id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-018813-9hoksa86	Waito, Marianne	A Mathematical Model of Cytokine Dynamics During a Cytokine Storm	2016-02-17		.txt	text/plain	2893	156	52	The dynamics of cytokines during normal immune responses and even more so during storms are highly complex and little is known about specific interactions [5, 27] . Combining these approaches can result in major advancements in both the understanding of cancer and immune system dynamics including cytokine interactions, with the potential to identify strategies to control toxic cytokine storms [26] . Following administration of a highly attenuated virus to mice with leukocytes lacking the type I IFN receptor, a deadly cytokine storm developed leading to death in only 24 h. Data was collected and provided by Dr. Byram Bridle, Dr. Scott Walsh and Alexandra Rasiuk who study the role of type I IFN signalling in the regulation of cytokine responses at the OVC. The model provides an accurate fit to the cytokine time series data for both IFNAR-knockout and wild-type mice (not shown).	./cache/cord-018813-9hoksa86.txt	./txt/cord-018813-9hoksa86.txt