id author title date pages extension mime words sentences flesch summary cache txt cord-317213-vhprfb1o Tram, Dai Thien Nhan Advances in nanomaterials and their applications in point of care (POC) devices for the diagnosis of infectious diseases 2016-09-26 .txt text/plain 11575 794 48 This review presents an overview on how the POC-associated nanotechnology, currently applied for the identification of nucleic acids, proteins and antibodies, might be further exploited for the detection of infectious pathogens: although still premature, future integrations of nanoparticles with biological markers that target specific microorganisms will enable timely therapeutic intervention against life-threatening infectious diseases. • no tagging is required • about two orders of magnitude more sensitive than some common colorimetric techniques • selectivity down to the level of single-base mismatch • quantitative signal intensity varied with the length of target RNA sequence (Nam et al., 2004) Analyte: nucleotide sequence indicative of anthrax lethal factor Sample size: 30 μl Assay time: 3-4 h Detection range: 500 zM-5 fM Performance: ./cache/cord-317213-vhprfb1o.txt ./txt/cord-317213-vhprfb1o.txt