id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320156-xs936r6u	Nunes, Marta C.	Polyomaviruses-associated respiratory infections in HIV-infected and HIV-uninfected children	2014-10-28		.txt	text/plain	3682	186	44	OBJECTIVES: To determine the prevalence and clinical manifestations of WUPyV and KIPyV-associated lower respiratory tract infections (LRTIs) hospitalization in HIV-infected and -uninfected children; and probe the role of pneumococcal co-infection. Co-infections with other respiratory-viruses were detected in 65.5% of WUPyV-positive LRTIs and in 75.0% of KIPyV-positive LRTIs. Among HIV-uninfected children, there was a lower incidence of hospitalization for clinical pneumonia episodes in which KIPyV (80%; 95% CI: 41, 93) and WUPyV (49%; 95% CI: 9, 71) were identified among PCV9-recipients compared to placebo-recipients. The aim of this study was to determine the burden and clinical features of WUPyV and KIPyV infections in HIV-infected and HIV-uninfected children hospitalized for LRTIs. Furthermore, as an exploratory analysis we used the design of a RCT of a 9-valent PCV (PCV9) to probe whether pneumococcal co-infection may contribute to hospitalization for PyV-associated pneumonia.	./cache/cord-320156-xs936r6u.txt	./txt/cord-320156-xs936r6u.txt