id author title date pages extension mime words sentences flesch summary cache txt cord-321773-5fw9abzl Cheng, Wenyu DDX5 RNA Helicases: Emerging Roles in Viral Infection 2018-04-09 .txt text/plain 6739 370 48 Given the crucial roles of DDX5 in RNA biology, several RNA viruses were found to interact with the protein to promote viral replication (Table 1) , including severe acute respiratory syndrome (SARS) coronavirus (CoV) [16] , human immunodeficiency virus 1 (HIV-1) [17] , hepatitis C virus (HCV) [18] , Japanese encephalitis virus (JEV) [19] , porcine reproductive and respiratory syndrome virus (PRRSV) [20] , and influenza virus [21] . There are several studies that focus on specific inhibitors or drugs of the host DEAD-box helicase to inhibit virus replication or treat cancers [65] [66] [67] , but it remains to be determined whether small molecular inhibitors of the interaction between DDX5 and Rev can be found. The DEAD-box RNA helicase DDX5 acts as a positive regulator of Japanese encephalitis virus replication by binding to viral 3 UTR The DEAD-box RNA helicase 5 positively regulates the replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp9 in vitro ./cache/cord-321773-5fw9abzl.txt ./txt/cord-321773-5fw9abzl.txt