id author title date pages extension mime words sentences flesch summary cache txt cord-333334-90q1xkld Shengchen, D. Evaluation of a molecular point-of-care testing for viral and atypical pathogens on intravenous antibiotic duration in hospitalized adults with lower respiratory tract infection: a randomized clinical trial 2019-06-20 .txt text/plain 3880 182 38 title: Evaluation of a molecular point-of-care testing for viral and atypical pathogens on intravenous antibiotic duration in hospitalized adults with lower respiratory tract infection: a randomized clinical trial OBJECTIVES: The primary objective was to evaluate whether a molecular point-of-care test (POCT) for viral and atypical pathogens added to routine real-time PCR could reduce duration of intravenous antibiotics in hospitalized patients with lower respiratory tract infection (LRTI) compared with routine real-time PCR. The median and interquartile range of the primary outcome (duration of intravenous antibiotics) and secondary outcomes, including length of hospital stay, cost of intravenous antibiotics and cost of hospitalization, were calculated and the difference between intervention and control group was compared using the Wilcoxon rank-sum test. In conclusion, this study found the addition of molecular POCT testing to routine real-time PCR testing for respiratory viruses and atypical pathogens might help to reduce intravenous antibiotic use in LRTI patients without resulting in adverse outcomes. ./cache/cord-333334-90q1xkld.txt ./txt/cord-333334-90q1xkld.txt