id author title date pages extension mime words sentences flesch summary cache txt cord-267762-mzon01fd Ferreira, A. Chronic treatment with hydroxychloroquine and SARS-CoV-2 infection. 2020-06-29 .txt text/plain 2939 167 51 Methods: By analyzing the Portuguese anonymized data on private and public based medical prescriptions we have identified all cases chronically receiving HCQ for the management of diseases such as systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases. Cross linking the two sets of data has allowed us to compare the proportion of HCQ chronic treatment (at least 2 grams per month) in laboratory confirmed cases of SARS-CoV-2 infection with laboratory confirmed negative cases. Several in vitro studies have shown chloroquine phosphate and hydroxychloroquine sulphate (HCQ) to be effective in both preventing and treating SARS-CoV-2 infection in isolated cells (1) (2) (3) . By analyzing these sets of data, we were able to detect all patients with SARS-CoV-2 confirmed infections and all clinically suspected but non-confirmed patients between Mars 2, 2020 (the date of the first Portuguese case) and the moment of the analysis. The proportion of HCQ chronic treatment was higher in negative patients is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. ./cache/cord-267762-mzon01fd.txt ./txt/cord-267762-mzon01fd.txt