id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269222-g2ibmo75	Valenti, Piera	Role of Lactobacilli and Lactoferrin in the Mucosal Cervicovaginal Defense	2018-03-01		.txt	text/plain	9642	449	28	Lactoferrin is strongly increased in lower genital tract mucosal fluid of women affected by Neisseria gonorrheae, Chlamydia trachomatis, and Trichomonas vaginalis infections promoting both innate and adaptive immune responses. Lactoferrin is strongly increased in lower genital tract mucosal fluid of women affected by Neisseria gonorrheae, Chlamydia trachomatis, and Trichomonas vaginalis infections promoting both innate and adaptive immune responses. Lactobacilli exert their protective effects by several mechanisms: (i) microbial competition for the nutrients and for adherence to the vaginal epithelium; (ii) reduction of the vaginal pH by the production of organic acids, especially lactic acid, through the degradation of glycogen released by vaginal cells thus exerting selective antimicrobial activity against non-resident microbiota; (iii) production of antimicrobial substances, such as bacteriocins and hydrogen peroxide (H2O2) able to suppress the growth of several microorganisms; and (iv) modulation of the local immune system (16) .	./cache/cord-269222-g2ibmo75.txt	./txt/cord-269222-g2ibmo75.txt