id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010001-u0d5jkp1	KOTWAL, GIRISH J.	Anti‐HIV, Anti‐Poxvirus, and Anti‐SARS Activity of a Nontoxic, Acidic Plant Extract from the Trifollium Species Secomet‐V/anti‐Vac Suggests That It Contains a Novel Broad‐Spectrum Antiviral	2006-01-22		.txt	text/plain	2608	123	51	With a well-established infrastructure and the methodology to cultivate and to titer viruses accurately 6 to evaluate antiviral effects, it was possible to show that indeed a small volume of the plant extract termed Secomet-V was able to inactivate approximately 1 million virus particles of the attenuated recombinant vaccinia virus vGK5 7 in 1 minute consistently and reproducibly. Secomet-V, an extract of an African plant also found elsewhere in Asia, has been found to have potent antiviral activity against a poxvirus (vaccinia virus), rendering about 1 million particles noninfectious in 1 min with a 50th of a milliliter in in vitro assays (FIG. HIV-infected cells treated with plant extract showed no significant effect on the viral levels (TABLE 1) . There was no difference in the effectiveness of the plant extract in rendering vaccinia virus noninfectious whether it was autoclaved or not, suggesting that the bioactive agent is most likely but not necessarily a heat-stable compound and not a small peptide.	./cache/cord-010001-u0d5jkp1.txt	./txt/cord-010001-u0d5jkp1.txt