id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-331289-02411gfv	Di Minno, Giovanni	Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders()	2015-07-20		.txt	text/plain	8171	395	43	In general, clinicians assess the level of risk associated with the use of blood/ plasma-derived products by evaluating factors such as patient characteristics (e.g. age, immune status, geographical location, lifestyle) and the nature of the pathogen (e.g. physical characteristics, level of virulence, chronicity of infection, prevalence). Current donor selection and screening practices have improved our ability to detect or reduce the presence of pathogens in blood/plasma-derived products; for example, the residual risk of transfusion-transmitted infection (TTI) with HIV/HBV/HCV has fallen to near or less than 1 per million transfused units [14, 15] . Since TTV is often detected in healthy individuals and is not associated with any particular disease, routine screening for this virus is not considered to be necessary; even a test with excellent sensitivity/specificity would not contribute to increase the level of safety of blood/plasma-derived products with regard to TTV.	./cache/cord-331289-02411gfv.txt	./txt/cord-331289-02411gfv.txt