id author title date pages extension mime words sentences flesch summary cache txt cord-337644-aobdzwpx Pianta, L. Acetic acid disinfection as a potential adjunctive therapy for non-severe COVID-19 2020-05-24 .txt text/plain 1742 94 53 CONCLUSIONS: Considering its potential benefits and high availability, acetic acid disinfection appears to be a promising adjunctive therapy in cases of non-severe COVID-19 and deserves further investigation. Therefore, considering these antiviral properties and that the upper airways are the main site of SARS-CoV-2 entry and replication, we have explored the use of this historical therapy in early-stage cases of COVID-19 by evaluating patients who were administered a disinfecting formulation of acetic acid as an intranasal aerosol. Patients treated with off-label hydroxychloroquine and lopinavir/ritonavir, the standard treatment prescribed at that time, were included in group 1, whereas group 2 was composed of patients treated with hydroxychloroquine only, combined with acetic acid nasal disinfectant at a 0.34% concentration. Acetic acid disinfection could not only improve the clinical course of COVID-19, but also reduce viral load in the airway and in the droplets exhaled by infected individuals. ./cache/cord-337644-aobdzwpx.txt ./txt/cord-337644-aobdzwpx.txt