id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-034714-6e37yylk	Alleg, Manel	Progressive multifocal leukoencephalopathy: MRI findings in HIV-infected patients are closer to rituximab- than natalizumab-associated PML	2020-11-06		.txt	text/plain	3746	170	37	title: Progressive multifocal leukoencephalopathy: MRI findings in HIV-infected patients are closer to rituximabthan natalizumab-associated PML OBJECTIVES: To compare brain MRI findings in progressive multifocal leukoencephalopathy (PML) associated to rituximab and natalizumab treatments and HIV infection. Inclusion criteria were (1) a "definite" PML diagnosis according to the American Academy of Neurology criteria [19] including clinical and imaging-compatible features and detection of JCV DNA in the cerebrospinal fluid or in brain tissue by polymerase chain reaction (PCR) or immunohistochemistry; (2) HIV-infected patients or patients treated with immunomodulatory or immunosuppressive drugs such as natalizumab or rituximab, possibly in association with other drugs and whatever the initial illness; and (3) consent was provided for in the hospital's charter. This study aims to describe the MRI characteristics of PML associated with rituximab and natalizumab and in HIV infection while comparing imaging findings with the level of immunosuppression.	./cache/cord-034714-6e37yylk.txt	./txt/cord-034714-6e37yylk.txt