id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347710-ff64y6ef	Wan, Qianya	Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development	2020-07-13		.txt	text/plain	36567	2487	46	hnRNPs involve in a large number of cellular processes, including chromatin remodelling, transcription regulation, RNP assembly and stabilization, RNA export, virus replication, histone-like nucleoid structuring, and even intracellular immunity. 6, 13 It is well known that Hsp90 not only interacts and contributes to RNA polymerase assembly and nuclear import of some (−) ssRNA viruses (e.g., PB2 of influenza virus), but plays crucial roles in the folding process of viral capsid proteins and virion assemblies as well. 17, 18 As a critical component of cellular protein surveillance, the ATP-dependent molecular chaperone protects cells from damage caused by stress and takes part in a number of folding processes, including folding of newly synthesized polypeptides, recognition and refolding of misfolded or aggregated proteins, solubilization or degradation of proteins, transporting proteins, assembly or disassembly of oligomeric protein complexes, and the regulation of certain natively folded proteins.	./cache/cord-347710-ff64y6ef.txt	./txt/cord-347710-ff64y6ef.txt