id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-033331-giku34r9	Manrique-Saide, Pablo	The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico	2020-10-08		.txt	text/plain	9912	487	45	METHODS/DESIGN: We are pursuing a two-arm, parallel, unblinded, cluster randomized controlled trial to quantify the overall efficacy of TIRS in reducing the burden of laboratory-confirmed ABV clinical disease (primary endpoint). Fitting such entomological information to an agent-based model of Yucatan State, Mexico, showed that high levels of TIRS coverage (75% of houses treated once per year) applied preemptively before the typical dengue season (before July) could reduce DENV infections by 89.7% in year 1 and 78.2% cumulatively over the first 5 years of an annual program [32] . Additionally, our project will access the online ABV database managed by Mexico's National Center of Preventive Programs and Diseases Control (CENAPRECE) [51] to identify all reported symptomatic cases (including all ages, not only children) residing within study clusters in real time, and to map routine vector control actions performed by SSY.	./cache/cord-033331-giku34r9.txt	./txt/cord-033331-giku34r9.txt