id author title date pages extension mime words sentences flesch summary cache txt cord-334150-t6n95laz PENG, LIANG Serum proteomics analysis and comparisons using iTRAQ in the progression of hepatitis B 2013-09-18 .txt text/plain 3190 152 44 The aim of this study was to analyze the changes in serum protein levels in the progression of hepatitis B using isobaric tags for relative and absolute quantitation (iTRAQ) analysis, in addition to comparing the serum protein levels of patients with chronic hepatitis B (CHB), patients with hepatitis B virus-induced acute-on-chronic liver failure (HBV-induced ACLF) and normal individuals. Five of those proteins, C-reactive protein precursor, hemoglobin β chain variant Hb S-Wake, apolipoprotein J precursor, platelet factor 4 precursor and vitronectin, which demonstrated the greatest differences in their expression levels and the most significant correlation with liver diseases, were subsequently verified using western blotting. The purpose of this study was to analyze serum protein levels using iTRAQ in normal controls, as well as patients with chronic hepatitis B (CHB) and HBV-induced ACLF, and to verify those results using western blotting. The aim of this study was to describe the changes in serum protein levels in patients with CHB and HBV-induced ACLF, respectively, compared with healthy controls using iTRAQ and western blotting. ./cache/cord-334150-t6n95laz.txt ./txt/cord-334150-t6n95laz.txt