id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-354029-mp5r82g4	Earp, L. J.	The Many Mechanisms of Viral Membrane Fusion Proteins	2005		.txt	text/plain	12130	702	50	Despite their differences, common principles for how fusion proteins function are emerging: In response to an activating trigger, the metastable fusion protein converts to an extended, in some cases rodlike structure, which inserts into the target membrane via its fusion peptide. Although several viral fusion proteins, such as influenza hemagglutinin (HA) and the human immunodeficiency virus (HIV) envelope glycoprotein (Env), have emerged as paradigms, it is important to realize that there are many distinguishing features among viral fusion proteins (Table 1 ). We now review a lipid rearrangement model and focus on the roles of different regions of viral fusion proteins in choreographing the structural changes that the membranes undergo throughout the fusion cascade (Fig. 3) . Cellular membrane-binding ability of the C-terminal cytoplasmic domain of human immunodeficiency virus type 1 envelope transmembrane protein gp41 Role of the N-terminal peptides of viral envelope proteins in membrane fusion	./cache/cord-354029-mp5r82g4.txt	./txt/cord-354029-mp5r82g4.txt