id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-354974-bh2expef	Peterson, Ingrid	Respiratory Virus–Associated Severe Acute Respiratory Illness and Viral Clustering in Malawian Children in a Setting With a High Prevalence of HIV Infection, Malaria, and Malnutrition	2016-09-13		.txt	text/plain	3863	192	45	BACKGROUND: We used data from 4 years of pediatric severe acute respiratory illness (SARI) sentinel surveillance in Blantyre, Malawi, to identify factors associated with clinical severity and coviral clustering. A total of 605 SARI cases (26.8%) had warning signs, which were positively associated with HIV infection (adjusted risk ratio [aRR], 2.4; 95% confidence interval [CI], 1.4–3.9), respiratory syncytial virus infection (aRR, 1.9; 95% CI, 1.3–3.0) and rainy season (aRR, 2.4; 95% CI, 1.6–3.8). In the context of a low-income population with multiple drivers of immune compromise (eg, human immunodeficiency virus [HIV] infection, malnutrition, and malaria) [11] , we conducted active surveillance at a large urban teaching hospital in Malawi to estimate the incidence of childhood SARI and explore the association of SARI clinical severity with HIV infection and clustering of respiratory viral coinfection. After adjustment for age, sex, and HIV status, rainy season recruitment was significantly associated with SARI with warning signs in influenza virus-positive patients with SARI (aRR, 3.42; 95% CI, 1.37-8.53; analysis not shown).	./cache/cord-354974-bh2expef.txt	./txt/cord-354974-bh2expef.txt