poh9	224	22	from	from	IN
cord-008530-yni0poh9	224	23	the	the	DT
cord-008530-yni0poh9	224	24	extracellular	extracellular	JJ
cord-008530-yni0poh9	224	25	milieu	milieu	NN
cord-008530-yni0poh9	224	26	.	.	.
cord-008530-yni0poh9	225	1	US28	US28	NNS
cord-008530-yni0poh9	225	2	can	can	MD
cord-008530-yni0poh9	225	3	also	also	RB
cord-008530-yni0poh9	225	4	serve	serve	VB
cord-008530-yni0poh9	225	5	as	as	IN
cord-008530-yni0poh9	225	6	a	a	DT
cord-008530-yni0poh9	225	7	coreceptor	coreceptor	NN
cord-008530-yni0poh9	225	8	for	for	IN
cord-008530-yni0poh9	225	9	HIV	HIV	NNP
cord-008530-yni0poh9	225	10	infection	infection	NN
cord-008530-yni0poh9	225	11	of	of	IN
cord-008530-yni0poh9	225	12	CD4	CD4	NNP
cord-008530-yni0poh9	225	13	T	T	NNP
cord-008530-yni0poh9	225	14	cells	cell	NNS
cord-008530-yni0poh9	225	15	and	and	CC
cord-008530-yni0poh9	225	16	may	may	MD
cord-008530-yni0poh9	225	17	facilitate	facilitate	VB
cord-008530-yni0poh9	225	18	an	an	DT
cord-008530-yni0poh9	225	19	interplay	interplay	NN
cord-008530-yni0poh9	225	20	between	between	IN
cord-008530-yni0poh9	225	21	HIV	HIV	NNP
cord-008530-yni0poh9	225	22	and	and	CC
cord-008530-yni0poh9	225	23	HCMV	HCMV	NNP
cord-008530-yni0poh9	225	24	(	(	-LRB-
cord-008530-yni0poh9	225	25	Pleskoffet	Pleskoffet	NNP
cord-008530-yni0poh9	225	26	al	al	NNP
cord-008530-yni0poh9	225	27	.	.	NNP
cord-008530-yni0poh9	225	28	,	,	,
cord-008530-yni0poh9	225	29	1997	1997	CD
cord-008530-yni0poh9	225	30	)	)	-RRB-
cord-008530-yni0poh9	225	31	.	.	.
cord-008530-yni0poh9	226	1	The	the	DT
cord-008530-yni0poh9	226	2	poxvirus	poxvirus	NNP
cord-008530-yni0poh9	226	3	molluscum	molluscum	NN
cord-008530-yni0poh9	226	4	contagiosum	contagiosum	NN
cord-008530-yni0poh9	226	5	virus	virus	NN
cord-008530-yni0poh9	226	6	(	(	-LRB-
cord-008530-yni0poh9	226	7	MCV	MCV	NNP
cord-008530-yni0poh9	226	8	)	)	-RRB-
cord-008530-yni0poh9	226	9	infects	infect	VBZ
cord-008530-yni0poh9	226	10	humans	human	NNS
cord-008530-yni0poh9	226	11	,	,	,
cord-008530-yni0poh9	226	12	causing	cause	VBG
cord-008530-yni0poh9	226	13	papules	papule	NNS
cord-008530-yni0poh9	226	14	of	of	IN
cord-008530-yni0poh9	226	15	the	the	DT
cord-008530-yni0poh9	226	16	skin	skin	NN
cord-008530-yni0poh9	226	17	associated	associate	VBN
cord-008530-yni0poh9	226	18	with	with	IN
cord-008530-yni0poh9	226	19	virtually	virtually	RB
cord-008530-yni0poh9	226	20	no	no	DT
cord-008530-yni0poh9	226	21	immune	immune	JJ
cord-008530-yni0poh9	226	22	response	response	NN
cord-008530-yni0poh9	226	23	to	to	IN
cord-008530-yni0poh9	226	24	the	the	DT
cord-008530-yni0poh9	226	25	virus	virus	NN
cord-008530-yni0poh9	226	26	in	in	IN
cord-008530-yni0poh9	226	27	the	the	DT
cord-008530-yni0poh9	226	28	skin	skin	NN
cord-008530-yni0poh9	226	29	lesion	lesion	NN
cord-008530-yni0poh9	226	30	.	.	.
cord-008530-yni0poh9	227	1	The	the	DT
cord-008530-yni0poh9	227	2	genome	genome	NN
cord-008530-yni0poh9	227	3	of	of	IN
cord-008530-yni0poh9	227	4	MCV	MCV	NNP
cord-008530-yni0poh9	227	5	contains	contain	VBZ
cord-008530-yni0poh9	227	6	an	an	DT
cord-008530-yni0poh9	227	7	ORF	ORF	NNP
cord-008530-yni0poh9	227	8	that	that	WDT
cord-008530-yni0poh9	227	9	encodes	encode	VBZ
cord-008530-yni0poh9	227	10	a	a	DT
cord-008530-yni0poh9	227	11	protein	protein	NN
cord-008530-yni0poh9	227	12	(	(	-LRB-
cord-008530-yni0poh9	227	13	MC148R	mc148r	NN
cord-008530-yni0poh9	227	14	)	)	-RRB-
cord-008530-yni0poh9	228	1	that	that	DT
cord-008530-yni0poh9	228	2	is	be	VBZ
cord-008530-yni0poh9	228	3	a	a	DT
cord-008530-yni0poh9	228	4	CC	cc	NN
cord-008530-yni0poh9	228	5	chemokine	chemokine	NN
cord-008530-yni0poh9	228	6	homolog	homolog	NN
cord-008530-yni0poh9	228	7	(	(	-LRB-
cord-008530-yni0poh9	228	8	Senkevich	Senkevich	NNP
cord-008530-yni0poh9	228	9	et	et	NNP
cord-008530-yni0poh9	228	10	al	al	NNP
cord-008530-yni0poh9	228	11	.	.	NNP
cord-008530-yni0poh9	228	12	,	,	,
cord-008530-yni0poh9	228	13	1996	1996	CD
cord-008530-yni0poh9	228	14	)	)	-RRB-
cord-008530-yni0poh9	228	15	.	.	.
cord-008530-yni0poh9	229	1	MC148R	MC148R	NNP
cord-008530-yni0poh9	229	2	has	have	VBZ
cord-008530-yni0poh9	229	3	homology	homology	NN
cord-008530-yni0poh9	229	4	to	to	IN
cord-008530-yni0poh9	229	5	MIP	MIP	NNP
cord-008530-yni0poh9	229	6	-	-	HYPH
cord-008530-yni0poh9	229	7	la/[3	la/[3	ADD
cord-008530-yni0poh9	230	1	but	but	CC
cord-008530-yni0poh9	230	2	does	do	VBZ
cord-008530-yni0poh9	230	3	not	not	RB
cord-008530-yni0poh9	230	4	induce	induce	VB
cord-008530-yni0poh9	230	5	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	230	6	and	and	CC
cord-008530-yni0poh9	230	7	antagonizes	antagonize	VBZ
cord-008530-yni0poh9	230	8	MIP	MIP	NNP
cord-008530-yni0poh9	230	9	-	-	HYPH
cord-008530-yni0poh9	230	10	la	la	NN
cord-008530-yni0poh9	230	11	-	-	HYPH
cord-008530-yni0poh9	230	12	induced	induce	VBN
cord-008530-yni0poh9	230	13	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	230	14	(	(	-LRB-
cord-008530-yni0poh9	230	15	Krathwohl	Krathwohl	NNP
cord-008530-yni0poh9	230	16	et	et	FW
cord-008530-yni0poh9	230	17	al	al	NNP
cord-008530-yni0poh9	230	18	.	.	NNP
cord-008530-yni0poh9	230	19	,	,	,
cord-008530-yni0poh9	230	20	1997	1997	CD
cord-008530-yni0poh9	230	21	)	)	-RRB-
cord-008530-yni0poh9	230	22	.	.	.
cord-008530-yni0poh9	231	1	Furthermore	furthermore	RB
cord-008530-yni0poh9	231	2	,	,	,
cord-008530-yni0poh9	231	3	MC148R	MC148R	NNP
cord-008530-yni0poh9	231	4	inhibits	inhibit	VBZ
cord-008530-yni0poh9	231	5	the	the	DT
cord-008530-yni0poh9	231	6	leukocyte	leukocyte	NN
cord-008530-yni0poh9	231	7	response	response	NN
cord-008530-yni0poh9	231	8	to	to	IN
cord-008530-yni0poh9	231	9	several	several	JJ
cord-008530-yni0poh9	231	10	CC	CC	NNP
cord-008530-yni0poh9	231	11	and	and	CC
cord-008530-yni0poh9	231	12	CXC	CXC	NNP
cord-008530-yni0poh9	231	13	chemokines	chemokine	NNS
cord-008530-yni0poh9	232	1	(	(	-LRB-
cord-008530-yni0poh9	232	2	Damon	Damon	NNP
cord-008530-yni0poh9	232	3	et	et	NNP
cord-008530-yni0poh9	232	4	al	al	NNP
cord-008530-yni0poh9	232	5	.	.	.
cord-008530-yni0poh9	233	1	,	,	,
cord-008530-yni0poh9	233	2	1998	1998	CD
cord-008530-yni0poh9	233	3	)	)	-RRB-
cord-008530-yni0poh9	233	4	,	,	,
cord-008530-yni0poh9	233	5	indicating	indicate	VBG
cord-008530-yni0poh9	233	6	that	that	IN
cord-008530-yni0poh9	233	7	it	-PRON-	PRP
cord-008530-yni0poh9	233	8	can	can	MD
cord-008530-yni0poh9	233	9	act	act	VB
cord-008530-yni0poh9	233	10	as	as	IN
cord-008530-yni0poh9	233	11	a	a	DT
cord-008530-yni0poh9	233	12	broad	broad	JJ
cord-008530-yni0poh9	233	13	-	-	HYPH
cord-008530-yni0poh9	233	14	spectrum	spectrum	NN
cord-008530-yni0poh9	233	15	chemokine	chemokine	NN
cord-008530-yni0poh9	233	16	antagonist	antagonist	NN
cord-008530-yni0poh9	233	17	.	.	.
cord-008530-yni0poh9	234	1	Therefore	therefore	RB
cord-008530-yni0poh9	234	2	,	,	,
cord-008530-yni0poh9	234	3	a	a	DT
cord-008530-yni0poh9	234	4	primary	primary	JJ
cord-008530-yni0poh9	234	5	function	function	NN
cord-008530-yni0poh9	234	6	of	of	IN
cord-008530-yni0poh9	234	7	this	this	DT
cord-008530-yni0poh9	234	8	virus	virus	NN
cord-008530-yni0poh9	234	9	-	-	HYPH
cord-008530-yni0poh9	234	10	encoded	encode	VBN
cord-008530-yni0poh9	234	11	chemokine	chemokine	NN
cord-008530-yni0poh9	234	12	homolog	homolog	NN
cord-008530-yni0poh9	234	13	might	may	MD
cord-008530-yni0poh9	234	14	be	be	VB
cord-008530-yni0poh9	234	15	to	to	TO
cord-008530-yni0poh9	234	16	provide	provide	VB
cord-008530-yni0poh9	234	17	an	an	DT
cord-008530-yni0poh9	234	18	immune	immune	JJ
cord-008530-yni0poh9	234	19	evasion	evasion	NN
cord-008530-yni0poh9	234	20	strategy	strategy	NN
cord-008530-yni0poh9	234	21	that	that	WDT
cord-008530-yni0poh9	234	22	acts	act	VBZ
cord-008530-yni0poh9	234	23	to	to	TO
cord-008530-yni0poh9	234	24	limit	limit	VB
cord-008530-yni0poh9	234	25	the	the	DT
cord-008530-yni0poh9	234	26	recruitment	recruitment	NN
cord-008530-yni0poh9	234	27	of	of	IN
cord-008530-yni0poh9	234	28	effector	effector	JJ
cord-008530-yni0poh9	234	29	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	234	30	to	to	IN
cord-008530-yni0poh9	234	31	MCVinfected	mcvinfected	JJ
cord-008530-yni0poh9	234	32	epidermal	epidermal	JJ
cord-008530-yni0poh9	234	33	cells	cell	NNS
cord-008530-yni0poh9	234	34	.	.	.
cord-008530-yni0poh9	235	1	In	in	IN
cord-008530-yni0poh9	235	2	conclusion	conclusion	NN
cord-008530-yni0poh9	235	3	,	,	,
cord-008530-yni0poh9	235	4	unquestionably	unquestionably	RB
cord-008530-yni0poh9	235	5	these	these	DT
cord-008530-yni0poh9	235	6	large	large	JJ
cord-008530-yni0poh9	235	7	DNA	dna	NN
cord-008530-yni0poh9	235	8	viruses	virus	NNS
cord-008530-yni0poh9	235	9	encode	encode	VBP
cord-008530-yni0poh9	235	10	functional	functional	JJ
cord-008530-yni0poh9	235	11	homologs	homolog	NNS
cord-008530-yni0poh9	235	12	of	of	IN
cord-008530-yni0poh9	235	13	chemokines	chemokine	NNS
cord-008530-yni0poh9	235	14	and	and	CC
cord-008530-yni0poh9	235	15	chemokine	chemokine	NN
cord-008530-yni0poh9	235	16	receptors	receptor	NNS
cord-008530-yni0poh9	235	17	.	.	.
cord-008530-yni0poh9	236	1	Although	although	IN
cord-008530-yni0poh9	236	2	the	the	DT
cord-008530-yni0poh9	236	3	precise	precise	JJ
cord-008530-yni0poh9	236	4	role	role	NN
cord-008530-yni0poh9	236	5	of	of	IN
cord-008530-yni0poh9	236	6	the	the	DT
cord-008530-yni0poh9	236	7	viral	viral	JJ
cord-008530-yni0poh9	236	8	chemokine	chemokine	NN
cord-008530-yni0poh9	236	9	and	and	CC
cord-008530-yni0poh9	236	10	chemokine	chemokine	NN
cord-008530-yni0poh9	236	11	receptor	receptor	NN
cord-008530-yni0poh9	236	12	homologs	homolog	NNS
cord-008530-yni0poh9	236	13	(	(	-LRB-
cord-008530-yni0poh9	236	14	discussed	discuss	VBN
cord-008530-yni0poh9	236	15	above	above	RB
cord-008530-yni0poh9	236	16	)	)	-RRB-
cord-008530-yni0poh9	236	17	in	in	IN
cord-008530-yni0poh9	236	18	infectious	infectious	JJ
cord-008530-yni0poh9	236	19	processes	process	NNS
cord-008530-yni0poh9	236	20	remains	remain	VBZ
cord-008530-yni0poh9	236	21	to	to	TO
cord-008530-yni0poh9	236	22	be	be	VB
cord-008530-yni0poh9	236	23	determined	determine	VBN
cord-008530-yni0poh9	236	24	,	,	,
cord-008530-yni0poh9	236	25	they	-PRON-	PRP
cord-008530-yni0poh9	236	26	clearly	clearly	RB
cord-008530-yni0poh9	236	27	could	could	MD
cord-008530-yni0poh9	236	28	contribute	contribute	VB
cord-008530-yni0poh9	236	29	to	to	IN
cord-008530-yni0poh9	236	30	the	the	DT
cord-008530-yni0poh9	236	31	strategies	strategy	NNS
cord-008530-yni0poh9	236	32	employed	employ	VBN
cord-008530-yni0poh9	236	33	by	by	IN
cord-008530-yni0poh9	236	34	these	these	DT
cord-008530-yni0poh9	236	35	viruses	virus	NNS
cord-008530-yni0poh9	236	36	to	to	TO
cord-008530-yni0poh9	236	37	subvert	subvert	VB
cord-008530-yni0poh9	236	38	host	host	NN
cord-008530-yni0poh9	236	39	immunity	immunity	NN
cord-008530-yni0poh9	236	40	.	.	.
cord-008530-yni0poh9	237	1	The	the	DT
cord-008530-yni0poh9	237	2	examples	example	NNS
cord-008530-yni0poh9	237	3	discussed	discuss	VBN
cord-008530-yni0poh9	237	4	here	here	RB
cord-008530-yni0poh9	237	5	indicate	indicate	VBP
cord-008530-yni0poh9	237	6	that	that	IN
cord-008530-yni0poh9	237	7	these	these	DT
cord-008530-yni0poh9	237	8	strategies	strategy	NNS
cord-008530-yni0poh9	237	9	are	be	VBP
cord-008530-yni0poh9	237	10	diverse	diverse	JJ
cord-008530-yni0poh9	237	11	and	and	CC
cord-008530-yni0poh9	237	12	,	,	,
cord-008530-yni0poh9	237	13	depending	depend	VBG
cord-008530-yni0poh9	237	14	on	on	IN
cord-008530-yni0poh9	237	15	the	the	DT
cord-008530-yni0poh9	237	16	virus	virus	NN
cord-008530-yni0poh9	237	17	,	,	,
cord-008530-yni0poh9	237	18	range	range	VBP
cord-008530-yni0poh9	237	19	from	from	IN
cord-008530-yni0poh9	237	20	wholesale	wholesale	JJ
cord-008530-yni0poh9	237	21	suppression	suppression	NN
cord-008530-yni0poh9	237	22	of	of	IN
cord-008530-yni0poh9	237	23	leukocyte	leukocyte	NN
cord-008530-yni0poh9	237	24	trafficking	trafficking	NN
cord-008530-yni0poh9	237	25	--	--	:
cord-008530-yni0poh9	237	26	providing	provide	VBG
cord-008530-yni0poh9	237	27	immune	immune	JJ
cord-008530-yni0poh9	237	28	evasion	evasion	NN
cord-008530-yni0poh9	237	29	--	--	:
cord-008530-yni0poh9	237	30	to	to	IN
cord-008530-yni0poh9	237	31	promoting	promote	VBG
cord-008530-yni0poh9	237	32	selective	selective	JJ
cord-008530-yni0poh9	237	33	leukocyte	leukocyte	NN
cord-008530-yni0poh9	237	34	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	237	35	fostering	foster	VBG
cord-008530-yni0poh9	237	36	the	the	DT
cord-008530-yni0poh9	237	37	more	more	RBR
cord-008530-yni0poh9	237	38	efficient	efficient	JJ
cord-008530-yni0poh9	237	39	infection	infection	NN
cord-008530-yni0poh9	237	40	and	and	CC
cord-008530-yni0poh9	237	41	dissemination	dissemination	NN
cord-008530-yni0poh9	237	42	of	of	IN
cord-008530-yni0poh9	237	43	virus	virus	NN
cord-008530-yni0poh9	237	44	via	via	IN
cord-008530-yni0poh9	237	45	its	-PRON-	PRP$
cord-008530-yni0poh9	237	46	preferred	preferred	JJ
cord-008530-yni0poh9	237	47	target	target	NN
cord-008530-yni0poh9	237	48	host	host	NN
cord-008530-yni0poh9	237	49	cell	cell	NN
cord-008530-yni0poh9	237	50	.	.	.
cord-008530-yni0poh9	238	1	A	a	DT
cord-008530-yni0poh9	238	2	concerted	concerted	JJ
cord-008530-yni0poh9	238	3	research	research	NN
cord-008530-yni0poh9	238	4	effort	effort	NN
cord-008530-yni0poh9	238	5	has	have	VBZ
cord-008530-yni0poh9	238	6	been	be	VBN
cord-008530-yni0poh9	238	7	mounted	mount	VBN
cord-008530-yni0poh9	238	8	recently	recently	RB
cord-008530-yni0poh9	238	9	to	to	TO
cord-008530-yni0poh9	238	10	ascertain	ascertain	VB
cord-008530-yni0poh9	238	11	the	the	DT
cord-008530-yni0poh9	238	12	role	role	NN
cord-008530-yni0poh9	238	13	of	of	IN
cord-008530-yni0poh9	238	14	chemokines	chemokine	NNS
cord-008530-yni0poh9	238	15	in	in	IN
cord-008530-yni0poh9	238	16	immunoinflammatory	immunoinflammatory	NNP
cord-008530-yni0poh9	238	17	disorders	disorder	NNS
cord-008530-yni0poh9	238	18	of	of	IN
cord-008530-yni0poh9	238	19	the	the	DT
cord-008530-yni0poh9	238	20	CNS	CNS	NNP
cord-008530-yni0poh9	238	21	,	,	,
cord-008530-yni0poh9	238	22	such	such	JJ
cord-008530-yni0poh9	238	23	as	as	IN
cord-008530-yni0poh9	238	24	multiple	multiple	JJ
cord-008530-yni0poh9	238	25	sclerosis	sclerosis	NN
cord-008530-yni0poh9	238	26	(	(	-LRB-
cord-008530-yni0poh9	238	27	MS	MS	NNP
cord-008530-yni0poh9	238	28	)	)	-RRB-
cord-008530-yni0poh9	238	29	.	.	.
cord-008530-yni0poh9	239	1	As	as	IN
cord-008530-yni0poh9	239	2	a	a	DT
cord-008530-yni0poh9	239	3	result	result	NN
cord-008530-yni0poh9	239	4	,	,	,
cord-008530-yni0poh9	239	5	it	-PRON-	PRP
cord-008530-yni0poh9	239	6	has	have	VBZ
cord-008530-yni0poh9	239	7	become	become	VBN
cord-008530-yni0poh9	239	8	clear	clear	JJ
cord-008530-yni0poh9	239	9	that	that	IN
cord-008530-yni0poh9	239	10	most	most	JJS
cord-008530-yni0poh9	239	11	cells	cell	NNS
cord-008530-yni0poh9	239	12	resident	resident	JJ
cord-008530-yni0poh9	239	13	in	in	IN
cord-008530-yni0poh9	239	14	the	the	DT
cord-008530-yni0poh9	239	15	CNS	CNS	NNP
cord-008530-yni0poh9	239	16	,	,	,
cord-008530-yni0poh9	239	17	including	include	VBG
cord-008530-yni0poh9	239	18	neurons	neuron	NNS
cord-008530-yni0poh9	239	19	,	,	,
cord-008530-yni0poh9	239	20	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	239	21	,	,	,
cord-008530-yni0poh9	239	22	and	and	CC
cord-008530-yni0poh9	239	23	microglia	microglia	NN
cord-008530-yni0poh9	239	24	,	,	,
cord-008530-yni0poh9	239	25	can	can	MD
cord-008530-yni0poh9	239	26	synthesize	synthesize	VB
cord-008530-yni0poh9	239	27	and	and	CC
cord-008530-yni0poh9	239	28	secrete	secrete	VB
cord-008530-yni0poh9	239	29	various	various	JJ
cord-008530-yni0poh9	239	30	classes	class	NNS
cord-008530-yni0poh9	239	31	of	of	IN
cord-008530-yni0poh9	239	32	chemokines	chemokine	NNS
cord-008530-yni0poh9	239	33	.	.	.
cord-008530-yni0poh9	240	1	Importantly	importantly	RB
cord-008530-yni0poh9	240	2	,	,	,
cord-008530-yni0poh9	240	3	these	these	DT
cord-008530-yni0poh9	240	4	same	same	JJ
cord-008530-yni0poh9	240	5	cells	cell	NNS
cord-008530-yni0poh9	240	6	are	be	VBP
cord-008530-yni0poh9	240	7	endowed	endow	VBN
cord-008530-yni0poh9	240	8	with	with	IN
cord-008530-yni0poh9	240	9	a	a	DT
cord-008530-yni0poh9	240	10	variety	variety	NN
cord-008530-yni0poh9	240	11	of	of	IN
cord-008530-yni0poh9	240	12	different	different	JJ
cord-008530-yni0poh9	240	13	chemokine	chemokine	NN
cord-008530-yni0poh9	240	14	receptors	receptor	NNS
cord-008530-yni0poh9	240	15	and	and	CC
cord-008530-yni0poh9	240	16	therefore	therefore	RB
cord-008530-yni0poh9	240	17	have	have	VBP
cord-008530-yni0poh9	240	18	the	the	DT
cord-008530-yni0poh9	240	19	potential	potential	NN
cord-008530-yni0poh9	240	20	to	to	TO
cord-008530-yni0poh9	240	21	respond	respond	VB
cord-008530-yni0poh9	240	22	to	to	IN
cord-008530-yni0poh9	240	23	chemokines	chemokine	NNS
cord-008530-yni0poh9	240	24	in	in	IN
cord-008530-yni0poh9	240	25	their	-PRON-	PRP$
cord-008530-yni0poh9	240	26	local	local	JJ
cord-008530-yni0poh9	240	27	environment	environment	NN
cord-008530-yni0poh9	240	28	.	.	.
cord-008530-yni0poh9	241	1	As	as	IN
cord-008530-yni0poh9	241	2	recently	recently	RB
cord-008530-yni0poh9	241	3	speculated	speculate	VBN
cord-008530-yni0poh9	241	4	by	by	IN
cord-008530-yni0poh9	241	5	us	-PRON-	PRP
cord-008530-yni0poh9	241	6	(	(	-LRB-
cord-008530-yni0poh9	241	7	Asensio	Asensio	NNP
cord-008530-yni0poh9	241	8	and	and	CC
cord-008530-yni0poh9	241	9	Campbell	Campbell	NNP
cord-008530-yni0poh9	241	10	,	,	,
cord-008530-yni0poh9	241	11	1999	1999	CD
cord-008530-yni0poh9	241	12	)	)	-RRB-
cord-008530-yni0poh9	241	13	and	and	CC
cord-008530-yni0poh9	241	14	by	by	IN
cord-008530-yni0poh9	241	15	others	other	NNS
cord-008530-yni0poh9	241	16	(	(	-LRB-
cord-008530-yni0poh9	241	17	Mennicken	Mennicken	NNP
cord-008530-yni0poh9	241	18	et	et	FW
cord-008530-yni0poh9	241	19	al	al	NNP
cord-008530-yni0poh9	241	20	.	.	NNP
cord-008530-yni0poh9	241	21	,	,	,
cord-008530-yni0poh9	241	22	1999	1999	CD
cord-008530-yni0poh9	241	23	)	)	-RRB-
cord-008530-yni0poh9	241	24	,	,	,
cord-008530-yni0poh9	241	25	it	-PRON-	PRP
cord-008530-yni0poh9	241	26	is	be	VBZ
cord-008530-yni0poh9	241	27	likely	likely	RB
cord-008530-yni0poh9	241	28	the	the	DT
cord-008530-yni0poh9	241	29	CNS	CNS	NNP
cord-008530-yni0poh9	241	30	has	have	VBZ
cord-008530-yni0poh9	241	31	its	-PRON-	PRP$
cord-008530-yni0poh9	241	32	own	own	JJ
cord-008530-yni0poh9	241	33	chemokine	chemokine	NN
cord-008530-yni0poh9	241	34	ligand	ligand	NN
cord-008530-yni0poh9	241	35	/	/	SYM
cord-008530-yni0poh9	241	36	receptor	receptor	NN
cord-008530-yni0poh9	241	37	network	network	NN
cord-008530-yni0poh9	241	38	,	,	,
cord-008530-yni0poh9	241	39	the	the	DT
cord-008530-yni0poh9	241	40	function	function	NN
cord-008530-yni0poh9	241	41	of	of	IN
cord-008530-yni0poh9	241	42	which	which	WDT
cord-008530-yni0poh9	241	43	could	could	MD
cord-008530-yni0poh9	241	44	extend	extend	VB
cord-008530-yni0poh9	241	45	well	well	RB
cord-008530-yni0poh9	241	46	beyond	beyond	IN
cord-008530-yni0poh9	241	47	the	the	DT
cord-008530-yni0poh9	241	48	regulation	regulation	NN
cord-008530-yni0poh9	241	49	of	of	IN
cord-008530-yni0poh9	241	50	leukocyte	leukocyte	NN
cord-008530-yni0poh9	241	51	trafficking	trafficking	NN
cord-008530-yni0poh9	241	52	in	in	IN
cord-008530-yni0poh9	241	53	antiviral	antiviral	JJ
cord-008530-yni0poh9	241	54	and	and	CC
cord-008530-yni0poh9	241	55	other	other	JJ
cord-008530-yni0poh9	241	56	neuroimmune	neuroimmune	NNP
cord-008530-yni0poh9	241	57	responses	response	NNS
cord-008530-yni0poh9	241	58	(	(	-LRB-
cord-008530-yni0poh9	241	59	see	see	VB
cord-008530-yni0poh9	241	60	Fig	Fig	NNP
cord-008530-yni0poh9	241	61	.	.	.
cord-008530-yni0poh9	241	62	3	3	CD
cord-008530-yni0poh9	241	63	)	)	-RRB-
cord-008530-yni0poh9	241	64	.	.	.
cord-008530-yni0poh9	242	1	At	at	IN
cord-008530-yni0poh9	242	2	present	present	NN
cord-008530-yni0poh9	242	3	,	,	,
cord-008530-yni0poh9	242	4	the	the	DT
cord-008530-yni0poh9	242	5	genes	gene	NNS
cord-008530-yni0poh9	242	6	for	for	IN
cord-008530-yni0poh9	242	7	only	only	RB
cord-008530-yni0poh9	242	8	three	three	CD
cord-008530-yni0poh9	242	9	chemokines	chemokine	NNS
cord-008530-yni0poh9	242	10	,	,	,
cord-008530-yni0poh9	242	11	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	242	12	,	,	,
cord-008530-yni0poh9	242	13	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	242	14	,	,	,
cord-008530-yni0poh9	242	15	and	and	CC
cord-008530-yni0poh9	242	16	fractalkine	fractalkine	NN
cord-008530-yni0poh9	242	17	,	,	,
cord-008530-yni0poh9	242	18	are	be	VBP
cord-008530-yni0poh9	242	19	known	know	VBN
cord-008530-yni0poh9	242	20	to	to	TO
cord-008530-yni0poh9	242	21	be	be	VB
cord-008530-yni0poh9	242	22	expressed	express	VBN
cord-008530-yni0poh9	242	23	constitutively	constitutively	RB
cord-008530-yni0poh9	242	24	in	in	IN
cord-008530-yni0poh9	242	25	the	the	DT
cord-008530-yni0poh9	242	26	CNS	CNS	NNP
cord-008530-yni0poh9	242	27	.	.	.
cord-008530-yni0poh9	243	1	Evidence	evidence	NN
cord-008530-yni0poh9	243	2	suggests	suggest	VBZ
cord-008530-yni0poh9	243	3	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	243	4	is	be	VBZ
cord-008530-yni0poh9	243	5	expressed	express	VBN
cord-008530-yni0poh9	243	6	in	in	IN
cord-008530-yni0poh9	243	7	the	the	DT
cord-008530-yni0poh9	243	8	cortex	cortex	NN
cord-008530-yni0poh9	243	9	and	and	CC
cord-008530-yni0poh9	243	10	hippocampus	hippocampus	NN
cord-008530-yni0poh9	243	11	of	of	IN
cord-008530-yni0poh9	243	12	the	the	DT
cord-008530-yni0poh9	243	13	rat	rat	NN
cord-008530-yni0poh9	243	14	brain	brain	NN
cord-008530-yni0poh9	243	15	during	during	IN
cord-008530-yni0poh9	243	16	development	development	NN
cord-008530-yni0poh9	243	17	as	as	RB
cord-008530-yni0poh9	243	18	well	well	RB
cord-008530-yni0poh9	243	19	as	as	IN
cord-008530-yni0poh9	243	20	in	in	IN
cord-008530-yni0poh9	243	21	the	the	DT
cord-008530-yni0poh9	243	22	adult	adult	NN
cord-008530-yni0poh9	243	23	animal	animal	NN
cord-008530-yni0poh9	243	24	(	(	-LRB-
cord-008530-yni0poh9	243	25	Pousset	Pousset	NNP
cord-008530-yni0poh9	243	26	,	,	,
cord-008530-yni0poh9	243	27	1994	1994	CD
cord-008530-yni0poh9	243	28	)	)	-RRB-
cord-008530-yni0poh9	243	29	.	.	.
cord-008530-yni0poh9	244	1	More	more	RBR
cord-008530-yni0poh9	244	2	recently	recently	RB
cord-008530-yni0poh9	244	3	,	,	,
cord-008530-yni0poh9	244	4	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	244	5	expression	expression	NN
cord-008530-yni0poh9	244	6	at	at	IN
cord-008530-yni0poh9	244	7	the	the	DT
cord-008530-yni0poh9	244	8	protein	protein	NN
cord-008530-yni0poh9	244	9	level	level	NN
cord-008530-yni0poh9	244	10	was	be	VBD
cord-008530-yni0poh9	244	11	shown	show	VBN
cord-008530-yni0poh9	244	12	in	in	IN
cord-008530-yni0poh9	244	13	the	the	DT
cord-008530-yni0poh9	244	14	human	human	JJ
cord-008530-yni0poh9	244	15	cerebellum	cerebellum	NN
cord-008530-yni0poh9	244	16	,	,	,
cord-008530-yni0poh9	244	17	medulla	medulla	NNP
cord-008530-yni0poh9	244	18	oblongata	oblongata	NNP
cord-008530-yni0poh9	244	19	,	,	,
cord-008530-yni0poh9	244	20	and	and	CC
cord-008530-yni0poh9	244	21	pons	pons	NNP
cord-008530-yni0poh9	244	22	(	(	-LRB-
cord-008530-yni0poh9	244	23	Meng	Meng	NNP
cord-008530-yni0poh9	244	24	et	et	FW
cord-008530-yni0poh9	244	25	al	al	NNP
cord-008530-yni0poh9	244	26	.	.	NNP
cord-008530-yni0poh9	244	27	,	,	,
cord-008530-yni0poh9	244	28	1999	1999	CD
cord-008530-yni0poh9	244	29	)	)	-RRB-
cord-008530-yni0poh9	244	30	.	.	.
cord-008530-yni0poh9	245	1	However	however	RB
cord-008530-yni0poh9	245	2	,	,	,
cord-008530-yni0poh9	245	3	the	the	DT
cord-008530-yni0poh9	245	4	function	function	NN
cord-008530-yni0poh9	245	5	of	of	IN
cord-008530-yni0poh9	245	6	constitutively	constitutively	RB
cord-008530-yni0poh9	245	7	expressed	express	VBN
cord-008530-yni0poh9	245	8	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	245	9	in	in	IN
cord-008530-yni0poh9	245	10	the	the	DT
cord-008530-yni0poh9	245	11	brain	brain	NN
cord-008530-yni0poh9	245	12	is	be	VBZ
cord-008530-yni0poh9	245	13	unknown	unknown	JJ
cord-008530-yni0poh9	245	14	.	.	.
cord-008530-yni0poh9	246	1	The	the	DT
cord-008530-yni0poh9	246	2	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	246	3	gene	gene	NN
cord-008530-yni0poh9	246	4	is	be	VBZ
cord-008530-yni0poh9	246	5	found	find	VBN
cord-008530-yni0poh9	246	6	under	under	IN
cord-008530-yni0poh9	246	7	physiological	physiological	JJ
cord-008530-yni0poh9	246	8	conditions	condition	NNS
cord-008530-yni0poh9	246	9	in	in	IN
cord-008530-yni0poh9	246	10	many	many	JJ
cord-008530-yni0poh9	246	11	organs	organ	NNS
cord-008530-yni0poh9	246	12	including	include	VBG
cord-008530-yni0poh9	246	13	murine	murine	JJ
cord-008530-yni0poh9	246	14	(	(	-LRB-
cord-008530-yni0poh9	246	15	Tashiro	Tashiro	NNP
cord-008530-yni0poh9	246	16	et	et	FW
cord-008530-yni0poh9	246	17	al	al	NNP
cord-008530-yni0poh9	246	18	.	.	NNP
cord-008530-yni0poh9	246	19	,	,	,
cord-008530-yni0poh9	246	20	1993	1993	CD
cord-008530-yni0poh9	246	21	)	)	-RRB-
cord-008530-yni0poh9	246	22	and	and	CC
cord-008530-yni0poh9	246	23	human	human	JJ
cord-008530-yni0poh9	246	24	(	(	-LRB-
cord-008530-yni0poh9	246	25	Shirozu	Shirozu	NNP
cord-008530-yni0poh9	246	26	et	et	FW
cord-008530-yni0poh9	246	27	al	al	NNP
cord-008530-yni0poh9	246	28	.	.	NNP
cord-008530-yni0poh9	246	29	,	,	,
cord-008530-yni0poh9	246	30	1995	1995	CD
cord-008530-yni0poh9	246	31	)	)	-RRB-
cord-008530-yni0poh9	246	32	brain	brain	NN
cord-008530-yni0poh9	246	33	.	.	.
cord-008530-yni0poh9	247	1	SDF-1	sdf-1	NN
cord-008530-yni0poh9	247	2	has	have	VBZ
cord-008530-yni0poh9	247	3	two	two	CD
cord-008530-yni0poh9	247	4	isoforms	isoform	NNS
cord-008530-yni0poh9	247	5	,	,	,
cord-008530-yni0poh9	247	6	SDF	SDF	NNP
cord-008530-yni0poh9	247	7	-	-	HYPH
cord-008530-yni0poh9	247	8	la	la	NNP
cord-008530-yni0poh9	247	9	and	and	CC
cord-008530-yni0poh9	247	10	SDF	SDF	NNP
cord-008530-yni0poh9	247	11	-	-	HYPH
cord-008530-yni0poh9	247	12	I~	I~	NNP
cord-008530-yni0poh9	247	13	,	,	,
cord-008530-yni0poh9	247	14	that	that	WDT
cord-008530-yni0poh9	247	15	are	be	VBP
cord-008530-yni0poh9	247	16	produced	produce	VBN
cord-008530-yni0poh9	247	17	by	by	IN
cord-008530-yni0poh9	247	18	alternative	alternative	JJ
cord-008530-yni0poh9	247	19	splicing	splicing	NN
cord-008530-yni0poh9	247	20	from	from	IN
cord-008530-yni0poh9	247	21	a	a	DT
cord-008530-yni0poh9	247	22	single	single	JJ
cord-008530-yni0poh9	247	23	gene	gene	NN
cord-008530-yni0poh9	247	24	(	(	-LRB-
cord-008530-yni0poh9	247	25	Tashiro	Tashiro	NNP
cord-008530-yni0poh9	247	26	et	et	FW
cord-008530-yni0poh9	247	27	al	al	NNP
cord-008530-yni0poh9	247	28	.	.	NNP
cord-008530-yni0poh9	247	29	,	,	,
cord-008530-yni0poh9	247	30	1993	1993	CD
cord-008530-yni0poh9	247	31	)	)	-RRB-
cord-008530-yni0poh9	247	32	.	.	.
cord-008530-yni0poh9	248	1	SDF	SDF	NNP
cord-008530-yni0poh9	248	2	-	-	HYPH
cord-008530-yni0poh9	248	3	la	la	NNP
cord-008530-yni0poh9	248	4	RNA	RNA	NNP
cord-008530-yni0poh9	248	5	is	be	VBZ
cord-008530-yni0poh9	248	6	present	present	JJ
cord-008530-yni0poh9	248	7	at	at	IN
cord-008530-yni0poh9	248	8	high	high	JJ
cord-008530-yni0poh9	248	9	levels	level	NNS
cord-008530-yni0poh9	248	10	in	in	IN
cord-008530-yni0poh9	248	11	cultured	cultured	JJ
cord-008530-yni0poh9	248	12	rat	rat	NN
cord-008530-yni0poh9	248	13	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	248	14	,	,	,
cord-008530-yni0poh9	248	15	at	at	IN
cord-008530-yni0poh9	248	16	low	low	JJ
cord-008530-yni0poh9	248	17	levels	level	NNS
cord-008530-yni0poh9	248	18	in	in	IN
cord-008530-yni0poh9	248	19	neurons	neuron	NNS
cord-008530-yni0poh9	248	20	,	,	,
cord-008530-yni0poh9	248	21	and	and	CC
cord-008530-yni0poh9	248	22	is	be	VBZ
cord-008530-yni0poh9	248	23	not	not	RB
cord-008530-yni0poh9	248	24	detectable	detectable	JJ
cord-008530-yni0poh9	248	25	in	in	IN
cord-008530-yni0poh9	248	26	microglia	microglia	NN
cord-008530-yni0poh9	248	27	,	,	,
cord-008530-yni0poh9	248	28	while	while	IN
cord-008530-yni0poh9	248	29	SDF-1~	SDF-1~	NNS
cord-008530-yni0poh9	248	30	RNAis	RNAis	NNP
cord-008530-yni0poh9	248	31	found	find	VBN
cord-008530-yni0poh9	248	32	at	at	IN
cord-008530-yni0poh9	248	33	low	low	JJ
cord-008530-yni0poh9	248	34	levels	level	NNS
cord-008530-yni0poh9	248	35	in	in	IN
cord-008530-yni0poh9	248	36	all	all	PDT
cord-008530-yni0poh9	248	37	these	these	DT
cord-008530-yni0poh9	248	38	cell	cell	NN
cord-008530-yni0poh9	248	39	types	type	NNS
cord-008530-yni0poh9	248	40	.	.	.
cord-008530-yni0poh9	249	1	Tanabe	Tanabe	NNP
cord-008530-yni0poh9	249	2	et	et	NNP
cord-008530-yni0poh9	249	3	al	al	NNP
cord-008530-yni0poh9	249	4	.	.	.
cord-008530-yni0poh9	250	1	(	(	-LRB-
cord-008530-yni0poh9	250	2	1997b	1997b	CD
cord-008530-yni0poh9	250	3	)	)	-RRB-
cord-008530-yni0poh9	250	4	showed	show	VBD
cord-008530-yni0poh9	250	5	that	that	IN
cord-008530-yni0poh9	250	6	SDF	SDF	NNP
cord-008530-yni0poh9	250	7	-	-	HYPH
cord-008530-yni0poh9	250	8	la	la	NNP
cord-008530-yni0poh9	250	9	was	be	VBD
cord-008530-yni0poh9	250	10	able	able	JJ
cord-008530-yni0poh9	250	11	to	to	TO
cord-008530-yni0poh9	250	12	induce	induce	VB
cord-008530-yni0poh9	250	13	migration	migration	NN
cord-008530-yni0poh9	250	14	of	of	IN
cord-008530-yni0poh9	250	15	microglial	microglial	JJ
cord-008530-yni0poh9	250	16	cells	cell	NNS
cord-008530-yni0poh9	250	17	but	but	CC
cord-008530-yni0poh9	250	18	not	not	RB
cord-008530-yni0poh9	250	19	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	250	20	,	,	,
cord-008530-yni0poh9	250	21	even	even	RB
cord-008530-yni0poh9	250	22	though	though	IN
cord-008530-yni0poh9	250	23	the	the	DT
cord-008530-yni0poh9	250	24	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	250	25	receptor	receptor	NN
cord-008530-yni0poh9	250	26	,	,	,
cord-008530-yni0poh9	250	27	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	250	28	,	,	,
cord-008530-yni0poh9	250	29	was	be	VBD
cord-008530-yni0poh9	250	30	expressed	express	VBN
cord-008530-yni0poh9	250	31	on	on	IN
cord-008530-yni0poh9	250	32	both	both	DT
cord-008530-yni0poh9	250	33	cell	cell	NN
cord-008530-yni0poh9	250	34	types	type	NNS
cord-008530-yni0poh9	250	35	.	.	.
cord-008530-yni0poh9	251	1	Furthermore	furthermore	RB
cord-008530-yni0poh9	251	2	,	,	,
cord-008530-yni0poh9	251	3	human	human	JJ
cord-008530-yni0poh9	251	4	SDFla	SDFla	NNP
cord-008530-yni0poh9	251	5	was	be	VBD
cord-008530-yni0poh9	251	6	able	able	JJ
cord-008530-yni0poh9	251	7	to	to	TO
cord-008530-yni0poh9	251	8	induce	induce	VB
cord-008530-yni0poh9	251	9	calcium	calcium	NN
cord-008530-yni0poh9	251	10	flux	flux	NN
cord-008530-yni0poh9	251	11	in	in	IN
cord-008530-yni0poh9	251	12	cultured	cultured	JJ
cord-008530-yni0poh9	251	13	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	252	1	(	(	-LRB-
cord-008530-yni0poh9	252	2	Bajetto	Bajetto	NNP
cord-008530-yni0poh9	252	3	et	et	NNP
cord-008530-yni0poh9	252	4	al	al	NNP
cord-008530-yni0poh9	252	5	.	.	NNP
cord-008530-yni0poh9	252	6	,	,	,
cord-008530-yni0poh9	252	7	1999	1999	CD
cord-008530-yni0poh9	252	8	)	)	-RRB-
cord-008530-yni0poh9	252	9	.	.	.
cord-008530-yni0poh9	253	1	It	-PRON-	PRP
cord-008530-yni0poh9	253	2	was	be	VBD
cord-008530-yni0poh9	253	3	hypothesized	hypothesize	VBN
cord-008530-yni0poh9	253	4	that	that	IN
cord-008530-yni0poh9	253	5	astrocyte	astrocyte	NN
cord-008530-yni0poh9	253	6	-	-	HYPH
cord-008530-yni0poh9	253	7	secreted	secrete	VBN
cord-008530-yni0poh9	253	8	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	253	9	could	could	MD
cord-008530-yni0poh9	253	10	facilitate	facilitate	VB
cord-008530-yni0poh9	253	11	interneural	interneural	JJ
cord-008530-yni0poh9	253	12	cell	cell	NN
cord-008530-yni0poh9	253	13	communication	communication	NN
cord-008530-yni0poh9	253	14	.	.	.
cord-008530-yni0poh9	254	1	This	this	DT
cord-008530-yni0poh9	254	2	is	be	VBZ
cord-008530-yni0poh9	254	3	certainly	certainly	RB
cord-008530-yni0poh9	254	4	the	the	DT
cord-008530-yni0poh9	254	5	case	case	NN
cord-008530-yni0poh9	254	6	during	during	IN
cord-008530-yni0poh9	254	7	CNS	CNS	NNP
cord-008530-yni0poh9	254	8	development	development	NN
cord-008530-yni0poh9	254	9	,	,	,
cord-008530-yni0poh9	254	10	since	since	IN
cord-008530-yni0poh9	254	11	,	,	,
cord-008530-yni0poh9	254	12	as	as	IN
cord-008530-yni0poh9	254	13	noted	note	VBN
cord-008530-yni0poh9	254	14	above	above	RB
cord-008530-yni0poh9	254	15	,	,	,
cord-008530-yni0poh9	254	16	knocking	knock	VBG
cord-008530-yni0poh9	254	17	out	out	RP
cord-008530-yni0poh9	254	18	CXCR4	cxcr4	NN
cord-008530-yni0poh9	254	19	results	result	NNS
cord-008530-yni0poh9	254	20	in	in	IN
cord-008530-yni0poh9	254	21	a	a	DT
cord-008530-yni0poh9	254	22	major	major	JJ
cord-008530-yni0poh9	254	23	defect	defect	NN
cord-008530-yni0poh9	254	24	in	in	IN
cord-008530-yni0poh9	254	25	granule	granule	NN
cord-008530-yni0poh9	254	26	cell	cell	NN
cord-008530-yni0poh9	254	27	migration	migration	NN
cord-008530-yni0poh9	254	28	and	and	CC
cord-008530-yni0poh9	254	29	cerebellar	cerebellar	JJ
cord-008530-yni0poh9	254	30	development	development	NN
cord-008530-yni0poh9	254	31	Zou	Zou	NNP
cord-008530-yni0poh9	254	32	et	et	FW
cord-008530-yni0poh9	254	33	al	al	NNP
cord-008530-yni0poh9	254	34	.	.	NNP
cord-008530-yni0poh9	254	35	,	,	,
cord-008530-yni0poh9	254	36	1998	1998	CD
cord-008530-yni0poh9	254	37	)	)	-RRB-
cord-008530-yni0poh9	254	38	.	.	.
cord-008530-yni0poh9	255	1	The	the	DT
cord-008530-yni0poh9	255	2	CX3C	CX3C	NNS
cord-008530-yni0poh9	255	3	chemokine	chemokine	NN
cord-008530-yni0poh9	255	4	fractalkine	fractalkine	NN
cord-008530-yni0poh9	255	5	is	be	VBZ
cord-008530-yni0poh9	255	6	also	also	RB
cord-008530-yni0poh9	255	7	found	find	VBN
cord-008530-yni0poh9	255	8	constitutively	constitutively	RB
cord-008530-yni0poh9	255	9	in	in	IN
cord-008530-yni0poh9	255	10	the	the	DT
cord-008530-yni0poh9	255	11	brain	brain	NN
cord-008530-yni0poh9	255	12	(	(	-LRB-
cord-008530-yni0poh9	255	13	Bazan	Bazan	NNP
cord-008530-yni0poh9	255	14	et	et	NNP
cord-008530-yni0poh9	255	15	al	al	NNP
cord-008530-yni0poh9	255	16	.	.	NNP
cord-008530-yni0poh9	255	17	,	,	,
cord-008530-yni0poh9	255	18	1997	1997	CD
cord-008530-yni0poh9	255	19	;	;	:
cord-008530-yni0poh9	255	20	Pan	Pan	NNP
cord-008530-yni0poh9	255	21	et	et	NNP
cord-008530-yni0poh9	255	22	al	al	NNP
cord-008530-yni0poh9	255	23	.	.	NNP
cord-008530-yni0poh9	255	24	,	,	,
cord-008530-yni0poh9	255	25	1997	1997	CD
cord-008530-yni0poh9	255	26	)	)	-RRB-
cord-008530-yni0poh9	255	27	.	.	.
cord-008530-yni0poh9	256	1	Fractalkine	Fractalkine	NNP
cord-008530-yni0poh9	256	2	mRNA	mRNA	NNP
cord-008530-yni0poh9	256	3	is	be	VBZ
cord-008530-yni0poh9	256	4	expressed	express	VBN
cord-008530-yni0poh9	256	5	at	at	IN
cord-008530-yni0poh9	256	6	high	high	JJ
cord-008530-yni0poh9	256	7	levels	level	NNS
cord-008530-yni0poh9	256	8	by	by	IN
cord-008530-yni0poh9	256	9	neurons	neuron	NNS
cord-008530-yni0poh9	256	10	in	in	IN
cord-008530-yni0poh9	256	11	the	the	DT
cord-008530-yni0poh9	256	12	olfactory	olfactory	JJ
cord-008530-yni0poh9	256	13	bulb	bulb	NN
cord-008530-yni0poh9	256	14	,	,	,
cord-008530-yni0poh9	256	15	cerebral	cerebral	JJ
cord-008530-yni0poh9	256	16	cortex	cortex	NNP
cord-008530-yni0poh9	256	17	hippocampus	hippocampus	NNP
cord-008530-yni0poh9	256	18	,	,	,
cord-008530-yni0poh9	256	19	caudate	caudate	NNP
cord-008530-yni0poh9	256	20	putamen	putamen	NNP
cord-008530-yni0poh9	256	21	,	,	,
cord-008530-yni0poh9	256	22	and	and	CC
cord-008530-yni0poh9	256	23	nucleus	nucleus	NN
cord-008530-yni0poh9	256	24	accumbens	accumbens	NNP
cord-008530-yni0poh9	256	25	Nishiyori	Nishiyori	NNP
cord-008530-yni0poh9	256	26	et	et	NNP
cord-008530-yni0poh9	256	27	al	al	NNP
cord-008530-yni0poh9	256	28	.	.	NNP
cord-008530-yni0poh9	256	29	,	,	,
cord-008530-yni0poh9	256	30	1998	1998	CD
cord-008530-yni0poh9	256	31	;	;	:
cord-008530-yni0poh9	256	32	Schwaeble	Schwaeble	NNP
cord-008530-yni0poh9	256	33	et	et	FW
cord-008530-yni0poh9	256	34	al	al	NNP
cord-008530-yni0poh9	256	35	.	.	NNP
cord-008530-yni0poh9	256	36	,	,	,
cord-008530-yni0poh9	256	37	1998	1998	CD
cord-008530-yni0poh9	256	38	)	)	-RRB-
cord-008530-yni0poh9	256	39	.	.	.
cord-008530-yni0poh9	257	1	In	in	IN
cord-008530-yni0poh9	257	2	vitro	vitro	FW
cord-008530-yni0poh9	257	3	studies	study	NNS
cord-008530-yni0poh9	257	4	have	have	VBP
cord-008530-yni0poh9	257	5	confirmed	confirm	VBN
cord-008530-yni0poh9	257	6	that	that	IN
cord-008530-yni0poh9	257	7	fractalkine	fractalkine	NN
cord-008530-yni0poh9	257	8	is	be	VBZ
cord-008530-yni0poh9	257	9	constitutively	constitutively	RB
cord-008530-yni0poh9	257	10	expressed	express	VBN
cord-008530-yni0poh9	257	11	by	by	IN
cord-008530-yni0poh9	257	12	neurons	neuron	NNS
cord-008530-yni0poh9	257	13	and	and	CC
cord-008530-yni0poh9	257	14	,	,	,
cord-008530-yni0poh9	257	15	further	further	RB
cord-008530-yni0poh9	257	16	,	,	,
cord-008530-yni0poh9	257	17	can	can	MD
cord-008530-yni0poh9	257	18	be	be	VB
cord-008530-yni0poh9	257	19	induced	induce	VBN
cord-008530-yni0poh9	257	20	in	in	IN
cord-008530-yni0poh9	257	21	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	257	22	by	by	IN
cord-008530-yni0poh9	257	23	TNF	TNF	NNP
cord-008530-yni0poh9	257	24	-	-	:
cord-008530-yni0poh9	257	25	a	a	NNP
cord-008530-yni0poh9	257	26	and	and	CC
cord-008530-yni0poh9	257	27	IL	IL	NNP
cord-008530-yni0poh9	257	28	-	-	HYPH
cord-008530-yni0poh9	257	29	I~	I~	NNP
cord-008530-yni0poh9	257	30	(	(	-LRB-
cord-008530-yni0poh9	257	31	Maciejewski	Maciejewski	NNP
cord-008530-yni0poh9	257	32	-	-	HYPH
cord-008530-yni0poh9	257	33	Lenoir	Lenoir	NNP
cord-008530-yni0poh9	257	34	et	et	NNP
cord-008530-yni0poh9	257	35	al	al	NNP
cord-008530-yni0poh9	257	36	.	.	NNP
cord-008530-yni0poh9	257	37	,	,	,
cord-008530-yni0poh9	257	38	1999	1999	CD
cord-008530-yni0poh9	257	39	)	)	-RRB-
cord-008530-yni0poh9	257	40	.	.	.
cord-008530-yni0poh9	258	1	In	in	IN
cord-008530-yni0poh9	258	2	a	a	DT
cord-008530-yni0poh9	258	3	model	model	NN
cord-008530-yni0poh9	258	4	of	of	IN
cord-008530-yni0poh9	258	5	peripheral	peripheral	JJ
cord-008530-yni0poh9	258	6	nerve	nerve	NN
cord-008530-yni0poh9	258	7	injury	injury	NN
cord-008530-yni0poh9	258	8	,	,	,
cord-008530-yni0poh9	258	9	Harrison	Harrison	NNP
cord-008530-yni0poh9	258	10	et	et	NNP
cord-008530-yni0poh9	258	11	al	al	NNP
cord-008530-yni0poh9	258	12	.	.	NNP
cord-008530-yni0poh9	258	13	have	have	VBP
cord-008530-yni0poh9	258	14	shown	show	VBN
cord-008530-yni0poh9	258	15	that	that	IN
cord-008530-yni0poh9	258	16	fractalkine	fractalkine	NN
cord-008530-yni0poh9	258	17	and	and	CC
cord-008530-yni0poh9	258	18	its	-PRON-	PRP$
cord-008530-yni0poh9	258	19	receptor	receptor	NN
cord-008530-yni0poh9	258	20	were	be	VBD
cord-008530-yni0poh9	258	21	highly	highly	RB
cord-008530-yni0poh9	258	22	upregulated	upregulate	VBN
cord-008530-yni0poh9	258	23	in	in	IN
cord-008530-yni0poh9	258	24	the	the	DT
cord-008530-yni0poh9	258	25	brain	brain	NN
cord-008530-yni0poh9	258	26	,	,	,
cord-008530-yni0poh9	258	27	with	with	IN
cord-008530-yni0poh9	258	28	motor	motor	NN
cord-008530-yni0poh9	258	29	neurons	neuron	NNS
cord-008530-yni0poh9	258	30	being	be	VBG
cord-008530-yni0poh9	258	31	the	the	DT
cord-008530-yni0poh9	258	32	primary	primary	JJ
cord-008530-yni0poh9	258	33	source	source	NN
cord-008530-yni0poh9	258	34	of	of	IN
cord-008530-yni0poh9	258	35	the	the	DT
cord-008530-yni0poh9	258	36	chemokine	chemokine	NN
cord-008530-yni0poh9	258	37	.	.	.
cord-008530-yni0poh9	259	1	Fractalkine	fractalkine	JJ
cord-008530-yni0poh9	259	2	treatment	treatment	NN
cord-008530-yni0poh9	259	3	of	of	IN
cord-008530-yni0poh9	259	4	primary	primary	JJ
cord-008530-yni0poh9	259	5	cultured	cultured	JJ
cord-008530-yni0poh9	259	6	rat	rat	NN
cord-008530-yni0poh9	259	7	microglial	microglial	JJ
cord-008530-yni0poh9	259	8	cells	cell	NNS
cord-008530-yni0poh9	259	9	induces	induce	VBZ
cord-008530-yni0poh9	259	10	vigorous	vigorous	JJ
cord-008530-yni0poh9	259	11	increases	increase	NNS
cord-008530-yni0poh9	259	12	in	in	IN
cord-008530-yni0poh9	259	13	intracellular	intracellular	JJ
cord-008530-yni0poh9	259	14	Ca	Ca	NNP
cord-008530-yni0poh9	259	15	2	2	CD
cord-008530-yni0poh9	259	16	+	+	SYM
cord-008530-yni0poh9	259	17	levels	level	NNS
cord-008530-yni0poh9	259	18	and	and	CC
cord-008530-yni0poh9	259	19	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	259	20	,	,	,
cord-008530-yni0poh9	259	21	which	which	WDT
cord-008530-yni0poh9	259	22	are	be	VBP
cord-008530-yni0poh9	259	23	inhibited	inhibit	VBN
cord-008530-yni0poh9	259	24	by	by	IN
cord-008530-yni0poh9	259	25	an	an	DT
cord-008530-yni0poh9	259	26	antibody	antibody	NN
cord-008530-yni0poh9	259	27	against	against	IN
cord-008530-yni0poh9	259	28	the	the	DT
cord-008530-yni0poh9	259	29	fractalkine	fractalkine	NN
cord-008530-yni0poh9	259	30	(	(	-LRB-
cord-008530-yni0poh9	259	31	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	259	32	)	)	-RRB-
cord-008530-yni0poh9	259	33	receptor	receptor	NN
cord-008530-yni0poh9	259	34	.	.	.
cord-008530-yni0poh9	260	1	Although	although	IN
cord-008530-yni0poh9	260	2	the	the	DT
cord-008530-yni0poh9	260	3	precise	precise	JJ
cord-008530-yni0poh9	260	4	function	function	NN
cord-008530-yni0poh9	260	5	of	of	IN
cord-008530-yni0poh9	260	6	fractalkine	fractalkine	NN
cord-008530-yni0poh9	260	7	in	in	IN
cord-008530-yni0poh9	260	8	the	the	DT
cord-008530-yni0poh9	260	9	CNS	CNS	NNP
cord-008530-yni0poh9	260	10	awaits	await	VBZ
cord-008530-yni0poh9	260	11	clarification	clarification	NN
cord-008530-yni0poh9	260	12	,	,	,
cord-008530-yni0poh9	260	13	the	the	DT
cord-008530-yni0poh9	260	14	localization	localization	NN
cord-008530-yni0poh9	260	15	of	of	IN
cord-008530-yni0poh9	260	16	the	the	DT
cord-008530-yni0poh9	260	17	fractalkine	fractalkine	JJ
cord-008530-yni0poh9	260	18	receptor	receptor	NN
cord-008530-yni0poh9	260	19	on	on	IN
cord-008530-yni0poh9	260	20	microglia	microglia	NNP
cord-008530-yni0poh9	260	21	and	and	CC
cord-008530-yni0poh9	260	22	the	the	DT
cord-008530-yni0poh9	260	23	expression	expression	NN
cord-008530-yni0poh9	260	24	of	of	IN
cord-008530-yni0poh9	260	25	its	-PRON-	PRP$
cord-008530-yni0poh9	260	26	ligand	ligand	NN
cord-008530-yni0poh9	260	27	by	by	IN
cord-008530-yni0poh9	260	28	neurons	neuron	NNS
cord-008530-yni0poh9	260	29	clearly	clearly	RB
cord-008530-yni0poh9	260	30	establish	establish	VBP
cord-008530-yni0poh9	260	31	a	a	DT
cord-008530-yni0poh9	260	32	spatial	spatial	JJ
cord-008530-yni0poh9	260	33	framework	framework	NN
cord-008530-yni0poh9	260	34	that	that	WDT
cord-008530-yni0poh9	260	35	could	could	MD
cord-008530-yni0poh9	260	36	facilitate	facilitate	VB
cord-008530-yni0poh9	260	37	juxtacrine	juxtacrine	NNP
cord-008530-yni0poh9	260	38	communication	communication	NN
cord-008530-yni0poh9	260	39	and	and	CC
cord-008530-yni0poh9	260	40	migration	migration	NN
cord-008530-yni0poh9	260	41	between	between	IN
cord-008530-yni0poh9	260	42	these	these	DT
cord-008530-yni0poh9	260	43	cells	cell	NNS
cord-008530-yni0poh9	260	44	(	(	-LRB-
cord-008530-yni0poh9	260	45	see	see	VB
cord-008530-yni0poh9	260	46	Fig	Fig	NNP
cord-008530-yni0poh9	260	47	.	.	.
cord-008530-yni0poh9	261	1	3	3	LS
cord-008530-yni0poh9	261	2	)	)	-RRB-
cord-008530-yni0poh9	262	1	Nishiyori	Nishiyori	NNP
cord-008530-yni0poh9	262	2	et	et	NNP
cord-008530-yni0poh9	262	3	al	al	NNP
cord-008530-yni0poh9	262	4	.	.	NNP
cord-008530-yni0poh9	262	5	,	,	,
cord-008530-yni0poh9	262	6	1998	1998	CD
cord-008530-yni0poh9	262	7	)	)	-RRB-
cord-008530-yni0poh9	262	8	.	.	.
cord-008530-yni0poh9	263	1	A	a	DT
cord-008530-yni0poh9	263	2	majority	majority	NN
cord-008530-yni0poh9	263	3	of	of	IN
cord-008530-yni0poh9	263	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	263	5	are	be	VBP
cord-008530-yni0poh9	263	6	not	not	RB
cord-008530-yni0poh9	263	7	detectable	detectable	JJ
cord-008530-yni0poh9	263	8	in	in	IN
cord-008530-yni0poh9	263	9	the	the	DT
cord-008530-yni0poh9	263	10	CNS	CNS	NNP
cord-008530-yni0poh9	263	11	under	under	IN
cord-008530-yni0poh9	263	12	physiological	physiological	JJ
cord-008530-yni0poh9	263	13	conditions	condition	NNS
cord-008530-yni0poh9	263	14	,	,	,
cord-008530-yni0poh9	263	15	but	but	CC
cord-008530-yni0poh9	263	16	are	be	VBP
cord-008530-yni0poh9	263	17	present	present	JJ
cord-008530-yni0poh9	263	18	during	during	IN
cord-008530-yni0poh9	263	19	diverse	diverse	JJ
cord-008530-yni0poh9	263	20	pathologic	pathologic	JJ
cord-008530-yni0poh9	263	21	states	state	NNS
cord-008530-yni0poh9	263	22	including	include	VBG
cord-008530-yni0poh9	263	23	,	,	,
cord-008530-yni0poh9	263	24	as	as	IN
cord-008530-yni0poh9	263	25	discussed	discuss	VBN
cord-008530-yni0poh9	263	26	below	below	RB
cord-008530-yni0poh9	263	27	,	,	,
cord-008530-yni0poh9	263	28	viral	viral	JJ
cord-008530-yni0poh9	263	29	diseases	disease	NNS
cord-008530-yni0poh9	263	30	.	.	.
cord-008530-yni0poh9	264	1	It	-PRON-	PRP
cord-008530-yni0poh9	264	2	is	be	VBZ
cord-008530-yni0poh9	264	3	beyond	beyond	IN
cord-008530-yni0poh9	264	4	the	the	DT
cord-008530-yni0poh9	264	5	scope	scope	NN
cord-008530-yni0poh9	264	6	of	of	IN
cord-008530-yni0poh9	264	7	this	this	DT
cord-008530-yni0poh9	264	8	chapter	chapter	NN
cord-008530-yni0poh9	264	9	to	to	TO
cord-008530-yni0poh9	264	10	detail	detail	VB
cord-008530-yni0poh9	264	11	all	all	DT
cord-008530-yni0poh9	264	12	of	of	IN
cord-008530-yni0poh9	264	13	the	the	DT
cord-008530-yni0poh9	264	14	findings	finding	NNS
cord-008530-yni0poh9	264	15	in	in	IN
cord-008530-yni0poh9	264	16	these	these	DT
cord-008530-yni0poh9	264	17	different	different	JJ
cord-008530-yni0poh9	264	18	pathologic	pathologic	JJ
cord-008530-yni0poh9	264	19	states	state	NNS
cord-008530-yni0poh9	264	20	and	and	CC
cord-008530-yni0poh9	264	21	the	the	DT
cord-008530-yni0poh9	264	22	reader	reader	NN
cord-008530-yni0poh9	264	23	is	be	VBZ
cord-008530-yni0poh9	264	24	encouraged	encourage	VBN
cord-008530-yni0poh9	264	25	to	to	TO
cord-008530-yni0poh9	264	26	consult	consult	VB
cord-008530-yni0poh9	264	27	many	many	JJ
cord-008530-yni0poh9	264	28	excellent	excellent	JJ
cord-008530-yni0poh9	264	29	recent	recent	JJ
cord-008530-yni0poh9	264	30	reviews	review	NNS
cord-008530-yni0poh9	264	31	dealing	deal	VBG
cord-008530-yni0poh9	264	32	with	with	IN
cord-008530-yni0poh9	264	33	this	this	DT
cord-008530-yni0poh9	264	34	subject	subject	NN
cord-008530-yni0poh9	264	35	(	(	-LRB-
cord-008530-yni0poh9	264	36	Asensio	Asensio	NNP
cord-008530-yni0poh9	264	37	and	and	CC
cord-008530-yni0poh9	264	38	Campbell	Campbell	NNP
cord-008530-yni0poh9	264	39	,	,	,
cord-008530-yni0poh9	264	40	1999	1999	CD
cord-008530-yni0poh9	264	41	;	;	:
cord-008530-yni0poh9	264	42	Glabinski	Glabinski	NNP
cord-008530-yni0poh9	264	43	and	and	CC
cord-008530-yni0poh9	264	44	Ransohoff	Ransohoff	NNP
cord-008530-yni0poh9	264	45	,	,	,
cord-008530-yni0poh9	264	46	1999	1999	CD
cord-008530-yni0poh9	264	47	;	;	:
cord-008530-yni0poh9	264	48	Karpus	Karpus	NNP
cord-008530-yni0poh9	264	49	and	and	CC
cord-008530-yni0poh9	264	50	Ransohoff	Ransohoff	NNP
cord-008530-yni0poh9	264	51	,	,	,
cord-008530-yni0poh9	264	52	1998	1998	CD
cord-008530-yni0poh9	264	53	;	;	:
cord-008530-yni0poh9	264	54	Mennicken	Mennicken	NNP
cord-008530-yni0poh9	264	55	et	et	NNP
cord-008530-yni0poh9	264	56	al	al	NNP
cord-008530-yni0poh9	264	57	.	.	NNP
cord-008530-yni0poh9	264	58	,	,	,
cord-008530-yni0poh9	264	59	1999	1999	CD
cord-008530-yni0poh9	264	60	;	;	:
cord-008530-yni0poh9	264	61	Ransohoff	Ransohoff	NNP
cord-008530-yni0poh9	264	62	,	,	,
cord-008530-yni0poh9	264	63	1997	1997	CD
cord-008530-yni0poh9	264	64	;	;	:
cord-008530-yni0poh9	264	65	Ransohoff	Ransohoff	NNP
cord-008530-yni0poh9	264	66	and	and	CC
cord-008530-yni0poh9	264	67	Tani	Tani	NNP
cord-008530-yni0poh9	264	68	,	,	,
cord-008530-yni0poh9	264	69	1998	1998	CD
cord-008530-yni0poh9	264	70	)	)	-RRB-
cord-008530-yni0poh9	264	71	.	.	.
cord-008530-yni0poh9	265	1	It	-PRON-	PRP
cord-008530-yni0poh9	265	2	is	be	VBZ
cord-008530-yni0poh9	265	3	clear	clear	JJ
cord-008530-yni0poh9	265	4	from	from	IN
cord-008530-yni0poh9	265	5	most	most	JJS
cord-008530-yni0poh9	265	6	,	,	,
cord-008530-yni0poh9	265	7	if	if	IN
cord-008530-yni0poh9	265	8	not	not	RB
cord-008530-yni0poh9	265	9	all	all	DT
cord-008530-yni0poh9	265	10	,	,	,
cord-008530-yni0poh9	265	11	cases	case	NNS
cord-008530-yni0poh9	265	12	examined	examine	VBD
cord-008530-yni0poh9	265	13	that	that	IN
cord-008530-yni0poh9	265	14	glial	glial	JJ
cord-008530-yni0poh9	265	15	cells	cell	NNS
cord-008530-yni0poh9	265	16	represent	represent	VBP
cord-008530-yni0poh9	265	17	an	an	DT
cord-008530-yni0poh9	265	18	important	important	JJ
cord-008530-yni0poh9	265	19	source	source	NN
cord-008530-yni0poh9	265	20	for	for	IN
cord-008530-yni0poh9	265	21	the	the	DT
cord-008530-yni0poh9	265	22	localized	localized	JJ
cord-008530-yni0poh9	265	23	production	production	NN
cord-008530-yni0poh9	265	24	of	of	IN
cord-008530-yni0poh9	265	25	specific	specific	JJ
cord-008530-yni0poh9	265	26	chemokines	chemokine	NNS
cord-008530-yni0poh9	265	27	.	.	.
cord-008530-yni0poh9	266	1	For	for	IN
cord-008530-yni0poh9	266	2	example	example	NN
cord-008530-yni0poh9	266	3	,	,	,
cord-008530-yni0poh9	266	4	in	in	IN
cord-008530-yni0poh9	266	5	MS	MS	NNP
cord-008530-yni0poh9	266	6	,	,	,
cord-008530-yni0poh9	266	7	expression	expression	NN
cord-008530-yni0poh9	266	8	of	of	IN
cord-008530-yni0poh9	266	9	IP-10	IP-10	NNP
cord-008530-yni0poh9	266	10	(	(	-LRB-
cord-008530-yni0poh9	266	11	Balashov	Balashov	NNP
cord-008530-yni0poh9	266	12	et	et	NNP
cord-008530-yni0poh9	266	13	al	al	NNP
cord-008530-yni0poh9	266	14	.	.	NNP
cord-008530-yni0poh9	266	15	,	,	,
cord-008530-yni0poh9	266	16	1999	1999	CD
cord-008530-yni0poh9	266	17	;	;	:
cord-008530-yni0poh9	266	18	Sorensen	Sorensen	NNP
cord-008530-yni0poh9	266	19	et	et	NNP
cord-008530-yni0poh9	266	20	al	al	NNP
cord-008530-yni0poh9	266	21	.	.	NNP
cord-008530-yni0poh9	266	22	,	,	,
cord-008530-yni0poh9	266	23	1999	1999	CD
cord-008530-yni0poh9	266	24	)	)	-RRB-
cord-008530-yni0poh9	266	25	and	and	CC
cord-008530-yni0poh9	266	26	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	266	27	(	(	-LRB-
cord-008530-yni0poh9	266	28	Simpson	Simpson	NNP
cord-008530-yni0poh9	266	29	et	et	NNP
cord-008530-yni0poh9	266	30	al	al	NNP
cord-008530-yni0poh9	266	31	.	.	NNP
cord-008530-yni0poh9	266	32	,	,	,
cord-008530-yni0poh9	266	33	1998	1998	CD
cord-008530-yni0poh9	266	34	;	;	:
cord-008530-yni0poh9	266	35	Van	Van	NNP
cord-008530-yni0poh9	266	36	Der	Der	NNP
cord-008530-yni0poh9	266	37	Voorn	Voorn	NNP
cord-008530-yni0poh9	266	38	et	et	FW
cord-008530-yni0poh9	266	39	al	al	NNP
cord-008530-yni0poh9	266	40	.	.	NNP
cord-008530-yni0poh9	266	41	,	,	,
cord-008530-yni0poh9	266	42	1999	1999	CD
cord-008530-yni0poh9	266	43	)	)	-RRB-
cord-008530-yni0poh9	266	44	is	be	VBZ
cord-008530-yni0poh9	266	45	prominent	prominent	JJ
cord-008530-yni0poh9	266	46	in	in	IN
cord-008530-yni0poh9	266	47	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	266	48	while	while	IN
cord-008530-yni0poh9	266	49	MIP	mip	NN
cord-008530-yni0poh9	266	50	-	-	HYPH
cord-008530-yni0poh9	266	51	I(~	i(~	CD
cord-008530-yni0poh9	266	52	expression	expression	NN
cord-008530-yni0poh9	266	53	is	be	VBZ
cord-008530-yni0poh9	266	54	strongly	strongly	RB
cord-008530-yni0poh9	266	55	associated	associate	VBN
cord-008530-yni0poh9	266	56	with	with	IN
cord-008530-yni0poh9	266	57	macrophage	macrophage	NN
cord-008530-yni0poh9	266	58	/	/	SYM
cord-008530-yni0poh9	266	59	microglia	microglia	NNS
cord-008530-yni0poh9	266	60	(	(	-LRB-
cord-008530-yni0poh9	266	61	Balashov	Balashov	NNP
cord-008530-yni0poh9	266	62	et	et	NNP
cord-008530-yni0poh9	266	63	al	al	NNP
cord-008530-yni0poh9	266	64	.	.	NNP
cord-008530-yni0poh9	266	65	,	,	,
cord-008530-yni0poh9	266	66	1999	1999	CD
cord-008530-yni0poh9	266	67	)	)	-RRB-
cord-008530-yni0poh9	266	68	.	.	.
cord-008530-yni0poh9	267	1	In	in	IN
cord-008530-yni0poh9	267	2	support	support	NN
cord-008530-yni0poh9	267	3	of	of	IN
cord-008530-yni0poh9	267	4	these	these	DT
cord-008530-yni0poh9	267	5	clinicopathologic	clinicopathologic	JJ
cord-008530-yni0poh9	267	6	findings	finding	NNS
cord-008530-yni0poh9	267	7	,	,	,
cord-008530-yni0poh9	267	8	studies	study	NNS
cord-008530-yni0poh9	267	9	in	in	IN
cord-008530-yni0poh9	267	10	vitro	vitro	FW
cord-008530-yni0poh9	267	11	demonstrate	demonstrate	VBP
cord-008530-yni0poh9	267	12	that	that	DT
cord-008530-yni0poh9	267	13	expression	expression	NN
cord-008530-yni0poh9	267	14	of	of	IN
cord-008530-yni0poh9	267	15	various	various	JJ
cord-008530-yni0poh9	267	16	CC	CC	NNP
cord-008530-yni0poh9	267	17	and	and	CC
cord-008530-yni0poh9	267	18	CXC	CXC	NNP
cord-008530-yni0poh9	267	19	chemokines	chemokine	NNS
cord-008530-yni0poh9	267	20	can	can	MD
cord-008530-yni0poh9	267	21	be	be	VB
cord-008530-yni0poh9	267	22	induced	induce	VBN
cord-008530-yni0poh9	267	23	in	in	IN
cord-008530-yni0poh9	267	24	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	267	25	and	and	CC
cord-008530-yni0poh9	267	26	microglia	microglia	NNS
cord-008530-yni0poh9	267	27	by	by	IN
cord-008530-yni0poh9	267	28	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	267	29	cytokines	cytokine	NNS
cord-008530-yni0poh9	267	30	and	and	CC
cord-008530-yni0poh9	267	31	LPS	lp	NNS
cord-008530-yni0poh9	267	32	.	.	.
cord-008530-yni0poh9	268	1	Although	although	IN
cord-008530-yni0poh9	268	2	differential	differential	JJ
cord-008530-yni0poh9	268	3	expression	expression	NN
cord-008530-yni0poh9	268	4	of	of	IN
cord-008530-yni0poh9	268	5	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	268	6	by	by	IN
cord-008530-yni0poh9	268	7	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	268	8	,	,	,
cord-008530-yni0poh9	268	9	and	and	CC
cord-008530-yni0poh9	268	10	of	of	IN
cord-008530-yni0poh9	268	11	MIP	MIP	NNP
cord-008530-yni0poh9	268	12	-	-	HYPH
cord-008530-yni0poh9	268	13	I(z	I(z	NNP
cord-008530-yni0poh9	268	14	by	by	IN
cord-008530-yni0poh9	268	15	microglia	microglia	NNP
cord-008530-yni0poh9	268	16	,	,	,
cord-008530-yni0poh9	268	17	was	be	VBD
cord-008530-yni0poh9	268	18	reported	report	VBN
cord-008530-yni0poh9	268	19	for	for	IN
cord-008530-yni0poh9	268	20	murine	murine	JJ
cord-008530-yni0poh9	268	21	glial	glial	JJ
cord-008530-yni0poh9	268	22	cells	cell	NNS
cord-008530-yni0poh9	268	23	(	(	-LRB-
cord-008530-yni0poh9	268	24	Hayashi	Hayashi	NNP
cord-008530-yni0poh9	268	25	et	et	FW
cord-008530-yni0poh9	268	26	al	al	NNP
cord-008530-yni0poh9	268	27	.	.	NNP
cord-008530-yni0poh9	268	28	,	,	,
cord-008530-yni0poh9	268	29	1995	1995	CD
cord-008530-yni0poh9	268	30	)	)	-RRB-
cord-008530-yni0poh9	268	31	,	,	,
cord-008530-yni0poh9	268	32	this	this	DT
cord-008530-yni0poh9	268	33	was	be	VBD
cord-008530-yni0poh9	268	34	not	not	RB
cord-008530-yni0poh9	268	35	the	the	DT
cord-008530-yni0poh9	268	36	case	case	NN
cord-008530-yni0poh9	268	37	with	with	IN
cord-008530-yni0poh9	268	38	human	human	JJ
cord-008530-yni0poh9	268	39	microglia	microglia	NNS
cord-008530-yni0poh9	268	40	,	,	,
cord-008530-yni0poh9	268	41	with	with	IN
cord-008530-yni0poh9	268	42	expression	expression	NN
cord-008530-yni0poh9	268	43	of	of	IN
cord-008530-yni0poh9	268	44	both	both	PDT
cord-008530-yni0poh9	268	45	these	these	DT
cord-008530-yni0poh9	268	46	chemokines	chemokine	NNS
cord-008530-yni0poh9	268	47	being	be	VBG
cord-008530-yni0poh9	268	48	induced	induce	VBN
cord-008530-yni0poh9	268	49	in	in	IN
cord-008530-yni0poh9	268	50	these	these	DT
cord-008530-yni0poh9	268	51	cells	cell	NNS
cord-008530-yni0poh9	268	52	by	by	IN
cord-008530-yni0poh9	268	53	LPS	LPS	NNP
cord-008530-yni0poh9	268	54	(	(	-LRB-
cord-008530-yni0poh9	268	55	McManus	McManus	NNP
cord-008530-yni0poh9	268	56	et	et	NNP
cord-008530-yni0poh9	268	57	al	al	NNP
cord-008530-yni0poh9	268	58	.	.	NNP
cord-008530-yni0poh9	268	59	,	,	,
cord-008530-yni0poh9	268	60	1998	1998	CD
cord-008530-yni0poh9	268	61	)	)	-RRB-
cord-008530-yni0poh9	268	62	.	.	.
cord-008530-yni0poh9	269	1	Similarly	similarly	RB
cord-008530-yni0poh9	269	2	,	,	,
cord-008530-yni0poh9	269	3	expression	expression	NN
cord-008530-yni0poh9	269	4	of	of	IN
cord-008530-yni0poh9	269	5	IP-10	IP-10	NNP
cord-008530-yni0poh9	269	6	by	by	IN
cord-008530-yni0poh9	269	7	murine	murine	JJ
cord-008530-yni0poh9	269	8	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	269	9	and	and	CC
cord-008530-yni0poh9	269	10	microglia	microglia	NNS
cord-008530-yni0poh9	269	11	can	can	MD
cord-008530-yni0poh9	269	12	be	be	VB
cord-008530-yni0poh9	269	13	induced	induce	VBN
cord-008530-yni0poh9	269	14	by	by	IN
cord-008530-yni0poh9	269	15	IFN-~/or	IFN-~/or	NNP
cord-008530-yni0poh9	269	16	LPS	LPS	NNP
cord-008530-yni0poh9	269	17	(	(	-LRB-
cord-008530-yni0poh9	269	18	Luo	Luo	NNP
cord-008530-yni0poh9	269	19	et	et	NNP
cord-008530-yni0poh9	269	20	al	al	NNP
cord-008530-yni0poh9	269	21	.	.	NNP
cord-008530-yni0poh9	269	22	,	,	,
cord-008530-yni0poh9	269	23	1998	1998	CD
cord-008530-yni0poh9	269	24	;	;	:
cord-008530-yni0poh9	269	25	Majumder	Majumder	NNP
cord-008530-yni0poh9	269	26	et	et	NNP
cord-008530-yni0poh9	269	27	al	al	NNP
cord-008530-yni0poh9	269	28	.	.	.
cord-008530-yni0poh9	270	1	,	,	,
cord-008530-yni0poh9	270	2	1998	1998	CD
cord-008530-yni0poh9	270	3	;	;	:
cord-008530-yni0poh9	270	4	Ren	Ren	NNP
cord-008530-yni0poh9	270	5	et	et	NNP
cord-008530-yni0poh9	270	6	al	al	NNP
cord-008530-yni0poh9	270	7	.	.	NNP
cord-008530-yni0poh9	270	8	,	,	,
cord-008530-yni0poh9	270	9	1998	1998	CD
cord-008530-yni0poh9	270	10	;	;	:
cord-008530-yni0poh9	270	11	Vanguri	Vanguri	NNP
cord-008530-yni0poh9	270	12	,	,	,
cord-008530-yni0poh9	270	13	1995	1995	CD
cord-008530-yni0poh9	270	14	)	)	-RRB-
cord-008530-yni0poh9	270	15	.	.	.
cord-008530-yni0poh9	271	1	In	in	IN
cord-008530-yni0poh9	271	2	contrast	contrast	NN
cord-008530-yni0poh9	271	3	to	to	IN
cord-008530-yni0poh9	271	4	the	the	DT
cord-008530-yni0poh9	271	5	glial	glial	JJ
cord-008530-yni0poh9	271	6	cells	cell	NNS
cord-008530-yni0poh9	271	7	,	,	,
cord-008530-yni0poh9	271	8	few	few	JJ
cord-008530-yni0poh9	271	9	inducible	inducible	JJ
cord-008530-yni0poh9	271	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	271	11	have	have	VBP
cord-008530-yni0poh9	271	12	been	be	VBN
cord-008530-yni0poh9	271	13	reported	report	VBN
cord-008530-yni0poh9	271	14	to	to	TO
cord-008530-yni0poh9	271	15	be	be	VB
cord-008530-yni0poh9	271	16	expressed	express	VBN
cord-008530-yni0poh9	271	17	by	by	IN
cord-008530-yni0poh9	271	18	neuronal	neuronal	JJ
cord-008530-yni0poh9	271	19	cells	cell	NNS
cord-008530-yni0poh9	271	20	either	either	CC
cord-008530-yni0poh9	271	21	in	in	IN
cord-008530-yni0poh9	271	22	vitro	vitro	FW
cord-008530-yni0poh9	271	23	or	or	CC
cord-008530-yni0poh9	271	24	in	in	IN
cord-008530-yni0poh9	271	25	vivo	vivo	NNP
cord-008530-yni0poh9	271	26	.	.	.
cord-008530-yni0poh9	272	1	How	how	WRB
cord-008530-yni0poh9	272	2	does	do	VBZ
cord-008530-yni0poh9	272	3	CNS	CNS	NNP
cord-008530-yni0poh9	272	4	chemokine	chemokine	NN
cord-008530-yni0poh9	272	5	expression	expression	NN
cord-008530-yni0poh9	272	6	contribute	contribute	VB
cord-008530-yni0poh9	272	7	to	to	IN
cord-008530-yni0poh9	272	8	the	the	DT
cord-008530-yni0poh9	272	9	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	272	10	of	of	IN
cord-008530-yni0poh9	272	11	neuroinflammatory	neuroinflammatory	NNP
cord-008530-yni0poh9	272	12	disease	disease	NNP
cord-008530-yni0poh9	272	13	states	state	NNS
cord-008530-yni0poh9	272	14	?	?	.
cord-008530-yni0poh9	273	1	Clearly	clearly	RB
cord-008530-yni0poh9	273	2	,	,	,
cord-008530-yni0poh9	273	3	one	one	CD
cord-008530-yni0poh9	273	4	key	key	JJ
cord-008530-yni0poh9	273	5	role	role	NN
cord-008530-yni0poh9	273	6	involves	involve	VBZ
cord-008530-yni0poh9	273	7	recruitment	recruitment	NN
cord-008530-yni0poh9	273	8	of	of	IN
cord-008530-yni0poh9	273	9	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	273	10	to	to	IN
cord-008530-yni0poh9	273	11	the	the	DT
cord-008530-yni0poh9	273	12	brain	brain	NN
cord-008530-yni0poh9	273	13	.	.	.
cord-008530-yni0poh9	274	1	Differences	difference	NNS
cord-008530-yni0poh9	274	2	in	in	IN
cord-008530-yni0poh9	274	3	the	the	DT
cord-008530-yni0poh9	274	4	chemokine	chemokine	NN
cord-008530-yni0poh9	274	5	gene	gene	NN
cord-008530-yni0poh9	274	6	expression	expression	NN
cord-008530-yni0poh9	274	7	patterns	pattern	NNS
cord-008530-yni0poh9	274	8	can	can	MD
cord-008530-yni0poh9	274	9	be	be	VB
cord-008530-yni0poh9	274	10	found	find	VBN
cord-008530-yni0poh9	274	11	in	in	IN
cord-008530-yni0poh9	274	12	different	different	JJ
cord-008530-yni0poh9	274	13	neuroinflammatory	neuroinflammatory	NN
cord-008530-yni0poh9	274	14	diseases	disease	NNS
cord-008530-yni0poh9	274	15	and	and	CC
cord-008530-yni0poh9	274	16	correlate	correlate	VBP
cord-008530-yni0poh9	274	17	with	with	IN
cord-008530-yni0poh9	274	18	a	a	DT
cord-008530-yni0poh9	274	19	bias	bias	NN
cord-008530-yni0poh9	274	20	toward	toward	IN
cord-008530-yni0poh9	274	21	the	the	DT
cord-008530-yni0poh9	274	22	involvement	involvement	NN
cord-008530-yni0poh9	274	23	of	of	IN
cord-008530-yni0poh9	274	24	particular	particular	JJ
cord-008530-yni0poh9	274	25	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	274	26	.	.	.
cord-008530-yni0poh9	275	1	In	in	IN
cord-008530-yni0poh9	275	2	experimental	experimental	JJ
cord-008530-yni0poh9	275	3	and	and	CC
cord-008530-yni0poh9	275	4	clinical	clinical	JJ
cord-008530-yni0poh9	275	5	bacterial	bacterial	NN
cord-008530-yni0poh9	275	6	meningoencephalitis	meningoencephalitis	NN
cord-008530-yni0poh9	275	7	,	,	,
cord-008530-yni0poh9	275	8	where	where	WRB
cord-008530-yni0poh9	275	9	CNS	CNS	NNP
cord-008530-yni0poh9	275	10	lesions	lesion	NNS
cord-008530-yni0poh9	275	11	consist	consist	VBP
cord-008530-yni0poh9	275	12	predominantly	predominantly	RB
cord-008530-yni0poh9	275	13	of	of	IN
cord-008530-yni0poh9	275	14	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	275	15	and	and	CC
cord-008530-yni0poh9	275	16	monocytes	monocyte	NNS
cord-008530-yni0poh9	275	17	,	,	,
cord-008530-yni0poh9	275	18	there	there	EX
cord-008530-yni0poh9	275	19	is	be	VBZ
cord-008530-yni0poh9	275	20	dominant	dominant	JJ
cord-008530-yni0poh9	275	21	cerebral	cerebral	JJ
cord-008530-yni0poh9	275	22	production	production	NN
cord-008530-yni0poh9	275	23	of	of	IN
cord-008530-yni0poh9	275	24	the	the	DT
cord-008530-yni0poh9	275	25	neutrophil	neutrophil	NN
cord-008530-yni0poh9	275	26	and	and	CC
cord-008530-yni0poh9	275	27	monocyte	monocyte	NNP
cord-008530-yni0poh9	275	28	attractant	attractant	NN
cord-008530-yni0poh9	275	29	chemokines	chemokines	NNPS
cord-008530-yni0poh9	276	1	IL-8	IL-8	NNP
cord-008530-yni0poh9	276	2	,	,	,
cord-008530-yni0poh9	276	3	MIP-2	MIP-2	NNP
cord-008530-yni0poh9	276	4	,	,	,
cord-008530-yni0poh9	276	5	and	and	CC
cord-008530-yni0poh9	276	6	GROa	GROa	NNS
cord-008530-yni0poh9	276	7	,	,	,
cord-008530-yni0poh9	276	8	and	and	CC
cord-008530-yni0poh9	276	9	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	276	10	,	,	,
cord-008530-yni0poh9	276	11	MIP	MIP	NNP
cord-008530-yni0poh9	276	12	-	-	HYPH
cord-008530-yni0poh9	276	13	I~	I~	NNP
cord-008530-yni0poh9	276	14	,	,	,
cord-008530-yni0poh9	276	15	and	and	CC
cord-008530-yni0poh9	276	16	MIP	MIP	NNP
cord-008530-yni0poh9	276	17	-	-	HYPH
cord-008530-yni0poh9	276	18	I~	I~	NNP
cord-008530-yni0poh9	276	19	,	,	,
cord-008530-yni0poh9	276	20	respectively	respectively	RB
cord-008530-yni0poh9	276	21	(	(	-LRB-
cord-008530-yni0poh9	276	22	Lahrtz	Lahrtz	NNP
cord-008530-yni0poh9	276	23	et	et	FW
cord-008530-yni0poh9	276	24	al	al	NNP
cord-008530-yni0poh9	276	25	.	.	.
cord-008530-yni0poh9	277	1	,	,	,
cord-008530-yni0poh9	277	2	1998	1998	CD
cord-008530-yni0poh9	277	3	;	;	:
cord-008530-yni0poh9	277	4	Spanaus	Spanaus	NNP
cord-008530-yni0poh9	277	5	et	et	NNP
cord-008530-yni0poh9	277	6	al	al	NNP
cord-008530-yni0poh9	277	7	.	.	NNP
cord-008530-yni0poh9	277	8	,	,	,
cord-008530-yni0poh9	277	9	1997	1997	CD
cord-008530-yni0poh9	278	1	;	;	:
cord-008530-yni0poh9	278	2	Sprenger	Sprenger	NNP
cord-008530-yni0poh9	278	3	et	et	NNP
cord-008530-yni0poh9	278	4	al	al	NNP
cord-008530-yni0poh9	278	5	.	.	NNP
cord-008530-yni0poh9	278	6	,	,	,
cord-008530-yni0poh9	278	7	1996	1996	CD
cord-008530-yni0poh9	278	8	)	)	-RRB-
cord-008530-yni0poh9	278	9	.	.	.
cord-008530-yni0poh9	279	1	In	in	IN
cord-008530-yni0poh9	279	2	contrast	contrast	NN
cord-008530-yni0poh9	279	3	,	,	,
cord-008530-yni0poh9	279	4	as	as	IN
cord-008530-yni0poh9	279	5	discussed	discuss	VBN
cord-008530-yni0poh9	279	6	below	below	RB
cord-008530-yni0poh9	279	7	,	,	,
cord-008530-yni0poh9	279	8	in	in	IN
cord-008530-yni0poh9	279	9	viral	viral	JJ
cord-008530-yni0poh9	279	10	meningoencephalitis	meningoencephalitis	NN
cord-008530-yni0poh9	279	11	,	,	,
cord-008530-yni0poh9	279	12	mostly	mostly	RB
cord-008530-yni0poh9	279	13	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	279	14	and	and	CC
cord-008530-yni0poh9	279	15	monocytes	monocyte	NNS
cord-008530-yni0poh9	279	16	are	be	VBP
cord-008530-yni0poh9	279	17	found	find	VBN
cord-008530-yni0poh9	279	18	in	in	IN
cord-008530-yni0poh9	279	19	the	the	DT
cord-008530-yni0poh9	279	20	CNS	CNS	NNP
cord-008530-yni0poh9	279	21	,	,	,
cord-008530-yni0poh9	279	22	in	in	IN
cord-008530-yni0poh9	279	23	parallel	parallel	NN
cord-008530-yni0poh9	279	24	with	with	IN
cord-008530-yni0poh9	279	25	the	the	DT
cord-008530-yni0poh9	279	26	cerebral	cerebral	JJ
cord-008530-yni0poh9	279	27	expression	expression	NN
cord-008530-yni0poh9	279	28	of	of	IN
cord-008530-yni0poh9	279	29	the	the	DT
cord-008530-yni0poh9	279	30	chemokine	chemokine	NN
cord-008530-yni0poh9	279	31	genes	gene	NNS
cord-008530-yni0poh9	279	32	encoding	encode	VBG
cord-008530-yni0poh9	279	33	IP-10	IP-10	NNP
cord-008530-yni0poh9	279	34	,	,	,
cord-008530-yni0poh9	279	35	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	279	36	,	,	,
cord-008530-yni0poh9	279	37	and	and	CC
cord-008530-yni0poh9	279	38	RANTES	RANTES	NNP
cord-008530-yni0poh9	279	39	,	,	,
cord-008530-yni0poh9	279	40	which	which	WDT
cord-008530-yni0poh9	279	41	are	be	VBP
cord-008530-yni0poh9	279	42	effective	effective	JJ
cord-008530-yni0poh9	279	43	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	279	44	and	and	CC
cord-008530-yni0poh9	279	45	monocyte	monocyte	NNP
cord-008530-yni0poh9	279	46	chemoattractants	chemoattractant	NNS
cord-008530-yni0poh9	279	47	(	(	-LRB-
cord-008530-yni0poh9	279	48	Asensio	Asensio	NNP
cord-008530-yni0poh9	279	49	and	and	CC
cord-008530-yni0poh9	279	50	Campbell	Campbell	NNP
cord-008530-yni0poh9	279	51	,	,	,
cord-008530-yni0poh9	279	52	1997	1997	CD
cord-008530-yni0poh9	279	53	;	;	:
cord-008530-yni0poh9	279	54	Lahrtz	Lahrtz	NNP
cord-008530-yni0poh9	279	55	et	et	FW
cord-008530-yni0poh9	279	56	al	al	NNP
cord-008530-yni0poh9	279	57	.	.	NNP
cord-008530-yni0poh9	279	58	,	,	,
cord-008530-yni0poh9	279	59	1997	1997	CD
cord-008530-yni0poh9	279	60	)	)	-RRB-
cord-008530-yni0poh9	279	61	.	.	.
cord-008530-yni0poh9	280	1	Transgenic	transgenic	JJ
cord-008530-yni0poh9	280	2	studies	study	NNS
cord-008530-yni0poh9	280	3	show	show	VBP
cord-008530-yni0poh9	280	4	that	that	IN
cord-008530-yni0poh9	280	5	individual	individual	JJ
cord-008530-yni0poh9	280	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	280	7	can	can	MD
cord-008530-yni0poh9	280	8	have	have	VB
cord-008530-yni0poh9	280	9	a	a	DT
cord-008530-yni0poh9	280	10	specific	specific	JJ
cord-008530-yni0poh9	280	11	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	280	12	"	"	''
cord-008530-yni0poh9	280	13	signature	signature	NN
cord-008530-yni0poh9	280	14	.	.	.
cord-008530-yni0poh9	280	15	"	"	''
cord-008530-yni0poh9	281	1	Thus	thus	RB
cord-008530-yni0poh9	281	2	,	,	,
cord-008530-yni0poh9	281	3	CNS	cns	JJ
cord-008530-yni0poh9	281	4	expression	expression	NN
cord-008530-yni0poh9	281	5	of	of	IN
cord-008530-yni0poh9	281	6	either	either	CC
cord-008530-yni0poh9	281	7	the	the	DT
cord-008530-yni0poh9	281	8	GROa	GROa	NNP
cord-008530-yni0poh9	281	9	genes	gene	NNS
cord-008530-yni0poh9	281	10	(	(	-LRB-
cord-008530-yni0poh9	281	11	Tani	Tani	NNP
cord-008530-yni0poh9	281	12	et	et	NNP
cord-008530-yni0poh9	281	13	al	al	NNP
cord-008530-yni0poh9	281	14	.	.	NNP
cord-008530-yni0poh9	281	15	,	,	,
cord-008530-yni0poh9	281	16	1996	1996	CD
cord-008530-yni0poh9	281	17	)	)	-RRB-
cord-008530-yni0poh9	281	18	or	or	CC
cord-008530-yni0poh9	281	19	the	the	DT
cord-008530-yni0poh9	281	20	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	281	21	genes	gene	NNS
cord-008530-yni0poh9	281	22	(	(	-LRB-
cord-008530-yni0poh9	281	23	Fuentes	Fuentes	NNPS
cord-008530-yni0poh9	281	24	et	et	NNP
cord-008530-yni0poh9	281	25	al	al	NNP
cord-008530-yni0poh9	281	26	.	.	NNP
cord-008530-yni0poh9	281	27	,	,	,
cord-008530-yni0poh9	281	28	1995	1995	CD
cord-008530-yni0poh9	281	29	)	)	-RRB-
cord-008530-yni0poh9	281	30	under	under	IN
cord-008530-yni0poh9	281	31	the	the	DT
cord-008530-yni0poh9	281	32	control	control	NN
cord-008530-yni0poh9	281	33	of	of	IN
cord-008530-yni0poh9	281	34	the	the	DT
cord-008530-yni0poh9	281	35	myelin	myelin	JJ
cord-008530-yni0poh9	281	36	basic	basic	JJ
cord-008530-yni0poh9	281	37	protein	protein	NN
cord-008530-yni0poh9	281	38	(	(	-LRB-
cord-008530-yni0poh9	281	39	MBP	MBP	NNP
cord-008530-yni0poh9	281	40	)	)	-RRB-
cord-008530-yni0poh9	281	41	promoter	promoter	NN
cord-008530-yni0poh9	281	42	induces	induce	VBZ
cord-008530-yni0poh9	281	43	robust	robust	JJ
cord-008530-yni0poh9	281	44	leukocyte	leukocyte	NN
cord-008530-yni0poh9	281	45	infiltration	infiltration	NN
cord-008530-yni0poh9	281	46	of	of	IN
cord-008530-yni0poh9	281	47	the	the	DT
cord-008530-yni0poh9	281	48	CNS	CNS	NNP
cord-008530-yni0poh9	281	49	that	that	WDT
cord-008530-yni0poh9	281	50	is	be	VBZ
cord-008530-yni0poh9	281	51	composed	compose	VBN
cord-008530-yni0poh9	281	52	predominantly	predominantly	RB
cord-008530-yni0poh9	281	53	of	of	IN
cord-008530-yni0poh9	281	54	either	either	CC
cord-008530-yni0poh9	281	55	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	281	56	or	or	CC
cord-008530-yni0poh9	281	57	monocytes	monocyte	NNS
cord-008530-yni0poh9	281	58	,	,	,
cord-008530-yni0poh9	281	59	respectively	respectively	RB
cord-008530-yni0poh9	281	60	.	.	.
cord-008530-yni0poh9	282	1	Studies	study	NNS
cord-008530-yni0poh9	282	2	with	with	IN
cord-008530-yni0poh9	282	3	intracerebral	intracerebral	JJ
cord-008530-yni0poh9	282	4	microinjection	microinjection	NN
cord-008530-yni0poh9	282	5	also	also	RB
cord-008530-yni0poh9	282	6	demonstrate	demonstrate	VBP
cord-008530-yni0poh9	282	7	that	that	IN
cord-008530-yni0poh9	282	8	the	the	DT
cord-008530-yni0poh9	282	9	acute	acute	JJ
cord-008530-yni0poh9	282	10	presence	presence	NN
cord-008530-yni0poh9	282	11	of	of	IN
cord-008530-yni0poh9	282	12	chemokines	chemokine	NNS
cord-008530-yni0poh9	282	13	in	in	IN
cord-008530-yni0poh9	282	14	the	the	DT
cord-008530-yni0poh9	282	15	CNS	CNS	NNP
cord-008530-yni0poh9	282	16	leads	lead	VBZ
cord-008530-yni0poh9	282	17	to	to	TO
cord-008530-yni0poh9	282	18	robust	robust	JJ
cord-008530-yni0poh9	282	19	and	and	CC
cord-008530-yni0poh9	282	20	cell	cell	NN
cord-008530-yni0poh9	282	21	-	-	HYPH
cord-008530-yni0poh9	282	22	specific	specific	JJ
cord-008530-yni0poh9	282	23	leukocyte	leukocyte	NN
cord-008530-yni0poh9	282	24	recruitment	recruitment	NN
cord-008530-yni0poh9	282	25	.	.	.
cord-008530-yni0poh9	283	1	For	for	IN
cord-008530-yni0poh9	283	2	example	example	NN
cord-008530-yni0poh9	283	3	,	,	,
cord-008530-yni0poh9	283	4	MIP-2	MIP-2	NNP
cord-008530-yni0poh9	283	5	is	be	VBZ
cord-008530-yni0poh9	283	6	more	more	RBR
cord-008530-yni0poh9	283	7	potent	potent	JJ
cord-008530-yni0poh9	283	8	than	than	IN
cord-008530-yni0poh9	283	9	IL-8	IL-8	NNP
cord-008530-yni0poh9	283	10	,	,	,
cord-008530-yni0poh9	283	11	IP-10	IP-10	NNP
cord-008530-yni0poh9	283	12	,	,	,
cord-008530-yni0poh9	283	13	or	or	CC
cord-008530-yni0poh9	283	14	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	283	15	in	in	IN
cord-008530-yni0poh9	283	16	stimulating	stimulate	VBG
cord-008530-yni0poh9	283	17	polymorphonu-	polymorphonu-	NN
cord-008530-yni0poh9	283	18	VAL]~RIE	VAL]~RIE	NNP
cord-008530-yni0poh9	283	19	C.	C.	NNP
cord-008530-yni0poh9	283	20	ASENSIO	ASENSIO	NNP
cord-008530-yni0poh9	283	21	AND	and	CC
cord-008530-yni0poh9	283	22	IAIN	IAIN	NNP
cord-008530-yni0poh9	283	23	L.	L.	NNP
cord-008530-yni0poh9	283	24	CAMPBELL	CAMPBELL	NNP
cord-008530-yni0poh9	283	25	clear	clear	JJ
cord-008530-yni0poh9	283	26	leukocyte	leukocyte	NN
cord-008530-yni0poh9	283	27	recruitment	recruitment	NN
cord-008530-yni0poh9	283	28	to	to	IN
cord-008530-yni0poh9	283	29	the	the	DT
cord-008530-yni0poh9	283	30	brain	brain	NN
cord-008530-yni0poh9	284	1	(	(	-LRB-
cord-008530-yni0poh9	284	2	Bell	Bell	NNP
cord-008530-yni0poh9	284	3	et	et	NNP
cord-008530-yni0poh9	284	4	al	al	NNP
cord-008530-yni0poh9	284	5	.	.	NNP
cord-008530-yni0poh9	284	6	,	,	,
cord-008530-yni0poh9	284	7	1996	1996	CD
cord-008530-yni0poh9	284	8	)	)	-RRB-
cord-008530-yni0poh9	284	9	,	,	,
cord-008530-yni0poh9	284	10	while	while	IN
cord-008530-yni0poh9	284	11	the	the	DT
cord-008530-yni0poh9	284	12	CC	cc	NN
cord-008530-yni0poh9	284	13	chemokine	chemokine	NN
cord-008530-yni0poh9	284	14	C10	C10	NNP
cord-008530-yni0poh9	284	15	,	,	,
cord-008530-yni0poh9	284	16	when	when	WRB
cord-008530-yni0poh9	284	17	injected	inject	VBN
cord-008530-yni0poh9	284	18	into	into	IN
cord-008530-yni0poh9	284	19	the	the	DT
cord-008530-yni0poh9	284	20	lateral	lateral	JJ
cord-008530-yni0poh9	284	21	ventricle	ventricle	NN
cord-008530-yni0poh9	284	22	,	,	,
cord-008530-yni0poh9	284	23	is	be	VBZ
cord-008530-yni0poh9	284	24	able	able	JJ
cord-008530-yni0poh9	284	25	to	to	TO
cord-008530-yni0poh9	284	26	induce	induce	VB
cord-008530-yni0poh9	284	27	a	a	DT
cord-008530-yni0poh9	284	28	recruitment	recruitment	NN
cord-008530-yni0poh9	284	29	of	of	IN
cord-008530-yni0poh9	284	30	macrophages	macrophage	NNS
cord-008530-yni0poh9	284	31	,	,	,
cord-008530-yni0poh9	284	32	but	but	CC
cord-008530-yni0poh9	284	33	not	not	RB
cord-008530-yni0poh9	284	34	T	t	NN
cord-008530-yni0poh9	284	35	cells	cell	NNS
cord-008530-yni0poh9	284	36	(	(	-LRB-
cord-008530-yni0poh9	284	37	Asensio	Asensio	NNP
cord-008530-yni0poh9	284	38	et	et	NNP
cord-008530-yni0poh9	284	39	al	al	NNP
cord-008530-yni0poh9	284	40	.	.	NNP
cord-008530-yni0poh9	284	41	,	,	,
cord-008530-yni0poh9	284	42	1999b	1999b	CD
cord-008530-yni0poh9	284	43	)	)	-RRB-
cord-008530-yni0poh9	284	44	.	.	.
cord-008530-yni0poh9	285	1	Finally	finally	RB
cord-008530-yni0poh9	285	2	,	,	,
cord-008530-yni0poh9	285	3	neutralization	neutralization	NN
cord-008530-yni0poh9	285	4	of	of	IN
cord-008530-yni0poh9	285	5	the	the	DT
cord-008530-yni0poh9	285	6	chemokine	chemokine	NN
cord-008530-yni0poh9	285	7	MIP	MIP	NNP
cord-008530-yni0poh9	285	8	-	-	HYPH
cord-008530-yni0poh9	285	9	la	la	NNP
cord-008530-yni0poh9	285	10	,	,	,
cord-008530-yni0poh9	285	11	which	which	WDT
cord-008530-yni0poh9	285	12	is	be	VBZ
cord-008530-yni0poh9	285	13	expressed	express	VBN
cord-008530-yni0poh9	285	14	in	in	IN
cord-008530-yni0poh9	285	15	EAE	EAE	NNP
cord-008530-yni0poh9	285	16	,	,	,
cord-008530-yni0poh9	285	17	is	be	VBZ
cord-008530-yni0poh9	285	18	associated	associate	VBN
cord-008530-yni0poh9	285	19	with	with	IN
cord-008530-yni0poh9	285	20	a	a	DT
cord-008530-yni0poh9	285	21	reduction	reduction	NN
cord-008530-yni0poh9	285	22	in	in	IN
cord-008530-yni0poh9	285	23	disease	disease	NN
cord-008530-yni0poh9	285	24	severity	severity	NN
cord-008530-yni0poh9	285	25	and	and	CC
cord-008530-yni0poh9	285	26	in	in	IN
cord-008530-yni0poh9	285	27	CNS	CNS	NNP
cord-008530-yni0poh9	285	28	inflammation	inflammation	NN
cord-008530-yni0poh9	286	1	(	(	-LRB-
cord-008530-yni0poh9	286	2	Karpus	Karpus	NNP
cord-008530-yni0poh9	286	3	et	et	NNP
cord-008530-yni0poh9	286	4	al	al	NNP
cord-008530-yni0poh9	286	5	.	.	NNP
cord-008530-yni0poh9	286	6	,	,	,
cord-008530-yni0poh9	286	7	1995	1995	CD
cord-008530-yni0poh9	286	8	)	)	-RRB-
cord-008530-yni0poh9	286	9	.	.	.
cord-008530-yni0poh9	287	1	In	in	IN
cord-008530-yni0poh9	287	2	all	all	DT
cord-008530-yni0poh9	287	3	,	,	,
cord-008530-yni0poh9	287	4	these	these	DT
cord-008530-yni0poh9	287	5	studies	study	NNS
cord-008530-yni0poh9	287	6	indicate	indicate	VBP
cord-008530-yni0poh9	287	7	that	that	IN
cord-008530-yni0poh9	287	8	the	the	DT
cord-008530-yni0poh9	287	9	qualitative	qualitative	JJ
cord-008530-yni0poh9	287	10	makeup	makeup	NN
cord-008530-yni0poh9	287	11	of	of	IN
cord-008530-yni0poh9	287	12	chemokine	chemokine	NN
cord-008530-yni0poh9	287	13	production	production	NN
cord-008530-yni0poh9	287	14	in	in	IN
cord-008530-yni0poh9	287	15	the	the	DT
cord-008530-yni0poh9	287	16	CNS	CNS	NNP
cord-008530-yni0poh9	287	17	during	during	IN
cord-008530-yni0poh9	287	18	disease	disease	NN
cord-008530-yni0poh9	287	19	can	can	MD
cord-008530-yni0poh9	287	20	dictate	dictate	VB
cord-008530-yni0poh9	287	21	the	the	DT
cord-008530-yni0poh9	287	22	recruitment	recruitment	NN
cord-008530-yni0poh9	287	23	of	of	IN
cord-008530-yni0poh9	287	24	selected	select	VBN
cord-008530-yni0poh9	287	25	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	287	26	to	to	IN
cord-008530-yni0poh9	287	27	the	the	DT
cord-008530-yni0poh9	287	28	CNS	CNS	NNP
cord-008530-yni0poh9	287	29	,	,	,
cord-008530-yni0poh9	287	30	and	and	CC
cord-008530-yni0poh9	287	31	that	that	IN
cord-008530-yni0poh9	287	32	targeting	target	VBG
cord-008530-yni0poh9	287	33	these	these	DT
cord-008530-yni0poh9	287	34	molecules	molecule	NNS
cord-008530-yni0poh9	287	35	may	may	MD
cord-008530-yni0poh9	287	36	provide	provide	VB
cord-008530-yni0poh9	287	37	an	an	DT
cord-008530-yni0poh9	287	38	effective	effective	JJ
cord-008530-yni0poh9	287	39	therapeutic	therapeutic	JJ
cord-008530-yni0poh9	287	40	approach	approach	NN
cord-008530-yni0poh9	287	41	to	to	TO
cord-008530-yni0poh9	287	42	suppress	suppress	VB
cord-008530-yni0poh9	287	43	CNS	CNS	NNP
cord-008530-yni0poh9	287	44	inflammation	inflammation	NN
cord-008530-yni0poh9	287	45	.	.	.
cord-008530-yni0poh9	288	1	The	the	DT
cord-008530-yni0poh9	288	2	CC	CC	NNP
cord-008530-yni0poh9	288	3	and	and	CC
cord-008530-yni0poh9	288	4	CXC	CXC	NNP
cord-008530-yni0poh9	288	5	receptors	receptor	NNS
cord-008530-yni0poh9	288	6	are	be	VBP
cord-008530-yni0poh9	288	7	expressed	express	VBN
cord-008530-yni0poh9	288	8	on	on	IN
cord-008530-yni0poh9	288	9	a	a	DT
cord-008530-yni0poh9	288	10	number	number	NN
cord-008530-yni0poh9	288	11	of	of	IN
cord-008530-yni0poh9	288	12	different	different	JJ
cord-008530-yni0poh9	288	13	cell	cell	NN
cord-008530-yni0poh9	288	14	types	type	NNS
cord-008530-yni0poh9	288	15	and	and	CC
cord-008530-yni0poh9	288	16	their	-PRON-	PRP$
cord-008530-yni0poh9	288	17	expression	expression	NN
cord-008530-yni0poh9	288	18	is	be	VBZ
cord-008530-yni0poh9	288	19	often	often	RB
cord-008530-yni0poh9	288	20	regulated	regulate	VBN
cord-008530-yni0poh9	288	21	by	by	IN
cord-008530-yni0poh9	288	22	exogenous	exogenous	JJ
cord-008530-yni0poh9	288	23	and	and	CC
cord-008530-yni0poh9	288	24	endogenous	endogenous	JJ
cord-008530-yni0poh9	288	25	stimuli	stimulus	NNS
cord-008530-yni0poh9	288	26	.	.	.
cord-008530-yni0poh9	289	1	Numerous	numerous	JJ
cord-008530-yni0poh9	289	2	in	in	IN
cord-008530-yni0poh9	289	3	vitro	vitro	FW
cord-008530-yni0poh9	289	4	and	and	CC
cord-008530-yni0poh9	289	5	in	in	IN
cord-008530-yni0poh9	289	6	vivo	vivo	NNP
cord-008530-yni0poh9	289	7	studies	study	NNS
cord-008530-yni0poh9	289	8	show	show	VBP
cord-008530-yni0poh9	289	9	that	that	IN
cord-008530-yni0poh9	289	10	different	different	JJ
cord-008530-yni0poh9	289	11	neural	neural	JJ
cord-008530-yni0poh9	289	12	cells	cell	NNS
cord-008530-yni0poh9	289	13	express	express	VBP
cord-008530-yni0poh9	289	14	a	a	DT
cord-008530-yni0poh9	289	15	variety	variety	NN
cord-008530-yni0poh9	289	16	of	of	IN
cord-008530-yni0poh9	289	17	chemokine	chemokine	NN
cord-008530-yni0poh9	289	18	receptors	receptor	NNS
cord-008530-yni0poh9	289	19	under	under	IN
cord-008530-yni0poh9	289	20	normal	normal	JJ
cord-008530-yni0poh9	289	21	conditions	condition	NNS
cord-008530-yni0poh9	289	22	and	and	CC
cord-008530-yni0poh9	289	23	could	could	MD
cord-008530-yni0poh9	289	24	therefore	therefore	RB
cord-008530-yni0poh9	289	25	facilitate	facilitate	VB
cord-008530-yni0poh9	289	26	a	a	DT
cord-008530-yni0poh9	289	27	direct	direct	JJ
cord-008530-yni0poh9	289	28	interaction	interaction	NN
cord-008530-yni0poh9	289	29	of	of	IN
cord-008530-yni0poh9	289	30	these	these	DT
cord-008530-yni0poh9	289	31	cells	cell	NNS
cord-008530-yni0poh9	289	32	with	with	IN
cord-008530-yni0poh9	289	33	chemokines	chemokine	NNS
cord-008530-yni0poh9	289	34	.	.	.
cord-008530-yni0poh9	290	1	Neurons	neuron	NNS
cord-008530-yni0poh9	290	2	have	have	VBP
cord-008530-yni0poh9	290	3	prominent	prominent	JJ
cord-008530-yni0poh9	290	4	expression	expression	NN
cord-008530-yni0poh9	290	5	of	of	IN
cord-008530-yni0poh9	290	6	many	many	JJ
cord-008530-yni0poh9	290	7	chemokine	chemokine	NN
cord-008530-yni0poh9	290	8	receptors	receptor	NNS
cord-008530-yni0poh9	290	9	including	include	VBG
cord-008530-yni0poh9	290	10	CXCR2	CXCR2	NNS
cord-008530-yni0poh9	290	11	,	,	,
cord-008530-yni0poh9	290	12	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	290	13	,	,	,
cord-008530-yni0poh9	290	14	CCR1	CCR1	NNP
cord-008530-yni0poh9	290	15	,	,	,
cord-008530-yni0poh9	290	16	CCR4	CCR4	NNP
cord-008530-yni0poh9	290	17	,	,	,
cord-008530-yni0poh9	290	18	CCR5	CCR5	NNP
cord-008530-yni0poh9	290	19	,	,	,
cord-008530-yni0poh9	290	20	CCR9/10	ccr9/10	NN
cord-008530-yni0poh9	290	21	,	,	,
cord-008530-yni0poh9	290	22	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	290	23	,	,	,
cord-008530-yni0poh9	290	24	and	and	CC
cord-008530-yni0poh9	290	25	Duffy	Duffy	NNP
cord-008530-yni0poh9	290	26	antigen	antigen	NN
cord-008530-yni0poh9	290	27	-	-	HYPH
cord-008530-yni0poh9	290	28	related	relate	VBN
cord-008530-yni0poh9	290	29	chemokine	chemokine	NN
cord-008530-yni0poh9	290	30	(	(	-LRB-
cord-008530-yni0poh9	290	31	DARC	DARC	NNP
cord-008530-yni0poh9	290	32	)	)	-RRB-
cord-008530-yni0poh9	291	1	(	(	-LRB-
cord-008530-yni0poh9	291	2	Horuk	Horuk	NNP
cord-008530-yni0poh9	291	3	et	et	NNP
cord-008530-yni0poh9	291	4	al	al	NNP
cord-008530-yni0poh9	291	5	.	.	NNP
cord-008530-yni0poh9	291	6	,	,	,
cord-008530-yni0poh9	291	7	1997	1997	CD
cord-008530-yni0poh9	291	8	;	;	:
cord-008530-yni0poh9	291	9	Klein	Klein	NNP
cord-008530-yni0poh9	291	10	et	et	NNP
cord-008530-yni0poh9	291	11	al	al	NNP
cord-008530-yni0poh9	291	12	.	.	NNP
cord-008530-yni0poh9	291	13	,	,	,
cord-008530-yni0poh9	291	14	1999	1999	CD
cord-008530-yni0poh9	292	1	;	;	:
cord-008530-yni0poh9	292	2	Lavi	Lavi	NNP
cord-008530-yni0poh9	292	3	et	et	NNP
cord-008530-yni0poh9	292	4	al	al	NNP
cord-008530-yni0poh9	292	5	.	.	NNP
cord-008530-yni0poh9	292	6	,	,	,
cord-008530-yni0poh9	292	7	1998	1998	CD
cord-008530-yni0poh9	292	8	;	;	:
cord-008530-yni0poh9	292	9	Meucci	Meucci	NNP
cord-008530-yni0poh9	292	10	et	et	NNP
cord-008530-yni0poh9	292	11	al	al	NNP
cord-008530-yni0poh9	292	12	.	.	NNP
cord-008530-yni0poh9	292	13	,	,	,
cord-008530-yni0poh9	292	14	1998	1998	CD
cord-008530-yni0poh9	292	15	;	;	:
cord-008530-yni0poh9	292	16	Sanders	Sanders	NNP
cord-008530-yni0poh9	292	17	et	et	NNP
cord-008530-yni0poh9	292	18	al	al	NNP
cord-008530-yni0poh9	292	19	.	.	NNP
cord-008530-yni0poh9	292	20	,	,	,
cord-008530-yni0poh9	292	21	1998	1998	CD
cord-008530-yni0poh9	292	22	;	;	:
cord-008530-yni0poh9	292	23	Vallat	Vallat	NNP
cord-008530-yni0poh9	292	24	et	et	NNP
cord-008530-yni0poh9	292	25	al	al	NNP
cord-008530-yni0poh9	292	26	.	.	NNP
cord-008530-yni0poh9	292	27	,	,	,
cord-008530-yni0poh9	292	28	1998	1998	CD
cord-008530-yni0poh9	292	29	)	)	-RRB-
cord-008530-yni0poh9	292	30	.	.	.
cord-008530-yni0poh9	293	1	Immunohistochemical	immunohistochemical	JJ
cord-008530-yni0poh9	293	2	staining	staining	NN
cord-008530-yni0poh9	293	3	of	of	IN
cord-008530-yni0poh9	293	4	the	the	DT
cord-008530-yni0poh9	293	5	human	human	JJ
cord-008530-yni0poh9	293	6	brain	brain	NN
cord-008530-yni0poh9	293	7	revealed	reveal	VBD
cord-008530-yni0poh9	293	8	CXCR1	CXCR1	NNP
cord-008530-yni0poh9	293	9	is	be	VBZ
cord-008530-yni0poh9	293	10	not	not	RB
cord-008530-yni0poh9	293	11	detectable	detectable	JJ
cord-008530-yni0poh9	293	12	,	,	,
cord-008530-yni0poh9	293	13	whereas	whereas	IN
cord-008530-yni0poh9	293	14	CXCR2	CXCR2	NNP
cord-008530-yni0poh9	293	15	is	be	VBZ
cord-008530-yni0poh9	293	16	expressed	express	VBN
cord-008530-yni0poh9	293	17	at	at	IN
cord-008530-yni0poh9	293	18	high	high	JJ
cord-008530-yni0poh9	293	19	levels	level	NNS
cord-008530-yni0poh9	293	20	by	by	IN
cord-008530-yni0poh9	293	21	subsets	subset	NNS
cord-008530-yni0poh9	293	22	of	of	IN
cord-008530-yni0poh9	293	23	projection	projection	NN
cord-008530-yni0poh9	293	24	neurons	neuron	NNS
cord-008530-yni0poh9	293	25	in	in	IN
cord-008530-yni0poh9	293	26	different	different	JJ
cord-008530-yni0poh9	293	27	regions	region	NNS
cord-008530-yni0poh9	293	28	of	of	IN
cord-008530-yni0poh9	293	29	the	the	DT
cord-008530-yni0poh9	293	30	brain	brain	NN
cord-008530-yni0poh9	293	31	including	include	VBG
cord-008530-yni0poh9	293	32	the	the	DT
cord-008530-yni0poh9	293	33	hippocampus	hippocampus	NN
cord-008530-yni0poh9	293	34	,	,	,
cord-008530-yni0poh9	293	35	dentate	dentate	NN
cord-008530-yni0poh9	293	36	nucleus	nucleus	NN
cord-008530-yni0poh9	293	37	,	,	,
cord-008530-yni0poh9	293	38	pontine	pontine	JJ
cord-008530-yni0poh9	293	39	nuclei	nucleus	NNS
cord-008530-yni0poh9	293	40	,	,	,
cord-008530-yni0poh9	293	41	locus	locus	NN
cord-008530-yni0poh9	293	42	coeruleus	coeruleu	VBZ
cord-008530-yni0poh9	293	43	,	,	,
cord-008530-yni0poh9	293	44	and	and	CC
cord-008530-yni0poh9	293	45	paraventricular	paraventricular	NNP
cord-008530-yni0poh9	293	46	nucleus	nucleus	NNP
cord-008530-yni0poh9	293	47	,	,	,
cord-008530-yni0poh9	293	48	and	and	CC
cord-008530-yni0poh9	293	49	also	also	RB
cord-008530-yni0poh9	293	50	in	in	IN
cord-008530-yni0poh9	293	51	the	the	DT
cord-008530-yni0poh9	293	52	spinal	spinal	JJ
cord-008530-yni0poh9	293	53	cord	cord	NN
cord-008530-yni0poh9	294	1	(	(	-LRB-
cord-008530-yni0poh9	294	2	Horuk	Horuk	NNP
cord-008530-yni0poh9	294	3	et	et	NNP
cord-008530-yni0poh9	294	4	al	al	NNP
cord-008530-yni0poh9	294	5	.	.	.
cord-008530-yni0poh9	295	1	,	,	,
cord-008530-yni0poh9	295	2	1996	1996	CD
cord-008530-yni0poh9	295	3	;	;	:
cord-008530-yni0poh9	295	4	Horuk	Horuk	NNP
cord-008530-yni0poh9	295	5	et	et	NNP
cord-008530-yni0poh9	295	6	al	al	NNP
cord-008530-yni0poh9	295	7	.	.	NNP
cord-008530-yni0poh9	295	8	,	,	,
cord-008530-yni0poh9	295	9	1997	1997	CD
cord-008530-yni0poh9	295	10	)	)	-RRB-
cord-008530-yni0poh9	295	11	.	.	.
cord-008530-yni0poh9	296	1	DARC	DARC	NNP
cord-008530-yni0poh9	296	2	is	be	VBZ
cord-008530-yni0poh9	296	3	expressed	express	VBN
cord-008530-yni0poh9	296	4	by	by	IN
cord-008530-yni0poh9	296	5	subsets	subset	NNS
cord-008530-yni0poh9	296	6	of	of	IN
cord-008530-yni0poh9	296	7	endothelial	endothelial	JJ
cord-008530-yni0poh9	296	8	cells	cell	NNS
cord-008530-yni0poh9	296	9	and	and	CC
cord-008530-yni0poh9	296	10	Purkinje	Purkinje	NNP
cord-008530-yni0poh9	296	11	cells	cell	NNS
cord-008530-yni0poh9	296	12	in	in	IN
cord-008530-yni0poh9	296	13	the	the	DT
cord-008530-yni0poh9	296	14	cerebellum	cerebellum	NN
cord-008530-yni0poh9	296	15	,	,	,
cord-008530-yni0poh9	296	16	suggesting	suggest	VBG
cord-008530-yni0poh9	296	17	that	that	IN
cord-008530-yni0poh9	296	18	this	this	DT
cord-008530-yni0poh9	296	19	enigmatic	enigmatic	JJ
cord-008530-yni0poh9	296	20	receptor	receptor	NN
cord-008530-yni0poh9	296	21	that	that	WDT
cord-008530-yni0poh9	296	22	lacks	lack	VBZ
cord-008530-yni0poh9	296	23	signaling	signal	VBG
cord-008530-yni0poh9	296	24	function	function	NN
cord-008530-yni0poh9	296	25	may	may	MD
cord-008530-yni0poh9	296	26	have	have	VB
cord-008530-yni0poh9	296	27	multiple	multiple	JJ
cord-008530-yni0poh9	296	28	roles	role	NNS
cord-008530-yni0poh9	296	29	in	in	IN
cord-008530-yni0poh9	296	30	normal	normal	JJ
cord-008530-yni0poh9	296	31	and	and	CC
cord-008530-yni0poh9	296	32	pathological	pathological	JJ
cord-008530-yni0poh9	296	33	physiology	physiology	NN
cord-008530-yni0poh9	296	34	,	,	,
cord-008530-yni0poh9	296	35	perhaps	perhaps	RB
cord-008530-yni0poh9	296	36	as	as	IN
cord-008530-yni0poh9	296	37	a	a	DT
cord-008530-yni0poh9	296	38	chemokine	chemokine	NN
cord-008530-yni0poh9	296	39	clearance	clearance	NN
cord-008530-yni0poh9	296	40	receptor	receptor	NN
cord-008530-yni0poh9	296	41	(	(	-LRB-
cord-008530-yni0poh9	296	42	Horuk	Horuk	NNP
cord-008530-yni0poh9	296	43	et	et	NNP
cord-008530-yni0poh9	296	44	al	al	NNP
cord-008530-yni0poh9	296	45	.	.	NNP
cord-008530-yni0poh9	296	46	,	,	,
cord-008530-yni0poh9	296	47	1996	1996	CD
cord-008530-yni0poh9	296	48	;	;	:
cord-008530-yni0poh9	296	49	Horuk	Horuk	NNP
cord-008530-yni0poh9	296	50	et	et	NNP
cord-008530-yni0poh9	296	51	al	al	NNP
cord-008530-yni0poh9	296	52	.	.	NNP
cord-008530-yni0poh9	296	53	,	,	,
cord-008530-yni0poh9	296	54	1997	1997	CD
cord-008530-yni0poh9	296	55	)	)	-RRB-
cord-008530-yni0poh9	296	56	.	.	.
cord-008530-yni0poh9	297	1	Functional	functional	JJ
cord-008530-yni0poh9	297	2	CCR3	CCR3	NNP
cord-008530-yni0poh9	297	3	,	,	,
cord-008530-yni0poh9	297	4	CCR5	CCR5	NNP
cord-008530-yni0poh9	297	5	,	,	,
cord-008530-yni0poh9	297	6	and	and	CC
cord-008530-yni0poh9	297	7	CXCR4	cxcr4	NN
cord-008530-yni0poh9	297	8	receptors	receptor	NNS
cord-008530-yni0poh9	297	9	,	,	,
cord-008530-yni0poh9	297	10	with	with	IN
cord-008530-yni0poh9	297	11	different	different	JJ
cord-008530-yni0poh9	297	12	patterns	pattern	NNS
cord-008530-yni0poh9	297	13	of	of	IN
cord-008530-yni0poh9	297	14	distribution	distribution	NN
cord-008530-yni0poh9	297	15	,	,	,
cord-008530-yni0poh9	297	16	were	be	VBD
cord-008530-yni0poh9	297	17	demonstrated	demonstrate	VBN
cord-008530-yni0poh9	297	18	on	on	IN
cord-008530-yni0poh9	297	19	cultured	cultured	JJ
cord-008530-yni0poh9	297	20	fetal	fetal	JJ
cord-008530-yni0poh9	297	21	human	human	JJ
cord-008530-yni0poh9	297	22	and	and	CC
cord-008530-yni0poh9	297	23	macaque	macaque	NN
cord-008530-yni0poh9	297	24	neurons	neuron	NNS
cord-008530-yni0poh9	297	25	(	(	-LRB-
cord-008530-yni0poh9	297	26	Klein	Klein	NNP
cord-008530-yni0poh9	297	27	et	et	NNP
cord-008530-yni0poh9	297	28	al	al	NNP
cord-008530-yni0poh9	297	29	.	.	NNP
cord-008530-yni0poh9	297	30	,	,	,
cord-008530-yni0poh9	297	31	1999	1999	CD
cord-008530-yni0poh9	297	32	)	)	-RRB-
cord-008530-yni0poh9	297	33	.	.	.
cord-008530-yni0poh9	298	1	Expression	expression	NN
cord-008530-yni0poh9	298	2	of	of	IN
cord-008530-yni0poh9	298	3	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	298	4	has	have	VBZ
cord-008530-yni0poh9	298	5	also	also	RB
cord-008530-yni0poh9	298	6	been	be	VBN
cord-008530-yni0poh9	298	7	detected	detect	VBN
cord-008530-yni0poh9	298	8	by	by	IN
cord-008530-yni0poh9	298	9	immunohistochemical	immunohistochemical	JJ
cord-008530-yni0poh9	298	10	staining	stain	VBG
cord-008530-yni0poh9	298	11	on	on	IN
cord-008530-yni0poh9	298	12	subpopulations	subpopulation	NNS
cord-008530-yni0poh9	298	13	of	of	IN
cord-008530-yni0poh9	298	14	neurons	neuron	NNS
cord-008530-yni0poh9	298	15	in	in	IN
cord-008530-yni0poh9	298	16	the	the	DT
cord-008530-yni0poh9	298	17	normal	normal	JJ
cord-008530-yni0poh9	298	18	adult	adult	NN
cord-008530-yni0poh9	298	19	brain	brain	NN
cord-008530-yni0poh9	298	20	(	(	-LRB-
cord-008530-yni0poh9	298	21	Lavi	Lavi	NNP
cord-008530-yni0poh9	298	22	et	et	FW
cord-008530-yni0poh9	298	23	al	al	NNP
cord-008530-yni0poh9	298	24	.	.	.
cord-008530-yni0poh9	299	1	,	,	,
cord-008530-yni0poh9	299	2	1997	1997	CD
cord-008530-yni0poh9	299	3	;	;	:
cord-008530-yni0poh9	299	4	Sanders	Sanders	NNP
cord-008530-yni0poh9	299	5	et	et	NNP
cord-008530-yni0poh9	299	6	al	al	NNP
cord-008530-yni0poh9	299	7	.	.	NNP
cord-008530-yni0poh9	299	8	,	,	,
cord-008530-yni0poh9	299	9	1998	1998	CD
cord-008530-yni0poh9	299	10	;	;	:
cord-008530-yni0poh9	299	11	Vallat	Vallat	NNP
cord-008530-yni0poh9	299	12	et	et	NNP
cord-008530-yni0poh9	299	13	al	al	NNP
cord-008530-yni0poh9	299	14	.	.	NNP
cord-008530-yni0poh9	299	15	,	,	,
cord-008530-yni0poh9	299	16	1998	1998	CD
cord-008530-yni0poh9	299	17	)	)	-RRB-
cord-008530-yni0poh9	299	18	,	,	,
cord-008530-yni0poh9	299	19	while	while	IN
cord-008530-yni0poh9	299	20	in	in	IN
cord-008530-yni0poh9	299	21	the	the	DT
cord-008530-yni0poh9	299	22	rat	rat	NN
cord-008530-yni0poh9	299	23	,	,	,
cord-008530-yni0poh9	299	24	levels	level	NNS
cord-008530-yni0poh9	299	25	of	of	IN
cord-008530-yni0poh9	299	26	the	the	DT
cord-008530-yni0poh9	299	27	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	299	28	receptor	receptor	NN
cord-008530-yni0poh9	299	29	RNA	RNA	NNP
cord-008530-yni0poh9	299	30	are	be	VBP
cord-008530-yni0poh9	299	31	higher	high	JJR
cord-008530-yni0poh9	299	32	on	on	IN
cord-008530-yni0poh9	299	33	specific	specific	JJ
cord-008530-yni0poh9	299	34	neurons	neuron	NNS
cord-008530-yni0poh9	299	35	,	,	,
cord-008530-yni0poh9	299	36	which	which	WDT
cord-008530-yni0poh9	299	37	include	include	VBP
cord-008530-yni0poh9	299	38	cerebellar	cerebellar	JJ
cord-008530-yni0poh9	299	39	Purkinje	Purkinje	NNP
cord-008530-yni0poh9	299	40	cells	cell	NNS
cord-008530-yni0poh9	299	41	,	,	,
cord-008530-yni0poh9	299	42	hippocampal	hippocampal	JJ
cord-008530-yni0poh9	299	43	hilar	hilar	JJ
cord-008530-yni0poh9	299	44	neurons	neuron	NNS
cord-008530-yni0poh9	299	45	,	,	,
cord-008530-yni0poh9	299	46	and	and	CC
cord-008530-yni0poh9	299	47	cerebral	cerebral	JJ
cord-008530-yni0poh9	299	48	cortical	cortical	JJ
cord-008530-yni0poh9	299	49	neurons	neuron	NNS
cord-008530-yni0poh9	300	1	(	(	-LRB-
cord-008530-yni0poh9	300	2	Wong	Wong	NNP
cord-008530-yni0poh9	300	3	et	et	NNP
cord-008530-yni0poh9	300	4	al	al	NNP
cord-008530-yni0poh9	300	5	.	.	NNP
cord-008530-yni0poh9	300	6	,	,	,
cord-008530-yni0poh9	300	7	1996	1996	CD
cord-008530-yni0poh9	300	8	)	)	-RRB-
cord-008530-yni0poh9	300	9	.	.	.
cord-008530-yni0poh9	301	1	A	a	DT
cord-008530-yni0poh9	301	2	clear	clear	JJ
cord-008530-yni0poh9	301	3	theme	theme	NN
cord-008530-yni0poh9	301	4	emerging	emerge	VBG
cord-008530-yni0poh9	301	5	from	from	IN
cord-008530-yni0poh9	301	6	all	all	PDT
cord-008530-yni0poh9	301	7	these	these	DT
cord-008530-yni0poh9	301	8	studies	study	NNS
cord-008530-yni0poh9	301	9	is	be	VBZ
cord-008530-yni0poh9	301	10	that	that	IN
cord-008530-yni0poh9	301	11	neurons	neuron	NNS
cord-008530-yni0poh9	301	12	express	express	VBP
cord-008530-yni0poh9	301	13	a	a	DT
cord-008530-yni0poh9	301	14	variety	variety	NN
cord-008530-yni0poh9	301	15	of	of	IN
cord-008530-yni0poh9	301	16	chemokine	chemokine	NN
cord-008530-yni0poh9	301	17	receptors	receptor	NNS
cord-008530-yni0poh9	301	18	and	and	CC
cord-008530-yni0poh9	301	19	that	that	IN
cord-008530-yni0poh9	301	20	this	this	DT
cord-008530-yni0poh9	301	21	expression	expression	NN
cord-008530-yni0poh9	301	22	in	in	IN
cord-008530-yni0poh9	301	23	the	the	DT
cord-008530-yni0poh9	301	24	CNS	CNS	NNP
cord-008530-yni0poh9	301	25	exhibits	exhibit	NNS
cord-008530-yni0poh9	301	26	marked	mark	VBN
cord-008530-yni0poh9	301	27	regional	regional	JJ
cord-008530-yni0poh9	301	28	and	and	CC
cord-008530-yni0poh9	301	29	cellular	cellular	JJ
cord-008530-yni0poh9	301	30	diversity	diversity	NN
cord-008530-yni0poh9	301	31	,	,	,
cord-008530-yni0poh9	301	32	suggesting	suggest	VBG
cord-008530-yni0poh9	301	33	that	that	IN
cord-008530-yni0poh9	301	34	chemokines	chemokine	NNS
cord-008530-yni0poh9	301	35	could	could	MD
cord-008530-yni0poh9	301	36	have	have	VB
cord-008530-yni0poh9	301	37	differential	differential	JJ
cord-008530-yni0poh9	301	38	effects	effect	NNS
cord-008530-yni0poh9	301	39	on	on	IN
cord-008530-yni0poh9	301	40	different	different	JJ
cord-008530-yni0poh9	301	41	neurons	neuron	NNS
cord-008530-yni0poh9	301	42	.	.	.
cord-008530-yni0poh9	302	1	Other	other	JJ
cord-008530-yni0poh9	302	2	than	than	IN
cord-008530-yni0poh9	302	3	neurons	neuron	NNS
cord-008530-yni0poh9	302	4	,	,	,
cord-008530-yni0poh9	302	5	glial	glial	JJ
cord-008530-yni0poh9	302	6	cells	cell	NNS
cord-008530-yni0poh9	302	7	also	also	RB
cord-008530-yni0poh9	302	8	express	express	VBP
cord-008530-yni0poh9	302	9	a	a	DT
cord-008530-yni0poh9	302	10	variety	variety	NN
cord-008530-yni0poh9	302	11	of	of	IN
cord-008530-yni0poh9	302	12	chemokine	chemokine	NN
cord-008530-yni0poh9	302	13	receptors	receptor	NNS
cord-008530-yni0poh9	302	14	.	.	.
cord-008530-yni0poh9	303	1	The	the	DT
cord-008530-yni0poh9	303	2	fractalkine	fractalkine	JJ
cord-008530-yni0poh9	303	3	receptor	receptor	NN
cord-008530-yni0poh9	303	4	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	303	5	is	be	VBZ
cord-008530-yni0poh9	303	6	found	find	VBN
cord-008530-yni0poh9	303	7	at	at	IN
cord-008530-yni0poh9	303	8	high	high	JJ
cord-008530-yni0poh9	303	9	levels	level	NNS
cord-008530-yni0poh9	303	10	in	in	IN
cord-008530-yni0poh9	303	11	rodent	rodent	NN
cord-008530-yni0poh9	303	12	and	and	CC
cord-008530-yni0poh9	303	13	human	human	JJ
cord-008530-yni0poh9	303	14	brain	brain	NN
cord-008530-yni0poh9	303	15	and	and	CC
cord-008530-yni0poh9	303	16	shows	show	VBZ
cord-008530-yni0poh9	303	17	strong	strong	JJ
cord-008530-yni0poh9	303	18	localization	localization	NN
cord-008530-yni0poh9	303	19	to	to	IN
cord-008530-yni0poh9	303	20	microglia	microglia	NNP
cord-008530-yni0poh9	303	21	(	(	-LRB-
cord-008530-yni0poh9	303	22	Combadiere	Combadiere	NNP
cord-008530-yni0poh9	303	23	et	et	FW
cord-008530-yni0poh9	303	24	al	al	NNP
cord-008530-yni0poh9	303	25	.	.	NNP
cord-008530-yni0poh9	303	26	,	,	,
cord-008530-yni0poh9	303	27	1998	1998	CD
cord-008530-yni0poh9	303	28	;	;	:
cord-008530-yni0poh9	304	1	Harrison	Harrison	NNP
cord-008530-yni0poh9	304	2	et	et	NNP
cord-008530-yni0poh9	304	3	al	al	NNP
cord-008530-yni0poh9	304	4	.	.	.
cord-008530-yni0poh9	305	1	,	,	,
cord-008530-yni0poh9	305	2	1998	1998	CD
cord-008530-yni0poh9	305	3	;	;	:
cord-008530-yni0poh9	305	4	Imai	Imai	NNP
cord-008530-yni0poh9	305	5	et	et	NNP
cord-008530-yni0poh9	305	6	al	al	NNP
cord-008530-yni0poh9	305	7	.	.	NNP
cord-008530-yni0poh9	305	8	,	,	,
cord-008530-yni0poh9	305	9	1997	1997	CD
cord-008530-yni0poh9	305	10	)	)	-RRB-
cord-008530-yni0poh9	305	11	.	.	.
cord-008530-yni0poh9	306	1	The	the	DT
cord-008530-yni0poh9	306	2	fact	fact	NN
cord-008530-yni0poh9	306	3	that	that	IN
cord-008530-yni0poh9	306	4	fractalkine	fractalkine	NN
cord-008530-yni0poh9	306	5	is	be	VBZ
cord-008530-yni0poh9	306	6	expressed	express	VBN
cord-008530-yni0poh9	306	7	by	by	IN
cord-008530-yni0poh9	306	8	neurons	neuron	NNS
cord-008530-yni0poh9	306	9	(	(	-LRB-
cord-008530-yni0poh9	306	10	as	as	IN
cord-008530-yni0poh9	306	11	noted	note	VBN
cord-008530-yni0poh9	306	12	above	above	IN
cord-008530-yni0poh9	306	13	)	)	-RRB-
cord-008530-yni0poh9	306	14	,	,	,
cord-008530-yni0poh9	306	15	and	and	CC
cord-008530-yni0poh9	306	16	its	-PRON-	PRP$
cord-008530-yni0poh9	306	17	receptor	receptor	NN
cord-008530-yni0poh9	306	18	by	by	IN
cord-008530-yni0poh9	306	19	microglia	microglia	NNP
cord-008530-yni0poh9	306	20	,	,	,
cord-008530-yni0poh9	306	21	suggests	suggest	VBZ
cord-008530-yni0poh9	306	22	a	a	DT
cord-008530-yni0poh9	306	23	possible	possible	JJ
cord-008530-yni0poh9	306	24	important	important	JJ
cord-008530-yni0poh9	306	25	role	role	NN
cord-008530-yni0poh9	306	26	for	for	IN
cord-008530-yni0poh9	306	27	this	this	DT
cord-008530-yni0poh9	306	28	chemokine	chemokine	NN
cord-008530-yni0poh9	306	29	and	and	CC
cord-008530-yni0poh9	306	30	its	-PRON-	PRP$
cord-008530-yni0poh9	306	31	receptor	receptor	NN
cord-008530-yni0poh9	306	32	in	in	IN
cord-008530-yni0poh9	306	33	communication	communication	NN
cord-008530-yni0poh9	306	34	between	between	IN
cord-008530-yni0poh9	306	35	neurons	neuron	NNS
cord-008530-yni0poh9	306	36	and	and	CC
cord-008530-yni0poh9	306	37	microglia	microglia	NNS
cord-008530-yni0poh9	306	38	.	.	.
cord-008530-yni0poh9	307	1	A	a	DT
cord-008530-yni0poh9	307	2	similar	similar	JJ
cord-008530-yni0poh9	307	3	scenario	scenario	NN
cord-008530-yni0poh9	307	4	may	may	MD
cord-008530-yni0poh9	307	5	follow	follow	VB
cord-008530-yni0poh9	307	6	with	with	IN
cord-008530-yni0poh9	307	7	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	307	8	,	,	,
cord-008530-yni0poh9	307	9	whose	whose	WP$
cord-008530-yni0poh9	307	10	receptor	receptor	NN
cord-008530-yni0poh9	307	11	,	,	,
cord-008530-yni0poh9	307	12	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	307	13	,	,	,
cord-008530-yni0poh9	307	14	in	in	IN
cord-008530-yni0poh9	307	15	addition	addition	NN
cord-008530-yni0poh9	307	16	to	to	IN
cord-008530-yni0poh9	307	17	expression	expression	NN
cord-008530-yni0poh9	307	18	by	by	IN
cord-008530-yni0poh9	307	19	neurons	neuron	NNS
cord-008530-yni0poh9	307	20	,	,	,
cord-008530-yni0poh9	307	21	is	be	VBZ
cord-008530-yni0poh9	307	22	found	find	VBN
cord-008530-yni0poh9	307	23	on	on	IN
cord-008530-yni0poh9	307	24	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	307	25	(	(	-LRB-
cord-008530-yni0poh9	307	26	Heesen	Heesen	NNP
cord-008530-yni0poh9	307	27	et	et	NNP
cord-008530-yni0poh9	307	28	al	al	NNP
cord-008530-yni0poh9	307	29	.	.	NNP
cord-008530-yni0poh9	307	30	,	,	,
cord-008530-yni0poh9	307	31	1996	1996	CD
cord-008530-yni0poh9	307	32	)	)	-RRB-
cord-008530-yni0poh9	307	33	and	and	CC
cord-008530-yni0poh9	307	34	on	on	IN
cord-008530-yni0poh9	307	35	microglial	microglial	JJ
cord-008530-yni0poh9	307	36	cells	cell	NNS
cord-008530-yni0poh9	307	37	(	(	-LRB-
cord-008530-yni0poh9	308	1	Tanabe	Tanabe	NNP
cord-008530-yni0poh9	308	2	et	et	NNP
cord-008530-yni0poh9	308	3	al	al	NNP
cord-008530-yni0poh9	308	4	.	.	NNP
cord-008530-yni0poh9	308	5	,	,	,
cord-008530-yni0poh9	308	6	1997b	1997b	CD
cord-008530-yni0poh9	308	7	)	)	-RRB-
cord-008530-yni0poh9	308	8	.	.	.
cord-008530-yni0poh9	309	1	Finally	finally	RB
cord-008530-yni0poh9	309	2	,	,	,
cord-008530-yni0poh9	309	3	the	the	DT
cord-008530-yni0poh9	309	4	CC	CC	NNP
cord-008530-yni0poh9	309	5	chemokine	chemokine	NN
cord-008530-yni0poh9	309	6	receptors	receptor	NNS
cord-008530-yni0poh9	309	7	CCR1	CCR1	NNP
cord-008530-yni0poh9	309	8	,	,	,
cord-008530-yni0poh9	309	9	CCR5	CCR5	NNP
cord-008530-yni0poh9	309	10	,	,	,
cord-008530-yni0poh9	309	11	and	and	CC
cord-008530-yni0poh9	309	12	CCR3	CCR3	NNP
cord-008530-yni0poh9	309	13	have	have	VBP
cord-008530-yni0poh9	309	14	been	be	VBN
cord-008530-yni0poh9	309	15	shown	show	VBN
cord-008530-yni0poh9	309	16	to	to	TO
cord-008530-yni0poh9	309	17	be	be	VB
cord-008530-yni0poh9	309	18	expressed	express	VBN
cord-008530-yni0poh9	309	19	by	by	IN
cord-008530-yni0poh9	309	20	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	309	21	and/or	and/or	CC
cord-008530-yni0poh9	309	22	microglial	microglial	JJ
cord-008530-yni0poh9	309	23	cells	cell	NNS
cord-008530-yni0poh9	309	24	both	both	DT
cord-008530-yni0poh9	309	25	in	in	IN
cord-008530-yni0poh9	309	26	vitro	vitro	FW
cord-008530-yni0poh9	309	27	and	and	CC
cord-008530-yni0poh9	309	28	in	in	IN
cord-008530-yni0poh9	309	29	vivo	vivo	NN
cord-008530-yni0poh9	310	1	(	(	-LRB-
cord-008530-yni0poh9	310	2	Boddeke	Boddeke	NNP
cord-008530-yni0poh9	310	3	et	et	FW
cord-008530-yni0poh9	310	4	al	al	NNP
cord-008530-yni0poh9	310	5	.	.	NNP
cord-008530-yni0poh9	310	6	,	,	,
cord-008530-yni0poh9	310	7	1999	1999	CD
cord-008530-yni0poh9	311	1	;	;	:
cord-008530-yni0poh9	311	2	He	-PRON-	PRP
cord-008530-yni0poh9	311	3	et	et	FW
cord-008530-yni0poh9	311	4	al	al	NNP
cord-008530-yni0poh9	311	5	.	.	NNP
cord-008530-yni0poh9	311	6	,	,	,
cord-008530-yni0poh9	311	7	1997	1997	CD
cord-008530-yni0poh9	311	8	;	;	:
cord-008530-yni0poh9	311	9	Lavi	Lavi	NNP
cord-008530-yni0poh9	311	10	et	et	NNP
cord-008530-yni0poh9	311	11	al	al	NNP
cord-008530-yni0poh9	311	12	.	.	NNP
cord-008530-yni0poh9	311	13	,	,	,
cord-008530-yni0poh9	311	14	1998	1998	CD
cord-008530-yni0poh9	311	15	;	;	:
cord-008530-yni0poh9	312	1	Tanabe	Tanabe	NNP
cord-008530-yni0poh9	312	2	et	et	NNP
cord-008530-yni0poh9	312	3	al	al	NNP
cord-008530-yni0poh9	312	4	.	.	.
cord-008530-yni0poh9	313	1	,	,	,
cord-008530-yni0poh9	313	2	1997a	1997a	CD
cord-008530-yni0poh9	313	3	;	;	:
cord-008530-yni0poh9	313	4	Vallat	Vallat	NNP
cord-008530-yni0poh9	313	5	et	et	NNP
cord-008530-yni0poh9	313	6	al	al	NNP
cord-008530-yni0poh9	313	7	.	.	NNP
cord-008530-yni0poh9	313	8	,	,	,
cord-008530-yni0poh9	313	9	1998	1998	CD
cord-008530-yni0poh9	313	10	;	;	:
cord-008530-yni0poh9	313	11	Westmoreland	Westmoreland	NNP
cord-008530-yni0poh9	313	12	et	et	NNP
cord-008530-yni0poh9	313	13	al	al	NNP
cord-008530-yni0poh9	313	14	.	.	NNP
cord-008530-yni0poh9	313	15	,	,	,
cord-008530-yni0poh9	313	16	1998	1998	CD
cord-008530-yni0poh9	314	1	;	;	:
cord-008530-yni0poh9	314	2	Xia	Xia	NNP
cord-008530-yni0poh9	314	3	et	et	NNP
cord-008530-yni0poh9	314	4	al	al	NNP
cord-008530-yni0poh9	314	5	.	.	NNP
cord-008530-yni0poh9	314	6	,	,	,
cord-008530-yni0poh9	314	7	1998	1998	CD
cord-008530-yni0poh9	314	8	)	)	-RRB-
cord-008530-yni0poh9	314	9	.	.	.
cord-008530-yni0poh9	315	1	The	the	DT
cord-008530-yni0poh9	315	2	expression	expression	NN
cord-008530-yni0poh9	315	3	of	of	IN
cord-008530-yni0poh9	315	4	many	many	JJ
cord-008530-yni0poh9	315	5	of	of	IN
cord-008530-yni0poh9	315	6	these	these	DT
cord-008530-yni0poh9	315	7	chemokine	chemokine	NN
cord-008530-yni0poh9	315	8	receptors	receptor	NNS
cord-008530-yni0poh9	315	9	in	in	IN
cord-008530-yni0poh9	315	10	the	the	DT
cord-008530-yni0poh9	315	11	CNS	CNS	NNP
cord-008530-yni0poh9	315	12	is	be	VBZ
cord-008530-yni0poh9	315	13	not	not	RB
cord-008530-yni0poh9	315	14	static	static	JJ
cord-008530-yni0poh9	315	15	and	and	CC
cord-008530-yni0poh9	315	16	can	can	MD
cord-008530-yni0poh9	315	17	be	be	VB
cord-008530-yni0poh9	315	18	dynamically	dynamically	RB
cord-008530-yni0poh9	315	19	regulated	regulate	VBN
cord-008530-yni0poh9	315	20	by	by	IN
cord-008530-yni0poh9	315	21	various	various	JJ
cord-008530-yni0poh9	315	22	stimuli	stimulus	NNS
cord-008530-yni0poh9	315	23	.	.	.
cord-008530-yni0poh9	316	1	For	for	IN
cord-008530-yni0poh9	316	2	example	example	NN
cord-008530-yni0poh9	316	3	,	,	,
cord-008530-yni0poh9	316	4	in	in	IN
cord-008530-yni0poh9	316	5	a	a	DT
cord-008530-yni0poh9	316	6	model	model	NN
cord-008530-yni0poh9	316	7	of	of	IN
cord-008530-yni0poh9	316	8	excitotoxic	excitotoxic	JJ
cord-008530-yni0poh9	316	9	brain	brain	NN
cord-008530-yni0poh9	316	10	injury	injury	NN
cord-008530-yni0poh9	316	11	induced	induce	VBN
cord-008530-yni0poh9	316	12	by	by	IN
cord-008530-yni0poh9	316	13	intracerebral	intracerebral	JJ
cord-008530-yni0poh9	316	14	injection	injection	NN
cord-008530-yni0poh9	316	15	of	of	IN
cord-008530-yni0poh9	316	16	NMDA	NMDA	NNP
cord-008530-yni0poh9	316	17	in	in	IN
cord-008530-yni0poh9	316	18	the	the	DT
cord-008530-yni0poh9	316	19	rat	rat	NN
cord-008530-yni0poh9	316	20	,	,	,
cord-008530-yni0poh9	316	21	marked	mark	VBN
cord-008530-yni0poh9	316	22	upregulation	upregulation	NN
cord-008530-yni0poh9	316	23	of	of	IN
cord-008530-yni0poh9	316	24	CCR5	ccr5	JJ
cord-008530-yni0poh9	316	25	expression	expression	NN
cord-008530-yni0poh9	316	26	was	be	VBD
cord-008530-yni0poh9	316	27	observed	observe	VBN
cord-008530-yni0poh9	316	28	by	by	IN
cord-008530-yni0poh9	316	29	microglia	microglia	NNS
cord-008530-yni0poh9	316	30	and	and	CC
cord-008530-yni0poh9	316	31	neurons	neuron	NNS
cord-008530-yni0poh9	317	1	(	(	-LRB-
cord-008530-yni0poh9	317	2	Galasso	Galasso	NNP
cord-008530-yni0poh9	317	3	et	et	NNP
cord-008530-yni0poh9	317	4	al	al	NNP
cord-008530-yni0poh9	317	5	.	.	NNP
cord-008530-yni0poh9	317	6	,	,	,
cord-008530-yni0poh9	317	7	1998	1998	CD
cord-008530-yni0poh9	317	8	)	)	-RRB-
cord-008530-yni0poh9	317	9	.	.	.
cord-008530-yni0poh9	318	1	In	in	IN
cord-008530-yni0poh9	318	2	brain	brain	NN
cord-008530-yni0poh9	318	3	from	from	IN
cord-008530-yni0poh9	318	4	Alzheimer	Alzheimer	NNP
cord-008530-yni0poh9	318	5	's	's	POS
cord-008530-yni0poh9	318	6	cases	case	NNS
cord-008530-yni0poh9	318	7	,	,	,
cord-008530-yni0poh9	318	8	plaque	plaque	NN
cord-008530-yni0poh9	318	9	-	-	HYPH
cord-008530-yni0poh9	318	10	associated	associate	VBN
cord-008530-yni0poh9	318	11	reactive	reactive	JJ
cord-008530-yni0poh9	318	12	microglia	microglia	NN
cord-008530-yni0poh9	318	13	also	also	RB
cord-008530-yni0poh9	318	14	show	show	VBP
cord-008530-yni0poh9	318	15	increased	increase	VBD
cord-008530-yni0poh9	318	16	CCR5	CCR5	NNP
cord-008530-yni0poh9	318	17	expression	expression	NN
cord-008530-yni0poh9	318	18	.	.	.
cord-008530-yni0poh9	319	1	Expression	expression	NN
cord-008530-yni0poh9	319	2	of	of	IN
cord-008530-yni0poh9	319	3	the	the	DT
cord-008530-yni0poh9	319	4	fractalkine	fractalkine	JJ
cord-008530-yni0poh9	319	5	receptor	receptor	NN
cord-008530-yni0poh9	319	6	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	319	7	is	be	VBZ
cord-008530-yni0poh9	319	8	increased	increase	VBN
cord-008530-yni0poh9	319	9	on	on	IN
cord-008530-yni0poh9	319	10	perineural	perineural	JJ
cord-008530-yni0poh9	319	11	microglia	microglia	NNP
cord-008530-yni0poh9	319	12	following	follow	VBG
cord-008530-yni0poh9	319	13	facial	facial	JJ
cord-008530-yni0poh9	319	14	nerve	nerve	NN
cord-008530-yni0poh9	319	15	axotomy	axotomy	.
cord-008530-yni0poh9	319	16	in	in	IN
cord-008530-yni0poh9	319	17	the	the	DT
cord-008530-yni0poh9	319	18	rat	rat	NN
cord-008530-yni0poh9	319	19	.	.	.
cord-008530-yni0poh9	320	1	Boddeke	Boddeke	NNP
cord-008530-yni0poh9	320	2	et	et	FW
cord-008530-yni0poh9	320	3	al	al	NNP
cord-008530-yni0poh9	320	4	.	.	.
cord-008530-yni0poh9	321	1	,	,	,
cord-008530-yni0poh9	321	2	have	have	VBP
cord-008530-yni0poh9	321	3	shown	show	VBN
cord-008530-yni0poh9	321	4	,	,	,
cord-008530-yni0poh9	321	5	by	by	IN
cord-008530-yni0poh9	321	6	RT	RT	NNP
cord-008530-yni0poh9	321	7	-	-	HYPH
cord-008530-yni0poh9	321	8	PCR	PCR	NNP
cord-008530-yni0poh9	321	9	(	(	-LRB-
cord-008530-yni0poh9	321	10	reverse	reverse	JJ
cord-008530-yni0poh9	321	11	transcription	transcription	NN
cord-008530-yni0poh9	321	12	-	-	HYPH
cord-008530-yni0poh9	321	13	polymerase	polymerase	NN
cord-008530-yni0poh9	321	14	chain	chain	NN
cord-008530-yni0poh9	321	15	rear	rear	NN
cord-008530-yni0poh9	321	16	)	)	-RRB-
cord-008530-yni0poh9	321	17	analysis	analysis	NN
cord-008530-yni0poh9	321	18	,	,	,
cord-008530-yni0poh9	321	19	that	that	IN
cord-008530-yni0poh9	321	20	CCR1	CCR1	NNP
cord-008530-yni0poh9	321	21	,	,	,
cord-008530-yni0poh9	321	22	CCR2	CCR2	NNP
cord-008530-yni0poh9	321	23	,	,	,
cord-008530-yni0poh9	321	24	and	and	CC
cord-008530-yni0poh9	321	25	CCR5	ccr5	JJ
cord-008530-yni0poh9	321	26	expression	expression	NN
cord-008530-yni0poh9	321	27	in	in	IN
cord-008530-yni0poh9	321	28	cultured	cultured	JJ
cord-008530-yni0poh9	321	29	rat	rat	NN
cord-008530-yni0poh9	321	30	microglial	microglial	JJ
cord-008530-yni0poh9	321	31	cells	cell	NNS
cord-008530-yni0poh9	321	32	is	be	VBZ
cord-008530-yni0poh9	321	33	significantly	significantly	RB
cord-008530-yni0poh9	321	34	upregulated	upregulate	VBN
cord-008530-yni0poh9	321	35	after	after	IN
cord-008530-yni0poh9	321	36	LPS	LPS	NNP
cord-008530-yni0poh9	321	37	treatment	treatment	NN
cord-008530-yni0poh9	321	38	(	(	-LRB-
cord-008530-yni0poh9	321	39	Boddeke	Boddeke	NNP
cord-008530-yni0poh9	321	40	et	et	FW
cord-008530-yni0poh9	321	41	al	al	NNP
cord-008530-yni0poh9	321	42	.	.	NNP
cord-008530-yni0poh9	321	43	,	,	,
cord-008530-yni0poh9	321	44	1999	1999	CD
cord-008530-yni0poh9	321	45	;	;	:
cord-008530-yni0poh9	321	46	Spleiss	Spleiss	NNP
cord-008530-yni0poh9	321	47	et	et	NNP
cord-008530-yni0poh9	321	48	al	al	NNP
cord-008530-yni0poh9	321	49	.	.	NNP
cord-008530-yni0poh9	321	50	,	,	,
cord-008530-yni0poh9	321	51	1998	1998	CD
cord-008530-yni0poh9	321	52	)	)	-RRB-
cord-008530-yni0poh9	321	53	.	.	.
cord-008530-yni0poh9	322	1	The	the	DT
cord-008530-yni0poh9	322	2	pathophysiological	pathophysiological	JJ
cord-008530-yni0poh9	322	3	significance	significance	NN
cord-008530-yni0poh9	322	4	of	of	IN
cord-008530-yni0poh9	322	5	altered	alter	VBN
cord-008530-yni0poh9	322	6	CNS	CNS	NNP
cord-008530-yni0poh9	322	7	chemokine	chemokine	NN
cord-008530-yni0poh9	322	8	receptor	receptor	NN
cord-008530-yni0poh9	322	9	expression	expression	NN
cord-008530-yni0poh9	322	10	in	in	IN
cord-008530-yni0poh9	322	11	disease	disease	NN
cord-008530-yni0poh9	322	12	states	state	NNS
cord-008530-yni0poh9	322	13	remains	remain	VBZ
cord-008530-yni0poh9	322	14	to	to	TO
cord-008530-yni0poh9	322	15	be	be	VB
cord-008530-yni0poh9	322	16	determined	determine	VBN
cord-008530-yni0poh9	322	17	.	.	.
cord-008530-yni0poh9	323	1	However	however	RB
cord-008530-yni0poh9	323	2	,	,	,
cord-008530-yni0poh9	323	3	it	-PRON-	PRP
cord-008530-yni0poh9	323	4	might	may	MD
cord-008530-yni0poh9	323	5	be	be	VB
cord-008530-yni0poh9	323	6	speculated	speculate	VBN
cord-008530-yni0poh9	323	7	that	that	IN
cord-008530-yni0poh9	323	8	this	this	DT
cord-008530-yni0poh9	323	9	provides	provide	VBZ
cord-008530-yni0poh9	323	10	yet	yet	RB
cord-008530-yni0poh9	323	11	another	another	DT
cord-008530-yni0poh9	323	12	level	level	NN
cord-008530-yni0poh9	323	13	of	of	IN
cord-008530-yni0poh9	323	14	regulation	regulation	NN
cord-008530-yni0poh9	323	15	in	in	IN
cord-008530-yni0poh9	323	16	the	the	DT
cord-008530-yni0poh9	323	17	already	already	RB
cord-008530-yni0poh9	323	18	complex	complex	JJ
cord-008530-yni0poh9	323	19	cellular	cellular	JJ
cord-008530-yni0poh9	323	20	communication	communication	NN
cord-008530-yni0poh9	323	21	processes	process	NNS
cord-008530-yni0poh9	323	22	mediated	mediate	VBN
cord-008530-yni0poh9	323	23	by	by	IN
cord-008530-yni0poh9	323	24	the	the	DT
cord-008530-yni0poh9	323	25	chemokines	chemokine	NNS
cord-008530-yni0poh9	323	26	.	.	.
cord-008530-yni0poh9	324	1	CNS	CNS	NNP
cord-008530-yni0poh9	324	2	infection	infection	NN
cord-008530-yni0poh9	324	3	,	,	,
cord-008530-yni0poh9	324	4	with	with	IN
cord-008530-yni0poh9	324	5	a	a	DT
cord-008530-yni0poh9	324	6	number	number	NN
cord-008530-yni0poh9	324	7	of	of	IN
cord-008530-yni0poh9	324	8	different	different	JJ
cord-008530-yni0poh9	324	9	classes	class	NNS
cord-008530-yni0poh9	324	10	of	of	IN
cord-008530-yni0poh9	324	11	viruses	virus	NNS
cord-008530-yni0poh9	324	12	,	,	,
cord-008530-yni0poh9	324	13	can	can	MD
cord-008530-yni0poh9	324	14	provoke	provoke	VB
cord-008530-yni0poh9	324	15	vigorous	vigorous	JJ
cord-008530-yni0poh9	324	16	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	324	17	responses	response	NNS
cord-008530-yni0poh9	324	18	with	with	IN
cord-008530-yni0poh9	324	19	subsequent	subsequent	JJ
cord-008530-yni0poh9	324	20	recruitment	recruitment	NN
cord-008530-yni0poh9	324	21	of	of	IN
cord-008530-yni0poh9	324	22	large	large	JJ
cord-008530-yni0poh9	324	23	numbers	number	NNS
cord-008530-yni0poh9	324	24	of	of	IN
cord-008530-yni0poh9	324	25	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	324	26	(	(	-LRB-
cord-008530-yni0poh9	324	27	for	for	IN
cord-008530-yni0poh9	324	28	a	a	DT
cord-008530-yni0poh9	324	29	detailed	detailed	JJ
cord-008530-yni0poh9	324	30	discussion	discussion	NN
cord-008530-yni0poh9	324	31	of	of	IN
cord-008530-yni0poh9	324	32	this	this	DT
cord-008530-yni0poh9	324	33	topic	topic	NN
cord-008530-yni0poh9	324	34	,	,	,
cord-008530-yni0poh9	324	35	see	see	VB
cord-008530-yni0poh9	324	36	Chapter	chapter	NN
cord-008530-yni0poh9	324	37	6	6	CD
cord-008530-yni0poh9	324	38	in	in	IN
cord-008530-yni0poh9	324	39	this	this	DT
cord-008530-yni0poh9	324	40	volume	volume	NN
cord-008530-yni0poh9	324	41	)	)	-RRB-
cord-008530-yni0poh9	324	42	.	.	.
cord-008530-yni0poh9	325	1	In	in	IN
cord-008530-yni0poh9	325	2	view	view	NN
cord-008530-yni0poh9	325	3	of	of	IN
cord-008530-yni0poh9	325	4	their	-PRON-	PRP$
cord-008530-yni0poh9	325	5	functional	functional	JJ
cord-008530-yni0poh9	325	6	properties	property	NNS
cord-008530-yni0poh9	325	7	,	,	,
cord-008530-yni0poh9	325	8	increasing	increase	VBG
cord-008530-yni0poh9	325	9	interest	interest	NN
cord-008530-yni0poh9	325	10	has	have	VBZ
cord-008530-yni0poh9	325	11	focused	focus	VBN
cord-008530-yni0poh9	325	12	on	on	IN
cord-008530-yni0poh9	325	13	the	the	DT
cord-008530-yni0poh9	325	14	possible	possible	JJ
cord-008530-yni0poh9	325	15	involvement	involvement	NN
cord-008530-yni0poh9	325	16	of	of	IN
cord-008530-yni0poh9	325	17	chemokines	chemokine	NNS
cord-008530-yni0poh9	325	18	in	in	IN
cord-008530-yni0poh9	325	19	regulating	regulate	VBG
cord-008530-yni0poh9	325	20	CNS	cns	JJ
cord-008530-yni0poh9	325	21	leukocyte	leukocyte	NN
cord-008530-yni0poh9	325	22	migration	migration	NN
cord-008530-yni0poh9	325	23	during	during	IN
cord-008530-yni0poh9	325	24	viral	viral	JJ
cord-008530-yni0poh9	325	25	infection	infection	NN
cord-008530-yni0poh9	325	26	.	.	.
cord-008530-yni0poh9	326	1	However	however	RB
cord-008530-yni0poh9	326	2	,	,	,
cord-008530-yni0poh9	326	3	as	as	IN
cord-008530-yni0poh9	326	4	discussed	discuss	VBN
cord-008530-yni0poh9	326	5	below	below	RB
cord-008530-yni0poh9	326	6	,	,	,
cord-008530-yni0poh9	326	7	studies	study	NNS
cord-008530-yni0poh9	326	8	of	of	IN
cord-008530-yni0poh9	326	9	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	326	10	have	have	VBP
cord-008530-yni0poh9	326	11	revealed	reveal	VBN
cord-008530-yni0poh9	326	12	that	that	IN
cord-008530-yni0poh9	326	13	chemokine	chemokine	NN
cord-008530-yni0poh9	326	14	involvement	involvement	NN
cord-008530-yni0poh9	326	15	in	in	IN
cord-008530-yni0poh9	326	16	the	the	DT
cord-008530-yni0poh9	326	17	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	326	18	of	of	IN
cord-008530-yni0poh9	326	19	host	host	NN
cord-008530-yni0poh9	326	20	-	-	HYPH
cord-008530-yni0poh9	326	21	virus	virus	NN
cord-008530-yni0poh9	326	22	interactions	interaction	NNS
cord-008530-yni0poh9	326	23	extends	extend	VBZ
cord-008530-yni0poh9	326	24	well	well	RB
cord-008530-yni0poh9	326	25	beyond	beyond	IN
cord-008530-yni0poh9	326	26	leukocyte	leukocyte	NN
cord-008530-yni0poh9	326	27	migration	migration	NN
cord-008530-yni0poh9	326	28	.	.	.
cord-008530-yni0poh9	327	1	The	the	DT
cord-008530-yni0poh9	327	2	lentivirus	lentivirus	NN
cord-008530-yni0poh9	327	3	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	327	4	and	and	CC
cord-008530-yni0poh9	327	5	its	-PRON-	PRP$
cord-008530-yni0poh9	327	6	simian	simian	JJ
cord-008530-yni0poh9	327	7	counterpart	counterpart	NN
cord-008530-yni0poh9	327	8	,	,	,
cord-008530-yni0poh9	327	9	simian	simian	JJ
cord-008530-yni0poh9	327	10	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	327	11	virus	virus	NN
cord-008530-yni0poh9	327	12	(	(	-LRB-
cord-008530-yni0poh9	327	13	SIV	SIV	NNP
cord-008530-yni0poh9	327	14	)	)	-RRB-
cord-008530-yni0poh9	327	15	,	,	,
cord-008530-yni0poh9	327	16	both	both	DT
cord-008530-yni0poh9	327	17	infect	infect	VBP
cord-008530-yni0poh9	327	18	the	the	DT
cord-008530-yni0poh9	327	19	CNS	CNS	NNP
cord-008530-yni0poh9	327	20	and	and	CC
cord-008530-yni0poh9	327	21	are	be	VBP
cord-008530-yni0poh9	327	22	responsible	responsible	JJ
cord-008530-yni0poh9	327	23	for	for	IN
cord-008530-yni0poh9	327	24	causing	cause	VBG
cord-008530-yni0poh9	327	25	neurologic	neurologic	JJ
cord-008530-yni0poh9	327	26	disease	disease	NN
cord-008530-yni0poh9	327	27	.	.	.
cord-008530-yni0poh9	328	1	In	in	IN
cord-008530-yni0poh9	328	2	the	the	DT
cord-008530-yni0poh9	328	3	case	case	NN
cord-008530-yni0poh9	328	4	of	of	IN
cord-008530-yni0poh9	328	5	HIV	HIV	NNP
cord-008530-yni0poh9	328	6	,	,	,
cord-008530-yni0poh9	328	7	a	a	DT
cord-008530-yni0poh9	328	8	vast	vast	JJ
cord-008530-yni0poh9	328	9	amount	amount	NN
cord-008530-yni0poh9	328	10	of	of	IN
cord-008530-yni0poh9	328	11	research	research	NN
cord-008530-yni0poh9	328	12	effort	effort	NN
cord-008530-yni0poh9	328	13	focused	focus	VBN
cord-008530-yni0poh9	328	14	on	on	IN
cord-008530-yni0poh9	328	15	this	this	DT
cord-008530-yni0poh9	328	16	virus	virus	NN
cord-008530-yni0poh9	328	17	led	lead	VBD
cord-008530-yni0poh9	328	18	to	to	IN
cord-008530-yni0poh9	328	19	the	the	DT
cord-008530-yni0poh9	328	20	discovery	discovery	NN
cord-008530-yni0poh9	328	21	of	of	IN
cord-008530-yni0poh9	328	22	new	new	JJ
cord-008530-yni0poh9	328	23	chemokine	chemokine	NN
cord-008530-yni0poh9	328	24	receptors	receptor	NNS
cord-008530-yni0poh9	328	25	that	that	WDT
cord-008530-yni0poh9	328	26	proved	prove	VBD
cord-008530-yni0poh9	328	27	to	to	TO
cord-008530-yni0poh9	328	28	be	be	VB
cord-008530-yni0poh9	328	29	critical	critical	JJ
cord-008530-yni0poh9	328	30	for	for	IN
cord-008530-yni0poh9	328	31	understanding	understand	VBG
cord-008530-yni0poh9	328	32	the	the	DT
cord-008530-yni0poh9	328	33	process	process	NN
cord-008530-yni0poh9	328	34	of	of	IN
cord-008530-yni0poh9	328	35	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	328	36	entry	entry	NN
cord-008530-yni0poh9	328	37	into	into	IN
cord-008530-yni0poh9	328	38	cells	cell	NNS
cord-008530-yni0poh9	328	39	(	(	-LRB-
cord-008530-yni0poh9	328	40	Bleul	Bleul	NNP
cord-008530-yni0poh9	328	41	et	et	FW
cord-008530-yni0poh9	328	42	al	al	NNP
cord-008530-yni0poh9	328	43	.	.	NNP
cord-008530-yni0poh9	328	44	,	,	,
cord-008530-yni0poh9	328	45	1996	1996	CD
cord-008530-yni0poh9	328	46	;	;	:
cord-008530-yni0poh9	328	47	Feng	Feng	NNP
cord-008530-yni0poh9	328	48	et	et	FW
cord-008530-yni0poh9	328	49	al	al	NNP
cord-008530-yni0poh9	328	50	.	.	.
cord-008530-yni0poh9	329	1	,	,	,
cord-008530-yni0poh9	329	2	1996	1996	CD
cord-008530-yni0poh9	329	3	;	;	:
cord-008530-yni0poh9	329	4	Oberlin	Oberlin	NNP
cord-008530-yni0poh9	329	5	et	et	NNP
cord-008530-yni0poh9	329	6	al	al	NNP
cord-008530-yni0poh9	329	7	.	.	NNP
cord-008530-yni0poh9	329	8	,	,	,
cord-008530-yni0poh9	329	9	1996	1996	CD
cord-008530-yni0poh9	329	10	)	)	-RRB-
cord-008530-yni0poh9	329	11	.	.	.
cord-008530-yni0poh9	330	1	The	the	DT
cord-008530-yni0poh9	330	2	interactions	interaction	NNS
cord-008530-yni0poh9	330	3	between	between	IN
cord-008530-yni0poh9	330	4	this	this	DT
cord-008530-yni0poh9	330	5	virus	virus	NN
cord-008530-yni0poh9	330	6	and	and	CC
cord-008530-yni0poh9	330	7	the	the	DT
cord-008530-yni0poh9	330	8	host	host	NN
cord-008530-yni0poh9	330	9	CNS	CNS	NNP
cord-008530-yni0poh9	330	10	have	have	VBP
cord-008530-yni0poh9	330	11	also	also	RB
cord-008530-yni0poh9	330	12	been	be	VBN
cord-008530-yni0poh9	330	13	studied	study	VBN
cord-008530-yni0poh9	330	14	extensively	extensively	RB
cord-008530-yni0poh9	330	15	,	,	,
cord-008530-yni0poh9	330	16	and	and	CC
cord-008530-yni0poh9	330	17	more	more	RBR
cord-008530-yni0poh9	330	18	recently	recently	RB
cord-008530-yni0poh9	330	19	the	the	DT
cord-008530-yni0poh9	330	20	focus	focus	NN
cord-008530-yni0poh9	330	21	has	have	VBZ
cord-008530-yni0poh9	330	22	turned	turn	VBN
cord-008530-yni0poh9	330	23	to	to	IN
cord-008530-yni0poh9	330	24	the	the	DT
cord-008530-yni0poh9	330	25	chemokines	chemokine	NNS
cord-008530-yni0poh9	330	26	and	and	CC
cord-008530-yni0poh9	330	27	their	-PRON-	PRP$
cord-008530-yni0poh9	330	28	receptors	receptor	NNS
cord-008530-yni0poh9	330	29	.	.	.
cord-008530-yni0poh9	331	1	As	as	IN
cord-008530-yni0poh9	331	2	discussed	discuss	VBN
cord-008530-yni0poh9	331	3	below	below	RB
cord-008530-yni0poh9	331	4	,	,	,
cord-008530-yni0poh9	331	5	the	the	DT
cord-008530-yni0poh9	331	6	findings	finding	NNS
cord-008530-yni0poh9	331	7	point	point	NN
cord-008530-yni0poh9	331	8	to	to	IN
cord-008530-yni0poh9	331	9	a	a	DT
cord-008530-yni0poh9	331	10	significant	significant	JJ
cord-008530-yni0poh9	331	11	role	role	NN
cord-008530-yni0poh9	331	12	for	for	IN
cord-008530-yni0poh9	331	13	the	the	DT
cord-008530-yni0poh9	331	14	chemokines	chemokine	NNS
cord-008530-yni0poh9	331	15	and	and	CC
cord-008530-yni0poh9	331	16	the	the	DT
cord-008530-yni0poh9	331	17	chemokine	chemokine	NN
cord-008530-yni0poh9	331	18	receptors	receptor	NNS
cord-008530-yni0poh9	331	19	in	in	IN
cord-008530-yni0poh9	331	20	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	331	21	neuropathogenesis	neuropathogenesis	NNP
cord-008530-yni0poh9	331	22	.	.	.
cord-008530-yni0poh9	332	1	Although	although	IN
cord-008530-yni0poh9	332	2	CD4	CD4	NNP
cord-008530-yni0poh9	332	3	was	be	VBD
cord-008530-yni0poh9	332	4	identified	identify	VBN
cord-008530-yni0poh9	332	5	initially	initially	RB
cord-008530-yni0poh9	332	6	as	as	IN
cord-008530-yni0poh9	332	7	a	a	DT
cord-008530-yni0poh9	332	8	primary	primary	JJ
cord-008530-yni0poh9	332	9	receptor	receptor	NN
cord-008530-yni0poh9	332	10	for	for	IN
cord-008530-yni0poh9	332	11	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	332	12	binding	binding	NN
cord-008530-yni0poh9	332	13	and	and	CC
cord-008530-yni0poh9	332	14	entry	entry	NN
cord-008530-yni0poh9	332	15	,	,	,
cord-008530-yni0poh9	332	16	it	-PRON-	PRP
cord-008530-yni0poh9	332	17	was	be	VBD
cord-008530-yni0poh9	332	18	clear	clear	JJ
cord-008530-yni0poh9	332	19	this	this	DT
cord-008530-yni0poh9	332	20	could	could	MD
cord-008530-yni0poh9	332	21	not	not	RB
cord-008530-yni0poh9	332	22	account	account	VB
cord-008530-yni0poh9	332	23	for	for	IN
cord-008530-yni0poh9	332	24	many	many	JJ
cord-008530-yni0poh9	332	25	of	of	IN
cord-008530-yni0poh9	332	26	the	the	DT
cord-008530-yni0poh9	332	27	characteristics	characteristic	NNS
cord-008530-yni0poh9	332	28	of	of	IN
cord-008530-yni0poh9	332	29	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	332	30	infectivity	infectivity	NN
cord-008530-yni0poh9	332	31	,	,	,
cord-008530-yni0poh9	332	32	such	such	JJ
cord-008530-yni0poh9	332	33	as	as	IN
cord-008530-yni0poh9	332	34	the	the	DT
cord-008530-yni0poh9	332	35	existence	existence	NN
cord-008530-yni0poh9	332	36	of	of	IN
cord-008530-yni0poh9	332	37	different	different	JJ
cord-008530-yni0poh9	332	38	strains	strain	NNS
cord-008530-yni0poh9	332	39	of	of	IN
cord-008530-yni0poh9	332	40	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	332	41	with	with	IN
cord-008530-yni0poh9	332	42	selective	selective	JJ
cord-008530-yni0poh9	332	43	tropism	tropism	NN
cord-008530-yni0poh9	332	44	for	for	IN
cord-008530-yni0poh9	332	45	either	either	CC
cord-008530-yni0poh9	332	46	T	t	NN
cord-008530-yni0poh9	332	47	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	332	48	(	(	-LRB-
cord-008530-yni0poh9	332	49	Ttropic	Ttropic	NNP
cord-008530-yni0poh9	332	50	)	)	-RRB-
cord-008530-yni0poh9	332	51	or	or	CC
cord-008530-yni0poh9	332	52	monocytes	monocyte	NNS
cord-008530-yni0poh9	332	53	(	(	-LRB-
cord-008530-yni0poh9	332	54	M	M	NNP
cord-008530-yni0poh9	332	55	-	-	HYPH
cord-008530-yni0poh9	332	56	tropic	tropic	NNP
cord-008530-yni0poh9	332	57	)	)	-RRB-
cord-008530-yni0poh9	332	58	.	.	.
cord-008530-yni0poh9	333	1	A	a	DT
cord-008530-yni0poh9	333	2	clue	clue	NN
cord-008530-yni0poh9	333	3	to	to	IN
cord-008530-yni0poh9	333	4	the	the	DT
cord-008530-yni0poh9	333	5	identity	identity	NN
cord-008530-yni0poh9	333	6	of	of	IN
cord-008530-yni0poh9	333	7	other	other	JJ
cord-008530-yni0poh9	333	8	possible	possible	JJ
cord-008530-yni0poh9	333	9	cofactors	cofactor	NNS
cord-008530-yni0poh9	333	10	for	for	IN
cord-008530-yni0poh9	333	11	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	333	12	entry	entry	NN
cord-008530-yni0poh9	333	13	into	into	IN
cord-008530-yni0poh9	333	14	cells	cell	NNS
cord-008530-yni0poh9	333	15	came	come	VBD
cord-008530-yni0poh9	333	16	with	with	IN
cord-008530-yni0poh9	333	17	the	the	DT
cord-008530-yni0poh9	333	18	discovery	discovery	NN
cord-008530-yni0poh9	333	19	that	that	IN
cord-008530-yni0poh9	333	20	the	the	DT
cord-008530-yni0poh9	333	21	chemokines	chemokines	NNPS
cord-008530-yni0poh9	333	22	MIP	MIP	NNP
cord-008530-yni0poh9	333	23	-	-	HYPH
cord-008530-yni0poh9	333	24	la	la	NNP
cord-008530-yni0poh9	333	25	,	,	,
cord-008530-yni0poh9	333	26	MIP	MIP	NNP
cord-008530-yni0poh9	333	27	-	-	HYPH
cord-008530-yni0poh9	333	28	I~	I~	NNP
cord-008530-yni0poh9	333	29	,	,	,
cord-008530-yni0poh9	333	30	and	and	CC
cord-008530-yni0poh9	333	31	RANTES	RANTES	NNP
cord-008530-yni0poh9	333	32	produced	produce	VBN
cord-008530-yni0poh9	333	33	by	by	IN
cord-008530-yni0poh9	333	34	CD8	CD8	NNP
cord-008530-yni0poh9	333	35	÷	÷	NNP
cord-008530-yni0poh9	333	36	T	T	NNP
cord-008530-yni0poh9	333	37	cells	cell	NNS
cord-008530-yni0poh9	333	38	could	could	MD
cord-008530-yni0poh9	333	39	suppress	suppress	VB
cord-008530-yni0poh9	333	40	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	333	41	infection	infection	NN
cord-008530-yni0poh9	333	42	of	of	IN
cord-008530-yni0poh9	333	43	cultured	cultured	JJ
cord-008530-yni0poh9	333	44	cells	cell	NNS
cord-008530-yni0poh9	333	45	(	(	-LRB-
cord-008530-yni0poh9	333	46	Cocchi	Cocchi	NNP
cord-008530-yni0poh9	333	47	et	et	FW
cord-008530-yni0poh9	333	48	al	al	NNP
cord-008530-yni0poh9	333	49	.	.	NNP
cord-008530-yni0poh9	333	50	,	,	,
cord-008530-yni0poh9	333	51	1995	1995	CD
cord-008530-yni0poh9	333	52	)	)	-RRB-
cord-008530-yni0poh9	333	53	.	.	.
cord-008530-yni0poh9	334	1	A	a	DT
cord-008530-yni0poh9	334	2	seminal	seminal	JJ
cord-008530-yni0poh9	334	3	advance	advance	NN
cord-008530-yni0poh9	334	4	then	then	RB
cord-008530-yni0poh9	334	5	came	come	VBD
cord-008530-yni0poh9	334	6	when	when	WRB
cord-008530-yni0poh9	334	7	it	-PRON-	PRP
cord-008530-yni0poh9	334	8	was	be	VBD
cord-008530-yni0poh9	334	9	shown	show	VBN
cord-008530-yni0poh9	334	10	that	that	IN
cord-008530-yni0poh9	334	11	in	in	IN
cord-008530-yni0poh9	334	12	addition	addition	NN
cord-008530-yni0poh9	334	13	to	to	IN
cord-008530-yni0poh9	334	14	CD4	CD4	NNP
cord-008530-yni0poh9	334	15	,	,	,
cord-008530-yni0poh9	334	16	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	334	17	was	be	VBD
cord-008530-yni0poh9	334	18	required	require	VBN
cord-008530-yni0poh9	334	19	for	for	IN
cord-008530-yni0poh9	334	20	T	T	NNP
cord-008530-yni0poh9	334	21	-	-	HYPH
cord-008530-yni0poh9	334	22	tropic	tropic	NNP
cord-008530-yni0poh9	334	23	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	334	24	strains	strain	NNS
cord-008530-yni0poh9	334	25	to	to	TO
cord-008530-yni0poh9	334	26	infect	infect	VB
cord-008530-yni0poh9	334	27	host	host	NN
cord-008530-yni0poh9	334	28	cells	cell	NNS
cord-008530-yni0poh9	334	29	(	(	-LRB-
cord-008530-yni0poh9	334	30	Bleul	Bleul	NNP
cord-008530-yni0poh9	334	31	et	et	FW
cord-008530-yni0poh9	334	32	al	al	NNP
cord-008530-yni0poh9	334	33	.	.	NNP
cord-008530-yni0poh9	334	34	,	,	,
cord-008530-yni0poh9	334	35	1996	1996	CD
cord-008530-yni0poh9	334	36	;	;	.
cord-008530-yni0poh9	335	1	Feng	Feng	NNP
cord-008530-yni0poh9	335	2	et	et	FW
cord-008530-yni0poh9	335	3	al	al	NNP
cord-008530-yni0poh9	335	4	.	.	.
cord-008530-yni0poh9	336	1	,	,	,
cord-008530-yni0poh9	336	2	1996	1996	CD
cord-008530-yni0poh9	336	3	;	;	:
cord-008530-yni0poh9	336	4	Oberlin	Oberlin	NNP
cord-008530-yni0poh9	336	5	et	et	NNP
cord-008530-yni0poh9	336	6	al	al	NNP
cord-008530-yni0poh9	336	7	.	.	NNP
cord-008530-yni0poh9	336	8	,	,	,
cord-008530-yni0poh9	336	9	1996	1996	CD
cord-008530-yni0poh9	336	10	)	)	-RRB-
cord-008530-yni0poh9	336	11	.	.	.
cord-008530-yni0poh9	337	1	The	the	DT
cord-008530-yni0poh9	337	2	identification	identification	NN
cord-008530-yni0poh9	337	3	of	of	IN
cord-008530-yni0poh9	337	4	CCR5	CCR5	NNP
cord-008530-yni0poh9	337	5	as	as	IN
cord-008530-yni0poh9	337	6	a	a	DT
cord-008530-yni0poh9	337	7	receptor	receptor	NN
cord-008530-yni0poh9	337	8	for	for	IN
cord-008530-yni0poh9	337	9	MIP	MIP	NNP
cord-008530-yni0poh9	337	10	-	-	HYPH
cord-008530-yni0poh9	337	11	la	la	NNP
cord-008530-yni0poh9	337	12	,	,	,
cord-008530-yni0poh9	337	13	MIP	MIP	NNP
cord-008530-yni0poh9	337	14	-	-	HYPH
cord-008530-yni0poh9	337	15	I~	I~	NNP
cord-008530-yni0poh9	337	16	,	,	,
cord-008530-yni0poh9	337	17	and	and	CC
cord-008530-yni0poh9	337	18	RANTES	RANTES	NNP
cord-008530-yni0poh9	337	19	soon	soon	RB
cord-008530-yni0poh9	337	20	led	lead	VBD
cord-008530-yni0poh9	337	21	to	to	IN
cord-008530-yni0poh9	337	22	the	the	DT
cord-008530-yni0poh9	337	23	demonstration	demonstration	NN
cord-008530-yni0poh9	337	24	that	that	WDT
cord-008530-yni0poh9	337	25	CCR5	CCR5	NNP
cord-008530-yni0poh9	337	26	served	serve	VBD
cord-008530-yni0poh9	337	27	as	as	IN
cord-008530-yni0poh9	337	28	a	a	DT
cord-008530-yni0poh9	337	29	prominent	prominent	JJ
cord-008530-yni0poh9	337	30	coreceptor	coreceptor	NN
cord-008530-yni0poh9	337	31	for	for	IN
cord-008530-yni0poh9	337	32	cell	cell	NN
cord-008530-yni0poh9	337	33	entry	entry	NN
cord-008530-yni0poh9	337	34	by	by	IN
cord-008530-yni0poh9	337	35	M	M	NNP
cord-008530-yni0poh9	337	36	-	-	HYPH
cord-008530-yni0poh9	337	37	tropic	tropic	NNP
cord-008530-yni0poh9	337	38	strains	strain	NNS
cord-008530-yni0poh9	338	1	ofHIV-1	ofhiv-1	XX
cord-008530-yni0poh9	339	1	(	(	-LRB-
cord-008530-yni0poh9	339	2	Alkhatib	Alkhatib	NNP
cord-008530-yni0poh9	339	3	et	et	NNP
cord-008530-yni0poh9	339	4	al	al	NNP
cord-008530-yni0poh9	339	5	.	.	.
cord-008530-yni0poh9	340	1	,	,	,
cord-008530-yni0poh9	340	2	1996	1996	CD
cord-008530-yni0poh9	340	3	;	;	:
cord-008530-yni0poh9	340	4	Choe	Choe	NNP
cord-008530-yni0poh9	340	5	et	et	NNP
cord-008530-yni0poh9	340	6	al	al	NNP
cord-008530-yni0poh9	340	7	.	.	.
cord-008530-yni0poh9	341	1	,	,	,
cord-008530-yni0poh9	341	2	1996	1996	CD
cord-008530-yni0poh9	341	3	;	;	:
cord-008530-yni0poh9	341	4	Deng	Deng	NNP
cord-008530-yni0poh9	341	5	et	et	FW
cord-008530-yni0poh9	341	6	al	al	NNP
cord-008530-yni0poh9	341	7	.	.	.
cord-008530-yni0poh9	342	1	,	,	,
cord-008530-yni0poh9	342	2	1996	1996	CD
cord-008530-yni0poh9	342	3	;	;	:
cord-008530-yni0poh9	342	4	Doranz	Doranz	NNP
cord-008530-yni0poh9	342	5	et	et	NNP
cord-008530-yni0poh9	342	6	al	al	NNP
cord-008530-yni0poh9	342	7	.	.	.
cord-008530-yni0poh9	343	1	,	,	,
cord-008530-yni0poh9	343	2	1996	1996	CD
cord-008530-yni0poh9	343	3	;	;	:
cord-008530-yni0poh9	343	4	Dragic	Dragic	NNP
cord-008530-yni0poh9	343	5	et	et	NNP
cord-008530-yni0poh9	343	6	al	al	NNP
cord-008530-yni0poh9	343	7	.	.	NNP
cord-008530-yni0poh9	343	8	,	,	,
cord-008530-yni0poh9	343	9	1996	1996	CD
cord-008530-yni0poh9	343	10	)	)	-RRB-
cord-008530-yni0poh9	343	11	.	.	.
cord-008530-yni0poh9	344	1	The	the	DT
cord-008530-yni0poh9	344	2	factors	factor	NNS
cord-008530-yni0poh9	344	3	that	that	WDT
cord-008530-yni0poh9	344	4	govern	govern	VBP
cord-008530-yni0poh9	344	5	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	344	6	entry	entry	NN
cord-008530-yni0poh9	344	7	into	into	IN
cord-008530-yni0poh9	344	8	cells	cell	NNS
cord-008530-yni0poh9	344	9	are	be	VBP
cord-008530-yni0poh9	344	10	clearly	clearly	RB
cord-008530-yni0poh9	344	11	very	very	RB
cord-008530-yni0poh9	344	12	complex	complex	JJ
cord-008530-yni0poh9	344	13	,	,	,
cord-008530-yni0poh9	344	14	and	and	CC
cord-008530-yni0poh9	344	15	while	while	IN
cord-008530-yni0poh9	344	16	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	344	17	and	and	CC
cord-008530-yni0poh9	344	18	CCR5	CCR5	NNP
cord-008530-yni0poh9	344	19	are	be	VBP
cord-008530-yni0poh9	344	20	the	the	DT
cord-008530-yni0poh9	344	21	major	major	JJ
cord-008530-yni0poh9	344	22	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	344	23	for	for	IN
cord-008530-yni0poh9	344	24	Ttropic	Ttropic	NNP
cord-008530-yni0poh9	344	25	and	and	CC
cord-008530-yni0poh9	344	26	M	M	NNP
cord-008530-yni0poh9	344	27	-	-	HYPH
cord-008530-yni0poh9	344	28	tropic	tropic	NNP
cord-008530-yni0poh9	344	29	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	344	30	strains	strain	NNS
cord-008530-yni0poh9	344	31	,	,	,
cord-008530-yni0poh9	344	32	a	a	DT
cord-008530-yni0poh9	344	33	large	large	JJ
cord-008530-yni0poh9	344	34	number	number	NN
cord-008530-yni0poh9	344	35	of	of	IN
cord-008530-yni0poh9	344	36	other	other	JJ
cord-008530-yni0poh9	344	37	chemokine	chemokine	NN
cord-008530-yni0poh9	344	38	receptors	receptor	NNS
cord-008530-yni0poh9	344	39	including	include	VBG
cord-008530-yni0poh9	344	40	CCR2b	CCR2b	NNP
cord-008530-yni0poh9	344	41	,	,	,
cord-008530-yni0poh9	344	42	CCR3	CCR3	NNP
cord-008530-yni0poh9	344	43	,	,	,
cord-008530-yni0poh9	344	44	and	and	CC
cord-008530-yni0poh9	344	45	CCR8	CCR8	NNP
cord-008530-yni0poh9	344	46	,	,	,
cord-008530-yni0poh9	344	47	the	the	DT
cord-008530-yni0poh9	344	48	US28	US28	NNP
cord-008530-yni0poh9	344	49	chemokine	chemokine	NN
cord-008530-yni0poh9	344	50	receptor	receptor	NN
cord-008530-yni0poh9	344	51	homolog	homolog	NN
cord-008530-yni0poh9	344	52	encoded	encode	VBN
cord-008530-yni0poh9	344	53	by	by	IN
cord-008530-yni0poh9	344	54	cytomegalovirus	cytomegalovirus	NNP
cord-008530-yni0poh9	344	55	,	,	,
cord-008530-yni0poh9	344	56	as	as	RB
cord-008530-yni0poh9	344	57	well	well	RB
cord-008530-yni0poh9	344	58	as	as	IN
cord-008530-yni0poh9	344	59	the	the	DT
cord-008530-yni0poh9	344	60	orphan	orphan	NN
cord-008530-yni0poh9	344	61	chemokine	chemokine	NN
cord-008530-yni0poh9	344	62	receptors	receptor	NNS
cord-008530-yni0poh9	344	63	gprl	gprl	NNP
cord-008530-yni0poh9	344	64	,	,	,
cord-008530-yni0poh9	344	65	gpr15	gpr15	''
cord-008530-yni0poh9	344	66	/	/	SYM
cord-008530-yni0poh9	344	67	BOB	BOB	NNP
cord-008530-yni0poh9	344	68	,	,	,
cord-008530-yni0poh9	344	69	and	and	CC
cord-008530-yni0poh9	344	70	STRL33	STRL33	NNP
cord-008530-yni0poh9	344	71	/	/	SYM
cord-008530-yni0poh9	344	72	BONZO	BONZO	NNP
cord-008530-yni0poh9	344	73	,	,	,
cord-008530-yni0poh9	344	74	can	can	MD
cord-008530-yni0poh9	344	75	function	function	VB
cord-008530-yni0poh9	344	76	as	as	IN
cord-008530-yni0poh9	344	77	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	344	78	for	for	IN
cord-008530-yni0poh9	344	79	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	344	80	infection	infection	NN
cord-008530-yni0poh9	345	1	(	(	-LRB-
cord-008530-yni0poh9	345	2	Deng	Deng	NNP
cord-008530-yni0poh9	345	3	et	et	NNP
cord-008530-yni0poh9	345	4	al	al	NNP
cord-008530-yni0poh9	345	5	.	.	NNP
cord-008530-yni0poh9	345	6	,	,	,
cord-008530-yni0poh9	345	7	1997	1997	CD
cord-008530-yni0poh9	345	8	;	;	:
cord-008530-yni0poh9	345	9	Heiber	Heiber	NNP
cord-008530-yni0poh9	345	10	et	et	NNP
cord-008530-yni0poh9	345	11	al	al	NNP
cord-008530-yni0poh9	345	12	.	.	NNP
cord-008530-yni0poh9	345	13	,	,	,
cord-008530-yni0poh9	345	14	1996	1996	CD
cord-008530-yni0poh9	345	15	;	;	.
cord-008530-yni0poh9	346	1	Liao	Liao	NNP
cord-008530-yni0poh9	346	2	et	et	NNP
cord-008530-yni0poh9	346	3	al	al	NNP
cord-008530-yni0poh9	346	4	.	.	NNP
cord-008530-yni0poh9	346	5	,	,	,
cord-008530-yni0poh9	346	6	1997	1997	CD
cord-008530-yni0poh9	346	7	;	;	:
cord-008530-yni0poh9	346	8	Littman	Littman	NNP
cord-008530-yni0poh9	346	9	,	,	,
cord-008530-yni0poh9	346	10	1998	1998	CD
cord-008530-yni0poh9	346	11	;	;	:
cord-008530-yni0poh9	346	12	Marchese	Marchese	NNP
cord-008530-yni0poh9	346	13	et	et	NNP
cord-008530-yni0poh9	346	14	al	al	NNP
cord-008530-yni0poh9	346	15	.	.	NNP
cord-008530-yni0poh9	346	16	,	,	,
cord-008530-yni0poh9	346	17	1994	1994	CD
cord-008530-yni0poh9	346	18	;	;	:
cord-008530-yni0poh9	346	19	Pleskoffet	Pleskoffet	NNP
cord-008530-yni0poh9	346	20	al	al	NNP
cord-008530-yni0poh9	346	21	.	.	NNP
cord-008530-yni0poh9	346	22	,	,	,
cord-008530-yni0poh9	346	23	1997	1997	CD
cord-008530-yni0poh9	346	24	)	)	-RRB-
cord-008530-yni0poh9	346	25	.	.	.
cord-008530-yni0poh9	347	1	The	the	DT
cord-008530-yni0poh9	347	2	importance	importance	NN
cord-008530-yni0poh9	347	3	of	of	IN
cord-008530-yni0poh9	347	4	the	the	DT
cord-008530-yni0poh9	347	5	chemokine	chemokine	NN
cord-008530-yni0poh9	347	6	receptors	receptor	NNS
cord-008530-yni0poh9	347	7	for	for	IN
cord-008530-yni0poh9	347	8	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	347	9	infection	infection	NN
cord-008530-yni0poh9	347	10	in	in	IN
cord-008530-yni0poh9	347	11	vivo	vivo	NNP
cord-008530-yni0poh9	347	12	is	be	VBZ
cord-008530-yni0poh9	347	13	illustrated	illustrate	VBN
cord-008530-yni0poh9	347	14	in	in	IN
cord-008530-yni0poh9	347	15	the	the	DT
cord-008530-yni0poh9	347	16	case	case	NN
cord-008530-yni0poh9	347	17	of	of	IN
cord-008530-yni0poh9	347	18	individuals	individual	NNS
cord-008530-yni0poh9	347	19	that	that	WDT
cord-008530-yni0poh9	347	20	are	be	VBP
cord-008530-yni0poh9	347	21	homozygous	homozygous	JJ
cord-008530-yni0poh9	347	22	for	for	IN
cord-008530-yni0poh9	347	23	a	a	DT
cord-008530-yni0poh9	347	24	32	32	CD
cord-008530-yni0poh9	347	25	base	base	NN
cord-008530-yni0poh9	347	26	pair	pair	NN
cord-008530-yni0poh9	347	27	mutation	mutation	NN
cord-008530-yni0poh9	347	28	in	in	IN
cord-008530-yni0poh9	347	29	the	the	DT
cord-008530-yni0poh9	347	30	CCR5	CCR5	NNP
cord-008530-yni0poh9	347	31	gene	gene	NN
cord-008530-yni0poh9	347	32	and	and	CC
cord-008530-yni0poh9	347	33	who	who	WP
cord-008530-yni0poh9	347	34	have	have	VBP
cord-008530-yni0poh9	347	35	marked	mark	VBN
cord-008530-yni0poh9	347	36	resistance	resistance	NN
cord-008530-yni0poh9	347	37	toward	toward	IN
cord-008530-yni0poh9	347	38	HIV	HIV	NNP
cord-008530-yni0poh9	347	39	infection	infection	NN
cord-008530-yni0poh9	348	1	(	(	-LRB-
cord-008530-yni0poh9	348	2	Biti	Biti	NNP
cord-008530-yni0poh9	348	3	et	et	FW
cord-008530-yni0poh9	348	4	al	al	NNP
cord-008530-yni0poh9	348	5	.	.	NNP
cord-008530-yni0poh9	348	6	,	,	,
cord-008530-yni0poh9	348	7	1997	1997	CD
cord-008530-yni0poh9	348	8	;	;	.
cord-008530-yni0poh9	349	1	O'Brien	O'Brien	NNP
cord-008530-yni0poh9	349	2	et	et	NNP
cord-008530-yni0poh9	349	3	al	al	NNP
cord-008530-yni0poh9	349	4	.	.	NNP
cord-008530-yni0poh9	349	5	,	,	,
cord-008530-yni0poh9	349	6	1997	1997	CD
cord-008530-yni0poh9	350	1	;	;	:
cord-008530-yni0poh9	350	2	Theodorou	Theodorou	NNP
cord-008530-yni0poh9	350	3	et	et	NNP
cord-008530-yni0poh9	350	4	al	al	NNP
cord-008530-yni0poh9	350	5	.	.	NNP
cord-008530-yni0poh9	350	6	,	,	,
cord-008530-yni0poh9	350	7	1997	1997	CD
cord-008530-yni0poh9	350	8	)	)	-RRB-
cord-008530-yni0poh9	350	9	.	.	.
cord-008530-yni0poh9	351	1	In	in	IN
cord-008530-yni0poh9	351	2	addition	addition	NN
cord-008530-yni0poh9	351	3	,	,	,
cord-008530-yni0poh9	351	4	it	-PRON-	PRP
cord-008530-yni0poh9	351	5	has	have	VBZ
cord-008530-yni0poh9	351	6	been	be	VBN
cord-008530-yni0poh9	351	7	reported	report	VBN
cord-008530-yni0poh9	351	8	that	that	IN
cord-008530-yni0poh9	351	9	individuals	individual	NNS
cord-008530-yni0poh9	351	10	with	with	IN
cord-008530-yni0poh9	351	11	mutations	mutation	NNS
cord-008530-yni0poh9	351	12	in	in	IN
cord-008530-yni0poh9	351	13	the	the	DT
cord-008530-yni0poh9	351	14	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	351	15	and	and	CC
cord-008530-yni0poh9	351	16	CCR2	CCR2	NNP
cord-008530-yni0poh9	351	17	genes	gene	NNS
cord-008530-yni0poh9	351	18	also	also	RB
cord-008530-yni0poh9	351	19	exhibit	exhibit	VBP
cord-008530-yni0poh9	351	20	a	a	DT
cord-008530-yni0poh9	351	21	retarded	retarded	JJ
cord-008530-yni0poh9	351	22	progression	progression	NN
cord-008530-yni0poh9	351	23	of	of	IN
cord-008530-yni0poh9	351	24	HIV	HIV	NNP
cord-008530-yni0poh9	351	25	-	-	HYPH
cord-008530-yni0poh9	351	26	l	l	NN
cord-008530-yni0poh9	351	27	-	-	HYPH
cord-008530-yni0poh9	351	28	associated	associate	VBN
cord-008530-yni0poh9	351	29	disease	disease	NN
cord-008530-yni0poh9	351	30	.	.	.
cord-008530-yni0poh9	352	1	A	a	DT
cord-008530-yni0poh9	352	2	significant	significant	JJ
cord-008530-yni0poh9	352	3	number	number	NN
cord-008530-yni0poh9	352	4	of	of	IN
cord-008530-yni0poh9	352	5	patients	patient	NNS
cord-008530-yni0poh9	352	6	with	with	IN
cord-008530-yni0poh9	352	7	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	352	8	infection	infection	NN
cord-008530-yni0poh9	352	9	suffer	suffer	VBP
cord-008530-yni0poh9	352	10	from	from	IN
cord-008530-yni0poh9	352	11	a	a	DT
cord-008530-yni0poh9	352	12	variety	variety	NN
cord-008530-yni0poh9	352	13	of	of	IN
cord-008530-yni0poh9	352	14	neurological	neurological	JJ
cord-008530-yni0poh9	352	15	problems	problem	NNS
cord-008530-yni0poh9	352	16	known	know	VBN
cord-008530-yni0poh9	352	17	collectively	collectively	RB
cord-008530-yni0poh9	352	18	as	as	IN
cord-008530-yni0poh9	352	19	HIV	HIV	NNP
cord-008530-yni0poh9	352	20	-	-	HYPH
cord-008530-yni0poh9	352	21	l	l	NNP
cord-008530-yni0poh9	352	22	-	-	HYPH
cord-008530-yni0poh9	352	23	associated	associate	VBN
cord-008530-yni0poh9	352	24	cognitive	cognitive	JJ
cord-008530-yni0poh9	352	25	and	and	CC
cord-008530-yni0poh9	352	26	motor	motor	NN
cord-008530-yni0poh9	352	27	disorder	disorder	NN
cord-008530-yni0poh9	352	28	,	,	,
cord-008530-yni0poh9	352	29	or	or	CC
cord-008530-yni0poh9	352	30	"	"	``
cord-008530-yni0poh9	352	31	neuroAIDS	neuroaids	FW
cord-008530-yni0poh9	352	32	"	"	''
cord-008530-yni0poh9	352	33	(	(	-LRB-
cord-008530-yni0poh9	352	34	see	see	VB
cord-008530-yni0poh9	352	35	Chapter	chapter	NN
cord-008530-yni0poh9	352	36	18	18	CD
cord-008530-yni0poh9	352	37	in	in	IN
cord-008530-yni0poh9	352	38	this	this	DT
cord-008530-yni0poh9	352	39	volume	volume	NN
cord-008530-yni0poh9	352	40	)	)	-RRB-
cord-008530-yni0poh9	352	41	.	.	.
cord-008530-yni0poh9	353	1	In	in	IN
cord-008530-yni0poh9	353	2	its	-PRON-	PRP$
cord-008530-yni0poh9	353	3	severest	severe	JJS
cord-008530-yni0poh9	353	4	form	form	NN
cord-008530-yni0poh9	353	5	,	,	,
cord-008530-yni0poh9	353	6	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	353	7	can	can	MD
cord-008530-yni0poh9	353	8	be	be	VB
cord-008530-yni0poh9	353	9	responsible	responsible	JJ
cord-008530-yni0poh9	353	10	for	for	IN
cord-008530-yni0poh9	353	11	subcortical	subcortical	JJ
cord-008530-yni0poh9	353	12	dementia	dementia	NN
cord-008530-yni0poh9	353	13	,	,	,
cord-008530-yni0poh9	353	14	memory	memory	NN
cord-008530-yni0poh9	353	15	impairment	impairment	NN
cord-008530-yni0poh9	353	16	,	,	,
cord-008530-yni0poh9	353	17	and	and	CC
cord-008530-yni0poh9	353	18	motor	motor	NN
cord-008530-yni0poh9	353	19	disorder	disorder	NN
cord-008530-yni0poh9	353	20	.	.	.
cord-008530-yni0poh9	354	1	Although	although	IN
cord-008530-yni0poh9	354	2	the	the	DT
cord-008530-yni0poh9	354	3	neuropathology	neuropathology	NN
cord-008530-yni0poh9	354	4	of	of	IN
cord-008530-yni0poh9	354	5	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	354	6	is	be	VBZ
cord-008530-yni0poh9	354	7	often	often	RB
cord-008530-yni0poh9	354	8	variable	variable	JJ
cord-008530-yni0poh9	354	9	,	,	,
cord-008530-yni0poh9	354	10	typical	typical	JJ
cord-008530-yni0poh9	354	11	features	feature	NNS
cord-008530-yni0poh9	354	12	include	include	VBP
cord-008530-yni0poh9	354	13	formation	formation	NN
cord-008530-yni0poh9	354	14	of	of	IN
cord-008530-yni0poh9	354	15	multinucleated	multinucleated	JJ
cord-008530-yni0poh9	354	16	giant	giant	JJ
cord-008530-yni0poh9	354	17	cells	cell	NNS
cord-008530-yni0poh9	354	18	,	,	,
cord-008530-yni0poh9	354	19	diffuse	diffuse	VB
cord-008530-yni0poh9	354	20	gliosis	gliosis	NN
cord-008530-yni0poh9	354	21	,	,	,
cord-008530-yni0poh9	354	22	myelin	myelin	NN
cord-008530-yni0poh9	354	23	pallor	pallor	NN
cord-008530-yni0poh9	354	24	,	,	,
cord-008530-yni0poh9	354	25	and	and	CC
cord-008530-yni0poh9	354	26	increased	increase	VBN
cord-008530-yni0poh9	354	27	blood	blood	NN
cord-008530-yni0poh9	354	28	-	-	HYPH
cord-008530-yni0poh9	354	29	brain	brain	NN
cord-008530-yni0poh9	354	30	barrier	barrier	NN
cord-008530-yni0poh9	354	31	permeability	permeability	NN
cord-008530-yni0poh9	354	32	.	.	.
cord-008530-yni0poh9	355	1	Neurodegeneration	Neurodegeneration	NNP
cord-008530-yni0poh9	355	2	,	,	,
cord-008530-yni0poh9	355	3	with	with	IN
cord-008530-yni0poh9	355	4	disrupted	disrupt	VBN
cord-008530-yni0poh9	355	5	synaptodendritic	synaptodendritic	JJ
cord-008530-yni0poh9	355	6	organization	organization	NN
cord-008530-yni0poh9	355	7	and	and	CC
cord-008530-yni0poh9	355	8	loss	loss	NN
cord-008530-yni0poh9	355	9	of	of	IN
cord-008530-yni0poh9	355	10	neurons	neuron	NNS
cord-008530-yni0poh9	355	11	,	,	,
cord-008530-yni0poh9	355	12	is	be	VBZ
cord-008530-yni0poh9	355	13	observed	observe	VBN
cord-008530-yni0poh9	355	14	in	in	IN
cord-008530-yni0poh9	355	15	many	many	JJ
cord-008530-yni0poh9	355	16	but	but	CC
cord-008530-yni0poh9	355	17	not	not	RB
cord-008530-yni0poh9	355	18	all	all	DT
cord-008530-yni0poh9	355	19	cases	case	NNS
cord-008530-yni0poh9	355	20	(	(	-LRB-
cord-008530-yni0poh9	355	21	Everall	Everall	NNP
cord-008530-yni0poh9	355	22	et	et	FW
cord-008530-yni0poh9	355	23	al	al	NNP
cord-008530-yni0poh9	355	24	.	.	NNP
cord-008530-yni0poh9	355	25	,	,	,
cord-008530-yni0poh9	355	26	1993	1993	CD
cord-008530-yni0poh9	355	27	)	)	-RRB-
cord-008530-yni0poh9	355	28	.	.	.
cord-008530-yni0poh9	356	1	The	the	DT
cord-008530-yni0poh9	356	2	cause	cause	NN
cord-008530-yni0poh9	356	3	of	of	IN
cord-008530-yni0poh9	356	4	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	356	5	and	and	CC
cord-008530-yni0poh9	356	6	the	the	DT
cord-008530-yni0poh9	356	7	mechanisms	mechanism	NNS
cord-008530-yni0poh9	356	8	that	that	WDT
cord-008530-yni0poh9	356	9	lead	lead	VBP
cord-008530-yni0poh9	356	10	to	to	IN
cord-008530-yni0poh9	356	11	brain	brain	NN
cord-008530-yni0poh9	356	12	injury	injury	NN
cord-008530-yni0poh9	356	13	are	be	VBP
cord-008530-yni0poh9	356	14	not	not	RB
cord-008530-yni0poh9	356	15	well	well	RB
cord-008530-yni0poh9	356	16	understood	understand	VBN
cord-008530-yni0poh9	356	17	,	,	,
cord-008530-yni0poh9	356	18	although	although	IN
cord-008530-yni0poh9	356	19	a	a	DT
cord-008530-yni0poh9	356	20	combination	combination	NN
cord-008530-yni0poh9	356	21	of	of	IN
cord-008530-yni0poh9	356	22	both	both	DT
cord-008530-yni0poh9	356	23	host	host	NN
cord-008530-yni0poh9	356	24	-	-	:
cord-008530-yni0poh9	356	25	and	and	CC
cord-008530-yni0poh9	356	26	HIV	HIV	NNP
cord-008530-yni0poh9	356	27	-	-	HYPH
cord-008530-yni0poh9	356	28	derived	derive	VBN
cord-008530-yni0poh9	356	29	toxic	toxic	JJ
cord-008530-yni0poh9	356	30	factors	factor	NNS
cord-008530-yni0poh9	356	31	is	be	VBZ
cord-008530-yni0poh9	356	32	likely	likely	JJ
cord-008530-yni0poh9	356	33	to	to	TO
cord-008530-yni0poh9	356	34	be	be	VB
cord-008530-yni0poh9	356	35	involved	involve	VBN
cord-008530-yni0poh9	356	36	(	(	-LRB-
cord-008530-yni0poh9	356	37	Gendelman	Gendelman	NNP
cord-008530-yni0poh9	356	38	et	et	FW
cord-008530-yni0poh9	356	39	al	al	NNP
cord-008530-yni0poh9	356	40	.	.	NNP
cord-008530-yni0poh9	356	41	,	,	,
cord-008530-yni0poh9	356	42	1997	1997	CD
cord-008530-yni0poh9	356	43	)	)	-RRB-
cord-008530-yni0poh9	356	44	.	.	.
cord-008530-yni0poh9	357	1	It	-PRON-	PRP
cord-008530-yni0poh9	357	2	is	be	VBZ
cord-008530-yni0poh9	357	3	clear	clear	JJ
cord-008530-yni0poh9	357	4	,	,	,
cord-008530-yni0poh9	357	5	however	however	RB
cord-008530-yni0poh9	357	6	,	,	,
cord-008530-yni0poh9	357	7	that	that	IN
cord-008530-yni0poh9	357	8	productive	productive	JJ
cord-008530-yni0poh9	357	9	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	357	10	infection	infection	NN
cord-008530-yni0poh9	357	11	of	of	IN
cord-008530-yni0poh9	357	12	the	the	DT
cord-008530-yni0poh9	357	13	CNS	CNS	NNP
cord-008530-yni0poh9	357	14	is	be	VBZ
cord-008530-yni0poh9	357	15	largely	largely	RB
cord-008530-yni0poh9	357	16	restricted	restrict	VBN
cord-008530-yni0poh9	357	17	to	to	IN
cord-008530-yni0poh9	357	18	macrophage	macrophage	NN
cord-008530-yni0poh9	357	19	/	/	SYM
cord-008530-yni0poh9	357	20	microglia	microglia	NNS
cord-008530-yni0poh9	357	21	and	and	CC
cord-008530-yni0poh9	357	22	infrequently	infrequently	RB
cord-008530-yni0poh9	357	23	to	to	IN
cord-008530-yni0poh9	357	24	neurons	neuron	NNS
cord-008530-yni0poh9	357	25	or	or	CC
cord-008530-yni0poh9	357	26	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	357	27	.	.	.
cord-008530-yni0poh9	358	1	Infection	infection	NN
cord-008530-yni0poh9	358	2	of	of	IN
cord-008530-yni0poh9	358	3	the	the	DT
cord-008530-yni0poh9	358	4	CNS	CNS	NNP
cord-008530-yni0poh9	358	5	is	be	VBZ
cord-008530-yni0poh9	358	6	thought	think	VBN
cord-008530-yni0poh9	358	7	to	to	TO
cord-008530-yni0poh9	358	8	result	result	VB
cord-008530-yni0poh9	358	9	from	from	IN
cord-008530-yni0poh9	358	10	the	the	DT
cord-008530-yni0poh9	358	11	entry	entry	NN
cord-008530-yni0poh9	358	12	of	of	IN
cord-008530-yni0poh9	358	13	HIV	HIV	NNP
cord-008530-yni0poh9	358	14	-	-	HYPH
cord-008530-yni0poh9	358	15	l	l	NNP
cord-008530-yni0poh9	358	16	-	-	HYPH
cord-008530-yni0poh9	358	17	infected	infect	VBN
cord-008530-yni0poh9	358	18	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	358	19	or	or	CC
cord-008530-yni0poh9	358	20	macrophages--	macrophages--	CD
cord-008530-yni0poh9	359	1	the	the	DT
cord-008530-yni0poh9	359	2	subsequent	subsequent	JJ
cord-008530-yni0poh9	359	3	presence	presence	NN
cord-008530-yni0poh9	359	4	of	of	IN
cord-008530-yni0poh9	359	5	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	359	6	proteins	protein	NNS
cord-008530-yni0poh9	359	7	in	in	IN
cord-008530-yni0poh9	359	8	microglia	microglia	NN
cord-008530-yni0poh9	359	9	and	and	CC
cord-008530-yni0poh9	359	10	multinucleated	multinucleated	JJ
cord-008530-yni0poh9	359	11	giant	giant	JJ
cord-008530-yni0poh9	359	12	cells	cell	NNS
cord-008530-yni0poh9	359	13	suggests	suggest	VBZ
cord-008530-yni0poh9	359	14	spread	spread	VBN
cord-008530-yni0poh9	359	15	of	of	IN
cord-008530-yni0poh9	359	16	the	the	DT
cord-008530-yni0poh9	359	17	virus	virus	NN
cord-008530-yni0poh9	359	18	from	from	IN
cord-008530-yni0poh9	359	19	the	the	DT
cord-008530-yni0poh9	359	20	infiltrating	infiltrate	VBG
cord-008530-yni0poh9	359	21	infected	infected	JJ
cord-008530-yni0poh9	359	22	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	359	23	.	.	.
cord-008530-yni0poh9	360	1	As	as	IN
cord-008530-yni0poh9	360	2	discussed	discuss	VBN
cord-008530-yni0poh9	360	3	above	above	RB
cord-008530-yni0poh9	360	4	,	,	,
cord-008530-yni0poh9	360	5	resident	resident	NN
cord-008530-yni0poh9	360	6	cells	cell	NNS
cord-008530-yni0poh9	360	7	of	of	IN
cord-008530-yni0poh9	360	8	the	the	DT
cord-008530-yni0poh9	360	9	CNS	CNS	NNP
cord-008530-yni0poh9	360	10	are	be	VBP
cord-008530-yni0poh9	360	11	well	well	RB
cord-008530-yni0poh9	360	12	endowed	endowed	JJ
cord-008530-yni0poh9	360	13	with	with	IN
cord-008530-yni0poh9	360	14	a	a	DT
cord-008530-yni0poh9	360	15	variety	variety	NN
cord-008530-yni0poh9	360	16	of	of	IN
cord-008530-yni0poh9	360	17	different	different	JJ
cord-008530-yni0poh9	360	18	chemokine	chemokine	NN
cord-008530-yni0poh9	360	19	receptors	receptor	NNS
cord-008530-yni0poh9	360	20	.	.	.
cord-008530-yni0poh9	361	1	The	the	DT
cord-008530-yni0poh9	361	2	levels	level	NNS
cord-008530-yni0poh9	361	3	and	and	CC
cord-008530-yni0poh9	361	4	type	type	NN
cord-008530-yni0poh9	361	5	of	of	IN
cord-008530-yni0poh9	361	6	coreceptot	coreceptot	JJ
cord-008530-yni0poh9	361	7	expression	expression	NN
cord-008530-yni0poh9	361	8	are	be	VBP
cord-008530-yni0poh9	361	9	likely	likely	JJ
cord-008530-yni0poh9	361	10	to	to	TO
cord-008530-yni0poh9	361	11	be	be	VB
cord-008530-yni0poh9	361	12	pivotal	pivotal	JJ
cord-008530-yni0poh9	361	13	determinants	determinant	NNS
cord-008530-yni0poh9	361	14	of	of	IN
cord-008530-yni0poh9	361	15	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	361	16	tropism	tropism	NN
cord-008530-yni0poh9	361	17	in	in	IN
cord-008530-yni0poh9	361	18	the	the	DT
cord-008530-yni0poh9	361	19	brain	brain	NN
cord-008530-yni0poh9	361	20	.	.	.
cord-008530-yni0poh9	362	1	The	the	DT
cord-008530-yni0poh9	362	2	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	362	3	for	for	IN
cord-008530-yni0poh9	362	4	M	M	NNP
cord-008530-yni0poh9	362	5	-	-	HYPH
cord-008530-yni0poh9	362	6	tropic	tropic	JJ
cord-008530-yni0poh9	362	7	variants	variant	NNS
cord-008530-yni0poh9	362	8	of	of	IN
cord-008530-yni0poh9	362	9	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	362	10	,	,	,
cord-008530-yni0poh9	362	11	CCR5	CCR5	NNP
cord-008530-yni0poh9	362	12	,	,	,
cord-008530-yni0poh9	362	13	CCR3	CCR3	NNP
cord-008530-yni0poh9	362	14	,	,	,
cord-008530-yni0poh9	362	15	and	and	CC
cord-008530-yni0poh9	362	16	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	362	17	are	be	VBP
cord-008530-yni0poh9	362	18	expressed	express	VBN
cord-008530-yni0poh9	362	19	by	by	IN
cord-008530-yni0poh9	362	20	microglia	microglia	NNS
cord-008530-yni0poh9	362	21	(	(	-LRB-
cord-008530-yni0poh9	362	22	He	-PRON-	PRP
cord-008530-yni0poh9	362	23	et	et	FW
cord-008530-yni0poh9	362	24	al	al	NNP
cord-008530-yni0poh9	362	25	.	.	NNP
cord-008530-yni0poh9	362	26	,	,	,
cord-008530-yni0poh9	362	27	1997	1997	CD
cord-008530-yni0poh9	362	28	;	;	:
cord-008530-yni0poh9	362	29	Lavi	Lavi	NNP
cord-008530-yni0poh9	362	30	et	et	NNP
cord-008530-yni0poh9	362	31	al	al	NNP
cord-008530-yni0poh9	362	32	.	.	NNP
cord-008530-yni0poh9	362	33	,	,	,
cord-008530-yni0poh9	362	34	1997	1997	CD
cord-008530-yni0poh9	362	35	;	;	:
cord-008530-yni0poh9	362	36	Vallat	Vallat	NNP
cord-008530-yni0poh9	362	37	et	et	NNP
cord-008530-yni0poh9	362	38	al	al	NNP
cord-008530-yni0poh9	362	39	.	.	NNP
cord-008530-yni0poh9	362	40	,	,	,
cord-008530-yni0poh9	362	41	1998	1998	CD
cord-008530-yni0poh9	362	42	)	)	-RRB-
cord-008530-yni0poh9	362	43	.	.	.
cord-008530-yni0poh9	363	1	Studies	study	NNS
cord-008530-yni0poh9	363	2	with	with	IN
cord-008530-yni0poh9	363	3	primary	primary	JJ
cord-008530-yni0poh9	363	4	cultures	culture	NNS
cord-008530-yni0poh9	363	5	of	of	IN
cord-008530-yni0poh9	363	6	human	human	JJ
cord-008530-yni0poh9	363	7	microglia	microglia	NNS
cord-008530-yni0poh9	363	8	have	have	VBP
cord-008530-yni0poh9	363	9	shown	show	VBN
cord-008530-yni0poh9	363	10	that	that	IN
cord-008530-yni0poh9	363	11	CCR5	CCR5	NNP
cord-008530-yni0poh9	363	12	and	and	CC
cord-008530-yni0poh9	363	13	CCR3	CCR3	NNP
cord-008530-yni0poh9	363	14	can	can	MD
cord-008530-yni0poh9	363	15	serve	serve	VB
cord-008530-yni0poh9	363	16	as	as	IN
cord-008530-yni0poh9	363	17	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	363	18	with	with	IN
cord-008530-yni0poh9	363	19	CD4	CD4	NNP
cord-008530-yni0poh9	363	20	for	for	IN
cord-008530-yni0poh9	363	21	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	363	22	infection	infection	NN
cord-008530-yni0poh9	363	23	,	,	,
cord-008530-yni0poh9	363	24	while	while	IN
cord-008530-yni0poh9	363	25	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	363	26	is	be	VBZ
cord-008530-yni0poh9	363	27	relatively	relatively	RB
cord-008530-yni0poh9	363	28	ineffective	ineffective	JJ
cord-008530-yni0poh9	363	29	in	in	IN
cord-008530-yni0poh9	363	30	this	this	DT
cord-008530-yni0poh9	363	31	capacity	capacity	NN
cord-008530-yni0poh9	363	32	.	.	.
cord-008530-yni0poh9	364	1	Microglia	Microglia	NNP
cord-008530-yni0poh9	364	2	have	have	VBP
cord-008530-yni0poh9	364	3	very	very	RB
cord-008530-yni0poh9	364	4	low	low	JJ
cord-008530-yni0poh9	364	5	surface	surface	NN
cord-008530-yni0poh9	364	6	-	-	HYPH
cord-008530-yni0poh9	364	7	expressed	express	VBN
cord-008530-yni0poh9	364	8	CD4	CD4	NNP
cord-008530-yni0poh9	364	9	(	(	-LRB-
cord-008530-yni0poh9	364	10	Buttini	Buttini	NNP
cord-008530-yni0poh9	364	11	et	et	NNP
cord-008530-yni0poh9	364	12	al	al	NNP
cord-008530-yni0poh9	364	13	.	.	NNP
cord-008530-yni0poh9	364	14	,	,	,
cord-008530-yni0poh9	364	15	1998	1998	CD
cord-008530-yni0poh9	364	16	)	)	-RRB-
cord-008530-yni0poh9	364	17	and	and	CC
cord-008530-yni0poh9	364	18	this	this	DT
cord-008530-yni0poh9	364	19	may	may	MD
cord-008530-yni0poh9	364	20	thus	thus	RB
cord-008530-yni0poh9	364	21	preclude	preclude	VB
cord-008530-yni0poh9	364	22	the	the	DT
cord-008530-yni0poh9	364	23	efficient	efficient	JJ
cord-008530-yni0poh9	364	24	use	use	NN
cord-008530-yni0poh9	364	25	of	of	IN
cord-008530-yni0poh9	364	26	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	364	27	as	as	IN
cord-008530-yni0poh9	364	28	a	a	DT
cord-008530-yni0poh9	364	29	coreceptor	coreceptor	NN
cord-008530-yni0poh9	364	30	.	.	.
cord-008530-yni0poh9	365	1	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	365	2	infection	infection	NN
cord-008530-yni0poh9	365	3	of	of	IN
cord-008530-yni0poh9	365	4	microglial	microglial	JJ
cord-008530-yni0poh9	365	5	cultures	culture	NNS
cord-008530-yni0poh9	365	6	can	can	MD
cord-008530-yni0poh9	365	7	be	be	VB
cord-008530-yni0poh9	365	8	inhibited	inhibit	VBN
cord-008530-yni0poh9	365	9	by	by	IN
cord-008530-yni0poh9	365	10	the	the	DT
cord-008530-yni0poh9	365	11	cognate	cognate	JJ
cord-008530-yni0poh9	365	12	ligands	ligand	NNS
cord-008530-yni0poh9	365	13	MIP	MIP	NNP
cord-008530-yni0poh9	365	14	-	-	HYPH
cord-008530-yni0poh9	365	15	I~	I~	NNP
cord-008530-yni0poh9	365	16	(	(	-LRB-
cord-008530-yni0poh9	365	17	CCR5	CCR5	NNP
cord-008530-yni0poh9	365	18	)	)	-RRB-
cord-008530-yni0poh9	365	19	and	and	CC
cord-008530-yni0poh9	365	20	eotaxin	eotaxin	NNP
cord-008530-yni0poh9	365	21	(	(	-LRB-
cord-008530-yni0poh9	365	22	CCR3	CCR3	NNP
cord-008530-yni0poh9	365	23	)	)	-RRB-
cord-008530-yni0poh9	365	24	,	,	,
cord-008530-yni0poh9	365	25	further	further	RB
cord-008530-yni0poh9	365	26	verifying	verify	VBG
cord-008530-yni0poh9	365	27	the	the	DT
cord-008530-yni0poh9	365	28	key	key	JJ
cord-008530-yni0poh9	365	29	role	role	NN
cord-008530-yni0poh9	365	30	of	of	IN
cord-008530-yni0poh9	365	31	the	the	DT
cord-008530-yni0poh9	365	32	microglial	microglial	NN
cord-008530-yni0poh9	365	33	-	-	HYPH
cord-008530-yni0poh9	365	34	expressed	express	VBN
cord-008530-yni0poh9	365	35	CC	cc	NN
cord-008530-yni0poh9	365	36	-	-	HYPH
cord-008530-yni0poh9	365	37	chemokine	chemokine	NN
cord-008530-yni0poh9	365	38	receptors	receptor	NNS
cord-008530-yni0poh9	365	39	for	for	IN
cord-008530-yni0poh9	365	40	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	365	41	entry	entry	NN
cord-008530-yni0poh9	365	42	into	into	IN
cord-008530-yni0poh9	365	43	cells	cell	NNS
cord-008530-yni0poh9	365	44	.	.	.
cord-008530-yni0poh9	366	1	Interestingly	interestingly	RB
cord-008530-yni0poh9	366	2	,	,	,
cord-008530-yni0poh9	366	3	the	the	DT
cord-008530-yni0poh9	366	4	use	use	NN
cord-008530-yni0poh9	366	5	of	of	IN
cord-008530-yni0poh9	366	6	both	both	CC
cord-008530-yni0poh9	366	7	CCR3	CCR3	NNP
cord-008530-yni0poh9	366	8	and	and	CC
cord-008530-yni0poh9	366	9	CCR5	CCR5	NNP
cord-008530-yni0poh9	366	10	for	for	IN
cord-008530-yni0poh9	366	11	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	366	12	infection	infection	NN
cord-008530-yni0poh9	366	13	of	of	IN
cord-008530-yni0poh9	366	14	microglia	microglia	JJ
cord-008530-yni0poh9	366	15	contrasts	contrast	NNS
cord-008530-yni0poh9	366	16	with	with	IN
cord-008530-yni0poh9	366	17	blood	blood	NN
cord-008530-yni0poh9	366	18	-	-	HYPH
cord-008530-yni0poh9	366	19	derived	derive	VBN
cord-008530-yni0poh9	366	20	macrophages	macrophage	NNS
cord-008530-yni0poh9	366	21	in	in	IN
cord-008530-yni0poh9	366	22	which	which	WDT
cord-008530-yni0poh9	366	23	CCR5	CCR5	NNP
cord-008530-yni0poh9	366	24	,	,	,
cord-008530-yni0poh9	366	25	but	but	CC
cord-008530-yni0poh9	366	26	not	not	RB
cord-008530-yni0poh9	366	27	CCR3	CCR3	NNP
cord-008530-yni0poh9	366	28	,	,	,
cord-008530-yni0poh9	366	29	functions	function	VBZ
cord-008530-yni0poh9	366	30	as	as	IN
cord-008530-yni0poh9	366	31	a	a	DT
cord-008530-yni0poh9	366	32	coreceptor	coreceptor	NN
cord-008530-yni0poh9	367	1	(	(	-LRB-
cord-008530-yni0poh9	367	2	Alkhatib	Alkhatib	NNP
cord-008530-yni0poh9	367	3	et	et	NNP
cord-008530-yni0poh9	367	4	al	al	NNP
cord-008530-yni0poh9	367	5	.	.	.
cord-008530-yni0poh9	368	1	,	,	,
cord-008530-yni0poh9	368	2	1996	1996	CD
cord-008530-yni0poh9	368	3	;	;	:
cord-008530-yni0poh9	368	4	Deng	Deng	NNP
cord-008530-yni0poh9	368	5	et	et	FW
cord-008530-yni0poh9	368	6	al	al	NNP
cord-008530-yni0poh9	368	7	.	.	.
cord-008530-yni0poh9	369	1	,	,	,
cord-008530-yni0poh9	369	2	1996	1996	CD
cord-008530-yni0poh9	369	3	;	;	:
cord-008530-yni0poh9	369	4	Wu	Wu	NNP
cord-008530-yni0poh9	369	5	et	et	NNP
cord-008530-yni0poh9	369	6	al	al	NNP
cord-008530-yni0poh9	369	7	.	.	NNP
cord-008530-yni0poh9	369	8	,	,	,
cord-008530-yni0poh9	369	9	1997	1997	CD
cord-008530-yni0poh9	369	10	)	)	-RRB-
cord-008530-yni0poh9	369	11	.	.	.
cord-008530-yni0poh9	370	1	This	this	DT
cord-008530-yni0poh9	370	2	suggests	suggest	VBZ
cord-008530-yni0poh9	370	3	that	that	IN
cord-008530-yni0poh9	370	4	M	M	NNP
cord-008530-yni0poh9	370	5	-	-	HYPH
cord-008530-yni0poh9	370	6	tropic	tropic	NNP
cord-008530-yni0poh9	370	7	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	370	8	variants	variant	NNS
cord-008530-yni0poh9	370	9	may	may	MD
cord-008530-yni0poh9	370	10	arise	arise	VB
cord-008530-yni0poh9	370	11	in	in	IN
cord-008530-yni0poh9	370	12	the	the	DT
cord-008530-yni0poh9	370	13	brain	brain	NN
cord-008530-yni0poh9	370	14	that	that	WDT
cord-008530-yni0poh9	370	15	have	have	VBP
cord-008530-yni0poh9	370	16	distinct	distinct	JJ
cord-008530-yni0poh9	370	17	coreceptor	coreceptor	NN
cord-008530-yni0poh9	370	18	requirements	requirement	NNS
cord-008530-yni0poh9	370	19	.	.	.
cord-008530-yni0poh9	371	1	In	in	IN
cord-008530-yni0poh9	371	2	support	support	NN
cord-008530-yni0poh9	371	3	of	of	IN
cord-008530-yni0poh9	371	4	this	this	DT
cord-008530-yni0poh9	371	5	,	,	,
cord-008530-yni0poh9	371	6	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	371	7	in	in	IN
cord-008530-yni0poh9	371	8	the	the	DT
cord-008530-yni0poh9	371	9	brain	brain	NN
cord-008530-yni0poh9	371	10	is	be	VBZ
cord-008530-yni0poh9	371	11	typically	typically	RB
cord-008530-yni0poh9	371	12	M	M	NNP
cord-008530-yni0poh9	371	13	-	-	HYPH
cord-008530-yni0poh9	371	14	tropic	tropic	NNP
cord-008530-yni0poh9	372	1	(	(	-LRB-
cord-008530-yni0poh9	372	2	Korber	Korber	NNP
cord-008530-yni0poh9	372	3	et	et	NNP
cord-008530-yni0poh9	372	4	al	al	NNP
cord-008530-yni0poh9	372	5	.	.	.
cord-008530-yni0poh9	373	1	,	,	,
cord-008530-yni0poh9	373	2	1994	1994	CD
cord-008530-yni0poh9	373	3	;	;	:
cord-008530-yni0poh9	373	4	Power	Power	NNP
cord-008530-yni0poh9	373	5	et	et	NNP
cord-008530-yni0poh9	373	6	al	al	NNP
cord-008530-yni0poh9	373	7	.	.	NNP
cord-008530-yni0poh9	373	8	,	,	,
cord-008530-yni0poh9	373	9	1994	1994	CD
cord-008530-yni0poh9	373	10	)	)	-RRB-
cord-008530-yni0poh9	373	11	.	.	.
cord-008530-yni0poh9	374	1	Moreover	moreover	RB
cord-008530-yni0poh9	374	2	,	,	,
cord-008530-yni0poh9	374	3	He	-PRON-	PRP
cord-008530-yni0poh9	374	4	and	and	CC
cord-008530-yni0poh9	374	5	colleagues	colleague	NNS
cord-008530-yni0poh9	374	6	(	(	-LRB-
cord-008530-yni0poh9	374	7	1997	1997	CD
cord-008530-yni0poh9	374	8	)	)	-RRB-
cord-008530-yni0poh9	374	9	demonstrated	demonstrate	VBD
cord-008530-yni0poh9	374	10	that	that	IN
cord-008530-yni0poh9	374	11	YU2	YU2	NNP
cord-008530-yni0poh9	374	12	and	and	CC
cord-008530-yni0poh9	374	13	JRL	JRL	NNP
cord-008530-yni0poh9	374	14	Env	Env	NNP
cord-008530-yni0poh9	374	15	proteins	protein	NNS
cord-008530-yni0poh9	374	16	that	that	WDT
cord-008530-yni0poh9	374	17	are	be	VBP
cord-008530-yni0poh9	374	18	cloned	clone	VBN
cord-008530-yni0poh9	374	19	directly	directly	RB
cord-008530-yni0poh9	374	20	from	from	IN
cord-008530-yni0poh9	374	21	HIV	HIV	NNP
cord-008530-yni0poh9	374	22	-	-	HYPH
cord-008530-yni0poh9	374	23	l	l	NNP
cord-008530-yni0poh9	374	24	-	-	HYPH
cord-008530-yni0poh9	374	25	infected	infect	VBN
cord-008530-yni0poh9	374	26	brain	brain	NN
cord-008530-yni0poh9	374	27	use	use	NN
cord-008530-yni0poh9	374	28	CCR5	CCR5	NNP
cord-008530-yni0poh9	374	29	or	or	CC
cord-008530-yni0poh9	374	30	CCR3	CCR3	NNP
cord-008530-yni0poh9	374	31	,	,	,
cord-008530-yni0poh9	374	32	together	together	RB
cord-008530-yni0poh9	374	33	with	with	IN
cord-008530-yni0poh9	374	34	CD4	CD4	NNP
cord-008530-yni0poh9	374	35	,	,	,
cord-008530-yni0poh9	374	36	for	for	IN
cord-008530-yni0poh9	374	37	virus	virus	NN
cord-008530-yni0poh9	374	38	entry	entry	NN
cord-008530-yni0poh9	374	39	into	into	IN
cord-008530-yni0poh9	374	40	transfected	transfected	JJ
cord-008530-yni0poh9	374	41	cells	cell	NNS
cord-008530-yni0poh9	374	42	.	.	.
cord-008530-yni0poh9	375	1	A	a	DT
cord-008530-yni0poh9	375	2	further	further	JJ
cord-008530-yni0poh9	375	3	determinant	determinant	NN
cord-008530-yni0poh9	375	4	of	of	IN
cord-008530-yni0poh9	375	5	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	375	6	entry	entry	NN
cord-008530-yni0poh9	375	7	and	and	CC
cord-008530-yni0poh9	375	8	infection	infection	NN
cord-008530-yni0poh9	375	9	in	in	IN
cord-008530-yni0poh9	375	10	the	the	DT
cord-008530-yni0poh9	375	11	CNS	CNS	NNP
cord-008530-yni0poh9	375	12	may	may	MD
cord-008530-yni0poh9	375	13	be	be	VB
cord-008530-yni0poh9	375	14	the	the	DT
cord-008530-yni0poh9	375	15	chemokines	chemokine	NNS
cord-008530-yni0poh9	375	16	themselves	-PRON-	PRP
cord-008530-yni0poh9	375	17	.	.	.
cord-008530-yni0poh9	376	1	Increased	increase	VBN
cord-008530-yni0poh9	376	2	levels	level	NNS
cord-008530-yni0poh9	376	3	of	of	IN
cord-008530-yni0poh9	376	4	MIP	MIP	NNP
cord-008530-yni0poh9	376	5	-	-	HYPH
cord-008530-yni0poh9	376	6	la	la	NNP
cord-008530-yni0poh9	376	7	,	,	,
cord-008530-yni0poh9	376	8	MIP	MIP	NNP
cord-008530-yni0poh9	376	9	-	-	HYPH
cord-008530-yni0poh9	376	10	I~	I~	NNP
cord-008530-yni0poh9	376	11	,	,	,
cord-008530-yni0poh9	376	12	RANTES	RANTES	NNP
cord-008530-yni0poh9	376	13	,	,	,
cord-008530-yni0poh9	376	14	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	376	15	,	,	,
cord-008530-yni0poh9	376	16	IP-10	IP-10	NNP
cord-008530-yni0poh9	376	17	,	,	,
cord-008530-yni0poh9	376	18	and	and	CC
cord-008530-yni0poh9	376	19	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	376	20	have	have	VBP
cord-008530-yni0poh9	376	21	been	be	VBN
cord-008530-yni0poh9	376	22	reported	report	VBN
cord-008530-yni0poh9	376	23	in	in	IN
cord-008530-yni0poh9	376	24	the	the	DT
cord-008530-yni0poh9	376	25	brain	brain	NN
cord-008530-yni0poh9	376	26	or	or	CC
cord-008530-yni0poh9	376	27	the	the	DT
cord-008530-yni0poh9	376	28	CSF	CSF	NNP
cord-008530-yni0poh9	376	29	of	of	IN
cord-008530-yni0poh9	376	30	individuals	individual	NNS
cord-008530-yni0poh9	376	31	with	with	IN
cord-008530-yni0poh9	376	32	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	377	1	(	(	-LRB-
cord-008530-yni0poh9	377	2	Conant	Conant	NNP
cord-008530-yni0poh9	377	3	et	et	NNP
cord-008530-yni0poh9	377	4	al	al	NNP
cord-008530-yni0poh9	377	5	.	.	NNP
cord-008530-yni0poh9	377	6	,	,	,
cord-008530-yni0poh9	377	7	1998	1998	CD
cord-008530-yni0poh9	377	8	;	;	:
cord-008530-yni0poh9	378	1	Kelder	Kelder	NNP
cord-008530-yni0poh9	378	2	et	et	NNP
cord-008530-yni0poh9	378	3	al	al	NNP
cord-008530-yni0poh9	378	4	.	.	NNP
cord-008530-yni0poh9	378	5	,	,	,
cord-008530-yni0poh9	378	6	1998	1998	CD
cord-008530-yni0poh9	378	7	;	;	:
cord-008530-yni0poh9	378	8	Kolb	Kolb	NNP
cord-008530-yni0poh9	378	9	et	et	NNP
cord-008530-yni0poh9	378	10	al	al	NNP
cord-008530-yni0poh9	378	11	.	.	.
cord-008530-yni0poh9	379	1	,	,	,
cord-008530-yni0poh9	379	2	1999	1999	CD
cord-008530-yni0poh9	379	3	;	;	:
cord-008530-yni0poh9	379	4	Letendre	Letendre	NNP
cord-008530-yni0poh9	379	5	et	et	NNP
cord-008530-yni0poh9	379	6	al	al	NNP
cord-008530-yni0poh9	379	7	.	.	NNP
cord-008530-yni0poh9	379	8	,	,	,
cord-008530-yni0poh9	379	9	1999	1999	CD
cord-008530-yni0poh9	379	10	;	;	:
cord-008530-yni0poh9	379	11	Sanders	Sanders	NNP
cord-008530-yni0poh9	379	12	et	et	NNP
cord-008530-yni0poh9	379	13	al	al	NNP
cord-008530-yni0poh9	379	14	.	.	NNP
cord-008530-yni0poh9	379	15	,	,	,
cord-008530-yni0poh9	379	16	1998	1998	CD
cord-008530-yni0poh9	379	17	;	;	:
cord-008530-yni0poh9	380	1	Schmidtmayerova	Schmidtmayerova	NNP
cord-008530-yni0poh9	380	2	et	et	NNP
cord-008530-yni0poh9	380	3	al	al	NNP
cord-008530-yni0poh9	380	4	.	.	.
cord-008530-yni0poh9	381	1	,	,	,
cord-008530-yni0poh9	381	2	1996	1996	CD
cord-008530-yni0poh9	381	3	;	;	:
cord-008530-yni0poh9	381	4	Zheng	Zheng	NNP
cord-008530-yni0poh9	381	5	et	et	NNP
cord-008530-yni0poh9	381	6	al	al	NNP
cord-008530-yni0poh9	381	7	.	.	NNP
cord-008530-yni0poh9	381	8	,	,	,
cord-008530-yni0poh9	381	9	1999b	1999b	CD
cord-008530-yni0poh9	381	10	)	)	-RRB-
cord-008530-yni0poh9	381	11	.	.	.
cord-008530-yni0poh9	382	1	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	382	2	may	may	MD
cord-008530-yni0poh9	382	3	directly	directly	RB
cord-008530-yni0poh9	382	4	regulate	regulate	VB
cord-008530-yni0poh9	382	5	the	the	DT
cord-008530-yni0poh9	382	6	expression	expression	NN
cord-008530-yni0poh9	382	7	of	of	IN
cord-008530-yni0poh9	382	8	these	these	DT
cord-008530-yni0poh9	382	9	chemokines	chemokine	NNS
cord-008530-yni0poh9	382	10	.	.	.
cord-008530-yni0poh9	383	1	Thus	thus	RB
cord-008530-yni0poh9	383	2	,	,	,
cord-008530-yni0poh9	383	3	infection	infection	NN
cord-008530-yni0poh9	383	4	of	of	IN
cord-008530-yni0poh9	383	5	cultured	cultured	JJ
cord-008530-yni0poh9	383	6	microglia	microglia	NNS
cord-008530-yni0poh9	383	7	and/or	and/or	CC
cord-008530-yni0poh9	383	8	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	383	9	markedly	markedly	RB
cord-008530-yni0poh9	383	10	increases	increase	VBZ
cord-008530-yni0poh9	383	11	the	the	DT
cord-008530-yni0poh9	383	12	expression	expression	NN
cord-008530-yni0poh9	383	13	of	of	IN
cord-008530-yni0poh9	383	14	MIP	MIP	NNP
cord-008530-yni0poh9	383	15	-	-	HYPH
cord-008530-yni0poh9	383	16	la	la	NNP
cord-008530-yni0poh9	383	17	and	and	CC
cord-008530-yni0poh9	383	18	MIP	MIP	NNP
cord-008530-yni0poh9	383	19	-	-	HYPH
cord-008530-yni0poh9	383	20	I~	I~	NNP
cord-008530-yni0poh9	384	1	(	(	-LRB-
cord-008530-yni0poh9	384	2	Schmidtmayerova	Schmidtmayerova	NNP
cord-008530-yni0poh9	384	3	et	et	NNP
cord-008530-yni0poh9	384	4	al	al	NNP
cord-008530-yni0poh9	384	5	.	.	NNP
cord-008530-yni0poh9	384	6	,	,	,
cord-008530-yni0poh9	384	7	1996	1996	CD
cord-008530-yni0poh9	384	8	)	)	-RRB-
cord-008530-yni0poh9	384	9	,	,	,
cord-008530-yni0poh9	384	10	while	while	IN
cord-008530-yni0poh9	384	11	expression	expression	NN
cord-008530-yni0poh9	384	12	of	of	IN
cord-008530-yni0poh9	384	13	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	384	14	RNA	RNA	NNP
cord-008530-yni0poh9	384	15	decreases	decrease	VBZ
cord-008530-yni0poh9	384	16	in	in	IN
cord-008530-yni0poh9	384	17	HIV	HIV	NNP
cord-008530-yni0poh9	384	18	-	-	HYPH
cord-008530-yni0poh9	384	19	l	l	NN
cord-008530-yni0poh9	384	20	-	-	HYPH
cord-008530-yni0poh9	384	21	infected	infect	VBN
cord-008530-yni0poh9	384	22	microglia	microglia	NNS
cord-008530-yni0poh9	384	23	but	but	CC
cord-008530-yni0poh9	384	24	increases	increase	NNS
cord-008530-yni0poh9	384	25	in	in	IN
cord-008530-yni0poh9	384	26	similarly	similarly	RB
cord-008530-yni0poh9	384	27	infected	infect	VBN
cord-008530-yni0poh9	384	28	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	384	29	(	(	-LRB-
cord-008530-yni0poh9	385	1	Zheng	Zheng	NNP
cord-008530-yni0poh9	385	2	et	et	NNP
cord-008530-yni0poh9	385	3	al	al	NNP
cord-008530-yni0poh9	385	4	.	.	NNP
cord-008530-yni0poh9	385	5	,	,	,
cord-008530-yni0poh9	385	6	1999b	1999b	CD
cord-008530-yni0poh9	385	7	)	)	-RRB-
cord-008530-yni0poh9	385	8	.	.	.
cord-008530-yni0poh9	386	1	In	in	IN
cord-008530-yni0poh9	386	2	recent	recent	JJ
cord-008530-yni0poh9	386	3	unpublished	unpublished	JJ
cord-008530-yni0poh9	386	4	studies	study	NNS
cord-008530-yni0poh9	386	5	,	,	,
cord-008530-yni0poh9	386	6	we	-PRON-	PRP
cord-008530-yni0poh9	386	7	have	have	VBP
cord-008530-yni0poh9	386	8	observed	observe	VBN
cord-008530-yni0poh9	386	9	induction	induction	NN
cord-008530-yni0poh9	386	10	of	of	IN
cord-008530-yni0poh9	386	11	IP-10	IP-10	NNP
cord-008530-yni0poh9	386	12	gene	gene	NN
cord-008530-yni0poh9	386	13	expression	expression	NN
cord-008530-yni0poh9	386	14	in	in	IN
cord-008530-yni0poh9	386	15	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	386	16	in	in	IN
cord-008530-yni0poh9	386	17	the	the	DT
cord-008530-yni0poh9	386	18	brain	brain	NN
cord-008530-yni0poh9	386	19	of	of	IN
cord-008530-yni0poh9	386	20	transgenic	transgenic	JJ
cord-008530-yni0poh9	386	21	mice	mouse	NNS
cord-008530-yni0poh9	386	22	with	with	IN
cord-008530-yni0poh9	386	23	astrocyte	astrocyte	RB
cord-008530-yni0poh9	386	24	-	-	HYPH
cord-008530-yni0poh9	386	25	targeted	target	VBN
cord-008530-yni0poh9	386	26	expression	expression	NN
cord-008530-yni0poh9	386	27	of	of	IN
cord-008530-yni0poh9	386	28	HIVgpl20	HIVgpl20	NNP
cord-008530-yni0poh9	386	29	.	.	.
cord-008530-yni0poh9	387	1	These	these	DT
cord-008530-yni0poh9	387	2	transgenic	transgenic	JJ
cord-008530-yni0poh9	387	3	mice	mouse	NNS
cord-008530-yni0poh9	387	4	exhibit	exhibit	VBP
cord-008530-yni0poh9	387	5	similar	similar	JJ
cord-008530-yni0poh9	387	6	neurodegenerative	neurodegenerative	JJ
cord-008530-yni0poh9	387	7	and	and	CC
cord-008530-yni0poh9	387	8	other	other	JJ
cord-008530-yni0poh9	387	9	pathologic	pathologic	JJ
cord-008530-yni0poh9	387	10	changes	change	NNS
cord-008530-yni0poh9	387	11	(	(	-LRB-
cord-008530-yni0poh9	387	12	e.g.	e.g.	RB
cord-008530-yni0poh9	387	13	,	,	,
cord-008530-yni0poh9	387	14	astrocytosis	astrocytosis	NNP
cord-008530-yni0poh9	387	15	)	)	-RRB-
cord-008530-yni0poh9	387	16	to	to	IN
cord-008530-yni0poh9	387	17	neu	neu	NNP
cord-008530-yni0poh9	387	18	-	-	HYPH
cord-008530-yni0poh9	387	19	roAIDS	roAIDS	NNP
cord-008530-yni0poh9	388	1	(	(	-LRB-
cord-008530-yni0poh9	388	2	Toggas	Toggas	NNP
cord-008530-yni0poh9	388	3	et	et	NNP
cord-008530-yni0poh9	388	4	al	al	NNP
cord-008530-yni0poh9	388	5	.	.	NNP
cord-008530-yni0poh9	388	6	,	,	,
cord-008530-yni0poh9	388	7	1994	1994	CD
cord-008530-yni0poh9	388	8	)	)	-RRB-
cord-008530-yni0poh9	389	1	--our	--our	:
cord-008530-yni0poh9	389	2	findings	finding	NNS
cord-008530-yni0poh9	389	3	suggest	suggest	VBP
cord-008530-yni0poh9	389	4	that	that	IN
cord-008530-yni0poh9	389	5	a	a	DT
cord-008530-yni0poh9	389	6	further	further	JJ
cord-008530-yni0poh9	389	7	action	action	NN
cord-008530-yni0poh9	389	8	of	of	IN
cord-008530-yni0poh9	389	9	HIVgpl20	HIVgpl20	NNP
cord-008530-yni0poh9	389	10	is	be	VBZ
cord-008530-yni0poh9	389	11	the	the	DT
cord-008530-yni0poh9	389	12	induction	induction	NN
cord-008530-yni0poh9	389	13	of	of	IN
cord-008530-yni0poh9	389	14	IP-10	IP-10	NNP
cord-008530-yni0poh9	389	15	.	.	.
cord-008530-yni0poh9	390	1	The	the	DT
cord-008530-yni0poh9	390	2	CNS	CNS	NNP
cord-008530-yni0poh9	390	3	expression	expression	NN
cord-008530-yni0poh9	390	4	of	of	IN
cord-008530-yni0poh9	390	5	IP-10	IP-10	NNP
cord-008530-yni0poh9	390	6	and	and	CC
cord-008530-yni0poh9	390	7	other	other	JJ
cord-008530-yni0poh9	390	8	chemokines	chemokine	NNS
cord-008530-yni0poh9	390	9	,	,	,
cord-008530-yni0poh9	390	10	such	such	JJ
cord-008530-yni0poh9	390	11	as	as	IN
cord-008530-yni0poh9	390	12	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	390	13	,	,	,
cord-008530-yni0poh9	390	14	correlates	correlate	VBZ
cord-008530-yni0poh9	390	15	with	with	IN
cord-008530-yni0poh9	390	16	viral	viral	JJ
cord-008530-yni0poh9	390	17	load	load	NN
cord-008530-yni0poh9	390	18	and	and	CC
cord-008530-yni0poh9	390	19	increases	increase	NNS
cord-008530-yni0poh9	390	20	with	with	IN
cord-008530-yni0poh9	390	21	the	the	DT
cord-008530-yni0poh9	390	22	progression	progression	NN
cord-008530-yni0poh9	390	23	of	of	IN
cord-008530-yni0poh9	390	24	brain	brain	NN
cord-008530-yni0poh9	390	25	injury	injury	NN
cord-008530-yni0poh9	390	26	,	,	,
cord-008530-yni0poh9	390	27	indicating	indicate	VBG
cord-008530-yni0poh9	390	28	a	a	DT
cord-008530-yni0poh9	390	29	possible	possible	JJ
cord-008530-yni0poh9	390	30	role	role	NN
cord-008530-yni0poh9	390	31	for	for	IN
cord-008530-yni0poh9	390	32	these	these	DT
cord-008530-yni0poh9	390	33	chemokines	chemokine	NNS
cord-008530-yni0poh9	390	34	in	in	IN
cord-008530-yni0poh9	390	35	the	the	DT
cord-008530-yni0poh9	390	36	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	390	37	of	of	IN
cord-008530-yni0poh9	390	38	neuroAIDS	neuroaids	FW
cord-008530-yni0poh9	390	39	(	(	-LRB-
cord-008530-yni0poh9	390	40	Kelder	Kelder	NNP
cord-008530-yni0poh9	390	41	et	et	NNP
cord-008530-yni0poh9	390	42	al	al	NNP
cord-008530-yni0poh9	390	43	.	.	NNP
cord-008530-yni0poh9	390	44	,	,	,
cord-008530-yni0poh9	390	45	1998	1998	CD
cord-008530-yni0poh9	390	46	;	;	:
cord-008530-yni0poh9	391	1	Kolb	Kolb	NNP
cord-008530-yni0poh9	391	2	et	et	NNP
cord-008530-yni0poh9	391	3	al	al	NNP
cord-008530-yni0poh9	391	4	.	.	NNP
cord-008530-yni0poh9	391	5	,	,	,
cord-008530-yni0poh9	391	6	1999	1999	CD
cord-008530-yni0poh9	391	7	)	)	-RRB-
cord-008530-yni0poh9	391	8	.	.	.
cord-008530-yni0poh9	392	1	Other	other	JJ
cord-008530-yni0poh9	392	2	than	than	IN
cord-008530-yni0poh9	392	3	their	-PRON-	PRP$
cord-008530-yni0poh9	392	4	potential	potential	JJ
cord-008530-yni0poh9	392	5	contribution	contribution	NN
cord-008530-yni0poh9	392	6	to	to	IN
cord-008530-yni0poh9	392	7	brain	brain	NN
cord-008530-yni0poh9	392	8	injury	injury	NN
cord-008530-yni0poh9	392	9	(	(	-LRB-
cord-008530-yni0poh9	392	10	discussed	discuss	VBN
cord-008530-yni0poh9	392	11	in	in	IN
cord-008530-yni0poh9	392	12	more	more	JJR
cord-008530-yni0poh9	392	13	detail	detail	NN
cord-008530-yni0poh9	392	14	below	below	IN
cord-008530-yni0poh9	392	15	)	)	-RRB-
cord-008530-yni0poh9	392	16	,	,	,
cord-008530-yni0poh9	392	17	the	the	DT
cord-008530-yni0poh9	392	18	increased	increase	VBN
cord-008530-yni0poh9	392	19	presence	presence	NN
cord-008530-yni0poh9	392	20	of	of	IN
cord-008530-yni0poh9	392	21	these	these	DT
cord-008530-yni0poh9	392	22	chemokines	chemokine	NNS
cord-008530-yni0poh9	392	23	in	in	IN
cord-008530-yni0poh9	392	24	the	the	DT
cord-008530-yni0poh9	392	25	CNS	CNS	NNP
cord-008530-yni0poh9	392	26	during	during	IN
cord-008530-yni0poh9	392	27	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	392	28	infection	infection	NN
cord-008530-yni0poh9	392	29	may	may	MD
cord-008530-yni0poh9	392	30	promote	promote	VB
cord-008530-yni0poh9	392	31	,	,	,
cord-008530-yni0poh9	392	32	via	via	IN
cord-008530-yni0poh9	392	33	their	-PRON-	PRP$
cord-008530-yni0poh9	392	34	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	392	35	activity	activity	NN
cord-008530-yni0poh9	392	36	,	,	,
cord-008530-yni0poh9	392	37	the	the	DT
cord-008530-yni0poh9	392	38	further	further	JJ
cord-008530-yni0poh9	392	39	recruitment	recruitment	NN
cord-008530-yni0poh9	392	40	and	and	CC
cord-008530-yni0poh9	392	41	accumulation	accumulation	NN
cord-008530-yni0poh9	392	42	of	of	IN
cord-008530-yni0poh9	392	43	T	t	NN
cord-008530-yni0poh9	392	44	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	392	45	and	and	CC
cord-008530-yni0poh9	392	46	macrophages	macrophage	NNS
cord-008530-yni0poh9	392	47	in	in	IN
cord-008530-yni0poh9	392	48	the	the	DT
cord-008530-yni0poh9	392	49	brain	brain	NN
cord-008530-yni0poh9	392	50	.	.	.
cord-008530-yni0poh9	393	1	In	in	IN
cord-008530-yni0poh9	393	2	support	support	NN
cord-008530-yni0poh9	393	3	of	of	IN
cord-008530-yni0poh9	393	4	this	this	DT
cord-008530-yni0poh9	393	5	idea	idea	NN
cord-008530-yni0poh9	393	6	,	,	,
cord-008530-yni0poh9	393	7	HIV	HIV	NNP
cord-008530-yni0poh9	393	8	-	-	HYPH
cord-008530-yni0poh9	393	9	Tat	Tat	NNP
cord-008530-yni0poh9	393	10	,	,	,
cord-008530-yni0poh9	393	11	protein	protein	NN
cord-008530-yni0poh9	393	12	-	-	HYPH
cord-008530-yni0poh9	393	13	induced	induce	VBN
cord-008530-yni0poh9	393	14	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	393	15	expression	expression	NN
cord-008530-yni0poh9	393	16	by	by	IN
cord-008530-yni0poh9	393	17	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	393	18	can	can	MD
cord-008530-yni0poh9	393	19	stimulate	stimulate	VB
cord-008530-yni0poh9	393	20	the	the	DT
cord-008530-yni0poh9	393	21	transmigration	transmigration	NN
cord-008530-yni0poh9	393	22	of	of	IN
cord-008530-yni0poh9	393	23	monocytes	monocyte	NNS
cord-008530-yni0poh9	393	24	across	across	IN
cord-008530-yni0poh9	393	25	an	an	DT
cord-008530-yni0poh9	393	26	in	in	FW
cord-008530-yni0poh9	393	27	vitro	vitro	FW
cord-008530-yni0poh9	393	28	model	model	NN
cord-008530-yni0poh9	393	29	of	of	IN
cord-008530-yni0poh9	393	30	the	the	DT
cord-008530-yni0poh9	393	31	human	human	JJ
cord-008530-yni0poh9	393	32	BBB	BBB	NNP
cord-008530-yni0poh9	393	33	(	(	-LRB-
cord-008530-yni0poh9	393	34	Weiss	Weiss	NNP
cord-008530-yni0poh9	393	35	et	et	NNP
cord-008530-yni0poh9	393	36	al	al	NNP
cord-008530-yni0poh9	393	37	.	.	NNP
cord-008530-yni0poh9	393	38	,	,	,
cord-008530-yni0poh9	393	39	1999	1999	CD
cord-008530-yni0poh9	393	40	)	)	-RRB-
cord-008530-yni0poh9	393	41	.	.	.
cord-008530-yni0poh9	394	1	Finally	finally	RB
cord-008530-yni0poh9	394	2	,	,	,
cord-008530-yni0poh9	394	3	since	since	IN
cord-008530-yni0poh9	394	4	MIP	MIP	NNP
cord-008530-yni0poh9	394	5	-	-	HYPH
cord-008530-yni0poh9	394	6	la	la	NNP
cord-008530-yni0poh9	394	7	and	and	CC
cord-008530-yni0poh9	394	8	RANTES	RANTES	NNP
cord-008530-yni0poh9	394	9	can	can	MD
cord-008530-yni0poh9	394	10	effectively	effectively	RB
cord-008530-yni0poh9	394	11	inhibit	inhibit	VB
cord-008530-yni0poh9	394	12	CCR5	CCR5	NNP
cord-008530-yni0poh9	394	13	coreceptor	coreceptor	NN
cord-008530-yni0poh9	394	14	-	-	HYPH
cord-008530-yni0poh9	394	15	mediated	mediate	VBN
cord-008530-yni0poh9	394	16	cell	cell	NN
cord-008530-yni0poh9	394	17	entry	entry	NN
cord-008530-yni0poh9	394	18	by	by	IN
cord-008530-yni0poh9	394	19	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	395	1	(	(	-LRB-
cord-008530-yni0poh9	395	2	Cocchi	Cocchi	NNP
cord-008530-yni0poh9	395	3	et	et	FW
cord-008530-yni0poh9	395	4	al	al	NNP
cord-008530-yni0poh9	395	5	.	.	.
cord-008530-yni0poh9	396	1	,	,	,
cord-008530-yni0poh9	396	2	1996	1996	CD
cord-008530-yni0poh9	396	3	;	;	:
cord-008530-yni0poh9	396	4	Dragic	Dragic	NNP
cord-008530-yni0poh9	396	5	et	et	NNP
cord-008530-yni0poh9	396	6	al	al	NNP
cord-008530-yni0poh9	396	7	.	.	.
cord-008530-yni0poh9	397	1	,	,	,
cord-008530-yni0poh9	397	2	1996	1996	CD
cord-008530-yni0poh9	397	3	)	)	-RRB-
cord-008530-yni0poh9	397	4	,	,	,
cord-008530-yni0poh9	397	5	expression	expression	NN
cord-008530-yni0poh9	397	6	of	of	IN
cord-008530-yni0poh9	397	7	these	these	DT
cord-008530-yni0poh9	397	8	and	and	CC
cord-008530-yni0poh9	397	9	other	other	JJ
cord-008530-yni0poh9	397	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	397	11	in	in	IN
cord-008530-yni0poh9	397	12	the	the	DT
cord-008530-yni0poh9	397	13	CNS	CNS	NNP
cord-008530-yni0poh9	397	14	in	in	IN
cord-008530-yni0poh9	397	15	neu	neu	NNP
cord-008530-yni0poh9	397	16	-	-	HYPH
cord-008530-yni0poh9	397	17	roAIDS	roAIDS	NNP
cord-008530-yni0poh9	397	18	might	may	MD
cord-008530-yni0poh9	397	19	limit	limit	VB
cord-008530-yni0poh9	397	20	the	the	DT
cord-008530-yni0poh9	397	21	spread	spread	NN
cord-008530-yni0poh9	397	22	of	of	IN
cord-008530-yni0poh9	397	23	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	397	24	by	by	IN
cord-008530-yni0poh9	397	25	antagonizing	antagonize	VBG
cord-008530-yni0poh9	397	26	infection	infection	NN
cord-008530-yni0poh9	397	27	of	of	IN
cord-008530-yni0poh9	397	28	target	target	NN
cord-008530-yni0poh9	397	29	microglia	microglia	NNS
cord-008530-yni0poh9	397	30	.	.	.
cord-008530-yni0poh9	398	1	The	the	DT
cord-008530-yni0poh9	398	2	wide	wide	JJ
cord-008530-yni0poh9	398	3	distribution	distribution	NN
cord-008530-yni0poh9	398	4	of	of	IN
cord-008530-yni0poh9	398	5	chemokine	chemokine	NN
cord-008530-yni0poh9	398	6	receptors	receptor	NNS
cord-008530-yni0poh9	398	7	in	in	IN
cord-008530-yni0poh9	398	8	the	the	DT
cord-008530-yni0poh9	398	9	normal	normal	JJ
cord-008530-yni0poh9	398	10	and	and	CC
cord-008530-yni0poh9	398	11	HIV	HIV	NNP
cord-008530-yni0poh9	398	12	-	-	HYPH
cord-008530-yni0poh9	398	13	infected	infect	VBN
cord-008530-yni0poh9	398	14	human	human	JJ
cord-008530-yni0poh9	398	15	brain	brain	NN
cord-008530-yni0poh9	398	16	,	,	,
cord-008530-yni0poh9	398	17	as	as	RB
cord-008530-yni0poh9	398	18	well	well	RB
cord-008530-yni0poh9	398	19	as	as	IN
cord-008530-yni0poh9	398	20	the	the	DT
cord-008530-yni0poh9	398	21	increased	increase	VBN
cord-008530-yni0poh9	398	22	expression	expression	NN
cord-008530-yni0poh9	398	23	of	of	IN
cord-008530-yni0poh9	398	24	their	-PRON-	PRP$
cord-008530-yni0poh9	398	25	cognate	cognate	JJ
cord-008530-yni0poh9	398	26	ligands	ligand	NNS
cord-008530-yni0poh9	398	27	,	,	,
cord-008530-yni0poh9	398	28	not	not	RB
cord-008530-yni0poh9	398	29	only	only	RB
cord-008530-yni0poh9	398	30	provides	provide	VBZ
cord-008530-yni0poh9	398	31	an	an	DT
cord-008530-yni0poh9	398	32	avenue	avenue	NN
cord-008530-yni0poh9	398	33	for	for	IN
cord-008530-yni0poh9	398	34	HIV	HIV	NNP
cord-008530-yni0poh9	398	35	entry	entry	NN
cord-008530-yni0poh9	398	36	into	into	IN
cord-008530-yni0poh9	398	37	the	the	DT
cord-008530-yni0poh9	398	38	brain	brain	NN
cord-008530-yni0poh9	398	39	via	via	IN
cord-008530-yni0poh9	398	40	the	the	DT
cord-008530-yni0poh9	398	41	microglia	microglia	NN
cord-008530-yni0poh9	398	42	,	,	,
cord-008530-yni0poh9	398	43	but	but	CC
cord-008530-yni0poh9	398	44	might	may	MD
cord-008530-yni0poh9	398	45	also	also	RB
cord-008530-yni0poh9	398	46	contribute	contribute	VB
cord-008530-yni0poh9	398	47	to	to	IN
cord-008530-yni0poh9	398	48	the	the	DT
cord-008530-yni0poh9	398	49	neuronal	neuronal	JJ
cord-008530-yni0poh9	398	50	injury	injury	NN
cord-008530-yni0poh9	398	51	and	and	CC
cord-008530-yni0poh9	398	52	loss	loss	NN
cord-008530-yni0poh9	398	53	that	that	DT
cord-008530-yni0poh9	398	54	ensue	ensue	NN
cord-008530-yni0poh9	398	55	.	.	.
cord-008530-yni0poh9	399	1	As	as	IN
cord-008530-yni0poh9	399	2	indicated	indicate	VBN
cord-008530-yni0poh9	399	3	above	above	RB
cord-008530-yni0poh9	399	4	,	,	,
cord-008530-yni0poh9	399	5	current	current	JJ
cord-008530-yni0poh9	399	6	evidence	evidence	NN
cord-008530-yni0poh9	399	7	supports	support	VBZ
cord-008530-yni0poh9	399	8	the	the	DT
cord-008530-yni0poh9	399	9	idea	idea	NN
cord-008530-yni0poh9	399	10	that	that	IN
cord-008530-yni0poh9	399	11	neuronal	neuronal	JJ
cord-008530-yni0poh9	399	12	injury	injury	NN
cord-008530-yni0poh9	399	13	and	and	CC
cord-008530-yni0poh9	399	14	death	death	NN
cord-008530-yni0poh9	399	15	in	in	IN
cord-008530-yni0poh9	399	16	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	399	17	are	be	VBP
cord-008530-yni0poh9	399	18	consequences	consequence	NNS
cord-008530-yni0poh9	399	19	of	of	IN
cord-008530-yni0poh9	399	20	indirect	indirect	JJ
cord-008530-yni0poh9	399	21	mechanisms	mechanism	NNS
cord-008530-yni0poh9	399	22	involving	involve	VBG
cord-008530-yni0poh9	399	23	a	a	DT
cord-008530-yni0poh9	399	24	variety	variety	NN
cord-008530-yni0poh9	399	25	of	of	IN
cord-008530-yni0poh9	399	26	host	host	NN
cord-008530-yni0poh9	399	27	-	-	HYPH
cord-008530-yni0poh9	399	28	derived	derive	VBN
cord-008530-yni0poh9	399	29	molecules	molecule	NNS
cord-008530-yni0poh9	399	30	for	for	IN
cord-008530-yni0poh9	399	31	example	example	NN
cord-008530-yni0poh9	399	32	,	,	,
cord-008530-yni0poh9	399	33	cytokines	cytokine	NNS
cord-008530-yni0poh9	399	34	and	and	CC
cord-008530-yni0poh9	399	35	excitotoxic	excitotoxic	JJ
cord-008530-yni0poh9	399	36	amino	amino	NN
cord-008530-yni0poh9	399	37	acids	acid	NNS
cord-008530-yni0poh9	399	38	or	or	CC
cord-008530-yni0poh9	399	39	HIVencoded	hivencode	VBN
cord-008530-yni0poh9	399	40	factors	factor	NNS
cord-008530-yni0poh9	399	41	such	such	JJ
cord-008530-yni0poh9	399	42	as	as	IN
cord-008530-yni0poh9	399	43	gpl20	gpl20	CD
cord-008530-yni0poh9	399	44	;	;	:
cord-008530-yni0poh9	399	45	it	-PRON-	PRP
cord-008530-yni0poh9	399	46	is	be	VBZ
cord-008530-yni0poh9	399	47	probable	probable	JJ
cord-008530-yni0poh9	399	48	that	that	IN
cord-008530-yni0poh9	399	49	the	the	DT
cord-008530-yni0poh9	399	50	host	host	NN
cord-008530-yni0poh9	399	51	and	and	CC
cord-008530-yni0poh9	399	52	viral	viral	JJ
cord-008530-yni0poh9	399	53	products	product	NNS
cord-008530-yni0poh9	399	54	work	work	VBP
cord-008530-yni0poh9	399	55	in	in	IN
cord-008530-yni0poh9	399	56	combination	combination	NN
cord-008530-yni0poh9	399	57	.	.	.
cord-008530-yni0poh9	400	1	Loss	loss	NN
cord-008530-yni0poh9	400	2	of	of	IN
cord-008530-yni0poh9	400	3	neurons	neuron	NNS
cord-008530-yni0poh9	400	4	,	,	,
cord-008530-yni0poh9	400	5	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	400	6	,	,	,
cord-008530-yni0poh9	400	7	and	and	CC
cord-008530-yni0poh9	400	8	microglia	microglia	NNS
cord-008530-yni0poh9	400	9	through	through	IN
cord-008530-yni0poh9	400	10	apoptosis	apoptosis	NN
cord-008530-yni0poh9	400	11	appears	appear	VBZ
cord-008530-yni0poh9	400	12	to	to	TO
cord-008530-yni0poh9	400	13	be	be	VB
cord-008530-yni0poh9	400	14	prominent	prominent	JJ
cord-008530-yni0poh9	400	15	in	in	IN
cord-008530-yni0poh9	400	16	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	401	1	(	(	-LRB-
cord-008530-yni0poh9	401	2	Adle	Adle	NNP
cord-008530-yni0poh9	401	3	-	-	HYPH
cord-008530-yni0poh9	401	4	Biassette	Biassette	NNP
cord-008530-yni0poh9	401	5	et	et	NNP
cord-008530-yni0poh9	401	6	al	al	NNP
cord-008530-yni0poh9	401	7	.	.	.
cord-008530-yni0poh9	402	1	,	,	,
cord-008530-yni0poh9	402	2	1995	1995	CD
cord-008530-yni0poh9	402	3	;	;	:
cord-008530-yni0poh9	402	4	Gelbard	Gelbard	NNP
cord-008530-yni0poh9	402	5	et	et	NNP
cord-008530-yni0poh9	402	6	al	al	NNP
cord-008530-yni0poh9	402	7	.	.	NNP
cord-008530-yni0poh9	402	8	,	,	,
cord-008530-yni0poh9	402	9	1995	1995	CD
cord-008530-yni0poh9	402	10	;	;	:
cord-008530-yni0poh9	402	11	Shiet	Shiet	NNP
cord-008530-yni0poh9	402	12	al	al	NNP
cord-008530-yni0poh9	402	13	.	.	NNP
cord-008530-yni0poh9	402	14	,	,	,
cord-008530-yni0poh9	402	15	1996	1996	CD
cord-008530-yni0poh9	402	16	)	)	-RRB-
cord-008530-yni0poh9	402	17	and	and	CC
cord-008530-yni0poh9	402	18	can	can	MD
cord-008530-yni0poh9	402	19	be	be	VB
cord-008530-yni0poh9	402	20	induced	induce	VBN
cord-008530-yni0poh9	402	21	by	by	IN
cord-008530-yni0poh9	402	22	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	402	23	infection	infection	NN
cord-008530-yni0poh9	402	24	of	of	IN
cord-008530-yni0poh9	402	25	these	these	DT
cord-008530-yni0poh9	402	26	cells	cell	NNS
cord-008530-yni0poh9	402	27	in	in	IN
cord-008530-yni0poh9	402	28	vitro	vitro	FW
cord-008530-yni0poh9	402	29	(	(	-LRB-
cord-008530-yni0poh9	402	30	Shi	Shi	NNP
cord-008530-yni0poh9	402	31	et	et	FW
cord-008530-yni0poh9	402	32	al	al	NNP
cord-008530-yni0poh9	402	33	.	.	NNP
cord-008530-yni0poh9	402	34	,	,	,
cord-008530-yni0poh9	402	35	1996	1996	CD
cord-008530-yni0poh9	402	36	)	)	-RRB-
cord-008530-yni0poh9	402	37	.	.	.
cord-008530-yni0poh9	403	1	Analysis	analysis	NN
cord-008530-yni0poh9	403	2	of	of	IN
cord-008530-yni0poh9	403	3	a	a	DT
cord-008530-yni0poh9	403	4	panel	panel	NN
cord-008530-yni0poh9	403	5	of	of	IN
cord-008530-yni0poh9	403	6	diverse	diverse	JJ
cord-008530-yni0poh9	403	7	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	403	8	primary	primary	JJ
cord-008530-yni0poh9	403	9	isolates	isolate	NNS
cord-008530-yni0poh9	403	10	or	or	CC
cord-008530-yni0poh9	403	11	strains	strain	NNS
cord-008530-yni0poh9	403	12	revealed	reveal	VBD
cord-008530-yni0poh9	403	13	that	that	IN
cord-008530-yni0poh9	403	14	,	,	,
cord-008530-yni0poh9	403	15	compared	compare	VBN
cord-008530-yni0poh9	403	16	with	with	IN
cord-008530-yni0poh9	403	17	blood	blood	NN
cord-008530-yni0poh9	403	18	-	-	HYPH
cord-008530-yni0poh9	403	19	derived	derive	VBN
cord-008530-yni0poh9	403	20	or	or	CC
cord-008530-yni0poh9	403	21	T	T	NNP
cord-008530-yni0poh9	403	22	-	-	HYPH
cord-008530-yni0poh9	403	23	tropic	tropic	NNP
cord-008530-yni0poh9	403	24	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	403	25	isolates	isolate	VBZ
cord-008530-yni0poh9	403	26	,	,	,
cord-008530-yni0poh9	403	27	brain	brain	NN
cord-008530-yni0poh9	403	28	-	-	HYPH
cord-008530-yni0poh9	403	29	derived	derive	VBN
cord-008530-yni0poh9	403	30	M	M	NNP
cord-008530-yni0poh9	403	31	-	-	HYPH
cord-008530-yni0poh9	403	32	tropic	tropic	NNP
cord-008530-yni0poh9	403	33	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	403	34	isolates	isolate	NNS
cord-008530-yni0poh9	403	35	are	be	VBP
cord-008530-yni0poh9	403	36	ineffective	ineffective	JJ
cord-008530-yni0poh9	403	37	at	at	IN
cord-008530-yni0poh9	403	38	inducing	induce	VBG
cord-008530-yni0poh9	403	39	neuronal	neuronal	JJ
cord-008530-yni0poh9	403	40	and	and	CC
cord-008530-yni0poh9	403	41	astrocyte	astrocyte	NN
cord-008530-yni0poh9	404	1	apoptosis	apoptosis	NN
cord-008530-yni0poh9	404	2	(	(	-LRB-
cord-008530-yni0poh9	405	1	Ohagen	Ohagen	NNP
cord-008530-yni0poh9	405	2	et	et	NNP
cord-008530-yni0poh9	405	3	al	al	NNP
cord-008530-yni0poh9	405	4	.	.	NNP
cord-008530-yni0poh9	405	5	,	,	,
cord-008530-yni0poh9	405	6	1999	1999	CD
cord-008530-yni0poh9	406	1	;	;	:
cord-008530-yni0poh9	406	2	Zheng	Zheng	NNP
cord-008530-yni0poh9	406	3	et	et	NNP
cord-008530-yni0poh9	406	4	al	al	NNP
cord-008530-yni0poh9	406	5	.	.	NNP
cord-008530-yni0poh9	406	6	,	,	,
cord-008530-yni0poh9	406	7	1999b	1999b	CD
cord-008530-yni0poh9	406	8	)	)	-RRB-
cord-008530-yni0poh9	406	9	.	.	.
cord-008530-yni0poh9	407	1	Thus	thus	RB
cord-008530-yni0poh9	407	2	,	,	,
cord-008530-yni0poh9	407	3	the	the	DT
cord-008530-yni0poh9	407	4	primary	primary	JJ
cord-008530-yni0poh9	407	5	determinant	determinant	NN
cord-008530-yni0poh9	407	6	of	of	IN
cord-008530-yni0poh9	407	7	neurodegeneration	neurodegeneration	NN
cord-008530-yni0poh9	407	8	may	may	MD
cord-008530-yni0poh9	407	9	not	not	RB
cord-008530-yni0poh9	407	10	be	be	VB
cord-008530-yni0poh9	407	11	the	the	DT
cord-008530-yni0poh9	407	12	M	M	NNP
cord-008530-yni0poh9	407	13	-	-	HYPH
cord-008530-yni0poh9	407	14	tropic	tropic	NNP
cord-008530-yni0poh9	407	15	HIV	HIV	NNP
cord-008530-yni0poh9	407	16	forms	form	NNS
cord-008530-yni0poh9	407	17	constituting	constitute	VBG
cord-008530-yni0poh9	407	18	the	the	DT
cord-008530-yni0poh9	407	19	major	major	JJ
cord-008530-yni0poh9	407	20	CNS	CNS	NNP
cord-008530-yni0poh9	407	21	reservoir	reservoir	NN
cord-008530-yni0poh9	407	22	of	of	IN
cord-008530-yni0poh9	407	23	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	407	24	,	,	,
cord-008530-yni0poh9	407	25	but	but	CC
cord-008530-yni0poh9	407	26	rather	rather	RB
cord-008530-yni0poh9	407	27	,	,	,
cord-008530-yni0poh9	407	28	it	-PRON-	PRP
cord-008530-yni0poh9	407	29	resides	reside	VBZ
cord-008530-yni0poh9	407	30	with	with	IN
cord-008530-yni0poh9	407	31	blood	blood	NN
cord-008530-yni0poh9	407	32	-	-	HYPH
cord-008530-yni0poh9	407	33	derived	derive	VBN
cord-008530-yni0poh9	407	34	viruses	virus	NNS
cord-008530-yni0poh9	407	35	that	that	WDT
cord-008530-yni0poh9	407	36	are	be	VBP
cord-008530-yni0poh9	407	37	prominent	prominent	JJ
cord-008530-yni0poh9	407	38	during	during	IN
cord-008530-yni0poh9	407	39	later	later	JJ
cord-008530-yni0poh9	407	40	stages	stage	NNS
cord-008530-yni0poh9	407	41	of	of	IN
cord-008530-yni0poh9	407	42	disease	disease	NN
cord-008530-yni0poh9	407	43	.	.	.
cord-008530-yni0poh9	408	1	Furthermore	furthermore	RB
cord-008530-yni0poh9	408	2	,	,	,
cord-008530-yni0poh9	408	3	the	the	DT
cord-008530-yni0poh9	408	4	Env	Env	NNP
cord-008530-yni0poh9	408	5	V3	V3	NNP
cord-008530-yni0poh9	408	6	region	region	NN
cord-008530-yni0poh9	408	7	is	be	VBZ
cord-008530-yni0poh9	408	8	the	the	DT
cord-008530-yni0poh9	408	9	major	major	JJ
cord-008530-yni0poh9	408	10	determinant	determinant	NN
cord-008530-yni0poh9	408	11	of	of	IN
cord-008530-yni0poh9	408	12	neuronal	neuronal	JJ
cord-008530-yni0poh9	408	13	apoptosis	apoptosis	NN
cord-008530-yni0poh9	408	14	and	and	CC
cord-008530-yni0poh9	408	15	also	also	RB
cord-008530-yni0poh9	408	16	determines	determine	VBZ
cord-008530-yni0poh9	408	17	chemokine	chemokine	JJ
cord-008530-yni0poh9	408	18	coreceptor	coreceptor	NN
cord-008530-yni0poh9	408	19	usage	usage	NN
cord-008530-yni0poh9	408	20	for	for	IN
cord-008530-yni0poh9	408	21	infection	infection	NN
cord-008530-yni0poh9	408	22	(	(	-LRB-
cord-008530-yni0poh9	409	1	Ohagen	Ohagen	NNP
cord-008530-yni0poh9	409	2	et	et	NNP
cord-008530-yni0poh9	409	3	al	al	NNP
cord-008530-yni0poh9	409	4	.	.	NNP
cord-008530-yni0poh9	409	5	,	,	,
cord-008530-yni0poh9	409	6	1999	1999	CD
cord-008530-yni0poh9	409	7	)	)	-RRB-
cord-008530-yni0poh9	409	8	,	,	,
cord-008530-yni0poh9	409	9	implicating	implicate	VBG
cord-008530-yni0poh9	409	10	these	these	DT
cord-008530-yni0poh9	409	11	viral	viral	JJ
cord-008530-yni0poh9	409	12	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	409	13	in	in	IN
cord-008530-yni0poh9	409	14	the	the	DT
cord-008530-yni0poh9	409	15	effector	effector	JJ
cord-008530-yni0poh9	409	16	pathways	pathway	NNS
cord-008530-yni0poh9	409	17	that	that	WDT
cord-008530-yni0poh9	409	18	mediate	mediate	VBP
cord-008530-yni0poh9	409	19	neuronal	neuronal	JJ
cord-008530-yni0poh9	409	20	damage	damage	NN
cord-008530-yni0poh9	409	21	during	during	IN
cord-008530-yni0poh9	409	22	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	409	23	.	.	.
cord-008530-yni0poh9	410	1	As	as	IN
cord-008530-yni0poh9	410	2	mentioned	mention	VBN
cord-008530-yni0poh9	410	3	above	above	RB
cord-008530-yni0poh9	410	4	,	,	,
cord-008530-yni0poh9	410	5	the	the	DT
cord-008530-yni0poh9	410	6	blood	blood	NN
cord-008530-yni0poh9	410	7	-	-	HYPH
cord-008530-yni0poh9	410	8	derived	derive	VBN
cord-008530-yni0poh9	410	9	,	,	,
cord-008530-yni0poh9	410	10	T	T	NNP
cord-008530-yni0poh9	410	11	-	-	HYPH
cord-008530-yni0poh9	410	12	tropic	tropic	NNP
cord-008530-yni0poh9	410	13	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	410	14	isolates	isolate	NNS
cord-008530-yni0poh9	410	15	rely	rely	VBP
cord-008530-yni0poh9	410	16	primarily	primarily	RB
cord-008530-yni0poh9	410	17	on	on	IN
cord-008530-yni0poh9	410	18	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	410	19	as	as	IN
cord-008530-yni0poh9	410	20	a	a	DT
cord-008530-yni0poh9	410	21	coreceptor	coreceptor	NN
cord-008530-yni0poh9	410	22	,	,	,
cord-008530-yni0poh9	410	23	whereas	whereas	IN
cord-008530-yni0poh9	410	24	the	the	DT
cord-008530-yni0poh9	410	25	brain	brain	NN
cord-008530-yni0poh9	410	26	-	-	HYPH
cord-008530-yni0poh9	410	27	derived	derive	VBN
cord-008530-yni0poh9	410	28	,	,	,
cord-008530-yni0poh9	410	29	Mtropic	Mtropic	NNP
cord-008530-yni0poh9	410	30	isolates	isolate	VBZ
cord-008530-yni0poh9	410	31	use	use	VBP
cord-008530-yni0poh9	410	32	CCR5	CCR5	NNP
cord-008530-yni0poh9	410	33	and	and	CC
cord-008530-yni0poh9	410	34	CCR3	CCR3	NNP
cord-008530-yni0poh9	410	35	.	.	.
cord-008530-yni0poh9	411	1	In	in	IN
cord-008530-yni0poh9	411	2	view	view	NN
cord-008530-yni0poh9	411	3	of	of	IN
cord-008530-yni0poh9	411	4	the	the	DT
cord-008530-yni0poh9	411	5	congruity	congruity	NN
cord-008530-yni0poh9	411	6	between	between	IN
cord-008530-yni0poh9	411	7	the	the	DT
cord-008530-yni0poh9	411	8	induction	induction	NN
cord-008530-yni0poh9	411	9	of	of	IN
cord-008530-yni0poh9	411	10	neuronal	neuronal	JJ
cord-008530-yni0poh9	411	11	apoptosis	apoptosis	NN
cord-008530-yni0poh9	411	12	and	and	CC
cord-008530-yni0poh9	411	13	chemokine	chemokine	NN
cord-008530-yni0poh9	411	14	coreceptor	coreceptor	NN
cord-008530-yni0poh9	411	15	usage	usage	NN
cord-008530-yni0poh9	411	16	,	,	,
cord-008530-yni0poh9	411	17	and	and	CC
cord-008530-yni0poh9	411	18	the	the	DT
cord-008530-yni0poh9	411	19	fact	fact	NN
cord-008530-yni0poh9	411	20	that	that	IN
cord-008530-yni0poh9	411	21	neurons	neuron	NNS
cord-008530-yni0poh9	411	22	express	express	VBP
cord-008530-yni0poh9	411	23	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	411	24	(	(	-LRB-
cord-008530-yni0poh9	411	25	as	as	IN
cord-008530-yni0poh9	411	26	noted	note	VBN
cord-008530-yni0poh9	411	27	above	above	IN
cord-008530-yni0poh9	411	28	)	)	-RRB-
cord-008530-yni0poh9	411	29	,	,	,
cord-008530-yni0poh9	411	30	many	many	JJ
cord-008530-yni0poh9	411	31	recent	recent	JJ
cord-008530-yni0poh9	411	32	studies	study	NNS
cord-008530-yni0poh9	411	33	have	have	VBP
cord-008530-yni0poh9	411	34	focused	focus	VBN
cord-008530-yni0poh9	411	35	on	on	IN
cord-008530-yni0poh9	411	36	the	the	DT
cord-008530-yni0poh9	411	37	possible	possible	JJ
cord-008530-yni0poh9	411	38	role	role	NN
cord-008530-yni0poh9	411	39	of	of	IN
cord-008530-yni0poh9	411	40	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	411	41	in	in	IN
cord-008530-yni0poh9	411	42	mediating	mediate	VBG
cord-008530-yni0poh9	411	43	brain	brain	NN
cord-008530-yni0poh9	411	44	injury	injury	NN
cord-008530-yni0poh9	411	45	in	in	IN
cord-008530-yni0poh9	411	46	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	411	47	.	.	.
cord-008530-yni0poh9	412	1	Hesselgesser	hesselgesser	NN
cord-008530-yni0poh9	412	2	and	and	CC
cord-008530-yni0poh9	412	3	colleagues	colleague	NNS
cord-008530-yni0poh9	412	4	showed	show	VBD
cord-008530-yni0poh9	412	5	that	that	IN
cord-008530-yni0poh9	412	6	signaling	signal	VBG
cord-008530-yni0poh9	412	7	by	by	IN
cord-008530-yni0poh9	412	8	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	412	9	,	,	,
cord-008530-yni0poh9	412	10	following	follow	VBG
cord-008530-yni0poh9	412	11	the	the	DT
cord-008530-yni0poh9	412	12	binding	binding	NN
cord-008530-yni0poh9	412	13	of	of	IN
cord-008530-yni0poh9	412	14	T	T	NNP
cord-008530-yni0poh9	412	15	-	-	HYPH
cord-008530-yni0poh9	412	16	tropic	tropic	NNP
cord-008530-yni0poh9	412	17	HIVgpl20	HIVgpl20	NNP
cord-008530-yni0poh9	412	18	,	,	,
cord-008530-yni0poh9	412	19	activates	activate	VBZ
cord-008530-yni0poh9	412	20	apoptotic	apoptotic	JJ
cord-008530-yni0poh9	412	21	cell	cell	NN
cord-008530-yni0poh9	412	22	death	death	NN
cord-008530-yni0poh9	412	23	in	in	IN
cord-008530-yni0poh9	412	24	human	human	JJ
cord-008530-yni0poh9	412	25	hNT	hnt	NN
cord-008530-yni0poh9	412	26	neuronal	neuronal	JJ
cord-008530-yni0poh9	412	27	cells	cell	NNS
cord-008530-yni0poh9	412	28	(	(	-LRB-
cord-008530-yni0poh9	412	29	Hesselgesser	Hesselgesser	NNP
cord-008530-yni0poh9	412	30	et	et	FW
cord-008530-yni0poh9	412	31	al	al	NNP
cord-008530-yni0poh9	412	32	.	.	NNP
cord-008530-yni0poh9	412	33	,	,	,
cord-008530-yni0poh9	412	34	1998	1998	CD
cord-008530-yni0poh9	412	35	)	)	-RRB-
cord-008530-yni0poh9	412	36	.	.	.
cord-008530-yni0poh9	413	1	This	this	DT
cord-008530-yni0poh9	413	2	does	do	VBZ
cord-008530-yni0poh9	413	3	not	not	RB
cord-008530-yni0poh9	413	4	appear	appear	VB
cord-008530-yni0poh9	413	5	to	to	TO
cord-008530-yni0poh9	413	6	reflect	reflect	VB
cord-008530-yni0poh9	413	7	an	an	DT
cord-008530-yni0poh9	413	8	unusual	unusual	JJ
cord-008530-yni0poh9	413	9	property	property	NN
cord-008530-yni0poh9	413	10	of	of	IN
cord-008530-yni0poh9	413	11	hNT	hNT	NNP
cord-008530-yni0poh9	413	12	cells	cell	NNS
cord-008530-yni0poh9	413	13	,	,	,
cord-008530-yni0poh9	413	14	which	which	WDT
cord-008530-yni0poh9	413	15	have	have	VBP
cord-008530-yni0poh9	413	16	a	a	DT
cord-008530-yni0poh9	413	17	transformed	transform	VBN
cord-008530-yni0poh9	413	18	phenotype	phenotype	NN
cord-008530-yni0poh9	413	19	,	,	,
cord-008530-yni0poh9	413	20	as	as	IN
cord-008530-yni0poh9	413	21	induction	induction	NN
cord-008530-yni0poh9	413	22	of	of	IN
cord-008530-yni0poh9	413	23	apoptotic	apoptotic	JJ
cord-008530-yni0poh9	413	24	cell	cell	NN
cord-008530-yni0poh9	413	25	death	death	NN
cord-008530-yni0poh9	413	26	is	be	VBZ
cord-008530-yni0poh9	413	27	also	also	RB
cord-008530-yni0poh9	413	28	induced	induce	VBN
cord-008530-yni0poh9	413	29	in	in	IN
cord-008530-yni0poh9	413	30	rat	rat	NN
cord-008530-yni0poh9	413	31	hippocampal	hippocampal	JJ
cord-008530-yni0poh9	413	32	neurons	neuron	NNS
cord-008530-yni0poh9	413	33	exposed	expose	VBN
cord-008530-yni0poh9	413	34	to	to	IN
cord-008530-yni0poh9	413	35	HIVgpl20	HIVgpl20	NNP
cord-008530-yni0poh9	414	1	(	(	-LRB-
cord-008530-yni0poh9	414	2	Meucci	Meucci	NNP
cord-008530-yni0poh9	414	3	et	et	NNP
cord-008530-yni0poh9	414	4	al	al	NNP
cord-008530-yni0poh9	414	5	.	.	NNP
cord-008530-yni0poh9	414	6	,	,	,
cord-008530-yni0poh9	414	7	1998	1998	CD
cord-008530-yni0poh9	414	8	)	)	-RRB-
cord-008530-yni0poh9	414	9	.	.	.
cord-008530-yni0poh9	415	1	In	in	IN
cord-008530-yni0poh9	415	2	these	these	DT
cord-008530-yni0poh9	415	3	latter	latter	JJ
cord-008530-yni0poh9	415	4	experiments	experiment	NNS
cord-008530-yni0poh9	415	5	,	,	,
cord-008530-yni0poh9	415	6	pretreatment	pretreatment	NN
cord-008530-yni0poh9	415	7	of	of	IN
cord-008530-yni0poh9	415	8	the	the	DT
cord-008530-yni0poh9	415	9	neurons	neuron	NNS
cord-008530-yni0poh9	415	10	with	with	IN
cord-008530-yni0poh9	415	11	the	the	DT
cord-008530-yni0poh9	415	12	cognate	cognate	JJ
cord-008530-yni0poh9	415	13	ligand	ligand	NN
cord-008530-yni0poh9	415	14	for	for	IN
cord-008530-yni0poh9	415	15	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	415	16	,	,	,
cord-008530-yni0poh9	415	17	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	415	18	,	,	,
cord-008530-yni0poh9	415	19	partially	partially	RB
cord-008530-yni0poh9	415	20	protected	protect	VBN
cord-008530-yni0poh9	415	21	against	against	IN
cord-008530-yni0poh9	415	22	gpl20-induced	gpl20-induced	JJ
cord-008530-yni0poh9	415	23	neuronal	neuronal	JJ
cord-008530-yni0poh9	415	24	apoptosis	apoptosis	NN
cord-008530-yni0poh9	415	25	,	,	,
cord-008530-yni0poh9	415	26	suggesting	suggest	VBG
cord-008530-yni0poh9	415	27	that	that	IN
cord-008530-yni0poh9	415	28	the	the	DT
cord-008530-yni0poh9	415	29	effects	effect	NNS
cord-008530-yni0poh9	415	30	of	of	IN
cord-008530-yni0poh9	415	31	the	the	DT
cord-008530-yni0poh9	415	32	viral	viral	JJ
cord-008530-yni0poh9	415	33	product	product	NN
cord-008530-yni0poh9	415	34	are	be	VBP
cord-008530-yni0poh9	415	35	mediated	mediate	VBN
cord-008530-yni0poh9	415	36	,	,	,
cord-008530-yni0poh9	415	37	in	in	IN
cord-008530-yni0poh9	415	38	part	part	NN
cord-008530-yni0poh9	415	39	,	,	,
cord-008530-yni0poh9	415	40	by	by	IN
cord-008530-yni0poh9	415	41	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	415	42	binding	binding	NN
cord-008530-yni0poh9	415	43	.	.	.
cord-008530-yni0poh9	416	1	More	more	RBR
cord-008530-yni0poh9	416	2	recently	recently	RB
cord-008530-yni0poh9	416	3	,	,	,
cord-008530-yni0poh9	416	4	purified	purify	VBN
cord-008530-yni0poh9	416	5	virions	virion	NNS
cord-008530-yni0poh9	416	6	from	from	IN
cord-008530-yni0poh9	416	7	T	T	NNP
cord-008530-yni0poh9	416	8	-	-	HYPH
cord-008530-yni0poh9	416	9	tropic	tropic	NNP
cord-008530-yni0poh9	416	10	,	,	,
cord-008530-yni0poh9	416	11	but	but	CC
cord-008530-yni0poh9	416	12	not	not	RB
cord-008530-yni0poh9	416	13	M	M	NNP
cord-008530-yni0poh9	416	14	-	-	HYPH
cord-008530-yni0poh9	416	15	tropic	tropic	NNP
cord-008530-yni0poh9	416	16	,	,	,
cord-008530-yni0poh9	416	17	HIV	HIV	NNP
cord-008530-yni0poh9	416	18	isolates	isolate	NNS
cord-008530-yni0poh9	416	19	were	be	VBD
cord-008530-yni0poh9	416	20	shown	show	VBN
cord-008530-yni0poh9	416	21	to	to	TO
cord-008530-yni0poh9	416	22	induce	induce	VB
cord-008530-yni0poh9	416	23	CD4	CD4	NNP
cord-008530-yni0poh9	416	24	independent	independent	JJ
cord-008530-yni0poh9	416	25	neuronal	neuronal	JJ
cord-008530-yni0poh9	416	26	signaling	signaling	NN
cord-008530-yni0poh9	416	27	and	and	CC
cord-008530-yni0poh9	416	28	apopto	apopto	NNS
cord-008530-yni0poh9	416	29	-	-	HYPH
cord-008530-yni0poh9	416	30	sis	sis	NN
cord-008530-yni0poh9	416	31	that	that	WDT
cord-008530-yni0poh9	416	32	could	could	MD
cord-008530-yni0poh9	416	33	be	be	VB
cord-008530-yni0poh9	416	34	blocked	block	VBN
cord-008530-yni0poh9	416	35	by	by	IN
cord-008530-yni0poh9	416	36	antibodies	antibody	NNS
cord-008530-yni0poh9	416	37	to	to	IN
cord-008530-yni0poh9	416	38	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	417	1	(	(	-LRB-
cord-008530-yni0poh9	417	2	Zheng	Zheng	NNP
cord-008530-yni0poh9	417	3	et	et	NNP
cord-008530-yni0poh9	417	4	al	al	NNP
cord-008530-yni0poh9	417	5	.	.	NNP
cord-008530-yni0poh9	417	6	,	,	,
cord-008530-yni0poh9	417	7	1999a	1999a	CD
cord-008530-yni0poh9	417	8	)	)	-RRB-
cord-008530-yni0poh9	417	9	.	.	.
cord-008530-yni0poh9	418	1	In	in	IN
cord-008530-yni0poh9	418	2	these	these	DT
cord-008530-yni0poh9	418	3	studies	study	NNS
cord-008530-yni0poh9	418	4	,	,	,
cord-008530-yni0poh9	418	5	the	the	DT
cord-008530-yni0poh9	418	6	purified	purify	VBN
cord-008530-yni0poh9	418	7	T	T	NNP
cord-008530-yni0poh9	418	8	-	-	HYPH
cord-008530-yni0poh9	418	9	tropic	tropic	NNP
cord-008530-yni0poh9	418	10	HIVgpl20	HIVgpl20	NNP
cord-008530-yni0poh9	418	11	protein	protein	NN
cord-008530-yni0poh9	418	12	proved	prove	VBD
cord-008530-yni0poh9	418	13	to	to	TO
cord-008530-yni0poh9	418	14	be	be	VB
cord-008530-yni0poh9	418	15	far	far	RB
cord-008530-yni0poh9	418	16	less	less	RBR
cord-008530-yni0poh9	418	17	effective	effective	JJ
cord-008530-yni0poh9	418	18	in	in	IN
cord-008530-yni0poh9	418	19	affecting	affect	VBG
cord-008530-yni0poh9	418	20	neuronal	neuronal	JJ
cord-008530-yni0poh9	418	21	signaling	signaling	NN
cord-008530-yni0poh9	418	22	and	and	CC
cord-008530-yni0poh9	418	23	cell	cell	NN
cord-008530-yni0poh9	418	24	death	death	NN
cord-008530-yni0poh9	418	25	than	than	IN
cord-008530-yni0poh9	418	26	the	the	DT
cord-008530-yni0poh9	418	27	whole	whole	JJ
cord-008530-yni0poh9	418	28	virions	virion	NNS
cord-008530-yni0poh9	418	29	.	.	.
cord-008530-yni0poh9	419	1	Since	since	IN
cord-008530-yni0poh9	419	2	the	the	DT
cord-008530-yni0poh9	419	3	effects	effect	NNS
cord-008530-yni0poh9	419	4	of	of	IN
cord-008530-yni0poh9	419	5	the	the	DT
cord-008530-yni0poh9	419	6	virions	virion	NNS
cord-008530-yni0poh9	419	7	could	could	MD
cord-008530-yni0poh9	419	8	be	be	VB
cord-008530-yni0poh9	419	9	blocked	block	VBN
cord-008530-yni0poh9	419	10	by	by	IN
cord-008530-yni0poh9	419	11	antibodies	antibody	NNS
cord-008530-yni0poh9	419	12	to	to	IN
cord-008530-yni0poh9	419	13	gpl20	gpl20	CD
cord-008530-yni0poh9	419	14	and	and	CC
cord-008530-yni0poh9	419	15	gp41	gp41	NNP
cord-008530-yni0poh9	419	16	,	,	,
cord-008530-yni0poh9	419	17	the	the	DT
cord-008530-yni0poh9	419	18	findings	finding	NNS
cord-008530-yni0poh9	419	19	indicate	indicate	VBP
cord-008530-yni0poh9	419	20	that	that	IN
cord-008530-yni0poh9	419	21	the	the	DT
cord-008530-yni0poh9	419	22	envelope	envelope	NN
cord-008530-yni0poh9	419	23	proteins	protein	NNS
cord-008530-yni0poh9	419	24	in	in	IN
cord-008530-yni0poh9	419	25	their	-PRON-	PRP$
cord-008530-yni0poh9	419	26	native	native	JJ
cord-008530-yni0poh9	419	27	state	state	NN
cord-008530-yni0poh9	419	28	are	be	VBP
cord-008530-yni0poh9	419	29	more	more	RBR
cord-008530-yni0poh9	419	30	potent	potent	JJ
cord-008530-yni0poh9	419	31	mediators	mediator	NNS
cord-008530-yni0poh9	419	32	than	than	IN
cord-008530-yni0poh9	419	33	their	-PRON-	PRP$
cord-008530-yni0poh9	419	34	recombinant	recombinant	JJ
cord-008530-yni0poh9	419	35	or	or	CC
cord-008530-yni0poh9	419	36	purified	purify	VBN
cord-008530-yni0poh9	419	37	derivatives	derivative	NNS
cord-008530-yni0poh9	419	38	.	.	.
cord-008530-yni0poh9	420	1	In	in	IN
cord-008530-yni0poh9	420	2	all	all	DT
cord-008530-yni0poh9	420	3	,	,	,
cord-008530-yni0poh9	420	4	the	the	DT
cord-008530-yni0poh9	420	5	implication	implication	NN
cord-008530-yni0poh9	420	6	from	from	IN
cord-008530-yni0poh9	420	7	these	these	DT
cord-008530-yni0poh9	420	8	studies	study	NNS
cord-008530-yni0poh9	420	9	,	,	,
cord-008530-yni0poh9	420	10	which	which	WDT
cord-008530-yni0poh9	420	11	utilized	utilize	VBD
cord-008530-yni0poh9	420	12	either	either	CC
cord-008530-yni0poh9	420	13	human	human	JJ
cord-008530-yni0poh9	420	14	neuronal	neuronal	JJ
cord-008530-yni0poh9	420	15	cell	cell	NN
cord-008530-yni0poh9	420	16	lines	line	NNS
cord-008530-yni0poh9	420	17	or	or	CC
cord-008530-yni0poh9	420	18	highly	highly	RB
cord-008530-yni0poh9	420	19	purified	purify	VBN
cord-008530-yni0poh9	420	20	rodent	rodent	NN
cord-008530-yni0poh9	420	21	or	or	CC
cord-008530-yni0poh9	420	22	human	human	JJ
cord-008530-yni0poh9	420	23	primary	primary	JJ
cord-008530-yni0poh9	420	24	neuronal	neuronal	JJ
cord-008530-yni0poh9	420	25	cultures	culture	NNS
cord-008530-yni0poh9	420	26	,	,	,
cord-008530-yni0poh9	420	27	is	be	VBZ
cord-008530-yni0poh9	420	28	that	that	IN
cord-008530-yni0poh9	420	29	direct	direct	JJ
cord-008530-yni0poh9	420	30	binding	binding	NN
cord-008530-yni0poh9	420	31	of	of	IN
cord-008530-yni0poh9	420	32	HIV	HIV	NNP
cord-008530-yni0poh9	420	33	gpl20	gpl20	NNP
cord-008530-yni0poh9	420	34	to	to	IN
cord-008530-yni0poh9	420	35	the	the	DT
cord-008530-yni0poh9	420	36	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	420	37	found	find	VBN
cord-008530-yni0poh9	420	38	on	on	IN
cord-008530-yni0poh9	420	39	neurons	neuron	NNS
cord-008530-yni0poh9	420	40	activates	activate	VBZ
cord-008530-yni0poh9	420	41	apoptotic	apoptotic	JJ
cord-008530-yni0poh9	420	42	cell	cell	NN
cord-008530-yni0poh9	420	43	death	death	NN
cord-008530-yni0poh9	420	44	in	in	IN
cord-008530-yni0poh9	420	45	these	these	DT
cord-008530-yni0poh9	420	46	cells	cell	NNS
cord-008530-yni0poh9	420	47	.	.	.
cord-008530-yni0poh9	421	1	Contrary	contrary	JJ
cord-008530-yni0poh9	421	2	to	to	IN
cord-008530-yni0poh9	421	3	this	this	DT
cord-008530-yni0poh9	421	4	notion	notion	NN
cord-008530-yni0poh9	421	5	,	,	,
cord-008530-yni0poh9	421	6	in	in	IN
cord-008530-yni0poh9	421	7	mixed	mixed	JJ
cord-008530-yni0poh9	421	8	brain	brain	NN
cord-008530-yni0poh9	421	9	-	-	HYPH
cord-008530-yni0poh9	421	10	cell	cell	NN
cord-008530-yni0poh9	421	11	cultures	culture	NNS
cord-008530-yni0poh9	421	12	derived	derive	VBN
cord-008530-yni0poh9	421	13	from	from	IN
cord-008530-yni0poh9	421	14	embryonic	embryonic	JJ
cord-008530-yni0poh9	421	15	rat	rat	NN
cord-008530-yni0poh9	421	16	cerebrocortex	cerebrocortex	NNP
cord-008530-yni0poh9	421	17	,	,	,
cord-008530-yni0poh9	421	18	gpl20-induced	gpl20-induced	JJ
cord-008530-yni0poh9	421	19	neuronal	neuronal	JJ
cord-008530-yni0poh9	421	20	apoptosis	apoptosis	NN
cord-008530-yni0poh9	421	21	was	be	VBD
cord-008530-yni0poh9	421	22	completely	completely	RB
cord-008530-yni0poh9	421	23	blocked	block	VBN
cord-008530-yni0poh9	421	24	by	by	IN
cord-008530-yni0poh9	421	25	the	the	DT
cord-008530-yni0poh9	421	26	tripeptide	tripeptide	NN
cord-008530-yni0poh9	421	27	TKP	tkp	NN
cord-008530-yni0poh9	421	28	,	,	,
cord-008530-yni0poh9	421	29	which	which	WDT
cord-008530-yni0poh9	421	30	blocks	block	VBZ
cord-008530-yni0poh9	421	31	macrophages	macrophage	NNS
cord-008530-yni0poh9	421	32	microglial	microglial	JJ
cord-008530-yni0poh9	421	33	activation	activation	NN
cord-008530-yni0poh9	421	34	(	(	-LRB-
cord-008530-yni0poh9	421	35	Kaul	Kaul	NNP
cord-008530-yni0poh9	421	36	and	and	CC
cord-008530-yni0poh9	421	37	Lipton	Lipton	NNP
cord-008530-yni0poh9	421	38	,	,	,
cord-008530-yni0poh9	421	39	1999	1999	CD
cord-008530-yni0poh9	421	40	)	)	-RRB-
cord-008530-yni0poh9	421	41	.	.	.
cord-008530-yni0poh9	422	1	This	this	DT
cord-008530-yni0poh9	422	2	blockade	blockade	NN
cord-008530-yni0poh9	422	3	by	by	IN
cord-008530-yni0poh9	422	4	TKP	TKP	NNP
cord-008530-yni0poh9	422	5	was	be	VBD
cord-008530-yni0poh9	422	6	specific	specific	JJ
cord-008530-yni0poh9	422	7	for	for	IN
cord-008530-yni0poh9	422	8	gpl20	gpl20	NNP
cord-008530-yni0poh9	422	9	as	as	IN
cord-008530-yni0poh9	422	10	SDF	SDF	NNP
cord-008530-yni0poh9	422	11	-	-	HYPH
cord-008530-yni0poh9	422	12	l	l	NN
cord-008530-yni0poh9	422	13	-	-	HYPH
cord-008530-yni0poh9	422	14	induced	induce	VBN
cord-008530-yni0poh9	422	15	neuronal	neuronal	JJ
cord-008530-yni0poh9	422	16	apoptosis	apoptosis	NN
cord-008530-yni0poh9	422	17	(	(	-LRB-
cord-008530-yni0poh9	422	18	as	as	IN
cord-008530-yni0poh9	422	19	noted	note	VBN
cord-008530-yni0poh9	422	20	below	below	RB
cord-008530-yni0poh9	422	21	)	)	-RRB-
cord-008530-yni0poh9	422	22	was	be	VBD
cord-008530-yni0poh9	422	23	unaffected	unaffected	JJ
cord-008530-yni0poh9	422	24	by	by	IN
cord-008530-yni0poh9	422	25	the	the	DT
cord-008530-yni0poh9	422	26	peptide	peptide	NN
cord-008530-yni0poh9	422	27	.	.	.
cord-008530-yni0poh9	423	1	Interestingly	interestingly	RB
cord-008530-yni0poh9	423	2	,	,	,
cord-008530-yni0poh9	423	3	gpl20induced	gpl20induce	VBN
cord-008530-yni0poh9	423	4	neuronal	neuronal	JJ
cord-008530-yni0poh9	423	5	apoptosis	apoptosis	NN
cord-008530-yni0poh9	423	6	in	in	IN
cord-008530-yni0poh9	423	7	this	this	DT
cord-008530-yni0poh9	423	8	model	model	NN
cord-008530-yni0poh9	423	9	system	system	NN
cord-008530-yni0poh9	423	10	was	be	VBD
cord-008530-yni0poh9	423	11	also	also	RB
cord-008530-yni0poh9	423	12	blocked	block	VBN
cord-008530-yni0poh9	423	13	by	by	IN
cord-008530-yni0poh9	423	14	the	the	DT
cord-008530-yni0poh9	423	15	CC	CC	NNP
cord-008530-yni0poh9	423	16	chemokines	chemokine	NNS
cord-008530-yni0poh9	423	17	RANTES	rante	NNS
cord-008530-yni0poh9	423	18	and	and	CC
cord-008530-yni0poh9	423	19	MIP	MIP	NNP
cord-008530-yni0poh9	423	20	-	-	HYPH
cord-008530-yni0poh9	423	21	I~	I~	NNP
cord-008530-yni0poh9	423	22	,	,	,
cord-008530-yni0poh9	423	23	which	which	WDT
cord-008530-yni0poh9	423	24	bind	bind	VBP
cord-008530-yni0poh9	423	25	to	to	IN
cord-008530-yni0poh9	423	26	CCR5	CCR5	NNP
cord-008530-yni0poh9	423	27	,	,	,
cord-008530-yni0poh9	423	28	suggesting	suggest	VBG
cord-008530-yni0poh9	423	29	there	there	EX
cord-008530-yni0poh9	423	30	may	may	MD
cord-008530-yni0poh9	423	31	be	be	VB
cord-008530-yni0poh9	423	32	regulatory	regulatory	JJ
cord-008530-yni0poh9	423	33	cross	cross	NN
cord-008530-yni0poh9	423	34	talk	talk	NN
cord-008530-yni0poh9	423	35	between	between	IN
cord-008530-yni0poh9	423	36	the	the	DT
cord-008530-yni0poh9	423	37	CCR5	CCR5	NNP
cord-008530-yni0poh9	423	38	and	and	CC
cord-008530-yni0poh9	423	39	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	423	40	receptors	receptor	NNS
cord-008530-yni0poh9	423	41	.	.	.
cord-008530-yni0poh9	424	1	However	however	RB
cord-008530-yni0poh9	424	2	,	,	,
cord-008530-yni0poh9	424	3	the	the	DT
cord-008530-yni0poh9	424	4	conclusion	conclusion	NN
cord-008530-yni0poh9	424	5	from	from	IN
cord-008530-yni0poh9	424	6	this	this	DT
cord-008530-yni0poh9	424	7	study	study	NN
cord-008530-yni0poh9	424	8	is	be	VBZ
cord-008530-yni0poh9	424	9	that	that	IN
cord-008530-yni0poh9	424	10	gpl20-induced	gpl20-induced	JJ
cord-008530-yni0poh9	424	11	neuronal	neuronal	JJ
cord-008530-yni0poh9	424	12	apoptosis	apoptosis	NN
cord-008530-yni0poh9	424	13	depends	depend	VBZ
cord-008530-yni0poh9	424	14	predominantly	predominantly	RB
cord-008530-yni0poh9	424	15	on	on	IN
cord-008530-yni0poh9	424	16	an	an	DT
cord-008530-yni0poh9	424	17	indirect	indirect	JJ
cord-008530-yni0poh9	424	18	pathway	pathway	NN
cord-008530-yni0poh9	424	19	via	via	IN
cord-008530-yni0poh9	424	20	activation	activation	NN
cord-008530-yni0poh9	424	21	of	of	IN
cord-008530-yni0poh9	424	22	chemokine	chemokine	NN
cord-008530-yni0poh9	424	23	receptors	receptor	NNS
cord-008530-yni0poh9	424	24	on	on	IN
cord-008530-yni0poh9	424	25	macrophages	macrophage	NNS
cord-008530-yni0poh9	424	26	microglia	microglia	NNS
cord-008530-yni0poh9	424	27	.	.	.
cord-008530-yni0poh9	425	1	Many	many	JJ
cord-008530-yni0poh9	425	2	possible	possible	JJ
cord-008530-yni0poh9	425	3	explanations	explanation	NNS
cord-008530-yni0poh9	425	4	exist	exist	VBP
cord-008530-yni0poh9	425	5	as	as	IN
cord-008530-yni0poh9	425	6	to	to	IN
cord-008530-yni0poh9	425	7	why	why	WRB
cord-008530-yni0poh9	425	8	there	there	EX
cord-008530-yni0poh9	425	9	are	be	VBP
cord-008530-yni0poh9	425	10	differences	difference	NNS
cord-008530-yni0poh9	425	11	between	between	IN
cord-008530-yni0poh9	425	12	these	these	DT
cord-008530-yni0poh9	425	13	studies	study	NNS
cord-008530-yni0poh9	425	14	with	with	IN
cord-008530-yni0poh9	425	15	respect	respect	NN
cord-008530-yni0poh9	425	16	to	to	IN
cord-008530-yni0poh9	425	17	the	the	DT
cord-008530-yni0poh9	425	18	observed	observed	JJ
cord-008530-yni0poh9	425	19	effects	effect	NNS
cord-008530-yni0poh9	425	20	of	of	IN
cord-008530-yni0poh9	425	21	gpl20	gpl20	NNP
cord-008530-yni0poh9	425	22	's	's	POS
cord-008530-yni0poh9	425	23	being	be	VBG
cord-008530-yni0poh9	425	24	conveyed	convey	VBN
cord-008530-yni0poh9	425	25	by	by	IN
cord-008530-yni0poh9	425	26	direct	direct	JJ
cord-008530-yni0poh9	425	27	or	or	CC
cord-008530-yni0poh9	425	28	indirect	indirect	JJ
cord-008530-yni0poh9	425	29	pathways	pathway	NNS
cord-008530-yni0poh9	425	30	.	.	.
cord-008530-yni0poh9	426	1	These	these	DT
cord-008530-yni0poh9	426	2	include	include	VBP
cord-008530-yni0poh9	426	3	differences	difference	NNS
cord-008530-yni0poh9	426	4	in	in	IN
cord-008530-yni0poh9	426	5	the	the	DT
cord-008530-yni0poh9	426	6	species	specie	NNS
cord-008530-yni0poh9	426	7	and	and	CC
cord-008530-yni0poh9	426	8	types	type	NNS
cord-008530-yni0poh9	426	9	of	of	IN
cord-008530-yni0poh9	426	10	neuronal	neuronal	JJ
cord-008530-yni0poh9	426	11	or	or	CC
cord-008530-yni0poh9	426	12	brain	brain	NN
cord-008530-yni0poh9	426	13	-	-	HYPH
cord-008530-yni0poh9	426	14	cell	cell	NN
cord-008530-yni0poh9	426	15	cultures	culture	NNS
cord-008530-yni0poh9	426	16	used	use	VBN
cord-008530-yni0poh9	426	17	and	and	CC
cord-008530-yni0poh9	426	18	the	the	DT
cord-008530-yni0poh9	426	19	types	type	NNS
cord-008530-yni0poh9	426	20	,	,	,
cord-008530-yni0poh9	426	21	form	form	NN
cord-008530-yni0poh9	426	22	,	,	,
cord-008530-yni0poh9	426	23	and	and	CC
cord-008530-yni0poh9	426	24	levels	level	NNS
cord-008530-yni0poh9	426	25	ofgpl20	ofgpl20	NNP
cord-008530-yni0poh9	426	26	added	add	VBD
cord-008530-yni0poh9	426	27	to	to	IN
cord-008530-yni0poh9	426	28	the	the	DT
cord-008530-yni0poh9	426	29	cultures	culture	NNS
cord-008530-yni0poh9	426	30	.	.	.
cord-008530-yni0poh9	427	1	While	while	IN
cord-008530-yni0poh9	427	2	the	the	DT
cord-008530-yni0poh9	427	3	question	question	NN
cord-008530-yni0poh9	427	4	of	of	IN
cord-008530-yni0poh9	427	5	whether	whether	IN
cord-008530-yni0poh9	427	6	the	the	DT
cord-008530-yni0poh9	427	7	induction	induction	NN
cord-008530-yni0poh9	427	8	of	of	IN
cord-008530-yni0poh9	427	9	neuronal	neuronal	JJ
cord-008530-yni0poh9	427	10	apoptosis	apoptosis	NN
cord-008530-yni0poh9	427	11	by	by	IN
cord-008530-yni0poh9	427	12	gpl20	gpl20	NNP
cord-008530-yni0poh9	427	13	is	be	VBZ
cord-008530-yni0poh9	427	14	consequent	consequent	JJ
cord-008530-yni0poh9	427	15	to	to	IN
cord-008530-yni0poh9	427	16	interaction	interaction	NN
cord-008530-yni0poh9	427	17	directly	directly	RB
cord-008530-yni0poh9	427	18	with	with	IN
cord-008530-yni0poh9	427	19	the	the	DT
cord-008530-yni0poh9	427	20	CXCR4	cxcr4	NN
cord-008530-yni0poh9	427	21	receptor	receptor	NN
cord-008530-yni0poh9	427	22	on	on	IN
cord-008530-yni0poh9	427	23	neurons	neuron	NNS
cord-008530-yni0poh9	427	24	or	or	CC
cord-008530-yni0poh9	427	25	occurs	occur	VBZ
cord-008530-yni0poh9	427	26	indirectly	indirectly	RB
cord-008530-yni0poh9	427	27	,	,	,
cord-008530-yni0poh9	427	28	following	follow	VBG
cord-008530-yni0poh9	427	29	activation	activation	NN
cord-008530-yni0poh9	427	30	of	of	IN
cord-008530-yni0poh9	427	31	the	the	DT
cord-008530-yni0poh9	427	32	macrophage	macrophage	NN
cord-008530-yni0poh9	427	33	/	/	SYM
cord-008530-yni0poh9	427	34	microglia	microglia	NNS
cord-008530-yni0poh9	427	35	,	,	,
cord-008530-yni0poh9	427	36	is	be	VBZ
cord-008530-yni0poh9	427	37	unresolved	unresolved	JJ
cord-008530-yni0poh9	427	38	,	,	,
cord-008530-yni0poh9	427	39	there	there	EX
cord-008530-yni0poh9	427	40	is	be	VBZ
cord-008530-yni0poh9	427	41	general	general	JJ
cord-008530-yni0poh9	427	42	agreement	agreement	NN
cord-008530-yni0poh9	427	43	that	that	WDT
cord-008530-yni0poh9	427	44	HIVgpl20	HIVgpl20	NNP
cord-008530-yni0poh9	427	45	binding	bind	VBG
cord-008530-yni0poh9	427	46	to	to	IN
cord-008530-yni0poh9	427	47	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	427	48	can	can	MD
cord-008530-yni0poh9	427	49	regulate	regulate	VB
cord-008530-yni0poh9	427	50	a	a	DT
cord-008530-yni0poh9	427	51	number	number	NN
cord-008530-yni0poh9	427	52	of	of	IN
cord-008530-yni0poh9	427	53	cellular	cellular	JJ
cord-008530-yni0poh9	427	54	signaling	signal	VBG
cord-008530-yni0poh9	427	55	pathways	pathway	NNS
cord-008530-yni0poh9	427	56	(	(	-LRB-
cord-008530-yni0poh9	427	57	Kaul	Kaul	NNP
cord-008530-yni0poh9	427	58	and	and	CC
cord-008530-yni0poh9	427	59	Lipton	Lipton	NNP
cord-008530-yni0poh9	427	60	,	,	,
cord-008530-yni0poh9	427	61	1999	1999	CD
cord-008530-yni0poh9	427	62	;	;	:
cord-008530-yni0poh9	427	63	Meucci	Meucci	NNP
cord-008530-yni0poh9	427	64	et	et	NNP
cord-008530-yni0poh9	427	65	al	al	NNP
cord-008530-yni0poh9	427	66	.	.	NNP
cord-008530-yni0poh9	427	67	,	,	,
cord-008530-yni0poh9	427	68	1998	1998	CD
cord-008530-yni0poh9	427	69	;	;	:
cord-008530-yni0poh9	428	1	Zheng	Zheng	NNP
cord-008530-yni0poh9	428	2	et	et	NNP
cord-008530-yni0poh9	428	3	al	al	NNP
cord-008530-yni0poh9	428	4	.	.	.
cord-008530-yni0poh9	429	1	,	,	,
cord-008530-yni0poh9	429	2	1999a	1999a	CD
cord-008530-yni0poh9	429	3	;	;	:
cord-008530-yni0poh9	429	4	Zheng	Zheng	NNP
cord-008530-yni0poh9	429	5	et	et	NNP
cord-008530-yni0poh9	429	6	al	al	NNP
cord-008530-yni0poh9	429	7	.	.	.
cord-008530-yni0poh9	430	1	,	,	,
cord-008530-yni0poh9	430	2	1999b	1999b	CD
cord-008530-yni0poh9	430	3	)	)	-RRB-
cord-008530-yni0poh9	430	4	.	.	.
cord-008530-yni0poh9	431	1	These	these	DT
cord-008530-yni0poh9	431	2	include	include	VBP
cord-008530-yni0poh9	431	3	inhibition	inhibition	NN
cord-008530-yni0poh9	431	4	of	of	IN
cord-008530-yni0poh9	431	5	cyclic	cyclic	JJ
cord-008530-yni0poh9	431	6	AMP	amp	NN
cord-008530-yni0poh9	431	7	;	;	:
cord-008530-yni0poh9	431	8	activation	activation	NN
cord-008530-yni0poh9	431	9	of	of	IN
cord-008530-yni0poh9	431	10	phosphoinositol	phosphoinositol	NNP
cord-008530-yni0poh9	431	11	(	(	-LRB-
cord-008530-yni0poh9	431	12	PI	pi	NN
cord-008530-yni0poh9	431	13	)	)	-RRB-
cord-008530-yni0poh9	431	14	hydrolysis	hydrolysis	NN
cord-008530-yni0poh9	431	15	,	,	,
cord-008530-yni0poh9	431	16	which	which	WDT
cord-008530-yni0poh9	431	17	is	be	VBZ
cord-008530-yni0poh9	431	18	partially	partially	RB
cord-008530-yni0poh9	431	19	prevented	prevent	VBN
cord-008530-yni0poh9	431	20	by	by	IN
cord-008530-yni0poh9	431	21	antibody	antibody	NN
cord-008530-yni0poh9	431	22	to	to	IN
cord-008530-yni0poh9	431	23	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	432	1	(	(	-LRB-
cord-008530-yni0poh9	432	2	Zheng	Zheng	NNP
cord-008530-yni0poh9	432	3	et	et	NNP
cord-008530-yni0poh9	432	4	al	al	NNP
cord-008530-yni0poh9	432	5	.	.	.
cord-008530-yni0poh9	433	1	,	,	,
cord-008530-yni0poh9	433	2	1999a	1999a	CD
cord-008530-yni0poh9	433	3	;	;	:
cord-008530-yni0poh9	433	4	Zheng	Zheng	NNP
cord-008530-yni0poh9	433	5	et	et	NNP
cord-008530-yni0poh9	433	6	al	al	NNP
cord-008530-yni0poh9	433	7	.	.	NNP
cord-008530-yni0poh9	433	8	,	,	,
cord-008530-yni0poh9	433	9	1999b	1999b	CD
cord-008530-yni0poh9	433	10	)	)	-RRB-
cord-008530-yni0poh9	433	11	;	;	:
cord-008530-yni0poh9	433	12	activation	activation	NN
cord-008530-yni0poh9	433	13	of	of	IN
cord-008530-yni0poh9	433	14	p38	p38	CD
cord-008530-yni0poh9	433	15	mitogen	mitogen	NNP
cord-008530-yni0poh9	433	16	-	-	HYPH
cord-008530-yni0poh9	433	17	activated	activate	VBN
cord-008530-yni0poh9	433	18	kinase	kinase	NN
cord-008530-yni0poh9	433	19	(	(	-LRB-
cord-008530-yni0poh9	433	20	p38	p38	CD
cord-008530-yni0poh9	433	21	MAPK	MAPK	NNP
cord-008530-yni0poh9	433	22	)	)	-RRB-
cord-008530-yni0poh9	434	1	(	(	-LRB-
cord-008530-yni0poh9	434	2	Kaul	Kaul	NNP
cord-008530-yni0poh9	434	3	and	and	CC
cord-008530-yni0poh9	434	4	Lipton	Lipton	NNP
cord-008530-yni0poh9	434	5	,	,	,
cord-008530-yni0poh9	434	6	1999	1999	CD
cord-008530-yni0poh9	434	7	)	)	-RRB-
cord-008530-yni0poh9	434	8	;	;	:
cord-008530-yni0poh9	434	9	and	and	CC
cord-008530-yni0poh9	434	10	increased	increase	VBD
cord-008530-yni0poh9	434	11	Ca	Ca	NNP
cord-008530-yni0poh9	434	12	2	2	CD
cord-008530-yni0poh9	434	13	+	+	CC
cord-008530-yni0poh9	434	14	mobilization	mobilization	NN
cord-008530-yni0poh9	434	15	(	(	-LRB-
cord-008530-yni0poh9	434	16	Meucci	Meucci	NNP
cord-008530-yni0poh9	434	17	et	et	NNP
cord-008530-yni0poh9	434	18	al	al	NNP
cord-008530-yni0poh9	434	19	.	.	NNP
cord-008530-yni0poh9	434	20	,	,	,
cord-008530-yni0poh9	434	21	1998	1998	CD
cord-008530-yni0poh9	434	22	)	)	-RRB-
cord-008530-yni0poh9	434	23	.	.	.
cord-008530-yni0poh9	435	1	HIV	HIV	NNP
cord-008530-yni0poh9	435	2	gpl20	gpl20	NNP
cord-008530-yni0poh9	436	1	neuronal	neuronal	JJ
cord-008530-yni0poh9	436	2	apoptosis	apoptosis	NN
cord-008530-yni0poh9	436	3	can	can	MD
cord-008530-yni0poh9	436	4	be	be	VB
cord-008530-yni0poh9	436	5	inhibited	inhibit	VBN
cord-008530-yni0poh9	436	6	by	by	IN
cord-008530-yni0poh9	436	7	inhibitors	inhibitor	NNS
cord-008530-yni0poh9	436	8	of	of	IN
cord-008530-yni0poh9	436	9	p38	p38	CD
cord-008530-yni0poh9	436	10	MAPK	MAPK	NNP
cord-008530-yni0poh9	436	11	(	(	-LRB-
cord-008530-yni0poh9	436	12	Kaul	Kaul	NNP
cord-008530-yni0poh9	436	13	and	and	CC
cord-008530-yni0poh9	436	14	Lipton	Lipton	NNP
cord-008530-yni0poh9	436	15	,	,	,
cord-008530-yni0poh9	436	16	1999	1999	CD
cord-008530-yni0poh9	436	17	)	)	-RRB-
cord-008530-yni0poh9	436	18	and	and	CC
cord-008530-yni0poh9	436	19	by	by	IN
cord-008530-yni0poh9	436	20	calcium	calcium	NN
cord-008530-yni0poh9	436	21	/	/	SYM
cord-008530-yni0poh9	436	22	calmodulin	calmodulin	NN
cord-008530-yni0poh9	436	23	-	-	HYPH
cord-008530-yni0poh9	436	24	dependent	dependent	JJ
cord-008530-yni0poh9	436	25	protein	protein	NN
cord-008530-yni0poh9	436	26	kinase	kinase	NN
cord-008530-yni0poh9	436	27	II	II	NNP
cord-008530-yni0poh9	436	28	,	,	,
cord-008530-yni0poh9	436	29	protein	protein	NN
cord-008530-yni0poh9	436	30	kinase	kinase	VBZ
cord-008530-yni0poh9	436	31	A	A	NNP
cord-008530-yni0poh9	436	32	,	,	,
cord-008530-yni0poh9	436	33	and	and	CC
cord-008530-yni0poh9	436	34	protein	protein	NN
cord-008530-yni0poh9	436	35	kinase	kinase	NN
cord-008530-yni0poh9	436	36	C	C	NNP
cord-008530-yni0poh9	437	1	(	(	-LRB-
cord-008530-yni0poh9	437	2	Zheng	Zheng	NNP
cord-008530-yni0poh9	437	3	et	et	NNP
cord-008530-yni0poh9	437	4	al	al	NNP
cord-008530-yni0poh9	437	5	.	.	NNP
cord-008530-yni0poh9	437	6	,	,	,
cord-008530-yni0poh9	437	7	1999a	1999a	CD
cord-008530-yni0poh9	437	8	)	)	-RRB-
cord-008530-yni0poh9	437	9	,	,	,
cord-008530-yni0poh9	437	10	linking	link	VBG
cord-008530-yni0poh9	437	11	neuronal	neuronal	JJ
cord-008530-yni0poh9	437	12	apoptosis	apoptosis	NN
cord-008530-yni0poh9	437	13	,	,	,
cord-008530-yni0poh9	437	14	in	in	IN
cord-008530-yni0poh9	437	15	part	part	NN
cord-008530-yni0poh9	437	16	,	,	,
cord-008530-yni0poh9	437	17	to	to	IN
cord-008530-yni0poh9	437	18	these	these	DT
cord-008530-yni0poh9	437	19	signal	signal	NN
cord-008530-yni0poh9	437	20	transduction	transduction	NN
cord-008530-yni0poh9	437	21	pathways	pathway	NNS
cord-008530-yni0poh9	437	22	.	.	.
cord-008530-yni0poh9	438	1	The	the	DT
cord-008530-yni0poh9	438	2	preceding	precede	VBG
cord-008530-yni0poh9	438	3	discussion	discussion	NN
cord-008530-yni0poh9	438	4	indicates	indicate	VBZ
cord-008530-yni0poh9	438	5	that	that	IN
cord-008530-yni0poh9	438	6	HIV	HIV	NNP
cord-008530-yni0poh9	438	7	gpl20	gpl20	NNP
cord-008530-yni0poh9	438	8	neurotoxicity	neurotoxicity	NN
cord-008530-yni0poh9	438	9	likely	likely	RB
cord-008530-yni0poh9	438	10	involves	involve	VBZ
cord-008530-yni0poh9	438	11	,	,	,
cord-008530-yni0poh9	438	12	in	in	IN
cord-008530-yni0poh9	438	13	part	part	NN
cord-008530-yni0poh9	438	14	,	,	,
cord-008530-yni0poh9	438	15	the	the	DT
cord-008530-yni0poh9	438	16	chemokine	chemokine	NN
cord-008530-yni0poh9	438	17	receptor	receptor	NN
cord-008530-yni0poh9	438	18	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	438	19	,	,	,
cord-008530-yni0poh9	438	20	raising	raise	VBG
cord-008530-yni0poh9	438	21	the	the	DT
cord-008530-yni0poh9	438	22	possibility	possibility	NN
cord-008530-yni0poh9	438	23	that	that	IN
cord-008530-yni0poh9	438	24	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	438	25	subverts	subvert	VBZ
cord-008530-yni0poh9	438	26	a	a	DT
cord-008530-yni0poh9	438	27	key	key	JJ
cord-008530-yni0poh9	438	28	physiological	physiological	JJ
cord-008530-yni0poh9	438	29	cell	cell	NN
cord-008530-yni0poh9	438	30	death	death	NN
cord-008530-yni0poh9	438	31	pathway	pathway	NN
cord-008530-yni0poh9	438	32	.	.	.
cord-008530-yni0poh9	439	1	As	as	IN
cord-008530-yni0poh9	439	2	we	-PRON-	PRP
cord-008530-yni0poh9	439	3	noted	note	VBD
cord-008530-yni0poh9	439	4	above	above	RB
cord-008530-yni0poh9	439	5	,	,	,
cord-008530-yni0poh9	439	6	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	439	7	/	/	SYM
cord-008530-yni0poh9	439	8	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	439	9	signaling	signaling	NN
cord-008530-yni0poh9	439	10	is	be	VBZ
cord-008530-yni0poh9	439	11	crucial	crucial	JJ
cord-008530-yni0poh9	439	12	for	for	IN
cord-008530-yni0poh9	439	13	normal	normal	JJ
cord-008530-yni0poh9	439	14	cerebellar	cerebellar	JJ
cord-008530-yni0poh9	439	15	neuronal	neuronal	JJ
cord-008530-yni0poh9	439	16	migration	migration	NN
cord-008530-yni0poh9	439	17	and	and	CC
cord-008530-yni0poh9	439	18	patterning	patterning	NN
cord-008530-yni0poh9	439	19	during	during	IN
cord-008530-yni0poh9	439	20	CNS	CNS	NNP
cord-008530-yni0poh9	439	21	development	development	NN
cord-008530-yni0poh9	439	22	.	.	.
cord-008530-yni0poh9	440	1	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	440	2	is	be	VBZ
cord-008530-yni0poh9	440	3	expressed	express	VBN
cord-008530-yni0poh9	440	4	constitutively	constitutively	RB
cord-008530-yni0poh9	440	5	in	in	IN
cord-008530-yni0poh9	440	6	the	the	DT
cord-008530-yni0poh9	440	7	adult	adult	NN
cord-008530-yni0poh9	440	8	CNS	CNS	NNP
cord-008530-yni0poh9	440	9	predominantly	predominantly	RB
cord-008530-yni0poh9	440	10	by	by	IN
cord-008530-yni0poh9	440	11	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	440	12	and	and	CC
cord-008530-yni0poh9	440	13	to	to	IN
cord-008530-yni0poh9	440	14	a	a	DT
cord-008530-yni0poh9	440	15	lesser	less	JJR
cord-008530-yni0poh9	440	16	degree	degree	NN
cord-008530-yni0poh9	440	17	by	by	IN
cord-008530-yni0poh9	440	18	neurons	neuron	NNS
cord-008530-yni0poh9	440	19	,	,	,
cord-008530-yni0poh9	440	20	raising	raise	VBG
cord-008530-yni0poh9	440	21	the	the	DT
cord-008530-yni0poh9	440	22	likelihood	likelihood	NN
cord-008530-yni0poh9	440	23	that	that	IN
cord-008530-yni0poh9	440	24	this	this	DT
cord-008530-yni0poh9	440	25	chemokine	chemokine	NN
cord-008530-yni0poh9	440	26	may	may	MD
cord-008530-yni0poh9	440	27	regulate	regulate	VB
cord-008530-yni0poh9	440	28	physiological	physiological	JJ
cord-008530-yni0poh9	440	29	processes	process	NNS
cord-008530-yni0poh9	440	30	in	in	IN
cord-008530-yni0poh9	440	31	the	the	DT
cord-008530-yni0poh9	440	32	adult	adult	NN
cord-008530-yni0poh9	440	33	brain	brain	NN
cord-008530-yni0poh9	440	34	.	.	.
cord-008530-yni0poh9	441	1	In	in	IN
cord-008530-yni0poh9	441	2	support	support	NN
cord-008530-yni0poh9	441	3	of	of	IN
cord-008530-yni0poh9	441	4	this	this	DT
cord-008530-yni0poh9	441	5	,	,	,
cord-008530-yni0poh9	441	6	SDF	SDF	NNP
cord-008530-yni0poh9	441	7	-	-	HYPH
cord-008530-yni0poh9	441	8	la	la	NNP
cord-008530-yni0poh9	441	9	regulates	regulate	VBZ
cord-008530-yni0poh9	441	10	a	a	DT
cord-008530-yni0poh9	441	11	number	number	NN
cord-008530-yni0poh9	441	12	of	of	IN
cord-008530-yni0poh9	441	13	signal	signal	NN
cord-008530-yni0poh9	441	14	transduction	transduction	NN
cord-008530-yni0poh9	441	15	pathways	pathway	NNS
cord-008530-yni0poh9	441	16	in	in	IN
cord-008530-yni0poh9	441	17	neurons	neuron	NNS
cord-008530-yni0poh9	441	18	,	,	,
cord-008530-yni0poh9	441	19	causing	cause	VBG
cord-008530-yni0poh9	441	20	decreased	decrease	VBN
cord-008530-yni0poh9	441	21	cyclic	cyclic	JJ
cord-008530-yni0poh9	441	22	AMP	amp	NN
cord-008530-yni0poh9	441	23	,	,	,
cord-008530-yni0poh9	441	24	increased	increase	VBN
cord-008530-yni0poh9	441	25	PI	pi	NN
cord-008530-yni0poh9	441	26	hydrolysis	hydrolysis	NN
cord-008530-yni0poh9	441	27	,	,	,
cord-008530-yni0poh9	441	28	activation	activation	NN
cord-008530-yni0poh9	441	29	of	of	IN
cord-008530-yni0poh9	441	30	p38MAPK	p38MAPK	NNPS
cord-008530-yni0poh9	441	31	,	,	,
cord-008530-yni0poh9	441	32	and	and	CC
cord-008530-yni0poh9	441	33	increased	increase	VBD
cord-008530-yni0poh9	441	34	Ca	Ca	NNP
cord-008530-yni0poh9	441	35	2	2	CD
cord-008530-yni0poh9	441	36	+	+	CC
cord-008530-yni0poh9	441	37	mobilization	mobilization	NN
cord-008530-yni0poh9	441	38	(	(	-LRB-
cord-008530-yni0poh9	441	39	Kaul	Kaul	NNP
cord-008530-yni0poh9	441	40	and	and	CC
cord-008530-yni0poh9	441	41	Lipton	Lipton	NNP
cord-008530-yni0poh9	441	42	,	,	,
cord-008530-yni0poh9	441	43	1999	1999	CD
cord-008530-yni0poh9	441	44	;	;	:
cord-008530-yni0poh9	441	45	Meucci	Meucci	NNP
cord-008530-yni0poh9	441	46	et	et	NNP
cord-008530-yni0poh9	441	47	al	al	NNP
cord-008530-yni0poh9	441	48	.	.	NNP
cord-008530-yni0poh9	441	49	,	,	,
cord-008530-yni0poh9	441	50	1998	1998	CD
cord-008530-yni0poh9	441	51	;	;	:
cord-008530-yni0poh9	441	52	Zheng	Zheng	NNP
cord-008530-yni0poh9	441	53	et	et	NNP
cord-008530-yni0poh9	441	54	al	al	NNP
cord-008530-yni0poh9	441	55	.	.	NNP
cord-008530-yni0poh9	441	56	,	,	,
cord-008530-yni0poh9	441	57	1999a	1999a	CD
cord-008530-yni0poh9	441	58	)	)	-RRB-
cord-008530-yni0poh9	441	59	.	.	.
cord-008530-yni0poh9	442	1	Functionally	functionally	RB
cord-008530-yni0poh9	442	2	,	,	,
cord-008530-yni0poh9	442	3	exposure	exposure	NN
cord-008530-yni0poh9	442	4	of	of	IN
cord-008530-yni0poh9	442	5	hippocampal	hippocampal	JJ
cord-008530-yni0poh9	442	6	neurons	neuron	NNS
cord-008530-yni0poh9	442	7	to	to	IN
cord-008530-yni0poh9	442	8	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	442	9	results	result	NNS
cord-008530-yni0poh9	442	10	in	in	IN
cord-008530-yni0poh9	442	11	increased	increase	VBN
cord-008530-yni0poh9	442	12	synaptic	synaptic	JJ
cord-008530-yni0poh9	442	13	transmission	transmission	NN
cord-008530-yni0poh9	442	14	,	,	,
cord-008530-yni0poh9	442	15	which	which	WDT
cord-008530-yni0poh9	442	16	is	be	VBZ
cord-008530-yni0poh9	442	17	blocked	block	VBN
cord-008530-yni0poh9	442	18	by	by	IN
cord-008530-yni0poh9	442	19	antibodies	antibody	NNS
cord-008530-yni0poh9	442	20	to	to	IN
cord-008530-yni0poh9	442	21	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	443	1	(	(	-LRB-
cord-008530-yni0poh9	443	2	Zheng	Zheng	NNP
cord-008530-yni0poh9	443	3	et	et	NNP
cord-008530-yni0poh9	443	4	al	al	NNP
cord-008530-yni0poh9	443	5	.	.	NNP
cord-008530-yni0poh9	443	6	,	,	,
cord-008530-yni0poh9	443	7	1999a	1999a	CD
cord-008530-yni0poh9	443	8	)	)	-RRB-
cord-008530-yni0poh9	443	9	.	.	.
cord-008530-yni0poh9	444	1	The	the	DT
cord-008530-yni0poh9	444	2	similar	similar	JJ
cord-008530-yni0poh9	444	3	effects	effect	NNS
cord-008530-yni0poh9	444	4	of	of	IN
cord-008530-yni0poh9	444	5	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	444	6	and	and	CC
cord-008530-yni0poh9	444	7	HIV	HIV	NNP
cord-008530-yni0poh9	444	8	gpl20	gpl20	NNP
cord-008530-yni0poh9	444	9	in	in	IN
cord-008530-yni0poh9	444	10	regulating	regulate	VBG
cord-008530-yni0poh9	444	11	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	445	1	signaling	signal	VBG
cord-008530-yni0poh9	445	2	raise	raise	VBP
cord-008530-yni0poh9	445	3	the	the	DT
cord-008530-yni0poh9	445	4	question	question	NN
cord-008530-yni0poh9	445	5	as	as	IN
cord-008530-yni0poh9	445	6	to	to	IN
cord-008530-yni0poh9	445	7	whether	whether	IN
cord-008530-yni0poh9	445	8	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	445	9	might	may	MD
cord-008530-yni0poh9	445	10	also	also	RB
cord-008530-yni0poh9	445	11	induce	induce	VB
cord-008530-yni0poh9	445	12	neuronal	neuronal	JJ
cord-008530-yni0poh9	445	13	apoptosis	apoptosis	NN
cord-008530-yni0poh9	445	14	.	.	.
cord-008530-yni0poh9	446	1	Here	here	RB
cord-008530-yni0poh9	446	2	,	,	,
cord-008530-yni0poh9	446	3	the	the	DT
cord-008530-yni0poh9	446	4	findings	finding	NNS
cord-008530-yni0poh9	446	5	have	have	VBP
cord-008530-yni0poh9	446	6	been	be	VBN
cord-008530-yni0poh9	446	7	conflicting	conflict	VBG
cord-008530-yni0poh9	446	8	.	.	.
cord-008530-yni0poh9	447	1	Four	four	CD
cord-008530-yni0poh9	447	2	studies	study	NNS
cord-008530-yni0poh9	447	3	revealed	reveal	VBD
cord-008530-yni0poh9	447	4	that	that	IN
cord-008530-yni0poh9	447	5	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	447	6	promoted	promote	VBD
cord-008530-yni0poh9	447	7	increased	increase	VBN
cord-008530-yni0poh9	447	8	neuronal	neuronal	JJ
cord-008530-yni0poh9	447	9	apoptosis	apoptosis	NN
cord-008530-yni0poh9	447	10	(	(	-LRB-
cord-008530-yni0poh9	447	11	Hesselgesser	Hesselgesser	NNP
cord-008530-yni0poh9	447	12	et	et	FW
cord-008530-yni0poh9	447	13	al	al	NNP
cord-008530-yni0poh9	447	14	.	.	NNP
cord-008530-yni0poh9	447	15	,	,	,
cord-008530-yni0poh9	447	16	1998	1998	CD
cord-008530-yni0poh9	447	17	;	;	:
cord-008530-yni0poh9	447	18	Kaul	Kaul	NNP
cord-008530-yni0poh9	447	19	and	and	CC
cord-008530-yni0poh9	447	20	Lipton	Lipton	NNP
cord-008530-yni0poh9	447	21	,	,	,
cord-008530-yni0poh9	447	22	1999	1999	CD
cord-008530-yni0poh9	447	23	;	;	:
cord-008530-yni0poh9	447	24	Zheng	Zheng	NNP
cord-008530-yni0poh9	447	25	et	et	NNP
cord-008530-yni0poh9	447	26	al	al	NNP
cord-008530-yni0poh9	447	27	.	.	NNP
cord-008530-yni0poh9	447	28	,	,	,
cord-008530-yni0poh9	447	29	1999b	1999b	CD
cord-008530-yni0poh9	447	30	)	)	-RRB-
cord-008530-yni0poh9	447	31	and	and	CC
cord-008530-yni0poh9	447	32	activation	activation	NN
cord-008530-yni0poh9	447	33	of	of	IN
cord-008530-yni0poh9	447	34	a	a	DT
cord-008530-yni0poh9	447	35	key	key	JJ
cord-008530-yni0poh9	447	36	cell	cell	NN
cord-008530-yni0poh9	447	37	death	death	NN
cord-008530-yni0poh9	447	38	gene	gene	NN
cord-008530-yni0poh9	447	39	,	,	,
cord-008530-yni0poh9	447	40	caspase	caspase	NN
cord-008530-yni0poh9	447	41	3	3	CD
cord-008530-yni0poh9	448	1	(	(	-LRB-
cord-008530-yni0poh9	448	2	Zheng	Zheng	NNP
cord-008530-yni0poh9	448	3	et	et	NNP
cord-008530-yni0poh9	448	4	al	al	NNP
cord-008530-yni0poh9	448	5	.	.	NNP
cord-008530-yni0poh9	448	6	,	,	,
cord-008530-yni0poh9	448	7	1999a	1999a	CD
cord-008530-yni0poh9	448	8	)	)	-RRB-
cord-008530-yni0poh9	448	9	.	.	.
cord-008530-yni0poh9	449	1	In	in	IN
cord-008530-yni0poh9	449	2	contrast	contrast	NN
cord-008530-yni0poh9	449	3	to	to	IN
cord-008530-yni0poh9	449	4	these	these	DT
cord-008530-yni0poh9	449	5	findings	finding	NNS
cord-008530-yni0poh9	449	6	,	,	,
cord-008530-yni0poh9	449	7	Meucci	Meucci	NNP
cord-008530-yni0poh9	449	8	and	and	CC
cord-008530-yni0poh9	449	9	colleagues	colleague	NNS
cord-008530-yni0poh9	449	10	reported	report	VBD
cord-008530-yni0poh9	449	11	that	that	IN
cord-008530-yni0poh9	449	12	,	,	,
cord-008530-yni0poh9	449	13	following	follow	VBG
cord-008530-yni0poh9	449	14	treatment	treatment	NN
cord-008530-yni0poh9	449	15	with	with	IN
cord-008530-yni0poh9	449	16	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	449	17	,	,	,
cord-008530-yni0poh9	449	18	there	there	EX
cord-008530-yni0poh9	449	19	was	be	VBD
cord-008530-yni0poh9	449	20	marked	mark	VBN
cord-008530-yni0poh9	449	21	protection	protection	NN
cord-008530-yni0poh9	449	22	of	of	IN
cord-008530-yni0poh9	449	23	neurons	neuron	NNS
cord-008530-yni0poh9	449	24	from	from	IN
cord-008530-yni0poh9	449	25	culture	culture	NN
cord-008530-yni0poh9	449	26	-	-	:
cord-008530-yni0poh9	449	27	and	and	CC
cord-008530-yni0poh9	449	28	HIV	HIV	NNP
cord-008530-yni0poh9	449	29	gpl20-induced	gpl20-induced	NN
cord-008530-yni0poh9	449	30	apoptosis	apoptosis	NN
cord-008530-yni0poh9	449	31	(	(	-LRB-
cord-008530-yni0poh9	449	32	Meucci	Meucci	NNP
cord-008530-yni0poh9	449	33	et	et	NNP
cord-008530-yni0poh9	449	34	al	al	NNP
cord-008530-yni0poh9	449	35	.	.	NNP
cord-008530-yni0poh9	449	36	,	,	,
cord-008530-yni0poh9	449	37	1998	1998	CD
cord-008530-yni0poh9	449	38	)	)	-RRB-
cord-008530-yni0poh9	449	39	.	.	.
cord-008530-yni0poh9	450	1	The	the	DT
cord-008530-yni0poh9	450	2	reason	reason	NN
cord-008530-yni0poh9	450	3	for	for	IN
cord-008530-yni0poh9	450	4	these	these	DT
cord-008530-yni0poh9	450	5	discrepancies	discrepancy	NNS
cord-008530-yni0poh9	450	6	is	be	VBZ
cord-008530-yni0poh9	450	7	not	not	RB
cord-008530-yni0poh9	450	8	known	know	VBN
cord-008530-yni0poh9	450	9	but	but	CC
cord-008530-yni0poh9	450	10	again	again	RB
cord-008530-yni0poh9	450	11	likely	likely	RB
cord-008530-yni0poh9	450	12	reflect	reflect	VBP
cord-008530-yni0poh9	450	13	differences	difference	NNS
cord-008530-yni0poh9	450	14	in	in	IN
cord-008530-yni0poh9	450	15	cell	cell	NN
cord-008530-yni0poh9	450	16	preparations	preparation	NNS
cord-008530-yni0poh9	450	17	and	and	CC
cord-008530-yni0poh9	450	18	culture	culture	NN
cord-008530-yni0poh9	450	19	conditions	condition	NNS
cord-008530-yni0poh9	450	20	.	.	.
cord-008530-yni0poh9	451	1	Similar	similar	JJ
cord-008530-yni0poh9	451	2	to	to	IN
cord-008530-yni0poh9	451	3	HIV	HIV	NNP
cord-008530-yni0poh9	451	4	,	,	,
cord-008530-yni0poh9	451	5	SIV	SIV	NNP
cord-008530-yni0poh9	451	6	infection	infection	NN
cord-008530-yni0poh9	451	7	of	of	IN
cord-008530-yni0poh9	451	8	macaques	macaque	NNS
cord-008530-yni0poh9	451	9	can	can	MD
cord-008530-yni0poh9	451	10	lead	lead	VB
cord-008530-yni0poh9	451	11	to	to	IN
cord-008530-yni0poh9	451	12	the	the	DT
cord-008530-yni0poh9	451	13	development	development	NN
cord-008530-yni0poh9	451	14	of	of	IN
cord-008530-yni0poh9	451	15	an	an	DT
cord-008530-yni0poh9	451	16	AIDS	AIDS	NNP
cord-008530-yni0poh9	451	17	-	-	HYPH
cord-008530-yni0poh9	451	18	associated	associate	VBN
cord-008530-yni0poh9	451	19	encephalitis	encephalitis	RB
cord-008530-yni0poh9	451	20	that	that	WDT
cord-008530-yni0poh9	451	21	is	be	VBZ
cord-008530-yni0poh9	451	22	virtually	virtually	RB
cord-008530-yni0poh9	451	23	indistinguishable	indistinguishable	JJ
cord-008530-yni0poh9	451	24	from	from	IN
cord-008530-yni0poh9	451	25	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	452	1	(	(	-LRB-
cord-008530-yni0poh9	452	2	Raghavan	Raghavan	NNP
cord-008530-yni0poh9	452	3	et	et	NNP
cord-008530-yni0poh9	452	4	al	al	NNP
cord-008530-yni0poh9	452	5	.	.	.
cord-008530-yni0poh9	453	1	,	,	,
cord-008530-yni0poh9	453	2	1999	1999	CD
cord-008530-yni0poh9	453	3	;	;	:
cord-008530-yni0poh9	453	4	Sasseville	Sasseville	NNP
cord-008530-yni0poh9	453	5	and	and	CC
cord-008530-yni0poh9	453	6	Lackner	Lackner	NNP
cord-008530-yni0poh9	453	7	,	,	,
cord-008530-yni0poh9	453	8	1997	1997	CD
cord-008530-yni0poh9	453	9	)	)	-RRB-
cord-008530-yni0poh9	453	10	.	.	.
cord-008530-yni0poh9	454	1	Both	both	DT
cord-008530-yni0poh9	454	2	T	T	NNP
cord-008530-yni0poh9	454	3	-	-	HYPH
cord-008530-yni0poh9	454	4	tropic	tropic	NNP
cord-008530-yni0poh9	454	5	and	and	CC
cord-008530-yni0poh9	454	6	M	M	NNP
cord-008530-yni0poh9	454	7	-	-	HYPH
cord-008530-yni0poh9	454	8	tropic	tropic	NNP
cord-008530-yni0poh9	455	1	SIV	SIV	NNP
cord-008530-yni0poh9	455	2	variants	variant	NNS
cord-008530-yni0poh9	455	3	have	have	VBP
cord-008530-yni0poh9	455	4	been	be	VBN
cord-008530-yni0poh9	455	5	isolated	isolate	VBN
cord-008530-yni0poh9	455	6	and	and	CC
cord-008530-yni0poh9	455	7	,	,	,
cord-008530-yni0poh9	455	8	like	like	IN
cord-008530-yni0poh9	455	9	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	455	10	,	,	,
cord-008530-yni0poh9	455	11	macrophage	macrophage	NN
cord-008530-yni0poh9	455	12	/	/	SYM
cord-008530-yni0poh9	455	13	microglia	microglia	NNS
cord-008530-yni0poh9	455	14	constitute	constitute	VBP
cord-008530-yni0poh9	455	15	the	the	DT
cord-008530-yni0poh9	455	16	primary	primary	JJ
cord-008530-yni0poh9	455	17	infected	infected	JJ
cord-008530-yni0poh9	455	18	target	target	NN
cord-008530-yni0poh9	455	19	cell	cell	NN
cord-008530-yni0poh9	455	20	population	population	NN
cord-008530-yni0poh9	455	21	in	in	IN
cord-008530-yni0poh9	455	22	the	the	DT
cord-008530-yni0poh9	455	23	brain	brain	NN
cord-008530-yni0poh9	455	24	of	of	IN
cord-008530-yni0poh9	455	25	SIV	SIV	NNP
cord-008530-yni0poh9	455	26	-	-	HYPH
cord-008530-yni0poh9	455	27	infected	infect	VBN
cord-008530-yni0poh9	455	28	monkeys	monkey	NNS
cord-008530-yni0poh9	455	29	.	.	.
cord-008530-yni0poh9	456	1	The	the	DT
cord-008530-yni0poh9	456	2	host	host	NN
cord-008530-yni0poh9	456	3	immune	immune	JJ
cord-008530-yni0poh9	456	4	system	system	NN
cord-008530-yni0poh9	456	5	plays	play	VBZ
cord-008530-yni0poh9	456	6	a	a	DT
cord-008530-yni0poh9	456	7	major	major	JJ
cord-008530-yni0poh9	456	8	role	role	NN
cord-008530-yni0poh9	456	9	in	in	IN
cord-008530-yni0poh9	456	10	the	the	DT
cord-008530-yni0poh9	456	11	infection	infection	NN
cord-008530-yni0poh9	456	12	of	of	IN
cord-008530-yni0poh9	456	13	the	the	DT
cord-008530-yni0poh9	456	14	CNS	CNS	NNP
cord-008530-yni0poh9	456	15	with	with	IN
cord-008530-yni0poh9	456	16	SIV	SIV	NNP
cord-008530-yni0poh9	456	17	,	,	,
cord-008530-yni0poh9	456	18	where	where	WRB
cord-008530-yni0poh9	456	19	perivascular	perivascular	JJ
cord-008530-yni0poh9	456	20	macrophages	macrophage	NNS
cord-008530-yni0poh9	456	21	are	be	VBP
cord-008530-yni0poh9	456	22	continuously	continuously	RB
cord-008530-yni0poh9	456	23	replaced	replace	VBN
cord-008530-yni0poh9	456	24	via	via	IN
cord-008530-yni0poh9	456	25	recruitment	recruitment	NN
cord-008530-yni0poh9	456	26	from	from	IN
cord-008530-yni0poh9	456	27	the	the	DT
cord-008530-yni0poh9	456	28	circulating	circulate	VBG
cord-008530-yni0poh9	456	29	monocyte	monocyte	NNP
cord-008530-yni0poh9	456	30	pool	pool	NN
cord-008530-yni0poh9	456	31	through	through	IN
cord-008530-yni0poh9	456	32	the	the	DT
cord-008530-yni0poh9	456	33	blood	blood	NN
cord-008530-yni0poh9	456	34	-	-	HYPH
cord-008530-yni0poh9	456	35	brain	brain	NN
cord-008530-yni0poh9	456	36	barrier	barrier	NN
cord-008530-yni0poh9	456	37	(	(	-LRB-
cord-008530-yni0poh9	456	38	Lane	Lane	NNP
cord-008530-yni0poh9	456	39	et	et	NNP
cord-008530-yni0poh9	456	40	al	al	NNP
cord-008530-yni0poh9	456	41	.	.	NNP
cord-008530-yni0poh9	456	42	,	,	,
cord-008530-yni0poh9	456	43	1996	1996	CD
cord-008530-yni0poh9	456	44	)	)	-RRB-
cord-008530-yni0poh9	456	45	.	.	.
cord-008530-yni0poh9	457	1	Thus	thus	RB
cord-008530-yni0poh9	457	2	,	,	,
cord-008530-yni0poh9	457	3	infected	infected	JJ
cord-008530-yni0poh9	457	4	T	t	NN
cord-008530-yni0poh9	457	5	cells	cell	NNS
cord-008530-yni0poh9	457	6	and	and	CC
cord-008530-yni0poh9	457	7	monocytes	monocyte	NNS
cord-008530-yni0poh9	457	8	likely	likely	RB
cord-008530-yni0poh9	457	9	enter	enter	VB
cord-008530-yni0poh9	457	10	the	the	DT
cord-008530-yni0poh9	457	11	CNS	CNS	NNP
cord-008530-yni0poh9	457	12	parenchyma	parenchyma	NNS
cord-008530-yni0poh9	457	13	during	during	IN
cord-008530-yni0poh9	457	14	the	the	DT
cord-008530-yni0poh9	457	15	asymptomatic	asymptomatic	JJ
cord-008530-yni0poh9	457	16	phase	phase	NN
cord-008530-yni0poh9	457	17	of	of	IN
cord-008530-yni0poh9	457	18	infection	infection	NN
cord-008530-yni0poh9	457	19	.	.	.
cord-008530-yni0poh9	458	1	In	in	IN
cord-008530-yni0poh9	458	2	addition	addition	NN
cord-008530-yni0poh9	458	3	to	to	IN
cord-008530-yni0poh9	458	4	leukocyte	leukocyte	NN
cord-008530-yni0poh9	458	5	and	and	CC
cord-008530-yni0poh9	458	6	endothelial	endothelial	JJ
cord-008530-yni0poh9	458	7	adhesion	adhesion	NN
cord-008530-yni0poh9	458	8	molecules	molecule	NNS
cord-008530-yni0poh9	458	9	,	,	,
cord-008530-yni0poh9	458	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	458	11	could	could	MD
cord-008530-yni0poh9	458	12	be	be	VB
cord-008530-yni0poh9	458	13	critical	critical	JJ
cord-008530-yni0poh9	458	14	components	component	NNS
cord-008530-yni0poh9	458	15	involved	involve	VBN
cord-008530-yni0poh9	458	16	in	in	IN
cord-008530-yni0poh9	458	17	SIV	SIV	NNP
cord-008530-yni0poh9	458	18	infection	infection	NN
cord-008530-yni0poh9	458	19	of	of	IN
cord-008530-yni0poh9	458	20	the	the	DT
cord-008530-yni0poh9	458	21	brain	brain	NN
cord-008530-yni0poh9	458	22	.	.	.
cord-008530-yni0poh9	459	1	Using	use	VBG
cord-008530-yni0poh9	459	2	immunohistochemical	immunohistochemical	JJ
cord-008530-yni0poh9	459	3	staining	stain	VBG
cord-008530-yni0poh9	459	4	to	to	TO
cord-008530-yni0poh9	459	5	investigate	investigate	VB
cord-008530-yni0poh9	459	6	chemokine	chemokine	JJ
cord-008530-yni0poh9	459	7	expression	expression	NN
cord-008530-yni0poh9	459	8	in	in	IN
cord-008530-yni0poh9	459	9	the	the	DT
cord-008530-yni0poh9	459	10	encephalitic	encephalitic	JJ
cord-008530-yni0poh9	459	11	brain	brain	NN
cord-008530-yni0poh9	459	12	of	of	IN
cord-008530-yni0poh9	459	13	SIV	SIV	NNP
cord-008530-yni0poh9	459	14	-	-	HYPH
cord-008530-yni0poh9	459	15	infected	infect	VBN
cord-008530-yni0poh9	459	16	macaques	macaque	NNS
cord-008530-yni0poh9	459	17	,	,	,
cord-008530-yni0poh9	459	18	Sasseville	Sasseville	NNP
cord-008530-yni0poh9	459	19	and	and	CC
cord-008530-yni0poh9	459	20	coworkers	coworker	NNS
cord-008530-yni0poh9	459	21	reported	report	VBD
cord-008530-yni0poh9	459	22	upregulation	upregulation	NN
cord-008530-yni0poh9	459	23	in	in	IN
cord-008530-yni0poh9	459	24	the	the	DT
cord-008530-yni0poh9	459	25	expression	expression	NN
cord-008530-yni0poh9	459	26	of	of	IN
cord-008530-yni0poh9	459	27	a	a	DT
cord-008530-yni0poh9	459	28	number	number	NN
cord-008530-yni0poh9	459	29	of	of	IN
cord-008530-yni0poh9	459	30	chemokines	chemokine	NNS
cord-008530-yni0poh9	459	31	,	,	,
cord-008530-yni0poh9	459	32	including	include	VBG
cord-008530-yni0poh9	459	33	MIP	MIP	NNP
cord-008530-yni0poh9	459	34	-	-	HYPH
cord-008530-yni0poh9	459	35	la	la	NNP
cord-008530-yni0poh9	459	36	,	,	,
cord-008530-yni0poh9	459	37	MIP	MIP	NNP
cord-008530-yni0poh9	459	38	-	-	HYPH
cord-008530-yni0poh9	459	39	I~	I~	NNP
cord-008530-yni0poh9	459	40	,	,	,
cord-008530-yni0poh9	459	41	RANTES	RANTES	NNP
cord-008530-yni0poh9	459	42	,	,	,
cord-008530-yni0poh9	459	43	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	459	44	,	,	,
cord-008530-yni0poh9	459	45	and	and	CC
cord-008530-yni0poh9	459	46	IP-10	IP-10	NNP
cord-008530-yni0poh9	459	47	,	,	,
cord-008530-yni0poh9	459	48	by	by	IN
cord-008530-yni0poh9	459	49	vascular	vascular	JJ
cord-008530-yni0poh9	459	50	endothelium	endothelium	NN
cord-008530-yni0poh9	459	51	and/or	and/or	CC
cord-008530-yni0poh9	459	52	perivascular	perivascular	JJ
cord-008530-yni0poh9	459	53	mononuclear	mononuclear	NN
cord-008530-yni0poh9	459	54	cells	cell	NNS
cord-008530-yni0poh9	459	55	.	.	.
cord-008530-yni0poh9	460	1	In	in	IN
cord-008530-yni0poh9	460	2	contrast	contrast	NN
cord-008530-yni0poh9	460	3	to	to	IN
cord-008530-yni0poh9	460	4	neuro	neuro	NNP
cord-008530-yni0poh9	460	5	AIDS	AIDS	NNP
cord-008530-yni0poh9	460	6	,	,	,
cord-008530-yni0poh9	460	7	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	460	8	was	be	VBD
cord-008530-yni0poh9	460	9	not	not	RB
cord-008530-yni0poh9	460	10	elevated	elevate	VBN
cord-008530-yni0poh9	460	11	in	in	IN
cord-008530-yni0poh9	460	12	the	the	DT
cord-008530-yni0poh9	460	13	SIV	SIV	NNP
cord-008530-yni0poh9	460	14	-	-	HYPH
cord-008530-yni0poh9	460	15	encephalitic	encephalitic	JJ
cord-008530-yni0poh9	460	16	monkey	monkey	NN
cord-008530-yni0poh9	460	17	brain	brain	NN
cord-008530-yni0poh9	460	18	.	.	.
cord-008530-yni0poh9	461	1	With	with	IN
cord-008530-yni0poh9	461	2	the	the	DT
cord-008530-yni0poh9	461	3	exception	exception	NN
cord-008530-yni0poh9	461	4	of	of	IN
cord-008530-yni0poh9	461	5	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	461	6	,	,	,
cord-008530-yni0poh9	461	7	expression	expression	NN
cord-008530-yni0poh9	461	8	of	of	IN
cord-008530-yni0poh9	461	9	these	these	DT
cord-008530-yni0poh9	461	10	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	461	11	chemokines	chemokine	NNS
cord-008530-yni0poh9	461	12	in	in	IN
cord-008530-yni0poh9	461	13	the	the	DT
cord-008530-yni0poh9	461	14	SIV	SIV	NNP
cord-008530-yni0poh9	461	15	-	-	HYPH
cord-008530-yni0poh9	461	16	infected	infect	VBN
cord-008530-yni0poh9	461	17	brain	brain	NN
cord-008530-yni0poh9	461	18	is	be	VBZ
cord-008530-yni0poh9	461	19	similar	similar	JJ
cord-008530-yni0poh9	461	20	to	to	IN
cord-008530-yni0poh9	461	21	that	that	DT
cord-008530-yni0poh9	461	22	found	find	VBN
cord-008530-yni0poh9	461	23	in	in	IN
cord-008530-yni0poh9	461	24	the	the	DT
cord-008530-yni0poh9	461	25	human	human	JJ
cord-008530-yni0poh9	461	26	brain	brain	NN
cord-008530-yni0poh9	461	27	in	in	IN
cord-008530-yni0poh9	461	28	neuroAIDS	neuroAIDS	NNP
cord-008530-yni0poh9	461	29	(	(	-LRB-
cord-008530-yni0poh9	461	30	as	as	IN
cord-008530-yni0poh9	461	31	noted	note	VBN
cord-008530-yni0poh9	461	32	above	above	RB
cord-008530-yni0poh9	461	33	)	)	-RRB-
cord-008530-yni0poh9	461	34	.	.	.
cord-008530-yni0poh9	462	1	However	however	RB
cord-008530-yni0poh9	462	2	,	,	,
cord-008530-yni0poh9	462	3	like	like	IN
cord-008530-yni0poh9	462	4	neu	neu	NNP
cord-008530-yni0poh9	462	5	-	-	HYPH
cord-008530-yni0poh9	462	6	roAIDS	roAIDS	NNP
cord-008530-yni0poh9	462	7	,	,	,
cord-008530-yni0poh9	462	8	the	the	DT
cord-008530-yni0poh9	462	9	in	in	IN
cord-008530-yni0poh9	462	10	vivo	vivo	NN
cord-008530-yni0poh9	462	11	function	function	NN
cord-008530-yni0poh9	462	12	of	of	IN
cord-008530-yni0poh9	462	13	these	these	DT
cord-008530-yni0poh9	462	14	chemokines	chemokine	NNS
cord-008530-yni0poh9	462	15	in	in	IN
cord-008530-yni0poh9	462	16	SIV	SIV	NNP
cord-008530-yni0poh9	462	17	-	-	HYPH
cord-008530-yni0poh9	462	18	encephalitis	encephalitis	RB
cord-008530-yni0poh9	462	19	remains	remain	VBZ
cord-008530-yni0poh9	462	20	unknown	unknown	JJ
cord-008530-yni0poh9	462	21	;	;	:
cord-008530-yni0poh9	462	22	it	-PRON-	PRP
cord-008530-yni0poh9	462	23	is	be	VBZ
cord-008530-yni0poh9	462	24	reasonable	reasonable	JJ
cord-008530-yni0poh9	462	25	speculation	speculation	NN
cord-008530-yni0poh9	462	26	however	however	RB
cord-008530-yni0poh9	462	27	,	,	,
cord-008530-yni0poh9	462	28	to	to	TO
cord-008530-yni0poh9	462	29	suggest	suggest	VB
cord-008530-yni0poh9	462	30	that	that	IN
cord-008530-yni0poh9	462	31	leukocyte	leukocyte	NN
cord-008530-yni0poh9	462	32	recruitment	recruitment	NN
cord-008530-yni0poh9	462	33	to	to	IN
cord-008530-yni0poh9	462	34	the	the	DT
cord-008530-yni0poh9	462	35	SIV	SIV	NNP
cord-008530-yni0poh9	462	36	-	-	HYPH
cord-008530-yni0poh9	462	37	infected	infect	VBN
cord-008530-yni0poh9	462	38	CNS	CNS	NNP
cord-008530-yni0poh9	462	39	may	may	MD
cord-008530-yni0poh9	462	40	be	be	VB
cord-008530-yni0poh9	462	41	directed	direct	VBN
cord-008530-yni0poh9	462	42	by	by	IN
cord-008530-yni0poh9	462	43	these	these	DT
cord-008530-yni0poh9	462	44	chemokines	chemokine	NNS
cord-008530-yni0poh9	462	45	.	.	.
cord-008530-yni0poh9	463	1	In	in	IN
cord-008530-yni0poh9	463	2	a	a	DT
cord-008530-yni0poh9	463	3	follow	follow	NN
cord-008530-yni0poh9	463	4	-	-	HYPH
cord-008530-yni0poh9	463	5	up	up	NN
cord-008530-yni0poh9	463	6	study	study	NN
cord-008530-yni0poh9	463	7	by	by	IN
cord-008530-yni0poh9	463	8	this	this	DT
cord-008530-yni0poh9	463	9	group	group	NN
cord-008530-yni0poh9	463	10	,	,	,
cord-008530-yni0poh9	463	11	examining	examine	VBG
cord-008530-yni0poh9	463	12	chemokine	chemokine	NN
cord-008530-yni0poh9	463	13	receptor	receptor	NN
cord-008530-yni0poh9	463	14	expression	expression	NN
cord-008530-yni0poh9	463	15	in	in	IN
cord-008530-yni0poh9	463	16	SIV	SIV	NNP
cord-008530-yni0poh9	463	17	-	-	HYPH
cord-008530-yni0poh9	463	18	AIDS	AIDS	NNP
cord-008530-yni0poh9	463	19	encephalitis	encephalitis	RB
cord-008530-yni0poh9	463	20	,	,	,
cord-008530-yni0poh9	463	21	the	the	DT
cord-008530-yni0poh9	463	22	chemokine	chemokine	NN
cord-008530-yni0poh9	463	23	receptors	receptor	NNS
cord-008530-yni0poh9	463	24	CCR3	CCR3	NNP
cord-008530-yni0poh9	463	25	,	,	,
cord-008530-yni0poh9	463	26	CCR5	CCR5	NNP
cord-008530-yni0poh9	463	27	,	,	,
cord-008530-yni0poh9	463	28	CXCR3	cxcr3	XX
cord-008530-yni0poh9	463	29	,	,	,
cord-008530-yni0poh9	463	30	and	and	CC
cord-008530-yni0poh9	463	31	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	463	32	were	be	VBD
cord-008530-yni0poh9	463	33	found	find	VBN
cord-008530-yni0poh9	463	34	to	to	TO
cord-008530-yni0poh9	463	35	be	be	VB
cord-008530-yni0poh9	463	36	expressed	express	VBN
cord-008530-yni0poh9	463	37	by	by	IN
cord-008530-yni0poh9	463	38	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	463	39	cells	cell	NNS
cord-008530-yni0poh9	463	40	within	within	IN
cord-008530-yni0poh9	463	41	perivascular	perivascular	JJ
cord-008530-yni0poh9	463	42	lesions	lesion	NNS
cord-008530-yni0poh9	463	43	(	(	-LRB-
cord-008530-yni0poh9	463	44	Westmoreland	Westmoreland	NNP
cord-008530-yni0poh9	463	45	et	et	NNP
cord-008530-yni0poh9	463	46	al	al	NNP
cord-008530-yni0poh9	463	47	.	.	NNP
cord-008530-yni0poh9	463	48	,	,	,
cord-008530-yni0poh9	463	49	1998	1998	CD
cord-008530-yni0poh9	463	50	)	)	-RRB-
cord-008530-yni0poh9	463	51	.	.	.
cord-008530-yni0poh9	464	1	In	in	IN
cord-008530-yni0poh9	464	2	addition	addition	NN
cord-008530-yni0poh9	464	3	,	,	,
cord-008530-yni0poh9	464	4	expression	expression	NN
cord-008530-yni0poh9	464	5	of	of	IN
cord-008530-yni0poh9	464	6	CCR3	CCR3	NNP
cord-008530-yni0poh9	464	7	,	,	,
cord-008530-yni0poh9	464	8	CCR5	CCR5	NNP
cord-008530-yni0poh9	464	9	,	,	,
cord-008530-yni0poh9	464	10	and	and	CC
cord-008530-yni0poh9	464	11	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	464	12	was	be	VBD
cord-008530-yni0poh9	464	13	detected	detect	VBN
cord-008530-yni0poh9	464	14	on	on	IN
cord-008530-yni0poh9	464	15	subpopulations	subpopulation	NNS
cord-008530-yni0poh9	464	16	of	of	IN
cord-008530-yni0poh9	464	17	large	large	JJ
cord-008530-yni0poh9	464	18	hippocampal	hippocampal	JJ
cord-008530-yni0poh9	464	19	and	and	CC
cord-008530-yni0poh9	464	20	neocortical	neocortical	JJ
cord-008530-yni0poh9	464	21	pyramidal	pyramidal	JJ
cord-008530-yni0poh9	464	22	neurons	neuron	NNS
cord-008530-yni0poh9	464	23	and	and	CC
cord-008530-yni0poh9	464	24	on	on	IN
cord-008530-yni0poh9	464	25	glial	glial	JJ
cord-008530-yni0poh9	464	26	cells	cell	NNS
cord-008530-yni0poh9	464	27	in	in	IN
cord-008530-yni0poh9	464	28	both	both	CC
cord-008530-yni0poh9	464	29	the	the	DT
cord-008530-yni0poh9	464	30	normal	normal	JJ
cord-008530-yni0poh9	464	31	and	and	CC
cord-008530-yni0poh9	464	32	the	the	DT
cord-008530-yni0poh9	464	33	SIV	SIV	NNP
cord-008530-yni0poh9	464	34	-	-	HYPH
cord-008530-yni0poh9	464	35	encephalitic	encephalitic	JJ
cord-008530-yni0poh9	464	36	brain	brain	NN
cord-008530-yni0poh9	464	37	.	.	.
cord-008530-yni0poh9	465	1	Again	again	RB
cord-008530-yni0poh9	465	2	,	,	,
cord-008530-yni0poh9	465	3	these	these	DT
cord-008530-yni0poh9	465	4	findings	finding	NNS
cord-008530-yni0poh9	465	5	show	show	VBP
cord-008530-yni0poh9	465	6	an	an	DT
cord-008530-yni0poh9	465	7	overlap	overlap	NN
cord-008530-yni0poh9	465	8	with	with	IN
cord-008530-yni0poh9	465	9	those	those	DT
cord-008530-yni0poh9	465	10	reported	report	VBN
cord-008530-yni0poh9	465	11	for	for	IN
cord-008530-yni0poh9	465	12	the	the	DT
cord-008530-yni0poh9	465	13	normal	normal	JJ
cord-008530-yni0poh9	465	14	and	and	CC
cord-008530-yni0poh9	465	15	the	the	DT
cord-008530-yni0poh9	465	16	HIV	HIV	NNP
cord-008530-yni0poh9	465	17	-	-	HYPH
cord-008530-yni0poh9	465	18	infected	infect	VBN
cord-008530-yni0poh9	465	19	brain	brain	NN
cord-008530-yni0poh9	465	20	in	in	IN
cord-008530-yni0poh9	465	21	humans	human	NNS
cord-008530-yni0poh9	465	22	(	(	-LRB-
cord-008530-yni0poh9	465	23	as	as	IN
cord-008530-yni0poh9	465	24	noted	note	VBN
cord-008530-yni0poh9	465	25	above	above	RB
cord-008530-yni0poh9	465	26	)	)	-RRB-
cord-008530-yni0poh9	465	27	.	.	.
cord-008530-yni0poh9	466	1	M	M	NNP
cord-008530-yni0poh9	466	2	-	-	HYPH
cord-008530-yni0poh9	466	3	tropic	tropic	JJ
cord-008530-yni0poh9	466	4	strains	strain	NNS
cord-008530-yni0poh9	466	5	of	of	IN
cord-008530-yni0poh9	466	6	SIV	SIV	NNP
cord-008530-yni0poh9	466	7	utilize	utilize	VB
cord-008530-yni0poh9	466	8	CCR5	CCR5	NNP
cord-008530-yni0poh9	466	9	as	as	IN
cord-008530-yni0poh9	466	10	a	a	DT
cord-008530-yni0poh9	466	11	coreceptor	coreceptor	NN
cord-008530-yni0poh9	466	12	with	with	IN
cord-008530-yni0poh9	466	13	CD4	CD4	NNP
cord-008530-yni0poh9	466	14	for	for	IN
cord-008530-yni0poh9	466	15	infection	infection	NN
cord-008530-yni0poh9	466	16	of	of	IN
cord-008530-yni0poh9	466	17	macrophages	macrophage	NNS
cord-008530-yni0poh9	466	18	Deng	Deng	NNP
cord-008530-yni0poh9	466	19	et	et	FW
cord-008530-yni0poh9	466	20	al	al	NNP
cord-008530-yni0poh9	466	21	.	.	NNP
cord-008530-yni0poh9	466	22	,	,	,
cord-008530-yni0poh9	466	23	1997	1997	CD
cord-008530-yni0poh9	466	24	)	)	-RRB-
cord-008530-yni0poh9	466	25	.	.	.
cord-008530-yni0poh9	467	1	Expression	expression	NN
cord-008530-yni0poh9	467	2	of	of	IN
cord-008530-yni0poh9	467	3	CCR5	CCR5	NNP
cord-008530-yni0poh9	467	4	is	be	VBZ
cord-008530-yni0poh9	467	5	enriched	enrich	VBN
cord-008530-yni0poh9	467	6	on	on	IN
cord-008530-yni0poh9	467	7	microglial	microglial	JJ
cord-008530-yni0poh9	467	8	cells	cell	NNS
cord-008530-yni0poh9	467	9	in	in	IN
cord-008530-yni0poh9	467	10	the	the	DT
cord-008530-yni0poh9	467	11	macaque	macaque	NN
cord-008530-yni0poh9	467	12	brain	brain	NN
cord-008530-yni0poh9	467	13	and	and	CC
cord-008530-yni0poh9	467	14	may	may	MD
cord-008530-yni0poh9	467	15	therefore	therefore	RB
cord-008530-yni0poh9	467	16	provide	provide	VB
cord-008530-yni0poh9	467	17	the	the	DT
cord-008530-yni0poh9	467	18	molecular	molecular	JJ
cord-008530-yni0poh9	467	19	framework	framework	NN
cord-008530-yni0poh9	467	20	for	for	IN
cord-008530-yni0poh9	467	21	infection	infection	NN
cord-008530-yni0poh9	467	22	by	by	IN
cord-008530-yni0poh9	467	23	SIV	SIV	NNP
cord-008530-yni0poh9	467	24	in	in	IN
cord-008530-yni0poh9	467	25	the	the	DT
cord-008530-yni0poh9	467	26	monkey	monkey	NN
cord-008530-yni0poh9	467	27	CNS	CNS	NNP
cord-008530-yni0poh9	467	28	.	.	.
cord-008530-yni0poh9	468	1	Overall	overall	RB
cord-008530-yni0poh9	468	2	,	,	,
cord-008530-yni0poh9	468	3	the	the	DT
cord-008530-yni0poh9	468	4	preceding	precede	VBG
cord-008530-yni0poh9	468	5	discussion	discussion	NN
cord-008530-yni0poh9	468	6	highlights	highlight	VBZ
cord-008530-yni0poh9	468	7	the	the	DT
cord-008530-yni0poh9	468	8	overlapping	overlap	VBG
cord-008530-yni0poh9	468	9	expression	expression	NN
cord-008530-yni0poh9	468	10	patterns	pattern	NNS
cord-008530-yni0poh9	468	11	and	and	CC
cord-008530-yni0poh9	468	12	potentially	potentially	RB
cord-008530-yni0poh9	468	13	similar	similar	JJ
cord-008530-yni0poh9	468	14	roles	role	NNS
cord-008530-yni0poh9	468	15	for	for	IN
cord-008530-yni0poh9	468	16	the	the	DT
cord-008530-yni0poh9	468	17	chemokines	chemokine	NNS
cord-008530-yni0poh9	468	18	and	and	CC
cord-008530-yni0poh9	468	19	their	-PRON-	PRP$
cord-008530-yni0poh9	468	20	receptors	receptor	NNS
cord-008530-yni0poh9	468	21	in	in	IN
cord-008530-yni0poh9	468	22	the	the	DT
cord-008530-yni0poh9	468	23	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	468	24	of	of	IN
cord-008530-yni0poh9	468	25	SIV	SIV	NNP
cord-008530-yni0poh9	468	26	-	-	:
cord-008530-yni0poh9	468	27	encephalitis	encephalitis	NNP
cord-008530-yni0poh9	468	28	and	and	CC
cord-008530-yni0poh9	468	29	neu	neu	NNP
cord-008530-yni0poh9	468	30	-	-	HYPH
cord-008530-yni0poh9	468	31	roAIDS	roAIDS	NNP
cord-008530-yni0poh9	468	32	.	.	.
cord-008530-yni0poh9	469	1	This	this	DT
cord-008530-yni0poh9	469	2	idea	idea	NN
cord-008530-yni0poh9	469	3	is	be	VBZ
cord-008530-yni0poh9	469	4	further	far	RBR
cord-008530-yni0poh9	469	5	underscored	underscore	VBN
cord-008530-yni0poh9	469	6	by	by	IN
cord-008530-yni0poh9	469	7	a	a	DT
cord-008530-yni0poh9	469	8	recent	recent	JJ
cord-008530-yni0poh9	469	9	study	study	NN
cord-008530-yni0poh9	469	10	in	in	IN
cord-008530-yni0poh9	469	11	which	which	WDT
cord-008530-yni0poh9	469	12	chemokine	chemokine	NN
cord-008530-yni0poh9	469	13	receptor	receptor	NN
cord-008530-yni0poh9	469	14	expression	expression	NN
cord-008530-yni0poh9	469	15	and	and	CC
cord-008530-yni0poh9	469	16	signaling	signaling	NN
cord-008530-yni0poh9	469	17	were	be	VBD
cord-008530-yni0poh9	469	18	examined	examine	VBN
cord-008530-yni0poh9	469	19	in	in	IN
cord-008530-yni0poh9	469	20	cultured	cultured	JJ
cord-008530-yni0poh9	469	21	neurons	neuron	NNS
cord-008530-yni0poh9	469	22	derived	derive	VBN
cord-008530-yni0poh9	469	23	from	from	IN
cord-008530-yni0poh9	469	24	either	either	DT
cord-008530-yni0poh9	469	25	macaque	macaque	JJ
cord-008530-yni0poh9	469	26	or	or	CC
cord-008530-yni0poh9	469	27	human	human	JJ
cord-008530-yni0poh9	469	28	brains	brain	NNS
cord-008530-yni0poh9	469	29	(	(	-LRB-
cord-008530-yni0poh9	469	30	Klein	Klein	NNP
cord-008530-yni0poh9	469	31	et	et	NNP
cord-008530-yni0poh9	469	32	al	al	NNP
cord-008530-yni0poh9	469	33	.	.	NNP
cord-008530-yni0poh9	469	34	,	,	,
cord-008530-yni0poh9	469	35	1999	1999	CD
cord-008530-yni0poh9	469	36	)	)	-RRB-
cord-008530-yni0poh9	469	37	.	.	.
cord-008530-yni0poh9	470	1	Thus	thus	RB
cord-008530-yni0poh9	470	2	,	,	,
cord-008530-yni0poh9	470	3	both	both	CC
cord-008530-yni0poh9	470	4	the	the	DT
cord-008530-yni0poh9	470	5	qualitative	qualitative	JJ
cord-008530-yni0poh9	470	6	pattern	pattern	NN
cord-008530-yni0poh9	470	7	of	of	IN
cord-008530-yni0poh9	470	8	expression	expression	NN
cord-008530-yni0poh9	470	9	and	and	CC
cord-008530-yni0poh9	470	10	the	the	DT
cord-008530-yni0poh9	470	11	functional	functional	JJ
cord-008530-yni0poh9	470	12	behavior	behavior	NN
cord-008530-yni0poh9	470	13	of	of	IN
cord-008530-yni0poh9	470	14	the	the	DT
cord-008530-yni0poh9	470	15	chemokine	chemokine	NN
cord-008530-yni0poh9	470	16	receptors	receptor	NNS
cord-008530-yni0poh9	470	17	,	,	,
cord-008530-yni0poh9	470	18	CCR3	CCR3	NNP
cord-008530-yni0poh9	470	19	,	,	,
cord-008530-yni0poh9	470	20	CCR5	CCR5	NNP
cord-008530-yni0poh9	470	21	,	,	,
cord-008530-yni0poh9	470	22	and	and	CC
cord-008530-yni0poh9	470	23	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	470	24	,	,	,
cord-008530-yni0poh9	470	25	in	in	IN
cord-008530-yni0poh9	470	26	the	the	DT
cord-008530-yni0poh9	470	27	two	two	CD
cord-008530-yni0poh9	470	28	species	specie	NNS
cord-008530-yni0poh9	470	29	are	be	VBP
cord-008530-yni0poh9	470	30	remarkably	remarkably	RB
cord-008530-yni0poh9	470	31	alike	alike	RB
cord-008530-yni0poh9	470	32	.	.	.
cord-008530-yni0poh9	471	1	In	in	IN
cord-008530-yni0poh9	471	2	humans	human	NNS
cord-008530-yni0poh9	471	3	,	,	,
cord-008530-yni0poh9	471	4	multiple	multiple	JJ
cord-008530-yni0poh9	471	5	sclerosis	sclerosis	NN
cord-008530-yni0poh9	471	6	is	be	VBZ
cord-008530-yni0poh9	471	7	the	the	DT
cord-008530-yni0poh9	471	8	most	most	RBS
cord-008530-yni0poh9	471	9	common	common	JJ
cord-008530-yni0poh9	471	10	and	and	CC
cord-008530-yni0poh9	471	11	the	the	DT
cord-008530-yni0poh9	471	12	bestknown	bestknown	JJS
cord-008530-yni0poh9	471	13	CNS	CNS	NNP
cord-008530-yni0poh9	471	14	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	471	15	disorder	disorder	NN
cord-008530-yni0poh9	471	16	.	.	.
cord-008530-yni0poh9	472	1	MS	MS	NNP
cord-008530-yni0poh9	472	2	is	be	VBZ
cord-008530-yni0poh9	472	3	thought	think	VBN
cord-008530-yni0poh9	472	4	to	to	TO
cord-008530-yni0poh9	472	5	be	be	VB
cord-008530-yni0poh9	472	6	an	an	DT
cord-008530-yni0poh9	472	7	autoim	autoim	NN
cord-008530-yni0poh9	472	8	-	-	HYPH
cord-008530-yni0poh9	472	9	mune	mune	NNP
cord-008530-yni0poh9	472	10	T	T	NNP
cord-008530-yni0poh9	472	11	-	-	HYPH
cord-008530-yni0poh9	472	12	cell	cell	NN
cord-008530-yni0poh9	472	13	-	-	HYPH
cord-008530-yni0poh9	472	14	mediated	mediate	VBN
cord-008530-yni0poh9	472	15	disease	disease	NN
cord-008530-yni0poh9	472	16	that	that	WDT
cord-008530-yni0poh9	472	17	is	be	VBZ
cord-008530-yni0poh9	472	18	targeted	target	VBN
cord-008530-yni0poh9	472	19	at	at	IN
cord-008530-yni0poh9	472	20	the	the	DT
cord-008530-yni0poh9	472	21	myelin	myelin	NN
cord-008530-yni0poh9	472	22	sheath	sheath	NN
cord-008530-yni0poh9	472	23	.	.	.
cord-008530-yni0poh9	473	1	The	the	DT
cord-008530-yni0poh9	473	2	etiology	etiology	NN
cord-008530-yni0poh9	473	3	of	of	IN
cord-008530-yni0poh9	473	4	MS	MS	NNP
cord-008530-yni0poh9	473	5	is	be	VBZ
cord-008530-yni0poh9	473	6	unknown	unknown	JJ
cord-008530-yni0poh9	473	7	(	(	-LRB-
cord-008530-yni0poh9	473	8	Hailer	Hailer	NNP
cord-008530-yni0poh9	473	9	,	,	,
cord-008530-yni0poh9	473	10	1999	1999	CD
cord-008530-yni0poh9	473	11	)	)	-RRB-
cord-008530-yni0poh9	473	12	,	,	,
cord-008530-yni0poh9	473	13	although	although	IN
cord-008530-yni0poh9	473	14	at	at	IN
cord-008530-yni0poh9	473	15	one	one	CD
cord-008530-yni0poh9	473	16	time	time	NN
cord-008530-yni0poh9	473	17	or	or	CC
cord-008530-yni0poh9	473	18	another	another	DT
cord-008530-yni0poh9	473	19	,	,	,
cord-008530-yni0poh9	473	20	different	different	JJ
cord-008530-yni0poh9	473	21	viruses	virus	NNS
cord-008530-yni0poh9	473	22	have	have	VBP
cord-008530-yni0poh9	473	23	been	be	VBN
cord-008530-yni0poh9	473	24	implicated	implicate	VBN
cord-008530-yni0poh9	473	25	in	in	IN
cord-008530-yni0poh9	473	26	its	-PRON-	PRP$
cord-008530-yni0poh9	473	27	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	473	28	,	,	,
cord-008530-yni0poh9	473	29	including	include	VBG
cord-008530-yni0poh9	473	30	Epstein	Epstein	NNP
cord-008530-yni0poh9	473	31	-	-	HYPH
cord-008530-yni0poh9	473	32	Barr	Barr	NNP
cord-008530-yni0poh9	473	33	virus	virus	NN
cord-008530-yni0poh9	473	34	(	(	-LRB-
cord-008530-yni0poh9	473	35	EBV	EBV	NNP
cord-008530-yni0poh9	473	36	)	)	-RRB-
cord-008530-yni0poh9	473	37	,	,	,
cord-008530-yni0poh9	473	38	measles	measles	NN
cord-008530-yni0poh9	473	39	virus	virus	NN
cord-008530-yni0poh9	473	40	,	,	,
cord-008530-yni0poh9	473	41	and	and	CC
cord-008530-yni0poh9	473	42	recently	recently	RB
cord-008530-yni0poh9	473	43	,	,	,
cord-008530-yni0poh9	473	44	HHV-6	HHV-6	NNP
cord-008530-yni0poh9	473	45	.	.	.
cord-008530-yni0poh9	474	1	The	the	DT
cord-008530-yni0poh9	474	2	human	human	JJ
cord-008530-yni0poh9	474	3	T	T	NNP
cord-008530-yni0poh9	474	4	lymphotropic	lymphotropic	NNP
cord-008530-yni0poh9	474	5	virus	virus	NN
cord-008530-yni0poh9	474	6	type	type	NN
cord-008530-yni0poh9	474	7	I	-PRON-	PRP
cord-008530-yni0poh9	474	8	(	(	-LRB-
cord-008530-yni0poh9	474	9	HTLV-1	HTLV-1	NNP
cord-008530-yni0poh9	474	10	)	)	-RRB-
cord-008530-yni0poh9	474	11	infection	infection	NN
cord-008530-yni0poh9	474	12	of	of	IN
cord-008530-yni0poh9	474	13	the	the	DT
cord-008530-yni0poh9	474	14	CNS	CNS	NNP
cord-008530-yni0poh9	474	15	can	can	MD
cord-008530-yni0poh9	474	16	cause	cause	VB
cord-008530-yni0poh9	474	17	a	a	DT
cord-008530-yni0poh9	474	18	progressive	progressive	JJ
cord-008530-yni0poh9	474	19	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	474	20	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	474	21	disease	disease	NN
cord-008530-yni0poh9	474	22	and	and	CC
cord-008530-yni0poh9	474	23	shares	share	NNS
cord-008530-yni0poh9	474	24	many	many	JJ
cord-008530-yni0poh9	474	25	similarities	similarity	NNS
cord-008530-yni0poh9	474	26	with	with	IN
cord-008530-yni0poh9	474	27	MS	MS	NNP
cord-008530-yni0poh9	474	28	.	.	.
cord-008530-yni0poh9	475	1	In	in	IN
cord-008530-yni0poh9	475	2	view	view	NN
cord-008530-yni0poh9	475	3	of	of	IN
cord-008530-yni0poh9	475	4	a	a	DT
cord-008530-yni0poh9	475	5	possible	possible	JJ
cord-008530-yni0poh9	475	6	viral	viral	JJ
cord-008530-yni0poh9	475	7	role	role	NN
cord-008530-yni0poh9	475	8	in	in	IN
cord-008530-yni0poh9	475	9	MS	MS	NNP
cord-008530-yni0poh9	475	10	,	,	,
cord-008530-yni0poh9	475	11	research	research	NN
cord-008530-yni0poh9	475	12	has	have	VBZ
cord-008530-yni0poh9	475	13	focused	focus	VBN
cord-008530-yni0poh9	475	14	on	on	IN
cord-008530-yni0poh9	475	15	several	several	JJ
cord-008530-yni0poh9	475	16	experimental	experimental	JJ
cord-008530-yni0poh9	475	17	viral	viral	JJ
cord-008530-yni0poh9	475	18	models	model	NNS
cord-008530-yni0poh9	475	19	associated	associate	VBN
cord-008530-yni0poh9	475	20	with	with	IN
cord-008530-yni0poh9	475	21	the	the	DT
cord-008530-yni0poh9	475	22	development	development	NN
cord-008530-yni0poh9	475	23	of	of	IN
cord-008530-yni0poh9	475	24	neuroimmune	neuroimmune	NNP
cord-008530-yni0poh9	475	25	responses	response	NNS
cord-008530-yni0poh9	475	26	and	and	CC
cord-008530-yni0poh9	475	27	primary	primary	JJ
cord-008530-yni0poh9	475	28	demyelination	demyelination	NN
cord-008530-yni0poh9	475	29	that	that	WDT
cord-008530-yni0poh9	475	30	show	show	VBP
cord-008530-yni0poh9	475	31	many	many	JJ
cord-008530-yni0poh9	475	32	clinicopathologic	clinicopathologic	JJ
cord-008530-yni0poh9	475	33	similarities	similarity	NNS
cord-008530-yni0poh9	475	34	with	with	IN
cord-008530-yni0poh9	475	35	MS	MS	NNP
cord-008530-yni0poh9	475	36	.	.	.
cord-008530-yni0poh9	476	1	Among	among	IN
cord-008530-yni0poh9	476	2	the	the	DT
cord-008530-yni0poh9	476	3	best	well	RBS
cord-008530-yni0poh9	476	4	-	-	HYPH
cord-008530-yni0poh9	476	5	known	know	VBN
cord-008530-yni0poh9	476	6	and	and	CC
cord-008530-yni0poh9	476	7	most	most	RBS
cord-008530-yni0poh9	476	8	widely	widely	RB
cord-008530-yni0poh9	476	9	studied	study	VBN
cord-008530-yni0poh9	476	10	of	of	IN
cord-008530-yni0poh9	476	11	these	these	DT
cord-008530-yni0poh9	476	12	experimental	experimental	JJ
cord-008530-yni0poh9	476	13	models	model	NNS
cord-008530-yni0poh9	476	14	are	be	VBP
cord-008530-yni0poh9	476	15	Theiler	Theiler	NNP
cord-008530-yni0poh9	476	16	's	's	POS
cord-008530-yni0poh9	476	17	murine	murine	JJ
cord-008530-yni0poh9	476	18	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	476	19	virus	virus	NN
cord-008530-yni0poh9	476	20	(	(	-LRB-
cord-008530-yni0poh9	476	21	TMEV)-and	TMEV)-and	NNP
cord-008530-yni0poh9	476	22	murine	murine	JJ
cord-008530-yni0poh9	476	23	hepatitis	hepatitis	NN
cord-008530-yni0poh9	476	24	virus	virus	NN
cord-008530-yni0poh9	476	25	(	(	-LRB-
cord-008530-yni0poh9	476	26	MHV)-induced	mhv)-induce	VBN
cord-008530-yni0poh9	476	27	demyelinating	demyelinating	NN
cord-008530-yni0poh9	476	28	disease	disease	NN
cord-008530-yni0poh9	476	29	.	.	.
cord-008530-yni0poh9	477	1	HTLV-1	HTLV-1	NNP
cord-008530-yni0poh9	477	2	is	be	VBZ
cord-008530-yni0poh9	477	3	the	the	DT
cord-008530-yni0poh9	477	4	etiologic	etiologic	JJ
cord-008530-yni0poh9	477	5	agent	agent	NN
cord-008530-yni0poh9	477	6	for	for	IN
cord-008530-yni0poh9	477	7	adult	adult	NN
cord-008530-yni0poh9	477	8	T	T	NNP
cord-008530-yni0poh9	477	9	cell	cell	NN
cord-008530-yni0poh9	477	10	leukemia	leukemia	NN
cord-008530-yni0poh9	477	11	(	(	-LRB-
cord-008530-yni0poh9	477	12	ATL	ATL	NNP
cord-008530-yni0poh9	477	13	)	)	-RRB-
cord-008530-yni0poh9	477	14	and	and	CC
cord-008530-yni0poh9	477	15	for	for	IN
cord-008530-yni0poh9	477	16	HAM	HAM	NNP
cord-008530-yni0poh9	477	17	/	/	SYM
cord-008530-yni0poh9	477	18	TSP	tsp	NN
cord-008530-yni0poh9	477	19	,	,	,
cord-008530-yni0poh9	477	20	which	which	WDT
cord-008530-yni0poh9	477	21	shows	show	VBZ
cord-008530-yni0poh9	477	22	similar	similar	JJ
cord-008530-yni0poh9	477	23	features	feature	NNS
cord-008530-yni0poh9	477	24	to	to	IN
cord-008530-yni0poh9	477	25	primary	primary	JJ
cord-008530-yni0poh9	477	26	progressive	progressive	JJ
cord-008530-yni0poh9	477	27	MS	MS	NNP
cord-008530-yni0poh9	478	1	(	(	-LRB-
cord-008530-yni0poh9	478	2	Calabresi	Calabresi	NNP
cord-008530-yni0poh9	478	3	et	et	NNP
cord-008530-yni0poh9	478	4	al	al	NNP
cord-008530-yni0poh9	478	5	.	.	NNP
cord-008530-yni0poh9	478	6	,	,	,
cord-008530-yni0poh9	478	7	1999	1999	CD
cord-008530-yni0poh9	478	8	)	)	-RRB-
cord-008530-yni0poh9	478	9	.	.	.
cord-008530-yni0poh9	479	1	HAM	HAM	NNP
cord-008530-yni0poh9	479	2	-	-	HYPH
cord-008530-yni0poh9	479	3	TSP	tsp	NN
cord-008530-yni0poh9	479	4	is	be	VBZ
cord-008530-yni0poh9	479	5	a	a	DT
cord-008530-yni0poh9	479	6	chronic	chronic	JJ
cord-008530-yni0poh9	479	7	progressive	progressive	JJ
cord-008530-yni0poh9	479	8	neurological	neurological	JJ
cord-008530-yni0poh9	479	9	disorder	disorder	NN
cord-008530-yni0poh9	479	10	characterized	characterize	VBN
cord-008530-yni0poh9	479	11	by	by	IN
cord-008530-yni0poh9	479	12	a	a	DT
cord-008530-yni0poh9	479	13	perivascular	perivascular	JJ
cord-008530-yni0poh9	479	14	demyelination	demyelination	NN
cord-008530-yni0poh9	479	15	and	and	CC
cord-008530-yni0poh9	479	16	axonal	axonal	JJ
cord-008530-yni0poh9	479	17	degeneration	degeneration	NN
cord-008530-yni0poh9	479	18	,	,	,
cord-008530-yni0poh9	479	19	along	along	IN
cord-008530-yni0poh9	479	20	with	with	IN
cord-008530-yni0poh9	479	21	the	the	DT
cord-008530-yni0poh9	479	22	presence	presence	NN
cord-008530-yni0poh9	479	23	of	of	IN
cord-008530-yni0poh9	479	24	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	479	25	infiltrating	infiltrate	VBG
cord-008530-yni0poh9	479	26	cells	cell	NNS
cord-008530-yni0poh9	479	27	such	such	JJ
cord-008530-yni0poh9	479	28	as	as	IN
cord-008530-yni0poh9	479	29	macrophages	macrophage	NNS
cord-008530-yni0poh9	479	30	and	and	CC
cord-008530-yni0poh9	479	31	CD8	CD8	NNP
cord-008530-yni0poh9	479	32	÷	÷	NNP
cord-008530-yni0poh9	479	33	T	T	NNP
cord-008530-yni0poh9	479	34	cells	cell	NNS
cord-008530-yni0poh9	479	35	in	in	IN
cord-008530-yni0poh9	479	36	the	the	DT
cord-008530-yni0poh9	479	37	damaged	damage	VBN
cord-008530-yni0poh9	479	38	areas	area	NNS
cord-008530-yni0poh9	480	1	(	(	-LRB-
cord-008530-yni0poh9	480	2	Moore	Moore	NNP
cord-008530-yni0poh9	480	3	et	et	NNP
cord-008530-yni0poh9	480	4	al	al	NNP
cord-008530-yni0poh9	480	5	.	.	NNP
cord-008530-yni0poh9	480	6	,	,	,
cord-008530-yni0poh9	480	7	1989	1989	CD
cord-008530-yni0poh9	480	8	;	;	:
cord-008530-yni0poh9	481	1	Umehara	Umehara	NNP
cord-008530-yni0poh9	481	2	et	et	NNP
cord-008530-yni0poh9	481	3	al	al	NNP
cord-008530-yni0poh9	481	4	.	.	NNP
cord-008530-yni0poh9	481	5	,	,	,
cord-008530-yni0poh9	481	6	1993	1993	CD
cord-008530-yni0poh9	481	7	;	;	:
cord-008530-yni0poh9	481	8	Wu	Wu	NNP
cord-008530-yni0poh9	481	9	et	et	NNP
cord-008530-yni0poh9	481	10	al	al	NNP
cord-008530-yni0poh9	481	11	.	.	NNP
cord-008530-yni0poh9	481	12	,	,	,
cord-008530-yni0poh9	481	13	1993	1993	CD
cord-008530-yni0poh9	481	14	)	)	-RRB-
cord-008530-yni0poh9	481	15	.	.	.
cord-008530-yni0poh9	482	1	These	these	DT
cord-008530-yni0poh9	482	2	infiltrating	infiltrate	VBG
cord-008530-yni0poh9	482	3	cells	cell	NNS
cord-008530-yni0poh9	482	4	produce	produce	VBP
cord-008530-yni0poh9	482	5	several	several	JJ
cord-008530-yni0poh9	482	6	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	482	7	mediators	mediator	NNS
cord-008530-yni0poh9	482	8	including	include	VBG
cord-008530-yni0poh9	482	9	the	the	DT
cord-008530-yni0poh9	482	10	chemokine	chemokine	NN
cord-008530-yni0poh9	482	11	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	483	1	(	(	-LRB-
cord-008530-yni0poh9	483	2	Umehara	Umehara	NNP
cord-008530-yni0poh9	483	3	et	et	NNP
cord-008530-yni0poh9	483	4	al	al	NNP
cord-008530-yni0poh9	483	5	.	.	NNP
cord-008530-yni0poh9	483	6	,	,	,
cord-008530-yni0poh9	483	7	1993	1993	CD
cord-008530-yni0poh9	483	8	)	)	-RRB-
cord-008530-yni0poh9	483	9	.	.	.
cord-008530-yni0poh9	484	1	In	in	IN
cord-008530-yni0poh9	484	2	addition	addition	NN
cord-008530-yni0poh9	484	3	,	,	,
cord-008530-yni0poh9	484	4	HTLV-1infected	HTLV-1infected	NNP
cord-008530-yni0poh9	484	5	T	T	NNP
cord-008530-yni0poh9	484	6	cell	cell	NN
cord-008530-yni0poh9	484	7	lines	line	NNS
cord-008530-yni0poh9	484	8	produce	produce	VBP
cord-008530-yni0poh9	484	9	a	a	DT
cord-008530-yni0poh9	484	10	number	number	NN
cord-008530-yni0poh9	484	11	of	of	IN
cord-008530-yni0poh9	484	12	chemokines	chemokine	NNS
cord-008530-yni0poh9	484	13	including	include	VBG
cord-008530-yni0poh9	484	14	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	484	15	,	,	,
cord-008530-yni0poh9	484	16	RANTES	RANTES	NNP
cord-008530-yni0poh9	484	17	,	,	,
cord-008530-yni0poh9	484	18	MIP	MIP	NNP
cord-008530-yni0poh9	484	19	-	-	HYPH
cord-008530-yni0poh9	484	20	la	la	NNP
cord-008530-yni0poh9	484	21	,	,	,
cord-008530-yni0poh9	484	22	and	and	CC
cord-008530-yni0poh9	484	23	MIP	MIP	NNP
cord-008530-yni0poh9	484	24	-	-	HYPH
cord-008530-yni0poh9	484	25	I~	I~	NNP
cord-008530-yni0poh9	485	1	(	(	-LRB-
cord-008530-yni0poh9	485	2	Arai	Arai	NNP
cord-008530-yni0poh9	485	3	et	et	NNP
cord-008530-yni0poh9	485	4	al	al	NNP
cord-008530-yni0poh9	485	5	.	.	NNP
cord-008530-yni0poh9	485	6	,	,	,
cord-008530-yni0poh9	485	7	1998	1998	CD
cord-008530-yni0poh9	486	1	;	;	:
cord-008530-yni0poh9	486	2	Baba	Baba	NNP
cord-008530-yni0poh9	486	3	et	et	NNP
cord-008530-yni0poh9	486	4	al	al	NNP
cord-008530-yni0poh9	486	5	.	.	NNP
cord-008530-yni0poh9	486	6	,	,	,
cord-008530-yni0poh9	486	7	1996	1996	CD
cord-008530-yni0poh9	486	8	;	;	:
cord-008530-yni0poh9	486	9	Mendez	Mendez	NNP
cord-008530-yni0poh9	486	10	et	et	NNP
cord-008530-yni0poh9	486	11	al	al	NNP
cord-008530-yni0poh9	486	12	.	.	NNP
cord-008530-yni0poh9	486	13	,	,	,
cord-008530-yni0poh9	486	14	1997	1997	CD
cord-008530-yni0poh9	486	15	)	)	-RRB-
cord-008530-yni0poh9	486	16	.	.	.
cord-008530-yni0poh9	487	1	HAM	HAM	NNP
cord-008530-yni0poh9	487	2	/	/	SYM
cord-008530-yni0poh9	487	3	TSP	tsp	NN
cord-008530-yni0poh9	487	4	patients	patient	NNS
cord-008530-yni0poh9	487	5	have	have	VBP
cord-008530-yni0poh9	487	6	a	a	DT
cord-008530-yni0poh9	487	7	high	high	JJ
cord-008530-yni0poh9	487	8	frequency	frequency	NN
cord-008530-yni0poh9	487	9	of	of	IN
cord-008530-yni0poh9	487	10	CD8	CD8	NNP
cord-008530-yni0poh9	487	11	÷	÷	NNP
cord-008530-yni0poh9	487	12	CTL	CTL	NNP
cord-008530-yni0poh9	487	13	in	in	IN
cord-008530-yni0poh9	487	14	their	-PRON-	PRP$
cord-008530-yni0poh9	487	15	peripheral	peripheral	JJ
cord-008530-yni0poh9	487	16	blood	blood	NN
cord-008530-yni0poh9	487	17	and	and	CC
cord-008530-yni0poh9	487	18	cerebrospinal	cerebrospinal	NN
cord-008530-yni0poh9	487	19	fluid	fluid	NN
cord-008530-yni0poh9	487	20	(	(	-LRB-
cord-008530-yni0poh9	487	21	CSF	CSF	NNP
cord-008530-yni0poh9	487	22	)	)	-RRB-
cord-008530-yni0poh9	487	23	.	.	.
cord-008530-yni0poh9	488	1	Biddison	Biddison	NNP
cord-008530-yni0poh9	488	2	and	and	CC
cord-008530-yni0poh9	488	3	coworkers	coworker	NNS
cord-008530-yni0poh9	488	4	have	have	VBP
cord-008530-yni0poh9	488	5	shown	show	VBN
cord-008530-yni0poh9	488	6	that	that	IN
cord-008530-yni0poh9	488	7	HTLV	HTLV	NNP
cord-008530-yni0poh9	488	8	-	-	HYPH
cord-008530-yni0poh9	488	9	I	i	NN
cord-008530-yni0poh9	488	10	-	-	HYPH
cord-008530-yni0poh9	488	11	specific	specific	JJ
cord-008530-yni0poh9	488	12	CD8	CD8	NNP
cord-008530-yni0poh9	488	13	÷	÷	NNP
cord-008530-yni0poh9	488	14	CTL	CTL	NNP
cord-008530-yni0poh9	488	15	clones	clone	NNS
cord-008530-yni0poh9	488	16	secrete	secrete	VBP
cord-008530-yni0poh9	488	17	MIP	MIP	NNP
cord-008530-yni0poh9	488	18	-	-	HYPH
cord-008530-yni0poh9	488	19	la	la	NNP
cord-008530-yni0poh9	488	20	,	,	,
cord-008530-yni0poh9	488	21	MIP	MIP	NNP
cord-008530-yni0poh9	488	22	-	-	HYPH
cord-008530-yni0poh9	488	23	I~	I~	NNP
cord-008530-yni0poh9	488	24	,	,	,
cord-008530-yni0poh9	488	25	and	and	CC
cord-008530-yni0poh9	488	26	IL-16	IL-16	NNP
cord-008530-yni0poh9	488	27	(	(	-LRB-
cord-008530-yni0poh9	488	28	Biddison	Biddison	NNP
cord-008530-yni0poh9	488	29	et	et	NNP
cord-008530-yni0poh9	488	30	al	al	NNP
cord-008530-yni0poh9	488	31	.	.	NNP
cord-008530-yni0poh9	488	32	,	,	,
cord-008530-yni0poh9	488	33	1997	1997	CD
cord-008530-yni0poh9	488	34	)	)	-RRB-
cord-008530-yni0poh9	488	35	.	.	.
cord-008530-yni0poh9	489	1	Thus	thus	RB
cord-008530-yni0poh9	489	2	,	,	,
cord-008530-yni0poh9	489	3	these	these	DT
cord-008530-yni0poh9	489	4	HTLV-1	HTLV-1	NNP
cord-008530-yni0poh9	489	5	CTLs	ctl	NNS
cord-008530-yni0poh9	489	6	may	may	MD
cord-008530-yni0poh9	489	7	be	be	VB
cord-008530-yni0poh9	489	8	an	an	DT
cord-008530-yni0poh9	489	9	important	important	JJ
cord-008530-yni0poh9	489	10	source	source	NN
cord-008530-yni0poh9	489	11	of	of	IN
cord-008530-yni0poh9	489	12	chemokines	chemokine	NNS
cord-008530-yni0poh9	489	13	in	in	IN
cord-008530-yni0poh9	489	14	HAM	HAM	NNP
cord-008530-yni0poh9	489	15	/	/	SYM
cord-008530-yni0poh9	489	16	TSP	tsp	NN
cord-008530-yni0poh9	489	17	,	,	,
cord-008530-yni0poh9	489	18	where	where	WRB
cord-008530-yni0poh9	489	19	they	-PRON-	PRP
cord-008530-yni0poh9	489	20	might	may	MD
cord-008530-yni0poh9	489	21	contribute	contribute	VB
cord-008530-yni0poh9	489	22	to	to	IN
cord-008530-yni0poh9	489	23	the	the	DT
cord-008530-yni0poh9	489	24	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	489	25	of	of	IN
cord-008530-yni0poh9	489	26	this	this	DT
cord-008530-yni0poh9	489	27	disorder	disorder	NN
cord-008530-yni0poh9	489	28	.	.	.
cord-008530-yni0poh9	490	1	Consistent	consistent	JJ
cord-008530-yni0poh9	490	2	with	with	IN
cord-008530-yni0poh9	490	3	this	this	DT
cord-008530-yni0poh9	490	4	,	,	,
cord-008530-yni0poh9	490	5	elevated	elevated	JJ
cord-008530-yni0poh9	490	6	MIP	MIP	NNP
cord-008530-yni0poh9	490	7	-	-	HYPH
cord-008530-yni0poh9	490	8	la	la	NNP
cord-008530-yni0poh9	490	9	protein	protein	NN
cord-008530-yni0poh9	490	10	was	be	VBD
cord-008530-yni0poh9	490	11	found	find	VBN
cord-008530-yni0poh9	490	12	in	in	IN
cord-008530-yni0poh9	490	13	the	the	DT
cord-008530-yni0poh9	490	14	CSF	CSF	NNP
cord-008530-yni0poh9	490	15	in	in	IN
cord-008530-yni0poh9	490	16	two	two	CD
cord-008530-yni0poh9	490	17	of	of	IN
cord-008530-yni0poh9	490	18	three	three	CD
cord-008530-yni0poh9	490	19	patients	patient	NNS
cord-008530-yni0poh9	490	20	with	with	IN
cord-008530-yni0poh9	490	21	HAM	HAM	NNP
cord-008530-yni0poh9	490	22	/	/	SYM
cord-008530-yni0poh9	490	23	TSP	tsp	NN
cord-008530-yni0poh9	490	24	(	(	-LRB-
cord-008530-yni0poh9	490	25	Miyagishi	Miyagishi	NNP
cord-008530-yni0poh9	490	26	et	et	NNP
cord-008530-yni0poh9	490	27	al	al	NNP
cord-008530-yni0poh9	490	28	.	.	NNP
cord-008530-yni0poh9	490	29	,	,	,
cord-008530-yni0poh9	490	30	1995	1995	CD
cord-008530-yni0poh9	490	31	)	)	-RRB-
cord-008530-yni0poh9	490	32	.	.	.
cord-008530-yni0poh9	491	1	A	a	DT
cord-008530-yni0poh9	491	2	further	further	JJ
cord-008530-yni0poh9	491	3	clinical	clinical	JJ
cord-008530-yni0poh9	491	4	study	study	NN
cord-008530-yni0poh9	491	5	showed	show	VBD
cord-008530-yni0poh9	491	6	that	that	IN
cord-008530-yni0poh9	491	7	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	491	8	was	be	VBD
cord-008530-yni0poh9	491	9	detectable	detectable	JJ
cord-008530-yni0poh9	491	10	on	on	IN
cord-008530-yni0poh9	491	11	perivascular	perivascular	JJ
cord-008530-yni0poh9	491	12	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	491	13	cells	cell	NNS
cord-008530-yni0poh9	491	14	and	and	CC
cord-008530-yni0poh9	491	15	the	the	DT
cord-008530-yni0poh9	491	16	vascular	vascular	JJ
cord-008530-yni0poh9	491	17	endothelium	endothelium	NN
cord-008530-yni0poh9	491	18	in	in	IN
cord-008530-yni0poh9	491	19	active	active	JJ
cord-008530-yni0poh9	491	20	-	-	HYPH
cord-008530-yni0poh9	491	21	chronic	chronic	JJ
cord-008530-yni0poh9	491	22	lesions	lesion	NNS
cord-008530-yni0poh9	491	23	of	of	IN
cord-008530-yni0poh9	491	24	spinal	spinal	JJ
cord-008530-yni0poh9	491	25	cords	cord	NNS
cord-008530-yni0poh9	491	26	of	of	IN
cord-008530-yni0poh9	491	27	HAM	ham	NN
cord-008530-yni0poh9	491	28	/	/	SYM
cord-008530-yni0poh9	491	29	TSP	tsp	NN
cord-008530-yni0poh9	491	30	patients	patient	NNS
cord-008530-yni0poh9	492	1	(	(	-LRB-
cord-008530-yni0poh9	492	2	Umehara	Umehara	NNP
cord-008530-yni0poh9	492	3	et	et	NNP
cord-008530-yni0poh9	492	4	al	al	NNP
cord-008530-yni0poh9	492	5	.	.	NNP
cord-008530-yni0poh9	492	6	,	,	,
cord-008530-yni0poh9	492	7	1996	1996	CD
cord-008530-yni0poh9	492	8	)	)	-RRB-
cord-008530-yni0poh9	492	9	.	.	.
cord-008530-yni0poh9	493	1	MHV	MHV	NNP
cord-008530-yni0poh9	493	2	belongs	belong	VBZ
cord-008530-yni0poh9	493	3	to	to	IN
cord-008530-yni0poh9	493	4	the	the	DT
cord-008530-yni0poh9	493	5	coronaviruses	coronaviruse	NNS
cord-008530-yni0poh9	493	6	,	,	,
cord-008530-yni0poh9	493	7	a	a	DT
cord-008530-yni0poh9	493	8	ubiquitous	ubiquitous	JJ
cord-008530-yni0poh9	493	9	group	group	NN
cord-008530-yni0poh9	493	10	of	of	IN
cord-008530-yni0poh9	493	11	positivestranded	positivestranded	NNP
cord-008530-yni0poh9	493	12	RNA	RNA	NNP
cord-008530-yni0poh9	493	13	viral	viral	JJ
cord-008530-yni0poh9	493	14	pathogens	pathogen	NNS
cord-008530-yni0poh9	493	15	of	of	IN
cord-008530-yni0poh9	493	16	man	man	NN
cord-008530-yni0poh9	493	17	and	and	CC
cord-008530-yni0poh9	493	18	animals	animal	NNS
cord-008530-yni0poh9	493	19	associated	associate	VBN
cord-008530-yni0poh9	493	20	with	with	IN
cord-008530-yni0poh9	493	21	a	a	DT
cord-008530-yni0poh9	493	22	variety	variety	NN
cord-008530-yni0poh9	493	23	of	of	IN
cord-008530-yni0poh9	493	24	respiratory	respiratory	JJ
cord-008530-yni0poh9	493	25	,	,	,
cord-008530-yni0poh9	493	26	gastrointestinal	gastrointestinal	JJ
cord-008530-yni0poh9	493	27	,	,	,
cord-008530-yni0poh9	493	28	and	and	CC
cord-008530-yni0poh9	493	29	neurological	neurological	JJ
cord-008530-yni0poh9	493	30	disorders	disorder	NNS
cord-008530-yni0poh9	493	31	.	.	.
cord-008530-yni0poh9	494	1	VAL]~RIE	VAL]~RIE	NNP
cord-008530-yni0poh9	494	2	C.	C.	NNP
cord-008530-yni0poh9	494	3	ASENSIO	ASENSIO	NNP
cord-008530-yni0poh9	494	4	AND	and	CC
cord-008530-yni0poh9	495	1	IAIN	IAIN	NNP
cord-008530-yni0poh9	495	2	L.	L.	NNP
cord-008530-yni0poh9	495	3	CAMPBELL	CAMPBELL	NNP
cord-008530-yni0poh9	495	4	CNS	CNS	NNP
cord-008530-yni0poh9	495	5	infection	infection	NN
cord-008530-yni0poh9	495	6	of	of	IN
cord-008530-yni0poh9	495	7	susceptible	susceptible	JJ
cord-008530-yni0poh9	495	8	murine	murine	JJ
cord-008530-yni0poh9	495	9	hosts	host	NNS
cord-008530-yni0poh9	495	10	with	with	IN
cord-008530-yni0poh9	495	11	neuro	neuro	NNP
cord-008530-yni0poh9	495	12	-	-	HYPH
cord-008530-yni0poh9	495	13	adapted	adapt	VBN
cord-008530-yni0poh9	495	14	strains	strain	NNS
cord-008530-yni0poh9	495	15	of	of	IN
cord-008530-yni0poh9	495	16	MHV	MHV	NNP
cord-008530-yni0poh9	495	17	leads	lead	VBZ
cord-008530-yni0poh9	495	18	to	to	IN
cord-008530-yni0poh9	495	19	a	a	DT
cord-008530-yni0poh9	495	20	robust	robust	JJ
cord-008530-yni0poh9	495	21	initial	initial	JJ
cord-008530-yni0poh9	495	22	recruitment	recruitment	NN
cord-008530-yni0poh9	495	23	of	of	IN
cord-008530-yni0poh9	495	24	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	495	25	to	to	IN
cord-008530-yni0poh9	495	26	the	the	DT
cord-008530-yni0poh9	495	27	brain	brain	NN
cord-008530-yni0poh9	495	28	that	that	WDT
cord-008530-yni0poh9	495	29	follows	follow	VBZ
cord-008530-yni0poh9	495	30	an	an	DT
cord-008530-yni0poh9	495	31	early	early	JJ
cord-008530-yni0poh9	495	32	peak	peak	NN
cord-008530-yni0poh9	495	33	of	of	IN
cord-008530-yni0poh9	495	34	viral	viral	JJ
cord-008530-yni0poh9	495	35	replication	replication	NN
cord-008530-yni0poh9	495	36	.	.	.
cord-008530-yni0poh9	496	1	This	this	DT
cord-008530-yni0poh9	496	2	acute	acute	JJ
cord-008530-yni0poh9	496	3	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	496	4	phase	phase	NN
cord-008530-yni0poh9	496	5	,	,	,
cord-008530-yni0poh9	496	6	with	with	IN
cord-008530-yni0poh9	496	7	its	-PRON-	PRP$
cord-008530-yni0poh9	496	8	resultant	resultant	JJ
cord-008530-yni0poh9	496	9	tissue	tissue	NN
cord-008530-yni0poh9	496	10	injury	injury	NN
cord-008530-yni0poh9	496	11	,	,	,
cord-008530-yni0poh9	496	12	often	often	RB
cord-008530-yni0poh9	496	13	leads	lead	VBZ
cord-008530-yni0poh9	496	14	to	to	IN
cord-008530-yni0poh9	496	15	death	death	NN
cord-008530-yni0poh9	496	16	of	of	IN
cord-008530-yni0poh9	496	17	the	the	DT
cord-008530-yni0poh9	496	18	host	host	NN
cord-008530-yni0poh9	496	19	.	.	.
cord-008530-yni0poh9	497	1	However	however	RB
cord-008530-yni0poh9	497	2	,	,	,
cord-008530-yni0poh9	497	3	in	in	IN
cord-008530-yni0poh9	497	4	surviving	survive	VBG
cord-008530-yni0poh9	497	5	animals	animal	NNS
cord-008530-yni0poh9	497	6	,	,	,
cord-008530-yni0poh9	497	7	further	further	JJ
cord-008530-yni0poh9	497	8	viral	viral	JJ
cord-008530-yni0poh9	497	9	replication	replication	NN
cord-008530-yni0poh9	497	10	is	be	VBZ
cord-008530-yni0poh9	497	11	controlled	control	VBN
cord-008530-yni0poh9	497	12	by	by	IN
cord-008530-yni0poh9	497	13	the	the	DT
cord-008530-yni0poh9	497	14	host	host	NN
cord-008530-yni0poh9	497	15	response	response	NN
cord-008530-yni0poh9	497	16	and	and	CC
cord-008530-yni0poh9	497	17	a	a	DT
cord-008530-yni0poh9	497	18	chronic	chronic	JJ
cord-008530-yni0poh9	497	19	mononuclear	mononuclear	JJ
cord-008530-yni0poh9	497	20	cell	cell	NN
cord-008530-yni0poh9	497	21	inflammation	inflammation	NN
cord-008530-yni0poh9	497	22	,	,	,
cord-008530-yni0poh9	497	23	which	which	WDT
cord-008530-yni0poh9	497	24	occurs	occur	VBZ
cord-008530-yni0poh9	497	25	in	in	IN
cord-008530-yni0poh9	497	26	the	the	DT
cord-008530-yni0poh9	497	27	brain	brain	NN
cord-008530-yni0poh9	497	28	and	and	CC
cord-008530-yni0poh9	497	29	spinal	spinal	JJ
cord-008530-yni0poh9	497	30	cord	cord	NN
cord-008530-yni0poh9	497	31	,	,	,
cord-008530-yni0poh9	497	32	is	be	VBZ
cord-008530-yni0poh9	497	33	linked	link	VBN
cord-008530-yni0poh9	497	34	to	to	IN
cord-008530-yni0poh9	497	35	a	a	DT
cord-008530-yni0poh9	497	36	progressive	progressive	JJ
cord-008530-yni0poh9	497	37	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	497	38	disease	disease	NN
cord-008530-yni0poh9	497	39	(	(	-LRB-
cord-008530-yni0poh9	497	40	Buchmeier	Buchmeier	NNP
cord-008530-yni0poh9	497	41	and	and	CC
cord-008530-yni0poh9	497	42	Lane	Lane	NNP
cord-008530-yni0poh9	497	43	,	,	,
cord-008530-yni0poh9	497	44	1999	1999	CD
cord-008530-yni0poh9	497	45	;	;	:
cord-008530-yni0poh9	497	46	Lane	Lane	NNP
cord-008530-yni0poh9	497	47	and	and	CC
cord-008530-yni0poh9	497	48	Buchmeier	Buchmeier	NNP
cord-008530-yni0poh9	497	49	,	,	,
cord-008530-yni0poh9	497	50	1997	1997	CD
cord-008530-yni0poh9	497	51	;	;	:
cord-008530-yni0poh9	497	52	Weiner	Weiner	NNP
cord-008530-yni0poh9	497	53	,	,	,
cord-008530-yni0poh9	497	54	1973	1973	CD
cord-008530-yni0poh9	497	55	)	)	-RRB-
cord-008530-yni0poh9	497	56	.	.	.
cord-008530-yni0poh9	498	1	The	the	DT
cord-008530-yni0poh9	498	2	mechanisms	mechanism	NNS
cord-008530-yni0poh9	498	3	of	of	IN
cord-008530-yni0poh9	498	4	demyelination	demyelination	NN
cord-008530-yni0poh9	498	5	in	in	IN
cord-008530-yni0poh9	498	6	this	this	DT
cord-008530-yni0poh9	498	7	model	model	NN
cord-008530-yni0poh9	498	8	are	be	VBP
cord-008530-yni0poh9	498	9	not	not	RB
cord-008530-yni0poh9	498	10	clear	clear	JJ
cord-008530-yni0poh9	498	11	,	,	,
cord-008530-yni0poh9	498	12	although	although	IN
cord-008530-yni0poh9	498	13	there	there	EX
cord-008530-yni0poh9	498	14	is	be	VBZ
cord-008530-yni0poh9	498	15	a	a	DT
cord-008530-yni0poh9	498	16	requirement	requirement	NN
cord-008530-yni0poh9	498	17	for	for	IN
cord-008530-yni0poh9	498	18	a	a	DT
cord-008530-yni0poh9	498	19	competent	competent	JJ
cord-008530-yni0poh9	498	20	immune	immune	JJ
cord-008530-yni0poh9	498	21	response	response	NN
cord-008530-yni0poh9	498	22	.	.	.
cord-008530-yni0poh9	499	1	In	in	IN
cord-008530-yni0poh9	499	2	a	a	DT
cord-008530-yni0poh9	499	3	study	study	NN
cord-008530-yni0poh9	499	4	of	of	IN
cord-008530-yni0poh9	499	5	the	the	DT
cord-008530-yni0poh9	499	6	kinetics	kinetic	NNS
cord-008530-yni0poh9	499	7	and	and	CC
cord-008530-yni0poh9	499	8	histological	histological	JJ
cord-008530-yni0poh9	499	9	localization	localization	NN
cord-008530-yni0poh9	499	10	of	of	IN
cord-008530-yni0poh9	499	11	chemokine	chemokine	NN
cord-008530-yni0poh9	499	12	gene	gene	NN
cord-008530-yni0poh9	499	13	expression	expression	NN
cord-008530-yni0poh9	499	14	in	in	IN
cord-008530-yni0poh9	499	15	the	the	DT
cord-008530-yni0poh9	499	16	brain	brain	NN
cord-008530-yni0poh9	499	17	and	and	CC
cord-008530-yni0poh9	499	18	spinal	spinal	JJ
cord-008530-yni0poh9	499	19	cord	cord	NN
cord-008530-yni0poh9	499	20	of	of	IN
cord-008530-yni0poh9	499	21	MHV	MHV	NNP
cord-008530-yni0poh9	499	22	-	-	HYPH
cord-008530-yni0poh9	499	23	infected	infect	VBN
cord-008530-yni0poh9	499	24	mice	mouse	NNS
cord-008530-yni0poh9	499	25	,	,	,
cord-008530-yni0poh9	499	26	Lane	Lane	NNP
cord-008530-yni0poh9	499	27	and	and	CC
cord-008530-yni0poh9	499	28	colleagues	colleague	NNS
cord-008530-yni0poh9	499	29	showed	show	VBD
cord-008530-yni0poh9	499	30	that	that	IN
cord-008530-yni0poh9	499	31	a	a	DT
cord-008530-yni0poh9	499	32	number	number	NN
cord-008530-yni0poh9	499	33	of	of	IN
cord-008530-yni0poh9	499	34	a	a	DT
cord-008530-yni0poh9	499	35	-	-	:
cord-008530-yni0poh9	499	36	and	and	CC
cord-008530-yni0poh9	499	37	~-chemokines	~-chemokine	NNS
cord-008530-yni0poh9	499	38	were	be	VBD
cord-008530-yni0poh9	499	39	expressed	express	VBN
cord-008530-yni0poh9	499	40	during	during	IN
cord-008530-yni0poh9	499	41	acute	acute	JJ
cord-008530-yni0poh9	499	42	or	or	CC
cord-008530-yni0poh9	499	43	chronic	chronic	JJ
cord-008530-yni0poh9	499	44	stages	stage	NNS
cord-008530-yni0poh9	499	45	of	of	IN
cord-008530-yni0poh9	499	46	MHV	mhv	NN
cord-008530-yni0poh9	499	47	-	-	HYPH
cord-008530-yni0poh9	499	48	infection	infection	NN
cord-008530-yni0poh9	499	49	(	(	-LRB-
cord-008530-yni0poh9	499	50	Lane	Lane	NNP
cord-008530-yni0poh9	499	51	et	et	NNP
cord-008530-yni0poh9	499	52	al	al	NNP
cord-008530-yni0poh9	499	53	.	.	NNP
cord-008530-yni0poh9	499	54	,	,	,
cord-008530-yni0poh9	499	55	1998	1998	CD
cord-008530-yni0poh9	499	56	)	)	-RRB-
cord-008530-yni0poh9	499	57	.	.	.
cord-008530-yni0poh9	500	1	Expression	expression	NN
cord-008530-yni0poh9	500	2	of	of	IN
cord-008530-yni0poh9	500	3	the	the	DT
cord-008530-yni0poh9	500	4	transcripts	transcript	NNS
cord-008530-yni0poh9	500	5	for	for	IN
cord-008530-yni0poh9	500	6	IP-10	IP-10	NNP
cord-008530-yni0poh9	500	7	,	,	,
cord-008530-yni0poh9	500	8	MIP-2	MIP-2	NNP
cord-008530-yni0poh9	500	9	,	,	,
cord-008530-yni0poh9	500	10	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	500	11	,	,	,
cord-008530-yni0poh9	500	12	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	500	13	,	,	,
cord-008530-yni0poh9	500	14	MIP-1~	MIP-1~	NNP
cord-008530-yni0poh9	500	15	,	,	,
cord-008530-yni0poh9	500	16	and	and	CC
cord-008530-yni0poh9	500	17	RANTES	rante	NNS
cord-008530-yni0poh9	500	18	overlapped	overlap	VBN
cord-008530-yni0poh9	500	19	with	with	IN
cord-008530-yni0poh9	500	20	the	the	DT
cord-008530-yni0poh9	500	21	occurrence	occurrence	NN
cord-008530-yni0poh9	500	22	of	of	IN
cord-008530-yni0poh9	500	23	acute	acute	JJ
cord-008530-yni0poh9	500	24	viral	viral	JJ
cord-008530-yni0poh9	500	25	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	500	26	,	,	,
cord-008530-yni0poh9	500	27	being	be	VBG
cord-008530-yni0poh9	500	28	present	present	JJ
cord-008530-yni0poh9	500	29	by	by	IN
cord-008530-yni0poh9	500	30	day	day	NN
cord-008530-yni0poh9	500	31	3	3	CD
cord-008530-yni0poh9	500	32	postinfection	postinfection	NN
cord-008530-yni0poh9	500	33	and	and	CC
cord-008530-yni0poh9	500	34	peaking	peak	VBG
cord-008530-yni0poh9	500	35	at	at	IN
cord-008530-yni0poh9	500	36	day	day	NN
cord-008530-yni0poh9	500	37	7	7	CD
cord-008530-yni0poh9	500	38	postinfection	postinfection	NN
cord-008530-yni0poh9	500	39	.	.	.
cord-008530-yni0poh9	501	1	During	during	IN
cord-008530-yni0poh9	501	2	the	the	DT
cord-008530-yni0poh9	501	3	chronic	chronic	JJ
cord-008530-yni0poh9	501	4	demyelinating	demyelinating	NN
cord-008530-yni0poh9	501	5	phase	phase	NN
cord-008530-yni0poh9	501	6	of	of	IN
cord-008530-yni0poh9	501	7	the	the	DT
cord-008530-yni0poh9	501	8	disease	disease	NN
cord-008530-yni0poh9	501	9	,	,	,
cord-008530-yni0poh9	501	10	both	both	CC
cord-008530-yni0poh9	501	11	IP-10	IP-10	NNP
cord-008530-yni0poh9	501	12	and	and	CC
cord-008530-yni0poh9	501	13	RANTES	RANTES	NNP
cord-008530-yni0poh9	501	14	transcripts	transcript	NNS
cord-008530-yni0poh9	501	15	remained	remain	VBD
cord-008530-yni0poh9	501	16	elevated	elevated	JJ
cord-008530-yni0poh9	501	17	.	.	.
cord-008530-yni0poh9	502	1	IP-10	IP-10	NNP
cord-008530-yni0poh9	503	1	RNA	RNA	NNP
cord-008530-yni0poh9	503	2	colocalized	colocalize	VBN
cord-008530-yni0poh9	503	3	with	with	IN
cord-008530-yni0poh9	503	4	viral	viral	JJ
cord-008530-yni0poh9	503	5	RNA	RNA	NNP
cord-008530-yni0poh9	503	6	and	and	CC
cord-008530-yni0poh9	503	7	was	be	VBD
cord-008530-yni0poh9	503	8	present	present	JJ
cord-008530-yni0poh9	503	9	in	in	IN
cord-008530-yni0poh9	503	10	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	503	11	and	and	CC
cord-008530-yni0poh9	503	12	microglia	microglia	NN
cord-008530-yni0poh9	503	13	associated	associate	VBN
cord-008530-yni0poh9	503	14	with	with	IN
cord-008530-yni0poh9	503	15	demyelinating	demyelinating	JJ
cord-008530-yni0poh9	503	16	lesions	lesion	NNS
cord-008530-yni0poh9	503	17	(	(	-LRB-
cord-008530-yni0poh9	503	18	Lane	Lane	NNP
cord-008530-yni0poh9	503	19	et	et	NNP
cord-008530-yni0poh9	503	20	al	al	NNP
cord-008530-yni0poh9	503	21	.	.	NNP
cord-008530-yni0poh9	503	22	,	,	,
cord-008530-yni0poh9	503	23	1998	1998	CD
cord-008530-yni0poh9	503	24	)	)	-RRB-
cord-008530-yni0poh9	503	25	.	.	.
cord-008530-yni0poh9	504	1	With	with	IN
cord-008530-yni0poh9	504	2	the	the	DT
cord-008530-yni0poh9	504	3	exception	exception	NN
cord-008530-yni0poh9	504	4	of	of	IN
cord-008530-yni0poh9	504	5	RANTES	RANTES	NNP
cord-008530-yni0poh9	504	6	,	,	,
cord-008530-yni0poh9	504	7	a	a	DT
cord-008530-yni0poh9	504	8	similar	similar	JJ
cord-008530-yni0poh9	504	9	pattern	pattern	NN
cord-008530-yni0poh9	504	10	of	of	IN
cord-008530-yni0poh9	504	11	chemokine	chemokine	JJ
cord-008530-yni0poh9	504	12	expression	expression	NN
cord-008530-yni0poh9	504	13	was	be	VBD
cord-008530-yni0poh9	504	14	observed	observe	VBN
cord-008530-yni0poh9	504	15	with	with	IN
cord-008530-yni0poh9	504	16	cultured	cultured	JJ
cord-008530-yni0poh9	504	17	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	504	18	infected	infect	VBN
cord-008530-yni0poh9	504	19	with	with	IN
cord-008530-yni0poh9	504	20	active	active	JJ
cord-008530-yni0poh9	504	21	,	,	,
cord-008530-yni0poh9	504	22	but	but	CC
cord-008530-yni0poh9	504	23	not	not	RB
cord-008530-yni0poh9	504	24	UV	uv	NN
cord-008530-yni0poh9	504	25	-	-	HYPH
cord-008530-yni0poh9	504	26	inactive	inactive	JJ
cord-008530-yni0poh9	504	27	,	,	,
cord-008530-yni0poh9	504	28	MHV	MHV	NNP
cord-008530-yni0poh9	504	29	,	,	,
cord-008530-yni0poh9	504	30	indicating	indicate	VBG
cord-008530-yni0poh9	504	31	that	that	IN
cord-008530-yni0poh9	504	32	viral	viral	JJ
cord-008530-yni0poh9	504	33	replication	replication	NN
cord-008530-yni0poh9	504	34	in	in	IN
cord-008530-yni0poh9	504	35	these	these	DT
cord-008530-yni0poh9	504	36	cells	cell	NNS
cord-008530-yni0poh9	504	37	can	can	MD
cord-008530-yni0poh9	504	38	directly	directly	RB
cord-008530-yni0poh9	504	39	stimulate	stimulate	VB
cord-008530-yni0poh9	504	40	chemokine	chemokine	NN
cord-008530-yni0poh9	504	41	gene	gene	NN
cord-008530-yni0poh9	504	42	expression	expression	NN
cord-008530-yni0poh9	504	43	.	.	.
cord-008530-yni0poh9	505	1	Therefore	therefore	RB
cord-008530-yni0poh9	505	2	,	,	,
cord-008530-yni0poh9	505	3	in	in	IN
cord-008530-yni0poh9	505	4	MHV	MHV	NNP
cord-008530-yni0poh9	505	5	infection	infection	NN
cord-008530-yni0poh9	505	6	of	of	IN
cord-008530-yni0poh9	505	7	the	the	DT
cord-008530-yni0poh9	505	8	brain	brain	NN
cord-008530-yni0poh9	505	9	,	,	,
cord-008530-yni0poh9	505	10	early	early	JJ
cord-008530-yni0poh9	505	11	viral	viral	RB
cord-008530-yni0poh9	505	12	-	-	HYPH
cord-008530-yni0poh9	505	13	induced	induce	VBN
cord-008530-yni0poh9	505	14	chemokine	chemokine	NN
cord-008530-yni0poh9	505	15	gene	gene	NN
cord-008530-yni0poh9	505	16	expression	expression	NN
cord-008530-yni0poh9	505	17	by	by	IN
cord-008530-yni0poh9	505	18	resident	resident	JJ
cord-008530-yni0poh9	505	19	CNS	CNS	NNP
cord-008530-yni0poh9	505	20	cells	cell	NNS
cord-008530-yni0poh9	505	21	such	such	JJ
cord-008530-yni0poh9	505	22	as	as	IN
cord-008530-yni0poh9	505	23	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	505	24	might	may	MD
cord-008530-yni0poh9	505	25	promote	promote	VB
cord-008530-yni0poh9	505	26	the	the	DT
cord-008530-yni0poh9	505	27	recruitment	recruitment	NN
cord-008530-yni0poh9	505	28	of	of	IN
cord-008530-yni0poh9	505	29	T	T	NNP
cord-008530-yni0poh9	505	30	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	505	31	and	and	CC
cord-008530-yni0poh9	505	32	macrophages	macrophage	NNS
cord-008530-yni0poh9	505	33	and	and	CC
cord-008530-yni0poh9	505	34	contribute	contribute	VB
cord-008530-yni0poh9	505	35	to	to	IN
cord-008530-yni0poh9	505	36	the	the	DT
cord-008530-yni0poh9	505	37	maintenance	maintenance	NN
cord-008530-yni0poh9	505	38	of	of	IN
cord-008530-yni0poh9	505	39	the	the	DT
cord-008530-yni0poh9	505	40	chronic	chronic	JJ
cord-008530-yni0poh9	505	41	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	505	42	response	response	NN
cord-008530-yni0poh9	505	43	leading	lead	VBG
cord-008530-yni0poh9	505	44	to	to	IN
cord-008530-yni0poh9	505	45	demyelination	demyelination	NN
cord-008530-yni0poh9	505	46	.	.	.
cord-008530-yni0poh9	506	1	Further	further	JJ
cord-008530-yni0poh9	506	2	studies	study	NNS
cord-008530-yni0poh9	506	3	in	in	IN
cord-008530-yni0poh9	506	4	the	the	DT
cord-008530-yni0poh9	506	5	MHV	MHV	NNP
cord-008530-yni0poh9	506	6	model	model	NN
cord-008530-yni0poh9	506	7	using	use	VBG
cord-008530-yni0poh9	506	8	CD4	CD4	NNP
cord-008530-yni0poh9	506	9	KO	KO	NNP
cord-008530-yni0poh9	506	10	and	and	CC
cord-008530-yni0poh9	506	11	CD8	CD8	NNP
cord-008530-yni0poh9	506	12	KO	KO	NNP
cord-008530-yni0poh9	506	13	mice	mouse	NNS
cord-008530-yni0poh9	506	14	show	show	VBP
cord-008530-yni0poh9	506	15	an	an	DT
cord-008530-yni0poh9	506	16	important	important	JJ
cord-008530-yni0poh9	506	17	role	role	NN
cord-008530-yni0poh9	506	18	for	for	IN
cord-008530-yni0poh9	506	19	CD4	CD4	NNP
cord-008530-yni0poh9	506	20	÷	÷	NNP
cord-008530-yni0poh9	506	21	T	T	NNP
cord-008530-yni0poh9	506	22	-	-	HYPH
cord-008530-yni0poh9	506	23	cells	cell	NNS
cord-008530-yni0poh9	506	24	in	in	IN
cord-008530-yni0poh9	506	25	the	the	DT
cord-008530-yni0poh9	506	26	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	506	27	of	of	IN
cord-008530-yni0poh9	506	28	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	506	29	disease	disease	NN
cord-008530-yni0poh9	506	30	and	and	CC
cord-008530-yni0poh9	506	31	demyelination	demyelination	NN
cord-008530-yni0poh9	506	32	(	(	-LRB-
cord-008530-yni0poh9	506	33	Lane	Lane	NNP
cord-008530-yni0poh9	506	34	et	et	NNP
cord-008530-yni0poh9	506	35	al	al	NNP
cord-008530-yni0poh9	506	36	.	.	NNP
cord-008530-yni0poh9	506	37	,	,	,
cord-008530-yni0poh9	506	38	2000	2000	CD
cord-008530-yni0poh9	506	39	)	)	-RRB-
cord-008530-yni0poh9	506	40	.	.	.
cord-008530-yni0poh9	507	1	Thus	thus	RB
cord-008530-yni0poh9	507	2	,	,	,
cord-008530-yni0poh9	507	3	MHVinfected	MHVinfected	NNP
cord-008530-yni0poh9	507	4	CD4	CD4	NNP
cord-008530-yni0poh9	507	5	KO	KO	NNP
cord-008530-yni0poh9	507	6	mice	mouse	NNS
cord-008530-yni0poh9	507	7	have	have	VBP
cord-008530-yni0poh9	507	8	a	a	DT
cord-008530-yni0poh9	507	9	marked	marked	JJ
cord-008530-yni0poh9	507	10	reduction	reduction	NN
cord-008530-yni0poh9	507	11	in	in	IN
cord-008530-yni0poh9	507	12	the	the	DT
cord-008530-yni0poh9	507	13	number	number	NN
cord-008530-yni0poh9	507	14	of	of	IN
cord-008530-yni0poh9	507	15	activated	activate	VBN
cord-008530-yni0poh9	507	16	macrophage	macrophage	NN
cord-008530-yni0poh9	507	17	/	/	SYM
cord-008530-yni0poh9	507	18	microglia	microglia	NNS
cord-008530-yni0poh9	507	19	within	within	IN
cord-008530-yni0poh9	507	20	their	-PRON-	PRP$
cord-008530-yni0poh9	507	21	brains	brain	NNS
cord-008530-yni0poh9	507	22	and	and	CC
cord-008530-yni0poh9	507	23	spinal	spinal	JJ
cord-008530-yni0poh9	507	24	cords	cord	NNS
cord-008530-yni0poh9	507	25	and	and	CC
cord-008530-yni0poh9	507	26	significantly	significantly	RB
cord-008530-yni0poh9	507	27	less	less	JJR
cord-008530-yni0poh9	507	28	demyelination	demyelination	NN
cord-008530-yni0poh9	507	29	.	.	.
cord-008530-yni0poh9	508	1	Concomitant	concomitant	JJ
cord-008530-yni0poh9	508	2	with	with	IN
cord-008530-yni0poh9	508	3	the	the	DT
cord-008530-yni0poh9	508	4	reduction	reduction	NN
cord-008530-yni0poh9	508	5	in	in	IN
cord-008530-yni0poh9	508	6	CNS	CNS	NNP
cord-008530-yni0poh9	508	7	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	508	8	disease	disease	NN
cord-008530-yni0poh9	508	9	in	in	IN
cord-008530-yni0poh9	508	10	the	the	DT
cord-008530-yni0poh9	508	11	MHV	MHV	NNP
cord-008530-yni0poh9	508	12	-	-	HYPH
cord-008530-yni0poh9	508	13	infected	infect	VBN
cord-008530-yni0poh9	508	14	CD4	CD4	NNP
cord-008530-yni0poh9	508	15	KO	KO	NNP
cord-008530-yni0poh9	508	16	mice	mouse	NNS
cord-008530-yni0poh9	508	17	,	,	,
cord-008530-yni0poh9	508	18	lower	low	JJR
cord-008530-yni0poh9	508	19	levels	level	NNS
cord-008530-yni0poh9	508	20	of	of	IN
cord-008530-yni0poh9	508	21	RANTES	rante	NNS
cord-008530-yni0poh9	508	22	,	,	,
cord-008530-yni0poh9	508	23	but	but	CC
cord-008530-yni0poh9	508	24	not	not	RB
cord-008530-yni0poh9	508	25	other	other	JJ
cord-008530-yni0poh9	508	26	chemokine	chemokine	NN
cord-008530-yni0poh9	508	27	transcripts	transcript	NNS
cord-008530-yni0poh9	508	28	and	and	CC
cord-008530-yni0poh9	508	29	protein	protein	NN
cord-008530-yni0poh9	508	30	were	be	VBD
cord-008530-yni0poh9	508	31	found	find	VBN
cord-008530-yni0poh9	508	32	indicating	indicate	VBG
cord-008530-yni0poh9	508	33	that	that	IN
cord-008530-yni0poh9	508	34	CD4	CD4	NNP
cord-008530-yni0poh9	508	35	÷	÷	NNP
cord-008530-yni0poh9	508	36	T	T	NNP
cord-008530-yni0poh9	508	37	-	-	HYPH
cord-008530-yni0poh9	508	38	cells	cell	NNS
cord-008530-yni0poh9	508	39	represent	represent	VBP
cord-008530-yni0poh9	508	40	one	one	CD
cord-008530-yni0poh9	508	41	major	major	JJ
cord-008530-yni0poh9	508	42	source	source	NN
cord-008530-yni0poh9	508	43	of	of	IN
cord-008530-yni0poh9	508	44	RANTES	rante	NNS
cord-008530-yni0poh9	508	45	in	in	IN
cord-008530-yni0poh9	508	46	the	the	DT
cord-008530-yni0poh9	508	47	CNS	CNS	NNP
cord-008530-yni0poh9	508	48	during	during	IN
cord-008530-yni0poh9	508	49	MHV	MHV	NNP
cord-008530-yni0poh9	508	50	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	508	51	.	.	.
cord-008530-yni0poh9	509	1	Administration	administration	NN
cord-008530-yni0poh9	509	2	of	of	IN
cord-008530-yni0poh9	509	3	RANTES	RANTES	NNP
cord-008530-yni0poh9	509	4	neutralizing	neutralize	VBG
cord-008530-yni0poh9	509	5	antisera	antisera	NN
cord-008530-yni0poh9	509	6	to	to	IN
cord-008530-yni0poh9	509	7	MHV	mhv	NN
cord-008530-yni0poh9	509	8	-	-	HYPH
cord-008530-yni0poh9	509	9	infected	infect	VBN
cord-008530-yni0poh9	509	10	mice	mouse	NNS
cord-008530-yni0poh9	509	11	is	be	VBZ
cord-008530-yni0poh9	509	12	associated	associate	VBN
cord-008530-yni0poh9	509	13	with	with	IN
cord-008530-yni0poh9	509	14	a	a	DT
cord-008530-yni0poh9	509	15	significant	significant	JJ
cord-008530-yni0poh9	509	16	reduction	reduction	NN
cord-008530-yni0poh9	509	17	in	in	IN
cord-008530-yni0poh9	509	18	macrophage	macrophage	NN
cord-008530-yni0poh9	509	19	infiltration	infiltration	NN
cord-008530-yni0poh9	509	20	and	and	CC
cord-008530-yni0poh9	509	21	demyelination	demyelination	NN
cord-008530-yni0poh9	509	22	compared	compare	VBN
cord-008530-yni0poh9	509	23	to	to	IN
cord-008530-yni0poh9	509	24	control	control	NN
cord-008530-yni0poh9	509	25	mice	mouse	NNS
cord-008530-yni0poh9	509	26	(	(	-LRB-
cord-008530-yni0poh9	509	27	Lane	Lane	NNP
cord-008530-yni0poh9	509	28	et	et	NNP
cord-008530-yni0poh9	509	29	al	al	NNP
cord-008530-yni0poh9	509	30	.	.	NNP
cord-008530-yni0poh9	509	31	,	,	,
cord-008530-yni0poh9	509	32	2000	2000	CD
cord-008530-yni0poh9	509	33	)	)	-RRB-
cord-008530-yni0poh9	509	34	.	.	.
cord-008530-yni0poh9	510	1	These	these	DT
cord-008530-yni0poh9	510	2	data	datum	NNS
cord-008530-yni0poh9	510	3	clearly	clearly	RB
cord-008530-yni0poh9	510	4	indicate	indicate	VBP
cord-008530-yni0poh9	510	5	that	that	IN
cord-008530-yni0poh9	510	6	CD4	CD4	NNP
cord-008530-yni0poh9	510	7	+	+	CC
cord-008530-yni0poh9	510	8	T	T	NNP
cord-008530-yni0poh9	510	9	-	-	HYPH
cord-008530-yni0poh9	510	10	cells	cell	NNS
cord-008530-yni0poh9	510	11	have	have	VBP
cord-008530-yni0poh9	510	12	a	a	DT
cord-008530-yni0poh9	510	13	pivotal	pivotal	JJ
cord-008530-yni0poh9	510	14	role	role	NN
cord-008530-yni0poh9	510	15	in	in	IN
cord-008530-yni0poh9	510	16	accelerating	accelerate	VBG
cord-008530-yni0poh9	510	17	CNS	CNS	NNP
cord-008530-yni0poh9	510	18	inflammation	inflammation	NN
cord-008530-yni0poh9	510	19	and	and	CC
cord-008530-yni0poh9	510	20	demyelination	demyelination	NN
cord-008530-yni0poh9	510	21	within	within	IN
cord-008530-yni0poh9	510	22	infected	infected	JJ
cord-008530-yni0poh9	510	23	mice	mouse	NNS
cord-008530-yni0poh9	510	24	possibly	possibly	RB
cord-008530-yni0poh9	510	25	by	by	IN
cord-008530-yni0poh9	510	26	regulating	regulate	VBG
cord-008530-yni0poh9	510	27	RANTES	RANTES	NNP
cord-008530-yni0poh9	510	28	expression	expression	NN
cord-008530-yni0poh9	510	29	.	.	.
cord-008530-yni0poh9	511	1	TMEV	TMEV	NNP
cord-008530-yni0poh9	511	2	-	-	HYPH
cord-008530-yni0poh9	511	3	induced	induce	VBN
cord-008530-yni0poh9	511	4	demyelinating	demyelinating	NN
cord-008530-yni0poh9	511	5	disease	disease	NN
cord-008530-yni0poh9	511	6	is	be	VBZ
cord-008530-yni0poh9	511	7	characterized	characterize	VBN
cord-008530-yni0poh9	511	8	by	by	IN
cord-008530-yni0poh9	511	9	CNS	CNS	NNP
cord-008530-yni0poh9	511	10	mononuclear	mononuclear	JJ
cord-008530-yni0poh9	511	11	cell	cell	NN
cord-008530-yni0poh9	511	12	infiltration	infiltration	NN
cord-008530-yni0poh9	511	13	resulting	result	VBG
cord-008530-yni0poh9	511	14	in	in	IN
cord-008530-yni0poh9	511	15	a	a	DT
cord-008530-yni0poh9	511	16	chronic	chronic	JJ
cord-008530-yni0poh9	511	17	CD4	CD4	NNP
cord-008530-yni0poh9	511	18	+	+	CC
cord-008530-yni0poh9	511	19	T	t	NN
cord-008530-yni0poh9	511	20	-	-	HYPH
cord-008530-yni0poh9	511	21	cell	cell	NN
cord-008530-yni0poh9	511	22	-	-	HYPH
cord-008530-yni0poh9	511	23	mediated	mediate	VBN
cord-008530-yni0poh9	511	24	demyelinating	demyelinating	NN
cord-008530-yni0poh9	511	25	disease	disease	NN
cord-008530-yni0poh9	511	26	(	(	-LRB-
cord-008530-yni0poh9	511	27	for	for	IN
cord-008530-yni0poh9	511	28	more	more	JJR
cord-008530-yni0poh9	511	29	discussion	discussion	NN
cord-008530-yni0poh9	511	30	,	,	,
cord-008530-yni0poh9	511	31	see	see	VB
cord-008530-yni0poh9	511	32	Chapter	chapter	NN
cord-008530-yni0poh9	511	33	7	7	CD
cord-008530-yni0poh9	511	34	in	in	IN
cord-008530-yni0poh9	511	35	this	this	DT
cord-008530-yni0poh9	511	36	volume	volume	NN
cord-008530-yni0poh9	511	37	)	)	-RRB-
cord-008530-yni0poh9	511	38	.	.	.
cord-008530-yni0poh9	512	1	A	a	DT
cord-008530-yni0poh9	512	2	study	study	NN
cord-008530-yni0poh9	512	3	of	of	IN
cord-008530-yni0poh9	512	4	the	the	DT
cord-008530-yni0poh9	512	5	expression	expression	NN
cord-008530-yni0poh9	512	6	of	of	IN
cord-008530-yni0poh9	512	7	CC	CC	NNP
cord-008530-yni0poh9	512	8	and	and	CC
cord-008530-yni0poh9	512	9	CXC	CXC	NNP
cord-008530-yni0poh9	512	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	512	11	in	in	IN
cord-008530-yni0poh9	512	12	the	the	DT
cord-008530-yni0poh9	512	13	CNS	CNS	NNP
cord-008530-yni0poh9	512	14	throughout	throughout	IN
cord-008530-yni0poh9	512	15	the	the	DT
cord-008530-yni0poh9	512	16	disease	disease	NN
cord-008530-yni0poh9	512	17	course	course	NN
cord-008530-yni0poh9	512	18	showed	show	VBD
cord-008530-yni0poh9	512	19	that	that	IN
cord-008530-yni0poh9	512	20	expression	expression	NN
cord-008530-yni0poh9	512	21	of	of	IN
cord-008530-yni0poh9	512	22	C10	C10	NNP
cord-008530-yni0poh9	512	23	,	,	,
cord-008530-yni0poh9	512	24	IP-10	IP-10	NNP
cord-008530-yni0poh9	512	25	,	,	,
cord-008530-yni0poh9	512	26	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	512	27	,	,	,
cord-008530-yni0poh9	512	28	MIP	MIP	NNP
cord-008530-yni0poh9	512	29	-	-	HYPH
cord-008530-yni0poh9	512	30	la	la	NNP
cord-008530-yni0poh9	512	31	,	,	,
cord-008530-yni0poh9	512	32	MIP	MIP	NNP
cord-008530-yni0poh9	512	33	-	-	HYPH
cord-008530-yni0poh9	512	34	I~	I~	NNP
cord-008530-yni0poh9	512	35	,	,	,
cord-008530-yni0poh9	512	36	and	and	CC
cord-008530-yni0poh9	512	37	RANTES	RANTES	NNP
cord-008530-yni0poh9	512	38	mRNA	mRNA	NNP
cord-008530-yni0poh9	512	39	transcripts	transcript	NNS
cord-008530-yni0poh9	512	40	overlapped	overlap	VBN
cord-008530-yni0poh9	512	41	with	with	IN
cord-008530-yni0poh9	512	42	the	the	DT
cord-008530-yni0poh9	512	43	development	development	NN
cord-008530-yni0poh9	512	44	of	of	IN
cord-008530-yni0poh9	512	45	disease	disease	NN
cord-008530-yni0poh9	512	46	(	(	-LRB-
cord-008530-yni0poh9	512	47	Hoffman	Hoffman	NNP
cord-008530-yni0poh9	512	48	et	et	NNP
cord-008530-yni0poh9	512	49	al	al	NNP
cord-008530-yni0poh9	512	50	.	.	NNP
cord-008530-yni0poh9	512	51	,	,	,
cord-008530-yni0poh9	512	52	1999	1999	CD
cord-008530-yni0poh9	512	53	)	)	-RRB-
cord-008530-yni0poh9	512	54	.	.	.
cord-008530-yni0poh9	513	1	Expression	expression	NN
cord-008530-yni0poh9	513	2	of	of	IN
cord-008530-yni0poh9	513	3	MIP	MIP	NNP
cord-008530-yni0poh9	513	4	-	-	HYPH
cord-008530-yni0poh9	513	5	I~	I~	NNP
cord-008530-yni0poh9	513	6	and	and	CC
cord-008530-yni0poh9	513	7	MIP	MIP	NNP
cord-008530-yni0poh9	513	8	-	-	HYPH
cord-008530-yni0poh9	513	9	I~	I~	NNP
cord-008530-yni0poh9	513	10	protein	protein	NN
cord-008530-yni0poh9	513	11	was	be	VBD
cord-008530-yni0poh9	513	12	also	also	RB
cord-008530-yni0poh9	513	13	detectable	detectable	JJ
cord-008530-yni0poh9	513	14	,	,	,
cord-008530-yni0poh9	513	15	being	be	VBG
cord-008530-yni0poh9	513	16	present	present	JJ
cord-008530-yni0poh9	513	17	in	in	IN
cord-008530-yni0poh9	513	18	the	the	DT
cord-008530-yni0poh9	513	19	spinal	spinal	JJ
cord-008530-yni0poh9	513	20	cord	cord	NN
cord-008530-yni0poh9	513	21	before	before	IN
cord-008530-yni0poh9	513	22	the	the	DT
cord-008530-yni0poh9	513	23	onset	onset	NN
cord-008530-yni0poh9	513	24	of	of	IN
cord-008530-yni0poh9	513	25	disease	disease	NN
cord-008530-yni0poh9	513	26	and	and	CC
cord-008530-yni0poh9	513	27	persisting	persist	VBG
cord-008530-yni0poh9	513	28	throughout	throughout	IN
cord-008530-yni0poh9	513	29	disease	disease	NN
cord-008530-yni0poh9	513	30	progression	progression	NN
cord-008530-yni0poh9	513	31	.	.	.
cord-008530-yni0poh9	514	1	These	these	DT
cord-008530-yni0poh9	514	2	findings	finding	NNS
cord-008530-yni0poh9	514	3	are	be	VBP
cord-008530-yni0poh9	514	4	somewhat	somewhat	RB
cord-008530-yni0poh9	514	5	reminiscent	reminiscent	JJ
cord-008530-yni0poh9	514	6	of	of	IN
cord-008530-yni0poh9	514	7	those	those	DT
cord-008530-yni0poh9	514	8	reported	report	VBN
cord-008530-yni0poh9	514	9	for	for	IN
cord-008530-yni0poh9	514	10	MHV	MHV	NNP
cord-008530-yni0poh9	514	11	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	514	12	(	(	-LRB-
cord-008530-yni0poh9	514	13	discussed	discuss	VBN
cord-008530-yni0poh9	514	14	above	above	RB
cord-008530-yni0poh9	514	15	)	)	-RRB-
cord-008530-yni0poh9	514	16	and	and	CC
cord-008530-yni0poh9	514	17	reiterate	reiterate	VB
cord-008530-yni0poh9	514	18	the	the	DT
cord-008530-yni0poh9	514	19	theme	theme	NN
cord-008530-yni0poh9	514	20	that	that	IN
cord-008530-yni0poh9	514	21	chemokine	chemokine	JJ
cord-008530-yni0poh9	514	22	expression	expression	NN
cord-008530-yni0poh9	514	23	in	in	IN
cord-008530-yni0poh9	514	24	these	these	DT
cord-008530-yni0poh9	514	25	viralinduced	viralinduce	VBN
cord-008530-yni0poh9	514	26	immune	immune	NN
cord-008530-yni0poh9	514	27	-	-	HYPH
cord-008530-yni0poh9	514	28	mediated	mediate	VBN
cord-008530-yni0poh9	514	29	demyelinating	demyelinating	NN
cord-008530-yni0poh9	514	30	diseases	disease	NNS
cord-008530-yni0poh9	514	31	is	be	VBZ
cord-008530-yni0poh9	514	32	a	a	DT
cord-008530-yni0poh9	514	33	complex	complex	JJ
cord-008530-yni0poh9	514	34	process	process	NN
cord-008530-yni0poh9	514	35	that	that	WDT
cord-008530-yni0poh9	514	36	is	be	VBZ
cord-008530-yni0poh9	514	37	clearly	clearly	RB
cord-008530-yni0poh9	514	38	associated	associate	VBN
cord-008530-yni0poh9	514	39	with	with	IN
cord-008530-yni0poh9	514	40	disease	disease	NN
cord-008530-yni0poh9	514	41	progression	progression	NN
cord-008530-yni0poh9	514	42	.	.	.
cord-008530-yni0poh9	515	1	Identifying	identify	VBG
cord-008530-yni0poh9	515	2	the	the	DT
cord-008530-yni0poh9	515	3	key	key	JJ
cord-008530-yni0poh9	515	4	chemokine	chemokine	NN
cord-008530-yni0poh9	515	5	protagonists	protagonist	NNS
cord-008530-yni0poh9	515	6	in	in	IN
cord-008530-yni0poh9	515	7	TMEV	TMEV	NNP
cord-008530-yni0poh9	515	8	-	-	HYPH
cord-008530-yni0poh9	515	9	induced	induce	VBN
cord-008530-yni0poh9	515	10	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	515	11	disease	disease	NN
cord-008530-yni0poh9	515	12	awaits	await	VBZ
cord-008530-yni0poh9	515	13	clarification	clarification	NN
cord-008530-yni0poh9	515	14	.	.	.
cord-008530-yni0poh9	516	1	Meningoencephalitis	Meningoencephalitis	NNP
cord-008530-yni0poh9	516	2	represents	represent	VBZ
cord-008530-yni0poh9	516	3	one	one	CD
cord-008530-yni0poh9	516	4	of	of	IN
cord-008530-yni0poh9	516	5	the	the	DT
cord-008530-yni0poh9	516	6	most	most	RBS
cord-008530-yni0poh9	516	7	devastating	devastating	JJ
cord-008530-yni0poh9	516	8	consequences	consequence	NNS
cord-008530-yni0poh9	516	9	of	of	IN
cord-008530-yni0poh9	516	10	viral	viral	JJ
cord-008530-yni0poh9	516	11	infection	infection	NN
cord-008530-yni0poh9	516	12	of	of	IN
cord-008530-yni0poh9	516	13	the	the	DT
cord-008530-yni0poh9	516	14	CNS	CNS	NNP
cord-008530-yni0poh9	516	15	,	,	,
cord-008530-yni0poh9	516	16	in	in	IN
cord-008530-yni0poh9	516	17	which	which	WDT
cord-008530-yni0poh9	516	18	a	a	DT
cord-008530-yni0poh9	516	19	concerted	concerted	JJ
cord-008530-yni0poh9	516	20	immunoinflammatory	immunoinflammatory	NNP
cord-008530-yni0poh9	516	21	response	response	NN
cord-008530-yni0poh9	516	22	by	by	IN
cord-008530-yni0poh9	516	23	the	the	DT
cord-008530-yni0poh9	516	24	host	host	NN
cord-008530-yni0poh9	516	25	produces	produce	VBZ
cord-008530-yni0poh9	516	26	severe	severe	JJ
cord-008530-yni0poh9	516	27	injury	injury	NN
cord-008530-yni0poh9	516	28	to	to	IN
cord-008530-yni0poh9	516	29	the	the	DT
cord-008530-yni0poh9	516	30	brain	brain	NN
cord-008530-yni0poh9	516	31	,	,	,
cord-008530-yni0poh9	516	32	leading	lead	VBG
cord-008530-yni0poh9	516	33	to	to	IN
cord-008530-yni0poh9	516	34	debilitating	debilitating	JJ
cord-008530-yni0poh9	516	35	neurological	neurological	JJ
cord-008530-yni0poh9	516	36	disease	disease	NN
cord-008530-yni0poh9	516	37	and	and	CC
cord-008530-yni0poh9	516	38	often	often	RB
cord-008530-yni0poh9	516	39	death	death	NN
cord-008530-yni0poh9	516	40	.	.	.
cord-008530-yni0poh9	517	1	In	in	IN
cord-008530-yni0poh9	517	2	the	the	DT
cord-008530-yni0poh9	517	3	viral	viral	JJ
cord-008530-yni0poh9	517	4	meningoencephalitides	meningoencephalitide	NNS
cord-008530-yni0poh9	517	5	,	,	,
cord-008530-yni0poh9	517	6	the	the	DT
cord-008530-yni0poh9	517	7	specific	specific	JJ
cord-008530-yni0poh9	517	8	mechanisms	mechanism	NNS
cord-008530-yni0poh9	517	9	underlying	underlie	VBG
cord-008530-yni0poh9	517	10	the	the	DT
cord-008530-yni0poh9	517	11	localization	localization	NN
cord-008530-yni0poh9	517	12	,	,	,
cord-008530-yni0poh9	517	13	extravasation	extravasation	NN
cord-008530-yni0poh9	517	14	,	,	,
cord-008530-yni0poh9	517	15	and	and	CC
cord-008530-yni0poh9	517	16	activation	activation	NN
cord-008530-yni0poh9	517	17	of	of	IN
cord-008530-yni0poh9	517	18	immune	immune	JJ
cord-008530-yni0poh9	517	19	cells	cell	NNS
cord-008530-yni0poh9	517	20	in	in	IN
cord-008530-yni0poh9	517	21	the	the	DT
cord-008530-yni0poh9	517	22	CNS	CNS	NNP
cord-008530-yni0poh9	517	23	and	and	CC
cord-008530-yni0poh9	517	24	the	the	DT
cord-008530-yni0poh9	517	25	subsequent	subsequent	JJ
cord-008530-yni0poh9	517	26	interactions	interaction	NNS
cord-008530-yni0poh9	517	27	between	between	IN
cord-008530-yni0poh9	517	28	these	these	DT
cord-008530-yni0poh9	517	29	cells	cell	NNS
cord-008530-yni0poh9	517	30	are	be	VBP
cord-008530-yni0poh9	517	31	not	not	RB
cord-008530-yni0poh9	517	32	well	well	RB
cord-008530-yni0poh9	517	33	understood	understand	VBN
cord-008530-yni0poh9	517	34	.	.	.
cord-008530-yni0poh9	518	1	Studies	study	NNS
cord-008530-yni0poh9	518	2	from	from	IN
cord-008530-yni0poh9	518	3	our	-PRON-	PRP$
cord-008530-yni0poh9	518	4	own	own	JJ
cord-008530-yni0poh9	518	5	laboratory	laboratory	NN
cord-008530-yni0poh9	518	6	examined	examine	VBD
cord-008530-yni0poh9	518	7	chemokine	chemokine	NN
cord-008530-yni0poh9	518	8	gene	gene	NN
cord-008530-yni0poh9	518	9	expression	expression	NN
cord-008530-yni0poh9	518	10	in	in	IN
cord-008530-yni0poh9	518	11	lymphocytic	lymphocytic	JJ
cord-008530-yni0poh9	518	12	choriomeningitis	choriomeningitis	NNP
cord-008530-yni0poh9	518	13	(	(	-LRB-
cord-008530-yni0poh9	518	14	LCM	LCM	NNP
cord-008530-yni0poh9	518	15	)	)	-RRB-
cord-008530-yni0poh9	518	16	that	that	WDT
cord-008530-yni0poh9	518	17	was	be	VBD
cord-008530-yni0poh9	518	18	induced	induce	VBN
cord-008530-yni0poh9	518	19	by	by	IN
cord-008530-yni0poh9	518	20	intracranial	intracranial	JJ
cord-008530-yni0poh9	518	21	inoculation	inoculation	NN
cord-008530-yni0poh9	518	22	of	of	IN
cord-008530-yni0poh9	518	23	mice	mouse	NNS
cord-008530-yni0poh9	518	24	with	with	IN
cord-008530-yni0poh9	518	25	LCMV	LCMV	NNP
cord-008530-yni0poh9	519	1	(	(	-LRB-
cord-008530-yni0poh9	519	2	Asensio	Asensio	NNP
cord-008530-yni0poh9	519	3	and	and	CC
cord-008530-yni0poh9	519	4	Campbell	Campbell	NNP
cord-008530-yni0poh9	519	5	,	,	,
cord-008530-yni0poh9	519	6	1997	1997	CD
cord-008530-yni0poh9	519	7	;	;	:
cord-008530-yni0poh9	519	8	Asensio	Asensio	NNP
cord-008530-yni0poh9	519	9	et	et	NNP
cord-008530-yni0poh9	519	10	al	al	NNP
cord-008530-yni0poh9	519	11	.	.	NNP
cord-008530-yni0poh9	519	12	,	,	,
cord-008530-yni0poh9	519	13	1999a	1999a	CD
cord-008530-yni0poh9	519	14	)	)	-RRB-
cord-008530-yni0poh9	519	15	.	.	.
cord-008530-yni0poh9	520	1	Following	follow	VBG
cord-008530-yni0poh9	520	2	inoculation	inoculation	NN
cord-008530-yni0poh9	520	3	,	,	,
cord-008530-yni0poh9	520	4	LCMV	LCMV	NNP
cord-008530-yni0poh9	520	5	infects	infect	VBZ
cord-008530-yni0poh9	520	6	and	and	CC
cord-008530-yni0poh9	520	7	rapidly	rapidly	RB
cord-008530-yni0poh9	520	8	replicates	replicate	VBZ
cord-008530-yni0poh9	520	9	in	in	IN
cord-008530-yni0poh9	520	10	the	the	DT
cord-008530-yni0poh9	520	11	meninges	meninge	NNS
cord-008530-yni0poh9	520	12	,	,	,
cord-008530-yni0poh9	520	13	the	the	DT
cord-008530-yni0poh9	520	14	choroid	choroid	JJ
cord-008530-yni0poh9	520	15	plexus	plexus	NN
cord-008530-yni0poh9	520	16	,	,	,
cord-008530-yni0poh9	520	17	and	and	CC
cord-008530-yni0poh9	520	18	the	the	DT
cord-008530-yni0poh9	520	19	ependymal	ependymal	JJ
cord-008530-yni0poh9	520	20	membranes	membrane	NNS
cord-008530-yni0poh9	520	21	lining	line	VBG
cord-008530-yni0poh9	520	22	the	the	DT
cord-008530-yni0poh9	520	23	ventricles	ventricle	NNS
cord-008530-yni0poh9	520	24	.	.	.
cord-008530-yni0poh9	521	1	In	in	IN
cord-008530-yni0poh9	521	2	this	this	DT
cord-008530-yni0poh9	521	3	very	very	RB
cord-008530-yni0poh9	521	4	well	well	RB
cord-008530-yni0poh9	521	5	characterized	characterize	VBN
cord-008530-yni0poh9	521	6	model	model	NN
cord-008530-yni0poh9	521	7	,	,	,
cord-008530-yni0poh9	521	8	immunocompetent	immunocompetent	JJ
cord-008530-yni0poh9	521	9	adult	adult	NN
cord-008530-yni0poh9	521	10	mice	mouse	NNS
cord-008530-yni0poh9	521	11	infected	infect	VBN
cord-008530-yni0poh9	521	12	with	with	IN
cord-008530-yni0poh9	521	13	LCMV	LCMV	NNP
cord-008530-yni0poh9	521	14	develop	develop	VB
cord-008530-yni0poh9	521	15	an	an	DT
cord-008530-yni0poh9	521	16	acute	acute	JJ
cord-008530-yni0poh9	521	17	monophasic	monophasic	JJ
cord-008530-yni0poh9	521	18	disease	disease	NN
cord-008530-yni0poh9	521	19	characterized	characterize	VBN
cord-008530-yni0poh9	521	20	by	by	IN
cord-008530-yni0poh9	521	21	the	the	DT
cord-008530-yni0poh9	521	22	presence	presence	NN
cord-008530-yni0poh9	521	23	of	of	IN
cord-008530-yni0poh9	521	24	infiltrating	infiltrate	VBG
cord-008530-yni0poh9	521	25	mononuclear	mononuclear	JJ
cord-008530-yni0poh9	521	26	cells	cell	NNS
cord-008530-yni0poh9	521	27	in	in	IN
cord-008530-yni0poh9	521	28	these	these	DT
cord-008530-yni0poh9	521	29	same	same	JJ
cord-008530-yni0poh9	521	30	regions	region	NNS
cord-008530-yni0poh9	521	31	of	of	IN
cord-008530-yni0poh9	521	32	the	the	DT
cord-008530-yni0poh9	521	33	brain	brain	NN
cord-008530-yni0poh9	521	34	,	,	,
cord-008530-yni0poh9	521	35	and	and	CC
cord-008530-yni0poh9	521	36	this	this	DT
cord-008530-yni0poh9	521	37	leads	lead	VBZ
cord-008530-yni0poh9	521	38	to	to	IN
cord-008530-yni0poh9	521	39	convulsive	convulsive	JJ
cord-008530-yni0poh9	521	40	seizures	seizure	NNS
cord-008530-yni0poh9	521	41	and	and	CC
cord-008530-yni0poh9	521	42	death	death	NN
cord-008530-yni0poh9	521	43	by	by	IN
cord-008530-yni0poh9	521	44	6	6	CD
cord-008530-yni0poh9	521	45	-	-	SYM
cord-008530-yni0poh9	521	46	8	8	CD
cord-008530-yni0poh9	521	47	days	day	NNS
cord-008530-yni0poh9	521	48	later	later	RB
cord-008530-yni0poh9	522	1	(	(	-LRB-
cord-008530-yni0poh9	522	2	Buchmeier	Buchmeier	NNP
cord-008530-yni0poh9	522	3	et	et	NNP
cord-008530-yni0poh9	522	4	al	al	NNP
cord-008530-yni0poh9	522	5	.	.	NNP
cord-008530-yni0poh9	522	6	,	,	,
cord-008530-yni0poh9	522	7	1980	1980	CD
cord-008530-yni0poh9	522	8	;	;	:
cord-008530-yni0poh9	522	9	Doherty	Doherty	NNP
cord-008530-yni0poh9	522	10	et	et	NNP
cord-008530-yni0poh9	522	11	al	al	NNP
cord-008530-yni0poh9	522	12	.	.	NNP
cord-008530-yni0poh9	522	13	,	,	,
cord-008530-yni0poh9	522	14	1990	1990	CD
cord-008530-yni0poh9	522	15	)	)	-RRB-
cord-008530-yni0poh9	522	16	.	.	.
cord-008530-yni0poh9	523	1	Infiltrating	infiltrate	VBG
cord-008530-yni0poh9	523	2	cells	cell	NNS
cord-008530-yni0poh9	523	3	are	be	VBP
cord-008530-yni0poh9	523	4	predominantly	predominantly	RB
cord-008530-yni0poh9	523	5	T	t	NN
cord-008530-yni0poh9	523	6	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	523	7	as	as	RB
cord-008530-yni0poh9	523	8	well	well	RB
cord-008530-yni0poh9	523	9	as	as	IN
cord-008530-yni0poh9	523	10	macrophages	macrophage	NNS
cord-008530-yni0poh9	523	11	.	.	.
cord-008530-yni0poh9	524	1	MHC	MHC	NNP
cord-008530-yni0poh9	524	2	class	class	NN
cord-008530-yni0poh9	524	3	-	-	HYPH
cord-008530-yni0poh9	524	4	I	i	NN
cord-008530-yni0poh9	524	5	-	-	HYPH
cord-008530-yni0poh9	524	6	restricted	restrict	VBN
cord-008530-yni0poh9	524	7	anti	anti	JJ
cord-008530-yni0poh9	524	8	-	-	JJ
cord-008530-yni0poh9	524	9	LCMV	lcmv	JJ
cord-008530-yni0poh9	524	10	CD8	CD8	NNP
cord-008530-yni0poh9	524	11	÷	÷	NNP
cord-008530-yni0poh9	524	12	cytotoxic	cytotoxic	JJ
cord-008530-yni0poh9	524	13	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	524	14	(	(	-LRB-
cord-008530-yni0poh9	524	15	CTLs	CTLs	NNP
cord-008530-yni0poh9	524	16	)	)	-RRB-
cord-008530-yni0poh9	524	17	,	,	,
cord-008530-yni0poh9	524	18	in	in	IN
cord-008530-yni0poh9	524	19	addition	addition	NN
cord-008530-yni0poh9	524	20	to	to	IN
cord-008530-yni0poh9	524	21	clearance	clearance	NN
cord-008530-yni0poh9	524	22	of	of	IN
cord-008530-yni0poh9	524	23	the	the	DT
cord-008530-yni0poh9	524	24	virus	virus	NN
cord-008530-yni0poh9	524	25	,	,	,
cord-008530-yni0poh9	524	26	are	be	VBP
cord-008530-yni0poh9	524	27	also	also	RB
cord-008530-yni0poh9	524	28	the	the	DT
cord-008530-yni0poh9	524	29	primary	primary	JJ
cord-008530-yni0poh9	524	30	effectors	effector	NNS
cord-008530-yni0poh9	524	31	of	of	IN
cord-008530-yni0poh9	524	32	LCM	LCM	NNP
cord-008530-yni0poh9	524	33	(	(	-LRB-
cord-008530-yni0poh9	524	34	Buchmeier	Buchmeier	NNP
cord-008530-yni0poh9	524	35	et	et	NNP
cord-008530-yni0poh9	524	36	al	al	NNP
cord-008530-yni0poh9	524	37	.	.	.
cord-008530-yni0poh9	525	1	,	,	,
cord-008530-yni0poh9	525	2	1980	1980	CD
cord-008530-yni0poh9	525	3	;	;	:
cord-008530-yni0poh9	525	4	Doherty	Doherty	NNP
cord-008530-yni0poh9	525	5	et	et	NNP
cord-008530-yni0poh9	525	6	al	al	NNP
cord-008530-yni0poh9	525	7	.	.	NNP
cord-008530-yni0poh9	525	8	,	,	,
cord-008530-yni0poh9	525	9	1990	1990	CD
cord-008530-yni0poh9	525	10	)	)	-RRB-
cord-008530-yni0poh9	525	11	.	.	.
cord-008530-yni0poh9	526	1	Immune	immune	NN
cord-008530-yni0poh9	526	2	-	-	HYPH
cord-008530-yni0poh9	526	3	compromised	compromise	VBN
cord-008530-yni0poh9	526	4	mice	mouse	NNS
cord-008530-yni0poh9	526	5	that	that	WDT
cord-008530-yni0poh9	526	6	are	be	VBP
cord-008530-yni0poh9	526	7	unable	unable	JJ
cord-008530-yni0poh9	526	8	,	,	,
cord-008530-yni0poh9	526	9	or	or	CC
cord-008530-yni0poh9	526	10	fail	fail	VB
cord-008530-yni0poh9	526	11	,	,	,
cord-008530-yni0poh9	526	12	to	to	TO
cord-008530-yni0poh9	526	13	mount	mount	VB
cord-008530-yni0poh9	527	1	anti	anti	JJ
cord-008530-yni0poh9	527	2	-	-	JJ
cord-008530-yni0poh9	527	3	LCMV	LCMV	NNP
cord-008530-yni0poh9	527	4	CD8	CD8	NNP
cord-008530-yni0poh9	527	5	÷	÷	NNP
cord-008530-yni0poh9	527	6	CTL	CTL	NNP
cord-008530-yni0poh9	527	7	responses	response	NNS
cord-008530-yni0poh9	527	8	do	do	VBP
cord-008530-yni0poh9	527	9	not	not	RB
cord-008530-yni0poh9	527	10	develop	develop	VB
cord-008530-yni0poh9	527	11	immune	immune	JJ
cord-008530-yni0poh9	527	12	pathology	pathology	NN
cord-008530-yni0poh9	527	13	in	in	IN
cord-008530-yni0poh9	527	14	the	the	DT
cord-008530-yni0poh9	527	15	brain	brain	NN
cord-008530-yni0poh9	527	16	and	and	CC
cord-008530-yni0poh9	527	17	survive	survive	VB
cord-008530-yni0poh9	527	18	.	.	.
cord-008530-yni0poh9	528	1	We	-PRON-	PRP
cord-008530-yni0poh9	528	2	hypothesized	hypothesize	VBD
cord-008530-yni0poh9	528	3	that	that	IN
cord-008530-yni0poh9	528	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	528	5	may	may	MD
cord-008530-yni0poh9	528	6	be	be	VB
cord-008530-yni0poh9	528	7	important	important	JJ
cord-008530-yni0poh9	528	8	regulatory	regulatory	JJ
cord-008530-yni0poh9	528	9	signals	signal	NNS
cord-008530-yni0poh9	528	10	for	for	IN
cord-008530-yni0poh9	528	11	the	the	DT
cord-008530-yni0poh9	528	12	cerebral	cerebral	JJ
cord-008530-yni0poh9	528	13	recruitment	recruitment	NNP
cord-008530-yni0poh9	528	14	and	and	CC
cord-008530-yni0poh9	528	15	extravasation	extravasation	NNP
cord-008530-yni0poh9	528	16	ofleukocytes	ofleukocytes	NNP
cord-008530-yni0poh9	528	17	in	in	IN
cord-008530-yni0poh9	528	18	LCM	LCM	NNP
cord-008530-yni0poh9	528	19	(	(	-LRB-
cord-008530-yni0poh9	528	20	Asensio	Asensio	NNP
cord-008530-yni0poh9	528	21	and	and	CC
cord-008530-yni0poh9	528	22	Campbell	Campbell	NNP
cord-008530-yni0poh9	528	23	,	,	,
cord-008530-yni0poh9	528	24	1997	1997	CD
cord-008530-yni0poh9	528	25	;	;	.
cord-008530-yni0poh9	529	1	Asensio	Asensio	NNP
cord-008530-yni0poh9	529	2	et	et	NNP
cord-008530-yni0poh9	529	3	al	al	NNP
cord-008530-yni0poh9	529	4	.	.	NNP
cord-008530-yni0poh9	529	5	,	,	,
cord-008530-yni0poh9	529	6	1999a	1999a	CD
cord-008530-yni0poh9	529	7	)	)	-RRB-
cord-008530-yni0poh9	529	8	.	.	.
cord-008530-yni0poh9	530	1	In	in	IN
cord-008530-yni0poh9	530	2	examining	examine	VBG
cord-008530-yni0poh9	530	3	this	this	DT
cord-008530-yni0poh9	530	4	,	,	,
cord-008530-yni0poh9	530	5	we	-PRON-	PRP
cord-008530-yni0poh9	530	6	observed	observe	VBD
cord-008530-yni0poh9	530	7	that	that	IN
cord-008530-yni0poh9	530	8	the	the	DT
cord-008530-yni0poh9	530	9	pattern	pattern	NN
cord-008530-yni0poh9	530	10	of	of	IN
cord-008530-yni0poh9	530	11	chemokine	chemokine	NN
cord-008530-yni0poh9	530	12	gene	gene	NN
cord-008530-yni0poh9	530	13	expression	expression	NN
cord-008530-yni0poh9	530	14	in	in	IN
cord-008530-yni0poh9	530	15	LCM	LCM	NNP
cord-008530-yni0poh9	530	16	is	be	VBZ
cord-008530-yni0poh9	530	17	dynamic	dynamic	JJ
cord-008530-yni0poh9	530	18	and	and	CC
cord-008530-yni0poh9	530	19	complex	complex	JJ
cord-008530-yni0poh9	530	20	,	,	,
cord-008530-yni0poh9	530	21	with	with	IN
cord-008530-yni0poh9	530	22	often	often	RB
cord-008530-yni0poh9	530	23	overlapping	overlapping	JJ
cord-008530-yni0poh9	530	24	expression	expression	NN
cord-008530-yni0poh9	530	25	of	of	IN
cord-008530-yni0poh9	530	26	a	a	DT
cord-008530-yni0poh9	530	27	number	number	NN
cord-008530-yni0poh9	530	28	of	of	IN
cord-008530-yni0poh9	530	29	different	different	JJ
cord-008530-yni0poh9	530	30	subclasses	subclass	NNS
cord-008530-yni0poh9	530	31	of	of	IN
cord-008530-yni0poh9	530	32	chemokine	chemokine	NN
cord-008530-yni0poh9	530	33	genes	gene	NNS
cord-008530-yni0poh9	530	34	.	.	.
cord-008530-yni0poh9	531	1	Thus	thus	RB
cord-008530-yni0poh9	531	2	,	,	,
cord-008530-yni0poh9	531	3	by	by	IN
cord-008530-yni0poh9	531	4	day	day	NN
cord-008530-yni0poh9	531	5	3	3	CD
cord-008530-yni0poh9	531	6	postinfection	postinfection	NN
cord-008530-yni0poh9	531	7	the	the	DT
cord-008530-yni0poh9	531	8	expression	expression	NN
cord-008530-yni0poh9	531	9	of	of	IN
cord-008530-yni0poh9	531	10	a	a	DT
cord-008530-yni0poh9	531	11	number	number	NN
cord-008530-yni0poh9	531	12	of	of	IN
cord-008530-yni0poh9	531	13	chemokine	chemokine	NN
cord-008530-yni0poh9	531	14	genes	gene	NNS
cord-008530-yni0poh9	531	15	is	be	VBZ
cord-008530-yni0poh9	531	16	evident	evident	JJ
cord-008530-yni0poh9	531	17	,	,	,
cord-008530-yni0poh9	531	18	including	include	VBG
cord-008530-yni0poh9	531	19	C10	C10	NNP
cord-008530-yni0poh9	531	20	,	,	,
cord-008530-yni0poh9	531	21	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	531	22	,	,	,
cord-008530-yni0poh9	531	23	MIP	MIP	NNP
cord-008530-yni0poh9	531	24	-	-	HYPH
cord-008530-yni0poh9	531	25	I~	I~	NNP
cord-008530-yni0poh9	531	26	,	,	,
cord-008530-yni0poh9	531	27	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	531	28	,	,	,
cord-008530-yni0poh9	531	29	CRG-2	CRG-2	NNP
cord-008530-yni0poh9	531	30	/	/	SYM
cord-008530-yni0poh9	531	31	IP-10	IP-10	NNP
cord-008530-yni0poh9	531	32	,	,	,
cord-008530-yni0poh9	531	33	and	and	CC
cord-008530-yni0poh9	531	34	RANTES	RANTES	NNP
cord-008530-yni0poh9	531	35	.	.	.
cord-008530-yni0poh9	532	1	By	by	IN
cord-008530-yni0poh9	532	2	day	day	NN
cord-008530-yni0poh9	532	3	6	6	CD
cord-008530-yni0poh9	532	4	postinfection	postinfection	NN
cord-008530-yni0poh9	533	1	the	the	DT
cord-008530-yni0poh9	533	2	expression	expression	NN
cord-008530-yni0poh9	533	3	of	of	IN
cord-008530-yni0poh9	533	4	all	all	PDT
cord-008530-yni0poh9	533	5	these	these	DT
cord-008530-yni0poh9	533	6	chemokine	chemokine	NN
cord-008530-yni0poh9	533	7	genes	gene	NNS
cord-008530-yni0poh9	533	8	increases	increase	VBZ
cord-008530-yni0poh9	533	9	markedly	markedly	RB
cord-008530-yni0poh9	533	10	and	and	CC
cord-008530-yni0poh9	533	11	the	the	DT
cord-008530-yni0poh9	533	12	expression	expression	NN
cord-008530-yni0poh9	533	13	of	of	IN
cord-008530-yni0poh9	533	14	the	the	DT
cord-008530-yni0poh9	533	15	lymphotactin	lymphotactin	NNP
cord-008530-yni0poh9	533	16	gene	gene	NN
cord-008530-yni0poh9	533	17	is	be	VBZ
cord-008530-yni0poh9	533	18	also	also	RB
cord-008530-yni0poh9	533	19	evident	evident	JJ
cord-008530-yni0poh9	533	20	in	in	IN
cord-008530-yni0poh9	533	21	the	the	DT
cord-008530-yni0poh9	533	22	brain	brain	NN
cord-008530-yni0poh9	533	23	.	.	.
cord-008530-yni0poh9	534	1	A	a	DT
cord-008530-yni0poh9	534	2	qualitatively	qualitatively	RB
cord-008530-yni0poh9	534	3	similar	similar	JJ
cord-008530-yni0poh9	534	4	but	but	CC
cord-008530-yni0poh9	534	5	markedly	markedly	RB
cord-008530-yni0poh9	534	6	decreased	decrease	VBD
cord-008530-yni0poh9	534	7	level	level	NN
cord-008530-yni0poh9	534	8	of	of	IN
cord-008530-yni0poh9	534	9	chemokine	chemokine	NN
cord-008530-yni0poh9	534	10	gene	gene	NN
cord-008530-yni0poh9	534	11	expression	expression	NN
cord-008530-yni0poh9	534	12	is	be	VBZ
cord-008530-yni0poh9	534	13	observed	observe	VBN
cord-008530-yni0poh9	534	14	in	in	IN
cord-008530-yni0poh9	534	15	the	the	DT
cord-008530-yni0poh9	534	16	brain	brain	NN
cord-008530-yni0poh9	534	17	of	of	IN
cord-008530-yni0poh9	534	18	LCMV	LCMV	NNP
cord-008530-yni0poh9	534	19	-	-	HYPH
cord-008530-yni0poh9	534	20	infected	infect	VBN
cord-008530-yni0poh9	534	21	athymic	athymic	JJ
cord-008530-yni0poh9	534	22	mice	mouse	NNS
cord-008530-yni0poh9	534	23	.	.	.
cord-008530-yni0poh9	535	1	A	a	DT
cord-008530-yni0poh9	535	2	similar	similar	JJ
cord-008530-yni0poh9	535	3	pattern	pattern	NN
cord-008530-yni0poh9	535	4	of	of	IN
cord-008530-yni0poh9	535	5	cerebral	cerebral	JJ
cord-008530-yni0poh9	535	6	chemokine	chemokine	NN
cord-008530-yni0poh9	535	7	gene	gene	NN
cord-008530-yni0poh9	535	8	expression	expression	NN
cord-008530-yni0poh9	535	9	is	be	VBZ
cord-008530-yni0poh9	535	10	also	also	RB
cord-008530-yni0poh9	535	11	found	find	VBN
cord-008530-yni0poh9	535	12	in	in	IN
cord-008530-yni0poh9	535	13	LCMV	LCMV	NNP
cord-008530-yni0poh9	535	14	-	-	HYPH
cord-008530-yni0poh9	535	15	infected	infect	VBN
cord-008530-yni0poh9	535	16	IFN	IFN	NNP
cord-008530-yni0poh9	535	17	-	-	HYPH
cord-008530-yni0poh9	535	18	y	y	NNP
cord-008530-yni0poh9	535	19	KO	KO	NNP
cord-008530-yni0poh9	535	20	mice	mouse	NNS
cord-008530-yni0poh9	535	21	,	,	,
cord-008530-yni0poh9	535	22	although	although	IN
cord-008530-yni0poh9	535	23	the	the	DT
cord-008530-yni0poh9	535	24	levels	level	NNS
cord-008530-yni0poh9	535	25	of	of	IN
cord-008530-yni0poh9	535	26	expression	expression	NN
cord-008530-yni0poh9	535	27	in	in	IN
cord-008530-yni0poh9	535	28	the	the	DT
cord-008530-yni0poh9	535	29	absence	absence	NN
cord-008530-yni0poh9	535	30	of	of	IN
cord-008530-yni0poh9	535	31	IFN	IFN	NNP
cord-008530-yni0poh9	535	32	-	-	HYPH
cord-008530-yni0poh9	535	33	y	y	NNP
cord-008530-yni0poh9	535	34	are	be	VBP
cord-008530-yni0poh9	535	35	about	about	RB
cord-008530-yni0poh9	535	36	50	50	CD
cord-008530-yni0poh9	535	37	%	%	NN
cord-008530-yni0poh9	535	38	of	of	IN
cord-008530-yni0poh9	535	39	those	those	DT
cord-008530-yni0poh9	535	40	in	in	IN
cord-008530-yni0poh9	535	41	LCMV	LCMV	NNP
cord-008530-yni0poh9	535	42	-	-	HYPH
cord-008530-yni0poh9	535	43	infected	infect	VBN
cord-008530-yni0poh9	535	44	wild	wild	JJ
cord-008530-yni0poh9	535	45	-	-	HYPH
cord-008530-yni0poh9	535	46	type	type	NN
cord-008530-yni0poh9	535	47	controls	control	NNS
cord-008530-yni0poh9	535	48	.	.	.
cord-008530-yni0poh9	536	1	In	in	IN
cord-008530-yni0poh9	536	2	both	both	CC
cord-008530-yni0poh9	536	3	euthymic	euthymic	JJ
cord-008530-yni0poh9	536	4	and	and	CC
cord-008530-yni0poh9	536	5	athymic	athymic	JJ
cord-008530-yni0poh9	536	6	mice	mouse	NNS
cord-008530-yni0poh9	536	7	,	,	,
cord-008530-yni0poh9	536	8	expression	expression	NN
cord-008530-yni0poh9	536	9	of	of	IN
cord-008530-yni0poh9	536	10	IP-10	IP-10	NNP
cord-008530-yni0poh9	536	11	was	be	VBD
cord-008530-yni0poh9	536	12	predominant	predominant	JJ
cord-008530-yni0poh9	536	13	at	at	IN
cord-008530-yni0poh9	536	14	both	both	CC
cord-008530-yni0poh9	536	15	early	early	JJ
cord-008530-yni0poh9	536	16	and	and	CC
cord-008530-yni0poh9	536	17	late	late	JJ
cord-008530-yni0poh9	536	18	time	time	NN
cord-008530-yni0poh9	536	19	points	point	NNS
cord-008530-yni0poh9	536	20	after	after	IN
cord-008530-yni0poh9	536	21	infection	infection	NN
cord-008530-yni0poh9	536	22	and	and	CC
cord-008530-yni0poh9	536	23	preceded	precede	VBD
cord-008530-yni0poh9	536	24	detectable	detectable	JJ
cord-008530-yni0poh9	536	25	increases	increase	NNS
cord-008530-yni0poh9	536	26	in	in	IN
cord-008530-yni0poh9	536	27	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	536	28	and	and	CC
cord-008530-yni0poh9	536	29	interferon	interferon	NN
cord-008530-yni0poh9	536	30	cytokine	cytokine	NN
cord-008530-yni0poh9	536	31	gene	gene	NN
cord-008530-yni0poh9	536	32	expression	expression	NN
cord-008530-yni0poh9	536	33	and	and	CC
cord-008530-yni0poh9	536	34	CNS	CNS	NNP
cord-008530-yni0poh9	536	35	leukocyte	leukocyte	NN
cord-008530-yni0poh9	536	36	recruitment	recruitment	NN
cord-008530-yni0poh9	536	37	in	in	IN
cord-008530-yni0poh9	536	38	euthymic	euthymic	JJ
cord-008530-yni0poh9	536	39	mice	mouse	NNS
cord-008530-yni0poh9	536	40	.	.	.
cord-008530-yni0poh9	537	1	In	in	IN
cord-008530-yni0poh9	537	2	all	all	DT
cord-008530-yni0poh9	537	3	,	,	,
cord-008530-yni0poh9	537	4	FIG	FIG	NNP
cord-008530-yni0poh9	537	5	2	2	CD
cord-008530-yni0poh9	537	6	.	.	.
cord-008530-yni0poh9	538	1	The	the	DT
cord-008530-yni0poh9	538	2	CXC	CXC	NNP
cord-008530-yni0poh9	538	3	chemokine	chemokine	NN
cord-008530-yni0poh9	538	4	IP-10	IP-10	NNP
cord-008530-yni0poh9	538	5	is	be	VBZ
cord-008530-yni0poh9	538	6	expressed	express	VBN
cord-008530-yni0poh9	538	7	at	at	IN
cord-008530-yni0poh9	538	8	high	high	JJ
cord-008530-yni0poh9	538	9	levels	level	NNS
cord-008530-yni0poh9	538	10	in	in	IN
cord-008530-yni0poh9	538	11	the	the	DT
cord-008530-yni0poh9	538	12	brain	brain	NN
cord-008530-yni0poh9	538	13	,	,	,
cord-008530-yni0poh9	538	14	following	follow	VBG
cord-008530-yni0poh9	538	15	infection	infection	NN
cord-008530-yni0poh9	538	16	by	by	IN
cord-008530-yni0poh9	538	17	many	many	JJ
cord-008530-yni0poh9	538	18	viruses	virus	NNS
cord-008530-yni0poh9	538	19	.	.	.
cord-008530-yni0poh9	539	1	In	in	IN
cord-008530-yni0poh9	539	2	this	this	DT
cord-008530-yni0poh9	539	3	example	example	NN
cord-008530-yni0poh9	539	4	mice	mouse	NNS
cord-008530-yni0poh9	539	5	were	be	VBD
cord-008530-yni0poh9	539	6	infected	infect	VBN
cord-008530-yni0poh9	539	7	intracranially	intracranially	RB
cord-008530-yni0poh9	539	8	with	with	IN
cord-008530-yni0poh9	539	9	LCMV	LCMV	NNP
cord-008530-yni0poh9	539	10	,	,	,
cord-008530-yni0poh9	539	11	and	and	CC
cord-008530-yni0poh9	539	12	the	the	DT
cord-008530-yni0poh9	539	13	viral	viral	JJ
cord-008530-yni0poh9	539	14	nucleoprotein	nucleoprotein	NNP
cord-008530-yni0poh9	539	15	(	(	-LRB-
cord-008530-yni0poh9	539	16	NP	NP	NNP
cord-008530-yni0poh9	539	17	)	)	-RRB-
cord-008530-yni0poh9	539	18	and	and	CC
cord-008530-yni0poh9	539	19	IP-10	IP-10	NNP
cord-008530-yni0poh9	539	20	RNA	RNA	NNP
cord-008530-yni0poh9	539	21	expression	expression	NN
cord-008530-yni0poh9	539	22	in	in	IN
cord-008530-yni0poh9	539	23	the	the	DT
cord-008530-yni0poh9	539	24	brain	brain	NN
cord-008530-yni0poh9	539	25	were	be	VBD
cord-008530-yni0poh9	539	26	analyzed	analyze	VBN
cord-008530-yni0poh9	539	27	by	by	IN
cord-008530-yni0poh9	539	28	in	in	IN
cord-008530-yni0poh9	539	29	situ	situ	NN
cord-008530-yni0poh9	539	30	hybridization	hybridization	NN
cord-008530-yni0poh9	539	31	.	.	.
cord-008530-yni0poh9	540	1	High	high	JJ
cord-008530-yni0poh9	540	2	expression	expression	NN
cord-008530-yni0poh9	540	3	of	of	IN
cord-008530-yni0poh9	540	4	IP-10	IP-10	NNP
cord-008530-yni0poh9	540	5	RNA	RNA	NNP
cord-008530-yni0poh9	540	6	was	be	VBD
cord-008530-yni0poh9	540	7	apparent	apparent	JJ
cord-008530-yni0poh9	540	8	by	by	IN
cord-008530-yni0poh9	540	9	day	day	NN
cord-008530-yni0poh9	540	10	3	3	CD
cord-008530-yni0poh9	541	1	(	(	-LRB-
cord-008530-yni0poh9	541	2	A	a	NN
cord-008530-yni0poh9	541	3	)	)	-RRB-
cord-008530-yni0poh9	541	4	postinfection	postinfection	NN
cord-008530-yni0poh9	541	5	and	and	CC
cord-008530-yni0poh9	541	6	increased	increase	VBN
cord-008530-yni0poh9	541	7	further	further	RB
cord-008530-yni0poh9	541	8	by	by	IN
cord-008530-yni0poh9	541	9	day	day	NN
cord-008530-yni0poh9	541	10	6	6	CD
cord-008530-yni0poh9	541	11	(	(	-LRB-
cord-008530-yni0poh9	541	12	B	b	NN
cord-008530-yni0poh9	541	13	)	)	-RRB-
cord-008530-yni0poh9	541	14	postinfection	postinfection	NN
cord-008530-yni0poh9	541	15	.	.	.
cord-008530-yni0poh9	542	1	Regional	regional	JJ
cord-008530-yni0poh9	542	2	expression	expression	NN
cord-008530-yni0poh9	542	3	of	of	IN
cord-008530-yni0poh9	542	4	IP-10	IP-10	NNP
cord-008530-yni0poh9	542	5	RNA	RNA	NNP
cord-008530-yni0poh9	542	6	,	,	,
cord-008530-yni0poh9	542	7	on	on	IN
cord-008530-yni0poh9	542	8	the	the	DT
cord-008530-yni0poh9	542	9	whole	whole	NN
cord-008530-yni0poh9	542	10	,	,	,
cord-008530-yni0poh9	542	11	overlapped	overlap	VBN
cord-008530-yni0poh9	542	12	with	with	IN
cord-008530-yni0poh9	542	13	sites	site	NNS
cord-008530-yni0poh9	542	14	of	of	IN
cord-008530-yni0poh9	542	15	viral	viral	JJ
cord-008530-yni0poh9	542	16	infection	infection	NN
cord-008530-yni0poh9	542	17	,	,	,
cord-008530-yni0poh9	542	18	as	as	IN
cord-008530-yni0poh9	542	19	indicated	indicate	VBN
cord-008530-yni0poh9	542	20	by	by	IN
cord-008530-yni0poh9	542	21	the	the	DT
cord-008530-yni0poh9	542	22	expression	expression	NN
cord-008530-yni0poh9	542	23	of	of	IN
cord-008530-yni0poh9	542	24	the	the	DT
cord-008530-yni0poh9	542	25	LCMV	LCMV	NNP
cord-008530-yni0poh9	542	26	-	-	HYPH
cord-008530-yni0poh9	542	27	NP	NP	NNP
cord-008530-yni0poh9	542	28	gene	gene	NN
cord-008530-yni0poh9	542	29	.	.	.
cord-008530-yni0poh9	543	1	However	however	RB
cord-008530-yni0poh9	543	2	,	,	,
cord-008530-yni0poh9	543	3	parenchymal	parenchymal	JJ
cord-008530-yni0poh9	543	4	expression	expression	NN
cord-008530-yni0poh9	543	5	of	of	IN
cord-008530-yni0poh9	543	6	the	the	DT
cord-008530-yni0poh9	543	7	IP-10	IP-10	NNP
cord-008530-yni0poh9	543	8	gene	gene	NN
cord-008530-yni0poh9	543	9	was	be	VBD
cord-008530-yni0poh9	543	10	also	also	RB
cord-008530-yni0poh9	543	11	found	find	VBN
cord-008530-yni0poh9	543	12	in	in	IN
cord-008530-yni0poh9	543	13	the	the	DT
cord-008530-yni0poh9	543	14	absence	absence	NN
cord-008530-yni0poh9	543	15	of	of	IN
cord-008530-yni0poh9	543	16	local	local	JJ
cord-008530-yni0poh9	543	17	LCMV	LCMV	NNP
cord-008530-yni0poh9	543	18	-	-	HYPH
cord-008530-yni0poh9	543	19	NP	NP	NNP
cord-008530-yni0poh9	543	20	expression	expression	NN
cord-008530-yni0poh9	543	21	.	.	.
cord-008530-yni0poh9	544	1	By	by	IN
cord-008530-yni0poh9	544	2	using	use	VBG
cord-008530-yni0poh9	544	3	dual	dual	JJ
cord-008530-yni0poh9	544	4	-	-	HYPH
cord-008530-yni0poh9	544	5	label	label	NN
cord-008530-yni0poh9	544	6	analysis	analysis	NN
cord-008530-yni0poh9	544	7	to	to	TO
cord-008530-yni0poh9	544	8	identify	identify	VB
cord-008530-yni0poh9	544	9	the	the	DT
cord-008530-yni0poh9	544	10	cellular	cellular	JJ
cord-008530-yni0poh9	544	11	localization	localization	NN
cord-008530-yni0poh9	544	12	of	of	IN
cord-008530-yni0poh9	544	13	IP-10	IP-10	NNP
cord-008530-yni0poh9	544	14	RNA	RNA	NNP
cord-008530-yni0poh9	544	15	expression	expression	NN
cord-008530-yni0poh9	544	16	,	,	,
cord-008530-yni0poh9	544	17	these	these	DT
cord-008530-yni0poh9	544	18	parenchymal	parenchymal	NN
cord-008530-yni0poh9	544	19	cells	cell	NNS
cord-008530-yni0poh9	544	20	were	be	VBD
cord-008530-yni0poh9	544	21	identified	identify	VBN
cord-008530-yni0poh9	544	22	as	as	IN
cord-008530-yni0poh9	544	23	GFAP	GFAP	NNP
cord-008530-yni0poh9	544	24	-	-	HYPH
cord-008530-yni0poh9	544	25	positive	positive	JJ
cord-008530-yni0poh9	544	26	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	544	27	(	(	-LRB-
cord-008530-yni0poh9	544	28	C	c	NN
cord-008530-yni0poh9	544	29	;	;	:
cord-008530-yni0poh9	544	30	arrows	arrow	NNS
cord-008530-yni0poh9	544	31	)	)	-RRB-
cord-008530-yni0poh9	544	32	.	.	.
cord-008530-yni0poh9	545	1	From	from	IN
cord-008530-yni0poh9	545	2	Asensio	Asensio	NNP
cord-008530-yni0poh9	545	3	,	,	,
cord-008530-yni0poh9	545	4	V.	V.	NNP
cord-008530-yni0poh9	545	5	C.	C.	NNP
cord-008530-yni0poh9	545	6	,	,	,
cord-008530-yni0poh9	545	7	Kincaid	Kincaid	NNP
cord-008530-yni0poh9	545	8	,	,	,
cord-008530-yni0poh9	545	9	C.	C.	NNP
cord-008530-yni0poh9	545	10	,	,	,
cord-008530-yni0poh9	545	11	and	and	CC
cord-008530-yni0poh9	545	12	Campbell	Campbell	NNP
cord-008530-yni0poh9	545	13	,	,	,
cord-008530-yni0poh9	545	14	I.	I.	NNP
cord-008530-yni0poh9	545	15	L.	L.	NNP
cord-008530-yni0poh9	545	16	Chemokines	Chemokines	NNP
cord-008530-yni0poh9	545	17	and	and	CC
cord-008530-yni0poh9	545	18	the	the	DT
cord-008530-yni0poh9	545	19	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	545	20	response	response	NN
cord-008530-yni0poh9	545	21	to	to	IN
cord-008530-yni0poh9	545	22	viral	viral	JJ
cord-008530-yni0poh9	545	23	infection	infection	NN
cord-008530-yni0poh9	545	24	in	in	IN
cord-008530-yni0poh9	545	25	the	the	DT
cord-008530-yni0poh9	545	26	156	156	CD
cord-008530-yni0poh9	545	27	VALl	VALl	NNS
cord-008530-yni0poh9	545	28	~	~	NFP
cord-008530-yni0poh9	545	29	RIE	RIE	NNP
cord-008530-yni0poh9	545	30	C.	C.	NNP
cord-008530-yni0poh9	545	31	ASENSIO	ASENSIO	NNP
cord-008530-yni0poh9	545	32	AND	and	CC
cord-008530-yni0poh9	545	33	IAIN	IAIN	NNP
cord-008530-yni0poh9	545	34	L.	L.	NNP
cord-008530-yni0poh9	545	35	CAMPBELL	CAMPBELL	NNP
cord-008530-yni0poh9	545	36	these	these	DT
cord-008530-yni0poh9	545	37	observations	observation	NNS
cord-008530-yni0poh9	545	38	,	,	,
cord-008530-yni0poh9	545	39	together	together	RB
cord-008530-yni0poh9	545	40	with	with	IN
cord-008530-yni0poh9	545	41	the	the	DT
cord-008530-yni0poh9	545	42	finding	finding	NN
cord-008530-yni0poh9	545	43	that	that	IN
cord-008530-yni0poh9	545	44	CRG-2	CRG-2	NNP
cord-008530-yni0poh9	545	45	/	/	SYM
cord-008530-yni0poh9	545	46	IP-10	IP-10	NNP
cord-008530-yni0poh9	545	47	,	,	,
cord-008530-yni0poh9	545	48	a	a	DT
cord-008530-yni0poh9	545	49	prominently	prominently	RB
cord-008530-yni0poh9	545	50	expressed	express	VBN
cord-008530-yni0poh9	545	51	chemokine	chemokine	NN
cord-008530-yni0poh9	545	52	gene	gene	NN
cord-008530-yni0poh9	545	53	in	in	IN
cord-008530-yni0poh9	545	54	many	many	JJ
cord-008530-yni0poh9	545	55	different	different	JJ
cord-008530-yni0poh9	545	56	CNS	CNS	NNP
cord-008530-yni0poh9	545	57	viral	viral	JJ
cord-008530-yni0poh9	545	58	infections	infection	NNS
cord-008530-yni0poh9	545	59	,	,	,
cord-008530-yni0poh9	545	60	is	be	VBZ
cord-008530-yni0poh9	545	61	expressed	express	VBN
cord-008530-yni0poh9	545	62	by	by	IN
cord-008530-yni0poh9	545	63	resident	resident	JJ
cord-008530-yni0poh9	545	64	CNS	CNS	NNP
cord-008530-yni0poh9	545	65	cells	cell	NNS
cord-008530-yni0poh9	545	66	including	include	VBG
cord-008530-yni0poh9	545	67	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	545	68	(	(	-LRB-
cord-008530-yni0poh9	545	69	see	see	VB
cord-008530-yni0poh9	545	70	Fig	Fig	NNP
cord-008530-yni0poh9	545	71	.	.	NNP
cord-008530-yni0poh9	545	72	2	2	CD
cord-008530-yni0poh9	545	73	)	)	-RRB-
cord-008530-yni0poh9	545	74	,	,	,
cord-008530-yni0poh9	545	75	suggest	suggest	VBP
cord-008530-yni0poh9	545	76	that	that	IN
cord-008530-yni0poh9	545	77	activation	activation	NN
cord-008530-yni0poh9	545	78	ofchemokine	ofchemokine	NN
cord-008530-yni0poh9	545	79	gene	gene	NN
cord-008530-yni0poh9	545	80	expression	expression	NN
cord-008530-yni0poh9	545	81	may	may	MD
cord-008530-yni0poh9	545	82	be	be	VB
cord-008530-yni0poh9	545	83	a	a	DT
cord-008530-yni0poh9	545	84	direct	direct	JJ
cord-008530-yni0poh9	545	85	,	,	,
cord-008530-yni0poh9	545	86	early	early	JJ
cord-008530-yni0poh9	545	87	,	,	,
cord-008530-yni0poh9	545	88	and	and	CC
cord-008530-yni0poh9	545	89	localized	localize	VBD
cord-008530-yni0poh9	545	90	host	host	NN
cord-008530-yni0poh9	545	91	response	response	NN
cord-008530-yni0poh9	545	92	to	to	IN
cord-008530-yni0poh9	545	93	LCMV	LCMV	NNP
cord-008530-yni0poh9	545	94	infection	infection	NN
cord-008530-yni0poh9	545	95	.	.	.
cord-008530-yni0poh9	546	1	These	these	DT
cord-008530-yni0poh9	546	2	findings	finding	NNS
cord-008530-yni0poh9	546	3	are	be	VBP
cord-008530-yni0poh9	546	4	consistent	consistent	JJ
cord-008530-yni0poh9	546	5	with	with	IN
cord-008530-yni0poh9	546	6	the	the	DT
cord-008530-yni0poh9	546	7	proposed	propose	VBN
cord-008530-yni0poh9	546	8	involvement	involvement	NN
cord-008530-yni0poh9	546	9	of	of	IN
cord-008530-yni0poh9	546	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	546	11	as	as	IN
cord-008530-yni0poh9	546	12	key	key	JJ
cord-008530-yni0poh9	546	13	signaling	signal	VBG
cord-008530-yni0poh9	546	14	molecules	molecule	NNS
cord-008530-yni0poh9	546	15	for	for	IN
cord-008530-yni0poh9	546	16	the	the	DT
cord-008530-yni0poh9	546	17	subsequent	subsequent	JJ
cord-008530-yni0poh9	546	18	migration	migration	NN
cord-008530-yni0poh9	546	19	of	of	IN
cord-008530-yni0poh9	546	20	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	546	21	to	to	IN
cord-008530-yni0poh9	546	22	the	the	DT
cord-008530-yni0poh9	546	23	CNS	CNS	NNP
cord-008530-yni0poh9	546	24	,	,	,
cord-008530-yni0poh9	546	25	following	follow	VBG
cord-008530-yni0poh9	546	26	LCMV	LCMV	NNP
cord-008530-yni0poh9	546	27	infection	infection	NN
cord-008530-yni0poh9	546	28	.	.	.
cord-008530-yni0poh9	547	1	However	however	RB
cord-008530-yni0poh9	547	2	,	,	,
cord-008530-yni0poh9	547	3	formal	formal	JJ
cord-008530-yni0poh9	547	4	demonstration	demonstration	NN
cord-008530-yni0poh9	547	5	of	of	IN
cord-008530-yni0poh9	547	6	the	the	DT
cord-008530-yni0poh9	547	7	precise	precise	JJ
cord-008530-yni0poh9	547	8	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	547	9	,	,	,
cord-008530-yni0poh9	547	10	and	and	CC
cord-008530-yni0poh9	547	11	possibly	possibly	RB
cord-008530-yni0poh9	547	12	of	of	IN
cord-008530-yni0poh9	547	13	other	other	JJ
cord-008530-yni0poh9	547	14	functions	function	NNS
cord-008530-yni0poh9	547	15	of	of	IN
cord-008530-yni0poh9	547	16	chemokines	chemokine	NNS
cord-008530-yni0poh9	547	17	in	in	IN
cord-008530-yni0poh9	547	18	LCM	LCM	NNP
cord-008530-yni0poh9	547	19	,	,	,
cord-008530-yni0poh9	547	20	presently	presently	RB
cord-008530-yni0poh9	547	21	awaits	await	VBZ
cord-008530-yni0poh9	547	22	verification	verification	NN
cord-008530-yni0poh9	547	23	.	.	.
cord-008530-yni0poh9	548	1	Herpes	Herpes	NNP
cord-008530-yni0poh9	548	2	simplex	simplex	NN
cord-008530-yni0poh9	548	3	virus	virus	NN
cord-008530-yni0poh9	548	4	(	(	-LRB-
cord-008530-yni0poh9	548	5	HSV	HSV	NNP
cord-008530-yni0poh9	548	6	)	)	-RRB-
cord-008530-yni0poh9	548	7	is	be	VBZ
cord-008530-yni0poh9	548	8	a	a	DT
cord-008530-yni0poh9	548	9	common	common	JJ
cord-008530-yni0poh9	548	10	etiologic	etiologic	JJ
cord-008530-yni0poh9	548	11	agent	agent	NN
cord-008530-yni0poh9	548	12	of	of	IN
cord-008530-yni0poh9	548	13	acute	acute	JJ
cord-008530-yni0poh9	548	14	focal	focal	JJ
cord-008530-yni0poh9	548	15	encephalitis	encephalitis	RB
cord-008530-yni0poh9	548	16	.	.	.
cord-008530-yni0poh9	549	1	Pathologically	pathologically	RB
cord-008530-yni0poh9	549	2	,	,	,
cord-008530-yni0poh9	549	3	in	in	IN
cord-008530-yni0poh9	549	4	HSV	HSV	NNP
cord-008530-yni0poh9	549	5	encephalitis	encephalitis	RB
cord-008530-yni0poh9	549	6	,	,	,
cord-008530-yni0poh9	549	7	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	549	8	infiltrate	infiltrate	VBP
cord-008530-yni0poh9	549	9	the	the	DT
cord-008530-yni0poh9	549	10	subarachnoid	subarachnoid	NN
cord-008530-yni0poh9	549	11	space	space	NN
cord-008530-yni0poh9	549	12	as	as	IN
cord-008530-yni0poh9	549	13	a	a	DT
cord-008530-yni0poh9	549	14	hallmark	hallmark	NN
cord-008530-yni0poh9	549	15	of	of	IN
cord-008530-yni0poh9	549	16	meningitis	meningitis	NN
cord-008530-yni0poh9	549	17	and	and	CC
cord-008530-yni0poh9	549	18	encephalitis	encephalitis	RB
cord-008530-yni0poh9	549	19	,	,	,
cord-008530-yni0poh9	549	20	while	while	IN
cord-008530-yni0poh9	549	21	CSF	CSF	NNP
cord-008530-yni0poh9	549	22	analysis	analysis	NN
cord-008530-yni0poh9	549	23	typically	typically	RB
cord-008530-yni0poh9	549	24	reveals	reveal	VBZ
cord-008530-yni0poh9	549	25	a	a	DT
cord-008530-yni0poh9	549	26	predominantly	predominantly	RB
cord-008530-yni0poh9	549	27	lymphocytic	lymphocytic	JJ
cord-008530-yni0poh9	549	28	pleocytosis	pleocytosis	NN
cord-008530-yni0poh9	549	29	.	.	.
cord-008530-yni0poh9	550	1	To	to	TO
cord-008530-yni0poh9	550	2	evaluate	evaluate	VB
cord-008530-yni0poh9	550	3	the	the	DT
cord-008530-yni0poh9	550	4	possible	possible	JJ
cord-008530-yni0poh9	550	5	contribution	contribution	NN
cord-008530-yni0poh9	550	6	of	of	IN
cord-008530-yni0poh9	550	7	chemokines	chemokine	NNS
cord-008530-yni0poh9	550	8	to	to	IN
cord-008530-yni0poh9	550	9	HSV	HSV	NNP
cord-008530-yni0poh9	550	10	encephalitis	encephalitis	RB
cord-008530-yni0poh9	550	11	,	,	,
cord-008530-yni0poh9	550	12	Rosler	Rosler	NNP
cord-008530-yni0poh9	550	13	and	and	CC
cord-008530-yni0poh9	550	14	coworkers	coworker	NNS
cord-008530-yni0poh9	550	15	examined	examine	VBD
cord-008530-yni0poh9	550	16	the	the	DT
cord-008530-yni0poh9	550	17	spectrum	spectrum	NN
cord-008530-yni0poh9	550	18	,	,	,
cord-008530-yni0poh9	550	19	quantity	quantity	NN
cord-008530-yni0poh9	550	20	,	,	,
cord-008530-yni0poh9	550	21	and	and	CC
cord-008530-yni0poh9	550	22	time	time	NN
cord-008530-yni0poh9	550	23	course	course	NN
cord-008530-yni0poh9	550	24	of	of	IN
cord-008530-yni0poh9	550	25	CSF	CSF	NNP
cord-008530-yni0poh9	550	26	chemokines	chemokine	NNS
cord-008530-yni0poh9	550	27	in	in	IN
cord-008530-yni0poh9	550	28	three	three	CD
cord-008530-yni0poh9	550	29	patients	patient	NNS
cord-008530-yni0poh9	550	30	with	with	IN
cord-008530-yni0poh9	550	31	proven	prove	VBN
cord-008530-yni0poh9	550	32	HSV	HSV	NNP
cord-008530-yni0poh9	550	33	type	type	NN
cord-008530-yni0poh9	550	34	1	1	CD
cord-008530-yni0poh9	550	35	encephalitis	encephalitis	NN
cord-008530-yni0poh9	550	36	(	(	-LRB-
cord-008530-yni0poh9	550	37	HSE-1	HSE-1	NNP
cord-008530-yni0poh9	550	38	)	)	-RRB-
cord-008530-yni0poh9	551	1	(	(	-LRB-
cord-008530-yni0poh9	551	2	Rosler	Rosler	NNP
cord-008530-yni0poh9	551	3	et	et	NNP
cord-008530-yni0poh9	551	4	al	al	NNP
cord-008530-yni0poh9	551	5	.	.	NNP
cord-008530-yni0poh9	551	6	,	,	,
cord-008530-yni0poh9	551	7	1998	1998	CD
cord-008530-yni0poh9	551	8	)	)	-RRB-
cord-008530-yni0poh9	551	9	.	.	.
cord-008530-yni0poh9	552	1	High	high	JJ
cord-008530-yni0poh9	552	2	chemokine	chemokine	NN
cord-008530-yni0poh9	552	3	levels	level	NNS
cord-008530-yni0poh9	552	4	were	be	VBD
cord-008530-yni0poh9	552	5	present	present	JJ
cord-008530-yni0poh9	552	6	in	in	IN
cord-008530-yni0poh9	552	7	the	the	DT
cord-008530-yni0poh9	552	8	CSF	CSF	NNP
cord-008530-yni0poh9	552	9	of	of	IN
cord-008530-yni0poh9	552	10	all	all	DT
cord-008530-yni0poh9	552	11	HSE-1	HSE-1	NNP
cord-008530-yni0poh9	552	12	patients	patient	NNS
cord-008530-yni0poh9	552	13	.	.	.
cord-008530-yni0poh9	553	1	Peak	peak	NN
cord-008530-yni0poh9	553	2	levels	level	NNS
cord-008530-yni0poh9	553	3	occurred	occur	VBD
cord-008530-yni0poh9	553	4	at	at	IN
cord-008530-yni0poh9	553	5	the	the	DT
cord-008530-yni0poh9	553	6	time	time	NN
cord-008530-yni0poh9	553	7	of	of	IN
cord-008530-yni0poh9	553	8	admission	admission	NN
cord-008530-yni0poh9	553	9	,	,	,
cord-008530-yni0poh9	553	10	with	with	IN
cord-008530-yni0poh9	553	11	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	553	12	being	be	VBG
cord-008530-yni0poh9	553	13	greater	great	JJR
cord-008530-yni0poh9	553	14	than	than	IN
cord-008530-yni0poh9	553	15	either	either	DT
cord-008530-yni0poh9	553	16	MIP	MIP	NNP
cord-008530-yni0poh9	553	17	-	-	HYPH
cord-008530-yni0poh9	553	18	la	la	NNP
cord-008530-yni0poh9	553	19	or	or	CC
cord-008530-yni0poh9	553	20	RANTES	RANTES	NNPS
cord-008530-yni0poh9	553	21	.	.	.
cord-008530-yni0poh9	554	1	IL-8	IL-8	NNP
cord-008530-yni0poh9	554	2	levels	level	NNS
cord-008530-yni0poh9	554	3	were	be	VBD
cord-008530-yni0poh9	554	4	elevated	elevate	VBN
cord-008530-yni0poh9	554	5	at	at	IN
cord-008530-yni0poh9	554	6	4	4	CD
cord-008530-yni0poh9	554	7	to	to	TO
cord-008530-yni0poh9	554	8	8	8	CD
cord-008530-yni0poh9	554	9	hours	hour	NNS
cord-008530-yni0poh9	554	10	after	after	IN
cord-008530-yni0poh9	554	11	admission	admission	NN
cord-008530-yni0poh9	554	12	.	.	.
cord-008530-yni0poh9	555	1	By	by	IN
cord-008530-yni0poh9	555	2	contrast	contrast	NN
cord-008530-yni0poh9	555	3	,	,	,
cord-008530-yni0poh9	555	4	plasma	plasma	NN
cord-008530-yni0poh9	555	5	chemokine	chemokine	NN
cord-008530-yni0poh9	555	6	levels	level	NNS
cord-008530-yni0poh9	555	7	were	be	VBD
cord-008530-yni0poh9	555	8	considerably	considerably	RB
cord-008530-yni0poh9	555	9	lower	low	JJR
cord-008530-yni0poh9	555	10	than	than	IN
cord-008530-yni0poh9	555	11	CSF	CSF	NNP
cord-008530-yni0poh9	555	12	levels	level	NNS
cord-008530-yni0poh9	555	13	,	,	,
cord-008530-yni0poh9	555	14	pointing	point	VBG
cord-008530-yni0poh9	555	15	to	to	IN
cord-008530-yni0poh9	555	16	the	the	DT
cord-008530-yni0poh9	555	17	localized	localized	JJ
cord-008530-yni0poh9	555	18	nature	nature	NN
cord-008530-yni0poh9	555	19	of	of	IN
cord-008530-yni0poh9	555	20	the	the	DT
cord-008530-yni0poh9	555	21	CNS	CNS	NNP
cord-008530-yni0poh9	555	22	chemokine	chemokine	NN
cord-008530-yni0poh9	555	23	response	response	NN
cord-008530-yni0poh9	555	24	in	in	IN
cord-008530-yni0poh9	555	25	these	these	DT
cord-008530-yni0poh9	555	26	HSE-1	HSE-1	NNP
cord-008530-yni0poh9	555	27	patients	patient	NNS
cord-008530-yni0poh9	555	28	.	.	.
cord-008530-yni0poh9	556	1	A	a	DT
cord-008530-yni0poh9	556	2	comparison	comparison	NN
cord-008530-yni0poh9	556	3	of	of	IN
cord-008530-yni0poh9	556	4	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	556	5	levels	level	NNS
cord-008530-yni0poh9	556	6	with	with	IN
cord-008530-yni0poh9	556	7	clinical	clinical	JJ
cord-008530-yni0poh9	556	8	status	status	NN
cord-008530-yni0poh9	556	9	revealed	reveal	VBD
cord-008530-yni0poh9	556	10	a	a	DT
cord-008530-yni0poh9	556	11	high	high	JJ
cord-008530-yni0poh9	556	12	reciprocal	reciprocal	JJ
cord-008530-yni0poh9	556	13	correlation	correlation	NN
cord-008530-yni0poh9	556	14	.	.	.
cord-008530-yni0poh9	557	1	This	this	DT
cord-008530-yni0poh9	557	2	single	single	JJ
cord-008530-yni0poh9	557	3	clinical	clinical	JJ
cord-008530-yni0poh9	557	4	study	study	NN
cord-008530-yni0poh9	557	5	implicates	implicate	VBZ
cord-008530-yni0poh9	557	6	chemokines	chemokine	NNS
cord-008530-yni0poh9	557	7	,	,	,
cord-008530-yni0poh9	557	8	particularly	particularly	RB
cord-008530-yni0poh9	557	9	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	557	10	,	,	,
cord-008530-yni0poh9	557	11	in	in	IN
cord-008530-yni0poh9	557	12	the	the	DT
cord-008530-yni0poh9	557	13	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	557	14	of	of	IN
cord-008530-yni0poh9	557	15	HSE-1	HSE-1	NNP
cord-008530-yni0poh9	557	16	and	and	CC
cord-008530-yni0poh9	557	17	suggests	suggest	VBZ
cord-008530-yni0poh9	557	18	these	these	DT
cord-008530-yni0poh9	557	19	mediators	mediator	NNS
cord-008530-yni0poh9	557	20	may	may	MD
cord-008530-yni0poh9	557	21	be	be	VB
cord-008530-yni0poh9	557	22	useful	useful	JJ
cord-008530-yni0poh9	557	23	indicators	indicator	NNS
cord-008530-yni0poh9	557	24	to	to	TO
cord-008530-yni0poh9	557	25	determine	determine	VB
cord-008530-yni0poh9	557	26	the	the	DT
cord-008530-yni0poh9	557	27	stage	stage	NN
cord-008530-yni0poh9	557	28	and	and	CC
cord-008530-yni0poh9	557	29	severity	severity	NN
cord-008530-yni0poh9	557	30	of	of	IN
cord-008530-yni0poh9	557	31	riSE-1	rise-1	NN
cord-008530-yni0poh9	557	32	.	.	.
cord-008530-yni0poh9	558	1	Experimental	experimental	JJ
cord-008530-yni0poh9	558	2	studies	study	NNS
cord-008530-yni0poh9	558	3	of	of	IN
cord-008530-yni0poh9	558	4	HSV-1	hsv-1	NN
cord-008530-yni0poh9	558	5	in	in	IN
cord-008530-yni0poh9	558	6	mice	mouse	NNS
cord-008530-yni0poh9	558	7	,	,	,
cord-008530-yni0poh9	558	8	following	follow	VBG
cord-008530-yni0poh9	558	9	ocular	ocular	JJ
cord-008530-yni0poh9	558	10	infection	infection	NN
cord-008530-yni0poh9	558	11	,	,	,
cord-008530-yni0poh9	558	12	highlight	highlight	VB
cord-008530-yni0poh9	558	13	the	the	DT
cord-008530-yni0poh9	558	14	rapid	rapid	JJ
cord-008530-yni0poh9	558	15	and	and	CC
cord-008530-yni0poh9	558	16	sustained	sustain	VBD
cord-008530-yni0poh9	558	17	upregulation	upregulation	NN
cord-008530-yni0poh9	558	18	of	of	IN
cord-008530-yni0poh9	558	19	a	a	DT
cord-008530-yni0poh9	558	20	number	number	NN
cord-008530-yni0poh9	558	21	of	of	IN
cord-008530-yni0poh9	558	22	chemokine	chemokine	NN
cord-008530-yni0poh9	558	23	genes	gene	NNS
cord-008530-yni0poh9	558	24	including	include	VBG
cord-008530-yni0poh9	558	25	GRO	GRO	NNP
cord-008530-yni0poh9	558	26	-	-	HYPH
cord-008530-yni0poh9	558	27	a	a	NN
cord-008530-yni0poh9	558	28	,	,	,
cord-008530-yni0poh9	558	29	MIP	MIP	NNP
cord-008530-yni0poh9	558	30	-	-	HYPH
cord-008530-yni0poh9	558	31	I~	I~	NNP
cord-008530-yni0poh9	558	32	,	,	,
cord-008530-yni0poh9	558	33	MIP-2	MIP-2	NNP
cord-008530-yni0poh9	558	34	,	,	,
cord-008530-yni0poh9	558	35	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	558	36	,	,	,
cord-008530-yni0poh9	558	37	IP-10	IP-10	NNP
cord-008530-yni0poh9	558	38	,	,	,
cord-008530-yni0poh9	558	39	and	and	CC
cord-008530-yni0poh9	558	40	RANTES	RANTES	NNP
cord-008530-yni0poh9	558	41	(	(	-LRB-
cord-008530-yni0poh9	558	42	Carr	Carr	NNP
cord-008530-yni0poh9	558	43	et	et	FW
cord-008530-yni0poh9	558	44	al	al	NNP
cord-008530-yni0poh9	558	45	.	.	NNP
cord-008530-yni0poh9	558	46	,	,	,
cord-008530-yni0poh9	558	47	1998	1998	CD
cord-008530-yni0poh9	558	48	;	;	:
cord-008530-yni0poh9	558	49	Thomas	Thomas	NNP
cord-008530-yni0poh9	558	50	et	et	NNP
cord-008530-yni0poh9	558	51	al	al	NNP
cord-008530-yni0poh9	558	52	.	.	NNP
cord-008530-yni0poh9	558	53	,	,	,
cord-008530-yni0poh9	558	54	1998	1998	CD
cord-008530-yni0poh9	558	55	)	)	-RRB-
cord-008530-yni0poh9	558	56	.	.	.
cord-008530-yni0poh9	559	1	HSV	HSV	NNP
cord-008530-yni0poh9	559	2	stromal	stromal	NN
cord-008530-yni0poh9	559	3	keratitis	keratitis	NN
cord-008530-yni0poh9	559	4	,	,	,
cord-008530-yni0poh9	559	5	associated	associate	VBN
cord-008530-yni0poh9	559	6	with	with	IN
cord-008530-yni0poh9	559	7	productive	productive	JJ
cord-008530-yni0poh9	559	8	infection	infection	NN
cord-008530-yni0poh9	559	9	in	in	IN
cord-008530-yni0poh9	559	10	the	the	DT
cord-008530-yni0poh9	559	11	eye	eye	NN
cord-008530-yni0poh9	559	12	,	,	,
cord-008530-yni0poh9	559	13	results	result	NNS
cord-008530-yni0poh9	559	14	in	in	IN
cord-008530-yni0poh9	559	15	significant	significant	JJ
cord-008530-yni0poh9	559	16	accumulation	accumulation	NN
cord-008530-yni0poh9	559	17	of	of	IN
cord-008530-yni0poh9	559	18	PMN	PMN	NNP
cord-008530-yni0poh9	559	19	,	,	,
cord-008530-yni0poh9	559	20	which	which	WDT
cord-008530-yni0poh9	559	21	may	may	MD
cord-008530-yni0poh9	559	22	be	be	VB
cord-008530-yni0poh9	559	23	driven	drive	VBN
cord-008530-yni0poh9	559	24	by	by	IN
cord-008530-yni0poh9	559	25	the	the	DT
cord-008530-yni0poh9	559	26	presence	presence	NN
cord-008530-yni0poh9	559	27	in	in	IN
cord-008530-yni0poh9	559	28	particular	particular	JJ
cord-008530-yni0poh9	559	29	of	of	IN
cord-008530-yni0poh9	559	30	the	the	DT
cord-008530-yni0poh9	559	31	CXC	CXC	NNP
cord-008530-yni0poh9	559	32	chemokines	chemokine	NNS
cord-008530-yni0poh9	559	33	GRO	GRO	NNP
cord-008530-yni0poh9	559	34	-	-	HYPH
cord-008530-yni0poh9	559	35	a	a	NN
cord-008530-yni0poh9	559	36	and	and	CC
cord-008530-yni0poh9	559	37	MIP-2	mip-2	NN
cord-008530-yni0poh9	560	1	(	(	-LRB-
cord-008530-yni0poh9	560	2	Thomas	Thomas	NNP
cord-008530-yni0poh9	560	3	et	et	NNP
cord-008530-yni0poh9	560	4	al	al	NNP
cord-008530-yni0poh9	560	5	.	.	NNP
cord-008530-yni0poh9	560	6	,	,	,
cord-008530-yni0poh9	560	7	1998	1998	CD
cord-008530-yni0poh9	560	8	)	)	-RRB-
cord-008530-yni0poh9	560	9	.	.	.
cord-008530-yni0poh9	561	1	A	a	DT
cord-008530-yni0poh9	561	2	clinical	clinical	JJ
cord-008530-yni0poh9	561	3	survey	survey	NN
cord-008530-yni0poh9	561	4	of	of	IN
cord-008530-yni0poh9	561	5	chemokine	chemokine	JJ
cord-008530-yni0poh9	561	6	expression	expression	NN
cord-008530-yni0poh9	561	7	in	in	IN
cord-008530-yni0poh9	561	8	CSF	CSF	NNP
cord-008530-yni0poh9	561	9	in	in	IN
cord-008530-yni0poh9	561	10	patients	patient	NNS
cord-008530-yni0poh9	561	11	with	with	IN
cord-008530-yni0poh9	561	12	viral	viral	JJ
cord-008530-yni0poh9	561	13	meningitis	meningitis	NN
cord-008530-yni0poh9	561	14	,	,	,
cord-008530-yni0poh9	561	15	due	due	IN
cord-008530-yni0poh9	561	16	to	to	IN
cord-008530-yni0poh9	561	17	infection	infection	NN
cord-008530-yni0poh9	561	18	with	with	IN
cord-008530-yni0poh9	561	19	paramyxoviruses	paramyxovirus	NNS
cord-008530-yni0poh9	561	20	or	or	CC
cord-008530-yni0poh9	561	21	enteroviruses	enteroviruses	NNP
cord-008530-yni0poh9	561	22	,	,	,
cord-008530-yni0poh9	561	23	implicated	implicate	VBN
cord-008530-yni0poh9	561	24	IP-10	IP-10	NNP
cord-008530-yni0poh9	561	25	and	and	CC
cord-008530-yni0poh9	561	26	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	561	27	as	as	IN
cord-008530-yni0poh9	561	28	important	important	JJ
cord-008530-yni0poh9	561	29	contributory	contributory	JJ
cord-008530-yni0poh9	561	30	factors	factor	NNS
cord-008530-yni0poh9	561	31	in	in	IN
cord-008530-yni0poh9	561	32	the	the	DT
cord-008530-yni0poh9	561	33	accumulation	accumulation	NN
cord-008530-yni0poh9	561	34	of	of	IN
cord-008530-yni0poh9	561	35	activated	activate	VBN
cord-008530-yni0poh9	561	36	T	T	NNP
cord-008530-yni0poh9	561	37	cells	cell	NNS
cord-008530-yni0poh9	561	38	and	and	CC
cord-008530-yni0poh9	561	39	monocytes	monocyte	NNS
cord-008530-yni0poh9	561	40	in	in	IN
cord-008530-yni0poh9	561	41	the	the	DT
cord-008530-yni0poh9	561	42	CNS	CNS	NNP
cord-008530-yni0poh9	561	43	(	(	-LRB-
cord-008530-yni0poh9	561	44	Lahrtz	Lahrtz	NNP
cord-008530-yni0poh9	561	45	et	et	FW
cord-008530-yni0poh9	561	46	al	al	NNP
cord-008530-yni0poh9	561	47	.	.	NNP
cord-008530-yni0poh9	561	48	,	,	,
cord-008530-yni0poh9	561	49	1997	1997	CD
cord-008530-yni0poh9	561	50	)	)	-RRB-
cord-008530-yni0poh9	561	51	.	.	.
cord-008530-yni0poh9	562	1	Importantly	importantly	RB
cord-008530-yni0poh9	562	2	,	,	,
cord-008530-yni0poh9	562	3	this	this	DT
cord-008530-yni0poh9	562	4	study	study	NN
cord-008530-yni0poh9	562	5	formally	formally	RB
cord-008530-yni0poh9	562	6	demonstrated	demonstrate	VBD
cord-008530-yni0poh9	562	7	that	that	IN
cord-008530-yni0poh9	562	8	the	the	DT
cord-008530-yni0poh9	562	9	IP-10	IP-10	NNP
cord-008530-yni0poh9	562	10	and	and	CC
cord-008530-yni0poh9	562	11	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	562	12	levels	level	NNS
cord-008530-yni0poh9	562	13	in	in	IN
cord-008530-yni0poh9	562	14	CSF	CSF	NNP
cord-008530-yni0poh9	562	15	correlated	correlate	VBD
cord-008530-yni0poh9	562	16	with	with	IN
cord-008530-yni0poh9	562	17	leukocyte	leukocyte	NN
cord-008530-yni0poh9	562	18	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	562	19	activity	activity	NN
cord-008530-yni0poh9	562	20	.	.	.
cord-008530-yni0poh9	563	1	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	563	2	was	be	VBD
cord-008530-yni0poh9	563	3	identified	identify	VBN
cord-008530-yni0poh9	563	4	as	as	IN
cord-008530-yni0poh9	563	5	an	an	DT
cord-008530-yni0poh9	563	6	important	important	JJ
cord-008530-yni0poh9	563	7	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	563	8	for	for	IN
cord-008530-yni0poh9	563	9	PBMCs	pbmc	NNS
cord-008530-yni0poh9	563	10	while	while	IN
cord-008530-yni0poh9	563	11	the	the	DT
cord-008530-yni0poh9	563	12	combination	combination	NN
cord-008530-yni0poh9	563	13	of	of	IN
cord-008530-yni0poh9	563	14	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	563	15	and	and	CC
cord-008530-yni0poh9	563	16	IP-10	IP-10	NNP
cord-008530-yni0poh9	563	17	was	be	VBD
cord-008530-yni0poh9	563	18	required	require	VBN
cord-008530-yni0poh9	563	19	for	for	IN
cord-008530-yni0poh9	563	20	migration	migration	NN
cord-008530-yni0poh9	563	21	of	of	IN
cord-008530-yni0poh9	563	22	activated	activate	VBN
cord-008530-yni0poh9	563	23	T	T	NNP
cord-008530-yni0poh9	563	24	cells	cell	NNS
cord-008530-yni0poh9	563	25	.	.	.
cord-008530-yni0poh9	564	1	This	this	DT
cord-008530-yni0poh9	564	2	study	study	NN
cord-008530-yni0poh9	564	3	clearly	clearly	RB
cord-008530-yni0poh9	564	4	establishes	establish	VBZ
cord-008530-yni0poh9	564	5	a	a	DT
cord-008530-yni0poh9	564	6	direct	direct	JJ
cord-008530-yni0poh9	564	7	link	link	NN
cord-008530-yni0poh9	564	8	between	between	IN
cord-008530-yni0poh9	564	9	the	the	DT
cord-008530-yni0poh9	564	10	CNS	CNS	NNP
cord-008530-yni0poh9	564	11	expression	expression	NN
cord-008530-yni0poh9	564	12	of	of	IN
cord-008530-yni0poh9	564	13	the	the	DT
cord-008530-yni0poh9	564	14	chemokines	chemokine	NNS
cord-008530-yni0poh9	564	15	IP-10	IP-10	NNP
cord-008530-yni0poh9	564	16	and	and	CC
cord-008530-yni0poh9	564	17	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	564	18	and	and	CC
cord-008530-yni0poh9	564	19	CNS	CNS	NNP
cord-008530-yni0poh9	564	20	leukocytosis	leukocytosis	NN
cord-008530-yni0poh9	564	21	in	in	IN
cord-008530-yni0poh9	564	22	viral	viral	JJ
cord-008530-yni0poh9	564	23	meningitis	meningitis	NN
cord-008530-yni0poh9	564	24	.	.	.
cord-008530-yni0poh9	565	1	In	in	IN
cord-008530-yni0poh9	565	2	experimental	experimental	JJ
cord-008530-yni0poh9	565	3	studies	study	NNS
cord-008530-yni0poh9	565	4	,	,	,
cord-008530-yni0poh9	565	5	the	the	DT
cord-008530-yni0poh9	565	6	paramyxovirus	paramyxovirus	JJ
cord-008530-yni0poh9	565	7	Newcastle	Newcastle	NNP
cord-008530-yni0poh9	565	8	disease	disease	NN
cord-008530-yni0poh9	565	9	virus	virus	NN
cord-008530-yni0poh9	565	10	(	(	-LRB-
cord-008530-yni0poh9	565	11	NDV	NDV	NNP
cord-008530-yni0poh9	565	12	)	)	-RRB-
cord-008530-yni0poh9	565	13	induces	induce	VBZ
cord-008530-yni0poh9	565	14	IP-10	IP-10	NNP
cord-008530-yni0poh9	565	15	gene	gene	NN
cord-008530-yni0poh9	565	16	expression	expression	NN
cord-008530-yni0poh9	565	17	in	in	IN
cord-008530-yni0poh9	565	18	infected	infected	JJ
cord-008530-yni0poh9	565	19	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	565	20	and	and	CC
cord-008530-yni0poh9	565	21	microglia	microglia	NNS
cord-008530-yni0poh9	565	22	detectable	detectable	JJ
cord-008530-yni0poh9	565	23	by	by	IN
cord-008530-yni0poh9	565	24	3	3	CD
cord-008530-yni0poh9	565	25	hours	hour	NNS
cord-008530-yni0poh9	565	26	postinfection	postinfection	NN
cord-008530-yni0poh9	565	27	(	(	-LRB-
cord-008530-yni0poh9	565	28	Vanguri	Vanguri	NNP
cord-008530-yni0poh9	565	29	and	and	CC
cord-008530-yni0poh9	565	30	Farber	Farber	NNP
cord-008530-yni0poh9	565	31	,	,	,
cord-008530-yni0poh9	565	32	1994	1994	CD
cord-008530-yni0poh9	565	33	)	)	-RRB-
cord-008530-yni0poh9	565	34	.	.	.
cord-008530-yni0poh9	566	1	UV	uv	NN
cord-008530-yni0poh9	566	2	-	-	HYPH
cord-008530-yni0poh9	566	3	inactivated	inactivate	VBN
cord-008530-yni0poh9	566	4	NDV	NDV	NNP
cord-008530-yni0poh9	566	5	proved	prove	VBD
cord-008530-yni0poh9	566	6	to	to	TO
cord-008530-yni0poh9	566	7	be	be	VB
cord-008530-yni0poh9	566	8	as	as	RB
cord-008530-yni0poh9	566	9	effective	effective	JJ
cord-008530-yni0poh9	566	10	as	as	IN
cord-008530-yni0poh9	566	11	live	live	JJ
cord-008530-yni0poh9	566	12	virus	virus	NN
cord-008530-yni0poh9	566	13	in	in	IN
cord-008530-yni0poh9	566	14	inducing	induce	VBG
cord-008530-yni0poh9	566	15	IP-10	IP-10	NNP
cord-008530-yni0poh9	566	16	gene	gene	NN
cord-008530-yni0poh9	566	17	expression	expression	NN
cord-008530-yni0poh9	566	18	and	and	CC
cord-008530-yni0poh9	566	19	was	be	VBD
cord-008530-yni0poh9	566	20	not	not	RB
cord-008530-yni0poh9	566	21	blocked	block	VBN
cord-008530-yni0poh9	566	22	by	by	IN
cord-008530-yni0poh9	566	23	the	the	DT
cord-008530-yni0poh9	566	24	protein	protein	NN
cord-008530-yni0poh9	566	25	synthesis	synthesis	NN
cord-008530-yni0poh9	566	26	inhibitor	inhibitor	NN
cord-008530-yni0poh9	566	27	cycloheximide	cycloheximide	NN
cord-008530-yni0poh9	566	28	,	,	,
cord-008530-yni0poh9	566	29	indicating	indicate	VBG
cord-008530-yni0poh9	566	30	that	that	IN
cord-008530-yni0poh9	566	31	the	the	DT
cord-008530-yni0poh9	566	32	IP-10	IP-10	NNP
cord-008530-yni0poh9	566	33	gene	gene	NN
cord-008530-yni0poh9	566	34	functions	function	NNS
cord-008530-yni0poh9	566	35	as	as	IN
cord-008530-yni0poh9	566	36	an	an	DT
cord-008530-yni0poh9	566	37	immediate	immediate	JJ
cord-008530-yni0poh9	566	38	early	early	JJ
cord-008530-yni0poh9	566	39	response	response	NN
cord-008530-yni0poh9	566	40	gene	gene	NN
cord-008530-yni0poh9	566	41	,	,	,
cord-008530-yni0poh9	566	42	following	follow	VBG
cord-008530-yni0poh9	566	43	NDV	ndv	JJ
cord-008530-yni0poh9	566	44	infection	infection	NN
cord-008530-yni0poh9	566	45	.	.	.
cord-008530-yni0poh9	567	1	Similar	similar	JJ
cord-008530-yni0poh9	567	2	to	to	IN
cord-008530-yni0poh9	567	3	NDV	NDV	NNP
cord-008530-yni0poh9	567	4	,	,	,
cord-008530-yni0poh9	567	5	measles	measles	NN
cord-008530-yni0poh9	567	6	virus	virus	NN
cord-008530-yni0poh9	567	7	(	(	-LRB-
cord-008530-yni0poh9	567	8	MV	MV	NNP
cord-008530-yni0poh9	567	9	)	)	-RRB-
cord-008530-yni0poh9	567	10	is	be	VBZ
cord-008530-yni0poh9	567	11	a	a	DT
cord-008530-yni0poh9	567	12	paramyxovirus	paramyxovirus	NN
cord-008530-yni0poh9	567	13	that	that	WDT
cord-008530-yni0poh9	567	14	induces	induce	VBZ
cord-008530-yni0poh9	567	15	IP-10	IP-10	NNP
cord-008530-yni0poh9	567	16	gene	gene	NN
cord-008530-yni0poh9	567	17	expression	expression	NN
cord-008530-yni0poh9	567	18	in	in	IN
cord-008530-yni0poh9	567	19	human	human	JJ
cord-008530-yni0poh9	567	20	glioblastoma	glioblastoma	NN
cord-008530-yni0poh9	567	21	cells	cell	NNS
cord-008530-yni0poh9	567	22	(	(	-LRB-
cord-008530-yni0poh9	567	23	Nazar	Nazar	NNP
cord-008530-yni0poh9	567	24	et	et	FW
cord-008530-yni0poh9	567	25	al	al	NNP
cord-008530-yni0poh9	567	26	.	.	NNP
cord-008530-yni0poh9	567	27	,	,	,
cord-008530-yni0poh9	567	28	1997	1997	CD
cord-008530-yni0poh9	567	29	)	)	-RRB-
cord-008530-yni0poh9	567	30	.	.	.
cord-008530-yni0poh9	568	1	The	the	DT
cord-008530-yni0poh9	568	2	promoter	promoter	NN
cord-008530-yni0poh9	568	3	requirements	requirement	VBZ
cord-008530-yni0poh9	568	4	for	for	IN
cord-008530-yni0poh9	568	5	the	the	DT
cord-008530-yni0poh9	568	6	induction	induction	NN
cord-008530-yni0poh9	568	7	of	of	IN
cord-008530-yni0poh9	568	8	IP-10	IP-10	NNP
cord-008530-yni0poh9	568	9	gene	gene	NN
cord-008530-yni0poh9	568	10	expression	expression	NN
cord-008530-yni0poh9	568	11	are	be	VBP
cord-008530-yni0poh9	568	12	similar	similar	JJ
cord-008530-yni0poh9	568	13	for	for	IN
cord-008530-yni0poh9	568	14	IFN-~	IFN-~	NNP
cord-008530-yni0poh9	568	15	and	and	CC
cord-008530-yni0poh9	568	16	MV	MV	NNP
cord-008530-yni0poh9	568	17	;	;	:
cord-008530-yni0poh9	568	18	however	however	RB
cord-008530-yni0poh9	568	19	,	,	,
cord-008530-yni0poh9	568	20	these	these	DT
cord-008530-yni0poh9	568	21	two	two	CD
cord-008530-yni0poh9	568	22	stimuli	stimulus	NNS
cord-008530-yni0poh9	568	23	use	use	VBP
cord-008530-yni0poh9	568	24	different	different	JJ
cord-008530-yni0poh9	568	25	combinations	combination	NNS
cord-008530-yni0poh9	568	26	of	of	IN
cord-008530-yni0poh9	568	27	DNA	dna	NN
cord-008530-yni0poh9	568	28	binding	binding	NN
cord-008530-yni0poh9	568	29	factors	factor	NNS
cord-008530-yni0poh9	568	30	,	,	,
cord-008530-yni0poh9	568	31	with	with	IN
cord-008530-yni0poh9	568	32	STAT	stat	NN
cord-008530-yni0poh9	568	33	1	1	CD
cord-008530-yni0poh9	568	34	or	or	CC
cord-008530-yni0poh9	568	35	NF~	nf~	NN
cord-008530-yni0poh9	569	1	B	b	NN
cord-008530-yni0poh9	569	2	being	be	VBG
cord-008530-yni0poh9	569	3	more	more	RBR
cord-008530-yni0poh9	569	4	important	important	JJ
cord-008530-yni0poh9	569	5	in	in	IN
cord-008530-yni0poh9	569	6	the	the	DT
cord-008530-yni0poh9	569	7	direct	direct	JJ
cord-008530-yni0poh9	569	8	induction	induction	NN
cord-008530-yni0poh9	569	9	of	of	IN
cord-008530-yni0poh9	569	10	IP-10	IP-10	NNP
cord-008530-yni0poh9	569	11	by	by	IN
cord-008530-yni0poh9	569	12	IFN-~	IFN-~	NNP
cord-008530-yni0poh9	569	13	or	or	CC
cord-008530-yni0poh9	569	14	MV	MV	NNP
cord-008530-yni0poh9	569	15	,	,	,
cord-008530-yni0poh9	569	16	respectively	respectively	RB
cord-008530-yni0poh9	569	17	.	.	.
cord-008530-yni0poh9	570	1	While	while	IN
cord-008530-yni0poh9	570	2	it	-PRON-	PRP
cord-008530-yni0poh9	570	3	is	be	VBZ
cord-008530-yni0poh9	570	4	presently	presently	RB
cord-008530-yni0poh9	570	5	unknown	unknown	JJ
cord-008530-yni0poh9	570	6	whether	whether	IN
cord-008530-yni0poh9	570	7	these	these	DT
cord-008530-yni0poh9	570	8	paramyxoviruses	paramyxovirus	NNS
cord-008530-yni0poh9	570	9	induce	induce	VBP
cord-008530-yni0poh9	570	10	the	the	DT
cord-008530-yni0poh9	570	11	expression	expression	NN
cord-008530-yni0poh9	570	12	of	of	IN
cord-008530-yni0poh9	570	13	other	other	JJ
cord-008530-yni0poh9	570	14	chemokine	chemokine	NN
cord-008530-yni0poh9	570	15	genes	gene	NNS
cord-008530-yni0poh9	570	16	,	,	,
cord-008530-yni0poh9	570	17	their	-PRON-	PRP$
cord-008530-yni0poh9	570	18	potent	potent	JJ
cord-008530-yni0poh9	570	19	ability	ability	NN
cord-008530-yni0poh9	570	20	to	to	TO
cord-008530-yni0poh9	570	21	directly	directly	RB
cord-008530-yni0poh9	570	22	induce	induce	VB
cord-008530-yni0poh9	570	23	IP-10	IP-10	NNP
cord-008530-yni0poh9	570	24	expression	expression	NN
cord-008530-yni0poh9	570	25	by	by	IN
cord-008530-yni0poh9	570	26	glial	glial	JJ
cord-008530-yni0poh9	570	27	cells	cell	NNS
cord-008530-yni0poh9	570	28	may	may	MD
cord-008530-yni0poh9	570	29	constitute	constitute	VB
cord-008530-yni0poh9	570	30	a	a	DT
cord-008530-yni0poh9	570	31	significant	significant	JJ
cord-008530-yni0poh9	570	32	CNS	CNS	NNP
cord-008530-yni0poh9	570	33	source	source	NN
cord-008530-yni0poh9	570	34	of	of	IN
cord-008530-yni0poh9	570	35	production	production	NN
cord-008530-yni0poh9	570	36	of	of	IN
cord-008530-yni0poh9	570	37	this	this	DT
cord-008530-yni0poh9	570	38	chemokine	chemokine	NN
cord-008530-yni0poh9	570	39	during	during	IN
cord-008530-yni0poh9	570	40	viral	viral	JJ
cord-008530-yni0poh9	570	41	meningitis	meningitis	NN
cord-008530-yni0poh9	570	42	.	.	.
cord-008530-yni0poh9	571	1	Mouse	mouse	NN
cord-008530-yni0poh9	571	2	adenovirus	adenovirus	NN
cord-008530-yni0poh9	571	3	-	-	HYPH
cord-008530-yni0poh9	571	4	type	type	NN
cord-008530-yni0poh9	571	5	1	1	CD
cord-008530-yni0poh9	571	6	(	(	-LRB-
cord-008530-yni0poh9	571	7	MAV-1	MAV-1	NNP
cord-008530-yni0poh9	571	8	)	)	-RRB-
cord-008530-yni0poh9	571	9	is	be	VBZ
cord-008530-yni0poh9	571	10	a	a	DT
cord-008530-yni0poh9	571	11	double	double	RB
cord-008530-yni0poh9	571	12	-	-	HYPH
cord-008530-yni0poh9	571	13	stranded	stranded	JJ
cord-008530-yni0poh9	571	14	DNA	dna	NN
cord-008530-yni0poh9	571	15	virus	virus	NN
cord-008530-yni0poh9	571	16	that	that	WDT
cord-008530-yni0poh9	571	17	causes	cause	VBZ
cord-008530-yni0poh9	571	18	a	a	DT
cord-008530-yni0poh9	571	19	fatal	fatal	JJ
cord-008530-yni0poh9	571	20	hemorrhagic	hemorrhagic	JJ
cord-008530-yni0poh9	571	21	encephalopathy	encephalopathy	NN
cord-008530-yni0poh9	571	22	in	in	IN
cord-008530-yni0poh9	571	23	C57B1/6	C57B1/6	NNP
cord-008530-yni0poh9	571	24	mice	mouse	NNS
cord-008530-yni0poh9	571	25	within	within	IN
cord-008530-yni0poh9	571	26	4	4	CD
cord-008530-yni0poh9	571	27	-	-	SYM
cord-008530-yni0poh9	571	28	6	6	CD
cord-008530-yni0poh9	571	29	days	day	NNS
cord-008530-yni0poh9	572	1	(	(	-LRB-
cord-008530-yni0poh9	572	2	Guida	Guida	NNP
cord-008530-yni0poh9	572	3	et	et	FW
cord-008530-yni0poh9	572	4	al	al	NNP
cord-008530-yni0poh9	572	5	.	.	NNP
cord-008530-yni0poh9	572	6	,	,	,
cord-008530-yni0poh9	572	7	1995	1995	CD
cord-008530-yni0poh9	572	8	)	)	-RRB-
cord-008530-yni0poh9	572	9	,	,	,
cord-008530-yni0poh9	572	10	along	along	IN
cord-008530-yni0poh9	572	11	with	with	IN
cord-008530-yni0poh9	572	12	infection	infection	NN
cord-008530-yni0poh9	572	13	of	of	IN
cord-008530-yni0poh9	572	14	cerebrovascular	cerebrovascular	JJ
cord-008530-yni0poh9	572	15	endothelial	endothelial	JJ
cord-008530-yni0poh9	572	16	cells	cell	NNS
cord-008530-yni0poh9	572	17	.	.	.
cord-008530-yni0poh9	573	1	Chemokine	chemokine	JJ
cord-008530-yni0poh9	573	2	gene	gene	NN
cord-008530-yni0poh9	573	3	expression	expression	NN
cord-008530-yni0poh9	573	4	was	be	VBD
cord-008530-yni0poh9	573	5	investigated	investigate	VBN
cord-008530-yni0poh9	573	6	and	and	CC
cord-008530-yni0poh9	573	7	prominent	prominent	JJ
cord-008530-yni0poh9	573	8	induction	induction	NN
cord-008530-yni0poh9	573	9	of	of	IN
cord-008530-yni0poh9	573	10	IP-10	IP-10	NNP
cord-008530-yni0poh9	573	11	was	be	VBD
cord-008530-yni0poh9	573	12	observed	observe	VBN
cord-008530-yni0poh9	573	13	in	in	IN
cord-008530-yni0poh9	573	14	the	the	DT
cord-008530-yni0poh9	573	15	spleen	spleen	NNS
cord-008530-yni0poh9	573	16	and	and	CC
cord-008530-yni0poh9	573	17	CNS	CNS	NNP
cord-008530-yni0poh9	573	18	of	of	IN
cord-008530-yni0poh9	573	19	susceptible	susceptible	JJ
cord-008530-yni0poh9	573	20	mice	mouse	NNS
cord-008530-yni0poh9	573	21	,	,	,
cord-008530-yni0poh9	573	22	whereas	whereas	IN
cord-008530-yni0poh9	573	23	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	573	24	and	and	CC
cord-008530-yni0poh9	573	25	MIP-2	MIP-2	NNP
cord-008530-yni0poh9	573	26	,	,	,
cord-008530-yni0poh9	573	27	respectively	respectively	RB
cord-008530-yni0poh9	573	28	,	,	,
cord-008530-yni0poh9	573	29	were	be	VBD
cord-008530-yni0poh9	573	30	found	find	VBN
cord-008530-yni0poh9	573	31	in	in	IN
cord-008530-yni0poh9	573	32	the	the	DT
cord-008530-yni0poh9	573	33	spleen	spleen	NN
cord-008530-yni0poh9	573	34	and	and	CC
cord-008530-yni0poh9	573	35	brain	brain	NN
cord-008530-yni0poh9	573	36	of	of	IN
cord-008530-yni0poh9	573	37	resistant	resistant	JJ
cord-008530-yni0poh9	573	38	mice	mouse	NNS
cord-008530-yni0poh9	574	1	(	(	-LRB-
cord-008530-yni0poh9	574	2	Charles	Charles	NNP
cord-008530-yni0poh9	574	3	et	et	NNP
cord-008530-yni0poh9	574	4	al	al	NNP
cord-008530-yni0poh9	574	5	.	.	NNP
cord-008530-yni0poh9	574	6	,	,	,
cord-008530-yni0poh9	574	7	1999	1999	CD
cord-008530-yni0poh9	574	8	)	)	-RRB-
cord-008530-yni0poh9	574	9	.	.	.
cord-008530-yni0poh9	575	1	Vascular	vascular	JJ
cord-008530-yni0poh9	575	2	endothelium	endothelium	NN
cord-008530-yni0poh9	575	3	and	and	CC
cord-008530-yni0poh9	575	4	CNS	CNS	NNP
cord-008530-yni0poh9	575	5	glia	glia	NNS
cord-008530-yni0poh9	575	6	were	be	VBD
cord-008530-yni0poh9	575	7	identified	identify	VBN
cord-008530-yni0poh9	575	8	as	as	IN
cord-008530-yni0poh9	575	9	sites	site	NNS
cord-008530-yni0poh9	575	10	of	of	IN
cord-008530-yni0poh9	575	11	IP-10	IP-10	NNP
cord-008530-yni0poh9	575	12	mRNA	mRNA	NNP
cord-008530-yni0poh9	575	13	expression	expression	NN
cord-008530-yni0poh9	575	14	in	in	IN
cord-008530-yni0poh9	575	15	susceptible	susceptible	JJ
cord-008530-yni0poh9	575	16	animals	animal	NNS
cord-008530-yni0poh9	575	17	.	.	.
cord-008530-yni0poh9	576	1	In	in	IN
cord-008530-yni0poh9	576	2	the	the	DT
cord-008530-yni0poh9	576	3	normal	normal	JJ
cord-008530-yni0poh9	576	4	mammalian	mammalian	JJ
cord-008530-yni0poh9	576	5	CNS	CNS	NNP
cord-008530-yni0poh9	576	6	,	,	,
cord-008530-yni0poh9	576	7	the	the	DT
cord-008530-yni0poh9	576	8	number	number	NN
cord-008530-yni0poh9	576	9	of	of	IN
cord-008530-yni0poh9	576	10	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	576	11	present	present	JJ
cord-008530-yni0poh9	576	12	in	in	IN
cord-008530-yni0poh9	576	13	the	the	DT
cord-008530-yni0poh9	576	14	brain	brain	NN
cord-008530-yni0poh9	576	15	is	be	VBZ
cord-008530-yni0poh9	576	16	scant	scant	JJ
cord-008530-yni0poh9	576	17	.	.	.
cord-008530-yni0poh9	577	1	However	however	RB
cord-008530-yni0poh9	577	2	,	,	,
cord-008530-yni0poh9	577	3	these	these	DT
cord-008530-yni0poh9	577	4	cells	cell	NNS
cord-008530-yni0poh9	577	5	are	be	VBP
cord-008530-yni0poh9	577	6	attracted	attract	VBN
cord-008530-yni0poh9	577	7	to	to	IN
cord-008530-yni0poh9	577	8	,	,	,
cord-008530-yni0poh9	577	9	and	and	CC
cord-008530-yni0poh9	577	10	accu-158	accu-158	NNP
cord-008530-yni0poh9	577	11	VALI	vali	NN
cord-008530-yni0poh9	577	12	~	~	NFP
cord-008530-yni0poh9	577	13	RIE	RIE	NNP
cord-008530-yni0poh9	577	14	C.	C.	NNP
cord-008530-yni0poh9	577	15	ASENSIO	ASENSIO	NNP
cord-008530-yni0poh9	577	16	AND	and	CC
cord-008530-yni0poh9	577	17	IAIN	IAIN	NNP
cord-008530-yni0poh9	578	1	L.	L.	NNP
cord-008530-yni0poh9	578	2	CAMPBELL	CAMPBELL	NNP
cord-008530-yni0poh9	578	3	mulate	mulate	NNP
cord-008530-yni0poh9	578	4	in	in	IN
cord-008530-yni0poh9	578	5	,	,	,
cord-008530-yni0poh9	578	6	a	a	DT
cord-008530-yni0poh9	578	7	variety	variety	NN
cord-008530-yni0poh9	578	8	of	of	IN
cord-008530-yni0poh9	578	9	pathologic	pathologic	JJ
cord-008530-yni0poh9	578	10	states	state	NNS
cord-008530-yni0poh9	578	11	,	,	,
cord-008530-yni0poh9	578	12	many	many	JJ
cord-008530-yni0poh9	578	13	involving	involve	VBG
cord-008530-yni0poh9	578	14	viral	viral	JJ
cord-008530-yni0poh9	578	15	infection	infection	NN
cord-008530-yni0poh9	578	16	.	.	.
cord-008530-yni0poh9	579	1	Although	although	IN
cord-008530-yni0poh9	579	2	leukocyte	leukocyte	NN
cord-008530-yni0poh9	579	3	migration	migration	NN
cord-008530-yni0poh9	579	4	into	into	IN
cord-008530-yni0poh9	579	5	local	local	JJ
cord-008530-yni0poh9	579	6	tissue	tissue	NN
cord-008530-yni0poh9	579	7	compartments	compartment	NNS
cord-008530-yni0poh9	579	8	such	such	JJ
cord-008530-yni0poh9	579	9	as	as	IN
cord-008530-yni0poh9	579	10	the	the	DT
cord-008530-yni0poh9	579	11	CNS	CNS	NNP
cord-008530-yni0poh9	579	12	is	be	VBZ
cord-008530-yni0poh9	579	13	a	a	DT
cord-008530-yni0poh9	579	14	multifactorial	multifactorial	JJ
cord-008530-yni0poh9	579	15	process	process	NN
cord-008530-yni0poh9	579	16	,	,	,
cord-008530-yni0poh9	579	17	it	-PRON-	PRP
cord-008530-yni0poh9	579	18	has	have	VBZ
cord-008530-yni0poh9	579	19	become	become	VBN
cord-008530-yni0poh9	579	20	clear	clear	JJ
cord-008530-yni0poh9	579	21	that	that	IN
cord-008530-yni0poh9	579	22	chemokines	chemokine	NNS
cord-008530-yni0poh9	579	23	are	be	VBP
cord-008530-yni0poh9	579	24	pivotal	pivotal	JJ
cord-008530-yni0poh9	579	25	components	component	NNS
cord-008530-yni0poh9	579	26	of	of	IN
cord-008530-yni0poh9	579	27	this	this	DT
cord-008530-yni0poh9	579	28	process	process	NN
cord-008530-yni0poh9	579	29	,	,	,
cord-008530-yni0poh9	579	30	providing	provide	VBG
cord-008530-yni0poh9	579	31	a	a	DT
cord-008530-yni0poh9	579	32	necessary	necessary	JJ
cord-008530-yni0poh9	579	33	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	579	34	signal	signal	NN
cord-008530-yni0poh9	579	35	for	for	IN
cord-008530-yni0poh9	579	36	leukocyte	leukocyte	NN
cord-008530-yni0poh9	579	37	recruitment	recruitment	NN
cord-008530-yni0poh9	579	38	.	.	.
cord-008530-yni0poh9	580	1	Generation	generation	NN
cord-008530-yni0poh9	580	2	of	of	IN
cord-008530-yni0poh9	580	3	this	this	DT
cord-008530-yni0poh9	580	4	signal	signal	NN
cord-008530-yni0poh9	580	5	in	in	IN
cord-008530-yni0poh9	580	6	CNS	CNS	NNP
cord-008530-yni0poh9	580	7	viral	viral	JJ
cord-008530-yni0poh9	580	8	infection	infection	NN
cord-008530-yni0poh9	580	9	may	may	MD
cord-008530-yni0poh9	580	10	involve	involve	VB
cord-008530-yni0poh9	580	11	localized	localized	JJ
cord-008530-yni0poh9	580	12	production	production	NN
cord-008530-yni0poh9	580	13	of	of	IN
cord-008530-yni0poh9	580	14	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	580	15	chemokines	chemokine	NNS
cord-008530-yni0poh9	580	16	by	by	IN
cord-008530-yni0poh9	580	17	cells	cell	NNS
cord-008530-yni0poh9	580	18	intrinsic	intrinsic	JJ
cord-008530-yni0poh9	580	19	to	to	IN
cord-008530-yni0poh9	580	20	the	the	DT
cord-008530-yni0poh9	580	21	brain	brain	NN
cord-008530-yni0poh9	580	22	,	,	,
cord-008530-yni0poh9	580	23	including	include	VBG
cord-008530-yni0poh9	580	24	the	the	DT
cord-008530-yni0poh9	580	25	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	580	26	and	and	CC
cord-008530-yni0poh9	580	27	microglia	microglia	NNS
cord-008530-yni0poh9	580	28	.	.	.
cord-008530-yni0poh9	581	1	The	the	DT
cord-008530-yni0poh9	581	2	activated	activate	VBN
cord-008530-yni0poh9	581	3	glia	glia	NNS
cord-008530-yni0poh9	581	4	have	have	VBP
cord-008530-yni0poh9	581	5	the	the	DT
cord-008530-yni0poh9	581	6	potential	potential	NN
cord-008530-yni0poh9	581	7	to	to	TO
cord-008530-yni0poh9	581	8	produce	produce	VB
cord-008530-yni0poh9	581	9	a	a	DT
cord-008530-yni0poh9	581	10	spectrum	spectrum	NN
cord-008530-yni0poh9	581	11	of	of	IN
cord-008530-yni0poh9	581	12	CC	CC	NNP
cord-008530-yni0poh9	581	13	and	and	CC
cord-008530-yni0poh9	581	14	CXC	CXC	NNP
cord-008530-yni0poh9	581	15	chemokines	chemokine	NNS
cord-008530-yni0poh9	581	16	that	that	WDT
cord-008530-yni0poh9	581	17	may	may	MD
cord-008530-yni0poh9	581	18	vary	vary	VB
cord-008530-yni0poh9	581	19	,	,	,
cord-008530-yni0poh9	581	20	depending	depend	VBG
cord-008530-yni0poh9	581	21	on	on	IN
cord-008530-yni0poh9	581	22	the	the	DT
cord-008530-yni0poh9	581	23	nature	nature	NN
cord-008530-yni0poh9	581	24	of	of	IN
cord-008530-yni0poh9	581	25	the	the	DT
cord-008530-yni0poh9	581	26	invading	invade	VBG
cord-008530-yni0poh9	581	27	pathogen	pathogen	NN
cord-008530-yni0poh9	581	28	.	.	.
cord-008530-yni0poh9	582	1	This	this	DT
cord-008530-yni0poh9	582	2	in	in	IN
cord-008530-yni0poh9	582	3	turn	turn	NN
cord-008530-yni0poh9	582	4	will	will	MD
cord-008530-yni0poh9	582	5	determine	determine	VB
cord-008530-yni0poh9	582	6	the	the	DT
cord-008530-yni0poh9	582	7	qualitative	qualitative	JJ
cord-008530-yni0poh9	582	8	makeup	makeup	NN
cord-008530-yni0poh9	582	9	of	of	IN
cord-008530-yni0poh9	582	10	the	the	DT
cord-008530-yni0poh9	582	11	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	582	12	recruited	recruit	VBN
cord-008530-yni0poh9	582	13	to	to	IN
cord-008530-yni0poh9	582	14	the	the	DT
cord-008530-yni0poh9	582	15	brain	brain	NN
cord-008530-yni0poh9	582	16	.	.	.
cord-008530-yni0poh9	583	1	It	-PRON-	PRP
cord-008530-yni0poh9	583	2	is	be	VBZ
cord-008530-yni0poh9	583	3	important	important	JJ
cord-008530-yni0poh9	583	4	to	to	TO
cord-008530-yni0poh9	583	5	note	note	VB
cord-008530-yni0poh9	583	6	,	,	,
cord-008530-yni0poh9	583	7	however	however	RB
cord-008530-yni0poh9	583	8	,	,	,
cord-008530-yni0poh9	583	9	that	that	IN
cord-008530-yni0poh9	583	10	how	how	WRB
cord-008530-yni0poh9	583	11	a	a	DT
cord-008530-yni0poh9	583	12	chemokine	chemokine	NN
cord-008530-yni0poh9	583	13	that	that	WDT
cord-008530-yni0poh9	583	14	is	be	VBZ
cord-008530-yni0poh9	583	15	secreted	secrete	VBN
cord-008530-yni0poh9	583	16	by	by	IN
cord-008530-yni0poh9	583	17	a	a	DT
cord-008530-yni0poh9	583	18	parenchymally	parenchymally	RB
cord-008530-yni0poh9	583	19	located	locate	VBN
cord-008530-yni0poh9	583	20	glial	glial	JJ
cord-008530-yni0poh9	583	21	cell	cell	NN
cord-008530-yni0poh9	583	22	is	be	VBZ
cord-008530-yni0poh9	583	23	"	"	``
cord-008530-yni0poh9	583	24	sensed	sense	VBN
cord-008530-yni0poh9	583	25	"	"	''
cord-008530-yni0poh9	583	26	by	by	IN
cord-008530-yni0poh9	583	27	circulating	circulate	VBG
cord-008530-yni0poh9	583	28	peripheral	peripheral	JJ
cord-008530-yni0poh9	583	29	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	583	30	is	be	VBZ
cord-008530-yni0poh9	583	31	unclear	unclear	JJ
cord-008530-yni0poh9	583	32	at	at	IN
cord-008530-yni0poh9	583	33	this	this	DT
cord-008530-yni0poh9	583	34	time	time	NN
cord-008530-yni0poh9	583	35	.	.	.
cord-008530-yni0poh9	584	1	Roles	role	NNS
cord-008530-yni0poh9	584	2	beyond	beyond	IN
cord-008530-yni0poh9	584	3	leukocyte	leukocyte	NN
cord-008530-yni0poh9	584	4	chemoattraction	chemoattraction	NN
cord-008530-yni0poh9	584	5	are	be	VBP
cord-008530-yni0poh9	584	6	implied	imply	VBN
cord-008530-yni0poh9	584	7	for	for	IN
cord-008530-yni0poh9	584	8	the	the	DT
cord-008530-yni0poh9	584	9	chemokines	chemokine	NNS
cord-008530-yni0poh9	584	10	and	and	CC
cord-008530-yni0poh9	584	11	their	-PRON-	PRP$
cord-008530-yni0poh9	584	12	receptors	receptor	NNS
cord-008530-yni0poh9	584	13	.	.	.
cord-008530-yni0poh9	585	1	Studies	study	NNS
cord-008530-yni0poh9	585	2	of	of	IN
cord-008530-yni0poh9	585	3	HIV	HIV	NNP
cord-008530-yni0poh9	585	4	highlight	highlight	VBP
cord-008530-yni0poh9	585	5	the	the	DT
cord-008530-yni0poh9	585	6	dynamic	dynamic	JJ
cord-008530-yni0poh9	585	7	relationship	relationship	NN
cord-008530-yni0poh9	585	8	between	between	IN
cord-008530-yni0poh9	585	9	chemokine	chemokine	NN
cord-008530-yni0poh9	585	10	receptor	receptor	NN
cord-008530-yni0poh9	585	11	usage	usage	NN
cord-008530-yni0poh9	585	12	and	and	CC
cord-008530-yni0poh9	585	13	tropism	tropism	NN
cord-008530-yni0poh9	585	14	for	for	IN
cord-008530-yni0poh9	585	15	different	different	JJ
cord-008530-yni0poh9	585	16	isolates	isolate	NNS
cord-008530-yni0poh9	585	17	of	of	IN
cord-008530-yni0poh9	585	18	HIV	HIV	NNP
cord-008530-yni0poh9	585	19	.	.	.
cord-008530-yni0poh9	586	1	On	on	IN
cord-008530-yni0poh9	586	2	the	the	DT
cord-008530-yni0poh9	586	3	other	other	JJ
cord-008530-yni0poh9	586	4	hand	hand	NN
cord-008530-yni0poh9	586	5	,	,	,
cord-008530-yni0poh9	586	6	the	the	DT
cord-008530-yni0poh9	586	7	fact	fact	NN
cord-008530-yni0poh9	586	8	that	that	IN
cord-008530-yni0poh9	586	9	chemokine	chemokine	NN
cord-008530-yni0poh9	586	10	receptor	receptor	NN
cord-008530-yni0poh9	586	11	ligands	ligand	NNS
cord-008530-yni0poh9	586	12	are	be	VBP
cord-008530-yni0poh9	586	13	effective	effective	JJ
cord-008530-yni0poh9	586	14	inhibitors	inhibitor	NNS
cord-008530-yni0poh9	586	15	of	of	IN
cord-008530-yni0poh9	586	16	HIV	HIV	NNP
cord-008530-yni0poh9	586	17	entry	entry	NN
cord-008530-yni0poh9	586	18	into	into	IN
cord-008530-yni0poh9	586	19	target	target	NN
cord-008530-yni0poh9	586	20	cells	cell	NNS
cord-008530-yni0poh9	586	21	suggests	suggest	VBZ
cord-008530-yni0poh9	586	22	their	-PRON-	PRP$
cord-008530-yni0poh9	586	23	local	local	JJ
cord-008530-yni0poh9	586	24	production	production	NN
cord-008530-yni0poh9	586	25	may	may	MD
cord-008530-yni0poh9	586	26	serve	serve	VB
cord-008530-yni0poh9	586	27	as	as	IN
cord-008530-yni0poh9	586	28	a	a	DT
cord-008530-yni0poh9	586	29	host	host	NN
cord-008530-yni0poh9	586	30	response	response	NN
cord-008530-yni0poh9	586	31	to	to	TO
cord-008530-yni0poh9	586	32	limit	limit	VB
cord-008530-yni0poh9	586	33	further	further	JJ
cord-008530-yni0poh9	586	34	spread	spread	NN
cord-008530-yni0poh9	586	35	of	of	IN
cord-008530-yni0poh9	586	36	the	the	DT
cord-008530-yni0poh9	586	37	infectious	infectious	JJ
cord-008530-yni0poh9	586	38	agent	agent	NN
cord-008530-yni0poh9	586	39	.	.	.
cord-008530-yni0poh9	587	1	Some	some	DT
cord-008530-yni0poh9	587	2	chemokines	chemokine	NNS
cord-008530-yni0poh9	587	3	such	such	JJ
cord-008530-yni0poh9	587	4	as	as	IN
cord-008530-yni0poh9	587	5	IP-10	IP-10	NNP
cord-008530-yni0poh9	587	6	are	be	VBP
cord-008530-yni0poh9	587	7	documented	document	VBN
cord-008530-yni0poh9	587	8	as	as	IN
cord-008530-yni0poh9	587	9	having	have	VBG
cord-008530-yni0poh9	587	10	direct	direct	JJ
cord-008530-yni0poh9	587	11	antiviral	antiviral	JJ
cord-008530-yni0poh9	587	12	functions	function	NNS
cord-008530-yni0poh9	587	13	.	.	.
cord-008530-yni0poh9	588	1	Whether	whether	IN
cord-008530-yni0poh9	588	2	this	this	DT
cord-008530-yni0poh9	588	3	is	be	VBZ
cord-008530-yni0poh9	588	4	important	important	JJ
cord-008530-yni0poh9	588	5	in	in	IN
cord-008530-yni0poh9	588	6	CNS	CNS	NNP
cord-008530-yni0poh9	588	7	defense	defense	NN
cord-008530-yni0poh9	588	8	against	against	IN
cord-008530-yni0poh9	588	9	viral	viral	JJ
cord-008530-yni0poh9	588	10	infection	infection	NN
cord-008530-yni0poh9	588	11	where	where	WRB
cord-008530-yni0poh9	588	12	IP-10	IP-10	NNP
cord-008530-yni0poh9	588	13	is	be	VBZ
cord-008530-yni0poh9	588	14	highly	highly	RB
cord-008530-yni0poh9	588	15	expressed	express	VBN
cord-008530-yni0poh9	588	16	,	,	,
cord-008530-yni0poh9	588	17	and	and	CC
cord-008530-yni0poh9	588	18	whether	whether	IN
cord-008530-yni0poh9	588	19	any	any	DT
cord-008530-yni0poh9	588	20	other	other	JJ
cord-008530-yni0poh9	588	21	chemokines	chemokine	NNS
cord-008530-yni0poh9	588	22	have	have	VBP
cord-008530-yni0poh9	588	23	an	an	DT
cord-008530-yni0poh9	588	24	antiviral	antiviral	JJ
cord-008530-yni0poh9	588	25	function	function	NN
cord-008530-yni0poh9	588	26	,	,	,
cord-008530-yni0poh9	588	27	remain	remain	VBP
cord-008530-yni0poh9	588	28	open	open	JJ
cord-008530-yni0poh9	588	29	questions	question	NNS
cord-008530-yni0poh9	588	30	.	.	.
cord-008530-yni0poh9	589	1	A	a	DT
cord-008530-yni0poh9	589	2	further	further	JJ
cord-008530-yni0poh9	589	3	consequence	consequence	NN
cord-008530-yni0poh9	589	4	of	of	IN
cord-008530-yni0poh9	589	5	the	the	DT
cord-008530-yni0poh9	589	6	localized	localized	JJ
cord-008530-yni0poh9	589	7	production	production	NN
cord-008530-yni0poh9	589	8	of	of	IN
cord-008530-yni0poh9	589	9	chemokines	chemokine	NNS
cord-008530-yni0poh9	589	10	in	in	IN
cord-008530-yni0poh9	589	11	the	the	DT
cord-008530-yni0poh9	589	12	brain	brain	NN
cord-008530-yni0poh9	589	13	is	be	VBZ
cord-008530-yni0poh9	589	14	likely	likely	RB
cord-008530-yni0poh9	589	15	the	the	DT
cord-008530-yni0poh9	589	16	direct	direct	JJ
cord-008530-yni0poh9	589	17	modulation	modulation	NN
cord-008530-yni0poh9	589	18	of	of	IN
cord-008530-yni0poh9	589	19	CNS	CNS	NNP
cord-008530-yni0poh9	589	20	cell	cell	NN
cord-008530-yni0poh9	589	21	function	function	NN
cord-008530-yni0poh9	589	22	.	.	.
cord-008530-yni0poh9	590	1	Various	various	JJ
cord-008530-yni0poh9	590	2	classes	class	NNS
cord-008530-yni0poh9	590	3	of	of	IN
cord-008530-yni0poh9	590	4	chemokine	chemokine	NN
cord-008530-yni0poh9	590	5	receptors	receptor	NNS
cord-008530-yni0poh9	590	6	are	be	VBP
cord-008530-yni0poh9	590	7	expressed	express	VBN
cord-008530-yni0poh9	590	8	by	by	IN
cord-008530-yni0poh9	590	9	CNS	CNS	NNP
cord-008530-yni0poh9	590	10	cells	cell	NNS
cord-008530-yni0poh9	590	11	including	include	VBG
cord-008530-yni0poh9	590	12	neurons	neuron	NNS
cord-008530-yni0poh9	590	13	and	and	CC
cord-008530-yni0poh9	590	14	the	the	DT
cord-008530-yni0poh9	590	15	glia	glia	NN
cord-008530-yni0poh9	590	16	.	.	.
cord-008530-yni0poh9	591	1	In	in	IN
cord-008530-yni0poh9	591	2	many	many	JJ
cord-008530-yni0poh9	591	3	respects	respect	NNS
cord-008530-yni0poh9	591	4	the	the	DT
cord-008530-yni0poh9	591	5	CNS	CNS	NNP
cord-008530-yni0poh9	591	6	possesses	possess	VBZ
cord-008530-yni0poh9	591	7	its	-PRON-	PRP$
cord-008530-yni0poh9	591	8	own	own	JJ
cord-008530-yni0poh9	591	9	chemokine	chemokine	NN
cord-008530-yni0poh9	591	10	network	network	NN
cord-008530-yni0poh9	591	11	permitting	permit	VBG
cord-008530-yni0poh9	591	12	autocrine	autocrine	NN
cord-008530-yni0poh9	591	13	and	and	CC
cord-008530-yni0poh9	591	14	paracrine	paracrine	JJ
cord-008530-yni0poh9	591	15	regulation	regulation	NN
cord-008530-yni0poh9	591	16	of	of	IN
cord-008530-yni0poh9	591	17	cellular	cellular	JJ
cord-008530-yni0poh9	591	18	activity	activity	NN
cord-008530-yni0poh9	591	19	.	.	.
cord-008530-yni0poh9	592	1	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	592	2	are	be	VBP
cord-008530-yni0poh9	592	3	implicated	implicate	VBN
cord-008530-yni0poh9	592	4	in	in	IN
cord-008530-yni0poh9	592	5	many	many	JJ
cord-008530-yni0poh9	592	6	physiological	physiological	JJ
cord-008530-yni0poh9	592	7	functions	function	NNS
cord-008530-yni0poh9	592	8	including	include	VBG
cord-008530-yni0poh9	592	9	development	development	NN
cord-008530-yni0poh9	592	10	,	,	,
cord-008530-yni0poh9	592	11	cell	cell	NN
cord-008530-yni0poh9	592	12	growth	growth	NN
cord-008530-yni0poh9	592	13	,	,	,
cord-008530-yni0poh9	592	14	angiogenesis	angiogenesis	NN
cord-008530-yni0poh9	592	15	,	,	,
cord-008530-yni0poh9	592	16	and	and	CC
cord-008530-yni0poh9	592	17	cellular	cellular	JJ
cord-008530-yni0poh9	592	18	migration	migration	NN
cord-008530-yni0poh9	592	19	.	.	.
cord-008530-yni0poh9	593	1	Perturbation	perturbation	NN
cord-008530-yni0poh9	593	2	of	of	IN
cord-008530-yni0poh9	593	3	the	the	DT
cord-008530-yni0poh9	593	4	CNS	CNS	NNP
cord-008530-yni0poh9	593	5	chemokine	chemokine	NN
cord-008530-yni0poh9	593	6	network	network	NN
cord-008530-yni0poh9	593	7	,	,	,
cord-008530-yni0poh9	593	8	resulting	result	VBG
cord-008530-yni0poh9	593	9	from	from	IN
cord-008530-yni0poh9	593	10	viral	viral	JJ
cord-008530-yni0poh9	593	11	infection	infection	NN
cord-008530-yni0poh9	593	12	,	,	,
cord-008530-yni0poh9	593	13	could	could	MD
cord-008530-yni0poh9	593	14	therefore	therefore	RB
cord-008530-yni0poh9	593	15	either	either	RB
cord-008530-yni0poh9	593	16	be	be	VB
cord-008530-yni0poh9	593	17	beneficial	beneficial	JJ
cord-008530-yni0poh9	593	18	by	by	IN
cord-008530-yni0poh9	593	19	promoting	promote	VBG
cord-008530-yni0poh9	593	20	reparative	reparative	JJ
cord-008530-yni0poh9	593	21	processes	process	NNS
cord-008530-yni0poh9	593	22	or	or	CC
cord-008530-yni0poh9	593	23	detrimental	detrimental	JJ
cord-008530-yni0poh9	593	24	by	by	IN
cord-008530-yni0poh9	593	25	contributing	contribute	VBG
cord-008530-yni0poh9	593	26	to	to	IN
cord-008530-yni0poh9	593	27	tissue	tissue	NN
cord-008530-yni0poh9	593	28	injury	injury	NN
cord-008530-yni0poh9	593	29	and	and	CC
cord-008530-yni0poh9	593	30	loss	loss	NN
cord-008530-yni0poh9	593	31	.	.	.
cord-008530-yni0poh9	594	1	In	in	IN
cord-008530-yni0poh9	594	2	conclusion	conclusion	NN
cord-008530-yni0poh9	594	3	,	,	,
cord-008530-yni0poh9	594	4	it	-PRON-	PRP
cord-008530-yni0poh9	594	5	is	be	VBZ
cord-008530-yni0poh9	594	6	now	now	RB
cord-008530-yni0poh9	594	7	apparent	apparent	JJ
cord-008530-yni0poh9	594	8	that	that	IN
cord-008530-yni0poh9	594	9	,	,	,
cord-008530-yni0poh9	594	10	like	like	IN
cord-008530-yni0poh9	594	11	their	-PRON-	PRP$
cord-008530-yni0poh9	594	12	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	594	13	cytokine	cytokine	NN
cord-008530-yni0poh9	594	14	counterparts	counterpart	NNS
cord-008530-yni0poh9	594	15	,	,	,
cord-008530-yni0poh9	594	16	the	the	DT
cord-008530-yni0poh9	594	17	chemokines	chemokine	NNS
cord-008530-yni0poh9	594	18	are	be	VBP
cord-008530-yni0poh9	594	19	important	important	JJ
cord-008530-yni0poh9	594	20	plurifunctional	plurifunctional	JJ
cord-008530-yni0poh9	594	21	mediators	mediator	NNS
cord-008530-yni0poh9	594	22	in	in	IN
cord-008530-yni0poh9	594	23	the	the	DT
cord-008530-yni0poh9	594	24	host	host	NN
cord-008530-yni0poh9	594	25	response	response	NN
cord-008530-yni0poh9	594	26	to	to	IN
cord-008530-yni0poh9	594	27	viral	viral	JJ
cord-008530-yni0poh9	594	28	infection	infection	NN
cord-008530-yni0poh9	594	29	of	of	IN
cord-008530-yni0poh9	594	30	the	the	DT
cord-008530-yni0poh9	594	31	CNS	CNS	NNP
cord-008530-yni0poh9	594	32	(	(	-LRB-
cord-008530-yni0poh9	594	33	see	see	VB
cord-008530-yni0poh9	594	34	Fig	Fig	NNP
cord-008530-yni0poh9	594	35	.	.	.
cord-008530-yni0poh9	595	1	3	3	CD
cord-008530-yni0poh9	595	2	and	and	CC
cord-008530-yni0poh9	595	3	color	color	NN
cord-008530-yni0poh9	595	4	section	section	NN
cord-008530-yni0poh9	595	5	)	)	-RRB-
cord-008530-yni0poh9	595	6	.	.	.
cord-008530-yni0poh9	596	1	As	as	IN
cord-008530-yni0poh9	596	2	such	such	JJ
cord-008530-yni0poh9	596	3	,	,	,
cord-008530-yni0poh9	596	4	a	a	DT
cord-008530-yni0poh9	596	5	greater	great	JJR
cord-008530-yni0poh9	596	6	understanding	understanding	NN
cord-008530-yni0poh9	596	7	of	of	IN
cord-008530-yni0poh9	596	8	the	the	DT
cord-008530-yni0poh9	596	9	neurocellular	neurocellular	JJ
cord-008530-yni0poh9	596	10	and	and	CC
cord-008530-yni0poh9	596	11	viral	viral	JJ
cord-008530-yni0poh9	596	12	targets	target	NNS
cord-008530-yni0poh9	596	13	and	and	CC
cord-008530-yni0poh9	596	14	functions	function	NNS
cord-008530-yni0poh9	596	15	of	of	IN
cord-008530-yni0poh9	596	16	the	the	DT
cord-008530-yni0poh9	596	17	chemokines	chemokine	NNS
cord-008530-yni0poh9	596	18	holds	hold	VBZ
cord-008530-yni0poh9	596	19	the	the	DT
cord-008530-yni0poh9	596	20	promise	promise	NN
cord-008530-yni0poh9	596	21	of	of	IN
cord-008530-yni0poh9	596	22	revealing	reveal	VBG
cord-008530-yni0poh9	596	23	new	new	JJ
cord-008530-yni0poh9	596	24	molecular	molecular	JJ
cord-008530-yni0poh9	596	25	focal	focal	JJ
cord-008530-yni0poh9	596	26	points	point	NNS
cord-008530-yni0poh9	596	27	for	for	IN
cord-008530-yni0poh9	596	28	therapeutic	therapeutic	JJ
cord-008530-yni0poh9	596	29	inter-	inter-	NN
cord-008530-yni0poh9	597	1	[	[	-LRB-
cord-008530-yni0poh9	597	2	For	for	IN
cord-008530-yni0poh9	597	3	color	color	NN
cord-008530-yni0poh9	597	4	reproduction	reproduction	NN
cord-008530-yni0poh9	597	5	,	,	,
cord-008530-yni0poh9	597	6	see	see	VB
cord-008530-yni0poh9	597	7	color	color	NN
cord-008530-yni0poh9	597	8	section	section	NN
cord-008530-yni0poh9	597	9	.	.	.
cord-008530-yni0poh9	597	10	]	]	-RRB-
cord-008530-yni0poh9	598	1	Chemokines	chemokine	NNS
cord-008530-yni0poh9	598	2	are	be	VBP
cord-008530-yni0poh9	598	3	potentially	potentially	RB
cord-008530-yni0poh9	598	4	multifunctional	multifunctional	JJ
cord-008530-yni0poh9	598	5	effectors	effector	NNS
cord-008530-yni0poh9	598	6	in	in	IN
cord-008530-yni0poh9	598	7	CNS	CNS	NNP
cord-008530-yni0poh9	598	8	viral	viral	JJ
cord-008530-yni0poh9	598	9	infections	infection	NNS
cord-008530-yni0poh9	598	10	.	.	.
cord-008530-yni0poh9	599	1	In	in	IN
cord-008530-yni0poh9	599	2	this	this	DT
cord-008530-yni0poh9	599	3	schema	schema	NN
cord-008530-yni0poh9	599	4	,	,	,
cord-008530-yni0poh9	599	5	initial	initial	JJ
cord-008530-yni0poh9	599	6	infection	infection	NN
cord-008530-yni0poh9	599	7	of	of	IN
cord-008530-yni0poh9	599	8	the	the	DT
cord-008530-yni0poh9	599	9	CNS	CNS	NNP
cord-008530-yni0poh9	599	10	with	with	IN
cord-008530-yni0poh9	599	11	a	a	DT
cord-008530-yni0poh9	599	12	virus	virus	NN
cord-008530-yni0poh9	599	13	results	result	VBZ
cord-008530-yni0poh9	599	14	in	in	IN
cord-008530-yni0poh9	599	15	the	the	DT
cord-008530-yni0poh9	599	16	localized	localized	JJ
cord-008530-yni0poh9	599	17	production	production	NN
cord-008530-yni0poh9	599	18	of	of	IN
cord-008530-yni0poh9	599	19	chemokines	chemokine	NNS
cord-008530-yni0poh9	599	20	by	by	IN
cord-008530-yni0poh9	599	21	reactive	reactive	JJ
cord-008530-yni0poh9	599	22	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	599	23	and	and	CC
cord-008530-yni0poh9	599	24	microglia	microglia	NNS
cord-008530-yni0poh9	599	25	.	.	.
cord-008530-yni0poh9	600	1	Some	some	DT
cord-008530-yni0poh9	600	2	chemokines	chemokine	NNS
cord-008530-yni0poh9	600	3	such	such	JJ
cord-008530-yni0poh9	600	4	as	as	IN
cord-008530-yni0poh9	600	5	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	600	6	and	and	CC
cord-008530-yni0poh9	600	7	fractalkine	fractalkine	NN
cord-008530-yni0poh9	600	8	are	be	VBP
cord-008530-yni0poh9	600	9	produced	produce	VBN
cord-008530-yni0poh9	600	10	constitutively	constitutively	RB
cord-008530-yni0poh9	600	11	in	in	IN
cord-008530-yni0poh9	600	12	the	the	DT
cord-008530-yni0poh9	600	13	CNS	CNS	NNP
cord-008530-yni0poh9	600	14	and	and	CC
cord-008530-yni0poh9	600	15	their	-PRON-	PRP$
cord-008530-yni0poh9	600	16	production	production	NN
cord-008530-yni0poh9	600	17	may	may	MD
cord-008530-yni0poh9	600	18	also	also	RB
cord-008530-yni0poh9	600	19	be	be	VB
cord-008530-yni0poh9	600	20	altered	alter	VBN
cord-008530-yni0poh9	600	21	by	by	IN
cord-008530-yni0poh9	600	22	viral	viral	JJ
cord-008530-yni0poh9	600	23	infection	infection	NN
cord-008530-yni0poh9	600	24	.	.	.
cord-008530-yni0poh9	601	1	Increased	increase	VBN
cord-008530-yni0poh9	601	2	chemokine	chemokine	NN
cord-008530-yni0poh9	601	3	production	production	NN
cord-008530-yni0poh9	601	4	may	may	MD
cord-008530-yni0poh9	601	5	then	then	RB
cord-008530-yni0poh9	601	6	promote	promote	VB
cord-008530-yni0poh9	601	7	the	the	DT
cord-008530-yni0poh9	601	8	further	further	JJ
cord-008530-yni0poh9	601	9	recruitment	recruitment	NN
cord-008530-yni0poh9	601	10	and	and	CC
cord-008530-yni0poh9	601	11	extravasation	extravasation	NN
cord-008530-yni0poh9	601	12	of	of	IN
cord-008530-yni0poh9	601	13	antiviral	antiviral	JJ
cord-008530-yni0poh9	601	14	immune	immune	JJ
cord-008530-yni0poh9	601	15	effector	effector	NN
cord-008530-yni0poh9	601	16	cells	cell	NNS
cord-008530-yni0poh9	601	17	from	from	IN
cord-008530-yni0poh9	601	18	the	the	DT
cord-008530-yni0poh9	601	19	periphery	periphery	NN
cord-008530-yni0poh9	601	20	.	.	.
cord-008530-yni0poh9	602	1	Chemokine	chemokine	JJ
cord-008530-yni0poh9	602	2	receptors	receptor	NNS
cord-008530-yni0poh9	602	3	are	be	VBP
cord-008530-yni0poh9	602	4	widely	widely	RB
cord-008530-yni0poh9	602	5	expressed	express	VBN
cord-008530-yni0poh9	602	6	by	by	IN
cord-008530-yni0poh9	602	7	neuronal	neuronal	JJ
cord-008530-yni0poh9	602	8	and	and	CC
cord-008530-yni0poh9	602	9	glial	glial	JJ
cord-008530-yni0poh9	602	10	cells	cell	NNS
cord-008530-yni0poh9	602	11	and	and	CC
cord-008530-yni0poh9	602	12	additional	additional	JJ
cord-008530-yni0poh9	602	13	functions	function	NNS
cord-008530-yni0poh9	602	14	of	of	IN
cord-008530-yni0poh9	602	15	the	the	DT
cord-008530-yni0poh9	602	16	chemokines	chemokine	NNS
cord-008530-yni0poh9	602	17	are	be	VBP
cord-008530-yni0poh9	602	18	likely	likely	JJ
cord-008530-yni0poh9	602	19	.	.	.
cord-008530-yni0poh9	603	1	These	these	DT
cord-008530-yni0poh9	603	2	may	may	MD
cord-008530-yni0poh9	603	3	include	include	VB
cord-008530-yni0poh9	603	4	direct	direct	JJ
cord-008530-yni0poh9	603	5	antiviral	antiviral	JJ
cord-008530-yni0poh9	603	6	actions	action	NNS
cord-008530-yni0poh9	603	7	(	(	-LRB-
cord-008530-yni0poh9	603	8	for	for	IN
cord-008530-yni0poh9	603	9	example	example	NN
cord-008530-yni0poh9	603	10	,	,	,
cord-008530-yni0poh9	603	11	by	by	IN
cord-008530-yni0poh9	603	12	IP-10	IP-10	NNP
cord-008530-yni0poh9	603	13	)	)	-RRB-
cord-008530-yni0poh9	603	14	,	,	,
cord-008530-yni0poh9	603	15	and	and	CC
cord-008530-yni0poh9	603	16	intercellular	intercellular	JJ
cord-008530-yni0poh9	603	17	communication	communication	NN
cord-008530-yni0poh9	603	18	(	(	-LRB-
cord-008530-yni0poh9	603	19	for	for	IN
cord-008530-yni0poh9	603	20	example	example	NN
cord-008530-yni0poh9	603	21	,	,	,
cord-008530-yni0poh9	603	22	neuronally	neuronally	RB
cord-008530-yni0poh9	603	23	derived	derive	VBN
cord-008530-yni0poh9	603	24	fractalkine	fractalkine	NN
cord-008530-yni0poh9	603	25	can	can	MD
cord-008530-yni0poh9	603	26	stimulate	stimulate	VB
cord-008530-yni0poh9	603	27	microglia	microglia	NNS
cord-008530-yni0poh9	603	28	)	)	-RRB-
cord-008530-yni0poh9	603	29	.	.	.
cord-008530-yni0poh9	604	1	In	in	IN
cord-008530-yni0poh9	604	2	addition	addition	NN
cord-008530-yni0poh9	604	3	,	,	,
cord-008530-yni0poh9	604	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	604	5	may	may	MD
cord-008530-yni0poh9	604	6	exert	exert	VB
cord-008530-yni0poh9	604	7	detrimental	detrimental	JJ
cord-008530-yni0poh9	604	8	actions	action	NNS
cord-008530-yni0poh9	604	9	;	;	:
cord-008530-yni0poh9	604	10	for	for	IN
cord-008530-yni0poh9	604	11	example	example	NN
cord-008530-yni0poh9	604	12	,	,	,
cord-008530-yni0poh9	604	13	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	604	14	can	can	MD
cord-008530-yni0poh9	604	15	impair	impair	VB
cord-008530-yni0poh9	604	16	neuronal	neuronal	JJ
cord-008530-yni0poh9	604	17	activity	activity	NN
cord-008530-yni0poh9	604	18	and	and	CC
cord-008530-yni0poh9	604	19	stimulate	stimulate	VB
cord-008530-yni0poh9	604	20	apoptosis	apoptosis	NN
cord-008530-yni0poh9	604	21	of	of	IN
cord-008530-yni0poh9	604	22	these	these	DT
cord-008530-yni0poh9	604	23	cells	cell	NNS
cord-008530-yni0poh9	604	24	.	.	.
cord-008530-yni0poh9	605	1	M	M	NNP
cord-008530-yni0poh9	605	2	,	,	,
cord-008530-yni0poh9	605	3	macrophage	macrophage	NN
cord-008530-yni0poh9	605	4	;	;	:
cord-008530-yni0poh9	605	5	Tc	Tc	NNP
cord-008530-yni0poh9	605	6	,	,	,
cord-008530-yni0poh9	605	7	T	T	NNP
cord-008530-yni0poh9	605	8	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	605	9	;	;	:
cord-008530-yni0poh9	605	10	N	n	CD
cord-008530-yni0poh9	605	11	,	,	,
cord-008530-yni0poh9	605	12	neutrophil	neutrophil	NN
cord-008530-yni0poh9	605	13	.	.	.
cord-008530-yni0poh9	606	1	vention	vention	NN
cord-008530-yni0poh9	606	2	that	that	WDT
cord-008530-yni0poh9	606	3	could	could	MD
cord-008530-yni0poh9	606	4	more	more	RBR
cord-008530-yni0poh9	606	5	effectively	effectively	RB
cord-008530-yni0poh9	606	6	control	control	VB
cord-008530-yni0poh9	606	7	CNS	CNS	NNP
cord-008530-yni0poh9	606	8	viral	viral	JJ
cord-008530-yni0poh9	606	9	infections	infection	NNS
cord-008530-yni0poh9	606	10	and	and	CC
cord-008530-yni0poh9	606	11	prevent	prevent	VB
cord-008530-yni0poh9	606	12	tissue	tissue	NN
cord-008530-yni0poh9	606	13	injury	injury	NN
cord-008530-yni0poh9	606	14	.	.	.
cord-008530-yni0poh9	607	1	ACKNOWLEDGMENTS	acknowledgment	NNS
cord-008530-yni0poh9	607	2	Val6rie	Val6rie	NNP
cord-008530-yni0poh9	607	3	Asensio	Asensio	NNP
cord-008530-yni0poh9	607	4	is	be	VBZ
cord-008530-yni0poh9	607	5	a	a	DT
cord-008530-yni0poh9	607	6	postdoctoral	postdoctoral	JJ
cord-008530-yni0poh9	607	7	fellow	fellow	NN
cord-008530-yni0poh9	607	8	of	of	IN
cord-008530-yni0poh9	607	9	the	the	DT
cord-008530-yni0poh9	607	10	National	National	NNP
cord-008530-yni0poh9	607	11	Multiple	Multiple	NNP
cord-008530-yni0poh9	607	12	Sclerosis	Sclerosis	NNP
cord-008530-yni0poh9	607	13	Society	Society	NNP
cord-008530-yni0poh9	607	14	.	.	.
cord-008530-yni0poh9	608	1	The	the	DT
cord-008530-yni0poh9	608	2	authors	author	NNS
cord-008530-yni0poh9	608	3	'	'	POS
cord-008530-yni0poh9	608	4	studies	study	NNS
cord-008530-yni0poh9	608	5	were	be	VBD
cord-008530-yni0poh9	608	6	supported	support	VBN
cord-008530-yni0poh9	608	7	by	by	IN
cord-008530-yni0poh9	608	8	NIH	NIH	NNP
cord-008530-yni0poh9	608	9	grants	grant	NNS
cord-008530-yni0poh9	608	10	MH	MH	NNP
cord-008530-yni0poh9	608	11	50426	50426	CD
cord-008530-yni0poh9	608	12	;	;	:
cord-008530-yni0poh9	608	13	MH	MH	NNP
cord-008530-yni0poh9	608	14	47680	47680	CD
cord-008530-yni0poh9	608	15	and	and	CC
cord-008530-yni0poh9	608	16	NS	NS	NNP
cord-008530-yni0poh9	608	17	36979	36979	CD
cord-008530-yni0poh9	608	18	to	to	IN
cord-008530-yni0poh9	608	19	ILC	ILC	NNP
cord-008530-yni0poh9	608	20	.	.	.
cord-008530-yni0poh9	609	1	This	this	DT
cord-008530-yni0poh9	609	2	chapter	chapter	NN
cord-008530-yni0poh9	609	3	is	be	VBZ
cord-008530-yni0poh9	609	4	publication	publication	NN
cord-008530-yni0poh9	610	1	No	no	UH
cord-008530-yni0poh9	610	2	.	.	.
cord-008530-yni0poh9	611	1	13255-NP	13255-np	CD
cord-008530-yni0poh9	611	2	,	,	,
cord-008530-yni0poh9	611	3	from	from	IN
cord-008530-yni0poh9	611	4	the	the	DT
cord-008530-yni0poh9	611	5	Scripps	Scripps	NNP
cord-008530-yni0poh9	611	6	Research	Research	NNP
cord-008530-yni0poh9	611	7	Institute	Institute	NNP
cord-008530-yni0poh9	611	8	.	.	.
cord-008530-yni0poh9	612	1	Neuronal	neuronal	JJ
cord-008530-yni0poh9	612	2	apoptosis	apoptosis	NN
cord-008530-yni0poh9	612	3	in	in	IN
cord-008530-yni0poh9	612	4	HIV	HIV	NNP
cord-008530-yni0poh9	612	5	infection	infection	NN
cord-008530-yni0poh9	612	6	in	in	IN
cord-008530-yni0poh9	612	7	adults	adult	NNS
cord-008530-yni0poh9	612	8	Chemokine	chemokine	JJ
cord-008530-yni0poh9	612	9	receptors	receptor	NNS
cord-008530-yni0poh9	612	10	and	and	CC
cord-008530-yni0poh9	612	11	molecular	molecular	JJ
cord-008530-yni0poh9	612	12	mimicry	mimicry	NN
cord-008530-yni0poh9	613	1	Molecular	molecular	JJ
cord-008530-yni0poh9	613	2	piracy	piracy	NN
cord-008530-yni0poh9	613	3	of	of	IN
cord-008530-yni0poh9	613	4	mammalian	mammalian	JJ
cord-008530-yni0poh9	613	5	interleukin-8	interleukin-8	NNP
cord-008530-yni0poh9	613	6	receptor	receptor	NN
cord-008530-yni0poh9	613	7	type	type	NN
cord-008530-yni0poh9	613	8	B	b	NN
cord-008530-yni0poh9	613	9	by	by	IN
cord-008530-yni0poh9	613	10	herpesvirus	herpesvirus	NN
cord-008530-yni0poh9	613	11	saimiri	saimiri	NNP
cord-008530-yni0poh9	613	12	CC	CC	NNP
cord-008530-yni0poh9	613	13	CKR5	CKR5	NNP
cord-008530-yni0poh9	613	14	:	:	:
cord-008530-yni0poh9	614	1	a	a	DT
cord-008530-yni0poh9	614	2	RANTES	RANTES	NNPS
cord-008530-yni0poh9	614	3	,	,	,
cord-008530-yni0poh9	614	4	MIP	MIP	NNP
cord-008530-yni0poh9	614	5	-	-	HYPH
cord-008530-yni0poh9	614	6	la	la	NNP
cord-008530-yni0poh9	614	7	,	,	,
cord-008530-yni0poh9	614	8	MIP	MIP	NNP
cord-008530-yni0poh9	614	9	-	-	HYPH
cord-008530-yni0poh9	614	10	I~	I~	NNP
cord-008530-yni0poh9	614	11	receptor	receptor	NN
cord-008530-yni0poh9	614	12	as	as	IN
cord-008530-yni0poh9	614	13	a	a	DT
cord-008530-yni0poh9	614	14	fusion	fusion	NN
cord-008530-yni0poh9	614	15	cofactor	cofactor	NN
cord-008530-yni0poh9	614	16	for	for	IN
cord-008530-yni0poh9	614	17	macrophage	macrophage	NN
cord-008530-yni0poh9	614	18	-	-	HYPH
cord-008530-yni0poh9	614	19	Tropic	Tropic	NNP
cord-008530-yni0poh9	614	20	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	614	21	Genes	Genes	NNPS
cord-008530-yni0poh9	614	22	for	for	IN
cord-008530-yni0poh9	614	23	chemokines	chemokine	NNS
cord-008530-yni0poh9	614	24	MuMig	MuMig	NNP
cord-008530-yni0poh9	614	25	and	and	CC
cord-008530-yni0poh9	614	26	Crg-2	Crg-2	NNP
cord-008530-yni0poh9	614	27	induced	induce	VBN
cord-008530-yni0poh9	614	28	in	in	IN
cord-008530-yni0poh9	614	29	protozoan	protozoan	NN
cord-008530-yni0poh9	614	30	and	and	CC
cord-008530-yni0poh9	614	31	viral	viral	JJ
cord-008530-yni0poh9	614	32	infections	infection	NNS
cord-008530-yni0poh9	614	33	in	in	IN
cord-008530-yni0poh9	614	34	response	response	NN
cord-008530-yni0poh9	614	35	to	to	IN
cord-008530-yni0poh9	614	36	IFN-7	IFN-7	NNP
cord-008530-yni0poh9	614	37	with	with	IN
cord-008530-yni0poh9	614	38	patterns	pattern	NNS
cord-008530-yni0poh9	614	39	of	of	IN
cord-008530-yni0poh9	614	40	tissue	tissue	NN
cord-008530-yni0poh9	614	41	expression	expression	NN
cord-008530-yni0poh9	614	42	that	that	WDT
cord-008530-yni0poh9	614	43	suggest	suggest	VBP
cord-008530-yni0poh9	614	44	nonredundant	nonredundant	JJ
cord-008530-yni0poh9	614	45	roles	role	NNS
cord-008530-yni0poh9	614	46	in	in	IN
cord-008530-yni0poh9	614	47	vivo	vivo	NNP
cord-008530-yni0poh9	614	48	Human	Human	NNP
cord-008530-yni0poh9	614	49	T	T	NNP
cord-008530-yni0poh9	614	50	-	-	HYPH
cord-008530-yni0poh9	614	51	cell	cell	NN
cord-008530-yni0poh9	614	52	leukemia	leukemia	NN
cord-008530-yni0poh9	614	53	virus	virus	NN
cord-008530-yni0poh9	614	54	type	type	NN
cord-008530-yni0poh9	614	55	1	1	CD
cord-008530-yni0poh9	614	56	Tax	tax	NN
cord-008530-yni0poh9	614	57	protein	protein	NN
cord-008530-yni0poh9	614	58	induces	induce	VBZ
cord-008530-yni0poh9	614	59	the	the	DT
cord-008530-yni0poh9	614	60	expression	expression	NN
cord-008530-yni0poh9	614	61	of	of	IN
cord-008530-yni0poh9	614	62	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	614	63	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	614	64	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	614	65	/	/	SYM
cord-008530-yni0poh9	614	66	PBSF	PBSF	NNP
cord-008530-yni0poh9	614	67	Human	Human	NNP
cord-008530-yni0poh9	614	68	herpesvirus	herpesvirus	NN
cord-008530-yni0poh9	614	69	KSHV	KSHV	NNP
cord-008530-yni0poh9	614	70	encodes	encode	VBZ
cord-008530-yni0poh9	614	71	a	a	DT
cord-008530-yni0poh9	614	72	constitutively	constitutively	RB
cord-008530-yni0poh9	614	73	active	active	JJ
cord-008530-yni0poh9	614	74	G	g	NN
cord-008530-yni0poh9	614	75	-	-	HYPH
cord-008530-yni0poh9	614	76	protein	protein	NN
cord-008530-yni0poh9	614	77	coupled	couple	VBN
cord-008530-yni0poh9	614	78	receptor	receptor	NN
cord-008530-yni0poh9	614	79	linked	link	VBN
cord-008530-yni0poh9	614	80	to	to	IN
cord-008530-yni0poh9	614	81	cell	cell	NN
cord-008530-yni0poh9	614	82	proliferation	proliferation	NN
cord-008530-yni0poh9	614	83	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	614	84	gene	gene	NN
cord-008530-yni0poh9	614	85	expression	expression	NN
cord-008530-yni0poh9	614	86	in	in	IN
cord-008530-yni0poh9	614	87	the	the	DT
cord-008530-yni0poh9	614	88	brains	brain	NNS
cord-008530-yni0poh9	614	89	of	of	IN
cord-008530-yni0poh9	614	90	mice	mouse	NNS
cord-008530-yni0poh9	614	91	with	with	IN
cord-008530-yni0poh9	614	92	lymphocytic	lymphocytic	JJ
cord-008530-yni0poh9	614	93	choriomeningitis	choriomeningitis	NNP
cord-008530-yni0poh9	614	94	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	614	95	and	and	CC
cord-008530-yni0poh9	614	96	their	-PRON-	PRP$
cord-008530-yni0poh9	614	97	receptors	receptor	NNS
cord-008530-yni0poh9	614	98	in	in	IN
cord-008530-yni0poh9	614	99	the	the	DT
cord-008530-yni0poh9	614	100	CNS	CNS	NNP
cord-008530-yni0poh9	614	101	:	:	:
cord-008530-yni0poh9	614	102	directing	direct	VBG
cord-008530-yni0poh9	614	103	cellular	cellular	JJ
cord-008530-yni0poh9	614	104	communication	communication	NN
cord-008530-yni0poh9	614	105	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	614	106	and	and	CC
cord-008530-yni0poh9	614	107	the	the	DT
cord-008530-yni0poh9	614	108	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	614	109	response	response	NN
cord-008530-yni0poh9	614	110	to	to	IN
cord-008530-yni0poh9	614	111	viral	viral	JJ
cord-008530-yni0poh9	614	112	infection	infection	NN
cord-008530-yni0poh9	614	113	in	in	IN
cord-008530-yni0poh9	614	114	the	the	DT
cord-008530-yni0poh9	614	115	central	central	JJ
cord-008530-yni0poh9	614	116	nervous	nervous	JJ
cord-008530-yni0poh9	614	117	system	system	NN
cord-008530-yni0poh9	614	118	with	with	IN
cord-008530-yni0poh9	614	119	a	a	DT
cord-008530-yni0poh9	614	120	focus	focus	NN
cord-008530-yni0poh9	614	121	on	on	IN
cord-008530-yni0poh9	614	122	lymphocytic	lymphocytic	JJ
cord-008530-yni0poh9	614	123	choriomeningitis	choriomeningitis	NNP
cord-008530-yni0poh9	614	124	virus	virus	NN
cord-008530-yni0poh9	614	125	C10	C10	NNP
cord-008530-yni0poh9	614	126	is	be	VBZ
cord-008530-yni0poh9	614	127	a	a	DT
cord-008530-yni0poh9	614	128	novel	novel	JJ
cord-008530-yni0poh9	614	129	chemokine	chemokine	NN
cord-008530-yni0poh9	614	130	expressed	express	VBN
cord-008530-yni0poh9	614	131	in	in	IN
cord-008530-yni0poh9	614	132	experimental	experimental	JJ
cord-008530-yni0poh9	614	133	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	614	134	demyelinating	demyelinating	JJ
cord-008530-yni0poh9	614	135	disorders	disorder	NNS
cord-008530-yni0poh9	614	136	that	that	WDT
cord-008530-yni0poh9	614	137	promotes	promote	VBZ
cord-008530-yni0poh9	614	138	the	the	DT
cord-008530-yni0poh9	614	139	recruitment	recruitment	NN
cord-008530-yni0poh9	614	140	of	of	IN
cord-008530-yni0poh9	614	141	macrophages	macrophage	NNS
cord-008530-yni0poh9	614	142	to	to	IN
cord-008530-yni0poh9	614	143	the	the	DT
cord-008530-yni0poh9	614	144	central	central	JJ
cord-008530-yni0poh9	614	145	nervous	nervous	JJ
cord-008530-yni0poh9	614	146	system	system	NN
cord-008530-yni0poh9	614	147	Constitutive	constitutive	JJ
cord-008530-yni0poh9	614	148	expression	expression	NN
cord-008530-yni0poh9	614	149	of	of	IN
cord-008530-yni0poh9	614	150	various	various	JJ
cord-008530-yni0poh9	614	151	chemokine	chemokine	NN
cord-008530-yni0poh9	614	152	genes	gene	NNS
cord-008530-yni0poh9	614	153	in	in	IN
cord-008530-yni0poh9	614	154	human	human	JJ
cord-008530-yni0poh9	614	155	T	t	NN
cord-008530-yni0poh9	614	156	-	-	HYPH
cord-008530-yni0poh9	614	157	cell	cell	NN
cord-008530-yni0poh9	614	158	lines	line	NNS
cord-008530-yni0poh9	614	159	infected	infect	VBN
cord-008530-yni0poh9	614	160	with	with	IN
cord-008530-yni0poh9	614	161	human	human	JJ
cord-008530-yni0poh9	614	162	T	t	NN
cord-008530-yni0poh9	614	163	-	-	HYPH
cord-008530-yni0poh9	614	164	cell	cell	NN
cord-008530-yni0poh9	614	165	leukemia	leukemia	NN
cord-008530-yni0poh9	614	166	virus	virus	NN
cord-008530-yni0poh9	614	167	type	type	NN
cord-008530-yni0poh9	614	168	1	1	CD
cord-008530-yni0poh9	614	169	:	:	:
cord-008530-yni0poh9	614	170	role	role	NN
cord-008530-yni0poh9	614	171	of	of	IN
cord-008530-yni0poh9	614	172	the	the	DT
cord-008530-yni0poh9	614	173	viral	viral	JJ
cord-008530-yni0poh9	614	174	transactivator	transactivator	NNP
cord-008530-yni0poh9	614	175	Tax	Tax	NNP
cord-008530-yni0poh9	614	176	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	614	177	in	in	IN
cord-008530-yni0poh9	614	178	disease	disease	NN
cord-008530-yni0poh9	614	179	models	model	NNS
cord-008530-yni0poh9	614	180	and	and	CC
cord-008530-yni0poh9	614	181	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	614	182	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	614	183	and	and	CC
cord-008530-yni0poh9	614	184	leukocyte	leukocyte	NN
cord-008530-yni0poh9	614	185	traffic	traffic	NN
cord-008530-yni0poh9	614	186	Interleukin-8	Interleukin-8	NNP
cord-008530-yni0poh9	614	187	and	and	CC
cord-008530-yni0poh9	614	188	related	related	JJ
cord-008530-yni0poh9	614	189	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	614	190	cytokines	cytokine	NNS
cord-008530-yni0poh9	614	191	-	-	:
cord-008530-yni0poh9	614	192	CXC	CXC	NNP
cord-008530-yni0poh9	614	193	and	and	CC
cord-008530-yni0poh9	614	194	CC	CC	NNP
cord-008530-yni0poh9	614	195	chemokines	chemokine	NNS
cord-008530-yni0poh9	614	196	Human	Human	NNP
cord-008530-yni0poh9	614	197	chemokines	chemokine	NNS
cord-008530-yni0poh9	614	198	:	:	:
cord-008530-yni0poh9	614	199	an	an	DT
cord-008530-yni0poh9	614	200	update	update	NN
cord-008530-yni0poh9	614	201	G	g	NN
cord-008530-yni0poh9	614	202	-	-	HYPH
cord-008530-yni0poh9	614	203	protein	protein	NN
cord-008530-yni0poh9	614	204	-	-	HYPH
cord-008530-yni0poh9	614	205	coupled	couple	VBN
cord-008530-yni0poh9	614	206	receptor	receptor	NN
cord-008530-yni0poh9	614	207	of	of	IN
cord-008530-yni0poh9	614	208	Kaposi	Kaposi	NNP
cord-008530-yni0poh9	614	209	's	's	POS
cord-008530-yni0poh9	614	210	sarcoma	sarcoma	NN
cord-008530-yni0poh9	614	211	-	-	HYPH
cord-008530-yni0poh9	614	212	associated	associate	VBN
cord-008530-yni0poh9	614	213	herpesvirus	herpesvirus	NN
cord-008530-yni0poh9	614	214	is	be	VBZ
cord-008530-yni0poh9	614	215	a	a	DT
cord-008530-yni0poh9	614	216	viral	viral	JJ
cord-008530-yni0poh9	614	217	oncogene	oncogene	NN
cord-008530-yni0poh9	614	218	and	and	CC
cord-008530-yni0poh9	614	219	angiogenesis	angiogenesis	NN
cord-008530-yni0poh9	614	220	activator	activator	NN
cord-008530-yni0poh9	614	221	Expression	expression	NN
cord-008530-yni0poh9	614	222	of	of	IN
cord-008530-yni0poh9	614	223	chemokine	chemokine	NN
cord-008530-yni0poh9	614	224	receptors	receptor	NNS
cord-008530-yni0poh9	614	225	in	in	IN
cord-008530-yni0poh9	614	226	the	the	DT
cord-008530-yni0poh9	614	227	rat	rat	NN
cord-008530-yni0poh9	614	228	brain	brain	NN
cord-008530-yni0poh9	614	229	CCR5(+	CCR5(+	NNP
cord-008530-yni0poh9	614	230	)	)	-RRB-
cord-008530-yni0poh9	614	231	and	and	CC
cord-008530-yni0poh9	614	232	CXCR3(+	cxcr3(+	$
cord-008530-yni0poh9	614	233	)	)	-RRB-
cord-008530-yni0poh9	614	234	T	t	NN
cord-008530-yni0poh9	614	235	cells	cell	NNS
cord-008530-yni0poh9	614	236	are	be	VBP
cord-008530-yni0poh9	614	237	increased	increase	VBN
cord-008530-yni0poh9	614	238	in	in	IN
cord-008530-yni0poh9	614	239	multiple	multiple	JJ
cord-008530-yni0poh9	614	240	sclerosis	sclerosis	NN
cord-008530-yni0poh9	614	241	and	and	CC
cord-008530-yni0poh9	614	242	their	-PRON-	PRP$
cord-008530-yni0poh9	614	243	ligands	ligand	NNS
cord-008530-yni0poh9	614	244	MIP	MIP	NNP
cord-008530-yni0poh9	614	245	-	-	HYPH
cord-008530-yni0poh9	614	246	lalpha	lalpha	NNS
cord-008530-yni0poh9	614	247	and	and	CC
cord-008530-yni0poh9	614	248	IP-10	IP-10	NNP
cord-008530-yni0poh9	614	249	are	be	VBP
cord-008530-yni0poh9	614	250	expressed	express	VBN
cord-008530-yni0poh9	614	251	in	in	IN
cord-008530-yni0poh9	614	252	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	614	253	brain	brain	NN
cord-008530-yni0poh9	614	254	lesions	lesion	NNS
cord-008530-yni0poh9	614	255	A	a	DT
cord-008530-yni0poh9	614	256	new	new	JJ
cord-008530-yni0poh9	614	257	class	class	NN
cord-008530-yni0poh9	614	258	of	of	IN
cord-008530-yni0poh9	614	259	membrane	membrane	NN
cord-008530-yni0poh9	614	260	-	-	HYPH
cord-008530-yni0poh9	614	261	bound	bind	VBN
cord-008530-yni0poh9	614	262	chemokine	chemokine	NN
cord-008530-yni0poh9	614	263	with	with	IN
cord-008530-yni0poh9	614	264	a	a	DT
cord-008530-yni0poh9	614	265	CX3C	CX3C	NNS
cord-008530-yni0poh9	614	266	motif	motif	NN
cord-008530-yni0poh9	614	267	Overriding	override	VBG
cord-008530-yni0poh9	614	268	the	the	DT
cord-008530-yni0poh9	614	269	brain	brain	NN
cord-008530-yni0poh9	614	270	's	's	POS
cord-008530-yni0poh9	614	271	intrinsic	intrinsic	JJ
cord-008530-yni0poh9	614	272	resistance	resistance	NN
cord-008530-yni0poh9	614	273	to	to	IN
cord-008530-yni0poh9	614	274	leukocyte	leukocyte	NN
cord-008530-yni0poh9	614	275	recruitment	recruitment	NN
cord-008530-yni0poh9	614	276	with	with	IN
cord-008530-yni0poh9	614	277	intraparenchymal	intraparenchymal	JJ
cord-008530-yni0poh9	614	278	injections	injection	NNS
cord-008530-yni0poh9	614	279	of	of	IN
cord-008530-yni0poh9	614	280	recombinant	recombinant	JJ
cord-008530-yni0poh9	614	281	chemokines	chemokine	NNS
cord-008530-yni0poh9	614	282	Monocyte	Monocyte	NNP
cord-008530-yni0poh9	614	283	chemotactic	chemotactic	VBD
cord-008530-yni0poh9	614	284	protein-3	protein-3	NNP
cord-008530-yni0poh9	615	1	(	(	-LRB-
cord-008530-yni0poh9	615	2	MCP3	mcp3	NN
cord-008530-yni0poh9	615	3	)	)	-RRB-
cord-008530-yni0poh9	615	4	interacts	interact	VBZ
cord-008530-yni0poh9	615	5	with	with	IN
cord-008530-yni0poh9	615	6	multiple	multiple	JJ
cord-008530-yni0poh9	615	7	leukocyte	leukocyte	NN
cord-008530-yni0poh9	615	8	receptors	receptor	NNS
cord-008530-yni0poh9	615	9	.	.	.
cord-008530-yni0poh9	616	1	C	C	NNP
cord-008530-yni0poh9	616	2	-	-	HYPH
cord-008530-yni0poh9	616	3	C	C	NNP
cord-008530-yni0poh9	616	4	CKR1	CKR1	NNP
cord-008530-yni0poh9	616	5	,	,	,
cord-008530-yni0poh9	616	6	a	a	DT
cord-008530-yni0poh9	616	7	receptor	receptor	NN
cord-008530-yni0poh9	616	8	for	for	IN
cord-008530-yni0poh9	616	9	macrophage	macrophage	NN
cord-008530-yni0poh9	616	10	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	616	11	protein-1	protein-1	NNP
cord-008530-yni0poh9	616	12	alpha	alpha	NN
cord-008530-yni0poh9	616	13	/	/	SYM
cord-008530-yni0poh9	616	14	Rantes	Rantes	NNPS
cord-008530-yni0poh9	616	15	,	,	,
cord-008530-yni0poh9	616	16	is	be	VBZ
cord-008530-yni0poh9	616	17	also	also	RB
cord-008530-yni0poh9	616	18	a	a	DT
cord-008530-yni0poh9	616	19	functional	functional	JJ
cord-008530-yni0poh9	616	20	receptor	receptor	NN
cord-008530-yni0poh9	616	21	for	for	IN
cord-008530-yni0poh9	616	22	MCP3	MCP3	NNP
cord-008530-yni0poh9	616	23	Identification	Identification	NNP
cord-008530-yni0poh9	616	24	of	of	IN
cord-008530-yni0poh9	616	25	the	the	DT
cord-008530-yni0poh9	616	26	CC	CC	NNP
cord-008530-yni0poh9	616	27	chemokines	chemokine	NNS
cord-008530-yni0poh9	616	28	TARC	TARC	NNP
cord-008530-yni0poh9	616	29	and	and	CC
cord-008530-yni0poh9	616	30	macrophage	macrophage	NN
cord-008530-yni0poh9	616	31	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	616	32	protein-1	protein-1	NNP
cord-008530-yni0poh9	616	33	beta	beta	NN
cord-008530-yni0poh9	616	34	as	as	IN
cord-008530-yni0poh9	616	35	novel	novel	JJ
cord-008530-yni0poh9	616	36	functional	functional	JJ
cord-008530-yni0poh9	616	37	ligands	ligand	NNS
cord-008530-yni0poh9	616	38	for	for	IN
cord-008530-yni0poh9	616	39	the	the	DT
cord-008530-yni0poh9	616	40	CCR8	CCR8	NNP
cord-008530-yni0poh9	616	41	receptor	receptor	NN
cord-008530-yni0poh9	616	42	Human	Human	NNP
cord-008530-yni0poh9	616	43	T	T	NNP
cord-008530-yni0poh9	616	44	cell	cell	NN
cord-008530-yni0poh9	616	45	leukemia	leukemia	NN
cord-008530-yni0poh9	616	46	virus	virus	NN
cord-008530-yni0poh9	616	47	type	type	NN
cord-008530-yni0poh9	617	1	I	-PRON-	PRP
cord-008530-yni0poh9	617	2	(	(	-LRB-
cord-008530-yni0poh9	617	3	HTLV	HTLV	NNP
cord-008530-yni0poh9	617	4	-	-	HYPH
cord-008530-yni0poh9	617	5	I)-specific	I)-specific	NNP
cord-008530-yni0poh9	617	6	CD8	CD8	NNP
cord-008530-yni0poh9	617	7	+	+	SYM
cord-008530-yni0poh9	617	8	CTL	CTL	NNP
cord-008530-yni0poh9	617	9	clones	clone	NNS
cord-008530-yni0poh9	617	10	from	from	IN
cord-008530-yni0poh9	617	11	patients	patient	NNS
cord-008530-yni0poh9	617	12	with	with	IN
cord-008530-yni0poh9	617	13	HTLV	HTLV	NNP
cord-008530-yni0poh9	617	14	-	-	HYPH
cord-008530-yni0poh9	617	15	I	i	NN
cord-008530-yni0poh9	617	16	-	-	HYPH
cord-008530-yni0poh9	617	17	associated	associate	VBN
cord-008530-yni0poh9	617	18	neurologic	neurologic	JJ
cord-008530-yni0poh9	617	19	disease	disease	NN
cord-008530-yni0poh9	617	20	secrete	secrete	JJ
cord-008530-yni0poh9	617	21	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	617	22	cytokines	cytokine	NNS
cord-008530-yni0poh9	617	23	,	,	,
cord-008530-yni0poh9	617	24	chemokines	chemokine	NNS
cord-008530-yni0poh9	617	25	,	,	,
cord-008530-yni0poh9	617	26	and	and	CC
cord-008530-yni0poh9	617	27	matrix	matrix	NN
cord-008530-yni0poh9	617	28	metalloproteinase	metalloproteinase	NN
cord-008530-yni0poh9	617	29	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	617	30	infection	infection	NN
cord-008530-yni0poh9	617	31	in	in	IN
cord-008530-yni0poh9	617	32	an	an	DT
cord-008530-yni0poh9	617	33	individual	individual	JJ
cord-008530-yni0poh9	617	34	homozygous	homozygous	JJ
cord-008530-yni0poh9	617	35	for	for	IN
cord-008530-yni0poh9	617	36	the	the	DT
cord-008530-yni0poh9	617	37	CCR5	CCR5	NNP
cord-008530-yni0poh9	617	38	deletion	deletion	NN
cord-008530-yni0poh9	617	39	allele	allele	NN
cord-008530-yni0poh9	618	1	The	the	DT
cord-008530-yni0poh9	618	2	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	618	3	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	618	4	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	618	5	is	be	VBZ
cord-008530-yni0poh9	618	6	a	a	DT
cord-008530-yni0poh9	618	7	ligand	ligand	NN
cord-008530-yni0poh9	618	8	tbr	tbr	NNP
cord-008530-yni0poh9	618	9	LESTR	LESTR	NNP
cord-008530-yni0poh9	618	10	/	/	SYM
cord-008530-yni0poh9	618	11	fusin	fusin	NNP
cord-008530-yni0poh9	618	12	and	and	CC
cord-008530-yni0poh9	618	13	blocks	block	VBZ
cord-008530-yni0poh9	618	14	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	618	15	entry	entry	NN
cord-008530-yni0poh9	619	1	The	the	DT
cord-008530-yni0poh9	619	2	HIV	HIV	NNP
cord-008530-yni0poh9	619	3	coreceptors	coreceptor	NNS
cord-008530-yni0poh9	619	4	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	619	5	and	and	CC
cord-008530-yni0poh9	619	6	CCR5	CCR5	NNP
cord-008530-yni0poh9	619	7	are	be	VBP
cord-008530-yni0poh9	619	8	differentially	differentially	RB
cord-008530-yni0poh9	619	9	expressed	express	VBN
cord-008530-yni0poh9	619	10	and	and	CC
cord-008530-yni0poh9	619	11	regulated	regulate	VBN
cord-008530-yni0poh9	619	12	on	on	IN
cord-008530-yni0poh9	619	13	human	human	JJ
cord-008530-yni0poh9	619	14	T	t	NN
cord-008530-yni0poh9	619	15	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	619	16	Chemokine	chemokine	JJ
cord-008530-yni0poh9	619	17	sequestration	sequestration	NN
cord-008530-yni0poh9	619	18	by	by	IN
cord-008530-yni0poh9	619	19	viral	viral	JJ
cord-008530-yni0poh9	619	20	chemoreceptors	chemoreceptor	NNS
cord-008530-yni0poh9	619	21	as	as	IN
cord-008530-yni0poh9	619	22	a	a	DT
cord-008530-yni0poh9	619	23	novel	novel	JJ
cord-008530-yni0poh9	619	24	viral	viral	JJ
cord-008530-yni0poh9	619	25	escape	escape	NN
cord-008530-yni0poh9	619	26	strategy	strategy	NN
cord-008530-yni0poh9	619	27	:	:	:
cord-008530-yni0poh9	619	28	withdrawal	withdrawal	NN
cord-008530-yni0poh9	619	29	of	of	IN
cord-008530-yni0poh9	619	30	chemokines	chemokine	NNS
cord-008530-yni0poh9	619	31	from	from	IN
cord-008530-yni0poh9	619	32	the	the	DT
cord-008530-yni0poh9	619	33	environment	environment	NN
cord-008530-yni0poh9	619	34	of	of	IN
cord-008530-yni0poh9	619	35	cytomegalovirus	cytomegalovirus	NN
cord-008530-yni0poh9	619	36	-	-	HYPH
cord-008530-yni0poh9	619	37	infected	infect	VBN
cord-008530-yni0poh9	619	38	cells	cell	NNS
cord-008530-yni0poh9	620	1	Cultured	cultured	JJ
cord-008530-yni0poh9	620	2	rat	rat	NN
cord-008530-yni0poh9	620	3	microglia	microglia	NN
cord-008530-yni0poh9	620	4	express	express	VBP
cord-008530-yni0poh9	620	5	functional	functional	JJ
cord-008530-yni0poh9	620	6	beta	beta	JJ
cord-008530-yni0poh9	620	7	-	-	HYPH
cord-008530-yni0poh9	620	8	chemokine	chemokine	NN
cord-008530-yni0poh9	620	9	receptors	receptor	NNS
cord-008530-yni0poh9	620	10	Differential	differential	JJ
cord-008530-yni0poh9	620	11	expression	expression	NN
cord-008530-yni0poh9	620	12	of	of	IN
cord-008530-yni0poh9	620	13	chemokine	chemokine	NN
cord-008530-yni0poh9	620	14	receptors	receptor	NNS
cord-008530-yni0poh9	620	15	and	and	CC
cord-008530-yni0poh9	620	16	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	620	17	responsiveness	responsiveness	NN
cord-008530-yni0poh9	620	18	of	of	IN
cord-008530-yni0poh9	620	19	type	type	NN
cord-008530-yni0poh9	620	20	1	1	CD
cord-008530-yni0poh9	620	21	T	t	NN
cord-008530-yni0poh9	620	22	helper	helper	NN
cord-008530-yni0poh9	620	23	cells	cell	NNS
cord-008530-yni0poh9	620	24	(	(	-LRB-
cord-008530-yni0poh9	620	25	Thls	Thls	NNP
cord-008530-yni0poh9	620	26	)	)	-RRB-
cord-008530-yni0poh9	620	27	and	and	CC
cord-008530-yni0poh9	620	28	Th2s	th2s	NN
cord-008530-yni0poh9	620	29	Upregulation	Upregulation	NNP
cord-008530-yni0poh9	620	30	of	of	IN
cord-008530-yni0poh9	620	31	CCR1	CCR1	NNP
cord-008530-yni0poh9	620	32	and	and	CC
cord-008530-yni0poh9	620	33	CCR3	CCR3	NNP
cord-008530-yni0poh9	620	34	and	and	CC
cord-008530-yni0poh9	620	35	induction	induction	NN
cord-008530-yni0poh9	620	36	of	of	IN
cord-008530-yni0poh9	620	37	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	620	38	to	to	IN
cord-008530-yni0poh9	620	39	CC	cc	NN
cord-008530-yni0poh9	620	40	chemokines	chemokine	NNS
cord-008530-yni0poh9	620	41	by	by	IN
cord-008530-yni0poh9	620	42	IFNgamma	IFNgamma	NNP
cord-008530-yni0poh9	620	43	in	in	IN
cord-008530-yni0poh9	620	44	human	human	JJ
cord-008530-yni0poh9	620	45	neutrophils	neutrophil	NNS
cord-008530-yni0poh9	621	1	Decreased	decrease	VBN
cord-008530-yni0poh9	621	2	lesion	lesion	NN
cord-008530-yni0poh9	621	3	formation	formation	NN
cord-008530-yni0poh9	621	4	in	in	IN
cord-008530-yni0poh9	621	5	CCR2-/-mice	CCR2-/-mice	NNP
cord-008530-yni0poh9	621	6	reveals	reveal	VBZ
cord-008530-yni0poh9	621	7	a	a	DT
cord-008530-yni0poh9	621	8	role	role	NN
cord-008530-yni0poh9	621	9	for	for	IN
cord-008530-yni0poh9	621	10	chemokines	chemokine	NNS
cord-008530-yni0poh9	621	11	in	in	IN
cord-008530-yni0poh9	621	12	the	the	DT
cord-008530-yni0poh9	621	13	initiation	initiation	NN
cord-008530-yni0poh9	621	14	of	of	IN
cord-008530-yni0poh9	621	15	atherosclerosis	atherosclerosis	NN
cord-008530-yni0poh9	621	16	Angiogenic	Angiogenic	NNP
cord-008530-yni0poh9	621	17	and	and	CC
cord-008530-yni0poh9	621	18	HIV	HIV	NNP
cord-008530-yni0poh9	621	19	-	-	HYPH
cord-008530-yni0poh9	621	20	inhibitory	inhibitory	JJ
cord-008530-yni0poh9	621	21	functions	function	NNS
cord-008530-yni0poh9	621	22	of	of	IN
cord-008530-yni0poh9	621	23	KSHV	KSHV	NNP
cord-008530-yni0poh9	621	24	-	-	HYPH
cord-008530-yni0poh9	621	25	encoded	encode	VBN
cord-008530-yni0poh9	621	26	chemokines	chemokine	NNS
cord-008530-yni0poh9	621	27	Involvement	Involvement	NNP
cord-008530-yni0poh9	621	28	of	of	IN
cord-008530-yni0poh9	621	29	interleukin	interleukin	NN
cord-008530-yni0poh9	621	30	(	(	-LRB-
cord-008530-yni0poh9	621	31	IL	IL	NNP
cord-008530-yni0poh9	621	32	)	)	-RRB-
cord-008530-yni0poh9	622	1	8	8	CD
cord-008530-yni0poh9	622	2	receptor	receptor	NN
cord-008530-yni0poh9	622	3	in	in	IN
cord-008530-yni0poh9	622	4	negative	negative	JJ
cord-008530-yni0poh9	622	5	regulation	regulation	NN
cord-008530-yni0poh9	622	6	of	of	IN
cord-008530-yni0poh9	622	7	myeloid	myeloid	JJ
cord-008530-yni0poh9	622	8	progenitor	progenitor	NN
cord-008530-yni0poh9	622	9	cells	cell	NNS
cord-008530-yni0poh9	622	10	in	in	IN
cord-008530-yni0poh9	622	11	vivo	vivo	NN
cord-008530-yni0poh9	622	12	:	:	:
cord-008530-yni0poh9	622	13	evidence	evidence	NN
cord-008530-yni0poh9	622	14	from	from	IN
cord-008530-yni0poh9	622	15	mice	mouse	NNS
cord-008530-yni0poh9	622	16	lacking	lack	VBG
cord-008530-yni0poh9	622	17	the	the	DT
cord-008530-yni0poh9	622	18	murine	murine	JJ
cord-008530-yni0poh9	622	19	IL-8	IL-8	NNP
cord-008530-yni0poh9	622	20	receptor	receptor	NN
cord-008530-yni0poh9	622	21	homologue	homologue	NN
cord-008530-yni0poh9	622	22	Viral	Viral	NNP
cord-008530-yni0poh9	622	23	-	-	HYPH
cord-008530-yni0poh9	622	24	induced	induce	VBN
cord-008530-yni0poh9	622	25	neurodegenerative	neurodegenerative	JJ
cord-008530-yni0poh9	622	26	disease	disease	NN
cord-008530-yni0poh9	623	1	The	the	DT
cord-008530-yni0poh9	623	2	virology	virology	NN
cord-008530-yni0poh9	623	3	and	and	CC
cord-008530-yni0poh9	623	4	immunobiology	immunobiology	NN
cord-008530-yni0poh9	623	5	of	of	IN
cord-008530-yni0poh9	623	6	lymphocytic	lymphocytic	NNP
cord-008530-yni0poh9	623	7	choriomeningitis	choriomeningitis	NNP
cord-008530-yni0poh9	623	8	virus	virus	NN
cord-008530-yni0poh9	623	9	infection	infection	NN
cord-008530-yni0poh9	623	10	Novel	Novel	NNP
cord-008530-yni0poh9	623	11	role	role	NN
cord-008530-yni0poh9	623	12	of	of	IN
cord-008530-yni0poh9	623	13	human	human	JJ
cord-008530-yni0poh9	623	14	CD4	CD4	NNP
cord-008530-yni0poh9	623	15	molecule	molecule	NN
cord-008530-yni0poh9	623	16	identified	identify	VBN
cord-008530-yni0poh9	623	17	in	in	IN
cord-008530-yni0poh9	623	18	neurodegeneration	neurodegeneration	NN
cord-008530-yni0poh9	623	19	Neutrophil	Neutrophil	NNP
cord-008530-yni0poh9	623	20	and	and	CC
cord-008530-yni0poh9	623	21	B	b	NN
cord-008530-yni0poh9	623	22	cell	cell	NN
cord-008530-yni0poh9	623	23	expansion	expansion	NN
cord-008530-yni0poh9	623	24	in	in	IN
cord-008530-yni0poh9	623	25	mice	mouse	NNS
cord-008530-yni0poh9	623	26	that	that	WDT
cord-008530-yni0poh9	623	27	lack	lack	VBP
cord-008530-yni0poh9	623	28	the	the	DT
cord-008530-yni0poh9	623	29	murine	murine	JJ
cord-008530-yni0poh9	623	30	IL-8	IL-8	NNP
cord-008530-yni0poh9	623	31	receptor	receptor	NN
cord-008530-yni0poh9	623	32	homolog	homolog	NN
cord-008530-yni0poh9	623	33	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	623	34	in	in	IN
cord-008530-yni0poh9	623	35	chronic	chronic	JJ
cord-008530-yni0poh9	623	36	progressive	progressive	JJ
cord-008530-yni0poh9	623	37	neurological	neurological	JJ
cord-008530-yni0poh9	623	38	diseases	disease	NNS
cord-008530-yni0poh9	623	39	:	:	:
cord-008530-yni0poh9	624	1	HTLV-1	HTLV-1	NNP
cord-008530-yni0poh9	624	2	associated	associate	VBD
cord-008530-yni0poh9	624	3	myelopathy	myelopathy	NN
cord-008530-yni0poh9	624	4	and	and	CC
cord-008530-yni0poh9	624	5	multiple	multiple	JJ
cord-008530-yni0poh9	624	6	sclerosis	sclerosis	NN
cord-008530-yni0poh9	624	7	Cytokine	cytokine	NN
cord-008530-yni0poh9	624	8	and	and	CC
cord-008530-yni0poh9	624	9	chemokine	chemokine	NN
cord-008530-yni0poh9	624	10	production	production	NN
cord-008530-yni0poh9	624	11	in	in	IN
cord-008530-yni0poh9	624	12	HSV-1	hsv-1	NN
cord-008530-yni0poh9	624	13	latently	latently	RB
cord-008530-yni0poh9	624	14	infected	infect	VBD
cord-008530-yni0poh9	624	15	trigeminal	trigeminal	JJ
cord-008530-yni0poh9	624	16	ganglion	ganglion	NN
cord-008530-yni0poh9	624	17	cell	cell	NN
cord-008530-yni0poh9	624	18	cultures	culture	NNS
cord-008530-yni0poh9	624	19	:	:	:
cord-008530-yni0poh9	625	1	effects	effect	NNS
cord-008530-yni0poh9	625	2	of	of	IN
cord-008530-yni0poh9	625	3	hyperthermic	hyperthermic	JJ
cord-008530-yni0poh9	625	4	stress	stress	NN
cord-008530-yni0poh9	625	5	Monocyte	Monocyte	NNP
cord-008530-yni0poh9	625	6	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	625	7	protein	protein	NN
cord-008530-yni0poh9	625	8	1	1	CD
cord-008530-yni0poh9	625	9	acts	act	NNS
cord-008530-yni0poh9	625	10	as	as	IN
cord-008530-yni0poh9	625	11	a	a	DT
cord-008530-yni0poh9	625	12	T	t	NN
cord-008530-yni0poh9	625	13	-	-	HYPH
cord-008530-yni0poh9	625	14	lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	625	15	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	625	16	Differential	differential	NN
cord-008530-yni0poh9	625	17	chemokine	chemokine	NN
cord-008530-yni0poh9	625	18	induction	induction	NN
cord-008530-yni0poh9	625	19	by	by	IN
cord-008530-yni0poh9	625	20	the	the	DT
cord-008530-yni0poh9	625	21	mouse	mouse	NN
cord-008530-yni0poh9	625	22	adenovirus	adenovirus	NN
cord-008530-yni0poh9	625	23	type-1	type-1	NN
cord-008530-yni0poh9	625	24	in	in	IN
cord-008530-yni0poh9	625	25	the	the	DT
cord-008530-yni0poh9	625	26	central	central	JJ
cord-008530-yni0poh9	625	27	nervous	nervous	JJ
cord-008530-yni0poh9	625	28	system	system	NN
cord-008530-yni0poh9	625	29	susceptible	susceptible	JJ
cord-008530-yni0poh9	625	30	and	and	CC
cord-008530-yni0poh9	625	31	resistant	resistant	JJ
cord-008530-yni0poh9	625	32	strains	strain	NNS
cord-008530-yni0poh9	625	33	of	of	IN
cord-008530-yni0poh9	625	34	mice	mouse	NNS
cord-008530-yni0poh9	625	35	Inactivation	Inactivation	NNP
cord-008530-yni0poh9	625	36	of	of	IN
cord-008530-yni0poh9	625	37	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	625	38	chemokine	chemokine	NN
cord-008530-yni0poh9	625	39	co	co	JJ
cord-008530-yni0poh9	625	40	-	-	NN
cord-008530-yni0poh9	625	41	receptor	receptor	JJ
cord-008530-yni0poh9	625	42	CXCR-4	cxcr-4	NN
cord-008530-yni0poh9	625	43	by	by	IN
cord-008530-yni0poh9	625	44	a	a	DT
cord-008530-yni0poh9	625	45	novel	novel	JJ
cord-008530-yni0poh9	625	46	intrakine	intrakine	NN
cord-008530-yni0poh9	625	47	stategy	stategy	NN
cord-008530-yni0poh9	626	1	In	in	IN
cord-008530-yni0poh9	626	2	vivo	vivo	NN
cord-008530-yni0poh9	626	3	inhibition	inhibition	NN
cord-008530-yni0poh9	626	4	of	of	IN
cord-008530-yni0poh9	626	5	CC	CC	NNP
cord-008530-yni0poh9	626	6	and	and	CC
cord-008530-yni0poh9	626	7	CX3C	CX3C	NNS
cord-008530-yni0poh9	626	8	chemokine	chemokine	NN
cord-008530-yni0poh9	626	9	-	-	HYPH
cord-008530-yni0poh9	626	10	induced	induce	VBN
cord-008530-yni0poh9	626	11	leukocyte	leukocyte	NN
cord-008530-yni0poh9	626	12	infiltration	infiltration	NN
cord-008530-yni0poh9	626	13	and	and	CC
cord-008530-yni0poh9	626	14	attenuation	attenuation	NN
cord-008530-yni0poh9	626	15	of	of	IN
cord-008530-yni0poh9	626	16	glomerulonephritis	glomerulonephritis	NN
cord-008530-yni0poh9	626	17	in	in	IN
cord-008530-yni0poh9	626	18	Wistar	Wistar	NNP
cord-008530-yni0poh9	626	19	-	-	HYPH
cord-008530-yni0poh9	626	20	Kyoto	Kyoto	NNP
cord-008530-yni0poh9	626	21	(	(	-LRB-
cord-008530-yni0poh9	626	22	WKY	wky	NN
cord-008530-yni0poh9	626	23	)	)	-RRB-
cord-008530-yni0poh9	626	24	rats	rat	NNS
cord-008530-yni0poh9	626	25	by	by	IN
cord-008530-yni0poh9	627	1	vMIP	vMIP	NNP
cord-008530-yni0poh9	627	2	-	-	HYPH
cord-008530-yni0poh9	627	3	II	II	NNP
cord-008530-yni0poh9	627	4	The	the	DT
cord-008530-yni0poh9	627	5	beta	beta	JJ
cord-008530-yni0poh9	627	6	-	-	HYPH
cord-008530-yni0poh9	627	7	chemokine	chemokine	NN
cord-008530-yni0poh9	627	8	receptors	receptor	NNS
cord-008530-yni0poh9	627	9	CCR3	CCR3	NNP
cord-008530-yni0poh9	627	10	and	and	CC
cord-008530-yni0poh9	627	11	CCR5	CCR5	NNP
cord-008530-yni0poh9	627	12	facilitate	facilitate	VBP
cord-008530-yni0poh9	627	13	infection	infection	NN
cord-008530-yni0poh9	627	14	by	by	IN
cord-008530-yni0poh9	627	15	primary	primary	JJ
cord-008530-yni0poh9	627	16	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	627	17	isolates	isolate	VBZ
cord-008530-yni0poh9	627	18	Identification	Identification	NNP
cord-008530-yni0poh9	627	19	of	of	IN
cord-008530-yni0poh9	627	20	RANTES	RANTES	NNPS
cord-008530-yni0poh9	627	21	,	,	,
cord-008530-yni0poh9	627	22	MIP-1	MIP-1	NNP
cord-008530-yni0poh9	627	23	alpha	alpha	NN
cord-008530-yni0poh9	627	24	,	,	,
cord-008530-yni0poh9	627	25	and	and	CC
cord-008530-yni0poh9	627	26	MIP-1	MIP-1	NNP
cord-008530-yni0poh9	627	27	beta	beta	NN
cord-008530-yni0poh9	627	28	as	as	IN
cord-008530-yni0poh9	627	29	the	the	DT
cord-008530-yni0poh9	627	30	major	major	JJ
cord-008530-yni0poh9	627	31	HIV	HIV	NNP
cord-008530-yni0poh9	627	32	-	-	HYPH
cord-008530-yni0poh9	627	33	suppressive	suppressive	JJ
cord-008530-yni0poh9	627	34	factors	factor	NNS
cord-008530-yni0poh9	627	35	produced	produce	VBN
cord-008530-yni0poh9	627	36	by	by	IN
cord-008530-yni0poh9	627	37	CD8	CD8	NNP
cord-008530-yni0poh9	627	38	+	+	CC
cord-008530-yni0poh9	627	39	T	T	NNP
cord-008530-yni0poh9	627	40	cells	cell	NNS
cord-008530-yni0poh9	628	1	The	the	DT
cord-008530-yni0poh9	628	2	V3	V3	NNP
cord-008530-yni0poh9	628	3	domain	domain	NN
cord-008530-yni0poh9	628	4	of	of	IN
cord-008530-yni0poh9	628	5	the	the	DT
cord-008530-yni0poh9	628	6	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	628	7	gpl20	gpl20	NNP
cord-008530-yni0poh9	628	8	envelope	envelope	NN
cord-008530-yni0poh9	628	9	glycoprotein	glycoprotein	NN
cord-008530-yni0poh9	628	10	is	be	VBZ
cord-008530-yni0poh9	628	11	critical	critical	JJ
cord-008530-yni0poh9	628	12	for	for	IN
cord-008530-yni0poh9	628	13	chemokinemediated	chemokinemediated	JJ
cord-008530-yni0poh9	628	14	blockade	blockade	NN
cord-008530-yni0poh9	628	15	of	of	IN
cord-008530-yni0poh9	628	16	infection	infection	NN
cord-008530-yni0poh9	628	17	Cloning	cloning	NN
cord-008530-yni0poh9	628	18	,	,	,
cord-008530-yni0poh9	628	19	chromosomal	chromosomal	JJ
cord-008530-yni0poh9	628	20	localization	localization	NN
cord-008530-yni0poh9	628	21	,	,	,
cord-008530-yni0poh9	628	22	and	and	CC
cord-008530-yni0poh9	628	23	RNA	RNA	NNP
cord-008530-yni0poh9	628	24	expression	expression	NN
cord-008530-yni0poh9	628	25	of	of	IN
cord-008530-yni0poh9	628	26	a	a	DT
cord-008530-yni0poh9	628	27	human	human	JJ
cord-008530-yni0poh9	628	28	~	~	CD
cord-008530-yni0poh9	628	29	chemokine	chemokine	NN
cord-008530-yni0poh9	628	30	receptor	receptor	NN
cord-008530-yni0poh9	628	31	-	-	HYPH
cord-008530-yni0poh9	628	32	like	like	JJ
cord-008530-yni0poh9	628	33	gene	gene	NN
cord-008530-yni0poh9	628	34	Gene	gene	NN
cord-008530-yni0poh9	628	35	cloning	cloning	NN
cord-008530-yni0poh9	628	36	,	,	,
cord-008530-yni0poh9	628	37	RNA	RNA	NNP
cord-008530-yni0poh9	628	38	distribution	distribution	NN
cord-008530-yni0poh9	628	39	,	,	,
cord-008530-yni0poh9	628	40	and	and	CC
cord-008530-yni0poh9	628	41	functional	functional	JJ
cord-008530-yni0poh9	628	42	expression	expression	NN
cord-008530-yni0poh9	628	43	of	of	IN
cord-008530-yni0poh9	628	44	mCX3CR1	mcx3cr1	CD
cord-008530-yni0poh9	628	45	,	,	,
cord-008530-yni0poh9	628	46	a	a	DT
cord-008530-yni0poh9	628	47	mouse	mouse	NN
cord-008530-yni0poh9	628	48	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	628	49	receptor	receptor	NN
cord-008530-yni0poh9	628	50	for	for	IN
cord-008530-yni0poh9	628	51	the	the	DT
cord-008530-yni0poh9	628	52	CX3C	CX3C	NNS
cord-008530-yni0poh9	628	53	chemokine	chemokine	NNP
cord-008530-yni0poh9	629	1	fractalldne	fractalldne	NNP
cord-008530-yni0poh9	629	2	Induction	Induction	NNP
cord-008530-yni0poh9	629	3	of	of	IN
cord-008530-yni0poh9	629	4	monocyte	monocyte	NNP
cord-008530-yni0poh9	629	5	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	629	6	protein-1	protein-1	NNP
cord-008530-yni0poh9	629	7	in	in	IN
cord-008530-yni0poh9	629	8	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	629	9	Tat	Tat	NNP
cord-008530-yni0poh9	629	10	-	-	HYPH
cord-008530-yni0poh9	629	11	stimulated	stimulate	VBN
cord-008530-yni0poh9	629	12	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	629	13	and	and	CC
cord-008530-yni0poh9	629	14	elevation	elevation	NN
cord-008530-yni0poh9	629	15	in	in	IN
cord-008530-yni0poh9	629	16	AIDS	AIDS	NNP
cord-008530-yni0poh9	629	17	dementia	dementia	NN
cord-008530-yni0poh9	629	18	Requirement	Requirement	NNP
cord-008530-yni0poh9	629	19	of	of	IN
cord-008530-yni0poh9	629	20	MIP	MIP	NNP
cord-008530-yni0poh9	629	21	-	-	HYPH
cord-008530-yni0poh9	629	22	la	la	NNP
cord-008530-yni0poh9	629	23	for	for	IN
cord-008530-yni0poh9	629	24	an	an	DT
cord-008530-yni0poh9	629	25	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	629	26	response	response	NN
cord-008530-yni0poh9	629	27	to	to	IN
cord-008530-yni0poh9	629	28	viral	viral	JJ
cord-008530-yni0poh9	629	29	infection	infection	NN
cord-008530-yni0poh9	629	30	HHV8-encoded	hhv8-encode	VBN
cord-008530-yni0poh9	630	1	vMIP	vmip	LS
cord-008530-yni0poh9	630	2	-	-	:
cord-008530-yni0poh9	630	3	I	-PRON-	PRP
cord-008530-yni0poh9	630	4	selectively	selectively	RB
cord-008530-yni0poh9	630	5	engages	engage	VBZ
cord-008530-yni0poh9	630	6	chemokine	chemokine	NN
cord-008530-yni0poh9	630	7	receptor	receptor	NN
cord-008530-yni0poh9	630	8	CCR8	CCR8	NNP
cord-008530-yni0poh9	630	9	.	.	.
cord-008530-yni0poh9	631	1	Agonist	agonist	NN
cord-008530-yni0poh9	631	2	and	and	CC
cord-008530-yni0poh9	631	3	antagonist	antagonist	NN
cord-008530-yni0poh9	631	4	profiles	profile	NNS
cord-008530-yni0poh9	631	5	of	of	IN
cord-008530-yni0poh9	631	6	viral	viral	JJ
cord-008530-yni0poh9	631	7	chemokines	chemokine	NNS
cord-008530-yni0poh9	631	8	Abduction	abduction	NN
cord-008530-yni0poh9	631	9	of	of	IN
cord-008530-yni0poh9	631	10	chemokine	chemokine	NN
cord-008530-yni0poh9	631	11	elements	element	NNS
cord-008530-yni0poh9	631	12	by	by	IN
cord-008530-yni0poh9	631	13	Herpesviruses	Herpesviruses	NNP
cord-008530-yni0poh9	631	14	Broad	Broad	NNP
cord-008530-yni0poh9	631	15	spectrum	spectrum	NN
cord-008530-yni0poh9	631	16	chemokine	chemokine	NN
cord-008530-yni0poh9	631	17	antagonistic	antagonistic	JJ
cord-008530-yni0poh9	631	18	activity	activity	NN
cord-008530-yni0poh9	631	19	of	of	IN
cord-008530-yni0poh9	631	20	a	a	DT
cord-008530-yni0poh9	631	21	human	human	JJ
cord-008530-yni0poh9	631	22	poxvirus	poxvirus	NNP
cord-008530-yni0poh9	631	23	chemokine	chemokine	NN
cord-008530-yni0poh9	631	24	homolog	homolog	NN
cord-008530-yni0poh9	631	25	Identification	identification	NN
cord-008530-yni0poh9	631	26	of	of	IN
cord-008530-yni0poh9	631	27	a	a	DT
cord-008530-yni0poh9	631	28	major	major	JJ
cord-008530-yni0poh9	631	29	co	co	NN
cord-008530-yni0poh9	631	30	-	-	NN
cord-008530-yni0poh9	631	31	receptor	receptor	NN
cord-008530-yni0poh9	631	32	for	for	IN
cord-008530-yni0poh9	631	33	primary	primary	JJ
cord-008530-yni0poh9	631	34	isolates	isolate	NNS
cord-008530-yni0poh9	631	35	of	of	IN
cord-008530-yni0poh9	631	36	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	631	37	Expression	expression	NN
cord-008530-yni0poh9	631	38	cloning	cloning	NN
cord-008530-yni0poh9	631	39	of	of	IN
cord-008530-yni0poh9	631	40	new	new	JJ
cord-008530-yni0poh9	631	41	receptors	receptor	NNS
cord-008530-yni0poh9	631	42	used	use	VBN
cord-008530-yni0poh9	631	43	by	by	IN
cord-008530-yni0poh9	631	44	simian	simian	JJ
cord-008530-yni0poh9	631	45	and	and	CC
cord-008530-yni0poh9	631	46	human	human	JJ
cord-008530-yni0poh9	631	47	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	631	48	viruses	viruse	VBZ
cord-008530-yni0poh9	631	49	Differentiation	differentiation	NN
cord-008530-yni0poh9	631	50	-	-	HYPH
cord-008530-yni0poh9	631	51	specific	specific	JJ
cord-008530-yni0poh9	631	52	expression	expression	NN
cord-008530-yni0poh9	631	53	of	of	IN
cord-008530-yni0poh9	631	54	a	a	DT
cord-008530-yni0poh9	631	55	novel	novel	JJ
cord-008530-yni0poh9	631	56	G	g	NN
cord-008530-yni0poh9	631	57	protein	protein	NN
cord-008530-yni0poh9	631	58	-	-	HYPH
cord-008530-yni0poh9	631	59	coupled	couple	VBN
cord-008530-yni0poh9	631	60	receptor	receptor	NN
cord-008530-yni0poh9	631	61	from	from	IN
cord-008530-yni0poh9	631	62	Burkitt	Burkitt	NNP
cord-008530-yni0poh9	631	63	's	's	POS
cord-008530-yni0poh9	631	64	lymphoma	lymphoma	NN
cord-008530-yni0poh9	631	65	Dissection	dissection	NN
cord-008530-yni0poh9	631	66	of	of	IN
cord-008530-yni0poh9	631	67	an	an	DT
cord-008530-yni0poh9	631	68	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	631	69	process	process	NN
cord-008530-yni0poh9	631	70	induced	induce	VBN
cord-008530-yni0poh9	631	71	by	by	IN
cord-008530-yni0poh9	631	72	CD8	CD8	NNP
cord-008530-yni0poh9	631	73	+	+	CC
cord-008530-yni0poh9	631	74	T	T	NNP
cord-008530-yni0poh9	631	75	-	-	HYPH
cord-008530-yni0poh9	631	76	cells	cell	NNS
cord-008530-yni0poh9	632	1	A	a	DT
cord-008530-yni0poh9	632	2	dual	dual	JJ
cord-008530-yni0poh9	632	3	-	-	HYPH
cord-008530-yni0poh9	632	4	tropic	tropic	NN
cord-008530-yni0poh9	632	5	primary	primary	JJ
cord-008530-yni0poh9	632	6	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	632	7	isolate	isolate	VBP
cord-008530-yni0poh9	632	8	that	that	WDT
cord-008530-yni0poh9	632	9	uses	use	VBZ
cord-008530-yni0poh9	632	10	fusin	fusin	NNS
cord-008530-yni0poh9	632	11	and	and	CC
cord-008530-yni0poh9	632	12	the	the	DT
cord-008530-yni0poh9	632	13	beta	beta	NN
cord-008530-yni0poh9	632	14	-	-	HYPH
cord-008530-yni0poh9	632	15	chemokine	chemokine	NN
cord-008530-yni0poh9	632	16	receptors	receptor	NNS
cord-008530-yni0poh9	632	17	CKR-5	CKR-5	NNP
cord-008530-yni0poh9	632	18	,	,	,
cord-008530-yni0poh9	632	19	CKR-3	CKR-3	NNP
cord-008530-yni0poh9	632	20	,	,	,
cord-008530-yni0poh9	633	1	and	and	CC
cord-008530-yni0poh9	633	2	CKR-2b	CKR-2b	NNP
cord-008530-yni0poh9	633	3	as	as	IN
cord-008530-yni0poh9	633	4	fusion	fusion	NN
cord-008530-yni0poh9	633	5	cofactors	cofactor	NNS
cord-008530-yni0poh9	633	6	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	633	7	entry	entry	NN
cord-008530-yni0poh9	633	8	into	into	IN
cord-008530-yni0poh9	633	9	CD4	CD4	NNP
cord-008530-yni0poh9	633	10	+	+	CC
cord-008530-yni0poh9	633	11	cells	cell	NNS
cord-008530-yni0poh9	633	12	is	be	VBZ
cord-008530-yni0poh9	633	13	mediated	mediate	VBN
cord-008530-yni0poh9	633	14	by	by	IN
cord-008530-yni0poh9	633	15	the	the	DT
cord-008530-yni0poh9	633	16	chemokine	chemokine	NN
cord-008530-yni0poh9	633	17	receptor	receptor	NN
cord-008530-yni0poh9	633	18	CC	CC	NNP
cord-008530-yni0poh9	633	19	-	-	HYPH
cord-008530-yni0poh9	633	20	CKR-5	CKR-5	NNP
cord-008530-yni0poh9	634	1	A	a	DT
cord-008530-yni0poh9	634	2	review	review	NN
cord-008530-yni0poh9	634	3	of	of	IN
cord-008530-yni0poh9	634	4	neuronal	neuronal	JJ
cord-008530-yni0poh9	634	5	damage	damage	NN
cord-008530-yni0poh9	634	6	in	in	IN
cord-008530-yni0poh9	634	7	human	human	JJ
cord-008530-yni0poh9	634	8	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	634	9	virus	virus	NN
cord-008530-yni0poh9	634	10	infection	infection	NN
cord-008530-yni0poh9	634	11	:	:	:
cord-008530-yni0poh9	634	12	its	-PRON-	PRP$
cord-008530-yni0poh9	634	13	assessment	assessment	NN
cord-008530-yni0poh9	634	14	,	,	,
cord-008530-yni0poh9	634	15	possible	possible	JJ
cord-008530-yni0poh9	634	16	mechanism	mechanism	NN
cord-008530-yni0poh9	634	17	and	and	CC
cord-008530-yni0poh9	634	18	relationship	relationship	NN
cord-008530-yni0poh9	634	19	to	to	IN
cord-008530-yni0poh9	634	20	dementia	dementia	NN
cord-008530-yni0poh9	634	21	Two	two	CD
cord-008530-yni0poh9	634	22	orphan	orphan	NN
cord-008530-yni0poh9	634	23	seven	seven	CD
cord-008530-yni0poh9	634	24	-	-	HYPH
cord-008530-yni0poh9	634	25	transmembrane	transmembrane	NN
cord-008530-yni0poh9	634	26	segment	segment	NN
cord-008530-yni0poh9	634	27	receptors	receptor	NNS
cord-008530-yni0poh9	634	28	which	which	WDT
cord-008530-yni0poh9	634	29	are	be	VBP
cord-008530-yni0poh9	634	30	expressed	express	VBN
cord-008530-yni0poh9	634	31	in	in	IN
cord-008530-yni0poh9	634	32	CD4-positive	cd4-positive	JJ
cord-008530-yni0poh9	634	33	cells	cell	NNS
cord-008530-yni0poh9	634	34	support	support	VBP
cord-008530-yni0poh9	634	35	simian	simian	JJ
cord-008530-yni0poh9	634	36	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	634	37	virus	virus	NN
cord-008530-yni0poh9	634	38	infection	infection	NN
cord-008530-yni0poh9	634	39	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	634	40	entry	entry	NN
cord-008530-yni0poh9	634	41	cofactor	cofactor	NN
cord-008530-yni0poh9	634	42	:	:	:
cord-008530-yni0poh9	634	43	functional	functional	JJ
cord-008530-yni0poh9	634	44	cDNA	cdna	NN
cord-008530-yni0poh9	634	45	cloning	cloning	NN
cord-008530-yni0poh9	634	46	of	of	IN
cord-008530-yni0poh9	634	47	a	a	DT
cord-008530-yni0poh9	634	48	seven	seven	CD
cord-008530-yni0poh9	634	49	-	-	HYPH
cord-008530-yni0poh9	634	50	transmembrane	transmembrane	NN
cord-008530-yni0poh9	634	51	,	,	,
cord-008530-yni0poh9	634	52	G	g	NN
cord-008530-yni0poh9	634	53	protein	protein	NN
cord-008530-yni0poh9	634	54	-	-	HYPH
cord-008530-yni0poh9	634	55	coupled	couple	VBN
cord-008530-yni0poh9	634	56	receptor	receptor	NN
cord-008530-yni0poh9	634	57	Regulatory	regulatory	JJ
cord-008530-yni0poh9	634	58	mechanisms	mechanism	NNS
cord-008530-yni0poh9	634	59	of	of	IN
cord-008530-yni0poh9	634	60	MuRantes	murante	NNS
cord-008530-yni0poh9	634	61	and	and	CC
cord-008530-yni0poh9	634	62	CRG-2	CRG-2	NNP
cord-008530-yni0poh9	634	63	chemokine	chemokine	NN
cord-008530-yni0poh9	634	64	gene	gene	NN
cord-008530-yni0poh9	634	65	induction	induction	NN
cord-008530-yni0poh9	634	66	in	in	IN
cord-008530-yni0poh9	634	67	central	central	JJ
cord-008530-yni0poh9	634	68	nervous	nervous	JJ
cord-008530-yni0poh9	634	69	system	system	NN
cord-008530-yni0poh9	634	70	glial	glial	NN
cord-008530-yni0poh9	634	71	cells	cell	NNS
cord-008530-yni0poh9	634	72	by	by	IN
cord-008530-yni0poh9	634	73	virus	virus	NN
cord-008530-yni0poh9	634	74	Fractalkine	Fractalkine	NNP
cord-008530-yni0poh9	634	75	and	and	CC
cord-008530-yni0poh9	634	76	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	634	77	mediate	mediate	VB
cord-008530-yni0poh9	634	78	a	a	DT
cord-008530-yni0poh9	634	79	novel	novel	JJ
cord-008530-yni0poh9	634	80	mechanism	mechanism	NN
cord-008530-yni0poh9	634	81	of	of	IN
cord-008530-yni0poh9	634	82	leukocyte	leukocyte	NN
cord-008530-yni0poh9	634	83	capture	capture	NN
cord-008530-yni0poh9	634	84	,	,	,
cord-008530-yni0poh9	634	85	firm	firm	JJ
cord-008530-yni0poh9	634	86	adhesion	adhesion	NN
cord-008530-yni0poh9	634	87	,	,	,
cord-008530-yni0poh9	634	88	and	and	CC
cord-008530-yni0poh9	634	89	activation	activation	NN
cord-008530-yni0poh9	634	90	under	under	IN
cord-008530-yni0poh9	634	91	physiologic	physiologic	JJ
cord-008530-yni0poh9	634	92	flow	flow	NN
cord-008530-yni0poh9	634	93	A	a	DT
cord-008530-yni0poh9	634	94	putative	putative	JJ
cord-008530-yni0poh9	634	95	chemokine	chemokine	NN
cord-008530-yni0poh9	634	96	receptor	receptor	NN
cord-008530-yni0poh9	634	97	,	,	,
cord-008530-yni0poh9	634	98	BLR1	BLR1	NNP
cord-008530-yni0poh9	634	99	,	,	,
cord-008530-yni0poh9	634	100	directs	direct	VBZ
cord-008530-yni0poh9	634	101	B	b	NN
cord-008530-yni0poh9	634	102	cell	cell	NN
cord-008530-yni0poh9	634	103	migration	migration	NN
cord-008530-yni0poh9	634	104	to	to	IN
cord-008530-yni0poh9	634	105	defined	define	VBN
cord-008530-yni0poh9	634	106	lymphoid	lymphoid	JJ
cord-008530-yni0poh9	634	107	organs	organ	NNS
cord-008530-yni0poh9	634	108	and	and	CC
cord-008530-yni0poh9	634	109	specific	specific	JJ
cord-008530-yni0poh9	634	110	anatomic	anatomic	JJ
cord-008530-yni0poh9	634	111	compartments	compartment	NNS
cord-008530-yni0poh9	634	112	of	of	IN
cord-008530-yni0poh9	634	113	the	the	DT
cord-008530-yni0poh9	634	114	spleen	spleen	NN
cord-008530-yni0poh9	634	115	Selective	selective	JJ
cord-008530-yni0poh9	634	116	expression	expression	NN
cord-008530-yni0poh9	634	117	of	of	IN
cord-008530-yni0poh9	634	118	the	the	DT
cord-008530-yni0poh9	634	119	murine	murine	JJ
cord-008530-yni0poh9	634	120	homologue	homologue	NN
cord-008530-yni0poh9	634	121	of	of	IN
cord-008530-yni0poh9	634	122	the	the	DT
cord-008530-yni0poh9	634	123	G	g	NN
cord-008530-yni0poh9	634	124	-	-	HYPH
cord-008530-yni0poh9	634	125	protein	protein	NN
cord-008530-yni0poh9	634	126	-	-	HYPH
cord-008530-yni0poh9	634	127	coupled	couple	VBN
cord-008530-yni0poh9	634	128	receptor	receptor	NN
cord-008530-yni0poh9	634	129	BLR1	BLR1	NNP
cord-008530-yni0poh9	634	130	in	in	IN
cord-008530-yni0poh9	634	131	B	b	NN
cord-008530-yni0poh9	634	132	cell	cell	NN
cord-008530-yni0poh9	634	133	differentiation	differentiation	NN
cord-008530-yni0poh9	634	134	,	,	,
cord-008530-yni0poh9	634	135	B	b	NN
cord-008530-yni0poh9	634	136	cell	cell	NN
cord-008530-yni0poh9	634	137	neoplasia	neoplasia	NN
cord-008530-yni0poh9	634	138	and	and	CC
cord-008530-yni0poh9	634	139	defined	define	VBN
cord-008530-yni0poh9	634	140	areas	area	NNS
cord-008530-yni0poh9	634	141	of	of	IN
cord-008530-yni0poh9	634	142	the	the	DT
cord-008530-yni0poh9	634	143	cerebellum	cerebellum	NN
cord-008530-yni0poh9	634	144	Characterization	characterization	NN
cord-008530-yni0poh9	634	145	of	of	IN
cord-008530-yni0poh9	634	146	the	the	DT
cord-008530-yni0poh9	634	147	CCR2	CCR2	NNP
cord-008530-yni0poh9	634	148	chemokine	chemokine	NN
cord-008530-yni0poh9	634	149	receptor	receptor	NN
cord-008530-yni0poh9	634	150	:	:	:
cord-008530-yni0poh9	634	151	functional	functional	JJ
cord-008530-yni0poh9	634	152	CCR2	CCR2	NNP
cord-008530-yni0poh9	634	153	receptor	receptor	NN
cord-008530-yni0poh9	634	154	expression	expression	NN
cord-008530-yni0poh9	634	155	in	in	IN
cord-008530-yni0poh9	634	156	B	b	NN
cord-008530-yni0poh9	634	157	cells	cell	NNS
cord-008530-yni0poh9	634	158	Controlled	control	VBN
cord-008530-yni0poh9	634	159	recruitment	recruitment	NN
cord-008530-yni0poh9	634	160	of	of	IN
cord-008530-yni0poh9	634	161	monocytes	monocyte	NNS
cord-008530-yni0poh9	634	162	and	and	CC
cord-008530-yni0poh9	634	163	macrophages	macrophage	NNS
cord-008530-yni0poh9	634	164	to	to	IN
cord-008530-yni0poh9	634	165	specific	specific	JJ
cord-008530-yni0poh9	634	166	organs	organ	NNS
cord-008530-yni0poh9	634	167	through	through	IN
cord-008530-yni0poh9	634	168	transgenic	transgenic	JJ
cord-008530-yni0poh9	634	169	expression	expression	NN
cord-008530-yni0poh9	634	170	of	of	IN
cord-008530-yni0poh9	634	171	monocyte	monocyte	NNP
cord-008530-yni0poh9	634	172	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	635	1	protein-1	protein-1	NNP
cord-008530-yni0poh9	635	2	Excitotoxic	Excitotoxic	NNP
cord-008530-yni0poh9	635	3	brain	brain	NN
cord-008530-yni0poh9	635	4	injury	injury	NN
cord-008530-yni0poh9	635	5	stimulates	stimulate	VBZ
cord-008530-yni0poh9	635	6	expression	expression	NN
cord-008530-yni0poh9	635	7	of	of	IN
cord-008530-yni0poh9	635	8	the	the	DT
cord-008530-yni0poh9	635	9	chemokine	chemokine	NN
cord-008530-yni0poh9	635	10	receptor	receptor	NN
cord-008530-yni0poh9	635	11	CCR5	CCR5	NNP
cord-008530-yni0poh9	635	12	in	in	IN
cord-008530-yni0poh9	635	13	neonatal	neonatal	JJ
cord-008530-yni0poh9	635	14	rats	rat	NNS
cord-008530-yni0poh9	636	1	Impaired	impair	VBN
cord-008530-yni0poh9	636	2	host	host	NN
cord-008530-yni0poh9	636	3	defense	defense	NN
cord-008530-yni0poh9	636	4	,	,	,
cord-008530-yni0poh9	636	5	hematopoiesis	hematopoiesis	NNP
cord-008530-yni0poh9	636	6	,	,	,
cord-008530-yni0poh9	636	7	granulomateus	granulomateus	NNP
cord-008530-yni0poh9	636	8	inflammation	inflammation	NN
cord-008530-yni0poh9	636	9	and	and	CC
cord-008530-yni0poh9	636	10	type	type	NN
cord-008530-yni0poh9	636	11	1-type	1-type	CD
cord-008530-yni0poh9	636	12	2	2	CD
cord-008530-yni0poh9	636	13	cytokine	cytokine	NN
cord-008530-yni0poh9	636	14	balance	balance	NN
cord-008530-yni0poh9	636	15	in	in	IN
cord-008530-yni0poh9	636	16	mice	mouse	NNS
cord-008530-yni0poh9	636	17	lacking	lack	VBG
cord-008530-yni0poh9	636	18	CC	cc	NN
cord-008530-yni0poh9	636	19	chemokine	chemokine	NN
cord-008530-yni0poh9	636	20	receptor	receptor	NN
cord-008530-yni0poh9	636	21	1	1	CD
cord-008530-yni0poh9	636	22	Structure	Structure	NNP
cord-008530-yni0poh9	636	23	and	and	CC
cord-008530-yni0poh9	636	24	functional	functional	JJ
cord-008530-yni0poh9	636	25	expression	expression	NN
cord-008530-yni0poh9	636	26	of	of	IN
cord-008530-yni0poh9	636	27	the	the	DT
cord-008530-yni0poh9	636	28	human	human	JJ
cord-008530-yni0poh9	636	29	macrophage	macrophage	NN
cord-008530-yni0poh9	636	30	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	636	31	protein	protein	NN
cord-008530-yni0poh9	636	32	1	1	CD
cord-008530-yni0poh9	636	33	alpha	alpha	NN
cord-008530-yni0poh9	636	34	/	/	SYM
cord-008530-yni0poh9	636	35	RANTES	RANTES	NNP
cord-008530-yni0poh9	636	36	receptor	receptor	NN
cord-008530-yni0poh9	636	37	Human	Human	NNP
cord-008530-yni0poh9	636	38	cytomegalovirus	cytomegalovirus	NN
cord-008530-yni0poh9	636	39	open	open	JJ
cord-008530-yni0poh9	636	40	reading	reading	NN
cord-008530-yni0poh9	636	41	frame	frame	NN
cord-008530-yni0poh9	637	1	US28	US28	NNP
cord-008530-yni0poh9	637	2	encodes	encode	VBZ
cord-008530-yni0poh9	637	3	a	a	DT
cord-008530-yni0poh9	637	4	functional	functional	JJ
cord-008530-yni0poh9	637	5	~	~	CD
cord-008530-yni0poh9	637	6	chemokine	chemokine	NN
cord-008530-yni0poh9	637	7	receptor	receptor	NN
cord-008530-yni0poh9	637	8	Cloning	cloning	NN
cord-008530-yni0poh9	637	9	and	and	CC
cord-008530-yni0poh9	637	10	differential	differential	JJ
cord-008530-yni0poh9	637	11	tissue	tissue	NN
cord-008530-yni0poh9	637	12	-	-	HYPH
cord-008530-yni0poh9	637	13	specific	specific	JJ
cord-008530-yni0poh9	637	14	expression	expression	NN
cord-008530-yni0poh9	637	15	of	of	IN
cord-008530-yni0poh9	637	16	three	three	CD
cord-008530-yni0poh9	637	17	mouse	mouse	NN
cord-008530-yni0poh9	637	18	~	~	CD
cord-008530-yni0poh9	637	19	chemokine	chemokine	NN
cord-008530-yni0poh9	637	20	receptor	receptor	NN
cord-008530-yni0poh9	637	21	-	-	HYPH
cord-008530-yni0poh9	637	22	like	like	JJ
cord-008530-yni0poh9	637	23	genes	gene	NNS
cord-008530-yni0poh9	637	24	,	,	,
cord-008530-yni0poh9	637	25	including	include	VBG
cord-008530-yni0poh9	637	26	the	the	DT
cord-008530-yni0poh9	637	27	gene	gene	NN
cord-008530-yni0poh9	637	28	for	for	IN
cord-008530-yni0poh9	637	29	a	a	DT
cord-008530-yni0poh9	637	30	functional	functional	JJ
cord-008530-yni0poh9	637	31	macrophage	macrophage	NN
cord-008530-yni0poh9	637	32	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	637	33	protein	protein	NN
cord-008530-yni0poh9	637	34	-	-	HYPH
cord-008530-yni0poh9	637	35	la	la	JJ
cord-008530-yni0poh9	637	36	receptor	receptor	NN
cord-008530-yni0poh9	637	37	Apoptotic	Apoptotic	NNP
cord-008530-yni0poh9	637	38	neurons	neuron	NNS
cord-008530-yni0poh9	637	39	in	in	IN
cord-008530-yni0poh9	637	40	brains	brain	NNS
cord-008530-yni0poh9	637	41	from	from	IN
cord-008530-yni0poh9	637	42	paediatric	paediatric	JJ
cord-008530-yni0poh9	637	43	patients	patient	NNS
cord-008530-yni0poh9	637	44	with	with	IN
cord-008530-yni0poh9	637	45	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	637	46	encephalitis	encephalitis	JJ
cord-008530-yni0poh9	637	47	and	and	CC
cord-008530-yni0poh9	637	48	progressive	progressive	JJ
cord-008530-yni0poh9	637	49	encephalopathy	encephalopathy	NN
cord-008530-yni0poh9	638	1	The	the	DT
cord-008530-yni0poh9	638	2	neuropathogenesis	neuropathogenesis	NN
cord-008530-yni0poh9	638	3	of	of	IN
cord-008530-yni0poh9	638	4	the	the	DT
cord-008530-yni0poh9	638	5	AIDS	AIDS	NNP
cord-008530-yni0poh9	638	6	dementia	dementia	NN
cord-008530-yni0poh9	638	7	complex	complex	NNP
cord-008530-yni0poh9	638	8	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	638	9	and	and	CC
cord-008530-yni0poh9	638	10	chemokine	chemokine	NN
cord-008530-yni0poh9	638	11	receptors	receptor	NNS
cord-008530-yni0poh9	638	12	in	in	IN
cord-008530-yni0poh9	638	13	CNS	CNS	NNP
cord-008530-yni0poh9	638	14	pathology	pathology	NN
cord-008530-yni0poh9	638	15	Identification	identification	NN
cord-008530-yni0poh9	638	16	of	of	IN
cord-008530-yni0poh9	638	17	CCR8	CCR8	NNP
cord-008530-yni0poh9	638	18	as	as	IN
cord-008530-yni0poh9	638	19	the	the	DT
cord-008530-yni0poh9	638	20	specific	specific	JJ
cord-008530-yni0poh9	638	21	receptor	receptor	NN
cord-008530-yni0poh9	638	22	for	for	IN
cord-008530-yni0poh9	638	23	the	the	DT
cord-008530-yni0poh9	638	24	human	human	JJ
cord-008530-yni0poh9	638	25	~-chemokine	~-chemokine	NNP
cord-008530-yni0poh9	638	26	1	1	CD
cord-008530-yni0poh9	638	27	-	-	SYM
cord-008530-yni0poh9	638	28	309	309	CD
cord-008530-yni0poh9	638	29	:	:	:
cord-008530-yni0poh9	638	30	cloning	clone	VBG
cord-008530-yni0poh9	638	31	and	and	CC
cord-008530-yni0poh9	638	32	molecular	molecular	JJ
cord-008530-yni0poh9	638	33	characterization	characterization	NN
cord-008530-yni0poh9	638	34	of	of	IN
cord-008530-yni0poh9	638	35	murine	murine	JJ
cord-008530-yni0poh9	638	36	CCR8	CCR8	NNP
cord-008530-yni0poh9	638	37	as	as	IN
cord-008530-yni0poh9	638	38	the	the	DT
cord-008530-yni0poh9	638	39	receptor	receptor	NN
cord-008530-yni0poh9	638	40	for	for	IN
cord-008530-yni0poh9	638	41	TCA-3	TCA-3	NNP
cord-008530-yni0poh9	638	42	Transgeuic	Transgeuic	NNP
cord-008530-yni0poh9	638	43	monocyte	monocyte	JJ
cord-008530-yni0poh9	638	44	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	638	45	protein-1	protein-1	NNP
cord-008530-yni0poh9	638	46	(	(	-LRB-
cord-008530-yni0poh9	638	47	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	638	48	)	)	-RRB-
cord-008530-yni0poh9	639	1	in	in	IN
cord-008530-yni0poh9	639	2	pancreatic	pancreatic	JJ
cord-008530-yni0poh9	639	3	islets	islet	NNS
cord-008530-yni0poh9	639	4	produces	produce	VBZ
cord-008530-yni0poh9	639	5	monocyte	monocyte	NNP
cord-008530-yni0poh9	639	6	-	-	HYPH
cord-008530-yni0poh9	639	7	rich	rich	JJ
cord-008530-yni0poh9	639	8	insulitis	insulitis	NN
cord-008530-yni0poh9	639	9	without	without	IN
cord-008530-yni0poh9	639	10	diabetes	diabetes	NN
cord-008530-yni0poh9	639	11	:	:	:
cord-008530-yni0poh9	640	1	abrogation	abrogation	NN
cord-008530-yni0poh9	640	2	by	by	IN
cord-008530-yni0poh9	640	3	a	a	DT
cord-008530-yni0poh9	640	4	second	second	JJ
cord-008530-yni0poh9	640	5	transgene	transgene	NN
cord-008530-yni0poh9	640	6	expressing	express	VBG
cord-008530-yni0poh9	640	7	systemic	systemic	JJ
cord-008530-yni0poh9	640	8	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	640	9	Mouse	Mouse	NNP
cord-008530-yni0poh9	640	10	adenovirus	adenovirus	NN
cord-008530-yni0poh9	640	11	type	type	NN
cord-008530-yni0poh9	640	12	I	-PRON-	PRP
cord-008530-yni0poh9	640	13	causes	cause	VBZ
cord-008530-yni0poh9	640	14	a	a	DT
cord-008530-yni0poh9	640	15	fatal	fatal	JJ
cord-008530-yni0poh9	640	16	hemorrhagic	hemorrhagic	JJ
cord-008530-yni0poh9	640	17	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	640	18	in	in	IN
cord-008530-yni0poh9	640	19	adult	adult	NN
cord-008530-yni0poh9	640	20	C57BL/6	C57BL/6	NNP
cord-008530-yni0poh9	641	1	but	but	CC
cord-008530-yni0poh9	641	2	not	not	RB
cord-008530-yni0poh9	641	3	BALB	BALB	NNP
cord-008530-yni0poh9	641	4	/	/	SYM
cord-008530-yni0poh9	641	5	c	c	NN
cord-008530-yni0poh9	641	6	mice	mouse	NNS
cord-008530-yni0poh9	642	1	The	the	DT
cord-008530-yni0poh9	642	2	distinction	distinction	NN
cord-008530-yni0poh9	642	3	blurs	blur	VBZ
cord-008530-yni0poh9	642	4	between	between	IN
cord-008530-yni0poh9	642	5	an	an	DT
cord-008530-yni0poh9	642	6	autoimmune	autoimmune	NN
cord-008530-yni0poh9	642	7	versus	versus	IN
cord-008530-yni0poh9	642	8	microbial	microbial	JJ
cord-008530-yni0poh9	642	9	hypothesis	hypothesis	NN
cord-008530-yni0poh9	642	10	in	in	IN
cord-008530-yni0poh9	642	11	multiple	multiple	JJ
cord-008530-yni0poh9	642	12	sclerosis	sclerosis	NN
cord-008530-yni0poh9	642	13	cDNA	cdna	NN
cord-008530-yni0poh9	642	14	cloning	cloning	NN
cord-008530-yni0poh9	642	15	of	of	IN
cord-008530-yni0poh9	642	16	a	a	DT
cord-008530-yni0poh9	642	17	G	g	NN
cord-008530-yni0poh9	642	18	-	-	HYPH
cord-008530-yni0poh9	642	19	protein	protein	NN
cord-008530-yni0poh9	642	20	-	-	HYPH
cord-008530-yni0poh9	642	21	coupled	couple	VBN
cord-008530-yni0poh9	642	22	receptor	receptor	NN
cord-008530-yni0poh9	642	23	expressed	express	VBN
cord-008530-yni0poh9	642	24	in	in	IN
cord-008530-yni0poh9	642	25	rat	rat	NN
cord-008530-yni0poh9	642	26	spinal	spinal	JJ
cord-008530-yni0poh9	642	27	cord	cord	NN
cord-008530-yni0poh9	642	28	and	and	CC
cord-008530-yni0poh9	642	29	brain	brain	NN
cord-008530-yni0poh9	642	30	related	relate	VBN
cord-008530-yni0poh9	642	31	to	to	IN
cord-008530-yni0poh9	642	32	ehemokine	ehemokine	JJ
cord-008530-yni0poh9	642	33	receptors	receptor	NNS
cord-008530-yni0poh9	642	34	Role	role	VBP
cord-008530-yni0poh9	642	35	for	for	IN
cord-008530-yni0poh9	642	36	neuronally	neuronally	RB
cord-008530-yni0poh9	642	37	derived	derive	VBN
cord-008530-yni0poh9	642	38	i	i	PRP
cord-008530-yni0poh9	642	39	~	~	NFP
cord-008530-yni0poh9	642	40	actalkine	actalkine	NN
cord-008530-yni0poh9	642	41	in	in	IN
cord-008530-yni0poh9	642	42	mediating	mediate	VBG
cord-008530-yni0poh9	642	43	interactions	interaction	NNS
cord-008530-yni0poh9	642	44	between	between	IN
cord-008530-yni0poh9	642	45	neurons	neuron	NNS
cord-008530-yni0poh9	642	46	and	and	CC
cord-008530-yni0poh9	642	47	CX3CRl	CX3CRl	NNP
cord-008530-yni0poh9	642	48	-	-	HYPH
cord-008530-yni0poh9	642	49	expressing	express	VBG
cord-008530-yni0poh9	642	50	microglia	microglia	JJ
cord-008530-yni0poh9	642	51	Production	production	NN
cord-008530-yni0poh9	642	52	and	and	CC
cord-008530-yni0poh9	642	53	function	function	NN
cord-008530-yni0poh9	642	54	of	of	IN
cord-008530-yni0poh9	642	55	monocyte	monocyte	NNP
cord-008530-yni0poh9	642	56	chemoattraetant	chemoattraetant	NNP
cord-008530-yni0poh9	642	57	protein-1	protein-1	NNP
cord-008530-yni0poh9	642	58	and	and	CC
cord-008530-yni0poh9	642	59	other	other	JJ
cord-008530-yni0poh9	642	60	~-chemokines	~-chemokine	NNS
cord-008530-yni0poh9	642	61	in	in	IN
cord-008530-yni0poh9	642	62	murine	murine	JJ
cord-008530-yni0poh9	642	63	glial	glial	JJ
cord-008530-yni0poh9	642	64	cells	cell	NNS
cord-008530-yni0poh9	642	65	CCR3	CCR3	NNP
cord-008530-yni0poh9	642	66	and	and	CC
cord-008530-yni0poh9	642	67	CCR5	CCR5	NNP
cord-008530-yni0poh9	642	68	are	be	VBP
cord-008530-yni0poh9	642	69	co	co	NNS
cord-008530-yni0poh9	642	70	-	-	NNS
cord-008530-yni0poh9	642	71	receptors	receptor	NNS
cord-008530-yni0poh9	642	72	for	for	IN
cord-008530-yni0poh9	642	73	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	642	74	infection	infection	NN
cord-008530-yni0poh9	642	75	of	of	IN
cord-008530-yni0poh9	642	76	microglia	microglia	JJ
cord-008530-yni0poh9	642	77	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	642	78	is	be	VBZ
cord-008530-yni0poh9	642	79	produced	produce	VBN
cord-008530-yni0poh9	642	80	by	by	IN
cord-008530-yni0poh9	642	81	NK	NK	NNP
cord-008530-yni0poh9	642	82	cells	cell	NNS
cord-008530-yni0poh9	642	83	and	and	CC
cord-008530-yni0poh9	642	84	attracts	attract	VBZ
cord-008530-yni0poh9	642	85	both	both	DT
cord-008530-yni0poh9	642	86	NK	NK	NNP
cord-008530-yni0poh9	642	87	cells	cell	NNS
cord-008530-yni0poh9	642	88	and	and	CC
cord-008530-yni0poh9	642	89	T	t	NN
cord-008530-yni0poh9	642	90	cells	cell	NNS
cord-008530-yni0poh9	642	91	in	in	IN
cord-008530-yni0poh9	642	92	vivo	vivo	NN
cord-008530-yni0poh9	642	93	Cloning	cloning	NN
cord-008530-yni0poh9	642	94	of	of	IN
cord-008530-yni0poh9	642	95	the	the	DT
cord-008530-yni0poh9	642	96	mouse	mouse	NN
cord-008530-yni0poh9	642	97	fusin	fusin	NNP
cord-008530-yni0poh9	642	98	gene	gene	NNP
cord-008530-yni0poh9	642	99	,	,	,
cord-008530-yni0poh9	642	100	homologue	homologue	NN
cord-008530-yni0poh9	642	101	to	to	IN
cord-008530-yni0poh9	642	102	a	a	DT
cord-008530-yni0poh9	642	103	human	human	JJ
cord-008530-yni0poh9	642	104	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	642	105	co	co	NN
cord-008530-yni0poh9	642	106	-	-	NN
cord-008530-yni0poh9	642	107	factor	factor	NN
cord-008530-yni0poh9	642	108	Isolation	isolation	NN
cord-008530-yni0poh9	642	109	of	of	IN
cord-008530-yni0poh9	642	110	three	three	CD
cord-008530-yni0poh9	642	111	novel	novel	JJ
cord-008530-yni0poh9	642	112	human	human	JJ
cord-008530-yni0poh9	642	113	genes	gene	NNS
cord-008530-yni0poh9	642	114	encoding	encode	VBG
cord-008530-yni0poh9	642	115	G	g	NN
cord-008530-yni0poh9	642	116	protein	protein	NN
cord-008530-yni0poh9	642	117	-	-	HYPH
cord-008530-yni0poh9	642	118	coupled	couple	VBN
cord-008530-yni0poh9	642	119	receptors	receptor	NNS
cord-008530-yni0poh9	643	1	A	a	DT
cord-008530-yni0poh9	643	2	novel	novel	JJ
cord-008530-yni0poh9	643	3	human	human	NN
cord-008530-yni0poh9	643	4	gene	gene	NN
cord-008530-yni0poh9	643	5	encoding	encode	VBG
cord-008530-yni0poh9	643	6	a	a	DT
cord-008530-yni0poh9	643	7	G	g	NN
cord-008530-yni0poh9	643	8	-	-	HYPH
cord-008530-yni0poh9	643	9	protein	protein	NN
cord-008530-yni0poh9	643	10	-	-	HYPH
cord-008530-yni0poh9	643	11	coupled	couple	VBN
cord-008530-yni0poh9	643	12	receptor	receptor	NN
cord-008530-yni0poh9	643	13	(	(	-LRB-
cord-008530-yni0poh9	643	14	GPR15	GPR15	NNP
cord-008530-yni0poh9	643	15	)	)	-RRB-
cord-008530-yni0poh9	643	16	is	be	VBZ
cord-008530-yni0poh9	643	17	located	locate	VBN
cord-008530-yni0poh9	643	18	on	on	IN
cord-008530-yni0poh9	643	19	chromosome	chromosome	NN
cord-008530-yni0poh9	643	20	3	3	CD
cord-008530-yni0poh9	643	21	Neuronal	neuronal	JJ
cord-008530-yni0poh9	643	22	apoptosis	apoptosis	NN
cord-008530-yni0poh9	643	23	induced	induce	VBN
cord-008530-yni0poh9	643	24	by	by	IN
cord-008530-yni0poh9	643	25	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	643	26	gpl20	gpl20	NNP
cord-008530-yni0poh9	643	27	and	and	CC
cord-008530-yni0poh9	643	28	the	the	DT
cord-008530-yni0poh9	643	29	chemokine	chemokine	NN
cord-008530-yni0poh9	643	30	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	643	31	alpha	alpha	NN
cord-008530-yni0poh9	643	32	is	be	VBZ
cord-008530-yni0poh9	643	33	mediated	mediate	VBN
cord-008530-yni0poh9	643	34	by	by	IN
cord-008530-yni0poh9	643	35	the	the	DT
cord-008530-yni0poh9	643	36	chemokine	chemokine	NN
cord-008530-yni0poh9	643	37	receptor	receptor	NN
cord-008530-yni0poh9	643	38	CXCR4	cxcr4	XX
cord-008530-yni0poh9	643	39	Leukocyte	Leukocyte	NNP
cord-008530-yni0poh9	643	40	traffic	traffic	NN
cord-008530-yni0poh9	643	41	in	in	IN
cord-008530-yni0poh9	643	42	the	the	DT
cord-008530-yni0poh9	643	43	central	central	JJ
cord-008530-yni0poh9	643	44	nervous	nervous	JJ
cord-008530-yni0poh9	643	45	system	system	NN
cord-008530-yni0poh9	643	46	:	:	:
cord-008530-yni0poh9	643	47	the	the	DT
cord-008530-yni0poh9	643	48	participants	participant	NNS
cord-008530-yni0poh9	643	49	and	and	CC
cord-008530-yni0poh9	643	50	their	-PRON-	PRP$
cord-008530-yni0poh9	643	51	roles	role	NNS
cord-008530-yni0poh9	643	52	Central	central	JJ
cord-008530-yni0poh9	643	53	nervous	nervous	JJ
cord-008530-yni0poh9	643	54	system	system	NN
cord-008530-yni0poh9	643	55	chemokine	chemokine	NN
cord-008530-yni0poh9	643	56	expression	expression	NN
cord-008530-yni0poh9	643	57	during	during	IN
cord-008530-yni0poh9	643	58	Theiler	Theiler	NNP
cord-008530-yni0poh9	643	59	's	's	POS
cord-008530-yni0poh9	643	60	virus	virus	NN
cord-008530-yni0poh9	643	61	-	-	HYPH
cord-008530-yni0poh9	643	62	induced	induce	VBN
cord-008530-yni0poh9	643	63	demyelinating	demyelinating	NN
cord-008530-yni0poh9	643	64	disease	disease	NN
cord-008530-yni0poh9	643	65	The	the	DT
cord-008530-yni0poh9	643	66	Duffy	Duffy	NNP
cord-008530-yni0poh9	643	67	antigen	antigen	NN
cord-008530-yni0poh9	643	68	receptor	receptor	NN
cord-008530-yni0poh9	643	69	for	for	IN
cord-008530-yni0poh9	643	70	chemokines	chemokine	NNS
cord-008530-yni0poh9	643	71	:	:	:
cord-008530-yni0poh9	643	72	structural	structural	JJ
cord-008530-yni0poh9	643	73	analysis	analysis	NN
cord-008530-yni0poh9	643	74	and	and	CC
cord-008530-yni0poh9	643	75	expression	expression	NN
cord-008530-yni0poh9	643	76	in	in	IN
cord-008530-yni0poh9	643	77	the	the	DT
cord-008530-yni0poh9	643	78	brain	brain	NN
cord-008530-yni0poh9	643	79	Expression	expression	NN
cord-008530-yni0poh9	643	80	of	of	IN
cord-008530-yni0poh9	643	81	chemokine	chemokine	NN
cord-008530-yni0poh9	643	82	receptors	receptor	NNS
cord-008530-yni0poh9	643	83	by	by	IN
cord-008530-yni0poh9	643	84	subsets	subset	NNS
cord-008530-yni0poh9	643	85	of	of	IN
cord-008530-yni0poh9	643	86	neurons	neuron	NNS
cord-008530-yni0poh9	643	87	in	in	IN
cord-008530-yni0poh9	643	88	the	the	DT
cord-008530-yni0poh9	643	89	central	central	JJ
cord-008530-yni0poh9	643	90	nervous	nervous	JJ
cord-008530-yni0poh9	643	91	system	system	NN
cord-008530-yni0poh9	643	92	Inhibition	inhibition	NN
cord-008530-yni0poh9	643	93	of	of	IN
cord-008530-yni0poh9	643	94	microglial	microglial	JJ
cord-008530-yni0poh9	643	95	cell	cell	NN
cord-008530-yni0poh9	643	96	RANTES	rante	NNS
cord-008530-yni0poh9	643	97	production	production	NN
cord-008530-yni0poh9	643	98	by	by	IN
cord-008530-yni0poh9	643	99	IL-10	IL-10	NNP
cord-008530-yni0poh9	643	100	and	and	CC
cord-008530-yni0poh9	643	101	TGF	TGF	NNP
cord-008530-yni0poh9	643	102	-	-	HYPH
cord-008530-yni0poh9	643	103	beta	beta	NN
cord-008530-yni0poh9	643	104	Identification	identification	NN
cord-008530-yni0poh9	643	105	and	and	CC
cord-008530-yni0poh9	643	106	molecular	molecular	JJ
cord-008530-yni0poh9	643	107	characterization	characterization	NN
cord-008530-yni0poh9	643	108	of	of	IN
cord-008530-yni0poh9	643	109	fractalkine	fractalkine	JJ
cord-008530-yni0poh9	643	110	receptor	receptor	NN
cord-008530-yni0poh9	643	111	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	643	112	,	,	,
cord-008530-yni0poh9	643	113	which	which	WDT
cord-008530-yni0poh9	643	114	mediates	mediate	VBZ
cord-008530-yni0poh9	643	115	both	both	DT
cord-008530-yni0poh9	643	116	leukocyte	leukocyte	NN
cord-008530-yni0poh9	643	117	migration	migration	NN
cord-008530-yni0poh9	643	118	and	and	CC
cord-008530-yni0poh9	643	119	adhesion	adhesion	NN
cord-008530-yni0poh9	644	1	The	the	DT
cord-008530-yni0poh9	644	2	G	G	NNP
cord-008530-yni0poh9	644	3	protein	protein	NN
cord-008530-yni0poh9	644	4	-	-	HYPH
cord-008530-yni0poh9	644	5	coupled	couple	VBN
cord-008530-yni0poh9	644	6	receptor	receptor	NN
cord-008530-yni0poh9	644	7	BLR1	BLR1	NNP
cord-008530-yni0poh9	644	8	is	be	VBZ
cord-008530-yni0poh9	644	9	involved	involve	VBN
cord-008530-yni0poh9	644	10	in	in	IN
cord-008530-yni0poh9	644	11	murine	murine	JJ
cord-008530-yni0poh9	644	12	B	b	NN
cord-008530-yni0poh9	644	13	cell	cell	NN
cord-008530-yni0poh9	644	14	differentiation	differentiation	NN
cord-008530-yni0poh9	644	15	and	and	CC
cord-008530-yni0poh9	644	16	is	be	VBZ
cord-008530-yni0poh9	644	17	also	also	RB
cord-008530-yni0poh9	644	18	expressed	express	VBN
cord-008530-yni0poh9	644	19	in	in	IN
cord-008530-yni0poh9	644	20	neuronal	neuronal	JJ
cord-008530-yni0poh9	644	21	tissues	tissue	NNS
cord-008530-yni0poh9	645	1	An	an	DT
cord-008530-yni0poh9	645	2	important	important	JJ
cord-008530-yni0poh9	645	3	role	role	NN
cord-008530-yni0poh9	645	4	for	for	IN
cord-008530-yni0poh9	645	5	the	the	DT
cord-008530-yni0poh9	645	6	chemokine	chemokine	NN
cord-008530-yni0poh9	645	7	macrophage	macrophage	NN
cord-008530-yni0poh9	645	8	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	645	9	protein	protein	NN
cord-008530-yni0poh9	645	10	-	-	HYPH
cord-008530-yni0poh9	645	11	lalpha	lalpha	NNS
cord-008530-yni0poh9	645	12	in	in	IN
cord-008530-yni0poh9	645	13	the	the	DT
cord-008530-yni0poh9	645	14	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	645	15	of	of	IN
cord-008530-yni0poh9	645	16	the	the	DT
cord-008530-yni0poh9	645	17	T	T	NNP
cord-008530-yni0poh9	645	18	cell	cell	NN
cord-008530-yni0poh9	645	19	-	-	HYPH
cord-008530-yni0poh9	645	20	mediated	mediate	VBN
cord-008530-yni0poh9	645	21	autoimmune	autoimmune	JJ
cord-008530-yni0poh9	645	22	disease	disease	NN
cord-008530-yni0poh9	645	23	,	,	,
cord-008530-yni0poh9	645	24	experimental	experimental	JJ
cord-008530-yni0poh9	645	25	autoimmune	autoimmune	JJ
cord-008530-yni0poh9	645	26	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	645	27	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	645	28	regulation	regulation	NN
cord-008530-yni0poh9	645	29	of	of	IN
cord-008530-yni0poh9	645	30	experimental	experimental	JJ
cord-008530-yni0poh9	645	31	autoimmune	autoimmune	JJ
cord-008530-yni0poh9	645	32	encephalomyelitis	encephalomyelitis	NN
cord-008530-yni0poh9	645	33	:	:	:
cord-008530-yni0poh9	646	1	temporal	temporal	JJ
cord-008530-yni0poh9	646	2	and	and	CC
cord-008530-yni0poh9	646	3	spatial	spatial	JJ
cord-008530-yni0poh9	646	4	expression	expression	NN
cord-008530-yni0poh9	646	5	patterns	pattern	NNS
cord-008530-yni0poh9	646	6	govern	govern	VBP
cord-008530-yni0poh9	646	7	disease	disease	NN
cord-008530-yni0poh9	646	8	patbogenesis	patbogenesis	NNP
cord-008530-yni0poh9	646	9	Chemokines	Chemokines	NNP
cord-008530-yni0poh9	646	10	and	and	CC
cord-008530-yni0poh9	646	11	activated	activate	VBD
cord-008530-yni0poh9	646	12	macrophages	macrophage	NNS
cord-008530-yni0poh9	646	13	in	in	IN
cord-008530-yni0poh9	646	14	HIV	HIV	NNP
cord-008530-yni0poh9	646	15	gpl20-induced	gpl20-induced	NNP
cord-008530-yni0poh9	646	16	neuronal	neuronal	JJ
cord-008530-yni0poh9	646	17	apoptosis	apoptosis	NN
cord-008530-yni0poh9	647	1	Beta	beta	NN
cord-008530-yni0poh9	647	2	-	-	HYPH
cord-008530-yni0poh9	647	3	chemokines	chemokine	NNS
cord-008530-yni0poh9	647	4	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	647	5	and	and	CC
cord-008530-yni0poh9	647	6	RANTES	RANTES	NNP
cord-008530-yni0poh9	647	7	are	be	VBP
cord-008530-yni0poh9	647	8	selectively	selectively	RB
cord-008530-yni0poh9	647	9	increased	increase	VBN
cord-008530-yni0poh9	647	10	in	in	IN
cord-008530-yni0poh9	647	11	cerebrospinal	cerebrospinal	JJ
cord-008530-yni0poh9	647	12	fluid	fluid	NN
cord-008530-yni0poh9	647	13	of	of	IN
cord-008530-yni0poh9	647	14	patients	patient	NNS
cord-008530-yni0poh9	647	15	with	with	IN
cord-008530-yni0poh9	647	16	human	human	JJ
cord-008530-yni0poh9	647	17	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	647	18	virus	virus	NN
cord-008530-yni0poh9	647	19	-	-	HYPH
cord-008530-yni0poh9	647	20	associated	associate	VBN
cord-008530-yni0poh9	647	21	dementia	dementia	NN
cord-008530-yni0poh9	647	22	Lymphotactin	Lymphotactin	NNP
cord-008530-yni0poh9	647	23	:	:	:
cord-008530-yni0poh9	647	24	a	a	DT
cord-008530-yni0poh9	647	25	cytokine	cytokine	NN
cord-008530-yni0poh9	647	26	that	that	WDT
cord-008530-yni0poh9	647	27	represents	represent	VBZ
cord-008530-yni0poh9	647	28	a	a	DT
cord-008530-yni0poh9	647	29	new	new	JJ
cord-008530-yni0poh9	647	30	class	class	NN
cord-008530-yni0poh9	647	31	of	of	IN
cord-008530-yni0poh9	647	32	chemokine	chemokine	NN
cord-008530-yni0poh9	648	1	A	a	DT
cord-008530-yni0poh9	648	2	broad	broad	JJ
cord-008530-yni0poh9	648	3	-	-	HYPH
cord-008530-yni0poh9	648	4	spectrum	spectrum	NN
cord-008530-yni0poh9	648	5	chemokine	chemokine	NN
cord-008530-yni0poh9	648	6	antagonist	antagonist	NN
cord-008530-yni0poh9	648	7	encoded	encode	VBN
cord-008530-yni0poh9	648	8	by	by	IN
cord-008530-yni0poh9	648	9	Kaposi	Kaposi	NNP
cord-008530-yni0poh9	648	10	's	's	POS
cord-008530-yni0poh9	648	11	sarcoma	sarcoma	NN
cord-008530-yni0poh9	648	12	-	-	HYPH
cord-008530-yni0poh9	648	13	associated	associate	VBN
cord-008530-yni0poh9	648	14	herpesvirus	herpesvirus	NN
cord-008530-yni0poh9	648	15	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	648	16	receptor	receptor	NN
cord-008530-yni0poh9	648	17	expression	expression	NN
cord-008530-yni0poh9	648	18	and	and	CC
cord-008530-yni0poh9	648	19	signaling	signal	VBG
cord-008530-yni0poh9	648	20	in	in	IN
cord-008530-yni0poh9	648	21	macaque	macaque	NN
cord-008530-yni0poh9	648	22	and	and	CC
cord-008530-yni0poh9	648	23	human	human	JJ
cord-008530-yni0poh9	648	24	fetal	fetal	JJ
cord-008530-yni0poh9	648	25	neurons	neuron	NNS
cord-008530-yni0poh9	648	26	and	and	CC
cord-008530-yni0poh9	648	27	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	648	28	:	:	:
cord-008530-yni0poh9	648	29	implications	implication	NNS
cord-008530-yni0poh9	648	30	for	for	IN
cord-008530-yni0poh9	648	31	the	the	DT
cord-008530-yni0poh9	648	32	neuropathogenesis	neuropathogenesis	NN
cord-008530-yni0poh9	648	33	of	of	IN
cord-008530-yni0poh9	648	34	AIDS	AIDS	NNP
cord-008530-yni0poh9	648	35	Identification	Identification	NNP
cord-008530-yni0poh9	648	36	of	of	IN
cord-008530-yni0poh9	648	37	a	a	DT
cord-008530-yni0poh9	648	38	T	T	NNP
cord-008530-yni0poh9	648	39	cell	cell	NN
cord-008530-yni0poh9	648	40	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	648	41	factor	factor	NN
cord-008530-yni0poh9	648	42	in	in	IN
cord-008530-yni0poh9	648	43	the	the	DT
cord-008530-yni0poh9	648	44	cerebmspinal	cerebmspinal	JJ
cord-008530-yni0poh9	648	45	fluid	fluid	NN
cord-008530-yni0poh9	648	46	of	of	IN
cord-008530-yni0poh9	648	47	HIV	HIV	NNP
cord-008530-yni0poh9	648	48	-	-	HYPH
cord-008530-yni0poh9	648	49	l	l	NNP
cord-008530-yni0poh9	648	50	-	-	HYPH
cord-008530-yni0poh9	648	51	infected	infect	VBN
cord-008530-yni0poh9	648	52	individuals	individual	NNS
cord-008530-yni0poh9	648	53	as	as	IN
cord-008530-yni0poh9	648	54	interferon-7	interferon-7	NNP
cord-008530-yni0poh9	648	55	inducible	inducible	JJ
cord-008530-yni0poh9	648	56	protein	protein	NN
cord-008530-yni0poh9	648	57	10	10	CD
cord-008530-yni0poh9	648	58	Genetic	genetic	JJ
cord-008530-yni0poh9	648	59	differences	difference	NNS
cord-008530-yni0poh9	648	60	between	between	IN
cord-008530-yni0poh9	648	61	blood	blood	NN
cord-008530-yni0poh9	648	62	-	-	HYPH
cord-008530-yni0poh9	648	63	and	and	CC
cord-008530-yni0poh9	648	64	brain	brain	NN
cord-008530-yni0poh9	648	65	-	-	HYPH
cord-008530-yni0poh9	648	66	derived	derive	VBN
cord-008530-yni0poh9	648	67	viral	viral	JJ
cord-008530-yni0poh9	648	68	sequences	sequence	NNS
cord-008530-yni0poh9	648	69	from	from	IN
cord-008530-yni0poh9	648	70	human	human	JJ
cord-008530-yni0poh9	648	71	immnnodeficiency	immnnodeficiency	NNP
cord-008530-yni0poh9	648	72	virus	virus	NN
cord-008530-yni0poh9	648	73	type	type	NN
cord-008530-yni0poh9	648	74	1-infected	1-infected	CD
cord-008530-yni0poh9	648	75	patients	patient	NNS
cord-008530-yni0poh9	648	76	:	:	:
cord-008530-yni0poh9	648	77	evidence	evidence	NN
cord-008530-yni0poh9	648	78	of	of	IN
cord-008530-yni0poh9	648	79	conserved	conserved	JJ
cord-008530-yni0poh9	648	80	elements	element	NNS
cord-008530-yni0poh9	648	81	in	in	IN
cord-008530-yni0poh9	648	82	the	the	DT
cord-008530-yni0poh9	648	83	V3	V3	NNP
cord-008530-yni0poh9	648	84	region	region	NN
cord-008530-yni0poh9	648	85	of	of	IN
cord-008530-yni0poh9	648	86	the	the	DT
cord-008530-yni0poh9	648	87	envelope	envelope	NN
cord-008530-yni0poh9	648	88	protein	protein	NN
cord-008530-yni0poh9	648	89	of	of	IN
cord-008530-yni0poh9	648	90	brain	brain	NN
cord-008530-yni0poh9	648	91	-	-	HYPH
cord-008530-yni0poh9	648	92	derived	derive	VBN
cord-008530-yni0poh9	648	93	sequences	sequence	NNS
cord-008530-yni0poh9	648	94	Functional	functional	JJ
cord-008530-yni0poh9	648	95	characterization	characterization	NN
cord-008530-yni0poh9	648	96	of	of	IN
cord-008530-yni0poh9	648	97	the	the	DT
cord-008530-yni0poh9	648	98	C	C	NNP
cord-008530-yni0poh9	648	99	-	-	HYPH
cord-008530-yni0poh9	648	100	C	C	NNP
cord-008530-yni0poh9	648	101	chemokine	chemokine	NN
cord-008530-yni0poh9	648	102	-	-	HYPH
cord-008530-yni0poh9	648	103	like	like	JJ
cord-008530-yni0poh9	648	104	molecules	molecule	NNS
cord-008530-yni0poh9	648	105	encoded	encode	VBN
cord-008530-yni0poh9	648	106	by	by	IN
cord-008530-yni0poh9	648	107	molluscum	molluscum	NN
cord-008530-yni0poh9	648	108	contagiosum	contagiosum	NN
cord-008530-yni0poh9	648	109	virus	virus	NN
cord-008530-yni0poh9	648	110	types	type	NNS
cord-008530-yni0poh9	648	111	1	1	CD
cord-008530-yni0poh9	648	112	and	and	CC
cord-008530-yni0poh9	648	113	2	2	CD
cord-008530-yni0poh9	648	114	Defects	defect	NNS
cord-008530-yni0poh9	648	115	in	in	IN
cord-008530-yni0poh9	648	116	macrophage	macrophage	NN
cord-008530-yni0poh9	648	117	recruitment	recruitment	NN
cord-008530-yni0poh9	648	118	and	and	CC
cord-008530-yni0poh9	648	119	host	host	NN
cord-008530-yni0poh9	648	120	defense	defense	NN
cord-008530-yni0poh9	648	121	in	in	IN
cord-008530-yni0poh9	648	122	mice	mouse	NNS
cord-008530-yni0poh9	648	123	lacking	lack	VBG
cord-008530-yni0poh9	648	124	the	the	DT
cord-008530-yni0poh9	648	125	CCR2	CCR2	NNP
cord-008530-yni0poh9	648	126	chemokine	chemokine	NN
cord-008530-yni0poh9	648	127	receptor	receptor	NN
cord-008530-yni0poh9	648	128	Severe	severe	JJ
cord-008530-yni0poh9	648	129	reduction	reduction	NN
cord-008530-yni0poh9	648	130	in	in	IN
cord-008530-yni0poh9	648	131	leukocyte	leukocyte	NN
cord-008530-yni0poh9	648	132	adhesion	adhesion	NN
cord-008530-yni0poh9	648	133	and	and	CC
cord-008530-yni0poh9	648	134	monocyte	monocyte	NNP
cord-008530-yni0poh9	648	135	extravasation	extravasation	NN
cord-008530-yni0poh9	648	136	in	in	IN
cord-008530-yni0poh9	648	137	mice	mouse	NNS
cord-008530-yni0poh9	648	138	deficient	deficient	JJ
cord-008530-yni0poh9	648	139	in	in	IN
cord-008530-yni0poh9	648	140	CC	CC	NNP
cord-008530-yni0poh9	648	141	chemokine	chemokine	NN
cord-008530-yni0poh9	648	142	receptor	receptor	NN
cord-008530-yni0poh9	648	143	2	2	CD
cord-008530-yni0poh9	648	144	Chemotactic	Chemotactic	NNP
cord-008530-yni0poh9	648	145	activity	activity	NN
cord-008530-yni0poh9	648	146	on	on	IN
cord-008530-yni0poh9	648	147	mononuclear	mononuclear	JJ
cord-008530-yni0poh9	648	148	cells	cell	NNS
cord-008530-yni0poh9	648	149	in	in	IN
cord-008530-yni0poh9	648	150	the	the	DT
cord-008530-yni0poh9	648	151	cerebrospinal	cerebrospinal	JJ
cord-008530-yni0poh9	648	152	fluid	fluid	NN
cord-008530-yni0poh9	648	153	of	of	IN
cord-008530-yni0poh9	648	154	patients	patient	NNS
cord-008530-yni0poh9	648	155	with	with	IN
cord-008530-yni0poh9	648	156	viral	viral	JJ
cord-008530-yni0poh9	648	157	meningitis	meningitis	NN
cord-008530-yni0poh9	648	158	is	be	VBZ
cord-008530-yni0poh9	648	159	mediated	mediate	VBN
cord-008530-yni0poh9	648	160	by	by	IN
cord-008530-yni0poh9	648	161	interferon	interferon	NN
cord-008530-yni0poh9	648	162	-	-	HYPH
cord-008530-yni0poh9	648	163	gamma	gamma	NN
cord-008530-yni0poh9	648	164	inducible	inducible	JJ
cord-008530-yni0poh9	648	165	protein-10	protein-10	NNP
cord-008530-yni0poh9	648	166	and	and	CC
cord-008530-yni0poh9	648	167	monocyte	monocyte	NNP
cord-008530-yni0poh9	648	168	chemotactic	chemotactic	VBD
cord-008530-yni0poh9	648	169	protein-1	protein-1	NNP
cord-008530-yni0poh9	648	170	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	648	171	and	and	CC
cord-008530-yni0poh9	648	172	chemotaxis	chemotaxis	NN
cord-008530-yni0poh9	648	173	of	of	IN
cord-008530-yni0poh9	648	174	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	648	175	in	in	IN
cord-008530-yni0poh9	648	176	infectious	infectious	JJ
cord-008530-yni0poh9	648	177	meningitis	meningitis	NN
cord-008530-yni0poh9	649	1	Modulating	modulate	VBG
cord-008530-yni0poh9	649	2	chemokines	chemokine	NNS
cord-008530-yni0poh9	649	3	:	:	:
cord-008530-yni0poh9	649	4	more	more	JJR
cord-008530-yni0poh9	649	5	lessons	lesson	NNS
cord-008530-yni0poh9	649	6	from	from	IN
cord-008530-yni0poh9	649	7	viruses	virus	NNS
cord-008530-yni0poh9	649	8	Neuroinvasion	Neuroinvasion	NNP
cord-008530-yni0poh9	649	9	of	of	IN
cord-008530-yni0poh9	649	10	simian	simian	JJ
cord-008530-yni0poh9	649	11	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	649	12	virus	virus	NN
cord-008530-yni0poh9	649	13	coincides	coincide	VBZ
cord-008530-yni0poh9	649	14	with	with	IN
cord-008530-yni0poh9	649	15	increased	increase	VBN
cord-008530-yni0poh9	649	16	numbers	number	NNS
cord-008530-yni0poh9	649	17	of	of	IN
cord-008530-yni0poh9	649	18	perivascular	perivascular	NNP
cord-008530-yni0poh9	649	19	macrophages	macrophage	NNS
cord-008530-yni0poh9	649	20	/	/	SYM
cord-008530-yni0poh9	649	21	microglia	microglia	NNS
cord-008530-yni0poh9	649	22	and	and	CC
cord-008530-yni0poh9	649	23	intrathecal	intrathecal	JJ
cord-008530-yni0poh9	649	24	immune	immune	JJ
cord-008530-yni0poh9	649	25	activation	activation	NN
cord-008530-yni0poh9	649	26	Dynamic	dynamic	JJ
cord-008530-yni0poh9	649	27	regulation	regulation	NN
cord-008530-yni0poh9	649	28	of	of	IN
cord-008530-yni0poh9	649	29	a	a	DT
cord-008530-yni0poh9	649	30	-	-	HYPH
cord-008530-yni0poh9	649	31	and	and	CC
cord-008530-yni0poh9	649	32	~-chemokine	~-chemokine	JJ
cord-008530-yni0poh9	649	33	expression	expression	NN
cord-008530-yni0poh9	649	34	in	in	IN
cord-008530-yni0poh9	649	35	the	the	DT
cord-008530-yni0poh9	649	36	central	central	JJ
cord-008530-yni0poh9	649	37	nervous	nervous	JJ
cord-008530-yni0poh9	649	38	system	system	NN
cord-008530-yni0poh9	649	39	during	during	IN
cord-008530-yni0poh9	649	40	mouse	mouse	NNP
cord-008530-yni0poh9	649	41	hepatitis	hepatitis	NNP
cord-008530-yni0poh9	649	42	virus	virus	NN
cord-008530-yni0poh9	649	43	-	-	HYPH
cord-008530-yni0poh9	649	44	induced	induce	VBN
cord-008530-yni0poh9	649	45	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	649	46	disease	disease	NN
cord-008530-yni0poh9	649	47	Murine	murine	JJ
cord-008530-yni0poh9	649	48	coronavirus	coronavirus	NN
cord-008530-yni0poh9	649	49	infection	infection	NN
cord-008530-yni0poh9	649	50	:	:	:
cord-008530-yni0poh9	649	51	a	a	DT
cord-008530-yni0poh9	649	52	paradigm	paradigm	NN
cord-008530-yni0poh9	649	53	for	for	IN
cord-008530-yni0poh9	649	54	virus	virus	NN
cord-008530-yni0poh9	649	55	-	-	HYPH
cord-008530-yni0poh9	649	56	induced	induce	VBN
cord-008530-yni0poh9	649	57	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	649	58	disease	disease	NN
cord-008530-yni0poh9	649	59	A	a	DT
cord-008530-yni0poh9	649	60	central	central	JJ
cord-008530-yni0poh9	649	61	role	role	NN
cord-008530-yni0poh9	649	62	for	for	IN
cord-008530-yni0poh9	649	63	CD4	CD4	NNP
cord-008530-yni0poh9	649	64	+	+	CC
cord-008530-yni0poh9	649	65	T	T	NNP
cord-008530-yni0poh9	649	66	-	-	HYPH
cord-008530-yni0poh9	649	67	cells	cell	NNS
cord-008530-yni0poh9	649	68	and	and	CC
cord-008530-yni0poh9	649	69	RANTES	RANTES	NNPS
cord-008530-yni0poh9	649	70	in	in	IN
cord-008530-yni0poh9	649	71	virus	virus	NN
cord-008530-yni0poh9	649	72	-	-	HYPH
cord-008530-yni0poh9	649	73	induced	induce	VBN
cord-008530-yni0poh9	649	74	central	central	JJ
cord-008530-yni0poh9	649	75	nervous	nervous	JJ
cord-008530-yni0poh9	649	76	system	system	NN
cord-008530-yni0poh9	649	77	inflammation	inflammation	NN
cord-008530-yni0poh9	649	78	and	and	CC
cord-008530-yni0poh9	649	79	demyelination	demyelination	NN
cord-008530-yni0poh9	649	80	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	649	81	receptors	receptor	NNS
cord-008530-yni0poh9	649	82	in	in	IN
cord-008530-yni0poh9	649	83	the	the	DT
cord-008530-yni0poh9	649	84	human	human	JJ
cord-008530-yni0poh9	649	85	brain	brain	NN
cord-008530-yni0poh9	649	86	and	and	CC
cord-008530-yni0poh9	649	87	their	-PRON-	PRP$
cord-008530-yni0poh9	649	88	relationship	relationship	NN
cord-008530-yni0poh9	649	89	to	to	IN
cord-008530-yni0poh9	649	90	HIV	HIV	NNP
cord-008530-yni0poh9	649	91	infection	infection	NN
cord-008530-yni0poh9	649	92	CXCR-4	CXCR-4	NNP
cord-008530-yni0poh9	649	93	(	(	-LRB-
cord-008530-yni0poh9	649	94	Fusin	Fusin	NNP
cord-008530-yni0poh9	649	95	)	)	-RRB-
cord-008530-yni0poh9	649	96	,	,	,
cord-008530-yni0poh9	649	97	a	a	DT
cord-008530-yni0poh9	649	98	co	co	NN
cord-008530-yni0poh9	649	99	-	-	NN
cord-008530-yni0poh9	649	100	receptor	receptor	NN
cord-008530-yni0poh9	649	101	for	for	IN
cord-008530-yni0poh9	649	102	the	the	DT
cord-008530-yni0poh9	649	103	type	type	NN
cord-008530-yni0poh9	649	104	1	1	CD
cord-008530-yni0poh9	649	105	human	human	JJ
cord-008530-yni0poh9	649	106	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	649	107	virus	virus	NN
cord-008530-yni0poh9	649	108	(	(	-LRB-
cord-008530-yni0poh9	649	109	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	649	110	)	)	-RRB-
cord-008530-yni0poh9	649	111	,	,	,
cord-008530-yni0poh9	649	112	is	be	VBZ
cord-008530-yni0poh9	649	113	expressed	express	VBN
cord-008530-yni0poh9	649	114	in	in	IN
cord-008530-yni0poh9	649	115	the	the	DT
cord-008530-yni0poh9	649	116	human	human	JJ
cord-008530-yni0poh9	649	117	brain	brain	NN
cord-008530-yni0poh9	649	118	in	in	IN
cord-008530-yni0poh9	649	119	a	a	DT
cord-008530-yni0poh9	649	120	variety	variety	NN
cord-008530-yni0poh9	649	121	of	of	IN
cord-008530-yni0poh9	649	122	cell	cell	NN
cord-008530-yni0poh9	649	123	types	type	NNS
cord-008530-yni0poh9	649	124	,	,	,
cord-008530-yni0poh9	649	125	including	include	VBG
cord-008530-yni0poh9	649	126	microglia	microglia	NNS
cord-008530-yni0poh9	649	127	and	and	CC
cord-008530-yni0poh9	649	128	neurons	neuron	NNS
cord-008530-yni0poh9	649	129	Cerebrospinal	cerebrospinal	NN
cord-008530-yni0poh9	649	130	fluid	fluid	JJ
cord-008530-yni0poh9	649	131	beta	beta	NN
cord-008530-yni0poh9	649	132	chemokine	chemokine	NN
cord-008530-yni0poh9	649	133	concentrations	concentration	NNS
cord-008530-yni0poh9	649	134	in	in	IN
cord-008530-yni0poh9	649	135	neurocognitively	neurocognitively	RB
cord-008530-yni0poh9	649	136	impaired	impair	VBN
cord-008530-yni0poh9	649	137	individuals	individual	NNS
cord-008530-yni0poh9	649	138	infected	infect	VBN
cord-008530-yni0poh9	649	139	with	with	IN
cord-008530-yni0poh9	649	140	human	human	JJ
cord-008530-yni0poh9	649	141	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	649	142	virus	virus	NN
cord-008530-yni0poh9	649	143	type	type	NN
cord-008530-yni0poh9	649	144	1	1	CD
cord-008530-yni0poh9	649	145	A	a	DT
cord-008530-yni0poh9	649	146	novel	novel	JJ
cord-008530-yni0poh9	649	147	chemokine	chemokine	NN
cord-008530-yni0poh9	649	148	receptor	receptor	NN
cord-008530-yni0poh9	649	149	-	-	HYPH
cord-008530-yni0poh9	649	150	like	like	JJ
cord-008530-yni0poh9	649	151	protein	protein	NN
cord-008530-yni0poh9	649	152	,	,	,
cord-008530-yni0poh9	649	153	functions	function	VBZ
cord-008530-yni0poh9	649	154	as	as	IN
cord-008530-yni0poh9	649	155	a	a	DT
cord-008530-yni0poh9	649	156	fusion	fusion	NN
cord-008530-yni0poh9	649	157	cofactor	cofactor	NN
cord-008530-yni0poh9	649	158	for	for	IN
cord-008530-yni0poh9	649	159	both	both	DT
cord-008530-yni0poh9	649	160	macrophage	macrophage	NN
cord-008530-yni0poh9	649	161	-	-	HYPH
cord-008530-yni0poh9	649	162	tropic	tropic	NN
cord-008530-yni0poh9	649	163	and	and	CC
cord-008530-yni0poh9	649	164	T	T	NNP
cord-008530-yni0poh9	649	165	cell	cell	NN
cord-008530-yni0poh9	649	166	line	line	NN
cord-008530-yni0poh9	649	167	-	-	HYPH
cord-008530-yni0poh9	649	168	tropic	tropic	NN
cord-008530-yni0poh9	649	169	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	649	170	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	649	171	receptors	receptor	NNS
cord-008530-yni0poh9	649	172	:	:	:
cord-008530-yni0poh9	649	173	keys	key	NNS
cord-008530-yni0poh9	649	174	to	to	IN
cord-008530-yni0poh9	649	175	AIDS	AIDS	NNP
cord-008530-yni0poh9	649	176	pathogenesis	pathogenesis	NN
cord-008530-yni0poh9	649	177	?	?	.
cord-008530-yni0poh9	650	1	Chemokine	chemokine	JJ
cord-008530-yni0poh9	650	2	receptor	receptor	NN
cord-008530-yni0poh9	650	3	specific	specific	JJ
cord-008530-yni0poh9	650	4	for	for	IN
cord-008530-yni0poh9	650	5	IP10	IP10	NNP
cord-008530-yni0poh9	650	6	and	and	CC
cord-008530-yni0poh9	650	7	Mig	Mig	NNP
cord-008530-yni0poh9	650	8	:	:	:
cord-008530-yni0poh9	650	9	structure	structure	NN
cord-008530-yni0poh9	650	10	,	,	,
cord-008530-yni0poh9	650	11	function	function	NN
cord-008530-yni0poh9	650	12	,	,	,
cord-008530-yni0poh9	650	13	and	and	CC
cord-008530-yni0poh9	650	14	expression	expression	NN
cord-008530-yni0poh9	650	15	in	in	IN
cord-008530-yni0poh9	650	16	activated	activate	VBN
cord-008530-yni0poh9	650	17	T	t	NN
cord-008530-yni0poh9	650	18	-	-	HYPH
cord-008530-yni0poh9	650	19	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	650	20	Abnormalities	abnormality	NNS
cord-008530-yni0poh9	650	21	in	in	IN
cord-008530-yni0poh9	650	22	monocyte	monocyte	NNP
cord-008530-yni0poh9	650	23	recruitment	recruitment	NN
cord-008530-yni0poh9	650	24	and	and	CC
cord-008530-yni0poh9	650	25	cytokine	cytokine	JJ
cord-008530-yni0poh9	650	26	expression	expression	NN
cord-008530-yni0poh9	650	27	in	in	IN
cord-008530-yni0poh9	650	28	monocyte	monocyte	NNP
cord-008530-yni0poh9	650	29	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	650	30	protein	protein	NN
cord-008530-yni0poh9	650	31	1-deficient	1-deficient	CD
cord-008530-yni0poh9	650	32	mice	mouse	NNS
cord-008530-yni0poh9	651	1	The	the	DT
cord-008530-yni0poh9	651	2	CXC	CXC	NNP
cord-008530-yni0poh9	651	3	-	-	HYPH
cord-008530-yni0poh9	651	4	chemokine	chemokine	NN
cord-008530-yni0poh9	651	5	,	,	,
cord-008530-yni0poh9	651	6	H174	h174	CD
cord-008530-yni0poh9	651	7	:	:	:
cord-008530-yni0poh9	651	8	expression	expression	NN
cord-008530-yni0poh9	651	9	in	in	IN
cord-008530-yni0poh9	651	10	the	the	DT
cord-008530-yni0poh9	651	11	central	central	JJ
cord-008530-yni0poh9	651	12	nervous	nervous	JJ
cord-008530-yni0poh9	651	13	system	system	NN
cord-008530-yni0poh9	651	14	Impaired	impair	VBN
cord-008530-yni0poh9	651	15	B	b	NN
cord-008530-yni0poh9	651	16	-	-	HYPH
cord-008530-yni0poh9	651	17	lymphopoiesis	lymphopoiesis	NNP
cord-008530-yni0poh9	651	18	,	,	,
cord-008530-yni0poh9	651	19	myelopoiesis	myelopoiesis	NN
cord-008530-yni0poh9	651	20	,	,	,
cord-008530-yni0poh9	651	21	and	and	CC
cord-008530-yni0poh9	651	22	derailed	derail	VBD
cord-008530-yni0poh9	651	23	cerebellar	cerebellar	JJ
cord-008530-yni0poh9	651	24	neuron	neuron	NN
cord-008530-yni0poh9	651	25	migration	migration	NN
cord-008530-yni0poh9	651	26	in	in	IN
cord-008530-yni0poh9	651	27	CXCR4-and	CXCR4-and	NNP
cord-008530-yni0poh9	651	28	SDF	SDF	NNP
cord-008530-yni0poh9	651	29	-	-	HYPH
cord-008530-yni0poh9	651	30	l	l	NN
cord-008530-yni0poh9	651	31	-	-	HYPH
cord-008530-yni0poh9	651	32	deficient	deficient	JJ
cord-008530-yni0poh9	651	33	mice	mouse	NNS
cord-008530-yni0poh9	652	1	Late	late	JJ
cord-008530-yni0poh9	652	2	expression	expression	NN
cord-008530-yni0poh9	652	3	of	of	IN
cord-008530-yni0poh9	652	4	a	a	DT
cord-008530-yni0poh9	652	5	beta	beta	JJ
cord-008530-yni0poh9	652	6	chemokine	chemokine	NN
cord-008530-yni0poh9	652	7	homolog	homolog	NN
cord-008530-yni0poh9	652	8	by	by	IN
cord-008530-yni0poh9	652	9	murine	murine	JJ
cord-008530-yni0poh9	652	10	cytomegalovirus	cytomegalovirus	NN
cord-008530-yni0poh9	652	11	Characterization	characterization	NN
cord-008530-yni0poh9	652	12	of	of	IN
cord-008530-yni0poh9	652	13	fractalkine	fractalkine	NN
cord-008530-yni0poh9	652	14	in	in	IN
cord-008530-yni0poh9	652	15	rat	rat	NN
cord-008530-yni0poh9	652	16	brain	brain	NN
cord-008530-yni0poh9	652	17	cells	cell	NNS
cord-008530-yni0poh9	652	18	:	:	:
cord-008530-yni0poh9	652	19	migratory	migratory	JJ
cord-008530-yni0poh9	652	20	and	and	CC
cord-008530-yni0poh9	652	21	activation	activation	NN
cord-008530-yni0poh9	652	22	signals	signal	NNS
cord-008530-yni0poh9	652	23	for	for	IN
cord-008530-yni0poh9	652	24	CX3CR	CX3CR	NNP
cord-008530-yni0poh9	652	25	-	-	HYPH
cord-008530-yni0poh9	652	26	l	l	NNP
cord-008530-yni0poh9	652	27	-	-	HYPH
cord-008530-yni0poh9	652	28	expressing	express	VBG
cord-008530-yni0poh9	652	29	microglia	microglia	NNP
cord-008530-yni0poh9	652	30	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	653	1	:	:	:
cord-008530-yni0poh9	653	2	what	what	WDT
cord-008530-yni0poh9	653	3	chemokine	chemokine	NN
cord-008530-yni0poh9	653	4	is	be	VBZ
cord-008530-yni0poh9	653	5	that	that	DT
cord-008530-yni0poh9	653	6	?	?	.
cord-008530-yni0poh9	654	1	The	the	DT
cord-008530-yni0poh9	654	2	interferon	interferon	NN
cord-008530-yni0poh9	654	3	-	-	HYPH
cord-008530-yni0poh9	654	4	inducible	inducible	JJ
cord-008530-yni0poh9	654	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	654	6	MuMig	MuMig	NNP
cord-008530-yni0poh9	654	7	and	and	CC
cord-008530-yni0poh9	654	8	Crg-2	Crg-2	NNP
cord-008530-yni0poh9	654	9	exhibit	exhibit	VBP
cord-008530-yni0poh9	654	10	antiviral	antiviral	JJ
cord-008530-yni0poh9	654	11	activity	activity	NN
cord-008530-yni0poh9	654	12	in	in	IN
cord-008530-yni0poh9	654	13	vivo	vivo	NNP
cord-008530-yni0poh9	654	14	Regulation	Regulation	NNP
cord-008530-yni0poh9	654	15	of	of	IN
cord-008530-yni0poh9	654	16	human	human	JJ
cord-008530-yni0poh9	654	17	IP-10	IP-10	NNP
cord-008530-yni0poh9	654	18	gene	gene	NN
cord-008530-yni0poh9	654	19	expression	expression	NN
cord-008530-yni0poh9	654	20	in	in	IN
cord-008530-yni0poh9	654	21	astrocytoma	astrocytoma	NN
cord-008530-yni0poh9	654	22	cells	cell	NNS
cord-008530-yni0poh9	654	23	by	by	IN
cord-008530-yni0poh9	654	24	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	654	25	cytokines	cytokine	NNS
cord-008530-yni0poh9	655	1	The	the	DT
cord-008530-yni0poh9	655	2	chemokine	chemokine	NN
cord-008530-yni0poh9	655	3	system	system	NN
cord-008530-yni0poh9	655	4	:	:	:
cord-008530-yni0poh9	655	5	redundancy	redundancy	NN
cord-008530-yni0poh9	655	6	for	for	IN
cord-008530-yni0poh9	655	7	robust	robust	JJ
cord-008530-yni0poh9	655	8	outputs	output	NNS
cord-008530-yni0poh9	655	9	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	655	10	.	.	.
cord-008530-yni0poh9	656	1	Introduction	introduction	NN
cord-008530-yni0poh9	656	2	and	and	CC
cord-008530-yni0poh9	656	3	overview	overview	NN
cord-008530-yni0poh9	656	4	Cloning	cloning	NN
cord-008530-yni0poh9	656	5	of	of	IN
cord-008530-yni0poh9	656	6	human	human	JJ
cord-008530-yni0poh9	656	7	genes	gene	NNS
cord-008530-yni0poh9	656	8	encoding	encode	VBG
cord-008530-yni0poh9	656	9	novel	novel	NN
cord-008530-yni0poh9	656	10	G	g	NN
cord-008530-yni0poh9	656	11	protein	protein	NN
cord-008530-yni0poh9	656	12	-	-	HYPH
cord-008530-yni0poh9	656	13	coupled	couple	VBN
cord-008530-yni0poh9	656	14	receptors	receptor	NNS
cord-008530-yni0poh9	656	15	Purification	purification	NN
cord-008530-yni0poh9	656	16	and	and	CC
cord-008530-yni0poh9	656	17	characterization	characterization	NN
cord-008530-yni0poh9	656	18	of	of	IN
cord-008530-yni0poh9	656	19	a	a	DT
cord-008530-yni0poh9	656	20	novel	novel	NN
cord-008530-yni0poh9	656	21	monocyte	monocyte	NNP
cord-008530-yni0poh9	656	22	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	656	23	and	and	CC
cord-008530-yni0poh9	656	24	activating	activate	VBG
cord-008530-yni0poh9	656	25	factor	factor	NN
cord-008530-yni0poh9	656	26	produced	produce	VBN
cord-008530-yni0poh9	656	27	by	by	IN
cord-008530-yni0poh9	656	28	a	a	DT
cord-008530-yni0poh9	656	29	human	human	JJ
cord-008530-yni0poh9	656	30	myelomonocytic	myelomonocytic	JJ
cord-008530-yni0poh9	656	31	cell	cell	NN
cord-008530-yni0poh9	656	32	line	line	NN
cord-008530-yni0poh9	657	1	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	657	2	,	,	,
cord-008530-yni0poh9	657	3	MCP-2	MCP-2	NNP
cord-008530-yni0poh9	657	4	and	and	CC
cord-008530-yni0poh9	657	5	MCP-3	MCP-3	NNP
cord-008530-yni0poh9	657	6	expression	expression	NN
cord-008530-yni0poh9	657	7	in	in	IN
cord-008530-yni0poh9	657	8	multiple	multiple	JJ
cord-008530-yni0poh9	657	9	sclerosis	sclerosis	NN
cord-008530-yni0poh9	657	10	lesions	lesion	NNS
cord-008530-yni0poh9	657	11	:	:	:
cord-008530-yni0poh9	657	12	an	an	DT
cord-008530-yni0poh9	657	13	immunohistochemical	immunohistochemical	JJ
cord-008530-yni0poh9	657	14	and	and	CC
cord-008530-yni0poh9	657	15	in	in	IN
cord-008530-yni0poh9	657	16	situ	situ	JJ
cord-008530-yni0poh9	657	17	hybridization	hybridization	NN
cord-008530-yni0poh9	657	18	study	study	NN
cord-008530-yni0poh9	657	19	Astrocyte	Astrocyte	NNP
cord-008530-yni0poh9	657	20	-	-	HYPH
cord-008530-yni0poh9	657	21	specific	specific	JJ
cord-008530-yni0poh9	657	22	expression	expression	NN
cord-008530-yni0poh9	657	23	of	of	IN
cord-008530-yni0poh9	657	24	human	human	JJ
cord-008530-yni0poh9	657	25	T	T	NNP
cord-008530-yni0poh9	657	26	-	-	HYPH
cord-008530-yni0poh9	657	27	cell	cell	NN
cord-008530-yni0poh9	657	28	lymphotropic	lymphotropic	NNP
cord-008530-yni0poh9	657	29	virus	virus	NN
cord-008530-yni0poh9	657	30	type	type	NN
cord-008530-yni0poh9	657	31	1	1	CD
cord-008530-yni0poh9	657	32	(	(	-LRB-
cord-008530-yni0poh9	657	33	HTLV-1	HTLV-1	NNP
cord-008530-yni0poh9	657	34	)	)	-RRB-
cord-008530-yni0poh9	657	35	Tax	tax	NN
cord-008530-yni0poh9	657	36	:	:	:
cord-008530-yni0poh9	657	37	induction	induction	NN
cord-008530-yni0poh9	657	38	of	of	IN
cord-008530-yni0poh9	657	39	tumor	tumor	NN
cord-008530-yni0poh9	657	40	necrosis	necrosis	NN
cord-008530-yni0poh9	657	41	factor	factor	NN
cord-008530-yni0poh9	657	42	alpha	alpha	NN
cord-008530-yni0poh9	657	43	and	and	CC
cord-008530-yni0poh9	657	44	susceptibility	susceptibility	NN
cord-008530-yni0poh9	657	45	to	to	IN
cord-008530-yni0poh9	657	46	lysis	lysis	NN
cord-008530-yni0poh9	657	47	by	by	IN
cord-008530-yni0poh9	657	48	CD8	CD8	NNP
cord-008530-yni0poh9	657	49	+	+	SYM
cord-008530-yni0poh9	657	50	HTLV	HTLV	NNP
cord-008530-yni0poh9	657	51	-	-	HYPH
cord-008530-yni0poh9	657	52	l	l	NN
cord-008530-yni0poh9	657	53	-	-	HYPH
cord-008530-yni0poh9	657	54	specific	specific	JJ
cord-008530-yni0poh9	657	55	cytotoxic	cytotoxic	JJ
cord-008530-yni0poh9	657	56	T	t	NN
cord-008530-yni0poh9	657	57	cells	cell	NNS
cord-008530-yni0poh9	657	58	Developmental	developmental	JJ
cord-008530-yni0poh9	657	59	expression	expression	NN
cord-008530-yni0poh9	657	60	of	of	IN
cord-008530-yni0poh9	657	61	monocyte	monocyte	NNP
cord-008530-yni0poh9	657	62	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	657	63	protein-1	protein-1	NNP
cord-008530-yni0poh9	657	64	in	in	IN
cord-008530-yni0poh9	657	65	the	the	DT
cord-008530-yni0poh9	657	66	human	human	JJ
cord-008530-yni0poh9	657	67	cerebellum	cerebellum	NN
cord-008530-yni0poh9	657	68	and	and	CC
cord-008530-yni0poh9	657	69	brainstem	brainstem	NNP
cord-008530-yni0poh9	657	70	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	657	71	and	and	CC
cord-008530-yni0poh9	657	72	chemokine	chemokine	NN
cord-008530-yni0poh9	657	73	receptors	receptor	NNS
cord-008530-yni0poh9	657	74	in	in	IN
cord-008530-yni0poh9	657	75	the	the	DT
cord-008530-yni0poh9	657	76	CNS	CNS	NNP
cord-008530-yni0poh9	657	77	:	:	:
cord-008530-yni0poh9	657	78	a	a	DT
cord-008530-yni0poh9	657	79	possible	possible	JJ
cord-008530-yni0poh9	657	80	role	role	NN
cord-008530-yni0poh9	657	81	in	in	IN
cord-008530-yni0poh9	657	82	neuroinflammation	neuroinflammation	NN
cord-008530-yni0poh9	657	83	and	and	CC
cord-008530-yni0poh9	657	84	patterning	pattern	VBG
cord-008530-yni0poh9	657	85	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	657	86	regulate	regulate	VBP
cord-008530-yni0poh9	657	87	hippocampal	hippocampal	JJ
cord-008530-yni0poh9	657	88	neuronal	neuronal	JJ
cord-008530-yni0poh9	657	89	signaling	signaling	NN
cord-008530-yni0poh9	657	90	and	and	CC
cord-008530-yni0poh9	658	1	gp120	gp120	NNP
cord-008530-yni0poh9	658	2	neurotoxicity	neurotoxicity	NN
cord-008530-yni0poh9	659	1	The	the	DT
cord-008530-yni0poh9	659	2	role	role	NN
cord-008530-yni0poh9	659	3	of	of	IN
cord-008530-yni0poh9	659	4	CCR5	CCR5	NNP
cord-008530-yni0poh9	659	5	and	and	CC
cord-008530-yni0poh9	659	6	CCR2	CCR2	NNP
cord-008530-yni0poh9	659	7	polymorphisms	polymorphism	NNS
cord-008530-yni0poh9	659	8	in	in	IN
cord-008530-yni0poh9	659	9	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	659	10	transmission	transmission	NN
cord-008530-yni0poh9	659	11	and	and	CC
cord-008530-yni0poh9	659	12	disease	disease	NN
cord-008530-yni0poh9	659	13	progression	progression	NN
cord-008530-yni0poh9	659	14	Macrophage	Macrophage	NNP
cord-008530-yni0poh9	659	15	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	659	16	protein	protein	NN
cord-008530-yni0poh9	659	17	-	-	HYPH
cord-008530-yni0poh9	659	18	la	la	NN
cord-008530-yni0poh9	659	19	in	in	IN
cord-008530-yni0poh9	659	20	the	the	DT
cord-008530-yni0poh9	659	21	cerebrospinal	cerebrospinal	JJ
cord-008530-yni0poh9	659	22	fluid	fluid	NN
cord-008530-yni0poh9	659	23	of	of	IN
cord-008530-yni0poh9	659	24	patients	patient	NNS
cord-008530-yni0poh9	659	25	with	with	IN
cord-008530-yni0poh9	659	26	multiple	multiple	JJ
cord-008530-yni0poh9	659	27	sclerosis	sclerosis	NN
cord-008530-yni0poh9	659	28	and	and	CC
cord-008530-yni0poh9	659	29	other	other	JJ
cord-008530-yni0poh9	659	30	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	659	31	neurological	neurological	JJ
cord-008530-yni0poh9	659	32	diseases	disease	NNS
cord-008530-yni0poh9	660	1	Tropical	tropical	JJ
cord-008530-yni0poh9	660	2	spastic	spastic	JJ
cord-008530-yni0poh9	660	3	paraparesis	paraparesis	NN
cord-008530-yni0poh9	660	4	:	:	:
cord-008530-yni0poh9	660	5	a	a	DT
cord-008530-yni0poh9	660	6	model	model	NN
cord-008530-yni0poh9	660	7	of	of	IN
cord-008530-yni0poh9	660	8	virus	virus	NN
cord-008530-yni0poh9	660	9	-	-	HYPH
cord-008530-yni0poh9	660	10	induced	induce	VBN
cord-008530-yni0poh9	660	11	,	,	,
cord-008530-yni0poh9	660	12	cytotexic	cytotexic	NNP
cord-008530-yni0poh9	660	13	T	t	NN
cord-008530-yni0poh9	660	14	-	-	HYPH
cord-008530-yni0poh9	660	15	cell	cell	NN
cord-008530-yni0poh9	660	16	-	-	HYPH
cord-008530-yni0poh9	660	17	mediated	mediate	VBN
cord-008530-yni0poh9	660	18	demyelination	demyelination	NN
cord-008530-yni0poh9	660	19	?	?	.
cord-008530-yni0poh9	661	1	Lymphocyte	lymphocyte	NN
cord-008530-yni0poh9	661	2	responses	response	NNS
cord-008530-yni0poh9	661	3	to	to	IN
cord-008530-yni0poh9	661	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	661	5	Cloning	cloning	NN
cord-008530-yni0poh9	661	6	of	of	IN
cord-008530-yni0poh9	661	7	ATAC	ATAC	NNP
cord-008530-yni0poh9	661	8	,	,	,
cord-008530-yni0poh9	661	9	an	an	DT
cord-008530-yni0poh9	661	10	activation	activation	NN
cord-008530-yni0poh9	661	11	-	-	HYPH
cord-008530-yni0poh9	661	12	induced	induce	VBN
cord-008530-yni0poh9	661	13	,	,	,
cord-008530-yni0poh9	661	14	chemokine	chemokine	NN
cord-008530-yni0poh9	661	15	-	-	HYPH
cord-008530-yni0poh9	661	16	related	relate	VBN
cord-008530-yni0poh9	661	17	molecule	molecule	NN
cord-008530-yni0poh9	661	18	exclusively	exclusively	RB
cord-008530-yni0poh9	661	19	expressed	express	VBN
cord-008530-yni0poh9	661	20	in	in	IN
cord-008530-yni0poh9	661	21	CD8	CD8	NNP
cord-008530-yni0poh9	661	22	+	+	CC
cord-008530-yni0poh9	661	23	T	T	NNP
cord-008530-yni0poh9	661	24	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	661	25	Molecular	molecular	JJ
cord-008530-yni0poh9	661	26	piracy	piracy	NN
cord-008530-yni0poh9	661	27	of	of	IN
cord-008530-yni0poh9	661	28	chemokine	chemokine	NN
cord-008530-yni0poh9	661	29	receptors	receptor	NNS
cord-008530-yni0poh9	661	30	by	by	IN
cord-008530-yni0poh9	661	31	herpesviruses	herpesviruses	NNP
cord-008530-yni0poh9	661	32	.	.	.
cord-008530-yni0poh9	662	1	Infectious	infectious	JJ
cord-008530-yni0poh9	662	2	Agents	Agents	NNPS
cord-008530-yni0poh9	662	3	Dis	Dis	NNP
cord-008530-yni0poh9	662	4	Signal	Signal	NNP
cord-008530-yni0poh9	662	5	transduction	transduction	NN
cord-008530-yni0poh9	662	6	and	and	CC
cord-008530-yni0poh9	662	7	ligand	ligand	NN
cord-008530-yni0poh9	662	8	specificity	specificity	NN
cord-008530-yni0poh9	662	9	of	of	IN
cord-008530-yni0poh9	662	10	the	the	DT
cord-008530-yni0poh9	662	11	human	human	JJ
cord-008530-yni0poh9	662	12	monocyte	monocyte	NNP
cord-008530-yni0poh9	662	13	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	662	14	protein-1	protein-1	NNP
cord-008530-yni0poh9	662	15	receptor	receptor	NN
cord-008530-yni0poh9	662	16	in	in	IN
cord-008530-yni0poh9	662	17	transfected	transfecte	VBN
cord-008530-yni0poh9	662	18	embryonic	embryonic	JJ
cord-008530-yni0poh9	662	19	kidney	kidney	NN
cord-008530-yni0poh9	662	20	cells	cell	NNS
cord-008530-yni0poh9	662	21	Defects	defect	NNS
cord-008530-yni0poh9	662	22	of	of	IN
cord-008530-yni0poh9	662	23	B	b	NN
cord-008530-yni0poh9	662	24	-	-	HYPH
cord-008530-yni0poh9	662	25	cell	cell	NN
cord-008530-yni0poh9	662	26	lymphopoiesis	lymphopoiesis	NN
cord-008530-yni0poh9	662	27	and	and	CC
cord-008530-yni0poh9	662	28	bone	bone	NN
cord-008530-yni0poh9	662	29	-	-	HYPH
cord-008530-yni0poh9	662	30	marrow	marrow	NN
cord-008530-yni0poh9	662	31	myelopoiesis	myelopoiesis	NN
cord-008530-yni0poh9	662	32	in	in	IN
cord-008530-yni0poh9	662	33	mice	mouse	NNS
cord-008530-yni0poh9	662	34	lacking	lack	VBG
cord-008530-yni0poh9	662	35	the	the	DT
cord-008530-yni0poh9	662	36	CXC	CXC	NNP
cord-008530-yni0poh9	662	37	chemokine	chemokine	NN
cord-008530-yni0poh9	662	38	PBSF	PBSF	NNP
cord-008530-yni0poh9	662	39	/	/	SYM
cord-008530-yni0poh9	662	40	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	663	1	A	a	DT
cord-008530-yni0poh9	663	2	novel	novel	JJ
cord-008530-yni0poh9	663	3	CXC	CXC	NNP
cord-008530-yni0poh9	663	4	chemokine	chemokine	NN
cord-008530-yni0poh9	663	5	PBSF	PBSF	NNP
cord-008530-yni0poh9	663	6	/	/	SYM
cord-008530-yni0poh9	663	7	SDF-1	SDF-1	NNP
cord-008530-yni0poh9	663	8	and	and	CC
cord-008530-yni0poh9	663	9	its	-PRON-	PRP$
cord-008530-yni0poh9	663	10	receptor	receptor	NN
cord-008530-yni0poh9	663	11	CXCR4	cxcr4	XX
cord-008530-yni0poh9	663	12	:	:	:
cord-008530-yni0poh9	663	13	their	-PRON-	PRP$
cord-008530-yni0poh9	663	14	functions	function	NNS
cord-008530-yni0poh9	663	15	in	in	IN
cord-008530-yni0poh9	663	16	development	development	NN
cord-008530-yni0poh9	663	17	,	,	,
cord-008530-yni0poh9	663	18	hematopoiesis	hematopoiesis	NN
cord-008530-yni0poh9	663	19	and	and	CC
cord-008530-yni0poh9	663	20	HIV	HIV	NNP
cord-008530-yni0poh9	663	21	infection	infection	NN
cord-008530-yni0poh9	663	22	Induction	Induction	NNP
cord-008530-yni0poh9	663	23	of	of	IN
cord-008530-yni0poh9	663	24	IP-10	IP-10	NNP
cord-008530-yni0poh9	663	25	chemokine	chemokine	NN
cord-008530-yni0poh9	663	26	promoter	promoter	NN
cord-008530-yni0poh9	663	27	by	by	IN
cord-008530-yni0poh9	663	28	measles	measles	NNP
cord-008530-yni0poh9	663	29	virus	virus	NN
cord-008530-yni0poh9	663	30	:	:	:
cord-008530-yni0poh9	663	31	comparison	comparison	NN
cord-008530-yni0poh9	663	32	with	with	IN
cord-008530-yni0poh9	663	33	interferon	interferon	NN
cord-008530-yni0poh9	663	34	-	-	HYPH
cord-008530-yni0poh9	663	35	gamma	gamma	NN
cord-008530-yni0poh9	663	36	shows	show	VBZ
cord-008530-yni0poh9	663	37	the	the	DT
cord-008530-yni0poh9	663	38	use	use	NN
cord-008530-yni0poh9	663	39	of	of	IN
cord-008530-yni0poh9	663	40	the	the	DT
cord-008530-yni0poh9	663	41	same	same	JJ
cord-008530-yni0poh9	663	42	response	response	NN
cord-008530-yni0poh9	663	43	element	element	NN
cord-008530-yni0poh9	663	44	but	but	CC
cord-008530-yni0poh9	663	45	with	with	IN
cord-008530-yni0poh9	663	46	differential	differential	JJ
cord-008530-yni0poh9	663	47	DNA	dna	NN
cord-008530-yni0poh9	663	48	-	-	HYPH
cord-008530-yni0poh9	663	49	protein	protein	NN
cord-008530-yni0poh9	663	50	binding	binding	NN
cord-008530-yni0poh9	663	51	profiles	profile	NNS
cord-008530-yni0poh9	663	52	Molecular	molecular	JJ
cord-008530-yni0poh9	663	53	cloning	clone	VBG
cord-008530-yni0poh9	663	54	,	,	,
cord-008530-yni0poh9	663	55	functional	functional	JJ
cord-008530-yni0poh9	663	56	expression	expression	NN
cord-008530-yni0poh9	663	57	,	,	,
cord-008530-yni0poh9	663	58	and	and	CC
cord-008530-yni0poh9	663	59	signaling	signal	VBG
cord-008530-yni0poh9	663	60	characteristics	characteristic	NNS
cord-008530-yni0poh9	663	61	of	of	IN
cord-008530-yni0poh9	663	62	a	a	DT
cord-008530-yni0poh9	663	63	C	C	NNP
cord-008530-yni0poh9	663	64	-	-	HYPH
cord-008530-yni0poh9	663	65	C	c	NN
cord-008530-yni0poh9	663	66	chemokine	chemokine	NN
cord-008530-yni0poh9	663	67	receptor	receptor	NN
cord-008530-yni0poh9	663	68	Localization	Localization	NNP
cord-008530-yni0poh9	663	69	of	of	IN
cord-008530-yni0poh9	663	70	fractalkine	fractalkine	NN
cord-008530-yni0poh9	663	71	and	and	CC
cord-008530-yni0poh9	663	72	CX3CR1	CX3CR1	NNP
cord-008530-yni0poh9	663	73	mRNAs	mRNAs	NNPS
cord-008530-yni0poh9	663	74	in	in	IN
cord-008530-yni0poh9	663	75	rat	rat	NN
cord-008530-yni0poh9	663	76	brain	brain	NN
cord-008530-yni0poh9	663	77	:	:	:
cord-008530-yni0poh9	663	78	does	do	VBZ
cord-008530-yni0poh9	663	79	fractalkine	fractalkine	NNP
cord-008530-yni0poh9	663	80	play	play	VB
cord-008530-yni0poh9	663	81	a	a	DT
cord-008530-yni0poh9	663	82	role	role	NN
cord-008530-yni0poh9	663	83	in	in	IN
cord-008530-yni0poh9	663	84	signaling	signal	VBG
cord-008530-yni0poh9	663	85	from	from	IN
cord-008530-yni0poh9	663	86	neuron	neuron	NN
cord-008530-yni0poh9	663	87	to	to	IN
cord-008530-yni0poh9	663	88	microglia	microglia	NN
cord-008530-yni0poh9	663	89	?	?	.
cord-008530-yni0poh9	664	1	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	664	2	infection	infection	NN
cord-008530-yni0poh9	664	3	in	in	IN
cord-008530-yni0poh9	664	4	a	a	DT
cord-008530-yni0poh9	664	5	man	man	NN
cord-008530-yni0poh9	664	6	homozygous	homozygous	JJ
cord-008530-yni0poh9	664	7	for	for	IN
cord-008530-yni0poh9	664	8	CCR5	CCR5	NNP
cord-008530-yni0poh9	664	9	delta	delta	NN
cord-008530-yni0poh9	664	10	32	32	CD
cord-008530-yni0poh9	665	1	The	the	DT
cord-008530-yni0poh9	665	2	CXC	CXC	NNP
cord-008530-yni0poh9	665	3	chemokine	chemokine	NN
cord-008530-yni0poh9	665	4	SDF-1	sdf-1	NN
cord-008530-yni0poh9	665	5	is	be	VBZ
cord-008530-yni0poh9	665	6	the	the	DT
cord-008530-yni0poh9	665	7	ligand	ligand	NN
cord-008530-yni0poh9	665	8	for	for	IN
cord-008530-yni0poh9	665	9	LESTR	LESTR	NNP
cord-008530-yni0poh9	665	10	/	/	SYM
cord-008530-yni0poh9	665	11	fusin	fusin	NNS
cord-008530-yni0poh9	665	12	and	and	CC
cord-008530-yni0poh9	665	13	prevents	prevent	VBZ
cord-008530-yni0poh9	665	14	infection	infection	NN
cord-008530-yni0poh9	665	15	by	by	IN
cord-008530-yni0poh9	665	16	T	t	NN
cord-008530-yni0poh9	665	17	-	-	HYPH
cord-008530-yni0poh9	665	18	cell	cell	NN
cord-008530-yni0poh9	665	19	-	-	HYPH
cord-008530-yni0poh9	665	20	line	line	NN
cord-008530-yni0poh9	665	21	-	-	HYPH
cord-008530-yni0poh9	665	22	adapted	adapt	VBN
cord-008530-yni0poh9	665	23	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	665	24	Apoptesis	Apoptesis	NNP
cord-008530-yni0poh9	665	25	induced	induce	VBN
cord-008530-yni0poh9	665	26	by	by	IN
cord-008530-yni0poh9	665	27	infection	infection	NN
cord-008530-yni0poh9	665	28	of	of	IN
cord-008530-yni0poh9	665	29	primary	primary	JJ
cord-008530-yni0poh9	665	30	brain	brain	NN
cord-008530-yni0poh9	665	31	cultures	culture	NNS
cord-008530-yni0poh9	665	32	with	with	IN
cord-008530-yni0poh9	665	33	diverse	diverse	JJ
cord-008530-yni0poh9	665	34	human	human	JJ
cord-008530-yni0poh9	665	35	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	665	36	virus	virus	NN
cord-008530-yni0poh9	665	37	type	type	NN
cord-008530-yni0poh9	666	1	I	-PRON-	PRP
cord-008530-yni0poh9	666	2	isolates	isolate	VBZ
cord-008530-yni0poh9	666	3	:	:	:
cord-008530-yni0poh9	667	1	evidence	evidence	NN
cord-008530-yni0poh9	667	2	for	for	IN
cord-008530-yni0poh9	667	3	a	a	DT
cord-008530-yni0poh9	667	4	role	role	NN
cord-008530-yni0poh9	667	5	of	of	IN
cord-008530-yni0poh9	667	6	the	the	DT
cord-008530-yni0poh9	667	7	envelope	envelope	NN
cord-008530-yni0poh9	667	8	Expression	expression	NN
cord-008530-yni0poh9	667	9	of	of	IN
cord-008530-yni0poh9	667	10	stromal	stromal	JJ
cord-008530-yni0poh9	667	11	cell	cell	NN
cord-008530-yni0poh9	667	12	-	-	HYPH
cord-008530-yni0poh9	667	13	derived	derive	VBN
cord-008530-yni0poh9	667	14	factor-1	factor-1	NNP
cord-008530-yni0poh9	667	15	and	and	CC
cord-008530-yni0poh9	667	16	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	667	17	chemokine	chemokine	NN
cord-008530-yni0poh9	667	18	receptor	receptor	NN
cord-008530-yni0poh9	667	19	mRNAs	mrnas	CD
cord-008530-yni0poh9	667	20	in	in	IN
cord-008530-yni0poh9	667	21	cultured	cultured	JJ
cord-008530-yni0poh9	667	22	rat	rat	NN
cord-008530-yni0poh9	667	23	glial	glial	NN
cord-008530-yni0poh9	667	24	and	and	CC
cord-008530-yni0poh9	667	25	neuronal	neuronal	JJ
cord-008530-yni0poh9	667	26	cells	cell	NNS
cord-008530-yni0poh9	668	1	Inflammatory	inflammatory	JJ
cord-008530-yni0poh9	668	2	cytokines	cytokine	NNS
cord-008530-yni0poh9	668	3	in	in	IN
cord-008530-yni0poh9	668	4	the	the	DT
cord-008530-yni0poh9	668	5	brain	brain	NN
cord-008530-yni0poh9	668	6	:	:	:
cord-008530-yni0poh9	668	7	does	do	VBZ
cord-008530-yni0poh9	668	8	the	the	DT
cord-008530-yni0poh9	668	9	CNS	CNS	NNP
cord-008530-yni0poh9	668	10	shape	shape	NN
cord-008530-yni0poh9	668	11	immune	immune	JJ
cord-008530-yni0poh9	668	12	responses	response	NNS
cord-008530-yni0poh9	668	13	?	?	.
cord-008530-yni0poh9	669	1	Neurotactin	Neurotactin	NNP
cord-008530-yni0poh9	669	2	,	,	,
cord-008530-yni0poh9	669	3	a	a	DT
cord-008530-yni0poh9	669	4	membrane	membrane	NN
cord-008530-yni0poh9	669	5	-	-	HYPH
cord-008530-yni0poh9	669	6	anchored	anchor	VBN
cord-008530-yni0poh9	669	7	chemokine	chemokine	NN
cord-008530-yni0poh9	669	8	upregulated	upregulate	VBN
cord-008530-yni0poh9	669	9	in	in	IN
cord-008530-yni0poh9	669	10	brain	brain	NN
cord-008530-yni0poh9	669	11	inflammation	inflammation	NN
cord-008530-yni0poh9	669	12	Cytomegalovirus	Cytomegalovirus	NNP
cord-008530-yni0poh9	669	13	encodes	encode	VBZ
cord-008530-yni0poh9	669	14	a	a	DT
cord-008530-yni0poh9	669	15	potent	potent	JJ
cord-008530-yni0poh9	669	16	alpha	alpha	NN
cord-008530-yni0poh9	669	17	chemokine	chemokine	NN
cord-008530-yni0poh9	669	18	Identification	identification	NN
cord-008530-yni0poh9	669	19	of	of	IN
cord-008530-yni0poh9	669	20	a	a	DT
cord-008530-yni0poh9	669	21	chemokine	chemokine	NN
cord-008530-yni0poh9	669	22	receptor	receptor	NN
cord-008530-yni0poh9	669	23	encoded	encode	VBN
cord-008530-yni0poh9	669	24	by	by	IN
cord-008530-yni0poh9	669	25	human	human	JJ
cord-008530-yni0poh9	669	26	cytomegalovirus	cytomegalovirus	NN
cord-008530-yni0poh9	669	27	as	as	IN
cord-008530-yni0poh9	669	28	a	a	DT
cord-008530-yni0poh9	669	29	cofacter	cofacter	NN
cord-008530-yni0poh9	669	30	for	for	IN
cord-008530-yni0poh9	669	31	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	669	32	entry	entry	NN
cord-008530-yni0poh9	669	33	Developmental	developmental	JJ
cord-008530-yni0poh9	669	34	expression	expression	NN
cord-008530-yni0poh9	669	35	of	of	IN
cord-008530-yni0poh9	669	36	cytokine	cytokine	JJ
cord-008530-yni0poh9	669	37	genes	gene	NNS
cord-008530-yni0poh9	669	38	in	in	IN
cord-008530-yni0poh9	669	39	the	the	DT
cord-008530-yni0poh9	669	40	cortex	cortex	NN
cord-008530-yni0poh9	669	41	and	and	CC
cord-008530-yni0poh9	669	42	hippocampus	hippocampus	NN
cord-008530-yni0poh9	669	43	of	of	IN
cord-008530-yni0poh9	669	44	the	the	DT
cord-008530-yni0poh9	669	45	rat	rat	NN
cord-008530-yni0poh9	669	46	central	central	JJ
cord-008530-yni0poh9	669	47	nervous	nervous	JJ
cord-008530-yni0poh9	669	48	system	system	NN
cord-008530-yni0poh9	670	1	Demented	demented	JJ
cord-008530-yni0poh9	670	2	and	and	CC
cord-008530-yni0poh9	670	3	non	non	JJ
cord-008530-yni0poh9	670	4	-	-	JJ
cord-008530-yni0poh9	670	5	demented	demented	JJ
cord-008530-yni0poh9	670	6	patients	patient	NNS
cord-008530-yni0poh9	670	7	with	with	IN
cord-008530-yni0poh9	670	8	AIDS	AIDS	NNP
cord-008530-yni0poh9	670	9	differ	differ	VBP
cord-008530-yni0poh9	670	10	in	in	IN
cord-008530-yni0poh9	670	11	brainderived	brainderived	JJ
cord-008530-yni0poh9	670	12	human	human	JJ
cord-008530-yni0poh9	670	13	immunodeficiency	immunodeficiency	NNP
cord-008530-yni0poh9	670	14	virus	virus	NN
cord-008530-yni0poh9	670	15	type	type	NN
cord-008530-yni0poh9	670	16	1	1	CD
cord-008530-yni0poh9	670	17	envelope	envelope	NN
cord-008530-yni0poh9	670	18	sequences	sequence	NNS
cord-008530-yni0poh9	670	19	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	670	20	receptors	receptor	NNS
cord-008530-yni0poh9	670	21	:	:	:
cord-008530-yni0poh9	670	22	gateways	gateway	NNS
cord-008530-yni0poh9	670	23	to	to	IN
cord-008530-yni0poh9	670	24	inflammation	inflammation	NN
cord-008530-yni0poh9	670	25	and	and	CC
cord-008530-yni0poh9	670	26	infection	infection	NN
cord-008530-yni0poh9	671	1	The	the	DT
cord-008530-yni0poh9	671	2	chemokine	chemokine	NN
cord-008530-yni0poh9	671	3	receptors	receptor	NNS
cord-008530-yni0poh9	672	1	CXCR3	CXCR3	NNP
cord-008530-yni0poh9	672	2	and	and	CC
cord-008530-yni0poh9	673	1	CCR5	ccr5	JJ
cord-008530-yni0poh9	673	2	mark	mark	NN
cord-008530-yni0poh9	673	3	subsets	subset	NNS
cord-008530-yni0poh9	673	4	of	of	IN
cord-008530-yni0poh9	673	5	T	t	NN
cord-008530-yni0poh9	673	6	cells	cell	NNS
cord-008530-yni0poh9	673	7	associated	associate	VBN
cord-008530-yni0poh9	673	8	with	with	IN
cord-008530-yni0poh9	673	9	certain	certain	JJ
cord-008530-yni0poh9	673	10	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	673	11	reactions	reaction	NNS
cord-008530-yni0poh9	673	12	Morphological	morphological	JJ
cord-008530-yni0poh9	673	13	correlates	correlate	NNS
cord-008530-yni0poh9	673	14	of	of	IN
cord-008530-yni0poh9	673	15	neurological	neurological	JJ
cord-008530-yni0poh9	673	16	dyshmction	dyshmction	NN
cord-008530-yni0poh9	673	17	in	in	IN
cord-008530-yni0poh9	673	18	macaques	macaque	NNS
cord-008530-yni0poh9	673	19	infected	infect	VBN
cord-008530-yni0poh9	673	20	with	with	IN
cord-008530-yni0poh9	673	21	neurovirulent	neurovirulent	NNP
cord-008530-yni0poh9	673	22	simian	simian	JJ
cord-008530-yni0poh9	673	23	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	673	24	virus	virus	NN
cord-008530-yni0poh9	674	1	The	the	DT
cord-008530-yni0poh9	674	2	role	role	NN
cord-008530-yni0poh9	674	3	of	of	IN
cord-008530-yni0poh9	674	4	CCR7	CCR7	NNP
cord-008530-yni0poh9	674	5	in	in	IN
cord-008530-yni0poh9	674	6	T(H)I	T(H)I	NNP
cord-008530-yni0poh9	674	7	and	and	CC
cord-008530-yni0poh9	674	8	T(H)2	t(h)2	JJ
cord-008530-yni0poh9	674	9	cell	cell	NN
cord-008530-yni0poh9	674	10	localization	localization	NN
cord-008530-yni0poh9	674	11	and	and	CC
cord-008530-yni0poh9	674	12	delivery	delivery	NN
cord-008530-yni0poh9	674	13	of	of	IN
cord-008530-yni0poh9	674	14	B	b	NN
cord-008530-yni0poh9	674	15	cell	cell	NN
cord-008530-yni0poh9	674	16	help	help	NN
cord-008530-yni0poh9	674	17	in	in	IN
cord-008530-yni0poh9	674	18	vivo	vivo	NNP
cord-008530-yni0poh9	674	19	Chemokines	Chemokines	NNP
cord-008530-yni0poh9	674	20	in	in	IN
cord-008530-yni0poh9	674	21	neurological	neurological	JJ
cord-008530-yni0poh9	674	22	disease	disease	NN
cord-008530-yni0poh9	674	23	models	model	NNS
cord-008530-yni0poh9	674	24	:	:	:
cord-008530-yni0poh9	674	25	correlation	correlation	NN
cord-008530-yni0poh9	674	26	between	between	IN
cord-008530-yni0poh9	674	27	chemokine	chemokine	JJ
cord-008530-yni0poh9	674	28	expression	expression	NN
cord-008530-yni0poh9	674	29	patterns	pattern	NNS
cord-008530-yni0poh9	674	30	and	and	CC
cord-008530-yni0poh9	674	31	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	674	32	pathology	pathology	NN
cord-008530-yni0poh9	675	1	Do	do	VBP
cord-008530-yni0poh9	675	2	chemokines	chemokine	NNS
cord-008530-yni0poh9	675	3	mediate	mediate	VB
cord-008530-yni0poh9	675	4	leukocyte	leukocyte	NN
cord-008530-yni0poh9	675	5	recruitment	recruitment	NN
cord-008530-yni0poh9	675	6	in	in	IN
cord-008530-yni0poh9	675	7	post	post	JJ
cord-008530-yni0poh9	675	8	-	-	JJ
cord-008530-yni0poh9	675	9	traumatic	traumatic	JJ
cord-008530-yni0poh9	675	10	CNS	CNS	NNP
cord-008530-yni0poh9	675	11	inflammation	inflammation	NN
cord-008530-yni0poh9	675	12	?	?	.
cord-008530-yni0poh9	676	1	The	the	DT
cord-008530-yni0poh9	676	2	orphan	orphan	NN
cord-008530-yni0poh9	676	3	G	g	NN
cord-008530-yni0poh9	676	4	-	-	HYPH
cord-008530-yni0poh9	676	5	protein	protein	NN
cord-008530-yni0poh9	676	6	-	-	HYPH
cord-008530-yni0poh9	676	7	coupled	couple	VBN
cord-008530-yni0poh9	676	8	recepter	recepter	NN
cord-008530-yni0poh9	676	9	-	-	HYPH
cord-008530-yni0poh9	676	10	encoding	encoding	NN
cord-008530-yni0poh9	676	11	gene	gene	NN
cord-008530-yni0poh9	676	12	V28	V28	NNP
cord-008530-yni0poh9	676	13	is	be	VBZ
cord-008530-yni0poh9	676	14	closely	closely	RB
cord-008530-yni0poh9	676	15	related	relate	VBN
cord-008530-yni0poh9	676	16	to	to	IN
cord-008530-yni0poh9	676	17	genes	gene	NNS
cord-008530-yni0poh9	676	18	for	for	IN
cord-008530-yni0poh9	676	19	chemokine	chemokine	NN
cord-008530-yni0poh9	676	20	receptors	receptor	NNS
cord-008530-yni0poh9	676	21	and	and	CC
cord-008530-yni0poh9	676	22	is	be	VBZ
cord-008530-yni0poh9	676	23	expressed	express	VBN
cord-008530-yni0poh9	676	24	in	in	IN
cord-008530-yni0poh9	676	25	lymphoid	lymphoid	JJ
cord-008530-yni0poh9	676	26	and	and	CC
cord-008530-yni0poh9	676	27	neural	neural	JJ
cord-008530-yni0poh9	676	28	tissues	tissue	NNS
cord-008530-yni0poh9	676	29	Lipopolysaccharide	Lipopolysaccharide	NNP
cord-008530-yni0poh9	676	30	-	-	HYPH
cord-008530-yni0poh9	676	31	induced	induce	VBN
cord-008530-yni0poh9	676	32	expression	expression	NN
cord-008530-yni0poh9	676	33	of	of	IN
cord-008530-yni0poh9	676	34	IP-10	IP-10	NNP
cord-008530-yni0poh9	676	35	mRNA	mRNA	NNP
cord-008530-yni0poh9	676	36	in	in	IN
cord-008530-yni0poh9	676	37	rat	rat	NN
cord-008530-yni0poh9	676	38	brain	brain	NN
cord-008530-yni0poh9	676	39	and	and	CC
cord-008530-yni0poh9	676	40	in	in	IN
cord-008530-yni0poh9	676	41	cultured	cultured	JJ
cord-008530-yni0poh9	676	42	rat	rat	NN
cord-008530-yni0poh9	676	43	astroeytes	astroeytes	NNP
cord-008530-yni0poh9	676	44	and	and	CC
cord-008530-yni0poh9	676	45	mieroglia	mieroglia	NNP
cord-008530-yni0poh9	676	46	.	.	.
cord-008530-yni0poh9	677	1	Molec	Molec	NNP
cord-008530-yni0poh9	677	2	Time	Time	NNP
cord-008530-yni0poh9	677	3	course	course	NN
cord-008530-yni0poh9	677	4	of	of	IN
cord-008530-yni0poh9	677	5	chemokines	chemokine	NNS
cord-008530-yni0poh9	677	6	in	in	IN
cord-008530-yni0poh9	677	7	the	the	DT
cord-008530-yni0poh9	677	8	cerebrospinal	cerebrospinal	JJ
cord-008530-yni0poh9	677	9	fluid	fluid	NN
cord-008530-yni0poh9	677	10	and	and	CC
cord-008530-yni0poh9	677	11	serum	serum	NN
cord-008530-yni0poh9	677	12	during	during	IN
cord-008530-yni0poh9	677	13	herpes	herpes	NNP
cord-008530-yni0poh9	677	14	simplex	simplex	NNP
cord-008530-yni0poh9	677	15	type	type	NN
cord-008530-yni0poh9	677	16	i	i	PRP
cord-008530-yni0poh9	677	17	encephalitis	encephalitis	RB
cord-008530-yni0poh9	677	18	Cytomegalovirus	Cytomegalovirus	NNP
cord-008530-yni0poh9	677	19	-	-	HYPH
cord-008530-yni0poh9	677	20	encoded	encode	VBN
cord-008530-yni0poh9	677	21	beta	beta	NN
cord-008530-yni0poh9	677	22	chemokine	chemokine	NN
cord-008530-yni0poh9	677	23	promotes	promote	VBZ
cord-008530-yni0poh9	677	24	monocyte	monocyte	NNP
cord-008530-yni0poh9	677	25	-	-	HYPH
cord-008530-yni0poh9	677	26	associated	associate	VBN
cord-008530-yni0poh9	677	27	viremia	viremia	NN
cord-008530-yni0poh9	677	28	in	in	IN
cord-008530-yni0poh9	677	29	the	the	DT
cord-008530-yni0poh9	677	30	host	host	NN
cord-008530-yni0poh9	677	31	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	677	32	and	and	CC
cord-008530-yni0poh9	677	33	chemokine	chemokine	NN
cord-008530-yni0poh9	677	34	receptors	receptor	NNS
cord-008530-yni0poh9	677	35	in	in	IN
cord-008530-yni0poh9	677	36	T	t	NN
cord-008530-yni0poh9	677	37	-	-	HYPH
cord-008530-yni0poh9	677	38	cell	cell	NN
cord-008530-yni0poh9	677	39	priming	priming	NN
cord-008530-yni0poh9	677	40	and	and	CC
cord-008530-yni0poh9	677	41	Thl	Thl	NNP
cord-008530-yni0poh9	677	42	/	/	SYM
cord-008530-yni0poh9	677	43	Th2-mediated	Th2-mediated	NNP
cord-008530-yni0poh9	677	44	responses	response	NNS
cord-008530-yni0poh9	678	1	Two	two	CD
cord-008530-yni0poh9	678	2	subsets	subset	NNS
cord-008530-yni0poh9	678	3	of	of	IN
cord-008530-yni0poh9	678	4	memory	memory	NN
cord-008530-yni0poh9	678	5	T	t	NN
cord-008530-yni0poh9	678	6	lymphocytes	lymphocyte	NNS
cord-008530-yni0poh9	678	7	with	with	IN
cord-008530-yni0poh9	678	8	distinct	distinct	JJ
cord-008530-yni0poh9	678	9	homing	homing	NN
cord-008530-yni0poh9	678	10	potentials	potential	NNS
cord-008530-yni0poh9	678	11	and	and	CC
cord-008530-yni0poh9	678	12	effecter	effecter	NN
cord-008530-yni0poh9	678	13	functions	function	NNS
cord-008530-yni0poh9	678	14	Selective	selective	JJ
cord-008530-yni0poh9	678	15	expression	expression	NN
cord-008530-yni0poh9	678	16	of	of	IN
cord-008530-yni0poh9	678	17	the	the	DT
cord-008530-yni0poh9	678	18	eotaxin	eotaxin	NNP
cord-008530-yni0poh9	678	19	receptor	receptor	NN
cord-008530-yni0poh9	678	20	CCR3	CCR3	NNP
cord-008530-yni0poh9	678	21	by	by	IN
cord-008530-yni0poh9	678	22	human	human	JJ
cord-008530-yni0poh9	678	23	T	T	NNP
cord-008530-yni0poh9	678	24	helper	helper	NN
cord-008530-yni0poh9	678	25	2	2	CD
cord-008530-yni0poh9	678	26	cells	cell	NNS
cord-008530-yni0poh9	678	27	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	678	28	and	and	CC
cord-008530-yni0poh9	678	29	receptors	receptor	NNS
cord-008530-yni0poh9	678	30	in	in	IN
cord-008530-yni0poh9	678	31	HIV	HIV	NNP
cord-008530-yni0poh9	678	32	encephalitis	encephalitis	NNP
cord-008530-yni0poh9	678	33	Neuropathogenesis	Neuropathogenesis	NNP
cord-008530-yni0poh9	678	34	of	of	IN
cord-008530-yni0poh9	678	35	simian	simian	NNP
cord-008530-yni0poh9	678	36	immunodeflcieney	immunodeflcieney	NNP
cord-008530-yni0poh9	678	37	virus	virus	NN
cord-008530-yni0poh9	678	38	infection	infection	NN
cord-008530-yni0poh9	678	39	in	in	IN
cord-008530-yni0poh9	678	40	macaque	macaque	NN
cord-008530-yni0poh9	678	41	monkeys	monkey	NNS
cord-008530-yni0poh9	678	42	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	678	43	expression	expression	NN
cord-008530-yni0poh9	678	44	in	in	IN
cord-008530-yni0poh9	678	45	simian	simian	JJ
cord-008530-yni0poh9	678	46	immunodefieieney	immunodefieieney	NN
cord-008530-yni0poh9	678	47	virus	virus	NN
cord-008530-yni0poh9	678	48	-	-	HYPH
cord-008530-yni0poh9	678	49	induced	induce	VBN
cord-008530-yni0poh9	678	50	AIDS	AIDS	NNP
cord-008530-yni0poh9	678	51	encephalitis	encephalitis	NNP
cord-008530-yni0poh9	678	52	Human	Human	NNP
cord-008530-yni0poh9	678	53	immunodeflciency	immunodeflciency	NNP
cord-008530-yni0poh9	678	54	virus	virus	NN
cord-008530-yni0poh9	678	55	type	type	NN
cord-008530-yni0poh9	678	56	I	-PRON-	PRP
cord-008530-yni0poh9	678	57	infection	infection	NN
cord-008530-yni0poh9	678	58	alters	alter	VBZ
cord-008530-yni0poh9	678	59	chemokine	chemokine	NN
cord-008530-yni0poh9	678	60	beta	beta	JJ
cord-008530-yni0poh9	678	61	peptide	peptide	JJ
cord-008530-yni0poh9	678	62	expression	expression	NN
cord-008530-yni0poh9	678	63	in	in	IN
cord-008530-yni0poh9	678	64	human	human	JJ
cord-008530-yni0poh9	678	65	monocytes	monocyte	NNS
cord-008530-yni0poh9	678	66	--	--	:
cord-008530-yni0poh9	678	67	implications	implication	NNS
cord-008530-yni0poh9	678	68	for	for	IN
cord-008530-yni0poh9	678	69	recruitment	recruitment	NN
cord-008530-yni0poh9	678	70	of	of	IN
cord-008530-yni0poh9	678	71	leukocytes	leukocyte	NNS
cord-008530-yni0poh9	678	72	into	into	IN
cord-008530-yni0poh9	678	73	brain	brain	NN
cord-008530-yni0poh9	678	74	and	and	CC
cord-008530-yni0poh9	678	75	lymph	lymph	NN
cord-008530-yni0poh9	678	76	nodes	node	NNS
cord-008530-yni0poh9	679	1	Neuronal	neuronal	JJ
cord-008530-yni0poh9	679	2	expression	expression	NN
cord-008530-yni0poh9	679	3	of	of	IN
cord-008530-yni0poh9	679	4	fractalkine	fractalkine	NN
cord-008530-yni0poh9	679	5	in	in	IN
cord-008530-yni0poh9	679	6	the	the	DT
cord-008530-yni0poh9	679	7	presence	presence	NN
cord-008530-yni0poh9	679	8	and	and	CC
cord-008530-yni0poh9	679	9	absence	absence	NN
cord-008530-yni0poh9	679	10	of	of	IN
cord-008530-yni0poh9	679	11	inflammation	inflammation	NN
cord-008530-yni0poh9	679	12	Genome	genome	NN
cord-008530-yni0poh9	679	13	sequence	sequence	NN
cord-008530-yni0poh9	679	14	of	of	IN
cord-008530-yni0poh9	679	15	a	a	DT
cord-008530-yni0poh9	679	16	human	human	JJ
cord-008530-yni0poh9	679	17	tumorigenic	tumorigenic	NNP
cord-008530-yni0poh9	679	18	poxvirus	poxvirus	NNP
cord-008530-yni0poh9	679	19	:	:	:
cord-008530-yni0poh9	679	20	prediction	prediction	NN
cord-008530-yni0poh9	679	21	of	of	IN
cord-008530-yni0poh9	679	22	specific	specific	JJ
cord-008530-yni0poh9	679	23	host	host	NN
cord-008530-yni0poh9	679	24	response	response	NN
cord-008530-yni0poh9	679	25	-	-	HYPH
cord-008530-yni0poh9	679	26	evasion	evasion	NN
cord-008530-yni0poh9	679	27	genes	gene	NNS
cord-008530-yni0poh9	679	28	Apoptosis	Apoptosis	NNP
cord-008530-yni0poh9	679	29	induced	induce	VBN
cord-008530-yni0poh9	679	30	by	by	IN
cord-008530-yni0poh9	679	31	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	679	32	infection	infection	NN
cord-008530-yni0poh9	679	33	of	of	IN
cord-008530-yni0poh9	679	34	the	the	DT
cord-008530-yni0poh9	679	35	central	central	JJ
cord-008530-yni0poh9	679	36	nervous	nervous	JJ
cord-008530-yni0poh9	679	37	system	system	NN
cord-008530-yni0poh9	679	38	Structure	Structure	NNP
cord-008530-yni0poh9	679	39	and	and	CC
cord-008530-yni0poh9	679	40	chromosomal	chromosomal	JJ
cord-008530-yni0poh9	679	41	localization	localization	NN
cord-008530-yni0poh9	679	42	of	of	IN
cord-008530-yni0poh9	679	43	the	the	DT
cord-008530-yni0poh9	679	44	human	human	JJ
cord-008530-yni0poh9	679	45	stromal	stromal	NN
cord-008530-yni0poh9	679	46	cell	cell	NN
cord-008530-yni0poh9	679	47	-	-	HYPH
cord-008530-yni0poh9	679	48	derived	derive	VBN
cord-008530-yni0poh9	679	49	factor	factor	NN
cord-008530-yni0poh9	679	50	1	1	CD
cord-008530-yni0poh9	680	1	(	(	-LRB-
cord-008530-yni0poh9	680	2	SDF1	SDF1	NNP
cord-008530-yni0poh9	680	3	)	)	-RRB-
cord-008530-yni0poh9	680	4	gene	gene	NN
cord-008530-yni0poh9	680	5	Expression	expression	NN
cord-008530-yni0poh9	680	6	of	of	IN
cord-008530-yni0poh9	680	7	monocyte	monocyte	NNP
cord-008530-yni0poh9	680	8	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	680	9	protein-1	protein-1	NNP
cord-008530-yni0poh9	680	10	and	and	CC
cord-008530-yni0poh9	680	11	other	other	JJ
cord-008530-yni0poh9	680	12	~-chemokines	~-chemokine	NNS
cord-008530-yni0poh9	680	13	by	by	IN
cord-008530-yni0poh9	680	14	resident	resident	NN
cord-008530-yni0poh9	680	15	glia	glia	NNS
cord-008530-yni0poh9	680	16	and	and	CC
cord-008530-yni0poh9	680	17	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	680	18	cells	cell	NNS
cord-008530-yni0poh9	680	19	in	in	IN
cord-008530-yni0poh9	680	20	multiple	multiple	JJ
cord-008530-yni0poh9	680	21	sclerosis	sclerosis	NN
cord-008530-yni0poh9	680	22	lesions	lesion	NNS
cord-008530-yni0poh9	680	23	Vaccinia	Vaccinia	NNP
cord-008530-yni0poh9	680	24	virus	virus	NN
cord-008530-yni0poh9	680	25	immune	immune	JJ
cord-008530-yni0poh9	680	26	evasion	evasion	NN
cord-008530-yni0poh9	680	27	Expression	expression	NN
cord-008530-yni0poh9	680	28	of	of	IN
cord-008530-yni0poh9	680	29	specific	specific	JJ
cord-008530-yni0poh9	680	30	chemokines	chemokine	NNS
cord-008530-yni0poh9	680	31	and	and	CC
cord-008530-yni0poh9	680	32	chemokine	chemokine	NN
cord-008530-yni0poh9	680	33	receptors	receptor	NNS
cord-008530-yni0poh9	680	34	in	in	IN
cord-008530-yni0poh9	680	35	the	the	DT
cord-008530-yni0poh9	680	36	central	central	JJ
cord-008530-yni0poh9	680	37	nervous	nervous	JJ
cord-008530-yni0poh9	680	38	system	system	NN
cord-008530-yni0poh9	680	39	of	of	IN
cord-008530-yni0poh9	680	40	multiple	multiple	JJ
cord-008530-yni0poh9	680	41	sclerosis	sclerosis	NN
cord-008530-yni0poh9	680	42	patients	patient	NNS
cord-008530-yni0poh9	681	1	The	the	DT
cord-008530-yni0poh9	681	2	C	C	NNP
cord-008530-yni0poh9	681	3	-	-	HYPH
cord-008530-yni0poh9	681	4	C	C	NNP
cord-008530-yni0poh9	681	5	chemokine	chemokine	NN
cord-008530-yni0poh9	681	6	6Ckine	6Ckine	NNP
cord-008530-yni0poh9	681	7	binds	bind	VBZ
cord-008530-yni0poh9	681	8	the	the	DT
cord-008530-yni0poh9	681	9	CXC	CXC	NNP
cord-008530-yni0poh9	681	10	chemokine	chemokine	NN
cord-008530-yni0poh9	681	11	receptor	receptor	NN
cord-008530-yni0poh9	681	12	CXCR3	cxcr3	XX
cord-008530-yni0poh9	682	1	The	the	DT
cord-008530-yni0poh9	682	2	viral	viral	JJ
cord-008530-yni0poh9	682	3	chemokine	chemokine	NN
cord-008530-yni0poh9	682	4	macrophage	macrophage	NN
cord-008530-yni0poh9	682	5	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	682	6	protein	protein	NN
cord-008530-yni0poh9	682	7	-	-	HYPH
cord-008530-yni0poh9	682	8	II	II	NNP
cord-008530-yni0poh9	682	9	is	be	VBZ
cord-008530-yni0poh9	682	10	a	a	DT
cord-008530-yni0poh9	682	11	selective	selective	JJ
cord-008530-yni0poh9	682	12	Th2	Th2	NNP
cord-008530-yni0poh9	682	13	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	682	14	C	C	NNP
cord-008530-yni0poh9	682	15	-	-	HYPH
cord-008530-yni0poh9	682	16	X	X	NNP
cord-008530-yni0poh9	682	17	-	-	HYPH
cord-008530-yni0poh9	682	18	C	C	NNP
cord-008530-yni0poh9	682	19	and	and	CC
cord-008530-yni0poh9	682	20	C	C	NNP
cord-008530-yni0poh9	682	21	-	-	HYPH
cord-008530-yni0poh9	682	22	C	C	NNP
cord-008530-yni0poh9	682	23	chemokines	chemokine	NNS
cord-008530-yni0poh9	682	24	are	be	VBP
cord-008530-yni0poh9	682	25	expressed	express	VBN
cord-008530-yni0poh9	682	26	in	in	IN
cord-008530-yni0poh9	682	27	the	the	DT
cord-008530-yni0poh9	682	28	cerebrospinal	cerebrospinal	JJ
cord-008530-yni0poh9	682	29	fluid	fluid	NN
cord-008530-yni0poh9	682	30	in	in	IN
cord-008530-yni0poh9	682	31	bacterial	bacterial	JJ
cord-008530-yni0poh9	682	32	meningitis	meningitis	NN
cord-008530-yni0poh9	682	33	and	and	CC
cord-008530-yni0poh9	682	34	mediate	mediate	VB
cord-008530-yni0poh9	682	35	chemotactic	chemotactic	JJ
cord-008530-yni0poh9	682	36	activity	activity	NN
cord-008530-yni0poh9	682	37	on	on	IN
cord-008530-yni0poh9	682	38	peripheral	peripheral	JJ
cord-008530-yni0poh9	682	39	blood	blood	NN
cord-008530-yni0poh9	682	40	-	-	HYPH
cord-008530-yni0poh9	682	41	derived	derive	VBN
cord-008530-yni0poh9	682	42	polymorphonuclear	polymorphonuclear	JJ
cord-008530-yni0poh9	682	43	and	and	CC
cord-008530-yni0poh9	682	44	mononuclear	mononuclear	NN
cord-008530-yni0poh9	682	45	cells	cell	NNS
cord-008530-yni0poh9	682	46	in	in	IN
cord-008530-yni0poh9	682	47	vitro	vitro	FW
cord-008530-yni0poh9	682	48	Cloning	cloning	NN
cord-008530-yni0poh9	682	49	of	of	IN
cord-008530-yni0poh9	682	50	rat	rat	NN
cord-008530-yni0poh9	682	51	HIV	HIV	NNP
cord-008530-yni0poh9	682	52	-	-	HYPH
cord-008530-yni0poh9	682	53	l	l	NNP
cord-008530-yni0poh9	682	54	-	-	HYPH
cord-008530-yni0poh9	682	55	chemokine	chemokine	NN
cord-008530-yni0poh9	682	56	coreceptor	coreceptor	NN
cord-008530-yni0poh9	682	57	CKR5	CKR5	NNP
cord-008530-yni0poh9	682	58	from	from	IN
cord-008530-yni0poh9	682	59	microglia	microglia	NN
cord-008530-yni0poh9	682	60	and	and	CC
cord-008530-yni0poh9	682	61	upregulation	upregulation	NN
cord-008530-yni0poh9	682	62	of	of	IN
cord-008530-yni0poh9	682	63	its	-PRON-	PRP$
cord-008530-yni0poh9	682	64	mRNA	mrna	NN
cord-008530-yni0poh9	682	65	in	in	IN
cord-008530-yni0poh9	682	66	ischemic	ischemic	NNP
cord-008530-yni0poh9	682	67	and	and	CC
cord-008530-yni0poh9	682	68	endotoxinemic	endotoxinemic	NNP
cord-008530-yni0poh9	682	69	rat	rat	NNP
cord-008530-yni0poh9	682	70	brain	brain	NNP
cord-008530-yni0poh9	682	71	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	682	72	in	in	IN
cord-008530-yni0poh9	682	73	the	the	DT
cord-008530-yni0poh9	682	74	cerebrospinal	cerebrospinal	JJ
cord-008530-yni0poh9	682	75	fluid	fluid	NN
cord-008530-yni0poh9	682	76	patients	patient	NNS
cord-008530-yni0poh9	682	77	with	with	IN
cord-008530-yni0poh9	682	78	meningitis	meningitis	NN
cord-008530-yni0poh9	682	79	Virally	Virally	NNP
cord-008530-yni0poh9	682	80	encoded	encode	VBD
cord-008530-yni0poh9	682	81	chemokines	chemokine	NNS
cord-008530-yni0poh9	682	82	and	and	CC
cord-008530-yni0poh9	682	83	chemokine	chemokine	NN
cord-008530-yni0poh9	682	84	receptors	receptor	NNS
cord-008530-yni0poh9	682	85	:	:	:
cord-008530-yni0poh9	682	86	genetic	genetic	JJ
cord-008530-yni0poh9	682	87	embezzlement	embezzlement	NN
cord-008530-yni0poh9	682	88	of	of	IN
cord-008530-yni0poh9	682	89	host	host	NN
cord-008530-yni0poh9	682	90	DNA	dna	NN
cord-008530-yni0poh9	683	1	The	the	DT
cord-008530-yni0poh9	683	2	role	role	NN
cord-008530-yni0poh9	683	3	of	of	IN
cord-008530-yni0poh9	683	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	683	5	in	in	IN
cord-008530-yni0poh9	683	6	models	model	NNS
cord-008530-yni0poh9	683	7	of	of	IN
cord-008530-yni0poh9	683	8	human	human	JJ
cord-008530-yni0poh9	683	9	disease	disease	NN
cord-008530-yni0poh9	684	1	The	the	DT
cord-008530-yni0poh9	684	2	chemokine	chemokine	NN
cord-008530-yni0poh9	684	3	receptor	receptor	NN
cord-008530-yni0poh9	684	4	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	684	5	is	be	VBZ
cord-008530-yni0poh9	684	6	essential	essential	JJ
cord-008530-yni0poh9	684	7	for	for	IN
cord-008530-yni0poh9	684	8	vascularization	vascularization	NN
cord-008530-yni0poh9	684	9	of	of	IN
cord-008530-yni0poh9	684	10	the	the	DT
cord-008530-yni0poh9	684	11	gastrointestinal	gastrointestinal	JJ
cord-008530-yni0poh9	684	12	tract	tract	NN
cord-008530-yni0poh9	684	13	Murine	Murine	NNP
cord-008530-yni0poh9	684	14	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	684	15	express	express	VBP
cord-008530-yni0poh9	684	16	a	a	DT
cord-008530-yni0poh9	684	17	fimctional	fimctional	JJ
cord-008530-yni0poh9	684	18	chemokine	chemokine	NN
cord-008530-yni0poh9	684	19	receptor	receptor	NN
cord-008530-yni0poh9	684	20	Functional	functional	JJ
cord-008530-yni0poh9	684	21	expression	expression	NN
cord-008530-yni0poh9	684	22	of	of	IN
cord-008530-yni0poh9	684	23	the	the	DT
cord-008530-yni0poh9	684	24	CXCchemokine	cxcchemokine	NN
cord-008530-yni0poh9	684	25	receptor-4	receptor-4	NNP
cord-008530-yni0poh9	684	26	/	/	,
cord-008530-yni0poh9	684	27	fusin	fusin	NNP
cord-008530-yni0poh9	684	28	on	on	IN
cord-008530-yni0poh9	684	29	mouse	mouse	NN
cord-008530-yni0poh9	684	30	microglial	microglial	JJ
cord-008530-yni0poh9	684	31	cells	cell	NNS
cord-008530-yni0poh9	684	32	and	and	CC
cord-008530-yni0poh9	684	33	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	684	34	Neutrophil	Neutrophil	NNP
cord-008530-yni0poh9	684	35	infiltration	infiltration	NN
cord-008530-yni0poh9	684	36	,	,	,
cord-008530-yni0poh9	684	37	glial	glial	JJ
cord-008530-yni0poh9	684	38	reaction	reaction	NN
cord-008530-yni0poh9	684	39	,	,	,
cord-008530-yni0poh9	684	40	and	and	CC
cord-008530-yni0poh9	684	41	neurological	neurological	JJ
cord-008530-yni0poh9	684	42	disease	disease	NN
cord-008530-yni0poh9	684	43	in	in	IN
cord-008530-yni0poh9	684	44	transgenic	transgenic	JJ
cord-008530-yni0poh9	684	45	mice	mouse	NNS
cord-008530-yni0poh9	684	46	expressing	express	VBG
cord-008530-yni0poh9	684	47	the	the	DT
cord-008530-yni0poh9	684	48	chemokine	chemokine	NN
cord-008530-yni0poh9	684	49	N51	N51	NNP
cord-008530-yni0poh9	684	50	/	/	SYM
cord-008530-yni0poh9	684	51	KC	KC	NNP
cord-008530-yni0poh9	684	52	in	in	IN
cord-008530-yni0poh9	684	53	oligodendrocytes	oligodendrocyte	NNS
cord-008530-yni0poh9	684	54	Signal	Signal	NNP
cord-008530-yni0poh9	684	55	sequence	sequence	NN
cord-008530-yni0poh9	684	56	trap	trap	NN
cord-008530-yni0poh9	684	57	:	:	:
cord-008530-yni0poh9	684	58	a	a	DT
cord-008530-yni0poh9	684	59	cloning	clone	VBG
cord-008530-yni0poh9	684	60	strategy	strategy	NN
cord-008530-yni0poh9	684	61	for	for	IN
cord-008530-yni0poh9	684	62	secreted	secrete	VBN
cord-008530-yni0poh9	684	63	proteins	protein	NNS
cord-008530-yni0poh9	684	64	and	and	CC
cord-008530-yni0poh9	684	65	type	type	NN
cord-008530-yni0poh9	684	66	I	-PRON-	PRP
cord-008530-yni0poh9	684	67	membrane	membrane	NN
cord-008530-yni0poh9	684	68	proteins	protein	NNS
cord-008530-yni0poh9	684	69	Chemokines	Chemokines	NNPS
cord-008530-yni0poh9	684	70	,	,	,
cord-008530-yni0poh9	684	71	inflammation	inflammation	NN
cord-008530-yni0poh9	684	72	and	and	CC
cord-008530-yni0poh9	684	73	the	the	DT
cord-008530-yni0poh9	684	74	immune	immune	JJ
cord-008530-yni0poh9	684	75	system	system	NN
cord-008530-yni0poh9	684	76	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	684	77	infection	infection	NN
cord-008530-yni0poh9	684	78	in	in	IN
cord-008530-yni0poh9	684	79	an	an	DT
cord-008530-yni0poh9	684	80	individual	individual	JJ
cord-008530-yni0poh9	684	81	homozygous	homozygous	JJ
cord-008530-yni0poh9	684	82	for	for	IN
cord-008530-yni0poh9	684	83	CCR5	CCR5	NNP
cord-008530-yni0poh9	684	84	delta	delta	NN
cord-008530-yni0poh9	684	85	32	32	CD
cord-008530-yni0poh9	684	86	Herpes	Herpes	NNP
cord-008530-yni0poh9	684	87	simplex	simplex	NN
cord-008530-yni0poh9	684	88	virus	virus	NN
cord-008530-yni0poh9	684	89	replicationinduced	replicationinduce	VBN
cord-008530-yni0poh9	684	90	expression	expression	NN
cord-008530-yni0poh9	684	91	of	of	IN
cord-008530-yni0poh9	684	92	chemokines	chemokine	NNS
cord-008530-yni0poh9	684	93	and	and	CC
cord-008530-yni0poh9	684	94	proinflammatory	proinflammatory	JJ
cord-008530-yni0poh9	684	95	cytokines	cytokine	NNS
cord-008530-yni0poh9	684	96	in	in	IN
cord-008530-yni0poh9	684	97	the	the	DT
cord-008530-yni0poh9	684	98	eye	eye	NN
cord-008530-yni0poh9	684	99	:	:	:
cord-008530-yni0poh9	685	1	implications	implication	NNS
cord-008530-yni0poh9	685	2	in	in	IN
cord-008530-yni0poh9	685	3	herpetic	herpetic	JJ
cord-008530-yni0poh9	685	4	stromal	stromal	JJ
cord-008530-yni0poh9	685	5	keratitis	keratitis	NN
cord-008530-yni0poh9	685	6	Glucocorticoids	Glucocorticoids	NNP
cord-008530-yni0poh9	685	7	downregulate	downregulate	VBP
cord-008530-yni0poh9	685	8	gene	gene	NN
cord-008530-yni0poh9	685	9	expression	expression	NN
cord-008530-yni0poh9	685	10	of	of	IN
cord-008530-yni0poh9	685	11	GM	GM	NNP
cord-008530-yni0poh9	685	12	-	-	HYPH
cord-008530-yni0poh9	685	13	CSF	CSF	NNP
cord-008530-yni0poh9	685	14	,	,	,
cord-008530-yni0poh9	685	15	NAP-1	NAP-1	NNP
cord-008530-yni0poh9	685	16	/	/	SYM
cord-008530-yni0poh9	685	17	IL-8	IL-8	NNP
cord-008530-yni0poh9	685	18	,	,	,
cord-008530-yni0poh9	685	19	and	and	CC
cord-008530-yni0poh9	685	20	IL-6	IL-6	NNP
cord-008530-yni0poh9	685	21	,	,	,
cord-008530-yni0poh9	686	1	but	but	CC
cord-008530-yni0poh9	686	2	not	not	RB
cord-008530-yni0poh9	686	3	of	of	IN
cord-008530-yni0poh9	686	4	M	M	NNP
cord-008530-yni0poh9	686	5	-	-	HYPH
cord-008530-yni0poh9	686	6	CSF	CSF	NNP
cord-008530-yni0poh9	686	7	in	in	IN
cord-008530-yni0poh9	686	8	human	human	JJ
cord-008530-yni0poh9	686	9	fibroblasts	fibroblast	NNS
cord-008530-yni0poh9	687	1	Central	central	JJ
cord-008530-yni0poh9	687	2	nervous	nervous	JJ
cord-008530-yni0poh9	687	3	system	system	NN
cord-008530-yni0poh9	687	4	damage	damage	NN
cord-008530-yni0poh9	687	5	produced	produce	VBN
cord-008530-yni0poh9	687	6	by	by	IN
cord-008530-yni0poh9	687	7	expression	expression	NN
cord-008530-yni0poh9	687	8	of	of	IN
cord-008530-yni0poh9	687	9	the	the	DT
cord-008530-yni0poh9	687	10	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	687	11	coat	coat	NN
cord-008530-yni0poh9	687	12	protein	protein	NN
cord-008530-yni0poh9	687	13	gpl20	gpl20	NN
cord-008530-yni0poh9	687	14	in	in	IN
cord-008530-yni0poh9	687	15	transgenic	transgenic	JJ
cord-008530-yni0poh9	687	16	mice	mouse	NNS
cord-008530-yni0poh9	688	1	Immunocytochemical	Immunocytochemical	NNP
cord-008530-yni0poh9	688	2	analysis	analysis	NN
cord-008530-yni0poh9	688	3	of	of	IN
cord-008530-yni0poh9	688	4	the	the	DT
cord-008530-yni0poh9	688	5	cellular	cellular	JJ
cord-008530-yni0poh9	688	6	infiltrate	infiltrate	NN
cord-008530-yni0poh9	688	7	in	in	IN
cord-008530-yni0poh9	688	8	the	the	DT
cord-008530-yni0poh9	688	9	spinal	spinal	JJ
cord-008530-yni0poh9	688	10	cord	cord	NN
cord-008530-yni0poh9	688	11	lesions	lesion	NNS
cord-008530-yni0poh9	688	12	in	in	IN
cord-008530-yni0poh9	688	13	HTLV	HTLV	NNP
cord-008530-yni0poh9	688	14	-	-	HYPH
cord-008530-yni0poh9	688	15	I	I	NNP
cord-008530-yni0poh9	688	16	-	-	HYPH
cord-008530-yni0poh9	688	17	associated	associate	VBN
cord-008530-yni0poh9	688	18	myelopathy	myelopathy	NN
cord-008530-yni0poh9	688	19	Expression	expression	NN
cord-008530-yni0poh9	688	20	of	of	IN
cord-008530-yni0poh9	688	21	adhesion	adhesion	NN
cord-008530-yni0poh9	688	22	molecules	molecule	NNS
cord-008530-yni0poh9	688	23	and	and	CC
cord-008530-yni0poh9	688	24	monocyte	monocyte	NNP
cord-008530-yni0poh9	688	25	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	688	26	protein-1	protein-1	NNP
cord-008530-yni0poh9	688	27	(	(	-LRB-
cord-008530-yni0poh9	688	28	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	688	29	)	)	-RRB-
cord-008530-yni0poh9	688	30	in	in	IN
cord-008530-yni0poh9	688	31	the	the	DT
cord-008530-yni0poh9	688	32	spinal	spinal	JJ
cord-008530-yni0poh9	688	33	cord	cord	NN
cord-008530-yni0poh9	688	34	lesions	lesion	NNS
cord-008530-yni0poh9	688	35	in	in	IN
cord-008530-yni0poh9	688	36	HTLV	HTLV	NNP
cord-008530-yni0poh9	688	37	-	-	HYPH
cord-008530-yni0poh9	688	38	I	I	NNP
cord-008530-yni0poh9	688	39	-	-	HYPH
cord-008530-yni0poh9	688	40	associated	associate	VBN
cord-008530-yni0poh9	688	41	myelopathy	myelopathy	NN
cord-008530-yni0poh9	688	42	Localization	Localization	NNP
cord-008530-yni0poh9	688	43	of	of	IN
cord-008530-yni0poh9	688	44	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	688	45	co	co	NNS
cord-008530-yni0poh9	688	46	-	-	NNS
cord-008530-yni0poh9	688	47	receptors	receptor	NNS
cord-008530-yni0poh9	688	48	CCR5	CCR5	NNP
cord-008530-yni0poh9	688	49	and	and	CC
cord-008530-yni0poh9	688	50	CXCR4	CXCR4	NNS
cord-008530-yni0poh9	688	51	in	in	IN
cord-008530-yni0poh9	688	52	the	the	DT
cord-008530-yni0poh9	688	53	brain	brain	NN
cord-008530-yni0poh9	688	54	of	of	IN
cord-008530-yni0poh9	688	55	children	child	NNS
cord-008530-yni0poh9	688	56	with	with	IN
cord-008530-yni0poh9	688	57	AIDS	AIDS	NNP
cord-008530-yni0poh9	688	58	Expression	Expression	NNP
cord-008530-yni0poh9	688	59	of	of	IN
cord-008530-yni0poh9	688	60	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	688	61	by	by	IN
cord-008530-yni0poh9	688	62	reactive	reactive	JJ
cord-008530-yni0poh9	688	63	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	688	64	in	in	IN
cord-008530-yni0poh9	688	65	demyelinating	demyelinate	VBG
cord-008530-yni0poh9	688	66	multiple	multiple	JJ
cord-008530-yni0poh9	688	67	sclerosis	sclerosis	NN
cord-008530-yni0poh9	688	68	lesions	lesion	NNS
cord-008530-yni0poh9	689	1	Interferon	interferon	NN
cord-008530-yni0poh9	689	2	---	---	:
cord-008530-yni0poh9	689	3	inducible	inducible	JJ
cord-008530-yni0poh9	689	4	genes	gene	NNS
cord-008530-yni0poh9	689	5	in	in	IN
cord-008530-yni0poh9	689	6	primary	primary	JJ
cord-008530-yni0poh9	689	7	glial	glial	JJ
cord-008530-yni0poh9	689	8	cells	cell	NNS
cord-008530-yni0poh9	689	9	of	of	IN
cord-008530-yni0poh9	689	10	the	the	DT
cord-008530-yni0poh9	689	11	central	central	JJ
cord-008530-yni0poh9	689	12	nervous	nervous	JJ
cord-008530-yni0poh9	689	13	system	system	NN
cord-008530-yni0poh9	689	14	:	:	:
cord-008530-yni0poh9	689	15	comparisons	comparison	NNS
cord-008530-yni0poh9	689	16	of	of	IN
cord-008530-yni0poh9	689	17	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	689	18	with	with	IN
cord-008530-yni0poh9	689	19	microglia	microglia	NNS
cord-008530-yni0poh9	689	20	and	and	CC
cord-008530-yni0poh9	689	21	Lewis	Lewis	NNP
cord-008530-yni0poh9	689	22	with	with	IN
cord-008530-yni0poh9	689	23	brown	brown	JJ
cord-008530-yni0poh9	689	24	Norway	Norway	NNP
cord-008530-yni0poh9	689	25	rats	rat	NNS
cord-008530-yni0poh9	689	26	IFN	IFN	NNP
cord-008530-yni0poh9	689	27	and	and	CC
cord-008530-yni0poh9	689	28	virus	virus	NN
cord-008530-yni0poh9	689	29	-	-	HYPH
cord-008530-yni0poh9	689	30	inducible	inducible	JJ
cord-008530-yni0poh9	689	31	expression	expression	NN
cord-008530-yni0poh9	689	32	of	of	IN
cord-008530-yni0poh9	689	33	an	an	DT
cord-008530-yni0poh9	689	34	immediate	immediate	JJ
cord-008530-yni0poh9	689	35	early	early	JJ
cord-008530-yni0poh9	689	36	gene	gene	NN
cord-008530-yni0poh9	689	37	,	,	,
cord-008530-yni0poh9	689	38	crg-2	crg-2	NNP
cord-008530-yni0poh9	689	39	/	/	SYM
cord-008530-yni0poh9	689	40	IP	IP	NNP
cord-008530-yni0poh9	689	41	-	-	HYPH
cord-008530-yni0poh9	689	42	lO	lO	NNP
cord-008530-yni0poh9	689	43	,	,	,
cord-008530-yni0poh9	689	44	and	and	CC
cord-008530-yni0poh9	689	45	a	a	DT
cord-008530-yni0poh9	689	46	delayed	delay	VBN
cord-008530-yni0poh9	689	47	gene	gene	NN
cord-008530-yni0poh9	689	48	,	,	,
cord-008530-yni0poh9	689	49	I	I	NNP
cord-008530-yni0poh9	689	50	-	-	HYPH
cord-008530-yni0poh9	689	51	Ao~	Ao~	NNP
cord-008530-yni0poh9	689	52	in	in	IN
cord-008530-yni0poh9	689	53	astrocytes	astrocyte	NNS
cord-008530-yni0poh9	689	54	and	and	CC
cord-008530-yni0poh9	689	55	microglia	microglia	JJ
cord-008530-yni0poh9	689	56	Molecular	molecular	JJ
cord-008530-yni0poh9	689	57	cloning	clone	VBG
cord-008530-yni0poh9	689	58	,	,	,
cord-008530-yni0poh9	689	59	functional	functional	JJ
cord-008530-yni0poh9	689	60	characterization	characterization	NN
cord-008530-yni0poh9	689	61	and	and	CC
cord-008530-yni0poh9	689	62	mRNA	mRNA	NNP
cord-008530-yni0poh9	689	63	expression	expression	NN
cord-008530-yni0poh9	689	64	analysis	analysis	NN
cord-008530-yni0poh9	689	65	of	of	IN
cord-008530-yni0poh9	689	66	the	the	DT
cord-008530-yni0poh9	689	67	murine	murine	JJ
cord-008530-yni0poh9	689	68	chemokine	chemokine	NN
cord-008530-yni0poh9	689	69	receptor	receptor	NN
cord-008530-yni0poh9	689	70	CCR6	CCR6	NNP
cord-008530-yni0poh9	689	71	and	and	CC
cord-008530-yni0poh9	689	72	its	-PRON-	PRP$
cord-008530-yni0poh9	689	73	specific	specific	JJ
cord-008530-yni0poh9	689	74	ligand	ligand	NN
cord-008530-yni0poh9	689	75	MIP-3a	MIP-3a	NNP
cord-008530-yni0poh9	689	76	Monocyte	Monocyte	NNP
cord-008530-yni0poh9	689	77	chemoattractant	chemoattractant	NN
cord-008530-yni0poh9	689	78	protein-1	protein-1	NNP
cord-008530-yni0poh9	689	79	(	(	-LRB-
cord-008530-yni0poh9	689	80	MCP-1	MCP-1	NNP
cord-008530-yni0poh9	689	81	)	)	-RRB-
cord-008530-yni0poh9	689	82	expression	expression	NN
cord-008530-yni0poh9	689	83	in	in	IN
cord-008530-yni0poh9	689	84	human	human	JJ
cord-008530-yni0poh9	689	85	articular	articular	JJ
cord-008530-yni0poh9	689	86	cartilage	cartilage	NN
cord-008530-yni0poh9	689	87	.	.	.
cord-008530-yni0poh9	690	1	Induction	induction	NN
cord-008530-yni0poh9	690	2	by	by	IN
cord-008530-yni0poh9	690	3	peptide	peptide	JJ
cord-008530-yni0poh9	690	4	regulatory	regulatory	JJ
cord-008530-yni0poh9	690	5	factors	factor	NNS
cord-008530-yni0poh9	690	6	and	and	CC
cord-008530-yni0poh9	690	7	differential	differential	JJ
cord-008530-yni0poh9	690	8	effects	effect	NNS
cord-008530-yni0poh9	690	9	of	of	IN
cord-008530-yni0poh9	690	10	dexamethasone	dexamethasone	NN
cord-008530-yni0poh9	690	11	and	and	CC
cord-008530-yni0poh9	690	12	retinoic	retinoic	JJ
cord-008530-yni0poh9	690	13	acid	acid	NN
cord-008530-yni0poh9	690	14	Pathogenesis	Pathogenesis	NNP
cord-008530-yni0poh9	690	15	of	of	IN
cord-008530-yni0poh9	690	16	demyelination	demyelination	NN
cord-008530-yni0poh9	690	17	induced	induce	VBN
cord-008530-yni0poh9	690	18	by	by	IN
cord-008530-yni0poh9	690	19	a	a	DT
cord-008530-yni0poh9	690	20	mouse	mouse	NN
cord-008530-yni0poh9	690	21	hepatitis	hepatitis	NN
cord-008530-yni0poh9	690	22	virus	virus	NN
cord-008530-yni0poh9	690	23	(	(	-LRB-
cord-008530-yni0poh9	690	24	JHM	JHM	NNP
cord-008530-yni0poh9	690	25	virus	virus	NN
cord-008530-yni0poh9	690	26	)	)	-RRB-
cord-008530-yni0poh9	691	1	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	691	2	Tat	Tat	NNP
cord-008530-yni0poh9	691	3	induces	induce	VBZ
cord-008530-yni0poh9	691	4	monocyte	monocyte	NNP
cord-008530-yni0poh9	691	5	chemoattractant	chemoattractant	NNP
cord-008530-yni0poh9	691	6	protein	protein	NN
cord-008530-yni0poh9	691	7	-	-	HYPH
cord-008530-yni0poh9	691	8	l	l	NN
cord-008530-yni0poh9	691	9	-	-	HYPH
cord-008530-yni0poh9	691	10	mediated	mediate	VBN
cord-008530-yni0poh9	691	11	monocyte	monocyte	NNP
cord-008530-yni0poh9	691	12	transmigration	transmigration	NN
cord-008530-yni0poh9	691	13	across	across	IN
cord-008530-yni0poh9	691	14	a	a	DT
cord-008530-yni0poh9	691	15	model	model	NN
cord-008530-yni0poh9	691	16	of	of	IN
cord-008530-yni0poh9	691	17	the	the	DT
cord-008530-yni0poh9	691	18	human	human	JJ
cord-008530-yni0poh9	691	19	blood	blood	NN
cord-008530-yni0poh9	691	20	-	-	HYPH
cord-008530-yni0poh9	691	21	brain	brain	NN
cord-008530-yni0poh9	691	22	barrier	barrier	NN
cord-008530-yni0poh9	691	23	and	and	CC
cord-008530-yni0poh9	691	24	up	up	RB
cord-008530-yni0poh9	691	25	-	-	HYPH
cord-008530-yni0poh9	691	26	regulates	regulate	VBZ
cord-008530-yni0poh9	691	27	CCR5	ccr5	JJ
cord-008530-yni0poh9	691	28	expression	expression	NN
cord-008530-yni0poh9	691	29	on	on	IN
cord-008530-yni0poh9	691	30	human	human	JJ
cord-008530-yni0poh9	691	31	monocytes	monocyte	NNS
cord-008530-yni0poh9	691	32	Binding	Binding	NNP
cord-008530-yni0poh9	691	33	and	and	CC
cord-008530-yni0poh9	691	34	functional	functional	JJ
cord-008530-yni0poh9	691	35	properties	property	NNS
cord-008530-yni0poh9	691	36	of	of	IN
cord-008530-yni0poh9	691	37	recombinant	recombinant	JJ
cord-008530-yni0poh9	691	38	and	and	CC
cord-008530-yni0poh9	691	39	endogenous	endogenous	JJ
cord-008530-yni0poh9	691	40	CXCR3	cxcr3	NN
cord-008530-yni0poh9	691	41	chemokine	chemokine	NN
cord-008530-yni0poh9	691	42	receptors	receptor	NNS
cord-008530-yni0poh9	691	43	Chemokine	Chemokine	NNP
cord-008530-yni0poh9	691	44	receptor	receptor	NN
cord-008530-yni0poh9	691	45	expression	expression	NN
cord-008530-yni0poh9	691	46	on	on	IN
cord-008530-yni0poh9	691	47	resident	resident	JJ
cord-008530-yni0poh9	691	48	and	and	CC
cord-008530-yni0poh9	691	49	inflammatory	inflammatory	JJ
cord-008530-yni0poh9	691	50	cells	cell	NNS
cord-008530-yni0poh9	691	51	in	in	IN
cord-008530-yni0poh9	691	52	the	the	DT
cord-008530-yni0poh9	691	53	brain	brain	NN
cord-008530-yni0poh9	691	54	of	of	IN
cord-008530-yni0poh9	691	55	macaques	macaque	NNS
cord-008530-yni0poh9	691	56	with	with	IN
cord-008530-yni0poh9	691	57	simian	simian	JJ
cord-008530-yni0poh9	691	58	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	691	59	virus	virus	NN
cord-008530-yni0poh9	691	60	encephalitis	encephalitis	RB
cord-008530-yni0poh9	691	61	Rat	Rat	NNP
cord-008530-yni0poh9	691	62	LCRI	LCRI	NNP
cord-008530-yni0poh9	691	63	:	:	:
cord-008530-yni0poh9	691	64	cloning	clone	VBG
cord-008530-yni0poh9	691	65	and	and	CC
cord-008530-yni0poh9	691	66	cellular	cellular	JJ
cord-008530-yni0poh9	691	67	distribution	distribution	NN
cord-008530-yni0poh9	691	68	of	of	IN
cord-008530-yni0poh9	691	69	a	a	DT
cord-008530-yni0poh9	691	70	putative	putative	JJ
cord-008530-yni0poh9	691	71	chemokine	chemokine	NN
cord-008530-yni0poh9	691	72	receptor	receptor	NN
cord-008530-yni0poh9	691	73	in	in	IN
cord-008530-yni0poh9	691	74	brain	brain	NN
cord-008530-yni0poh9	691	75	Neuroaxonal	neuroaxonal	JJ
cord-008530-yni0poh9	691	76	dystrophy	dystrophy	NN
cord-008530-yni0poh9	691	77	in	in	IN
cord-008530-yni0poh9	691	78	HTLV	HTLV	NNP
cord-008530-yni0poh9	691	79	-	-	HYPH
cord-008530-yni0poh9	691	80	l	l	NN
cord-008530-yni0poh9	691	81	-	-	HYPH
cord-008530-yni0poh9	691	82	associated	associate	VBN
cord-008530-yni0poh9	691	83	myelopathy	myelopathy	NN
cord-008530-yni0poh9	691	84	/	/	SYM
cord-008530-yni0poh9	691	85	tropical	tropical	JJ
cord-008530-yni0poh9	691	86	spastic	spastic	JJ
cord-008530-yni0poh9	691	87	paraparesis	paraparesis	NN
cord-008530-yni0poh9	691	88	:	:	:
cord-008530-yni0poh9	691	89	neuropathologic	neuropathologic	NNP
cord-008530-yni0poh9	691	90	and	and	CC
cord-008530-yni0poh9	691	91	neuroimmunologic	neuroimmunologic	NNP
cord-008530-yni0poh9	691	92	correlations	correlation	NNS
cord-008530-yni0poh9	691	93	CCR5	CCR5	NNP
cord-008530-yni0poh9	691	94	levels	level	NNS
cord-008530-yni0poh9	691	95	and	and	CC
cord-008530-yni0poh9	691	96	expression	expression	NN
cord-008530-yni0poh9	691	97	pattern	pattern	NN
cord-008530-yni0poh9	691	98	correlate	correlate	VBP
cord-008530-yni0poh9	691	99	with	with	IN
cord-008530-yni0poh9	691	100	infectability	infectability	NN
cord-008530-yni0poh9	691	101	by	by	IN
cord-008530-yni0poh9	691	102	macrophage	macrophage	NN
cord-008530-yni0poh9	691	103	-	-	HYPH
cord-008530-yni0poh9	691	104	tropic	tropic	NN
cord-008530-yni0poh9	691	105	HIV-1	HIV-1	NNP
cord-008530-yni0poh9	691	106	,	,	,
cord-008530-yni0poh9	691	107	in	in	IN
cord-008530-yni0poh9	691	108	vitro	vitro	FW
cord-008530-yni0poh9	691	109	Immunohistochemical	Immunohistochemical	NNP
cord-008530-yni0poh9	691	110	study	study	NN
cord-008530-yni0poh9	691	111	of	of	IN
cord-008530-yni0poh9	691	112	the	the	DT
cord-008530-yni0poh9	691	113	beta	beta	JJ
cord-008530-yni0poh9	691	114	-	-	HYPH
cord-008530-yni0poh9	691	115	chemokine	chemokine	NN
cord-008530-yni0poh9	691	116	receptors	receptor	NNS
cord-008530-yni0poh9	691	117	CCR3	CCR3	NNP
cord-008530-yni0poh9	691	118	and	and	CC
cord-008530-yni0poh9	691	119	CCR5	CCR5	NNP
cord-008530-yni0poh9	691	120	and	and	CC
cord-008530-yni0poh9	691	121	their	-PRON-	PRP$
cord-008530-yni0poh9	691	122	ligands	ligand	NNS
cord-008530-yni0poh9	691	123	in	in	IN
cord-008530-yni0poh9	691	124	normal	normal	JJ
cord-008530-yni0poh9	691	125	and	and	CC
cord-008530-yni0poh9	691	126	Alzheimer	Alzheimer	NNP
cord-008530-yni0poh9	691	127	's	's	POS
cord-008530-yni0poh9	691	128	disease	disease	NN
cord-008530-yni0poh9	691	129	brains	brain	NNS
cord-008530-yni0poh9	691	130	Molecular	molecular	JJ
cord-008530-yni0poh9	691	131	cloning	clone	VBG
cord-008530-yni0poh9	691	132	of	of	IN
cord-008530-yni0poh9	691	133	a	a	DT
cord-008530-yni0poh9	691	134	novel	novel	JJ
cord-008530-yni0poh9	691	135	human	human	NN
cord-008530-yni0poh9	691	136	CC	cc	NN
cord-008530-yni0poh9	691	137	chemokine	chemokine	NN
cord-008530-yni0poh9	691	138	EBIl	EBIl	NNS
cord-008530-yni0poh9	691	139	-	-	HYPH
cord-008530-yni0poh9	691	140	ligand	ligand	NN
cord-008530-yni0poh9	691	141	chemokine	chemokine	NN
cord-008530-yni0poh9	691	142	that	that	WDT
cord-008530-yni0poh9	691	143	is	be	VBZ
cord-008530-yni0poh9	691	144	a	a	DT
cord-008530-yni0poh9	691	145	specific	specific	JJ
cord-008530-yni0poh9	691	146	functional	functional	JJ
cord-008530-yni0poh9	691	147	ligand	ligand	NN
cord-008530-yni0poh9	691	148	for	for	IN
cord-008530-yni0poh9	691	149	EBI1	EBI1	NNP
cord-008530-yni0poh9	691	150	,	,	,
cord-008530-yni0poh9	691	151	CCR7	CCR7	NNP
cord-008530-yni0poh9	691	152	Identification	Identification	NNP
cord-008530-yni0poh9	691	153	of	of	IN
cord-008530-yni0poh9	691	154	single	single	JJ
cord-008530-yni0poh9	691	155	C	c	NN
cord-008530-yni0poh9	691	156	motif	motif	NN
cord-008530-yni0poh9	691	157	-	-	HYPH
cord-008530-yni0poh9	691	158	lflymphotactin	lflymphotactin	NN
cord-008530-yni0poh9	691	159	receptor	receptor	NN
cord-008530-yni0poh9	691	160	XCR1	XCR1	NNP
cord-008530-yni0poh9	691	161	Molecular	Molecular	NNP
cord-008530-yni0poh9	691	162	cloning	cloning	NN
cord-008530-yni0poh9	691	163	of	of	IN
cord-008530-yni0poh9	691	164	a	a	DT
cord-008530-yni0poh9	691	165	novel	novel	NN
cord-008530-yni0poh9	692	1	C-)~	C-)~	NNP
cord-008530-yni0poh9	692	2	or	or	CC
cord-008530-yni0poh9	692	3	~/-type	~/-type	CD
cord-008530-yni0poh9	692	4	chemokine	chemokine	NN
cord-008530-yni0poh9	692	5	,	,	.
cord-008530-yni0poh9	693	1	SCM-1	SCM-1	NNP
cord-008530-yni0poh9	693	2	Cutting	cut	VBG
cord-008530-yni0poh9	693	3	edge	edge	NN
cord-008530-yni0poh9	693	4	:	:	:
cord-008530-yni0poh9	693	5	identification	identification	NN
cord-008530-yni0poh9	693	6	of	of	IN
cord-008530-yni0poh9	693	7	the	the	DT
cord-008530-yni0poh9	693	8	orphan	orphan	NN
cord-008530-yni0poh9	693	9	chemokine	chemokine	NN
cord-008530-yni0poh9	693	10	receptor	receptor	NN
cord-008530-yni0poh9	693	11	GPR-9	GPR-9	NNP
cord-008530-yni0poh9	693	12	-	-	HYPH
cord-008530-yni0poh9	693	13	6	6	CD
cord-008530-yni0poh9	693	14	as	as	IN
cord-008530-yni0poh9	693	15	CCR9	CCR9	NNP
cord-008530-yni0poh9	693	16	,	,	,
cord-008530-yni0poh9	693	17	the	the	DT
cord-008530-yni0poh9	693	18	receptor	receptor	NN
cord-008530-yni0poh9	693	19	for	for	IN
cord-008530-yni0poh9	693	20	the	the	DT
cord-008530-yni0poh9	693	21	chemokine	chemokine	NN
cord-008530-yni0poh9	694	1	TECK	TECK	NNP
cord-008530-yni0poh9	694	2	Lymphotropic	Lymphotropic	NNP
cord-008530-yni0poh9	694	3	virions	virion	NNS
cord-008530-yni0poh9	694	4	affect	affect	VBP
cord-008530-yni0poh9	694	5	chemokine	chemokine	NN
cord-008530-yni0poh9	694	6	receptor	receptor	NN
cord-008530-yni0poh9	694	7	-	-	HYPH
cord-008530-yni0poh9	694	8	mediated	mediate	VBN
cord-008530-yni0poh9	694	9	neural	neural	JJ
cord-008530-yni0poh9	694	10	signaling	signaling	NN
cord-008530-yni0poh9	694	11	and	and	CC
cord-008530-yni0poh9	694	12	apoptosis	apoptosis	NN
cord-008530-yni0poh9	694	13	:	:	:
cord-008530-yni0poh9	694	14	implications	implication	NNS
cord-008530-yni0poh9	694	15	for	for	IN
cord-008530-yni0poh9	694	16	human	human	JJ
cord-008530-yni0poh9	694	17	immunodeficiency	immunodeficiency	NN
cord-008530-yni0poh9	694	18	virus	virus	NN
cord-008530-yni0poh9	694	19	type	type	NN
cord-008530-yni0poh9	694	20	1-associated	1-associated	CD
cord-008530-yni0poh9	694	21	dementia	dementia	NN
cord-008530-yni0poh9	695	1	Intracellular	Intracellular	NNP
cord-008530-yni0poh9	695	2	CXCR4	cxcr4	IN
cord-008530-yni0poh9	695	3	signaling	signal	VBG
cord-008530-yni0poh9	695	4	,	,	,
cord-008530-yni0poh9	695	5	neuronal	neuronal	JJ
cord-008530-yni0poh9	695	6	apoptosis	apoptosis	NN
cord-008530-yni0poh9	695	7	and	and	CC
cord-008530-yni0poh9	695	8	neuropathogenic	neuropathogenic	JJ
cord-008530-yni0poh9	695	9	mechanisms	mechanism	NNS
cord-008530-yni0poh9	695	10	of	of	IN
cord-008530-yni0poh9	695	11	HIV	HIV	NNP
cord-008530-yni0poh9	695	12	-	-	HYPH
cord-008530-yni0poh9	695	13	l	l	NN
cord-008530-yni0poh9	695	14	-	-	HYPH
cord-008530-yni0poh9	695	15	associated	associate	VBN
cord-008530-yni0poh9	695	16	dementia	dementia	NN
cord-008530-yni0poh9	696	1	The	the	DT
cord-008530-yni0poh9	696	2	chemokine	chemokine	NN
cord-008530-yni0poh9	696	3	receptor	receptor	NN
cord-008530-yni0poh9	696	4	CCR8	CCR8	NNP
cord-008530-yni0poh9	696	5	is	be	VBZ
cord-008530-yni0poh9	696	6	preferentially	preferentially	RB
cord-008530-yni0poh9	696	7	expressed	express	VBN
cord-008530-yni0poh9	696	8	in	in	IN
cord-008530-yni0poh9	696	9	Th2	Th2	NNP
cord-008530-yni0poh9	696	10	but	but	CC
cord-008530-yni0poh9	696	11	not	not	RB
cord-008530-yni0poh9	696	12	Thl	Thl	NNP
cord-008530-yni0poh9	696	13	cells	cell	NNS
cord-008530-yni0poh9	697	1	Recent	recent	JJ
cord-008530-yni0poh9	697	2	advances	advance	NNS
cord-008530-yni0poh9	697	3	in	in	IN
cord-008530-yni0poh9	697	4	chemokines	chemokine	NNS
cord-008530-yni0poh9	697	5	and	and	CC
cord-008530-yni0poh9	697	6	chemokine	chemokine	NN
cord-008530-yni0poh9	697	7	receptors	receptor	NNS
cord-008530-yni0poh9	697	8	Function	function	NN
cord-008530-yni0poh9	697	9	of	of	IN
cord-008530-yni0poh9	697	10	the	the	DT
cord-008530-yni0poh9	697	11	chemokine	chemokine	NN
cord-008530-yni0poh9	697	12	receptor	receptor	NN
cord-008530-yni0poh9	697	13	CXCR4	CXCR4	NNP
cord-008530-yni0poh9	697	14	in	in	IN
cord-008530-yni0poh9	697	15	haematopoiesis	haematopoiesis	NN
cord-008530-yni0poh9	697	16	and	and	CC
cord-008530-yni0poh9	697	17	in	in	IN
cord-008530-yni0poh9	697	18	cerebellar	cerebellar	JJ
cord-008530-yni0poh9	697	19	development	development	NN