id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-333622-0ddutmdd	Dyer, Wayne B	Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection	2008-12-11		.txt	text/plain	5615	243	44	title: Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection Early studies on this cohort of TAHIV patients led to the identification of the Sydney Blood Bank Cohort (SBBC) of long-term survivors [8] , and that an attenuated nef-deleted strain of HIV-1, transmitted from a single donor resulted in slow to non-progression in these individuals [9] . In addition to the well described host genetic factors which may prolong non-progression [7] , recent studies have suggested an influence from innate immune mechanisms, including polymorphisms that decrease TLR function thereby reducing immune activation upon exposure to infections diseases [18] , or the FcγRIIA polymorphism (R/R) which is strongly associated with progressive HIV disease as a result of impaired elimination of HIV immune complexes [19] .	./cache/cord-333622-0ddutmdd.txt	./txt/cord-333622-0ddutmdd.txt