id author title date pages extension mime words sentences flesch summary cache txt cord-333405-ji58jbct Morens, David M. The challenge of emerging and re-emerging infectious diseases 2004-07-08 .txt text/plain 6421 315 41 Of the 'newly emerging' and 're-emerging/resurging' diseases that have followed the appearance of AIDS (Fig. 1) , some have been minor curiosities, such as the 2003 cases of monkeypox imported into the United States 4 , whereas others, such as severe acute respiratory syndrome (SARS), which emerged in the same year 5 , have had a worldwide impact. The impact of both new and re-emerging infectious diseases on human populations is affected by the rate and degree to which they spread across geographical areas, depending on the movement of human hosts or of the vectors or reservoirs of infections. Immune deficiency associated with AIDS, and with chemotherapy for cancer, immune-mediated diseases and transplantation, has contributed to an enormous global increase in the numbers of immunosuppressed people over the past few decades (probably more than 1% of the world's population), setting the stage for the re-emergence of many opportunistic infections. ./cache/cord-333405-ji58jbct.txt ./txt/cord-333405-ji58jbct.txt