id	sid	tid	token	lemma	pos
cord-026340-2nf97zvc	1	1	key	key	JJ
cord-026340-2nf97zvc	1	2	:	:	:
cord-026340-2nf97zvc	1	3	cord-026340	cord-026340	NN
cord-026340-2nf97zvc	1	4	-	-	HYPH
cord-026340-2nf97zvc	1	5	2nf97zvc	2nf97zvc	CD
cord-026340-2nf97zvc	1	6	authors	author	NNS
cord-026340-2nf97zvc	1	7	:	:	:
cord-026340-2nf97zvc	1	8	Singh	Singh	NNP
cord-026340-2nf97zvc	1	9	,	,	,
cord-026340-2nf97zvc	1	10	Ranjana	Ranjana	NNP
cord-026340-2nf97zvc	1	11	;	;	:
cord-026340-2nf97zvc	1	12	Vijayan	Vijayan	NNP
cord-026340-2nf97zvc	1	13	,	,	,
cord-026340-2nf97zvc	1	14	Viji	Viji	NNP
cord-026340-2nf97zvc	2	1	title	title	NN
cord-026340-2nf97zvc	2	2	:	:	:
cord-026340-2nf97zvc	2	3	Chloroquine	chloroquine	NN
cord-026340-2nf97zvc	2	4	:	:	:
cord-026340-2nf97zvc	2	5	A	a	DT
cord-026340-2nf97zvc	2	6	Potential	Potential	NNP
cord-026340-2nf97zvc	2	7	Drug	drug	NN
cord-026340-2nf97zvc	2	8	in	in	IN
cord-026340-2nf97zvc	2	9	the	the	DT
cord-026340-2nf97zvc	2	10	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	2	11	Scenario	Scenario	NNP
cord-026340-2nf97zvc	2	12	date	date	NN
cord-026340-2nf97zvc	2	13	:	:	:
cord-026340-2nf97zvc	2	14	2020	2020	CD
cord-026340-2nf97zvc	2	15	-	-	HYPH
cord-026340-2nf97zvc	2	16	06	06	CD
cord-026340-2nf97zvc	2	17	-	-	HYPH
cord-026340-2nf97zvc	2	18	07	07	CD
cord-026340-2nf97zvc	2	19	journal	journal	NN
cord-026340-2nf97zvc	2	20	:	:	:
cord-026340-2nf97zvc	3	1	Trans	Trans	NNP
cord-026340-2nf97zvc	3	2	Indian	Indian	NNP
cord-026340-2nf97zvc	3	3	Natl	Natl	NNP
cord-026340-2nf97zvc	4	1	DOI	DOI	NNP
cord-026340-2nf97zvc	4	2	:	:	:
cord-026340-2nf97zvc	4	3	10.1007	10.1007	CD
cord-026340-2nf97zvc	4	4	/	/	SYM
cord-026340-2nf97zvc	4	5	s41403	s41403	NNP
cord-026340-2nf97zvc	4	6	-	-	HYPH
cord-026340-2nf97zvc	4	7	020	020	CD
cord-026340-2nf97zvc	4	8	-	-	HYPH
cord-026340-2nf97zvc	4	9	00114-w	00114-w	CD
cord-026340-2nf97zvc	4	10	sha	sha	NNP
cord-026340-2nf97zvc	4	11	:	:	:
cord-026340-2nf97zvc	5	1	198713320dd98ad521ef6558725f922a4d9b8a87	198713320dd98ad521ef6558725f922a4d9b8a87	CD
cord-026340-2nf97zvc	5	2	doc_id	doc_id	CD
cord-026340-2nf97zvc	5	3	:	:	:
cord-026340-2nf97zvc	6	1	26340	26340	CD
cord-026340-2nf97zvc	6	2	cord_uid	cord_uid	NN
cord-026340-2nf97zvc	6	3	:	:	:
cord-026340-2nf97zvc	7	1	2nf97zvc	2nf97zvc	CD
cord-026340-2nf97zvc	7	2	Today	today	NN
cord-026340-2nf97zvc	7	3	,	,	,
cord-026340-2nf97zvc	7	4	the	the	DT
cord-026340-2nf97zvc	7	5	whole	whole	JJ
cord-026340-2nf97zvc	7	6	world	world	NN
cord-026340-2nf97zvc	7	7	is	be	VBZ
cord-026340-2nf97zvc	7	8	fighting	fight	VBG
cord-026340-2nf97zvc	7	9	a	a	DT
cord-026340-2nf97zvc	7	10	public	public	JJ
cord-026340-2nf97zvc	7	11	health	health	NN
cord-026340-2nf97zvc	7	12	emergency	emergency	NN
cord-026340-2nf97zvc	7	13	called	call	VBN
cord-026340-2nf97zvc	7	14	‘	'	``
cord-026340-2nf97zvc	7	15	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	7	16	’	'	''
cord-026340-2nf97zvc	7	17	caused	cause	VBN
cord-026340-2nf97zvc	7	18	by	by	IN
cord-026340-2nf97zvc	7	19	a	a	DT
cord-026340-2nf97zvc	7	20	new	new	JJ
cord-026340-2nf97zvc	7	21	infectious	infectious	JJ
cord-026340-2nf97zvc	7	22	virus	virus	NN
cord-026340-2nf97zvc	7	23	called	call	VBN
cord-026340-2nf97zvc	7	24	SARS	SARS	NNP
cord-026340-2nf97zvc	7	25	-	-	HYPH
cord-026340-2nf97zvc	7	26	CoV2	CoV2	NNP
cord-026340-2nf97zvc	7	27	.	.	.
cord-026340-2nf97zvc	8	1	Any	any	DT
cord-026340-2nf97zvc	8	2	person	person	NN
cord-026340-2nf97zvc	8	3	can	can	MD
cord-026340-2nf97zvc	8	4	catch	catch	VB
cord-026340-2nf97zvc	8	5	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	8	6	from	from	IN
cord-026340-2nf97zvc	8	7	an	an	DT
cord-026340-2nf97zvc	8	8	infected	infected	JJ
cord-026340-2nf97zvc	8	9	person	person	NN
cord-026340-2nf97zvc	8	10	via	via	IN
cord-026340-2nf97zvc	8	11	aerosol	aerosol	NN
cord-026340-2nf97zvc	8	12	droplets	droplet	NNS
cord-026340-2nf97zvc	8	13	when	when	WRB
cord-026340-2nf97zvc	8	14	the	the	DT
cord-026340-2nf97zvc	8	15	person	person	NN
cord-026340-2nf97zvc	8	16	coughs	cough	VBZ
cord-026340-2nf97zvc	8	17	,	,	,
cord-026340-2nf97zvc	8	18	sneezes	sneeze	VBZ
cord-026340-2nf97zvc	8	19	,	,	,
cord-026340-2nf97zvc	8	20	or	or	CC
cord-026340-2nf97zvc	8	21	speaks	speak	VBZ
cord-026340-2nf97zvc	8	22	.	.	.
cord-026340-2nf97zvc	9	1	To	to	TO
cord-026340-2nf97zvc	9	2	limit	limit	VB
cord-026340-2nf97zvc	9	3	such	such	PDT
cord-026340-2nf97zvc	9	4	a	a	DT
cord-026340-2nf97zvc	9	5	transmission	transmission	NN
cord-026340-2nf97zvc	9	6	,	,	,
cord-026340-2nf97zvc	9	7	World	World	NNP
cord-026340-2nf97zvc	9	8	Health	Health	NNP
cord-026340-2nf97zvc	9	9	Organization	Organization	NNP
cord-026340-2nf97zvc	9	10	(	(	-LRB-
cord-026340-2nf97zvc	9	11	WHO	who	WP
cord-026340-2nf97zvc	9	12	)	)	-RRB-
cord-026340-2nf97zvc	9	13	has	have	VBZ
cord-026340-2nf97zvc	9	14	recommended	recommend	VBN
cord-026340-2nf97zvc	9	15	people	people	NNS
cord-026340-2nf97zvc	9	16	to	to	TO
cord-026340-2nf97zvc	9	17	wear	wear	VB
cord-026340-2nf97zvc	9	18	masks	mask	NNS
cord-026340-2nf97zvc	9	19	and	and	CC
cord-026340-2nf97zvc	9	20	physically	physically	RB
cord-026340-2nf97zvc	9	21	distance	distance	VBP
cord-026340-2nf97zvc	9	22	themselves	-PRON-	PRP
cord-026340-2nf97zvc	9	23	by	by	IN
cord-026340-2nf97zvc	9	24	staying	stay	VBG
cord-026340-2nf97zvc	9	25	at	at	RB
cord-026340-2nf97zvc	9	26	least	least	JJS
cord-026340-2nf97zvc	9	27	1	1	CD
cord-026340-2nf97zvc	9	28	m	m	NN
cord-026340-2nf97zvc	9	29	(	(	-LRB-
cord-026340-2nf97zvc	9	30	3	3	CD
cord-026340-2nf97zvc	9	31	feet	foot	NNS
cord-026340-2nf97zvc	9	32	)	)	-RRB-
cord-026340-2nf97zvc	9	33	away	away	RB
cord-026340-2nf97zvc	9	34	from	from	IN
cord-026340-2nf97zvc	9	35	others	other	NNS
cord-026340-2nf97zvc	9	36	.	.	.
cord-026340-2nf97zvc	10	1	As	as	IN
cord-026340-2nf97zvc	10	2	aerosol	aerosol	NN
cord-026340-2nf97zvc	10	3	droplets	droplet	NNS
cord-026340-2nf97zvc	10	4	(	(	-LRB-
cord-026340-2nf97zvc	10	5	by	by	IN
cord-026340-2nf97zvc	10	6	cough	cough	NN
cord-026340-2nf97zvc	10	7	or	or	CC
cord-026340-2nf97zvc	10	8	sneeze	sneeze	VB
cord-026340-2nf97zvc	10	9	)	)	-RRB-
cord-026340-2nf97zvc	10	10	land	land	NN
cord-026340-2nf97zvc	10	11	on	on	IN
cord-026340-2nf97zvc	10	12	objects	object	NNS
cord-026340-2nf97zvc	10	13	and	and	CC
cord-026340-2nf97zvc	10	14	surfaces	surface	NNS
cord-026340-2nf97zvc	10	15	around	around	IN
cord-026340-2nf97zvc	10	16	the	the	DT
cord-026340-2nf97zvc	10	17	person	person	NN
cord-026340-2nf97zvc	10	18	such	such	JJ
cord-026340-2nf97zvc	10	19	as	as	IN
cord-026340-2nf97zvc	10	20	tables	table	NNS
cord-026340-2nf97zvc	10	21	,	,	,
cord-026340-2nf97zvc	10	22	doorknobs	doorknob	NNS
cord-026340-2nf97zvc	10	23	and	and	CC
cord-026340-2nf97zvc	10	24	handrails	handrail	NNS
cord-026340-2nf97zvc	10	25	,	,	,
cord-026340-2nf97zvc	10	26	and	and	CC
cord-026340-2nf97zvc	10	27	remain	remain	VBP
cord-026340-2nf97zvc	10	28	active	active	JJ
cord-026340-2nf97zvc	10	29	on	on	IN
cord-026340-2nf97zvc	10	30	these	these	DT
cord-026340-2nf97zvc	10	31	surfaces	surface	NNS
cord-026340-2nf97zvc	10	32	for	for	IN
cord-026340-2nf97zvc	10	33	hours	hour	NNS
cord-026340-2nf97zvc	10	34	to	to	IN
cord-026340-2nf97zvc	10	35	days	day	NNS
cord-026340-2nf97zvc	10	36	,	,	,
cord-026340-2nf97zvc	10	37	people	people	NNS
cord-026340-2nf97zvc	10	38	are	be	VBP
cord-026340-2nf97zvc	10	39	advised	advise	VBN
cord-026340-2nf97zvc	10	40	to	to	TO
cord-026340-2nf97zvc	10	41	use	use	VB
cord-026340-2nf97zvc	10	42	soaps	soap	NNS
cord-026340-2nf97zvc	10	43	for	for	IN
cord-026340-2nf97zvc	10	44	at	at	RB
cord-026340-2nf97zvc	10	45	least	least	RBS
cord-026340-2nf97zvc	10	46	20	20	CD
cord-026340-2nf97zvc	10	47	s.	s.	NN
cord-026340-2nf97zvc	10	48	and	and	CC
cord-026340-2nf97zvc	10	49	alcohol	alcohol	NN
cord-026340-2nf97zvc	10	50	-	-	HYPH
cord-026340-2nf97zvc	10	51	based	base	VBN
cord-026340-2nf97zvc	10	52	sanitizers	sanitizer	NNS
cord-026340-2nf97zvc	10	53	as	as	RB
cord-026340-2nf97zvc	10	54	well	well	RB
cord-026340-2nf97zvc	10	55	.	.	.
cord-026340-2nf97zvc	11	1	As	as	IN
cord-026340-2nf97zvc	11	2	the	the	DT
cord-026340-2nf97zvc	11	3	public	public	NN
cord-026340-2nf97zvc	11	4	made	make	VBD
cord-026340-2nf97zvc	11	5	efforts	effort	NNS
cord-026340-2nf97zvc	11	6	,	,	,
cord-026340-2nf97zvc	11	7	clinicians	clinician	NNS
cord-026340-2nf97zvc	11	8	and	and	CC
cord-026340-2nf97zvc	11	9	researchers	researcher	NNS
cord-026340-2nf97zvc	11	10	investigated	investigate	VBD
cord-026340-2nf97zvc	11	11	and	and	CC
cord-026340-2nf97zvc	11	12	found	find	VBD
cord-026340-2nf97zvc	11	13	that	that	IN
cord-026340-2nf97zvc	11	14	drugs	drug	NNS
cord-026340-2nf97zvc	11	15	which	which	WDT
cord-026340-2nf97zvc	11	16	were	be	VBD
cord-026340-2nf97zvc	11	17	initially	initially	RB
cord-026340-2nf97zvc	11	18	used	use	VBN
cord-026340-2nf97zvc	11	19	to	to	TO
cord-026340-2nf97zvc	11	20	treat	treat	VB
cord-026340-2nf97zvc	11	21	other	other	JJ
cord-026340-2nf97zvc	11	22	diseases	disease	NNS
cord-026340-2nf97zvc	11	23	may	may	MD
cord-026340-2nf97zvc	11	24	work	work	VB
cord-026340-2nf97zvc	11	25	as	as	IN
cord-026340-2nf97zvc	11	26	a	a	DT
cord-026340-2nf97zvc	11	27	treatment	treatment	NN
cord-026340-2nf97zvc	11	28	option	option	NN
cord-026340-2nf97zvc	11	29	for	for	IN
cord-026340-2nf97zvc	11	30	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	11	31	.	.	.
cord-026340-2nf97zvc	12	1	One	one	CD
cord-026340-2nf97zvc	12	2	of	of	IN
cord-026340-2nf97zvc	12	3	those	those	DT
cord-026340-2nf97zvc	12	4	drugs	drug	NNS
cord-026340-2nf97zvc	12	5	was	be	VBD
cord-026340-2nf97zvc	12	6	Chloroquine	Chloroquine	NNP
cord-026340-2nf97zvc	12	7	and	and	CC
cord-026340-2nf97zvc	12	8	its	-PRON-	PRP$
cord-026340-2nf97zvc	12	9	related	related	JJ
cord-026340-2nf97zvc	12	10	derivative	derivative	NN
cord-026340-2nf97zvc	12	11	called	call	VBN
cord-026340-2nf97zvc	12	12	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	12	13	.	.	.
cord-026340-2nf97zvc	13	1	In	in	IN
cord-026340-2nf97zvc	13	2	this	this	DT
cord-026340-2nf97zvc	13	3	review	review	NN
cord-026340-2nf97zvc	13	4	article	article	NN
cord-026340-2nf97zvc	13	5	,	,	,
cord-026340-2nf97zvc	13	6	we	-PRON-	PRP
cord-026340-2nf97zvc	13	7	have	have	VBP
cord-026340-2nf97zvc	13	8	systematically	systematically	RB
cord-026340-2nf97zvc	13	9	searched	search	VBN
cord-026340-2nf97zvc	13	10	for	for	IN
cord-026340-2nf97zvc	13	11	details	detail	NNS
cord-026340-2nf97zvc	13	12	of	of	IN
cord-026340-2nf97zvc	13	13	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	13	14	pandemic	pandemic	NN
cord-026340-2nf97zvc	13	15	till	till	IN
cord-026340-2nf97zvc	13	16	May	May	NNP
cord-026340-2nf97zvc	13	17	2020	2020	CD
cord-026340-2nf97zvc	13	18	and	and	CC
cord-026340-2nf97zvc	13	19	assembled	assemble	VBD
cord-026340-2nf97zvc	13	20	few	few	JJ
cord-026340-2nf97zvc	13	21	data	datum	NNS
cord-026340-2nf97zvc	13	22	pertaining	pertain	VBG
cord-026340-2nf97zvc	13	23	to	to	IN
cord-026340-2nf97zvc	13	24	(	(	-LRB-
cord-026340-2nf97zvc	13	25	i	i	NN
cord-026340-2nf97zvc	13	26	)	)	-RRB-
cord-026340-2nf97zvc	13	27	Corona	Corona	NNP
cord-026340-2nf97zvc	13	28	viruses	virus	NNS
cord-026340-2nf97zvc	13	29	;	;	,
cord-026340-2nf97zvc	13	30	(	(	-LRB-
cord-026340-2nf97zvc	13	31	ii	ii	NN
cord-026340-2nf97zvc	13	32	)	)	-RRB-
cord-026340-2nf97zvc	14	1	SARS	SARS	NNP
cord-026340-2nf97zvc	14	2	-	-	HYPH
cord-026340-2nf97zvc	14	3	CoV2	CoV2	NNP
cord-026340-2nf97zvc	14	4	,	,	,
cord-026340-2nf97zvc	14	5	the	the	DT
cord-026340-2nf97zvc	14	6	virus	virus	NN
cord-026340-2nf97zvc	14	7	that	that	WDT
cord-026340-2nf97zvc	14	8	causes	cause	VBZ
cord-026340-2nf97zvc	14	9	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	14	10	’	'	''
cord-026340-2nf97zvc	14	11	and	and	CC
cord-026340-2nf97zvc	14	12	(	(	-LRB-
cord-026340-2nf97zvc	14	13	iii	iii	NN
cord-026340-2nf97zvc	14	14	)	)	-RRB-
cord-026340-2nf97zvc	15	1	How	how	WRB
cord-026340-2nf97zvc	15	2	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	15	3	and	and	CC
cord-026340-2nf97zvc	15	4	hydroxychloroquine	hydroxychloroquine	NNP
cord-026340-2nf97zvc	15	5	mediates	mediate	VBZ
cord-026340-2nf97zvc	15	6	anti	anti	JJ
cord-026340-2nf97zvc	15	7	-	-	JJ
cord-026340-2nf97zvc	15	8	viral	viral	JJ
cord-026340-2nf97zvc	15	9	effect	effect	NN
cord-026340-2nf97zvc	15	10	in	in	IN
cord-026340-2nf97zvc	15	11	both	both	CC
cord-026340-2nf97zvc	15	12	prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	15	13	and	and	CC
cord-026340-2nf97zvc	15	14	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	15	15	setting	setting	NN
cord-026340-2nf97zvc	15	16	.	.	.
cord-026340-2nf97zvc	16	1	These	these	DT
cord-026340-2nf97zvc	16	2	data	datum	NNS
cord-026340-2nf97zvc	16	3	have	have	VBP
cord-026340-2nf97zvc	16	4	been	be	VBN
cord-026340-2nf97zvc	16	5	acquired	acquire	VBN
cord-026340-2nf97zvc	16	6	mostly	mostly	RB
cord-026340-2nf97zvc	16	7	from	from	IN
cord-026340-2nf97zvc	16	8	PubMed	PubMed	NNP
cord-026340-2nf97zvc	16	9	and	and	CC
cord-026340-2nf97zvc	16	10	websites	website	NNS
cord-026340-2nf97zvc	16	11	of	of	IN
cord-026340-2nf97zvc	16	12	WHO	WHO	NNP
cord-026340-2nf97zvc	16	13	and	and	CC
cord-026340-2nf97zvc	16	14	Indian	Indian	NNP
cord-026340-2nf97zvc	16	15	Council	Council	NNP
cord-026340-2nf97zvc	16	16	for	for	IN
cord-026340-2nf97zvc	16	17	Medical	Medical	NNP
cord-026340-2nf97zvc	16	18	Research	Research	NNP
cord-026340-2nf97zvc	16	19	(	(	-LRB-
cord-026340-2nf97zvc	16	20	ICMR	ICMR	NNP
cord-026340-2nf97zvc	16	21	)	)	-RRB-
cord-026340-2nf97zvc	16	22	.	.	.
cord-026340-2nf97zvc	17	1	We	-PRON-	PRP
cord-026340-2nf97zvc	17	2	did	do	VBD
cord-026340-2nf97zvc	17	3	a	a	DT
cord-026340-2nf97zvc	17	4	systematic	systematic	JJ
cord-026340-2nf97zvc	17	5	search	search	NN
cord-026340-2nf97zvc	17	6	and	and	CC
cord-026340-2nf97zvc	17	7	found	find	VBD
cord-026340-2nf97zvc	17	8	that	that	IN
cord-026340-2nf97zvc	17	9	the	the	DT
cord-026340-2nf97zvc	17	10	properties	property	NNS
cord-026340-2nf97zvc	17	11	of	of	IN
cord-026340-2nf97zvc	17	12	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	17	13	are	be	VBP
cord-026340-2nf97zvc	17	14	very	very	RB
cord-026340-2nf97zvc	17	15	much	much	RB
cord-026340-2nf97zvc	17	16	essential	essential	JJ
cord-026340-2nf97zvc	17	17	for	for	IN
cord-026340-2nf97zvc	17	18	the	the	DT
cord-026340-2nf97zvc	17	19	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	17	20	scenario	scenario	NN
cord-026340-2nf97zvc	17	21	.	.	.
cord-026340-2nf97zvc	18	1	We	-PRON-	PRP
cord-026340-2nf97zvc	18	2	also	also	RB
cord-026340-2nf97zvc	18	3	bring	bring	VBP
cord-026340-2nf97zvc	18	4	to	to	IN
cord-026340-2nf97zvc	18	5	you	-PRON-	PRP
cord-026340-2nf97zvc	18	6	some	some	DT
cord-026340-2nf97zvc	18	7	evidence	evidence	NN
cord-026340-2nf97zvc	18	8	that	that	IN
cord-026340-2nf97zvc	18	9	the	the	DT
cord-026340-2nf97zvc	18	10	anti	anti	JJ
cord-026340-2nf97zvc	18	11	-	-	JJ
cord-026340-2nf97zvc	18	12	lysosomal	lysosomal	JJ
cord-026340-2nf97zvc	18	13	activity	activity	NN
cord-026340-2nf97zvc	18	14	of	of	IN
cord-026340-2nf97zvc	18	15	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	18	16	may	may	MD
cord-026340-2nf97zvc	18	17	be	be	VB
cord-026340-2nf97zvc	18	18	increased	increase	VBN
cord-026340-2nf97zvc	18	19	by	by	IN
cord-026340-2nf97zvc	18	20	botanicals	botanical	NNS
cord-026340-2nf97zvc	18	21	like	like	IN
cord-026340-2nf97zvc	18	22	betulinic	betulinic	JJ
cord-026340-2nf97zvc	18	23	acid	acid	NN
cord-026340-2nf97zvc	18	24	.	.	.
cord-026340-2nf97zvc	19	1	Viruses	virus	NNS
cord-026340-2nf97zvc	19	2	are	be	VBP
cord-026340-2nf97zvc	19	3	submicroscopic	submicroscopic	JJ
cord-026340-2nf97zvc	19	4	infectious	infectious	JJ
cord-026340-2nf97zvc	19	5	particles	particle	NNS
cord-026340-2nf97zvc	19	6	with	with	IN
cord-026340-2nf97zvc	19	7	the	the	DT
cord-026340-2nf97zvc	19	8	capacity	capacity	NN
cord-026340-2nf97zvc	19	9	to	to	TO
cord-026340-2nf97zvc	19	10	infect	infect	VB
cord-026340-2nf97zvc	19	11	bacteria	bacteria	NNS
cord-026340-2nf97zvc	19	12	,	,	,
cord-026340-2nf97zvc	19	13	algae	algae	NN
cord-026340-2nf97zvc	19	14	,	,	,
cord-026340-2nf97zvc	19	15	plants	plant	NNS
cord-026340-2nf97zvc	19	16	,	,	,
cord-026340-2nf97zvc	19	17	animals	animal	NNS
cord-026340-2nf97zvc	19	18	and	and	CC
cord-026340-2nf97zvc	19	19	humans	human	NNS
cord-026340-2nf97zvc	19	20	.	.	.
cord-026340-2nf97zvc	20	1	These	these	DT
cord-026340-2nf97zvc	20	2	can	can	MD
cord-026340-2nf97zvc	20	3	be	be	VB
cord-026340-2nf97zvc	20	4	found	find	VBN
cord-026340-2nf97zvc	20	5	in	in	IN
cord-026340-2nf97zvc	20	6	every	every	DT
cord-026340-2nf97zvc	20	7	ecosystem	ecosystem	NN
cord-026340-2nf97zvc	20	8	on	on	IN
cord-026340-2nf97zvc	20	9	earth	earth	NN
cord-026340-2nf97zvc	20	10	.	.	.
cord-026340-2nf97zvc	21	1	There	there	EX
cord-026340-2nf97zvc	21	2	are	be	VBP
cord-026340-2nf97zvc	21	3	numerous	numerous	JJ
cord-026340-2nf97zvc	21	4	different	different	JJ
cord-026340-2nf97zvc	21	5	varieties	variety	NNS
cord-026340-2nf97zvc	21	6	of	of	IN
cord-026340-2nf97zvc	21	7	viruses	virus	NNS
cord-026340-2nf97zvc	21	8	and	and	CC
cord-026340-2nf97zvc	21	9	many	many	JJ
cord-026340-2nf97zvc	21	10	are	be	VBP
cord-026340-2nf97zvc	21	11	yet	yet	RB
cord-026340-2nf97zvc	21	12	to	to	TO
cord-026340-2nf97zvc	21	13	be	be	VB
cord-026340-2nf97zvc	21	14	discovered	discover	VBN
cord-026340-2nf97zvc	21	15	.	.	.
cord-026340-2nf97zvc	22	1	Viruses	virus	NNS
cord-026340-2nf97zvc	22	2	are	be	VBP
cord-026340-2nf97zvc	22	3	different	different	JJ
cord-026340-2nf97zvc	22	4	from	from	IN
cord-026340-2nf97zvc	22	5	other	other	JJ
cord-026340-2nf97zvc	22	6	living	live	VBG
cord-026340-2nf97zvc	22	7	organisms	organism	NNS
cord-026340-2nf97zvc	22	8	as	as	IN
cord-026340-2nf97zvc	22	9	these	these	DT
cord-026340-2nf97zvc	22	10	require	require	VBP
cord-026340-2nf97zvc	22	11	a	a	DT
cord-026340-2nf97zvc	22	12	host	host	NN
cord-026340-2nf97zvc	22	13	cell	cell	NN
cord-026340-2nf97zvc	22	14	to	to	TO
cord-026340-2nf97zvc	22	15	reproduce	reproduce	VB
cord-026340-2nf97zvc	22	16	.	.	.
cord-026340-2nf97zvc	23	1	When	when	WRB
cord-026340-2nf97zvc	23	2	virus	virus	NN
cord-026340-2nf97zvc	23	3	infects	infect	VBZ
cord-026340-2nf97zvc	23	4	a	a	DT
cord-026340-2nf97zvc	23	5	host	host	NN
cord-026340-2nf97zvc	23	6	cell	cell	NN
cord-026340-2nf97zvc	23	7	(	(	-LRB-
cord-026340-2nf97zvc	23	8	or	or	CC
cord-026340-2nf97zvc	23	9	the	the	DT
cord-026340-2nf97zvc	23	10	virus	virus	NN
cord-026340-2nf97zvc	23	11	enters	enter	VBZ
cord-026340-2nf97zvc	23	12	a	a	DT
cord-026340-2nf97zvc	23	13	living	live	VBG
cord-026340-2nf97zvc	23	14	organism	organism	NN
cord-026340-2nf97zvc	23	15	)	)	-RRB-
cord-026340-2nf97zvc	23	16	,	,	,
cord-026340-2nf97zvc	23	17	the	the	DT
cord-026340-2nf97zvc	23	18	host	host	NN
cord-026340-2nf97zvc	23	19	cell	cell	NN
cord-026340-2nf97zvc	23	20	gets	get	VBZ
cord-026340-2nf97zvc	23	21	'	'	``
cord-026340-2nf97zvc	23	22	enslaved	enslave	VBN
cord-026340-2nf97zvc	23	23	'	'	''
cord-026340-2nf97zvc	23	24	to	to	IN
cord-026340-2nf97zvc	23	25	the	the	DT
cord-026340-2nf97zvc	23	26	virus	virus	NN
cord-026340-2nf97zvc	23	27	and	and	CC
cord-026340-2nf97zvc	23	28	synthesizes	synthesize	VBZ
cord-026340-2nf97zvc	23	29	thousands	thousand	NNS
cord-026340-2nf97zvc	23	30	of	of	IN
cord-026340-2nf97zvc	23	31	identical	identical	JJ
cord-026340-2nf97zvc	23	32	copies	copy	NNS
cord-026340-2nf97zvc	23	33	of	of	IN
cord-026340-2nf97zvc	23	34	the	the	DT
cord-026340-2nf97zvc	23	35	original	original	JJ
cord-026340-2nf97zvc	23	36	virus	virus	NN
cord-026340-2nf97zvc	23	37	.	.	.
cord-026340-2nf97zvc	24	1	Thereafter	thereafter	RB
cord-026340-2nf97zvc	24	2	,	,	,
cord-026340-2nf97zvc	24	3	the	the	DT
cord-026340-2nf97zvc	24	4	host	host	NN
cord-026340-2nf97zvc	24	5	cell	cell	NN
cord-026340-2nf97zvc	24	6	dies	die	VBZ
cord-026340-2nf97zvc	24	7	in	in	IN
cord-026340-2nf97zvc	24	8	the	the	DT
cord-026340-2nf97zvc	24	9	process	process	NN
cord-026340-2nf97zvc	24	10	of	of	IN
cord-026340-2nf97zvc	24	11	releasing	release	VBG
cord-026340-2nf97zvc	24	12	newly	newly	RB
cord-026340-2nf97zvc	24	13	synthesized	synthesize	VBN
cord-026340-2nf97zvc	24	14	viral	viral	JJ
cord-026340-2nf97zvc	24	15	particles	particle	NNS
cord-026340-2nf97zvc	24	16	.	.	.
cord-026340-2nf97zvc	25	1	A	a	DT
cord-026340-2nf97zvc	25	2	complete	complete	JJ
cord-026340-2nf97zvc	25	3	virus	virus	NN
cord-026340-2nf97zvc	25	4	basically	basically	RB
cord-026340-2nf97zvc	25	5	exists	exist	VBZ
cord-026340-2nf97zvc	25	6	as	as	IN
cord-026340-2nf97zvc	25	7	'	'	``
cord-026340-2nf97zvc	25	8	virions	virion	NNS
cord-026340-2nf97zvc	25	9	'	'	''
cord-026340-2nf97zvc	25	10	comprising	comprising	NN
cord-026340-2nf97zvc	25	11	of	of	IN
cord-026340-2nf97zvc	25	12	either	either	DT
cord-026340-2nf97zvc	25	13	DNA	DNA	NNP
cord-026340-2nf97zvc	25	14	or	or	CC
cord-026340-2nf97zvc	25	15	RNA	RNA	NNP
cord-026340-2nf97zvc	25	16	as	as	IN
cord-026340-2nf97zvc	25	17	genetic	genetic	JJ
cord-026340-2nf97zvc	25	18	material	material	NN
cord-026340-2nf97zvc	25	19	encased	encase	VBN
cord-026340-2nf97zvc	25	20	in	in	IN
cord-026340-2nf97zvc	25	21	a	a	DT
cord-026340-2nf97zvc	25	22	protein	protein	NN
cord-026340-2nf97zvc	25	23	or	or	CC
cord-026340-2nf97zvc	25	24	sometimes	sometimes	RB
cord-026340-2nf97zvc	25	25	lipid	lipid	VBG
cord-026340-2nf97zvc	25	26	coat	coat	NN
cord-026340-2nf97zvc	25	27	.	.	.
cord-026340-2nf97zvc	26	1	The	the	DT
cord-026340-2nf97zvc	26	2	genetic	genetic	JJ
cord-026340-2nf97zvc	26	3	material	material	NN
cord-026340-2nf97zvc	26	4	may	may	MD
cord-026340-2nf97zvc	26	5	be	be	VB
cord-026340-2nf97zvc	26	6	single	single	JJ
cord-026340-2nf97zvc	26	7	stranded	stranded	JJ
cord-026340-2nf97zvc	26	8	or	or	CC
cord-026340-2nf97zvc	26	9	double	double	JJ
cord-026340-2nf97zvc	26	10	stranded	strand	VBN
cord-026340-2nf97zvc	26	11	,	,	,
cord-026340-2nf97zvc	26	12	linear	linear	JJ
cord-026340-2nf97zvc	26	13	or	or	CC
cord-026340-2nf97zvc	26	14	circular	circular	JJ
cord-026340-2nf97zvc	26	15	.	.	.
cord-026340-2nf97zvc	27	1	The	the	DT
cord-026340-2nf97zvc	27	2	amount	amount	NN
cord-026340-2nf97zvc	27	3	and	and	CC
cord-026340-2nf97zvc	27	4	arrangement	arrangement	NN
cord-026340-2nf97zvc	27	5	of	of	IN
cord-026340-2nf97zvc	27	6	the	the	DT
cord-026340-2nf97zvc	27	7	genetic	genetic	JJ
cord-026340-2nf97zvc	27	8	material	material	NN
cord-026340-2nf97zvc	27	9	and	and	CC
cord-026340-2nf97zvc	27	10	proteins	protein	NNS
cord-026340-2nf97zvc	27	11	determines	determine	VBZ
cord-026340-2nf97zvc	27	12	the	the	DT
cord-026340-2nf97zvc	27	13	shape	shape	NN
cord-026340-2nf97zvc	27	14	and	and	CC
cord-026340-2nf97zvc	27	15	sizes	size	NNS
cord-026340-2nf97zvc	27	16	of	of	IN
cord-026340-2nf97zvc	27	17	the	the	DT
cord-026340-2nf97zvc	27	18	viruses	virus	NNS
cord-026340-2nf97zvc	27	19	.	.	.
cord-026340-2nf97zvc	28	1	Viruses	virus	NNS
cord-026340-2nf97zvc	28	2	thus	thus	RB
cord-026340-2nf97zvc	28	3	have	have	VBP
cord-026340-2nf97zvc	28	4	complicated	complicate	VBN
cord-026340-2nf97zvc	28	5	shapes	shape	NNS
cord-026340-2nf97zvc	28	6	ranging	range	VBG
cord-026340-2nf97zvc	28	7	from	from	IN
cord-026340-2nf97zvc	28	8	helical	helical	JJ
cord-026340-2nf97zvc	28	9	to	to	IN
cord-026340-2nf97zvc	28	10	icosahedral	icosahedral	JJ
cord-026340-2nf97zvc	28	11	forms	form	NNS
cord-026340-2nf97zvc	28	12	.	.	.
cord-026340-2nf97zvc	29	1	How	how	WRB
cord-026340-2nf97zvc	29	2	a	a	DT
cord-026340-2nf97zvc	29	3	virus	virus	NN
cord-026340-2nf97zvc	29	4	originated	originate	VBD
cord-026340-2nf97zvc	29	5	on	on	IN
cord-026340-2nf97zvc	29	6	earth	earth	NN
cord-026340-2nf97zvc	29	7	is	be	VBZ
cord-026340-2nf97zvc	29	8	still	still	RB
cord-026340-2nf97zvc	29	9	a	a	DT
cord-026340-2nf97zvc	29	10	mystery	mystery	NN
cord-026340-2nf97zvc	29	11	and	and	CC
cord-026340-2nf97zvc	29	12	it	-PRON-	PRP
cord-026340-2nf97zvc	29	13	has	have	VBZ
cord-026340-2nf97zvc	29	14	been	be	VBN
cord-026340-2nf97zvc	29	15	thought	think	VBN
cord-026340-2nf97zvc	29	16	that	that	IN
cord-026340-2nf97zvc	29	17	these	these	DT
cord-026340-2nf97zvc	29	18	were	be	VBD
cord-026340-2nf97zvc	29	19	formed	form	VBN
cord-026340-2nf97zvc	29	20	from	from	IN
cord-026340-2nf97zvc	29	21	DNA	dna	NN
cord-026340-2nf97zvc	29	22	fragments	fragment	NNS
cord-026340-2nf97zvc	29	23	that	that	WDT
cord-026340-2nf97zvc	29	24	once	once	RB
cord-026340-2nf97zvc	29	25	escaped	escape	VBD
cord-026340-2nf97zvc	29	26	from	from	IN
cord-026340-2nf97zvc	29	27	a	a	DT
cord-026340-2nf97zvc	29	28	cell	cell	NN
cord-026340-2nf97zvc	29	29	.	.	.
cord-026340-2nf97zvc	30	1	With	with	IN
cord-026340-2nf97zvc	30	2	time	time	NN
cord-026340-2nf97zvc	30	3	,	,	,
cord-026340-2nf97zvc	30	4	many	many	JJ
cord-026340-2nf97zvc	30	5	viruses	virus	NNS
cord-026340-2nf97zvc	30	6	learned	learn	VBD
cord-026340-2nf97zvc	30	7	to	to	TO
cord-026340-2nf97zvc	30	8	evade	evade	VB
cord-026340-2nf97zvc	30	9	host	host	NN
cord-026340-2nf97zvc	30	10	immune	immune	JJ
cord-026340-2nf97zvc	30	11	systems	system	NNS
cord-026340-2nf97zvc	30	12	via	via	IN
cord-026340-2nf97zvc	30	13	efficient	efficient	JJ
cord-026340-2nf97zvc	30	14	strategies	strategy	NNS
cord-026340-2nf97zvc	30	15	producing	produce	VBG
cord-026340-2nf97zvc	30	16	diseases	disease	NNS
cord-026340-2nf97zvc	30	17	for	for	IN
cord-026340-2nf97zvc	30	18	both	both	DT
cord-026340-2nf97zvc	30	19	humans	human	NNS
cord-026340-2nf97zvc	30	20	and	and	CC
cord-026340-2nf97zvc	30	21	animals	animal	NNS
cord-026340-2nf97zvc	30	22	.	.	.
cord-026340-2nf97zvc	31	1	However	however	RB
cord-026340-2nf97zvc	31	2	,	,	,
cord-026340-2nf97zvc	31	3	the	the	DT
cord-026340-2nf97zvc	31	4	last	last	JJ
cord-026340-2nf97zvc	31	5	several	several	JJ
cord-026340-2nf97zvc	31	6	years	year	NNS
cord-026340-2nf97zvc	31	7	has	have	VBZ
cord-026340-2nf97zvc	31	8	witnessed	witness	VBN
cord-026340-2nf97zvc	31	9	a	a	DT
cord-026340-2nf97zvc	31	10	surge	surge	NN
cord-026340-2nf97zvc	31	11	in	in	IN
cord-026340-2nf97zvc	31	12	many	many	JJ
cord-026340-2nf97zvc	31	13	new	new	JJ
cord-026340-2nf97zvc	31	14	viruses	virus	NNS
cord-026340-2nf97zvc	31	15	especially	especially	RB
cord-026340-2nf97zvc	31	16	those	those	DT
cord-026340-2nf97zvc	31	17	from	from	IN
cord-026340-2nf97zvc	31	18	animals	animal	NNS
cord-026340-2nf97zvc	31	19	by	by	IN
cord-026340-2nf97zvc	31	20	a	a	DT
cord-026340-2nf97zvc	31	21	process	process	NN
cord-026340-2nf97zvc	31	22	called	call	VBN
cord-026340-2nf97zvc	31	23	zoonosis	zoonosis	NN
cord-026340-2nf97zvc	31	24	.	.	.
cord-026340-2nf97zvc	32	1	This	this	DT
cord-026340-2nf97zvc	32	2	basically	basically	RB
cord-026340-2nf97zvc	32	3	occurred	occur	VBD
cord-026340-2nf97zvc	32	4	due	due	IN
cord-026340-2nf97zvc	32	5	to	to	IN
cord-026340-2nf97zvc	32	6	intrusion	intrusion	NN
cord-026340-2nf97zvc	32	7	of	of	IN
cord-026340-2nf97zvc	32	8	human	human	JJ
cord-026340-2nf97zvc	32	9	activity	activity	NN
cord-026340-2nf97zvc	32	10	into	into	IN
cord-026340-2nf97zvc	32	11	wildlife	wildlife	NN
cord-026340-2nf97zvc	32	12	habitats	habitat	NNS
cord-026340-2nf97zvc	32	13	.	.	.
cord-026340-2nf97zvc	33	1	An	an	DT
cord-026340-2nf97zvc	33	2	example	example	NN
cord-026340-2nf97zvc	33	3	of	of	IN
cord-026340-2nf97zvc	33	4	Ranjana	Ranjana	NNP
cord-026340-2nf97zvc	33	5	Singh	Singh	NNP
cord-026340-2nf97zvc	33	6	and	and	CC
cord-026340-2nf97zvc	33	7	Viji	Viji	NNP
cord-026340-2nf97zvc	33	8	Vijayan	Vijayan	NNP
cord-026340-2nf97zvc	33	9	have	have	VBP
cord-026340-2nf97zvc	33	10	contributed	contribute	VBN
cord-026340-2nf97zvc	33	11	equally	equally	RB
cord-026340-2nf97zvc	33	12	to	to	IN
cord-026340-2nf97zvc	33	13	this	this	DT
cord-026340-2nf97zvc	33	14	work	work	NN
cord-026340-2nf97zvc	33	15	.	.	.
cord-026340-2nf97zvc	34	1	this	this	DT
cord-026340-2nf97zvc	34	2	is	be	VBZ
cord-026340-2nf97zvc	34	3	deforestation	deforestation	NN
cord-026340-2nf97zvc	34	4	which	which	WDT
cord-026340-2nf97zvc	34	5	led	lead	VBD
cord-026340-2nf97zvc	34	6	to	to	IN
cord-026340-2nf97zvc	34	7	changes	change	NNS
cord-026340-2nf97zvc	34	8	in	in	IN
cord-026340-2nf97zvc	34	9	living	live	VBG
cord-026340-2nf97zvc	34	10	habitat	habitat	NN
cord-026340-2nf97zvc	34	11	of	of	IN
cord-026340-2nf97zvc	34	12	bats	bat	NNS
cord-026340-2nf97zvc	34	13	,	,	,
cord-026340-2nf97zvc	34	14	and	and	CC
cord-026340-2nf97zvc	34	15	infections	infection	NNS
cord-026340-2nf97zvc	34	16	from	from	IN
cord-026340-2nf97zvc	34	17	bats	bat	NNS
cord-026340-2nf97zvc	34	18	to	to	IN
cord-026340-2nf97zvc	34	19	other	other	JJ
cord-026340-2nf97zvc	34	20	organisms	organism	NNS
cord-026340-2nf97zvc	34	21	like	like	IN
cord-026340-2nf97zvc	34	22	palm	palm	NN
cord-026340-2nf97zvc	34	23	civets	civet	NNS
cord-026340-2nf97zvc	34	24	,	,	,
cord-026340-2nf97zvc	34	25	pangolins	pangolin	NNS
cord-026340-2nf97zvc	34	26	,	,	,
cord-026340-2nf97zvc	34	27	camels	camel	NNS
cord-026340-2nf97zvc	34	28	,	,	,
cord-026340-2nf97zvc	34	29	horses	horse	NNS
cord-026340-2nf97zvc	34	30	which	which	WDT
cord-026340-2nf97zvc	34	31	acted	act	VBD
cord-026340-2nf97zvc	34	32	as	as	IN
cord-026340-2nf97zvc	34	33	intermediary	intermediary	JJ
cord-026340-2nf97zvc	34	34	hosts	host	NNS
cord-026340-2nf97zvc	34	35	to	to	TO
cord-026340-2nf97zvc	34	36	infect	infect	VB
cord-026340-2nf97zvc	34	37	humans	human	NNS
cord-026340-2nf97zvc	34	38	.	.	.
cord-026340-2nf97zvc	35	1	The	the	DT
cord-026340-2nf97zvc	35	2	increased	increased	JJ
cord-026340-2nf97zvc	35	3	world	world	NN
cord-026340-2nf97zvc	35	4	-	-	HYPH
cord-026340-2nf97zvc	35	5	wide	wide	JJ
cord-026340-2nf97zvc	35	6	travel	travel	NN
cord-026340-2nf97zvc	35	7	is	be	VBZ
cord-026340-2nf97zvc	35	8	a	a	DT
cord-026340-2nf97zvc	35	9	reason	reason	NN
cord-026340-2nf97zvc	35	10	that	that	WDT
cord-026340-2nf97zvc	35	11	has	have	VBZ
cord-026340-2nf97zvc	35	12	accelerated	accelerate	VBN
cord-026340-2nf97zvc	35	13	the	the	DT
cord-026340-2nf97zvc	35	14	spread	spread	NN
cord-026340-2nf97zvc	35	15	of	of	IN
cord-026340-2nf97zvc	35	16	viruses	virus	NNS
cord-026340-2nf97zvc	35	17	.	.	.
cord-026340-2nf97zvc	36	1	For	for	IN
cord-026340-2nf97zvc	36	2	example	example	NN
cord-026340-2nf97zvc	36	3	,	,	,
cord-026340-2nf97zvc	36	4	the	the	DT
cord-026340-2nf97zvc	36	5	Avian	avian	JJ
cord-026340-2nf97zvc	36	6	flu	flu	NN
cord-026340-2nf97zvc	36	7	virus	virus	NN
cord-026340-2nf97zvc	36	8	H5N1	H5N1	NNP
cord-026340-2nf97zvc	36	9	was	be	VBD
cord-026340-2nf97zvc	36	10	transported	transport	VBN
cord-026340-2nf97zvc	36	11	from	from	IN
cord-026340-2nf97zvc	36	12	Asia	Asia	NNP
cord-026340-2nf97zvc	36	13	to	to	IN
cord-026340-2nf97zvc	36	14	Europe	Europe	NNP
cord-026340-2nf97zvc	36	15	by	by	IN
cord-026340-2nf97zvc	36	16	migratory	migratory	JJ
cord-026340-2nf97zvc	36	17	birds	bird	NNS
cord-026340-2nf97zvc	36	18	.	.	.
cord-026340-2nf97zvc	37	1	The	the	DT
cord-026340-2nf97zvc	37	2	AIDS	AIDS	NNP
cord-026340-2nf97zvc	37	3	pandemic	pandemic	NN
cord-026340-2nf97zvc	37	4	that	that	WDT
cord-026340-2nf97zvc	37	5	was	be	VBD
cord-026340-2nf97zvc	37	6	induced	induce	VBN
cord-026340-2nf97zvc	37	7	by	by	IN
cord-026340-2nf97zvc	37	8	human	human	JJ
cord-026340-2nf97zvc	37	9	immunodeficiency	immunodeficiency	NN
cord-026340-2nf97zvc	37	10	viruses	virus	NNS
cord-026340-2nf97zvc	37	11	(	(	-LRB-
cord-026340-2nf97zvc	37	12	HIV	HIV	NNP
cord-026340-2nf97zvc	37	13	)	)	-RRB-
cord-026340-2nf97zvc	37	14	was	be	VBD
cord-026340-2nf97zvc	37	15	originally	originally	RB
cord-026340-2nf97zvc	37	16	a	a	DT
cord-026340-2nf97zvc	37	17	zoonotic	zoonotic	JJ
cord-026340-2nf97zvc	37	18	transmission	transmission	NN
cord-026340-2nf97zvc	37	19	from	from	IN
cord-026340-2nf97zvc	37	20	monkeys	monkey	NNS
cord-026340-2nf97zvc	37	21	to	to	IN
cord-026340-2nf97zvc	37	22	humans	human	NNS
cord-026340-2nf97zvc	37	23	,	,	,
cord-026340-2nf97zvc	37	24	followed	follow	VBN
cord-026340-2nf97zvc	37	25	by	by	IN
cord-026340-2nf97zvc	37	26	efficient	efficient	JJ
cord-026340-2nf97zvc	37	27	further	further	JJ
cord-026340-2nf97zvc	37	28	distribution	distribution	NN
cord-026340-2nf97zvc	37	29	within	within	IN
cord-026340-2nf97zvc	37	30	the	the	DT
cord-026340-2nf97zvc	37	31	human	human	JJ
cord-026340-2nf97zvc	37	32	population	population	NN
cord-026340-2nf97zvc	37	33	(	(	-LRB-
cord-026340-2nf97zvc	37	34	Modrow	Modrow	NNP
cord-026340-2nf97zvc	37	35	et	et	FW
cord-026340-2nf97zvc	37	36	al	al	NNP
cord-026340-2nf97zvc	37	37	.	.	NNP
cord-026340-2nf97zvc	37	38	2013	2013	CD
cord-026340-2nf97zvc	37	39	)	)	-RRB-
cord-026340-2nf97zvc	37	40	.	.	.
cord-026340-2nf97zvc	38	1	The	the	DT
cord-026340-2nf97zvc	38	2	transmission	transmission	NN
cord-026340-2nf97zvc	38	3	of	of	IN
cord-026340-2nf97zvc	38	4	such	such	JJ
cord-026340-2nf97zvc	38	5	virus	virus	NN
cord-026340-2nf97zvc	38	6	can	can	MD
cord-026340-2nf97zvc	38	7	occur	occur	VB
cord-026340-2nf97zvc	38	8	by	by	IN
cord-026340-2nf97zvc	38	9	different	different	JJ
cord-026340-2nf97zvc	38	10	means	mean	NNS
cord-026340-2nf97zvc	38	11	like	like	IN
cord-026340-2nf97zvc	38	12	vectors	vector	NNS
cord-026340-2nf97zvc	38	13	,	,	,
cord-026340-2nf97zvc	38	14	respiratory	respiratory	JJ
cord-026340-2nf97zvc	38	15	droplets	droplet	NNS
cord-026340-2nf97zvc	38	16	,	,	,
cord-026340-2nf97zvc	38	17	feces	fece	NNS
cord-026340-2nf97zvc	38	18	,	,	,
cord-026340-2nf97zvc	38	19	blisters	blister	NNS
cord-026340-2nf97zvc	38	20	,	,	,
cord-026340-2nf97zvc	38	21	mucus	mucus	NN
cord-026340-2nf97zvc	38	22	,	,	,
cord-026340-2nf97zvc	38	23	sexual	sexual	JJ
cord-026340-2nf97zvc	38	24	contact	contact	NN
cord-026340-2nf97zvc	38	25	,	,	,
cord-026340-2nf97zvc	38	26	etc	etc	FW
cord-026340-2nf97zvc	38	27	.	.	.
cord-026340-2nf97zvc	39	1	Coronaviruses	Coronaviruses	NNP
cord-026340-2nf97zvc	39	2	(	(	-LRB-
cord-026340-2nf97zvc	39	3	CoVs	CoVs	NNP
cord-026340-2nf97zvc	39	4	)	)	-RRB-
cord-026340-2nf97zvc	39	5	are	be	VBP
cord-026340-2nf97zvc	39	6	a	a	DT
cord-026340-2nf97zvc	39	7	group	group	NN
cord-026340-2nf97zvc	39	8	of	of	IN
cord-026340-2nf97zvc	39	9	single	single	RB
cord-026340-2nf97zvc	39	10	-	-	HYPH
cord-026340-2nf97zvc	39	11	stranded	strand	VBN
cord-026340-2nf97zvc	39	12	RNA	RNA	NNP
cord-026340-2nf97zvc	39	13	viruses	virus	NNS
cord-026340-2nf97zvc	39	14	belonging	belong	VBG
cord-026340-2nf97zvc	39	15	to	to	IN
cord-026340-2nf97zvc	39	16	a	a	DT
cord-026340-2nf97zvc	39	17	sub	sub	JJ
cord-026340-2nf97zvc	39	18	-	-	JJ
cord-026340-2nf97zvc	39	19	family	family	NN
cord-026340-2nf97zvc	39	20	called	call	VBN
cord-026340-2nf97zvc	39	21	Coronaviridae	Coronaviridae	NNP
cord-026340-2nf97zvc	39	22	that	that	IN
cord-026340-2nf97zvc	39	23	together	together	RB
cord-026340-2nf97zvc	39	24	with	with	IN
cord-026340-2nf97zvc	39	25	Torovirinae	Torovirinae	NNP
cord-026340-2nf97zvc	39	26	form	form	NN
cord-026340-2nf97zvc	39	27	the	the	DT
cord-026340-2nf97zvc	39	28	Coronaviridae	Coronaviridae	NNP
cord-026340-2nf97zvc	39	29	family	family	NN
cord-026340-2nf97zvc	39	30	of	of	IN
cord-026340-2nf97zvc	39	31	the	the	DT
cord-026340-2nf97zvc	39	32	Nidovirales	Nidovirales	NNP
cord-026340-2nf97zvc	39	33	order	order	NN
cord-026340-2nf97zvc	39	34	.	.	.
cord-026340-2nf97zvc	40	1	These	these	DT
cord-026340-2nf97zvc	40	2	are	be	VBP
cord-026340-2nf97zvc	40	3	the	the	DT
cord-026340-2nf97zvc	40	4	largest	large	JJS
cord-026340-2nf97zvc	40	5	known	know	VBN
cord-026340-2nf97zvc	40	6	RNA	rna	NN
cord-026340-2nf97zvc	40	7	viruses	virus	NNS
cord-026340-2nf97zvc	40	8	with	with	IN
cord-026340-2nf97zvc	40	9	the	the	DT
cord-026340-2nf97zvc	40	10	potential	potential	NN
cord-026340-2nf97zvc	40	11	to	to	TO
cord-026340-2nf97zvc	40	12	infect	infect	VB
cord-026340-2nf97zvc	40	13	birds	bird	NNS
cord-026340-2nf97zvc	40	14	,	,	,
cord-026340-2nf97zvc	40	15	humans	human	NNS
cord-026340-2nf97zvc	40	16	and	and	CC
cord-026340-2nf97zvc	40	17	some	some	DT
cord-026340-2nf97zvc	40	18	other	other	JJ
cord-026340-2nf97zvc	40	19	vertebrates	vertebrate	NNS
cord-026340-2nf97zvc	40	20	.	.	.
cord-026340-2nf97zvc	41	1	Although	although	IN
cord-026340-2nf97zvc	41	2	the	the	DT
cord-026340-2nf97zvc	41	3	first	first	JJ
cord-026340-2nf97zvc	41	4	member	member	NN
cord-026340-2nf97zvc	41	5	of	of	IN
cord-026340-2nf97zvc	41	6	the	the	DT
cord-026340-2nf97zvc	41	7	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	41	8	family	family	NN
cord-026340-2nf97zvc	41	9	was	be	VBD
cord-026340-2nf97zvc	41	10	discovered	discover	VBN
cord-026340-2nf97zvc	41	11	in	in	IN
cord-026340-2nf97zvc	41	12	the	the	DT
cord-026340-2nf97zvc	41	13	1930s	1930	NNS
cord-026340-2nf97zvc	41	14	,	,	,
cord-026340-2nf97zvc	41	15	coronaviruses	coronaviruse	NNS
cord-026340-2nf97zvc	41	16	gained	gain	VBD
cord-026340-2nf97zvc	41	17	notoriety	notoriety	NN
cord-026340-2nf97zvc	41	18	with	with	IN
cord-026340-2nf97zvc	41	19	the	the	DT
cord-026340-2nf97zvc	41	20	severe	severe	JJ
cord-026340-2nf97zvc	41	21	acute	acute	JJ
cord-026340-2nf97zvc	41	22	respiratory	respiratory	JJ
cord-026340-2nf97zvc	41	23	syndrome	syndrome	NN
cord-026340-2nf97zvc	41	24	(	(	-LRB-
cord-026340-2nf97zvc	41	25	SARS	SARS	NNP
cord-026340-2nf97zvc	41	26	)	)	-RRB-
cord-026340-2nf97zvc	41	27	outbreak	outbreak	NN
cord-026340-2nf97zvc	41	28	in	in	IN
cord-026340-2nf97zvc	41	29	2002	2002	CD
cord-026340-2nf97zvc	42	1	(	(	-LRB-
cord-026340-2nf97zvc	42	2	Belouzard	Belouzard	NNP
cord-026340-2nf97zvc	42	3	et	et	NNP
cord-026340-2nf97zvc	42	4	al	al	NNP
cord-026340-2nf97zvc	42	5	.	.	NNP
cord-026340-2nf97zvc	42	6	2012	2012	CD
cord-026340-2nf97zvc	42	7	)	)	-RRB-
cord-026340-2nf97zvc	42	8	.	.	.
cord-026340-2nf97zvc	43	1	The	the	DT
cord-026340-2nf97zvc	43	2	International	International	NNP
cord-026340-2nf97zvc	43	3	Committee	Committee	NNP
cord-026340-2nf97zvc	43	4	on	on	IN
cord-026340-2nf97zvc	43	5	Taxonomy	Taxonomy	NNP
cord-026340-2nf97zvc	43	6	of	of	IN
cord-026340-2nf97zvc	43	7	Viruses	Viruses	NNPS
cord-026340-2nf97zvc	43	8	(	(	-LRB-
cord-026340-2nf97zvc	43	9	ICTV	ICTV	NNP
cord-026340-2nf97zvc	43	10	)	)	-RRB-
cord-026340-2nf97zvc	43	11	have	have	VBP
cord-026340-2nf97zvc	43	12	segregated	segregate	VBN
cord-026340-2nf97zvc	43	13	CoVs	CoVs	NNP
cord-026340-2nf97zvc	43	14	into	into	IN
cord-026340-2nf97zvc	43	15	four	four	CD
cord-026340-2nf97zvc	43	16	genera	genus	NNS
cord-026340-2nf97zvc	43	17	,	,	,
cord-026340-2nf97zvc	43	18	historically	historically	RB
cord-026340-2nf97zvc	43	19	based	base	VBN
cord-026340-2nf97zvc	43	20	on	on	IN
cord-026340-2nf97zvc	43	21	serological	serological	JJ
cord-026340-2nf97zvc	43	22	analysis	analysis	NN
cord-026340-2nf97zvc	43	23	and	and	CC
cord-026340-2nf97zvc	43	24	now	now	RB
cord-026340-2nf97zvc	43	25	on	on	IN
cord-026340-2nf97zvc	43	26	genetic	genetic	JJ
cord-026340-2nf97zvc	43	27	studies	study	NNS
cord-026340-2nf97zvc	43	28	:	:	:
cord-026340-2nf97zvc	43	29	α	α	NNP
cord-026340-2nf97zvc	43	30	,	,	,
cord-026340-2nf97zvc	43	31	β	β	NN
cord-026340-2nf97zvc	43	32	,	,	,
cord-026340-2nf97zvc	43	33	γ	γ	NNP
cord-026340-2nf97zvc	43	34	,	,	,
cord-026340-2nf97zvc	43	35	and	and	CC
cord-026340-2nf97zvc	43	36	δ	δ	NN
cord-026340-2nf97zvc	43	37	.	.	.
cord-026340-2nf97zvc	44	1	These	these	DT
cord-026340-2nf97zvc	44	2	viruses	virus	NNS
cord-026340-2nf97zvc	44	3	are	be	VBP
cord-026340-2nf97zvc	44	4	enveloped	envelop	VBN
cord-026340-2nf97zvc	44	5	,	,	,
cord-026340-2nf97zvc	44	6	spherical	spherical	JJ
cord-026340-2nf97zvc	44	7	and	and	CC
cord-026340-2nf97zvc	44	8	distinct	distinct	JJ
cord-026340-2nf97zvc	44	9	in	in	IN
cord-026340-2nf97zvc	44	10	appearance	appearance	NN
cord-026340-2nf97zvc	44	11	,	,	,
cord-026340-2nf97zvc	44	12	as	as	IN
cord-026340-2nf97zvc	44	13	they	-PRON-	PRP
cord-026340-2nf97zvc	44	14	possess	possess	VBP
cord-026340-2nf97zvc	44	15	club	club	NN
cord-026340-2nf97zvc	44	16	-	-	HYPH
cord-026340-2nf97zvc	44	17	shaped	shape	VBN
cord-026340-2nf97zvc	44	18	projections	projection	NNS
cord-026340-2nf97zvc	44	19	on	on	IN
cord-026340-2nf97zvc	44	20	their	-PRON-	PRP$
cord-026340-2nf97zvc	44	21	surface	surface	NN
cord-026340-2nf97zvc	44	22	.	.	.
cord-026340-2nf97zvc	45	1	The	the	DT
cord-026340-2nf97zvc	45	2	RNA	RNA	NNP
cord-026340-2nf97zvc	45	3	genome	genome	NN
cord-026340-2nf97zvc	45	4	of	of	IN
cord-026340-2nf97zvc	45	5	these	these	DT
cord-026340-2nf97zvc	45	6	viruses	virus	NNS
cord-026340-2nf97zvc	45	7	ranges	range	VBZ
cord-026340-2nf97zvc	45	8	from	from	IN
cord-026340-2nf97zvc	45	9	26,000	26,000	CD
cord-026340-2nf97zvc	45	10	to	to	TO
cord-026340-2nf97zvc	45	11	32,000	32,000	CD
cord-026340-2nf97zvc	45	12	bases	basis	NNS
cord-026340-2nf97zvc	45	13	(	(	-LRB-
cord-026340-2nf97zvc	45	14	longest	long	JJS
cord-026340-2nf97zvc	45	15	among	among	IN
cord-026340-2nf97zvc	45	16	RNA	RNA	NNP
cord-026340-2nf97zvc	45	17	viruses	virus	NNS
cord-026340-2nf97zvc	45	18	)	)	-RRB-
cord-026340-2nf97zvc	45	19	.	.	.
cord-026340-2nf97zvc	46	1	The	the	DT
cord-026340-2nf97zvc	46	2	genome	genome	NN
cord-026340-2nf97zvc	46	3	is	be	VBZ
cord-026340-2nf97zvc	46	4	packed	pack	VBN
cord-026340-2nf97zvc	46	5	into	into	IN
cord-026340-2nf97zvc	46	6	a	a	DT
cord-026340-2nf97zvc	46	7	helical	helical	JJ
cord-026340-2nf97zvc	46	8	nucleocapsid	nucleocapsid	NN
cord-026340-2nf97zvc	46	9	surrounded	surround	VBN
cord-026340-2nf97zvc	46	10	by	by	IN
cord-026340-2nf97zvc	46	11	a	a	DT
cord-026340-2nf97zvc	46	12	host	host	NN
cord-026340-2nf97zvc	46	13	-	-	HYPH
cord-026340-2nf97zvc	46	14	derived	derive	VBN
cord-026340-2nf97zvc	46	15	lipid	lipid	NN
cord-026340-2nf97zvc	46	16	bilayer	bilayer	NN
cord-026340-2nf97zvc	46	17	.	.	.
cord-026340-2nf97zvc	47	1	RNA	RNA	NNP
cord-026340-2nf97zvc	47	2	has	have	VBZ
cord-026340-2nf97zvc	47	3	a	a	DT
cord-026340-2nf97zvc	47	4	cap	cap	NN
cord-026340-2nf97zvc	47	5	structure	structure	NN
cord-026340-2nf97zvc	47	6	at	at	IN
cord-026340-2nf97zvc	47	7	the	the	DT
cord-026340-2nf97zvc	47	8	5′	5′	CD
cord-026340-2nf97zvc	47	9	end	end	NN
cord-026340-2nf97zvc	47	10	and	and	CC
cord-026340-2nf97zvc	47	11	multiple	multiple	JJ
cord-026340-2nf97zvc	47	12	poly	poly	NN
cord-026340-2nf97zvc	47	13	(	(	-LRB-
cord-026340-2nf97zvc	47	14	A	a	NN
cord-026340-2nf97zvc	47	15	)	)	-RRB-
cord-026340-2nf97zvc	47	16	tail	tail	NN
cord-026340-2nf97zvc	47	17	at	at	IN
cord-026340-2nf97zvc	47	18	the	the	DT
cord-026340-2nf97zvc	47	19	3′	3′	CD
cord-026340-2nf97zvc	47	20	end	end	NN
cord-026340-2nf97zvc	47	21	.	.	.
cord-026340-2nf97zvc	48	1	RNA	RNA	NNP
cord-026340-2nf97zvc	48	2	is	be	VBZ
cord-026340-2nf97zvc	48	3	positive	positive	JJ
cord-026340-2nf97zvc	48	4	and	and	CC
cord-026340-2nf97zvc	48	5	,	,	,
cord-026340-2nf97zvc	48	6	hence	hence	RB
cord-026340-2nf97zvc	48	7	,	,	,
cord-026340-2nf97zvc	48	8	can	can	MD
cord-026340-2nf97zvc	48	9	serve	serve	VB
cord-026340-2nf97zvc	48	10	as	as	IN
cord-026340-2nf97zvc	48	11	messenger	messenger	NN
cord-026340-2nf97zvc	48	12	RNA	RNA	NNP
cord-026340-2nf97zvc	48	13	(	(	-LRB-
cord-026340-2nf97zvc	48	14	mRNA	mRNA	NNP
cord-026340-2nf97zvc	48	15	)	)	-RRB-
cord-026340-2nf97zvc	48	16	,	,	,
cord-026340-2nf97zvc	48	17	allowing	allow	VBG
cord-026340-2nf97zvc	48	18	the	the	DT
cord-026340-2nf97zvc	48	19	translation	translation	NN
cord-026340-2nf97zvc	48	20	of	of	IN
cord-026340-2nf97zvc	48	21	replicase	replicase	NNP
cord-026340-2nf97zvc	48	22	/	/	SYM
cord-026340-2nf97zvc	48	23	transcriptase	transcriptase	NN
cord-026340-2nf97zvc	48	24	and	and	CC
cord-026340-2nf97zvc	48	25	structural	structural	JJ
cord-026340-2nf97zvc	48	26	proteins	protein	NNS
cord-026340-2nf97zvc	48	27	.	.	.
cord-026340-2nf97zvc	49	1	The	the	DT
cord-026340-2nf97zvc	49	2	replicase	replicase	NN
cord-026340-2nf97zvc	49	3	/	/	SYM
cord-026340-2nf97zvc	49	4	transcriptase	transcriptase	NN
cord-026340-2nf97zvc	49	5	is	be	VBZ
cord-026340-2nf97zvc	49	6	composed	compose	VBN
cord-026340-2nf97zvc	49	7	of	of	IN
cord-026340-2nf97zvc	49	8	two	two	CD
cord-026340-2nf97zvc	49	9	overlapping	overlap	VBG
cord-026340-2nf97zvc	49	10	open	open	JJ
cord-026340-2nf97zvc	49	11	reading	reading	NN
cord-026340-2nf97zvc	49	12	frames	frame	NNS
cord-026340-2nf97zvc	49	13	(	(	-LRB-
cord-026340-2nf97zvc	49	14	ORFs	ORFs	NNP
cord-026340-2nf97zvc	49	15	)	)	-RRB-
cord-026340-2nf97zvc	49	16	:	:	:
cord-026340-2nf97zvc	49	17	ORF1a	ORF1a	NNP
cord-026340-2nf97zvc	49	18	and	and	CC
cord-026340-2nf97zvc	49	19	ORF1b	ORF1b	NNP
cord-026340-2nf97zvc	49	20	which	which	WDT
cord-026340-2nf97zvc	49	21	encode	encode	VBP
cord-026340-2nf97zvc	49	22	16	16	CD
cord-026340-2nf97zvc	49	23	non	non	JJ
cord-026340-2nf97zvc	49	24	-	-	JJ
cord-026340-2nf97zvc	49	25	structural	structural	JJ
cord-026340-2nf97zvc	49	26	proteins	protein	NNS
cord-026340-2nf97zvc	49	27	and	and	CC
cord-026340-2nf97zvc	49	28	4	4	CD
cord-026340-2nf97zvc	49	29	classical	classical	JJ
cord-026340-2nf97zvc	49	30	structural	structural	JJ
cord-026340-2nf97zvc	49	31	proteins	protein	NNS
cord-026340-2nf97zvc	49	32	,	,	,
cord-026340-2nf97zvc	49	33	viz	viz	NN
cord-026340-2nf97zvc	49	34	.	.	.
cord-026340-2nf97zvc	50	1	(	(	-LRB-
cord-026340-2nf97zvc	50	2	i	i	NN
cord-026340-2nf97zvc	50	3	)	)	-RRB-
cord-026340-2nf97zvc	50	4	spike	spike	NN
cord-026340-2nf97zvc	50	5	protein	protein	NN
cord-026340-2nf97zvc	50	6	(	(	-LRB-
cord-026340-2nf97zvc	50	7	S	S	NNP
cord-026340-2nf97zvc	50	8	)	)	-RRB-
cord-026340-2nf97zvc	50	9	,	,	,
cord-026340-2nf97zvc	50	10	(	(	-LRB-
cord-026340-2nf97zvc	50	11	ii	ii	NN
cord-026340-2nf97zvc	50	12	)	)	-RRB-
cord-026340-2nf97zvc	50	13	envelope	envelope	NN
cord-026340-2nf97zvc	50	14	protein	protein	NN
cord-026340-2nf97zvc	50	15	(	(	-LRB-
cord-026340-2nf97zvc	50	16	E	E	NNP
cord-026340-2nf97zvc	50	17	)	)	-RRB-
cord-026340-2nf97zvc	50	18	,	,	,
cord-026340-2nf97zvc	50	19	(	(	-LRB-
cord-026340-2nf97zvc	50	20	iii	iii	NN
cord-026340-2nf97zvc	50	21	)	)	-RRB-
cord-026340-2nf97zvc	50	22	membrane	membrane	NN
cord-026340-2nf97zvc	50	23	protein	protein	NN
cord-026340-2nf97zvc	50	24	(	(	-LRB-
cord-026340-2nf97zvc	50	25	M	M	NNP
cord-026340-2nf97zvc	50	26	)	)	-RRB-
cord-026340-2nf97zvc	50	27	,	,	,
cord-026340-2nf97zvc	50	28	and	and	CC
cord-026340-2nf97zvc	50	29	(	(	-LRB-
cord-026340-2nf97zvc	50	30	iv	iv	LS
cord-026340-2nf97zvc	50	31	)	)	-RRB-
cord-026340-2nf97zvc	50	32	nucleocapsid	nucleocapsid	NNP
cord-026340-2nf97zvc	50	33	protein	protein	NNP
cord-026340-2nf97zvc	50	34	(	(	-LRB-
cord-026340-2nf97zvc	50	35	N	N	NNP
cord-026340-2nf97zvc	50	36	)	)	-RRB-
cord-026340-2nf97zvc	50	37	(	(	-LRB-
cord-026340-2nf97zvc	50	38	Lodish	Lodish	NNP
cord-026340-2nf97zvc	50	39	et	et	FW
cord-026340-2nf97zvc	50	40	al	al	NNP
cord-026340-2nf97zvc	50	41	.	.	.
cord-026340-2nf97zvc	50	42	2000	2000	CD
cord-026340-2nf97zvc	50	43	)	)	-RRB-
cord-026340-2nf97zvc	50	44	.	.	.
cord-026340-2nf97zvc	51	1	M	M	NNP
cord-026340-2nf97zvc	51	2	and	and	CC
cord-026340-2nf97zvc	51	3	E	e	NN
cord-026340-2nf97zvc	51	4	proteins	protein	NNS
cord-026340-2nf97zvc	51	5	are	be	VBP
cord-026340-2nf97zvc	51	6	involved	involve	VBN
cord-026340-2nf97zvc	51	7	in	in	IN
cord-026340-2nf97zvc	51	8	virus	virus	NN
cord-026340-2nf97zvc	51	9	assembly	assembly	NN
cord-026340-2nf97zvc	51	10	.	.	.
cord-026340-2nf97zvc	52	1	S	s	NN
cord-026340-2nf97zvc	52	2	protein	protein	NN
cord-026340-2nf97zvc	52	3	is	be	VBZ
cord-026340-2nf97zvc	52	4	leading	lead	VBG
cord-026340-2nf97zvc	52	5	mediator	mediator	NN
cord-026340-2nf97zvc	52	6	of	of	IN
cord-026340-2nf97zvc	52	7	viral	viral	JJ
cord-026340-2nf97zvc	52	8	entry	entry	NN
cord-026340-2nf97zvc	52	9	and	and	CC
cord-026340-2nf97zvc	52	10	critical	critical	JJ
cord-026340-2nf97zvc	52	11	player	player	NN
cord-026340-2nf97zvc	52	12	in	in	IN
cord-026340-2nf97zvc	52	13	determining	determine	VBG
cord-026340-2nf97zvc	52	14	host	host	NN
cord-026340-2nf97zvc	52	15	range	range	NN
cord-026340-2nf97zvc	52	16	.	.	.
cord-026340-2nf97zvc	53	1	Modification	modification	NN
cord-026340-2nf97zvc	53	2	in	in	IN
cord-026340-2nf97zvc	53	3	S	S	NNP
cord-026340-2nf97zvc	53	4	protein	protein	NN
cord-026340-2nf97zvc	53	5	alters	alter	VBZ
cord-026340-2nf97zvc	53	6	cell	cell	NN
cord-026340-2nf97zvc	53	7	and	and	CC
cord-026340-2nf97zvc	53	8	tissue	tissue	NN
cord-026340-2nf97zvc	53	9	tropism	tropism	NN
cord-026340-2nf97zvc	53	10	,	,	,
cord-026340-2nf97zvc	53	11	association	association	NN
cord-026340-2nf97zvc	53	12	with	with	IN
cord-026340-2nf97zvc	53	13	other	other	JJ
cord-026340-2nf97zvc	53	14	viral	viral	JJ
cord-026340-2nf97zvc	53	15	and	and	CC
cord-026340-2nf97zvc	53	16	host	host	NN
cord-026340-2nf97zvc	53	17	factors	factor	NNS
cord-026340-2nf97zvc	53	18	and	and	CC
cord-026340-2nf97zvc	53	19	changes	change	NNS
cord-026340-2nf97zvc	53	20	in	in	IN
cord-026340-2nf97zvc	53	21	host	host	NN
cord-026340-2nf97zvc	53	22	pathogenicity	pathogenicity	NN
cord-026340-2nf97zvc	53	23	(	(	-LRB-
cord-026340-2nf97zvc	53	24	Belouzard	Belouzard	NNP
cord-026340-2nf97zvc	53	25	et	et	NNP
cord-026340-2nf97zvc	53	26	al	al	NNP
cord-026340-2nf97zvc	53	27	.	.	NNP
cord-026340-2nf97zvc	53	28	2012	2012	CD
cord-026340-2nf97zvc	53	29	)	)	-RRB-
cord-026340-2nf97zvc	53	30	.	.	.
cord-026340-2nf97zvc	54	1	CoVs	CoVs	NNP
cord-026340-2nf97zvc	54	2	mainly	mainly	RB
cord-026340-2nf97zvc	54	3	cause	cause	VBP
cord-026340-2nf97zvc	54	4	respiratory	respiratory	JJ
cord-026340-2nf97zvc	54	5	and	and	CC
cord-026340-2nf97zvc	54	6	intestinal	intestinal	JJ
cord-026340-2nf97zvc	54	7	infections	infection	NNS
cord-026340-2nf97zvc	54	8	with	with	IN
cord-026340-2nf97zvc	54	9	an	an	DT
cord-026340-2nf97zvc	54	10	array	array	NN
cord-026340-2nf97zvc	54	11	of	of	IN
cord-026340-2nf97zvc	54	12	clinical	clinical	JJ
cord-026340-2nf97zvc	54	13	manifestations	manifestation	NNS
cord-026340-2nf97zvc	54	14	.	.	.
cord-026340-2nf97zvc	55	1	So	so	RB
cord-026340-2nf97zvc	55	2	far	far	RB
cord-026340-2nf97zvc	55	3	,	,	,
cord-026340-2nf97zvc	55	4	7	7	CD
cord-026340-2nf97zvc	55	5	CoVs	CoVs	NNP
cord-026340-2nf97zvc	55	6	have	have	VBP
cord-026340-2nf97zvc	55	7	been	be	VBN
cord-026340-2nf97zvc	55	8	identified	identify	VBN
cord-026340-2nf97zvc	55	9	that	that	IN
cord-026340-2nf97zvc	55	10	produce	produce	VBP
cord-026340-2nf97zvc	55	11	infections	infection	NNS
cord-026340-2nf97zvc	55	12	in	in	IN
cord-026340-2nf97zvc	55	13	humans	human	NNS
cord-026340-2nf97zvc	55	14	.	.	.
cord-026340-2nf97zvc	56	1	These	these	DT
cord-026340-2nf97zvc	56	2	are	be	VBP
cord-026340-2nf97zvc	56	3	the	the	DT
cord-026340-2nf97zvc	56	4	α	α	NN
cord-026340-2nf97zvc	56	5	-	-	HYPH
cord-026340-2nf97zvc	56	6	type	type	NN
cord-026340-2nf97zvc	56	7	HCoV-229E	HCoV-229E	NNP
cord-026340-2nf97zvc	56	8	and	and	CC
cord-026340-2nf97zvc	56	9	HCoV	HCoV	NNP
cord-026340-2nf97zvc	56	10	-	-	HYPH
cord-026340-2nf97zvc	56	11	NL63	NL63	NNP
cord-026340-2nf97zvc	56	12	;	;	:
cord-026340-2nf97zvc	56	13	the	the	DT
cord-026340-2nf97zvc	56	14	β	β	NN
cord-026340-2nf97zvc	56	15	-	-	HYPH
cord-026340-2nf97zvc	56	16	type	type	NN
cord-026340-2nf97zvc	56	17	HCoV	HCoV	NNP
cord-026340-2nf97zvc	56	18	-	-	HYPH
cord-026340-2nf97zvc	56	19	HKU1	HKU1	NNP
cord-026340-2nf97zvc	56	20	,	,	,
cord-026340-2nf97zvc	56	21	SARS	SARS	NNP
cord-026340-2nf97zvc	56	22	-	-	HYPH
cord-026340-2nf97zvc	56	23	CoV	CoV	NNP
cord-026340-2nf97zvc	56	24	,	,	,
cord-026340-2nf97zvc	56	25	MERS	MERS	NNP
cord-026340-2nf97zvc	56	26	-	-	HYPH
cord-026340-2nf97zvc	56	27	CoV	CoV	NNP
cord-026340-2nf97zvc	56	28	,	,	,
cord-026340-2nf97zvc	56	29	and	and	CC
cord-026340-2nf97zvc	56	30	HCoV	HCoV	NNP
cord-026340-2nf97zvc	56	31	-	-	HYPH
cord-026340-2nf97zvc	56	32	OC43	OC43	NNP
cord-026340-2nf97zvc	56	33	;	;	:
cord-026340-2nf97zvc	56	34	and	and	CC
cord-026340-2nf97zvc	56	35	2019-nCoV	2019-ncov	LS
cord-026340-2nf97zvc	56	36	(	(	-LRB-
cord-026340-2nf97zvc	56	37	that	that	WDT
cord-026340-2nf97zvc	56	38	caused	cause	VBD
cord-026340-2nf97zvc	56	39	the	the	DT
cord-026340-2nf97zvc	56	40	present	present	JJ
cord-026340-2nf97zvc	56	41	pandemic	pandemic	NN
cord-026340-2nf97zvc	56	42	)	)	-RRB-
cord-026340-2nf97zvc	56	43	.	.	.
cord-026340-2nf97zvc	57	1	HCoV-229E	HCoV-229E	NNP
cord-026340-2nf97zvc	57	2	,	,	,
cord-026340-2nf97zvc	57	3	HCoV	HCoV	NNP
cord-026340-2nf97zvc	57	4	-	-	HYPH
cord-026340-2nf97zvc	57	5	OC43	OC43	NNP
cord-026340-2nf97zvc	57	6	,	,	,
cord-026340-2nf97zvc	57	7	HCoV	HCoV	NNP
cord-026340-2nf97zvc	57	8	-	-	HYPH
cord-026340-2nf97zvc	57	9	NL63	NL63	NNP
cord-026340-2nf97zvc	57	10	,	,	,
cord-026340-2nf97zvc	57	11	and	and	CC
cord-026340-2nf97zvc	57	12	HCoV	HCoV	NNP
cord-026340-2nf97zvc	57	13	-	-	HYPH
cord-026340-2nf97zvc	57	14	HKU	HKU	NNP
cord-026340-2nf97zvc	57	15	were	be	VBD
cord-026340-2nf97zvc	57	16	mildly	mildly	RB
cord-026340-2nf97zvc	57	17	pathogenic	pathogenic	JJ
cord-026340-2nf97zvc	57	18	;	;	:
cord-026340-2nf97zvc	57	19	while	while	IN
cord-026340-2nf97zvc	57	20	SARS	SARS	NNP
cord-026340-2nf97zvc	57	21	-	-	HYPH
cord-026340-2nf97zvc	57	22	CoV	CoV	NNP
cord-026340-2nf97zvc	57	23	or	or	CC
cord-026340-2nf97zvc	57	24	Severe	severe	JJ
cord-026340-2nf97zvc	57	25	Acute	Acute	NNP
cord-026340-2nf97zvc	57	26	Respiratory	Respiratory	NNP
cord-026340-2nf97zvc	57	27	Syndrome	Syndrome	NNP
cord-026340-2nf97zvc	57	28	CoV	cov	NN
cord-026340-2nf97zvc	57	29	,	,	,
cord-026340-2nf97zvc	57	30	and	and	CC
cord-026340-2nf97zvc	57	31	MERS	MERS	NNP
cord-026340-2nf97zvc	57	32	-	-	HYPH
cord-026340-2nf97zvc	57	33	CoV	CoV	NNP
cord-026340-2nf97zvc	57	34	or	or	CC
cord-026340-2nf97zvc	57	35	Middle	Middle	NNP
cord-026340-2nf97zvc	57	36	East	East	NNP
cord-026340-2nf97zvc	57	37	respiratory	respiratory	JJ
cord-026340-2nf97zvc	57	38	syndrome	syndrome	NN
cord-026340-2nf97zvc	57	39	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	57	40	were	be	VBD
cord-026340-2nf97zvc	57	41	highly	highly	RB
cord-026340-2nf97zvc	57	42	pathogenic	pathogenic	JJ
cord-026340-2nf97zvc	57	43	.	.	.
cord-026340-2nf97zvc	58	1	The	the	DT
cord-026340-2nf97zvc	58	2	highly	highly	RB
cord-026340-2nf97zvc	58	3	pathogenic	pathogenic	JJ
cord-026340-2nf97zvc	58	4	CoVs	cov	NNS
cord-026340-2nf97zvc	58	5	infect	infect	VBP
cord-026340-2nf97zvc	58	6	the	the	DT
cord-026340-2nf97zvc	58	7	lower	low	JJR
cord-026340-2nf97zvc	58	8	respiratory	respiratory	JJ
cord-026340-2nf97zvc	58	9	tract	tract	NN
cord-026340-2nf97zvc	58	10	causing	cause	VBG
cord-026340-2nf97zvc	58	11	fatal	fatal	JJ
cord-026340-2nf97zvc	58	12	acute	acute	JJ
cord-026340-2nf97zvc	58	13	lung	lung	NN
cord-026340-2nf97zvc	58	14	injury	injury	NN
cord-026340-2nf97zvc	58	15	(	(	-LRB-
cord-026340-2nf97zvc	58	16	ALI	ALI	NNP
cord-026340-2nf97zvc	58	17	)	)	-RRB-
cord-026340-2nf97zvc	58	18	and	and	CC
cord-026340-2nf97zvc	58	19	acute	acute	JJ
cord-026340-2nf97zvc	58	20	respiratory	respiratory	JJ
cord-026340-2nf97zvc	58	21	disease	disease	NN
cord-026340-2nf97zvc	58	22	syndrome	syndrome	NN
cord-026340-2nf97zvc	58	23	(	(	-LRB-
cord-026340-2nf97zvc	58	24	ARDS	ARDS	NNP
cord-026340-2nf97zvc	58	25	)	)	-RRB-
cord-026340-2nf97zvc	58	26	.	.	.
cord-026340-2nf97zvc	59	1	We	-PRON-	PRP
cord-026340-2nf97zvc	59	2	are	be	VBP
cord-026340-2nf97zvc	59	3	yet	yet	RB
cord-026340-2nf97zvc	59	4	to	to	TO
cord-026340-2nf97zvc	59	5	determine	determine	VB
cord-026340-2nf97zvc	59	6	the	the	DT
cord-026340-2nf97zvc	59	7	severity	severity	NN
cord-026340-2nf97zvc	59	8	of	of	IN
cord-026340-2nf97zvc	59	9	SARS	SARS	NNP
cord-026340-2nf97zvc	59	10	-	-	HYPH
cord-026340-2nf97zvc	59	11	CoV2	CoV2	NNP
cord-026340-2nf97zvc	60	1	(	(	-LRB-
cord-026340-2nf97zvc	60	2	Abd	Abd	NNP
cord-026340-2nf97zvc	60	3	El	El	NNP
cord-026340-2nf97zvc	60	4	-	-	HYPH
cord-026340-2nf97zvc	60	5	Aziz	Aziz	NNP
cord-026340-2nf97zvc	60	6	and	and	CC
cord-026340-2nf97zvc	60	7	Stockand	Stockand	NNP
cord-026340-2nf97zvc	60	8	2020	2020	CD
cord-026340-2nf97zvc	60	9	)	)	-RRB-
cord-026340-2nf97zvc	60	10	.	.	.
cord-026340-2nf97zvc	61	1	What	what	WP
cord-026340-2nf97zvc	61	2	is	be	VBZ
cord-026340-2nf97zvc	61	3	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	61	4	?	?	.
cord-026340-2nf97zvc	62	1	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	62	2	is	be	VBZ
cord-026340-2nf97zvc	62	3	a	a	DT
cord-026340-2nf97zvc	62	4	peculiar	peculiar	JJ
cord-026340-2nf97zvc	62	5	form	form	NN
cord-026340-2nf97zvc	62	6	of	of	IN
cord-026340-2nf97zvc	62	7	respiratory	respiratory	JJ
cord-026340-2nf97zvc	62	8	disorder	disorder	NN
cord-026340-2nf97zvc	62	9	that	that	WDT
cord-026340-2nf97zvc	62	10	emerged	emerge	VBD
cord-026340-2nf97zvc	62	11	in	in	IN
cord-026340-2nf97zvc	62	12	2019	2019	CD
cord-026340-2nf97zvc	62	13	in	in	IN
cord-026340-2nf97zvc	62	14	a	a	DT
cord-026340-2nf97zvc	62	15	business	business	NN
cord-026340-2nf97zvc	62	16	hub	hub	NN
cord-026340-2nf97zvc	62	17	called	call	VBN
cord-026340-2nf97zvc	62	18	Wuhan	Wuhan	NNP
cord-026340-2nf97zvc	62	19	,	,	,
cord-026340-2nf97zvc	62	20	which	which	WDT
cord-026340-2nf97zvc	62	21	is	be	VBZ
cord-026340-2nf97zvc	62	22	located	locate	VBN
cord-026340-2nf97zvc	62	23	in	in	IN
cord-026340-2nf97zvc	62	24	the	the	DT
cord-026340-2nf97zvc	62	25	Hubei	Hubei	NNP
cord-026340-2nf97zvc	62	26	Province	Province	NNP
cord-026340-2nf97zvc	62	27	of	of	IN
cord-026340-2nf97zvc	62	28	China	China	NNP
cord-026340-2nf97zvc	62	29	.	.	.
cord-026340-2nf97zvc	63	1	Initially	initially	RB
cord-026340-2nf97zvc	63	2	,	,	,
cord-026340-2nf97zvc	63	3	China	China	NNP
cord-026340-2nf97zvc	63	4	described	describe	VBD
cord-026340-2nf97zvc	63	5	the	the	DT
cord-026340-2nf97zvc	63	6	disease	disease	NN
cord-026340-2nf97zvc	63	7	as	as	IN
cord-026340-2nf97zvc	63	8	'	'	``
cord-026340-2nf97zvc	63	9	atypical	atypical	JJ
cord-026340-2nf97zvc	63	10	'	'	''
cord-026340-2nf97zvc	63	11	pneumonia	pneumonia	NN
cord-026340-2nf97zvc	63	12	and	and	CC
cord-026340-2nf97zvc	63	13	then	then	RB
cord-026340-2nf97zvc	63	14	declared	declare	VBD
cord-026340-2nf97zvc	63	15	the	the	DT
cord-026340-2nf97zvc	63	16	causative	causative	JJ
cord-026340-2nf97zvc	63	17	agent	agent	NN
cord-026340-2nf97zvc	63	18	to	to	TO
cord-026340-2nf97zvc	63	19	be	be	VB
cord-026340-2nf97zvc	63	20	a	a	DT
cord-026340-2nf97zvc	63	21	corona	corona	NN
cord-026340-2nf97zvc	63	22	virus	virus	NN
cord-026340-2nf97zvc	63	23	(	(	-LRB-
cord-026340-2nf97zvc	63	24	CoV	CoV	NNP
cord-026340-2nf97zvc	63	25	)	)	-RRB-
cord-026340-2nf97zvc	63	26	.	.	.
cord-026340-2nf97zvc	64	1	The	the	DT
cord-026340-2nf97zvc	64	2	Corona	Corona	NNP
cord-026340-2nf97zvc	64	3	Study	Study	NNP
cord-026340-2nf97zvc	64	4	Group	Group	NNP
cord-026340-2nf97zvc	64	5	(	(	-LRB-
cord-026340-2nf97zvc	64	6	CSG	CSG	NNP
cord-026340-2nf97zvc	64	7	)	)	-RRB-
cord-026340-2nf97zvc	64	8	of	of	IN
cord-026340-2nf97zvc	64	9	the	the	DT
cord-026340-2nf97zvc	64	10	International	International	NNP
cord-026340-2nf97zvc	64	11	Committee	Committee	NNP
cord-026340-2nf97zvc	64	12	on	on	IN
cord-026340-2nf97zvc	64	13	Taxonomy	Taxonomy	NNP
cord-026340-2nf97zvc	64	14	of	of	IN
cord-026340-2nf97zvc	64	15	Viruses	Viruses	NNPS
cord-026340-2nf97zvc	64	16	(	(	-LRB-
cord-026340-2nf97zvc	64	17	ICTV	ICTV	NNP
cord-026340-2nf97zvc	64	18	)	)	-RRB-
cord-026340-2nf97zvc	64	19	after	after	IN
cord-026340-2nf97zvc	64	20	assessing	assess	VBG
cord-026340-2nf97zvc	64	21	the	the	DT
cord-026340-2nf97zvc	64	22	etiological	etiological	JJ
cord-026340-2nf97zvc	64	23	agent	agent	NN
cord-026340-2nf97zvc	64	24	named	name	VBN
cord-026340-2nf97zvc	64	25	it	-PRON-	PRP
cord-026340-2nf97zvc	64	26	SARS	SARS	NNP
cord-026340-2nf97zvc	64	27	-	-	HYPH
cord-026340-2nf97zvc	64	28	CoV2	CoV2	NNP
cord-026340-2nf97zvc	64	29	(	(	-LRB-
cord-026340-2nf97zvc	64	30	Severe	severe	JJ
cord-026340-2nf97zvc	64	31	Acute	acute	JJ
cord-026340-2nf97zvc	64	32	Respiratory	Respiratory	NNP
cord-026340-2nf97zvc	64	33	Syndrome	Syndrome	NNP
cord-026340-2nf97zvc	64	34	Corona	Corona	NNP
cord-026340-2nf97zvc	64	35	Virus2	Virus2	NNP
cord-026340-2nf97zvc	64	36	)	)	-RRB-
cord-026340-2nf97zvc	64	37	and	and	CC
cord-026340-2nf97zvc	64	38	the	the	DT
cord-026340-2nf97zvc	64	39	disease	disease	NN
cord-026340-2nf97zvc	64	40	outbreak	outbreak	NN
cord-026340-2nf97zvc	64	41	as	as	IN
cord-026340-2nf97zvc	64	42	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	65	1	(	(	-LRB-
cord-026340-2nf97zvc	65	2	Corona	Corona	NNP
cord-026340-2nf97zvc	65	3	Virus	Virus	NNP
cord-026340-2nf97zvc	65	4	Disease	Disease	NNP
cord-026340-2nf97zvc	65	5	-	-	HYPH
cord-026340-2nf97zvc	65	6	Year	Year	NNP
cord-026340-2nf97zvc	65	7	of	of	IN
cord-026340-2nf97zvc	65	8	Identification	Identification	NNP
cord-026340-2nf97zvc	65	9	)	)	-RRB-
cord-026340-2nf97zvc	65	10	.	.	.
cord-026340-2nf97zvc	66	1	The	the	DT
cord-026340-2nf97zvc	66	2	disease	disease	NN
cord-026340-2nf97zvc	66	3	rapidly	rapidly	RB
cord-026340-2nf97zvc	66	4	spread	spread	VBD
cord-026340-2nf97zvc	66	5	to	to	IN
cord-026340-2nf97zvc	66	6	more	more	JJR
cord-026340-2nf97zvc	66	7	than	than	IN
cord-026340-2nf97zvc	66	8	210	210	CD
cord-026340-2nf97zvc	66	9	countries	country	NNS
cord-026340-2nf97zvc	66	10	mostly	mostly	RB
cord-026340-2nf97zvc	66	11	via	via	IN
cord-026340-2nf97zvc	66	12	people	people	NNS
cord-026340-2nf97zvc	66	13	with	with	IN
cord-026340-2nf97zvc	66	14	a	a	DT
cord-026340-2nf97zvc	66	15	travel	travel	NN
cord-026340-2nf97zvc	66	16	history	history	NN
cord-026340-2nf97zvc	66	17	.	.	.
cord-026340-2nf97zvc	67	1	As	as	IN
cord-026340-2nf97zvc	67	2	on	on	IN
cord-026340-2nf97zvc	67	3	26th	26th	JJ
cord-026340-2nf97zvc	67	4	April	April	NNP
cord-026340-2nf97zvc	67	5	2020	2020	CD
cord-026340-2nf97zvc	67	6	approximately	approximately	RB
cord-026340-2nf97zvc	67	7	2,80,4796	2,80,4796	CD
cord-026340-2nf97zvc	67	8	deaths	death	NNS
cord-026340-2nf97zvc	67	9	were	be	VBD
cord-026340-2nf97zvc	67	10	reported	report	VBN
cord-026340-2nf97zvc	67	11	worldwide	worldwide	RB
cord-026340-2nf97zvc	67	12	owing	owe	VBG
cord-026340-2nf97zvc	67	13	to	to	IN
cord-026340-2nf97zvc	67	14	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	67	15	(	(	-LRB-
cord-026340-2nf97zvc	67	16	WHO	who	WP
cord-026340-2nf97zvc	67	17	2020b	2020b	CD
cord-026340-2nf97zvc	67	18	)	)	-RRB-
cord-026340-2nf97zvc	67	19	.	.	.
cord-026340-2nf97zvc	68	1	Characterization	characterization	NN
cord-026340-2nf97zvc	68	2	of	of	IN
cord-026340-2nf97zvc	68	3	SARS	SARS	NNP
cord-026340-2nf97zvc	68	4	-	-	HYPH
cord-026340-2nf97zvc	68	5	CoV2	CoV2	NNP
cord-026340-2nf97zvc	68	6	is	be	VBZ
cord-026340-2nf97zvc	68	7	under	under	IN
cord-026340-2nf97zvc	68	8	progress	progress	NN
cord-026340-2nf97zvc	68	9	.	.	.
cord-026340-2nf97zvc	69	1	How	how	WRB
cord-026340-2nf97zvc	69	2	did	do	VBD
cord-026340-2nf97zvc	69	3	COVID-19	covid-19	VB
cord-026340-2nf97zvc	69	4	originate	originate	VB
cord-026340-2nf97zvc	69	5	?	?	.
cord-026340-2nf97zvc	70	1	The	the	DT
cord-026340-2nf97zvc	70	2	source	source	NN
cord-026340-2nf97zvc	70	3	of	of	IN
cord-026340-2nf97zvc	70	4	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	70	5	outbreak	outbreak	NN
cord-026340-2nf97zvc	70	6	is	be	VBZ
cord-026340-2nf97zvc	70	7	yet	yet	RB
cord-026340-2nf97zvc	70	8	to	to	TO
cord-026340-2nf97zvc	70	9	be	be	VB
cord-026340-2nf97zvc	70	10	determined	determine	VBN
cord-026340-2nf97zvc	70	11	.	.	.
cord-026340-2nf97zvc	71	1	Although	although	IN
cord-026340-2nf97zvc	71	2	some	some	DT
cord-026340-2nf97zvc	71	3	preliminary	preliminary	JJ
cord-026340-2nf97zvc	71	4	investigations	investigation	NNS
cord-026340-2nf97zvc	71	5	in	in	IN
cord-026340-2nf97zvc	71	6	China	China	NNP
cord-026340-2nf97zvc	71	7	identified	identify	VBD
cord-026340-2nf97zvc	71	8	samples	sample	NNS
cord-026340-2nf97zvc	71	9	in	in	IN
cord-026340-2nf97zvc	71	10	the	the	DT
cord-026340-2nf97zvc	71	11	Huanan	Huanan	NNP
cord-026340-2nf97zvc	71	12	Seafood	Seafood	NNP
cord-026340-2nf97zvc	71	13	Wholesale	Wholesale	NNP
cord-026340-2nf97zvc	71	14	Market	Market	NNP
cord-026340-2nf97zvc	71	15	of	of	IN
cord-026340-2nf97zvc	71	16	Wuhan	Wuhan	NNP
cord-026340-2nf97zvc	71	17	city	city	NN
cord-026340-2nf97zvc	71	18	to	to	TO
cord-026340-2nf97zvc	71	19	be	be	VB
cord-026340-2nf97zvc	71	20	positive	positive	JJ
cord-026340-2nf97zvc	71	21	for	for	IN
cord-026340-2nf97zvc	71	22	SARS	SARS	NNP
cord-026340-2nf97zvc	71	23	-	-	HYPH
cord-026340-2nf97zvc	71	24	CoV2	CoV2	NNP
cord-026340-2nf97zvc	71	25	,	,	,
cord-026340-2nf97zvc	71	26	the	the	DT
cord-026340-2nf97zvc	71	27	zoonotic	zoonotic	JJ
cord-026340-2nf97zvc	71	28	source	source	NN
cord-026340-2nf97zvc	71	29	of	of	IN
cord-026340-2nf97zvc	71	30	the	the	DT
cord-026340-2nf97zvc	71	31	outbreak	outbreak	NN
cord-026340-2nf97zvc	71	32	is	be	VBZ
cord-026340-2nf97zvc	71	33	still	still	RB
cord-026340-2nf97zvc	71	34	ambiguous	ambiguous	JJ
cord-026340-2nf97zvc	71	35	.	.	.
cord-026340-2nf97zvc	72	1	All	all	RB
cord-026340-2nf97zvc	72	2	throughout	throughout	IN
cord-026340-2nf97zvc	72	3	the	the	DT
cord-026340-2nf97zvc	72	4	pandemic	pandemic	NN
cord-026340-2nf97zvc	72	5	,	,	,
cord-026340-2nf97zvc	72	6	it	-PRON-	PRP
cord-026340-2nf97zvc	72	7	was	be	VBD
cord-026340-2nf97zvc	72	8	argued	argue	VBN
cord-026340-2nf97zvc	72	9	by	by	IN
cord-026340-2nf97zvc	72	10	many	many	JJ
cord-026340-2nf97zvc	72	11	researchers	researcher	NNS
cord-026340-2nf97zvc	72	12	that	that	IN
cord-026340-2nf97zvc	72	13	bats	bat	NNS
cord-026340-2nf97zvc	72	14	which	which	WDT
cord-026340-2nf97zvc	72	15	harbor	harbor	VBP
cord-026340-2nf97zvc	72	16	a	a	DT
cord-026340-2nf97zvc	72	17	lot	lot	NN
cord-026340-2nf97zvc	72	18	of	of	IN
cord-026340-2nf97zvc	72	19	viruses	virus	NNS
cord-026340-2nf97zvc	72	20	(	(	-LRB-
cord-026340-2nf97zvc	72	21	but	but	CC
cord-026340-2nf97zvc	72	22	remain	remain	VBP
cord-026340-2nf97zvc	72	23	unaffected	unaffected	JJ
cord-026340-2nf97zvc	72	24	by	by	IN
cord-026340-2nf97zvc	72	25	these	these	DT
cord-026340-2nf97zvc	72	26	)	)	-RRB-
cord-026340-2nf97zvc	72	27	are	be	VBP
cord-026340-2nf97zvc	72	28	a	a	DT
cord-026340-2nf97zvc	72	29	reason	reason	NN
cord-026340-2nf97zvc	72	30	for	for	IN
cord-026340-2nf97zvc	72	31	the	the	DT
cord-026340-2nf97zvc	72	32	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	72	33	outbreak	outbreak	NN
cord-026340-2nf97zvc	72	34	.	.	.
cord-026340-2nf97zvc	73	1	This	this	DT
cord-026340-2nf97zvc	73	2	was	be	VBD
cord-026340-2nf97zvc	73	3	because	because	IN
cord-026340-2nf97zvc	73	4	some	some	DT
cord-026340-2nf97zvc	73	5	bats	bat	NNS
cord-026340-2nf97zvc	73	6	called	call	VBD
cord-026340-2nf97zvc	73	7	'	'	''
cord-026340-2nf97zvc	73	8	intermediate	intermediate	JJ
cord-026340-2nf97zvc	73	9	horseshoe	horseshoe	NN
cord-026340-2nf97zvc	73	10	bats	bat	NNS
cord-026340-2nf97zvc	73	11	'	'	POS
cord-026340-2nf97zvc	73	12	(	(	-LRB-
cord-026340-2nf97zvc	73	13	Rhinolophus	Rhinolophus	NNP
cord-026340-2nf97zvc	73	14	affinis	affinis	NN
cord-026340-2nf97zvc	73	15	)	)	-RRB-
cord-026340-2nf97zvc	73	16	of	of	IN
cord-026340-2nf97zvc	73	17	Rhinolophidae	Rhinolophidae	NNP
cord-026340-2nf97zvc	73	18	family	family	NN
cord-026340-2nf97zvc	73	19	(	(	-LRB-
cord-026340-2nf97zvc	73	20	widespread	widespread	JJ
cord-026340-2nf97zvc	73	21	in	in	IN
cord-026340-2nf97zvc	73	22	central	central	JJ
cord-026340-2nf97zvc	73	23	China	China	NNP
cord-026340-2nf97zvc	73	24	,	,	,
cord-026340-2nf97zvc	73	25	Southeast	Southeast	NNP
cord-026340-2nf97zvc	73	26	Asia	Asia	NNP
cord-026340-2nf97zvc	73	27	and	and	CC
cord-026340-2nf97zvc	73	28	Indian	indian	JJ
cord-026340-2nf97zvc	73	29	subcontinent	subcontinent	NN
cord-026340-2nf97zvc	73	30	)	)	-RRB-
cord-026340-2nf97zvc	73	31	carry	carry	VBP
cord-026340-2nf97zvc	73	32	bat	bat	NN
cord-026340-2nf97zvc	73	33	corona	corona	NN
cord-026340-2nf97zvc	73	34	viruses	virus	NNS
cord-026340-2nf97zvc	73	35	called	call	VBN
cord-026340-2nf97zvc	73	36	BatCoV	BatCoV	NNP
cord-026340-2nf97zvc	73	37	RaTG13	RaTG13	NNP
cord-026340-2nf97zvc	74	1	(	(	-LRB-
cord-026340-2nf97zvc	74	2	popular	popular	JJ
cord-026340-2nf97zvc	74	3	in	in	IN
cord-026340-2nf97zvc	74	4	Yunnan	Yunnan	NNP
cord-026340-2nf97zvc	74	5	Province	Province	NNP
cord-026340-2nf97zvc	74	6	)	)	-RRB-
cord-026340-2nf97zvc	74	7	with	with	IN
cord-026340-2nf97zvc	74	8	96	96	CD
cord-026340-2nf97zvc	74	9	%	%	NN
cord-026340-2nf97zvc	74	10	whole	whole	JJ
cord-026340-2nf97zvc	74	11	genome	genome	NN
cord-026340-2nf97zvc	74	12	similarity	similarity	NN
cord-026340-2nf97zvc	74	13	with	with	IN
cord-026340-2nf97zvc	74	14	SARS	SARS	NNP
cord-026340-2nf97zvc	74	15	-	-	HYPH
cord-026340-2nf97zvc	74	16	CoV2	CoV2	NNP
cord-026340-2nf97zvc	74	17	(	(	-LRB-
cord-026340-2nf97zvc	74	18	Calisher	Calisher	NNP
cord-026340-2nf97zvc	74	19	et	et	NNP
cord-026340-2nf97zvc	74	20	al	al	NNP
cord-026340-2nf97zvc	74	21	.	.	.
cord-026340-2nf97zvc	74	22	2006	2006	CD
cord-026340-2nf97zvc	74	23	;	;	:
cord-026340-2nf97zvc	74	24	Zhang	Zhang	NNP
cord-026340-2nf97zvc	74	25	et	et	NNP
cord-026340-2nf97zvc	74	26	al	al	NNP
cord-026340-2nf97zvc	74	27	.	.	NNP
cord-026340-2nf97zvc	74	28	2020	2020	CD
cord-026340-2nf97zvc	74	29	)	)	-RRB-
cord-026340-2nf97zvc	74	30	.	.	.
cord-026340-2nf97zvc	75	1	However	however	RB
cord-026340-2nf97zvc	75	2	,	,	,
cord-026340-2nf97zvc	75	3	direct	direct	JJ
cord-026340-2nf97zvc	75	4	transmission	transmission	NN
cord-026340-2nf97zvc	75	5	of	of	IN
cord-026340-2nf97zvc	75	6	SARS	SARS	NNP
cord-026340-2nf97zvc	75	7	-	-	HYPH
cord-026340-2nf97zvc	75	8	CoV2	CoV2	NNS
cord-026340-2nf97zvc	75	9	from	from	IN
cord-026340-2nf97zvc	75	10	these	these	DT
cord-026340-2nf97zvc	75	11	bats	bat	NNS
cord-026340-2nf97zvc	75	12	was	be	VBD
cord-026340-2nf97zvc	75	13	not	not	RB
cord-026340-2nf97zvc	75	14	considered	consider	VBN
cord-026340-2nf97zvc	75	15	as	as	IN
cord-026340-2nf97zvc	75	16	evidences	evidence	NNS
cord-026340-2nf97zvc	75	17	from	from	IN
cord-026340-2nf97zvc	75	18	recent	recent	JJ
cord-026340-2nf97zvc	75	19	epidemics	epidemic	NNS
cord-026340-2nf97zvc	75	20	demonstrate	demonstrate	VBP
cord-026340-2nf97zvc	75	21	that	that	IN
cord-026340-2nf97zvc	75	22	efficient	efficient	JJ
cord-026340-2nf97zvc	75	23	human	human	NN
cord-026340-2nf97zvc	75	24	-	-	HYPH
cord-026340-2nf97zvc	75	25	to	to	IN
cord-026340-2nf97zvc	75	26	-	-	HYPH
cord-026340-2nf97zvc	75	27	human	human	JJ
cord-026340-2nf97zvc	75	28	transmissibility	transmissibility	NN
cord-026340-2nf97zvc	75	29	while	while	IN
cord-026340-2nf97zvc	75	30	retaining	retain	VBG
cord-026340-2nf97zvc	75	31	high	high	JJ
cord-026340-2nf97zvc	75	32	human	human	JJ
cord-026340-2nf97zvc	75	33	pathogenicity	pathogenicity	NN
cord-026340-2nf97zvc	75	34	is	be	VBZ
cord-026340-2nf97zvc	75	35	possible	possible	JJ
cord-026340-2nf97zvc	75	36	only	only	RB
cord-026340-2nf97zvc	75	37	with	with	IN
cord-026340-2nf97zvc	75	38	involvement	involvement	NN
cord-026340-2nf97zvc	75	39	of	of	IN
cord-026340-2nf97zvc	75	40	an	an	DT
cord-026340-2nf97zvc	75	41	intermediate	intermediate	JJ
cord-026340-2nf97zvc	75	42	host	host	NN
cord-026340-2nf97zvc	75	43	.	.	.
cord-026340-2nf97zvc	76	1	According	accord	VBG
cord-026340-2nf97zvc	76	2	to	to	IN
cord-026340-2nf97zvc	76	3	the	the	DT
cord-026340-2nf97zvc	76	4	current	current	JJ
cord-026340-2nf97zvc	76	5	evidence	evidence	NN
cord-026340-2nf97zvc	76	6	,	,	,
cord-026340-2nf97zvc	76	7	virus	virus	NN
cord-026340-2nf97zvc	76	8	isolated	isolate	VBN
cord-026340-2nf97zvc	76	9	from	from	IN
cord-026340-2nf97zvc	76	10	Malayan	malayan	JJ
cord-026340-2nf97zvc	76	11	Pangolins	Pangolins	NNPS
cord-026340-2nf97zvc	76	12	(	(	-LRB-
cord-026340-2nf97zvc	76	13	Manis	Manis	NNP
cord-026340-2nf97zvc	76	14	javanica	javanica	NNS
cord-026340-2nf97zvc	76	15	)	)	-RRB-
cord-026340-2nf97zvc	76	16	celled	celled	JJ
cord-026340-2nf97zvc	76	17	Pangolin	Pangolin	NNP
cord-026340-2nf97zvc	76	18	-	-	HYPH
cord-026340-2nf97zvc	76	19	CoV	CoV	NNP
cord-026340-2nf97zvc	76	20	has	have	VBZ
cord-026340-2nf97zvc	76	21	91.02	91.02	CD
cord-026340-2nf97zvc	76	22	%	%	NN
cord-026340-2nf97zvc	76	23	and	and	CC
cord-026340-2nf97zvc	76	24	90.55	90.55	CD
cord-026340-2nf97zvc	76	25	%	%	NN
cord-026340-2nf97zvc	76	26	genetic	genetic	JJ
cord-026340-2nf97zvc	76	27	similarity	similarity	NN
cord-026340-2nf97zvc	76	28	to	to	IN
cord-026340-2nf97zvc	76	29	SARS	SARS	NNP
cord-026340-2nf97zvc	76	30	-	-	HYPH
cord-026340-2nf97zvc	76	31	CoV2	CoV2	NNP
cord-026340-2nf97zvc	76	32	and	and	CC
cord-026340-2nf97zvc	76	33	BatCoV	BatCoV	NNP
cord-026340-2nf97zvc	76	34	RaTG13	RaTG13	NNP
cord-026340-2nf97zvc	76	35	,	,	,
cord-026340-2nf97zvc	76	36	respectively	respectively	RB
cord-026340-2nf97zvc	76	37	,	,	,
cord-026340-2nf97zvc	76	38	and	and	CC
cord-026340-2nf97zvc	76	39	hence	hence	RB
cord-026340-2nf97zvc	76	40	contemplated	contemplate	VBD
cord-026340-2nf97zvc	76	41	to	to	TO
cord-026340-2nf97zvc	76	42	be	be	VB
cord-026340-2nf97zvc	76	43	one	one	CD
cord-026340-2nf97zvc	76	44	of	of	IN
cord-026340-2nf97zvc	76	45	the	the	DT
cord-026340-2nf97zvc	76	46	natural	natural	JJ
cord-026340-2nf97zvc	76	47	reservoirs	reservoir	NNS
cord-026340-2nf97zvc	76	48	of	of	IN
cord-026340-2nf97zvc	76	49	SARS	SARS	NNP
cord-026340-2nf97zvc	76	50	-	-	HYPH
cord-026340-2nf97zvc	76	51	CoV2	CoV2	NNP
cord-026340-2nf97zvc	76	52	.	.	.
cord-026340-2nf97zvc	77	1	What	what	WP
cord-026340-2nf97zvc	77	2	are	be	VBP
cord-026340-2nf97zvc	77	3	the	the	DT
cord-026340-2nf97zvc	77	4	symptoms	symptom	NNS
cord-026340-2nf97zvc	77	5	of	of	IN
cord-026340-2nf97zvc	77	6	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	77	7	?	?	.
cord-026340-2nf97zvc	78	1	For	for	IN
cord-026340-2nf97zvc	78	2	few	few	JJ
cord-026340-2nf97zvc	78	3	people	people	NNS
cord-026340-2nf97zvc	78	4	,	,	,
cord-026340-2nf97zvc	78	5	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	78	6	is	be	VBZ
cord-026340-2nf97zvc	78	7	mild	mild	JJ
cord-026340-2nf97zvc	78	8	with	with	IN
cord-026340-2nf97zvc	78	9	symptoms	symptom	NNS
cord-026340-2nf97zvc	78	10	like	like	IN
cord-026340-2nf97zvc	78	11	fever	fever	NN
cord-026340-2nf97zvc	78	12	,	,	,
cord-026340-2nf97zvc	78	13	cough	cough	NN
cord-026340-2nf97zvc	78	14	,	,	,
cord-026340-2nf97zvc	78	15	fatigue	fatigue	NN
cord-026340-2nf97zvc	78	16	,	,	,
cord-026340-2nf97zvc	78	17	aches	ache	NNS
cord-026340-2nf97zvc	78	18	and	and	CC
cord-026340-2nf97zvc	78	19	nasal	nasal	NN
cord-026340-2nf97zvc	78	20	congestion	congestion	NN
cord-026340-2nf97zvc	78	21	and	and	CC
cord-026340-2nf97zvc	78	22	in	in	IN
cord-026340-2nf97zvc	78	23	others	other	NNS
cord-026340-2nf97zvc	78	24	,	,	,
cord-026340-2nf97zvc	78	25	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	78	26	is	be	VBZ
cord-026340-2nf97zvc	78	27	asymptomatic	asymptomatic	JJ
cord-026340-2nf97zvc	78	28	.	.	.
cord-026340-2nf97zvc	79	1	The	the	DT
cord-026340-2nf97zvc	79	2	severe	severe	JJ
cord-026340-2nf97zvc	79	3	stage	stage	NN
cord-026340-2nf97zvc	79	4	of	of	IN
cord-026340-2nf97zvc	79	5	COVID-19	covid-19	NN
cord-026340-2nf97zvc	79	6	occurs	occur	VBZ
cord-026340-2nf97zvc	79	7	when	when	WRB
cord-026340-2nf97zvc	79	8	the	the	DT
cord-026340-2nf97zvc	79	9	infection	infection	NN
cord-026340-2nf97zvc	79	10	advances	advance	VBZ
cord-026340-2nf97zvc	79	11	to	to	IN
cord-026340-2nf97zvc	79	12	ARDS	ARDS	NNP
cord-026340-2nf97zvc	79	13	and	and	CC
cord-026340-2nf97zvc	79	14	multiple	multiple	JJ
cord-026340-2nf97zvc	79	15	organ	organ	NN
cord-026340-2nf97zvc	79	16	failure	failure	NN
cord-026340-2nf97zvc	79	17	mainly	mainly	RB
cord-026340-2nf97zvc	79	18	because	because	IN
cord-026340-2nf97zvc	79	19	of	of	IN
cord-026340-2nf97zvc	79	20	the	the	DT
cord-026340-2nf97zvc	79	21	inability	inability	NN
cord-026340-2nf97zvc	79	22	to	to	TO
cord-026340-2nf97zvc	79	23	control	control	VB
cord-026340-2nf97zvc	79	24	the	the	DT
cord-026340-2nf97zvc	79	25	'	'	``
cord-026340-2nf97zvc	79	26	cytokine	cytokine	NN
cord-026340-2nf97zvc	79	27	storm	storm	NN
cord-026340-2nf97zvc	79	28	'	'	''
cord-026340-2nf97zvc	79	29	or	or	CC
cord-026340-2nf97zvc	79	30	the	the	DT
cord-026340-2nf97zvc	79	31	wild	wild	JJ
cord-026340-2nf97zvc	79	32	cytokine	cytokine	NN
cord-026340-2nf97zvc	79	33	production	production	NN
cord-026340-2nf97zvc	79	34	taking	take	VBG
cord-026340-2nf97zvc	79	35	place	place	NN
cord-026340-2nf97zvc	79	36	in	in	IN
cord-026340-2nf97zvc	79	37	the	the	DT
cord-026340-2nf97zvc	79	38	body	body	NN
cord-026340-2nf97zvc	79	39	.	.	.
cord-026340-2nf97zvc	80	1	Increased	increase	VBN
cord-026340-2nf97zvc	80	2	age	age	NN
cord-026340-2nf97zvc	80	3	-	-	HYPH
cord-026340-2nf97zvc	80	4	related	relate	VBN
cord-026340-2nf97zvc	80	5	problems	problem	NNS
cord-026340-2nf97zvc	80	6	and	and	CC
cord-026340-2nf97zvc	80	7	medical	medical	JJ
cord-026340-2nf97zvc	80	8	complications	complication	NNS
cord-026340-2nf97zvc	80	9	like	like	IN
cord-026340-2nf97zvc	80	10	diabetes	diabetes	NN
cord-026340-2nf97zvc	80	11	,	,	,
cord-026340-2nf97zvc	80	12	blood	blood	NN
cord-026340-2nf97zvc	80	13	pressure	pressure	NN
cord-026340-2nf97zvc	80	14	or	or	CC
cord-026340-2nf97zvc	80	15	heart	heart	NN
cord-026340-2nf97zvc	80	16	diseases	disease	NNS
cord-026340-2nf97zvc	80	17	are	be	VBP
cord-026340-2nf97zvc	80	18	observed	observe	VBN
cord-026340-2nf97zvc	80	19	to	to	TO
cord-026340-2nf97zvc	80	20	worsen	worsen	VB
cord-026340-2nf97zvc	80	21	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	80	22	(	(	-LRB-
cord-026340-2nf97zvc	80	23	Tisoncik	Tisoncik	NNP
cord-026340-2nf97zvc	80	24	et	et	FW
cord-026340-2nf97zvc	80	25	al	al	NNP
cord-026340-2nf97zvc	80	26	.	.	.
cord-026340-2nf97zvc	81	1	2012	2012	CD
cord-026340-2nf97zvc	81	2	;	;	:
cord-026340-2nf97zvc	81	3	Abd	Abd	NNP
cord-026340-2nf97zvc	81	4	El	El	NNP
cord-026340-2nf97zvc	81	5	-	-	HYPH
cord-026340-2nf97zvc	81	6	Aziz	Aziz	NNP
cord-026340-2nf97zvc	81	7	and	and	CC
cord-026340-2nf97zvc	81	8	Stockand	Stockand	NNP
cord-026340-2nf97zvc	81	9	2020	2020	CD
cord-026340-2nf97zvc	81	10	;	;	:
cord-026340-2nf97zvc	81	11	Wang	Wang	NNP
cord-026340-2nf97zvc	81	12	and	and	CC
cord-026340-2nf97zvc	81	13	Mao	Mao	NNP
cord-026340-2nf97zvc	81	14	2020	2020	CD
cord-026340-2nf97zvc	81	15	)	)	-RRB-
cord-026340-2nf97zvc	81	16	.	.	.
cord-026340-2nf97zvc	82	1	Similarities	similarity	NNS
cord-026340-2nf97zvc	82	2	of	of	IN
cord-026340-2nf97zvc	82	3	SARS	SARS	NNP
cord-026340-2nf97zvc	82	4	-	-	:
cord-026340-2nf97zvc	82	5	CoV1	CoV1	NNP
cord-026340-2nf97zvc	82	6	and	and	CC
cord-026340-2nf97zvc	82	7	SARS	SARS	NNP
cord-026340-2nf97zvc	82	8	-	-	HYPH
cord-026340-2nf97zvc	82	9	CoV2	CoV2	NNP
cord-026340-2nf97zvc	82	10	:	:	:
cord-026340-2nf97zvc	83	1	SARS	SARS	NNP
cord-026340-2nf97zvc	83	2	CoV2	CoV2	NNP
cord-026340-2nf97zvc	83	3	shows	show	VBZ
cord-026340-2nf97zvc	83	4	some	some	DT
cord-026340-2nf97zvc	83	5	similarities	similarity	NNS
cord-026340-2nf97zvc	83	6	with	with	IN
cord-026340-2nf97zvc	83	7	SARS	SARS	NNP
cord-026340-2nf97zvc	84	1	CoV.	CoV.	NNP
cord-026340-2nf97zvc	84	2	SARS	SARS	NNP
cord-026340-2nf97zvc	84	3	CoV	CoV	NNP
cord-026340-2nf97zvc	84	4	originated	originate	VBD
cord-026340-2nf97zvc	84	5	in	in	IN
cord-026340-2nf97zvc	84	6	the	the	DT
cord-026340-2nf97zvc	84	7	Guangdong	Guangdong	NNP
cord-026340-2nf97zvc	84	8	province	province	NN
cord-026340-2nf97zvc	84	9	of	of	IN
cord-026340-2nf97zvc	84	10	China	China	NNP
cord-026340-2nf97zvc	84	11	in	in	IN
cord-026340-2nf97zvc	84	12	November	November	NNP
cord-026340-2nf97zvc	84	13	2002	2002	CD
cord-026340-2nf97zvc	84	14	.	.	.
cord-026340-2nf97zvc	85	1	Palm	palm	NN
cord-026340-2nf97zvc	85	2	civets	civet	NNS
cord-026340-2nf97zvc	85	3	were	be	VBD
cord-026340-2nf97zvc	85	4	identified	identify	VBN
cord-026340-2nf97zvc	85	5	as	as	IN
cord-026340-2nf97zvc	85	6	intermediary	intermediary	JJ
cord-026340-2nf97zvc	85	7	hosts	host	NNS
cord-026340-2nf97zvc	85	8	for	for	IN
cord-026340-2nf97zvc	85	9	SARS	SARS	NNP
cord-026340-2nf97zvc	85	10	CoV2	CoV2	NNP
cord-026340-2nf97zvc	85	11	which	which	WDT
cord-026340-2nf97zvc	85	12	contracted	contract	VBD
cord-026340-2nf97zvc	85	13	the	the	DT
cord-026340-2nf97zvc	85	14	virus	virus	NN
cord-026340-2nf97zvc	85	15	from	from	IN
cord-026340-2nf97zvc	85	16	bats	bat	NNS
cord-026340-2nf97zvc	85	17	(	(	-LRB-
cord-026340-2nf97zvc	85	18	Falsey	Falsey	NNP
cord-026340-2nf97zvc	85	19	and	and	CC
cord-026340-2nf97zvc	85	20	Walsh	Walsh	NNP
cord-026340-2nf97zvc	85	21	2003	2003	CD
cord-026340-2nf97zvc	85	22	)	)	-RRB-
cord-026340-2nf97zvc	85	23	.	.	.
cord-026340-2nf97zvc	86	1	SARS	SARS	NNP
cord-026340-2nf97zvc	86	2	-	-	HYPH
cord-026340-2nf97zvc	86	3	CoV	CoV	NNP
cord-026340-2nf97zvc	86	4	,	,	,
cord-026340-2nf97zvc	86	5	however	however	RB
cord-026340-2nf97zvc	86	6	,	,	,
cord-026340-2nf97zvc	86	7	was	be	VBD
cord-026340-2nf97zvc	86	8	more	more	RBR
cord-026340-2nf97zvc	86	9	`	`	''
cord-026340-2nf97zvc	86	10	severe	severe	JJ
cord-026340-2nf97zvc	86	11	than	than	IN
cord-026340-2nf97zvc	86	12	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	86	13	and	and	CC
cord-026340-2nf97zvc	86	14	produced	produce	VBD
cord-026340-2nf97zvc	86	15	influenza	influenza	NN
cord-026340-2nf97zvc	86	16	-	-	HYPH
cord-026340-2nf97zvc	86	17	like	like	JJ
cord-026340-2nf97zvc	86	18	symptoms	symptom	NNS
cord-026340-2nf97zvc	86	19	in	in	IN
cord-026340-2nf97zvc	86	20	humans	human	NNS
cord-026340-2nf97zvc	86	21	like	like	IN
cord-026340-2nf97zvc	86	22	fever	fever	NN
cord-026340-2nf97zvc	86	23	,	,	,
cord-026340-2nf97zvc	86	24	myalgia	myalgia	NN
cord-026340-2nf97zvc	86	25	,	,	,
cord-026340-2nf97zvc	86	26	headache	headache	NN
cord-026340-2nf97zvc	86	27	,	,	,
cord-026340-2nf97zvc	86	28	diarrhea	diarrhea	NN
cord-026340-2nf97zvc	86	29	,	,	,
cord-026340-2nf97zvc	86	30	shivering	shivering	NN
cord-026340-2nf97zvc	86	31	,	,	,
cord-026340-2nf97zvc	86	32	cough	cough	NN
cord-026340-2nf97zvc	86	33	and	and	CC
cord-026340-2nf97zvc	86	34	shortness	shortness	NN
cord-026340-2nf97zvc	86	35	of	of	IN
cord-026340-2nf97zvc	86	36	breath	breath	NN
cord-026340-2nf97zvc	86	37	.	.	.
cord-026340-2nf97zvc	87	1	WHO	who	WP
cord-026340-2nf97zvc	87	2	described	describe	VBD
cord-026340-2nf97zvc	87	3	the	the	DT
cord-026340-2nf97zvc	87	4	epidemic	epidemic	NN
cord-026340-2nf97zvc	87	5	as	as	IN
cord-026340-2nf97zvc	87	6	a	a	DT
cord-026340-2nf97zvc	87	7	serial	serial	JJ
cord-026340-2nf97zvc	87	8	killer	killer	NN
cord-026340-2nf97zvc	87	9	that	that	WDT
cord-026340-2nf97zvc	87	10	spanned	span	VBD
cord-026340-2nf97zvc	87	11	from	from	IN
cord-026340-2nf97zvc	87	12	16th	16th	JJ
cord-026340-2nf97zvc	87	13	November	November	NNP
cord-026340-2nf97zvc	87	14	2002	2002	CD
cord-026340-2nf97zvc	87	15	to	to	IN
cord-026340-2nf97zvc	87	16	5th	5th	JJ
cord-026340-2nf97zvc	87	17	September	September	NNP
cord-026340-2nf97zvc	87	18	2003	2003	CD
cord-026340-2nf97zvc	87	19	affecting	affect	VBG
cord-026340-2nf97zvc	87	20	8098	8098	CD
cord-026340-2nf97zvc	87	21	individuals	individual	NNS
cord-026340-2nf97zvc	87	22	in	in	IN
cord-026340-2nf97zvc	87	23	26	26	CD
cord-026340-2nf97zvc	87	24	different	different	JJ
cord-026340-2nf97zvc	87	25	nations	nation	NNS
cord-026340-2nf97zvc	87	26	and	and	CC
cord-026340-2nf97zvc	87	27	causing	cause	VBG
cord-026340-2nf97zvc	87	28	death	death	NN
cord-026340-2nf97zvc	87	29	of	of	IN
cord-026340-2nf97zvc	87	30	776	776	CD
cord-026340-2nf97zvc	87	31	people	people	NNS
cord-026340-2nf97zvc	87	32	(	(	-LRB-
cord-026340-2nf97zvc	87	33	mortality	mortality	NN
cord-026340-2nf97zvc	87	34	rate	rate	NN
cord-026340-2nf97zvc	87	35	of	of	IN
cord-026340-2nf97zvc	87	36	9.6	9.6	CD
cord-026340-2nf97zvc	87	37	%	%	NN
cord-026340-2nf97zvc	87	38	)	)	-RRB-
cord-026340-2nf97zvc	87	39	(	(	-LRB-
cord-026340-2nf97zvc	87	40	WHO	who	WP
cord-026340-2nf97zvc	87	41	2003	2003	CD
cord-026340-2nf97zvc	87	42	)	)	-RRB-
cord-026340-2nf97zvc	87	43	.	.	.
cord-026340-2nf97zvc	88	1	Presently	presently	RB
cord-026340-2nf97zvc	88	2	,	,	,
cord-026340-2nf97zvc	88	3	there	there	EX
cord-026340-2nf97zvc	88	4	are	be	VBP
cord-026340-2nf97zvc	88	5	reports	report	NNS
cord-026340-2nf97zvc	88	6	that	that	IN
cord-026340-2nf97zvc	88	7	SARS	SARS	NNP
cord-026340-2nf97zvc	88	8	-	-	HYPH
cord-026340-2nf97zvc	88	9	CoV2	CoV2	NNP
cord-026340-2nf97zvc	88	10	virus	virus	NN
cord-026340-2nf97zvc	88	11	is	be	VBZ
cord-026340-2nf97zvc	88	12	undergoing	undergo	VBG
cord-026340-2nf97zvc	88	13	mutations	mutation	NNS
cord-026340-2nf97zvc	88	14	similar	similar	JJ
cord-026340-2nf97zvc	88	15	to	to	IN
cord-026340-2nf97zvc	88	16	SARS	SARS	NNP
cord-026340-2nf97zvc	88	17	-	-	HYPH
cord-026340-2nf97zvc	88	18	CoV	CoV	NNP
cord-026340-2nf97zvc	88	19	virus	virus	NN
cord-026340-2nf97zvc	88	20	.	.	.
cord-026340-2nf97zvc	89	1	In	in	IN
cord-026340-2nf97zvc	89	2	both	both	DT
cord-026340-2nf97zvc	89	3	cases	case	NNS
cord-026340-2nf97zvc	89	4	,	,	,
cord-026340-2nf97zvc	89	5	mutations	mutation	NNS
cord-026340-2nf97zvc	89	6	have	have	VBP
cord-026340-2nf97zvc	89	7	occured	occur	VBN
cord-026340-2nf97zvc	89	8	in	in	IN
cord-026340-2nf97zvc	89	9	the	the	DT
cord-026340-2nf97zvc	89	10	spike	spike	NN
cord-026340-2nf97zvc	89	11	protein	protein	NN
cord-026340-2nf97zvc	89	12	.	.	.
cord-026340-2nf97zvc	90	1	This	this	DT
cord-026340-2nf97zvc	90	2	glycoprotein	glycoprotein	NN
cord-026340-2nf97zvc	90	3	is	be	VBZ
cord-026340-2nf97zvc	90	4	important	important	JJ
cord-026340-2nf97zvc	90	5	for	for	IN
cord-026340-2nf97zvc	90	6	the	the	DT
cord-026340-2nf97zvc	90	7	association	association	NN
cord-026340-2nf97zvc	90	8	of	of	IN
cord-026340-2nf97zvc	90	9	virus	virus	NN
cord-026340-2nf97zvc	90	10	with	with	IN
cord-026340-2nf97zvc	90	11	angiotensin	angiotensin	NN
cord-026340-2nf97zvc	90	12	-	-	HYPH
cord-026340-2nf97zvc	90	13	converting	convert	VBG
cord-026340-2nf97zvc	90	14	enzyme-2	enzyme-2	NNP
cord-026340-2nf97zvc	90	15	receptors	receptor	NNS
cord-026340-2nf97zvc	90	16	(	(	-LRB-
cord-026340-2nf97zvc	90	17	ACE2	ACE2	NNP
cord-026340-2nf97zvc	90	18	)	)	-RRB-
cord-026340-2nf97zvc	90	19	on	on	IN
cord-026340-2nf97zvc	90	20	cells	cell	NNS
cord-026340-2nf97zvc	90	21	of	of	IN
cord-026340-2nf97zvc	90	22	lung	lung	NN
cord-026340-2nf97zvc	90	23	,	,	,
cord-026340-2nf97zvc	90	24	intestine	intestine	NN
cord-026340-2nf97zvc	90	25	,	,	,
cord-026340-2nf97zvc	90	26	liver	liver	NN
cord-026340-2nf97zvc	90	27	,	,	,
cord-026340-2nf97zvc	90	28	heart	heart	NN
cord-026340-2nf97zvc	90	29	,	,	,
cord-026340-2nf97zvc	90	30	vascular	vascular	JJ
cord-026340-2nf97zvc	90	31	endothelium	endothelium	NN
cord-026340-2nf97zvc	90	32	,	,	,
cord-026340-2nf97zvc	90	33	testis	testis	NN
cord-026340-2nf97zvc	90	34	,	,	,
cord-026340-2nf97zvc	90	35	and	and	CC
cord-026340-2nf97zvc	90	36	kidney	kidney	NN
cord-026340-2nf97zvc	90	37	(	(	-LRB-
cord-026340-2nf97zvc	90	38	Hamming	ham	VBG
cord-026340-2nf97zvc	90	39	et	et	FW
cord-026340-2nf97zvc	90	40	al	al	NNP
cord-026340-2nf97zvc	90	41	.	.	.
cord-026340-2nf97zvc	90	42	2004	2004	CD
cord-026340-2nf97zvc	90	43	)	)	-RRB-
cord-026340-2nf97zvc	90	44	.	.	.
cord-026340-2nf97zvc	91	1	ACE2	ACE2	NNP
cord-026340-2nf97zvc	91	2	is	be	VBZ
cord-026340-2nf97zvc	91	3	part	part	NN
cord-026340-2nf97zvc	91	4	of	of	IN
cord-026340-2nf97zvc	91	5	the	the	DT
cord-026340-2nf97zvc	91	6	'	'	``
cord-026340-2nf97zvc	91	7	Renin	Renin	NNP
cord-026340-2nf97zvc	91	8	-	-	HYPH
cord-026340-2nf97zvc	91	9	Angiotensin	Angiotensin	NNP
cord-026340-2nf97zvc	91	10	'	'	POS
cord-026340-2nf97zvc	91	11	hormonal	hormonal	JJ
cord-026340-2nf97zvc	91	12	system	system	NN
cord-026340-2nf97zvc	91	13	of	of	IN
cord-026340-2nf97zvc	91	14	the	the	DT
cord-026340-2nf97zvc	91	15	body	body	NN
cord-026340-2nf97zvc	91	16	.	.	.
cord-026340-2nf97zvc	92	1	Structural	structural	JJ
cord-026340-2nf97zvc	92	2	and	and	CC
cord-026340-2nf97zvc	92	3	biochemical	biochemical	JJ
cord-026340-2nf97zvc	92	4	studies	study	NNS
cord-026340-2nf97zvc	92	5	conducted	conduct	VBN
cord-026340-2nf97zvc	92	6	so	so	RB
cord-026340-2nf97zvc	92	7	far	far	RB
cord-026340-2nf97zvc	92	8	have	have	VBP
cord-026340-2nf97zvc	92	9	shown	show	VBN
cord-026340-2nf97zvc	92	10	that	that	IN
cord-026340-2nf97zvc	92	11	S	s	NN
cord-026340-2nf97zvc	92	12	protein	protein	NN
cord-026340-2nf97zvc	92	13	of	of	IN
cord-026340-2nf97zvc	92	14	a	a	DT
cord-026340-2nf97zvc	92	15	SARS	SARS	NNP
cord-026340-2nf97zvc	92	16	virus	virus	NN
cord-026340-2nf97zvc	92	17	comprises	comprise	VBZ
cord-026340-2nf97zvc	92	18	of	of	IN
cord-026340-2nf97zvc	92	19	2	2	CD
cord-026340-2nf97zvc	92	20	functional	functional	JJ
cord-026340-2nf97zvc	92	21	subunits	subunit	NNS
cord-026340-2nf97zvc	92	22	.	.	.
cord-026340-2nf97zvc	93	1	(	(	-LRB-
cord-026340-2nf97zvc	93	2	i	i	NN
cord-026340-2nf97zvc	93	3	)	)	-RRB-
cord-026340-2nf97zvc	94	1	The	the	DT
cord-026340-2nf97zvc	94	2	S1	S1	NNP
cord-026340-2nf97zvc	94	3	subunit	subunit	NN
cord-026340-2nf97zvc	94	4	or	or	CC
cord-026340-2nf97zvc	94	5	receptor	receptor	NN
cord-026340-2nf97zvc	94	6	binding	bind	VBG
cord-026340-2nf97zvc	94	7	domain	domain	NN
cord-026340-2nf97zvc	94	8	is	be	VBZ
cord-026340-2nf97zvc	94	9	responsible	responsible	JJ
cord-026340-2nf97zvc	94	10	for	for	IN
cord-026340-2nf97zvc	94	11	binding	bind	VBG
cord-026340-2nf97zvc	94	12	of	of	IN
cord-026340-2nf97zvc	94	13	virus	virus	NN
cord-026340-2nf97zvc	94	14	to	to	TO
cord-026340-2nf97zvc	94	15	host	host	VB
cord-026340-2nf97zvc	94	16	cell	cell	NN
cord-026340-2nf97zvc	94	17	receptor	receptor	NN
cord-026340-2nf97zvc	94	18	and	and	CC
cord-026340-2nf97zvc	94	19	(	(	-LRB-
cord-026340-2nf97zvc	94	20	ii	ii	NN
cord-026340-2nf97zvc	94	21	)	)	-RRB-
cord-026340-2nf97zvc	94	22	S2	S2	NNP
cord-026340-2nf97zvc	94	23	is	be	VBZ
cord-026340-2nf97zvc	94	24	responsible	responsible	JJ
cord-026340-2nf97zvc	94	25	for	for	IN
cord-026340-2nf97zvc	94	26	fusion	fusion	NN
cord-026340-2nf97zvc	94	27	of	of	IN
cord-026340-2nf97zvc	94	28	virus	virus	NN
cord-026340-2nf97zvc	94	29	with	with	IN
cord-026340-2nf97zvc	94	30	cellular	cellular	JJ
cord-026340-2nf97zvc	94	31	membranes	membrane	NNS
cord-026340-2nf97zvc	94	32	.	.	.
cord-026340-2nf97zvc	95	1	Both	both	DT
cord-026340-2nf97zvc	95	2	sub	sub	NN
cord-026340-2nf97zvc	95	3	-	-	NNS
cord-026340-2nf97zvc	95	4	units	unit	NNS
cord-026340-2nf97zvc	95	5	are	be	VBP
cord-026340-2nf97zvc	95	6	separated	separate	VBN
cord-026340-2nf97zvc	95	7	but	but	CC
cord-026340-2nf97zvc	95	8	remain	remain	VBP
cord-026340-2nf97zvc	95	9	noncovalently	noncovalently	RB
cord-026340-2nf97zvc	95	10	bonded	bond	VBN
cord-026340-2nf97zvc	95	11	in	in	IN
cord-026340-2nf97zvc	95	12	a	a	DT
cord-026340-2nf97zvc	95	13	'	'	``
cord-026340-2nf97zvc	95	14	pre	pre	JJ
cord-026340-2nf97zvc	95	15	-	-	JJ
cord-026340-2nf97zvc	95	16	fusion	fusion	JJ
cord-026340-2nf97zvc	95	17	conformation	conformation	NN
cord-026340-2nf97zvc	95	18	'	'	''
cord-026340-2nf97zvc	95	19	stabilized	stabilize	VBN
cord-026340-2nf97zvc	95	20	by	by	IN
cord-026340-2nf97zvc	95	21	S1	S1	NNP
cord-026340-2nf97zvc	95	22	(	(	-LRB-
cord-026340-2nf97zvc	95	23	Andersen	Andersen	NNP
cord-026340-2nf97zvc	95	24	et	et	NNP
cord-026340-2nf97zvc	95	25	al	al	NNP
cord-026340-2nf97zvc	95	26	.	.	.
cord-026340-2nf97zvc	95	27	2020	2020	CD
cord-026340-2nf97zvc	95	28	;	;	:
cord-026340-2nf97zvc	95	29	Walls	Walls	NNPS
cord-026340-2nf97zvc	95	30	et	et	NNP
cord-026340-2nf97zvc	95	31	al	al	NNP
cord-026340-2nf97zvc	95	32	.	.	NNP
cord-026340-2nf97zvc	95	33	2020	2020	CD
cord-026340-2nf97zvc	95	34	)	)	-RRB-
cord-026340-2nf97zvc	95	35	.	.	.
cord-026340-2nf97zvc	96	1	Although	although	IN
cord-026340-2nf97zvc	96	2	both	both	DT
cord-026340-2nf97zvc	96	3	SARS	SARS	NNP
cord-026340-2nf97zvc	96	4	-	-	HYPH
cord-026340-2nf97zvc	96	5	CoV	CoV	NNP
cord-026340-2nf97zvc	96	6	and	and	CC
cord-026340-2nf97zvc	96	7	SARS	SARS	NNP
cord-026340-2nf97zvc	96	8	-	-	HYPH
cord-026340-2nf97zvc	96	9	CoV2	CoV2	NNP
cord-026340-2nf97zvc	96	10	viruses	virus	NNS
cord-026340-2nf97zvc	96	11	have	have	VBP
cord-026340-2nf97zvc	96	12	been	be	VBN
cord-026340-2nf97zvc	96	13	observed	observe	VBN
cord-026340-2nf97zvc	96	14	to	to	TO
cord-026340-2nf97zvc	96	15	infect	infect	VB
cord-026340-2nf97zvc	96	16	host	host	NN
cord-026340-2nf97zvc	96	17	cells	cell	NNS
cord-026340-2nf97zvc	96	18	via	via	IN
cord-026340-2nf97zvc	96	19	same	same	JJ
cord-026340-2nf97zvc	96	20	ACE	ace	NN
cord-026340-2nf97zvc	96	21	receptor	receptor	NN
cord-026340-2nf97zvc	96	22	,	,	,
cord-026340-2nf97zvc	96	23	there	there	EX
cord-026340-2nf97zvc	96	24	have	have	VBP
cord-026340-2nf97zvc	96	25	been	be	VBN
cord-026340-2nf97zvc	96	26	some	some	DT
cord-026340-2nf97zvc	96	27	differences	difference	NNS
cord-026340-2nf97zvc	96	28	noted	note	VBN
cord-026340-2nf97zvc	96	29	like	like	IN
cord-026340-2nf97zvc	96	30	an	an	DT
cord-026340-2nf97zvc	96	31	increased	increase	VBN
cord-026340-2nf97zvc	96	32	affinity	affinity	NN
cord-026340-2nf97zvc	96	33	of	of	IN
cord-026340-2nf97zvc	96	34	the	the	DT
cord-026340-2nf97zvc	96	35	virus	virus	NN
cord-026340-2nf97zvc	96	36	towards	towards	IN
cord-026340-2nf97zvc	96	37	the	the	DT
cord-026340-2nf97zvc	96	38	receptor	receptor	NN
cord-026340-2nf97zvc	96	39	in	in	IN
cord-026340-2nf97zvc	96	40	SARS	SARS	NNP
cord-026340-2nf97zvc	96	41	CoV2	CoV2	NNP
cord-026340-2nf97zvc	96	42	.	.	.
cord-026340-2nf97zvc	97	1	This	this	DT
cord-026340-2nf97zvc	97	2	has	have	VBZ
cord-026340-2nf97zvc	97	3	been	be	VBN
cord-026340-2nf97zvc	97	4	presumed	presume	VBN
cord-026340-2nf97zvc	97	5	to	to	TO
cord-026340-2nf97zvc	97	6	be	be	VB
cord-026340-2nf97zvc	97	7	due	due	JJ
cord-026340-2nf97zvc	97	8	to	to	IN
cord-026340-2nf97zvc	97	9	a	a	DT
cord-026340-2nf97zvc	97	10	mutation	mutation	NN
cord-026340-2nf97zvc	97	11	,	,	,
cord-026340-2nf97zvc	97	12	i.e.	i.e.	FW
cord-026340-2nf97zvc	97	13	,	,	,
cord-026340-2nf97zvc	97	14	N501	N501	NNP
cord-026340-2nf97zvc	97	15	T	t	NN
cord-026340-2nf97zvc	97	16	in	in	IN
cord-026340-2nf97zvc	97	17	spike	spike	NN
cord-026340-2nf97zvc	97	18	protein	protein	NN
cord-026340-2nf97zvc	97	19	of	of	IN
cord-026340-2nf97zvc	97	20	SARS	SARS	NNP
cord-026340-2nf97zvc	97	21	-	-	HYPH
cord-026340-2nf97zvc	97	22	CoV2	CoV2	NNP
cord-026340-2nf97zvc	97	23	that	that	WDT
cord-026340-2nf97zvc	97	24	has	have	VBZ
cord-026340-2nf97zvc	97	25	somehow	somehow	RB
cord-026340-2nf97zvc	97	26	increased	increase	VBN
cord-026340-2nf97zvc	97	27	the	the	DT
cord-026340-2nf97zvc	97	28	binding	bind	VBG
cord-026340-2nf97zvc	97	29	affinity	affinity	NN
cord-026340-2nf97zvc	97	30	of	of	IN
cord-026340-2nf97zvc	97	31	virus	virus	NN
cord-026340-2nf97zvc	97	32	for	for	IN
cord-026340-2nf97zvc	97	33	ACE2	ACE2	NNP
cord-026340-2nf97zvc	98	1	(	(	-LRB-
cord-026340-2nf97zvc	98	2	Andersen	Andersen	NNP
cord-026340-2nf97zvc	98	3	et	et	NNP
cord-026340-2nf97zvc	98	4	al	al	NNP
cord-026340-2nf97zvc	98	5	.	.	NNP
cord-026340-2nf97zvc	98	6	2020	2020	CD
cord-026340-2nf97zvc	98	7	)	)	-RRB-
cord-026340-2nf97zvc	98	8	.	.	.
cord-026340-2nf97zvc	99	1	Very	very	RB
cord-026340-2nf97zvc	99	2	recent	recent	JJ
cord-026340-2nf97zvc	99	3	reports	report	NNS
cord-026340-2nf97zvc	99	4	demonstrate	demonstrate	VBP
cord-026340-2nf97zvc	99	5	that	that	IN
cord-026340-2nf97zvc	99	6	the	the	DT
cord-026340-2nf97zvc	99	7	S1	S1	NNP
cord-026340-2nf97zvc	99	8	protein	protein	NN
cord-026340-2nf97zvc	99	9	of	of	IN
cord-026340-2nf97zvc	99	10	Pangolin	Pangolin	NNP
cord-026340-2nf97zvc	99	11	-	-	HYPH
cord-026340-2nf97zvc	99	12	CoV	CoV	NNP
cord-026340-2nf97zvc	99	13	is	be	VBZ
cord-026340-2nf97zvc	99	14	similar	similar	JJ
cord-026340-2nf97zvc	99	15	to	to	IN
cord-026340-2nf97zvc	99	16	SARS	SARS	NNP
cord-026340-2nf97zvc	99	17	CoV2	CoV2	NNP
cord-026340-2nf97zvc	99	18	than	than	IN
cord-026340-2nf97zvc	99	19	RaTG13	RaTG13	NNP
cord-026340-2nf97zvc	99	20	.	.	.
cord-026340-2nf97zvc	100	1	There	there	EX
cord-026340-2nf97zvc	100	2	is	be	VBZ
cord-026340-2nf97zvc	100	3	evidence	evidence	NN
cord-026340-2nf97zvc	100	4	that	that	IN
cord-026340-2nf97zvc	100	5	5	5	CD
cord-026340-2nf97zvc	100	6	key	key	JJ
cord-026340-2nf97zvc	100	7	amino	amino	NN
cord-026340-2nf97zvc	100	8	acid	acid	NN
cord-026340-2nf97zvc	100	9	residues	residue	NNS
cord-026340-2nf97zvc	100	10	in	in	IN
cord-026340-2nf97zvc	100	11	spike	spike	NN
cord-026340-2nf97zvc	100	12	protein	protein	NN
cord-026340-2nf97zvc	100	13	that	that	WDT
cord-026340-2nf97zvc	100	14	are	be	VBP
cord-026340-2nf97zvc	100	15	in	in	IN
cord-026340-2nf97zvc	100	16	interaction	interaction	NN
cord-026340-2nf97zvc	100	17	with	with	IN
cord-026340-2nf97zvc	100	18	human	human	JJ
cord-026340-2nf97zvc	100	19	ACE2	ACE2	NNP
cord-026340-2nf97zvc	100	20	are	be	VBP
cord-026340-2nf97zvc	100	21	consistent	consistent	JJ
cord-026340-2nf97zvc	100	22	between	between	IN
cord-026340-2nf97zvc	100	23	Pangolin	Pangolin	NNP
cord-026340-2nf97zvc	100	24	and	and	CC
cord-026340-2nf97zvc	100	25	SARS	SARS	NNP
cord-026340-2nf97zvc	100	26	-	-	HYPH
cord-026340-2nf97zvc	100	27	CoV2	CoV2	NNP
cord-026340-2nf97zvc	100	28	;	;	:
cord-026340-2nf97zvc	100	29	while	while	IN
cord-026340-2nf97zvc	100	30	,	,	,
cord-026340-2nf97zvc	100	31	only	only	RB
cord-026340-2nf97zvc	100	32	4	4	CD
cord-026340-2nf97zvc	100	33	amino	amino	NN
cord-026340-2nf97zvc	100	34	acid	acid	NN
cord-026340-2nf97zvc	100	35	mutations	mutation	NNS
cord-026340-2nf97zvc	100	36	are	be	VBP
cord-026340-2nf97zvc	100	37	present	present	JJ
cord-026340-2nf97zvc	100	38	in	in	IN
cord-026340-2nf97zvc	100	39	RaTG13	RaTG13	NNP
cord-026340-2nf97zvc	100	40	.	.	.
cord-026340-2nf97zvc	101	1	Nonetheless	nonetheless	RB
cord-026340-2nf97zvc	101	2	,	,	,
cord-026340-2nf97zvc	101	3	both	both	DT
cord-026340-2nf97zvc	101	4	Pangolin	Pangolin	NNP
cord-026340-2nf97zvc	101	5	-	-	HYPH
cord-026340-2nf97zvc	101	6	CoV	CoV	NNP
cord-026340-2nf97zvc	101	7	and	and	CC
cord-026340-2nf97zvc	101	8	RaTG12	RaTG12	NNS
cord-026340-2nf97zvc	101	9	have	have	VBP
cord-026340-2nf97zvc	101	10	lost	lose	VBN
cord-026340-2nf97zvc	101	11	putative	putative	JJ
cord-026340-2nf97zvc	101	12	furin	furin	NN
cord-026340-2nf97zvc	101	13	recognition	recognition	NN
cord-026340-2nf97zvc	101	14	at	at	IN
cord-026340-2nf97zvc	101	15	S1	S1	NNP
cord-026340-2nf97zvc	101	16	/	/	SYM
cord-026340-2nf97zvc	101	17	S2	S2	NNP
cord-026340-2nf97zvc	101	18	cleavage	cleavage	NN
cord-026340-2nf97zvc	101	19	site	site	NN
cord-026340-2nf97zvc	101	20	that	that	WDT
cord-026340-2nf97zvc	101	21	is	be	VBZ
cord-026340-2nf97zvc	101	22	seen	see	VBN
cord-026340-2nf97zvc	101	23	in	in	IN
cord-026340-2nf97zvc	101	24	SARS	SARS	NNP
cord-026340-2nf97zvc	101	25	CoV2	CoV2	NNP
cord-026340-2nf97zvc	101	26	.	.	.
cord-026340-2nf97zvc	102	1	These	these	DT
cord-026340-2nf97zvc	102	2	data	datum	NNS
cord-026340-2nf97zvc	102	3	emerge	emerge	VBP
cord-026340-2nf97zvc	102	4	from	from	IN
cord-026340-2nf97zvc	102	5	findings	finding	NNS
cord-026340-2nf97zvc	102	6	of	of	IN
cord-026340-2nf97zvc	102	7	Liu	Liu	NNP
cord-026340-2nf97zvc	102	8	et	et	NNP
cord-026340-2nf97zvc	102	9	al	al	NNP
cord-026340-2nf97zvc	102	10	.	.	.
cord-026340-2nf97zvc	103	1	(	(	-LRB-
cord-026340-2nf97zvc	103	2	2019	2019	CD
cord-026340-2nf97zvc	103	3	)	)	-RRB-
cord-026340-2nf97zvc	103	4	who	who	WP
cord-026340-2nf97zvc	103	5	detected	detect	VBD
cord-026340-2nf97zvc	103	6	corona	corona	NN
cord-026340-2nf97zvc	103	7	viruses	virus	NNS
cord-026340-2nf97zvc	103	8	in	in	IN
cord-026340-2nf97zvc	103	9	lung	lung	NN
cord-026340-2nf97zvc	103	10	-	-	HYPH
cord-026340-2nf97zvc	103	11	infected	infect	VBN
cord-026340-2nf97zvc	103	12	samples	sample	NNS
cord-026340-2nf97zvc	103	13	of	of	IN
cord-026340-2nf97zvc	103	14	dead	dead	JJ
cord-026340-2nf97zvc	103	15	Malayan	malayan	JJ
cord-026340-2nf97zvc	103	16	pangolins	pangolin	NNS
cord-026340-2nf97zvc	103	17	along	along	IN
cord-026340-2nf97zvc	103	18	with	with	IN
cord-026340-2nf97zvc	103	19	Sendai	Sendai	NNP
cord-026340-2nf97zvc	103	20	virus	virus	NN
cord-026340-2nf97zvc	103	21	from	from	IN
cord-026340-2nf97zvc	103	22	the	the	DT
cord-026340-2nf97zvc	103	23	Guangdong	Guangdong	NNP
cord-026340-2nf97zvc	103	24	wildlife	wildlife	NN
cord-026340-2nf97zvc	103	25	rescue	rescue	NN
cord-026340-2nf97zvc	103	26	center	center	NN
cord-026340-2nf97zvc	103	27	of	of	IN
cord-026340-2nf97zvc	103	28	China	China	NNP
cord-026340-2nf97zvc	103	29	which	which	WDT
cord-026340-2nf97zvc	103	30	showed	show	VBD
cord-026340-2nf97zvc	103	31	low	low	JJ
cord-026340-2nf97zvc	103	32	identities	identity	NNS
cord-026340-2nf97zvc	103	33	ranging	range	VBG
cord-026340-2nf97zvc	103	34	from	from	IN
cord-026340-2nf97zvc	103	35	80.24	80.24	CD
cord-026340-2nf97zvc	103	36	to	to	IN
cord-026340-2nf97zvc	103	37	88.93	88.93	CD
cord-026340-2nf97zvc	103	38	%	%	NN
cord-026340-2nf97zvc	103	39	with	with	IN
cord-026340-2nf97zvc	103	40	known	know	VBN
cord-026340-2nf97zvc	103	41	SARS	SARS	NNP
cord-026340-2nf97zvc	103	42	-	-	HYPH
cord-026340-2nf97zvc	103	43	CoV.	CoV.	NNP
cord-026340-2nf97zvc	104	1	What	what	WP
cord-026340-2nf97zvc	104	2	are	be	VBP
cord-026340-2nf97zvc	104	3	the	the	DT
cord-026340-2nf97zvc	104	4	possible	possible	JJ
cord-026340-2nf97zvc	104	5	ways	way	NNS
cord-026340-2nf97zvc	104	6	SARS	SARS	NNP
cord-026340-2nf97zvc	104	7	-	-	HYPH
cord-026340-2nf97zvc	104	8	CoV2	CoV2	NNS
cord-026340-2nf97zvc	104	9	infect	infect	VBP
cord-026340-2nf97zvc	104	10	a	a	DT
cord-026340-2nf97zvc	104	11	host	host	NN
cord-026340-2nf97zvc	104	12	cell	cell	NN
cord-026340-2nf97zvc	104	13	?	?	.
cord-026340-2nf97zvc	105	1	From	from	IN
cord-026340-2nf97zvc	105	2	the	the	DT
cord-026340-2nf97zvc	105	3	available	available	JJ
cord-026340-2nf97zvc	105	4	data	datum	NNS
cord-026340-2nf97zvc	105	5	we	-PRON-	PRP
cord-026340-2nf97zvc	105	6	have	have	VBP
cord-026340-2nf97zvc	105	7	concise	concise	JJ
cord-026340-2nf97zvc	105	8	the	the	DT
cord-026340-2nf97zvc	105	9	information	information	NN
cord-026340-2nf97zvc	105	10	pertaining	pertain	VBG
cord-026340-2nf97zvc	105	11	to	to	IN
cord-026340-2nf97zvc	105	12	SARS	SARS	NNP
cord-026340-2nf97zvc	105	13	-	-	HYPH
cord-026340-2nf97zvc	105	14	CoV2	cov2	NN
cord-026340-2nf97zvc	105	15	infection	infection	NN
cord-026340-2nf97zvc	105	16	into	into	IN
cord-026340-2nf97zvc	105	17	host	host	NN
cord-026340-2nf97zvc	105	18	cell	cell	NN
cord-026340-2nf97zvc	105	19	that	that	WDT
cord-026340-2nf97zvc	105	20	is	be	VBZ
cord-026340-2nf97zvc	105	21	depicted	depict	VBN
cord-026340-2nf97zvc	105	22	as	as	IN
cord-026340-2nf97zvc	105	23	Fig	Fig	NNP
cord-026340-2nf97zvc	105	24	.	.	.
cord-026340-2nf97zvc	106	1	1	1	LS
cord-026340-2nf97zvc	106	2	.	.	.
cord-026340-2nf97zvc	107	1	Step	step	NN
cord-026340-2nf97zvc	107	2	1	1	CD
cord-026340-2nf97zvc	107	3	Entry	Entry	NNP
cord-026340-2nf97zvc	107	4	of	of	IN
cord-026340-2nf97zvc	107	5	virus	virus	NN
cord-026340-2nf97zvc	108	1	:	:	:
cord-026340-2nf97zvc	108	2	Viral	viral	JJ
cord-026340-2nf97zvc	108	3	entry	entry	NN
cord-026340-2nf97zvc	108	4	is	be	VBZ
cord-026340-2nf97zvc	108	5	a	a	DT
cord-026340-2nf97zvc	108	6	fine	fine	JJ
cord-026340-2nf97zvc	108	7	interplay	interplay	NN
cord-026340-2nf97zvc	108	8	between	between	IN
cord-026340-2nf97zvc	108	9	the	the	DT
cord-026340-2nf97zvc	108	10	virion	virion	NN
cord-026340-2nf97zvc	108	11	and	and	CC
cord-026340-2nf97zvc	108	12	the	the	DT
cord-026340-2nf97zvc	108	13	host	host	NN
cord-026340-2nf97zvc	108	14	cell	cell	NN
cord-026340-2nf97zvc	108	15	and	and	CC
cord-026340-2nf97zvc	108	16	is	be	VBZ
cord-026340-2nf97zvc	108	17	initiated	initiate	VBN
cord-026340-2nf97zvc	108	18	by	by	IN
cord-026340-2nf97zvc	108	19	association	association	NN
cord-026340-2nf97zvc	108	20	of	of	IN
cord-026340-2nf97zvc	108	21	the	the	DT
cord-026340-2nf97zvc	108	22	viral	viral	JJ
cord-026340-2nf97zvc	108	23	particle	particle	NN
cord-026340-2nf97zvc	108	24	with	with	IN
cord-026340-2nf97zvc	108	25	specific	specific	JJ
cord-026340-2nf97zvc	108	26	proteins	protein	NNS
cord-026340-2nf97zvc	108	27	on	on	IN
cord-026340-2nf97zvc	108	28	the	the	DT
cord-026340-2nf97zvc	108	29	host	host	NN
cord-026340-2nf97zvc	108	30	cell	cell	NN
cord-026340-2nf97zvc	108	31	surface	surface	NN
cord-026340-2nf97zvc	108	32	.	.	.
cord-026340-2nf97zvc	109	1	Thereafter	thereafter	RB
cord-026340-2nf97zvc	109	2	,	,	,
cord-026340-2nf97zvc	109	3	the	the	DT
cord-026340-2nf97zvc	109	4	enveloped	envelop	VBN
cord-026340-2nf97zvc	109	5	viruses	virus	NNS
cord-026340-2nf97zvc	109	6	fuse	fuse	VBP
cord-026340-2nf97zvc	109	7	their	-PRON-	PRP$
cord-026340-2nf97zvc	109	8	envelope	envelope	NN
cord-026340-2nf97zvc	109	9	with	with	IN
cord-026340-2nf97zvc	109	10	the	the	DT
cord-026340-2nf97zvc	109	11	host	host	NN
cord-026340-2nf97zvc	109	12	cell	cell	NN
cord-026340-2nf97zvc	109	13	membrane	membrane	NN
cord-026340-2nf97zvc	109	14	to	to	TO
cord-026340-2nf97zvc	109	15	deliver	deliver	VB
cord-026340-2nf97zvc	109	16	their	-PRON-	PRP$
cord-026340-2nf97zvc	109	17	nucleocapsid	nucleocapsid	NN
cord-026340-2nf97zvc	109	18	to	to	IN
cord-026340-2nf97zvc	109	19	the	the	DT
cord-026340-2nf97zvc	109	20	host	host	NN
cord-026340-2nf97zvc	109	21	cell	cell	NN
cord-026340-2nf97zvc	109	22	.	.	.
cord-026340-2nf97zvc	110	1	The	the	DT
cord-026340-2nf97zvc	110	2	S	S	NNP
cord-026340-2nf97zvc	110	3	protein	protein	NN
cord-026340-2nf97zvc	110	4	plays	play	VBZ
cord-026340-2nf97zvc	110	5	a	a	DT
cord-026340-2nf97zvc	110	6	dual	dual	JJ
cord-026340-2nf97zvc	110	7	role	role	NN
cord-026340-2nf97zvc	110	8	in	in	IN
cord-026340-2nf97zvc	110	9	this	this	DT
cord-026340-2nf97zvc	110	10	viral	viral	JJ
cord-026340-2nf97zvc	110	11	entry	entry	NN
cord-026340-2nf97zvc	110	12	process	process	NN
cord-026340-2nf97zvc	110	13	by	by	IN
cord-026340-2nf97zvc	110	14	mediating	mediate	VBG
cord-026340-2nf97zvc	110	15	receptor	receptor	NN
cord-026340-2nf97zvc	110	16	binding	binding	NN
cord-026340-2nf97zvc	110	17	and	and	CC
cord-026340-2nf97zvc	110	18	membrane	membrane	NN
cord-026340-2nf97zvc	110	19	fusion	fusion	NN
cord-026340-2nf97zvc	110	20	,	,	,
cord-026340-2nf97zvc	110	21	which	which	WDT
cord-026340-2nf97zvc	110	22	involves	involve	VBZ
cord-026340-2nf97zvc	110	23	large	large	JJ
cord-026340-2nf97zvc	110	24	conformational	conformational	JJ
cord-026340-2nf97zvc	110	25	changes	change	NNS
cord-026340-2nf97zvc	110	26	of	of	IN
cord-026340-2nf97zvc	110	27	the	the	DT
cord-026340-2nf97zvc	110	28	S	S	NNP
cord-026340-2nf97zvc	110	29	protein	protein	NN
cord-026340-2nf97zvc	110	30	.	.	.
cord-026340-2nf97zvc	111	1	During	during	IN
cord-026340-2nf97zvc	111	2	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	111	3	,	,	,
cord-026340-2nf97zvc	111	4	SARS	SARS	NNP
cord-026340-2nf97zvc	111	5	-	-	HYPH
cord-026340-2nf97zvc	111	6	CoV2	CoV2	NNP
cord-026340-2nf97zvc	111	7	S	s	NN
cord-026340-2nf97zvc	111	8	-	-	HYPH
cord-026340-2nf97zvc	111	9	protein	protein	NN
cord-026340-2nf97zvc	111	10	binds	bind	VBZ
cord-026340-2nf97zvc	111	11	to	to	TO
cord-026340-2nf97zvc	111	12	host	host	VB
cord-026340-2nf97zvc	111	13	cell	cell	NN
cord-026340-2nf97zvc	111	14	's	's	POS
cord-026340-2nf97zvc	111	15	receptor	receptor	NN
cord-026340-2nf97zvc	111	16	ACE2	ACE2	NNP
cord-026340-2nf97zvc	112	1	(	(	-LRB-
cord-026340-2nf97zvc	112	2	Belouzard	Belouzard	NNP
cord-026340-2nf97zvc	112	3	et	et	NNP
cord-026340-2nf97zvc	112	4	al	al	NNP
cord-026340-2nf97zvc	112	5	.	.	.
cord-026340-2nf97zvc	113	1	2012	2012	CD
cord-026340-2nf97zvc	113	2	;	;	:
cord-026340-2nf97zvc	113	3	Andersen	Andersen	NNP
cord-026340-2nf97zvc	113	4	et	et	NNP
cord-026340-2nf97zvc	113	5	al	al	NNP
cord-026340-2nf97zvc	113	6	.	.	.
cord-026340-2nf97zvc	114	1	2020	2020	CD
cord-026340-2nf97zvc	114	2	)	)	-RRB-
cord-026340-2nf97zvc	115	1	Step	step	NN
cord-026340-2nf97zvc	115	2	2	2	CD
cord-026340-2nf97zvc	116	1	The	the	DT
cord-026340-2nf97zvc	116	2	activation	activation	NN
cord-026340-2nf97zvc	116	3	of	of	IN
cord-026340-2nf97zvc	116	4	the	the	DT
cord-026340-2nf97zvc	116	5	virus	virus	NN
cord-026340-2nf97zvc	116	6	:	:	:
cord-026340-2nf97zvc	117	1	Endosomal	Endosomal	NNP
cord-026340-2nf97zvc	117	2	pH	pH	NNP
cord-026340-2nf97zvc	117	3	acidification	acidification	NN
cord-026340-2nf97zvc	117	4	is	be	VBZ
cord-026340-2nf97zvc	117	5	a	a	DT
cord-026340-2nf97zvc	117	6	fusion	fusion	NN
cord-026340-2nf97zvc	117	7	trigger	trigger	NN
cord-026340-2nf97zvc	117	8	for	for	IN
cord-026340-2nf97zvc	117	9	corona	corona	NN
cord-026340-2nf97zvc	117	10	viruses	virus	NNS
cord-026340-2nf97zvc	117	11	and	and	CC
cord-026340-2nf97zvc	117	12	those	those	DT
cord-026340-2nf97zvc	117	13	like	like	IN
cord-026340-2nf97zvc	117	14	SARS	SARS	NNP
cord-026340-2nf97zvc	117	15	-	-	HYPH
cord-026340-2nf97zvc	117	16	CoV	CoV	NNP
cord-026340-2nf97zvc	117	17	rely	rely	VBP
cord-026340-2nf97zvc	117	18	on	on	IN
cord-026340-2nf97zvc	117	19	endosomal	endosomal	NNP
cord-026340-2nf97zvc	117	20	proteases	protease	NNS
cord-026340-2nf97zvc	117	21	for	for	IN
cord-026340-2nf97zvc	117	22	productive	productive	JJ
cord-026340-2nf97zvc	117	23	entry	entry	NN
cord-026340-2nf97zvc	117	24	.	.	.
cord-026340-2nf97zvc	118	1	As	as	IN
cord-026340-2nf97zvc	118	2	virus	virus	NN
cord-026340-2nf97zvc	118	3	enters	enter	VBZ
cord-026340-2nf97zvc	118	4	the	the	DT
cord-026340-2nf97zvc	118	5	host	host	NN
cord-026340-2nf97zvc	118	6	cell	cell	NN
cord-026340-2nf97zvc	118	7	,	,	,
cord-026340-2nf97zvc	118	8	it	-PRON-	PRP
cord-026340-2nf97zvc	118	9	moves	move	VBZ
cord-026340-2nf97zvc	118	10	through	through	IN
cord-026340-2nf97zvc	118	11	the	the	DT
cord-026340-2nf97zvc	118	12	early	early	JJ
cord-026340-2nf97zvc	118	13	and	and	CC
cord-026340-2nf97zvc	118	14	late	late	JJ
cord-026340-2nf97zvc	118	15	endosomes	endosome	NNS
cord-026340-2nf97zvc	118	16	that	that	WDT
cord-026340-2nf97zvc	118	17	have	have	VBP
cord-026340-2nf97zvc	118	18	low	low	JJ
cord-026340-2nf97zvc	118	19	pH.	ph.	NN
cord-026340-2nf97zvc	119	1	In	in	IN
cord-026340-2nf97zvc	119	2	'	'	``
cord-026340-2nf97zvc	119	3	early	early	JJ
cord-026340-2nf97zvc	119	4	'	'	''
cord-026340-2nf97zvc	119	5	endosome	endosome	NN
cord-026340-2nf97zvc	119	6	,	,	,
cord-026340-2nf97zvc	119	7	host	host	NN
cord-026340-2nf97zvc	119	8	proteases	protease	NNS
cord-026340-2nf97zvc	119	9	like	like	IN
cord-026340-2nf97zvc	119	10	cathepsin	cathepsin	NN
cord-026340-2nf97zvc	119	11	L	l	NN
cord-026340-2nf97zvc	119	12	facilitates	facilitate	VBZ
cord-026340-2nf97zvc	119	13	cleavage	cleavage	NN
cord-026340-2nf97zvc	119	14	of	of	IN
cord-026340-2nf97zvc	119	15	S	s	NN
cord-026340-2nf97zvc	119	16	protein	protein	NN
cord-026340-2nf97zvc	119	17	in	in	IN
cord-026340-2nf97zvc	119	18	the	the	DT
cord-026340-2nf97zvc	119	19	S1-S2	S1-S2	NNP
cord-026340-2nf97zvc	119	20	boundary	boundary	JJ
cord-026340-2nf97zvc	119	21	region	region	NN
cord-026340-2nf97zvc	119	22	leading	lead	VBG
cord-026340-2nf97zvc	119	23	to	to	IN
cord-026340-2nf97zvc	119	24	fusion	fusion	NN
cord-026340-2nf97zvc	119	25	of	of	IN
cord-026340-2nf97zvc	119	26	the	the	DT
cord-026340-2nf97zvc	119	27	viral	viral	JJ
cord-026340-2nf97zvc	119	28	envelope	envelope	NN
cord-026340-2nf97zvc	119	29	.	.	.
cord-026340-2nf97zvc	120	1	Enzyme	enzyme	NN
cord-026340-2nf97zvc	120	2	digestion	digestion	NN
cord-026340-2nf97zvc	120	3	experiments	experiment	NNS
cord-026340-2nf97zvc	120	4	have	have	VBP
cord-026340-2nf97zvc	120	5	shown	show	VBN
cord-026340-2nf97zvc	120	6	that	that	IN
cord-026340-2nf97zvc	120	7	first	first	JJ
cord-026340-2nf97zvc	120	8	cleavage	cleavage	NN
cord-026340-2nf97zvc	120	9	event	event	NN
cord-026340-2nf97zvc	120	10	at	at	IN
cord-026340-2nf97zvc	120	11	the	the	DT
cord-026340-2nf97zvc	120	12	S1-S2	S1-S2	NNP
cord-026340-2nf97zvc	120	13	boundary	boundary	NN
cord-026340-2nf97zvc	120	14	probably	probably	RB
cord-026340-2nf97zvc	120	15	enables	enable	VBZ
cord-026340-2nf97zvc	120	16	the	the	DT
cord-026340-2nf97zvc	120	17	second	second	JJ
cord-026340-2nf97zvc	120	18	cleavage	cleavage	NN
cord-026340-2nf97zvc	120	19	event	event	NN
cord-026340-2nf97zvc	120	20	at	at	IN
cord-026340-2nf97zvc	120	21	S2	S2	NNP
cord-026340-2nf97zvc	120	22	'	'	''
cord-026340-2nf97zvc	120	23	region	region	NN
cord-026340-2nf97zvc	120	24	,	,	,
cord-026340-2nf97zvc	120	25	that	that	DT
cord-026340-2nf97zvc	120	26	is	be	VBZ
cord-026340-2nf97zvc	120	27	responsible	responsible	JJ
cord-026340-2nf97zvc	120	28	for	for	IN
cord-026340-2nf97zvc	120	29	fusion	fusion	NN
cord-026340-2nf97zvc	120	30	activation	activation	NN
cord-026340-2nf97zvc	120	31	.	.	.
cord-026340-2nf97zvc	121	1	SARS	SARS	NNP
cord-026340-2nf97zvc	121	2	-	-	HYPH
cord-026340-2nf97zvc	121	3	CoV	CoV	NNP
cord-026340-2nf97zvc	121	4	spike	spike	NN
cord-026340-2nf97zvc	121	5	protein	protein	NN
cord-026340-2nf97zvc	121	6	also	also	RB
cord-026340-2nf97zvc	121	7	exhibits	exhibit	VBZ
cord-026340-2nf97zvc	121	8	a	a	DT
cord-026340-2nf97zvc	121	9	certain	certain	JJ
cord-026340-2nf97zvc	121	10	degree	degree	NN
cord-026340-2nf97zvc	121	11	of	of	IN
cord-026340-2nf97zvc	121	12	plasticity	plasticity	NN
cord-026340-2nf97zvc	121	13	in	in	IN
cord-026340-2nf97zvc	121	14	the	the	DT
cord-026340-2nf97zvc	121	15	position	position	NN
cord-026340-2nf97zvc	121	16	of	of	IN
cord-026340-2nf97zvc	121	17	the	the	DT
cord-026340-2nf97zvc	121	18	cleavage	cleavage	NN
cord-026340-2nf97zvc	121	19	site	site	NN
cord-026340-2nf97zvc	121	20	for	for	IN
cord-026340-2nf97zvc	121	21	priming	prime	VBG
cord-026340-2nf97zvc	121	22	of	of	IN
cord-026340-2nf97zvc	122	1	fusion	fusion	NNP
cord-026340-2nf97zvc	122	2	SARS	SARS	NNP
cord-026340-2nf97zvc	122	3	-	-	HYPH
cord-026340-2nf97zvc	122	4	CoV.	CoV.	NNP
cord-026340-2nf97zvc	123	1	In	in	IN
cord-026340-2nf97zvc	123	2	'	'	``
cord-026340-2nf97zvc	123	3	late	late	JJ
cord-026340-2nf97zvc	123	4	'	'	''
cord-026340-2nf97zvc	123	5	endosome	endosome	NN
cord-026340-2nf97zvc	123	6	,	,	,
cord-026340-2nf97zvc	123	7	the	the	DT
cord-026340-2nf97zvc	123	8	viral	viral	JJ
cord-026340-2nf97zvc	123	9	genome	genome	NN
cord-026340-2nf97zvc	123	10	with	with	IN
cord-026340-2nf97zvc	123	11	its	-PRON-	PRP$
cord-026340-2nf97zvc	123	12	nucleocapsid	nucleocapsid	NN
cord-026340-2nf97zvc	123	13	is	be	VBZ
cord-026340-2nf97zvc	123	14	released	release	VBN
cord-026340-2nf97zvc	123	15	into	into	IN
cord-026340-2nf97zvc	123	16	the	the	DT
cord-026340-2nf97zvc	123	17	host	host	NN
cord-026340-2nf97zvc	123	18	cytoplasm	cytoplasm	NN
cord-026340-2nf97zvc	124	1	(	(	-LRB-
cord-026340-2nf97zvc	124	2	Cassell	Cassell	NNP
cord-026340-2nf97zvc	124	3	et	et	NNP
cord-026340-2nf97zvc	124	4	al	al	NNP
cord-026340-2nf97zvc	124	5	.	.	.
cord-026340-2nf97zvc	125	1	1984	1984	CD
cord-026340-2nf97zvc	125	2	;	;	:
cord-026340-2nf97zvc	125	3	Yang	Yang	NNP
cord-026340-2nf97zvc	125	4	et	et	NNP
cord-026340-2nf97zvc	125	5	al	al	NNP
cord-026340-2nf97zvc	125	6	.	.	.
cord-026340-2nf97zvc	126	1	2004	2004	CD
cord-026340-2nf97zvc	126	2	;	;	:
cord-026340-2nf97zvc	126	3	Wang	Wang	NNP
cord-026340-2nf97zvc	126	4	et	et	NNP
cord-026340-2nf97zvc	126	5	al	al	NNP
cord-026340-2nf97zvc	126	6	.	.	.
cord-026340-2nf97zvc	127	1	2008	2008	CD
cord-026340-2nf97zvc	127	2	;	;	:
cord-026340-2nf97zvc	127	3	Belouzard	Belouzard	NNP
cord-026340-2nf97zvc	127	4	et	et	NNP
cord-026340-2nf97zvc	127	5	al	al	NNP
cord-026340-2nf97zvc	127	6	.	.	.
cord-026340-2nf97zvc	128	1	2012	2012	CD
cord-026340-2nf97zvc	128	2	)	)	-RRB-
cord-026340-2nf97zvc	129	1	Step	step	NN
cord-026340-2nf97zvc	129	2	3	3	CD
cord-026340-2nf97zvc	129	3	Viral	viral	JJ
cord-026340-2nf97zvc	129	4	replication	replication	NN
cord-026340-2nf97zvc	129	5	:	:	:
cord-026340-2nf97zvc	129	6	Replication	replication	NN
cord-026340-2nf97zvc	129	7	occurs	occur	VBZ
cord-026340-2nf97zvc	129	8	in	in	IN
cord-026340-2nf97zvc	129	9	the	the	DT
cord-026340-2nf97zvc	129	10	cell	cell	NN
cord-026340-2nf97zvc	129	11	cytoplasm	cytoplasm	NN
cord-026340-2nf97zvc	129	12	and	and	CC
cord-026340-2nf97zvc	129	13	the	the	DT
cord-026340-2nf97zvc	129	14	positive	positive	JJ
cord-026340-2nf97zvc	129	15	-	-	HYPH
cord-026340-2nf97zvc	129	16	strand	strand	NN
cord-026340-2nf97zvc	129	17	viral	viral	JJ
cord-026340-2nf97zvc	129	18	genomic	genomic	NN
cord-026340-2nf97zvc	129	19	RNA	RNA	NNP
cord-026340-2nf97zvc	129	20	is	be	VBZ
cord-026340-2nf97zvc	129	21	transcribed	transcribe	VBN
cord-026340-2nf97zvc	129	22	into	into	IN
cord-026340-2nf97zvc	129	23	a	a	DT
cord-026340-2nf97zvc	129	24	negative	negative	JJ
cord-026340-2nf97zvc	129	25	RNA	RNA	NNP
cord-026340-2nf97zvc	129	26	strand	strand	NN
cord-026340-2nf97zvc	129	27	that	that	WDT
cord-026340-2nf97zvc	129	28	is	be	VBZ
cord-026340-2nf97zvc	129	29	used	use	VBN
cord-026340-2nf97zvc	129	30	as	as	IN
cord-026340-2nf97zvc	129	31	a	a	DT
cord-026340-2nf97zvc	129	32	template	template	NN
cord-026340-2nf97zvc	129	33	for	for	IN
cord-026340-2nf97zvc	129	34	the	the	DT
cord-026340-2nf97zvc	129	35	synthesis	synthesis	NN
cord-026340-2nf97zvc	129	36	of	of	IN
cord-026340-2nf97zvc	129	37	viral	viral	JJ
cord-026340-2nf97zvc	129	38	mRNA	mrna	NN
cord-026340-2nf97zvc	129	39	(	(	-LRB-
cord-026340-2nf97zvc	129	40	Devaux	Devaux	NNP
cord-026340-2nf97zvc	129	41	et	et	NNP
cord-026340-2nf97zvc	129	42	al	al	NNP
cord-026340-2nf97zvc	129	43	.	.	NNP
cord-026340-2nf97zvc	129	44	2020	2020	CD
cord-026340-2nf97zvc	129	45	)	)	-RRB-
cord-026340-2nf97zvc	130	1	Step	step	NN
cord-026340-2nf97zvc	130	2	4	4	CD
cord-026340-2nf97zvc	131	1	Viral	viral	JJ
cord-026340-2nf97zvc	131	2	protein	protein	NN
cord-026340-2nf97zvc	131	3	synthesis	synthesis	NN
cord-026340-2nf97zvc	131	4	:	:	:
cord-026340-2nf97zvc	132	1	ORF1a	ORF1a	NNP
cord-026340-2nf97zvc	132	2	and	and	CC
cord-026340-2nf97zvc	132	3	ORF1b	ORF1b	NNP
cord-026340-2nf97zvc	132	4	genes	gene	NNS
cord-026340-2nf97zvc	132	5	of	of	IN
cord-026340-2nf97zvc	132	6	viral	viral	JJ
cord-026340-2nf97zvc	132	7	genome	genome	NN
cord-026340-2nf97zvc	132	8	produce	produce	VBP
cord-026340-2nf97zvc	132	9	two	two	CD
cord-026340-2nf97zvc	132	10	polyproteins	polyprotein	NNS
cord-026340-2nf97zvc	132	11	(	(	-LRB-
cord-026340-2nf97zvc	132	12	PPs	pp	NNS
cord-026340-2nf97zvc	132	13	)	)	-RRB-
cord-026340-2nf97zvc	132	14	that	that	WDT
cord-026340-2nf97zvc	132	15	are	be	VBP
cord-026340-2nf97zvc	132	16	pp1a	pp1a	NNP
cord-026340-2nf97zvc	132	17	and	and	CC
cord-026340-2nf97zvc	132	18	pp1b	pp1b	NNP
cord-026340-2nf97zvc	132	19	which	which	WDT
cord-026340-2nf97zvc	132	20	takeover	takeover	NN
cord-026340-2nf97zvc	132	21	host	host	NN
cord-026340-2nf97zvc	132	22	ribosomes	ribosome	VBZ
cord-026340-2nf97zvc	132	23	for	for	IN
cord-026340-2nf97zvc	132	24	their	-PRON-	PRP$
cord-026340-2nf97zvc	132	25	own	own	JJ
cord-026340-2nf97zvc	132	26	translation	translation	NN
cord-026340-2nf97zvc	132	27	and	and	CC
cord-026340-2nf97zvc	132	28	replication	replication	NN
cord-026340-2nf97zvc	132	29	.	.	.
cord-026340-2nf97zvc	133	1	As	as	IN
cord-026340-2nf97zvc	133	2	ribosome	ribosome	NN
cord-026340-2nf97zvc	133	3	machinery	machinery	NN
cord-026340-2nf97zvc	133	4	of	of	IN
cord-026340-2nf97zvc	133	5	the	the	DT
cord-026340-2nf97zvc	133	6	infected	infected	JJ
cord-026340-2nf97zvc	133	7	cells	cell	NNS
cord-026340-2nf97zvc	133	8	moves	move	NNS
cord-026340-2nf97zvc	133	9	in	in	IN
cord-026340-2nf97zvc	133	10	favor	favor	NN
cord-026340-2nf97zvc	133	11	of	of	IN
cord-026340-2nf97zvc	133	12	the	the	DT
cord-026340-2nf97zvc	133	13	virus	virus	NN
cord-026340-2nf97zvc	133	14	,	,	,
cord-026340-2nf97zvc	133	15	it	-PRON-	PRP
cord-026340-2nf97zvc	133	16	synthesizes	synthesize	VBZ
cord-026340-2nf97zvc	133	17	non	non	JJ
cord-026340-2nf97zvc	133	18	-	-	JJ
cord-026340-2nf97zvc	133	19	structural	structural	JJ
cord-026340-2nf97zvc	133	20	proteins	protein	NNS
cord-026340-2nf97zvc	133	21	(	(	-LRB-
cord-026340-2nf97zvc	133	22	NSPs	NSPs	NNP
cord-026340-2nf97zvc	133	23	)	)	-RRB-
cord-026340-2nf97zvc	133	24	for	for	IN
cord-026340-2nf97zvc	133	25	virus	virus	NN
cord-026340-2nf97zvc	133	26	.	.	.
cord-026340-2nf97zvc	134	1	These	these	DT
cord-026340-2nf97zvc	134	2	assemble	assemble	VBP
cord-026340-2nf97zvc	134	3	into	into	IN
cord-026340-2nf97zvc	134	4	the	the	DT
cord-026340-2nf97zvc	134	5	replicase	replicase	NN
cord-026340-2nf97zvc	134	6	-	-	HYPH
cord-026340-2nf97zvc	134	7	transcriptase	transcriptase	NN
cord-026340-2nf97zvc	134	8	complex	complex	NN
cord-026340-2nf97zvc	134	9	to	to	TO
cord-026340-2nf97zvc	134	10	support	support	VB
cord-026340-2nf97zvc	134	11	viral	viral	JJ
cord-026340-2nf97zvc	134	12	subgenomic	subgenomic	NNP
cord-026340-2nf97zvc	134	13	mRNA	mRNA	NNP
cord-026340-2nf97zvc	134	14	synthesis	synthesis	NNP
cord-026340-2nf97zvc	134	15	.	.	.
cord-026340-2nf97zvc	135	1	NSP1	NSP1	NNP
cord-026340-2nf97zvc	135	2	and	and	CC
cord-026340-2nf97zvc	135	3	NSP2	NSP2	NNP
cord-026340-2nf97zvc	135	4	have	have	VBP
cord-026340-2nf97zvc	135	5	specific	specific	JJ
cord-026340-2nf97zvc	135	6	functions	function	NNS
cord-026340-2nf97zvc	135	7	such	such	JJ
cord-026340-2nf97zvc	135	8	as	as	IN
cord-026340-2nf97zvc	135	9	suppression	suppression	NN
cord-026340-2nf97zvc	135	10	of	of	IN
cord-026340-2nf97zvc	135	11	host	host	NN
cord-026340-2nf97zvc	135	12	gene	gene	NN
cord-026340-2nf97zvc	135	13	expression	expression	NN
cord-026340-2nf97zvc	135	14	(	(	-LRB-
cord-026340-2nf97zvc	135	15	Schoeman	Schoeman	NNP
cord-026340-2nf97zvc	135	16	and	and	CC
cord-026340-2nf97zvc	135	17	Fielding	Fielding	NNP
cord-026340-2nf97zvc	135	18	2019	2019	CD
cord-026340-2nf97zvc	135	19	;	;	:
cord-026340-2nf97zvc	135	20	Devaux	Devaux	NNP
cord-026340-2nf97zvc	135	21	et	et	NNP
cord-026340-2nf97zvc	135	22	al	al	NNP
cord-026340-2nf97zvc	135	23	.	.	.
cord-026340-2nf97zvc	136	1	2020	2020	CD
cord-026340-2nf97zvc	136	2	;	;	:
cord-026340-2nf97zvc	136	3	Prajapat	Prajapat	NNP
cord-026340-2nf97zvc	136	4	et	et	NNP
cord-026340-2nf97zvc	136	5	al	al	NNP
cord-026340-2nf97zvc	136	6	.	.	NNP
cord-026340-2nf97zvc	136	7	2020	2020	CD
cord-026340-2nf97zvc	136	8	)	)	-RRB-
cord-026340-2nf97zvc	137	1	Step	step	NN
cord-026340-2nf97zvc	137	2	5	5	CD
cord-026340-2nf97zvc	137	3	Transport	transport	NN
cord-026340-2nf97zvc	137	4	across	across	IN
cord-026340-2nf97zvc	137	5	ER	ER	NNP
cord-026340-2nf97zvc	137	6	and	and	CC
cord-026340-2nf97zvc	137	7	TGN	TGN	NNP
cord-026340-2nf97zvc	138	1	(	(	-LRB-
cord-026340-2nf97zvc	138	2	Trans	Trans	NNP
cord-026340-2nf97zvc	138	3	-	-	NNP
cord-026340-2nf97zvc	138	4	Golgi	Golgi	NNP
cord-026340-2nf97zvc	138	5	network	network	NN
cord-026340-2nf97zvc	138	6	)	)	-RRB-
cord-026340-2nf97zvc	138	7	:	:	:
cord-026340-2nf97zvc	138	8	After	after	IN
cord-026340-2nf97zvc	138	9	replication	replication	NN
cord-026340-2nf97zvc	138	10	,	,	,
cord-026340-2nf97zvc	138	11	the	the	DT
cord-026340-2nf97zvc	138	12	envelope	envelope	NN
cord-026340-2nf97zvc	138	13	proteins	protein	NNS
cord-026340-2nf97zvc	138	14	such	such	JJ
cord-026340-2nf97zvc	138	15	as	as	IN
cord-026340-2nf97zvc	138	16	M	M	NNP
cord-026340-2nf97zvc	138	17	,	,	,
cord-026340-2nf97zvc	138	18	E	E	NNP
cord-026340-2nf97zvc	138	19	,	,	,
cord-026340-2nf97zvc	138	20	and	and	CC
cord-026340-2nf97zvc	138	21	S	S	NNP
cord-026340-2nf97zvc	138	22	are	be	VBP
cord-026340-2nf97zvc	138	23	translated	translate	VBN
cord-026340-2nf97zvc	138	24	and	and	CC
cord-026340-2nf97zvc	138	25	gets	get	VBZ
cord-026340-2nf97zvc	138	26	transport	transport	NN
cord-026340-2nf97zvc	138	27	towards	towards	IN
cord-026340-2nf97zvc	138	28	the	the	DT
cord-026340-2nf97zvc	138	29	endoplasmic	endoplasmic	NN
cord-026340-2nf97zvc	138	30	reticulum	reticulum	NN
cord-026340-2nf97zvc	138	31	(	(	-LRB-
cord-026340-2nf97zvc	138	32	ER)-Golgi	ER)-Golgi	NNP
cord-026340-2nf97zvc	138	33	intermediate	intermediate	JJ
cord-026340-2nf97zvc	138	34	compartment	compartment	NN
cord-026340-2nf97zvc	138	35	(	(	-LRB-
cord-026340-2nf97zvc	138	36	ERGIC	ERGIC	NNP
cord-026340-2nf97zvc	138	37	)	)	-RRB-
cord-026340-2nf97zvc	138	38	complex	complex	JJ
cord-026340-2nf97zvc	138	39	to	to	TO
cord-026340-2nf97zvc	138	40	form	form	VB
cord-026340-2nf97zvc	138	41	the	the	DT
cord-026340-2nf97zvc	138	42	structure	structure	NN
cord-026340-2nf97zvc	138	43	of	of	IN
cord-026340-2nf97zvc	138	44	viral	viral	JJ
cord-026340-2nf97zvc	138	45	envelope	envelope	NN
cord-026340-2nf97zvc	138	46	.	.	.
cord-026340-2nf97zvc	139	1	Replicated	replicate	VBN
cord-026340-2nf97zvc	139	2	genome	genome	NN
cord-026340-2nf97zvc	139	3	binds	bind	VBZ
cord-026340-2nf97zvc	139	4	to	to	IN
cord-026340-2nf97zvc	139	5	N	n	CD
cord-026340-2nf97zvc	139	6	protein	protein	NN
cord-026340-2nf97zvc	139	7	and	and	CC
cord-026340-2nf97zvc	139	8	forms	form	VBZ
cord-026340-2nf97zvc	139	9	the	the	DT
cord-026340-2nf97zvc	139	10	ribonucleoprotein	ribonucleoprotein	NN
cord-026340-2nf97zvc	139	11	(	(	-LRB-
cord-026340-2nf97zvc	139	12	RNP	RNP	NNP
cord-026340-2nf97zvc	139	13	)	)	-RRB-
cord-026340-2nf97zvc	139	14	complex	complex	JJ
cord-026340-2nf97zvc	139	15	(	(	-LRB-
cord-026340-2nf97zvc	139	16	Prajapat	Prajapat	NNP
cord-026340-2nf97zvc	139	17	et	et	NNP
cord-026340-2nf97zvc	139	18	al	al	NNP
cord-026340-2nf97zvc	139	19	.	.	NNP
cord-026340-2nf97zvc	139	20	2020	2020	CD
cord-026340-2nf97zvc	139	21	)	)	-RRB-
cord-026340-2nf97zvc	140	1	Step	step	NN
cord-026340-2nf97zvc	140	2	6	6	CD
cord-026340-2nf97zvc	140	3	Assembly	assembly	NN
cord-026340-2nf97zvc	140	4	:	:	:
cord-026340-2nf97zvc	141	1	Viral	viral	JJ
cord-026340-2nf97zvc	141	2	genomic	genomic	NN
cord-026340-2nf97zvc	141	3	RNA	RNA	NNP
cord-026340-2nf97zvc	141	4	is	be	VBZ
cord-026340-2nf97zvc	141	5	then	then	RB
cord-026340-2nf97zvc	141	6	packed	pack	VBN
cord-026340-2nf97zvc	141	7	into	into	IN
cord-026340-2nf97zvc	141	8	the	the	DT
cord-026340-2nf97zvc	141	9	nucleocapsid	nucleocapsid	NN
cord-026340-2nf97zvc	141	10	and	and	CC
cord-026340-2nf97zvc	141	11	then	then	RB
cord-026340-2nf97zvc	141	12	envelope	envelope	NN
cord-026340-2nf97zvc	141	13	proteins	protein	NNS
cord-026340-2nf97zvc	141	14	are	be	VBP
cord-026340-2nf97zvc	141	15	included	include	VBN
cord-026340-2nf97zvc	141	16	during	during	IN
cord-026340-2nf97zvc	141	17	the	the	DT
cord-026340-2nf97zvc	141	18	budding	budding	JJ
cord-026340-2nf97zvc	141	19	step	step	NN
cord-026340-2nf97zvc	141	20	to	to	TO
cord-026340-2nf97zvc	141	21	form	form	VB
cord-026340-2nf97zvc	141	22	mature	mature	JJ
cord-026340-2nf97zvc	141	23	virions	virion	NNS
cord-026340-2nf97zvc	141	24	.	.	.
cord-026340-2nf97zvc	142	1	The	the	DT
cord-026340-2nf97zvc	142	2	M	M	NNP
cord-026340-2nf97zvc	142	3	protein	protein	NN
cord-026340-2nf97zvc	142	4	,	,	,
cord-026340-2nf97zvc	142	5	which	which	WDT
cord-026340-2nf97zvc	142	6	localizes	localize	VBZ
cord-026340-2nf97zvc	142	7	to	to	IN
cord-026340-2nf97zvc	142	8	the	the	DT
cord-026340-2nf97zvc	142	9	trans	trans	NNP
cord-026340-2nf97zvc	142	10	-	-	NNP
cord-026340-2nf97zvc	142	11	Golgi	Golgi	NNP
cord-026340-2nf97zvc	142	12	network	network	NN
cord-026340-2nf97zvc	142	13	,	,	,
cord-026340-2nf97zvc	142	14	plays	play	VBZ
cord-026340-2nf97zvc	142	15	an	an	DT
cord-026340-2nf97zvc	142	16	essential	essential	JJ
cord-026340-2nf97zvc	142	17	role	role	NN
cord-026340-2nf97zvc	142	18	during	during	IN
cord-026340-2nf97zvc	142	19	viral	viral	JJ
cord-026340-2nf97zvc	142	20	assembly	assembly	NN
cord-026340-2nf97zvc	142	21	by	by	IN
cord-026340-2nf97zvc	142	22	interacting	interact	VBG
cord-026340-2nf97zvc	142	23	with	with	IN
cord-026340-2nf97zvc	142	24	the	the	DT
cord-026340-2nf97zvc	142	25	other	other	JJ
cord-026340-2nf97zvc	142	26	proteins	protein	NNS
cord-026340-2nf97zvc	142	27	of	of	IN
cord-026340-2nf97zvc	142	28	the	the	DT
cord-026340-2nf97zvc	142	29	virus	virus	NN
cord-026340-2nf97zvc	142	30	mRNA	mrna	NN
cord-026340-2nf97zvc	142	31	(	(	-LRB-
cord-026340-2nf97zvc	142	32	Devaux	Devaux	NNP
cord-026340-2nf97zvc	142	33	et	et	NNP
cord-026340-2nf97zvc	142	34	al	al	NNP
cord-026340-2nf97zvc	142	35	.	.	NNP
cord-026340-2nf97zvc	142	36	2020	2020	CD
cord-026340-2nf97zvc	142	37	)	)	-RRB-
cord-026340-2nf97zvc	143	1	Step	step	NN
cord-026340-2nf97zvc	143	2	7	7	CD
cord-026340-2nf97zvc	143	3	Budding	budding	NN
cord-026340-2nf97zvc	143	4	and	and	CC
cord-026340-2nf97zvc	143	5	exocytosis	exocytosis	NN
cord-026340-2nf97zvc	143	6	:	:	:
cord-026340-2nf97zvc	144	1	Further	further	RB
cord-026340-2nf97zvc	144	2	after	after	IN
cord-026340-2nf97zvc	144	3	assembly	assembly	NN
cord-026340-2nf97zvc	144	4	,	,	,
cord-026340-2nf97zvc	144	5	the	the	DT
cord-026340-2nf97zvc	144	6	virus	virus	NN
cord-026340-2nf97zvc	144	7	particle	particle	NN
cord-026340-2nf97zvc	144	8	comes	come	VBZ
cord-026340-2nf97zvc	144	9	out	out	IN
cord-026340-2nf97zvc	144	10	of	of	IN
cord-026340-2nf97zvc	144	11	the	the	DT
cord-026340-2nf97zvc	144	12	ERGIC	ERGIC	NNP
cord-026340-2nf97zvc	144	13	via	via	IN
cord-026340-2nf97zvc	144	14	a	a	DT
cord-026340-2nf97zvc	144	15	budlike	budlike	JJ
cord-026340-2nf97zvc	144	16	structure	structure	NN
cord-026340-2nf97zvc	144	17	.	.	.
cord-026340-2nf97zvc	145	1	The	the	DT
cord-026340-2nf97zvc	145	2	budding	budding	NN
cord-026340-2nf97zvc	145	3	is	be	VBZ
cord-026340-2nf97zvc	145	4	determined	determine	VBN
cord-026340-2nf97zvc	145	5	by	by	IN
cord-026340-2nf97zvc	145	6	the	the	DT
cord-026340-2nf97zvc	145	7	localization	localization	NN
cord-026340-2nf97zvc	145	8	of	of	IN
cord-026340-2nf97zvc	145	9	its	-PRON-	PRP$
cord-026340-2nf97zvc	145	10	membrane	membrane	NN
cord-026340-2nf97zvc	145	11	protein	protein	NN
cord-026340-2nf97zvc	145	12	M	M	NNP
cord-026340-2nf97zvc	145	13	and	and	CC
cord-026340-2nf97zvc	145	14	finally	finally	RB
cord-026340-2nf97zvc	145	15	,	,	,
cord-026340-2nf97zvc	145	16	newly	newly	RB
cord-026340-2nf97zvc	145	17	formed	form	VBN
cord-026340-2nf97zvc	145	18	viral	viral	JJ
cord-026340-2nf97zvc	145	19	particles	particle	NNS
cord-026340-2nf97zvc	145	20	are	be	VBP
cord-026340-2nf97zvc	145	21	transported	transport	VBN
cord-026340-2nf97zvc	145	22	to	to	IN
cord-026340-2nf97zvc	145	23	the	the	DT
cord-026340-2nf97zvc	145	24	cell	cell	NN
cord-026340-2nf97zvc	145	25	surface	surface	NN
cord-026340-2nf97zvc	145	26	in	in	IN
cord-026340-2nf97zvc	145	27	vesicles	vesicle	NNS
cord-026340-2nf97zvc	145	28	and	and	CC
cord-026340-2nf97zvc	145	29	are	be	VBP
cord-026340-2nf97zvc	145	30	released	release	VBN
cord-026340-2nf97zvc	145	31	by	by	IN
cord-026340-2nf97zvc	145	32	exocytosis	exocytosis	NN
cord-026340-2nf97zvc	145	33	mRNA	mRNA	NNP
cord-026340-2nf97zvc	146	1	(	(	-LRB-
cord-026340-2nf97zvc	146	2	Devaux	Devaux	NNP
cord-026340-2nf97zvc	146	3	et	et	NNP
cord-026340-2nf97zvc	146	4	al	al	NNP
cord-026340-2nf97zvc	146	5	.	.	NNP
cord-026340-2nf97zvc	146	6	2020	2020	CD
cord-026340-2nf97zvc	146	7	)	)	-RRB-
cord-026340-2nf97zvc	147	1	Plasma	plasma	NN
cord-026340-2nf97zvc	147	2	Membrane	membrane	NN
cord-026340-2nf97zvc	147	3	Step	step	NN
cord-026340-2nf97zvc	147	4	1	1	CD
cord-026340-2nf97zvc	147	5	Step	Step	NNP
cord-026340-2nf97zvc	147	6	2	2	CD
cord-026340-2nf97zvc	147	7	Step	Step	NNP
cord-026340-2nf97zvc	147	8	3	3	CD
cord-026340-2nf97zvc	147	9	Step	Step	NNP
cord-026340-2nf97zvc	147	10	4	4	CD
cord-026340-2nf97zvc	147	11	Step	step	NN
cord-026340-2nf97zvc	147	12	5	5	CD
cord-026340-2nf97zvc	147	13	Step	Step	NNP
cord-026340-2nf97zvc	147	14	6	6	CD
cord-026340-2nf97zvc	147	15	Step	Step	NNP
cord-026340-2nf97zvc	147	16	7	7	CD
cord-026340-2nf97zvc	148	1	The	the	DT
cord-026340-2nf97zvc	148	2	mechanism	mechanism	NN
cord-026340-2nf97zvc	148	3	of	of	IN
cord-026340-2nf97zvc	148	4	viral	viral	JJ
cord-026340-2nf97zvc	148	5	infection	infection	NN
cord-026340-2nf97zvc	148	6	is	be	VBZ
cord-026340-2nf97zvc	148	7	still	still	RB
cord-026340-2nf97zvc	148	8	not	not	RB
cord-026340-2nf97zvc	148	9	complete	complete	JJ
cord-026340-2nf97zvc	148	10	and	and	CC
cord-026340-2nf97zvc	148	11	under	under	IN
cord-026340-2nf97zvc	148	12	study	study	NN
cord-026340-2nf97zvc	148	13	.	.	.
cord-026340-2nf97zvc	149	1	So	so	RB
cord-026340-2nf97zvc	149	2	far	far	RB
cord-026340-2nf97zvc	149	3	,	,	,
cord-026340-2nf97zvc	149	4	the	the	DT
cord-026340-2nf97zvc	149	5	data	datum	NNS
cord-026340-2nf97zvc	149	6	show	show	VBP
cord-026340-2nf97zvc	149	7	that	that	IN
cord-026340-2nf97zvc	149	8	the	the	DT
cord-026340-2nf97zvc	149	9	activation	activation	NN
cord-026340-2nf97zvc	149	10	of	of	IN
cord-026340-2nf97zvc	149	11	the	the	DT
cord-026340-2nf97zvc	149	12	virus	virus	NN
cord-026340-2nf97zvc	149	13	occurs	occur	VBZ
cord-026340-2nf97zvc	149	14	as	as	IN
cord-026340-2nf97zvc	149	15	it	-PRON-	PRP
cord-026340-2nf97zvc	149	16	enters	enter	VBZ
cord-026340-2nf97zvc	149	17	the	the	DT
cord-026340-2nf97zvc	149	18	host	host	NN
cord-026340-2nf97zvc	149	19	cell	cell	NN
cord-026340-2nf97zvc	149	20	.	.	.
cord-026340-2nf97zvc	150	1	During	during	IN
cord-026340-2nf97zvc	150	2	this	this	DT
cord-026340-2nf97zvc	150	3	time	time	NN
cord-026340-2nf97zvc	150	4	,	,	,
cord-026340-2nf97zvc	150	5	a	a	DT
cord-026340-2nf97zvc	150	6	cleavage	cleavage	NN
cord-026340-2nf97zvc	150	7	process	process	NN
cord-026340-2nf97zvc	150	8	occurs	occur	VBZ
cord-026340-2nf97zvc	150	9	at	at	IN
cord-026340-2nf97zvc	150	10	polybasic	polybasic	NNP
cord-026340-2nf97zvc	150	11	(	(	-LRB-
cord-026340-2nf97zvc	150	12	furin	furin	NN
cord-026340-2nf97zvc	150	13	)	)	-RRB-
cord-026340-2nf97zvc	150	14	cleavage	cleavage	NN
cord-026340-2nf97zvc	150	15	site	site	NN
cord-026340-2nf97zvc	150	16	at	at	IN
cord-026340-2nf97zvc	150	17	S1-S2	S1-S2	NNP
cord-026340-2nf97zvc	150	18	boundary	boundary	NN
cord-026340-2nf97zvc	150	19	(	(	-LRB-
cord-026340-2nf97zvc	150	20	formed	form	VBN
cord-026340-2nf97zvc	150	21	by	by	IN
cord-026340-2nf97zvc	150	22	insertion	insertion	NN
cord-026340-2nf97zvc	150	23	of	of	IN
cord-026340-2nf97zvc	150	24	12	12	CD
cord-026340-2nf97zvc	150	25	nucleotides	nucleotide	NNS
cord-026340-2nf97zvc	150	26	)	)	-RRB-
cord-026340-2nf97zvc	150	27	,	,	,
cord-026340-2nf97zvc	150	28	which	which	WDT
cord-026340-2nf97zvc	150	29	is	be	VBZ
cord-026340-2nf97zvc	150	30	followed	follow	VBN
cord-026340-2nf97zvc	150	31	by	by	IN
cord-026340-2nf97zvc	150	32	an	an	DT
cord-026340-2nf97zvc	150	33	irreversible	irreversible	JJ
cord-026340-2nf97zvc	150	34	conformational	conformational	JJ
cord-026340-2nf97zvc	150	35	change	change	NN
cord-026340-2nf97zvc	150	36	.	.	.
cord-026340-2nf97zvc	151	1	Through	through	IN
cord-026340-2nf97zvc	151	2	bioinformatics	bioinformatics	NN
cord-026340-2nf97zvc	151	3	tool	tool	NN
cord-026340-2nf97zvc	151	4	,	,	,
cord-026340-2nf97zvc	151	5	researchers	researcher	NNS
cord-026340-2nf97zvc	151	6	have	have	VBP
cord-026340-2nf97zvc	151	7	identified	identify	VBN
cord-026340-2nf97zvc	151	8	the	the	DT
cord-026340-2nf97zvc	151	9	presence	presence	NN
cord-026340-2nf97zvc	151	10	of	of	IN
cord-026340-2nf97zvc	151	11	a	a	DT
cord-026340-2nf97zvc	151	12	proline	proline	NN
cord-026340-2nf97zvc	151	13	residue	residue	NN
cord-026340-2nf97zvc	151	14	in	in	IN
cord-026340-2nf97zvc	151	15	the	the	DT
cord-026340-2nf97zvc	151	16	cleavage	cleavage	NN
cord-026340-2nf97zvc	151	17	site	site	NN
cord-026340-2nf97zvc	151	18	and	and	CC
cord-026340-2nf97zvc	151	19	so	so	RB
cord-026340-2nf97zvc	151	20	the	the	DT
cord-026340-2nf97zvc	151	21	inserted	insert	VBN
cord-026340-2nf97zvc	151	22	sequence	sequence	NN
cord-026340-2nf97zvc	151	23	is	be	VBZ
cord-026340-2nf97zvc	151	24	"	"	``
cord-026340-2nf97zvc	151	25	PRRA	PRRA	NNP
cord-026340-2nf97zvc	151	26	"	"	''
cord-026340-2nf97zvc	151	27	.	.	.
cord-026340-2nf97zvc	152	1	Presence	presence	NN
cord-026340-2nf97zvc	152	2	of	of	IN
cord-026340-2nf97zvc	152	3	proline	proline	NN
cord-026340-2nf97zvc	152	4	is	be	VBZ
cord-026340-2nf97zvc	152	5	predicted	predict	VBN
cord-026340-2nf97zvc	152	6	to	to	TO
cord-026340-2nf97zvc	152	7	cause	cause	VB
cord-026340-2nf97zvc	152	8	addition	addition	NN
cord-026340-2nf97zvc	152	9	of	of	IN
cord-026340-2nf97zvc	152	10	O	o	NN
cord-026340-2nf97zvc	152	11	-	-	HYPH
cord-026340-2nf97zvc	152	12	linked	link	VBN
cord-026340-2nf97zvc	152	13	glycans	glycan	NNS
cord-026340-2nf97zvc	152	14	to	to	IN
cord-026340-2nf97zvc	152	15	S673	S673	NNP
cord-026340-2nf97zvc	152	16	,	,	,
cord-026340-2nf97zvc	152	17	T678	t678	CC
cord-026340-2nf97zvc	152	18	and	and	CC
cord-026340-2nf97zvc	152	19	S686	S686	NNPS
cord-026340-2nf97zvc	152	20	that	that	IN
cord-026340-2nf97zvc	152	21	margin	margin	NN
cord-026340-2nf97zvc	152	22	the	the	DT
cord-026340-2nf97zvc	152	23	cleavage	cleavage	NN
cord-026340-2nf97zvc	152	24	site	site	NN
cord-026340-2nf97zvc	152	25	and	and	CC
cord-026340-2nf97zvc	152	26	produce	produce	VB
cord-026340-2nf97zvc	152	27	a	a	DT
cord-026340-2nf97zvc	152	28	mucin	mucin	NN
cord-026340-2nf97zvc	152	29	-	-	HYPH
cord-026340-2nf97zvc	152	30	like	like	JJ
cord-026340-2nf97zvc	152	31	domain	domain	NN
cord-026340-2nf97zvc	152	32	that	that	WDT
cord-026340-2nf97zvc	152	33	can	can	MD
cord-026340-2nf97zvc	152	34	shield	shield	VB
cord-026340-2nf97zvc	152	35	epitope	epitope	NN
cord-026340-2nf97zvc	152	36	or	or	CC
cord-026340-2nf97zvc	152	37	key	key	JJ
cord-026340-2nf97zvc	152	38	residues	residue	NNS
cord-026340-2nf97zvc	152	39	of	of	IN
cord-026340-2nf97zvc	152	40	SARS	SARS	NNP
cord-026340-2nf97zvc	152	41	-	-	HYPH
cord-026340-2nf97zvc	152	42	CoV2	cov2	NN
cord-026340-2nf97zvc	152	43	spike	spike	NN
cord-026340-2nf97zvc	152	44	protein	protein	NN
cord-026340-2nf97zvc	152	45	(	(	-LRB-
cord-026340-2nf97zvc	152	46	Andersen	Andersen	NNP
cord-026340-2nf97zvc	152	47	et	et	NNP
cord-026340-2nf97zvc	152	48	al	al	NNP
cord-026340-2nf97zvc	152	49	.	.	NNP
cord-026340-2nf97zvc	152	50	2020	2020	CD
cord-026340-2nf97zvc	152	51	)	)	-RRB-
cord-026340-2nf97zvc	152	52	.	.	.
cord-026340-2nf97zvc	153	1	These	these	DT
cord-026340-2nf97zvc	153	2	observations	observation	NNS
cord-026340-2nf97zvc	153	3	reinforce	reinforce	VBP
cord-026340-2nf97zvc	153	4	the	the	DT
cord-026340-2nf97zvc	153	5	fact	fact	NN
cord-026340-2nf97zvc	153	6	that	that	IN
cord-026340-2nf97zvc	153	7	SARS	SARS	NNP
cord-026340-2nf97zvc	153	8	-	-	HYPH
cord-026340-2nf97zvc	153	9	CoV2	CoV2	NNP
cord-026340-2nf97zvc	153	10	has	have	VBZ
cord-026340-2nf97zvc	153	11	been	be	VBN
cord-026340-2nf97zvc	153	12	optimized	optimize	VBN
cord-026340-2nf97zvc	153	13	for	for	IN
cord-026340-2nf97zvc	153	14	ACE	ace	NN
cord-026340-2nf97zvc	153	15	,	,	,
cord-026340-2nf97zvc	153	16	but	but	CC
cord-026340-2nf97zvc	153	17	the	the	DT
cord-026340-2nf97zvc	153	18	increased	increase	VBN
cord-026340-2nf97zvc	153	19	virulence	virulence	NN
cord-026340-2nf97zvc	153	20	in	in	IN
cord-026340-2nf97zvc	153	21	some	some	DT
cord-026340-2nf97zvc	153	22	humans	human	NNS
cord-026340-2nf97zvc	153	23	is	be	VBZ
cord-026340-2nf97zvc	153	24	not	not	RB
cord-026340-2nf97zvc	153	25	clear	clear	JJ
cord-026340-2nf97zvc	153	26	.	.	.
cord-026340-2nf97zvc	154	1	Previously	previously	RB
cord-026340-2nf97zvc	154	2	it	-PRON-	PRP
cord-026340-2nf97zvc	154	3	has	have	VBZ
cord-026340-2nf97zvc	154	4	been	be	VBN
cord-026340-2nf97zvc	154	5	shown	show	VBN
cord-026340-2nf97zvc	154	6	that	that	IN
cord-026340-2nf97zvc	154	7	in	in	IN
cord-026340-2nf97zvc	154	8	Avian	avian	JJ
cord-026340-2nf97zvc	154	9	influenza	influenza	NN
cord-026340-2nf97zvc	154	10	,	,	,
cord-026340-2nf97zvc	154	11	the	the	DT
cord-026340-2nf97zvc	154	12	speedy	speedy	JJ
cord-026340-2nf97zvc	154	13	replication	replication	NN
cord-026340-2nf97zvc	154	14	and	and	CC
cord-026340-2nf97zvc	154	15	transmission	transmission	NN
cord-026340-2nf97zvc	154	16	of	of	IN
cord-026340-2nf97zvc	154	17	virus	virus	NN
cord-026340-2nf97zvc	154	18	in	in	IN
cord-026340-2nf97zvc	154	19	high	high	JJ
cord-026340-2nf97zvc	154	20	population	population	NN
cord-026340-2nf97zvc	154	21	of	of	IN
cord-026340-2nf97zvc	154	22	chicken	chicken	NN
cord-026340-2nf97zvc	154	23	'	'	''
cord-026340-2nf97zvc	154	24	selects	select	VBZ
cord-026340-2nf97zvc	154	25	'	'	''
cord-026340-2nf97zvc	154	26	for	for	IN
cord-026340-2nf97zvc	154	27	attainment	attainment	NN
cord-026340-2nf97zvc	154	28	of	of	IN
cord-026340-2nf97zvc	154	29	polybasic	polybasic	JJ
cord-026340-2nf97zvc	154	30	cleavage	cleavage	NN
cord-026340-2nf97zvc	154	31	sites	site	NNS
cord-026340-2nf97zvc	154	32	in	in	IN
cord-026340-2nf97zvc	154	33	a	a	DT
cord-026340-2nf97zvc	154	34	protein	protein	NN
cord-026340-2nf97zvc	154	35	called	call	VBN
cord-026340-2nf97zvc	154	36	hemagglutinin	hemagglutinin	NN
cord-026340-2nf97zvc	154	37	or	or	CC
cord-026340-2nf97zvc	154	38	HA	HA	NNP
cord-026340-2nf97zvc	154	39	(	(	-LRB-
cord-026340-2nf97zvc	154	40	immunodominant	immunodominant	JJ
cord-026340-2nf97zvc	154	41	viral	viral	JJ
cord-026340-2nf97zvc	154	42	antigen	antigen	NN
cord-026340-2nf97zvc	154	43	of	of	IN
cord-026340-2nf97zvc	154	44	H5N1	H5N1	NNP
cord-026340-2nf97zvc	154	45	virus	virus	NN
cord-026340-2nf97zvc	154	46	)	)	-RRB-
cord-026340-2nf97zvc	154	47	.	.	.
cord-026340-2nf97zvc	155	1	Such	such	JJ
cord-026340-2nf97zvc	155	2	acquirement	acquirement	NN
cord-026340-2nf97zvc	155	3	of	of	IN
cord-026340-2nf97zvc	155	4	polybasic	polybasic	JJ
cord-026340-2nf97zvc	155	5	cleavage	cleavage	NN
cord-026340-2nf97zvc	155	6	sites	site	NNS
cord-026340-2nf97zvc	155	7	in	in	IN
cord-026340-2nf97zvc	155	8	hemagglutinin	hemagglutinin	NN
cord-026340-2nf97zvc	155	9	(	(	-LRB-
cord-026340-2nf97zvc	155	10	insertion	insertion	NN
cord-026340-2nf97zvc	155	11	or	or	CC
cord-026340-2nf97zvc	155	12	recombination	recombination	NN
cord-026340-2nf97zvc	155	13	)	)	-RRB-
cord-026340-2nf97zvc	155	14	has	have	VBZ
cord-026340-2nf97zvc	155	15	been	be	VBN
cord-026340-2nf97zvc	155	16	observed	observe	VBN
cord-026340-2nf97zvc	155	17	to	to	TO
cord-026340-2nf97zvc	155	18	convert	convert	VB
cord-026340-2nf97zvc	155	19	low	low	JJ
cord-026340-2nf97zvc	155	20	pathogenic	pathogenic	JJ
cord-026340-2nf97zvc	155	21	viruses	virus	NNS
cord-026340-2nf97zvc	155	22	to	to	IN
cord-026340-2nf97zvc	155	23	very	very	RB
cord-026340-2nf97zvc	155	24	high	high	JJ
cord-026340-2nf97zvc	155	25	pathogenic	pathogenic	JJ
cord-026340-2nf97zvc	155	26	ones	one	NNS
cord-026340-2nf97zvc	156	1	(	(	-LRB-
cord-026340-2nf97zvc	156	2	Andersen	Andersen	NNP
cord-026340-2nf97zvc	156	3	et	et	NNP
cord-026340-2nf97zvc	156	4	al	al	NNP
cord-026340-2nf97zvc	156	5	.	.	NNP
cord-026340-2nf97zvc	156	6	2020	2020	CD
cord-026340-2nf97zvc	156	7	)	)	-RRB-
cord-026340-2nf97zvc	156	8	.	.	.
cord-026340-2nf97zvc	157	1	HA	HA	NNP
cord-026340-2nf97zvc	157	2	has	have	VBZ
cord-026340-2nf97zvc	157	3	a	a	DT
cord-026340-2nf97zvc	157	4	similar	similar	JJ
cord-026340-2nf97zvc	157	5	function	function	NN
cord-026340-2nf97zvc	157	6	with	with	IN
cord-026340-2nf97zvc	157	7	the	the	DT
cord-026340-2nf97zvc	157	8	spike	spike	NN
cord-026340-2nf97zvc	157	9	protein	protein	NN
cord-026340-2nf97zvc	157	10	of	of	IN
cord-026340-2nf97zvc	157	11	SARS	SARS	NNP
cord-026340-2nf97zvc	157	12	-	-	HYPH
cord-026340-2nf97zvc	157	13	CoV2	CoV2	NNP
cord-026340-2nf97zvc	157	14	but	but	CC
cord-026340-2nf97zvc	157	15	whether	whether	IN
cord-026340-2nf97zvc	157	16	a	a	DT
cord-026340-2nf97zvc	157	17	similar	similar	JJ
cord-026340-2nf97zvc	157	18	mechanism	mechanism	NN
cord-026340-2nf97zvc	157	19	is	be	VBZ
cord-026340-2nf97zvc	157	20	operating	operate	VBG
cord-026340-2nf97zvc	157	21	in	in	IN
cord-026340-2nf97zvc	157	22	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	157	23	needs	need	NNS
cord-026340-2nf97zvc	157	24	to	to	TO
cord-026340-2nf97zvc	157	25	be	be	VB
cord-026340-2nf97zvc	157	26	validated	validate	VBN
cord-026340-2nf97zvc	157	27	.	.	.
cord-026340-2nf97zvc	158	1	We	-PRON-	PRP
cord-026340-2nf97zvc	158	2	have	have	VBP
cord-026340-2nf97zvc	158	3	also	also	RB
cord-026340-2nf97zvc	158	4	seen	see	VBN
cord-026340-2nf97zvc	158	5	that	that	IN
cord-026340-2nf97zvc	158	6	for	for	IN
cord-026340-2nf97zvc	158	7	SARS	SARS	NNP
cord-026340-2nf97zvc	158	8	-	-	HYPH
cord-026340-2nf97zvc	158	9	CoV	CoV	NNP
cord-026340-2nf97zvc	158	10	,	,	,
cord-026340-2nf97zvc	158	11	the	the	DT
cord-026340-2nf97zvc	158	12	evolutionary	evolutionary	JJ
cord-026340-2nf97zvc	158	13	starting	starting	NN
cord-026340-2nf97zvc	158	14	point	point	NN
cord-026340-2nf97zvc	158	15	(	(	-LRB-
cord-026340-2nf97zvc	158	16	as	as	IN
cord-026340-2nf97zvc	158	17	evidenced	evidence	VBN
cord-026340-2nf97zvc	158	18	by	by	IN
cord-026340-2nf97zvc	158	19	palm	palm	NN
cord-026340-2nf97zvc	158	20	civets	civet	NNS
cord-026340-2nf97zvc	158	21	)	)	-RRB-
cord-026340-2nf97zvc	158	22	was	be	VBD
cord-026340-2nf97zvc	158	23	a	a	DT
cord-026340-2nf97zvc	158	24	prototype	prototype	NN
cord-026340-2nf97zvc	158	25	virus	virus	NN
cord-026340-2nf97zvc	158	26	group	group	NN
cord-026340-2nf97zvc	158	27	with	with	IN
cord-026340-2nf97zvc	158	28	low	low	JJ
cord-026340-2nf97zvc	158	29	-	-	HYPH
cord-026340-2nf97zvc	158	30	pathogenicity	pathogenicity	NN
cord-026340-2nf97zvc	158	31	with	with	IN
cord-026340-2nf97zvc	158	32	7	7	CD
cord-026340-2nf97zvc	158	33	singlenucleotide	singlenucleotide	NN
cord-026340-2nf97zvc	158	34	variations	variation	NNS
cord-026340-2nf97zvc	158	35	(	(	-LRB-
cord-026340-2nf97zvc	158	36	SNV	SNV	NNP
cord-026340-2nf97zvc	158	37	)	)	-RRB-
cord-026340-2nf97zvc	158	38	which	which	WDT
cord-026340-2nf97zvc	158	39	caused	cause	VBD
cord-026340-2nf97zvc	158	40	6	6	CD
cord-026340-2nf97zvc	158	41	amino	amino	NN
cord-026340-2nf97zvc	158	42	acid	acid	NN
cord-026340-2nf97zvc	158	43	changes	change	NNS
cord-026340-2nf97zvc	158	44	in	in	IN
cord-026340-2nf97zvc	158	45	the	the	DT
cord-026340-2nf97zvc	158	46	S	S	NNP
cord-026340-2nf97zvc	158	47	protein	protein	NN
cord-026340-2nf97zvc	158	48	.	.	.
cord-026340-2nf97zvc	159	1	This	this	DT
cord-026340-2nf97zvc	159	2	group	group	NN
cord-026340-2nf97zvc	159	3	caused	cause	VBD
cord-026340-2nf97zvc	159	4	the	the	DT
cord-026340-2nf97zvc	159	5	early	early	JJ
cord-026340-2nf97zvc	159	6	phase	phase	NN
cord-026340-2nf97zvc	159	7	of	of	IN
cord-026340-2nf97zvc	159	8	the	the	DT
cord-026340-2nf97zvc	159	9	2002	2002	CD
cord-026340-2nf97zvc	159	10	-	-	SYM
cord-026340-2nf97zvc	159	11	2003	2003	CD
cord-026340-2nf97zvc	159	12	epidemic	epidemic	NN
cord-026340-2nf97zvc	159	13	.	.	.
cord-026340-2nf97zvc	160	1	Later	later	RB
cord-026340-2nf97zvc	160	2	,	,	,
cord-026340-2nf97zvc	160	3	further	further	JJ
cord-026340-2nf97zvc	160	4	changes	change	NNS
cord-026340-2nf97zvc	160	5	,	,	,
cord-026340-2nf97zvc	160	6	i.e.	i.e.	FW
cord-026340-2nf97zvc	160	7	,	,	,
cord-026340-2nf97zvc	160	8	14	14	CD
cord-026340-2nf97zvc	160	9	SNVs	snv	NNS
cord-026340-2nf97zvc	160	10	caused	cause	VBD
cord-026340-2nf97zvc	160	11	11	11	CD
cord-026340-2nf97zvc	160	12	amino	amino	NN
cord-026340-2nf97zvc	160	13	acid	acid	NN
cord-026340-2nf97zvc	160	14	residue	residue	NN
cord-026340-2nf97zvc	160	15	changes	change	NNS
cord-026340-2nf97zvc	160	16	that	that	WDT
cord-026340-2nf97zvc	160	17	produced	produce	VBD
cord-026340-2nf97zvc	160	18	a	a	DT
cord-026340-2nf97zvc	160	19	"	"	``
cord-026340-2nf97zvc	160	20	highly	highly	RB
cord-026340-2nf97zvc	160	21	virulent	virulent	JJ
cord-026340-2nf97zvc	160	22	group	group	NN
cord-026340-2nf97zvc	160	23	"	"	''
cord-026340-2nf97zvc	160	24	which	which	WDT
cord-026340-2nf97zvc	160	25	caused	cause	VBD
cord-026340-2nf97zvc	160	26	the	the	DT
cord-026340-2nf97zvc	160	27	middle	middle	JJ
cord-026340-2nf97zvc	160	28	phase	phase	NN
cord-026340-2nf97zvc	160	29	of	of	IN
cord-026340-2nf97zvc	160	30	the	the	DT
cord-026340-2nf97zvc	160	31	epidemic	epidemic	NN
cord-026340-2nf97zvc	160	32	of	of	IN
cord-026340-2nf97zvc	160	33	2003	2003	CD
cord-026340-2nf97zvc	160	34	.	.	.
cord-026340-2nf97zvc	161	1	Thereafter	thereafter	RB
cord-026340-2nf97zvc	161	2	,	,	,
cord-026340-2nf97zvc	161	3	6	6	CD
cord-026340-2nf97zvc	161	4	SNVs	snv	NNS
cord-026340-2nf97zvc	161	5	caused	cause	VBD
cord-026340-2nf97zvc	161	6	four	four	CD
cord-026340-2nf97zvc	161	7	amino	amino	NN
cord-026340-2nf97zvc	161	8	acid	acid	NN
cord-026340-2nf97zvc	161	9	changes	change	NNS
cord-026340-2nf97zvc	161	10	and	and	CC
cord-026340-2nf97zvc	161	11	brought	bring	VBD
cord-026340-2nf97zvc	161	12	about	about	RP
cord-026340-2nf97zvc	161	13	a	a	DT
cord-026340-2nf97zvc	161	14	group	group	NN
cord-026340-2nf97zvc	161	15	responsible	responsible	JJ
cord-026340-2nf97zvc	161	16	for	for	IN
cord-026340-2nf97zvc	161	17	the	the	DT
cord-026340-2nf97zvc	161	18	late	late	JJ
cord-026340-2nf97zvc	161	19	phase	phase	NN
cord-026340-2nf97zvc	161	20	and	and	CC
cord-026340-2nf97zvc	161	21	the	the	DT
cord-026340-2nf97zvc	161	22	global	global	JJ
cord-026340-2nf97zvc	161	23	epidemic	epidemic	NN
cord-026340-2nf97zvc	161	24	.	.	.
cord-026340-2nf97zvc	162	1	The	the	DT
cord-026340-2nf97zvc	162	2	neutral	neutral	JJ
cord-026340-2nf97zvc	162	3	mutation	mutation	NN
cord-026340-2nf97zvc	162	4	rate	rate	NN
cord-026340-2nf97zvc	162	5	of	of	IN
cord-026340-2nf97zvc	162	6	this	this	DT
cord-026340-2nf97zvc	162	7	virus	virus	NN
cord-026340-2nf97zvc	162	8	during	during	IN
cord-026340-2nf97zvc	162	9	2003	2003	CD
cord-026340-2nf97zvc	162	10	was	be	VBD
cord-026340-2nf97zvc	162	11	almost	almost	RB
cord-026340-2nf97zvc	162	12	constant	constant	JJ
cord-026340-2nf97zvc	162	13	,	,	,
cord-026340-2nf97zvc	162	14	at	at	IN
cord-026340-2nf97zvc	162	15	around	around	IN
cord-026340-2nf97zvc	162	16	8	8	CD
cord-026340-2nf97zvc	162	17	×	×	CD
cord-026340-2nf97zvc	162	18	10	10	CD
cord-026340-2nf97zvc	162	19	−6	−6	NNS
cord-026340-2nf97zvc	162	20	nt	nt	NNP
cord-026340-2nf97zvc	162	21	−1	−1	NNP
cord-026340-2nf97zvc	162	22	day	day	NN
cord-026340-2nf97zvc	162	23	−1	−1	NNP
cord-026340-2nf97zvc	162	24	,	,	,
cord-026340-2nf97zvc	162	25	which	which	WDT
cord-026340-2nf97zvc	162	26	was	be	VBD
cord-026340-2nf97zvc	162	27	the	the	DT
cord-026340-2nf97zvc	162	28	same	same	JJ
cord-026340-2nf97zvc	162	29	with	with	IN
cord-026340-2nf97zvc	162	30	the	the	DT
cord-026340-2nf97zvc	162	31	most	most	RBS
cord-026340-2nf97zvc	162	32	recognized	recognize	VBN
cord-026340-2nf97zvc	162	33	RNA	RNA	NNP
cord-026340-2nf97zvc	162	34	viruses	virus	NNS
cord-026340-2nf97zvc	162	35	.	.	.
cord-026340-2nf97zvc	163	1	Afterwards	afterwards	RB
cord-026340-2nf97zvc	163	2	,	,	,
cord-026340-2nf97zvc	163	3	a	a	DT
cord-026340-2nf97zvc	163	4	second	second	JJ
cord-026340-2nf97zvc	163	5	interspecies	interspecie	NNS
cord-026340-2nf97zvc	163	6	jump	jump	NN
cord-026340-2nf97zvc	163	7	recorded	record	VBN
cord-026340-2nf97zvc	163	8	in	in	IN
cord-026340-2nf97zvc	163	9	late	late	JJ
cord-026340-2nf97zvc	163	10	2003	2003	CD
cord-026340-2nf97zvc	163	11	to	to	IN
cord-026340-2nf97zvc	163	12	early	early	JJ
cord-026340-2nf97zvc	163	13	2004	2004	CD
cord-026340-2nf97zvc	163	14	,	,	,
cord-026340-2nf97zvc	163	15	caused	cause	VBN
cord-026340-2nf97zvc	163	16	resurgence	resurgence	NN
cord-026340-2nf97zvc	163	17	SARS	SARS	NNP
cord-026340-2nf97zvc	163	18	in	in	IN
cord-026340-2nf97zvc	163	19	China	China	NNP
cord-026340-2nf97zvc	163	20	.	.	.
cord-026340-2nf97zvc	164	1	This	this	DT
cord-026340-2nf97zvc	164	2	was	be	VBD
cord-026340-2nf97zvc	164	3	,	,	,
cord-026340-2nf97zvc	164	4	however	however	RB
cord-026340-2nf97zvc	164	5	,	,	,
cord-026340-2nf97zvc	164	6	thought	think	VBD
cord-026340-2nf97zvc	164	7	to	to	TO
cord-026340-2nf97zvc	164	8	be	be	VB
cord-026340-2nf97zvc	164	9	an	an	DT
cord-026340-2nf97zvc	164	10	independent	independent	JJ
cord-026340-2nf97zvc	164	11	interspecies	interspecie	NNS
cord-026340-2nf97zvc	164	12	transmission	transmission	NN
cord-026340-2nf97zvc	164	13	event	event	NN
cord-026340-2nf97zvc	164	14	,	,	,
cord-026340-2nf97zvc	164	15	instead	instead	RB
cord-026340-2nf97zvc	164	16	of	of	IN
cord-026340-2nf97zvc	164	17	residual	residual	JJ
cord-026340-2nf97zvc	164	18	cases	case	NNS
cord-026340-2nf97zvc	164	19	of	of	IN
cord-026340-2nf97zvc	164	20	the	the	DT
cord-026340-2nf97zvc	164	21	major	major	JJ
cord-026340-2nf97zvc	164	22	epidemic	epidemic	NN
cord-026340-2nf97zvc	164	23	because	because	IN
cord-026340-2nf97zvc	164	24	the	the	DT
cord-026340-2nf97zvc	164	25	virus	virus	NN
cord-026340-2nf97zvc	164	26	had	have	VBD
cord-026340-2nf97zvc	164	27	lower	low	JJR
cord-026340-2nf97zvc	164	28	affinity	affinity	NN
cord-026340-2nf97zvc	164	29	of	of	IN
cord-026340-2nf97zvc	164	30	virus	virus	NN
cord-026340-2nf97zvc	164	31	for	for	IN
cord-026340-2nf97zvc	164	32	human	human	JJ
cord-026340-2nf97zvc	164	33	ACE2	ACE2	NNP
cord-026340-2nf97zvc	165	1	(	(	-LRB-
cord-026340-2nf97zvc	165	2	Cheng	Cheng	NNP
cord-026340-2nf97zvc	165	3	et	et	NNP
cord-026340-2nf97zvc	165	4	al	al	NNP
cord-026340-2nf97zvc	165	5	.	.	.
cord-026340-2nf97zvc	166	1	2007	2007	CD
cord-026340-2nf97zvc	166	2	;	;	:
cord-026340-2nf97zvc	166	3	Kan	Kan	NNP
cord-026340-2nf97zvc	166	4	et	et	NNP
cord-026340-2nf97zvc	166	5	al	al	NNP
cord-026340-2nf97zvc	166	6	.	.	.
cord-026340-2nf97zvc	167	1	2005	2005	CD
cord-026340-2nf97zvc	167	2	;	;	:
cord-026340-2nf97zvc	167	3	Zhang	Zhang	NNP
cord-026340-2nf97zvc	167	4	et	et	NNP
cord-026340-2nf97zvc	167	5	al	al	NNP
cord-026340-2nf97zvc	167	6	.	.	NNP
cord-026340-2nf97zvc	167	7	2020	2020	CD
cord-026340-2nf97zvc	167	8	)	)	-RRB-
cord-026340-2nf97zvc	167	9	.	.	.
cord-026340-2nf97zvc	168	1	Such	such	JJ
cord-026340-2nf97zvc	168	2	mutations	mutation	NNS
cord-026340-2nf97zvc	168	3	may	may	MD
cord-026340-2nf97zvc	168	4	be	be	VB
cord-026340-2nf97zvc	168	5	operational	operational	JJ
cord-026340-2nf97zvc	168	6	in	in	IN
cord-026340-2nf97zvc	168	7	the	the	DT
cord-026340-2nf97zvc	168	8	case	case	NN
cord-026340-2nf97zvc	168	9	of	of	IN
cord-026340-2nf97zvc	168	10	SARS	SARS	NNP
cord-026340-2nf97zvc	168	11	-	-	HYPH
cord-026340-2nf97zvc	168	12	CoV2	CoV2	NNP
cord-026340-2nf97zvc	168	13	virus	virus	NN
cord-026340-2nf97zvc	168	14	as	as	RB
cord-026340-2nf97zvc	168	15	well	well	RB
cord-026340-2nf97zvc	168	16	and	and	CC
cord-026340-2nf97zvc	168	17	,	,	,
cord-026340-2nf97zvc	168	18	hence	hence	RB
cord-026340-2nf97zvc	168	19	,	,	,
cord-026340-2nf97zvc	168	20	the	the	DT
cord-026340-2nf97zvc	168	21	differences	difference	NNS
cord-026340-2nf97zvc	168	22	in	in	IN
cord-026340-2nf97zvc	168	23	severity	severity	NN
cord-026340-2nf97zvc	168	24	we	-PRON-	PRP
cord-026340-2nf97zvc	168	25	seen	see	VBD
cord-026340-2nf97zvc	168	26	in	in	IN
cord-026340-2nf97zvc	168	27	Italy	Italy	NNP
cord-026340-2nf97zvc	168	28	,	,	,
cord-026340-2nf97zvc	168	29	China	China	NNP
cord-026340-2nf97zvc	168	30	,	,	,
cord-026340-2nf97zvc	168	31	United	United	NNP
cord-026340-2nf97zvc	168	32	Kingdom	Kingdom	NNP
cord-026340-2nf97zvc	168	33	,	,	,
cord-026340-2nf97zvc	168	34	Japan	Japan	NNP
cord-026340-2nf97zvc	168	35	,	,	,
cord-026340-2nf97zvc	168	36	USA	USA	NNP
cord-026340-2nf97zvc	168	37	and	and	CC
cord-026340-2nf97zvc	168	38	India	India	NNP
cord-026340-2nf97zvc	168	39	.	.	.
cord-026340-2nf97zvc	169	1	What	what	WP
cord-026340-2nf97zvc	169	2	governs	govern	VBZ
cord-026340-2nf97zvc	169	3	the	the	DT
cord-026340-2nf97zvc	169	4	affinity	affinity	NN
cord-026340-2nf97zvc	169	5	of	of	IN
cord-026340-2nf97zvc	169	6	a	a	DT
cord-026340-2nf97zvc	169	7	virus	virus	NN
cord-026340-2nf97zvc	169	8	towards	towards	IN
cord-026340-2nf97zvc	169	9	the	the	DT
cord-026340-2nf97zvc	169	10	human	human	JJ
cord-026340-2nf97zvc	169	11	host	host	NN
cord-026340-2nf97zvc	169	12	cell	cell	NN
cord-026340-2nf97zvc	169	13	?	?	.
cord-026340-2nf97zvc	170	1	As	as	IN
cord-026340-2nf97zvc	170	2	for	for	IN
cord-026340-2nf97zvc	170	3	the	the	DT
cord-026340-2nf97zvc	170	4	case	case	NN
cord-026340-2nf97zvc	170	5	of	of	IN
cord-026340-2nf97zvc	170	6	SARS	SARS	NNP
cord-026340-2nf97zvc	170	7	-	-	HYPH
cord-026340-2nf97zvc	170	8	CoV	CoV	NNP
cord-026340-2nf97zvc	170	9	,	,	,
cord-026340-2nf97zvc	170	10	it	-PRON-	PRP
cord-026340-2nf97zvc	170	11	was	be	VBD
cord-026340-2nf97zvc	170	12	shown	show	VBN
cord-026340-2nf97zvc	170	13	that	that	IN
cord-026340-2nf97zvc	170	14	the	the	DT
cord-026340-2nf97zvc	170	15	binding	bind	VBG
cord-026340-2nf97zvc	170	16	specificity	specificity	NN
cord-026340-2nf97zvc	170	17	of	of	IN
cord-026340-2nf97zvc	170	18	virus	virus	NN
cord-026340-2nf97zvc	170	19	to	to	TO
cord-026340-2nf97zvc	170	20	host	host	VB
cord-026340-2nf97zvc	170	21	cell	cell	NN
cord-026340-2nf97zvc	170	22	was	be	VBD
cord-026340-2nf97zvc	170	23	due	due	JJ
cord-026340-2nf97zvc	170	24	to	to	IN
cord-026340-2nf97zvc	170	25	3	3	CD
cord-026340-2nf97zvc	170	26	prime	prime	JJ
cord-026340-2nf97zvc	170	27	amino	amino	NN
cord-026340-2nf97zvc	170	28	acid	acid	NN
cord-026340-2nf97zvc	170	29	residues	residue	NNS
cord-026340-2nf97zvc	170	30	in	in	IN
cord-026340-2nf97zvc	170	31	S1	s1	NN
cord-026340-2nf97zvc	170	32	protein	protein	NN
cord-026340-2nf97zvc	170	33	at	at	IN
cord-026340-2nf97zvc	170	34	positions	position	NNS
cord-026340-2nf97zvc	170	35	360	360	CD
cord-026340-2nf97zvc	170	36	,	,	,
cord-026340-2nf97zvc	170	37	479	479	CD
cord-026340-2nf97zvc	170	38	,	,	,
cord-026340-2nf97zvc	170	39	and	and	CC
cord-026340-2nf97zvc	170	40	487	487	CD
cord-026340-2nf97zvc	170	41	.	.	.
cord-026340-2nf97zvc	171	1	Interestingly	interestingly	RB
cord-026340-2nf97zvc	171	2	,	,	,
cord-026340-2nf97zvc	171	3	the	the	DT
cord-026340-2nf97zvc	171	4	patient	patient	NN
cord-026340-2nf97zvc	171	5	samples	sample	NNS
cord-026340-2nf97zvc	171	6	in	in	IN
cord-026340-2nf97zvc	171	7	the	the	DT
cord-026340-2nf97zvc	171	8	2003	2003	CD
cord-026340-2nf97zvc	171	9	epidemic	epidemic	NN
cord-026340-2nf97zvc	171	10	had	have	VBD
cord-026340-2nf97zvc	171	11	N479	N479	NNP
cord-026340-2nf97zvc	171	12	and	and	CC
cord-026340-2nf97zvc	171	13	T487	T487	NNPS
cord-026340-2nf97zvc	171	14	in	in	IN
cord-026340-2nf97zvc	171	15	their	-PRON-	PRP$
cord-026340-2nf97zvc	171	16	S	s	NN
cord-026340-2nf97zvc	171	17	protein	protein	NN
cord-026340-2nf97zvc	171	18	,	,	,
cord-026340-2nf97zvc	171	19	while	while	IN
cord-026340-2nf97zvc	171	20	most	most	JJS
cord-026340-2nf97zvc	171	21	civet	civet	NN
cord-026340-2nf97zvc	171	22	samples	sample	NNS
cord-026340-2nf97zvc	171	23	had	have	VBD
cord-026340-2nf97zvc	171	24	K	K	NNP
cord-026340-2nf97zvc	171	25	/	/	SYM
cord-026340-2nf97zvc	171	26	R479	R479	NNPS
cord-026340-2nf97zvc	171	27	and	and	CC
cord-026340-2nf97zvc	171	28	S487	S487	NNP
cord-026340-2nf97zvc	171	29	,	,	,
cord-026340-2nf97zvc	171	30	which	which	WDT
cord-026340-2nf97zvc	171	31	is	be	VBZ
cord-026340-2nf97zvc	171	32	a	a	DT
cord-026340-2nf97zvc	171	33	combination	combination	NN
cord-026340-2nf97zvc	171	34	that	that	WDT
cord-026340-2nf97zvc	171	35	reduces	reduce	VBZ
cord-026340-2nf97zvc	171	36	the	the	DT
cord-026340-2nf97zvc	171	37	affinity	affinity	NN
cord-026340-2nf97zvc	171	38	of	of	IN
cord-026340-2nf97zvc	171	39	virus	virus	NN
cord-026340-2nf97zvc	171	40	for	for	IN
cord-026340-2nf97zvc	171	41	receptor	receptor	NN
cord-026340-2nf97zvc	171	42	.	.	.
cord-026340-2nf97zvc	172	1	At	at	IN
cord-026340-2nf97zvc	172	2	the	the	DT
cord-026340-2nf97zvc	172	3	later	later	JJ
cord-026340-2nf97zvc	172	4	stages	stage	NNS
cord-026340-2nf97zvc	172	5	of	of	IN
cord-026340-2nf97zvc	172	6	the	the	DT
cord-026340-2nf97zvc	172	7	epidemic	epidemic	NN
cord-026340-2nf97zvc	172	8	(	(	-LRB-
cord-026340-2nf97zvc	172	9	2003	2003	CD
cord-026340-2nf97zvc	172	10	)	)	-RRB-
cord-026340-2nf97zvc	172	11	(	(	-LRB-
cord-026340-2nf97zvc	172	12	2004	2004	CD
cord-026340-2nf97zvc	172	13	)	)	-RRB-
cord-026340-2nf97zvc	172	14	,	,	,
cord-026340-2nf97zvc	172	15	both	both	CC
cord-026340-2nf97zvc	172	16	the	the	DT
cord-026340-2nf97zvc	172	17	samples	sample	NNS
cord-026340-2nf97zvc	172	18	from	from	IN
cord-026340-2nf97zvc	172	19	humans	human	NNS
cord-026340-2nf97zvc	172	20	and	and	CC
cord-026340-2nf97zvc	172	21	civet	civet	NN
cord-026340-2nf97zvc	172	22	showed	show	VBD
cord-026340-2nf97zvc	172	23	the	the	DT
cord-026340-2nf97zvc	172	24	presence	presence	NN
cord-026340-2nf97zvc	172	25	of	of	IN
cord-026340-2nf97zvc	172	26	N479	N479	NNP
cord-026340-2nf97zvc	172	27	and	and	CC
cord-026340-2nf97zvc	172	28	S487	S487	NNP
cord-026340-2nf97zvc	172	29	,	,	,
cord-026340-2nf97zvc	172	30	signifying	signify	VBG
cord-026340-2nf97zvc	172	31	an	an	DT
cord-026340-2nf97zvc	172	32	intermediate	intermediate	JJ
cord-026340-2nf97zvc	172	33	stage	stage	NN
cord-026340-2nf97zvc	172	34	of	of	IN
cord-026340-2nf97zvc	172	35	mutation	mutation	NN
cord-026340-2nf97zvc	172	36	of	of	IN
cord-026340-2nf97zvc	172	37	the	the	DT
cord-026340-2nf97zvc	172	38	S	S	NNP
cord-026340-2nf97zvc	172	39	protein	protein	NN
cord-026340-2nf97zvc	172	40	.	.	.
cord-026340-2nf97zvc	173	1	Additional	additional	JJ
cord-026340-2nf97zvc	173	2	change	change	NN
cord-026340-2nf97zvc	173	3	to	to	IN
cord-026340-2nf97zvc	173	4	the	the	DT
cord-026340-2nf97zvc	173	5	N479	N479	NNP
cord-026340-2nf97zvc	173	6	and	and	CC
cord-026340-2nf97zvc	173	7	T487	T487	NNP
cord-026340-2nf97zvc	173	8	combination	combination	NN
cord-026340-2nf97zvc	173	9	is	be	VBZ
cord-026340-2nf97zvc	173	10	believed	believe	VBN
cord-026340-2nf97zvc	173	11	have	have	VBP
cord-026340-2nf97zvc	173	12	allowed	allow	VBN
cord-026340-2nf97zvc	173	13	competent	competent	JJ
cord-026340-2nf97zvc	173	14	human	human	NN
cord-026340-2nf97zvc	173	15	-	-	HYPH
cord-026340-2nf97zvc	173	16	to	to	IN
cord-026340-2nf97zvc	173	17	-	-	HYPH
cord-026340-2nf97zvc	173	18	human	human	JJ
cord-026340-2nf97zvc	173	19	transmission	transmission	NN
cord-026340-2nf97zvc	173	20	.	.	.
cord-026340-2nf97zvc	174	1	A	a	DT
cord-026340-2nf97zvc	174	2	different	different	JJ
cord-026340-2nf97zvc	174	3	set	set	NN
cord-026340-2nf97zvc	174	4	of	of	IN
cord-026340-2nf97zvc	174	5	studies	study	NNS
cord-026340-2nf97zvc	174	6	conducted	conduct	VBN
cord-026340-2nf97zvc	174	7	using	use	VBG
cord-026340-2nf97zvc	174	8	samples	sample	NNS
cord-026340-2nf97zvc	174	9	isolated	isolate	VBN
cord-026340-2nf97zvc	174	10	from	from	IN
cord-026340-2nf97zvc	174	11	game	game	NN
cord-026340-2nf97zvc	174	12	animals	animal	NNS
cord-026340-2nf97zvc	174	13	(	(	-LRB-
cord-026340-2nf97zvc	174	14	animals	animal	NNS
cord-026340-2nf97zvc	174	15	hunted	hunt	VBN
cord-026340-2nf97zvc	174	16	for	for	IN
cord-026340-2nf97zvc	174	17	sports	sport	NNS
cord-026340-2nf97zvc	174	18	)	)	-RRB-
cord-026340-2nf97zvc	174	19	from	from	IN
cord-026340-2nf97zvc	174	20	Guangdong	Guangdong	NNP
cord-026340-2nf97zvc	174	21	also	also	RB
cord-026340-2nf97zvc	174	22	showed	show	VBD
cord-026340-2nf97zvc	174	23	high	high	JJ
cord-026340-2nf97zvc	174	24	nucleotide	nucleotide	JJ
cord-026340-2nf97zvc	174	25	similarity	similarity	NN
cord-026340-2nf97zvc	174	26	with	with	IN
cord-026340-2nf97zvc	174	27	SARS	SARS	NNP
cord-026340-2nf97zvc	174	28	-	-	HYPH
cord-026340-2nf97zvc	174	29	CoV.	CoV.	NNP
cord-026340-2nf97zvc	175	1	These	these	DT
cord-026340-2nf97zvc	175	2	exhibited	exhibit	VBD
cord-026340-2nf97zvc	175	3	an	an	DT
cord-026340-2nf97zvc	175	4	insertion	insertion	NN
cord-026340-2nf97zvc	175	5	of	of	IN
cord-026340-2nf97zvc	175	6	29-bp	29-bp	CD
cord-026340-2nf97zvc	175	7	between	between	IN
cord-026340-2nf97zvc	175	8	Orf8a	Orf8a	NNP
cord-026340-2nf97zvc	175	9	and	and	CC
cord-026340-2nf97zvc	175	10	Orf8b	Orf8b	NNP
cord-026340-2nf97zvc	175	11	in	in	IN
cord-026340-2nf97zvc	175	12	animals	animal	NNS
cord-026340-2nf97zvc	175	13	,	,	,
cord-026340-2nf97zvc	175	14	which	which	WDT
cord-026340-2nf97zvc	175	15	was	be	VBD
cord-026340-2nf97zvc	175	16	deleted	delete	VBN
cord-026340-2nf97zvc	175	17	either	either	CC
cord-026340-2nf97zvc	175	18	before	before	IN
cord-026340-2nf97zvc	175	19	or	or	CC
cord-026340-2nf97zvc	175	20	soon	soon	RB
cord-026340-2nf97zvc	175	21	after	after	IN
cord-026340-2nf97zvc	175	22	crossing	cross	VBG
cord-026340-2nf97zvc	175	23	the	the	DT
cord-026340-2nf97zvc	175	24	species	specie	NNS
cord-026340-2nf97zvc	175	25	barrier	barrier	NN
cord-026340-2nf97zvc	175	26	to	to	IN
cord-026340-2nf97zvc	175	27	humans	human	NNS
cord-026340-2nf97zvc	176	1	(	(	-LRB-
cord-026340-2nf97zvc	176	2	Cheng	Cheng	NNP
cord-026340-2nf97zvc	176	3	et	et	NNP
cord-026340-2nf97zvc	176	4	al	al	NNP
cord-026340-2nf97zvc	176	5	.	.	NNP
cord-026340-2nf97zvc	176	6	2007	2007	CD
cord-026340-2nf97zvc	176	7	)	)	-RRB-
cord-026340-2nf97zvc	176	8	.	.	.
cord-026340-2nf97zvc	177	1	We	-PRON-	PRP
cord-026340-2nf97zvc	177	2	are	be	VBP
cord-026340-2nf97zvc	177	3	yet	yet	RB
cord-026340-2nf97zvc	177	4	to	to	TO
cord-026340-2nf97zvc	177	5	figure	figure	VB
cord-026340-2nf97zvc	177	6	out	out	RP
cord-026340-2nf97zvc	177	7	what	what	WP
cord-026340-2nf97zvc	177	8	are	be	VBP
cord-026340-2nf97zvc	177	9	the	the	DT
cord-026340-2nf97zvc	177	10	differences	difference	NNS
cord-026340-2nf97zvc	177	11	in	in	IN
cord-026340-2nf97zvc	177	12	amino	amino	NN
cord-026340-2nf97zvc	177	13	acid	acid	NN
cord-026340-2nf97zvc	177	14	residues	residue	NNS
cord-026340-2nf97zvc	177	15	of	of	IN
cord-026340-2nf97zvc	177	16	SARS	SARS	NNP
cord-026340-2nf97zvc	177	17	-	-	HYPH
cord-026340-2nf97zvc	177	18	CoV2	CoV2	NNP
cord-026340-2nf97zvc	177	19	that	that	WDT
cord-026340-2nf97zvc	177	20	made	make	VBD
cord-026340-2nf97zvc	177	21	it	-PRON-	PRP
cord-026340-2nf97zvc	177	22	effectively	effectively	RB
cord-026340-2nf97zvc	177	23	adhere	adhere	VB
cord-026340-2nf97zvc	177	24	to	to	IN
cord-026340-2nf97zvc	177	25	the	the	DT
cord-026340-2nf97zvc	177	26	ACE	ace	NN
cord-026340-2nf97zvc	177	27	receptors	receptor	NNS
cord-026340-2nf97zvc	177	28	on	on	IN
cord-026340-2nf97zvc	177	29	endothelial	endothelial	JJ
cord-026340-2nf97zvc	177	30	cells	cell	NNS
cord-026340-2nf97zvc	177	31	and	and	CC
cord-026340-2nf97zvc	177	32	lungs	lung	NNS
cord-026340-2nf97zvc	177	33	and	and	CC
cord-026340-2nf97zvc	177	34	other	other	JJ
cord-026340-2nf97zvc	177	35	cells	cell	NNS
cord-026340-2nf97zvc	177	36	of	of	IN
cord-026340-2nf97zvc	177	37	the	the	DT
cord-026340-2nf97zvc	177	38	human	human	JJ
cord-026340-2nf97zvc	177	39	body	body	NN
cord-026340-2nf97zvc	177	40	.	.	.
cord-026340-2nf97zvc	178	1	Today	today	NN
cord-026340-2nf97zvc	178	2	,	,	,
cord-026340-2nf97zvc	178	3	governments	government	NNS
cord-026340-2nf97zvc	178	4	face	face	VBP
cord-026340-2nf97zvc	178	5	a	a	DT
cord-026340-2nf97zvc	178	6	very	very	RB
cord-026340-2nf97zvc	178	7	urgent	urgent	JJ
cord-026340-2nf97zvc	178	8	need	need	NN
cord-026340-2nf97zvc	178	9	for	for	IN
cord-026340-2nf97zvc	178	10	measures	measure	NNS
cord-026340-2nf97zvc	178	11	to	to	TO
cord-026340-2nf97zvc	178	12	tame	tame	VB
cord-026340-2nf97zvc	178	13	of	of	IN
cord-026340-2nf97zvc	178	14	the	the	DT
cord-026340-2nf97zvc	178	15	rapid	rapid	JJ
cord-026340-2nf97zvc	178	16	spread	spread	NN
cord-026340-2nf97zvc	178	17	of	of	IN
cord-026340-2nf97zvc	178	18	SARS	SARS	NNP
cord-026340-2nf97zvc	178	19	-	-	HYPH
cord-026340-2nf97zvc	178	20	CoV2	CoV2	NNP
cord-026340-2nf97zvc	178	21	.	.	.
cord-026340-2nf97zvc	179	1	Hence	hence	RB
cord-026340-2nf97zvc	179	2	,	,	,
cord-026340-2nf97zvc	179	3	clinicians	clinician	NNS
cord-026340-2nf97zvc	179	4	and	and	CC
cord-026340-2nf97zvc	179	5	researchers	researcher	NNS
cord-026340-2nf97zvc	179	6	across	across	IN
cord-026340-2nf97zvc	179	7	the	the	DT
cord-026340-2nf97zvc	179	8	globe	globe	NN
cord-026340-2nf97zvc	179	9	are	be	VBP
cord-026340-2nf97zvc	179	10	actively	actively	RB
cord-026340-2nf97zvc	179	11	engaged	engage	VBN
cord-026340-2nf97zvc	179	12	in	in	IN
cord-026340-2nf97zvc	179	13	identifying	identify	VBG
cord-026340-2nf97zvc	179	14	effective	effective	JJ
cord-026340-2nf97zvc	179	15	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	179	16	strategies	strategy	NNS
cord-026340-2nf97zvc	179	17	to	to	TO
cord-026340-2nf97zvc	179	18	curb	curb	VB
cord-026340-2nf97zvc	179	19	this	this	DT
cord-026340-2nf97zvc	179	20	deadly	deadly	JJ
cord-026340-2nf97zvc	179	21	disease	disease	NN
cord-026340-2nf97zvc	179	22	.	.	.
cord-026340-2nf97zvc	180	1	To	to	TO
cord-026340-2nf97zvc	180	2	rush	rush	VB
cord-026340-2nf97zvc	180	3	through	through	IN
cord-026340-2nf97zvc	180	4	the	the	DT
cord-026340-2nf97zvc	180	5	pandemic	pandemic	NN
cord-026340-2nf97zvc	180	6	,	,	,
cord-026340-2nf97zvc	180	7	one	one	CD
cord-026340-2nf97zvc	180	8	option	option	NN
cord-026340-2nf97zvc	180	9	researchers	researcher	NNS
cord-026340-2nf97zvc	180	10	proposed	propose	VBD
cord-026340-2nf97zvc	180	11	was	be	VBD
cord-026340-2nf97zvc	180	12	to	to	TO
cord-026340-2nf97zvc	180	13	'	'	``
cord-026340-2nf97zvc	180	14	repurpose	repurpose	VB
cord-026340-2nf97zvc	180	15	'	'	''
cord-026340-2nf97zvc	180	16	drug	drug	NN
cord-026340-2nf97zvc	180	17	that	that	WDT
cord-026340-2nf97zvc	180	18	has	have	VBZ
cord-026340-2nf97zvc	180	19	worked	work	VBN
cord-026340-2nf97zvc	180	20	for	for	IN
cord-026340-2nf97zvc	180	21	similar	similar	JJ
cord-026340-2nf97zvc	180	22	diseases	disease	NNS
cord-026340-2nf97zvc	180	23	,	,	,
cord-026340-2nf97zvc	180	24	till	till	IN
cord-026340-2nf97zvc	180	25	herd	herd	NN
cord-026340-2nf97zvc	180	26	immunity	immunity	NN
cord-026340-2nf97zvc	180	27	is	be	VBZ
cord-026340-2nf97zvc	180	28	achieved	achieve	VBN
cord-026340-2nf97zvc	180	29	(	(	-LRB-
cord-026340-2nf97zvc	180	30	Zumla	Zumla	NNP
cord-026340-2nf97zvc	180	31	et	et	FW
cord-026340-2nf97zvc	180	32	al	al	NNP
cord-026340-2nf97zvc	180	33	.	.	.
cord-026340-2nf97zvc	180	34	2016	2016	CD
cord-026340-2nf97zvc	180	35	;	;	:
cord-026340-2nf97zvc	180	36	Li	Li	NNP
cord-026340-2nf97zvc	180	37	and	and	CC
cord-026340-2nf97zvc	180	38	De	De	NNP
cord-026340-2nf97zvc	180	39	Clercq	Clercq	NNP
cord-026340-2nf97zvc	180	40	2020	2020	CD
cord-026340-2nf97zvc	180	41	)	)	-RRB-
cord-026340-2nf97zvc	180	42	.	.	.
cord-026340-2nf97zvc	181	1	When	when	WRB
cord-026340-2nf97zvc	181	2	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	181	3	was	be	VBD
cord-026340-2nf97zvc	181	4	detected	detect	VBN
cord-026340-2nf97zvc	181	5	in	in	IN
cord-026340-2nf97zvc	181	6	Wuhan	Wuhan	NNP
cord-026340-2nf97zvc	181	7	,	,	,
cord-026340-2nf97zvc	181	8	China	China	NNP
cord-026340-2nf97zvc	181	9	resorted	resort	VBD
cord-026340-2nf97zvc	181	10	to	to	TO
cord-026340-2nf97zvc	181	11	test	test	VB
cord-026340-2nf97zvc	181	12	the	the	DT
cord-026340-2nf97zvc	181	13	effectiveness	effectiveness	NN
cord-026340-2nf97zvc	181	14	of	of	IN
cord-026340-2nf97zvc	181	15	anti	anti	JJ
cord-026340-2nf97zvc	181	16	-	-	JJ
cord-026340-2nf97zvc	181	17	viral	viral	JJ
cord-026340-2nf97zvc	181	18	drugs	drug	NNS
cord-026340-2nf97zvc	181	19	and	and	CC
cord-026340-2nf97zvc	181	20	other	other	JJ
cord-026340-2nf97zvc	181	21	infectious	infectious	JJ
cord-026340-2nf97zvc	181	22	diseases	disease	NNS
cord-026340-2nf97zvc	181	23	against	against	IN
cord-026340-2nf97zvc	181	24	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	181	25	.	.	.
cord-026340-2nf97zvc	182	1	How	how	WRB
cord-026340-2nf97zvc	182	2	long	long	RB
cord-026340-2nf97zvc	182	3	has	have	VBZ
cord-026340-2nf97zvc	182	4	it	-PRON-	PRP
cord-026340-2nf97zvc	182	5	been	be	VBN
cord-026340-2nf97zvc	182	6	since	since	IN
cord-026340-2nf97zvc	182	7	we	-PRON-	PRP
cord-026340-2nf97zvc	182	8	know	know	VBP
cord-026340-2nf97zvc	182	9	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	182	10	(	(	-LRB-
cord-026340-2nf97zvc	182	11	CQ	CQ	NNP
cord-026340-2nf97zvc	182	12	,	,	,
cord-026340-2nf97zvc	182	13	9-aminoquinoline	9-aminoquinoline	CD
cord-026340-2nf97zvc	182	14	)	)	-RRB-
cord-026340-2nf97zvc	182	15	?	?	.
cord-026340-2nf97zvc	183	1	It	-PRON-	PRP
cord-026340-2nf97zvc	183	2	is	be	VBZ
cord-026340-2nf97zvc	183	3	believed	believe	VBN
cord-026340-2nf97zvc	183	4	that	that	IN
cord-026340-2nf97zvc	183	5	a	a	DT
cord-026340-2nf97zvc	183	6	scientist	scientist	NN
cord-026340-2nf97zvc	183	7	named	name	VBN
cord-026340-2nf97zvc	183	8	Hans	Hans	NNP
cord-026340-2nf97zvc	183	9	Andersag	Andersag	NNP
cord-026340-2nf97zvc	183	10	and	and	CC
cord-026340-2nf97zvc	183	11	his	-PRON-	PRP$
cord-026340-2nf97zvc	183	12	coworkers	coworker	NNS
cord-026340-2nf97zvc	183	13	discovered	discover	VBD
cord-026340-2nf97zvc	183	14	a	a	DT
cord-026340-2nf97zvc	183	15	derivative	derivative	NN
cord-026340-2nf97zvc	183	16	of	of	IN
cord-026340-2nf97zvc	183	17	CQ	CQ	NNP
cord-026340-2nf97zvc	183	18	at	at	IN
cord-026340-2nf97zvc	183	19	Bayers	Bayers	NNP
cord-026340-2nf97zvc	183	20	Laboratories	Laboratories	NNPS
cord-026340-2nf97zvc	183	21	in	in	IN
cord-026340-2nf97zvc	183	22	1934	1934	CD
cord-026340-2nf97zvc	183	23	(	(	-LRB-
cord-026340-2nf97zvc	183	24	Coatney	Coatney	NNP
cord-026340-2nf97zvc	183	25	1963	1963	CD
cord-026340-2nf97zvc	183	26	)	)	-RRB-
cord-026340-2nf97zvc	183	27	.	.	.
cord-026340-2nf97zvc	184	1	After	after	IN
cord-026340-2nf97zvc	184	2	a	a	DT
cord-026340-2nf97zvc	184	3	long	long	JJ
cord-026340-2nf97zvc	184	4	line	line	NN
cord-026340-2nf97zvc	184	5	of	of	IN
cord-026340-2nf97zvc	184	6	controversy	controversy	NN
cord-026340-2nf97zvc	184	7	as	as	IN
cord-026340-2nf97zvc	184	8	a	a	DT
cord-026340-2nf97zvc	184	9	toxic	toxic	JJ
cord-026340-2nf97zvc	184	10	agent	agent	NN
cord-026340-2nf97zvc	184	11	,	,	,
cord-026340-2nf97zvc	184	12	CQ	CQ	NNP
cord-026340-2nf97zvc	184	13	reinstated	reinstate	VBD
cord-026340-2nf97zvc	184	14	its	-PRON-	PRP$
cord-026340-2nf97zvc	184	15	importance	importance	NN
cord-026340-2nf97zvc	184	16	in	in	IN
cord-026340-2nf97zvc	184	17	1948	1948	CD
cord-026340-2nf97zvc	184	18	by	by	IN
cord-026340-2nf97zvc	184	19	proving	prove	VBG
cord-026340-2nf97zvc	184	20	its	-PRON-	PRP$
cord-026340-2nf97zvc	184	21	effectiveness	effectiveness	NN
cord-026340-2nf97zvc	184	22	against	against	IN
cord-026340-2nf97zvc	184	23	extra	extra	JJ
cord-026340-2nf97zvc	184	24	-	-	JJ
cord-026340-2nf97zvc	184	25	intestinal	intestinal	JJ
cord-026340-2nf97zvc	184	26	amebiasis	amebiasis	NN
cord-026340-2nf97zvc	184	27	(	(	-LRB-
cord-026340-2nf97zvc	184	28	Conan	Conan	NNP
cord-026340-2nf97zvc	184	29	1948	1948	CD
cord-026340-2nf97zvc	184	30	)	)	-RRB-
cord-026340-2nf97zvc	184	31	.	.	.
cord-026340-2nf97zvc	185	1	After	after	IN
cord-026340-2nf97zvc	185	2	the	the	DT
cord-026340-2nf97zvc	185	3	World	World	NNP
cord-026340-2nf97zvc	185	4	War	War	NNP
cord-026340-2nf97zvc	185	5	II	II	NNP
cord-026340-2nf97zvc	185	6	,	,	,
cord-026340-2nf97zvc	185	7	WHO	who	WP
cord-026340-2nf97zvc	185	8	deployed	deploy	VBD
cord-026340-2nf97zvc	185	9	CQ	CQ	NNP
cord-026340-2nf97zvc	185	10	as	as	IN
cord-026340-2nf97zvc	185	11	one	one	CD
cord-026340-2nf97zvc	185	12	of	of	IN
cord-026340-2nf97zvc	185	13	its	-PRON-	PRP$
cord-026340-2nf97zvc	185	14	principal	principal	JJ
cord-026340-2nf97zvc	185	15	arms	arm	NNS
cord-026340-2nf97zvc	185	16	for	for	IN
cord-026340-2nf97zvc	185	17	combating	combat	VBG
cord-026340-2nf97zvc	185	18	malaria	malaria	NN
cord-026340-2nf97zvc	185	19	and	and	CC
cord-026340-2nf97zvc	185	20	now	now	RB
cord-026340-2nf97zvc	185	21	CQ	CQ	NNP
cord-026340-2nf97zvc	185	22	is	be	VBZ
cord-026340-2nf97zvc	185	23	on	on	IN
cord-026340-2nf97zvc	185	24	the	the	DT
cord-026340-2nf97zvc	185	25	organization	organization	NN
cord-026340-2nf97zvc	185	26	's	's	POS
cord-026340-2nf97zvc	185	27	list	list	NN
cord-026340-2nf97zvc	185	28	of	of	IN
cord-026340-2nf97zvc	185	29	essential	essential	JJ
cord-026340-2nf97zvc	185	30	medicines	medicine	NNS
cord-026340-2nf97zvc	185	31	for	for	IN
cord-026340-2nf97zvc	185	32	the	the	DT
cord-026340-2nf97zvc	185	33	same	same	JJ
cord-026340-2nf97zvc	185	34	.	.	.
cord-026340-2nf97zvc	186	1	Today	today	NN
cord-026340-2nf97zvc	186	2	,	,	,
cord-026340-2nf97zvc	186	3	CQ	CQ	NNP
cord-026340-2nf97zvc	186	4	is	be	VBZ
cord-026340-2nf97zvc	186	5	known	know	VBN
cord-026340-2nf97zvc	186	6	to	to	TO
cord-026340-2nf97zvc	186	7	be	be	VB
cord-026340-2nf97zvc	186	8	effective	effective	JJ
cord-026340-2nf97zvc	186	9	against	against	IN
cord-026340-2nf97zvc	186	10	malarial	malarial	JJ
cord-026340-2nf97zvc	186	11	parasites	parasite	NNS
cord-026340-2nf97zvc	186	12	of	of	IN
cord-026340-2nf97zvc	186	13	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	186	14	genus	genus	NN
cord-026340-2nf97zvc	186	15	such	such	JJ
cord-026340-2nf97zvc	186	16	as	as	IN
cord-026340-2nf97zvc	186	17	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	186	18	malariae	malariae	NN
cord-026340-2nf97zvc	186	19	,	,	,
cord-026340-2nf97zvc	186	20	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	186	21	ovale	ovale	NNP
cord-026340-2nf97zvc	186	22	and	and	CC
cord-026340-2nf97zvc	186	23	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	186	24	vivax	vivax	NN
cord-026340-2nf97zvc	186	25	but	but	CC
cord-026340-2nf97zvc	186	26	not	not	RB
cord-026340-2nf97zvc	186	27	against	against	IN
cord-026340-2nf97zvc	186	28	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	186	29	falciparum	falciparum	NN
cord-026340-2nf97zvc	186	30	owing	owe	VBG
cord-026340-2nf97zvc	186	31	to	to	IN
cord-026340-2nf97zvc	186	32	the	the	DT
cord-026340-2nf97zvc	186	33	resistance	resistance	NN
cord-026340-2nf97zvc	186	34	developed	develop	VBN
cord-026340-2nf97zvc	186	35	(	(	-LRB-
cord-026340-2nf97zvc	186	36	Mejia	Mejia	NNP
cord-026340-2nf97zvc	186	37	et	et	NNP
cord-026340-2nf97zvc	186	38	al	al	NNP
cord-026340-2nf97zvc	186	39	.	.	NNP
cord-026340-2nf97zvc	186	40	2013	2013	CD
cord-026340-2nf97zvc	186	41	)	)	-RRB-
cord-026340-2nf97zvc	186	42	.	.	.
cord-026340-2nf97zvc	187	1	How	how	WRB
cord-026340-2nf97zvc	187	2	does	do	VBZ
cord-026340-2nf97zvc	187	3	CQ	CQ	NNP
cord-026340-2nf97zvc	187	4	help	help	VB
cord-026340-2nf97zvc	187	5	eliminate	eliminate	VB
cord-026340-2nf97zvc	187	6	malarial	malarial	JJ
cord-026340-2nf97zvc	187	7	parasite	parasite	NN
cord-026340-2nf97zvc	187	8	?	?	.
cord-026340-2nf97zvc	188	1	During	during	IN
cord-026340-2nf97zvc	188	2	malaria	malaria	NN
cord-026340-2nf97zvc	188	3	,	,	,
cord-026340-2nf97zvc	188	4	the	the	DT
cord-026340-2nf97zvc	188	5	malarial	malarial	JJ
cord-026340-2nf97zvc	188	6	pathogen	pathogen	NN
cord-026340-2nf97zvc	188	7	attacks	attack	NNS
cord-026340-2nf97zvc	188	8	red	red	JJ
cord-026340-2nf97zvc	188	9	blood	blood	NN
cord-026340-2nf97zvc	188	10	cell	cell	NN
cord-026340-2nf97zvc	188	11	and	and	CC
cord-026340-2nf97zvc	188	12	degrades	degrade	VBZ
cord-026340-2nf97zvc	188	13	hemoglobin	hemoglobin	NN
cord-026340-2nf97zvc	188	14	in	in	IN
cord-026340-2nf97zvc	188	15	vacuoles	vacuole	NNS
cord-026340-2nf97zvc	188	16	of	of	IN
cord-026340-2nf97zvc	188	17	the	the	DT
cord-026340-2nf97zvc	188	18	parasitic	parasitic	JJ
cord-026340-2nf97zvc	188	19	cell	cell	NN
cord-026340-2nf97zvc	188	20	and	and	CC
cord-026340-2nf97zvc	188	21	acquires	acquire	VBZ
cord-026340-2nf97zvc	188	22	those	those	DT
cord-026340-2nf97zvc	188	23	amino	amino	NN
cord-026340-2nf97zvc	188	24	acids	acid	NNS
cord-026340-2nf97zvc	188	25	for	for	IN
cord-026340-2nf97zvc	188	26	constructing	construct	VBG
cord-026340-2nf97zvc	188	27	its	-PRON-	PRP$
cord-026340-2nf97zvc	188	28	proteins	protein	NNS
cord-026340-2nf97zvc	188	29	and	and	CC
cord-026340-2nf97zvc	188	30	energy	energy	NN
cord-026340-2nf97zvc	188	31	metabolism	metabolism	NN
cord-026340-2nf97zvc	188	32	.	.	.
cord-026340-2nf97zvc	189	1	CQ	CQ	NNP
cord-026340-2nf97zvc	189	2	is	be	VBZ
cord-026340-2nf97zvc	189	3	basically	basically	RB
cord-026340-2nf97zvc	189	4	a	a	DT
cord-026340-2nf97zvc	189	5	lysomotrophic	lysomotrophic	JJ
cord-026340-2nf97zvc	189	6	agent	agent	NN
cord-026340-2nf97zvc	189	7	and	and	CC
cord-026340-2nf97zvc	189	8	crosses	cross	VBZ
cord-026340-2nf97zvc	189	9	plasma	plasma	NN
cord-026340-2nf97zvc	189	10	membrane	membrane	NN
cord-026340-2nf97zvc	189	11	and	and	CC
cord-026340-2nf97zvc	189	12	organelle	organelle	NN
cord-026340-2nf97zvc	189	13	membranes	membrane	NNS
cord-026340-2nf97zvc	189	14	by	by	IN
cord-026340-2nf97zvc	189	15	simple	simple	JJ
cord-026340-2nf97zvc	189	16	diffusion	diffusion	NN
cord-026340-2nf97zvc	189	17	process	process	NN
cord-026340-2nf97zvc	189	18	.	.	.
cord-026340-2nf97zvc	190	1	Once	once	IN
cord-026340-2nf97zvc	190	2	inside	inside	IN
cord-026340-2nf97zvc	190	3	the	the	DT
cord-026340-2nf97zvc	190	4	acidic	acidic	JJ
cord-026340-2nf97zvc	190	5	organelles	organelle	NNS
cord-026340-2nf97zvc	190	6	,	,	,
cord-026340-2nf97zvc	190	7	CQ	CQ	NNP
cord-026340-2nf97zvc	190	8	gets	get	VBZ
cord-026340-2nf97zvc	190	9	protonated	protonate	VBN
cord-026340-2nf97zvc	190	10	and	and	CC
cord-026340-2nf97zvc	190	11	can	can	MD
cord-026340-2nf97zvc	190	12	not	not	RB
cord-026340-2nf97zvc	190	13	leave	leave	VB
cord-026340-2nf97zvc	190	14	the	the	DT
cord-026340-2nf97zvc	190	15	site	site	NN
cord-026340-2nf97zvc	190	16	by	by	IN
cord-026340-2nf97zvc	190	17	diffusion	diffusion	NN
cord-026340-2nf97zvc	190	18	.	.	.
cord-026340-2nf97zvc	191	1	CQ	CQ	NNP
cord-026340-2nf97zvc	191	2	,	,	,
cord-026340-2nf97zvc	191	3	therefore	therefore	RB
cord-026340-2nf97zvc	191	4	,	,	,
cord-026340-2nf97zvc	191	5	gets	get	VBZ
cord-026340-2nf97zvc	191	6	concentrated	concentrate	VBN
cord-026340-2nf97zvc	191	7	in	in	IN
cord-026340-2nf97zvc	191	8	the	the	DT
cord-026340-2nf97zvc	191	9	acidic	acidic	JJ
cord-026340-2nf97zvc	191	10	organelles	organelle	NNS
cord-026340-2nf97zvc	191	11	herein	herein	RB
cord-026340-2nf97zvc	191	12	the	the	DT
cord-026340-2nf97zvc	191	13	parasitic	parasitic	JJ
cord-026340-2nf97zvc	191	14	vacuoles	vacuole	NNS
cord-026340-2nf97zvc	191	15	,	,	,
cord-026340-2nf97zvc	191	16	changing	change	VBG
cord-026340-2nf97zvc	191	17	the	the	DT
cord-026340-2nf97zvc	191	18	pH	ph	NN
cord-026340-2nf97zvc	191	19	and	and	CC
cord-026340-2nf97zvc	191	20	facilitating	facilitate	VBG
cord-026340-2nf97zvc	191	21	the	the	DT
cord-026340-2nf97zvc	191	22	formation	formation	NN
cord-026340-2nf97zvc	191	23	of	of	IN
cord-026340-2nf97zvc	191	24	a	a	DT
cord-026340-2nf97zvc	191	25	complex	complex	NN
cord-026340-2nf97zvc	191	26	of	of	IN
cord-026340-2nf97zvc	191	27	'	'	``
cord-026340-2nf97zvc	191	28	heme	heme	NNP
cord-026340-2nf97zvc	191	29	and	and	CC
cord-026340-2nf97zvc	191	30	chloroquine	chloroquine	NNP
cord-026340-2nf97zvc	191	31	'	'	''
cord-026340-2nf97zvc	191	32	that	that	WDT
cord-026340-2nf97zvc	191	33	prevents	prevent	VBZ
cord-026340-2nf97zvc	191	34	parasites	parasite	NNS
cord-026340-2nf97zvc	191	35	of	of	IN
cord-026340-2nf97zvc	191	36	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	191	37	genus	genus	NN
cord-026340-2nf97zvc	191	38	from	from	IN
cord-026340-2nf97zvc	191	39	drawing	draw	VBG
cord-026340-2nf97zvc	191	40	nutrients	nutrient	NNS
cord-026340-2nf97zvc	191	41	from	from	IN
cord-026340-2nf97zvc	191	42	the	the	DT
cord-026340-2nf97zvc	191	43	red	red	JJ
cord-026340-2nf97zvc	191	44	blood	blood	NN
cord-026340-2nf97zvc	191	45	cell	cell	NN
cord-026340-2nf97zvc	191	46	.	.	.
cord-026340-2nf97zvc	192	1	CQ	CQ	NNP
cord-026340-2nf97zvc	192	2	can	can	MD
cord-026340-2nf97zvc	192	3	be	be	VB
cord-026340-2nf97zvc	192	4	transported	transport	VBN
cord-026340-2nf97zvc	192	5	out	out	IN
cord-026340-2nf97zvc	192	6	of	of	IN
cord-026340-2nf97zvc	192	7	cells	cell	NNS
cord-026340-2nf97zvc	192	8	via	via	IN
cord-026340-2nf97zvc	192	9	a	a	DT
cord-026340-2nf97zvc	192	10	protein	protein	NN
cord-026340-2nf97zvc	192	11	called	call	VBN
cord-026340-2nf97zvc	192	12	multi	multi	JJ
cord-026340-2nf97zvc	192	13	-	-	JJ
cord-026340-2nf97zvc	192	14	drug	drug	JJ
cord-026340-2nf97zvc	192	15	resistance	resistance	NN
cord-026340-2nf97zvc	192	16	protein	protein	NN
cord-026340-2nf97zvc	192	17	or	or	CC
cord-026340-2nf97zvc	192	18	MRP-1	MRP-1	NNP
cord-026340-2nf97zvc	192	19	,	,	,
cord-026340-2nf97zvc	192	20	an	an	DT
cord-026340-2nf97zvc	192	21	ATP	ATP	NNP
cord-026340-2nf97zvc	192	22	binding	bind	VBG
cord-026340-2nf97zvc	192	23	protein	protein	NN
cord-026340-2nf97zvc	192	24	(	(	-LRB-
cord-026340-2nf97zvc	192	25	Mejia	Mejia	NNP
cord-026340-2nf97zvc	192	26	et	et	NNP
cord-026340-2nf97zvc	192	27	al	al	NNP
cord-026340-2nf97zvc	192	28	.	.	NNP
cord-026340-2nf97zvc	192	29	2013	2013	CD
cord-026340-2nf97zvc	192	30	;	;	:
cord-026340-2nf97zvc	192	31	Mauthe	Mauthe	NNP
cord-026340-2nf97zvc	192	32	et	et	FW
cord-026340-2nf97zvc	192	33	al	al	NNP
cord-026340-2nf97zvc	192	34	.	.	.
cord-026340-2nf97zvc	192	35	2018	2018	CD
cord-026340-2nf97zvc	192	36	)	)	-RRB-
cord-026340-2nf97zvc	192	37	.	.	.
cord-026340-2nf97zvc	193	1	Does	do	VBZ
cord-026340-2nf97zvc	193	2	CQ	CQ	NNP
cord-026340-2nf97zvc	193	3	have	have	VB
cord-026340-2nf97zvc	193	4	anti	anti	JJ
cord-026340-2nf97zvc	193	5	-	-	JJ
cord-026340-2nf97zvc	193	6	viral	viral	JJ
cord-026340-2nf97zvc	193	7	effects	effect	NNS
cord-026340-2nf97zvc	193	8	?	?	.
cord-026340-2nf97zvc	194	1	Literature	literature	NN
cord-026340-2nf97zvc	194	2	cites	cite	VBZ
cord-026340-2nf97zvc	194	3	that	that	IN
cord-026340-2nf97zvc	194	4	CQ	CQ	NNP
cord-026340-2nf97zvc	194	5	exerts	exert	VBZ
cord-026340-2nf97zvc	194	6	effects	effect	NNS
cord-026340-2nf97zvc	194	7	against	against	IN
cord-026340-2nf97zvc	194	8	a	a	DT
cord-026340-2nf97zvc	194	9	battery	battery	NN
cord-026340-2nf97zvc	194	10	of	of	IN
cord-026340-2nf97zvc	194	11	different	different	JJ
cord-026340-2nf97zvc	194	12	viruses	virus	NNS
cord-026340-2nf97zvc	194	13	such	such	JJ
cord-026340-2nf97zvc	194	14	as	as	IN
cord-026340-2nf97zvc	194	15	flaviviruses	flavivirus	NNS
cord-026340-2nf97zvc	194	16	,	,	,
cord-026340-2nf97zvc	194	17	retroviruses	retrovirus	NNS
cord-026340-2nf97zvc	194	18	and	and	CC
cord-026340-2nf97zvc	194	19	corona	corona	NN
cord-026340-2nf97zvc	194	20	viruses	virus	NNS
cord-026340-2nf97zvc	194	21	.	.	.
cord-026340-2nf97zvc	195	1	CQ	CQ	NNP
cord-026340-2nf97zvc	195	2	and	and	CC
cord-026340-2nf97zvc	195	3	HCQ	HCQ	NNP
cord-026340-2nf97zvc	195	4	have	have	VBP
cord-026340-2nf97zvc	195	5	demonstrated	demonstrate	VBN
cord-026340-2nf97zvc	195	6	anti	anti	JJ
cord-026340-2nf97zvc	195	7	-	-	JJ
cord-026340-2nf97zvc	195	8	viral	viral	JJ
cord-026340-2nf97zvc	195	9	potency	potency	NN
cord-026340-2nf97zvc	195	10	against	against	IN
cord-026340-2nf97zvc	195	11	Herpes	Herpes	NNP
cord-026340-2nf97zvc	195	12	simplex	simplex	NN
cord-026340-2nf97zvc	195	13	virus	virus	NN
cord-026340-2nf97zvc	195	14	type	type	NN
cord-026340-2nf97zvc	195	15	1	1	CD
cord-026340-2nf97zvc	195	16	,	,	,
cord-026340-2nf97zvc	195	17	Zika	Zika	NNP
cord-026340-2nf97zvc	195	18	,	,	,
cord-026340-2nf97zvc	195	19	HIV	HIV	NNP
cord-026340-2nf97zvc	195	20	,	,	,
cord-026340-2nf97zvc	195	21	MERS	MERS	NNP
cord-026340-2nf97zvc	195	22	,	,	,
cord-026340-2nf97zvc	195	23	SARS	SARS	NNP
cord-026340-2nf97zvc	195	24	-	-	HYPH
cord-026340-2nf97zvc	195	25	CoV	CoV	NNP
cord-026340-2nf97zvc	195	26	,	,	,
cord-026340-2nf97zvc	195	27	HCoV	HCoV	NNP
cord-026340-2nf97zvc	195	28	-	-	HYPH
cord-026340-2nf97zvc	195	29	OC43	OC43	NNP
cord-026340-2nf97zvc	195	30	,	,	,
cord-026340-2nf97zvc	195	31	Chikungunya	Chikungunya	NNP
cord-026340-2nf97zvc	195	32	and	and	CC
cord-026340-2nf97zvc	195	33	Hepatitis	Hepatitis	NNP
cord-026340-2nf97zvc	195	34	C	C	NNP
cord-026340-2nf97zvc	195	35	(	(	-LRB-
cord-026340-2nf97zvc	195	36	Picot	Picot	NNP
cord-026340-2nf97zvc	195	37	2020	2020	CD
cord-026340-2nf97zvc	195	38	)	)	-RRB-
cord-026340-2nf97zvc	195	39	.	.	.
cord-026340-2nf97zvc	196	1	Of	of	IN
cord-026340-2nf97zvc	196	2	the	the	DT
cord-026340-2nf97zvc	196	3	different	different	JJ
cord-026340-2nf97zvc	196	4	mechanisms	mechanism	NNS
cord-026340-2nf97zvc	196	5	of	of	IN
cord-026340-2nf97zvc	196	6	anti	anti	JJ
cord-026340-2nf97zvc	196	7	-	-	JJ
cord-026340-2nf97zvc	196	8	viral	viral	JJ
cord-026340-2nf97zvc	196	9	action	action	NN
cord-026340-2nf97zvc	196	10	known	know	VBN
cord-026340-2nf97zvc	196	11	for	for	IN
cord-026340-2nf97zvc	196	12	CQ	CQ	NNP
cord-026340-2nf97zvc	196	13	,	,	,
cord-026340-2nf97zvc	196	14	the	the	DT
cord-026340-2nf97zvc	196	15	most	most	RBS
cord-026340-2nf97zvc	196	16	intriguing	intriguing	JJ
cord-026340-2nf97zvc	196	17	one	one	NN
cord-026340-2nf97zvc	196	18	is	be	VBZ
cord-026340-2nf97zvc	196	19	its	-PRON-	PRP$
cord-026340-2nf97zvc	196	20	ability	ability	NN
cord-026340-2nf97zvc	196	21	to	to	TO
cord-026340-2nf97zvc	196	22	inhibit	inhibit	VB
cord-026340-2nf97zvc	196	23	viruses	virus	NNS
cord-026340-2nf97zvc	196	24	at	at	IN
cord-026340-2nf97zvc	196	25	the	the	DT
cord-026340-2nf97zvc	196	26	entry	entry	NN
cord-026340-2nf97zvc	196	27	point	point	NN
cord-026340-2nf97zvc	196	28	of	of	IN
cord-026340-2nf97zvc	196	29	host	host	NN
cord-026340-2nf97zvc	196	30	cell	cell	NN
cord-026340-2nf97zvc	196	31	which	which	WDT
cord-026340-2nf97zvc	196	32	happens	happen	VBZ
cord-026340-2nf97zvc	196	33	in	in	IN
cord-026340-2nf97zvc	196	34	the	the	DT
cord-026340-2nf97zvc	196	35	case	case	NN
cord-026340-2nf97zvc	196	36	of	of	IN
cord-026340-2nf97zvc	196	37	Borna	Borna	NNP
cord-026340-2nf97zvc	196	38	disease	disease	NN
cord-026340-2nf97zvc	196	39	virus	virus	NN
cord-026340-2nf97zvc	196	40	,	,	,
cord-026340-2nf97zvc	196	41	Minute	minute	NN
cord-026340-2nf97zvc	196	42	virus	virus	NN
cord-026340-2nf97zvc	196	43	of	of	IN
cord-026340-2nf97zvc	196	44	mice	mouse	NNS
cord-026340-2nf97zvc	196	45	MVMp	MVMp	NNS
cord-026340-2nf97zvc	196	46	and	and	CC
cord-026340-2nf97zvc	196	47	the	the	DT
cord-026340-2nf97zvc	196	48	Avian	avian	JJ
cord-026340-2nf97zvc	196	49	leucosis	leucosis	NN
cord-026340-2nf97zvc	196	50	virus	virus	NN
cord-026340-2nf97zvc	196	51	(	(	-LRB-
cord-026340-2nf97zvc	196	52	Savarino	Savarino	NNP
cord-026340-2nf97zvc	196	53	et	et	NNP
cord-026340-2nf97zvc	196	54	al	al	NNP
cord-026340-2nf97zvc	196	55	.	.	NNP
cord-026340-2nf97zvc	196	56	2003	2003	CD
cord-026340-2nf97zvc	196	57	)	)	-RRB-
cord-026340-2nf97zvc	196	58	.	.	.
cord-026340-2nf97zvc	197	1	In	in	IN
cord-026340-2nf97zvc	197	2	the	the	DT
cord-026340-2nf97zvc	197	3	case	case	NN
cord-026340-2nf97zvc	197	4	hepatitis	hepatitis	NN
cord-026340-2nf97zvc	197	5	A	A	NNP
cord-026340-2nf97zvc	197	6	virus	virus	NN
cord-026340-2nf97zvc	197	7	,	,	,
cord-026340-2nf97zvc	197	8	CQ	CQ	NNP
cord-026340-2nf97zvc	197	9	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	197	10	uncoating	uncoating	NN
cord-026340-2nf97zvc	197	11	of	of	IN
cord-026340-2nf97zvc	197	12	the	the	DT
cord-026340-2nf97zvc	197	13	virus	virus	NN
cord-026340-2nf97zvc	197	14	and	and	CC
cord-026340-2nf97zvc	197	15	,	,	,
cord-026340-2nf97zvc	197	16	thus	thus	RB
cord-026340-2nf97zvc	197	17	,	,	,
cord-026340-2nf97zvc	197	18	blocking	block	VBG
cord-026340-2nf97zvc	197	19	its	-PRON-	PRP$
cord-026340-2nf97zvc	197	20	entire	entire	JJ
cord-026340-2nf97zvc	197	21	replication	replication	NN
cord-026340-2nf97zvc	197	22	cycle	cycle	NN
cord-026340-2nf97zvc	197	23	(	(	-LRB-
cord-026340-2nf97zvc	197	24	Bishop	Bishop	NNP
cord-026340-2nf97zvc	197	25	1998	1998	CD
cord-026340-2nf97zvc	197	26	,	,	,
cord-026340-2nf97zvc	197	27	Devaux	Devaux	NNP
cord-026340-2nf97zvc	197	28	et	et	NNP
cord-026340-2nf97zvc	197	29	al	al	NNP
cord-026340-2nf97zvc	197	30	.	.	.
cord-026340-2nf97zvc	197	31	2020	2020	CD
cord-026340-2nf97zvc	197	32	.	.	.
cord-026340-2nf97zvc	198	1	Once	once	IN
cord-026340-2nf97zvc	198	2	inside	inside	IN
cord-026340-2nf97zvc	198	3	the	the	DT
cord-026340-2nf97zvc	198	4	cell	cell	NN
cord-026340-2nf97zvc	198	5	,	,	,
cord-026340-2nf97zvc	198	6	CQ	CQ	NNP
cord-026340-2nf97zvc	198	7	works	work	VBZ
cord-026340-2nf97zvc	198	8	by	by	IN
cord-026340-2nf97zvc	198	9	inhibiting	inhibit	VBG
cord-026340-2nf97zvc	198	10	the	the	DT
cord-026340-2nf97zvc	198	11	replication	replication	NN
cord-026340-2nf97zvc	198	12	of	of	IN
cord-026340-2nf97zvc	198	13	a	a	DT
cord-026340-2nf97zvc	198	14	virus	virus	NN
cord-026340-2nf97zvc	198	15	by	by	IN
cord-026340-2nf97zvc	198	16	altering	alter	VBG
cord-026340-2nf97zvc	198	17	the	the	DT
cord-026340-2nf97zvc	198	18	pH	ph	NN
cord-026340-2nf97zvc	198	19	of	of	IN
cord-026340-2nf97zvc	198	20	acidic	acidic	JJ
cord-026340-2nf97zvc	198	21	organelles	organelle	NNS
cord-026340-2nf97zvc	198	22	that	that	WDT
cord-026340-2nf97zvc	198	23	are	be	VBP
cord-026340-2nf97zvc	198	24	sites	site	NNS
cord-026340-2nf97zvc	198	25	of	of	IN
cord-026340-2nf97zvc	198	26	viral	viral	JJ
cord-026340-2nf97zvc	198	27	DNA	dna	NN
cord-026340-2nf97zvc	198	28	replication	replication	NN
cord-026340-2nf97zvc	198	29	(	(	-LRB-
cord-026340-2nf97zvc	198	30	Devaux	Devaux	NNP
cord-026340-2nf97zvc	198	31	et	et	NNP
cord-026340-2nf97zvc	198	32	al	al	NNP
cord-026340-2nf97zvc	198	33	.	.	NNP
cord-026340-2nf97zvc	198	34	2020	2020	CD
cord-026340-2nf97zvc	198	35	)	)	-RRB-
cord-026340-2nf97zvc	198	36	.	.	.
cord-026340-2nf97zvc	199	1	Apart	apart	RB
cord-026340-2nf97zvc	199	2	from	from	IN
cord-026340-2nf97zvc	199	3	blocking	block	VBG
cord-026340-2nf97zvc	199	4	viral	viral	JJ
cord-026340-2nf97zvc	199	5	entry	entry	NN
cord-026340-2nf97zvc	199	6	and	and	CC
cord-026340-2nf97zvc	199	7	viral	viral	JJ
cord-026340-2nf97zvc	199	8	replication	replication	NN
cord-026340-2nf97zvc	199	9	,	,	,
cord-026340-2nf97zvc	199	10	CQ	CQ	NNP
cord-026340-2nf97zvc	199	11	can	can	MD
cord-026340-2nf97zvc	199	12	also	also	RB
cord-026340-2nf97zvc	199	13	block	block	VB
cord-026340-2nf97zvc	199	14	the	the	DT
cord-026340-2nf97zvc	199	15	final	final	JJ
cord-026340-2nf97zvc	199	16	packaging	packaging	NN
cord-026340-2nf97zvc	199	17	process	process	NN
cord-026340-2nf97zvc	199	18	in	in	IN
cord-026340-2nf97zvc	199	19	certain	certain	JJ
cord-026340-2nf97zvc	199	20	viruses	virus	NNS
cord-026340-2nf97zvc	199	21	.	.	.
cord-026340-2nf97zvc	200	1	Eg	eg	UH
cord-026340-2nf97zvc	200	2	,	,	,
cord-026340-2nf97zvc	200	3	in	in	IN
cord-026340-2nf97zvc	200	4	the	the	DT
cord-026340-2nf97zvc	200	5	case	case	NN
cord-026340-2nf97zvc	200	6	of	of	IN
cord-026340-2nf97zvc	200	7	infection	infection	NN
cord-026340-2nf97zvc	200	8	caused	cause	VBN
cord-026340-2nf97zvc	200	9	by	by	IN
cord-026340-2nf97zvc	200	10	enveloped	envelop	VBN
cord-026340-2nf97zvc	200	11	viruses	virus	NNS
cord-026340-2nf97zvc	200	12	like	like	IN
cord-026340-2nf97zvc	200	13	Mayaro	Mayaro	NNP
cord-026340-2nf97zvc	200	14	viruses	virus	NNS
cord-026340-2nf97zvc	200	15	,	,	,
cord-026340-2nf97zvc	200	16	CQ	CQ	NNP
cord-026340-2nf97zvc	200	17	administration	administration	NN
cord-026340-2nf97zvc	200	18	causes	cause	VBZ
cord-026340-2nf97zvc	200	19	accumulation	accumulation	NN
cord-026340-2nf97zvc	200	20	of	of	IN
cord-026340-2nf97zvc	200	21	the	the	DT
cord-026340-2nf97zvc	200	22	base	base	NN
cord-026340-2nf97zvc	200	23	in	in	IN
cord-026340-2nf97zvc	200	24	endoplasmic	endoplasmic	NN
cord-026340-2nf97zvc	200	25	and	and	CC
cord-026340-2nf97zvc	200	26	trans	trans	JJ
cord-026340-2nf97zvc	200	27	-	-	JJ
cord-026340-2nf97zvc	200	28	golgi	golgi	NNP
cord-026340-2nf97zvc	200	29	compartments	compartment	NNS
cord-026340-2nf97zvc	200	30	of	of	IN
cord-026340-2nf97zvc	200	31	the	the	DT
cord-026340-2nf97zvc	200	32	cell	cell	NN
cord-026340-2nf97zvc	200	33	.	.	.
cord-026340-2nf97zvc	201	1	This	this	DT
cord-026340-2nf97zvc	201	2	affects	affect	VBZ
cord-026340-2nf97zvc	201	3	the	the	DT
cord-026340-2nf97zvc	201	4	functioning	functioning	NN
cord-026340-2nf97zvc	201	5	of	of	IN
cord-026340-2nf97zvc	201	6	certain	certain	JJ
cord-026340-2nf97zvc	201	7	low	low	JJ
cord-026340-2nf97zvc	201	8	pH	ph	NN
cord-026340-2nf97zvc	201	9	-	-	HYPH
cord-026340-2nf97zvc	201	10	dependent	dependent	JJ
cord-026340-2nf97zvc	201	11	proteases	protease	NNS
cord-026340-2nf97zvc	201	12	and	and	CC
cord-026340-2nf97zvc	201	13	glycosyl	glycosyl	NN
cord-026340-2nf97zvc	201	14	-	-	HYPH
cord-026340-2nf97zvc	201	15	transferases	transferase	NNS
cord-026340-2nf97zvc	201	16	which	which	WDT
cord-026340-2nf97zvc	201	17	are	be	VBP
cord-026340-2nf97zvc	201	18	required	require	VBN
cord-026340-2nf97zvc	201	19	for	for	IN
cord-026340-2nf97zvc	201	20	formation	formation	NN
cord-026340-2nf97zvc	201	21	of	of	IN
cord-026340-2nf97zvc	201	22	viral	viral	JJ
cord-026340-2nf97zvc	201	23	envelopes	envelope	NNS
cord-026340-2nf97zvc	201	24	(	(	-LRB-
cord-026340-2nf97zvc	201	25	Savarino	Savarino	NNP
cord-026340-2nf97zvc	201	26	et	et	NNP
cord-026340-2nf97zvc	201	27	al	al	NNP
cord-026340-2nf97zvc	201	28	.	.	NNP
cord-026340-2nf97zvc	201	29	2003	2003	CD
cord-026340-2nf97zvc	201	30	)	)	-RRB-
cord-026340-2nf97zvc	201	31	.	.	.
cord-026340-2nf97zvc	202	1	In	in	IN
cord-026340-2nf97zvc	202	2	Flaviviridae	Flaviviridae	NNP
cord-026340-2nf97zvc	202	3	viruses	virus	NNS
cord-026340-2nf97zvc	202	4	,	,	,
cord-026340-2nf97zvc	202	5	CQ	CQ	NNP
cord-026340-2nf97zvc	202	6	affects	affect	VBZ
cord-026340-2nf97zvc	202	7	normal	normal	JJ
cord-026340-2nf97zvc	202	8	proteolytic	proteolytic	JJ
cord-026340-2nf97zvc	202	9	processing	processing	NN
cord-026340-2nf97zvc	202	10	of	of	IN
cord-026340-2nf97zvc	202	11	flavivirus	flavivirus	JJ
cord-026340-2nf97zvc	202	12	prM	prm	JJ
cord-026340-2nf97zvc	202	13	protein	protein	NN
cord-026340-2nf97zvc	202	14	to	to	IN
cord-026340-2nf97zvc	202	15	M	M	NNP
cord-026340-2nf97zvc	202	16	protein	protein	NN
cord-026340-2nf97zvc	202	17	(	(	-LRB-
cord-026340-2nf97zvc	202	18	Savarino	Savarino	NNP
cord-026340-2nf97zvc	202	19	et	et	NNP
cord-026340-2nf97zvc	202	20	al	al	NNP
cord-026340-2nf97zvc	202	21	.	.	NNP
cord-026340-2nf97zvc	202	22	2003	2003	CD
cord-026340-2nf97zvc	202	23	)	)	-RRB-
cord-026340-2nf97zvc	202	24	.	.	.
cord-026340-2nf97zvc	203	1	For	for	IN
cord-026340-2nf97zvc	203	2	non	non	JJ
cord-026340-2nf97zvc	203	3	-	-	JJ
cord-026340-2nf97zvc	203	4	infectious	infectious	JJ
cord-026340-2nf97zvc	203	5	retrovirus	retrovirus	NN
cord-026340-2nf97zvc	203	6	particles	particle	NNS
cord-026340-2nf97zvc	203	7	,	,	,
cord-026340-2nf97zvc	203	8	as	as	IN
cord-026340-2nf97zvc	203	9	shown	show	VBN
cord-026340-2nf97zvc	203	10	with	with	IN
cord-026340-2nf97zvc	203	11	the	the	DT
cord-026340-2nf97zvc	203	12	Avian	avian	JJ
cord-026340-2nf97zvc	203	13	reticuloendotheliosis	reticuloendotheliosis	NN
cord-026340-2nf97zvc	203	14	virus	virus	NN
cord-026340-2nf97zvc	203	15	,	,	,
cord-026340-2nf97zvc	203	16	CQ	CQ	NNP
cord-026340-2nf97zvc	203	17	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	203	18	glycosylation	glycosylation	NN
cord-026340-2nf97zvc	203	19	of	of	IN
cord-026340-2nf97zvc	203	20	envelope	envelope	NN
cord-026340-2nf97zvc	203	21	glycoproteins	glycoprotein	NNS
cord-026340-2nf97zvc	203	22	(	(	-LRB-
cord-026340-2nf97zvc	203	23	Savarino	Savarino	NNP
cord-026340-2nf97zvc	203	24	et	et	NNP
cord-026340-2nf97zvc	203	25	al	al	NNP
cord-026340-2nf97zvc	203	26	.	.	NNP
cord-026340-2nf97zvc	203	27	2003	2003	CD
cord-026340-2nf97zvc	203	28	)	)	-RRB-
cord-026340-2nf97zvc	203	29	.	.	.
cord-026340-2nf97zvc	204	1	Again	again	RB
cord-026340-2nf97zvc	204	2	in	in	IN
cord-026340-2nf97zvc	204	3	the	the	DT
cord-026340-2nf97zvc	204	4	case	case	NN
cord-026340-2nf97zvc	204	5	of	of	IN
cord-026340-2nf97zvc	204	6	HIV	HIV	NNP
cord-026340-2nf97zvc	204	7	,	,	,
cord-026340-2nf97zvc	204	8	CQ	CQ	NNP
cord-026340-2nf97zvc	204	9	reduces	reduce	VBZ
cord-026340-2nf97zvc	204	10	the	the	DT
cord-026340-2nf97zvc	204	11	production	production	NN
cord-026340-2nf97zvc	204	12	of	of	IN
cord-026340-2nf97zvc	204	13	the	the	DT
cord-026340-2nf97zvc	204	14	heavily	heavily	RB
cord-026340-2nf97zvc	204	15	glycosylated	glycosylated	JJ
cord-026340-2nf97zvc	204	16	epitope	epitope	NN
cord-026340-2nf97zvc	204	17	2G12	2g12	CD
cord-026340-2nf97zvc	204	18	,	,	,
cord-026340-2nf97zvc	204	19	which	which	WDT
cord-026340-2nf97zvc	204	20	is	be	VBZ
cord-026340-2nf97zvc	204	21	located	locate	VBN
cord-026340-2nf97zvc	204	22	on	on	IN
cord-026340-2nf97zvc	204	23	the	the	DT
cord-026340-2nf97zvc	204	24	gp120	gp120	NNP
cord-026340-2nf97zvc	204	25	envelope	envelope	NN
cord-026340-2nf97zvc	204	26	glycoprotein	glycoprotein	NN
cord-026340-2nf97zvc	204	27	surface	surface	NN
cord-026340-2nf97zvc	204	28	which	which	WDT
cord-026340-2nf97zvc	204	29	is	be	VBZ
cord-026340-2nf97zvc	204	30	fundamental	fundamental	JJ
cord-026340-2nf97zvc	204	31	for	for	IN
cord-026340-2nf97zvc	204	32	virus	virus	NN
cord-026340-2nf97zvc	204	33	infectivity	infectivity	NN
cord-026340-2nf97zvc	204	34	.	.	.
cord-026340-2nf97zvc	205	1	Again	again	RB
cord-026340-2nf97zvc	205	2	,	,	,
cord-026340-2nf97zvc	205	3	these	these	DT
cord-026340-2nf97zvc	205	4	effects	effect	NNS
cord-026340-2nf97zvc	205	5	are	be	VBP
cord-026340-2nf97zvc	205	6	likely	likely	JJ
cord-026340-2nf97zvc	205	7	to	to	TO
cord-026340-2nf97zvc	205	8	be	be	VB
cord-026340-2nf97zvc	205	9	attributed	attribute	VBN
cord-026340-2nf97zvc	205	10	to	to	IN
cord-026340-2nf97zvc	205	11	the	the	DT
cord-026340-2nf97zvc	205	12	increased	increase	VBN
cord-026340-2nf97zvc	205	13	pH	ph	NN
cord-026340-2nf97zvc	205	14	in	in	IN
cord-026340-2nf97zvc	205	15	trans	trans	NNP
cord-026340-2nf97zvc	205	16	-	-	JJ
cord-026340-2nf97zvc	205	17	golgi	golgi	NNP
cord-026340-2nf97zvc	205	18	network	network	NN
cord-026340-2nf97zvc	205	19	,	,	,
cord-026340-2nf97zvc	205	20	which	which	WDT
cord-026340-2nf97zvc	205	21	impairs	impair	VBZ
cord-026340-2nf97zvc	205	22	the	the	DT
cord-026340-2nf97zvc	205	23	function	function	NN
cord-026340-2nf97zvc	205	24	of	of	IN
cord-026340-2nf97zvc	205	25	glycosyl	glycosyl	NN
cord-026340-2nf97zvc	205	26	-	-	HYPH
cord-026340-2nf97zvc	205	27	transferases	transferase	NNS
cord-026340-2nf97zvc	205	28	involved	involve	VBN
cord-026340-2nf97zvc	205	29	in	in	IN
cord-026340-2nf97zvc	205	30	the	the	DT
cord-026340-2nf97zvc	205	31	post	post	JJ
cord-026340-2nf97zvc	205	32	-	-	JJ
cord-026340-2nf97zvc	205	33	translational	translational	JJ
cord-026340-2nf97zvc	205	34	processing	processing	NN
cord-026340-2nf97zvc	205	35	of	of	IN
cord-026340-2nf97zvc	205	36	the	the	DT
cord-026340-2nf97zvc	205	37	HIV	HIV	NNP
cord-026340-2nf97zvc	205	38	glycoproteins	glycoprotein	NNS
cord-026340-2nf97zvc	205	39	(	(	-LRB-
cord-026340-2nf97zvc	205	40	Savarino	Savarino	NNP
cord-026340-2nf97zvc	205	41	et	et	NNP
cord-026340-2nf97zvc	205	42	al	al	NNP
cord-026340-2nf97zvc	205	43	.	.	NNP
cord-026340-2nf97zvc	205	44	2003	2003	CD
cord-026340-2nf97zvc	205	45	)	)	-RRB-
cord-026340-2nf97zvc	205	46	.	.	.
cord-026340-2nf97zvc	206	1	How	how	WRB
cord-026340-2nf97zvc	206	2	effective	effective	JJ
cord-026340-2nf97zvc	206	3	can	can	MD
cord-026340-2nf97zvc	206	4	be	be	VB
cord-026340-2nf97zvc	206	5	CQ	CQ	NNP
cord-026340-2nf97zvc	206	6	against	against	IN
cord-026340-2nf97zvc	206	7	SARS	SARS	NNP
cord-026340-2nf97zvc	206	8	?	?	.
cord-026340-2nf97zvc	207	1	In	in	IN
cord-026340-2nf97zvc	207	2	2005	2005	CD
cord-026340-2nf97zvc	207	3	,	,	,
cord-026340-2nf97zvc	207	4	Nichol	Nichol	NNP
cord-026340-2nf97zvc	207	5	et	et	NNP
cord-026340-2nf97zvc	207	6	al	al	NNP
cord-026340-2nf97zvc	207	7	.	.	NNP
cord-026340-2nf97zvc	207	8	reported	report	VBD
cord-026340-2nf97zvc	207	9	the	the	DT
cord-026340-2nf97zvc	207	10	anti	anti	JJ
cord-026340-2nf97zvc	207	11	-	-	JJ
cord-026340-2nf97zvc	207	12	viral	viral	JJ
cord-026340-2nf97zvc	207	13	effects	effect	NNS
cord-026340-2nf97zvc	207	14	against	against	IN
cord-026340-2nf97zvc	207	15	SARS	SARS	NNP
cord-026340-2nf97zvc	207	16	-	-	HYPH
cord-026340-2nf97zvc	207	17	CoV	CoV	NNP
cord-026340-2nf97zvc	207	18	infection	infection	NN
cord-026340-2nf97zvc	207	19	in	in	IN
cord-026340-2nf97zvc	207	20	primate	primate	JJ
cord-026340-2nf97zvc	207	21	Vero	Vero	NNP
cord-026340-2nf97zvc	207	22	E6	E6	NNP
cord-026340-2nf97zvc	207	23	cells	cell	NNS
cord-026340-2nf97zvc	207	24	(	(	-LRB-
cord-026340-2nf97zvc	207	25	derived	derive	VBN
cord-026340-2nf97zvc	207	26	from	from	IN
cord-026340-2nf97zvc	207	27	the	the	DT
cord-026340-2nf97zvc	207	28	African	african	JJ
cord-026340-2nf97zvc	207	29	green	green	JJ
cord-026340-2nf97zvc	207	30	monkey	monkey	NN
cord-026340-2nf97zvc	207	31	kidney	kidney	NN
cord-026340-2nf97zvc	207	32	)	)	-RRB-
cord-026340-2nf97zvc	208	1	(	(	-LRB-
cord-026340-2nf97zvc	208	2	Vincent	Vincent	NNP
cord-026340-2nf97zvc	208	3	et	et	NNP
cord-026340-2nf97zvc	208	4	al	al	NNP
cord-026340-2nf97zvc	208	5	.	.	NNP
cord-026340-2nf97zvc	208	6	2005	2005	CD
cord-026340-2nf97zvc	208	7	)	)	-RRB-
cord-026340-2nf97zvc	208	8	.	.	.
cord-026340-2nf97zvc	209	1	Thereafter	thereafter	RB
cord-026340-2nf97zvc	209	2	,	,	,
cord-026340-2nf97zvc	209	3	it	-PRON-	PRP
cord-026340-2nf97zvc	209	4	was	be	VBD
cord-026340-2nf97zvc	209	5	found	find	VBN
cord-026340-2nf97zvc	209	6	that	that	IN
cord-026340-2nf97zvc	209	7	hydroxyl	hydroxyl	NN
cord-026340-2nf97zvc	209	8	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	209	9	(	(	-LRB-
cord-026340-2nf97zvc	209	10	HCQ	HCQ	NNP
cord-026340-2nf97zvc	209	11	,	,	,
cord-026340-2nf97zvc	209	12	which	which	WDT
cord-026340-2nf97zvc	209	13	has	have	VBZ
cord-026340-2nf97zvc	209	14	40	40	CD
cord-026340-2nf97zvc	209	15	%	%	NN
cord-026340-2nf97zvc	209	16	lesser	less	JJR
cord-026340-2nf97zvc	209	17	adverse	adverse	JJ
cord-026340-2nf97zvc	209	18	effects	effect	NNS
cord-026340-2nf97zvc	209	19	than	than	IN
cord-026340-2nf97zvc	209	20	CQ	CQ	NNP
cord-026340-2nf97zvc	209	21	)	)	-RRB-
cord-026340-2nf97zvc	209	22	has	have	VBZ
cord-026340-2nf97zvc	209	23	a	a	DT
cord-026340-2nf97zvc	209	24	better	well	JJR
cord-026340-2nf97zvc	209	25	anti	anti	JJ
cord-026340-2nf97zvc	209	26	-	-	JJ
cord-026340-2nf97zvc	209	27	SARS	SARS	NNP
cord-026340-2nf97zvc	209	28	-	-	HYPH
cord-026340-2nf97zvc	209	29	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	209	30	activity	activity	NN
cord-026340-2nf97zvc	209	31	than	than	IN
cord-026340-2nf97zvc	209	32	CQ	CQ	NNP
cord-026340-2nf97zvc	209	33	in	in	IN
cord-026340-2nf97zvc	209	34	Vero	Vero	NNP
cord-026340-2nf97zvc	209	35	cells	cell	NNS
cord-026340-2nf97zvc	209	36	Liu	Liu	NNP
cord-026340-2nf97zvc	209	37	et	et	NNP
cord-026340-2nf97zvc	209	38	al	al	NNP
cord-026340-2nf97zvc	209	39	.	.	.
cord-026340-2nf97zvc	210	1	2020	2020	CD
cord-026340-2nf97zvc	210	2	;	;	:
cord-026340-2nf97zvc	210	3	Wang	Wang	NNP
cord-026340-2nf97zvc	210	4	and	and	CC
cord-026340-2nf97zvc	210	5	Cheng	Cheng	NNP
cord-026340-2nf97zvc	210	6	2020	2020	CD
cord-026340-2nf97zvc	210	7	)	)	-RRB-
cord-026340-2nf97zvc	210	8	.	.	.
cord-026340-2nf97zvc	211	1	An	an	DT
cord-026340-2nf97zvc	211	2	interesting	interesting	JJ
cord-026340-2nf97zvc	211	3	mode	mode	NN
cord-026340-2nf97zvc	211	4	of	of	IN
cord-026340-2nf97zvc	211	5	action	action	NN
cord-026340-2nf97zvc	211	6	of	of	IN
cord-026340-2nf97zvc	211	7	both	both	CC
cord-026340-2nf97zvc	211	8	CQ	CQ	NNP
cord-026340-2nf97zvc	211	9	and	and	CC
cord-026340-2nf97zvc	211	10	HCQ	HCQ	NNP
cord-026340-2nf97zvc	211	11	is	be	VBZ
cord-026340-2nf97zvc	211	12	their	-PRON-	PRP$
cord-026340-2nf97zvc	211	13	ability	ability	NN
cord-026340-2nf97zvc	211	14	to	to	TO
cord-026340-2nf97zvc	211	15	inhibit	inhibit	VB
cord-026340-2nf97zvc	211	16	binding	bind	VBG
cord-026340-2nf97zvc	211	17	of	of	IN
cord-026340-2nf97zvc	211	18	SARS	SARS	NNP
cord-026340-2nf97zvc	211	19	-	-	HYPH
cord-026340-2nf97zvc	211	20	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	211	21	viral	viral	JJ
cord-026340-2nf97zvc	211	22	particles	particle	NNS
cord-026340-2nf97zvc	211	23	to	to	IN
cord-026340-2nf97zvc	211	24	ACE2	ACE2	NNP
cord-026340-2nf97zvc	211	25	without	without	IN
cord-026340-2nf97zvc	211	26	affecting	affect	VBG
cord-026340-2nf97zvc	211	27	the	the	DT
cord-026340-2nf97zvc	211	28	cellular	cellular	JJ
cord-026340-2nf97zvc	211	29	level	level	NN
cord-026340-2nf97zvc	211	30	of	of	IN
cord-026340-2nf97zvc	211	31	ACE2	ACE2	NNP
cord-026340-2nf97zvc	211	32	expression	expression	NN
cord-026340-2nf97zvc	211	33	.	.	.
cord-026340-2nf97zvc	212	1	This	this	DT
cord-026340-2nf97zvc	212	2	was	be	VBD
cord-026340-2nf97zvc	212	3	basically	basically	RB
cord-026340-2nf97zvc	212	4	via	via	IN
cord-026340-2nf97zvc	212	5	an	an	DT
cord-026340-2nf97zvc	212	6	interference	interference	NN
cord-026340-2nf97zvc	212	7	with	with	IN
cord-026340-2nf97zvc	212	8	the	the	DT
cord-026340-2nf97zvc	212	9	glycosylation	glycosylation	NN
cord-026340-2nf97zvc	212	10	on	on	IN
cord-026340-2nf97zvc	212	11	ACE2	ACE2	NNP
cord-026340-2nf97zvc	212	12	receptor	receptor	NN
cord-026340-2nf97zvc	212	13	,	,	,
cord-026340-2nf97zvc	212	14	which	which	WDT
cord-026340-2nf97zvc	212	15	is	be	VBZ
cord-026340-2nf97zvc	212	16	required	require	VBN
cord-026340-2nf97zvc	212	17	for	for	IN
cord-026340-2nf97zvc	212	18	ligand	ligand	NN
cord-026340-2nf97zvc	212	19	recognition	recognition	NN
cord-026340-2nf97zvc	212	20	.	.	.
cord-026340-2nf97zvc	213	1	This	this	DT
cord-026340-2nf97zvc	213	2	was	be	VBD
cord-026340-2nf97zvc	213	3	ensured	ensure	VBN
cord-026340-2nf97zvc	213	4	via	via	IN
cord-026340-2nf97zvc	213	5	inhibition	inhibition	NN
cord-026340-2nf97zvc	213	6	of	of	IN
cord-026340-2nf97zvc	213	7	an	an	DT
cord-026340-2nf97zvc	213	8	enzyme	enzyme	NN
cord-026340-2nf97zvc	213	9	called	call	VBN
cord-026340-2nf97zvc	213	10	quinone	quinone	NN
cord-026340-2nf97zvc	213	11	reductase-2	reductase-2	NNP
cord-026340-2nf97zvc	213	12	which	which	WDT
cord-026340-2nf97zvc	213	13	is	be	VBZ
cord-026340-2nf97zvc	213	14	vital	vital	JJ
cord-026340-2nf97zvc	213	15	for	for	IN
cord-026340-2nf97zvc	213	16	biosynthesis	biosynthesis	NN
cord-026340-2nf97zvc	213	17	of	of	IN
cord-026340-2nf97zvc	213	18	sialic	sialic	JJ
cord-026340-2nf97zvc	213	19	acids	acid	NNS
cord-026340-2nf97zvc	213	20	and	and	CC
cord-026340-2nf97zvc	213	21	thereby	thereby	RB
cord-026340-2nf97zvc	213	22	glycosylation	glycosylation	NN
cord-026340-2nf97zvc	213	23	process	process	NN
cord-026340-2nf97zvc	213	24	.	.	.
cord-026340-2nf97zvc	214	1	ACE2	ACE2	NNP
cord-026340-2nf97zvc	214	2	when	when	WRB
cord-026340-2nf97zvc	214	3	not	not	RB
cord-026340-2nf97zvc	214	4	in	in	IN
cord-026340-2nf97zvc	214	5	the	the	DT
cord-026340-2nf97zvc	214	6	glycosylated	glycosylated	JJ
cord-026340-2nf97zvc	214	7	state	state	NN
cord-026340-2nf97zvc	214	8	is	be	VBZ
cord-026340-2nf97zvc	214	9	less	less	RBR
cord-026340-2nf97zvc	214	10	efficient	efficient	JJ
cord-026340-2nf97zvc	214	11	to	to	TO
cord-026340-2nf97zvc	214	12	interact	interact	VB
cord-026340-2nf97zvc	214	13	with	with	IN
cord-026340-2nf97zvc	214	14	the	the	DT
cord-026340-2nf97zvc	214	15	SARS	SARS	NNP
cord-026340-2nf97zvc	214	16	-	-	HYPH
cord-026340-2nf97zvc	214	17	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	214	18	spike	spike	NN
cord-026340-2nf97zvc	214	19	protein	protein	NN
cord-026340-2nf97zvc	214	20	and	and	CC
cord-026340-2nf97zvc	214	21	is	be	VBZ
cord-026340-2nf97zvc	214	22	one	one	CD
cord-026340-2nf97zvc	214	23	of	of	IN
cord-026340-2nf97zvc	214	24	the	the	DT
cord-026340-2nf97zvc	214	25	best	good	JJS
cord-026340-2nf97zvc	214	26	ways	way	NNS
cord-026340-2nf97zvc	214	27	to	to	TO
cord-026340-2nf97zvc	214	28	inhibit	inhibit	VB
cord-026340-2nf97zvc	214	29	viral	viral	JJ
cord-026340-2nf97zvc	214	30	entry	entry	NN
cord-026340-2nf97zvc	214	31	(	(	-LRB-
cord-026340-2nf97zvc	214	32	Vincent	Vincent	NNP
cord-026340-2nf97zvc	214	33	et	et	NNP
cord-026340-2nf97zvc	214	34	al	al	NNP
cord-026340-2nf97zvc	214	35	.	.	NNP
cord-026340-2nf97zvc	214	36	2005	2005	CD
cord-026340-2nf97zvc	214	37	;	;	:
cord-026340-2nf97zvc	214	38	Wang	Wang	NNP
cord-026340-2nf97zvc	214	39	and	and	CC
cord-026340-2nf97zvc	214	40	Cheng	Cheng	NNP
cord-026340-2nf97zvc	214	41	2020	2020	CD
cord-026340-2nf97zvc	214	42	)	)	-RRB-
cord-026340-2nf97zvc	214	43	.	.	.
cord-026340-2nf97zvc	215	1	CQ	CQ	NNP
cord-026340-2nf97zvc	215	2	and	and	CC
cord-026340-2nf97zvc	215	3	HCQ	HCQ	NNP
cord-026340-2nf97zvc	215	4	also	also	RB
cord-026340-2nf97zvc	215	5	have	have	VBP
cord-026340-2nf97zvc	215	6	a	a	DT
cord-026340-2nf97zvc	215	7	track	track	NN
cord-026340-2nf97zvc	215	8	record	record	NN
cord-026340-2nf97zvc	215	9	of	of	IN
cord-026340-2nf97zvc	215	10	reducing	reduce	VBG
cord-026340-2nf97zvc	215	11	over	over	IN
cord-026340-2nf97zvc	215	12	-	-	HYPH
cord-026340-2nf97zvc	215	13	production	production	NN
cord-026340-2nf97zvc	215	14	of	of	IN
cord-026340-2nf97zvc	215	15	cytokines	cytokine	NNS
cord-026340-2nf97zvc	215	16	during	during	IN
cord-026340-2nf97zvc	215	17	rheumatoid	rheumatoid	NN
cord-026340-2nf97zvc	215	18	arthritis	arthritis	NN
cord-026340-2nf97zvc	215	19	,	,	,
cord-026340-2nf97zvc	215	20	lupus	lupus	NN
cord-026340-2nf97zvc	215	21	erythematosus	erythematosus	NN
cord-026340-2nf97zvc	215	22	,	,	,
cord-026340-2nf97zvc	215	23	and	and	CC
cord-026340-2nf97zvc	215	24	sarcoidosis	sarcoidosis	NN
cord-026340-2nf97zvc	216	1	(	(	-LRB-
cord-026340-2nf97zvc	216	2	Rebecca	Rebecca	NNP
cord-026340-2nf97zvc	216	3	et	et	NNP
cord-026340-2nf97zvc	216	4	al	al	NNP
cord-026340-2nf97zvc	216	5	.	.	.
cord-026340-2nf97zvc	217	1	2019	2019	CD
cord-026340-2nf97zvc	217	2	;	;	:
cord-026340-2nf97zvc	217	3	Schrezenmeier	Schrezenmeier	NNP
cord-026340-2nf97zvc	217	4	and	and	CC
cord-026340-2nf97zvc	217	5	Dörner	Dörner	NNP
cord-026340-2nf97zvc	217	6	2020	2020	CD
cord-026340-2nf97zvc	217	7	)	)	-RRB-
cord-026340-2nf97zvc	217	8	.	.	.
cord-026340-2nf97zvc	218	1	These	these	DT
cord-026340-2nf97zvc	218	2	immunomodulatory	immunomodulatory	JJ
cord-026340-2nf97zvc	218	3	effects	effect	NNS
cord-026340-2nf97zvc	218	4	of	of	IN
cord-026340-2nf97zvc	218	5	CQ	CQ	NNP
cord-026340-2nf97zvc	218	6	and	and	CC
cord-026340-2nf97zvc	218	7	HCQ	HCQ	NNP
cord-026340-2nf97zvc	218	8	need	need	VB
cord-026340-2nf97zvc	218	9	highlight	highlight	NN
cord-026340-2nf97zvc	218	10	since	since	IN
cord-026340-2nf97zvc	218	11	they	-PRON-	PRP
cord-026340-2nf97zvc	218	12	may	may	MD
cord-026340-2nf97zvc	218	13	be	be	VB
cord-026340-2nf97zvc	218	14	useful	useful	JJ
cord-026340-2nf97zvc	218	15	for	for	IN
cord-026340-2nf97zvc	218	16	taming	tame	VBG
cord-026340-2nf97zvc	218	17	the	the	DT
cord-026340-2nf97zvc	218	18	cytokine	cytokine	NN
cord-026340-2nf97zvc	218	19	storm	storm	NN
cord-026340-2nf97zvc	218	20	in	in	IN
cord-026340-2nf97zvc	218	21	the	the	DT
cord-026340-2nf97zvc	218	22	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	218	23	scenario	scenario	NN
cord-026340-2nf97zvc	218	24	(	(	-LRB-
cord-026340-2nf97zvc	218	25	Conti	Conti	NNP
cord-026340-2nf97zvc	218	26	et	et	NNP
cord-026340-2nf97zvc	218	27	al	al	NNP
cord-026340-2nf97zvc	218	28	.	.	NNP
cord-026340-2nf97zvc	218	29	2020	2020	CD
cord-026340-2nf97zvc	218	30	)	)	-RRB-
cord-026340-2nf97zvc	218	31	.	.	.
cord-026340-2nf97zvc	219	1	One	one	CD
cord-026340-2nf97zvc	219	2	of	of	IN
cord-026340-2nf97zvc	219	3	the	the	DT
cord-026340-2nf97zvc	219	4	proposed	propose	VBN
cord-026340-2nf97zvc	219	5	modulatory	modulatory	JJ
cord-026340-2nf97zvc	219	6	effect	effect	NN
cord-026340-2nf97zvc	219	7	of	of	IN
cord-026340-2nf97zvc	219	8	HCQ	HCQ	NNP
cord-026340-2nf97zvc	219	9	is	be	VBZ
cord-026340-2nf97zvc	219	10	its	-PRON-	PRP$
cord-026340-2nf97zvc	219	11	ability	ability	NN
cord-026340-2nf97zvc	219	12	to	to	TO
cord-026340-2nf97zvc	219	13	inhibit	inhibit	VB
cord-026340-2nf97zvc	219	14	the	the	DT
cord-026340-2nf97zvc	219	15	activity	activity	NN
cord-026340-2nf97zvc	219	16	of	of	IN
cord-026340-2nf97zvc	219	17	the	the	DT
cord-026340-2nf97zvc	219	18	nucleic	nucleic	JJ
cord-026340-2nf97zvc	219	19	acid	acid	NN
cord-026340-2nf97zvc	219	20	sensor	sensor	NN
cord-026340-2nf97zvc	219	21	cyclic	cyclic	JJ
cord-026340-2nf97zvc	219	22	GMP	GMP	NNP
cord-026340-2nf97zvc	219	23	-	-	HYPH
cord-026340-2nf97zvc	219	24	AMP	AMP	NNP
cord-026340-2nf97zvc	219	25	(	(	-LRB-
cord-026340-2nf97zvc	219	26	cGAMP	cGAMP	NNP
cord-026340-2nf97zvc	219	27	)	)	-RRB-
cord-026340-2nf97zvc	219	28	synthase	synthase	NN
cord-026340-2nf97zvc	219	29	(	(	-LRB-
cord-026340-2nf97zvc	219	30	cGAS	cgas	NN
cord-026340-2nf97zvc	219	31	)	)	-RRB-
cord-026340-2nf97zvc	219	32	by	by	IN
cord-026340-2nf97zvc	219	33	interfering	interfere	VBG
cord-026340-2nf97zvc	219	34	with	with	IN
cord-026340-2nf97zvc	219	35	its	-PRON-	PRP$
cord-026340-2nf97zvc	219	36	binding	binding	NN
cord-026340-2nf97zvc	219	37	to	to	IN
cord-026340-2nf97zvc	219	38	cytosolic	cytosolic	JJ
cord-026340-2nf97zvc	219	39	DNA	dna	NN
cord-026340-2nf97zvc	219	40	,	,	,
cord-026340-2nf97zvc	219	41	and	and	CC
cord-026340-2nf97zvc	219	42	by	by	IN
cord-026340-2nf97zvc	219	43	stopping	stop	VBG
cord-026340-2nf97zvc	219	44	TLR	TLR	NNP
cord-026340-2nf97zvc	219	45	signaling	signal	VBG
cord-026340-2nf97zvc	219	46	and	and	CC
cord-026340-2nf97zvc	219	47	cGAS	cgas	NN
cord-026340-2nf97zvc	219	48	-	-	HYPH
cord-026340-2nf97zvc	219	49	stimulator	stimulator	NN
cord-026340-2nf97zvc	219	50	of	of	IN
cord-026340-2nf97zvc	219	51	interferon	interferon	NN
cord-026340-2nf97zvc	219	52	genes	gene	NNS
cord-026340-2nf97zvc	219	53	(	(	-LRB-
cord-026340-2nf97zvc	219	54	STING	sting	NN
cord-026340-2nf97zvc	219	55	)	)	-RRB-
cord-026340-2nf97zvc	219	56	signaling	signal	VBG
cord-026340-2nf97zvc	219	57	(	(	-LRB-
cord-026340-2nf97zvc	219	58	Picot	Picot	NNP
cord-026340-2nf97zvc	219	59	2020	2020	CD
cord-026340-2nf97zvc	219	60	)	)	-RRB-
cord-026340-2nf97zvc	219	61	.	.	.
cord-026340-2nf97zvc	220	1	At	at	IN
cord-026340-2nf97zvc	220	2	the	the	DT
cord-026340-2nf97zvc	220	3	cellular	cellular	JJ
cord-026340-2nf97zvc	220	4	level	level	NN
cord-026340-2nf97zvc	220	5	,	,	,
cord-026340-2nf97zvc	220	6	CQ	CQ	NNP
cord-026340-2nf97zvc	220	7	and	and	CC
cord-026340-2nf97zvc	220	8	HCQ	HCQ	NNP
cord-026340-2nf97zvc	220	9	have	have	VBP
cord-026340-2nf97zvc	220	10	been	be	VBN
cord-026340-2nf97zvc	220	11	shown	show	VBN
cord-026340-2nf97zvc	220	12	to	to	TO
cord-026340-2nf97zvc	220	13	inhibit	inhibit	VB
cord-026340-2nf97zvc	220	14	immune	immune	JJ
cord-026340-2nf97zvc	220	15	activation	activation	NN
cord-026340-2nf97zvc	220	16	by	by	IN
cord-026340-2nf97zvc	220	17	reducing	reduce	VBG
cord-026340-2nf97zvc	220	18	signaling	signaling	NN
cord-026340-2nf97zvc	220	19	by	by	IN
cord-026340-2nf97zvc	220	20	Pattern	Pattern	NNP
cord-026340-2nf97zvc	220	21	Recognition	Recognition	NNP
cord-026340-2nf97zvc	220	22	Receptors	Receptors	NNPS
cord-026340-2nf97zvc	220	23	(	(	-LRB-
cord-026340-2nf97zvc	220	24	Toll	Toll	NNP
cord-026340-2nf97zvc	220	25	-	-	HYPH
cord-026340-2nf97zvc	220	26	like	like	JJ
cord-026340-2nf97zvc	220	27	receptor	receptor	NN
cord-026340-2nf97zvc	220	28	signaling	signaling	NN
cord-026340-2nf97zvc	220	29	)	)	-RRB-
cord-026340-2nf97zvc	220	30	and	and	CC
cord-026340-2nf97zvc	220	31	cytokine	cytokine	JJ
cord-026340-2nf97zvc	220	32	production	production	NN
cord-026340-2nf97zvc	220	33	.	.	.
cord-026340-2nf97zvc	221	1	Both	both	DT
cord-026340-2nf97zvc	221	2	CQ	CQ	NNP
cord-026340-2nf97zvc	221	3	and	and	CC
cord-026340-2nf97zvc	221	4	HCQ	HCQ	NNP
cord-026340-2nf97zvc	221	5	reduce	reduce	VB
cord-026340-2nf97zvc	221	6	the	the	DT
cord-026340-2nf97zvc	221	7	secretion	secretion	NN
cord-026340-2nf97zvc	221	8	of	of	IN
cord-026340-2nf97zvc	221	9	pro	pro	JJ
cord-026340-2nf97zvc	221	10	-	-	JJ
cord-026340-2nf97zvc	221	11	inflammatory	inflammatory	JJ
cord-026340-2nf97zvc	221	12	cytokines	cytokine	NNS
cord-026340-2nf97zvc	221	13	and	and	CC
cord-026340-2nf97zvc	221	14	,	,	,
cord-026340-2nf97zvc	221	15	in	in	IN
cord-026340-2nf97zvc	221	16	particular	particular	JJ
cord-026340-2nf97zvc	221	17	,	,	,
cord-026340-2nf97zvc	221	18	TNF	TNF	NNP
cord-026340-2nf97zvc	221	19	-	-	HYPH
cord-026340-2nf97zvc	221	20	α	α	NNP
cord-026340-2nf97zvc	221	21	in	in	IN
cord-026340-2nf97zvc	221	22	macrophages	macrophage	NNS
cord-026340-2nf97zvc	221	23	.	.	.
cord-026340-2nf97zvc	222	1	Different	different	JJ
cord-026340-2nf97zvc	222	2	mechanisms	mechanism	NNS
cord-026340-2nf97zvc	222	3	have	have	VBP
cord-026340-2nf97zvc	222	4	been	be	VBN
cord-026340-2nf97zvc	222	5	proposed	propose	VBN
cord-026340-2nf97zvc	222	6	to	to	TO
cord-026340-2nf97zvc	222	7	explain	explain	VB
cord-026340-2nf97zvc	222	8	the	the	DT
cord-026340-2nf97zvc	222	9	reduction	reduction	NN
cord-026340-2nf97zvc	222	10	in	in	IN
cord-026340-2nf97zvc	222	11	TNF	TNF	NNP
cord-026340-2nf97zvc	222	12	-	-	HYPH
cord-026340-2nf97zvc	222	13	α	α	NNP
cord-026340-2nf97zvc	222	14	by	by	IN
cord-026340-2nf97zvc	222	15	CQ	CQ	NNP
cord-026340-2nf97zvc	222	16	and	and	CC
cord-026340-2nf97zvc	222	17	HCQ	HCQ	NNP
cord-026340-2nf97zvc	222	18	like	like	IN
cord-026340-2nf97zvc	222	19	(	(	-LRB-
cord-026340-2nf97zvc	222	20	i	i	NN
cord-026340-2nf97zvc	222	21	)	)	-RRB-
cord-026340-2nf97zvc	222	22	inhibition	inhibition	NN
cord-026340-2nf97zvc	222	23	of	of	IN
cord-026340-2nf97zvc	222	24	TNF	TNF	NNP
cord-026340-2nf97zvc	222	25	-	-	HYPH
cord-026340-2nf97zvc	222	26	α	α	NNP
cord-026340-2nf97zvc	222	27	mRNA	mrna	NN
cord-026340-2nf97zvc	222	28	expression	expression	NN
cord-026340-2nf97zvc	222	29	,	,	,
cord-026340-2nf97zvc	222	30	(	(	-LRB-
cord-026340-2nf97zvc	222	31	ii	ii	NN
cord-026340-2nf97zvc	222	32	)	)	-RRB-
cord-026340-2nf97zvc	222	33	inhibition	inhibition	NN
cord-026340-2nf97zvc	222	34	in	in	IN
cord-026340-2nf97zvc	222	35	posttranslational	posttranslational	JJ
cord-026340-2nf97zvc	222	36	conversion	conversion	NN
cord-026340-2nf97zvc	222	37	of	of	IN
cord-026340-2nf97zvc	222	38	pro	pro	JJ
cord-026340-2nf97zvc	222	39	-	-	JJ
cord-026340-2nf97zvc	222	40	TNFα	TNFα	NNS
cord-026340-2nf97zvc	222	41	to	to	IN
cord-026340-2nf97zvc	222	42	a	a	DT
cord-026340-2nf97zvc	222	43	soluble	soluble	JJ
cord-026340-2nf97zvc	222	44	mature	mature	JJ
cord-026340-2nf97zvc	222	45	form	form	NN
cord-026340-2nf97zvc	222	46	,	,	,
cord-026340-2nf97zvc	222	47	(	(	-LRB-
cord-026340-2nf97zvc	222	48	iii	iii	NN
cord-026340-2nf97zvc	222	49	)	)	-RRB-
cord-026340-2nf97zvc	222	50	a	a	DT
cord-026340-2nf97zvc	222	51	pre	pre	JJ
cord-026340-2nf97zvc	222	52	-	-	JJ
cord-026340-2nf97zvc	222	53	translational	translational	JJ
cord-026340-2nf97zvc	222	54	stage	stage	NN
cord-026340-2nf97zvc	222	55	by	by	IN
cord-026340-2nf97zvc	222	56	a	a	DT
cord-026340-2nf97zvc	222	57	non	non	JJ
cord-026340-2nf97zvc	222	58	-	-	JJ
cord-026340-2nf97zvc	222	59	lysosomotropic	lysosomotropic	JJ
cord-026340-2nf97zvc	222	60	mechanism	mechanism	NN
cord-026340-2nf97zvc	222	61	and	and	CC
cord-026340-2nf97zvc	222	62	(	(	-LRB-
cord-026340-2nf97zvc	222	63	iv	iv	LS
cord-026340-2nf97zvc	222	64	)	)	-RRB-
cord-026340-2nf97zvc	222	65	reduced	reduce	VBN
cord-026340-2nf97zvc	222	66	surface	surface	NN
cord-026340-2nf97zvc	222	67	expression	expression	NN
cord-026340-2nf97zvc	222	68	of	of	IN
cord-026340-2nf97zvc	222	69	TNF	TNF	NNP
cord-026340-2nf97zvc	222	70	-	-	HYPH
cord-026340-2nf97zvc	222	71	α	α	NNP
cord-026340-2nf97zvc	222	72	receptors	receptor	NNS
cord-026340-2nf97zvc	222	73	.	.	.
cord-026340-2nf97zvc	223	1	Apart	apart	RB
cord-026340-2nf97zvc	223	2	from	from	IN
cord-026340-2nf97zvc	223	3	TNF	TNF	NNP
cord-026340-2nf97zvc	223	4	-	-	HYPH
cord-026340-2nf97zvc	223	5	α	α	NNP
cord-026340-2nf97zvc	223	6	,	,	,
cord-026340-2nf97zvc	223	7	CQ	CQ	NNP
cord-026340-2nf97zvc	223	8	also	also	RB
cord-026340-2nf97zvc	223	9	suppresses	suppress	VBZ
cord-026340-2nf97zvc	223	10	cytokines	cytokine	NNS
cord-026340-2nf97zvc	223	11	like	like	IN
cord-026340-2nf97zvc	223	12	IL-1	IL-1	NNP
cord-026340-2nf97zvc	223	13	,	,	,
cord-026340-2nf97zvc	223	14	IL-6	IL-6	NNP
cord-026340-2nf97zvc	223	15	and	and	CC
cord-026340-2nf97zvc	223	16	IFNγ	IFNγ	NNS
cord-026340-2nf97zvc	223	17	in	in	IN
cord-026340-2nf97zvc	223	18	mononuclear	mononuclear	JJ
cord-026340-2nf97zvc	223	19	cells	cell	NNS
cord-026340-2nf97zvc	223	20	,	,	,
cord-026340-2nf97zvc	223	21	again	again	RB
cord-026340-2nf97zvc	223	22	by	by	IN
cord-026340-2nf97zvc	223	23	modulating	modulate	VBG
cord-026340-2nf97zvc	223	24	TLR	TLR	NNP
cord-026340-2nf97zvc	223	25	(	(	-LRB-
cord-026340-2nf97zvc	223	26	Totura	Totura	NNP
cord-026340-2nf97zvc	223	27	et	et	FW
cord-026340-2nf97zvc	223	28	al	al	NNP
cord-026340-2nf97zvc	223	29	.	.	.
cord-026340-2nf97zvc	223	30	2015	2015	CD
cord-026340-2nf97zvc	223	31	;	;	:
cord-026340-2nf97zvc	223	32	Lester	Lester	NNP
cord-026340-2nf97zvc	223	33	and	and	CC
cord-026340-2nf97zvc	223	34	Li	Li	NNP
cord-026340-2nf97zvc	223	35	2014	2014	CD
cord-026340-2nf97zvc	223	36	;	;	:
cord-026340-2nf97zvc	223	37	Conti	Conti	NNP
cord-026340-2nf97zvc	223	38	et	et	NNP
cord-026340-2nf97zvc	223	39	al	al	NNP
cord-026340-2nf97zvc	223	40	.	.	NNP
cord-026340-2nf97zvc	223	41	2020	2020	CD
cord-026340-2nf97zvc	223	42	)	)	-RRB-
cord-026340-2nf97zvc	223	43	.	.	.
cord-026340-2nf97zvc	224	1	In	in	IN
cord-026340-2nf97zvc	224	2	light	light	NN
cord-026340-2nf97zvc	224	3	of	of	IN
cord-026340-2nf97zvc	224	4	the	the	DT
cord-026340-2nf97zvc	224	5	available	available	JJ
cord-026340-2nf97zvc	224	6	references	reference	NNS
cord-026340-2nf97zvc	224	7	,	,	,
cord-026340-2nf97zvc	224	8	the	the	DT
cord-026340-2nf97zvc	224	9	plausible	plausible	JJ
cord-026340-2nf97zvc	224	10	interferences	interference	NNS
cord-026340-2nf97zvc	224	11	by	by	IN
cord-026340-2nf97zvc	224	12	CQ	CQ	NNP
cord-026340-2nf97zvc	224	13	or	or	CC
cord-026340-2nf97zvc	224	14	HCQ	HCQ	NNP
cord-026340-2nf97zvc	224	15	are	be	VBP
cord-026340-2nf97zvc	224	16	depicted	depict	VBN
cord-026340-2nf97zvc	224	17	in	in	IN
cord-026340-2nf97zvc	224	18	Fig	Fig	NNP
cord-026340-2nf97zvc	224	19	.	.	.
cord-026340-2nf97zvc	225	1	1	1	LS
cord-026340-2nf97zvc	225	2	.	.	.
cord-026340-2nf97zvc	226	1	Interference	interference	NN
cord-026340-2nf97zvc	226	2	of	of	IN
cord-026340-2nf97zvc	226	3	virus	virus	NN
cord-026340-2nf97zvc	226	4	binding	bind	VBG
cord-026340-2nf97zvc	226	5	to	to	IN
cord-026340-2nf97zvc	226	6	host	host	VB
cord-026340-2nf97zvc	226	7	cell	cell	NN
cord-026340-2nf97zvc	226	8	:	:	:
cord-026340-2nf97zvc	226	9	(	(	-LRB-
cord-026340-2nf97zvc	226	10	i	i	NN
cord-026340-2nf97zvc	226	11	)	)	-RRB-
cord-026340-2nf97zvc	227	1	The	the	DT
cord-026340-2nf97zvc	227	2	drug	drug	NN
cord-026340-2nf97zvc	227	3	(	(	-LRB-
cord-026340-2nf97zvc	227	4	CQ	CQ	NNP
cord-026340-2nf97zvc	227	5	or	or	CC
cord-026340-2nf97zvc	227	6	HCQ	HCQ	NNP
cord-026340-2nf97zvc	227	7	)	)	-RRB-
cord-026340-2nf97zvc	227	8	interferes	interfere	VBZ
cord-026340-2nf97zvc	227	9	with	with	IN
cord-026340-2nf97zvc	227	10	ACE2	ACE2	NNP
cord-026340-2nf97zvc	227	11	receptor	receptor	NN
cord-026340-2nf97zvc	227	12	glycosylation	glycosylation	NN
cord-026340-2nf97zvc	227	13	preventing	prevent	VBG
cord-026340-2nf97zvc	227	14	SARS	SARS	NNP
cord-026340-2nf97zvc	227	15	-	-	HYPH
cord-026340-2nf97zvc	227	16	CoV2	cov2	NN
cord-026340-2nf97zvc	227	17	binding	bind	VBG
cord-026340-2nf97zvc	227	18	to	to	TO
cord-026340-2nf97zvc	227	19	target	target	NN
cord-026340-2nf97zvc	227	20	cells	cell	NNS
cord-026340-2nf97zvc	227	21	.	.	.
cord-026340-2nf97zvc	228	1	(	(	-LRB-
cord-026340-2nf97zvc	228	2	ii	ii	LS
cord-026340-2nf97zvc	228	3	)	)	-RRB-
cord-026340-2nf97zvc	228	4	Drug	drug	NN
cord-026340-2nf97zvc	228	5	limits	limit	VBZ
cord-026340-2nf97zvc	228	6	the	the	DT
cord-026340-2nf97zvc	228	7	biosynthesis	biosynthesis	NN
cord-026340-2nf97zvc	228	8	of	of	IN
cord-026340-2nf97zvc	228	9	sialic	sialic	JJ
cord-026340-2nf97zvc	228	10	acids	acid	NNS
cord-026340-2nf97zvc	228	11	required	require	VBN
cord-026340-2nf97zvc	228	12	for	for	IN
cord-026340-2nf97zvc	228	13	cell	cell	NN
cord-026340-2nf97zvc	228	14	surface	surface	NN
cord-026340-2nf97zvc	228	15	binding	binding	NN
cord-026340-2nf97zvc	228	16	of	of	IN
cord-026340-2nf97zvc	228	17	SARS	SARS	NNP
cord-026340-2nf97zvc	228	18	-	-	HYPH
cord-026340-2nf97zvc	228	19	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	228	20	(	(	-LRB-
cord-026340-2nf97zvc	228	21	II	II	NNP
cord-026340-2nf97zvc	228	22	)	)	-RRB-
cord-026340-2nf97zvc	228	23	Interference	interference	NN
cord-026340-2nf97zvc	228	24	in	in	IN
cord-026340-2nf97zvc	228	25	viral	viral	JJ
cord-026340-2nf97zvc	228	26	transport	transport	NN
cord-026340-2nf97zvc	228	27	:	:	:
cord-026340-2nf97zvc	229	1	Drug	drug	NN
cord-026340-2nf97zvc	229	2	modulates	modulate	VBZ
cord-026340-2nf97zvc	229	3	the	the	DT
cord-026340-2nf97zvc	229	4	acidification	acidification	NN
cord-026340-2nf97zvc	229	5	of	of	IN
cord-026340-2nf97zvc	229	6	endosomes	endosome	NNS
cord-026340-2nf97zvc	229	7	thereby	thereby	RB
cord-026340-2nf97zvc	229	8	inhibiting	inhibit	VBG
cord-026340-2nf97zvc	229	9	transport	transport	NN
cord-026340-2nf97zvc	229	10	and	and	CC
cord-026340-2nf97zvc	229	11	formation	formation	NN
cord-026340-2nf97zvc	229	12	of	of	IN
cord-026340-2nf97zvc	229	13	the	the	DT
cord-026340-2nf97zvc	229	14	autophagosome	autophagosome	NNP
cord-026340-2nf97zvc	230	1	(	(	-LRB-
cord-026340-2nf97zvc	230	2	Yang	Yang	NNP
cord-026340-2nf97zvc	230	3	et	et	NNP
cord-026340-2nf97zvc	230	4	al	al	NNP
cord-026340-2nf97zvc	230	5	.	.	.
cord-026340-2nf97zvc	231	1	2004	2004	CD
cord-026340-2nf97zvc	231	2	)	)	-RRB-
cord-026340-2nf97zvc	232	1	(	(	-LRB-
cord-026340-2nf97zvc	232	2	III	III	NNP
cord-026340-2nf97zvc	232	3	)	)	-RRB-
cord-026340-2nf97zvc	232	4	Interference	interference	NN
cord-026340-2nf97zvc	232	5	in	in	IN
cord-026340-2nf97zvc	232	6	viral	viral	JJ
cord-026340-2nf97zvc	232	7	envelope	envelope	NN
cord-026340-2nf97zvc	232	8	formation	formation	NN
cord-026340-2nf97zvc	232	9	:	:	:
cord-026340-2nf97zvc	233	1	Drug	drug	NN
cord-026340-2nf97zvc	233	2	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	233	3	the	the	DT
cord-026340-2nf97zvc	233	4	cathepsin	cathepsin	NN
cord-026340-2nf97zvc	233	5	activity	activity	NN
cord-026340-2nf97zvc	233	6	in	in	IN
cord-026340-2nf97zvc	233	7	early	early	JJ
cord-026340-2nf97zvc	233	8	endosome	endosome	NN
cord-026340-2nf97zvc	233	9	of	of	IN
cord-026340-2nf97zvc	233	10	host	host	NN
cord-026340-2nf97zvc	233	11	by	by	IN
cord-026340-2nf97zvc	233	12	increasing	increase	VBG
cord-026340-2nf97zvc	233	13	endosomal	endosomal	NNP
cord-026340-2nf97zvc	233	14	pH	pH	NNP
cord-026340-2nf97zvc	233	15	which	which	WDT
cord-026340-2nf97zvc	233	16	further	further	RB
cord-026340-2nf97zvc	233	17	blocks	block	VBZ
cord-026340-2nf97zvc	233	18	cleavage	cleavage	NN
cord-026340-2nf97zvc	233	19	of	of	IN
cord-026340-2nf97zvc	233	20	virus	virus	NN
cord-026340-2nf97zvc	233	21	envelops	envelop	VBZ
cord-026340-2nf97zvc	233	22	S	S	NNP
cord-026340-2nf97zvc	233	23	protein	protein	NN
cord-026340-2nf97zvc	233	24	leading	lead	VBG
cord-026340-2nf97zvc	233	25	to	to	TO
cord-026340-2nf97zvc	233	26	stop	stop	VB
cord-026340-2nf97zvc	233	27	fusion	fusion	NN
cord-026340-2nf97zvc	233	28	of	of	IN
cord-026340-2nf97zvc	233	29	the	the	DT
cord-026340-2nf97zvc	233	30	viral	viral	JJ
cord-026340-2nf97zvc	233	31	envelope	envelope	NN
cord-026340-2nf97zvc	233	32	(	(	-LRB-
cord-026340-2nf97zvc	233	33	Wang	Wang	NNP
cord-026340-2nf97zvc	233	34	et	et	NNP
cord-026340-2nf97zvc	233	35	al	al	NNP
cord-026340-2nf97zvc	233	36	.	.	.
cord-026340-2nf97zvc	234	1	2008	2008	CD
cord-026340-2nf97zvc	234	2	,	,	,
cord-026340-2nf97zvc	234	3	Cassell	Cassell	NNP
cord-026340-2nf97zvc	234	4	et	et	NNP
cord-026340-2nf97zvc	234	5	al	al	NNP
cord-026340-2nf97zvc	234	6	.	.	.
cord-026340-2nf97zvc	234	7	1984	1984	CD
cord-026340-2nf97zvc	234	8	)	)	-RRB-
cord-026340-2nf97zvc	235	1	(	(	-LRB-
cord-026340-2nf97zvc	235	2	IV	IV	NNP
cord-026340-2nf97zvc	235	3	)	)	-RRB-
cord-026340-2nf97zvc	235	4	Interference	interference	NN
cord-026340-2nf97zvc	235	5	to	to	IN
cord-026340-2nf97zvc	235	6	mitogen	mitogen	NN
cord-026340-2nf97zvc	235	7	-	-	HYPH
cord-026340-2nf97zvc	235	8	activated	activate	VBN
cord-026340-2nf97zvc	235	9	protein	protein	NN
cord-026340-2nf97zvc	235	10	(	(	-LRB-
cord-026340-2nf97zvc	235	11	MAP	MAP	NNP
cord-026340-2nf97zvc	235	12	)	)	-RRB-
cord-026340-2nf97zvc	236	1	kinase	kinase	NNP
cord-026340-2nf97zvc	236	2	pathway	pathway	NNP
cord-026340-2nf97zvc	236	3	:	:	:
cord-026340-2nf97zvc	237	1	By	by	IN
cord-026340-2nf97zvc	237	2	modulating	modulate	VBG
cord-026340-2nf97zvc	237	3	cellular	cellular	JJ
cord-026340-2nf97zvc	237	4	mitogenactivated	mitogenactivated	JJ
cord-026340-2nf97zvc	237	5	protein	protein	NN
cord-026340-2nf97zvc	237	6	(	(	-LRB-
cord-026340-2nf97zvc	237	7	MAP	MAP	NNP
cord-026340-2nf97zvc	237	8	)	)	-RRB-
cord-026340-2nf97zvc	238	1	kinase	kinase	NNP
cord-026340-2nf97zvc	238	2	activation	activation	NNP
cord-026340-2nf97zvc	239	1	,	,	,
cord-026340-2nf97zvc	239	2	HCQ	HCQ	NNP
cord-026340-2nf97zvc	239	3	may	may	MD
cord-026340-2nf97zvc	239	4	also	also	RB
cord-026340-2nf97zvc	239	5	inhibit	inhibit	VB
cord-026340-2nf97zvc	239	6	virus	virus	NN
cord-026340-2nf97zvc	239	7	replication	replication	NN
cord-026340-2nf97zvc	239	8	(	(	-LRB-
cord-026340-2nf97zvc	239	9	Savarino	Savarino	NNP
cord-026340-2nf97zvc	239	10	et	et	NNP
cord-026340-2nf97zvc	239	11	al	al	NNP
cord-026340-2nf97zvc	239	12	.	.	NNP
cord-026340-2nf97zvc	239	13	2003	2003	CD
cord-026340-2nf97zvc	239	14	)	)	-RRB-
cord-026340-2nf97zvc	240	1	(	(	-LRB-
cord-026340-2nf97zvc	240	2	V	v	NN
cord-026340-2nf97zvc	240	3	)	)	-RRB-
cord-026340-2nf97zvc	240	4	Modulating	modulate	VBG
cord-026340-2nf97zvc	240	5	M	M	NNP
cord-026340-2nf97zvc	240	6	protein	protein	NN
cord-026340-2nf97zvc	240	7	:	:	:
cord-026340-2nf97zvc	240	8	HCQ	HCQ	NNP
cord-026340-2nf97zvc	240	9	may	may	MD
cord-026340-2nf97zvc	240	10	alter	alter	VB
cord-026340-2nf97zvc	240	11	M	M	NNP
cord-026340-2nf97zvc	240	12	protein	protein	NN
cord-026340-2nf97zvc	240	13	maturation	maturation	NN
cord-026340-2nf97zvc	240	14	and	and	CC
cord-026340-2nf97zvc	240	15	interfere	interfere	VB
cord-026340-2nf97zvc	240	16	with	with	IN
cord-026340-2nf97zvc	240	17	virion	virion	NN
cord-026340-2nf97zvc	240	18	assembly	assembly	NN
cord-026340-2nf97zvc	240	19	and	and	CC
cord-026340-2nf97zvc	240	20	budding	budding	JJ
cord-026340-2nf97zvc	240	21	(	(	-LRB-
cord-026340-2nf97zvc	240	22	Prajapat	Prajapat	NNP
cord-026340-2nf97zvc	240	23	et	et	NNP
cord-026340-2nf97zvc	240	24	al	al	NNP
cord-026340-2nf97zvc	240	25	.	.	NNP
cord-026340-2nf97zvc	240	26	2020	2020	CD
cord-026340-2nf97zvc	240	27	)	)	-RRB-
cord-026340-2nf97zvc	241	1	(	(	-LRB-
cord-026340-2nf97zvc	241	2	VI	VI	NNP
cord-026340-2nf97zvc	241	3	)	)	-RRB-
cord-026340-2nf97zvc	241	4	Interference	interference	NN
cord-026340-2nf97zvc	241	5	to	to	IN
cord-026340-2nf97zvc	241	6	TLR	TLR	NNP
cord-026340-2nf97zvc	241	7	signaling	signal	VBG
cord-026340-2nf97zvc	241	8	pathway	pathway	NN
cord-026340-2nf97zvc	241	9	:	:	:
cord-026340-2nf97zvc	241	10	Elevation	elevation	NN
cord-026340-2nf97zvc	241	11	of	of	IN
cord-026340-2nf97zvc	241	12	endosomal	endosomal	NNP
cord-026340-2nf97zvc	241	13	pH	pH	NNP
cord-026340-2nf97zvc	241	14	by	by	IN
cord-026340-2nf97zvc	241	15	CQ	CQ	NNP
cord-026340-2nf97zvc	241	16	interferes	interfere	VBZ
cord-026340-2nf97zvc	241	17	with	with	IN
cord-026340-2nf97zvc	241	18	TLR9	TLR9	NNP
cord-026340-2nf97zvc	241	19	and	and	CC
cord-026340-2nf97zvc	241	20	TLR7	TLR7	NNP
cord-026340-2nf97zvc	241	21	processing	processing	NN
cord-026340-2nf97zvc	241	22	,	,	,
cord-026340-2nf97zvc	241	23	hence	hence	RB
cord-026340-2nf97zvc	241	24	pathogen	pathogen	NN
cord-026340-2nf97zvc	241	25	recognition	recognition	NN
cord-026340-2nf97zvc	241	26	via	via	IN
cord-026340-2nf97zvc	241	27	Toll	Toll	NNP
cord-026340-2nf97zvc	241	28	-	-	HYPH
cord-026340-2nf97zvc	241	29	like	like	JJ
cord-026340-2nf97zvc	241	30	receptor	receptor	NN
cord-026340-2nf97zvc	241	31	(	(	-LRB-
cord-026340-2nf97zvc	241	32	TLR	TLR	NNP
cord-026340-2nf97zvc	241	33	)	)	-RRB-
cord-026340-2nf97zvc	241	34	and	and	CC
cord-026340-2nf97zvc	241	35	thereby	thereby	RB
cord-026340-2nf97zvc	241	36	viral	viral	JJ
cord-026340-2nf97zvc	241	37	infection	infection	NN
cord-026340-2nf97zvc	241	38	(	(	-LRB-
cord-026340-2nf97zvc	241	39	Devaux	Devaux	NNP
cord-026340-2nf97zvc	241	40	et	et	NNP
cord-026340-2nf97zvc	241	41	al	al	NNP
cord-026340-2nf97zvc	241	42	.	.	NNP
cord-026340-2nf97zvc	241	43	2020	2020	CD
cord-026340-2nf97zvc	241	44	)	)	-RRB-
cord-026340-2nf97zvc	242	1	The	the	DT
cord-026340-2nf97zvc	242	2	mechanism	mechanism	NN
cord-026340-2nf97zvc	242	3	of	of	IN
cord-026340-2nf97zvc	242	4	action	action	NN
cord-026340-2nf97zvc	242	5	as	as	IN
cord-026340-2nf97zvc	242	6	detailed	detail	VBN
cord-026340-2nf97zvc	242	7	above	above	RB
cord-026340-2nf97zvc	242	8	for	for	IN
cord-026340-2nf97zvc	242	9	CQ	CQ	NNP
cord-026340-2nf97zvc	242	10	or	or	CC
cord-026340-2nf97zvc	242	11	HCQ	HCQ	NNP
cord-026340-2nf97zvc	242	12	is	be	VBZ
cord-026340-2nf97zvc	242	13	from	from	IN
cord-026340-2nf97zvc	242	14	literature	literature	NN
cord-026340-2nf97zvc	242	15	but	but	CC
cord-026340-2nf97zvc	242	16	this	this	DT
cord-026340-2nf97zvc	242	17	warrants	warrant	VBZ
cord-026340-2nf97zvc	242	18	further	further	JJ
cord-026340-2nf97zvc	242	19	investigations	investigation	NNS
cord-026340-2nf97zvc	242	20	.	.	.
cord-026340-2nf97zvc	243	1	Now	now	RB
cord-026340-2nf97zvc	243	2	,	,	,
cord-026340-2nf97zvc	243	3	the	the	DT
cord-026340-2nf97zvc	243	4	above	above	RB
cord-026340-2nf97zvc	243	5	-	-	HYPH
cord-026340-2nf97zvc	243	6	described	describe	VBN
cord-026340-2nf97zvc	243	7	abilities	ability	NNS
cord-026340-2nf97zvc	243	8	of	of	IN
cord-026340-2nf97zvc	243	9	CQ	CQ	NNP
cord-026340-2nf97zvc	243	10	or	or	CC
cord-026340-2nf97zvc	243	11	HCQ	HCQ	NNP
cord-026340-2nf97zvc	243	12	to	to	TO
cord-026340-2nf97zvc	243	13	function	function	VB
cord-026340-2nf97zvc	243	14	as	as	IN
cord-026340-2nf97zvc	243	15	anti	anti	JJ
cord-026340-2nf97zvc	243	16	-	-	JJ
cord-026340-2nf97zvc	243	17	viral	viral	JJ
cord-026340-2nf97zvc	243	18	and	and	CC
cord-026340-2nf97zvc	243	19	immunomodulatory	immunomodulatory	JJ
cord-026340-2nf97zvc	243	20	agent	agent	NN
cord-026340-2nf97zvc	243	21	highlight	highlight	VB
cord-026340-2nf97zvc	243	22	the	the	DT
cord-026340-2nf97zvc	243	23	rationale	rationale	NN
cord-026340-2nf97zvc	243	24	for	for	IN
cord-026340-2nf97zvc	243	25	usage	usage	NN
cord-026340-2nf97zvc	243	26	of	of	IN
cord-026340-2nf97zvc	243	27	CQ	CQ	NNP
cord-026340-2nf97zvc	243	28	or	or	CC
cord-026340-2nf97zvc	243	29	its	-PRON-	PRP$
cord-026340-2nf97zvc	243	30	derivate	derivate	NN
cord-026340-2nf97zvc	243	31	as	as	IN
cord-026340-2nf97zvc	243	32	both	both	CC
cord-026340-2nf97zvc	243	33	prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	243	34	and	and	CC
cord-026340-2nf97zvc	243	35	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	243	36	agents	agent	NNS
cord-026340-2nf97zvc	243	37	in	in	IN
cord-026340-2nf97zvc	243	38	clinically	clinically	RB
cord-026340-2nf97zvc	243	39	admissible	admissible	JJ
cord-026340-2nf97zvc	243	40	concentrations	concentration	NNS
cord-026340-2nf97zvc	243	41	(	(	-LRB-
cord-026340-2nf97zvc	243	42	Shah	Shah	NNP
cord-026340-2nf97zvc	243	43	et	et	NNP
cord-026340-2nf97zvc	243	44	al	al	NNP
cord-026340-2nf97zvc	243	45	.	.	NNP
cord-026340-2nf97zvc	243	46	2020	2020	CD
cord-026340-2nf97zvc	243	47	)	)	-RRB-
cord-026340-2nf97zvc	243	48	.	.	.
cord-026340-2nf97zvc	244	1	A	a	DT
cord-026340-2nf97zvc	244	2	small	small	JJ
cord-026340-2nf97zvc	244	3	randomized	randomized	JJ
cord-026340-2nf97zvc	244	4	clinical	clinical	JJ
cord-026340-2nf97zvc	244	5	trial	trial	NN
cord-026340-2nf97zvc	244	6	conducted	conduct	VBN
cord-026340-2nf97zvc	244	7	in	in	IN
cord-026340-2nf97zvc	244	8	China	China	NNP
cord-026340-2nf97zvc	244	9	with	with	IN
cord-026340-2nf97zvc	244	10	100	100	CD
cord-026340-2nf97zvc	244	11	patients	patient	NNS
cord-026340-2nf97zvc	244	12	showed	show	VBD
cord-026340-2nf97zvc	244	13	that	that	IN
cord-026340-2nf97zvc	244	14	CQ	CQ	NNP
cord-026340-2nf97zvc	244	15	had	have	VBD
cord-026340-2nf97zvc	244	16	superior	superior	JJ
cord-026340-2nf97zvc	244	17	effects	effect	NNS
cord-026340-2nf97zvc	244	18	in	in	IN
cord-026340-2nf97zvc	244	19	inhibiting	inhibit	VBG
cord-026340-2nf97zvc	244	20	exacerbation	exacerbation	NN
cord-026340-2nf97zvc	244	21	of	of	IN
cord-026340-2nf97zvc	244	22	pneumonia	pneumonia	NN
cord-026340-2nf97zvc	244	23	,	,	,
cord-026340-2nf97zvc	244	24	improving	improve	VBG
cord-026340-2nf97zvc	244	25	lung	lung	NN
cord-026340-2nf97zvc	244	26	-	-	HYPH
cord-026340-2nf97zvc	244	27	imaging	image	VBG
cord-026340-2nf97zvc	244	28	findings	finding	NNS
cord-026340-2nf97zvc	244	29	,	,	,
cord-026340-2nf97zvc	244	30	promoting	promote	VBG
cord-026340-2nf97zvc	244	31	a	a	DT
cord-026340-2nf97zvc	244	32	virus	virus	NN
cord-026340-2nf97zvc	244	33	-	-	HYPH
cord-026340-2nf97zvc	244	34	negative	negative	JJ
cord-026340-2nf97zvc	244	35	conversion	conversion	NN
cord-026340-2nf97zvc	244	36	and	and	CC
cord-026340-2nf97zvc	244	37	shortening	shorten	VBG
cord-026340-2nf97zvc	244	38	the	the	DT
cord-026340-2nf97zvc	244	39	disease	disease	NN
cord-026340-2nf97zvc	244	40	course	course	NN
cord-026340-2nf97zvc	244	41	when	when	WRB
cord-026340-2nf97zvc	244	42	compared	compare	VBN
cord-026340-2nf97zvc	244	43	to	to	IN
cord-026340-2nf97zvc	244	44	a	a	DT
cord-026340-2nf97zvc	244	45	control	control	NN
cord-026340-2nf97zvc	244	46	drug	drug	NN
cord-026340-2nf97zvc	244	47	(	(	-LRB-
cord-026340-2nf97zvc	244	48	Jie	Jie	NNP
cord-026340-2nf97zvc	244	49	et	et	NNP
cord-026340-2nf97zvc	244	50	al	al	NNP
cord-026340-2nf97zvc	244	51	.	.	NNP
cord-026340-2nf97zvc	244	52	2020	2020	CD
cord-026340-2nf97zvc	244	53	;	;	:
cord-026340-2nf97zvc	244	54	Gao	Gao	NNP
cord-026340-2nf97zvc	244	55	et	et	NNP
cord-026340-2nf97zvc	244	56	al	al	NNP
cord-026340-2nf97zvc	244	57	.	.	NNP
cord-026340-2nf97zvc	244	58	2020	2020	CD
cord-026340-2nf97zvc	244	59	)	)	-RRB-
cord-026340-2nf97zvc	245	1	Another	another	DT
cord-026340-2nf97zvc	245	2	clinical	clinical	JJ
cord-026340-2nf97zvc	245	3	trial	trial	NN
cord-026340-2nf97zvc	245	4	in	in	IN
cord-026340-2nf97zvc	245	5	Marseille	Marseille	NNP
cord-026340-2nf97zvc	246	1	,	,	,
cord-026340-2nf97zvc	246	2	France	France	NNP
cord-026340-2nf97zvc	246	3	reported	report	VBD
cord-026340-2nf97zvc	246	4	by	by	IN
cord-026340-2nf97zvc	246	5	Gautret	Gautret	NNP
cord-026340-2nf97zvc	246	6	et	et	NNP
cord-026340-2nf97zvc	246	7	al	al	NNP
cord-026340-2nf97zvc	246	8	.	.	.
cord-026340-2nf97zvc	247	1	(	(	-LRB-
cord-026340-2nf97zvc	247	2	2020	2020	CD
cord-026340-2nf97zvc	247	3	)	)	-RRB-
cord-026340-2nf97zvc	247	4	demonstrated	demonstrate	VBD
cord-026340-2nf97zvc	247	5	that	that	IN
cord-026340-2nf97zvc	247	6	HCQ	HCQ	NNP
cord-026340-2nf97zvc	247	7	has	have	VBZ
cord-026340-2nf97zvc	247	8	efficacy	efficacy	NN
cord-026340-2nf97zvc	247	9	in	in	IN
cord-026340-2nf97zvc	247	10	increasing	increase	VBG
cord-026340-2nf97zvc	247	11	viral	viral	JJ
cord-026340-2nf97zvc	247	12	clearance	clearance	NN
cord-026340-2nf97zvc	247	13	.	.	.
cord-026340-2nf97zvc	248	1	In	in	IN
cord-026340-2nf97zvc	248	2	that	that	DT
cord-026340-2nf97zvc	248	3	non	non	JJ
cord-026340-2nf97zvc	248	4	-	-	JJ
cord-026340-2nf97zvc	248	5	randomized	randomized	JJ
cord-026340-2nf97zvc	248	6	trial	trial	NN
cord-026340-2nf97zvc	248	7	(	(	-LRB-
cord-026340-2nf97zvc	248	8	n	n	NN
cord-026340-2nf97zvc	248	9	=	=	SYM
cord-026340-2nf97zvc	248	10	36	36	CD
cord-026340-2nf97zvc	248	11	)	)	-RRB-
cord-026340-2nf97zvc	248	12	conducted	conduct	VBN
cord-026340-2nf97zvc	248	13	,	,	,
cord-026340-2nf97zvc	248	14	HCQ	HCQ	NNP
cord-026340-2nf97zvc	248	15	alone	alone	RB
cord-026340-2nf97zvc	248	16	and	and	CC
cord-026340-2nf97zvc	248	17	in	in	IN
cord-026340-2nf97zvc	248	18	combination	combination	NN
cord-026340-2nf97zvc	248	19	with	with	IN
cord-026340-2nf97zvc	248	20	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	248	21	antibiotic	antibiotic	NN
cord-026340-2nf97zvc	248	22	effectively	effectively	RB
cord-026340-2nf97zvc	248	23	cleared	clear	VBD
cord-026340-2nf97zvc	248	24	viral	viral	JJ
cord-026340-2nf97zvc	248	25	nasopharyngeal	nasopharyngeal	JJ
cord-026340-2nf97zvc	248	26	carriage	carriage	NN
cord-026340-2nf97zvc	248	27	as	as	IN
cord-026340-2nf97zvc	248	28	evidenced	evidence	VBN
cord-026340-2nf97zvc	248	29	by	by	IN
cord-026340-2nf97zvc	248	30	the	the	DT
cord-026340-2nf97zvc	248	31	gold	gold	NN
cord-026340-2nf97zvc	248	32	standard	standard	NN
cord-026340-2nf97zvc	248	33	PCR	PCR	NNP
cord-026340-2nf97zvc	248	34	(	(	-LRB-
cord-026340-2nf97zvc	248	35	polymerase	polymerase	NN
cord-026340-2nf97zvc	248	36	chain	chain	NN
cord-026340-2nf97zvc	248	37	reaction	reaction	NN
cord-026340-2nf97zvc	248	38	)	)	-RRB-
cord-026340-2nf97zvc	248	39	test	test	NN
cord-026340-2nf97zvc	248	40	(	(	-LRB-
cord-026340-2nf97zvc	248	41	versus	versus	IN
cord-026340-2nf97zvc	248	42	control	control	NN
cord-026340-2nf97zvc	248	43	)	)	-RRB-
cord-026340-2nf97zvc	248	44	.	.	.
cord-026340-2nf97zvc	249	1	The	the	DT
cord-026340-2nf97zvc	249	2	virus	virus	NN
cord-026340-2nf97zvc	249	3	clearance	clearance	NN
cord-026340-2nf97zvc	249	4	at	at	IN
cord-026340-2nf97zvc	249	5	day	day	NN
cord-026340-2nf97zvc	249	6	6	6	CD
cord-026340-2nf97zvc	249	7	post	post	JJ
cord-026340-2nf97zvc	249	8	-	-	JJ
cord-026340-2nf97zvc	249	9	inclusion	inclusion	JJ
cord-026340-2nf97zvc	249	10	HCQ	hcq	NN
cord-026340-2nf97zvc	249	11	vs.	vs.	IN
cord-026340-2nf97zvc	249	12	control	control	NN
cord-026340-2nf97zvc	249	13	was	be	VBD
cord-026340-2nf97zvc	249	14	70.0	70.0	CD
cord-026340-2nf97zvc	249	15	%	%	NN
cord-026340-2nf97zvc	249	16	versus	versus	IN
cord-026340-2nf97zvc	249	17	12.5	12.5	CD
cord-026340-2nf97zvc	249	18	%	%	NN
cord-026340-2nf97zvc	249	19	,	,	,
cord-026340-2nf97zvc	249	20	respectively	respectively	RB
cord-026340-2nf97zvc	249	21	(	(	-LRB-
cord-026340-2nf97zvc	249	22	p	p	NN
cord-026340-2nf97zvc	249	23	=	=	SYM
cord-026340-2nf97zvc	249	24	0.001	0.001	CD
cord-026340-2nf97zvc	249	25	)	)	-RRB-
cord-026340-2nf97zvc	249	26	.	.	.
cord-026340-2nf97zvc	250	1	A	a	DT
cord-026340-2nf97zvc	250	2	higher	high	JJR
cord-026340-2nf97zvc	250	3	virus	virus	NN
cord-026340-2nf97zvc	250	4	clearance	clearance	NN
cord-026340-2nf97zvc	250	5	effect	effect	NN
cord-026340-2nf97zvc	250	6	was	be	VBD
cord-026340-2nf97zvc	250	7	seen	see	VBN
cord-026340-2nf97zvc	250	8	with	with	IN
cord-026340-2nf97zvc	250	9	a	a	DT
cord-026340-2nf97zvc	250	10	combinational	combinational	JJ
cord-026340-2nf97zvc	250	11	therapy	therapy	NN
cord-026340-2nf97zvc	250	12	of	of	IN
cord-026340-2nf97zvc	250	13	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	250	14	and	and	CC
cord-026340-2nf97zvc	250	15	CQ	CQ	NNP
cord-026340-2nf97zvc	250	16	.	.	.
cord-026340-2nf97zvc	251	1	This	this	DT
cord-026340-2nf97zvc	251	2	combinational	combinational	JJ
cord-026340-2nf97zvc	251	3	therapy	therapy	NN
cord-026340-2nf97zvc	251	4	was	be	VBD
cord-026340-2nf97zvc	251	5	effective	effective	JJ
cord-026340-2nf97zvc	251	6	because	because	IN
cord-026340-2nf97zvc	251	7	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	251	8	is	be	VBZ
cord-026340-2nf97zvc	251	9	an	an	DT
cord-026340-2nf97zvc	251	10	anti	anti	JJ
cord-026340-2nf97zvc	251	11	-	-	JJ
cord-026340-2nf97zvc	251	12	viral	viral	JJ
cord-026340-2nf97zvc	251	13	agent	agent	NN
cord-026340-2nf97zvc	251	14	that	that	WDT
cord-026340-2nf97zvc	251	15	has	have	VBZ
cord-026340-2nf97zvc	251	16	shown	show	VBN
cord-026340-2nf97zvc	251	17	efficacy	efficacy	NN
cord-026340-2nf97zvc	251	18	against	against	IN
cord-026340-2nf97zvc	251	19	Zika	Zika	NNP
cord-026340-2nf97zvc	251	20	and	and	CC
cord-026340-2nf97zvc	251	21	Ebola	Ebola	NNP
cord-026340-2nf97zvc	251	22	viruses	virus	NNS
cord-026340-2nf97zvc	252	1	(	(	-LRB-
cord-026340-2nf97zvc	252	2	Gautret	Gautret	NNP
cord-026340-2nf97zvc	252	3	et	et	NNP
cord-026340-2nf97zvc	252	4	al	al	NNP
cord-026340-2nf97zvc	252	5	.	.	NNP
cord-026340-2nf97zvc	252	6	2020	2020	CD
cord-026340-2nf97zvc	252	7	)	)	-RRB-
cord-026340-2nf97zvc	252	8	.	.	.
cord-026340-2nf97zvc	253	1	However	however	RB
cord-026340-2nf97zvc	253	2	,	,	,
cord-026340-2nf97zvc	253	3	all	all	DT
cord-026340-2nf97zvc	253	4	clinical	clinical	JJ
cord-026340-2nf97zvc	253	5	results	result	NNS
cord-026340-2nf97zvc	253	6	did	do	VBD
cord-026340-2nf97zvc	253	7	not	not	RB
cord-026340-2nf97zvc	253	8	show	show	VB
cord-026340-2nf97zvc	253	9	the	the	DT
cord-026340-2nf97zvc	253	10	same	same	JJ
cord-026340-2nf97zvc	253	11	picture	picture	NN
cord-026340-2nf97zvc	253	12	.	.	.
cord-026340-2nf97zvc	254	1	In	in	IN
cord-026340-2nf97zvc	254	2	a	a	DT
cord-026340-2nf97zvc	254	3	randomized	randomized	JJ
cord-026340-2nf97zvc	254	4	study	study	NN
cord-026340-2nf97zvc	254	5	from	from	IN
cord-026340-2nf97zvc	254	6	China	China	NNP
cord-026340-2nf97zvc	254	7	,	,	,
cord-026340-2nf97zvc	254	8	patients	patient	NNS
cord-026340-2nf97zvc	254	9	with	with	IN
cord-026340-2nf97zvc	254	10	mild	mild	JJ
cord-026340-2nf97zvc	254	11	to	to	IN
cord-026340-2nf97zvc	254	12	moderate	moderate	JJ
cord-026340-2nf97zvc	254	13	cases	case	NNS
cord-026340-2nf97zvc	254	14	of	of	IN
cord-026340-2nf97zvc	254	15	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	254	16	did	do	VBD
cord-026340-2nf97zvc	254	17	not	not	RB
cord-026340-2nf97zvc	254	18	show	show	VB
cord-026340-2nf97zvc	254	19	recovery	recovery	NN
cord-026340-2nf97zvc	254	20	rates	rate	NNS
cord-026340-2nf97zvc	254	21	when	when	WRB
cord-026340-2nf97zvc	254	22	treated	treat	VBN
cord-026340-2nf97zvc	254	23	with	with	IN
cord-026340-2nf97zvc	254	24	HCQ	HCQ	NNP
cord-026340-2nf97zvc	254	25	)	)	-RRB-
cord-026340-2nf97zvc	254	26	.	.	.
cord-026340-2nf97zvc	255	1	Likewise	likewise	RB
cord-026340-2nf97zvc	255	2	,	,	,
cord-026340-2nf97zvc	255	3	another	another	DT
cord-026340-2nf97zvc	255	4	study	study	NN
cord-026340-2nf97zvc	255	5	conducted	conduct	VBN
cord-026340-2nf97zvc	255	6	in	in	IN
cord-026340-2nf97zvc	255	7	France	France	NNP
cord-026340-2nf97zvc	255	8	with	with	IN
cord-026340-2nf97zvc	255	9	11	11	CD
cord-026340-2nf97zvc	255	10	hospitalized	hospitalize	VBN
cord-026340-2nf97zvc	255	11	cases	case	NNS
cord-026340-2nf97zvc	255	12	also	also	RB
cord-026340-2nf97zvc	255	13	failed	fail	VBD
cord-026340-2nf97zvc	255	14	to	to	TO
cord-026340-2nf97zvc	255	15	confirm	confirm	VB
cord-026340-2nf97zvc	255	16	anti	anti	JJ
cord-026340-2nf97zvc	255	17	-	-	JJ
cord-026340-2nf97zvc	255	18	viral	viral	JJ
cord-026340-2nf97zvc	255	19	activity	activity	NN
cord-026340-2nf97zvc	255	20	of	of	IN
cord-026340-2nf97zvc	255	21	HCQ	HCQ	NNP
cord-026340-2nf97zvc	255	22	when	when	WRB
cord-026340-2nf97zvc	255	23	administered	administer	VBN
cord-026340-2nf97zvc	255	24	with	with	IN
cord-026340-2nf97zvc	255	25	an	an	DT
cord-026340-2nf97zvc	255	26	azithromycin	azithromycin	NN
cord-026340-2nf97zvc	255	27	(	(	-LRB-
cord-026340-2nf97zvc	255	28	Yazdany	Yazdany	NNP
cord-026340-2nf97zvc	255	29	and	and	CC
cord-026340-2nf97zvc	255	30	Kim	Kim	NNP
cord-026340-2nf97zvc	255	31	2020	2020	CD
cord-026340-2nf97zvc	255	32	)	)	-RRB-
cord-026340-2nf97zvc	255	33	.	.	.
cord-026340-2nf97zvc	256	1	A	a	DT
cord-026340-2nf97zvc	256	2	reason	reason	NN
cord-026340-2nf97zvc	256	3	for	for	IN
cord-026340-2nf97zvc	256	4	the	the	DT
cord-026340-2nf97zvc	256	5	discrepancy	discrepancy	NN
cord-026340-2nf97zvc	256	6	in	in	IN
cord-026340-2nf97zvc	256	7	effect	effect	NN
cord-026340-2nf97zvc	256	8	as	as	IN
cord-026340-2nf97zvc	256	9	noted	note	VBN
cord-026340-2nf97zvc	256	10	among	among	IN
cord-026340-2nf97zvc	256	11	these	these	DT
cord-026340-2nf97zvc	256	12	clinical	clinical	JJ
cord-026340-2nf97zvc	256	13	trials	trial	NNS
cord-026340-2nf97zvc	256	14	could	could	MD
cord-026340-2nf97zvc	256	15	be	be	VB
cord-026340-2nf97zvc	256	16	the	the	DT
cord-026340-2nf97zvc	256	17	dosage	dosage	NN
cord-026340-2nf97zvc	256	18	of	of	IN
cord-026340-2nf97zvc	256	19	CQ	CQ	NNP
cord-026340-2nf97zvc	256	20	or	or	CC
cord-026340-2nf97zvc	256	21	HCQ	HCQ	NNP
cord-026340-2nf97zvc	256	22	selected	select	VBN
cord-026340-2nf97zvc	256	23	;	;	:
cord-026340-2nf97zvc	256	24	a	a	DT
cord-026340-2nf97zvc	256	25	higher	high	JJR
cord-026340-2nf97zvc	256	26	dose	dose	NN
cord-026340-2nf97zvc	256	27	of	of	IN
cord-026340-2nf97zvc	256	28	CQ	CQ	NNP
cord-026340-2nf97zvc	256	29	or	or	CC
cord-026340-2nf97zvc	256	30	HCQ	HCQ	NNP
cord-026340-2nf97zvc	256	31	may	may	MD
cord-026340-2nf97zvc	256	32	be	be	VB
cord-026340-2nf97zvc	256	33	imparting	impart	VBG
cord-026340-2nf97zvc	256	34	untoward	untoward	JJ
cord-026340-2nf97zvc	256	35	implications	implication	NNS
cord-026340-2nf97zvc	256	36	,	,	,
cord-026340-2nf97zvc	256	37	especially	especially	RB
cord-026340-2nf97zvc	256	38	if	if	IN
cord-026340-2nf97zvc	256	39	not	not	RB
cord-026340-2nf97zvc	256	40	monitored	monitor	VBN
cord-026340-2nf97zvc	256	41	.	.	.
cord-026340-2nf97zvc	257	1	The	the	DT
cord-026340-2nf97zvc	257	2	current	current	JJ
cord-026340-2nf97zvc	257	3	doses	dose	NNS
cord-026340-2nf97zvc	257	4	tested	test	VBN
cord-026340-2nf97zvc	257	5	may	may	MD
cord-026340-2nf97zvc	257	6	be	be	VB
cord-026340-2nf97zvc	257	7	with	with	IN
cord-026340-2nf97zvc	257	8	respect	respect	NN
cord-026340-2nf97zvc	257	9	to	to	IN
cord-026340-2nf97zvc	257	10	the	the	DT
cord-026340-2nf97zvc	257	11	antimalarial	antimalarial	JJ
cord-026340-2nf97zvc	257	12	effects	effect	NNS
cord-026340-2nf97zvc	257	13	of	of	IN
cord-026340-2nf97zvc	257	14	CQ	CQ	NNP
cord-026340-2nf97zvc	257	15	and	and	CC
cord-026340-2nf97zvc	257	16	HCQ	HCQ	NNP
cord-026340-2nf97zvc	257	17	when	when	WRB
cord-026340-2nf97zvc	257	18	the	the	DT
cord-026340-2nf97zvc	257	19	body	body	NN
cord-026340-2nf97zvc	257	20	encounters	encounter	VBZ
cord-026340-2nf97zvc	257	21	a	a	DT
cord-026340-2nf97zvc	257	22	deadly	deadly	JJ
cord-026340-2nf97zvc	257	23	pathogen	pathogen	NN
cord-026340-2nf97zvc	257	24	of	of	IN
cord-026340-2nf97zvc	257	25	plasmodium	plasmodium	NN
cord-026340-2nf97zvc	257	26	genus	genus	NN
cord-026340-2nf97zvc	257	27	or	or	CC
cord-026340-2nf97zvc	257	28	even	even	RB
cord-026340-2nf97zvc	257	29	with	with	IN
cord-026340-2nf97zvc	257	30	respect	respect	NN
cord-026340-2nf97zvc	257	31	to	to	IN
cord-026340-2nf97zvc	257	32	the	the	DT
cord-026340-2nf97zvc	257	33	other	other	JJ
cord-026340-2nf97zvc	257	34	viral	viral	JJ
cord-026340-2nf97zvc	257	35	infections	infection	NNS
cord-026340-2nf97zvc	257	36	that	that	WDT
cord-026340-2nf97zvc	257	37	it	-PRON-	PRP
cord-026340-2nf97zvc	257	38	was	be	VBD
cord-026340-2nf97zvc	257	39	tested	test	VBN
cord-026340-2nf97zvc	257	40	with	with	IN
cord-026340-2nf97zvc	257	41	.	.	.
cord-026340-2nf97zvc	258	1	Since	since	IN
cord-026340-2nf97zvc	258	2	CQ	CQ	NNP
cord-026340-2nf97zvc	258	3	is	be	VBZ
cord-026340-2nf97zvc	258	4	effective	effective	JJ
cord-026340-2nf97zvc	258	5	at	at	IN
cord-026340-2nf97zvc	258	6	blocking	block	VBG
cord-026340-2nf97zvc	258	7	viral	viral	JJ
cord-026340-2nf97zvc	258	8	entry	entry	NN
cord-026340-2nf97zvc	258	9	,	,	,
cord-026340-2nf97zvc	258	10	it	-PRON-	PRP
cord-026340-2nf97zvc	258	11	would	would	MD
cord-026340-2nf97zvc	258	12	have	have	VB
cord-026340-2nf97zvc	258	13	better	well	JJR
cord-026340-2nf97zvc	258	14	effects	effect	NNS
cord-026340-2nf97zvc	258	15	as	as	IN
cord-026340-2nf97zvc	258	16	a	a	DT
cord-026340-2nf97zvc	258	17	prophylactic	prophylactic	NN
cord-026340-2nf97zvc	258	18	or	or	CC
cord-026340-2nf97zvc	258	19	for	for	IN
cord-026340-2nf97zvc	258	20	patients	patient	NNS
cord-026340-2nf97zvc	258	21	with	with	IN
cord-026340-2nf97zvc	258	22	mild	mild	JJ
cord-026340-2nf97zvc	258	23	symptoms	symptom	NNS
cord-026340-2nf97zvc	258	24	.	.	.
cord-026340-2nf97zvc	259	1	We	-PRON-	PRP
cord-026340-2nf97zvc	259	2	also	also	RB
cord-026340-2nf97zvc	259	3	see	see	VBP
cord-026340-2nf97zvc	259	4	that	that	IN
cord-026340-2nf97zvc	259	5	trials	trial	NNS
cord-026340-2nf97zvc	259	6	were	be	VBD
cord-026340-2nf97zvc	259	7	conducted	conduct	VBN
cord-026340-2nf97zvc	259	8	during	during	IN
cord-026340-2nf97zvc	259	9	the	the	DT
cord-026340-2nf97zvc	259	10	different	different	JJ
cord-026340-2nf97zvc	259	11	stages	stage	NNS
cord-026340-2nf97zvc	259	12	of	of	IN
cord-026340-2nf97zvc	259	13	the	the	DT
cord-026340-2nf97zvc	259	14	pandemic	pandemic	NN
cord-026340-2nf97zvc	259	15	;	;	:
cord-026340-2nf97zvc	259	16	at	at	IN
cord-026340-2nf97zvc	259	17	severe	severe	JJ
cord-026340-2nf97zvc	259	18	stages	stage	NNS
cord-026340-2nf97zvc	259	19	,	,	,
cord-026340-2nf97zvc	259	20	perhaps	perhaps	RB
cord-026340-2nf97zvc	259	21	,	,	,
cord-026340-2nf97zvc	259	22	a	a	DT
cord-026340-2nf97zvc	259	23	different	different	JJ
cord-026340-2nf97zvc	259	24	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	259	25	regimen	regimen	NN
cord-026340-2nf97zvc	259	26	is	be	VBZ
cord-026340-2nf97zvc	259	27	required	require	VBN
cord-026340-2nf97zvc	259	28	.	.	.
cord-026340-2nf97zvc	260	1	Upon	upon	IN
cord-026340-2nf97zvc	260	2	further	further	JJ
cord-026340-2nf97zvc	260	3	mutations	mutation	NNS
cord-026340-2nf97zvc	260	4	with	with	IN
cord-026340-2nf97zvc	260	5	time	time	NN
cord-026340-2nf97zvc	260	6	(	(	-LRB-
cord-026340-2nf97zvc	260	7	that	that	WDT
cord-026340-2nf97zvc	260	8	is	be	VBZ
cord-026340-2nf97zvc	260	9	seen	see	VBN
cord-026340-2nf97zvc	260	10	in	in	IN
cord-026340-2nf97zvc	260	11	the	the	DT
cord-026340-2nf97zvc	260	12	different	different	JJ
cord-026340-2nf97zvc	260	13	stages	stage	NNS
cord-026340-2nf97zvc	260	14	of	of	IN
cord-026340-2nf97zvc	260	15	a	a	DT
cord-026340-2nf97zvc	260	16	pandemic	pandemic	NN
cord-026340-2nf97zvc	260	17	)	)	-RRB-
cord-026340-2nf97zvc	260	18	,	,	,
cord-026340-2nf97zvc	260	19	the	the	DT
cord-026340-2nf97zvc	260	20	adherence	adherence	NN
cord-026340-2nf97zvc	260	21	propensity	propensity	NN
cord-026340-2nf97zvc	260	22	of	of	IN
cord-026340-2nf97zvc	260	23	the	the	DT
cord-026340-2nf97zvc	260	24	virus	virus	NN
cord-026340-2nf97zvc	260	25	towards	towards	IN
cord-026340-2nf97zvc	260	26	host	host	NN
cord-026340-2nf97zvc	260	27	cells	cell	NNS
cord-026340-2nf97zvc	260	28	may	may	MD
cord-026340-2nf97zvc	260	29	change	change	VB
cord-026340-2nf97zvc	260	30	(	(	-LRB-
cord-026340-2nf97zvc	260	31	increased	increase	VBN
cord-026340-2nf97zvc	260	32	)	)	-RRB-
cord-026340-2nf97zvc	260	33	that	that	IN
cord-026340-2nf97zvc	260	34	CQ	CQ	NNP
cord-026340-2nf97zvc	260	35	or	or	CC
cord-026340-2nf97zvc	260	36	HQ	HQ	NNP
cord-026340-2nf97zvc	260	37	alone	alone	RB
cord-026340-2nf97zvc	260	38	may	may	MD
cord-026340-2nf97zvc	260	39	not	not	RB
cord-026340-2nf97zvc	260	40	be	be	VB
cord-026340-2nf97zvc	260	41	not	not	RB
cord-026340-2nf97zvc	260	42	alone	alone	JJ
cord-026340-2nf97zvc	260	43	sufficient	sufficient	JJ
cord-026340-2nf97zvc	260	44	as	as	IN
cord-026340-2nf97zvc	260	45	an	an	DT
cord-026340-2nf97zvc	260	46	antiviral	antiviral	JJ
cord-026340-2nf97zvc	260	47	therapy	therapy	NN
cord-026340-2nf97zvc	260	48	.	.	.
cord-026340-2nf97zvc	261	1	At	at	IN
cord-026340-2nf97zvc	261	2	the	the	DT
cord-026340-2nf97zvc	261	3	same	same	JJ
cord-026340-2nf97zvc	261	4	time	time	NN
cord-026340-2nf97zvc	261	5	,	,	,
cord-026340-2nf97zvc	261	6	a	a	DT
cord-026340-2nf97zvc	261	7	toxicity	toxicity	NN
cord-026340-2nf97zvc	261	8	profile	profile	NN
cord-026340-2nf97zvc	261	9	of	of	IN
cord-026340-2nf97zvc	261	10	CQ	CQ	NNP
cord-026340-2nf97zvc	261	11	or	or	CC
cord-026340-2nf97zvc	261	12	HCQ	HCQ	NNP
cord-026340-2nf97zvc	261	13	in	in	IN
cord-026340-2nf97zvc	261	14	combination	combination	NN
cord-026340-2nf97zvc	261	15	with	with	IN
cord-026340-2nf97zvc	261	16	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	261	17	versus	versus	IN
cord-026340-2nf97zvc	261	18	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	261	19	and	and	CC
cord-026340-2nf97zvc	261	20	CQ	CQ	NNP
cord-026340-2nf97zvc	261	21	or	or	CC
cord-026340-2nf97zvc	261	22	HCQ	HCQ	NNP
cord-026340-2nf97zvc	261	23	should	should	MD
cord-026340-2nf97zvc	261	24	be	be	VB
cord-026340-2nf97zvc	261	25	conducted	conduct	VBN
cord-026340-2nf97zvc	261	26	to	to	TO
cord-026340-2nf97zvc	261	27	rule	rule	VB
cord-026340-2nf97zvc	261	28	out	out	RP
cord-026340-2nf97zvc	261	29	the	the	DT
cord-026340-2nf97zvc	261	30	toxicity	toxicity	NN
cord-026340-2nf97zvc	261	31	arising	arise	VBG
cord-026340-2nf97zvc	261	32	from	from	IN
cord-026340-2nf97zvc	261	33	combinational	combinational	JJ
cord-026340-2nf97zvc	261	34	therapy	therapy	NN
cord-026340-2nf97zvc	261	35	(	(	-LRB-
cord-026340-2nf97zvc	261	36	Gautret	Gautret	NNP
cord-026340-2nf97zvc	261	37	et	et	NNP
cord-026340-2nf97zvc	261	38	al	al	NNP
cord-026340-2nf97zvc	261	39	.	.	NNP
cord-026340-2nf97zvc	261	40	2020	2020	CD
cord-026340-2nf97zvc	261	41	)	)	-RRB-
cord-026340-2nf97zvc	261	42	.	.	.
cord-026340-2nf97zvc	262	1	Additional	additional	JJ
cord-026340-2nf97zvc	262	2	research	research	NN
cord-026340-2nf97zvc	262	3	to	to	TO
cord-026340-2nf97zvc	262	4	carry	carry	VB
cord-026340-2nf97zvc	262	5	out	out	RP
cord-026340-2nf97zvc	262	6	research	research	NN
cord-026340-2nf97zvc	262	7	on	on	IN
cord-026340-2nf97zvc	262	8	CQ	CQ	NNP
cord-026340-2nf97zvc	262	9	and	and	CC
cord-026340-2nf97zvc	262	10	HCQ	HCQ	NNP
cord-026340-2nf97zvc	262	11	is	be	VBZ
cord-026340-2nf97zvc	262	12	emphasized	emphasize	VBN
cord-026340-2nf97zvc	262	13	because	because	IN
cord-026340-2nf97zvc	262	14	unlike	unlike	IN
cord-026340-2nf97zvc	262	15	other	other	JJ
cord-026340-2nf97zvc	262	16	drugs	drug	NNS
cord-026340-2nf97zvc	262	17	,	,	,
cord-026340-2nf97zvc	262	18	apart	apart	RB
cord-026340-2nf97zvc	262	19	from	from	IN
cord-026340-2nf97zvc	262	20	the	the	DT
cord-026340-2nf97zvc	262	21	ability	ability	NN
cord-026340-2nf97zvc	262	22	to	to	TO
cord-026340-2nf97zvc	262	23	block	block	VB
cord-026340-2nf97zvc	262	24	viral	viral	JJ
cord-026340-2nf97zvc	262	25	infection	infection	NN
cord-026340-2nf97zvc	262	26	,	,	,
cord-026340-2nf97zvc	262	27	these	these	DT
cord-026340-2nf97zvc	262	28	drugs	drug	NNS
cord-026340-2nf97zvc	262	29	also	also	RB
cord-026340-2nf97zvc	262	30	have	have	VBP
cord-026340-2nf97zvc	262	31	immunomodulatory	immunomodulatory	JJ
cord-026340-2nf97zvc	262	32	effects	effect	NNS
cord-026340-2nf97zvc	262	33	which	which	WDT
cord-026340-2nf97zvc	262	34	is	be	VBZ
cord-026340-2nf97zvc	262	35	very	very	RB
cord-026340-2nf97zvc	262	36	much	much	RB
cord-026340-2nf97zvc	262	37	useful	useful	JJ
cord-026340-2nf97zvc	262	38	for	for	IN
cord-026340-2nf97zvc	262	39	countering	counter	VBG
cord-026340-2nf97zvc	262	40	the	the	DT
cord-026340-2nf97zvc	262	41	initiation	initiation	NN
cord-026340-2nf97zvc	262	42	of	of	IN
cord-026340-2nf97zvc	262	43	the	the	DT
cord-026340-2nf97zvc	262	44	cytokine	cytokine	NN
cord-026340-2nf97zvc	262	45	storm	storm	NN
cord-026340-2nf97zvc	262	46	seen	see	VBN
cord-026340-2nf97zvc	262	47	in	in	IN
cord-026340-2nf97zvc	262	48	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	262	49	patients	patient	NNS
cord-026340-2nf97zvc	262	50	(	(	-LRB-
cord-026340-2nf97zvc	262	51	Conti	Conti	NNP
cord-026340-2nf97zvc	262	52	et	et	NNP
cord-026340-2nf97zvc	262	53	al	al	NNP
cord-026340-2nf97zvc	262	54	.	.	NNP
cord-026340-2nf97zvc	262	55	2020	2020	CD
cord-026340-2nf97zvc	262	56	)	)	-RRB-
cord-026340-2nf97zvc	262	57	.	.	.
cord-026340-2nf97zvc	263	1	Although	although	IN
cord-026340-2nf97zvc	263	2	this	this	DT
cord-026340-2nf97zvc	263	3	review	review	NN
cord-026340-2nf97zvc	263	4	focuses	focus	VBZ
cord-026340-2nf97zvc	263	5	on	on	IN
cord-026340-2nf97zvc	263	6	the	the	DT
cord-026340-2nf97zvc	263	7	beneficial	beneficial	JJ
cord-026340-2nf97zvc	263	8	effects	effect	NNS
cord-026340-2nf97zvc	263	9	of	of	IN
cord-026340-2nf97zvc	263	10	CQ	CQ	NNP
cord-026340-2nf97zvc	263	11	,	,	,
cord-026340-2nf97zvc	263	12	we	-PRON-	PRP
cord-026340-2nf97zvc	263	13	do	do	VBP
cord-026340-2nf97zvc	263	14	not	not	RB
cord-026340-2nf97zvc	263	15	overlook	overlook	VB
cord-026340-2nf97zvc	263	16	some	some	DT
cord-026340-2nf97zvc	263	17	of	of	IN
cord-026340-2nf97zvc	263	18	the	the	DT
cord-026340-2nf97zvc	263	19	precautions	precaution	NNS
cord-026340-2nf97zvc	263	20	as	as	IN
cord-026340-2nf97zvc	263	21	evidenced	evidence	VBN
cord-026340-2nf97zvc	263	22	from	from	IN
cord-026340-2nf97zvc	263	23	clinical	clinical	JJ
cord-026340-2nf97zvc	263	24	studies	study	NNS
cord-026340-2nf97zvc	263	25	(	(	-LRB-
cord-026340-2nf97zvc	263	26	van	van	NNP
cord-026340-2nf97zvc	263	27	den	den	NNP
cord-026340-2nf97zvc	263	28	Broek	Broek	NNP
cord-026340-2nf97zvc	263	29	et	et	NNP
cord-026340-2nf97zvc	263	30	al	al	NNP
cord-026340-2nf97zvc	263	31	.	.	NNP
cord-026340-2nf97zvc	263	32	2020	2020	CD
cord-026340-2nf97zvc	263	33	)	)	-RRB-
cord-026340-2nf97zvc	263	34	.	.	.
cord-026340-2nf97zvc	264	1	During	during	IN
cord-026340-2nf97zvc	264	2	the	the	DT
cord-026340-2nf97zvc	264	3	course	course	NN
cord-026340-2nf97zvc	264	4	of	of	IN
cord-026340-2nf97zvc	264	5	the	the	DT
cord-026340-2nf97zvc	264	6	prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	264	7	or	or	CC
cord-026340-2nf97zvc	264	8	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	264	9	regimen	regimen	NN
cord-026340-2nf97zvc	264	10	involving	involve	VBG
cord-026340-2nf97zvc	264	11	CQ	CQ	NNP
cord-026340-2nf97zvc	264	12	or	or	CC
cord-026340-2nf97zvc	264	13	HCQ	HCQ	NNP
cord-026340-2nf97zvc	264	14	,	,	,
cord-026340-2nf97zvc	264	15	frequent	frequent	JJ
cord-026340-2nf97zvc	264	16	monitoring	monitoring	NN
cord-026340-2nf97zvc	264	17	of	of	IN
cord-026340-2nf97zvc	264	18	hematological	hematological	JJ
cord-026340-2nf97zvc	264	19	parameters	parameter	NNS
cord-026340-2nf97zvc	264	20	(	(	-LRB-
cord-026340-2nf97zvc	264	21	RBC	RBC	NNP
cord-026340-2nf97zvc	264	22	,	,	,
cord-026340-2nf97zvc	264	23	WBC	WBC	NNP
cord-026340-2nf97zvc	264	24	and	and	CC
cord-026340-2nf97zvc	264	25	platelet	platelet	NN
cord-026340-2nf97zvc	264	26	counts	count	NNS
cord-026340-2nf97zvc	264	27	)	)	-RRB-
cord-026340-2nf97zvc	264	28	,	,	,
cord-026340-2nf97zvc	264	29	measurement	measurement	NN
cord-026340-2nf97zvc	264	30	of	of	IN
cord-026340-2nf97zvc	264	31	serum	serum	NN
cord-026340-2nf97zvc	264	32	electrolytes	electrolyte	NNS
cord-026340-2nf97zvc	264	33	,	,	,
cord-026340-2nf97zvc	264	34	blood	blood	NN
cord-026340-2nf97zvc	264	35	glucose	glucose	NN
cord-026340-2nf97zvc	264	36	(	(	-LRB-
cord-026340-2nf97zvc	264	37	owing	owe	VBG
cord-026340-2nf97zvc	264	38	to	to	IN
cord-026340-2nf97zvc	264	39	the	the	DT
cord-026340-2nf97zvc	264	40	hypoglycemic	hypoglycemic	JJ
cord-026340-2nf97zvc	264	41	potential	potential	NN
cord-026340-2nf97zvc	264	42	of	of	IN
cord-026340-2nf97zvc	264	43	HCQ	HCQ	NNP
cord-026340-2nf97zvc	264	44	)	)	-RRB-
cord-026340-2nf97zvc	264	45	,	,	,
cord-026340-2nf97zvc	264	46	liver	liver	NN
cord-026340-2nf97zvc	264	47	function	function	NN
cord-026340-2nf97zvc	264	48	test	test	NN
cord-026340-2nf97zvc	264	49	,	,	,
cord-026340-2nf97zvc	264	50	kidney	kidney	NN
cord-026340-2nf97zvc	264	51	function	function	NN
cord-026340-2nf97zvc	264	52	test	test	NN
cord-026340-2nf97zvc	264	53	and	and	CC
cord-026340-2nf97zvc	264	54	electrocardiography	electrocardiography	NN
cord-026340-2nf97zvc	264	55	are	be	VBP
cord-026340-2nf97zvc	264	56	warranted	warrant	VBN
cord-026340-2nf97zvc	264	57	at	at	IN
cord-026340-2nf97zvc	264	58	time	time	NN
cord-026340-2nf97zvc	264	59	intervals	interval	NNS
cord-026340-2nf97zvc	264	60	to	to	TO
cord-026340-2nf97zvc	264	61	rule	rule	VB
cord-026340-2nf97zvc	264	62	out	out	RP
cord-026340-2nf97zvc	264	63	any	any	DT
cord-026340-2nf97zvc	264	64	toxicity	toxicity	NN
cord-026340-2nf97zvc	264	65	.	.	.
cord-026340-2nf97zvc	265	1	Combinational	combinational	JJ
cord-026340-2nf97zvc	265	2	therapy	therapy	NN
cord-026340-2nf97zvc	265	3	of	of	IN
cord-026340-2nf97zvc	265	4	CQ	CQ	NNP
cord-026340-2nf97zvc	265	5	with	with	IN
cord-026340-2nf97zvc	265	6	any	any	DT
cord-026340-2nf97zvc	265	7	other	other	JJ
cord-026340-2nf97zvc	265	8	allopathic	allopathic	JJ
cord-026340-2nf97zvc	265	9	drug	drug	NN
cord-026340-2nf97zvc	265	10	be	be	VB
cord-026340-2nf97zvc	265	11	it	-PRON-	PRP
cord-026340-2nf97zvc	265	12	azithromycin	azithromycin	NN
cord-026340-2nf97zvc	265	13	,	,	.
cord-026340-2nf97zvc	266	1	lopinavir/	lopinavir/	CD
cord-026340-2nf97zvc	266	2	ritonavir	ritonavir	NNS
cord-026340-2nf97zvc	266	3	and	and	CC
cord-026340-2nf97zvc	266	4	remdesivir	remdesivir	NNP
cord-026340-2nf97zvc	266	5	is	be	VBZ
cord-026340-2nf97zvc	266	6	warranted	warrant	VBN
cord-026340-2nf97zvc	266	7	only	only	RB
cord-026340-2nf97zvc	266	8	after	after	IN
cord-026340-2nf97zvc	266	9	testing	test	VBG
cord-026340-2nf97zvc	266	10	in	in	IN
cord-026340-2nf97zvc	266	11	in	in	FW
cord-026340-2nf97zvc	266	12	vitro	vitro	FW
cord-026340-2nf97zvc	266	13	model	model	NN
cord-026340-2nf97zvc	266	14	systems	system	NNS
cord-026340-2nf97zvc	266	15	and	and	CC
cord-026340-2nf97zvc	266	16	pre	pre	JJ
cord-026340-2nf97zvc	266	17	-	-	JJ
cord-026340-2nf97zvc	266	18	clinical	clinical	JJ
cord-026340-2nf97zvc	266	19	trials	trial	NNS
cord-026340-2nf97zvc	266	20	.	.	.
cord-026340-2nf97zvc	267	1	Clinical	clinical	JJ
cord-026340-2nf97zvc	267	2	experience	experience	NN
cord-026340-2nf97zvc	267	3	has	have	VBZ
cord-026340-2nf97zvc	267	4	shown	show	VBN
cord-026340-2nf97zvc	267	5	that	that	IN
cord-026340-2nf97zvc	267	6	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	267	7	is	be	VBZ
cord-026340-2nf97zvc	267	8	well	well	RB
cord-026340-2nf97zvc	267	9	absorbed	absorb	VBN
cord-026340-2nf97zvc	267	10	in	in	IN
cord-026340-2nf97zvc	267	11	the	the	DT
cord-026340-2nf97zvc	267	12	body	body	NN
cord-026340-2nf97zvc	267	13	and	and	CC
cord-026340-2nf97zvc	267	14	distributes	distribute	VBZ
cord-026340-2nf97zvc	267	15	widely	widely	RB
cord-026340-2nf97zvc	267	16	in	in	IN
cord-026340-2nf97zvc	267	17	the	the	DT
cord-026340-2nf97zvc	267	18	system	system	NN
cord-026340-2nf97zvc	267	19	.	.	.
cord-026340-2nf97zvc	268	1	It	-PRON-	PRP
cord-026340-2nf97zvc	268	2	has	have	VBZ
cord-026340-2nf97zvc	268	3	an	an	DT
cord-026340-2nf97zvc	268	4	apparent	apparent	JJ
cord-026340-2nf97zvc	268	5	and	and	CC
cord-026340-2nf97zvc	268	6	terminal	terminal	JJ
cord-026340-2nf97zvc	268	7	half	half	JJ
cord-026340-2nf97zvc	268	8	-	-	HYPH
cord-026340-2nf97zvc	268	9	life	life	NN
cord-026340-2nf97zvc	268	10	of	of	IN
cord-026340-2nf97zvc	268	11	1.6	1.6	CD
cord-026340-2nf97zvc	268	12	days	day	NNS
cord-026340-2nf97zvc	268	13	and	and	CC
cord-026340-2nf97zvc	268	14	2	2	CD
cord-026340-2nf97zvc	268	15	weeks	week	NNS
cord-026340-2nf97zvc	268	16	,	,	,
cord-026340-2nf97zvc	268	17	respectively	respectively	RB
cord-026340-2nf97zvc	269	1	(	(	-LRB-
cord-026340-2nf97zvc	269	2	Smit	Smit	NNP
cord-026340-2nf97zvc	269	3	et	et	NNP
cord-026340-2nf97zvc	269	4	al	al	NNP
cord-026340-2nf97zvc	269	5	.	.	NNP
cord-026340-2nf97zvc	269	6	2020	2020	CD
cord-026340-2nf97zvc	269	7	)	)	-RRB-
cord-026340-2nf97zvc	269	8	.	.	.
cord-026340-2nf97zvc	270	1	The	the	DT
cord-026340-2nf97zvc	270	2	drug	drug	NN
cord-026340-2nf97zvc	270	3	is	be	VBZ
cord-026340-2nf97zvc	270	4	metabolized	metabolize	VBN
cord-026340-2nf97zvc	270	5	by	by	IN
cord-026340-2nf97zvc	270	6	cytochrome	cytochrome	NN
cord-026340-2nf97zvc	270	7	P450	p450	JJ
cord-026340-2nf97zvc	270	8	and	and	CC
cord-026340-2nf97zvc	270	9	renal	renal	JJ
cord-026340-2nf97zvc	270	10	clearance	clearance	NN
cord-026340-2nf97zvc	270	11	is	be	VBZ
cord-026340-2nf97zvc	270	12	responsible	responsible	JJ
cord-026340-2nf97zvc	270	13	for	for	IN
cord-026340-2nf97zvc	270	14	one	one	CD
cord-026340-2nf97zvc	270	15	-	-	HYPH
cord-026340-2nf97zvc	270	16	third	third	NN
cord-026340-2nf97zvc	270	17	of	of	IN
cord-026340-2nf97zvc	270	18	total	total	JJ
cord-026340-2nf97zvc	270	19	clearance	clearance	NN
cord-026340-2nf97zvc	270	20	of	of	IN
cord-026340-2nf97zvc	270	21	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	270	22	(	(	-LRB-
cord-026340-2nf97zvc	270	23	Smit	Smit	NNP
cord-026340-2nf97zvc	270	24	et	et	NNP
cord-026340-2nf97zvc	270	25	al	al	NNP
cord-026340-2nf97zvc	270	26	.	.	NNP
cord-026340-2nf97zvc	270	27	2020	2020	CD
cord-026340-2nf97zvc	270	28	)	)	-RRB-
cord-026340-2nf97zvc	270	29	.	.	.
cord-026340-2nf97zvc	271	1	So	so	RB
cord-026340-2nf97zvc	271	2	with	with	IN
cord-026340-2nf97zvc	271	3	lower	low	JJR
cord-026340-2nf97zvc	271	4	dose	dose	NN
cord-026340-2nf97zvc	271	5	,	,	,
cord-026340-2nf97zvc	271	6	it	-PRON-	PRP
cord-026340-2nf97zvc	271	7	is	be	VBZ
cord-026340-2nf97zvc	271	8	probable	probable	JJ
cord-026340-2nf97zvc	271	9	that	that	IN
cord-026340-2nf97zvc	271	10	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	271	11	can	can	MD
cord-026340-2nf97zvc	271	12	be	be	VB
cord-026340-2nf97zvc	271	13	used	use	VBN
cord-026340-2nf97zvc	271	14	safely	safely	RB
cord-026340-2nf97zvc	271	15	for	for	IN
cord-026340-2nf97zvc	271	16	an	an	DT
cord-026340-2nf97zvc	271	17	acute	acute	JJ
cord-026340-2nf97zvc	271	18	virus	virus	NN
cord-026340-2nf97zvc	271	19	infection	infection	NN
cord-026340-2nf97zvc	271	20	.	.	.
cord-026340-2nf97zvc	272	1	But	but	CC
cord-026340-2nf97zvc	272	2	some	some	DT
cord-026340-2nf97zvc	272	3	of	of	IN
cord-026340-2nf97zvc	272	4	the	the	DT
cord-026340-2nf97zvc	272	5	potential	potential	JJ
cord-026340-2nf97zvc	272	6	side	side	NN
cord-026340-2nf97zvc	272	7	effects	effect	NNS
cord-026340-2nf97zvc	272	8	of	of	IN
cord-026340-2nf97zvc	272	9	HCQ	HCQ	NNP
cord-026340-2nf97zvc	272	10	and	and	CC
cord-026340-2nf97zvc	272	11	CQ	CQ	NNP
cord-026340-2nf97zvc	272	12	,	,	,
cord-026340-2nf97zvc	272	13	such	such	JJ
cord-026340-2nf97zvc	272	14	as	as	IN
cord-026340-2nf97zvc	272	15	retinopathy	retinopathy	NN
cord-026340-2nf97zvc	272	16	,	,	,
cord-026340-2nf97zvc	272	17	vomiting	vomiting	NN
cord-026340-2nf97zvc	272	18	,	,	,
cord-026340-2nf97zvc	272	19	diarrhea	diarrhea	NN
cord-026340-2nf97zvc	272	20	and	and	CC
cord-026340-2nf97zvc	272	21	increased	increase	VBN
cord-026340-2nf97zvc	272	22	risk	risk	NN
cord-026340-2nf97zvc	272	23	of	of	IN
cord-026340-2nf97zvc	272	24	arrhythmia	arrhythmia	NN
cord-026340-2nf97zvc	272	25	,	,	,
cord-026340-2nf97zvc	272	26	should	should	MD
cord-026340-2nf97zvc	272	27	be	be	VB
cord-026340-2nf97zvc	272	28	also	also	RB
cord-026340-2nf97zvc	272	29	taken	take	VBN
cord-026340-2nf97zvc	272	30	into	into	IN
cord-026340-2nf97zvc	272	31	account	account	NN
cord-026340-2nf97zvc	273	1	(	(	-LRB-
cord-026340-2nf97zvc	273	2	Conti	Conti	NNP
cord-026340-2nf97zvc	273	3	et	et	NNP
cord-026340-2nf97zvc	273	4	al	al	NNP
cord-026340-2nf97zvc	273	5	.	.	NNP
cord-026340-2nf97zvc	273	6	2020	2020	CD
cord-026340-2nf97zvc	273	7	)	)	-RRB-
cord-026340-2nf97zvc	274	1	and	and	CC
cord-026340-2nf97zvc	274	2	we	-PRON-	PRP
cord-026340-2nf97zvc	274	3	presume	presume	VBP
cord-026340-2nf97zvc	274	4	that	that	IN
cord-026340-2nf97zvc	274	5	these	these	DT
cord-026340-2nf97zvc	274	6	may	may	MD
cord-026340-2nf97zvc	274	7	be	be	VB
cord-026340-2nf97zvc	274	8	countered	counter	VBN
cord-026340-2nf97zvc	274	9	by	by	IN
cord-026340-2nf97zvc	274	10	a	a	DT
cord-026340-2nf97zvc	274	11	combinational	combinational	JJ
cord-026340-2nf97zvc	274	12	therapy	therapy	NN
cord-026340-2nf97zvc	274	13	wherein	wherein	WRB
cord-026340-2nf97zvc	274	14	the	the	DT
cord-026340-2nf97zvc	274	15	beneficial	beneficial	JJ
cord-026340-2nf97zvc	274	16	effect	effect	NN
cord-026340-2nf97zvc	274	17	of	of	IN
cord-026340-2nf97zvc	274	18	CQ	CQ	NNP
cord-026340-2nf97zvc	274	19	may	may	MD
cord-026340-2nf97zvc	274	20	be	be	VB
cord-026340-2nf97zvc	274	21	10	10	CD
cord-026340-2nf97zvc	274	22	HCQ	HCQ	NNP
cord-026340-2nf97zvc	274	23	associated	associate	VBN
cord-026340-2nf97zvc	274	24	with	with	IN
cord-026340-2nf97zvc	274	25	azithromycin	azithromycin	NN
cord-026340-2nf97zvc	274	26	(	(	-LRB-
cord-026340-2nf97zvc	274	27	500	500	CD
cord-026340-2nf97zvc	274	28	mg	mg	NN
cord-026340-2nf97zvc	274	29	at	at	IN
cord-026340-2nf97zvc	274	30	day	day	NN
cord-026340-2nf97zvc	274	31	1	1	CD
cord-026340-2nf97zvc	274	32	followed	follow	VBD
cord-026340-2nf97zvc	274	33	by	by	IN
cord-026340-2nf97zvc	274	34	250	250	CD
cord-026340-2nf97zvc	274	35	mg	mg	NNS
cord-026340-2nf97zvc	274	36	once	once	RB
cord-026340-2nf97zvc	274	37	daily	daily	RB
cord-026340-2nf97zvc	274	38	the	the	DT
cord-026340-2nf97zvc	274	39	next	next	JJ
cord-026340-2nf97zvc	274	40	4	4	CD
cord-026340-2nf97zvc	274	41	days	day	NNS
cord-026340-2nf97zvc	274	42	)	)	-RRB-
cord-026340-2nf97zvc	275	1	Therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	275	2	HCQ	HCQ	NNP
cord-026340-2nf97zvc	275	3	and	and	CC
cord-026340-2nf97zvc	275	4	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	275	5	as	as	IN
cord-026340-2nf97zvc	275	6	a	a	DT
cord-026340-2nf97zvc	275	7	treatment	treatment	NN
cord-026340-2nf97zvc	275	8	of	of	IN
cord-026340-2nf97zvc	275	9	COVID-19	covid-19	NN
cord-026340-2nf97zvc	275	10	:	:	:
cord-026340-2nf97zvc	275	11	results	result	NNS
cord-026340-2nf97zvc	275	12	of	of	IN
cord-026340-2nf97zvc	275	13	an	an	DT
cord-026340-2nf97zvc	275	14	open	open	JJ
cord-026340-2nf97zvc	275	15	label	label	NN
cord-026340-2nf97zvc	275	16	nonrandomized	nonrandomize	VBN
cord-026340-2nf97zvc	275	17	clinical	clinical	JJ
cord-026340-2nf97zvc	275	18	trial	trial	NN
cord-026340-2nf97zvc	276	1	(	(	-LRB-
cord-026340-2nf97zvc	276	2	Gautret	Gautret	NNP
cord-026340-2nf97zvc	276	3	et	et	NNP
cord-026340-2nf97zvc	276	4	al	al	NNP
cord-026340-2nf97zvc	276	5	.	.	NNP
cord-026340-2nf97zvc	276	6	2020	2020	CD
cord-026340-2nf97zvc	276	7	)	)	-RRB-
cord-026340-2nf97zvc	277	1	11	11	CD
cord-026340-2nf97zvc	277	2	CQ	CQ	NNP
cord-026340-2nf97zvc	277	3	(	(	-LRB-
cord-026340-2nf97zvc	277	4	300	300	CD
cord-026340-2nf97zvc	277	5	mg	mg	NNP
cord-026340-2nf97zvc	277	6	)	)	-RRB-
cord-026340-2nf97zvc	277	7	once	once	RB
cord-026340-2nf97zvc	277	8	weekly	weekly	RB
cord-026340-2nf97zvc	277	9	alone	alone	RB
cord-026340-2nf97zvc	277	10	or	or	CC
cord-026340-2nf97zvc	277	11	in	in	IN
cord-026340-2nf97zvc	277	12	combination	combination	NN
cord-026340-2nf97zvc	277	13	with	with	IN
cord-026340-2nf97zvc	277	14	proguanil	proguanil	NNP
cord-026340-2nf97zvc	277	15	200	200	CD
cord-026340-2nf97zvc	277	16	mg	mg	NNP
cord-026340-2nf97zvc	277	17	daily	daily	JJ
cord-026340-2nf97zvc	277	18	Prophylactic	Prophylactic	NNP
cord-026340-2nf97zvc	277	19	Compliance	Compliance	NNP
cord-026340-2nf97zvc	277	20	and	and	CC
cord-026340-2nf97zvc	277	21	tolerability	tolerability	NN
cord-026340-2nf97zvc	277	22	of	of	IN
cord-026340-2nf97zvc	277	23	mefloquine	mefloquine	NN
cord-026340-2nf97zvc	277	24	and	and	CC
cord-026340-2nf97zvc	277	25	chloroquine	chloroquine	NNP
cord-026340-2nf97zvc	277	26	plus	plus	CC
cord-026340-2nf97zvc	277	27	proguanil	proguanil	NN
cord-026340-2nf97zvc	277	28	for	for	IN
cord-026340-2nf97zvc	277	29	longterm	longterm	JJ
cord-026340-2nf97zvc	277	30	malaria	malaria	NN
cord-026340-2nf97zvc	277	31	chemoprophylaxis	chemoprophylaxis	NNP
cord-026340-2nf97zvc	277	32	in	in	IN
cord-026340-2nf97zvc	277	33	groups	group	NNS
cord-026340-2nf97zvc	277	34	at	at	IN
cord-026340-2nf97zvc	277	35	particular	particular	JJ
cord-026340-2nf97zvc	277	36	risk	risk	NN
cord-026340-2nf97zvc	277	37	(	(	-LRB-
cord-026340-2nf97zvc	277	38	the	the	DT
cord-026340-2nf97zvc	277	39	military	military	NN
cord-026340-2nf97zvc	277	40	)	)	-RRB-
cord-026340-2nf97zvc	278	1	(	(	-LRB-
cord-026340-2nf97zvc	278	2	Peragallo	Peragallo	NNP
cord-026340-2nf97zvc	278	3	et	et	NNP
cord-026340-2nf97zvc	278	4	al	al	NNP
cord-026340-2nf97zvc	278	5	.	.	.
cord-026340-2nf97zvc	278	6	1999	1999	CD
cord-026340-2nf97zvc	278	7	)	)	-RRB-
cord-026340-2nf97zvc	279	1	12	12	CD
cord-026340-2nf97zvc	279	2	CQ	CQ	NNP
cord-026340-2nf97zvc	279	3	(	(	-LRB-
cord-026340-2nf97zvc	279	4	100	100	CD
cord-026340-2nf97zvc	279	5	mg	mg	NNP
cord-026340-2nf97zvc	279	6	)	)	-RRB-
cord-026340-2nf97zvc	279	7	daily	daily	JJ
cord-026340-2nf97zvc	279	8	or	or	CC
cord-026340-2nf97zvc	279	9	HCQ	HCQ	NNP
cord-026340-2nf97zvc	279	10	(	(	-LRB-
cord-026340-2nf97zvc	279	11	300	300	CD
cord-026340-2nf97zvc	279	12	mg	mg	NNP
cord-026340-2nf97zvc	279	13	)	)	-RRB-
cord-026340-2nf97zvc	279	14	weekly	weekly	JJ
cord-026340-2nf97zvc	279	15	Prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	279	16	Protecting	protect	VBG
cord-026340-2nf97zvc	279	17	Chinese	chinese	JJ
cord-026340-2nf97zvc	279	18	healthcare	healthcare	NN
cord-026340-2nf97zvc	279	19	workers	worker	NNS
cord-026340-2nf97zvc	279	20	while	while	IN
cord-026340-2nf97zvc	279	21	combating	combat	VBG
cord-026340-2nf97zvc	279	22	the	the	DT
cord-026340-2nf97zvc	279	23	2019	2019	CD
cord-026340-2nf97zvc	279	24	novel	novel	NN
cord-026340-2nf97zvc	279	25	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	279	26	(	(	-LRB-
cord-026340-2nf97zvc	279	27	Zhou	Zhou	NNP
cord-026340-2nf97zvc	279	28	et	et	NNP
cord-026340-2nf97zvc	279	29	al	al	NNP
cord-026340-2nf97zvc	279	30	.	.	NNP
cord-026340-2nf97zvc	279	31	2020	2020	CD
cord-026340-2nf97zvc	279	32	)	)	-RRB-
cord-026340-2nf97zvc	279	33	13	13	CD
cord-026340-2nf97zvc	279	34	CQ	CQ	NNP
cord-026340-2nf97zvc	279	35	(	(	-LRB-
cord-026340-2nf97zvc	279	36	500	500	CD
cord-026340-2nf97zvc	279	37	mg	mg	NNP
cord-026340-2nf97zvc	279	38	)	)	-RRB-
cord-026340-2nf97zvc	279	39	once	once	IN
cord-026340-2nf97zvc	279	40	weekly	weekly	JJ
cord-026340-2nf97zvc	279	41	Prophylactic	Prophylactic	NNP
cord-026340-2nf97zvc	279	42	Landscape	Landscape	NNP
cord-026340-2nf97zvc	279	43	analysis	analysis	NN
cord-026340-2nf97zvc	279	44	of	of	IN
cord-026340-2nf97zvc	279	45	therapeutics	therapeutic	NNS
cord-026340-2nf97zvc	279	46	as	as	IN
cord-026340-2nf97zvc	279	47	21st	21st	JJ
cord-026340-2nf97zvc	279	48	March	March	NNP
cord-026340-2nf97zvc	279	49	2020	2020	CD
cord-026340-2nf97zvc	280	1	(	(	-LRB-
cord-026340-2nf97zvc	280	2	WHO	who	WP
cord-026340-2nf97zvc	280	3	2020a	2020a	CD
cord-026340-2nf97zvc	280	4	)	)	-RRB-
cord-026340-2nf97zvc	281	1	14	14	CD
cord-026340-2nf97zvc	281	2	CQ	CQ	NNP
cord-026340-2nf97zvc	281	3	(	(	-LRB-
cord-026340-2nf97zvc	281	4	500	500	CD
cord-026340-2nf97zvc	281	5	mg	mg	NN
cord-026340-2nf97zvc	281	6	)	)	-RRB-
cord-026340-2nf97zvc	282	1	twice	twice	RB
cord-026340-2nf97zvc	282	2	daily	daily	RB
cord-026340-2nf97zvc	282	3	for	for	IN
cord-026340-2nf97zvc	282	4	10	10	CD
cord-026340-2nf97zvc	282	5	days	day	NNS
cord-026340-2nf97zvc	283	1	Prophylactic	Prophylactic	NNP
cord-026340-2nf97zvc	283	2	Expert	Expert	NNP
cord-026340-2nf97zvc	283	3	consensus	consensus	NN
cord-026340-2nf97zvc	283	4	on	on	IN
cord-026340-2nf97zvc	283	5	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	283	6	phosphate	phosphate	NN
cord-026340-2nf97zvc	283	7	for	for	IN
cord-026340-2nf97zvc	283	8	the	the	DT
cord-026340-2nf97zvc	283	9	treatment	treatment	NN
cord-026340-2nf97zvc	283	10	of	of	IN
cord-026340-2nf97zvc	283	11	novel	novel	JJ
cord-026340-2nf97zvc	283	12	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	283	13	pneumonia	pneumonia	NN
cord-026340-2nf97zvc	284	1	(	(	-LRB-
cord-026340-2nf97zvc	284	2	Jie	Jie	NNP
cord-026340-2nf97zvc	284	3	et	et	NNP
cord-026340-2nf97zvc	284	4	al	al	NNP
cord-026340-2nf97zvc	284	5	.	.	NNP
cord-026340-2nf97zvc	284	6	2020	2020	CD
cord-026340-2nf97zvc	284	7	)	)	-RRB-
cord-026340-2nf97zvc	285	1	15	15	CD
cord-026340-2nf97zvc	285	2	HCQ	HCQ	NNP
cord-026340-2nf97zvc	285	3	(	(	-LRB-
cord-026340-2nf97zvc	285	4	400	400	CD
cord-026340-2nf97zvc	285	5	mg	mg	NNP
cord-026340-2nf97zvc	285	6	)	)	-RRB-
cord-026340-2nf97zvc	285	7	twice	twice	RB
cord-026340-2nf97zvc	285	8	daily	daily	RB
cord-026340-2nf97zvc	285	9	,	,	,
cord-026340-2nf97zvc	285	10	followed	follow	VBN
cord-026340-2nf97zvc	285	11	by	by	IN
cord-026340-2nf97zvc	285	12	once	once	RB
cord-026340-2nf97zvc	285	13	weekly	weekly	JJ
cord-026340-2nf97zvc	285	14	Prophylactic	Prophylactic	NNP
cord-026340-2nf97zvc	285	15	Indian	Indian	NNP
cord-026340-2nf97zvc	285	16	Council	Council	NNP
cord-026340-2nf97zvc	285	17	of	of	IN
cord-026340-2nf97zvc	285	18	Medical	Medical	NNP
cord-026340-2nf97zvc	285	19	Research	Research	NNP
cord-026340-2nf97zvc	285	20	.	.	.
cord-026340-2nf97zvc	286	1	Advisory	advisory	NN
cord-026340-2nf97zvc	286	2	on	on	IN
cord-026340-2nf97zvc	286	3	the	the	DT
cord-026340-2nf97zvc	286	4	use	use	NN
cord-026340-2nf97zvc	286	5	of	of	IN
cord-026340-2nf97zvc	286	6	hydroxy	hydroxy	NN
cord-026340-2nf97zvc	286	7	-	-	HYPH
cord-026340-2nf97zvc	286	8	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	286	9	as	as	IN
cord-026340-2nf97zvc	286	10	prophylaxis	prophylaxis	NN
cord-026340-2nf97zvc	286	11	for	for	IN
cord-026340-2nf97zvc	286	12	SARS	SARS	NNP
cord-026340-2nf97zvc	286	13	-	-	HYPH
cord-026340-2nf97zvc	286	14	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	286	15	infection	infection	NN
cord-026340-2nf97zvc	286	16	(	(	-LRB-
cord-026340-2nf97zvc	286	17	ICMR	ICMR	NNP
cord-026340-2nf97zvc	286	18	2020	2020	CD
cord-026340-2nf97zvc	286	19	,	,	,
cord-026340-2nf97zvc	286	20	Kalantri	Kalantri	NNP
cord-026340-2nf97zvc	286	21	et	et	FW
cord-026340-2nf97zvc	286	22	al	al	NNP
cord-026340-2nf97zvc	286	23	.	.	.
cord-026340-2nf97zvc	287	1	2020	2020	CD
cord-026340-2nf97zvc	287	2	)	)	-RRB-
cord-026340-2nf97zvc	288	1	16	16	CD
cord-026340-2nf97zvc	288	2	CQ	CQ	NNP
cord-026340-2nf97zvc	288	3	(	(	-LRB-
cord-026340-2nf97zvc	288	4	500	500	CD
cord-026340-2nf97zvc	288	5	mg	mg	NNS
cord-026340-2nf97zvc	288	6	)	)	-RRB-
cord-026340-2nf97zvc	288	7	or	or	CC
cord-026340-2nf97zvc	288	8	HCQ	HCQ	NNP
cord-026340-2nf97zvc	288	9	(	(	-LRB-
cord-026340-2nf97zvc	288	10	1200	1200	CD
cord-026340-2nf97zvc	288	11	mg	mg	NN
cord-026340-2nf97zvc	288	12	)	)	-RRB-
cord-026340-2nf97zvc	289	1	Prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	289	2	Systematic	systematic	JJ
cord-026340-2nf97zvc	289	3	review	review	NN
cord-026340-2nf97zvc	289	4	of	of	IN
cord-026340-2nf97zvc	289	5	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	289	6	use	use	NN
cord-026340-2nf97zvc	289	7	in	in	IN
cord-026340-2nf97zvc	289	8	pregnant	pregnant	JJ
cord-026340-2nf97zvc	289	9	patients	patient	NNS
cord-026340-2nf97zvc	289	10	with	with	IN
cord-026340-2nf97zvc	289	11	autoimmune	autoimmune	JJ
cord-026340-2nf97zvc	289	12	diseases	disease	NNS
cord-026340-2nf97zvc	289	13	(	(	-LRB-
cord-026340-2nf97zvc	289	14	Shah	Shah	NNP
cord-026340-2nf97zvc	289	15	et	et	NNP
cord-026340-2nf97zvc	289	16	al	al	NNP
cord-026340-2nf97zvc	289	17	.	.	.
cord-026340-2nf97zvc	290	1	2020	2020	CD
cord-026340-2nf97zvc	290	2	)	)	-RRB-
cord-026340-2nf97zvc	291	1	17	17	CD
cord-026340-2nf97zvc	291	2	HCQ	HCQ	NNP
cord-026340-2nf97zvc	291	3	(	(	-LRB-
cord-026340-2nf97zvc	291	4	6	6	CD
cord-026340-2nf97zvc	291	5	mg	mg	NNP
cord-026340-2nf97zvc	291	6	/	/	SYM
cord-026340-2nf97zvc	291	7	kg	kg	NNP
cord-026340-2nf97zvc	291	8	/	/	SYM
cord-026340-2nf97zvc	291	9	day	day	NN
cord-026340-2nf97zvc	291	10	1	1	CD
cord-026340-2nf97zvc	291	11	(	(	-LRB-
cord-026340-2nf97zvc	291	12	loading	loading	NN
cord-026340-2nf97zvc	291	13	dose	dose	NN
cord-026340-2nf97zvc	291	14	)	)	-RRB-
cord-026340-2nf97zvc	291	15	followed	follow	VBN
cord-026340-2nf97zvc	291	16	by	by	IN
cord-026340-2nf97zvc	291	17	5	5	CD
cord-026340-2nf97zvc	291	18	mg	mg	NNP
cord-026340-2nf97zvc	291	19	/	/	SYM
cord-026340-2nf97zvc	291	20	kg	kg	NNP
cord-026340-2nf97zvc	291	21	/	/	SYM
cord-026340-2nf97zvc	291	22	day	day	NN
cord-026340-2nf97zvc	291	23	)	)	-RRB-
cord-026340-2nf97zvc	291	24	,	,	,
cord-026340-2nf97zvc	291	25	with	with	IN
cord-026340-2nf97zvc	291	26	a	a	DT
cord-026340-2nf97zvc	291	27	maximum	maximum	JJ
cord-026340-2nf97zvc	291	28	limit	limit	NN
cord-026340-2nf97zvc	291	29	of	of	IN
cord-026340-2nf97zvc	291	30	600	600	CD
cord-026340-2nf97zvc	291	31	mg	mg	NNP
cord-026340-2nf97zvc	291	32	/	/	SYM
cord-026340-2nf97zvc	291	33	day	day	NN
cord-026340-2nf97zvc	291	34	Post	Post	NNP
cord-026340-2nf97zvc	291	35	exposure	exposure	NN
cord-026340-2nf97zvc	291	36	Coalition	coalition	NN
cord-026340-2nf97zvc	291	37	:	:	:
cord-026340-2nf97zvc	291	38	advocacy	advocacy	NN
cord-026340-2nf97zvc	291	39	for	for	IN
cord-026340-2nf97zvc	291	40	prospective	prospective	JJ
cord-026340-2nf97zvc	291	41	clinical	clinical	JJ
cord-026340-2nf97zvc	291	42	trials	trial	NNS
cord-026340-2nf97zvc	291	43	to	to	TO
cord-026340-2nf97zvc	291	44	test	test	VB
cord-026340-2nf97zvc	291	45	the	the	DT
cord-026340-2nf97zvc	291	46	post	post	NN
cord-026340-2nf97zvc	291	47	exposure	exposure	NN
cord-026340-2nf97zvc	291	48	potential	potential	NN
cord-026340-2nf97zvc	291	49	of	of	IN
cord-026340-2nf97zvc	291	50	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	291	51	against	against	IN
cord-026340-2nf97zvc	291	52	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	291	53	(	(	-LRB-
cord-026340-2nf97zvc	291	54	Picot	Picot	NNP
cord-026340-2nf97zvc	291	55	2020	2020	CD
cord-026340-2nf97zvc	291	56	)	)	-RRB-
cord-026340-2nf97zvc	291	57	.	.	.
cord-026340-2nf97zvc	292	1	retained	retain	VBN
cord-026340-2nf97zvc	292	2	and	and	CC
cord-026340-2nf97zvc	292	3	the	the	DT
cord-026340-2nf97zvc	292	4	toxicity	toxicity	NN
cord-026340-2nf97zvc	292	5	of	of	IN
cord-026340-2nf97zvc	292	6	CQ	CQ	NNP
cord-026340-2nf97zvc	292	7	may	may	MD
cord-026340-2nf97zvc	292	8	be	be	VB
cord-026340-2nf97zvc	292	9	alleviated	alleviate	VBN
cord-026340-2nf97zvc	292	10	.	.	.
cord-026340-2nf97zvc	293	1	Table	table	NN
cord-026340-2nf97zvc	293	2	1	1	CD
cord-026340-2nf97zvc	293	3	gives	give	VBZ
cord-026340-2nf97zvc	293	4	framework	framework	NN
cord-026340-2nf97zvc	293	5	of	of	IN
cord-026340-2nf97zvc	293	6	some	some	DT
cord-026340-2nf97zvc	293	7	of	of	IN
cord-026340-2nf97zvc	293	8	the	the	DT
cord-026340-2nf97zvc	293	9	research	research	NN
cord-026340-2nf97zvc	293	10	work	work	NN
cord-026340-2nf97zvc	293	11	published	publish	VBN
cord-026340-2nf97zvc	293	12	using	use	VBG
cord-026340-2nf97zvc	293	13	CQ	CQ	NNP
cord-026340-2nf97zvc	293	14	or	or	CC
cord-026340-2nf97zvc	293	15	HCQ	HCQ	NNP
cord-026340-2nf97zvc	293	16	with	with	IN
cord-026340-2nf97zvc	293	17	suggested	suggest	VBN
cord-026340-2nf97zvc	293	18	drug	drug	NN
cord-026340-2nf97zvc	293	19	doses	dose	NNS
cord-026340-2nf97zvc	293	20	for	for	IN
cord-026340-2nf97zvc	293	21	treatment	treatment	NN
cord-026340-2nf97zvc	293	22	regimen	regimen	NN
cord-026340-2nf97zvc	293	23	of	of	IN
cord-026340-2nf97zvc	293	24	COVID	COVID	NNP
cord-026340-2nf97zvc	293	25	19	19	CD
cord-026340-2nf97zvc	293	26	.	.	.
cord-026340-2nf97zvc	294	1	While	while	IN
cord-026340-2nf97zvc	294	2	this	this	DT
cord-026340-2nf97zvc	294	3	article	article	NN
cord-026340-2nf97zvc	294	4	was	be	VBD
cord-026340-2nf97zvc	294	5	under	under	IN
cord-026340-2nf97zvc	294	6	revision	revision	NN
cord-026340-2nf97zvc	294	7	,	,	,
cord-026340-2nf97zvc	294	8	we	-PRON-	PRP
cord-026340-2nf97zvc	294	9	came	come	VBD
cord-026340-2nf97zvc	294	10	across	across	IN
cord-026340-2nf97zvc	294	11	an	an	DT
cord-026340-2nf97zvc	294	12	extensive	extensive	JJ
cord-026340-2nf97zvc	294	13	collaborative	collaborative	JJ
cord-026340-2nf97zvc	294	14	study	study	NN
cord-026340-2nf97zvc	294	15	by	by	IN
cord-026340-2nf97zvc	294	16	Picot	Picot	NNP
cord-026340-2nf97zvc	294	17	(	(	-LRB-
cord-026340-2nf97zvc	294	18	2020	2020	CD
cord-026340-2nf97zvc	294	19	)	)	-RRB-
cord-026340-2nf97zvc	294	20	,	,	,
cord-026340-2nf97zvc	294	21	which	which	WDT
cord-026340-2nf97zvc	294	22	stated	state	VBD
cord-026340-2nf97zvc	294	23	that	that	IN
cord-026340-2nf97zvc	294	24	in	in	IN
cord-026340-2nf97zvc	294	25	the	the	DT
cord-026340-2nf97zvc	294	26	current	current	JJ
cord-026340-2nf97zvc	294	27	context	context	NN
cord-026340-2nf97zvc	294	28	of	of	IN
cord-026340-2nf97zvc	294	29	the	the	DT
cord-026340-2nf97zvc	294	30	severe	severe	JJ
cord-026340-2nf97zvc	294	31	worldwide	worldwide	JJ
cord-026340-2nf97zvc	294	32	health	health	NN
cord-026340-2nf97zvc	294	33	emergency	emergency	NN
cord-026340-2nf97zvc	294	34	,	,	,
cord-026340-2nf97zvc	294	35	it	-PRON-	PRP
cord-026340-2nf97zvc	294	36	is	be	VBZ
cord-026340-2nf97zvc	294	37	practical	practical	JJ
cord-026340-2nf97zvc	294	38	for	for	IN
cord-026340-2nf97zvc	294	39	clinicians	clinician	NNS
cord-026340-2nf97zvc	294	40	to	to	TO
cord-026340-2nf97zvc	294	41	use	use	VB
cord-026340-2nf97zvc	294	42	HCQ	HCQ	NNP
cord-026340-2nf97zvc	294	43	even	even	RB
cord-026340-2nf97zvc	294	44	if	if	IN
cord-026340-2nf97zvc	294	45	it	-PRON-	PRP
cord-026340-2nf97zvc	294	46	can	can	MD
cord-026340-2nf97zvc	294	47	only	only	RB
cord-026340-2nf97zvc	294	48	reduce	reduce	VB
cord-026340-2nf97zvc	294	49	viral	viral	JJ
cord-026340-2nf97zvc	294	50	load	load	NN
cord-026340-2nf97zvc	294	51	by	by	IN
cord-026340-2nf97zvc	294	52	10	10	CD
cord-026340-2nf97zvc	294	53	-	-	SYM
cord-026340-2nf97zvc	294	54	30	30	CD
cord-026340-2nf97zvc	294	55	%	%	NN
cord-026340-2nf97zvc	294	56	.	.	.
cord-026340-2nf97zvc	295	1	They	-PRON-	PRP
cord-026340-2nf97zvc	295	2	mentioned	mention	VBD
cord-026340-2nf97zvc	295	3	that	that	IN
cord-026340-2nf97zvc	295	4	these	these	DT
cord-026340-2nf97zvc	295	5	are	be	VBP
cord-026340-2nf97zvc	295	6	effective	effective	JJ
cord-026340-2nf97zvc	295	7	measures	measure	NNS
cord-026340-2nf97zvc	295	8	in	in	IN
cord-026340-2nf97zvc	295	9	reducing	reduce	VBG
cord-026340-2nf97zvc	295	10	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	295	11	spread	spread	NN
cord-026340-2nf97zvc	295	12	and	and	CC
cord-026340-2nf97zvc	295	13	improving	improve	VBG
cord-026340-2nf97zvc	295	14	clinical	clinical	JJ
cord-026340-2nf97zvc	295	15	outcome	outcome	NN
cord-026340-2nf97zvc	295	16	in	in	IN
cord-026340-2nf97zvc	295	17	health	health	NN
cord-026340-2nf97zvc	295	18	care	care	NN
cord-026340-2nf97zvc	295	19	workers	worker	NNS
cord-026340-2nf97zvc	295	20	.	.	.
cord-026340-2nf97zvc	296	1	They	-PRON-	PRP
cord-026340-2nf97zvc	296	2	have	have	VBP
cord-026340-2nf97zvc	296	3	stated	state	VBN
cord-026340-2nf97zvc	296	4	that	that	IN
cord-026340-2nf97zvc	296	5	HCQ	HCQ	NNP
cord-026340-2nf97zvc	296	6	at	at	IN
cord-026340-2nf97zvc	296	7	doses	dose	NNS
cord-026340-2nf97zvc	296	8	matching	match	VBG
cord-026340-2nf97zvc	296	9	that	that	DT
cord-026340-2nf97zvc	296	10	of	of	IN
cord-026340-2nf97zvc	296	11	the	the	DT
cord-026340-2nf97zvc	296	12	standard	standard	JJ
cord-026340-2nf97zvc	296	13	treatment	treatment	NN
cord-026340-2nf97zvc	296	14	of	of	IN
cord-026340-2nf97zvc	296	15	Systemic	Systemic	NNP
cord-026340-2nf97zvc	296	16	Lupus	Lupus	NNP
cord-026340-2nf97zvc	296	17	erythematous	erythematous	JJ
cord-026340-2nf97zvc	296	18	[	[	-LRB-
cord-026340-2nf97zvc	296	19	which	which	WDT
cord-026340-2nf97zvc	296	20	has	have	VBZ
cord-026340-2nf97zvc	296	21	proven	prove	VBN
cord-026340-2nf97zvc	296	22	safety	safety	NN
cord-026340-2nf97zvc	296	23	and	and	CC
cord-026340-2nf97zvc	296	24	efficacy	efficacy	NN
cord-026340-2nf97zvc	296	25	in	in	IN
cord-026340-2nf97zvc	296	26	terms	term	NNS
cord-026340-2nf97zvc	296	27	of	of	IN
cord-026340-2nf97zvc	296	28	HCQ	HCQ	NNP
cord-026340-2nf97zvc	296	29	blood	blood	NN
cord-026340-2nf97zvc	296	30	and	and	CC
cord-026340-2nf97zvc	296	31	tissue	tissue	NN
cord-026340-2nf97zvc	296	32	concentration	concentration	NN
cord-026340-2nf97zvc	296	33	adapted	adapt	VBN
cord-026340-2nf97zvc	296	34	to	to	TO
cord-026340-2nf97zvc	296	35	bodyweight	bodyweight	VB
cord-026340-2nf97zvc	296	36	at	at	IN
cord-026340-2nf97zvc	296	37	6	6	CD
cord-026340-2nf97zvc	296	38	mg	mg	NN
cord-026340-2nf97zvc	296	39	/	/	SYM
cord-026340-2nf97zvc	296	40	kg	kg	NNP
cord-026340-2nf97zvc	296	41	/	/	SYM
cord-026340-2nf97zvc	296	42	day	day	NN
cord-026340-2nf97zvc	296	43	1	1	CD
cord-026340-2nf97zvc	296	44	(	(	-LRB-
cord-026340-2nf97zvc	296	45	loading	loading	NN
cord-026340-2nf97zvc	296	46	dose	dose	NN
cord-026340-2nf97zvc	296	47	)	)	-RRB-
cord-026340-2nf97zvc	296	48	followed	follow	VBN
cord-026340-2nf97zvc	296	49	by	by	IN
cord-026340-2nf97zvc	296	50	5	5	CD
cord-026340-2nf97zvc	296	51	mg	mg	NNP
cord-026340-2nf97zvc	296	52	/	/	SYM
cord-026340-2nf97zvc	296	53	kg	kg	NNP
cord-026340-2nf97zvc	296	54	/	/	SYM
cord-026340-2nf97zvc	296	55	day	day	NN
cord-026340-2nf97zvc	296	56	,	,	,
cord-026340-2nf97zvc	296	57	with	with	IN
cord-026340-2nf97zvc	296	58	a	a	DT
cord-026340-2nf97zvc	296	59	maximum	maximum	JJ
cord-026340-2nf97zvc	296	60	limit	limit	NN
cord-026340-2nf97zvc	296	61	of	of	IN
cord-026340-2nf97zvc	296	62	600	600	CD
cord-026340-2nf97zvc	296	63	mg	mg	NNP
cord-026340-2nf97zvc	296	64	/	/	SYM
cord-026340-2nf97zvc	296	65	day	day	NN
cord-026340-2nf97zvc	296	66	in	in	IN
cord-026340-2nf97zvc	296	67	all	all	DT
cord-026340-2nf97zvc	296	68	cases	case	NNS
cord-026340-2nf97zvc	296	69	]	]	-RRB-
cord-026340-2nf97zvc	296	70	can	can	MD
cord-026340-2nf97zvc	296	71	be	be	VB
cord-026340-2nf97zvc	296	72	used	use	VBN
cord-026340-2nf97zvc	296	73	as	as	IN
cord-026340-2nf97zvc	296	74	a	a	DT
cord-026340-2nf97zvc	296	75	drug	drug	NN
cord-026340-2nf97zvc	296	76	for	for	IN
cord-026340-2nf97zvc	296	77	exposed	expose	VBN
cord-026340-2nf97zvc	296	78	people	people	NNS
cord-026340-2nf97zvc	296	79	.	.	.
cord-026340-2nf97zvc	297	1	The	the	DT
cord-026340-2nf97zvc	297	2	duration	duration	NN
cord-026340-2nf97zvc	297	3	of	of	IN
cord-026340-2nf97zvc	297	4	HCQ	HCQ	NNP
cord-026340-2nf97zvc	297	5	treatment	treatment	NN
cord-026340-2nf97zvc	297	6	can	can	MD
cord-026340-2nf97zvc	297	7	be	be	VB
cord-026340-2nf97zvc	297	8	as	as	RB
cord-026340-2nf97zvc	297	9	long	long	RB
cord-026340-2nf97zvc	297	10	as	as	IN
cord-026340-2nf97zvc	297	11	contact	contact	NN
cord-026340-2nf97zvc	297	12	with	with	IN
cord-026340-2nf97zvc	297	13	a	a	DT
cord-026340-2nf97zvc	297	14	positive	positive	JJ
cord-026340-2nf97zvc	297	15	patient	patient	NN
cord-026340-2nf97zvc	297	16	lasts	last	VBZ
cord-026340-2nf97zvc	297	17	.	.	.
cord-026340-2nf97zvc	298	1	In	in	IN
cord-026340-2nf97zvc	298	2	the	the	DT
cord-026340-2nf97zvc	298	3	case	case	NN
cord-026340-2nf97zvc	298	4	of	of	IN
cord-026340-2nf97zvc	298	5	repeated	repeat	VBN
cord-026340-2nf97zvc	298	6	exposure	exposure	NN
cord-026340-2nf97zvc	298	7	to	to	IN
cord-026340-2nf97zvc	298	8	virus	virus	NN
cord-026340-2nf97zvc	298	9	,	,	,
cord-026340-2nf97zvc	298	10	then	then	RB
cord-026340-2nf97zvc	298	11	treatment	treatment	NN
cord-026340-2nf97zvc	298	12	is	be	VBZ
cord-026340-2nf97zvc	298	13	suggested	suggest	VBN
cord-026340-2nf97zvc	298	14	to	to	TO
cord-026340-2nf97zvc	298	15	be	be	VB
cord-026340-2nf97zvc	298	16	for	for	IN
cord-026340-2nf97zvc	298	17	a	a	DT
cord-026340-2nf97zvc	298	18	min	min	NN
cord-026340-2nf97zvc	298	19	of	of	IN
cord-026340-2nf97zvc	298	20	10	10	CD
cord-026340-2nf97zvc	298	21	days	day	NNS
cord-026340-2nf97zvc	298	22	so	so	IN
cord-026340-2nf97zvc	298	23	that	that	IN
cord-026340-2nf97zvc	298	24	there	there	EX
cord-026340-2nf97zvc	298	25	is	be	VBZ
cord-026340-2nf97zvc	298	26	a	a	DT
cord-026340-2nf97zvc	298	27	steady	steady	JJ
cord-026340-2nf97zvc	298	28	state	state	NN
cord-026340-2nf97zvc	298	29	of	of	IN
cord-026340-2nf97zvc	298	30	drug	drug	NN
cord-026340-2nf97zvc	298	31	concentration	concentration	NN
cord-026340-2nf97zvc	298	32	in	in	IN
cord-026340-2nf97zvc	298	33	blood	blood	NN
cord-026340-2nf97zvc	298	34	(	(	-LRB-
cord-026340-2nf97zvc	298	35	Picot	Picot	NNP
cord-026340-2nf97zvc	298	36	2020	2020	CD
cord-026340-2nf97zvc	298	37	)	)	-RRB-
cord-026340-2nf97zvc	298	38	.	.	.
cord-026340-2nf97zvc	299	1	We	-PRON-	PRP
cord-026340-2nf97zvc	299	2	also	also	RB
cord-026340-2nf97zvc	299	3	include	include	VBP
cord-026340-2nf97zvc	299	4	in	in	IN
cord-026340-2nf97zvc	299	5	this	this	DT
cord-026340-2nf97zvc	299	6	article	article	NN
cord-026340-2nf97zvc	299	7	some	some	DT
cord-026340-2nf97zvc	299	8	details	detail	NNS
cord-026340-2nf97zvc	299	9	of	of	IN
cord-026340-2nf97zvc	299	10	our	-PRON-	PRP$
cord-026340-2nf97zvc	299	11	pilot	pilot	NN
cord-026340-2nf97zvc	299	12	study	study	NN
cord-026340-2nf97zvc	299	13	where	where	WRB
cord-026340-2nf97zvc	299	14	we	-PRON-	PRP
cord-026340-2nf97zvc	299	15	tested	test	VBD
cord-026340-2nf97zvc	299	16	the	the	DT
cord-026340-2nf97zvc	299	17	effect	effect	NN
cord-026340-2nf97zvc	299	18	of	of	IN
cord-026340-2nf97zvc	299	19	a	a	DT
cord-026340-2nf97zvc	299	20	combination	combination	NN
cord-026340-2nf97zvc	299	21	of	of	IN
cord-026340-2nf97zvc	299	22	CQ	CQ	NNP
cord-026340-2nf97zvc	299	23	(	(	-LRB-
cord-026340-2nf97zvc	299	24	Sigma	Sigma	NNP
cord-026340-2nf97zvc	299	25	Aldrich	Aldrich	NNP
cord-026340-2nf97zvc	299	26	,	,	,
cord-026340-2nf97zvc	299	27	USA	USA	NNP
cord-026340-2nf97zvc	299	28	)	)	-RRB-
cord-026340-2nf97zvc	299	29	and	and	CC
cord-026340-2nf97zvc	299	30	betulinic	betulinic	JJ
cord-026340-2nf97zvc	299	31	acid	acid	NN
cord-026340-2nf97zvc	299	32	(	(	-LRB-
cord-026340-2nf97zvc	299	33	Sigma	Sigma	NNP
cord-026340-2nf97zvc	299	34	Aldrich	Aldrich	NNP
cord-026340-2nf97zvc	299	35	,	,	,
cord-026340-2nf97zvc	299	36	USA	USA	NNP
cord-026340-2nf97zvc	299	37	)	)	-RRB-
cord-026340-2nf97zvc	299	38	on	on	IN
cord-026340-2nf97zvc	299	39	lysosomal	lysosomal	JJ
cord-026340-2nf97zvc	299	40	function	function	NN
cord-026340-2nf97zvc	299	41	in	in	IN
cord-026340-2nf97zvc	299	42	mononuclear	mononuclear	JJ
cord-026340-2nf97zvc	299	43	cells	cell	NNS
cord-026340-2nf97zvc	299	44	,	,	,
cord-026340-2nf97zvc	299	45	in	in	IN
cord-026340-2nf97zvc	299	46	the	the	DT
cord-026340-2nf97zvc	299	47	absence	absence	NN
cord-026340-2nf97zvc	299	48	of	of	IN
cord-026340-2nf97zvc	299	49	a	a	DT
cord-026340-2nf97zvc	299	50	pathogen	pathogen	NN
cord-026340-2nf97zvc	299	51	.	.	.
cord-026340-2nf97zvc	300	1	BA	BA	NNP
cord-026340-2nf97zvc	300	2	(	(	-LRB-
cord-026340-2nf97zvc	300	3	3β	3β	CD
cord-026340-2nf97zvc	300	4	-	-	HYPH
cord-026340-2nf97zvc	300	5	hydroxy	hydroxy	NN
cord-026340-2nf97zvc	300	6	-	-	HYPH
cord-026340-2nf97zvc	300	7	lup-20(29)-en-28-oic	lup-20(29)-en-28-oic	JJ
cord-026340-2nf97zvc	300	8	acid	acid	NN
cord-026340-2nf97zvc	300	9	)	)	-RRB-
cord-026340-2nf97zvc	300	10	is	be	VBZ
cord-026340-2nf97zvc	300	11	a	a	DT
cord-026340-2nf97zvc	300	12	triterpenoid	triterpenoid	NN
cord-026340-2nf97zvc	300	13	belonging	belong	VBG
cord-026340-2nf97zvc	300	14	to	to	IN
cord-026340-2nf97zvc	300	15	lupane	lupane	NNP
cord-026340-2nf97zvc	300	16	series	series	NNP
cord-026340-2nf97zvc	300	17	which	which	WDT
cord-026340-2nf97zvc	300	18	has	have	VBZ
cord-026340-2nf97zvc	300	19	a	a	DT
cord-026340-2nf97zvc	300	20	wide	wide	JJ
cord-026340-2nf97zvc	300	21	range	range	NN
cord-026340-2nf97zvc	300	22	of	of	IN
cord-026340-2nf97zvc	300	23	pharmacological	pharmacological	JJ
cord-026340-2nf97zvc	300	24	properties	property	NNS
cord-026340-2nf97zvc	300	25	like	like	IN
cord-026340-2nf97zvc	300	26	topoisomerase	topoisomerase	NN
cord-026340-2nf97zvc	300	27	inhibitory	inhibitory	JJ
cord-026340-2nf97zvc	300	28	potential	potential	NN
cord-026340-2nf97zvc	300	29	(	(	-LRB-
cord-026340-2nf97zvc	300	30	Chowdhuri	Chowdhuri	NNP
cord-026340-2nf97zvc	300	31	et	et	FW
cord-026340-2nf97zvc	300	32	al	al	NNP
cord-026340-2nf97zvc	300	33	.	.	.
cord-026340-2nf97zvc	300	34	2002	2002	CD
cord-026340-2nf97zvc	300	35	)	)	-RRB-
cord-026340-2nf97zvc	300	36	,	,	,
cord-026340-2nf97zvc	300	37	anti	anti	JJ
cord-026340-2nf97zvc	300	38	-	-	JJ
cord-026340-2nf97zvc	300	39	cancer	cancer	JJ
cord-026340-2nf97zvc	300	40	(	(	-LRB-
cord-026340-2nf97zvc	300	41	Ren	Ren	NNP
cord-026340-2nf97zvc	300	42	et	et	NNP
cord-026340-2nf97zvc	300	43	al	al	NNP
cord-026340-2nf97zvc	300	44	.	.	NNP
cord-026340-2nf97zvc	300	45	2010	2010	CD
cord-026340-2nf97zvc	300	46	)	)	-RRB-
cord-026340-2nf97zvc	300	47	,	,	,
cord-026340-2nf97zvc	300	48	anti	anti	JJ
cord-026340-2nf97zvc	300	49	-	-	JJ
cord-026340-2nf97zvc	300	50	malarial	malarial	JJ
cord-026340-2nf97zvc	300	51	(	(	-LRB-
cord-026340-2nf97zvc	300	52	de	de	FW
cord-026340-2nf97zvc	300	53	Sa	Sa	NNP
cord-026340-2nf97zvc	300	54	et	et	FW
cord-026340-2nf97zvc	300	55	al	al	NNP
cord-026340-2nf97zvc	300	56	.	.	.
cord-026340-2nf97zvc	300	57	2009	2009	CD
cord-026340-2nf97zvc	300	58	)	)	-RRB-
cord-026340-2nf97zvc	300	59	,	,	,
cord-026340-2nf97zvc	300	60	antiviral	antiviral	JJ
cord-026340-2nf97zvc	300	61	(	(	-LRB-
cord-026340-2nf97zvc	300	62	Pavlova	Pavlova	NNP
cord-026340-2nf97zvc	300	63	et	et	FW
cord-026340-2nf97zvc	300	64	al	al	NNP
cord-026340-2nf97zvc	300	65	.	.	NNP
cord-026340-2nf97zvc	300	66	2003	2003	CD
cord-026340-2nf97zvc	300	67	)	)	-RRB-
cord-026340-2nf97zvc	300	68	and	and	CC
cord-026340-2nf97zvc	300	69	anti	anti	JJ
cord-026340-2nf97zvc	300	70	-	-	JJ
cord-026340-2nf97zvc	300	71	inflammatory	inflammatory	JJ
cord-026340-2nf97zvc	300	72	properties	property	NNS
cord-026340-2nf97zvc	300	73	(	(	-LRB-
cord-026340-2nf97zvc	300	74	Chowdhuri	Chowdhuri	NNP
cord-026340-2nf97zvc	300	75	et	et	FW
cord-026340-2nf97zvc	300	76	al	al	NNP
cord-026340-2nf97zvc	300	77	.	.	NNP
cord-026340-2nf97zvc	300	78	2002	2002	CD
cord-026340-2nf97zvc	300	79	;	;	:
cord-026340-2nf97zvc	301	1	Vijayan	Vijayan	NNP
cord-026340-2nf97zvc	301	2	et	et	NNP
cord-026340-2nf97zvc	301	3	al	al	NNP
cord-026340-2nf97zvc	301	4	.	.	NNP
cord-026340-2nf97zvc	301	5	2011	2011	CD
cord-026340-2nf97zvc	301	6	)	)	-RRB-
cord-026340-2nf97zvc	301	7	.	.	.
cord-026340-2nf97zvc	302	1	BA	BA	NNP
cord-026340-2nf97zvc	302	2	can	can	MD
cord-026340-2nf97zvc	302	3	be	be	VB
cord-026340-2nf97zvc	302	4	extracted	extract	VBN
cord-026340-2nf97zvc	302	5	from	from	IN
cord-026340-2nf97zvc	302	6	bark	bark	NN
cord-026340-2nf97zvc	302	7	of	of	IN
cord-026340-2nf97zvc	302	8	birch	birch	NN
cord-026340-2nf97zvc	302	9	tree	tree	NN
cord-026340-2nf97zvc	302	10	and	and	CC
cord-026340-2nf97zvc	302	11	many	many	JJ
cord-026340-2nf97zvc	302	12	other	other	JJ
cord-026340-2nf97zvc	302	13	plant	plant	NN
cord-026340-2nf97zvc	302	14	sources	source	NNS
cord-026340-2nf97zvc	302	15	(	(	-LRB-
cord-026340-2nf97zvc	302	16	Moghaddami	Moghaddami	NNP
cord-026340-2nf97zvc	302	17	and	and	CC
cord-026340-2nf97zvc	302	18	Ahmad	Ahmad	NNP
cord-026340-2nf97zvc	302	19	2012	2012	CD
cord-026340-2nf97zvc	302	20	)	)	-RRB-
cord-026340-2nf97zvc	302	21	.	.	.
cord-026340-2nf97zvc	303	1	Purified	purify	VBN
cord-026340-2nf97zvc	303	2	form	form	NN
cord-026340-2nf97zvc	303	3	of	of	IN
cord-026340-2nf97zvc	303	4	botanicals	botanical	NNS
cord-026340-2nf97zvc	303	5	is	be	VBZ
cord-026340-2nf97zvc	303	6	a	a	DT
cord-026340-2nf97zvc	303	7	rich	rich	JJ
cord-026340-2nf97zvc	303	8	resource	resource	NN
cord-026340-2nf97zvc	303	9	for	for	IN
cord-026340-2nf97zvc	303	10	novel	novel	JJ
cord-026340-2nf97zvc	303	11	antiviral	antiviral	JJ
cord-026340-2nf97zvc	303	12	drugs	drug	NNS
cord-026340-2nf97zvc	303	13	as	as	IN
cord-026340-2nf97zvc	303	14	these	these	DT
cord-026340-2nf97zvc	303	15	can	can	MD
cord-026340-2nf97zvc	303	16	interact	interact	VB
cord-026340-2nf97zvc	303	17	with	with	IN
cord-026340-2nf97zvc	303	18	different	different	JJ
cord-026340-2nf97zvc	303	19	stages	stage	NNS
cord-026340-2nf97zvc	303	20	of	of	IN
cord-026340-2nf97zvc	303	21	the	the	DT
cord-026340-2nf97zvc	303	22	viral	viral	JJ
cord-026340-2nf97zvc	303	23	life	life	NN
cord-026340-2nf97zvc	303	24	cycle	cycle	NN
cord-026340-2nf97zvc	303	25	,	,	,
cord-026340-2nf97zvc	303	26	such	such	JJ
cord-026340-2nf97zvc	303	27	as	as	IN
cord-026340-2nf97zvc	303	28	viral	viral	JJ
cord-026340-2nf97zvc	303	29	entry	entry	NN
cord-026340-2nf97zvc	303	30	,	,	,
cord-026340-2nf97zvc	303	31	replication	replication	NN
cord-026340-2nf97zvc	303	32	,	,	,
cord-026340-2nf97zvc	303	33	assembly	assembly	NN
cord-026340-2nf97zvc	303	34	,	,	,
cord-026340-2nf97zvc	303	35	and	and	CC
cord-026340-2nf97zvc	303	36	release	release	NN
cord-026340-2nf97zvc	303	37	,	,	,
cord-026340-2nf97zvc	303	38	as	as	RB
cord-026340-2nf97zvc	303	39	well	well	RB
cord-026340-2nf97zvc	303	40	as	as	IN
cord-026340-2nf97zvc	303	41	on	on	IN
cord-026340-2nf97zvc	303	42	the	the	DT
cord-026340-2nf97zvc	303	43	targeting	targeting	NN
cord-026340-2nf97zvc	303	44	of	of	IN
cord-026340-2nf97zvc	303	45	virus	virus	NN
cord-026340-2nf97zvc	303	46	-	-	HYPH
cord-026340-2nf97zvc	303	47	host	host	NN
cord-026340-2nf97zvc	303	48	-	-	HYPH
cord-026340-2nf97zvc	303	49	specific	specific	JJ
cord-026340-2nf97zvc	303	50	interactions	interaction	NNS
cord-026340-2nf97zvc	303	51	.	.	.
cord-026340-2nf97zvc	304	1	CQ	CQ	NNP
cord-026340-2nf97zvc	304	2	is	be	VBZ
cord-026340-2nf97zvc	304	3	itself	-PRON-	PRP
cord-026340-2nf97zvc	304	4	a	a	DT
cord-026340-2nf97zvc	304	5	synthetic	synthetic	JJ
cord-026340-2nf97zvc	304	6	form	form	NN
cord-026340-2nf97zvc	304	7	of	of	IN
cord-026340-2nf97zvc	304	8	quinine	quinine	NN
cord-026340-2nf97zvc	304	9	isolated	isolate	VBN
cord-026340-2nf97zvc	304	10	from	from	IN
cord-026340-2nf97zvc	304	11	barks	bark	NNS
cord-026340-2nf97zvc	304	12	of	of	IN
cord-026340-2nf97zvc	304	13	barks	bark	NNS
cord-026340-2nf97zvc	304	14	of	of	IN
cord-026340-2nf97zvc	304	15	cinchona	cinchona	NN
cord-026340-2nf97zvc	304	16	trees	tree	NNS
cord-026340-2nf97zvc	304	17	native	native	JJ
cord-026340-2nf97zvc	304	18	to	to	IN
cord-026340-2nf97zvc	304	19	Peru	Peru	NNP
cord-026340-2nf97zvc	304	20	.	.	.
cord-026340-2nf97zvc	305	1	So	so	RB
cord-026340-2nf97zvc	305	2	,	,	,
cord-026340-2nf97zvc	305	3	it	-PRON-	PRP
cord-026340-2nf97zvc	305	4	was	be	VBD
cord-026340-2nf97zvc	305	5	of	of	IN
cord-026340-2nf97zvc	305	6	interest	interest	NN
cord-026340-2nf97zvc	305	7	to	to	TO
cord-026340-2nf97zvc	305	8	check	check	VB
cord-026340-2nf97zvc	305	9	whether	whether	IN
cord-026340-2nf97zvc	305	10	BA	BA	NNP
cord-026340-2nf97zvc	305	11	and	and	CC
cord-026340-2nf97zvc	305	12	CQ	CQ	NNP
cord-026340-2nf97zvc	305	13	exerted	exert	VBD
cord-026340-2nf97zvc	305	14	an	an	DT
cord-026340-2nf97zvc	305	15	additive	additive	NN
cord-026340-2nf97zvc	305	16	effect	effect	NN
cord-026340-2nf97zvc	305	17	on	on	IN
cord-026340-2nf97zvc	305	18	lysosomal	lysosomal	JJ
cord-026340-2nf97zvc	305	19	function	function	NN
cord-026340-2nf97zvc	305	20	.	.	.
cord-026340-2nf97zvc	306	1	Briefly	briefly	RB
cord-026340-2nf97zvc	306	2	,	,	,
cord-026340-2nf97zvc	306	3	mononuclear	mononuclear	NN
cord-026340-2nf97zvc	306	4	cells	cell	NNS
cord-026340-2nf97zvc	306	5	were	be	VBD
cord-026340-2nf97zvc	306	6	isolated	isolate	VBN
cord-026340-2nf97zvc	306	7	from	from	IN
cord-026340-2nf97zvc	306	8	healthy	healthy	JJ
cord-026340-2nf97zvc	306	9	volunteers	volunteer	NNS
cord-026340-2nf97zvc	306	10	by	by	IN
cord-026340-2nf97zvc	306	11	density	density	NN
cord-026340-2nf97zvc	306	12	gradient	gradient	NN
cord-026340-2nf97zvc	306	13	centrifugation	centrifugation	NN
cord-026340-2nf97zvc	306	14	as	as	IN
cord-026340-2nf97zvc	306	15	detailed	detail	VBN
cord-026340-2nf97zvc	306	16	in	in	IN
cord-026340-2nf97zvc	306	17	Vijayan	Vijayan	NNP
cord-026340-2nf97zvc	306	18	et	et	NNP
cord-026340-2nf97zvc	306	19	al	al	NNP
cord-026340-2nf97zvc	306	20	.	.	.
cord-026340-2nf97zvc	307	1	(	(	-LRB-
cord-026340-2nf97zvc	307	2	2011	2011	CD
cord-026340-2nf97zvc	307	3	)	)	-RRB-
cord-026340-2nf97zvc	307	4	.	.	.
cord-026340-2nf97zvc	308	1	Blood	blood	NN
cord-026340-2nf97zvc	308	2	collected	collect	VBN
cord-026340-2nf97zvc	308	3	on	on	IN
cord-026340-2nf97zvc	308	4	heparinized	heparinize	VBN
cord-026340-2nf97zvc	308	5	tubes	tube	NNS
cord-026340-2nf97zvc	308	6	were	be	VBD
cord-026340-2nf97zvc	308	7	loaded	load	VBN
cord-026340-2nf97zvc	308	8	on	on	IN
cord-026340-2nf97zvc	308	9	Histopaque-1077	Histopaque-1077	NNP
cord-026340-2nf97zvc	309	1	(	(	-LRB-
cord-026340-2nf97zvc	309	2	Sigma	Sigma	NNP
cord-026340-2nf97zvc	309	3	Aldrich	Aldrich	NNP
cord-026340-2nf97zvc	309	4	,	,	,
cord-026340-2nf97zvc	309	5	USA	USA	NNP
cord-026340-2nf97zvc	309	6	)	)	-RRB-
cord-026340-2nf97zvc	309	7	and	and	CC
cord-026340-2nf97zvc	309	8	centrifuged	centrifuge	VBD
cord-026340-2nf97zvc	309	9	at	at	IN
cord-026340-2nf97zvc	309	10	800	800	CD
cord-026340-2nf97zvc	309	11	rpm	rpm	NN
cord-026340-2nf97zvc	309	12	for	for	IN
cord-026340-2nf97zvc	309	13	30	30	CD
cord-026340-2nf97zvc	309	14	min	min	NN
cord-026340-2nf97zvc	309	15	.	.	.
cord-026340-2nf97zvc	310	1	The	the	DT
cord-026340-2nf97zvc	310	2	buffy	buffy	NNP
cord-026340-2nf97zvc	310	3	coat	coat	NN
cord-026340-2nf97zvc	310	4	layer	layer	NN
cord-026340-2nf97zvc	310	5	at	at	IN
cord-026340-2nf97zvc	310	6	interface	interface	NN
cord-026340-2nf97zvc	310	7	was	be	VBD
cord-026340-2nf97zvc	310	8	retrieved	retrieve	VBN
cord-026340-2nf97zvc	310	9	and	and	CC
cord-026340-2nf97zvc	310	10	plated	plate	VBN
cord-026340-2nf97zvc	310	11	on	on	IN
cord-026340-2nf97zvc	310	12	type	type	NN
cord-026340-2nf97zvc	310	13	I	-PRON-	PRP
cord-026340-2nf97zvc	310	14	collagen	collagen	NN
cord-026340-2nf97zvc	310	15	coated	coated	JJ
cord-026340-2nf97zvc	310	16	cell	cell	NN
cord-026340-2nf97zvc	310	17	culture	culture	NN
cord-026340-2nf97zvc	310	18	dishes	dish	NNS
cord-026340-2nf97zvc	310	19	containing	contain	VBG
cord-026340-2nf97zvc	310	20	RPMI-1640	rpmi-1640	NN
cord-026340-2nf97zvc	310	21	media	medium	NNS
cord-026340-2nf97zvc	310	22	containing	contain	VBG
cord-026340-2nf97zvc	310	23	10	10	CD
cord-026340-2nf97zvc	310	24	%	%	NN
cord-026340-2nf97zvc	310	25	FBS	FBS	NNP
cord-026340-2nf97zvc	310	26	.	.	.
cord-026340-2nf97zvc	311	1	After	after	IN
cord-026340-2nf97zvc	311	2	4	4	CD
cord-026340-2nf97zvc	311	3	h	h	NN
cord-026340-2nf97zvc	311	4	,	,	,
cord-026340-2nf97zvc	311	5	the	the	DT
cord-026340-2nf97zvc	311	6	media	medium	NNS
cord-026340-2nf97zvc	311	7	were	be	VBD
cord-026340-2nf97zvc	311	8	carefully	carefully	RB
cord-026340-2nf97zvc	311	9	changed	change	VBN
cord-026340-2nf97zvc	311	10	to	to	TO
cord-026340-2nf97zvc	311	11	remove	remove	VB
cord-026340-2nf97zvc	311	12	the	the	DT
cord-026340-2nf97zvc	311	13	floating	float	VBG
cord-026340-2nf97zvc	311	14	lymphocytes	lymphocyte	NNS
cord-026340-2nf97zvc	311	15	.	.	.
cord-026340-2nf97zvc	312	1	The	the	DT
cord-026340-2nf97zvc	312	2	adherent	adherent	JJ
cord-026340-2nf97zvc	312	3	mononuclear	mononuclear	NN
cord-026340-2nf97zvc	312	4	cells	cell	NNS
cord-026340-2nf97zvc	312	5	were	be	VBD
cord-026340-2nf97zvc	312	6	cell	cell	NN
cord-026340-2nf97zvc	312	7	cultured	culture	VBN
cord-026340-2nf97zvc	312	8	till	till	IN
cord-026340-2nf97zvc	312	9	plate	plate	NN
cord-026340-2nf97zvc	312	10	reached	reach	VBD
cord-026340-2nf97zvc	312	11	75	75	CD
cord-026340-2nf97zvc	312	12	-	-	SYM
cord-026340-2nf97zvc	312	13	80	80	CD
cord-026340-2nf97zvc	312	14	%	%	NN
cord-026340-2nf97zvc	312	15	confluency	confluency	NN
cord-026340-2nf97zvc	312	16	(	(	-LRB-
cord-026340-2nf97zvc	312	17	2	2	CD
cord-026340-2nf97zvc	312	18	-	-	SYM
cord-026340-2nf97zvc	312	19	3	3	CD
cord-026340-2nf97zvc	312	20	days	day	NNS
cord-026340-2nf97zvc	312	21	)	)	-RRB-
cord-026340-2nf97zvc	312	22	.	.	.
cord-026340-2nf97zvc	313	1	Cells	cell	NNS
cord-026340-2nf97zvc	313	2	were	be	VBD
cord-026340-2nf97zvc	313	3	then	then	RB
cord-026340-2nf97zvc	313	4	shifted	shift	VBN
cord-026340-2nf97zvc	313	5	to	to	IN
cord-026340-2nf97zvc	313	6	media	medium	NNS
cord-026340-2nf97zvc	313	7	with	with	IN
cord-026340-2nf97zvc	313	8	autologous	autologous	JJ
cord-026340-2nf97zvc	313	9	serum	serum	NN
cord-026340-2nf97zvc	313	10	and	and	CC
cord-026340-2nf97zvc	313	11	exposed	expose	VBN
cord-026340-2nf97zvc	313	12	to	to	IN
cord-026340-2nf97zvc	313	13	a	a	DT
cord-026340-2nf97zvc	313	14	standardized	standardized	JJ
cord-026340-2nf97zvc	313	15	concentration	concentration	NN
cord-026340-2nf97zvc	313	16	of	of	IN
cord-026340-2nf97zvc	313	17	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	313	18	(	(	-LRB-
cord-026340-2nf97zvc	313	19	CQ	CQ	NNP
cord-026340-2nf97zvc	313	20	,	,	,
cord-026340-2nf97zvc	313	21	2.5	2.5	CD
cord-026340-2nf97zvc	313	22	micromolar	micromolar	JJ
cord-026340-2nf97zvc	313	23	)	)	-RRB-
cord-026340-2nf97zvc	313	24	or	or	CC
cord-026340-2nf97zvc	313	25	betulinic	betulinic	JJ
cord-026340-2nf97zvc	313	26	acid	acid	NN
cord-026340-2nf97zvc	313	27	(	(	-LRB-
cord-026340-2nf97zvc	313	28	BA	BA	NNP
cord-026340-2nf97zvc	313	29	,	,	,
cord-026340-2nf97zvc	313	30	10	10	CD
cord-026340-2nf97zvc	313	31	ng	ng	NN
cord-026340-2nf97zvc	313	32	/	/	SYM
cord-026340-2nf97zvc	313	33	ml	ml	NN
cord-026340-2nf97zvc	313	34	)	)	-RRB-
cord-026340-2nf97zvc	313	35	and	and	CC
cord-026340-2nf97zvc	313	36	a	a	DT
cord-026340-2nf97zvc	313	37	combination	combination	NN
cord-026340-2nf97zvc	313	38	of	of	IN
cord-026340-2nf97zvc	313	39	both	both	DT
cord-026340-2nf97zvc	313	40	(	(	-LRB-
cord-026340-2nf97zvc	313	41	CQ	CQ	NNP
cord-026340-2nf97zvc	313	42	+	+	CC
cord-026340-2nf97zvc	313	43	BA	BA	NNP
cord-026340-2nf97zvc	313	44	)	)	-RRB-
cord-026340-2nf97zvc	313	45	.	.	.
cord-026340-2nf97zvc	314	1	BA	BA	NNP
cord-026340-2nf97zvc	314	2	was	be	VBD
cord-026340-2nf97zvc	314	3	pre	pre	VBN
cord-026340-2nf97zvc	314	4	-	-	VBN
cord-026340-2nf97zvc	314	5	treated	treat	VBN
cord-026340-2nf97zvc	314	6	for	for	IN
cord-026340-2nf97zvc	314	7	20	20	CD
cord-026340-2nf97zvc	314	8	min	min	NN
cord-026340-2nf97zvc	314	9	prior	prior	RB
cord-026340-2nf97zvc	314	10	to	to	IN
cord-026340-2nf97zvc	314	11	CQ	CQ	NNP
cord-026340-2nf97zvc	314	12	addition	addition	NN
cord-026340-2nf97zvc	314	13	that	that	WDT
cord-026340-2nf97zvc	314	14	was	be	VBD
cord-026340-2nf97zvc	314	15	for	for	IN
cord-026340-2nf97zvc	314	16	4	4	CD
cord-026340-2nf97zvc	314	17	h.	h.	NNP
cord-026340-2nf97zvc	314	18	β	β	NNP
cord-026340-2nf97zvc	314	19	-	-	HYPH
cord-026340-2nf97zvc	314	20	hexosaminidase	hexosaminidase	NNP
cord-026340-2nf97zvc	314	21	activity	activity	NN
cord-026340-2nf97zvc	314	22	was	be	VBD
cord-026340-2nf97zvc	314	23	determined	determine	VBN
cord-026340-2nf97zvc	314	24	in	in	IN
cord-026340-2nf97zvc	314	25	cell	cell	NN
cord-026340-2nf97zvc	314	26	lysates	lysate	NNS
cord-026340-2nf97zvc	314	27	by	by	IN
cord-026340-2nf97zvc	314	28	colorimetric	colorimetric	JJ
cord-026340-2nf97zvc	314	29	assay	assay	NN
cord-026340-2nf97zvc	314	30	as	as	IN
cord-026340-2nf97zvc	314	31	previously	previously	RB
cord-026340-2nf97zvc	314	32	described	describe	VBN
cord-026340-2nf97zvc	314	33	by	by	IN
cord-026340-2nf97zvc	314	34	Lew	Lew	NNP
cord-026340-2nf97zvc	314	35	and	and	CC
cord-026340-2nf97zvc	314	36	Rarrazzi	Rarrazzi	NNP
cord-026340-2nf97zvc	314	37	(	(	-LRB-
cord-026340-2nf97zvc	314	38	1991	1991	CD
cord-026340-2nf97zvc	314	39	)	)	-RRB-
cord-026340-2nf97zvc	314	40	.	.	.
cord-026340-2nf97zvc	315	1	Lysed	lysed	JJ
cord-026340-2nf97zvc	315	2	cell	cell	NN
cord-026340-2nf97zvc	315	3	extracts	extract	NNS
cord-026340-2nf97zvc	315	4	prepared	prepare	VBN
cord-026340-2nf97zvc	315	5	by	by	IN
cord-026340-2nf97zvc	315	6	repeated	repeated	JJ
cord-026340-2nf97zvc	315	7	freeze	freeze	NN
cord-026340-2nf97zvc	315	8	-	-	HYPH
cord-026340-2nf97zvc	315	9	thaw	thaw	VB
cord-026340-2nf97zvc	315	10	cycles	cycle	NNS
cord-026340-2nf97zvc	315	11	from	from	IN
cord-026340-2nf97zvc	315	12	basal	basal	NN
cord-026340-2nf97zvc	315	13	,	,	,
cord-026340-2nf97zvc	315	14	CQ-	CQ-	NNP
cord-026340-2nf97zvc	315	15	,	,	,
cord-026340-2nf97zvc	315	16	BA	BA	NNP
cord-026340-2nf97zvc	315	17	-	-	HYPH
cord-026340-2nf97zvc	315	18	and	and	CC
cord-026340-2nf97zvc	315	19	CQ	CQ	NNP
cord-026340-2nf97zvc	315	20	+	+	CC
cord-026340-2nf97zvc	315	21	BA	BA	NNP
cord-026340-2nf97zvc	315	22	-	-	HYPH
cord-026340-2nf97zvc	315	23	treated	treat	VBN
cord-026340-2nf97zvc	315	24	cell	cell	NN
cord-026340-2nf97zvc	315	25	cultures	culture	NNS
cord-026340-2nf97zvc	315	26	were	be	VBD
cord-026340-2nf97zvc	315	27	incubated	incubate	VBN
cord-026340-2nf97zvc	315	28	with	with	IN
cord-026340-2nf97zvc	315	29	p	p	NN
cord-026340-2nf97zvc	315	30	-	-	HYPH
cord-026340-2nf97zvc	315	31	Nitrophenyl-2-deoxy	Nitrophenyl-2-deoxy	NNP
cord-026340-2nf97zvc	315	32	-	-	HYPH
cord-026340-2nf97zvc	315	33	β	β	NNP
cord-026340-2nf97zvc	315	34	-	-	HYPH
cord-026340-2nf97zvc	315	35	d	d	NN
cord-026340-2nf97zvc	315	36	-	-	HYPH
cord-026340-2nf97zvc	315	37	glucosaminide	glucosaminide	NN
cord-026340-2nf97zvc	315	38	(	(	-LRB-
cord-026340-2nf97zvc	315	39	5	5	CD
cord-026340-2nf97zvc	315	40	mM	mm	CD
cord-026340-2nf97zvc	315	41	)	)	-RRB-
cord-026340-2nf97zvc	315	42	in	in	IN
cord-026340-2nf97zvc	315	43	0.1-M	0.1-m	CD
cord-026340-2nf97zvc	315	44	citrate	citrate	NN
cord-026340-2nf97zvc	315	45	/	/	SYM
cord-026340-2nf97zvc	315	46	phosphate	phosphate	NN
cord-026340-2nf97zvc	315	47	buffer	buffer	NN
cord-026340-2nf97zvc	315	48	,	,	,
cord-026340-2nf97zvc	315	49	pH	pH	NNP
cord-026340-2nf97zvc	315	50	4.5	4.5	CD
cord-026340-2nf97zvc	315	51	for	for	IN
cord-026340-2nf97zvc	315	52	1	1	CD
cord-026340-2nf97zvc	315	53	h.	h.	NN
cord-026340-2nf97zvc	316	1	The	the	DT
cord-026340-2nf97zvc	316	2	p	p	NN
cord-026340-2nf97zvc	316	3	-	-	HYPH
cord-026340-2nf97zvc	316	4	nitrophenol	nitrophenol	NN
cord-026340-2nf97zvc	316	5	released	release	VBN
cord-026340-2nf97zvc	316	6	by	by	IN
cord-026340-2nf97zvc	316	7	the	the	DT
cord-026340-2nf97zvc	316	8	enzyme	enzyme	NN
cord-026340-2nf97zvc	316	9	-	-	HYPH
cord-026340-2nf97zvc	316	10	dependent	dependent	JJ
cord-026340-2nf97zvc	316	11	hydrolysis	hydrolysis	NN
cord-026340-2nf97zvc	316	12	of	of	IN
cord-026340-2nf97zvc	316	13	the	the	DT
cord-026340-2nf97zvc	316	14	substrate	substrate	NN
cord-026340-2nf97zvc	316	15	was	be	VBD
cord-026340-2nf97zvc	316	16	quantified	quantify	VBN
cord-026340-2nf97zvc	316	17	spectrophotometrically	spectrophotometrically	RB
cord-026340-2nf97zvc	317	1	(	(	-LRB-
cord-026340-2nf97zvc	317	2	Shimadzu	Shimadzu	NNP
cord-026340-2nf97zvc	317	3	,	,	,
cord-026340-2nf97zvc	317	4	Japan	Japan	NNP
cord-026340-2nf97zvc	317	5	)	)	-RRB-
cord-026340-2nf97zvc	317	6	at	at	IN
cord-026340-2nf97zvc	317	7	405-nm	405-nm	CD
cord-026340-2nf97zvc	317	8	wavelength	wavelength	NN
cord-026340-2nf97zvc	317	9	.	.	.
cord-026340-2nf97zvc	318	1	Units	unit	NNS
cord-026340-2nf97zvc	318	2	of	of	IN
cord-026340-2nf97zvc	318	3	activity	activity	NN
cord-026340-2nf97zvc	318	4	were	be	VBD
cord-026340-2nf97zvc	318	5	defined	define	VBN
cord-026340-2nf97zvc	318	6	as	as	IN
cord-026340-2nf97zvc	318	7	nanomoles	nanomole	NNS
cord-026340-2nf97zvc	318	8	of	of	IN
cord-026340-2nf97zvc	318	9	substrate	substrate	NN
cord-026340-2nf97zvc	318	10	per	per	IN
cord-026340-2nf97zvc	318	11	hour	hour	NN
cord-026340-2nf97zvc	318	12	per	per	IN
cord-026340-2nf97zvc	318	13	mg	mg	NN
cord-026340-2nf97zvc	318	14	protein	protein	NN
cord-026340-2nf97zvc	318	15	.	.	.
cord-026340-2nf97zvc	319	1	Results	result	NNS
cord-026340-2nf97zvc	319	2	of	of	IN
cord-026340-2nf97zvc	319	3	the	the	DT
cord-026340-2nf97zvc	319	4	study	study	NN
cord-026340-2nf97zvc	319	5	demonstrate	demonstrate	VBP
cord-026340-2nf97zvc	319	6	that	that	IN
cord-026340-2nf97zvc	319	7	a	a	DT
cord-026340-2nf97zvc	319	8	combination	combination	NN
cord-026340-2nf97zvc	319	9	of	of	IN
cord-026340-2nf97zvc	319	10	BA	BA	NNP
cord-026340-2nf97zvc	319	11	and	and	CC
cord-026340-2nf97zvc	319	12	CQ	CQ	NNP
cord-026340-2nf97zvc	319	13	has	have	VBZ
cord-026340-2nf97zvc	319	14	greater	great	JJR
cord-026340-2nf97zvc	319	15	effect	effect	NN
cord-026340-2nf97zvc	319	16	in	in	IN
cord-026340-2nf97zvc	319	17	reducing	reduce	VBG
cord-026340-2nf97zvc	319	18	lysosomal	lysosomal	JJ
cord-026340-2nf97zvc	319	19	activity	activity	NN
cord-026340-2nf97zvc	319	20	as	as	IN
cord-026340-2nf97zvc	319	21	compared	compare	VBN
cord-026340-2nf97zvc	319	22	to	to	IN
cord-026340-2nf97zvc	319	23	CQ	CQ	NNP
cord-026340-2nf97zvc	319	24	or	or	CC
cord-026340-2nf97zvc	319	25	BA	BA	NNP
cord-026340-2nf97zvc	319	26	(	(	-LRB-
cord-026340-2nf97zvc	319	27	Fig	Fig	NNP
cord-026340-2nf97zvc	319	28	.	.	NNP
cord-026340-2nf97zvc	319	29	2	2	CD
cord-026340-2nf97zvc	319	30	)	)	-RRB-
cord-026340-2nf97zvc	319	31	.	.	.
cord-026340-2nf97zvc	320	1	This	this	DT
cord-026340-2nf97zvc	320	2	is	be	VBZ
cord-026340-2nf97zvc	320	3	a	a	DT
cord-026340-2nf97zvc	320	4	pilot	pilot	NN
cord-026340-2nf97zvc	320	5	experiment	experiment	NN
cord-026340-2nf97zvc	320	6	conducted	conduct	VBN
cord-026340-2nf97zvc	320	7	in	in	IN
cord-026340-2nf97zvc	320	8	the	the	DT
cord-026340-2nf97zvc	320	9	absence	absence	NN
cord-026340-2nf97zvc	320	10	of	of	IN
cord-026340-2nf97zvc	320	11	a	a	DT
cord-026340-2nf97zvc	320	12	cargo	cargo	NN
cord-026340-2nf97zvc	320	13	.	.	.
cord-026340-2nf97zvc	321	1	CQ	CQ	NNP
cord-026340-2nf97zvc	321	2	is	be	VBZ
cord-026340-2nf97zvc	321	3	known	know	VBN
cord-026340-2nf97zvc	321	4	for	for	IN
cord-026340-2nf97zvc	321	5	inhibiting	inhibit	VBG
cord-026340-2nf97zvc	321	6	autophagy	autophagy	NN
cord-026340-2nf97zvc	321	7	by	by	IN
cord-026340-2nf97zvc	321	8	impairing	impair	VBG
cord-026340-2nf97zvc	321	9	autophagosome	autophagosome	JJ
cord-026340-2nf97zvc	321	10	fusion	fusion	NN
cord-026340-2nf97zvc	321	11	with	with	IN
cord-026340-2nf97zvc	321	12	lysosomes	lysosome	NNS
cord-026340-2nf97zvc	321	13	rather	rather	RB
cord-026340-2nf97zvc	321	14	than	than	IN
cord-026340-2nf97zvc	321	15	by	by	IN
cord-026340-2nf97zvc	321	16	affecting	affect	VBG
cord-026340-2nf97zvc	321	17	the	the	DT
cord-026340-2nf97zvc	321	18	acidity	acidity	NN
cord-026340-2nf97zvc	321	19	and/or	and/or	CC
cord-026340-2nf97zvc	321	20	degradative	degradative	JJ
cord-026340-2nf97zvc	321	21	activity	activity	NN
cord-026340-2nf97zvc	321	22	of	of	IN
cord-026340-2nf97zvc	321	23	this	this	DT
cord-026340-2nf97zvc	321	24	organelle	organelle	NN
cord-026340-2nf97zvc	321	25	(	(	-LRB-
cord-026340-2nf97zvc	321	26	Mauthe	Mauthe	NNP
cord-026340-2nf97zvc	321	27	et	et	FW
cord-026340-2nf97zvc	321	28	al	al	NNP
cord-026340-2nf97zvc	321	29	.	.	.
cord-026340-2nf97zvc	321	30	2018	2018	CD
cord-026340-2nf97zvc	321	31	)	)	-RRB-
cord-026340-2nf97zvc	321	32	.	.	.
cord-026340-2nf97zvc	322	1	So	so	RB
cord-026340-2nf97zvc	322	2	,	,	,
cord-026340-2nf97zvc	322	3	the	the	DT
cord-026340-2nf97zvc	322	4	reason	reason	NN
cord-026340-2nf97zvc	322	5	for	for	IN
cord-026340-2nf97zvc	322	6	reduction	reduction	NN
cord-026340-2nf97zvc	322	7	in	in	IN
cord-026340-2nf97zvc	322	8	activity	activity	NN
cord-026340-2nf97zvc	322	9	of	of	IN
cord-026340-2nf97zvc	322	10	lysosome	lysosome	NN
cord-026340-2nf97zvc	322	11	enzyme	enzyme	NN
cord-026340-2nf97zvc	322	12	by	by	IN
cord-026340-2nf97zvc	322	13	CQ	CQ	NNP
cord-026340-2nf97zvc	322	14	as	as	IN
cord-026340-2nf97zvc	322	15	seen	see	VBN
cord-026340-2nf97zvc	322	16	in	in	IN
cord-026340-2nf97zvc	322	17	our	-PRON-	PRP$
cord-026340-2nf97zvc	322	18	pilot	pilot	NN
cord-026340-2nf97zvc	322	19	study	study	NN
cord-026340-2nf97zvc	322	20	requires	require	VBZ
cord-026340-2nf97zvc	322	21	investigation	investigation	NN
cord-026340-2nf97zvc	322	22	.	.	.
cord-026340-2nf97zvc	323	1	We	-PRON-	PRP
cord-026340-2nf97zvc	323	2	are	be	VBP
cord-026340-2nf97zvc	323	3	assuming	assume	VBG
cord-026340-2nf97zvc	323	4	reduction	reduction	NN
cord-026340-2nf97zvc	323	5	in	in	IN
cord-026340-2nf97zvc	323	6	the	the	DT
cord-026340-2nf97zvc	323	7	count	count	NN
cord-026340-2nf97zvc	323	8	and	and	CC
cord-026340-2nf97zvc	323	9	activity	activity	NN
cord-026340-2nf97zvc	323	10	of	of	IN
cord-026340-2nf97zvc	323	11	lysosomes	lysosome	NNS
cord-026340-2nf97zvc	323	12	with	with	IN
cord-026340-2nf97zvc	323	13	CQ	CQ	NNP
cord-026340-2nf97zvc	323	14	exposure	exposure	NN
cord-026340-2nf97zvc	323	15	.	.	.
cord-026340-2nf97zvc	324	1	But	but	CC
cord-026340-2nf97zvc	324	2	whether	whether	IN
cord-026340-2nf97zvc	324	3	BA	BA	NNP
cord-026340-2nf97zvc	324	4	is	be	VBZ
cord-026340-2nf97zvc	324	5	potentiating	potentiate	VBG
cord-026340-2nf97zvc	324	6	the	the	DT
cord-026340-2nf97zvc	324	7	effect	effect	NN
cord-026340-2nf97zvc	324	8	or	or	CC
cord-026340-2nf97zvc	324	9	not	not	RB
cord-026340-2nf97zvc	324	10	requires	require	VBZ
cord-026340-2nf97zvc	324	11	more	more	RBR
cord-026340-2nf97zvc	324	12	sophisticated	sophisticated	JJ
cord-026340-2nf97zvc	324	13	experimentations	experimentation	NNS
cord-026340-2nf97zvc	324	14	which	which	WDT
cord-026340-2nf97zvc	324	15	is	be	VBZ
cord-026340-2nf97zvc	324	16	a	a	DT
cord-026340-2nf97zvc	324	17	futuristic	futuristic	JJ
cord-026340-2nf97zvc	324	18	aspect	aspect	NN
cord-026340-2nf97zvc	324	19	.	.	.
cord-026340-2nf97zvc	325	1	We	-PRON-	PRP
cord-026340-2nf97zvc	325	2	are	be	VBP
cord-026340-2nf97zvc	325	3	hoping	hope	VBG
cord-026340-2nf97zvc	325	4	that	that	IN
cord-026340-2nf97zvc	325	5	if	if	IN
cord-026340-2nf97zvc	325	6	we	-PRON-	PRP
cord-026340-2nf97zvc	325	7	can	can	MD
cord-026340-2nf97zvc	325	8	lower	lower	VB
cord-026340-2nf97zvc	325	9	the	the	DT
cord-026340-2nf97zvc	325	10	dose	dose	NN
cord-026340-2nf97zvc	325	11	of	of	IN
cord-026340-2nf97zvc	325	12	CQ	CQ	NNP
cord-026340-2nf97zvc	325	13	by	by	IN
cord-026340-2nf97zvc	325	14	including	include	VBG
cord-026340-2nf97zvc	325	15	BA	BA	NNP
cord-026340-2nf97zvc	325	16	,	,	,
cord-026340-2nf97zvc	325	17	such	such	JJ
cord-026340-2nf97zvc	325	18	combinational	combinational	JJ
cord-026340-2nf97zvc	325	19	therapy	therapy	NN
cord-026340-2nf97zvc	325	20	Basal	Basal	NNP
cord-026340-2nf97zvc	325	21	C	c	NN
cord-026340-2nf97zvc	325	22	Q	q	NN
cord-026340-2nf97zvc	325	23	C	c	NN
cord-026340-2nf97zvc	325	24	Q+BA	q+ba	NN
cord-026340-2nf97zvc	325	25	BA	BA	NNP
cord-026340-2nf97zvc	325	26	Beta	Beta	NNP
cord-026340-2nf97zvc	325	27	-	-	HYPH
cord-026340-2nf97zvc	325	28	hexosaminidase	hexosaminidase	NN
cord-026340-2nf97zvc	325	29	Activity	Activity	NNP
cord-026340-2nf97zvc	325	30	Fig	Fig	NNP
cord-026340-2nf97zvc	325	31	.	.	.
cord-026340-2nf97zvc	326	1	2	2	LS
cord-026340-2nf97zvc	327	1	The	the	DT
cord-026340-2nf97zvc	327	2	effect	effect	NN
cord-026340-2nf97zvc	327	3	of	of	IN
cord-026340-2nf97zvc	327	4	a	a	DT
cord-026340-2nf97zvc	327	5	combination	combination	NN
cord-026340-2nf97zvc	327	6	of	of	IN
cord-026340-2nf97zvc	327	7	betulinic	betulinic	JJ
cord-026340-2nf97zvc	327	8	acid	acid	NN
cord-026340-2nf97zvc	327	9	and	and	CC
cord-026340-2nf97zvc	327	10	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	327	11	on	on	IN
cord-026340-2nf97zvc	327	12	lysosomal	lysosomal	JJ
cord-026340-2nf97zvc	327	13	function	function	NN
cord-026340-2nf97zvc	327	14	as	as	IN
cord-026340-2nf97zvc	327	15	evidenced	evidence	VBN
cord-026340-2nf97zvc	327	16	by	by	IN
cord-026340-2nf97zvc	327	17	beta	beta	JJ
cord-026340-2nf97zvc	327	18	-	-	HYPH
cord-026340-2nf97zvc	327	19	hexosaminidase	hexosaminidase	NN
cord-026340-2nf97zvc	327	20	activity	activity	NN
cord-026340-2nf97zvc	327	21	in	in	IN
cord-026340-2nf97zvc	327	22	mononuclear	mononuclear	JJ
cord-026340-2nf97zvc	327	23	cells	cell	NNS
cord-026340-2nf97zvc	327	24	.	.	.
cord-026340-2nf97zvc	328	1	Units	unit	NNS
cord-026340-2nf97zvc	328	2	of	of	IN
cord-026340-2nf97zvc	328	3	activity	activity	NN
cord-026340-2nf97zvc	328	4	were	be	VBD
cord-026340-2nf97zvc	328	5	defined	define	VBN
cord-026340-2nf97zvc	328	6	as	as	IN
cord-026340-2nf97zvc	328	7	nanomoles	nanomole	NNS
cord-026340-2nf97zvc	328	8	of	of	IN
cord-026340-2nf97zvc	328	9	substrate	substrate	NN
cord-026340-2nf97zvc	328	10	per	per	IN
cord-026340-2nf97zvc	328	11	hour	hour	NN
cord-026340-2nf97zvc	328	12	per	per	IN
cord-026340-2nf97zvc	328	13	mg	mg	NN
cord-026340-2nf97zvc	328	14	protein	protein	NN
cord-026340-2nf97zvc	328	15	.	.	.
cord-026340-2nf97zvc	329	1	The	the	DT
cord-026340-2nf97zvc	329	2	results	result	NNS
cord-026340-2nf97zvc	329	3	are	be	VBP
cord-026340-2nf97zvc	329	4	a	a	DT
cord-026340-2nf97zvc	329	5	mean	mean	NN
cord-026340-2nf97zvc	329	6	of	of	IN
cord-026340-2nf97zvc	329	7	3	3	CD
cord-026340-2nf97zvc	329	8	experiments	experiment	NNS
cord-026340-2nf97zvc	329	9	where	where	WRB
cord-026340-2nf97zvc	329	10	each	each	DT
cord-026340-2nf97zvc	329	11	experiment	experiment	NN
cord-026340-2nf97zvc	329	12	was	be	VBD
cord-026340-2nf97zvc	329	13	conducted	conduct	VBN
cord-026340-2nf97zvc	329	14	in	in	IN
cord-026340-2nf97zvc	329	15	duplicate	duplicate	NN
cord-026340-2nf97zvc	329	16	.	.	.
cord-026340-2nf97zvc	330	1	Statistical	statistical	JJ
cord-026340-2nf97zvc	330	2	analysis	analysis	NN
cord-026340-2nf97zvc	330	3	was	be	VBD
cord-026340-2nf97zvc	330	4	conducted	conduct	VBN
cord-026340-2nf97zvc	330	5	by	by	IN
cord-026340-2nf97zvc	330	6	ANOVA	ANOVA	NNP
cord-026340-2nf97zvc	330	7	followed	follow	VBN
cord-026340-2nf97zvc	330	8	by	by	IN
cord-026340-2nf97zvc	330	9	Duncan	Duncan	NNP
cord-026340-2nf97zvc	330	10	test	test	NN
cord-026340-2nf97zvc	330	11	using	use	VBG
cord-026340-2nf97zvc	330	12	SPSS	SPSS	NNP
cord-026340-2nf97zvc	330	13	software	software	NN
cord-026340-2nf97zvc	330	14	can	can	MD
cord-026340-2nf97zvc	330	15	be	be	VB
cord-026340-2nf97zvc	330	16	considered	consider	VBN
cord-026340-2nf97zvc	330	17	for	for	IN
cord-026340-2nf97zvc	330	18	improving	improve	VBG
cord-026340-2nf97zvc	330	19	efficacy	efficacy	NN
cord-026340-2nf97zvc	330	20	of	of	IN
cord-026340-2nf97zvc	330	21	treatment	treatment	NN
cord-026340-2nf97zvc	330	22	in	in	IN
cord-026340-2nf97zvc	330	23	conditions	condition	NNS
cord-026340-2nf97zvc	330	24	of	of	IN
cord-026340-2nf97zvc	330	25	pathogen	pathogen	NN
cord-026340-2nf97zvc	330	26	overload	overload	NN
cord-026340-2nf97zvc	330	27	.	.	.
cord-026340-2nf97zvc	331	1	CQ	CQ	NNP
cord-026340-2nf97zvc	331	2	has	have	VBZ
cord-026340-2nf97zvc	331	3	been	be	VBN
cord-026340-2nf97zvc	331	4	in	in	IN
cord-026340-2nf97zvc	331	5	pharmaceutical	pharmaceutical	JJ
cord-026340-2nf97zvc	331	6	industry	industry	NN
cord-026340-2nf97zvc	331	7	for	for	IN
cord-026340-2nf97zvc	331	8	50	50	CD
cord-026340-2nf97zvc	331	9	years	year	NNS
cord-026340-2nf97zvc	331	10	now	now	RB
cord-026340-2nf97zvc	331	11	.	.	.
cord-026340-2nf97zvc	332	1	It	-PRON-	PRP
cord-026340-2nf97zvc	332	2	has	have	VBZ
cord-026340-2nf97zvc	332	3	low	low	JJ
cord-026340-2nf97zvc	332	4	cost	cost	NN
cord-026340-2nf97zvc	332	5	and	and	CC
cord-026340-2nf97zvc	332	6	is	be	VBZ
cord-026340-2nf97zvc	332	7	reasonably	reasonably	RB
cord-026340-2nf97zvc	332	8	safe	safe	JJ
cord-026340-2nf97zvc	332	9	to	to	TO
cord-026340-2nf97zvc	332	10	use	use	VB
cord-026340-2nf97zvc	332	11	and	and	CC
cord-026340-2nf97zvc	332	12	widely	widely	RB
cord-026340-2nf97zvc	332	13	available	available	JJ
cord-026340-2nf97zvc	332	14	in	in	IN
cord-026340-2nf97zvc	332	15	countries	country	NNS
cord-026340-2nf97zvc	332	16	where	where	WRB
cord-026340-2nf97zvc	332	17	malaria	malaria	NN
cord-026340-2nf97zvc	332	18	is	be	VBZ
cord-026340-2nf97zvc	332	19	endemic	endemic	JJ
cord-026340-2nf97zvc	332	20	,	,	,
cord-026340-2nf97zvc	332	21	but	but	CC
cord-026340-2nf97zvc	332	22	CQ	CQ	NNP
cord-026340-2nf97zvc	332	23	usage	usage	NN
cord-026340-2nf97zvc	332	24	warrants	warrant	NNS
cord-026340-2nf97zvc	332	25	frequent	frequent	JJ
cord-026340-2nf97zvc	332	26	monitoring	monitoring	NN
cord-026340-2nf97zvc	332	27	of	of	IN
cord-026340-2nf97zvc	332	28	physiological	physiological	JJ
cord-026340-2nf97zvc	332	29	parameters	parameter	NNS
cord-026340-2nf97zvc	332	30	to	to	TO
cord-026340-2nf97zvc	332	31	avoid	avoid	VB
cord-026340-2nf97zvc	332	32	any	any	DT
cord-026340-2nf97zvc	332	33	adverse	adverse	JJ
cord-026340-2nf97zvc	332	34	effects	effect	NNS
cord-026340-2nf97zvc	332	35	.	.	.
cord-026340-2nf97zvc	333	1	CQ	CQ	NNP
cord-026340-2nf97zvc	333	2	has	have	VBZ
cord-026340-2nf97zvc	333	3	distinct	distinct	JJ
cord-026340-2nf97zvc	333	4	ways	way	NNS
cord-026340-2nf97zvc	333	5	of	of	IN
cord-026340-2nf97zvc	333	6	attacking	attack	VBG
cord-026340-2nf97zvc	333	7	a	a	DT
cord-026340-2nf97zvc	333	8	virus	virus	NN
cord-026340-2nf97zvc	333	9	.	.	.
cord-026340-2nf97zvc	334	1	CQ	CQ	NNP
cord-026340-2nf97zvc	334	2	interferes	interfere	VBZ
cord-026340-2nf97zvc	334	3	with	with	IN
cord-026340-2nf97zvc	334	4	the	the	DT
cord-026340-2nf97zvc	334	5	glycosylation	glycosylation	NN
cord-026340-2nf97zvc	334	6	of	of	IN
cord-026340-2nf97zvc	334	7	cellular	cellular	JJ
cord-026340-2nf97zvc	334	8	receptor	receptor	NN
cord-026340-2nf97zvc	334	9	of	of	IN
cord-026340-2nf97zvc	334	10	SARS	SARS	NNP
cord-026340-2nf97zvc	334	11	-	-	HYPH
cord-026340-2nf97zvc	334	12	CoV	CoV	NNP
cord-026340-2nf97zvc	334	13	to	to	TO
cord-026340-2nf97zvc	334	14	block	block	VB
cord-026340-2nf97zvc	334	15	viral	viral	JJ
cord-026340-2nf97zvc	334	16	infection	infection	NN
cord-026340-2nf97zvc	334	17	.	.	.
cord-026340-2nf97zvc	335	1	CQ	CQ	NNP
cord-026340-2nf97zvc	335	2	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	335	3	the	the	DT
cord-026340-2nf97zvc	335	4	quinone	quinone	NN
cord-026340-2nf97zvc	335	5	reductase-2	reductase-2	NNP
cord-026340-2nf97zvc	335	6	,	,	,
cord-026340-2nf97zvc	335	7	which	which	WDT
cord-026340-2nf97zvc	335	8	is	be	VBZ
cord-026340-2nf97zvc	335	9	involved	involve	VBN
cord-026340-2nf97zvc	335	10	in	in	IN
cord-026340-2nf97zvc	335	11	sialic	sialic	JJ
cord-026340-2nf97zvc	335	12	acid	acid	NN
cord-026340-2nf97zvc	335	13	biosynthesis	biosynthesis	NN
cord-026340-2nf97zvc	335	14	required	require	VBN
cord-026340-2nf97zvc	335	15	for	for	IN
cord-026340-2nf97zvc	335	16	ligand	ligand	NN
cord-026340-2nf97zvc	335	17	recognition	recognition	NN
cord-026340-2nf97zvc	335	18	.	.	.
cord-026340-2nf97zvc	336	1	CQ	CQ	NNP
cord-026340-2nf97zvc	336	2	changes	change	VBZ
cord-026340-2nf97zvc	336	3	the	the	DT
cord-026340-2nf97zvc	336	4	pH	ph	NN
cord-026340-2nf97zvc	336	5	of	of	IN
cord-026340-2nf97zvc	336	6	lysosomes	lysosome	NNS
cord-026340-2nf97zvc	336	7	and	and	CC
cord-026340-2nf97zvc	336	8	likely	likely	RB
cord-026340-2nf97zvc	336	9	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	336	10	cathepsins	cathepsin	NNS
cord-026340-2nf97zvc	336	11	that	that	WDT
cord-026340-2nf97zvc	336	12	lead	lead	VBP
cord-026340-2nf97zvc	336	13	to	to	IN
cord-026340-2nf97zvc	336	14	the	the	DT
cord-026340-2nf97zvc	336	15	formation	formation	NN
cord-026340-2nf97zvc	336	16	of	of	IN
cord-026340-2nf97zvc	336	17	the	the	DT
cord-026340-2nf97zvc	336	18	autophagosome	autophagosome	NN
cord-026340-2nf97zvc	336	19	which	which	WDT
cord-026340-2nf97zvc	336	20	cleaves	cleave	VBZ
cord-026340-2nf97zvc	336	21	SARS	SARS	NNP
cord-026340-2nf97zvc	336	22	-	-	HYPH
cord-026340-2nf97zvc	336	23	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	336	24	spike	spike	NN
cord-026340-2nf97zvc	336	25	protein	protein	NN
cord-026340-2nf97zvc	336	26	.	.	.
cord-026340-2nf97zvc	337	1	The	the	DT
cord-026340-2nf97zvc	337	2	potency	potency	NN
cord-026340-2nf97zvc	337	3	of	of	IN
cord-026340-2nf97zvc	337	4	CQ	CQ	NNP
cord-026340-2nf97zvc	337	5	can	can	MD
cord-026340-2nf97zvc	337	6	be	be	VB
cord-026340-2nf97zvc	337	7	increased	increase	VBN
cord-026340-2nf97zvc	337	8	when	when	WRB
cord-026340-2nf97zvc	337	9	used	use	VBN
cord-026340-2nf97zvc	337	10	with	with	IN
cord-026340-2nf97zvc	337	11	an	an	DT
cord-026340-2nf97zvc	337	12	anti	anti	JJ
cord-026340-2nf97zvc	337	13	-	-	JJ
cord-026340-2nf97zvc	337	14	viral	viral	JJ
cord-026340-2nf97zvc	337	15	agent	agent	NN
cord-026340-2nf97zvc	337	16	.	.	.
cord-026340-2nf97zvc	338	1	The	the	DT
cord-026340-2nf97zvc	338	2	Government	Government	NNP
cord-026340-2nf97zvc	338	3	of	of	IN
cord-026340-2nf97zvc	338	4	India	India	NNP
cord-026340-2nf97zvc	338	5	has	have	VBZ
cord-026340-2nf97zvc	338	6	put	put	VBN
cord-026340-2nf97zvc	338	7	up	up	RP
cord-026340-2nf97zvc	338	8	a	a	DT
cord-026340-2nf97zvc	338	9	platform	platform	NN
cord-026340-2nf97zvc	338	10	for	for	IN
cord-026340-2nf97zvc	338	11	identifying	identify	VBG
cord-026340-2nf97zvc	338	12	the	the	DT
cord-026340-2nf97zvc	338	13	use	use	NN
cord-026340-2nf97zvc	338	14	of	of	IN
cord-026340-2nf97zvc	338	15	botanicals	botanical	NNS
cord-026340-2nf97zvc	338	16	to	to	TO
cord-026340-2nf97zvc	338	17	treat	treat	VB
cord-026340-2nf97zvc	338	18	disorders	disorder	NNS
cord-026340-2nf97zvc	338	19	.	.	.
cord-026340-2nf97zvc	339	1	In	in	IN
cord-026340-2nf97zvc	339	2	that	that	DT
cord-026340-2nf97zvc	339	3	context	context	NN
cord-026340-2nf97zvc	339	4	,	,	,
cord-026340-2nf97zvc	339	5	the	the	DT
cord-026340-2nf97zvc	339	6	effect	effect	NN
cord-026340-2nf97zvc	339	7	of	of	IN
cord-026340-2nf97zvc	339	8	a	a	DT
cord-026340-2nf97zvc	339	9	botanical	botanical	JJ
cord-026340-2nf97zvc	339	10	like	like	IN
cord-026340-2nf97zvc	339	11	betulinic	betulinic	JJ
cord-026340-2nf97zvc	339	12	acid	acid	NN
cord-026340-2nf97zvc	339	13	was	be	VBD
cord-026340-2nf97zvc	339	14	tested	test	VBN
cord-026340-2nf97zvc	339	15	.	.	.
cord-026340-2nf97zvc	340	1	This	this	DT
cord-026340-2nf97zvc	340	2	botanical	botanical	NN
cord-026340-2nf97zvc	340	3	has	have	VBZ
cord-026340-2nf97zvc	340	4	reported	report	VBN
cord-026340-2nf97zvc	340	5	that	that	IN
cord-026340-2nf97zvc	340	6	anti	anti	JJ
cord-026340-2nf97zvc	340	7	-	-	JJ
cord-026340-2nf97zvc	340	8	viral	viral	JJ
cord-026340-2nf97zvc	340	9	effect	effect	NN
cord-026340-2nf97zvc	340	10	may	may	MD
cord-026340-2nf97zvc	340	11	aid	aid	VB
cord-026340-2nf97zvc	340	12	to	to	TO
cord-026340-2nf97zvc	340	13	reduce	reduce	VB
cord-026340-2nf97zvc	340	14	the	the	DT
cord-026340-2nf97zvc	340	15	dose	dose	NN
cord-026340-2nf97zvc	340	16	of	of	IN
cord-026340-2nf97zvc	340	17	CQ	CQ	NNP
cord-026340-2nf97zvc	340	18	for	for	IN
cord-026340-2nf97zvc	340	19	prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	340	20	or	or	CC
cord-026340-2nf97zvc	340	21	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	340	22	regimen	regimen	NN
cord-026340-2nf97zvc	340	23	.	.	.
cord-026340-2nf97zvc	341	1	Pre	pre	JJ
cord-026340-2nf97zvc	341	2	-	-	JJ
cord-026340-2nf97zvc	341	3	clinical	clinical	JJ
cord-026340-2nf97zvc	341	4	and	and	CC
cord-026340-2nf97zvc	341	5	clinical	clinical	JJ
cord-026340-2nf97zvc	341	6	studies	study	NNS
cord-026340-2nf97zvc	341	7	are	be	VBP
cord-026340-2nf97zvc	341	8	required	require	VBN
cord-026340-2nf97zvc	341	9	to	to	TO
cord-026340-2nf97zvc	341	10	confirm	confirm	VB
cord-026340-2nf97zvc	341	11	this	this	DT
cord-026340-2nf97zvc	341	12	.	.	.
cord-026340-2nf97zvc	342	1	Recent	recent	JJ
cord-026340-2nf97zvc	342	2	progress	progress	NN
cord-026340-2nf97zvc	342	3	and	and	CC
cord-026340-2nf97zvc	342	4	challenges	challenge	NNS
cord-026340-2nf97zvc	342	5	in	in	IN
cord-026340-2nf97zvc	342	6	drug	drug	NN
cord-026340-2nf97zvc	342	7	development	development	NN
cord-026340-2nf97zvc	342	8	against	against	IN
cord-026340-2nf97zvc	342	9	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	342	10	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	342	11	(	(	-LRB-
cord-026340-2nf97zvc	342	12	SARS	SARS	NNP
cord-026340-2nf97zvc	342	13	-	-	HYPH
cord-026340-2nf97zvc	342	14	CoV-2)-an	CoV-2)-an	NNP
cord-026340-2nf97zvc	342	15	update	update	NN
cord-026340-2nf97zvc	342	16	on	on	IN
cord-026340-2nf97zvc	342	17	the	the	DT
cord-026340-2nf97zvc	342	18	status	status	NN
cord-026340-2nf97zvc	342	19	Surviving	survive	VBG
cord-026340-2nf97zvc	342	20	sepsis	sepsis	NN
cord-026340-2nf97zvc	342	21	campaign	campaign	NN
cord-026340-2nf97zvc	342	22	:	:	:
cord-026340-2nf97zvc	342	23	guidelines	guideline	NNS
cord-026340-2nf97zvc	342	24	on	on	IN
cord-026340-2nf97zvc	342	25	the	the	DT
cord-026340-2nf97zvc	342	26	management	management	NN
cord-026340-2nf97zvc	342	27	of	of	IN
cord-026340-2nf97zvc	342	28	critically	critically	RB
cord-026340-2nf97zvc	342	29	ill	ill	JJ
cord-026340-2nf97zvc	342	30	adults	adult	NNS
cord-026340-2nf97zvc	342	31	with	with	IN
cord-026340-2nf97zvc	342	32	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	342	33	disease	disease	NN
cord-026340-2nf97zvc	342	34	2019	2019	CD
cord-026340-2nf97zvc	343	1	(	(	-LRB-
cord-026340-2nf97zvc	343	2	COVID-19	covid-19	VB
cord-026340-2nf97zvc	343	3	)	)	-RRB-
cord-026340-2nf97zvc	343	4	The	the	DT
cord-026340-2nf97zvc	343	5	proximal	proximal	JJ
cord-026340-2nf97zvc	343	6	origin	origin	NN
cord-026340-2nf97zvc	343	7	of	of	IN
cord-026340-2nf97zvc	343	8	SARS	SARS	NNP
cord-026340-2nf97zvc	343	9	-	-	HYPH
cord-026340-2nf97zvc	343	10	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	343	11	Interim	interim	JJ
cord-026340-2nf97zvc	343	12	clinical	clinical	JJ
cord-026340-2nf97zvc	343	13	guidelines	guideline	NNS
cord-026340-2nf97zvc	343	14	for	for	IN
cord-026340-2nf97zvc	343	15	patients	patient	NNS
cord-026340-2nf97zvc	343	16	suspected	suspect	VBN
cord-026340-2nf97zvc	343	17	of	of	IN
cord-026340-2nf97zvc	343	18	/	/	SYM
cord-026340-2nf97zvc	343	19	confirmed	confirm	VBD
cord-026340-2nf97zvc	343	20	with	with	IN
cord-026340-2nf97zvc	343	21	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	343	22	infection	infection	NN
cord-026340-2nf97zvc	343	23	Mechanisms	Mechanisms	NNPS
cord-026340-2nf97zvc	343	24	of	of	IN
cord-026340-2nf97zvc	343	25	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	343	26	cell	cell	NN
cord-026340-2nf97zvc	343	27	entry	entry	NN
cord-026340-2nf97zvc	343	28	mediated	mediate	VBN
cord-026340-2nf97zvc	343	29	by	by	IN
cord-026340-2nf97zvc	343	30	the	the	DT
cord-026340-2nf97zvc	343	31	viral	viral	JJ
cord-026340-2nf97zvc	343	32	spike	spike	NN
cord-026340-2nf97zvc	343	33	protein	protein	NN
cord-026340-2nf97zvc	343	34	Examination	examination	NN
cord-026340-2nf97zvc	343	35	of	of	IN
cord-026340-2nf97zvc	343	36	potential	potential	JJ
cord-026340-2nf97zvc	343	37	inhibitors	inhibitor	NNS
cord-026340-2nf97zvc	343	38	of	of	IN
cord-026340-2nf97zvc	343	39	A	a	DT
cord-026340-2nf97zvc	343	40	virus	virus	NN
cord-026340-2nf97zvc	343	41	uncoating	uncoate	VBG
cord-026340-2nf97zvc	343	42	Bats	bat	NNS
cord-026340-2nf97zvc	343	43	:	:	:
cord-026340-2nf97zvc	343	44	important	important	JJ
cord-026340-2nf97zvc	343	45	reservoir	reservoir	NN
cord-026340-2nf97zvc	343	46	hosts	host	NNS
cord-026340-2nf97zvc	343	47	of	of	IN
cord-026340-2nf97zvc	343	48	emerging	emerge	VBG
cord-026340-2nf97zvc	343	49	viruses	virus	NNS
cord-026340-2nf97zvc	343	50	Effects	effect	NNS
cord-026340-2nf97zvc	343	51	of	of	IN
cord-026340-2nf97zvc	343	52	lysosomotropic	lysosomotropic	JJ
cord-026340-2nf97zvc	343	53	weak	weak	JJ
cord-026340-2nf97zvc	343	54	bases	basis	NNS
cord-026340-2nf97zvc	343	55	on	on	IN
cord-026340-2nf97zvc	343	56	infection	infection	NN
cord-026340-2nf97zvc	343	57	of	of	IN
cord-026340-2nf97zvc	343	58	BHK-21	BHK-21	NNP
cord-026340-2nf97zvc	343	59	cells	cell	NNS
cord-026340-2nf97zvc	343	60	by	by	IN
cord-026340-2nf97zvc	343	61	Sindbis	Sindbis	NNP
cord-026340-2nf97zvc	343	62	virus	virus	NN
cord-026340-2nf97zvc	343	63	mnote	mnote	NNP
cord-026340-2nf97zvc	343	64	s	s	NNP
cord-026340-2nf97zvc	343	65	/	/	SYM
cord-026340-2nf97zvc	343	66	proto	proto	JJ
cord-026340-2nf97zvc	343	67	col	col	NN
cord-026340-2nf97zvc	343	68	-	-	HYPH
cord-026340-2nf97zvc	343	69	for	for	IN
cord-026340-2nf97zvc	343	70	-	-	HYPH
cord-026340-2nf97zvc	343	71	treat	treat	NN
cord-026340-2nf97zvc	343	72	ment	ment	NN
cord-026340-2nf97zvc	343	73	-	-	HYPH
cord-026340-2nf97zvc	343	74	of	of	IN
cord-026340-2nf97zvc	343	75	-	-	HYPH
cord-026340-2nf97zvc	343	76	confi	confi	NN
cord-026340-2nf97zvc	343	77	rmedc	rmedc	NNP
cord-026340-2nf97zvc	343	78	ovid-19	ovid-19	NNP
cord-026340-2nf97zvc	343	79	-	-	HYPH
cord-026340-2nf97zvc	343	80	5e5e2	5e5e2	CD
cord-026340-2nf97zvc	343	81	781e8	781e8	VBN
cord-026340-2nf97zvc	343	82	6c5d0	6c5d0	CD
cord-026340-2nf97zvc	343	83	001f7	001f7	CD
cord-026340-2nf97zvc	343	84	7303	7303	CD
cord-026340-2nf97zvc	343	85	Severe	severe	JJ
cord-026340-2nf97zvc	343	86	acute	acute	JJ
cord-026340-2nf97zvc	343	87	respiratory	respiratory	JJ
cord-026340-2nf97zvc	343	88	syndrome	syndrome	NN
cord-026340-2nf97zvc	343	89	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	343	90	as	as	IN
cord-026340-2nf97zvc	343	91	an	an	DT
cord-026340-2nf97zvc	343	92	agent	agent	NN
cord-026340-2nf97zvc	343	93	of	of	IN
cord-026340-2nf97zvc	343	94	emerging	emerge	VBG
cord-026340-2nf97zvc	343	95	and	and	CC
cord-026340-2nf97zvc	343	96	reemerging	reemerge	VBG
cord-026340-2nf97zvc	343	97	infection	infection	NN
cord-026340-2nf97zvc	343	98	Antistress	Antistress	NNP
cord-026340-2nf97zvc	343	99	effects	effect	NNS
cord-026340-2nf97zvc	343	100	of	of	IN
cord-026340-2nf97zvc	343	101	bacosides	bacoside	NNS
cord-026340-2nf97zvc	343	102	of	of	IN
cord-026340-2nf97zvc	343	103	Bacopa	Bacopa	NNP
cord-026340-2nf97zvc	343	104	monnieri	monnieri	NN
cord-026340-2nf97zvc	343	105	:	:	:
cord-026340-2nf97zvc	343	106	modulation	modulation	NN
cord-026340-2nf97zvc	343	107	of	of	IN
cord-026340-2nf97zvc	343	108	Hsp70	Hsp70	NNP
cord-026340-2nf97zvc	343	109	expression	expression	NN
cord-026340-2nf97zvc	343	110	,	,	,
cord-026340-2nf97zvc	343	111	superoxide	superoxide	NN
cord-026340-2nf97zvc	343	112	dismutase	dismutase	NN
cord-026340-2nf97zvc	343	113	and	and	CC
cord-026340-2nf97zvc	343	114	cytochrome	cytochrome	NN
cord-026340-2nf97zvc	343	115	P450	p450	JJ
cord-026340-2nf97zvc	343	116	activity	activity	NN
cord-026340-2nf97zvc	343	117	in	in	IN
cord-026340-2nf97zvc	343	118	rat	rat	NN
cord-026340-2nf97zvc	343	119	brain	brain	NN
cord-026340-2nf97zvc	343	120	Pitfalls	pitfall	NNS
cord-026340-2nf97zvc	343	121	in	in	IN
cord-026340-2nf97zvc	343	122	a	a	DT
cord-026340-2nf97zvc	343	123	discovery	discovery	NN
cord-026340-2nf97zvc	343	124	:	:	:
cord-026340-2nf97zvc	343	125	the	the	DT
cord-026340-2nf97zvc	343	126	chronicle	chronicle	NN
cord-026340-2nf97zvc	343	127	of	of	IN
cord-026340-2nf97zvc	343	128	chloroquine	chloroquine	NNP
cord-026340-2nf97zvc	343	129	Chlorpquine	Chlorpquine	NNP
cord-026340-2nf97zvc	343	130	in	in	IN
cord-026340-2nf97zvc	343	131	amebiasis	amebiasis	NNP
cord-026340-2nf97zvc	343	132	Induction	Induction	NNP
cord-026340-2nf97zvc	343	133	of	of	IN
cord-026340-2nf97zvc	343	134	pro	pro	JJ
cord-026340-2nf97zvc	343	135	-	-	JJ
cord-026340-2nf97zvc	343	136	inflammatory	inflammatory	JJ
cord-026340-2nf97zvc	343	137	cytokines	cytokine	NNS
cord-026340-2nf97zvc	343	138	(	(	-LRB-
cord-026340-2nf97zvc	343	139	IL-1	IL-1	NNP
cord-026340-2nf97zvc	343	140	and	and	CC
cord-026340-2nf97zvc	343	141	IL-6	IL-6	NNP
cord-026340-2nf97zvc	343	142	)	)	-RRB-
cord-026340-2nf97zvc	343	143	and	and	CC
cord-026340-2nf97zvc	343	144	lung	lung	NN
cord-026340-2nf97zvc	343	145	inflammation	inflammation	NN
cord-026340-2nf97zvc	343	146	by	by	IN
cord-026340-2nf97zvc	343	147	coronavirus-19	coronavirus-19	NNP
cord-026340-2nf97zvc	344	1	(	(	-LRB-
cord-026340-2nf97zvc	344	2	COVI-19	covi-19	JJ
cord-026340-2nf97zvc	344	3	or	or	CC
cord-026340-2nf97zvc	344	4	SARS	SARS	NNP
cord-026340-2nf97zvc	344	5	-	-	HYPH
cord-026340-2nf97zvc	344	6	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	344	7	)	)	-RRB-
cord-026340-2nf97zvc	344	8	:	:	:
cord-026340-2nf97zvc	344	9	anti	anti	JJ
cord-026340-2nf97zvc	344	10	-	-	JJ
cord-026340-2nf97zvc	344	11	inflammatory	inflammatory	JJ
cord-026340-2nf97zvc	344	12	strategies	strategy	NNS
cord-026340-2nf97zvc	344	13	Antimalarial	Antimalarial	NNP
cord-026340-2nf97zvc	344	14	activity	activity	NN
cord-026340-2nf97zvc	344	15	of	of	IN
cord-026340-2nf97zvc	344	16	betulinic	betulinic	JJ
cord-026340-2nf97zvc	344	17	acid	acid	NN
cord-026340-2nf97zvc	344	18	and	and	CC
cord-026340-2nf97zvc	344	19	derivatives	derivative	NNS
cord-026340-2nf97zvc	344	20	in	in	IN
cord-026340-2nf97zvc	344	21	vitro	vitro	FW
cord-026340-2nf97zvc	344	22	against	against	IN
cord-026340-2nf97zvc	344	23	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	344	24	falciparum	falciparum	NNS
cord-026340-2nf97zvc	344	25	and	and	CC
cord-026340-2nf97zvc	344	26	in	in	IN
cord-026340-2nf97zvc	344	27	vivo	vivo	NN
cord-026340-2nf97zvc	344	28	in	in	IN
cord-026340-2nf97zvc	344	29	P.	P.	NNP
cord-026340-2nf97zvc	344	30	bergheiinfected	bergheiinfecte	VBD
cord-026340-2nf97zvc	344	31	mice	mouse	NNS
cord-026340-2nf97zvc	345	1	New	new	JJ
cord-026340-2nf97zvc	345	2	insights	insight	NNS
cord-026340-2nf97zvc	345	3	on	on	IN
cord-026340-2nf97zvc	345	4	the	the	DT
cord-026340-2nf97zvc	345	5	antiviral	antiviral	JJ
cord-026340-2nf97zvc	345	6	effects	effect	NNS
cord-026340-2nf97zvc	345	7	of	of	IN
cord-026340-2nf97zvc	345	8	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	345	9	against	against	IN
cord-026340-2nf97zvc	345	10	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	346	1	:	:	:
cord-026340-2nf97zvc	346	2	what	what	WP
cord-026340-2nf97zvc	346	3	to	to	TO
cord-026340-2nf97zvc	346	4	expect	expect	VB
cord-026340-2nf97zvc	346	5	for	for	IN
cord-026340-2nf97zvc	346	6	COVID-19	covid-19	NN
cord-026340-2nf97zvc	346	7	?	?	.
cord-026340-2nf97zvc	347	1	Discovering	discover	VBG
cord-026340-2nf97zvc	347	2	drugs	drug	NNS
cord-026340-2nf97zvc	347	3	to	to	TO
cord-026340-2nf97zvc	347	4	treat	treat	VB
cord-026340-2nf97zvc	347	5	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	347	6	disease	disease	NN
cord-026340-2nf97zvc	347	7	2019	2019	CD
cord-026340-2nf97zvc	347	8	(	(	-LRB-
cord-026340-2nf97zvc	347	9	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	347	10	)	)	-RRB-
cord-026340-2nf97zvc	347	11	Mount	Mount	NNP
cord-026340-2nf97zvc	347	12	Sinai	Sinai	NNP
cord-026340-2nf97zvc	347	13	health	health	NN
cord-026340-2nf97zvc	347	14	system	system	NN
cord-026340-2nf97zvc	347	15	treatment	treatment	NN
cord-026340-2nf97zvc	347	16	guidelines	guideline	NNS
cord-026340-2nf97zvc	347	17	for	for	IN
cord-026340-2nf97zvc	347	18	SARS	SARS	NNP
cord-026340-2nf97zvc	347	19	-	-	HYPH
cord-026340-2nf97zvc	347	20	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	347	21	infection	infection	NN
cord-026340-2nf97zvc	347	22	(	(	-LRB-
cord-026340-2nf97zvc	347	23	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	347	24	Novel	Novel	NNP
cord-026340-2nf97zvc	347	25	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	347	26	and	and	CC
cord-026340-2nf97zvc	347	27	severe	severe	JJ
cord-026340-2nf97zvc	347	28	acute	acute	JJ
cord-026340-2nf97zvc	347	29	respiratory	respiratory	JJ
cord-026340-2nf97zvc	347	30	syndrome	syndrome	NN
cord-026340-2nf97zvc	347	31	Breakthrough	breakthrough	NN
cord-026340-2nf97zvc	347	32	:	:	:
cord-026340-2nf97zvc	347	33	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	347	34	phosphate	phosphate	NN
cord-026340-2nf97zvc	347	35	has	have	VBZ
cord-026340-2nf97zvc	347	36	shown	show	VBN
cord-026340-2nf97zvc	347	37	apparent	apparent	JJ
cord-026340-2nf97zvc	347	38	efficacy	efficacy	NN
cord-026340-2nf97zvc	347	39	in	in	IN
cord-026340-2nf97zvc	347	40	treatment	treatment	NN
cord-026340-2nf97zvc	347	41	of	of	IN
cord-026340-2nf97zvc	347	42	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	347	43	associated	associated	JJ
cord-026340-2nf97zvc	347	44	pneumonia	pneumonia	NN
cord-026340-2nf97zvc	347	45	in	in	IN
cord-026340-2nf97zvc	347	46	clinical	clinical	JJ
cord-026340-2nf97zvc	347	47	studies	study	NNS
cord-026340-2nf97zvc	347	48	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-026340-2nf97zvc	347	49	and	and	CC
cord-026340-2nf97zvc	347	50	azithromycin	azithromycin	NNP
cord-026340-2nf97zvc	347	51	as	as	IN
cord-026340-2nf97zvc	347	52	a	a	DT
cord-026340-2nf97zvc	347	53	treatment	treatment	NN
cord-026340-2nf97zvc	347	54	of	of	IN
cord-026340-2nf97zvc	347	55	COVID-19	covid-19	NN
cord-026340-2nf97zvc	347	56	:	:	:
cord-026340-2nf97zvc	347	57	results	result	NNS
cord-026340-2nf97zvc	347	58	of	of	IN
cord-026340-2nf97zvc	347	59	an	an	DT
cord-026340-2nf97zvc	347	60	open	open	JJ
cord-026340-2nf97zvc	347	61	-	-	HYPH
cord-026340-2nf97zvc	347	62	label	label	NN
cord-026340-2nf97zvc	347	63	non	non	JJ
cord-026340-2nf97zvc	347	64	-	-	JJ
cord-026340-2nf97zvc	347	65	randomized	randomized	JJ
cord-026340-2nf97zvc	347	66	clinical	clinical	JJ
cord-026340-2nf97zvc	347	67	trial	trial	NN
cord-026340-2nf97zvc	347	68	Tissue	tissue	NN
cord-026340-2nf97zvc	347	69	distribution	distribution	NN
cord-026340-2nf97zvc	347	70	of	of	IN
cord-026340-2nf97zvc	347	71	ACE2	ACE2	NNP
cord-026340-2nf97zvc	347	72	protein	protein	NN
cord-026340-2nf97zvc	347	73	,	,	,
cord-026340-2nf97zvc	347	74	the	the	DT
cord-026340-2nf97zvc	347	75	functional	functional	JJ
cord-026340-2nf97zvc	347	76	receptor	receptor	NN
cord-026340-2nf97zvc	347	77	for	for	IN
cord-026340-2nf97zvc	347	78	SARS	SARS	NNP
cord-026340-2nf97zvc	347	79	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	347	80	.	.	.
cord-026340-2nf97zvc	348	1	A	a	DT
cord-026340-2nf97zvc	348	2	first	first	JJ
cord-026340-2nf97zvc	348	3	step	step	NN
cord-026340-2nf97zvc	348	4	in	in	IN
cord-026340-2nf97zvc	348	5	understanding	understand	VBG
cord-026340-2nf97zvc	348	6	SARS	SARS	NNP
cord-026340-2nf97zvc	348	7	pathogenesis	pathogenesis	NN
cord-026340-2nf97zvc	348	8	Caution	caution	NN
cord-026340-2nf97zvc	348	9	and	and	CC
cord-026340-2nf97zvc	348	10	clarity	clarity	NN
cord-026340-2nf97zvc	348	11	required	require	VBN
cord-026340-2nf97zvc	348	12	in	in	IN
cord-026340-2nf97zvc	348	13	the	the	DT
cord-026340-2nf97zvc	348	14	use	use	NN
cord-026340-2nf97zvc	348	15	of	of	IN
cord-026340-2nf97zvc	348	16	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	348	17	for	for	IN
cord-026340-2nf97zvc	348	18	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	348	19	.	.	.
cord-026340-2nf97zvc	349	1	www.thela	www.thela	NNP
cord-026340-2nf97zvc	349	2	ncet.com/rheum	ncet.com/rheum	NNP
cord-026340-2nf97zvc	349	3	atolo	atolo	NN
cord-026340-2nf97zvc	349	4	gy	gy	NNP
cord-026340-2nf97zvc	349	5	Advisory	Advisory	NNP
cord-026340-2nf97zvc	349	6	on	on	IN
cord-026340-2nf97zvc	349	7	use	use	NN
cord-026340-2nf97zvc	349	8	of	of	IN
cord-026340-2nf97zvc	349	9	hydroxy	hydroxy	NN
cord-026340-2nf97zvc	349	10	-	-	HYPH
cord-026340-2nf97zvc	349	11	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	349	12	as	as	IN
cord-026340-2nf97zvc	349	13	prophylaxis	prophylaxis	NN
cord-026340-2nf97zvc	349	14	for	for	IN
cord-026340-2nf97zvc	349	15	SARS	SARS	NNP
cord-026340-2nf97zvc	349	16	-	-	HYPH
cord-026340-2nf97zvc	349	17	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	349	18	infection	infection	NN
cord-026340-2nf97zvc	349	19	Expert	expert	NN
cord-026340-2nf97zvc	349	20	consensus	consensus	NN
cord-026340-2nf97zvc	349	21	on	on	IN
cord-026340-2nf97zvc	349	22	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	349	23	phosphate	phosphate	NN
cord-026340-2nf97zvc	349	24	for	for	IN
cord-026340-2nf97zvc	349	25	the	the	DT
cord-026340-2nf97zvc	349	26	treatment	treatment	NN
cord-026340-2nf97zvc	349	27	of	of	IN
cord-026340-2nf97zvc	349	28	novel	novel	JJ
cord-026340-2nf97zvc	349	29	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	349	30	pneumonia	pneumonia	NN
cord-026340-2nf97zvc	349	31	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-026340-2nf97zvc	349	32	prophylaxis	prophylaxis	NN
cord-026340-2nf97zvc	349	33	for	for	IN
cord-026340-2nf97zvc	349	34	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	349	35	contacts	contact	NNS
cord-026340-2nf97zvc	349	36	in	in	IN
cord-026340-2nf97zvc	349	37	India	India	NNP
cord-026340-2nf97zvc	349	38	Molecular	Molecular	NNP
cord-026340-2nf97zvc	349	39	evolution	evolution	NN
cord-026340-2nf97zvc	349	40	analysis	analysis	NN
cord-026340-2nf97zvc	349	41	and	and	CC
cord-026340-2nf97zvc	349	42	geographic	geographic	JJ
cord-026340-2nf97zvc	349	43	investigation	investigation	NN
cord-026340-2nf97zvc	349	44	of	of	IN
cord-026340-2nf97zvc	349	45	severe	severe	JJ
cord-026340-2nf97zvc	349	46	acute	acute	JJ
cord-026340-2nf97zvc	349	47	respiratory	respiratory	JJ
cord-026340-2nf97zvc	349	48	syndrome	syndrome	NN
cord-026340-2nf97zvc	349	49	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	349	50	-	-	HYPH
cord-026340-2nf97zvc	349	51	like	like	JJ
cord-026340-2nf97zvc	349	52	virus	virus	NN
cord-026340-2nf97zvc	349	53	in	in	IN
cord-026340-2nf97zvc	349	54	palm	palm	NN
cord-026340-2nf97zvc	349	55	civets	civet	NNS
cord-026340-2nf97zvc	349	56	at	at	IN
cord-026340-2nf97zvc	349	57	an	an	DT
cord-026340-2nf97zvc	349	58	animal	animal	NN
cord-026340-2nf97zvc	349	59	market	market	NN
cord-026340-2nf97zvc	349	60	and	and	CC
cord-026340-2nf97zvc	349	61	on	on	IN
cord-026340-2nf97zvc	349	62	farms	farm	NNS
cord-026340-2nf97zvc	349	63	Toll	toll	NN
cord-026340-2nf97zvc	349	64	-	-	HYPH
cord-026340-2nf97zvc	349	65	like	like	JJ
cord-026340-2nf97zvc	349	66	receptors	receptor	NNS
cord-026340-2nf97zvc	349	67	in	in	IN
cord-026340-2nf97zvc	349	68	antiviral	antiviral	JJ
cord-026340-2nf97zvc	349	69	innate	innate	JJ
cord-026340-2nf97zvc	349	70	immunity	immunity	NN
cord-026340-2nf97zvc	349	71	Mitogenic	Mitogenic	NNP
cord-026340-2nf97zvc	349	72	effect	effect	NN
cord-026340-2nf97zvc	349	73	of	of	IN
cord-026340-2nf97zvc	349	74	lysosomal	lysosomal	JJ
cord-026340-2nf97zvc	349	75	hydrolases	hydrolase	NNS
cord-026340-2nf97zvc	349	76	on	on	IN
cord-026340-2nf97zvc	349	77	bovine	bovine	JJ
cord-026340-2nf97zvc	349	78	tracheal	tracheal	NN
cord-026340-2nf97zvc	349	79	myocytes	myocyte	NNS
cord-026340-2nf97zvc	349	80	in	in	IN
cord-026340-2nf97zvc	349	81	culture	culture	NN
cord-026340-2nf97zvc	349	82	Therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	349	83	options	option	NNS
cord-026340-2nf97zvc	349	84	for	for	IN
cord-026340-2nf97zvc	349	85	the	the	DT
cord-026340-2nf97zvc	349	86	2019	2019	CD
cord-026340-2nf97zvc	349	87	novel	novel	NN
cord-026340-2nf97zvc	349	88	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	349	89	(	(	-LRB-
cord-026340-2nf97zvc	349	90	2019-nCoV	2019-ncov	CD
cord-026340-2nf97zvc	349	91	)	)	-RRB-
cord-026340-2nf97zvc	350	1	Viral	viral	JJ
cord-026340-2nf97zvc	350	2	metagenomics	metagenomic	NNS
cord-026340-2nf97zvc	350	3	revealed	reveal	VBD
cord-026340-2nf97zvc	350	4	sendai	sendai	NNP
cord-026340-2nf97zvc	350	5	virus	virus	NN
cord-026340-2nf97zvc	350	6	and	and	CC
cord-026340-2nf97zvc	350	7	corona	corona	NN
cord-026340-2nf97zvc	350	8	virus	virus	NN
cord-026340-2nf97zvc	350	9	infection	infection	NN
cord-026340-2nf97zvc	350	10	of	of	IN
cord-026340-2nf97zvc	350	11	Malayan	malayan	JJ
cord-026340-2nf97zvc	350	12	Pangolins	Pangolins	NNPS
cord-026340-2nf97zvc	350	13	(	(	-LRB-
cord-026340-2nf97zvc	350	14	Malaya	Malaya	NNP
cord-026340-2nf97zvc	350	15	javanica	javanica	NNS
cord-026340-2nf97zvc	350	16	)	)	-RRB-
cord-026340-2nf97zvc	350	17	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-026340-2nf97zvc	350	18	,	,	,
cord-026340-2nf97zvc	350	19	a	a	DT
cord-026340-2nf97zvc	350	20	less	less	RBR
cord-026340-2nf97zvc	350	21	toxic	toxic	JJ
cord-026340-2nf97zvc	350	22	derivative	derivative	NN
cord-026340-2nf97zvc	350	23	of	of	IN
cord-026340-2nf97zvc	350	24	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	350	25	,	,	,
cord-026340-2nf97zvc	350	26	is	be	VBZ
cord-026340-2nf97zvc	350	27	effective	effective	JJ
cord-026340-2nf97zvc	350	28	in	in	IN
cord-026340-2nf97zvc	350	29	inhibiting	inhibit	VBG
cord-026340-2nf97zvc	350	30	SARS	SARS	NNP
cord-026340-2nf97zvc	350	31	-	-	HYPH
cord-026340-2nf97zvc	350	32	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	350	33	infection	infection	NN
cord-026340-2nf97zvc	350	34	in	in	IN
cord-026340-2nf97zvc	350	35	vitro	vitro	FW
cord-026340-2nf97zvc	351	1	Chloroquine	Chloroquine	NNP
cord-026340-2nf97zvc	351	2	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	351	3	autophagic	autophagic	NN
cord-026340-2nf97zvc	351	4	flux	flux	NN
cord-026340-2nf97zvc	351	5	by	by	IN
cord-026340-2nf97zvc	351	6	decreasing	decrease	VBG
cord-026340-2nf97zvc	351	7	autophagosome	autophagosome	JJ
cord-026340-2nf97zvc	351	8	-	-	HYPH
cord-026340-2nf97zvc	351	9	lysosome	lysosome	NN
cord-026340-2nf97zvc	351	10	fusion	fusion	NN
cord-026340-2nf97zvc	351	11	Efficacy	Efficacy	NNP
cord-026340-2nf97zvc	351	12	of	of	IN
cord-026340-2nf97zvc	351	13	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	351	14	for	for	IN
cord-026340-2nf97zvc	351	15	the	the	DT
cord-026340-2nf97zvc	351	16	treatment	treatment	NN
cord-026340-2nf97zvc	351	17	of	of	IN
cord-026340-2nf97zvc	351	18	uncomplicated	uncomplicated	JJ
cord-026340-2nf97zvc	351	19	Plasmodium	Plasmodium	NNP
cord-026340-2nf97zvc	351	20	falciparum	falciparum	NN
cord-026340-2nf97zvc	351	21	malaria	malaria	NN
cord-026340-2nf97zvc	351	22	in	in	IN
cord-026340-2nf97zvc	351	23	Honduras	Honduras	NNP
cord-026340-2nf97zvc	351	24	Welfare	Welfare	NNP
cord-026340-2nf97zvc	351	25	and	and	CC
cord-026340-2nf97zvc	351	26	Sport	Sport	NNP
cord-026340-2nf97zvc	351	27	(	(	-LRB-
cord-026340-2nf97zvc	351	28	2020	2020	CD
cord-026340-2nf97zvc	351	29	)	)	-RRB-
cord-026340-2nf97zvc	352	1	National	National	NNP
cord-026340-2nf97zvc	352	2	Institute	Institute	NNP
cord-026340-2nf97zvc	352	3	for	for	IN
cord-026340-2nf97zvc	352	4	Public	Public	NNP
cord-026340-2nf97zvc	352	5	Health	Health	NNP
cord-026340-2nf97zvc	352	6	and	and	CC
cord-026340-2nf97zvc	352	7	the	the	DT
cord-026340-2nf97zvc	352	8	Environment	Environment	NNP
cord-026340-2nf97zvc	352	9	Molecular	Molecular	NNP
cord-026340-2nf97zvc	352	10	virology	virology	NN
cord-026340-2nf97zvc	353	1	Various	various	JJ
cord-026340-2nf97zvc	353	2	botanical	botanical	JJ
cord-026340-2nf97zvc	353	3	sources	source	NNS
cord-026340-2nf97zvc	353	4	of	of	IN
cord-026340-2nf97zvc	353	5	betulinic	betulinic	JJ
cord-026340-2nf97zvc	353	6	acid	acid	NN
cord-026340-2nf97zvc	353	7	:	:	:
cord-026340-2nf97zvc	353	8	a	a	DT
cord-026340-2nf97zvc	353	9	review	review	NN
cord-026340-2nf97zvc	353	10	Antiviral	antiviral	JJ
cord-026340-2nf97zvc	353	11	activity	activity	NN
cord-026340-2nf97zvc	353	12	of	of	IN
cord-026340-2nf97zvc	353	13	betulin	betulin	NNP
cord-026340-2nf97zvc	353	14	,	,	,
cord-026340-2nf97zvc	353	15	betulinic	betulinic	NNP
cord-026340-2nf97zvc	353	16	and	and	CC
cord-026340-2nf97zvc	353	17	betulonic	betulonic	JJ
cord-026340-2nf97zvc	353	18	acids	acid	NNS
cord-026340-2nf97zvc	353	19	against	against	IN
cord-026340-2nf97zvc	353	20	some	some	DT
cord-026340-2nf97zvc	353	21	enveloped	envelop	VBN
cord-026340-2nf97zvc	353	22	and	and	CC
cord-026340-2nf97zvc	353	23	non	non	JJ
cord-026340-2nf97zvc	353	24	-	-	JJ
cord-026340-2nf97zvc	353	25	enveloped	enveloped	JJ
cord-026340-2nf97zvc	353	26	viruses	virus	NNS
cord-026340-2nf97zvc	353	27	Compliance	compliance	NN
cord-026340-2nf97zvc	353	28	and	and	CC
cord-026340-2nf97zvc	353	29	tolerability	tolerability	NN
cord-026340-2nf97zvc	353	30	of	of	IN
cord-026340-2nf97zvc	353	31	mefloquine	mefloquine	NN
cord-026340-2nf97zvc	353	32	and	and	CC
cord-026340-2nf97zvc	353	33	chloroquine	chloroquine	NNP
cord-026340-2nf97zvc	353	34	plus	plus	CC
cord-026340-2nf97zvc	353	35	proguanil	proguanil	NN
cord-026340-2nf97zvc	353	36	for	for	IN
cord-026340-2nf97zvc	353	37	longterm	longterm	JJ
cord-026340-2nf97zvc	353	38	malaria	malaria	NN
cord-026340-2nf97zvc	353	39	chemoprophylaxis	chemoprophylaxis	NNP
cord-026340-2nf97zvc	353	40	in	in	IN
cord-026340-2nf97zvc	353	41	groups	group	NNS
cord-026340-2nf97zvc	353	42	at	at	IN
cord-026340-2nf97zvc	353	43	particular	particular	JJ
cord-026340-2nf97zvc	353	44	risk	risk	NN
cord-026340-2nf97zvc	353	45	(	(	-LRB-
cord-026340-2nf97zvc	353	46	the	the	DT
cord-026340-2nf97zvc	353	47	military	military	NN
cord-026340-2nf97zvc	353	48	)	)	-RRB-
cord-026340-2nf97zvc	353	49	Coalition	coalition	NN
cord-026340-2nf97zvc	353	50	:	:	:
cord-026340-2nf97zvc	353	51	advocacy	advocacy	NN
cord-026340-2nf97zvc	353	52	for	for	IN
cord-026340-2nf97zvc	353	53	prospective	prospective	JJ
cord-026340-2nf97zvc	353	54	clinical	clinical	JJ
cord-026340-2nf97zvc	353	55	trials	trial	NNS
cord-026340-2nf97zvc	353	56	to	to	TO
cord-026340-2nf97zvc	353	57	test	test	VB
cord-026340-2nf97zvc	353	58	the	the	DT
cord-026340-2nf97zvc	353	59	post	post	NN
cord-026340-2nf97zvc	353	60	exposure	exposure	NN
cord-026340-2nf97zvc	353	61	potential	potential	NN
cord-026340-2nf97zvc	353	62	of	of	IN
cord-026340-2nf97zvc	353	63	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	353	64	against	against	IN
cord-026340-2nf97zvc	353	65	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	353	66	Drug	Drug	NNP
cord-026340-2nf97zvc	353	67	targets	target	NNS
cord-026340-2nf97zvc	353	68	for	for	IN
cord-026340-2nf97zvc	353	69	corona	corona	NN
cord-026340-2nf97zvc	353	70	virus	virus	NN
cord-026340-2nf97zvc	353	71	:	:	:
cord-026340-2nf97zvc	353	72	a	a	DT
cord-026340-2nf97zvc	353	73	systematic	systematic	JJ
cord-026340-2nf97zvc	353	74	review	review	NN
cord-026340-2nf97zvc	354	1	PPT1	PPT1	NNP
cord-026340-2nf97zvc	354	2	promotes	promote	VBZ
cord-026340-2nf97zvc	354	3	tumor	tumor	NN
cord-026340-2nf97zvc	354	4	growth	growth	NN
cord-026340-2nf97zvc	354	5	and	and	CC
cord-026340-2nf97zvc	354	6	is	be	VBZ
cord-026340-2nf97zvc	354	7	the	the	DT
cord-026340-2nf97zvc	354	8	molecular	molecular	JJ
cord-026340-2nf97zvc	354	9	target	target	NN
cord-026340-2nf97zvc	354	10	of	of	IN
cord-026340-2nf97zvc	354	11	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	354	12	derivatives	derivative	NNS
cord-026340-2nf97zvc	354	13	in	in	IN
cord-026340-2nf97zvc	354	14	cancer	cancer	NN
cord-026340-2nf97zvc	354	15	Inhibition	inhibition	NN
cord-026340-2nf97zvc	354	16	of	of	IN
cord-026340-2nf97zvc	354	17	betulinic	betulinic	JJ
cord-026340-2nf97zvc	354	18	acid	acid	NN
cord-026340-2nf97zvc	354	19	to	to	IN
cord-026340-2nf97zvc	354	20	growth	growth	NN
cord-026340-2nf97zvc	354	21	and	and	CC
cord-026340-2nf97zvc	354	22	angiogenesis	angiogenesis	NN
cord-026340-2nf97zvc	354	23	of	of	IN
cord-026340-2nf97zvc	354	24	human	human	JJ
cord-026340-2nf97zvc	354	25	colorectal	colorectal	JJ
cord-026340-2nf97zvc	354	26	cancer	cancer	NN
cord-026340-2nf97zvc	354	27	cell	cell	NN
cord-026340-2nf97zvc	354	28	in	in	IN
cord-026340-2nf97zvc	354	29	nude	nude	JJ
cord-026340-2nf97zvc	354	30	mice	mouse	NNS
cord-026340-2nf97zvc	354	31	Effects	effect	NNS
cord-026340-2nf97zvc	354	32	of	of	IN
cord-026340-2nf97zvc	354	33	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	354	34	on	on	IN
cord-026340-2nf97zvc	354	35	viral	viral	JJ
cord-026340-2nf97zvc	354	36	infections	infection	NNS
cord-026340-2nf97zvc	354	37	:	:	:
cord-026340-2nf97zvc	354	38	an	an	DT
cord-026340-2nf97zvc	354	39	old	old	JJ
cord-026340-2nf97zvc	354	40	drug	drug	NN
cord-026340-2nf97zvc	354	41	against	against	IN
cord-026340-2nf97zvc	354	42	today	today	NN
cord-026340-2nf97zvc	354	43	's	's	POS
cord-026340-2nf97zvc	354	44	diseases	disease	NNS
cord-026340-2nf97zvc	354	45	?	?	.
cord-026340-2nf97zvc	355	1	Coronavirus	Coronavirus	NNP
cord-026340-2nf97zvc	355	2	envelope	envelope	NN
cord-026340-2nf97zvc	355	3	protein	protein	NN
cord-026340-2nf97zvc	355	4	:	:	:
cord-026340-2nf97zvc	355	5	current	current	JJ
cord-026340-2nf97zvc	355	6	knowledge	knowledge	NN
cord-026340-2nf97zvc	355	7	Mechanisms	Mechanisms	NNPS
cord-026340-2nf97zvc	355	8	of	of	IN
cord-026340-2nf97zvc	355	9	action	action	NN
cord-026340-2nf97zvc	355	10	of	of	IN
cord-026340-2nf97zvc	355	11	hydroxychloroquine	hydroxychloroquine	NNP
cord-026340-2nf97zvc	355	12	and	and	CC
cord-026340-2nf97zvc	355	13	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	355	14	:	:	:
cord-026340-2nf97zvc	355	15	implications	implication	NNS
cord-026340-2nf97zvc	355	16	for	for	IN
cord-026340-2nf97zvc	355	17	rheumatology	rheumatology	NN
cord-026340-2nf97zvc	355	18	A	a	DT
cord-026340-2nf97zvc	355	19	systematic	systematic	JJ
cord-026340-2nf97zvc	355	20	review	review	NN
cord-026340-2nf97zvc	355	21	of	of	IN
cord-026340-2nf97zvc	355	22	the	the	DT
cord-026340-2nf97zvc	355	23	prophylactic	prophylactic	JJ
cord-026340-2nf97zvc	355	24	role	role	NN
cord-026340-2nf97zvc	355	25	of	of	IN
cord-026340-2nf97zvc	355	26	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	355	27	and	and	CC
cord-026340-2nf97zvc	355	28	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	355	29	in	in	IN
cord-026340-2nf97zvc	355	30	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	355	31	disease-19	disease-19	CD
cord-026340-2nf97zvc	355	32	(	(	-LRB-
cord-026340-2nf97zvc	356	1	COVID-19	covid-19	LS
cord-026340-2nf97zvc	356	2	)	)	-RRB-
cord-026340-2nf97zvc	356	3	Chloroquine	Chloroquine	NNP
cord-026340-2nf97zvc	356	4	for	for	IN
cord-026340-2nf97zvc	356	5	SARS	SARS	NNP
cord-026340-2nf97zvc	356	6	-	-	HYPH
cord-026340-2nf97zvc	356	7	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	356	8	:	:	:
cord-026340-2nf97zvc	356	9	implications	implication	NNS
cord-026340-2nf97zvc	356	10	of	of	IN
cord-026340-2nf97zvc	356	11	its	-PRON-	PRP$
cord-026340-2nf97zvc	356	12	unique	unique	JJ
cord-026340-2nf97zvc	356	13	pharmacokinetic	pharmacokinetic	JJ
cord-026340-2nf97zvc	356	14	and	and	CC
cord-026340-2nf97zvc	356	15	safety	safety	NN
cord-026340-2nf97zvc	356	16	properties	property	NNS
cord-026340-2nf97zvc	356	17	Into	into	IN
cord-026340-2nf97zvc	356	18	the	the	DT
cord-026340-2nf97zvc	356	19	eye	eye	NN
cord-026340-2nf97zvc	356	20	of	of	IN
cord-026340-2nf97zvc	356	21	the	the	DT
cord-026340-2nf97zvc	356	22	cytokine	cytokine	NN
cord-026340-2nf97zvc	356	23	storm	storm	NN
cord-026340-2nf97zvc	356	24	Toll	Toll	NNP
cord-026340-2nf97zvc	356	25	-	-	HYPH
cord-026340-2nf97zvc	356	26	like	like	JJ
cord-026340-2nf97zvc	356	27	receptor	receptor	NN
cord-026340-2nf97zvc	356	28	3	3	CD
cord-026340-2nf97zvc	356	29	signaling	signal	VBG
cord-026340-2nf97zvc	356	30	via	via	IN
cord-026340-2nf97zvc	356	31	TRIF	TRIF	NNP
cord-026340-2nf97zvc	356	32	contributes	contribute	VBZ
cord-026340-2nf97zvc	356	33	to	to	IN
cord-026340-2nf97zvc	356	34	a	a	DT
cord-026340-2nf97zvc	356	35	protective	protective	JJ
cord-026340-2nf97zvc	356	36	innate	innate	JJ
cord-026340-2nf97zvc	356	37	immune	immune	JJ
cord-026340-2nf97zvc	356	38	response	response	NN
cord-026340-2nf97zvc	356	39	to	to	IN
cord-026340-2nf97zvc	357	1	severe	severe	JJ
cord-026340-2nf97zvc	357	2	acute	acute	JJ
cord-026340-2nf97zvc	357	3	respiratory	respiratory	JJ
cord-026340-2nf97zvc	357	4	syndrome	syndrome	NN
cord-026340-2nf97zvc	357	5	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	357	6	infection	infection	NN
cord-026340-2nf97zvc	357	7	Betulinic	Betulinic	NNP
cord-026340-2nf97zvc	357	8	acid	acid	NN
cord-026340-2nf97zvc	357	9	inhibits	inhibit	VBZ
cord-026340-2nf97zvc	357	10	endotoxin	endotoxin	NN
cord-026340-2nf97zvc	357	11	-	-	HYPH
cord-026340-2nf97zvc	357	12	stimulated	stimulate	VBN
cord-026340-2nf97zvc	357	13	phosphorylation	phosphorylation	NN
cord-026340-2nf97zvc	357	14	cascade	cascade	NN
cord-026340-2nf97zvc	357	15	and	and	CC
cord-026340-2nf97zvc	357	16	pro	pro	JJ
cord-026340-2nf97zvc	357	17	-	-	JJ
cord-026340-2nf97zvc	357	18	inflammatory	inflammatory	JJ
cord-026340-2nf97zvc	357	19	prostaglandin	prostaglandin	NN
cord-026340-2nf97zvc	357	20	E(2	E(2	NNP
cord-026340-2nf97zvc	357	21	)	)	-RRB-
cord-026340-2nf97zvc	357	22	production	production	NN
cord-026340-2nf97zvc	357	23	in	in	IN
cord-026340-2nf97zvc	357	24	human	human	JJ
cord-026340-2nf97zvc	357	25	peripheral	peripheral	JJ
cord-026340-2nf97zvc	357	26	blood	blood	NN
cord-026340-2nf97zvc	357	27	mononuclear	mononuclear	NN
cord-026340-2nf97zvc	357	28	cells	cell	NNS
cord-026340-2nf97zvc	358	1	Chloroquine	Chloroquine	NNP
cord-026340-2nf97zvc	358	2	is	be	VBZ
cord-026340-2nf97zvc	358	3	a	a	DT
cord-026340-2nf97zvc	358	4	potent	potent	JJ
cord-026340-2nf97zvc	358	5	inhibitor	inhibitor	NN
cord-026340-2nf97zvc	358	6	of	of	IN
cord-026340-2nf97zvc	358	7	SARS	SARS	NNP
cord-026340-2nf97zvc	358	8	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	358	9	infection	infection	NN
cord-026340-2nf97zvc	358	10	and	and	CC
cord-026340-2nf97zvc	358	11	spread	spread	VBD
cord-026340-2nf97zvc	358	12	David	David	NNP
cord-026340-2nf97zvc	358	13	Veesler	Veesler	NNP
cord-026340-2nf97zvc	358	14	D	D	NNP
cord-026340-2nf97zvc	358	15	(	(	-LRB-
cord-026340-2nf97zvc	358	16	2020	2020	CD
cord-026340-2nf97zvc	358	17	)	)	-RRB-
cord-026340-2nf97zvc	358	18	Structure	structure	NN
cord-026340-2nf97zvc	358	19	,	,	,
cord-026340-2nf97zvc	358	20	function	function	NN
cord-026340-2nf97zvc	358	21	,	,	,
cord-026340-2nf97zvc	358	22	and	and	CC
cord-026340-2nf97zvc	358	23	antigenicity	antigenicity	NN
cord-026340-2nf97zvc	358	24	of	of	IN
cord-026340-2nf97zvc	358	25	the	the	DT
cord-026340-2nf97zvc	358	26	SARS	SARS	NNP
cord-026340-2nf97zvc	358	27	-	-	HYPH
cord-026340-2nf97zvc	358	28	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	358	29	spike	spike	NN
cord-026340-2nf97zvc	358	30	glycoprotein	glycoprotein	NN
cord-026340-2nf97zvc	358	31	Increasing	increase	VBG
cord-026340-2nf97zvc	358	32	host	host	NN
cord-026340-2nf97zvc	358	33	cellular	cellular	JJ
cord-026340-2nf97zvc	358	34	receptor	receptor	NN
cord-026340-2nf97zvc	358	35	-	-	HYPH
cord-026340-2nf97zvc	358	36	angiotensin	angiotensin	NN
cord-026340-2nf97zvc	358	37	-	-	HYPH
cord-026340-2nf97zvc	358	38	converting	convert	VBG
cord-026340-2nf97zvc	358	39	enzyme	enzyme	NN
cord-026340-2nf97zvc	358	40	2	2	CD
cord-026340-2nf97zvc	358	41	(	(	-LRB-
cord-026340-2nf97zvc	358	42	ACE2	ACE2	NNP
cord-026340-2nf97zvc	358	43	)	)	-RRB-
cord-026340-2nf97zvc	358	44	expression	expression	NN
cord-026340-2nf97zvc	358	45	by	by	IN
cord-026340-2nf97zvc	358	46	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	358	47	may	may	MD
cord-026340-2nf97zvc	358	48	facilitate	facilitate	VB
cord-026340-2nf97zvc	358	49	2019-nCoV	2019-ncov	CD
cord-026340-2nf97zvc	358	50	infection	infection	NN
cord-026340-2nf97zvc	359	1	The	the	DT
cord-026340-2nf97zvc	359	2	pathogenesis	pathogenesis	NN
cord-026340-2nf97zvc	359	3	and	and	CC
cord-026340-2nf97zvc	359	4	treatment	treatment	NN
cord-026340-2nf97zvc	359	5	of	of	IN
cord-026340-2nf97zvc	359	6	the	the	DT
cord-026340-2nf97zvc	359	7	cytokine	cytokine	NN
cord-026340-2nf97zvc	359	8	storn	storn	NN
cord-026340-2nf97zvc	359	9	in	in	IN
cord-026340-2nf97zvc	359	10	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	359	11	SARS	SARS	NNP
cord-026340-2nf97zvc	359	12	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	359	13	entry	entry	NN
cord-026340-2nf97zvc	359	14	into	into	IN
cord-026340-2nf97zvc	359	15	host	host	NN
cord-026340-2nf97zvc	359	16	cells	cell	NNS
cord-026340-2nf97zvc	359	17	through	through	IN
cord-026340-2nf97zvc	359	18	a	a	DT
cord-026340-2nf97zvc	359	19	novel	novel	JJ
cord-026340-2nf97zvc	359	20	clathrin	clathrin	NN
cord-026340-2nf97zvc	359	21	-	-	:
cord-026340-2nf97zvc	359	22	and	and	CC
cord-026340-2nf97zvc	359	23	caveolae	caveolae	JJ
cord-026340-2nf97zvc	359	24	-	-	HYPH
cord-026340-2nf97zvc	359	25	independent	independent	JJ
cord-026340-2nf97zvc	359	26	endocytic	endocytic	JJ
cord-026340-2nf97zvc	359	27	pathway	pathway	NN
cord-026340-2nf97zvc	359	28	Update	update	NN
cord-026340-2nf97zvc	359	29	95-SARS	95-sars	CD
cord-026340-2nf97zvc	359	30	:	:	:
cord-026340-2nf97zvc	359	31	chronology	chronology	NN
cord-026340-2nf97zvc	359	32	of	of	IN
cord-026340-2nf97zvc	359	33	a	a	DT
cord-026340-2nf97zvc	359	34	serial	serial	JJ
cord-026340-2nf97zvc	359	35	killer	killer	NN
cord-026340-2nf97zvc	359	36	Landscape	landscape	NN
cord-026340-2nf97zvc	359	37	analysis	analysis	NN
cord-026340-2nf97zvc	359	38	of	of	IN
cord-026340-2nf97zvc	359	39	therapeutics	therapeutic	NNS
cord-026340-2nf97zvc	359	40	as	as	IN
cord-026340-2nf97zvc	359	41	21st	21st	JJ
cord-026340-2nf97zvc	359	42	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	359	43	)	)	-RRB-
cord-026340-2nf97zvc	359	44	Pandemic	Pandemic	NNP
cord-026340-2nf97zvc	359	45	.	.	.
cord-026340-2nf97zvc	360	1	Report	report	NN
cord-026340-2nf97zvc	360	2	of	of	IN
cord-026340-2nf97zvc	360	3	a	a	DT
cord-026340-2nf97zvc	360	4	WHO	WHO	NNP
cord-026340-2nf97zvc	360	5	scientific	scientific	JJ
cord-026340-2nf97zvc	360	6	group	group	NN
cord-026340-2nf97zvc	360	7	pH	ph	NN
cord-026340-2nf97zvc	360	8	-	-	HYPH
cord-026340-2nf97zvc	360	9	dependent	dependent	JJ
cord-026340-2nf97zvc	360	10	entry	entry	NN
cord-026340-2nf97zvc	360	11	of	of	IN
cord-026340-2nf97zvc	360	12	severe	severe	JJ
cord-026340-2nf97zvc	360	13	acute	acute	JJ
cord-026340-2nf97zvc	360	14	respiratory	respiratory	JJ
cord-026340-2nf97zvc	360	15	syndrome	syndrome	NN
cord-026340-2nf97zvc	360	16	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	360	17	is	be	VBZ
cord-026340-2nf97zvc	360	18	mediated	mediate	VBN
cord-026340-2nf97zvc	360	19	by	by	IN
cord-026340-2nf97zvc	360	20	the	the	DT
cord-026340-2nf97zvc	360	21	spike	spike	NN
cord-026340-2nf97zvc	360	22	glycoprotein	glycoprotein	NN
cord-026340-2nf97zvc	360	23	and	and	CC
cord-026340-2nf97zvc	360	24	enhanced	enhance	VBN
cord-026340-2nf97zvc	360	25	by	by	IN
cord-026340-2nf97zvc	360	26	dendritic	dendritic	JJ
cord-026340-2nf97zvc	360	27	cell	cell	NN
cord-026340-2nf97zvc	360	28	transfer	transfer	NN
cord-026340-2nf97zvc	360	29	through	through	IN
cord-026340-2nf97zvc	360	30	DC	DC	NNP
cord-026340-2nf97zvc	360	31	-	-	HYPH
cord-026340-2nf97zvc	360	32	SIGN	SIGN	NNP
cord-026340-2nf97zvc	361	1	In	in	IN
cord-026340-2nf97zvc	361	2	vitro	vitro	FW
cord-026340-2nf97zvc	361	3	antiviral	antiviral	JJ
cord-026340-2nf97zvc	361	4	activity	activity	NN
cord-026340-2nf97zvc	361	5	and	and	CC
cord-026340-2nf97zvc	361	6	projection	projection	NN
cord-026340-2nf97zvc	361	7	of	of	IN
cord-026340-2nf97zvc	361	8	optimized	optimize	VBN
cord-026340-2nf97zvc	361	9	dosing	dosing	NN
cord-026340-2nf97zvc	361	10	design	design	NN
cord-026340-2nf97zvc	361	11	of	of	IN
cord-026340-2nf97zvc	361	12	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	361	13	for	for	IN
cord-026340-2nf97zvc	361	14	the	the	DT
cord-026340-2nf97zvc	361	15	treatment	treatment	NN
cord-026340-2nf97zvc	361	16	of	of	IN
cord-026340-2nf97zvc	361	17	severe	severe	JJ
cord-026340-2nf97zvc	361	18	acute	acute	JJ
cord-026340-2nf97zvc	361	19	respiratory	respiratory	JJ
cord-026340-2nf97zvc	361	20	syndrome	syndrome	NN
cord-026340-2nf97zvc	361	21	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	361	22	2	2	CD
cord-026340-2nf97zvc	362	1	(	(	-LRB-
cord-026340-2nf97zvc	362	2	SARS	SARS	NNP
cord-026340-2nf97zvc	362	3	-	-	HYPH
cord-026340-2nf97zvc	362	4	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	362	5	)	)	-RRB-
cord-026340-2nf97zvc	363	1	Use	Use	NNP
cord-026340-2nf97zvc	363	2	of	of	IN
cord-026340-2nf97zvc	363	3	hydroxychloroquine	hydroxychloroquine	NN
cord-026340-2nf97zvc	363	4	and	and	CC
cord-026340-2nf97zvc	363	5	chloroquine	chloroquine	NN
cord-026340-2nf97zvc	363	6	during	during	IN
cord-026340-2nf97zvc	363	7	the	the	DT
cord-026340-2nf97zvc	363	8	COVID-19	COVID-19	NNP
cord-026340-2nf97zvc	363	9	pandemic	pandemic	NN
cord-026340-2nf97zvc	363	10	:	:	:
cord-026340-2nf97zvc	363	11	what	what	WP
cord-026340-2nf97zvc	363	12	every	every	DT
cord-026340-2nf97zvc	363	13	clinician	clinician	NN
cord-026340-2nf97zvc	363	14	should	should	MD
cord-026340-2nf97zvc	363	15	know	know	VB
cord-026340-2nf97zvc	363	16	Probable	probable	JJ
cord-026340-2nf97zvc	363	17	pangolin	pangolin	NN
cord-026340-2nf97zvc	363	18	origin	origin	NN
cord-026340-2nf97zvc	363	19	of	of	IN
cord-026340-2nf97zvc	363	20	SARS	SARS	NNP
cord-026340-2nf97zvc	363	21	-	-	HYPH
cord-026340-2nf97zvc	363	22	CoV-2	CoV-2	NNP
cord-026340-2nf97zvc	363	23	associated	associate	VBN
cord-026340-2nf97zvc	363	24	with	with	IN
cord-026340-2nf97zvc	363	25	the	the	DT
cord-026340-2nf97zvc	363	26	COVID-19	covid-19	JJ
cord-026340-2nf97zvc	363	27	outbreak	outbreak	NN
cord-026340-2nf97zvc	363	28	Protecting	protect	VBG
cord-026340-2nf97zvc	363	29	Chinese	chinese	JJ
cord-026340-2nf97zvc	363	30	healthcare	healthcare	NN
cord-026340-2nf97zvc	363	31	workers	worker	NNS
cord-026340-2nf97zvc	363	32	while	while	IN
cord-026340-2nf97zvc	363	33	combating	combat	VBG
cord-026340-2nf97zvc	363	34	the	the	DT
cord-026340-2nf97zvc	363	35	2019	2019	CD
cord-026340-2nf97zvc	363	36	novel	novel	NN
cord-026340-2nf97zvc	363	37	coronavirus	coronavirus	NN
cord-026340-2nf97zvc	363	38	Coronaviruses	Coronaviruses	NNP
cord-026340-2nf97zvc	363	39	-	-	HYPH
cord-026340-2nf97zvc	363	40	drug	drug	NN
cord-026340-2nf97zvc	363	41	discovery	discovery	NN
cord-026340-2nf97zvc	363	42	and	and	CC
cord-026340-2nf97zvc	363	43	therapeutic	therapeutic	JJ
cord-026340-2nf97zvc	363	44	options	option	NNS
cord-026340-2nf97zvc	364	1	Publisher	publisher	NN
cord-026340-2nf97zvc	364	2	's	's	POS
cord-026340-2nf97zvc	364	3	Note	Note	NNP
cord-026340-2nf97zvc	364	4	Springer	Springer	NNP
cord-026340-2nf97zvc	364	5	Nature	Nature	NNP
cord-026340-2nf97zvc	364	6	remains	remain	VBZ
cord-026340-2nf97zvc	364	7	neutral	neutral	JJ
cord-026340-2nf97zvc	364	8	with	with	IN
cord-026340-2nf97zvc	364	9	regard	regard	NN
cord-026340-2nf97zvc	364	10	to	to	IN
cord-026340-2nf97zvc	364	11	jurisdictional	jurisdictional	JJ
cord-026340-2nf97zvc	364	12	claims	claim	NNS
cord-026340-2nf97zvc	364	13	in	in	IN
cord-026340-2nf97zvc	364	14	published	publish	VBN
cord-026340-2nf97zvc	364	15	maps	map	NNS
cord-026340-2nf97zvc	364	16	and	and	CC
cord-026340-2nf97zvc	364	17	institutional	institutional	JJ
cord-026340-2nf97zvc	364	18	affiliations	affiliation	NNS
cord-026340-2nf97zvc	364	19	.	.	.