id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-330698-9t24jo8s	Wurdinger, Thomas	Extracellular Vesicles and Their Convergence with Viral Pathways	2012-07-25		.txt	text/plain	7445	365	39	Finally, endogenous retrovirus and retrotransposon elements deposited in our genomes millions of years ago can be released from cells within microvesicles, suggestive of a viral origin of the microvesicle system or perhaps of an evolutionary conserved system of virus-vesicle codependence. Microvesicles released by infected cells contain specific components of the cell and the virus, many of which facilitate the ability of virions to persist in a hostile antiviral immune environment [44, 55, 56, 58] . During HSV-1 infection the release of microvesicles, formerly known as L-particles containing viral tegument proteins and glycoproteins, can prime surrounding cells for productive infection and reduce immune rejection [48] [49] [50] . In the case of the human CMV, microvesicles released by infected cells present the C-type lectin family molecule expressed on dendritic cells-used in capture and internalization of pathogens-in complex with the CMV glycoprotein B. Also, the convergence of these pathways may explain the observations of virus-like particles, which can be exosomes or shed microvesicles containing viral proteins or nucleic acids.	./cache/cord-330698-9t24jo8s.txt	./txt/cord-330698-9t24jo8s.txt