id	sid	tid	token	lemma	pos
cord-329515-ra20actc	1	1	key	key	NN
cord-329515-ra20actc	1	2	:	:	:
cord-329515-ra20actc	1	3	cord-329515-ra20actc	cord-329515-ra20actc	NN
cord-329515-ra20actc	1	4	authors	author	NNS
cord-329515-ra20actc	1	5	:	:	:
cord-329515-ra20actc	2	1	nan	nan	NNP
cord-329515-ra20actc	2	2	title	title	NN
cord-329515-ra20actc	2	3	:	:	:
cord-329515-ra20actc	2	4	Retention	Retention	NNP
cord-329515-ra20actc	2	5	of	of	IN
cord-329515-ra20actc	2	6	p63	p63	CD
cord-329515-ra20actc	2	7	in	in	IN
cord-329515-ra20actc	2	8	an	an	DT
cord-329515-ra20actc	2	9	ER	ER	NNP
cord-329515-ra20actc	2	10	-	-	HYPH
cord-329515-ra20actc	2	11	Golgi	Golgi	NNP
cord-329515-ra20actc	2	12	intermediate	intermediate	JJ
cord-329515-ra20actc	2	13	compartment	compartment	NN
cord-329515-ra20actc	2	14	depends	depend	VBZ
cord-329515-ra20actc	2	15	on	on	IN
cord-329515-ra20actc	2	16	the	the	DT
cord-329515-ra20actc	2	17	presence	presence	NN
cord-329515-ra20actc	2	18	of	of	IN
cord-329515-ra20actc	2	19	all	all	DT
cord-329515-ra20actc	2	20	three	three	CD
cord-329515-ra20actc	2	21	of	of	IN
cord-329515-ra20actc	2	22	its	-PRON-	PRP$
cord-329515-ra20actc	2	23	domains	domain	NNS
cord-329515-ra20actc	2	24	and	and	CC
cord-329515-ra20actc	2	25	on	on	IN
cord-329515-ra20actc	2	26	its	-PRON-	PRP$
cord-329515-ra20actc	2	27	ability	ability	NN
cord-329515-ra20actc	2	28	to	to	TO
cord-329515-ra20actc	2	29	form	form	VB
cord-329515-ra20actc	2	30	oligomers	oligomer	NNS
cord-329515-ra20actc	2	31	date	date	NN
cord-329515-ra20actc	2	32	:	:	:
cord-329515-ra20actc	2	33	1994	1994	CD
cord-329515-ra20actc	2	34	-	-	SYM
cord-329515-ra20actc	2	35	07	07	CD
cord-329515-ra20actc	2	36	-	-	HYPH
cord-329515-ra20actc	2	37	01	01	CD
cord-329515-ra20actc	2	38	journal	journal	NN
cord-329515-ra20actc	2	39	:	:	:
cord-329515-ra20actc	3	1	J	J	NNP
cord-329515-ra20actc	3	2	Cell	Cell	NNP
cord-329515-ra20actc	3	3	Biol	Biol	NNP
cord-329515-ra20actc	3	4	DOI	DOI	NNP
cord-329515-ra20actc	3	5	:	:	:
cord-329515-ra20actc	4	1	nan	nan	NNP
cord-329515-ra20actc	4	2	sha	sha	NNP
cord-329515-ra20actc	4	3	:	:	:
cord-329515-ra20actc	4	4	d657cc5e24009f5081425da4d8c3b6467b85df1d	d657cc5e24009f5081425da4d8c3b6467b85df1d	NNP
cord-329515-ra20actc	4	5	doc_id	doc_id	NNP
cord-329515-ra20actc	4	6	:	:	:
cord-329515-ra20actc	4	7	329515	329515	CD
cord-329515-ra20actc	4	8	cord_uid	cord_uid	NNS
cord-329515-ra20actc	4	9	:	:	:
cord-329515-ra20actc	4	10	ra20actc	ra20actc	NNP
cord-329515-ra20actc	5	1	The	the	DT
cord-329515-ra20actc	5	2	type	type	NN
cord-329515-ra20actc	5	3	II	II	NNP
cord-329515-ra20actc	5	4	membrane	membrane	NN
cord-329515-ra20actc	5	5	protein	protein	NN
cord-329515-ra20actc	5	6	p63	p63	CD
cord-329515-ra20actc	5	7	is	be	VBZ
cord-329515-ra20actc	5	8	a	a	DT
cord-329515-ra20actc	5	9	resident	resident	JJ
cord-329515-ra20actc	5	10	protein	protein	NN
cord-329515-ra20actc	5	11	of	of	IN
cord-329515-ra20actc	5	12	a	a	DT
cord-329515-ra20actc	5	13	membrane	membrane	NN
cord-329515-ra20actc	5	14	network	network	NN
cord-329515-ra20actc	5	15	interposed	interpose	VBN
cord-329515-ra20actc	5	16	between	between	IN
cord-329515-ra20actc	5	17	rough	rough	JJ
cord-329515-ra20actc	5	18	ER	ER	NNP
cord-329515-ra20actc	5	19	and	and	CC
cord-329515-ra20actc	5	20	Golgi	Golgi	NNP
cord-329515-ra20actc	5	21	apparatus	apparatus	NN
cord-329515-ra20actc	5	22	.	.	.
cord-329515-ra20actc	6	1	To	to	TO
cord-329515-ra20actc	6	2	study	study	VB
cord-329515-ra20actc	6	3	the	the	DT
cord-329515-ra20actc	6	4	retention	retention	NN
cord-329515-ra20actc	6	5	of	of	IN
cord-329515-ra20actc	6	6	p63	p63	CD
cord-329515-ra20actc	6	7	,	,	,
cord-329515-ra20actc	6	8	mutant	mutant	JJ
cord-329515-ra20actc	6	9	forms	form	NNS
cord-329515-ra20actc	6	10	were	be	VBD
cord-329515-ra20actc	6	11	expressed	express	VBN
cord-329515-ra20actc	6	12	in	in	IN
cord-329515-ra20actc	6	13	COS	COS	NNP
cord-329515-ra20actc	6	14	cells	cell	NNS
cord-329515-ra20actc	6	15	and	and	CC
cord-329515-ra20actc	6	16	the	the	DT
cord-329515-ra20actc	6	17	intracellular	intracellular	JJ
cord-329515-ra20actc	6	18	distribution	distribution	NN
cord-329515-ra20actc	6	19	determined	determine	VBN
cord-329515-ra20actc	6	20	by	by	IN
cord-329515-ra20actc	6	21	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	6	22	microscopy	microscopy	NN
cord-329515-ra20actc	6	23	.	.	.
cord-329515-ra20actc	7	1	Investigation	investigation	NN
cord-329515-ra20actc	7	2	of	of	IN
cord-329515-ra20actc	7	3	chimeric	chimeric	JJ
cord-329515-ra20actc	7	4	constructs	construct	NNS
cord-329515-ra20actc	7	5	between	between	IN
cord-329515-ra20actc	7	6	p63	p63	CD
cord-329515-ra20actc	7	7	and	and	CC
cord-329515-ra20actc	7	8	the	the	DT
cord-329515-ra20actc	7	9	plasma	plasma	NN
cord-329515-ra20actc	7	10	membrane	membrane	NN
cord-329515-ra20actc	7	11	protein	protein	NN
cord-329515-ra20actc	7	12	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	7	13	IV	IV	NNP
cord-329515-ra20actc	7	14	showed	show	VBD
cord-329515-ra20actc	7	15	that	that	IN
cord-329515-ra20actc	7	16	protein	protein	NN
cord-329515-ra20actc	7	17	sequences	sequence	NNS
cord-329515-ra20actc	7	18	from	from	IN
cord-329515-ra20actc	7	19	all	all	DT
cord-329515-ra20actc	7	20	three	three	CD
cord-329515-ra20actc	7	21	domains	domain	NNS
cord-329515-ra20actc	7	22	of	of	IN
cord-329515-ra20actc	7	23	the	the	DT
cord-329515-ra20actc	7	24	p63	p63	NNP
cord-329515-ra20actc	7	25	protein	protein	NN
cord-329515-ra20actc	7	26	are	be	VBP
cord-329515-ra20actc	7	27	required	require	VBN
cord-329515-ra20actc	7	28	to	to	TO
cord-329515-ra20actc	7	29	achieve	achieve	VB
cord-329515-ra20actc	7	30	complete	complete	JJ
cord-329515-ra20actc	7	31	intracellular	intracellular	JJ
cord-329515-ra20actc	7	32	retention	retention	NN
cord-329515-ra20actc	7	33	.	.	.
cord-329515-ra20actc	8	1	Mutational	mutational	JJ
cord-329515-ra20actc	8	2	analysis	analysis	NN
cord-329515-ra20actc	8	3	of	of	IN
cord-329515-ra20actc	8	4	the	the	DT
cord-329515-ra20actc	8	5	106-amino	106-amino	CD
cord-329515-ra20actc	8	6	acid	acid	NN
cord-329515-ra20actc	8	7	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	8	8	tail	tail	NN
cord-329515-ra20actc	8	9	of	of	IN
cord-329515-ra20actc	8	10	p63	p63	CD
cord-329515-ra20actc	8	11	revealed	reveal	VBD
cord-329515-ra20actc	8	12	that	that	IN
cord-329515-ra20actc	8	13	the	the	DT
cord-329515-ra20actc	8	14	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	8	15	23	23	CD
cord-329515-ra20actc	8	16	amino	amino	NN
cord-329515-ra20actc	8	17	acids	acid	NNS
cord-329515-ra20actc	8	18	are	be	VBP
cord-329515-ra20actc	8	19	necessary	necessary	JJ
cord-329515-ra20actc	8	20	for	for	IN
cord-329515-ra20actc	8	21	retention	retention	NN
cord-329515-ra20actc	8	22	.	.	.
cord-329515-ra20actc	9	1	When	when	WRB
cord-329515-ra20actc	9	2	p63	p63	NNP
cord-329515-ra20actc	9	3	was	be	VBD
cord-329515-ra20actc	9	4	solubilized	solubilize	VBN
cord-329515-ra20actc	9	5	with	with	IN
cord-329515-ra20actc	9	6	Triton	Triton	NNP
cord-329515-ra20actc	9	7	X-100	X-100	NNS
cord-329515-ra20actc	9	8	and	and	CC
cord-329515-ra20actc	9	9	subjected	subject	VBN
cord-329515-ra20actc	9	10	to	to	IN
cord-329515-ra20actc	9	11	centrifugation	centrifugation	NN
cord-329515-ra20actc	9	12	at	at	IN
cord-329515-ra20actc	9	13	100,000	100,000	CD
cord-329515-ra20actc	9	14	g	g	NN
cord-329515-ra20actc	9	15	,	,	,
cord-329515-ra20actc	9	16	it	-PRON-	PRP
cord-329515-ra20actc	9	17	formed	form	VBD
cord-329515-ra20actc	9	18	large	large	JJ
cord-329515-ra20actc	9	19	,	,	,
cord-329515-ra20actc	9	20	insoluble	insoluble	JJ
cord-329515-ra20actc	9	21	oligomers	oligomer	NNS
cord-329515-ra20actc	9	22	,	,	,
cord-329515-ra20actc	9	23	particularly	particularly	RB
cord-329515-ra20actc	9	24	at	at	IN
cord-329515-ra20actc	9	25	neutral	neutral	JJ
cord-329515-ra20actc	9	26	pH	pH	NNP
cord-329515-ra20actc	9	27	and	and	CC
cord-329515-ra20actc	9	28	below	below	RB
cord-329515-ra20actc	9	29	.	.	.
cord-329515-ra20actc	10	1	A	a	DT
cord-329515-ra20actc	10	2	comparison	comparison	NN
cord-329515-ra20actc	10	3	of	of	IN
cord-329515-ra20actc	10	4	the	the	DT
cord-329515-ra20actc	10	5	behavior	behavior	NN
cord-329515-ra20actc	10	6	of	of	IN
cord-329515-ra20actc	10	7	wildtype	wildtype	NN
cord-329515-ra20actc	10	8	and	and	CC
cord-329515-ra20actc	10	9	mutant	mutant	JJ
cord-329515-ra20actc	10	10	p63	p63	CD
cord-329515-ra20actc	10	11	proteins	protein	NNS
cord-329515-ra20actc	10	12	in	in	IN
cord-329515-ra20actc	10	13	this	this	DT
cord-329515-ra20actc	10	14	assay	assay	NN
cord-329515-ra20actc	10	15	revealed	reveal	VBD
cord-329515-ra20actc	10	16	a	a	DT
cord-329515-ra20actc	10	17	perfect	perfect	JJ
cord-329515-ra20actc	10	18	correlation	correlation	NN
cord-329515-ra20actc	10	19	between	between	IN
cord-329515-ra20actc	10	20	the	the	DT
cord-329515-ra20actc	10	21	formation	formation	NN
cord-329515-ra20actc	10	22	of	of	IN
cord-329515-ra20actc	10	23	large	large	JJ
cord-329515-ra20actc	10	24	oligomers	oligomer	NNS
cord-329515-ra20actc	10	25	and	and	CC
cord-329515-ra20actc	10	26	correct	correct	VB
cord-329515-ra20actc	10	27	intracellular	intracellular	JJ
cord-329515-ra20actc	10	28	retention	retention	NN
cord-329515-ra20actc	10	29	.	.	.
cord-329515-ra20actc	11	1	These	these	DT
cord-329515-ra20actc	11	2	results	result	NNS
cord-329515-ra20actc	11	3	suggest	suggest	VBP
cord-329515-ra20actc	11	4	that	that	IN
cord-329515-ra20actc	11	5	self-	self-	NNP
cord-329515-ra20actc	11	6	association	association	NNP
cord-329515-ra20actc	11	7	may	may	MD
cord-329515-ra20actc	11	8	be	be	VB
cord-329515-ra20actc	11	9	a	a	DT
cord-329515-ra20actc	11	10	major	major	JJ
cord-329515-ra20actc	11	11	mechanism	mechanism	NN
cord-329515-ra20actc	11	12	by	by	IN
cord-329515-ra20actc	11	13	which	which	WDT
cord-329515-ra20actc	11	14	p63	p63	NN
cord-329515-ra20actc	11	15	is	be	VBZ
cord-329515-ra20actc	11	16	retained	retain	VBN
cord-329515-ra20actc	11	17	between	between	IN
cord-329515-ra20actc	11	18	the	the	DT
cord-329515-ra20actc	11	19	rough	rough	JJ
cord-329515-ra20actc	11	20	ER	er	NN
cord-329515-ra20actc	11	21	and	and	CC
cord-329515-ra20actc	11	22	the	the	DT
cord-329515-ra20actc	11	23	Golgi	Golgi	NNP
cord-329515-ra20actc	11	24	apparatus	apparatus	NN
cord-329515-ra20actc	11	25	.	.	.
cord-329515-ra20actc	12	1	dent	dent	NNP
cord-329515-ra20actc	12	2	protein	protein	NNP
cord-329515-ra20actc	12	3	of	of	IN
cord-329515-ra20actc	12	4	a	a	DT
cord-329515-ra20actc	12	5	membrane	membrane	NN
cord-329515-ra20actc	12	6	network	network	NN
cord-329515-ra20actc	12	7	interposed	interpose	VBN
cord-329515-ra20actc	12	8	between	between	IN
cord-329515-ra20actc	12	9	rough	rough	JJ
cord-329515-ra20actc	12	10	ER	ER	NNP
cord-329515-ra20actc	12	11	and	and	CC
cord-329515-ra20actc	12	12	Golgi	Golgi	NNP
cord-329515-ra20actc	12	13	apparatus	apparatus	NN
cord-329515-ra20actc	12	14	.	.	.
cord-329515-ra20actc	13	1	To	to	TO
cord-329515-ra20actc	13	2	study	study	VB
cord-329515-ra20actc	13	3	the	the	DT
cord-329515-ra20actc	13	4	retention	retention	NN
cord-329515-ra20actc	13	5	of	of	IN
cord-329515-ra20actc	13	6	p63	p63	CD
cord-329515-ra20actc	13	7	,	,	,
cord-329515-ra20actc	13	8	mutant	mutant	JJ
cord-329515-ra20actc	13	9	forms	form	NNS
cord-329515-ra20actc	13	10	were	be	VBD
cord-329515-ra20actc	13	11	expressed	express	VBN
cord-329515-ra20actc	13	12	in	in	IN
cord-329515-ra20actc	13	13	COS	COS	NNP
cord-329515-ra20actc	13	14	cells	cell	NNS
cord-329515-ra20actc	13	15	and	and	CC
cord-329515-ra20actc	13	16	the	the	DT
cord-329515-ra20actc	13	17	intracellular	intracellular	JJ
cord-329515-ra20actc	13	18	distribution	distribution	NN
cord-329515-ra20actc	13	19	determined	determine	VBN
cord-329515-ra20actc	13	20	by	by	IN
cord-329515-ra20actc	13	21	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	13	22	microscopy	microscopy	NN
cord-329515-ra20actc	13	23	.	.	.
cord-329515-ra20actc	14	1	Investigation	investigation	NN
cord-329515-ra20actc	14	2	of	of	IN
cord-329515-ra20actc	14	3	chimeric	chimeric	JJ
cord-329515-ra20actc	14	4	constructs	construct	NNS
cord-329515-ra20actc	14	5	between	between	IN
cord-329515-ra20actc	14	6	p63	p63	CD
cord-329515-ra20actc	14	7	and	and	CC
cord-329515-ra20actc	14	8	the	the	DT
cord-329515-ra20actc	14	9	plasma	plasma	NN
cord-329515-ra20actc	14	10	membrane	membrane	NN
cord-329515-ra20actc	14	11	protein	protein	NN
cord-329515-ra20actc	14	12	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	14	13	IV	IV	NNP
cord-329515-ra20actc	14	14	showed	show	VBD
cord-329515-ra20actc	14	15	that	that	IN
cord-329515-ra20actc	14	16	protein	protein	NN
cord-329515-ra20actc	14	17	sequences	sequence	NNS
cord-329515-ra20actc	14	18	from	from	IN
cord-329515-ra20actc	14	19	all	all	DT
cord-329515-ra20actc	14	20	three	three	CD
cord-329515-ra20actc	14	21	domains	domain	NNS
cord-329515-ra20actc	14	22	of	of	IN
cord-329515-ra20actc	14	23	the	the	DT
cord-329515-ra20actc	14	24	p63	p63	NNP
cord-329515-ra20actc	14	25	protein	protein	NN
cord-329515-ra20actc	14	26	are	be	VBP
cord-329515-ra20actc	14	27	required	require	VBN
cord-329515-ra20actc	14	28	to	to	TO
cord-329515-ra20actc	14	29	achieve	achieve	VB
cord-329515-ra20actc	14	30	complete	complete	JJ
cord-329515-ra20actc	14	31	intracellular	intracellular	JJ
cord-329515-ra20actc	14	32	retention	retention	NN
cord-329515-ra20actc	14	33	.	.	.
cord-329515-ra20actc	15	1	Mutational	mutational	JJ
cord-329515-ra20actc	15	2	analysis	analysis	NN
cord-329515-ra20actc	15	3	of	of	IN
cord-329515-ra20actc	15	4	the	the	DT
cord-329515-ra20actc	15	5	106-amino	106-amino	CD
cord-329515-ra20actc	15	6	acid	acid	NN
cord-329515-ra20actc	15	7	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	15	8	tail	tail	NN
cord-329515-ra20actc	15	9	of	of	IN
cord-329515-ra20actc	15	10	p63	p63	CD
cord-329515-ra20actc	15	11	revealed	reveal	VBD
cord-329515-ra20actc	15	12	that	that	IN
cord-329515-ra20actc	15	13	the	the	DT
cord-329515-ra20actc	15	14	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	15	15	23	23	CD
cord-329515-ra20actc	15	16	amino	amino	NN
cord-329515-ra20actc	15	17	acids	acid	NNS
cord-329515-ra20actc	15	18	are	be	VBP
cord-329515-ra20actc	15	19	necessary	necessary	JJ
cord-329515-ra20actc	15	20	for	for	IN
cord-329515-ra20actc	15	21	retention	retention	NN
cord-329515-ra20actc	15	22	.	.	.
cord-329515-ra20actc	16	1	When	when	WRB
cord-329515-ra20actc	16	2	Igi3	Igi3	NNP
cord-329515-ra20actc	16	3	was	be	VBD
cord-329515-ra20actc	16	4	solubilized	solubilize	VBN
cord-329515-ra20actc	16	5	with	with	IN
cord-329515-ra20actc	16	6	Triton	Triton	NNP
cord-329515-ra20actc	16	7	X-100	X-100	NNS
cord-329515-ra20actc	16	8	and	and	CC
cord-329515-ra20actc	16	9	subjected	subject	VBN
cord-329515-ra20actc	16	10	to	to	IN
cord-329515-ra20actc	16	11	centrifugation	centrifugation	NN
cord-329515-ra20actc	16	12	at	at	IN
cord-329515-ra20actc	16	13	100,000	100,000	CD
cord-329515-ra20actc	16	14	g	g	NN
cord-329515-ra20actc	16	15	,	,	,
cord-329515-ra20actc	16	16	it	-PRON-	PRP
cord-329515-ra20actc	16	17	formed	form	VBD
cord-329515-ra20actc	16	18	large	large	JJ
cord-329515-ra20actc	16	19	,	,	,
cord-329515-ra20actc	16	20	insoluble	insoluble	JJ
cord-329515-ra20actc	16	21	oligomers	oligomer	NNS
cord-329515-ra20actc	16	22	,	,	,
cord-329515-ra20actc	16	23	particularly	particularly	RB
cord-329515-ra20actc	16	24	at	at	IN
cord-329515-ra20actc	16	25	neutral	neutral	JJ
cord-329515-ra20actc	16	26	pH	pH	NNP
cord-329515-ra20actc	16	27	and	and	CC
cord-329515-ra20actc	16	28	below	below	RB
cord-329515-ra20actc	16	29	.	.	.
cord-329515-ra20actc	17	1	A	a	DT
cord-329515-ra20actc	17	2	comparison	comparison	NN
cord-329515-ra20actc	17	3	of	of	IN
cord-329515-ra20actc	17	4	the	the	DT
cord-329515-ra20actc	17	5	behavior	behavior	NN
cord-329515-ra20actc	17	6	of	of	IN
cord-329515-ra20actc	17	7	wildtype	wildtype	NN
cord-329515-ra20actc	17	8	and	and	CC
cord-329515-ra20actc	17	9	mutant	mutant	JJ
cord-329515-ra20actc	17	10	p63	p63	CD
cord-329515-ra20actc	17	11	proteins	protein	NNS
cord-329515-ra20actc	17	12	in	in	IN
cord-329515-ra20actc	17	13	this	this	DT
cord-329515-ra20actc	17	14	assay	assay	NN
cord-329515-ra20actc	17	15	revealed	reveal	VBD
cord-329515-ra20actc	17	16	a	a	DT
cord-329515-ra20actc	17	17	perfect	perfect	JJ
cord-329515-ra20actc	17	18	correlation	correlation	NN
cord-329515-ra20actc	17	19	between	between	IN
cord-329515-ra20actc	17	20	the	the	DT
cord-329515-ra20actc	17	21	formation	formation	NN
cord-329515-ra20actc	17	22	of	of	IN
cord-329515-ra20actc	17	23	large	large	JJ
cord-329515-ra20actc	17	24	oligomers	oligomer	NNS
cord-329515-ra20actc	17	25	and	and	CC
cord-329515-ra20actc	17	26	correct	correct	VB
cord-329515-ra20actc	17	27	intracellular	intracellular	JJ
cord-329515-ra20actc	17	28	retention	retention	NN
cord-329515-ra20actc	17	29	.	.	.
cord-329515-ra20actc	18	1	These	these	DT
cord-329515-ra20actc	18	2	results	result	NNS
cord-329515-ra20actc	18	3	suggest	suggest	VBP
cord-329515-ra20actc	18	4	that	that	IN
cord-329515-ra20actc	18	5	self	self	NN
cord-329515-ra20actc	18	6	-	-	HYPH
cord-329515-ra20actc	18	7	association	association	NN
cord-329515-ra20actc	18	8	may	may	MD
cord-329515-ra20actc	18	9	be	be	VB
cord-329515-ra20actc	18	10	a	a	DT
cord-329515-ra20actc	18	11	major	major	JJ
cord-329515-ra20actc	18	12	mechanism	mechanism	NN
cord-329515-ra20actc	18	13	by	by	IN
cord-329515-ra20actc	18	14	which	which	WDT
cord-329515-ra20actc	18	15	p63	p63	NN
cord-329515-ra20actc	18	16	is	be	VBZ
cord-329515-ra20actc	18	17	retained	retain	VBN
cord-329515-ra20actc	18	18	between	between	IN
cord-329515-ra20actc	18	19	the	the	DT
cord-329515-ra20actc	18	20	rough	rough	JJ
cord-329515-ra20actc	18	21	ER	er	NN
cord-329515-ra20actc	18	22	and	and	CC
cord-329515-ra20actc	18	23	the	the	DT
cord-329515-ra20actc	18	24	Golgi	Golgi	NNP
cord-329515-ra20actc	18	25	apparatus	apparatus	NN
cord-329515-ra20actc	18	26	.	.	.
cord-329515-ra20actc	19	1	T	T	NNP
cord-329515-ra20actc	19	2	HE	HE	NNP
cord-329515-ra20actc	19	3	Secretory	secretory	JJ
cord-329515-ra20actc	19	4	pathway	pathway	NN
cord-329515-ra20actc	19	5	of	of	IN
cord-329515-ra20actc	19	6	eukaryotic	eukaryotic	JJ
cord-329515-ra20actc	19	7	cells	cell	NNS
cord-329515-ra20actc	19	8	is	be	VBZ
cord-329515-ra20actc	19	9	composed	compose	VBN
cord-329515-ra20actc	19	10	of	of	IN
cord-329515-ra20actc	19	11	a	a	DT
cord-329515-ra20actc	19	12	series	series	NN
cord-329515-ra20actc	19	13	of	of	IN
cord-329515-ra20actc	19	14	different	different	JJ
cord-329515-ra20actc	19	15	compartments	compartment	NNS
cord-329515-ra20actc	19	16	through	through	IN
cord-329515-ra20actc	19	17	which	which	WDT
cord-329515-ra20actc	19	18	newly	newly	RB
cord-329515-ra20actc	19	19	synthesized	synthesize	VBN
cord-329515-ra20actc	19	20	proteins	protein	NNS
cord-329515-ra20actc	19	21	are	be	VBP
cord-329515-ra20actc	19	22	transported	transport	VBN
cord-329515-ra20actc	19	23	en	en	IN
cord-329515-ra20actc	19	24	route	route	NN
cord-329515-ra20actc	19	25	to	to	IN
cord-329515-ra20actc	19	26	their	-PRON-	PRP$
cord-329515-ra20actc	19	27	final	final	JJ
cord-329515-ra20actc	19	28	destination	destination	NN
cord-329515-ra20actc	19	29	in	in	IN
cord-329515-ra20actc	19	30	the	the	DT
cord-329515-ra20actc	19	31	cell	cell	NN
cord-329515-ra20actc	19	32	(	(	-LRB-
cord-329515-ra20actc	19	33	Paiade	Paiade	NNP
cord-329515-ra20actc	19	34	,	,	,
cord-329515-ra20actc	19	35	1975	1975	CD
cord-329515-ra20actc	19	36	)	)	-RRB-
cord-329515-ra20actc	19	37	.	.	.
cord-329515-ra20actc	20	1	Each	each	DT
cord-329515-ra20actc	20	2	of	of	IN
cord-329515-ra20actc	20	3	the	the	DT
cord-329515-ra20actc	20	4	subcellular	subcellular	JJ
cord-329515-ra20actc	20	5	organelles	organelle	NNS
cord-329515-ra20actc	20	6	along	along	IN
cord-329515-ra20actc	20	7	this	this	DT
cord-329515-ra20actc	20	8	pathway	pathway	NN
cord-329515-ra20actc	20	9	contains	contain	VBZ
cord-329515-ra20actc	20	10	a	a	DT
cord-329515-ra20actc	20	11	characteristic	characteristic	JJ
cord-329515-ra20actc	20	12	set	set	NN
cord-329515-ra20actc	20	13	of	of	IN
cord-329515-ra20actc	20	14	proteins	protein	NNS
cord-329515-ra20actc	20	15	that	that	WDT
cord-329515-ra20actc	20	16	maintain	maintain	VBP
cord-329515-ra20actc	20	17	their	-PRON-	PRP$
cord-329515-ra20actc	20	18	structural	structural	JJ
cord-329515-ra20actc	20	19	and	and	CC
cord-329515-ra20actc	20	20	functionai	functionai	JJ
cord-329515-ra20actc	20	21	integrity	integrity	NN
cord-329515-ra20actc	20	22	.	.	.
cord-329515-ra20actc	21	1	A	a	DT
cord-329515-ra20actc	21	2	challenging	challenging	JJ
cord-329515-ra20actc	21	3	question	question	NN
cord-329515-ra20actc	21	4	in	in	IN
cord-329515-ra20actc	21	5	contemporary	contemporary	JJ
cord-329515-ra20actc	21	6	cell	cell	NN
cord-329515-ra20actc	21	7	biology	biology	NN
cord-329515-ra20actc	21	8	is	be	VBZ
cord-329515-ra20actc	21	9	to	to	TO
cord-329515-ra20actc	21	10	understand	understand	VB
cord-329515-ra20actc	21	11	how	how	WRB
cord-329515-ra20actc	21	12	resident	resident	JJ
cord-329515-ra20actc	21	13	components	component	NNS
cord-329515-ra20actc	21	14	,	,	,
cord-329515-ra20actc	21	15	unlike	unlike	IN
cord-329515-ra20actc	21	16	itinerant	itinerant	JJ
cord-329515-ra20actc	21	17	proteins	protein	NNS
cord-329515-ra20actc	21	18	,	,	,
cord-329515-ra20actc	21	19	achieve	achieve	VBP
cord-329515-ra20actc	21	20	specific	specific	JJ
cord-329515-ra20actc	21	21	localization	localization	NN
cord-329515-ra20actc	21	22	in	in	IN
cord-329515-ra20actc	21	23	a	a	DT
cord-329515-ra20actc	21	24	given	give	VBN
cord-329515-ra20actc	21	25	intracellular	intracellular	JJ
cord-329515-ra20actc	21	26	compartment	compartment	NN
cord-329515-ra20actc	21	27	.	.	.
cord-329515-ra20actc	22	1	It	-PRON-	PRP
cord-329515-ra20actc	22	2	is	be	VBZ
cord-329515-ra20actc	22	3	currently	currently	RB
cord-329515-ra20actc	22	4	believed	believe	VBN
cord-329515-ra20actc	22	5	that	that	IN
cord-329515-ra20actc	22	6	secretory	secretory	JJ
cord-329515-ra20actc	22	7	proteins	protein	NNS
cord-329515-ra20actc	22	8	are	be	VBP
cord-329515-ra20actc	22	9	transported	transport	VBN
cord-329515-ra20actc	22	10	by	by	IN
cord-329515-ra20actc	22	11	a	a	DT
cord-329515-ra20actc	22	12	default	default	NN
cord-329515-ra20actc	22	13	pathway	pathway	NN
cord-329515-ra20actc	22	14	while	while	IN
cord-329515-ra20actc	22	15	resident	resident	JJ
cord-329515-ra20actc	22	16	proteins	protein	NNS
cord-329515-ra20actc	22	17	are	be	VBP
cord-329515-ra20actc	22	18	selectively	selectively	RB
cord-329515-ra20actc	22	19	retained	retain	VBN
cord-329515-ra20actc	22	20	in	in	IN
cord-329515-ra20actc	22	21	individual	individual	JJ
cord-329515-ra20actc	22	22	organelles	organelle	NNS
cord-329515-ra20actc	22	23	by	by	IN
cord-329515-ra20actc	22	24	means	mean	NNS
cord-329515-ra20actc	22	25	of	of	IN
cord-329515-ra20actc	22	26	specific	specific	JJ
cord-329515-ra20actc	22	27	signals	signal	NNS
cord-329515-ra20actc	22	28	(	(	-LRB-
cord-329515-ra20actc	22	29	Pfeffer	Pfeffer	NNP
cord-329515-ra20actc	22	30	and	and	CC
cord-329515-ra20actc	22	31	Rothman	Rothman	NNP
cord-329515-ra20actc	22	32	,	,	,
cord-329515-ra20actc	22	33	1987	1987	CD
cord-329515-ra20actc	22	34	;	;	:
cord-329515-ra20actc	22	35	Wieland	Wieland	NNP
cord-329515-ra20actc	22	36	et	et	NNP
cord-329515-ra20actc	22	37	al	al	NNP
cord-329515-ra20actc	22	38	.	.	NNP
cord-329515-ra20actc	22	39	,	,	,
cord-329515-ra20actc	22	40	1987	1987	CD
cord-329515-ra20actc	22	41	;	;	:
cord-329515-ra20actc	22	42	Karrenbauer	Karrenbauer	NNP
cord-329515-ra20actc	22	43	et	et	NNP
cord-329515-ra20actc	22	44	al	al	NNP
cord-329515-ra20actc	22	45	.	.	NNP
cord-329515-ra20actc	22	46	,	,	,
cord-329515-ra20actc	22	47	1990	1990	CD
cord-329515-ra20actc	22	48	)	)	-RRB-
cord-329515-ra20actc	22	49	.	.	.
cord-329515-ra20actc	23	1	Two	two	CD
cord-329515-ra20actc	23	2	types	type	NNS
cord-329515-ra20actc	23	3	of	of	IN
cord-329515-ra20actc	23	4	signais	signais	NNP
cord-329515-ra20actc	23	5	,	,	,
cord-329515-ra20actc	23	6	which	which	WDT
cord-329515-ra20actc	23	7	mediate	mediate	VBP
cord-329515-ra20actc	23	8	either	either	CC
cord-329515-ra20actc	23	9	the	the	DT
cord-329515-ra20actc	23	10	retention	retention	NN
cord-329515-ra20actc	23	11	or	or	CC
cord-329515-ra20actc	23	12	the	the	DT
cord-329515-ra20actc	23	13	retrieval	retrieval	NN
cord-329515-ra20actc	23	14	of	of	IN
cord-329515-ra20actc	23	15	proteins	protein	NNS
cord-329515-ra20actc	23	16	,	,	,
cord-329515-ra20actc	23	17	have	have	VBP
cord-329515-ra20actc	23	18	been	be	VBN
cord-329515-ra20actc	23	19	identified	identify	VBN
cord-329515-ra20actc	23	20	to	to	IN
cord-329515-ra20actc	23	21	date	date	NN
cord-329515-ra20actc	23	22	.	.	.
cord-329515-ra20actc	24	1	A	a	DT
cord-329515-ra20actc	24	2	variety	variety	NN
cord-329515-ra20actc	24	3	of	of	IN
cord-329515-ra20actc	24	4	lumenal	lumenal	JJ
cord-329515-ra20actc	24	5	ER	ER	NNP
cord-329515-ra20actc	24	6	proteins	protein	NNS
cord-329515-ra20actc	24	7	are	be	VBP
cord-329515-ra20actc	24	8	retained	retain	VBN
cord-329515-ra20actc	24	9	in	in	IN
cord-329515-ra20actc	24	10	the	the	DT
cord-329515-ra20actc	24	11	cell	cell	NN
cord-329515-ra20actc	24	12	by	by	IN
cord-329515-ra20actc	24	13	means	mean	NNS
cord-329515-ra20actc	24	14	of	of	IN
cord-329515-ra20actc	24	15	a	a	DT
cord-329515-ra20actc	24	16	COOH	COOH	NNP
cord-329515-ra20actc	24	17	-	-	HYPH
cord-329515-ra20actc	24	18	terminal	terminal	NN
cord-329515-ra20actc	24	19	tetrapeptide	tetrapeptide	NN
cord-329515-ra20actc	24	20	(	(	-LRB-
cord-329515-ra20actc	24	21	KDEL	KDEL	NNP
cord-329515-ra20actc	24	22	)	)	-RRB-
cord-329515-ra20actc	24	23	or	or	CC
cord-329515-ra20actc	24	24	related	related	JJ
cord-329515-ra20actc	24	25	sequence	sequence	NN
cord-329515-ra20actc	24	26	(	(	-LRB-
cord-329515-ra20actc	24	27	Munro	Munro	NNP
cord-329515-ra20actc	24	28	and	and	CC
cord-329515-ra20actc	24	29	Pelham	Pelham	NNP
cord-329515-ra20actc	24	30	,	,	,
cord-329515-ra20actc	24	31	1987	1987	CD
cord-329515-ra20actc	24	32	;	;	:
cord-329515-ra20actc	24	33	 	 	_SP
cord-329515-ra20actc	24	34	reviewed	review	VBN
cord-329515-ra20actc	24	35	by	by	IN
cord-329515-ra20actc	24	36	Pelham	Pelham	NNP
cord-329515-ra20actc	24	37	,	,	,
cord-329515-ra20actc	24	38	1989	1989	CD
cord-329515-ra20actc	24	39	Pelham	Pelham	NNP
cord-329515-ra20actc	24	40	,	,	,
cord-329515-ra20actc	24	41	,	,	,
cord-329515-ra20actc	24	42	1990	1990	CD
cord-329515-ra20actc	24	43	)	)	-RRB-
cord-329515-ra20actc	24	44	that	that	WDT
cord-329515-ra20actc	24	45	allows	allow	VBZ
cord-329515-ra20actc	24	46	retrievai	retrievai	NN
cord-329515-ra20actc	24	47	of	of	IN
cord-329515-ra20actc	24	48	the	the	DT
cord-329515-ra20actc	24	49	proteins	protein	NNS
cord-329515-ra20actc	24	50	from	from	IN
cord-329515-ra20actc	24	51	a	a	DT
cord-329515-ra20actc	24	52	post	post	JJ
cord-329515-ra20actc	24	53	-	-	JJ
cord-329515-ra20actc	24	54	ER	er	JJ
cord-329515-ra20actc	24	55	site	site	NN
cord-329515-ra20actc	24	56	by	by	IN
cord-329515-ra20actc	24	57	means	mean	NNS
cord-329515-ra20actc	24	58	of	of	IN
cord-329515-ra20actc	24	59	KDEL	KDEL	NNP
cord-329515-ra20actc	24	60	receptors	receptor	NNS
cord-329515-ra20actc	24	61	Pelham	Pelham	NNP
cord-329515-ra20actc	24	62	,	,	,
cord-329515-ra20actc	24	63	1990	1990	CD
cord-329515-ra20actc	24	64	,	,	,
cord-329515-ra20actc	24	65	1992	1992	CD
cord-329515-ra20actc	24	66	)	)	-RRB-
cord-329515-ra20actc	24	67	.	.	.
cord-329515-ra20actc	25	1	A	a	DT
cord-329515-ra20actc	25	2	group	group	NN
cord-329515-ra20actc	25	3	of	of	IN
cord-329515-ra20actc	25	4	type	type	NN
cord-329515-ra20actc	25	5	I	-PRON-	PRP
cord-329515-ra20actc	25	6	transmembrane	transmembrane	NN
cord-329515-ra20actc	25	7	proteins	protein	NNS
cord-329515-ra20actc	25	8	of	of	IN
cord-329515-ra20actc	25	9	the	the	DT
cord-329515-ra20actc	25	10	ER	ER	NNP
cord-329515-ra20actc	25	11	are	be	VBP
cord-329515-ra20actc	25	12	also	also	RB
cord-329515-ra20actc	25	13	retained	retain	VBN
cord-329515-ra20actc	25	14	in	in	IN
cord-329515-ra20actc	25	15	this	this	DT
cord-329515-ra20actc	25	16	or	or	CC
cord-329515-ra20actc	25	17	-	-	HYPH
cord-329515-ra20actc	25	18	ganelle	ganelle	NN
cord-329515-ra20actc	25	19	by	by	IN
cord-329515-ra20actc	25	20	a	a	DT
cord-329515-ra20actc	25	21	retrieval	retrieval	NN
cord-329515-ra20actc	25	22	mechanism	mechanism	NN
cord-329515-ra20actc	25	23	(	(	-LRB-
cord-329515-ra20actc	25	24	Jackson	Jackson	NNP
cord-329515-ra20actc	25	25	et	et	NNP
cord-329515-ra20actc	25	26	al	al	NNP
cord-329515-ra20actc	25	27	.	.	NNP
cord-329515-ra20actc	25	28	,	,	,
cord-329515-ra20actc	25	29	1993	1993	CD
cord-329515-ra20actc	25	30	)	)	-RRB-
cord-329515-ra20actc	25	31	.	.	.
cord-329515-ra20actc	26	1	These	these	DT
cord-329515-ra20actc	26	2	proteins	protein	NNS
cord-329515-ra20actc	26	3	contain	contain	VBP
cord-329515-ra20actc	26	4	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	26	5	sequences	sequence	NNS
cord-329515-ra20actc	26	6	consisting	consist	VBG
cord-329515-ra20actc	26	7	of	of	IN
cord-329515-ra20actc	26	8	two	two	CD
cord-329515-ra20actc	26	9	lysine	lysine	NN
cord-329515-ra20actc	26	10	residues	residue	NNS
cord-329515-ra20actc	26	11	positioned	position	VBD
cord-329515-ra20actc	26	12	three	three	CD
cord-329515-ra20actc	26	13	and	and	CC
cord-329515-ra20actc	26	14	four	four	CD
cord-329515-ra20actc	26	15	or	or	CC
cord-329515-ra20actc	26	16	five	five	CD
cord-329515-ra20actc	26	17	residues	residue	NNS
cord-329515-ra20actc	26	18	from	from	IN
cord-329515-ra20actc	26	19	the	the	DT
cord-329515-ra20actc	26	20	COOH	COOH	NNP
cord-329515-ra20actc	26	21	terminus	terminus	NN
cord-329515-ra20actc	26	22	(	(	-LRB-
cord-329515-ra20actc	26	23	KKXX	KKXX	NNP
cord-329515-ra20actc	26	24	or	or	CC
cord-329515-ra20actc	26	25	KXKXX	KXKXX	NNP
cord-329515-ra20actc	26	26	,	,	,
cord-329515-ra20actc	26	27	where	where	WRB
cord-329515-ra20actc	26	28	X	x	NN
cord-329515-ra20actc	26	29	can	can	MD
cord-329515-ra20actc	26	30	be	be	VB
cord-329515-ra20actc	26	31	almost	almost	RB
cord-329515-ra20actc	26	32	any	any	DT
cord-329515-ra20actc	26	33	amino	amino	NN
cord-329515-ra20actc	26	34	acid	acid	NN
cord-329515-ra20actc	26	35	)	)	-RRB-
cord-329515-ra20actc	27	1	(	(	-LRB-
cord-329515-ra20actc	27	2	Jackson	Jackson	NNP
cord-329515-ra20actc	27	3	et	et	NNP
cord-329515-ra20actc	27	4	ai	ai	NNP
cord-329515-ra20actc	27	5	.	.	NNP
cord-329515-ra20actc	27	6	,	,	,
cord-329515-ra20actc	27	7	1990	1990	CD
cord-329515-ra20actc	27	8	;	;	:
cord-329515-ra20actc	27	9	Shin	Shin	NNP
cord-329515-ra20actc	27	10	et	et	NNP
cord-329515-ra20actc	27	11	ai	ai	NNP
cord-329515-ra20actc	27	12	.	.	NNP
cord-329515-ra20actc	27	13	,	,	,
cord-329515-ra20actc	27	14	1991	1991	CD
cord-329515-ra20actc	27	15	)	)	-RRB-
cord-329515-ra20actc	27	16	.	.	.
cord-329515-ra20actc	28	1	Recycling	recycling	NN
cord-329515-ra20actc	28	2	of	of	IN
cord-329515-ra20actc	28	3	these	these	DT
cord-329515-ra20actc	28	4	proteins	protein	NNS
cord-329515-ra20actc	28	5	is	be	VBZ
cord-329515-ra20actc	28	6	believed	believe	VBN
cord-329515-ra20actc	28	7	to	to	TO
cord-329515-ra20actc	28	8	occur	occur	VB
cord-329515-ra20actc	28	9	from	from	IN
cord-329515-ra20actc	28	10	multiple	multiple	JJ
cord-329515-ra20actc	28	11	post	post	JJ
cord-329515-ra20actc	28	12	-	-	JJ
cord-329515-ra20actc	28	13	ER	er	JJ
cord-329515-ra20actc	28	14	locations	location	NNS
cord-329515-ra20actc	28	15	along	along	IN
cord-329515-ra20actc	28	16	the	the	DT
cord-329515-ra20actc	28	17	secretory	secretory	JJ
cord-329515-ra20actc	28	18	pathway	pathway	NN
cord-329515-ra20actc	29	1	(	(	-LRB-
cord-329515-ra20actc	29	2	Jackson	Jackson	NNP
cord-329515-ra20actc	29	3	et	et	NNP
cord-329515-ra20actc	29	4	ai	ai	NNP
cord-329515-ra20actc	29	5	.	.	NNP
cord-329515-ra20actc	29	6	,	,	,
cord-329515-ra20actc	29	7	1993	1993	CD
cord-329515-ra20actc	29	8	)	)	-RRB-
cord-329515-ra20actc	29	9	.	.	.
cord-329515-ra20actc	30	1	In	in	IN
cord-329515-ra20actc	30	2	addition	addition	NN
cord-329515-ra20actc	30	3	,	,	,
cord-329515-ra20actc	30	4	retrieval	retrieval	NN
cord-329515-ra20actc	30	5	has	have	VBZ
cord-329515-ra20actc	30	6	been	be	VBN
cord-329515-ra20actc	30	7	suggested	suggest	VBN
cord-329515-ra20actc	30	8	to	to	TO
cord-329515-ra20actc	30	9	be	be	VB
cord-329515-ra20actc	30	10	the	the	DT
cord-329515-ra20actc	30	11	mechanism	mechanism	NN
cord-329515-ra20actc	30	12	by	by	IN
cord-329515-ra20actc	30	13	which	which	WDT
cord-329515-ra20actc	30	14	the	the	DT
cord-329515-ra20actc	30	15	integral	integral	JJ
cord-329515-ra20actc	30	16	membrane	membrane	NN
cord-329515-ra20actc	30	17	protein	protein	NN
cord-329515-ra20actc	30	18	TGN38	TGN38	NNP
cord-329515-ra20actc	30	19	is	be	VBZ
cord-329515-ra20actc	30	20	targeted	target	VBN
cord-329515-ra20actc	30	21	to	to	IN
cord-329515-ra20actc	30	22	the	the	DT
cord-329515-ra20actc	30	23	TGN	TGN	NNP
cord-329515-ra20actc	31	1	(	(	-LRB-
cord-329515-ra20actc	31	2	Bos	Bos	NNP
cord-329515-ra20actc	31	3	et	et	NNP
cord-329515-ra20actc	31	4	ai	ai	NNP
cord-329515-ra20actc	31	5	.	.	NNP
cord-329515-ra20actc	31	6	,	,	,
cord-329515-ra20actc	31	7	1993	1993	CD
cord-329515-ra20actc	31	8	;	;	:
cord-329515-ra20actc	31	9	Humphrey	Humphrey	NNP
cord-329515-ra20actc	31	10	et	et	NNP
cord-329515-ra20actc	31	11	al	al	NNP
cord-329515-ra20actc	31	12	.	.	NNP
cord-329515-ra20actc	31	13	,	,	,
cord-329515-ra20actc	31	14	1993	1993	CD
cord-329515-ra20actc	31	15	)	)	-RRB-
cord-329515-ra20actc	31	16	.	.	.
cord-329515-ra20actc	32	1	TGN38	TGN38	NNP
cord-329515-ra20actc	32	2	possesses	possess	VBZ
cord-329515-ra20actc	32	3	a	a	DT
cord-329515-ra20actc	32	4	tyrosine	tyrosine	NN
cord-329515-ra20actc	32	5	-	-	HYPH
cord-329515-ra20actc	32	6	containing	contain	VBG
cord-329515-ra20actc	32	7	motif	motif	NN
cord-329515-ra20actc	32	8	within	within	IN
cord-329515-ra20actc	32	9	its	-PRON-	PRP$
cord-329515-ra20actc	32	10	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	32	11	tail	tail	NN
cord-329515-ra20actc	32	12	that	that	WDT
cord-329515-ra20actc	32	13	is	be	VBZ
cord-329515-ra20actc	32	14	both	both	DT
cord-329515-ra20actc	32	15	necessary	necessary	JJ
cord-329515-ra20actc	32	16	and	and	CC
cord-329515-ra20actc	32	17	sufficient	sufficient	JJ
cord-329515-ra20actc	32	18	for	for	IN
cord-329515-ra20actc	32	19	TGN	TGN	NNP
cord-329515-ra20actc	32	20	localization	localization	NN
cord-329515-ra20actc	33	1	(	(	-LRB-
cord-329515-ra20actc	33	2	Bos	Bos	NNP
cord-329515-ra20actc	33	3	et	et	NNP
cord-329515-ra20actc	33	4	ai	ai	NNP
cord-329515-ra20actc	33	5	.	.	NNP
cord-329515-ra20actc	33	6	,	,	,
cord-329515-ra20actc	33	7	1993	1993	CD
cord-329515-ra20actc	33	8	;	;	:
cord-329515-ra20actc	33	9	Humphrey	Humphrey	NNP
cord-329515-ra20actc	33	10	et	et	NNP
cord-329515-ra20actc	33	11	ai	ai	NNP
cord-329515-ra20actc	33	12	.	.	NNP
cord-329515-ra20actc	33	13	,	,	,
cord-329515-ra20actc	33	14	1993	1993	CD
cord-329515-ra20actc	33	15	;	;	:
cord-329515-ra20actc	33	16	Wong	Wong	NNP
cord-329515-ra20actc	33	17	and	and	CC
cord-329515-ra20actc	33	18	Hong	Hong	NNP
cord-329515-ra20actc	33	19	,	,	,
cord-329515-ra20actc	33	20	1993	1993	CD
cord-329515-ra20actc	33	21	)	)	-RRB-
cord-329515-ra20actc	33	22	.	.	.
cord-329515-ra20actc	34	1	In	in	IN
cord-329515-ra20actc	34	2	contrast	contrast	NN
cord-329515-ra20actc	34	3	to	to	IN
cord-329515-ra20actc	34	4	these	these	DT
cord-329515-ra20actc	34	5	examples	example	NNS
cord-329515-ra20actc	34	6	,	,	,
cord-329515-ra20actc	34	7	localization	localization	NN
cord-329515-ra20actc	34	8	of	of	IN
cord-329515-ra20actc	34	9	Golgi	Golgi	NNP
cord-329515-ra20actc	34	10	proteins	protein	NNS
cord-329515-ra20actc	34	11	is	be	VBZ
cord-329515-ra20actc	34	12	achieved	achieve	VBN
cord-329515-ra20actc	34	13	by	by	IN
cord-329515-ra20actc	34	14	retention	retention	NN
cord-329515-ra20actc	34	15	rather	rather	RB
cord-329515-ra20actc	34	16	than	than	IN
cord-329515-ra20actc	34	17	retrieval	retrieval	NN
cord-329515-ra20actc	34	18	.	.	.
cord-329515-ra20actc	35	1	The	the	DT
cord-329515-ra20actc	35	2	retention	retention	NN
cord-329515-ra20actc	35	3	of	of	IN
cord-329515-ra20actc	35	4	several	several	JJ
cord-329515-ra20actc	35	5	Golgi	Golgi	NNP
cord-329515-ra20actc	35	6	proteins	protein	NNS
cord-329515-ra20actc	35	7	has	have	VBZ
cord-329515-ra20actc	35	8	been	be	VBN
cord-329515-ra20actc	35	9	shown	show	VBN
cord-329515-ra20actc	35	10	to	to	TO
cord-329515-ra20actc	35	11	depend	depend	VB
cord-329515-ra20actc	35	12	primarily	primarily	RB
cord-329515-ra20actc	35	13	on	on	IN
cord-329515-ra20actc	35	14	their	-PRON-	PRP$
cord-329515-ra20actc	35	15	single	single	JJ
cord-329515-ra20actc	35	16	transmembrane	transmembrane	NN
cord-329515-ra20actc	35	17	segment	segment	NN
cord-329515-ra20actc	35	18	with	with	IN
cord-329515-ra20actc	35	19	some	some	DT
cord-329515-ra20actc	35	20	additional	additional	JJ
cord-329515-ra20actc	35	21	contribution	contribution	NN
cord-329515-ra20actc	35	22	to	to	IN
cord-329515-ra20actc	35	23	retention	retention	NN
cord-329515-ra20actc	35	24	by	by	IN
cord-329515-ra20actc	35	25	the	the	DT
cord-329515-ra20actc	35	26	sequences	sequence	NNS
cord-329515-ra20actc	35	27	just	just	RB
cord-329515-ra20actc	35	28	adjacent	adjacent	JJ
cord-329515-ra20actc	35	29	to	to	IN
cord-329515-ra20actc	35	30	those	those	DT
cord-329515-ra20actc	35	31	membrane	membrane	NN
cord-329515-ra20actc	35	32	anchors	anchor	NNS
cord-329515-ra20actc	36	1	(	(	-LRB-
cord-329515-ra20actc	36	2	Nilsson	Nilsson	NNP
cord-329515-ra20actc	36	3	et	et	NNP
cord-329515-ra20actc	36	4	ai	ai	NNP
cord-329515-ra20actc	36	5	.	.	NNP
cord-329515-ra20actc	36	6	,	,	,
cord-329515-ra20actc	36	7	1991	1991	CD
cord-329515-ra20actc	36	8	;	;	:
cord-329515-ra20actc	37	1	Swift	Swift	NNP
cord-329515-ra20actc	37	2	and	and	CC
cord-329515-ra20actc	37	3	Machamer	Machamer	NNP
cord-329515-ra20actc	37	4	,	,	,
cord-329515-ra20actc	37	5	1991	1991	CD
cord-329515-ra20actc	37	6	;	;	:
cord-329515-ra20actc	37	7	Machamer	Machamer	NNP
cord-329515-ra20actc	37	8	et	et	NNP
cord-329515-ra20actc	37	9	al	al	NNP
cord-329515-ra20actc	37	10	.	.	NNP
cord-329515-ra20actc	37	11	,	,	,
cord-329515-ra20actc	37	12	1993	1993	CD
cord-329515-ra20actc	37	13	)	)	-RRB-
cord-329515-ra20actc	37	14	.	.	.
cord-329515-ra20actc	38	1	In	in	IN
cord-329515-ra20actc	38	2	the	the	DT
cord-329515-ra20actc	38	3	case	case	NN
cord-329515-ra20actc	38	4	of	of	IN
cord-329515-ra20actc	38	5	the	the	DT
cord-329515-ra20actc	38	6	c~	c~	NNP
cord-329515-ra20actc	38	7	2,6-siaiyltransferase	2,6-siaiyltransferase	CD
cord-329515-ra20actc	38	8	,	,	,
cord-329515-ra20actc	38	9	the	the	DT
cord-329515-ra20actc	38	10	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	38	11	and	and	CC
cord-329515-ra20actc	38	12	lumenal	lumenal	JJ
cord-329515-ra20actc	38	13	sequences	sequence	NNS
cord-329515-ra20actc	38	14	flanking	flank	VBG
cord-329515-ra20actc	38	15	the	the	DT
cord-329515-ra20actc	38	16	transmembrane	transmembrane	NNP
cord-329515-ra20actc	38	17	segment	segment	NN
cord-329515-ra20actc	38	18	appear	appear	VBP
cord-329515-ra20actc	38	19	to	to	TO
cord-329515-ra20actc	38	20	be	be	VB
cord-329515-ra20actc	38	21	the	the	DT
cord-329515-ra20actc	38	22	crucial	crucial	JJ
cord-329515-ra20actc	38	23	elements	element	NNS
cord-329515-ra20actc	38	24	for	for	IN
cord-329515-ra20actc	38	25	retention	retention	NN
cord-329515-ra20actc	38	26	rather	rather	RB
cord-329515-ra20actc	38	27	than	than	IN
cord-329515-ra20actc	38	28	the	the	DT
cord-329515-ra20actc	38	29	transmembrane	transmembrane	NN
cord-329515-ra20actc	38	30	segment	segment	NN
cord-329515-ra20actc	38	31	itself	-PRON-	PRP
cord-329515-ra20actc	38	32	(	(	-LRB-
cord-329515-ra20actc	38	33	Munro	Munro	NNP
cord-329515-ra20actc	38	34	,	,	,
cord-329515-ra20actc	38	35	1991	1991	CD
cord-329515-ra20actc	38	36	;	;	:
cord-329515-ra20actc	38	37	Dahdal	Dahdal	NNP
cord-329515-ra20actc	38	38	and	and	CC
cord-329515-ra20actc	38	39	Colley	Colley	NNP
cord-329515-ra20actc	38	40	,	,	,
cord-329515-ra20actc	38	41	1993	1993	CD
cord-329515-ra20actc	38	42	)	)	-RRB-
cord-329515-ra20actc	38	43	.	.	.
cord-329515-ra20actc	39	1	It	-PRON-	PRP
cord-329515-ra20actc	39	2	has	have	VBZ
cord-329515-ra20actc	39	3	been	be	VBN
cord-329515-ra20actc	39	4	postulated	postulate	VBN
cord-329515-ra20actc	39	5	that	that	IN
cord-329515-ra20actc	39	6	resident	resident	JJ
cord-329515-ra20actc	39	7	Golgi	Golgi	NNP
cord-329515-ra20actc	39	8	proteins	protein	NNS
cord-329515-ra20actc	39	9	oligomerize	oligomerize	NN
cord-329515-ra20actc	39	10	in	in	IN
cord-329515-ra20actc	39	11	the	the	DT
cord-329515-ra20actc	39	12	Golgi	Golgi	NNP
cord-329515-ra20actc	39	13	apparatus	apparatus	NN
cord-329515-ra20actc	39	14	upon	upon	IN
cord-329515-ra20actc	39	15	recognition	recognition	NN
cord-329515-ra20actc	39	16	of	of	IN
cord-329515-ra20actc	39	17	identical	identical	JJ
cord-329515-ra20actc	39	18	or	or	CC
cord-329515-ra20actc	39	19	related	related	JJ
cord-329515-ra20actc	39	20	proteins	protein	NNS
cord-329515-ra20actc	39	21	,	,	,
cord-329515-ra20actc	39	22	forming	form	VBG
cord-329515-ra20actc	39	23	a	a	DT
cord-329515-ra20actc	39	24	complex	complex	NN
cord-329515-ra20actc	39	25	of	of	IN
cord-329515-ra20actc	39	26	sufficient	sufficient	JJ
cord-329515-ra20actc	39	27	size	size	NN
cord-329515-ra20actc	39	28	to	to	TO
cord-329515-ra20actc	39	29	prevent	prevent	VB
cord-329515-ra20actc	39	30	entry	entry	NN
cord-329515-ra20actc	39	31	into	into	IN
cord-329515-ra20actc	39	32	transport	transport	NN
cord-329515-ra20actc	39	33	vesicles	vesicle	NNS
cord-329515-ra20actc	39	34	(	(	-LRB-
cord-329515-ra20actc	39	35	Machamer	Machamer	NNP
cord-329515-ra20actc	39	36	,	,	,
cord-329515-ra20actc	39	37	1991	1991	CD
cord-329515-ra20actc	39	38	;	;	:
cord-329515-ra20actc	39	39	Nilsson	Nilsson	NNP
cord-329515-ra20actc	39	40	et	et	NNP
cord-329515-ra20actc	39	41	al	al	NNP
cord-329515-ra20actc	39	42	.	.	NNP
cord-329515-ra20actc	39	43	,	,	,
cord-329515-ra20actc	39	44	1991	1991	CD
cord-329515-ra20actc	40	1	Nilsson	Nilsson	NNP
cord-329515-ra20actc	40	2	et	et	NNP
cord-329515-ra20actc	40	3	al	al	NNP
cord-329515-ra20actc	40	4	.	.	.
cord-329515-ra20actc	41	1	,	,	,
cord-329515-ra20actc	41	2	,	,	,
cord-329515-ra20actc	41	3	1993	1993	CD
cord-329515-ra20actc	42	1	Nilsson	Nilsson	NNP
cord-329515-ra20actc	42	2	et	et	NNP
cord-329515-ra20actc	42	3	al	al	NNP
cord-329515-ra20actc	42	4	.	.	NNP
cord-329515-ra20actc	42	5	,	,	,
cord-329515-ra20actc	42	6	,	,	,
cord-329515-ra20actc	42	7	1994	1994	CD
cord-329515-ra20actc	42	8	.	.	.
cord-329515-ra20actc	43	1	Recently	recently	RB
cord-329515-ra20actc	43	2	,	,	,
cord-329515-ra20actc	43	3	oligomerization	oligomerization	NN
cord-329515-ra20actc	43	4	of	of	IN
cord-329515-ra20actc	43	5	a	a	DT
cord-329515-ra20actc	43	6	chimeric	chimeric	JJ
cord-329515-ra20actc	43	7	protein	protein	NN
cord-329515-ra20actc	43	8	containing	contain	VBG
cord-329515-ra20actc	43	9	the	the	DT
cord-329515-ra20actc	43	10	first	first	JJ
cord-329515-ra20actc	43	11	membrane	membrane	NN
cord-329515-ra20actc	43	12	-	-	HYPH
cord-329515-ra20actc	43	13	spanning	span	VBG
cord-329515-ra20actc	43	14	domain	domain	NN
cord-329515-ra20actc	43	15	of	of	IN
cord-329515-ra20actc	43	16	the	the	DT
cord-329515-ra20actc	43	17	M	M	NNP
cord-329515-ra20actc	43	18	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	43	19	of	of	IN
cord-329515-ra20actc	43	20	avian	avian	JJ
cord-329515-ra20actc	43	21	coronavirus	coronavirus	NN
cord-329515-ra20actc	43	22	has	have	VBZ
cord-329515-ra20actc	43	23	been	be	VBN
cord-329515-ra20actc	43	24	correlated	correlate	VBN
cord-329515-ra20actc	43	25	to	to	IN
cord-329515-ra20actc	43	26	its	-PRON-	PRP$
cord-329515-ra20actc	43	27	retention	retention	NN
cord-329515-ra20actc	43	28	in	in	IN
cord-329515-ra20actc	43	29	the	the	DT
cord-329515-ra20actc	43	30	Golgi	Golgi	NNP
cord-329515-ra20actc	43	31	apparatus	apparatus	NN
cord-329515-ra20actc	43	32	(	(	-LRB-
cord-329515-ra20actc	43	33	Weisz	Weisz	NNP
cord-329515-ra20actc	43	34	et	et	NNP
cord-329515-ra20actc	43	35	al	al	NNP
cord-329515-ra20actc	43	36	.	.	NNP
cord-329515-ra20actc	43	37	,	,	,
cord-329515-ra20actc	43	38	1993	1993	CD
cord-329515-ra20actc	43	39	)	)	-RRB-
cord-329515-ra20actc	43	40	.	.	.
cord-329515-ra20actc	44	1	In	in	IN
cord-329515-ra20actc	44	2	contrast	contrast	NN
cord-329515-ra20actc	44	3	to	to	IN
cord-329515-ra20actc	44	4	the	the	DT
cord-329515-ra20actc	44	5	considerable	considerable	JJ
cord-329515-ra20actc	44	6	progress	progress	NN
cord-329515-ra20actc	44	7	that	that	WDT
cord-329515-ra20actc	44	8	has	have	VBZ
cord-329515-ra20actc	44	9	been	be	VBN
cord-329515-ra20actc	44	10	made	make	VBN
cord-329515-ra20actc	44	11	in	in	IN
cord-329515-ra20actc	44	12	understanding	understand	VBG
cord-329515-ra20actc	44	13	protein	protein	NN
cord-329515-ra20actc	44	14	localization	localization	NN
cord-329515-ra20actc	44	15	in	in	IN
cord-329515-ra20actc	44	16	the	the	DT
cord-329515-ra20actc	44	17	ER	ER	NNP
cord-329515-ra20actc	44	18	and	and	CC
cord-329515-ra20actc	44	19	the	the	DT
cord-329515-ra20actc	44	20	Golgi	Golgi	NNP
cord-329515-ra20actc	44	21	apparatus	apparatus	NN
cord-329515-ra20actc	44	22	,	,	,
cord-329515-ra20actc	44	23	it	-PRON-	PRP
cord-329515-ra20actc	44	24	is	be	VBZ
cord-329515-ra20actc	44	25	presently	presently	RB
cord-329515-ra20actc	44	26	unclear	unclear	JJ
cord-329515-ra20actc	44	27	how	how	WRB
cord-329515-ra20actc	44	28	the	the	DT
cord-329515-ra20actc	44	29	recently	recently	RB
cord-329515-ra20actc	44	30	identified	identify	VBN
cord-329515-ra20actc	44	31	ER	ER	NNP
cord-329515-ra20actc	44	32	-	-	HYPH
cord-329515-ra20actc	44	33	Golgi	Golgi	NNP
cord-329515-ra20actc	44	34	intermediate	intermediate	JJ
cord-329515-ra20actc	44	35	compartment	compartment	NN
cord-329515-ra20actc	44	36	(	(	-LRB-
cord-329515-ra20actc	44	37	ERGIC	ERGIC	NNP
cord-329515-ra20actc	44	38	)	)	-RRB-
cord-329515-ra20actc	44	39	1	1	CD
cord-329515-ra20actc	44	40	maintains	maintain	VBZ
cord-329515-ra20actc	44	41	its	-PRON-	PRP$
cord-329515-ra20actc	44	42	resident	resident	JJ
cord-329515-ra20actc	44	43	population	population	NN
cord-329515-ra20actc	44	44	of	of	IN
cord-329515-ra20actc	44	45	proteins	protein	NNS
cord-329515-ra20actc	44	46	(	(	-LRB-
cord-329515-ra20actc	44	47	for	for	IN
cord-329515-ra20actc	44	48	a	a	DT
cord-329515-ra20actc	44	49	review	review	NN
cord-329515-ra20actc	44	50	see	see	VB
cord-329515-ra20actc	44	51	Hauri	Hauri	NNP
cord-329515-ra20actc	44	52	and	and	CC
cord-329515-ra20actc	44	53	Schweizer	Schweizer	NNP
cord-329515-ra20actc	44	54	,	,	,
cord-329515-ra20actc	44	55	1992	1992	CD
cord-329515-ra20actc	44	56	)	)	-RRB-
cord-329515-ra20actc	44	57	.	.	.
cord-329515-ra20actc	45	1	The	the	DT
cord-329515-ra20actc	45	2	ERGIC	ERGIC	NNP
cord-329515-ra20actc	45	3	comprises	comprise	VBZ
cord-329515-ra20actc	45	4	a	a	DT
cord-329515-ra20actc	45	5	membrane	membrane	NN
cord-329515-ra20actc	45	6	system	system	NN
cord-329515-ra20actc	45	7	interposed	interpose	VBN
cord-329515-ra20actc	45	8	between	between	IN
cord-329515-ra20actc	45	9	the	the	DT
cord-329515-ra20actc	45	10	rough	rough	JJ
cord-329515-ra20actc	45	11	ER	er	NN
cord-329515-ra20actc	45	12	and	and	CC
cord-329515-ra20actc	45	13	the	the	DT
cord-329515-ra20actc	45	14	cis	cis	NNP
cord-329515-ra20actc	45	15	side	side	NN
cord-329515-ra20actc	45	16	of	of	IN
cord-329515-ra20actc	45	17	the	the	DT
cord-329515-ra20actc	45	18	Golgi	Golgi	NNP
cord-329515-ra20actc	45	19	apparatus	apparatus	NN
cord-329515-ra20actc	45	20	that	that	WDT
cord-329515-ra20actc	45	21	has	have	VBZ
cord-329515-ra20actc	45	22	been	be	VBN
cord-329515-ra20actc	45	23	shown	show	VBN
cord-329515-ra20actc	45	24	to	to	TO
cord-329515-ra20actc	45	25	mediate	mediate	VB
cord-329515-ra20actc	45	26	ER	ER	NNP
cord-329515-ra20actc	45	27	-	-	HYPH
cord-329515-ra20actc	45	28	to	to	IN
cord-329515-ra20actc	45	29	-	-	HYPH
cord-329515-ra20actc	45	30	Golgi	golgi	NN
cord-329515-ra20actc	45	31	exocytic	exocytic	JJ
cord-329515-ra20actc	45	32	protein	protein	NN
cord-329515-ra20actc	45	33	transport	transport	NN
cord-329515-ra20actc	45	34	(	(	-LRB-
cord-329515-ra20actc	45	35	Schweizer	Schweizer	NNP
cord-329515-ra20actc	45	36	et	et	NNP
cord-329515-ra20actc	45	37	al	al	NNP
cord-329515-ra20actc	45	38	.	.	NNP
cord-329515-ra20actc	45	39	,	,	,
cord-329515-ra20actc	45	40	1990	1990	CD
cord-329515-ra20actc	45	41	;	;	:
cord-329515-ra20actc	46	1	Lotti	Lotti	NNP
cord-329515-ra20actc	46	2	et	et	NNP
cord-329515-ra20actc	46	3	al	al	NNP
cord-329515-ra20actc	46	4	.	.	NNP
cord-329515-ra20actc	46	5	,	,	,
cord-329515-ra20actc	46	6	1992	1992	CD
cord-329515-ra20actc	46	7	)	)	-RRB-
cord-329515-ra20actc	46	8	.	.	.
cord-329515-ra20actc	47	1	The	the	DT
cord-329515-ra20actc	47	2	ERGIC	ERGIC	NNP
cord-329515-ra20actc	47	3	may	may	MD
cord-329515-ra20actc	47	4	correspond	correspond	VB
cord-329515-ra20actc	47	5	to	to	IN
cord-329515-ra20actc	47	6	the	the	DT
cord-329515-ra20actc	47	7	"	"	``
cord-329515-ra20actc	47	8	budding	budding	JJ
cord-329515-ra20actc	47	9	compartment	compartment	NN
cord-329515-ra20actc	47	10	"	"	''
cord-329515-ra20actc	47	11	of	of	IN
cord-329515-ra20actc	47	12	mouse	mouse	NN
cord-329515-ra20actc	47	13	coronavirus	coronavirus	NN
cord-329515-ra20actc	47	14	(	(	-LRB-
cord-329515-ra20actc	47	15	Tooze	Tooze	NNP
cord-329515-ra20actc	47	16	et	et	NNP
cord-329515-ra20actc	47	17	al	al	NNP
cord-329515-ra20actc	47	18	.	.	NNP
cord-329515-ra20actc	47	19	,	,	,
cord-329515-ra20actc	47	20	1988	1988	CD
cord-329515-ra20actc	47	21	;	;	:
cord-329515-ra20actc	47	22	Krijnse	Krijnse	NNP
cord-329515-ra20actc	47	23	-	-	HYPH
cord-329515-ra20actc	47	24	Locker	Locker	NNP
cord-329515-ra20actc	47	25	et	et	FW
cord-329515-ra20actc	47	26	al	al	NNP
cord-329515-ra20actc	47	27	.	.	NNP
cord-329515-ra20actc	47	28	,	,	,
cord-329515-ra20actc	47	29	1994	1994	CD
cord-329515-ra20actc	47	30	)	)	-RRB-
cord-329515-ra20actc	47	31	and	and	CC
cord-329515-ra20actc	47	32	to	to	IN
cord-329515-ra20actc	47	33	the	the	DT
cord-329515-ra20actc	47	34	"	"	``
cord-329515-ra20actc	47	35	pre	pre	JJ
cord-329515-ra20actc	47	36	-	-	JJ
cord-329515-ra20actc	47	37	Golgi	golgi	JJ
cord-329515-ra20actc	47	38	vacuoles	vacuole	NNS
cord-329515-ra20actc	47	39	"	"	''
cord-329515-ra20actc	47	40	of	of	IN
cord-329515-ra20actc	47	41	Semliki	Semliki	NNP
cord-329515-ra20actc	47	42	Forest	Forest	NNP
cord-329515-ra20actc	47	43	virus	virus	NN
cord-329515-ra20actc	47	44	-	-	HYPH
cord-329515-ra20actc	47	45	infected	infect	VBN
cord-329515-ra20actc	47	46	cells	cell	NNS
cord-329515-ra20actc	47	47	(	(	-LRB-
cord-329515-ra20actc	47	48	Saraste	Saraste	NNP
cord-329515-ra20actc	47	49	and	and	CC
cord-329515-ra20actc	47	50	Kuismanen	Kuismanen	NNP
cord-329515-ra20actc	47	51	,	,	,
cord-329515-ra20actc	47	52	1984	1984	CD
cord-329515-ra20actc	47	53	)	)	-RRB-
cord-329515-ra20actc	47	54	.	.	.
cord-329515-ra20actc	48	1	Isolation	isolation	NN
cord-329515-ra20actc	48	2	of	of	IN
cord-329515-ra20actc	48	3	the	the	DT
cord-329515-ra20actc	48	4	ERGIC	ERGIC	NNP
cord-329515-ra20actc	48	5	from	from	IN
cord-329515-ra20actc	48	6	Vero	Vero	NNP
cord-329515-ra20actc	48	7	cells	cell	NNS
cord-329515-ra20actc	48	8	indicated	indicate	VBD
cord-329515-ra20actc	48	9	that	that	IN
cord-329515-ra20actc	48	10	this	this	DT
cord-329515-ra20actc	48	11	compartment	compartment	NN
cord-329515-ra20actc	48	12	has	have	VBZ
cord-329515-ra20actc	48	13	unique	unique	JJ
cord-329515-ra20actc	48	14	properties	property	NNS
cord-329515-ra20actc	48	15	since	since	IN
cord-329515-ra20actc	48	16	it	-PRON-	PRP
cord-329515-ra20actc	48	17	does	do	VBZ
cord-329515-ra20actc	48	18	not	not	RB
cord-329515-ra20actc	48	19	share	share	VB
cord-329515-ra20actc	48	20	major	major	JJ
cord-329515-ra20actc	48	21	marker	marker	NN
cord-329515-ra20actc	48	22	proteins	protein	NNS
cord-329515-ra20actc	48	23	with	with	IN
cord-329515-ra20actc	48	24	its	-PRON-	PRP$
cord-329515-ra20actc	48	25	direct	direct	JJ
cord-329515-ra20actc	48	26	neighbor	neighbor	NN
cord-329515-ra20actc	48	27	organelles	organelle	NNS
cord-329515-ra20actc	48	28	,	,	,
cord-329515-ra20actc	48	29	the	the	DT
cord-329515-ra20actc	48	30	rough	rough	JJ
cord-329515-ra20actc	48	31	ER	ER	NNP
cord-329515-ra20actc	48	32	and	and	CC
cord-329515-ra20actc	48	33	cis	cis	NNP
cord-329515-ra20actc	48	34	-	-	HYPH
cord-329515-ra20actc	48	35	Golgi	Golgi	NNP
cord-329515-ra20actc	48	36	apparatus	apparatus	NN
cord-329515-ra20actc	48	37	(	(	-LRB-
cord-329515-ra20actc	48	38	Schweizer	Schweizer	NNP
cord-329515-ra20actc	48	39	et	et	NNP
cord-329515-ra20actc	48	40	al	al	NNP
cord-329515-ra20actc	48	41	.	.	NNP
cord-329515-ra20actc	48	42	,	,	,
cord-329515-ra20actc	48	43	1991	1991	CD
cord-329515-ra20actc	48	44	)	)	-RRB-
cord-329515-ra20actc	48	45	.	.	.
cord-329515-ra20actc	49	1	Currently	currently	RB
cord-329515-ra20actc	49	2	,	,	,
cord-329515-ra20actc	49	3	a	a	DT
cord-329515-ra20actc	49	4	limited	limited	JJ
cord-329515-ra20actc	49	5	number	number	NN
cord-329515-ra20actc	49	6	of	of	IN
cord-329515-ra20actc	49	7	marker	marker	NN
cord-329515-ra20actc	49	8	proteins	protein	NNS
cord-329515-ra20actc	49	9	are	be	VBP
cord-329515-ra20actc	49	10	available	available	JJ
cord-329515-ra20actc	49	11	for	for	IN
cord-329515-ra20actc	49	12	the	the	DT
cord-329515-ra20actc	49	13	ERGIC	ERGIC	NNP
cord-329515-ra20actc	49	14	.	.	.
cord-329515-ra20actc	50	1	The	the	DT
cord-329515-ra20actc	50	2	ERGIC	ERGIC	NNP
cord-329515-ra20actc	50	3	was	be	VBD
cord-329515-ra20actc	50	4	originally	originally	RB
cord-329515-ra20actc	50	5	defined	define	VBN
cord-329515-ra20actc	50	6	by	by	IN
cord-329515-ra20actc	50	7	a	a	DT
cord-329515-ra20actc	50	8	53-kD	53-kd	CD
cord-329515-ra20actc	50	9	type	type	NN
cord-329515-ra20actc	50	10	I	-PRON-	PRP
cord-329515-ra20actc	50	11	transmembrane	transmembrane	NN
cord-329515-ra20actc	50	12	protein	protein	NN
cord-329515-ra20actc	50	13	(	(	-LRB-
cord-329515-ra20actc	50	14	Schweizer	Schweizer	NNP
cord-329515-ra20actc	50	15	et	et	NNP
cord-329515-ra20actc	50	16	al	al	NNP
cord-329515-ra20actc	50	17	.	.	NNP
cord-329515-ra20actc	50	18	,	,	,
cord-329515-ra20actc	50	19	1988	1988	CD
cord-329515-ra20actc	50	20	)	)	-RRB-
cord-329515-ra20actc	50	21	termed	term	VBD
cord-329515-ra20actc	50	22	ERGIC-53	ergic-53	CD
cord-329515-ra20actc	50	23	.	.	.
cord-329515-ra20actc	51	1	ERGIC-53	ERGIC-53	NNP
cord-329515-ra20actc	51	2	is	be	VBZ
cord-329515-ra20actc	51	3	specifically	specifically	RB
cord-329515-ra20actc	51	4	localized	localize	VBN
cord-329515-ra20actc	51	5	in	in	IN
cord-329515-ra20actc	51	6	the	the	DT
cord-329515-ra20actc	51	7	ERGIC	ERGIC	NNP
cord-329515-ra20actc	51	8	at	at	IN
cord-329515-ra20actc	51	9	37	37	CD
cord-329515-ra20actc	51	10	°	°	NN
cord-329515-ra20actc	51	11	C	c	NN
cord-329515-ra20actc	51	12	but	but	CC
cord-329515-ra20actc	51	13	undergoes	undergo	VBZ
cord-329515-ra20actc	51	14	a	a	DT
cord-329515-ra20actc	51	15	temperature	temperature	NN
cord-329515-ra20actc	51	16	-	-	HYPH
cord-329515-ra20actc	51	17	dependent	dependent	JJ
cord-329515-ra20actc	51	18	redistribution	redistribution	NN
cord-329515-ra20actc	51	19	(	(	-LRB-
cord-329515-ra20actc	51	20	Lippincott	Lippincott	NNP
cord-329515-ra20actc	51	21	-	-	HYPH
cord-329515-ra20actc	51	22	Schwartz	Schwartz	NNP
cord-329515-ra20actc	51	23	et	et	NNP
cord-329515-ra20actc	51	24	al	al	NNP
cord-329515-ra20actc	51	25	.	.	NNP
cord-329515-ra20actc	51	26	,	,	,
cord-329515-ra20actc	51	27	1990	1990	CD
cord-329515-ra20actc	51	28	;	;	:
cord-329515-ra20actc	52	1	Schweizer	Schweizer	NNP
cord-329515-ra20actc	52	2	et	et	NNP
cord-329515-ra20actc	52	3	al	al	NNP
cord-329515-ra20actc	52	4	.	.	NNP
cord-329515-ra20actc	52	5	,	,	,
cord-329515-ra20actc	52	6	1990	1990	CD
cord-329515-ra20actc	52	7	)	)	-RRB-
cord-329515-ra20actc	52	8	which	which	WDT
cord-329515-ra20actc	52	9	suggested	suggest	VBD
cord-329515-ra20actc	52	10	that	that	IN
cord-329515-ra20actc	52	11	it	-PRON-	PRP
cord-329515-ra20actc	52	12	may	may	MD
cord-329515-ra20actc	52	13	follow	follow	VB
cord-329515-ra20actc	52	14	a	a	DT
cord-329515-ra20actc	52	15	recycling	recycling	NN
cord-329515-ra20actc	52	16	pathway	pathway	NN
cord-329515-ra20actc	52	17	(	(	-LRB-
cord-329515-ra20actc	52	18	Hauri	Hauri	NNP
cord-329515-ra20actc	52	19	and	and	CC
cord-329515-ra20actc	52	20	Schweizer	Schweizer	NNP
cord-329515-ra20actc	52	21	,	,	,
cord-329515-ra20actc	52	22	1992	1992	CD
cord-329515-ra20actc	52	23	)	)	-RRB-
cord-329515-ra20actc	52	24	.	.	.
cord-329515-ra20actc	53	1	Another	another	DT
cord-329515-ra20actc	53	2	marker	marker	NN
cord-329515-ra20actc	53	3	for	for	IN
cord-329515-ra20actc	53	4	the	the	DT
cord-329515-ra20actc	53	5	ERGIC	ERGIC	NNP
cord-329515-ra20actc	53	6	is	be	VBZ
cord-329515-ra20actc	53	7	the	the	DT
cord-329515-ra20actc	53	8	small	small	JJ
cord-329515-ra20actc	53	9	GTP	gtp	NN
cord-329515-ra20actc	53	10	-	-	HYPH
cord-329515-ra20actc	53	11	binding	bind	VBG
cord-329515-ra20actc	53	12	protein	protein	NN
cord-329515-ra20actc	53	13	rab2p	rab2p	NNP
cord-329515-ra20actc	54	1	(	(	-LRB-
cord-329515-ra20actc	54	2	Chavrier	Chavrier	NNP
cord-329515-ra20actc	54	3	et	et	NNP
cord-329515-ra20actc	54	4	al	al	NNP
cord-329515-ra20actc	54	5	.	.	NNP
cord-329515-ra20actc	54	6	,	,	,
cord-329515-ra20actc	54	7	1990	1990	CD
cord-329515-ra20actc	54	8	)	)	-RRB-
cord-329515-ra20actc	54	9	.	.	.
cord-329515-ra20actc	55	1	Beta	beta	NN
cord-329515-ra20actc	55	2	-	-	HYPH
cord-329515-ra20actc	55	3	COP	cop	NN
cord-329515-ra20actc	55	4	,	,	,
cord-329515-ra20actc	55	5	a	a	DT
cord-329515-ra20actc	55	6	major	major	JJ
cord-329515-ra20actc	55	7	component	component	NN
cord-329515-ra20actc	55	8	of	of	IN
cord-329515-ra20actc	55	9	non	non	JJ
cord-329515-ra20actc	55	10	-	-	JJ
cord-329515-ra20actc	55	11	clathrin	clathrin	JJ
cord-329515-ra20actc	55	12	-	-	HYPH
cord-329515-ra20actc	55	13	coated	coat	VBN
cord-329515-ra20actc	55	14	vesicles	vesicle	NNS
cord-329515-ra20actc	55	15	,	,	,
cord-329515-ra20actc	55	16	also	also	RB
cord-329515-ra20actc	55	17	associates	associate	VBZ
cord-329515-ra20actc	55	18	with	with	IN
cord-329515-ra20actc	55	19	the	the	DT
cord-329515-ra20actc	55	20	ERGIC	ERGIC	NNP
cord-329515-ra20actc	55	21	at	at	IN
cord-329515-ra20actc	55	22	15	15	CD
cord-329515-ra20actc	55	23	°	°	NN
cord-329515-ra20actc	55	24	C	c	NN
cord-329515-ra20actc	55	25	(	(	-LRB-
cord-329515-ra20actc	55	26	Duden	Duden	NNP
cord-329515-ra20actc	55	27	et	et	FW
cord-329515-ra20actc	55	28	al	al	NNP
cord-329515-ra20actc	55	29	.	.	NNP
cord-329515-ra20actc	55	30	,	,	,
cord-329515-ra20actc	55	31	1991	1991	CD
cord-329515-ra20actc	55	32	)	)	-RRB-
cord-329515-ra20actc	55	33	.	.	.
cord-329515-ra20actc	56	1	The	the	DT
cord-329515-ra20actc	56	2	p58-positive	p58-positive	JJ
cord-329515-ra20actc	56	3	pre	pre	JJ
cord-329515-ra20actc	56	4	-	-	JJ
cord-329515-ra20actc	56	5	Golgi	golgi	JJ
cord-329515-ra20actc	56	6	elements	element	NNS
cord-329515-ra20actc	56	7	described	describe	VBN
cord-329515-ra20actc	56	8	by	by	IN
cord-329515-ra20actc	56	9	Saraste	Saraste	NNP
cord-329515-ra20actc	56	10	and	and	CC
cord-329515-ra20actc	56	11	Svenson	Svenson	NNP
cord-329515-ra20actc	56	12	(	(	-LRB-
cord-329515-ra20actc	56	13	1991	1991	CD
cord-329515-ra20actc	56	14	)	)	-RRB-
cord-329515-ra20actc	56	15	may	may	MD
cord-329515-ra20actc	56	16	also	also	RB
cord-329515-ra20actc	56	17	be	be	VB
cord-329515-ra20actc	56	18	part	part	NN
cord-329515-ra20actc	56	19	of	of	IN
cord-329515-ra20actc	56	20	the	the	DT
cord-329515-ra20actc	56	21	ERGIC	ERGIC	NNP
cord-329515-ra20actc	56	22	.	.	.
cord-329515-ra20actc	57	1	The	the	DT
cord-329515-ra20actc	57	2	only	only	JJ
cord-329515-ra20actc	57	3	membrane	membrane	NN
cord-329515-ra20actc	57	4	protein	protein	NN
cord-329515-ra20actc	57	5	characterized	characterize	VBD
cord-329515-ra20actc	57	6	and	and	CC
cord-329515-ra20actc	57	7	cloned	clone	VBN
cord-329515-ra20actc	57	8	so	so	RB
cord-329515-ra20actc	57	9	far	far	RB
cord-329515-ra20actc	57	10	with	with	IN
cord-329515-ra20actc	57	11	a	a	DT
cord-329515-ra20actc	57	12	stable	stable	JJ
cord-329515-ra20actc	57	13	ER	ER	NNP
cord-329515-ra20actc	57	14	-	-	HYPH
cord-329515-ra20actc	57	15	Golgi	golgi	NN
cord-329515-ra20actc	57	16	intermediate	intermediate	JJ
cord-329515-ra20actc	57	17	localization	localization	NN
cord-329515-ra20actc	57	18	is	be	VBZ
cord-329515-ra20actc	57	19	p63	p63	NNP
cord-329515-ra20actc	57	20	(	(	-LRB-
cord-329515-ra20actc	57	21	Schweizer	Schweizer	NNP
cord-329515-ra20actc	57	22	et	et	NNP
cord-329515-ra20actc	57	23	al	al	NNP
cord-329515-ra20actc	57	24	.	.	NNP
cord-329515-ra20actc	57	25	,	,	,
cord-329515-ra20actc	57	26	1993a	1993a	CD
cord-329515-ra20actc	57	27	,	,	,
cord-329515-ra20actc	57	28	b	b	LS
cord-329515-ra20actc	57	29	)	)	-RRB-
cord-329515-ra20actc	57	30	.	.	.
cord-329515-ra20actc	58	1	mAbs	mAbs	NNP
cord-329515-ra20actc	58	2	against	against	IN
cord-329515-ra20actc	58	3	p63	p63	NNP
cord-329515-ra20actc	58	4	recognized	recognize	VBD
cord-329515-ra20actc	58	5	an	an	DT
cord-329515-ra20actc	58	6	extended	extended	JJ
cord-329515-ra20actc	58	7	ER	ER	NNP
cord-329515-ra20actc	58	8	-	-	HYPH
cord-329515-ra20actc	58	9	Golgi	golgi	NN
cord-329515-ra20actc	58	10	intermediate	intermediate	JJ
cord-329515-ra20actc	58	11	membrane	membrane	NN
cord-329515-ra20actc	58	12	structure	structure	NN
cord-329515-ra20actc	58	13	which	which	WDT
cord-329515-ra20actc	58	14	indicated	indicate	VBD
cord-329515-ra20actc	58	15	that	that	IN
cord-329515-ra20actc	58	16	the	the	DT
cord-329515-ra20actc	58	17	ERGIC	ERGIC	NNP
cord-329515-ra20actc	58	18	may	may	MD
cord-329515-ra20actc	58	19	be	be	VB
cord-329515-ra20actc	58	20	larger	large	JJR
cord-329515-ra20actc	58	21	than	than	IN
cord-329515-ra20actc	58	22	previously	previously	RB
cord-329515-ra20actc	58	23	suggested	suggest	VBN
cord-329515-ra20actc	58	24	by	by	IN
cord-329515-ra20actc	58	25	the	the	DT
cord-329515-ra20actc	58	26	ERGIC-53	ERGIC-53	NNP
cord-329515-ra20actc	58	27	analysis	analysis	NN
cord-329515-ra20actc	58	28	.	.	.
cord-329515-ra20actc	59	1	Unlike	unlike	IN
cord-329515-ra20actc	59	2	ERGIG-53	ERGIG-53	NNP
cord-329515-ra20actc	59	3	,	,	,
cord-329515-ra20actc	59	4	the	the	DT
cord-329515-ra20actc	59	5	distribution	distribution	NN
cord-329515-ra20actc	59	6	of	of	IN
cord-329515-ra20actc	59	7	p63	p63	CD
cord-329515-ra20actc	59	8	was	be	VBD
cord-329515-ra20actc	59	9	insensitive	insensitive	JJ
cord-329515-ra20actc	59	10	to	to	IN
cord-329515-ra20actc	59	11	organelle	organelle	NN
cord-329515-ra20actc	59	12	perturbants	perturbant	NNS
cord-329515-ra20actc	59	13	such	such	JJ
cord-329515-ra20actc	59	14	as	as	IN
cord-329515-ra20actc	59	15	low	low	JJ
cord-329515-ra20actc	59	16	temperature	temperature	NN
cord-329515-ra20actc	59	17	and	and	CC
cord-329515-ra20actc	59	18	brefeldin	brefeldin	NNS
cord-329515-ra20actc	59	19	A	A	NNP
cord-329515-ra20actc	60	1	(	(	-LRB-
cord-329515-ra20actc	60	2	Schweizer	Schweizer	NNP
cord-329515-ra20actc	60	3	et	et	NNP
cord-329515-ra20actc	60	4	al	al	NNP
cord-329515-ra20actc	60	5	.	.	NNP
cord-329515-ra20actc	60	6	,	,	,
cord-329515-ra20actc	60	7	1993a	1993a	CD
cord-329515-ra20actc	60	8	)	)	-RRB-
cord-329515-ra20actc	60	9	.	.	.
cord-329515-ra20actc	61	1	Sequence	sequence	NN
cord-329515-ra20actc	61	2	analysis	analysis	NN
cord-329515-ra20actc	61	3	together	together	RB
cord-329515-ra20actc	61	4	with	with	IN
cord-329515-ra20actc	61	5	biochemical	biochemical	JJ
cord-329515-ra20actc	61	6	data	datum	NNS
cord-329515-ra20actc	61	7	demonstrated	demonstrate	VBD
cord-329515-ra20actc	61	8	that	that	IN
cord-329515-ra20actc	61	9	p63	p63	NN
cord-329515-ra20actc	61	10	is	be	VBZ
cord-329515-ra20actc	61	11	a	a	DT
cord-329515-ra20actc	61	12	nonglycosylated	nonglycosylated	JJ
cord-329515-ra20actc	61	13	,	,	,
cord-329515-ra20actc	61	14	reversibly	reversibly	RB
cord-329515-ra20actc	61	15	palmitoylated	palmitoylate	VBD
cord-329515-ra20actc	61	16	type	type	NN
cord-329515-ra20actc	61	17	II	II	NNP
cord-329515-ra20actc	61	18	transmembrane	transmembrane	NN
cord-329515-ra20actc	61	19	protein	protein	NN
cord-329515-ra20actc	61	20	with	with	IN
cord-329515-ra20actc	61	21	a	a	DT
cord-329515-ra20actc	61	22	106	106	CD
cord-329515-ra20actc	61	23	amino	amino	NN
cord-329515-ra20actc	61	24	acid	acid	NN
cord-329515-ra20actc	61	25	NHe	nhe	NN
cord-329515-ra20actc	61	26	-	-	HYPH
cord-329515-ra20actc	61	27	terminal	terminal	NN
cord-329515-ra20actc	61	28	cytosolic	cytosolic	JJ
cord-329515-ra20actc	61	29	tall	tall	JJ
cord-329515-ra20actc	61	30	,	,	,
cord-329515-ra20actc	61	31	a	a	DT
cord-329515-ra20actc	61	32	single	single	JJ
cord-329515-ra20actc	61	33	transmembrane	transmembrane	NN
cord-329515-ra20actc	61	34	domain	domain	NN
cord-329515-ra20actc	61	35	,	,	,
cord-329515-ra20actc	61	36	and	and	CC
cord-329515-ra20actc	61	37	a	a	DT
cord-329515-ra20actc	61	38	large	large	JJ
cord-329515-ra20actc	61	39	extracytoplasmic	extracytoplasmic	JJ
cord-329515-ra20actc	61	40	domain	domain	NN
cord-329515-ra20actc	61	41	of	of	IN
cord-329515-ra20actc	61	42	474	474	CD
cord-329515-ra20actc	61	43	amino	amino	JJ
cord-329515-ra20actc	61	44	acids	acid	NNS
cord-329515-ra20actc	61	45	(	(	-LRB-
cord-329515-ra20actc	61	46	Schweizer	Schweizer	NNP
cord-329515-ra20actc	61	47	et	et	NNP
cord-329515-ra20actc	61	48	al	al	NNP
cord-329515-ra20actc	61	49	.	.	NNP
cord-329515-ra20actc	61	50	,	,	,
cord-329515-ra20actc	61	51	1993a	1993a	CD
cord-329515-ra20actc	61	52	,	,	,
cord-329515-ra20actc	61	53	b	b	LS
cord-329515-ra20actc	61	54	)	)	-RRB-
cord-329515-ra20actc	61	55	.	.	.
cord-329515-ra20actc	62	1	As	as	IN
cord-329515-ra20actc	62	2	a	a	DT
cord-329515-ra20actc	62	3	first	first	JJ
cord-329515-ra20actc	62	4	step	step	NN
cord-329515-ra20actc	62	5	toward	toward	IN
cord-329515-ra20actc	62	6	elucidating	elucidate	VBG
cord-329515-ra20actc	62	7	the	the	DT
cord-329515-ra20actc	62	8	mechanisms	mechanism	NNS
cord-329515-ra20actc	62	9	that	that	WDT
cord-329515-ra20actc	62	10	determine	determine	VBP
cord-329515-ra20actc	62	11	protein	protein	NN
cord-329515-ra20actc	62	12	localization	localization	NN
cord-329515-ra20actc	62	13	between	between	IN
cord-329515-ra20actc	62	14	the	the	DT
cord-329515-ra20actc	62	15	rough	rough	JJ
cord-329515-ra20actc	62	16	ER	er	NN
cord-329515-ra20actc	62	17	and	and	CC
cord-329515-ra20actc	62	18	the	the	DT
cord-329515-ra20actc	62	19	Golgi	Golgi	NNP
cord-329515-ra20actc	62	20	apparatus	apparatus	NN
cord-329515-ra20actc	62	21	,	,	,
cord-329515-ra20actc	62	22	we	-PRON-	PRP
cord-329515-ra20actc	62	23	have	have	VBP
cord-329515-ra20actc	62	24	studied	study	VBN
cord-329515-ra20actc	62	25	the	the	DT
cord-329515-ra20actc	62	26	retention	retention	NN
cord-329515-ra20actc	62	27	of	of	IN
cord-329515-ra20actc	62	28	the	the	DT
cord-329515-ra20actc	62	29	p63	p63	CD
cord-329515-ra20actc	62	30	marker	marker	NN
cord-329515-ra20actc	62	31	protein	protein	NN
cord-329515-ra20actc	62	32	.	.	.
cord-329515-ra20actc	63	1	In	in	IN
cord-329515-ra20actc	63	2	the	the	DT
cord-329515-ra20actc	63	3	present	present	JJ
cord-329515-ra20actc	63	4	paper	paper	NN
cord-329515-ra20actc	63	5	we	-PRON-	PRP
cord-329515-ra20actc	63	6	demonstrate	demonstrate	VBP
cord-329515-ra20actc	63	7	that	that	IN
cord-329515-ra20actc	63	8	all	all	DT
cord-329515-ra20actc	63	9	three	three	CD
cord-329515-ra20actc	63	10	domains	domain	NNS
cord-329515-ra20actc	63	11	of	of	IN
cord-329515-ra20actc	63	12	p63	p63	NNS
cord-329515-ra20actc	63	13	contribute	contribute	VBP
cord-329515-ra20actc	63	14	to	to	IN
cord-329515-ra20actc	63	15	the	the	DT
cord-329515-ra20actc	63	16	proper	proper	JJ
cord-329515-ra20actc	63	17	intracellular	intracellular	JJ
cord-329515-ra20actc	63	18	localization	localization	NN
cord-329515-ra20actc	63	19	of	of	IN
cord-329515-ra20actc	63	20	this	this	DT
cord-329515-ra20actc	63	21	protein	protein	NN
cord-329515-ra20actc	63	22	.	.	.
cord-329515-ra20actc	64	1	Further	further	RB
cord-329515-ra20actc	64	2	,	,	,
cord-329515-ra20actc	64	3	the	the	DT
cord-329515-ra20actc	64	4	retention	retention	NN
cord-329515-ra20actc	64	5	of	of	IN
cord-329515-ra20actc	64	6	p63	p63	CD
cord-329515-ra20actc	64	7	correlated	correlate	VBN
cord-329515-ra20actc	64	8	with	with	IN
cord-329515-ra20actc	64	9	the	the	DT
cord-329515-ra20actc	64	10	formation	formation	NN
cord-329515-ra20actc	64	11	of	of	IN
cord-329515-ra20actc	64	12	Triton	Triton	NNP
cord-329515-ra20actc	64	13	X-100-insoluble	X-100-insoluble	NNP
cord-329515-ra20actc	64	14	1	1	CD
cord-329515-ra20actc	64	15	.	.	.
cord-329515-ra20actc	65	1	Abbreviations	abbreviation	NNS
cord-329515-ra20actc	65	2	used	use	VBN
cord-329515-ra20actc	65	3	in	in	IN
cord-329515-ra20actc	65	4	this	this	DT
cord-329515-ra20actc	65	5	paper	paper	NN
cord-329515-ra20actc	65	6	:	:	:
cord-329515-ra20actc	65	7	ERGIC	ERGIC	NNP
cord-329515-ra20actc	65	8	,	,	,
cord-329515-ra20actc	65	9	ER	ER	NNP
cord-329515-ra20actc	65	10	-	-	HYPH
cord-329515-ra20actc	65	11	Golgi	Golgi	NNP
cord-329515-ra20actc	65	12	intermediate	intermediate	JJ
cord-329515-ra20actc	65	13	compartment	compartment	NN
cord-329515-ra20actc	65	14	;	;	:
cord-329515-ra20actc	65	15	DPPIV	DPPIV	NNP
cord-329515-ra20actc	65	16	,	,	,
cord-329515-ra20actc	65	17	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	65	18	IV	IV	NNP
cord-329515-ra20actc	65	19	;	;	:
cord-329515-ra20actc	65	20	wt	wt	NN
cord-329515-ra20actc	65	21	,	,	,
cord-329515-ra20actc	65	22	wild	wild	JJ
cord-329515-ra20actc	65	23	type	type	NN
cord-329515-ra20actc	65	24	.	.	.
cord-329515-ra20actc	66	1	oligomers	oligomer	NNS
cord-329515-ra20actc	66	2	,	,	,
cord-329515-ra20actc	66	3	suggesting	suggest	VBG
cord-329515-ra20actc	66	4	that	that	IN
cord-329515-ra20actc	66	5	self	self	NN
cord-329515-ra20actc	66	6	-	-	HYPH
cord-329515-ra20actc	66	7	association	association	NNP
cord-329515-ra20actc	66	8	of	of	IN
cord-329515-ra20actc	66	9	p63	p63	NNP
cord-329515-ra20actc	66	10	protein	protein	NN
cord-329515-ra20actc	66	11	may	may	MD
cord-329515-ra20actc	66	12	serve	serve	VB
cord-329515-ra20actc	66	13	as	as	IN
cord-329515-ra20actc	66	14	a	a	DT
cord-329515-ra20actc	66	15	major	major	JJ
cord-329515-ra20actc	66	16	mechanism	mechanism	NN
cord-329515-ra20actc	66	17	for	for	IN
cord-329515-ra20actc	66	18	retention	retention	NN
cord-329515-ra20actc	66	19	.	.	.
cord-329515-ra20actc	67	1	Enzymes	enzyme	NNS
cord-329515-ra20actc	67	2	used	use	VBN
cord-329515-ra20actc	67	3	in	in	IN
cord-329515-ra20actc	67	4	molecular	molecular	JJ
cord-329515-ra20actc	67	5	cloning	cloning	NN
cord-329515-ra20actc	67	6	were	be	VBD
cord-329515-ra20actc	67	7	obtained	obtain	VBN
cord-329515-ra20actc	67	8	from	from	IN
cord-329515-ra20actc	67	9	Boehringer	Boehringer	NNP
cord-329515-ra20actc	67	10	Mannheim	Mannheim	NNP
cord-329515-ra20actc	67	11	(	(	-LRB-
cord-329515-ra20actc	67	12	Indianapolis	Indianapolis	NNP
cord-329515-ra20actc	67	13	,	,	,
cord-329515-ra20actc	67	14	IN	in	IN
cord-329515-ra20actc	67	15	)	)	-RRB-
cord-329515-ra20actc	67	16	,	,	,
cord-329515-ra20actc	67	17	New	New	NNP
cord-329515-ra20actc	67	18	England	England	NNP
cord-329515-ra20actc	67	19	Biolabs	Biolabs	NNP
cord-329515-ra20actc	67	20	(	(	-LRB-
cord-329515-ra20actc	67	21	Beverly	Beverly	NNP
cord-329515-ra20actc	67	22	,	,	,
cord-329515-ra20actc	67	23	MA	MA	NNP
cord-329515-ra20actc	67	24	)	)	-RRB-
cord-329515-ra20actc	67	25	,	,	,
cord-329515-ra20actc	67	26	or	or	CC
cord-329515-ra20actc	67	27	Promega	Promega	NNP
cord-329515-ra20actc	67	28	(	(	-LRB-
cord-329515-ra20actc	67	29	Madison	Madison	NNP
cord-329515-ra20actc	67	30	,	,	,
cord-329515-ra20actc	67	31	WI	WI	NNP
cord-329515-ra20actc	67	32	)	)	-RRB-
cord-329515-ra20actc	67	33	.	.	.
cord-329515-ra20actc	68	1	DME	DME	NNP
cord-329515-ra20actc	68	2	(	(	-LRB-
cord-329515-ra20actc	68	3	4.5	4.5	CD
cord-329515-ra20actc	68	4	g/1	g/1	NN
cord-329515-ra20actc	68	5	glucose	glucose	NN
cord-329515-ra20actc	68	6	)	)	-RRB-
cord-329515-ra20actc	68	7	and	and	CC
cord-329515-ra20actc	68	8	RPMI-1640	RPMI-1640	NNP
cord-329515-ra20actc	68	9	medium	medium	NN
cord-329515-ra20actc	68	10	were	be	VBD
cord-329515-ra20actc	68	11	from	from	IN
cord-329515-ra20actc	68	12	GIBCO	GIBCO	NNP
cord-329515-ra20actc	68	13	BRL	BRL	NNP
cord-329515-ra20actc	68	14	(	(	-LRB-
cord-329515-ra20actc	68	15	Grand	Grand	NNP
cord-329515-ra20actc	68	16	Island	Island	NNP
cord-329515-ra20actc	68	17	,	,	,
cord-329515-ra20actc	68	18	NY	NY	NNP
cord-329515-ra20actc	68	19	)	)	-RRB-
cord-329515-ra20actc	68	20	;	;	:
cord-329515-ra20actc	68	21	FCS	FCS	NNP
cord-329515-ra20actc	68	22	from	from	IN
cord-329515-ra20actc	68	23	Hazleton	Hazleton	NNP
cord-329515-ra20actc	68	24	Biologics	Biologics	NNP
cord-329515-ra20actc	68	25	(	(	-LRB-
cord-329515-ra20actc	68	26	Lenexa	Lenexa	NNP
cord-329515-ra20actc	68	27	,	,	,
cord-329515-ra20actc	68	28	KS	KS	NNP
cord-329515-ra20actc	68	29	)	)	-RRB-
cord-329515-ra20actc	68	30	;	;	:
cord-329515-ra20actc	68	31	Nusera	Nusera	NNP
cord-329515-ra20actc	68	32	from	from	IN
cord-329515-ra20actc	68	33	Collaborative	Collaborative	NNP
cord-329515-ra20actc	68	34	Biomedical	Biomedical	NNP
cord-329515-ra20actc	68	35	Products	Products	NNP
cord-329515-ra20actc	68	36	(	(	-LRB-
cord-329515-ra20actc	68	37	Bedford	Bedford	NNP
cord-329515-ra20actc	68	38	,	,	,
cord-329515-ra20actc	68	39	MA	MA	NNP
cord-329515-ra20actc	68	40	)	)	-RRB-
cord-329515-ra20actc	68	41	;	;	:
cord-329515-ra20actc	68	42	DEAE	DEAE	NNP
cord-329515-ra20actc	68	43	-	-	HYPH
cord-329515-ra20actc	68	44	dextran	dextran	NN
cord-329515-ra20actc	68	45	,	,	,
cord-329515-ra20actc	68	46	chloroqulne	chloroqulne	NNP
cord-329515-ra20actc	68	47	,	,	,
cord-329515-ra20actc	68	48	CNBr	CNBr	NNS
cord-329515-ra20actc	68	49	-	-	HYPH
cord-329515-ra20actc	68	50	activated	activate	VBN
cord-329515-ra20actc	68	51	Sepharose	Sepharose	NNP
cord-329515-ra20actc	68	52	4B	4b	NN
cord-329515-ra20actc	68	53	,	,	,
cord-329515-ra20actc	68	54	and	and	CC
cord-329515-ra20actc	68	55	protease	protease	NN
cord-329515-ra20actc	68	56	inhibitors	inhibitor	NNS
cord-329515-ra20actc	68	57	were	be	VBD
cord-329515-ra20actc	68	58	from	from	IN
cord-329515-ra20actc	68	59	Sigma	Sigma	NNP
cord-329515-ra20actc	68	60	Chemical	Chemical	NNP
cord-329515-ra20actc	68	61	Co.	Co.	NNP
cord-329515-ra20actc	68	62	(	(	-LRB-
cord-329515-ra20actc	68	63	St.	St.	NNP
cord-329515-ra20actc	68	64	Louis	Louis	NNP
cord-329515-ra20actc	68	65	,	,	,
cord-329515-ra20actc	68	66	MO	MO	NNP
cord-329515-ra20actc	68	67	)	)	-RRB-
cord-329515-ra20actc	68	68	;	;	:
cord-329515-ra20actc	68	69	ECL	ECL	NNP
cord-329515-ra20actc	68	70	western	western	JJ
cord-329515-ra20actc	68	71	blotting	blotting	NN
cord-329515-ra20actc	68	72	reagents	reagent	NNS
cord-329515-ra20actc	68	73	from	from	IN
cord-329515-ra20actc	68	74	Amersham	Amersham	NNP
cord-329515-ra20actc	68	75	Corp.	Corp.	NNP
cord-329515-ra20actc	68	76	(	(	-LRB-
cord-329515-ra20actc	68	77	Arlington	Arlington	NNP
cord-329515-ra20actc	68	78	Heights	Heights	NNP
cord-329515-ra20actc	68	79	,	,	,
cord-329515-ra20actc	68	80	IL	IL	NNP
cord-329515-ra20actc	68	81	)	)	-RRB-
cord-329515-ra20actc	68	82	;	;	:
cord-329515-ra20actc	68	83	nitrocellulose	nitrocellulose	VBG
cord-329515-ra20actc	68	84	from	from	IN
cord-329515-ra20actc	68	85	Schleicher	Schleicher	NNP
cord-329515-ra20actc	68	86	and	and	CC
cord-329515-ra20actc	68	87	Schuell	Schuell	NNP
cord-329515-ra20actc	68	88	(	(	-LRB-
cord-329515-ra20actc	68	89	Keene	Keene	NNP
cord-329515-ra20actc	68	90	,	,	,
cord-329515-ra20actc	68	91	NH	NH	NNP
cord-329515-ra20actc	68	92	)	)	-RRB-
cord-329515-ra20actc	68	93	;	;	:
cord-329515-ra20actc	68	94	protein	protein	VB
cord-329515-ra20actc	68	95	A	A	NNP
cord-329515-ra20actc	68	96	-	-	HYPH
cord-329515-ra20actc	68	97	Sepharose	Sepharose	NNP
cord-329515-ra20actc	68	98	beads	bead	NNS
cord-329515-ra20actc	68	99	from	from	IN
cord-329515-ra20actc	68	100	Repligen	Repligen	NNP
cord-329515-ra20actc	68	101	Corporation	Corporation	NNP
cord-329515-ra20actc	68	102	(	(	-LRB-
cord-329515-ra20actc	68	103	Cambridge	Cambridge	NNP
cord-329515-ra20actc	68	104	,	,	,
cord-329515-ra20actc	68	105	MA	MA	NNP
cord-329515-ra20actc	68	106	)	)	-RRB-
cord-329515-ra20actc	68	107	;	;	:
cord-329515-ra20actc	68	108	FITC	FITC	NNP
cord-329515-ra20actc	68	109	goat	goat	NN
cord-329515-ra20actc	68	110	antimouse	antimouse	IN
cord-329515-ra20actc	68	111	IgG	IgG	NNP
cord-329515-ra20actc	68	112	from	from	IN
cord-329515-ra20actc	68	113	Cappel	Cappel	NNP
cord-329515-ra20actc	68	114	OVestchester	OVestchester	NNP
cord-329515-ra20actc	68	115	,	,	,
cord-329515-ra20actc	68	116	PA	PA	NNP
cord-329515-ra20actc	68	117	)	)	-RRB-
cord-329515-ra20actc	68	118	;	;	:
cord-329515-ra20actc	68	119	cell	cell	NN
cord-329515-ra20actc	68	120	culture	culture	NN
cord-329515-ra20actc	68	121	dishes	dish	NNS
cord-329515-ra20actc	68	122	from	from	IN
cord-329515-ra20actc	68	123	Falcon	Falcon	NNP
cord-329515-ra20actc	68	124	(	(	-LRB-
cord-329515-ra20actc	68	125	Becton	Becton	NNP
cord-329515-ra20actc	68	126	Dickinson	Dickinson	NNP
cord-329515-ra20actc	68	127	Co.	Co.	NNP
cord-329515-ra20actc	68	128	,	,	,
cord-329515-ra20actc	68	129	Lincoln	Lincoln	NNP
cord-329515-ra20actc	68	130	Park	Park	NNP
cord-329515-ra20actc	68	131	,	,	,
cord-329515-ra20actc	68	132	NJ	NJ	NNP
cord-329515-ra20actc	68	133	)	)	-RRB-
cord-329515-ra20actc	68	134	;	;	:
cord-329515-ra20actc	68	135	multichamber	multichamber	NNP
cord-329515-ra20actc	68	136	slides	slide	NNS
cord-329515-ra20actc	68	137	from	from	IN
cord-329515-ra20actc	68	138	Nunc	Nunc	NNP
cord-329515-ra20actc	68	139	Inc.	Inc.	NNP
cord-329515-ra20actc	68	140	(	(	-LRB-
cord-329515-ra20actc	68	141	Naperville	Naperville	NNP
cord-329515-ra20actc	68	142	,	,	,
cord-329515-ra20actc	68	143	IL	IL	NNP
cord-329515-ra20actc	68	144	)	)	-RRB-
cord-329515-ra20actc	68	145	;	;	:
cord-329515-ra20actc	68	146	and	and	CC
cord-329515-ra20actc	68	147	human	human	JJ
cord-329515-ra20actc	68	148	plasma	plasma	NN
cord-329515-ra20actc	68	149	fibronectin	fibronectin	NN
cord-329515-ra20actc	68	150	from	from	IN
cord-329515-ra20actc	68	151	the	the	DT
cord-329515-ra20actc	68	152	New	New	NNP
cord-329515-ra20actc	68	153	York	York	NNP
cord-329515-ra20actc	68	154	Blood	Blood	NNP
cord-329515-ra20actc	68	155	Center	Center	NNP
cord-329515-ra20actc	68	156	.	.	.
cord-329515-ra20actc	69	1	Oligonucleotides	oligonucleotide	NNS
cord-329515-ra20actc	69	2	were	be	VBD
cord-329515-ra20actc	69	3	synthesized	synthesize	VBN
cord-329515-ra20actc	69	4	with	with	IN
cord-329515-ra20actc	69	5	a	a	DT
cord-329515-ra20actc	69	6	solid	solid	JJ
cord-329515-ra20actc	69	7	phase	phase	NN
cord-329515-ra20actc	69	8	synthesizer	synthesizer	NN
cord-329515-ra20actc	69	9	(	(	-LRB-
cord-329515-ra20actc	69	10	380A	380A	NNP
cord-329515-ra20actc	69	11	;	;	:
cord-329515-ra20actc	69	12	Applied	Applied	NNP
cord-329515-ra20actc	69	13	Biosystems	Biosystems	NNP
cord-329515-ra20actc	69	14	,	,	,
cord-329515-ra20actc	69	15	Foster	Foster	NNP
cord-329515-ra20actc	69	16	City	City	NNP
cord-329515-ra20actc	69	17	,	,	,
cord-329515-ra20actc	69	18	CA	CA	NNP
cord-329515-ra20actc	69	19	)	)	-RRB-
cord-329515-ra20actc	69	20	by	by	IN
cord-329515-ra20actc	69	21	the	the	DT
cord-329515-ra20actc	69	22	Protein	Protein	NNP
cord-329515-ra20actc	69	23	Chemistry	Chemistry	NNP
cord-329515-ra20actc	69	24	Facility	Facility	NNP
cord-329515-ra20actc	69	25	of	of	IN
cord-329515-ra20actc	69	26	Washington	Washington	NNP
cord-329515-ra20actc	69	27	University	University	NNP
cord-329515-ra20actc	69	28	.	.	.
cord-329515-ra20actc	70	1	All	all	DT
cord-329515-ra20actc	70	2	basic	basic	JJ
cord-329515-ra20actc	70	3	DNA	dna	NN
cord-329515-ra20actc	70	4	procedures	procedure	NNS
cord-329515-ra20actc	70	5	were	be	VBD
cord-329515-ra20actc	70	6	as	as	IN
cord-329515-ra20actc	70	7	described	describe	VBN
cord-329515-ra20actc	70	8	(	(	-LRB-
cord-329515-ra20actc	70	9	Sambrook	Sambrook	NNP
cord-329515-ra20actc	70	10	et	et	NNP
cord-329515-ra20actc	70	11	al	al	NNP
cord-329515-ra20actc	70	12	.	.	NNP
cord-329515-ra20actc	70	13	,	,	,
cord-329515-ra20actc	70	14	1989	1989	CD
cord-329515-ra20actc	70	15	)	)	-RRB-
cord-329515-ra20actc	70	16	.	.	.
cord-329515-ra20actc	71	1	P63	P63	NNP
cord-329515-ra20actc	71	2	Cytoplasmic	Cytoplasmic	NNP
cord-329515-ra20actc	71	3	Tail	Tail	NNP
cord-329515-ra20actc	71	4	Mutants	Mutants	NNPS
cord-329515-ra20actc	71	5	.	.	.
cord-329515-ra20actc	72	1	The	the	DT
cord-329515-ra20actc	72	2	p63wt	p63wt	CD
cord-329515-ra20actc	72	3	cDNA	cdna	NN
cord-329515-ra20actc	72	4	was	be	VBD
cord-329515-ra20actc	72	5	as	as	IN
cord-329515-ra20actc	72	6	described	describe	VBN
cord-329515-ra20actc	72	7	previously	previously	RB
cord-329515-ra20actc	72	8	(	(	-LRB-
cord-329515-ra20actc	72	9	Schweizer	Schweizer	NNP
cord-329515-ra20actc	72	10	et	et	NNP
cord-329515-ra20actc	72	11	al	al	NNP
cord-329515-ra20actc	72	12	.	.	NNP
cord-329515-ra20actc	72	13	,	,	,
cord-329515-ra20actc	72	14	1993b	1993b	CD
cord-329515-ra20actc	72	15	)	)	-RRB-
cord-329515-ra20actc	72	16	and	and	CC
cord-329515-ra20actc	72	17	consisted	consist	VBD
cord-329515-ra20actc	72	18	of	of	IN
cord-329515-ra20actc	72	19	the	the	DT
cord-329515-ra20actc	72	20	5	5	CD
cord-329515-ra20actc	72	21	'	'	POS
cord-329515-ra20actc	72	22	untranslated	untranslated	JJ
cord-329515-ra20actc	72	23	region	region	NN
cord-329515-ra20actc	72	24	,	,	,
cord-329515-ra20actc	72	25	bpl-84	bpl-84	NNP
cord-329515-ra20actc	72	26	,	,	,
cord-329515-ra20actc	72	27	the	the	DT
cord-329515-ra20actc	72	28	1803	1803	CD
cord-329515-ra20actc	72	29	nucleotide	nucleotide	JJ
cord-329515-ra20actc	72	30	coding	code	VBG
cord-329515-ra20actc	72	31	region	region	NN
cord-329515-ra20actc	72	32	and	and	CC
cord-329515-ra20actc	72	33	1023	1023	CD
cord-329515-ra20actc	72	34	bp	bp	NNP
cord-329515-ra20actc	72	35	of	of	IN
cord-329515-ra20actc	72	36	the	the	DT
cord-329515-ra20actc	72	37	3	3	CD
cord-329515-ra20actc	72	38	'	'	POS
cord-329515-ra20actc	72	39	noncoding	noncoding	JJ
cord-329515-ra20actc	72	40	sequence	sequence	NN
cord-329515-ra20actc	72	41	.	.	.
cord-329515-ra20actc	73	1	The	the	DT
cord-329515-ra20actc	73	2	full	full	JJ
cord-329515-ra20actc	73	3	-	-	HYPH
cord-329515-ra20actc	73	4	length	length	NN
cord-329515-ra20actc	73	5	cDNA	cdna	NN
cord-329515-ra20actc	73	6	was	be	VBD
cord-329515-ra20actc	73	7	inserted	insert	VBN
cord-329515-ra20actc	73	8	into	into	IN
cord-329515-ra20actc	73	9	the	the	DT
cord-329515-ra20actc	73	10	EcoRI	ecori	NN
cord-329515-ra20actc	73	11	site	site	NN
cord-329515-ra20actc	73	12	in	in	IN
cord-329515-ra20actc	73	13	the	the	DT
cord-329515-ra20actc	73	14	polylinker	polylinker	NN
cord-329515-ra20actc	73	15	of	of	IN
cord-329515-ra20actc	73	16	the	the	DT
cord-329515-ra20actc	73	17	Bluescript	Bluescript	NNP
cord-329515-ra20actc	73	18	SK	SK	NNP
cord-329515-ra20actc	73	19	-	-	:
cord-329515-ra20actc	73	20	or	or	CC
cord-329515-ra20actc	73	21	KS	KS	NNP
cord-329515-ra20actc	73	22	-	-	HYPH
cord-329515-ra20actc	73	23	vector	vector	NN
cord-329515-ra20actc	73	24	(	(	-LRB-
cord-329515-ra20actc	73	25	Stratagene	Stratagene	NNP
cord-329515-ra20actc	73	26	,	,	,
cord-329515-ra20actc	73	27	La	La	NNP
cord-329515-ra20actc	73	28	Jolla	Jolla	NNP
cord-329515-ra20actc	73	29	,	,	,
cord-329515-ra20actc	73	30	CA	CA	NNP
cord-329515-ra20actc	73	31	)	)	-RRB-
cord-329515-ra20actc	73	32	,	,	,
cord-329515-ra20actc	73	33	respectively	respectively	RB
cord-329515-ra20actc	73	34	,	,	,
cord-329515-ra20actc	73	35	with	with	IN
cord-329515-ra20actc	73	36	the	the	DT
cord-329515-ra20actc	73	37	initiator	initiator	NN
cord-329515-ra20actc	73	38	ATG	ATG	NNP
cord-329515-ra20actc	73	39	facing	face	VBG
cord-329515-ra20actc	73	40	the	the	DT
cord-329515-ra20actc	73	41	BamHI	BamHI	NNP
cord-329515-ra20actc	73	42	restriction	restriction	NN
cord-329515-ra20actc	73	43	site	site	NN
cord-329515-ra20actc	73	44	of	of	IN
cord-329515-ra20actc	73	45	the	the	DT
cord-329515-ra20actc	73	46	polylinker	polylinker	NN
cord-329515-ra20actc	73	47	.	.	.
cord-329515-ra20actc	74	1	The	the	DT
cord-329515-ra20actc	74	2	resulting	result	VBG
cord-329515-ra20actc	74	3	constructs	construct	NNS
cord-329515-ra20actc	74	4	were	be	VBD
cord-329515-ra20actc	74	5	designated	designate	VBN
cord-329515-ra20actc	74	6	pBSK	pbsk	JJ
cord-329515-ra20actc	74	7	-	-	HYPH
cord-329515-ra20actc	74	8	p63	p63	CD
cord-329515-ra20actc	74	9	or	or	CC
cord-329515-ra20actc	74	10	pBKS	pbks	JJ
cord-329515-ra20actc	74	11	-	-	HYPH
cord-329515-ra20actc	74	12	p63	p63	CD
cord-329515-ra20actc	74	13	,	,	,
cord-329515-ra20actc	74	14	respectively	respectively	RB
cord-329515-ra20actc	74	15	.	.	.
cord-329515-ra20actc	75	1	For	for	IN
cord-329515-ra20actc	75	2	transient	transient	JJ
cord-329515-ra20actc	75	3	expression	expression	NN
cord-329515-ra20actc	75	4	in	in	IN
cord-329515-ra20actc	75	5	COS	COS	NNP
cord-329515-ra20actc	75	6	cells	cell	NNS
cord-329515-ra20actc	75	7	,	,	,
cord-329515-ra20actc	75	8	the	the	DT
cord-329515-ra20actc	75	9	p63	p63	CD
cord-329515-ra20actc	75	10	insert	insert	NN
cord-329515-ra20actc	75	11	was	be	VBD
cord-329515-ra20actc	75	12	subcloned	subclone	VBN
cord-329515-ra20actc	75	13	into	into	IN
cord-329515-ra20actc	75	14	the	the	DT
cord-329515-ra20actc	75	15	EcoRI	ecori	NN
cord-329515-ra20actc	75	16	site	site	NN
cord-329515-ra20actc	75	17	of	of	IN
cord-329515-ra20actc	75	18	the	the	DT
cord-329515-ra20actc	75	19	pECE	pece	NN
cord-329515-ra20actc	75	20	vector	vector	NN
cord-329515-ra20actc	75	21	(	(	-LRB-
cord-329515-ra20actc	75	22	kindly	kindly	RB
cord-329515-ra20actc	75	23	provided	provide	VBN
cord-329515-ra20actc	75	24	by	by	IN
cord-329515-ra20actc	75	25	Dr.	Dr.	NNP
cord-329515-ra20actc	75	26	M.	M.	NNP
cord-329515-ra20actc	75	27	Spiess	Spiess	NNP
cord-329515-ra20actc	75	28	,	,	,
cord-329515-ra20actc	75	29	Biozentrum	Biozentrum	NNP
cord-329515-ra20actc	75	30	,	,	,
cord-329515-ra20actc	75	31	Basel	Basel	NNP
cord-329515-ra20actc	75	32	,	,	,
cord-329515-ra20actc	75	33	Switzerland	Switzerland	NNP
cord-329515-ra20actc	75	34	)	)	-RRB-
cord-329515-ra20actc	76	1	(	(	-LRB-
cord-329515-ra20actc	76	2	Ellis	Ellis	NNP
cord-329515-ra20actc	76	3	ct	ct	NNP
cord-329515-ra20actc	76	4	al	al	NNP
cord-329515-ra20actc	76	5	.	.	NNP
cord-329515-ra20actc	76	6	,	,	,
cord-329515-ra20actc	76	7	1986	1986	CD
cord-329515-ra20actc	76	8	)	)	-RRB-
cord-329515-ra20actc	76	9	to	to	TO
cord-329515-ra20actc	76	10	give	give	VB
cord-329515-ra20actc	76	11	plasmid	plasmid	NNP
cord-329515-ra20actc	76	12	pECE	pece	NN
cord-329515-ra20actc	76	13	-	-	HYPH
cord-329515-ra20actc	76	14	p63	p63	NNP
cord-329515-ra20actc	76	15	.	.	.
cord-329515-ra20actc	77	1	The	the	DT
cord-329515-ra20actc	77	2	mutant	mutant	JJ
cord-329515-ra20actc	77	3	forms	form	NNS
cord-329515-ra20actc	77	4	of	of	IN
cord-329515-ra20actc	77	5	the	the	DT
cord-329515-ra20actc	77	6	p63	p63	CD
cord-329515-ra20actc	77	7	gene	gene	NN
cord-329515-ra20actc	77	8	were	be	VBD
cord-329515-ra20actc	77	9	created	create	VBN
cord-329515-ra20actc	77	10	using	use	VBG
cord-329515-ra20actc	77	11	standard	standard	JJ
cord-329515-ra20actc	77	12	PCR	PCR	NNP
cord-329515-ra20actc	77	13	protocols	protocol	NNS
cord-329515-ra20actc	77	14	(	(	-LRB-
cord-329515-ra20actc	77	15	Ho	Ho	NNP
cord-329515-ra20actc	77	16	et	et	FW
cord-329515-ra20actc	77	17	al	al	NNP
cord-329515-ra20actc	77	18	.	.	NNP
cord-329515-ra20actc	77	19	,	,	,
cord-329515-ra20actc	77	20	1989	1989	CD
cord-329515-ra20actc	77	21	)	)	-RRB-
cord-329515-ra20actc	77	22	.	.	.
cord-329515-ra20actc	78	1	All	all	DT
cord-329515-ra20actc	78	2	mutants	mutant	NNS
cord-329515-ra20actc	78	3	start	start	VBP
cord-329515-ra20actc	78	4	at	at	IN
cord-329515-ra20actc	78	5	bp78	bp78	NN
cord-329515-ra20actc	78	6	of	of	IN
cord-329515-ra20actc	78	7	the	the	DT
cord-329515-ra20actc	78	8	original	original	JJ
cord-329515-ra20actc	78	9	wild	wild	JJ
cord-329515-ra20actc	78	10	type	type	NN
cord-329515-ra20actc	78	11	(	(	-LRB-
cord-329515-ra20actc	78	12	wt	wt	NN
cord-329515-ra20actc	78	13	)	)	-RRB-
cord-329515-ra20actc	79	1	p63	p63	NNP
cord-329515-ra20actc	79	2	eDNA	eDNA	NNP
cord-329515-ra20actc	80	1	(	(	-LRB-
cord-329515-ra20actc	80	2	Schweizer	Schweizer	NNP
cord-329515-ra20actc	80	3	et	et	NNP
cord-329515-ra20actc	80	4	al	al	NNP
cord-329515-ra20actc	80	5	.	.	NNP
cord-329515-ra20actc	80	6	,	,	,
cord-329515-ra20actc	80	7	1993b	1993b	CD
cord-329515-ra20actc	80	8	)	)	-RRB-
cord-329515-ra20actc	80	9	.	.	.
cord-329515-ra20actc	81	1	The	the	DT
cord-329515-ra20actc	81	2	final	final	JJ
cord-329515-ra20actc	81	3	PCR	PCR	NNP
cord-329515-ra20actc	81	4	products	product	NNS
cord-329515-ra20actc	81	5	were	be	VBD
cord-329515-ra20actc	81	6	digested	digest	VBN
cord-329515-ra20actc	81	7	with	with	IN
cord-329515-ra20actc	81	8	BamHI	bamhi	NN
cord-329515-ra20actc	81	9	and	and	CC
cord-329515-ra20actc	81	10	used	use	VBD
cord-329515-ra20actc	81	11	to	to	TO
cord-329515-ra20actc	81	12	replace	replace	VB
cord-329515-ra20actc	81	13	the	the	DT
cord-329515-ra20actc	81	14	BamHI	bamhi	NN
cord-329515-ra20actc	81	15	-	-	HYPH
cord-329515-ra20actc	81	16	BamHI	bamhi	NN
cord-329515-ra20actc	81	17	fragment	fragment	NN
cord-329515-ra20actc	81	18	of	of	IN
cord-329515-ra20actc	81	19	pBSK	pbsk	CD
cord-329515-ra20actc	81	20	-	-	HYPH
cord-329515-ra20actc	81	21	p63	p63	CD
cord-329515-ra20actc	81	22	.	.	.
cord-329515-ra20actc	82	1	The	the	DT
cord-329515-ra20actc	82	2	entire	entire	JJ
cord-329515-ra20actc	82	3	PCR	pcr	NN
cord-329515-ra20actc	82	4	-	-	HYPH
cord-329515-ra20actc	82	5	derived	derive	VBN
cord-329515-ra20actc	82	6	fragment	fragment	NN
cord-329515-ra20actc	82	7	was	be	VBD
cord-329515-ra20actc	82	8	sequenced	sequence	VBN
cord-329515-ra20actc	82	9	by	by	IN
cord-329515-ra20actc	82	10	the	the	DT
cord-329515-ra20actc	82	11	dideoxy	dideoxy	NNP
cord-329515-ra20actc	82	12	termination	termination	NN
cord-329515-ra20actc	82	13	procedure	procedure	NN
cord-329515-ra20actc	82	14	(	(	-LRB-
cord-329515-ra20actc	82	15	Sanger	Sanger	NNP
cord-329515-ra20actc	82	16	et	et	NNP
cord-329515-ra20actc	82	17	al	al	NNP
cord-329515-ra20actc	82	18	.	.	NNP
cord-329515-ra20actc	82	19	,	,	,
cord-329515-ra20actc	82	20	1977	1977	CD
cord-329515-ra20actc	82	21	)	)	-RRB-
cord-329515-ra20actc	82	22	as	as	IN
cord-329515-ra20actc	82	23	described	describe	VBN
cord-329515-ra20actc	82	24	(	(	-LRB-
cord-329515-ra20actc	82	25	Schweizer	Schweizer	NNP
cord-329515-ra20actc	82	26	et	et	NNP
cord-329515-ra20actc	82	27	al	al	NNP
cord-329515-ra20actc	82	28	.	.	NNP
cord-329515-ra20actc	82	29	,	,	,
cord-329515-ra20actc	82	30	1993b	1993b	CD
cord-329515-ra20actc	82	31	)	)	-RRB-
cord-329515-ra20actc	82	32	.	.	.
cord-329515-ra20actc	83	1	Correct	correct	JJ
cord-329515-ra20actc	83	2	clones	clone	NNS
cord-329515-ra20actc	83	3	were	be	VBD
cord-329515-ra20actc	83	4	subcloned	subclone	VBN
cord-329515-ra20actc	83	5	into	into	IN
cord-329515-ra20actc	83	6	the	the	DT
cord-329515-ra20actc	83	7	EcoRI	ecori	NN
cord-329515-ra20actc	83	8	site	site	NN
cord-329515-ra20actc	83	9	of	of	IN
cord-329515-ra20actc	83	10	the	the	DT
cord-329515-ra20actc	83	11	pECE	pece	NN
cord-329515-ra20actc	83	12	vector	vector	NN
cord-329515-ra20actc	83	13	for	for	IN
cord-329515-ra20actc	83	14	transient	transient	JJ
cord-329515-ra20actc	83	15	expression	expression	NN
cord-329515-ra20actc	83	16	in	in	IN
cord-329515-ra20actc	83	17	COS	COS	NNP
cord-329515-ra20actc	83	18	cells	cell	NNS
cord-329515-ra20actc	83	19	.	.	.
cord-329515-ra20actc	84	1	To	to	TO
cord-329515-ra20actc	84	2	generate	generate	VB
cord-329515-ra20actc	84	3	the	the	DT
cord-329515-ra20actc	84	4	A2	A2	NNP
cord-329515-ra20actc	84	5	-	-	HYPH
cord-329515-ra20actc	84	6	101	101	CD
cord-329515-ra20actc	84	7	construct	construct	NN
cord-329515-ra20actc	84	8	(	(	-LRB-
cord-329515-ra20actc	84	9	p63	p63	NN
cord-329515-ra20actc	84	10	with	with	IN
cord-329515-ra20actc	84	11	deletion	deletion	NN
cord-329515-ra20actc	84	12	of	of	IN
cord-329515-ra20actc	84	13	amino	amino	JJ
cord-329515-ra20actc	84	14	acids	acid	NNS
cord-329515-ra20actc	84	15	2	2	CD
cord-329515-ra20actc	84	16	-	-	SYM
cord-329515-ra20actc	84	17	101	101	CD
cord-329515-ra20actc	84	18	)	)	-RRB-
cord-329515-ra20actc	84	19	,	,	,
cord-329515-ra20actc	84	20	pBSK	pBSK	NNP
cord-329515-ra20actc	84	21	-	-	HYPH
cord-329515-ra20actc	84	22	p63	p63	CD
cord-329515-ra20actc	84	23	as	as	IN
cord-329515-ra20actc	84	24	template	template	NN
cord-329515-ra20actc	84	25	together	together	RB
cord-329515-ra20actc	84	26	with	with	IN
cord-329515-ra20actc	84	27	the	the	DT
cord-329515-ra20actc	84	28	5	5	CD
cord-329515-ra20actc	84	29	'	'	''
cord-329515-ra20actc	84	30	primer	primer	NN
cord-329515-ra20actc	84	31	C	C	NNP
cord-329515-ra20actc	84	32	-	-	HYPH
cord-329515-ra20actc	84	33	CC	CC	NNP
cord-329515-ra20actc	84	34	CGC	CGC	NNP
cord-329515-ra20actc	84	35	CAT	cat	NN
cord-329515-ra20actc	84	36	GCG	GCG	NNP
cord-329515-ra20actc	84	37	CAG	CAG	NNP
cord-329515-ra20actc	84	38	GCT	GCT	NNP
cord-329515-ra20actc	84	39	CGG	CGG	NNP
cord-329515-ra20actc	84	40	CAG	CAG	NNP
cord-329515-ra20actc	84	41	GC~	GC~	:
cord-329515-ra20actc	84	42	G	G	NNP
cord-329515-ra20actc	84	43	-	-	HYPH
cord-329515-ra20actc	84	44	CT	CT	NNP
cord-329515-ra20actc	84	45	CAA	CAA	NNP
cord-329515-ra20actc	84	46	C	C	NNP
cord-329515-ra20actc	84	47	,	,	,
cord-329515-ra20actc	84	48	and	and	CC
cord-329515-ra20actc	84	49	a	a	DT
cord-329515-ra20actc	84	50	3	3	CD
cord-329515-ra20actc	84	51	'	'	NN
cord-329515-ra20actc	84	52	primer	primer	NN
cord-329515-ra20actc	84	53	corresponding	correspond	VBG
cord-329515-ra20actc	84	54	to	to	IN
cord-329515-ra20actc	84	55	nucleotides	nucleotide	NNS
cord-329515-ra20actc	84	56	774	774	CD
cord-329515-ra20actc	84	57	-	-	HYPH
cord-329515-ra20actc	84	58	791	791	CD
cord-329515-ra20actc	84	59	of	of	IN
cord-329515-ra20actc	84	60	the	the	DT
cord-329515-ra20actc	84	61	p63wt	p63wt	CD
cord-329515-ra20actc	84	62	sequence	sequence	NN
cord-329515-ra20actc	84	63	were	be	VBD
cord-329515-ra20actc	84	64	used	use	VBN
cord-329515-ra20actc	84	65	in	in	IN
cord-329515-ra20actc	84	66	the	the	DT
cord-329515-ra20actc	84	67	PCR	PCR	NNP
cord-329515-ra20actc	84	68	reaction	reaction	NN
cord-329515-ra20actc	84	69	.	.	.
cord-329515-ra20actc	85	1	In	in	IN
cord-329515-ra20actc	85	2	a	a	DT
cord-329515-ra20actc	85	3	subsequent	subsequent	JJ
cord-329515-ra20actc	85	4	PCR	pcr	NN
cord-329515-ra20actc	85	5	reaction	reaction	NN
cord-329515-ra20actc	85	6	,	,	,
cord-329515-ra20actc	85	7	the	the	DT
cord-329515-ra20actc	85	8	final	final	JJ
cord-329515-ra20actc	85	9	A2	A2	NNP
cord-329515-ra20actc	85	10	-	-	HYPH
cord-329515-ra20actc	85	11	101	101	CD
cord-329515-ra20actc	85	12	construct	construct	NN
cord-329515-ra20actc	85	13	and	and	CC
cord-329515-ra20actc	85	14	the	the	DT
cord-329515-ra20actc	85	15	5	5	CD
cord-329515-ra20actc	85	16	'	'	''
cord-329515-ra20actc	85	17	primer	primer	NN
cord-329515-ra20actc	85	18	AAG	AAG	NNP
cord-329515-ra20actc	85	19	GAT	GAT	NNP
cord-329515-ra20actc	85	20	CCG	CCG	NNP
cord-329515-ra20actc	86	1	AAT	AAT	NNP
cord-329515-ra20actc	86	2	TCG	TCG	NNP
cord-329515-ra20actc	86	3	CCC	CCC	NNP
cord-329515-ra20actc	87	1	GCC	GCC	NNP
cord-329515-ra20actc	87	2	ATG	ATG	NNP
cord-329515-ra20actc	87	3	GCT	GCT	NNP
cord-329515-ra20actc	88	1	GCA	GCA	NNP
cord-329515-ra20actc	88	2	CTC	CTC	NNP
cord-329515-ra20actc	89	1	AGG	AGG	NNP
cord-329515-ra20actc	89	2	GCG	GCG	NNP
cord-329515-ra20actc	89	3	CTC	CTC	NNP
cord-329515-ra20actc	89	4	AAC	AAC	NNP
cord-329515-ra20actc	89	5	TIT	tit	NN
cord-329515-ra20actc	89	6	were	be	VBD
cord-329515-ra20actc	89	7	used	use	VBN
cord-329515-ra20actc	89	8	to	to	TO
cord-329515-ra20actc	89	9	produce	produce	VB
cord-329515-ra20actc	89	10	the	the	DT
cord-329515-ra20actc	89	11	A2	A2	NNP
cord-329515-ra20actc	89	12	-	-	HYPH
cord-329515-ra20actc	89	13	101	101	CD
cord-329515-ra20actc	89	14	AA	AA	NNP
cord-329515-ra20actc	89	15	mutant	mutant	NN
cord-329515-ra20actc	89	16	.	.	.
cord-329515-ra20actc	90	1	The	the	DT
cord-329515-ra20actc	90	2	same	same	JJ
cord-329515-ra20actc	90	3	strategy	strategy	NN
cord-329515-ra20actc	90	4	as	as	IN
cord-329515-ra20actc	90	5	described	describe	VBN
cord-329515-ra20actc	90	6	for	for	IN
cord-329515-ra20actc	90	7	the	the	DT
cord-329515-ra20actc	90	8	construction	construction	NN
cord-329515-ra20actc	90	9	of	of	IN
cord-329515-ra20actc	90	10	A2	A2	NNP
cord-329515-ra20actc	90	11	-	-	HYPH
cord-329515-ra20actc	90	12	101	101	NNP
cord-329515-ra20actc	90	13	was	be	VBD
cord-329515-ra20actc	90	14	cartied	cartie	VBN
cord-329515-ra20actc	90	15	out	out	RP
cord-329515-ra20actc	90	16	for	for	IN
cord-329515-ra20actc	90	17	the	the	DT
cord-329515-ra20actc	90	18	A16	A16	NNP
cord-329515-ra20actc	90	19	-	-	HYPH
cord-329515-ra20actc	90	20	101	101	CD
cord-329515-ra20actc	90	21	mutant	mutant	NN
cord-329515-ra20actc	90	22	(	(	-LRB-
cord-329515-ra20actc	90	23	p63	p63	CD
cord-329515-ra20actc	90	24	with	with	IN
cord-329515-ra20actc	90	25	a	a	DT
cord-329515-ra20actc	90	26	deletion	deletion	NN
cord-329515-ra20actc	90	27	of	of	IN
cord-329515-ra20actc	90	28	amino	amino	JJ
cord-329515-ra20actc	90	29	acids	acid	NNS
cord-329515-ra20actc	90	30	16	16	CD
cord-329515-ra20actc	90	31	to	to	IN
cord-329515-ra20actc	90	32	101	101	CD
cord-329515-ra20actc	90	33	)	)	-RRB-
cord-329515-ra20actc	90	34	,	,	,
cord-329515-ra20actc	90	35	except	except	IN
cord-329515-ra20actc	90	36	for	for	IN
cord-329515-ra20actc	90	37	the	the	DT
cord-329515-ra20actc	90	38	5	5	CD
cord-329515-ra20actc	90	39	'	'	''
cord-329515-ra20actc	90	40	primer	primer	NN
cord-329515-ra20actc	90	41	that	that	WDT
cord-329515-ra20actc	90	42	was	be	VBD
cord-329515-ra20actc	90	43	GCC	GCC	NNP
cord-329515-ra20actc	90	44	CGC	CGC	NNP
cord-329515-ra20actc	90	45	CAT	CAT	NNP
cord-329515-ra20actc	90	46	GCC	GCC	NNP
cord-329515-ra20actc	90	47	CTC	CTC	NNP
cord-329515-ra20actc	90	48	GC~	GC~	NNP
cord-329515-ra20actc	91	1	CAA	CAA	NNP
cord-329515-ra20actc	91	2	ACA	ACA	NNP
cord-329515-ra20actc	91	3	AAG	AAG	NNP
cord-329515-ra20actc	91	4	~	~	:
cord-329515-ra20actc	91	5	CTC	CTC	NNP
cord-329515-ra20actc	91	6	CAA	CAA	NNP
cord-329515-ra20actc	91	7	GC.K3	GC.K3	NNP
cord-329515-ra20actc	91	8	CC~	cc~	XX
cord-329515-ra20actc	92	1	CCA	CCA	NNP
cord-329515-ra20actc	92	2	CGG	CGG	NNP
cord-329515-ra20actc	92	3	CC_~	cc_~	XX
cord-329515-ra20actc	92	4	CCG	CCG	NNP
cord-329515-ra20actc	92	5	CAG	CAG	NNP
cord-329515-ra20actc	92	6	GCT	GCT	NNP
cord-329515-ra20actc	92	7	CGG	CGG	NNP
cord-329515-ra20actc	92	8	CAG	CAG	NNP
cord-329515-ra20actc	92	9	~	~	NFP
cord-329515-ra20actc	92	10	GCT	GCT	NNP
cord-329515-ra20actc	92	11	CAA	CAA	NNP
cord-329515-ra20actc	92	12	.	.	.
cord-329515-ra20actc	93	1	All	all	DT
cord-329515-ra20actc	93	2	other	other	JJ
cord-329515-ra20actc	93	3	mutations	mutation	NNS
cord-329515-ra20actc	93	4	were	be	VBD
cord-329515-ra20actc	93	5	introduced	introduce	VBN
cord-329515-ra20actc	93	6	by	by	IN
cord-329515-ra20actc	93	7	the	the	DT
cord-329515-ra20actc	93	8	overlap	overlap	NN
cord-329515-ra20actc	93	9	extension	extension	NN
cord-329515-ra20actc	93	10	technique	technique	NN
cord-329515-ra20actc	93	11	(	(	-LRB-
cord-329515-ra20actc	93	12	Ho	Ho	NNP
cord-329515-ra20actc	93	13	et	et	FW
cord-329515-ra20actc	93	14	al	al	NNP
cord-329515-ra20actc	93	15	.	.	NNP
cord-329515-ra20actc	93	16	,	,	,
cord-329515-ra20actc	93	17	1989	1989	CD
cord-329515-ra20actc	93	18	)	)	-RRB-
cord-329515-ra20actc	93	19	using	use	VBG
cord-329515-ra20actc	93	20	bp	bp	NNP
cord-329515-ra20actc	93	21	774	774	NNP
cord-329515-ra20actc	93	22	-	-	HYPH
cord-329515-ra20actc	93	23	791	791	CD
cord-329515-ra20actc	93	24	of	of	IN
cord-329515-ra20actc	93	25	the	the	DT
cord-329515-ra20actc	93	26	p63	p63	CD
cord-329515-ra20actc	93	27	sequence	sequence	NN
cord-329515-ra20actc	93	28	and	and	CC
cord-329515-ra20actc	93	29	bp	bp	NNP
cord-329515-ra20actc	93	30	170	170	CD
cord-329515-ra20actc	93	31	-	-	SYM
cord-329515-ra20actc	93	32	193	193	CD
cord-329515-ra20actc	93	33	of	of	IN
cord-329515-ra20actc	93	34	the	the	DT
cord-329515-ra20actc	93	35	Bluescript	Bluescript	NNP
cord-329515-ra20actc	93	36	KS	KS	NNP
cord-329515-ra20actc	93	37	-	-	HYPH
cord-329515-ra20actc	93	38	vector	vector	NN
cord-329515-ra20actc	93	39	as	as	IN
cord-329515-ra20actc	93	40	downstream	downstream	JJ
cord-329515-ra20actc	93	41	and	and	CC
cord-329515-ra20actc	93	42	upstream	upstream	JJ
cord-329515-ra20actc	93	43	flanking	flanking	JJ
cord-329515-ra20actc	93	44	primers	primer	NNS
cord-329515-ra20actc	93	45	.	.	.
cord-329515-ra20actc	94	1	An	an	DT
cord-329515-ra20actc	94	2	appropriate	appropriate	JJ
cord-329515-ra20actc	94	3	partial	partial	JJ
cord-329515-ra20actc	94	4	complementary	complementary	JJ
cord-329515-ra20actc	94	5	pair	pair	NN
cord-329515-ra20actc	94	6	of	of	IN
cord-329515-ra20actc	94	7	oligonucleotides	oligonucleotide	NNS
cord-329515-ra20actc	94	8	in	in	IN
cord-329515-ra20actc	94	9	which	which	WDT
cord-329515-ra20actc	94	10	the	the	DT
cord-329515-ra20actc	94	11	desired	desire	VBN
cord-329515-ra20actc	94	12	mutation	mutation	NN
cord-329515-ra20actc	94	13	had	have	VBD
cord-329515-ra20actc	94	14	been	be	VBN
cord-329515-ra20actc	94	15	incorporated	incorporate	VBN
cord-329515-ra20actc	94	16	was	be	VBD
cord-329515-ra20actc	94	17	chosen	choose	VBN
cord-329515-ra20actc	94	18	as	as	IN
cord-329515-ra20actc	94	19	internal	internal	JJ
cord-329515-ra20actc	94	20	primers	primer	NNS
cord-329515-ra20actc	94	21	.	.	.
cord-329515-ra20actc	95	1	The	the	DT
cord-329515-ra20actc	95	2	final	final	JJ
cord-329515-ra20actc	95	3	PCR	PCR	NNP
cord-329515-ra20actc	95	4	products	product	NNS
cord-329515-ra20actc	95	5	were	be	VBD
cord-329515-ra20actc	95	6	digested	digest	VBN
cord-329515-ra20actc	95	7	with	with	IN
cord-329515-ra20actc	95	8	BamHI	bamhi	NN
cord-329515-ra20actc	95	9	and	and	CC
cord-329515-ra20actc	95	10	used	use	VBD
cord-329515-ra20actc	95	11	to	to	TO
cord-329515-ra20actc	95	12	replace	replace	VB
cord-329515-ra20actc	95	13	the	the	DT
cord-329515-ra20actc	95	14	BamHI	bamhi	NN
cord-329515-ra20actc	95	15	-	-	HYPH
cord-329515-ra20actc	95	16	BamHI	bamhi	NN
cord-329515-ra20actc	95	17	fragment	fragment	NN
cord-329515-ra20actc	95	18	ofpBKS	ofpBKS	NNP
cord-329515-ra20actc	95	19	-	-	HYPH
cord-329515-ra20actc	95	20	AI6	AI6	NNP
cord-329515-ra20actc	95	21	-	-	HYPH
cord-329515-ra20actc	95	22	101	101	CD
cord-329515-ra20actc	95	23	(	(	-LRB-
cord-329515-ra20actc	95	24	AI6	AI6	NNP
cord-329515-ra20actc	95	25	-	-	HYPH
cord-329515-ra20actc	95	26	101	101	CD
cord-329515-ra20actc	95	27	introduced	introduce	VBD
cord-329515-ra20actc	95	28	in	in	IN
cord-329515-ra20actc	95	29	EcoRI	ecori	NN
cord-329515-ra20actc	95	30	site	site	NN
cord-329515-ra20actc	95	31	of	of	IN
cord-329515-ra20actc	95	32	pBKS	pbks	JJ
cord-329515-ra20actc	95	33	)	)	-RRB-
cord-329515-ra20actc	95	34	.	.	.
cord-329515-ra20actc	96	1	Sequencing	sequencing	NN
cord-329515-ra20actc	96	2	and	and	CC
cord-329515-ra20actc	96	3	further	further	JJ
cord-329515-ra20actc	96	4	subcloning	subcloning	NN
cord-329515-ra20actc	96	5	were	be	VBD
cord-329515-ra20actc	96	6	as	as	IN
cord-329515-ra20actc	96	7	described	describe	VBN
cord-329515-ra20actc	96	8	above	above	RB
cord-329515-ra20actc	96	9	.	.	.
cord-329515-ra20actc	97	1	Alternatively	alternatively	RB
cord-329515-ra20actc	97	2	,	,	,
cord-329515-ra20actc	97	3	final	final	JJ
cord-329515-ra20actc	97	4	PCR	PCR	NNP
cord-329515-ra20actc	97	5	products	product	NNS
cord-329515-ra20actc	97	6	were	be	VBD
cord-329515-ra20actc	97	7	directly	directly	RB
cord-329515-ra20actc	97	8	subcloned	subclone	VBN
cord-329515-ra20actc	97	9	into	into	IN
cord-329515-ra20actc	97	10	the	the	DT
cord-329515-ra20actc	97	11	Sinai	Sinai	NNP
cord-329515-ra20actc	97	12	site	site	NN
cord-329515-ra20actc	97	13	of	of	IN
cord-329515-ra20actc	97	14	the	the	DT
cord-329515-ra20actc	97	15	pECE	pece	NN
cord-329515-ra20actc	97	16	vector	vector	NN
cord-329515-ra20actc	97	17	and	and	CC
cord-329515-ra20actc	97	18	sequenced	sequence	VBN
cord-329515-ra20actc	97	19	.	.	.
cord-329515-ra20actc	98	1	For	for	IN
cord-329515-ra20actc	98	2	the	the	DT
cord-329515-ra20actc	98	3	construction	construction	NN
cord-329515-ra20actc	98	4	of	of	IN
cord-329515-ra20actc	98	5	the	the	DT
cord-329515-ra20actc	98	6	A24	A24	NNP
cord-329515-ra20actc	98	7	-	-	HYPH
cord-329515-ra20actc	98	8	101	101	CD
cord-329515-ra20actc	98	9	mutant	mutant	NN
cord-329515-ra20actc	98	10	(	(	-LRB-
cord-329515-ra20actc	98	11	p63	p63	CD
cord-329515-ra20actc	98	12	with	with	IN
cord-329515-ra20actc	98	13	a	a	DT
cord-329515-ra20actc	98	14	deletion	deletion	NN
cord-329515-ra20actc	98	15	of	of	IN
cord-329515-ra20actc	98	16	amino	amino	JJ
cord-329515-ra20actc	98	17	acids	acid	NNS
cord-329515-ra20actc	98	18	24	24	CD
cord-329515-ra20actc	98	19	to	to	IN
cord-329515-ra20actc	98	20	101	101	CD
cord-329515-ra20actc	98	21	)	)	-RRB-
cord-329515-ra20actc	98	22	,	,	,
cord-329515-ra20actc	98	23	pBKS	pbks	JJ
cord-329515-ra20actc	98	24	-	-	HYPH
cord-329515-ra20actc	98	25	p63	p63	CD
cord-329515-ra20actc	98	26	A16	A16	NNP
cord-329515-ra20actc	98	27	-	-	HYPH
cord-329515-ra20actc	98	28	101	101	NNP
cord-329515-ra20actc	98	29	was	be	VBD
cord-329515-ra20actc	98	30	used	use	VBN
cord-329515-ra20actc	98	31	as	as	IN
cord-329515-ra20actc	98	32	PCR	PCR	NNP
cord-329515-ra20actc	98	33	template	template	NN
cord-329515-ra20actc	98	34	.	.	.
cord-329515-ra20actc	99	1	The	the	DT
cord-329515-ra20actc	99	2	internal	internal	JJ
cord-329515-ra20actc	99	3	primers	primer	NNS
cord-329515-ra20actc	99	4	were	be	VBD
cord-329515-ra20actc	99	5	GCC	GCC	NNP
cord-329515-ra20actc	99	6	GCG	GCG	NNP
cord-329515-ra20actc	99	7	AGC	AGC	NNP
cord-329515-ra20actc	99	8	CCC	CCC	NNP
cord-329515-ra20actc	99	9	TCG	TCG	NNP
cord-329515-ra20actc	99	10	GAG	GAG	NNP
cord-329515-ra20actc	99	11	AAG	AAG	NNP
cord-329515-ra20actc	99	12	GGT	GGT	NNP
cord-329515-ra20actc	99	13	GCC	GCC	NNP
cord-329515-ra20actc	99	14	CGC	CGC	NNP
cord-329515-ra20actc	99	15	AGG	AGG	NNP
cord-329515-ra20actc	99	16	CTC	CTC	NNP
cord-329515-ra20actc	99	17	GC~	GC~	NNP
cord-329515-ra20actc	100	1	AGG	AGG	NNP
cord-329515-ra20actc	100	2	GCG	GCG	NNP
cord-329515-ra20actc	100	3	CTC	CTC	NNP
cord-329515-ra20actc	100	4	AAC	aac	NN
cord-329515-ra20actc	100	5	TTT	TTT	NNP
cord-329515-ra20actc	100	6	for	for	IN
cord-329515-ra20actc	100	7	the	the	DT
cord-329515-ra20actc	100	8	downstream	downstream	JJ
cord-329515-ra20actc	100	9	reaction	reaction	NN
cord-329515-ra20actc	100	10	and	and	CC
cord-329515-ra20actc	100	11	GCG	GCG	NNP
cord-329515-ra20actc	100	12	OC~	OC~	NNP
cord-329515-ra20actc	101	1	ACC	ACC	NNP
cord-329515-ra20actc	101	2	CTT	CTT	NNP
cord-329515-ra20actc	101	3	CTC	CTC	NNP
cord-329515-ra20actc	101	4	CGA	CGA	NNP
cord-329515-ra20actc	101	5	GGG	GGG	NNP
cord-329515-ra20actc	101	6	G	G	NNP
cord-329515-ra20actc	101	7	-	-	HYPH
cord-329515-ra20actc	101	8	CT	CT	NNP
cord-329515-ra20actc	101	9	CGC	CGC	NNP
cord-329515-ra20actc	101	10	~	~	NFP
cord-329515-ra20actc	101	11	GCC	gcc	NN
cord-329515-ra20actc	101	12	GTG	GTG	NNP
cord-329515-ra20actc	101	13	GCC	gcc	NN
cord-329515-ra20actc	101	14	GCC	gcc	NN
cord-329515-ra20actc	101	15	CTT	CTT	NNP
cord-329515-ra20actc	101	16	GGA	GGA	NNP
cord-329515-ra20actc	101	17	GCC	GCC	NNP
cord-329515-ra20actc	101	18	CCT	CCT	NNP
cord-329515-ra20actc	101	19	for	for	IN
cord-329515-ra20actc	101	20	the	the	DT
cord-329515-ra20actc	101	21	upstream	upstream	JJ
cord-329515-ra20actc	101	22	reaction	reaction	NN
cord-329515-ra20actc	101	23	,	,	,
cord-329515-ra20actc	101	24	respectively	respectively	RB
cord-329515-ra20actc	101	25	.	.	.
cord-329515-ra20actc	102	1	The	the	DT
cord-329515-ra20actc	102	2	final	final	JJ
cord-329515-ra20actc	102	3	plasmid	plasmid	NN
cord-329515-ra20actc	102	4	was	be	VBD
cord-329515-ra20actc	102	5	designated	designate	VBN
cord-329515-ra20actc	102	6	pECE	pece	NN
cord-329515-ra20actc	102	7	-	-	HYPH
cord-329515-ra20actc	102	8	A24	A24	NNP
cord-329515-ra20actc	102	9	-	-	HYPH
cord-329515-ra20actc	102	10	101	101	CD
cord-329515-ra20actc	102	11	.	.	.
cord-329515-ra20actc	103	1	Alanine	alanine	JJ
cord-329515-ra20actc	103	2	replacements	replacement	NNS
cord-329515-ra20actc	103	3	of	of	IN
cord-329515-ra20actc	103	4	seven	seven	CD
cord-329515-ra20actc	103	5	consecutive	consecutive	JJ
cord-329515-ra20actc	103	6	amino	amino	NN
cord-329515-ra20actc	103	7	acids	acid	NNS
cord-329515-ra20actc	103	8	in	in	IN
cord-329515-ra20actc	103	9	the	the	DT
cord-329515-ra20actc	103	10	p63	p63	CD
cord-329515-ra20actc	103	11	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	103	12	tail	tail	NN
cord-329515-ra20actc	103	13	were	be	VBD
cord-329515-ra20actc	103	14	encoded	encode	VBN
cord-329515-ra20actc	103	15	by	by	IN
cord-329515-ra20actc	103	16	GCT	GCT	NNP
cord-329515-ra20actc	103	17	GCA	GCA	NNP
cord-329515-ra20actc	103	18	GCC	GCC	NNP
cord-329515-ra20actc	103	19	GCA	GCA	NNP
cord-329515-ra20actc	103	20	GCT	GCT	NNP
cord-329515-ra20actc	103	21	GCA	GCA	NNP
cord-329515-ra20actc	103	22	GCC	GCC	NNP
cord-329515-ra20actc	103	23	and	and	CC
cord-329515-ra20actc	103	24	its	-PRON-	PRP$
cord-329515-ra20actc	103	25	complementary	complementary	JJ
cord-329515-ra20actc	103	26	sequence	sequence	NN
cord-329515-ra20actc	103	27	.	.	.
cord-329515-ra20actc	104	1	For	for	IN
cord-329515-ra20actc	104	2	the	the	DT
cord-329515-ra20actc	104	3	substitution	substitution	NN
cord-329515-ra20actc	104	4	of	of	IN
cord-329515-ra20actc	104	5	positively	positively	RB
cord-329515-ra20actc	104	6	charged	charge	VBN
cord-329515-ra20actc	104	7	amino	amino	NN
cord-329515-ra20actc	104	8	acids	acid	NNS
cord-329515-ra20actc	104	9	and/or	and/or	CC
cord-329515-ra20actc	104	10	glycines	glycine	NNS
cord-329515-ra20actc	104	11	within	within	IN
cord-329515-ra20actc	104	12	amino	amino	NN
cord-329515-ra20actc	104	13	acids	acid	NNS
cord-329515-ra20actc	104	14	1	1	CD
cord-329515-ra20actc	104	15	-	-	SYM
cord-329515-ra20actc	104	16	23	23	CD
cord-329515-ra20actc	104	17	of	of	IN
cord-329515-ra20actc	104	18	the	the	DT
cord-329515-ra20actc	104	19	p63	p63	CD
cord-329515-ra20actc	104	20	sequence	sequence	NN
cord-329515-ra20actc	104	21	by	by	IN
cord-329515-ra20actc	104	22	alanines	alanine	NNS
cord-329515-ra20actc	104	23	,	,	,
cord-329515-ra20actc	104	24	the	the	DT
cord-329515-ra20actc	104	25	following	follow	VBG
cord-329515-ra20actc	104	26	codons	codon	NNS
cord-329515-ra20actc	104	27	were	be	VBD
cord-329515-ra20actc	104	28	used	use	VBN
cord-329515-ra20actc	104	29	:	:	:
cord-329515-ra20actc	104	30	GCA	GCA	NNP
cord-329515-ra20actc	104	31	(	(	-LRB-
cord-329515-ra20actc	104	32	for	for	IN
cord-329515-ra20actc	104	33	amino	amino	JJ
cord-329515-ra20actc	104	34	acids	acid	NNS
cord-329515-ra20actc	104	35	5	5	CD
cord-329515-ra20actc	104	36	,	,	,
cord-329515-ra20actc	104	37	7	7	CD
cord-329515-ra20actc	104	38	,	,	,
cord-329515-ra20actc	104	39	and	and	CC
cord-329515-ra20actc	104	40	21	21	CD
cord-329515-ra20actc	104	41	)	)	-RRB-
cord-329515-ra20actc	104	42	and	and	CC
cord-329515-ra20actc	104	43	GCT	GCT	NNP
cord-329515-ra20actc	104	44	(	(	-LRB-
cord-329515-ra20actc	104	45	for	for	IN
cord-329515-ra20actc	104	46	amino	amino	JJ
cord-329515-ra20actc	104	47	acids	acid	NNS
cord-329515-ra20actc	104	48	8	8	CD
cord-329515-ra20actc	104	49	,	,	,
cord-329515-ra20actc	104	50	10	10	CD
cord-329515-ra20actc	104	51	,	,	,
cord-329515-ra20actc	104	52	11	11	CD
cord-329515-ra20actc	104	53	,	,	,
cord-329515-ra20actc	104	54	and	and	CC
cord-329515-ra20actc	104	55	22	22	CD
cord-329515-ra20actc	104	56	)	)	-RRB-
cord-329515-ra20actc	104	57	.	.	.
cord-329515-ra20actc	105	1	To	to	TO
cord-329515-ra20actc	105	2	construct	construct	VB
cord-329515-ra20actc	105	3	fusion	fusion	NN
cord-329515-ra20actc	105	4	genes	gene	NNS
cord-329515-ra20actc	105	5	of	of	IN
cord-329515-ra20actc	105	6	p63	p63	NN
cord-329515-ra20actc	105	7	and	and	CC
cord-329515-ra20actc	105	8	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	105	9	IV	IV	NNP
cord-329515-ra20actc	105	10	(	(	-LRB-
cord-329515-ra20actc	105	11	DPPIV	DPPIV	NNP
cord-329515-ra20actc	105	12	)	)	-RRB-
cord-329515-ra20actc	105	13	,	,	,
cord-329515-ra20actc	105	14	a	a	DT
cord-329515-ra20actc	105	15	cDNA	cdna	NN
cord-329515-ra20actc	105	16	for	for	IN
cord-329515-ra20actc	105	17	human	human	JJ
cord-329515-ra20actc	105	18	DPPIV	DPPIV	NNP
cord-329515-ra20actc	106	1	(	(	-LRB-
cord-329515-ra20actc	106	2	Misumi	Misumi	NNP
cord-329515-ra20actc	106	3	et	et	NNP
cord-329515-ra20actc	106	4	ai	ai	NNP
cord-329515-ra20actc	106	5	.	.	NNP
cord-329515-ra20actc	106	6	,	,	,
cord-329515-ra20actc	106	7	1992	1992	CD
cord-329515-ra20actc	106	8	;	;	:
cord-329515-ra20actc	106	9	 	 	_SP
cord-329515-ra20actc	106	10	kindly	kindly	RB
cord-329515-ra20actc	106	11	provided	provide	VBN
cord-329515-ra20actc	106	12	by	by	IN
cord-329515-ra20actc	106	13	Dr.	Dr.	NNP
cord-329515-ra20actc	106	14	Y.	Y.	NNP
cord-329515-ra20actc	106	15	Ikehara	Ikehara	NNP
cord-329515-ra20actc	107	1	[	[	-LRB-
cord-329515-ra20actc	107	2	Fukuoka	Fukuoka	NNP
cord-329515-ra20actc	107	3	University	University	NNP
cord-329515-ra20actc	107	4	,	,	,
cord-329515-ra20actc	107	5	Fukuoka	Fukuoka	NNP
cord-329515-ra20actc	107	6	,	,	,
cord-329515-ra20actc	107	7	Japan	Japan	NNP
cord-329515-ra20actc	107	8	]	]	-RRB-
cord-329515-ra20actc	107	9	)	)	-RRB-
cord-329515-ra20actc	107	10	was	be	VBD
cord-329515-ra20actc	107	11	used	use	VBN
cord-329515-ra20actc	107	12	.	.	.
cord-329515-ra20actc	108	1	For	for	IN
cord-329515-ra20actc	108	2	the	the	DT
cord-329515-ra20actc	108	3	generation	generation	NN
cord-329515-ra20actc	108	4	of	of	IN
cord-329515-ra20actc	108	5	the	the	DT
cord-329515-ra20actc	108	6	PPD	PPD	NNP
cord-329515-ra20actc	108	7	and	and	CC
cord-329515-ra20actc	108	8	A24	A24	NNP
cord-329515-ra20actc	108	9	-	-	HYPH
cord-329515-ra20actc	108	10	101PPD	101ppd	CD
cord-329515-ra20actc	108	11	chimeras	chimera	NNS
cord-329515-ra20actc	108	12	(	(	-LRB-
cord-329515-ra20actc	108	13	complete	complete	JJ
cord-329515-ra20actc	108	14	or	or	CC
cord-329515-ra20actc	108	15	A24	A24	NNP
cord-329515-ra20actc	108	16	-	-	HYPH
cord-329515-ra20actc	108	17	101	101	CD
cord-329515-ra20actc	108	18	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	108	19	tail	tail	NN
cord-329515-ra20actc	108	20	of	of	IN
cord-329515-ra20actc	108	21	1)63	1)63	NNP
cord-329515-ra20actc	108	22	,	,	,
cord-329515-ra20actc	108	23	transmembrane	transmembrane	NN
cord-329515-ra20actc	108	24	domain	domain	NN
cord-329515-ra20actc	108	25	of	of	IN
cord-329515-ra20actc	108	26	p63	p63	CD
cord-329515-ra20actc	108	27	,	,	,
cord-329515-ra20actc	108	28	and	and	CC
cord-329515-ra20actc	108	29	lumenal	lumenal	JJ
cord-329515-ra20actc	108	30	domain	domain	NN
cord-329515-ra20actc	108	31	of	of	IN
cord-329515-ra20actc	108	32	DPPIV	DPPIV	NNP
cord-329515-ra20actc	108	33	)	)	-RRB-
cord-329515-ra20actc	108	34	,	,	,
cord-329515-ra20actc	108	35	the	the	DT
cord-329515-ra20actc	108	36	DPPIV	DPPIV	NNP
cord-329515-ra20actc	108	37	cDNA	cdna	NN
cord-329515-ra20actc	108	38	was	be	VBD
cord-329515-ra20actc	108	39	subcloned	subclone	VBN
cord-329515-ra20actc	108	40	into	into	IN
cord-329515-ra20actc	108	41	a	a	DT
cord-329515-ra20actc	108	42	Bluescript	Bluescript	NNP
cord-329515-ra20actc	108	43	SK	SK	NNP
cord-329515-ra20actc	108	44	-	-	HYPH
cord-329515-ra20actc	108	45	vector	vector	NN
cord-329515-ra20actc	108	46	that	that	WDT
cord-329515-ra20actc	108	47	has	have	VBZ
cord-329515-ra20actc	108	48	the	the	DT
cord-329515-ra20actc	108	49	KpnI	KpnI	NNP
cord-329515-ra20actc	108	50	site	site	NN
cord-329515-ra20actc	108	51	in	in	IN
cord-329515-ra20actc	108	52	its	-PRON-	PRP$
cord-329515-ra20actc	108	53	polylinker	polylinker	NN
cord-329515-ra20actc	108	54	deleted	delete	VBN
cord-329515-ra20actc	108	55	.	.	.
cord-329515-ra20actc	109	1	A	a	DT
cord-329515-ra20actc	109	2	KpnI	KpnI	NNP
cord-329515-ra20actc	109	3	site	site	NN
cord-329515-ra20actc	109	4	was	be	VBD
cord-329515-ra20actc	109	5	then	then	RB
cord-329515-ra20actc	109	6	introduced	introduce	VBN
cord-329515-ra20actc	109	7	between	between	IN
cord-329515-ra20actc	109	8	nucleotides	nucleotide	NNS
cord-329515-ra20actc	109	9	166	166	CD
cord-329515-ra20actc	109	10	and	and	CC
cord-329515-ra20actc	109	11	171	171	CD
cord-329515-ra20actc	109	12	of	of	IN
cord-329515-ra20actc	109	13	the	the	DT
cord-329515-ra20actc	109	14	DPPIV	DPPIV	NNP
cord-329515-ra20actc	109	15	sequence	sequence	NN
cord-329515-ra20actc	109	16	without	without	IN
cord-329515-ra20actc	109	17	altering	alter	VBG
cord-329515-ra20actc	109	18	the	the	DT
cord-329515-ra20actc	109	19	amino	amino	NN
cord-329515-ra20actc	109	20	acid	acid	NN
cord-329515-ra20actc	109	21	sequence	sequence	NN
cord-329515-ra20actc	109	22	.	.	.
cord-329515-ra20actc	110	1	The	the	DT
cord-329515-ra20actc	110	2	resulting	result	VBG
cord-329515-ra20actc	110	3	plasmid	plasmid	NN
cord-329515-ra20actc	110	4	was	be	VBD
cord-329515-ra20actc	110	5	digested	digest	VBN
cord-329515-ra20actc	110	6	with	with	IN
cord-329515-ra20actc	110	7	SalI	SalI	NNP
cord-329515-ra20actc	110	8	and	and	CC
cord-329515-ra20actc	110	9	KpnI	KpnI	NNP
cord-329515-ra20actc	110	10	to	to	TO
cord-329515-ra20actc	110	11	give	give	VB
cord-329515-ra20actc	110	12	a	a	DT
cord-329515-ra20actc	110	13	fragment	fragment	NN
cord-329515-ra20actc	110	14	including	include	VBG
cord-329515-ra20actc	110	15	the	the	DT
cord-329515-ra20actc	110	16	complete	complete	JJ
cord-329515-ra20actc	110	17	lumenal	lumenal	JJ
cord-329515-ra20actc	110	18	domain	domain	NN
cord-329515-ra20actc	110	19	of	of	IN
cord-329515-ra20actc	110	20	DPPIV	DPPIV	NNP
cord-329515-ra20actc	110	21	except	except	IN
cord-329515-ra20actc	110	22	for	for	IN
cord-329515-ra20actc	110	23	the	the	DT
cord-329515-ra20actc	110	24	first	first	JJ
cord-329515-ra20actc	110	25	11	11	CD
cord-329515-ra20actc	110	26	nucleotides	nucleotide	NNS
cord-329515-ra20actc	110	27	(	(	-LRB-
cord-329515-ra20actc	110	28	bp	bp	NNP
cord-329515-ra20actc	110	29	160	160	CD
cord-329515-ra20actc	110	30	-	-	SYM
cord-329515-ra20actc	110	31	170	170	CD
cord-329515-ra20actc	110	32	)	)	-RRB-
cord-329515-ra20actc	110	33	.	.	.
cord-329515-ra20actc	111	1	The	the	DT
cord-329515-ra20actc	111	2	pECE	pece	NN
cord-329515-ra20actc	111	3	-	-	HYPH
cord-329515-ra20actc	111	4	p63	p63	CD
cord-329515-ra20actc	111	5	or	or	CC
cord-329515-ra20actc	111	6	pECE	pece	NN
cord-329515-ra20actc	111	7	-	-	HYPH
cord-329515-ra20actc	111	8	A94	A94	NNP
cord-329515-ra20actc	111	9	-	-	HYPH
cord-329515-ra20actc	111	10	101	101	CD
cord-329515-ra20actc	111	11	plasmid	plasmid	NN
cord-329515-ra20actc	111	12	,	,	,
cord-329515-ra20actc	111	13	respectively	respectively	RB
cord-329515-ra20actc	111	14	,	,	,
cord-329515-ra20actc	111	15	were	be	VBD
cord-329515-ra20actc	111	16	digested	digest	VBN
cord-329515-ra20actc	111	17	with	with	IN
cord-329515-ra20actc	111	18	SalI	SalI	NNP
cord-329515-ra20actc	111	19	and	and	CC
cord-329515-ra20actc	111	20	NotI	NotI	NNP
cord-329515-ra20actc	111	21	,	,	,
cord-329515-ra20actc	111	22	and	and	CC
cord-329515-ra20actc	111	23	the	the	DT
cord-329515-ra20actc	111	24	corresponding	correspond	VBG
cord-329515-ra20actc	111	25	fragments	fragment	NNS
cord-329515-ra20actc	111	26	that	that	WDT
cord-329515-ra20actc	111	27	encode	encode	VBP
cord-329515-ra20actc	111	28	the	the	DT
cord-329515-ra20actc	111	29	complete	complete	JJ
cord-329515-ra20actc	111	30	or	or	CC
cord-329515-ra20actc	111	31	mutant	mutant	JJ
cord-329515-ra20actc	111	32	(	(	-LRB-
cord-329515-ra20actc	111	33	A24	A24	NNP
cord-329515-ra20actc	111	34	-	-	HYPH
cord-329515-ra20actc	111	35	101	101	CD
cord-329515-ra20actc	111	36	)	)	-RRB-
cord-329515-ra20actc	112	1	I)63	I)63	NNP
cord-329515-ra20actc	112	2	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	112	3	tail	tail	NN
cord-329515-ra20actc	112	4	plus	plus	CC
cord-329515-ra20actc	112	5	the	the	DT
cord-329515-ra20actc	112	6	first	first	JJ
cord-329515-ra20actc	112	7	12	12	CD
cord-329515-ra20actc	112	8	amino	amino	NN
cord-329515-ra20actc	112	9	acids	acid	NNS
cord-329515-ra20actc	112	10	of	of	IN
cord-329515-ra20actc	112	11	the	the	DT
cord-329515-ra20actc	112	12	p63	p63	CD
cord-329515-ra20actc	112	13	transmembrane	transmembrane	NN
cord-329515-ra20actc	112	14	domain	domain	NN
cord-329515-ra20actc	112	15	,	,	,
cord-329515-ra20actc	112	16	were	be	VBD
cord-329515-ra20actc	112	17	isolated	isolate	VBN
cord-329515-ra20actc	112	18	.	.	.
cord-329515-ra20actc	113	1	Two	two	CD
cord-329515-ra20actc	113	2	complementary	complementary	JJ
cord-329515-ra20actc	113	3	oligonucleotides	oligonucleotide	NNS
cord-329515-ra20actc	113	4	corresponding	correspond	VBG
cord-329515-ra20actc	113	5	to	to	IN
cord-329515-ra20actc	113	6	nucleotides	nucleotide	NNS
cord-329515-ra20actc	113	7	441	441	CD
cord-329515-ra20actc	113	8	-	-	SYM
cord-329515-ra20actc	113	9	465	465	CD
cord-329515-ra20actc	113	10	of	of	IN
cord-329515-ra20actc	113	11	the	the	DT
cord-329515-ra20actc	113	12	p63	p63	CD
cord-329515-ra20actc	113	13	sequence	sequence	NN
cord-329515-ra20actc	113	14	followed	follow	VBN
cord-329515-ra20actc	113	15	by	by	IN
cord-329515-ra20actc	113	16	nucleotides	nucleotide	NNS
cord-329515-ra20actc	113	17	160	160	CD
cord-329515-ra20actc	113	18	-	-	SYM
cord-329515-ra20actc	113	19	165	165	CD
cord-329515-ra20actc	113	20	of	of	IN
cord-329515-ra20actc	113	21	the	the	DT
cord-329515-ra20actc	113	22	DPPIV	DPPIV	NNP
cord-329515-ra20actc	113	23	sequence	sequence	NN
cord-329515-ra20actc	113	24	and	and	CC
cord-329515-ra20actc	113	25	a	a	DT
cord-329515-ra20actc	113	26	KpnI	KpnI	NNP
cord-329515-ra20actc	113	27	site	site	NN
cord-329515-ra20actc	113	28	were	be	VBD
cord-329515-ra20actc	113	29	sequenced	sequence	VBN
cord-329515-ra20actc	113	30	and	and	CC
cord-329515-ra20actc	113	31	annealed	anneal	VBN
cord-329515-ra20actc	113	32	.	.	.
cord-329515-ra20actc	114	1	These	these	DT
cord-329515-ra20actc	114	2	components	component	NNS
cord-329515-ra20actc	114	3	were	be	VBD
cord-329515-ra20actc	114	4	assembled	assemble	VBN
cord-329515-ra20actc	114	5	in	in	IN
cord-329515-ra20actc	114	6	a	a	DT
cord-329515-ra20actc	114	7	three	three	CD
cord-329515-ra20actc	114	8	-	-	HYPH
cord-329515-ra20actc	114	9	part	part	NN
cord-329515-ra20actc	114	10	ligation	ligation	NN
cord-329515-ra20actc	114	11	to	to	TO
cord-329515-ra20actc	114	12	give	give	VB
cord-329515-ra20actc	114	13	plasmids	plasmid	NNS
cord-329515-ra20actc	114	14	pECE	pece	NN
cord-329515-ra20actc	114	15	-	-	HYPH
cord-329515-ra20actc	114	16	PPD	PPD	NNP
cord-329515-ra20actc	114	17	or	or	CC
cord-329515-ra20actc	114	18	pECE	pece	NN
cord-329515-ra20actc	114	19	-	-	HYPH
cord-329515-ra20actc	114	20	A24	A24	NNP
cord-329515-ra20actc	114	21	-	-	HYPH
cord-329515-ra20actc	114	22	101	101	CD
cord-329515-ra20actc	114	23	PPD	PPD	NNP
cord-329515-ra20actc	114	24	,	,	,
cord-329515-ra20actc	114	25	respectively	respectively	RB
cord-329515-ra20actc	114	26	.	.	.
cord-329515-ra20actc	115	1	All	all	DT
cord-329515-ra20actc	115	2	further	further	JJ
cord-329515-ra20actc	115	3	chimeras	chimera	NNS
cord-329515-ra20actc	115	4	were	be	VBD
cord-329515-ra20actc	115	5	generated	generate	VBN
cord-329515-ra20actc	115	6	by	by	IN
cord-329515-ra20actc	115	7	PCR	PCR	NNP
cord-329515-ra20actc	115	8	using	use	VBG
cord-329515-ra20actc	115	9	the	the	DT
cord-329515-ra20actc	115	10	overlap	overlap	NN
cord-329515-ra20actc	115	11	extension	extension	NN
cord-329515-ra20actc	115	12	technique	technique	NN
cord-329515-ra20actc	115	13	(	(	-LRB-
cord-329515-ra20actc	115	14	Horton	Horton	NNP
cord-329515-ra20actc	115	15	et	et	NNP
cord-329515-ra20actc	115	16	al	al	NNP
cord-329515-ra20actc	115	17	.	.	NNP
cord-329515-ra20actc	115	18	,	,	,
cord-329515-ra20actc	115	19	1989	1989	CD
cord-329515-ra20actc	115	20	)	)	-RRB-
cord-329515-ra20actc	115	21	.	.	.
cord-329515-ra20actc	116	1	All	all	DT
cord-329515-ra20actc	116	2	chimeric	chimeric	JJ
cord-329515-ra20actc	116	3	constructs	construct	NNS
cord-329515-ra20actc	116	4	were	be	VBD
cord-329515-ra20actc	116	5	precisely	precisely	RB
cord-329515-ra20actc	116	6	joined	join	VBN
cord-329515-ra20actc	116	7	at	at	IN
cord-329515-ra20actc	116	8	the	the	DT
cord-329515-ra20actc	116	9	transitions	transition	NNS
cord-329515-ra20actc	116	10	between	between	IN
cord-329515-ra20actc	116	11	two	two	CD
cord-329515-ra20actc	116	12	domains	domain	NNS
cord-329515-ra20actc	116	13	.	.	.
cord-329515-ra20actc	117	1	Final	final	JJ
cord-329515-ra20actc	117	2	PCR	PCR	NNP
cord-329515-ra20actc	117	3	products	product	NNS
cord-329515-ra20actc	117	4	were	be	VBD
cord-329515-ra20actc	117	5	treated	treat	VBN
cord-329515-ra20actc	117	6	as	as	IN
cord-329515-ra20actc	117	7	described	describe	VBN
cord-329515-ra20actc	117	8	above	above	RB
cord-329515-ra20actc	117	9	for	for	IN
cord-329515-ra20actc	117	10	the	the	DT
cord-329515-ra20actc	117	11	p63	p63	CD
cord-329515-ra20actc	117	12	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	117	13	tail	tail	NN
cord-329515-ra20actc	117	14	mutants	mutant	NNS
cord-329515-ra20actc	117	15	,	,	,
cord-329515-ra20actc	117	16	resulting	result	VBG
cord-329515-ra20actc	117	17	in	in	IN
cord-329515-ra20actc	117	18	constructs	construct	NNS
cord-329515-ra20actc	117	19	pECE	pece	NN
cord-329515-ra20actc	117	20	-	-	HYPH
cord-329515-ra20actc	117	21	DDP	DDP	NNP
cord-329515-ra20actc	117	22	(	(	-LRB-
cord-329515-ra20actc	117	23	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	117	24	tail	tail	NN
cord-329515-ra20actc	117	25	of	of	IN
cord-329515-ra20actc	117	26	DPPIV	DPPIV	NNP
cord-329515-ra20actc	117	27	,	,	,
cord-329515-ra20actc	117	28	transmembrane	transmembrane	NN
cord-329515-ra20actc	117	29	domain	domain	NN
cord-329515-ra20actc	117	30	of	of	IN
cord-329515-ra20actc	117	31	DPPIV	DPPIV	NNP
cord-329515-ra20actc	117	32	,	,	,
cord-329515-ra20actc	117	33	and	and	CC
cord-329515-ra20actc	117	34	lumenal	lumenal	JJ
cord-329515-ra20actc	117	35	domain	domain	NN
cord-329515-ra20actc	117	36	of	of	IN
cord-329515-ra20actc	117	37	p63	p63	CD
cord-329515-ra20actc	117	38	)	)	-RRB-
cord-329515-ra20actc	117	39	,	,	,
cord-329515-ra20actc	117	40	pECE	pece	NN
cord-329515-ra20actc	117	41	-	-	HYPH
cord-329515-ra20actc	117	42	DPP	DPP	NNP
cord-329515-ra20actc	117	43	(	(	-LRB-
cord-329515-ra20actc	117	44	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	117	45	tail	tail	NN
cord-329515-ra20actc	117	46	of	of	IN
cord-329515-ra20actc	117	47	DPPIV	DPPIV	NNP
cord-329515-ra20actc	117	48	,	,	,
cord-329515-ra20actc	117	49	transmembrane	transmembrane	NN
cord-329515-ra20actc	117	50	domain	domain	NN
cord-329515-ra20actc	117	51	of	of	IN
cord-329515-ra20actc	117	52	p63	p63	CD
cord-329515-ra20actc	117	53	,	,	,
cord-329515-ra20actc	117	54	and	and	CC
cord-329515-ra20actc	117	55	lumenal	lumenal	JJ
cord-329515-ra20actc	117	56	domain	domain	NN
cord-329515-ra20actc	117	57	of	of	IN
cord-329515-ra20actc	117	58	p63	p63	CD
cord-329515-ra20actc	117	59	)	)	-RRB-
cord-329515-ra20actc	117	60	,	,	,
cord-329515-ra20actc	117	61	and	and	CC
cord-329515-ra20actc	117	62	pECE	pece	NN
cord-329515-ra20actc	117	63	A24	a24	NN
cord-329515-ra20actc	117	64	-	-	HYPH
cord-329515-ra20actc	117	65	101PDP	101pdp	JJ
cord-329515-ra20actc	118	1	(	(	-LRB-
cord-329515-ra20actc	118	2	A24	A24	NNP
cord-329515-ra20actc	118	3	-	-	HYPH
cord-329515-ra20actc	118	4	101	101	CD
cord-329515-ra20actc	118	5	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	118	6	tail	tail	NN
cord-329515-ra20actc	118	7	of	of	IN
cord-329515-ra20actc	118	8	p63	p63	CD
cord-329515-ra20actc	118	9	,	,	,
cord-329515-ra20actc	118	10	transmembrane	transmembrane	NN
cord-329515-ra20actc	118	11	domain	domain	NN
cord-329515-ra20actc	118	12	of	of	IN
cord-329515-ra20actc	118	13	DPPIV	DPPIV	NNP
cord-329515-ra20actc	118	14	,	,	,
cord-329515-ra20actc	118	15	and	and	CC
cord-329515-ra20actc	118	16	lumenal	lumenal	JJ
cord-329515-ra20actc	118	17	domain	domain	NN
cord-329515-ra20actc	118	18	of	of	IN
cord-329515-ra20actc	118	19	p63	p63	CD
cord-329515-ra20actc	118	20	)	)	-RRB-
cord-329515-ra20actc	118	21	,	,	,
cord-329515-ra20actc	118	22	respectively	respectively	RB
cord-329515-ra20actc	118	23	.	.	.
cord-329515-ra20actc	119	1	The	the	DT
cord-329515-ra20actc	119	2	following	following	JJ
cord-329515-ra20actc	119	3	templates	template	NNS
cord-329515-ra20actc	119	4	were	be	VBD
cord-329515-ra20actc	119	5	used	use	VBN
cord-329515-ra20actc	119	6	for	for	IN
cord-329515-ra20actc	119	7	the	the	DT
cord-329515-ra20actc	119	8	PCR	PCR	NNP
cord-329515-ra20actc	119	9	reactions	reaction	NNS
cord-329515-ra20actc	119	10	:	:	:
cord-329515-ra20actc	119	11	plasmids	plasmid	NNS
cord-329515-ra20actc	119	12	pBSK	pBSK	NNP
cord-329515-ra20actc	119	13	-	-	HYPH
cord-329515-ra20actc	119	14	p63	p63	NN
cord-329515-ra20actc	119	15	and	and	CC
cord-329515-ra20actc	119	16	pBSK	pbsk	JJ
cord-329515-ra20actc	119	17	-	-	HYPH
cord-329515-ra20actc	119	18	DPPIV	dppiv	NN
cord-329515-ra20actc	119	19	(	(	-LRB-
cord-329515-ra20actc	119	20	DPPIV	DPPIV	NNP
cord-329515-ra20actc	119	21	cDNA	cdna	NN
cord-329515-ra20actc	119	22	subcloned	subclone	VBN
cord-329515-ra20actc	119	23	as	as	IN
cord-329515-ra20actc	119	24	EcoRI	ecori	NN
cord-329515-ra20actc	119	25	fragment	fragment	NN
cord-329515-ra20actc	119	26	into	into	IN
cord-329515-ra20actc	119	27	the	the	DT
cord-329515-ra20actc	119	28	Bluescript	Bluescript	NNP
cord-329515-ra20actc	119	29	KS	KS	NNP
cord-329515-ra20actc	119	30	-	-	HYPH
cord-329515-ra20actc	119	31	vector	vector	NN
cord-329515-ra20actc	119	32	)	)	-RRB-
cord-329515-ra20actc	119	33	to	to	TO
cord-329515-ra20actc	119	34	generate	generate	VB
cord-329515-ra20actc	119	35	constructs	construct	NNS
cord-329515-ra20actc	119	36	DPP	DPP	NNP
cord-329515-ra20actc	119	37	and	and	CC
cord-329515-ra20actc	119	38	DDP	DDP	NNP
cord-329515-ra20actc	119	39	,	,	,
cord-329515-ra20actc	119	40	and	and	CC
cord-329515-ra20actc	119	41	plasmids	plasmid	NNS
cord-329515-ra20actc	119	42	pBKS	pbks	IN
cord-329515-ra20actc	119	43	I)63	I)63	NNP
cord-329515-ra20actc	119	44	A2.4	A2.4	NNP
cord-329515-ra20actc	119	45	-	-	HYPH
cord-329515-ra20actc	119	46	101	101	CD
cord-329515-ra20actc	119	47	and	and	CC
cord-329515-ra20actc	119	48	pECE	pece	NN
cord-329515-ra20actc	119	49	-	-	HYPH
cord-329515-ra20actc	119	50	DDP	DDP	NNP
cord-329515-ra20actc	119	51	to	to	TO
cord-329515-ra20actc	119	52	construct	construct	VB
cord-329515-ra20actc	119	53	the	the	DT
cord-329515-ra20actc	119	54	A94	A94	NNP
cord-329515-ra20actc	119	55	-	-	HYPH
cord-329515-ra20actc	119	56	101PDP	101pdp	CD
cord-329515-ra20actc	119	57	chimera	chimera	NN
cord-329515-ra20actc	119	58	.	.	.
cord-329515-ra20actc	120	1	Upstream	upstream	JJ
cord-329515-ra20actc	120	2	and	and	CC
cord-329515-ra20actc	120	3	downstream	downstream	JJ
cord-329515-ra20actc	120	4	flanking	flanking	JJ
cord-329515-ra20actc	120	5	primers	primer	NNS
cord-329515-ra20actc	120	6	were	be	VBD
cord-329515-ra20actc	120	7	the	the	DT
cord-329515-ra20actc	120	8	same	same	JJ
cord-329515-ra20actc	120	9	as	as	IN
cord-329515-ra20actc	120	10	above	above	RB
cord-329515-ra20actc	120	11	.	.	.
cord-329515-ra20actc	121	1	Appropriate	appropriate	JJ
cord-329515-ra20actc	121	2	pairs	pair	NNS
cord-329515-ra20actc	121	3	of	of	IN
cord-329515-ra20actc	121	4	partially	partially	RB
cord-329515-ra20actc	121	5	complementary	complementary	JJ
cord-329515-ra20actc	121	6	oligonucleotides	oligonucleotide	NNS
cord-329515-ra20actc	121	7	which	which	WDT
cord-329515-ra20actc	121	8	encoded	encode	VBD
cord-329515-ra20actc	121	9	the	the	DT
cord-329515-ra20actc	121	10	desired	desire	VBN
cord-329515-ra20actc	121	11	fusion	fusion	NN
cord-329515-ra20actc	121	12	were	be	VBD
cord-329515-ra20actc	121	13	chosen	choose	VBN
cord-329515-ra20actc	121	14	as	as	IN
cord-329515-ra20actc	121	15	internal	internal	JJ
cord-329515-ra20actc	121	16	primers	primer	NNS
cord-329515-ra20actc	121	17	.	.	.
cord-329515-ra20actc	122	1	All	all	DT
cord-329515-ra20actc	122	2	mutants	mutant	NNS
cord-329515-ra20actc	122	3	were	be	VBD
cord-329515-ra20actc	122	4	verified	verify	VBN
cord-329515-ra20actc	122	5	by	by	IN
cord-329515-ra20actc	122	6	sequencing	sequence	VBG
cord-329515-ra20actc	122	7	at	at	IN
cord-329515-ra20actc	122	8	the	the	DT
cord-329515-ra20actc	122	9	level	level	NN
cord-329515-ra20actc	122	10	of	of	IN
cord-329515-ra20actc	122	11	the	the	DT
cord-329515-ra20actc	122	12	final	final	JJ
cord-329515-ra20actc	122	13	plasmid	plasmid	NN
cord-329515-ra20actc	122	14	.	.	.
cord-329515-ra20actc	123	1	COS	COS	NNP
cord-329515-ra20actc	123	2	cells	cell	NNS
cord-329515-ra20actc	123	3	(	(	-LRB-
cord-329515-ra20actc	123	4	African	african	JJ
cord-329515-ra20actc	123	5	green	green	JJ
cord-329515-ra20actc	123	6	monkey	monkey	NN
cord-329515-ra20actc	123	7	kidney	kidney	NN
cord-329515-ra20actc	123	8	cells	cell	NNS
cord-329515-ra20actc	123	9	,	,	,
cord-329515-ra20actc	123	10	CRL	CRL	NNP
cord-329515-ra20actc	123	11	1650	1650	CD
cord-329515-ra20actc	123	12	;	;	:
cord-329515-ra20actc	123	13	American	American	NNP
cord-329515-ra20actc	123	14	Type	Type	NNP
cord-329515-ra20actc	123	15	Culture	Culture	NNP
cord-329515-ra20actc	123	16	Collection	Collection	NNP
cord-329515-ra20actc	123	17	,	,	,
cord-329515-ra20actc	123	18	Rockville	Rockville	NNP
cord-329515-ra20actc	123	19	,	,	,
cord-329515-ra20actc	123	20	MD	MD	NNP
cord-329515-ra20actc	123	21	)	)	-RRB-
cord-329515-ra20actc	123	22	were	be	VBD
cord-329515-ra20actc	123	23	cultured	culture	VBN
cord-329515-ra20actc	123	24	in	in	IN
cord-329515-ra20actc	123	25	DME	DME	NNP
cord-329515-ra20actc	123	26	supplemented	supplement	VBN
cord-329515-ra20actc	123	27	with	with	IN
cord-329515-ra20actc	123	28	10	10	CD
cord-329515-ra20actc	123	29	%	%	NN
cord-329515-ra20actc	123	30	FCS	FCS	NNP
cord-329515-ra20actc	123	31	,	,	,
cord-329515-ra20actc	123	32	50	50	CD
cord-329515-ra20actc	123	33	units	unit	NNS
cord-329515-ra20actc	123	34	/	/	SYM
cord-329515-ra20actc	123	35	ml	ml	NN
cord-329515-ra20actc	123	36	penicillin	penicillin	NN
cord-329515-ra20actc	123	37	,	,	,
cord-329515-ra20actc	123	38	50	50	CD
cord-329515-ra20actc	123	39	t	t	NN
cord-329515-ra20actc	123	40	~	~	CD
cord-329515-ra20actc	123	41	g	g	NN
cord-329515-ra20actc	123	42	/	/	SYM
cord-329515-ra20actc	123	43	ml	ml	NN
cord-329515-ra20actc	123	44	streptomycin	streptomycin	NN
cord-329515-ra20actc	123	45	,	,	,
cord-329515-ra20actc	123	46	and	and	CC
cord-329515-ra20actc	123	47	fungizone	fungizone	NN
cord-329515-ra20actc	123	48	at	at	IN
cord-329515-ra20actc	123	49	37	37	CD
cord-329515-ra20actc	123	50	°	°	NN
cord-329515-ra20actc	123	51	C	c	NN
cord-329515-ra20actc	123	52	in	in	IN
cord-329515-ra20actc	123	53	a	a	DT
cord-329515-ra20actc	123	54	humidified	humidify	VBN
cord-329515-ra20actc	123	55	5	5	CD
cord-329515-ra20actc	123	56	%	%	NN
cord-329515-ra20actc	123	57	CO	co	NN
cord-329515-ra20actc	123	58	:	:	:
cord-329515-ra20actc	123	59	atmosphere	atmosphere	NN
cord-329515-ra20actc	123	60	.	.	.
cord-329515-ra20actc	124	1	For	for	IN
cord-329515-ra20actc	124	2	transient	transient	JJ
cord-329515-ra20actc	124	3	tr	tr	NN
cord-329515-ra20actc	124	4	~	~	NFP
cord-329515-ra20actc	124	5	ons	on	NNS
cord-329515-ra20actc	124	6	COS	cos	NN
cord-329515-ra20actc	124	7	cells	cell	NNS
cord-329515-ra20actc	124	8	were	be	VBD
cord-329515-ra20actc	124	9	plated	plate	VBN
cord-329515-ra20actc	124	10	at	at	IN
cord-329515-ra20actc	124	11	17,500	17,500	CD
cord-329515-ra20actc	124	12	-	-	SYM
cord-329515-ra20actc	124	13	35,000	35,000	CD
cord-329515-ra20actc	124	14	cells	cell	NNS
cord-329515-ra20actc	124	15	per	per	IN
cord-329515-ra20actc	124	16	well	well	RB
cord-329515-ra20actc	124	17	in	in	IN
cord-329515-ra20actc	124	18	an	an	DT
cord-329515-ra20actc	124	19	eight	eight	CD
cord-329515-ra20actc	124	20	-	-	HYPH
cord-329515-ra20actc	124	21	well	well	RB
cord-329515-ra20actc	124	22	multichamber	multichamber	NN
cord-329515-ra20actc	124	23	slide	slide	NN
cord-329515-ra20actc	124	24	in	in	IN
cord-329515-ra20actc	124	25	which	which	WDT
cord-329515-ra20actc	124	26	the	the	DT
cord-329515-ra20actc	124	27	wells	well	NNS
cord-329515-ra20actc	124	28	had	have	VBD
cord-329515-ra20actc	124	29	been	be	VBN
cord-329515-ra20actc	124	30	coated	coat	VBN
cord-329515-ra20actc	124	31	for	for	IN
cord-329515-ra20actc	124	32	at	at	RB
cord-329515-ra20actc	124	33	least	least	RBS
cord-329515-ra20actc	124	34	20	20	CD
cord-329515-ra20actc	124	35	rain	rain	NN
cord-329515-ra20actc	124	36	with	with	IN
cord-329515-ra20actc	124	37	25	25	CD
cord-329515-ra20actc	124	38	tLg	tlg	CD
cord-329515-ra20actc	124	39	/	/	SYM
cord-329515-ra20actc	124	40	ml	ml	IN
cord-329515-ra20actc	124	41	fibronectin	fibronectin	NN
cord-329515-ra20actc	124	42	in	in	IN
cord-329515-ra20actc	124	43	PBS	PBS	NNP
cord-329515-ra20actc	124	44	,	,	,
cord-329515-ra20actc	124	45	or	or	CC
cord-329515-ra20actc	124	46	at	at	IN
cord-329515-ra20actc	124	47	106	106	CD
cord-329515-ra20actc	124	48	cells	cell	NNS
cord-329515-ra20actc	124	49	per	per	IN
cord-329515-ra20actc	124	50	60-mm	60-mm	CD
cord-329515-ra20actc	124	51	plate	plate	NN
cord-329515-ra20actc	124	52	.	.	.
cord-329515-ra20actc	125	1	Suboonfluent	Suboonfluent	NNP
cord-329515-ra20actc	125	2	cells	cell	NNS
cord-329515-ra20actc	125	3	were	be	VBD
cord-329515-ra20actc	125	4	washed	wash	VBN
cord-329515-ra20actc	125	5	once	once	RB
cord-329515-ra20actc	125	6	with	with	IN
cord-329515-ra20actc	125	7	TBS	TBS	NNP
cord-329515-ra20actc	125	8	and	and	CC
cord-329515-ra20actc	125	9	each	each	DT
cord-329515-ra20actc	125	10	60-ram	60-ram	CD
cord-329515-ra20actc	125	11	plate	plate	NN
cord-329515-ra20actc	125	12	was	be	VBD
cord-329515-ra20actc	125	13	exposed	expose	VBN
cord-329515-ra20actc	125	14	to	to	IN
cord-329515-ra20actc	125	15	3/~g	3/~g	CD
cord-329515-ra20actc	125	16	of	of	IN
cord-329515-ra20actc	125	17	DNA	DNA	NNP
cord-329515-ra20actc	125	18	in	in	IN
cord-329515-ra20actc	125	19	1.5	1.5	CD
cord-329515-ra20actc	125	20	ml	ml	NN
cord-329515-ra20actc	125	21	RPMI-1640	rpmi-1640	NN
cord-329515-ra20actc	125	22	medium	medium	NN
cord-329515-ra20actc	125	23	containing	contain	VBG
cord-329515-ra20actc	125	24	10	10	CD
cord-329515-ra20actc	125	25	%	%	NN
cord-329515-ra20actc	125	26	Nnsera	Nnsera	NNP
cord-329515-ra20actc	125	27	,	,	,
cord-329515-ra20actc	125	28	50	50	CD
cord-329515-ra20actc	125	29	t	t	NN
cord-329515-ra20actc	125	30	~	~	CD
cord-329515-ra20actc	125	31	g	g	NN
cord-329515-ra20actc	125	32	/	/	SYM
cord-329515-ra20actc	125	33	ml	ml	NN
cord-329515-ra20actc	125	34	gentumycin	gentumycin	NNP
cord-329515-ra20actc	125	35	,	,	,
cord-329515-ra20actc	125	36	100	100	CD
cord-329515-ra20actc	125	37	t	t	NN
cord-329515-ra20actc	125	38	~	~	CD
cord-329515-ra20actc	125	39	M	M	NNP
cord-329515-ra20actc	125	40	ehloroquiue	ehloroquiue	NN
cord-329515-ra20actc	125	41	,	,	,
cord-329515-ra20actc	125	42	and	and	CC
cord-329515-ra20actc	125	43	150/~g	150/~g	CD
cord-329515-ra20actc	125	44	/	/	SYM
cord-329515-ra20actc	125	45	ml	ml	NN
cord-329515-ra20actc	125	46	DEAE	DEAE	NNP
cord-329515-ra20actc	125	47	-	-	HYPH
cord-329515-ra20actc	125	48	dextran	dextran	NN
cord-329515-ra20actc	125	49	(	(	-LRB-
cord-329515-ra20actc	125	50	RNC	RNC	NNP
cord-329515-ra20actc	125	51	plus	plus	CC
cord-329515-ra20actc	125	52	DEAE	DEAE	NNP
cord-329515-ra20actc	125	53	-	-	HYPH
cord-329515-ra20actc	125	54	dextran	dextran	NN
cord-329515-ra20actc	125	55	)	)	-RRB-
cord-329515-ra20actc	125	56	for	for	IN
cord-329515-ra20actc	125	57	3.5	3.5	CD
cord-329515-ra20actc	125	58	h.	h.	NN
cord-329515-ra20actc	125	59	For	for	IN
cord-329515-ra20actc	125	60	eightwell	eightwell	JJ
cord-329515-ra20actc	125	61	multichamber	multichamber	NNP
cord-329515-ra20actc	126	1	slides	slide	NNS
cord-329515-ra20actc	126	2	0.2/~g	0.2/~g	-RRB-
cord-329515-ra20actc	126	3	DNA	DNA	NNP
cord-329515-ra20actc	126	4	in	in	IN
cord-329515-ra20actc	126	5	100/~1	100/~1	CD
cord-329515-ra20actc	127	1	RNC	RNC	NNP
cord-329515-ra20actc	127	2	plus	plus	CC
cord-329515-ra20actc	127	3	DEAE	DEAE	NNP
cord-329515-ra20actc	127	4	-	-	HYPH
cord-329515-ra20actc	127	5	dextran	dextran	NN
cord-329515-ra20actc	127	6	was	be	VBD
cord-329515-ra20actc	127	7	used	use	VBN
cord-329515-ra20actc	127	8	in	in	IN
cord-329515-ra20actc	127	9	each	each	DT
cord-329515-ra20actc	127	10	well	well	NN
cord-329515-ra20actc	127	11	.	.	.
cord-329515-ra20actc	128	1	The	the	DT
cord-329515-ra20actc	128	2	DNA	dna	NN
cord-329515-ra20actc	128	3	solution	solution	NN
cord-329515-ra20actc	128	4	was	be	VBD
cord-329515-ra20actc	128	5	then	then	RB
cord-329515-ra20actc	128	6	replaced	replace	VBN
cord-329515-ra20actc	128	7	with	with	IN
cord-329515-ra20actc	128	8	PBS	PBS	NNP
cord-329515-ra20actc	128	9	containing	contain	VBG
cord-329515-ra20actc	128	10	10	10	CD
cord-329515-ra20actc	128	11	%	%	NN
cord-329515-ra20actc	128	12	DMSO	DMSO	NNP
cord-329515-ra20actc	128	13	,	,	,
cord-329515-ra20actc	128	14	cells	cell	NNS
cord-329515-ra20actc	128	15	were	be	VBD
cord-329515-ra20actc	128	16	incubated	incubate	VBN
cord-329515-ra20actc	128	17	for	for	IN
cord-329515-ra20actc	128	18	2	2	CD
cord-329515-ra20actc	128	19	rain	rain	NN
cord-329515-ra20actc	128	20	at	at	IN
cord-329515-ra20actc	128	21	room	room	NN
cord-329515-ra20actc	128	22	temperature	temperature	NN
cord-329515-ra20actc	128	23	,	,	,
cord-329515-ra20actc	128	24	and	and	CC
cord-329515-ra20actc	128	25	washed	wash	VBD
cord-329515-ra20actc	128	26	with	with	IN
cord-329515-ra20actc	128	27	PBS	PBS	NNP
cord-329515-ra20actc	128	28	before	before	IN
cord-329515-ra20actc	128	29	fresh	fresh	JJ
cord-329515-ra20actc	128	30	medium	medium	NN
cord-329515-ra20actc	128	31	was	be	VBD
cord-329515-ra20actc	128	32	added	add	VBN
cord-329515-ra20actc	128	33	.	.	.
cord-329515-ra20actc	129	1	Cells	cell	NNS
cord-329515-ra20actc	129	2	were	be	VBD
cord-329515-ra20actc	129	3	maintained	maintain	VBN
cord-329515-ra20actc	129	4	at	at	IN
cord-329515-ra20actc	129	5	37"C	37"c	CD
cord-329515-ra20actc	129	6	and	and	CC
cord-329515-ra20actc	129	7	analyzed	analyze	VBD
cord-329515-ra20actc	129	8	43	43	CD
cord-329515-ra20actc	129	9	-	-	SYM
cord-329515-ra20actc	129	10	48	48	CD
cord-329515-ra20actc	129	11	h	h	NN
cord-329515-ra20actc	129	12	after	after	IN
cord-329515-ra20actc	129	13	transfection	transfection	NN
cord-329515-ra20actc	129	14	.	.	.
cord-329515-ra20actc	130	1	Mouse	Mouse	NNP
cord-329515-ra20actc	130	2	mAb	mAb	NNP
cord-329515-ra20actc	130	3	G1/296	G1/296	NNP
cord-329515-ra20actc	130	4	against	against	IN
cord-329515-ra20actc	130	5	the	the	DT
cord-329515-ra20actc	130	6	p63	p63	NNP
cord-329515-ra20actc	130	7	protein	protein	NN
cord-329515-ra20actc	130	8	has	have	VBZ
cord-329515-ra20actc	130	9	previously	previously	RB
cord-329515-ra20actc	130	10	been	be	VBN
cord-329515-ra20actc	130	11	characterized	characterize	VBN
cord-329515-ra20actc	131	1	(	(	-LRB-
cord-329515-ra20actc	131	2	Schweizer	Schweizer	NNP
cord-329515-ra20actc	131	3	et	et	NNP
cord-329515-ra20actc	131	4	ai	ai	NNP
cord-329515-ra20actc	131	5	.	.	NNP
cord-329515-ra20actc	131	6	,	,	,
cord-329515-ra20actc	131	7	1993a	1993a	CD
cord-329515-ra20actc	131	8	)	)	-RRB-
cord-329515-ra20actc	131	9	.	.	.
cord-329515-ra20actc	132	1	For	for	IN
cord-329515-ra20actc	132	2	the	the	DT
cord-329515-ra20actc	132	3	detection	detection	NN
cord-329515-ra20actc	132	4	of	of	IN
cord-329515-ra20actc	132	5	DPPIV	DPPIV	NNP
cord-329515-ra20actc	132	6	rnAb	rnAb	NNP
cord-329515-ra20actc	132	7	HBB	HBB	NNP
cord-329515-ra20actc	132	8	3/775	3/775	CD
cord-329515-ra20actc	132	9	(	(	-LRB-
cord-329515-ra20actc	132	10	Hauri	Hauri	NNP
cord-329515-ra20actc	132	11	et	et	NNP
cord-329515-ra20actc	132	12	al	al	NNP
cord-329515-ra20actc	132	13	.	.	NNP
cord-329515-ra20actc	132	14	,	,	,
cord-329515-ra20actc	132	15	1985	1985	CD
cord-329515-ra20actc	132	16	)	)	-RRB-
cord-329515-ra20actc	132	17	was	be	VBD
cord-329515-ra20actc	132	18	used	use	VBN
cord-329515-ra20actc	132	19	.	.	.
cord-329515-ra20actc	133	1	cos	cos	NNP
cord-329515-ra20actc	133	2	cells	cell	NNS
cord-329515-ra20actc	133	3	were	be	VBD
cord-329515-ra20actc	133	4	grown	grow	VBN
cord-329515-ra20actc	133	5	in	in	IN
cord-329515-ra20actc	133	6	eight	eight	CD
cord-329515-ra20actc	133	7	-	-	HYPH
cord-329515-ra20actc	133	8	well	well	JJ
cord-329515-ra20actc	133	9	multichamber	multichamber	NN
cord-329515-ra20actc	133	10	slides	slide	NNS
cord-329515-ra20actc	133	11	.	.	.
cord-329515-ra20actc	134	1	The	the	DT
cord-329515-ra20actc	134	2	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	134	3	procedure	procedure	NN
cord-329515-ra20actc	134	4	for	for	IN
cord-329515-ra20actc	134	5	permeabilized	permeabilized	JJ
cord-329515-ra20actc	134	6	cells	cell	NNS
cord-329515-ra20actc	134	7	was	be	VBD
cord-329515-ra20actc	134	8	that	that	DT
cord-329515-ra20actc	134	9	of	of	IN
cord-329515-ra20actc	134	10	Schweizer	Schweizer	NNP
cord-329515-ra20actc	134	11	et	et	NNP
cord-329515-ra20actc	134	12	al	al	NNP
cord-329515-ra20actc	134	13	.	.	.
cord-329515-ra20actc	135	1	(	(	-LRB-
cord-329515-ra20actc	135	2	1988	1988	CD
cord-329515-ra20actc	135	3	)	)	-RRB-
cord-329515-ra20actc	135	4	.	.	.
cord-329515-ra20actc	136	1	In	in	IN
cord-329515-ra20actc	136	2	brief	brief	JJ
cord-329515-ra20actc	136	3	,	,	,
cord-329515-ra20actc	136	4	formaldehyde	formaldehyde	NN
cord-329515-ra20actc	136	5	-	-	HYPH
cord-329515-ra20actc	136	6	fixed	fix	VBN
cord-329515-ra20actc	136	7	and	and	CC
cord-329515-ra20actc	136	8	sapenin	sapenin	NNS
cord-329515-ra20actc	136	9	-	-	HYPH
cord-329515-ra20actc	136	10	permeabilized	permeabilize	VBN
cord-329515-ra20actc	136	11	cells	cell	NNS
cord-329515-ra20actc	136	12	were	be	VBD
cord-329515-ra20actc	136	13	incubated	incubate	VBN
cord-329515-ra20actc	136	14	with	with	IN
cord-329515-ra20actc	136	15	mAb	mAb	NNP
cord-329515-ra20actc	136	16	G1/296	G1/296	NNP
cord-329515-ra20actc	136	17	against	against	IN
cord-329515-ra20actc	136	18	p63	p63	CD
cord-329515-ra20actc	136	19	or	or	CC
cord-329515-ra20actc	136	20	rnAb	rnab	NN
cord-329515-ra20actc	136	21	HBB	HBB	NNP
cord-329515-ra20actc	136	22	3/775	3/775	CD
cord-329515-ra20actc	136	23	against	against	IN
cord-329515-ra20actc	136	24	DPPIV	DPPIV	NNP
cord-329515-ra20actc	136	25	followed	follow	VBN
cord-329515-ra20actc	136	26	by	by	IN
cord-329515-ra20actc	136	27	goat	goat	NN
cord-329515-ra20actc	136	28	anti	anti	JJ
cord-329515-ra20actc	136	29	-	-	JJ
cord-329515-ra20actc	136	30	mouse	mouse	JJ
cord-329515-ra20actc	136	31	FITC	FITC	NNP
cord-329515-ra20actc	136	32	.	.	.
cord-329515-ra20actc	137	1	To	to	TO
cord-329515-ra20actc	137	2	probe	probe	VB
cord-329515-ra20actc	137	3	for	for	IN
cord-329515-ra20actc	137	4	surface	surface	NN
cord-329515-ra20actc	137	5	expression	expression	NN
cord-329515-ra20actc	137	6	of	of	IN
cord-329515-ra20actc	137	7	proteins	protein	NNS
cord-329515-ra20actc	137	8	,	,	,
cord-329515-ra20actc	137	9	COS	cos	NN
cord-329515-ra20actc	137	10	cells	cell	NNS
cord-329515-ra20actc	137	11	were	be	VBD
cord-329515-ra20actc	137	12	cooled	cool	VBN
cord-329515-ra20actc	137	13	to	to	IN
cord-329515-ra20actc	137	14	4	4	CD
cord-329515-ra20actc	137	15	°	°	NN
cord-329515-ra20actc	137	16	C	c	NN
cord-329515-ra20actc	137	17	for	for	IN
cord-329515-ra20actc	137	18	20	20	CD
cord-329515-ra20actc	137	19	rain	rain	NN
cord-329515-ra20actc	137	20	and	and	CC
cord-329515-ra20actc	137	21	kept	keep	VBD
cord-329515-ra20actc	137	22	on	on	IN
cord-329515-ra20actc	137	23	ice	ice	NN
cord-329515-ra20actc	137	24	for	for	IN
cord-329515-ra20actc	137	25	the	the	DT
cord-329515-ra20actc	137	26	subsequent	subsequent	JJ
cord-329515-ra20actc	137	27	steps	step	NNS
cord-329515-ra20actc	137	28	.	.	.
cord-329515-ra20actc	138	1	The	the	DT
cord-329515-ra20actc	138	2	cells	cell	NNS
cord-329515-ra20actc	138	3	were	be	VBD
cord-329515-ra20actc	138	4	washed	wash	VBN
cord-329515-ra20actc	138	5	once	once	RB
cord-329515-ra20actc	138	6	with	with	IN
cord-329515-ra20actc	138	7	PBS-0.2	PBS-0.2	NNP
cord-329515-ra20actc	138	8	%	%	NN
cord-329515-ra20actc	138	9	BSA	BSA	NNP
cord-329515-ra20actc	138	10	,	,	,
cord-329515-ra20actc	138	11	and	and	CC
cord-329515-ra20actc	138	12	incubated	incubate	VBN
cord-329515-ra20actc	138	13	with	with	IN
cord-329515-ra20actc	138	14	mAb	mab	JJ
cord-329515-ra20actc	138	15	G1/296	G1/296	NNP
cord-329515-ra20actc	138	16	or	or	CC
cord-329515-ra20actc	138	17	mAb	mAb	NNP
cord-329515-ra20actc	138	18	HBB	HBB	NNP
cord-329515-ra20actc	138	19	3/775	3/775	CD
cord-329515-ra20actc	138	20	for	for	IN
cord-329515-ra20actc	138	21	45	45	CD
cord-329515-ra20actc	138	22	rain	rain	NN
cord-329515-ra20actc	138	23	.	.	.
cord-329515-ra20actc	139	1	After	after	IN
cord-329515-ra20actc	139	2	six	six	CD
cord-329515-ra20actc	139	3	wash	wash	NN
cord-329515-ra20actc	139	4	steps	step	NNS
cord-329515-ra20actc	139	5	with	with	IN
cord-329515-ra20actc	139	6	PBS-0.2	PBS-0.2	NNP
cord-329515-ra20actc	139	7	%	%	NN
cord-329515-ra20actc	139	8	BSA	BSA	NNP
cord-329515-ra20actc	139	9	,	,	,
cord-329515-ra20actc	139	10	the	the	DT
cord-329515-ra20actc	139	11	cells	cell	NNS
cord-329515-ra20actc	139	12	were	be	VBD
cord-329515-ra20actc	139	13	fixed	fix	VBN
cord-329515-ra20actc	139	14	with	with	IN
cord-329515-ra20actc	139	15	3	3	CD
cord-329515-ra20actc	139	16	%	%	NN
cord-329515-ra20actc	139	17	p	p	NN
cord-329515-ra20actc	139	18	-	-	HYPH
cord-329515-ra20actc	139	19	formaldehyde	formaldehyde	NN
cord-329515-ra20actc	139	20	for	for	IN
cord-329515-ra20actc	139	21	30	30	CD
cord-329515-ra20actc	139	22	rain	rain	NN
cord-329515-ra20actc	139	23	on	on	IN
cord-329515-ra20actc	139	24	ice	ice	NN
cord-329515-ra20actc	139	25	,	,	,
cord-329515-ra20actc	139	26	followed	follow	VBN
cord-329515-ra20actc	139	27	by	by	IN
cord-329515-ra20actc	139	28	another	another	DT
cord-329515-ra20actc	139	29	30	30	CD
cord-329515-ra20actc	139	30	rain	rain	NN
cord-329515-ra20actc	139	31	at	at	IN
cord-329515-ra20actc	139	32	room	room	NN
cord-329515-ra20actc	139	33	temperature	temperature	NN
cord-329515-ra20actc	139	34	.	.	.
cord-329515-ra20actc	140	1	Cell	cell	NN
cord-329515-ra20actc	140	2	permeabilization	permeabilization	NN
cord-329515-ra20actc	140	3	and	and	CC
cord-329515-ra20actc	140	4	staining	stain	VBG
cord-329515-ra20actc	140	5	with	with	IN
cord-329515-ra20actc	140	6	goat	goat	NN
cord-329515-ra20actc	140	7	anti	anti	JJ
cord-329515-ra20actc	140	8	-	-	JJ
cord-329515-ra20actc	140	9	mouse	mouse	JJ
cord-329515-ra20actc	140	10	FITC	FITC	NNP
cord-329515-ra20actc	140	11	was	be	VBD
cord-329515-ra20actc	140	12	as	as	IN
cord-329515-ra20actc	140	13	described	describe	VBN
cord-329515-ra20actc	141	1	(	(	-LRB-
cord-329515-ra20actc	141	2	Schweizer	Schweizer	NNP
cord-329515-ra20actc	141	3	et	et	NNP
cord-329515-ra20actc	141	4	ai	ai	NNP
cord-329515-ra20actc	141	5	.	.	NNP
cord-329515-ra20actc	141	6	,	,	,
cord-329515-ra20actc	141	7	1988	1988	CD
cord-329515-ra20actc	141	8	)	)	-RRB-
cord-329515-ra20actc	141	9	.	.	.
cord-329515-ra20actc	142	1	The	the	DT
cord-329515-ra20actc	142	2	specimens	specimen	NNS
cord-329515-ra20actc	142	3	were	be	VBD
cord-329515-ra20actc	142	4	examined	examine	VBN
cord-329515-ra20actc	142	5	with	with	IN
cord-329515-ra20actc	142	6	a	a	DT
cord-329515-ra20actc	142	7	Nikon	Nikon	NNP
cord-329515-ra20actc	142	8	fluorescence	fluorescence	NN
cord-329515-ra20actc	142	9	microscope	microscope	NN
cord-329515-ra20actc	142	10	and	and	CC
cord-329515-ra20actc	142	11	photographed	photograph	VBN
cord-329515-ra20actc	142	12	with	with	IN
cord-329515-ra20actc	142	13	1600	1600	CD
cord-329515-ra20actc	142	14	Fujichrome	Fujichrome	NNP
cord-329515-ra20actc	142	15	film	film	NN
cord-329515-ra20actc	142	16	.	.	.
cord-329515-ra20actc	143	1	After	after	IN
cord-329515-ra20actc	143	2	two	two	CD
cord-329515-ra20actc	143	3	washes	wash	NNS
cord-329515-ra20actc	143	4	with	with	IN
cord-329515-ra20actc	143	5	PBS	PBS	NNP
cord-329515-ra20actc	143	6	,	,	,
cord-329515-ra20actc	143	7	transfectod	transfectod	NNP
cord-329515-ra20actc	143	8	COS	COS	NNP
cord-329515-ra20actc	143	9	cells	cell	NNS
cord-329515-ra20actc	143	10	of	of	IN
cord-329515-ra20actc	143	11	one	one	CD
cord-329515-ra20actc	143	12	60-ram	60-ram	CD
cord-329515-ra20actc	143	13	plate	plate	NN
cord-329515-ra20actc	143	14	were	be	VBD
cord-329515-ra20actc	143	15	scraped	scrape	VBN
cord-329515-ra20actc	143	16	into	into	IN
cord-329515-ra20actc	143	17	1	1	CD
cord-329515-ra20actc	143	18	ml	ml	NN
cord-329515-ra20actc	143	19	PBS	PBS	NNP
cord-329515-ra20actc	143	20	and	and	CC
cord-329515-ra20actc	143	21	centrifuged	centrifuge	VBN
cord-329515-ra20actc	143	22	for	for	IN
cord-329515-ra20actc	143	23	10	10	CD
cord-329515-ra20actc	143	24	rain	rain	NN
cord-329515-ra20actc	143	25	at	at	IN
cord-329515-ra20actc	143	26	800	800	CD
cord-329515-ra20actc	143	27	rpm	rpm	NN
cord-329515-ra20actc	143	28	(	(	-LRB-
cord-329515-ra20actc	143	29	132	132	CD
cord-329515-ra20actc	143	30	giv	giv	NN
cord-329515-ra20actc	143	31	)	)	-RRB-
cord-329515-ra20actc	143	32	.	.	.
cord-329515-ra20actc	144	1	The	the	DT
cord-329515-ra20actc	144	2	pellet	pellet	NN
cord-329515-ra20actc	144	3	was	be	VBD
cord-329515-ra20actc	144	4	resuspended	resuspend	VBN
cord-329515-ra20actc	144	5	in	in	IN
cord-329515-ra20actc	144	6	800/~1	800/~1	NNP
cord-329515-ra20actc	145	1	MNT	MNT	NNP
cord-329515-ra20actc	145	2	buffer	buffer	NN
cord-329515-ra20actc	145	3	(	(	-LRB-
cord-329515-ra20actc	145	4	20	20	CD
cord-329515-ra20actc	145	5	m_M	m_m	JJ
cord-329515-ra20actc	145	6	MES	mes	NN
cord-329515-ra20actc	145	7	,	,	,
cord-329515-ra20actc	145	8	30	30	CD
cord-329515-ra20actc	145	9	mM	mm	CD
cord-329515-ra20actc	145	10	Tris	Tris	NNP
cord-329515-ra20actc	145	11	,	,	,
cord-329515-ra20actc	145	12	100	100	CD
cord-329515-ra20actc	145	13	mM	mm	CD
cord-329515-ra20actc	145	14	NaCl	nacl	NN
cord-329515-ra20actc	145	15	,	,	,
cord-329515-ra20actc	145	16	1.25	1.25	CD
cord-329515-ra20actc	145	17	m_M	m_m	JJ
cord-329515-ra20actc	145	18	EDTA	edta	NN
cord-329515-ra20actc	145	19	,	,	,
cord-329515-ra20actc	145	20	and	and	CC
cord-329515-ra20actc	145	21	1	1	CD
cord-329515-ra20actc	145	22	mM	mm	CD
cord-329515-ra20actc	145	23	EGTA	EGTA	NNP
cord-329515-ra20actc	145	24	)	)	-RRB-
cord-329515-ra20actc	145	25	at	at	IN
cord-329515-ra20actc	145	26	various	various	JJ
cord-329515-ra20actc	145	27	pHs	pHs	NNP
cord-329515-ra20actc	145	28	containing	contain	VBG
cord-329515-ra20actc	145	29	1	1	CD
cord-329515-ra20actc	145	30	%	%	NN
cord-329515-ra20actc	145	31	Triton	Triton	NNP
cord-329515-ra20actc	145	32	X-100	x-100	NN
cord-329515-ra20actc	145	33	,	,	,
cord-329515-ra20actc	145	34	100	100	CD
cord-329515-ra20actc	145	35	mM	mm	CD
cord-329515-ra20actc	145	36	iodoacetamide	iodoacetamide	NN
cord-329515-ra20actc	145	37	,	,	,
cord-329515-ra20actc	145	38	40	40	CD
cord-329515-ra20actc	145	39	t	t	NN
cord-329515-ra20actc	145	40	~	~	CD
cord-329515-ra20actc	145	41	g	g	NNP
cord-329515-ra20actc	145	42	/	/	SYM
cord-329515-ra20actc	145	43	mi	mi	NNP
cord-329515-ra20actc	145	44	PMSF	PMSF	NNP
cord-329515-ra20actc	145	45	,	,	,
cord-329515-ra20actc	145	46	and	and	CC
cord-329515-ra20actc	145	47	a	a	DT
cord-329515-ra20actc	145	48	1:500	1:500	CD
cord-329515-ra20actc	145	49	dilution	dilution	NN
cord-329515-ra20actc	145	50	of	of	IN
cord-329515-ra20actc	145	51	a	a	DT
cord-329515-ra20actc	145	52	protease	protease	NN
cord-329515-ra20actc	145	53	inhibitor	inhibitor	NN
cord-329515-ra20actc	145	54	cocktail	cocktail	NN
cord-329515-ra20actc	145	55	(	(	-LRB-
cord-329515-ra20actc	145	56	5	5	CD
cord-329515-ra20actc	145	57	mg	mg	NNP
cord-329515-ra20actc	145	58	/	/	SYM
cord-329515-ra20actc	145	59	mi	mi	NNP
cord-329515-ra20actc	145	60	benzamidine	benzamidine	NNP
cord-329515-ra20actc	145	61	and	and	CC
cord-329515-ra20actc	145	62	1	1	CD
cord-329515-ra20actc	145	63	mg	mg	NNP
cord-329515-ra20actc	145	64	/	/	SYM
cord-329515-ra20actc	145	65	ml	ml	XX
cord-329515-ra20actc	145	66	each	each	DT
cord-329515-ra20actc	145	67	of	of	IN
cord-329515-ra20actc	145	68	pepstatin	pepstatin	NNP
cord-329515-ra20actc	145	69	A	A	NNP
cord-329515-ra20actc	145	70	,	,	,
cord-329515-ra20actc	145	71	leupeptin	leupeptin	NN
cord-329515-ra20actc	145	72	,	,	,
cord-329515-ra20actc	145	73	antipain	antipain	NNP
cord-329515-ra20actc	145	74	,	,	,
cord-329515-ra20actc	145	75	and	and	CC
cord-329515-ra20actc	145	76	chymostatin	chymostatin	NN
cord-329515-ra20actc	145	77	in	in	IN
cord-329515-ra20actc	145	78	40	40	CD
cord-329515-ra20actc	145	79	%	%	NN
cord-329515-ra20actc	145	80	dimedaylsnifoxide	dimedaylsnifoxide	NN
cord-329515-ra20actc	145	81	,	,	,
cord-329515-ra20actc	145	82	60	60	CD
cord-329515-ra20actc	145	83	%	%	NN
cord-329515-ra20actc	145	84	ethanol	ethanol	NN
cord-329515-ra20actc	145	85	)	)	-RRB-
cord-329515-ra20actc	145	86	by	by	IN
cord-329515-ra20actc	145	87	passing	pass	VBG
cord-329515-ra20actc	145	88	it	-PRON-	PRP
cord-329515-ra20actc	145	89	five	five	CD
cord-329515-ra20actc	145	90	times	time	NNS
cord-329515-ra20actc	145	91	through	through	IN
cord-329515-ra20actc	145	92	a	a	DT
cord-329515-ra20actc	145	93	25-gange	25-gange	CD
cord-329515-ra20actc	145	94	needle	needle	NN
cord-329515-ra20actc	145	95	connected	connect	VBN
cord-329515-ra20actc	145	96	to	to	IN
cord-329515-ra20actc	145	97	a	a	DT
cord-329515-ra20actc	145	98	1-ml	1-ml	CD
cord-329515-ra20actc	145	99	syringe	syringe	NN
cord-329515-ra20actc	145	100	.	.	.
cord-329515-ra20actc	146	1	After	after	IN
cord-329515-ra20actc	146	2	a	a	DT
cord-329515-ra20actc	146	3	1-h	1-h	CD
cord-329515-ra20actc	146	4	solubilization	solubilization	NN
cord-329515-ra20actc	146	5	step	step	NN
cord-329515-ra20actc	146	6	on	on	IN
cord-329515-ra20actc	146	7	ice	ice	NN
cord-329515-ra20actc	146	8	,	,	,
cord-329515-ra20actc	146	9	the	the	DT
cord-329515-ra20actc	146	10	cells	cell	NNS
cord-329515-ra20actc	146	11	were	be	VBD
cord-329515-ra20actc	146	12	centrifuged	centrifuge	VBN
cord-329515-ra20actc	146	13	for	for	IN
cord-329515-ra20actc	146	14	60	60	CD
cord-329515-ra20actc	146	15	rain	rain	NN
cord-329515-ra20actc	146	16	at	at	IN
cord-329515-ra20actc	146	17	39,000	39,000	CD
cord-329515-ra20actc	146	18	rpm	rpm	NN
cord-329515-ra20actc	146	19	(	(	-LRB-
cord-329515-ra20actc	146	20	100,000	100,000	CD
cord-329515-ra20actc	146	21	g	g	NN
cord-329515-ra20actc	146	22	~	~	CD
cord-329515-ra20actc	146	23	v	v	LS
cord-329515-ra20actc	146	24	)	)	-RRB-
cord-329515-ra20actc	146	25	in	in	IN
cord-329515-ra20actc	146	26	a	a	DT
cord-329515-ra20actc	146	27	Ti	Ti	NNP
cord-329515-ra20actc	146	28	50	50	CD
cord-329515-ra20actc	146	29	rotor	rotor	NN
cord-329515-ra20actc	146	30	(	(	-LRB-
cord-329515-ra20actc	146	31	Beckman	Beckman	NNP
cord-329515-ra20actc	146	32	Instnmaents	Instnmaents	NNP
cord-329515-ra20actc	146	33	Inc.	Inc.	NNP
cord-329515-ra20actc	146	34	,	,	,
cord-329515-ra20actc	146	35	Paio	Paio	NNP
cord-329515-ra20actc	146	36	Alto	Alto	NNP
cord-329515-ra20actc	146	37	,	,	,
cord-329515-ra20actc	146	38	CA	CA	NNP
cord-329515-ra20actc	146	39	)	)	-RRB-
cord-329515-ra20actc	146	40	.	.	.
cord-329515-ra20actc	147	1	The	the	DT
cord-329515-ra20actc	147	2	resulting	result	VBG
cord-329515-ra20actc	147	3	supernatants	supernatant	NNS
cord-329515-ra20actc	147	4	were	be	VBD
cord-329515-ra20actc	147	5	carefully	carefully	RB
cord-329515-ra20actc	147	6	harvested	harvest	VBN
cord-329515-ra20actc	147	7	and	and	CC
cord-329515-ra20actc	147	8	proteins	protein	NNS
cord-329515-ra20actc	147	9	were	be	VBD
cord-329515-ra20actc	147	10	precipitated	precipitate	VBN
cord-329515-ra20actc	147	11	by	by	IN
cord-329515-ra20actc	147	12	the	the	DT
cord-329515-ra20actc	147	13	method	method	NN
cord-329515-ra20actc	147	14	of	of	IN
cord-329515-ra20actc	147	15	Wessel	Wessel	NNP
cord-329515-ra20actc	147	16	and	and	CC
cord-329515-ra20actc	147	17	Fluegge	Fluegge	NNP
cord-329515-ra20actc	147	18	(	(	-LRB-
cord-329515-ra20actc	147	19	1984	1984	CD
cord-329515-ra20actc	147	20	)	)	-RRB-
cord-329515-ra20actc	147	21	.	.	.
cord-329515-ra20actc	148	1	The	the	DT
cord-329515-ra20actc	148	2	precipitates	precipitate	NNS
cord-329515-ra20actc	148	3	were	be	VBD
cord-329515-ra20actc	148	4	solub'~,ed	solub'~,ed	NNP
cord-329515-ra20actc	148	5	in	in	IN
cord-329515-ra20actc	148	6	Laemmli	Laemmli	NNP
cord-329515-ra20actc	148	7	buffer	buffer	NN
cord-329515-ra20actc	148	8	(	(	-LRB-
cord-329515-ra20actc	148	9	Laemmli	Laemmli	NNP
cord-329515-ra20actc	148	10	,	,	,
cord-329515-ra20actc	148	11	1970	1970	CD
cord-329515-ra20actc	148	12	)	)	-RRB-
cord-329515-ra20actc	148	13	.	.	.
cord-329515-ra20actc	149	1	The	the	DT
cord-329515-ra20actc	149	2	pellets	pellet	NNS
cord-329515-ra20actc	149	3	in	in	IN
cord-329515-ra20actc	149	4	the	the	DT
cord-329515-ra20actc	149	5	Ti	Ti	NNP
cord-329515-ra20actc	149	6	50	50	CD
cord-329515-ra20actc	149	7	tubes	tube	NNS
cord-329515-ra20actc	149	8	following	follow	VBG
cord-329515-ra20actc	149	9	centrifugation	centrifugation	NN
cord-329515-ra20actc	149	10	were	be	VBD
cord-329515-ra20actc	149	11	selubilized	selubilize	VBN
cord-329515-ra20actc	149	12	directly	directly	RB
cord-329515-ra20actc	149	13	in	in	IN
cord-329515-ra20actc	149	14	sample	sample	NN
cord-329515-ra20actc	149	15	buffer	buffer	NN
cord-329515-ra20actc	149	16	and	and	CC
cord-329515-ra20actc	149	17	sonicated	sonicate	VBN
cord-329515-ra20actc	149	18	.	.	.
cord-329515-ra20actc	150	1	Proteins	protein	NNS
cord-329515-ra20actc	150	2	were	be	VBD
cord-329515-ra20actc	150	3	separated	separate	VBN
cord-329515-ra20actc	150	4	on	on	IN
cord-329515-ra20actc	150	5	8	8	CD
cord-329515-ra20actc	150	6	%	%	NN
cord-329515-ra20actc	150	7	SDS	sds	NN
cord-329515-ra20actc	150	8	-	-	HYPH
cord-329515-ra20actc	150	9	polyaerylamide	polyaerylamide	NNP
cord-329515-ra20actc	150	10	minigels	minigel	NNS
cord-329515-ra20actc	150	11	(	(	-LRB-
cord-329515-ra20actc	150	12	Bio	Bio	NNP
cord-329515-ra20actc	150	13	Rad	Rad	NNP
cord-329515-ra20actc	150	14	Laboratories	Laboratories	NNP
cord-329515-ra20actc	150	15	,	,	,
cord-329515-ra20actc	150	16	Richmond	Richmond	NNP
cord-329515-ra20actc	150	17	,	,	,
cord-329515-ra20actc	150	18	CA	CA	NNP
cord-329515-ra20actc	150	19	)	)	-RRB-
cord-329515-ra20actc	150	20	using	use	VBG
cord-329515-ra20actc	150	21	the	the	DT
cord-329515-ra20actc	150	22	Laemmli	Laemmli	NNP
cord-329515-ra20actc	150	23	(	(	-LRB-
cord-329515-ra20actc	150	24	1970	1970	CD
cord-329515-ra20actc	150	25	)	)	-RRB-
cord-329515-ra20actc	150	26	system	system	NN
cord-329515-ra20actc	150	27	,	,	,
cord-329515-ra20actc	150	28	and	and	CC
cord-329515-ra20actc	150	29	transferred	transfer	VBN
cord-329515-ra20actc	150	30	to	to	IN
cord-329515-ra20actc	150	31	nitrocellulose	nitrocellulose	JJ
cord-329515-ra20actc	150	32	membranes	membrane	NNS
cord-329515-ra20actc	150	33	according	accord	VBG
cord-329515-ra20actc	150	34	to	to	IN
cord-329515-ra20actc	150	35	the	the	DT
cord-329515-ra20actc	150	36	method	method	NN
cord-329515-ra20actc	150	37	of	of	IN
cord-329515-ra20actc	150	38	Towbin	Towbin	NNP
cord-329515-ra20actc	150	39	et	et	NNP
cord-329515-ra20actc	150	40	al	al	NNP
cord-329515-ra20actc	150	41	.	.	.
cord-329515-ra20actc	151	1	(	(	-LRB-
cord-329515-ra20actc	151	2	1979	1979	CD
cord-329515-ra20actc	151	3	)	)	-RRB-
cord-329515-ra20actc	151	4	.	.	.
cord-329515-ra20actc	152	1	For	for	IN
cord-329515-ra20actc	152	2	the	the	DT
cord-329515-ra20actc	152	3	immunoreaction	immunoreaction	NN
cord-329515-ra20actc	152	4	,	,	,
cord-329515-ra20actc	152	5	the	the	DT
cord-329515-ra20actc	152	6	nitrocellulose	nitrocellulose	NN
cord-329515-ra20actc	152	7	sheet	sheet	NN
cord-329515-ra20actc	152	8	was	be	VBD
cord-329515-ra20actc	152	9	blocked	block	VBN
cord-329515-ra20actc	152	10	with	with	IN
cord-329515-ra20actc	152	11	3	3	CD
cord-329515-ra20actc	152	12	%	%	NN
cord-329515-ra20actc	152	13	nonfat	nonfat	JJ
cord-329515-ra20actc	152	14	dry	dry	JJ
cord-329515-ra20actc	152	15	milk	milk	NN
cord-329515-ra20actc	152	16	powder	powder	NN
cord-329515-ra20actc	152	17	in	in	IN
cord-329515-ra20actc	152	18	PBS	PBS	NNP
cord-329515-ra20actc	152	19	,	,	,
cord-329515-ra20actc	152	20	incubated	incubate	VBN
cord-329515-ra20actc	152	21	with	with	IN
cord-329515-ra20actc	152	22	mAb	mAb	NNP
cord-329515-ra20actc	152	23	G1/296	G1/296	NNP
cord-329515-ra20actc	152	24	against	against	IN
cord-329515-ra20actc	152	25	p63	p63	CD
cord-329515-ra20actc	152	26	(	(	-LRB-
cord-329515-ra20actc	152	27	diluted	diluted	JJ
cord-329515-ra20actc	152	28	1:5,000	1:5,000	CD
cord-329515-ra20actc	152	29	in	in	IN
cord-329515-ra20actc	152	30	PBS-3	PBS-3	NNPS
cord-329515-ra20actc	152	31	%	%	NN
cord-329515-ra20actc	152	32	powdered	powder	VBN
cord-329515-ra20actc	152	33	milk	milk	NN
cord-329515-ra20actc	152	34	)	)	-RRB-
cord-329515-ra20actc	152	35	followed	follow	VBN
cord-329515-ra20actc	152	36	by	by	IN
cord-329515-ra20actc	152	37	a	a	DT
cord-329515-ra20actc	152	38	horseradish	horseradish	NN
cord-329515-ra20actc	152	39	peroxidase	peroxidase	NN
cord-329515-ra20actc	152	40	-	-	HYPH
cord-329515-ra20actc	152	41	conjugated	conjugate	VBN
cord-329515-ra20actc	152	42	anti	anti	JJ
cord-329515-ra20actc	152	43	-	-	JJ
cord-329515-ra20actc	152	44	mouse	mouse	JJ
cord-329515-ra20actc	152	45	secondary	secondary	JJ
cord-329515-ra20actc	152	46	antibody	antibody	NN
cord-329515-ra20actc	152	47	(	(	-LRB-
cord-329515-ra20actc	152	48	Amersham	Amersham	NNP
cord-329515-ra20actc	152	49	Corp.	Corp.	NNP
cord-329515-ra20actc	152	50	)	)	-RRB-
cord-329515-ra20actc	152	51	.	.	.
cord-329515-ra20actc	153	1	For	for	IN
cord-329515-ra20actc	153	2	development	development	NN
cord-329515-ra20actc	153	3	the	the	DT
cord-329515-ra20actc	153	4	ECL	ECL	NNP
cord-329515-ra20actc	153	5	detection	detection	NN
cord-329515-ra20actc	153	6	system	system	NN
cord-329515-ra20actc	153	7	(	(	-LRB-
cord-329515-ra20actc	153	8	Amersham	Amersham	NNP
cord-329515-ra20actc	153	9	Corp.	Corp.	NNP
cord-329515-ra20actc	153	10	)	)	-RRB-
cord-329515-ra20actc	153	11	was	be	VBD
cord-329515-ra20actc	153	12	used	use	VBN
cord-329515-ra20actc	153	13	according	accord	VBG
cord-329515-ra20actc	153	14	to	to	IN
cord-329515-ra20actc	153	15	the	the	DT
cord-329515-ra20actc	153	16	manufacturer	manufacturer	NN
cord-329515-ra20actc	153	17	's	's	POS
cord-329515-ra20actc	153	18	directions	direction	NNS
cord-329515-ra20actc	153	19	.	.	.
cord-329515-ra20actc	154	1	Quantification	quantification	NN
cord-329515-ra20actc	154	2	of	of	IN
cord-329515-ra20actc	154	3	autoradiograms	autoradiograms	NNP
cord-329515-ra20actc	154	4	was	be	VBD
cord-329515-ra20actc	154	5	carried	carry	VBN
cord-329515-ra20actc	154	6	out	out	RP
cord-329515-ra20actc	154	7	by	by	IN
cord-329515-ra20actc	154	8	means	mean	NNS
cord-329515-ra20actc	154	9	of	of	IN
cord-329515-ra20actc	154	10	a	a	DT
cord-329515-ra20actc	154	11	Molecular	Molecular	NNP
cord-329515-ra20actc	154	12	Dynamics	Dynamics	NNPS
cord-329515-ra20actc	154	13	Personal	Personal	NNP
cord-329515-ra20actc	154	14	Densitometer	Densitometer	NNP
cord-329515-ra20actc	154	15	(	(	-LRB-
cord-329515-ra20actc	154	16	Sunnyvale	Sunnyvale	NNP
cord-329515-ra20actc	154	17	,	,	,
cord-329515-ra20actc	154	18	CA	CA	NNP
cord-329515-ra20actc	154	19	)	)	-RRB-
cord-329515-ra20actc	154	20	.	.	.
cord-329515-ra20actc	155	1	cos	cos	NNP
cord-329515-ra20actc	155	2	cells	cell	NNS
cord-329515-ra20actc	155	3	(	(	-LRB-
cord-329515-ra20actc	155	4	10	10	CD
cord-329515-ra20actc	155	5	-	-	SYM
cord-329515-ra20actc	155	6	12	12	CD
cord-329515-ra20actc	155	7	60-mm	60-mm	CD
cord-329515-ra20actc	155	8	plates	plate	NNS
cord-329515-ra20actc	155	9	per	per	IN
cord-329515-ra20actc	155	10	preparation	preparation	NN
cord-329515-ra20actc	155	11	)	)	-RRB-
cord-329515-ra20actc	155	12	transfected	transfecte	VBN
cord-329515-ra20actc	155	13	with	with	IN
cord-329515-ra20actc	155	14	either	either	DT
cord-329515-ra20actc	155	15	p63wt	p63wt	NNP
cord-329515-ra20actc	155	16	or	or	CC
cord-329515-ra20actc	155	17	A2	A2	NNP
cord-329515-ra20actc	155	18	-	-	HYPH
cord-329515-ra20actc	155	19	101AA	101AA	NNP
cord-329515-ra20actc	155	20	were	be	VBD
cord-329515-ra20actc	155	21	washed	wash	VBN
cord-329515-ra20actc	155	22	twice	twice	RB
cord-329515-ra20actc	155	23	with	with	IN
cord-329515-ra20actc	155	24	PBS	PBS	NNP
cord-329515-ra20actc	155	25	,	,	,
cord-329515-ra20actc	155	26	scraped	scrape	VBD
cord-329515-ra20actc	155	27	into	into	IN
cord-329515-ra20actc	155	28	1	1	CD
cord-329515-ra20actc	155	29	ml	ml	NN
cord-329515-ra20actc	155	30	PBS	PBS	NNP
cord-329515-ra20actc	155	31	per	per	IN
cord-329515-ra20actc	155	32	plate	plate	NN
cord-329515-ra20actc	155	33	and	and	CC
cord-329515-ra20actc	155	34	centrifuged	centrifuge	VBN
cord-329515-ra20actc	155	35	for	for	IN
cord-329515-ra20actc	155	36	10	10	CD
cord-329515-ra20actc	155	37	min	min	NN
cord-329515-ra20actc	155	38	at	at	IN
cord-329515-ra20actc	155	39	800	800	CD
cord-329515-ra20actc	155	40	rpm	rpm	NN
cord-329515-ra20actc	155	41	(	(	-LRB-
cord-329515-ra20actc	155	42	132	132	CD
cord-329515-ra20actc	155	43	ga~	ga~	NNP
cord-329515-ra20actc	155	44	)	)	-RRB-
cord-329515-ra20actc	155	45	.	.	.
cord-329515-ra20actc	156	1	Each	each	DT
cord-329515-ra20actc	156	2	pellet	pellet	NN
cord-329515-ra20actc	156	3	was	be	VBD
cord-329515-ra20actc	156	4	resuspended	resuspend	VBN
cord-329515-ra20actc	156	5	in	in	IN
cord-329515-ra20actc	156	6	500/~1	500/~1	CD
cord-329515-ra20actc	156	7	of	of	IN
cord-329515-ra20actc	156	8	buffer	buffer	NN
cord-329515-ra20actc	156	9	2	2	CD
cord-329515-ra20actc	156	10	(	(	-LRB-
cord-329515-ra20actc	156	11	100	100	CD
cord-329515-ra20actc	156	12	mM	mm	CD
cord-329515-ra20actc	156	13	Na2HPO4	Na2HPO4	NNP
cord-329515-ra20actc	156	14	,	,	,
cord-329515-ra20actc	156	15	pH	pH	NNP
cord-329515-ra20actc	156	16	8.0	8.0	CD
cord-329515-ra20actc	156	17	,	,	,
cord-329515-ra20actc	156	18	1	1	CD
cord-329515-ra20actc	156	19	%	%	NN
cord-329515-ra20actc	156	20	Triton	Triton	NNP
cord-329515-ra20actc	156	21	X-100	x-100	NN
cord-329515-ra20actc	156	22	)	)	-RRB-
cord-329515-ra20actc	156	23	,	,	,
cord-329515-ra20actc	156	24	containing	contain	VBG
cord-329515-ra20actc	156	25	100	100	CD
cord-329515-ra20actc	156	26	mM	mm	CD
cord-329515-ra20actc	156	27	iodoacetamide	iodoacetamide	NN
cord-329515-ra20actc	156	28	,	,	,
cord-329515-ra20actc	156	29	40/~g	40/~g	NNP
cord-329515-ra20actc	156	30	/	/	SYM
cord-329515-ra20actc	156	31	ml	ml	NNP
cord-329515-ra20actc	156	32	PMSF	PMSF	NNP
cord-329515-ra20actc	156	33	,	,	,
cord-329515-ra20actc	156	34	and	and	CC
cord-329515-ra20actc	156	35	a	a	DT
cord-329515-ra20actc	156	36	1:500	1:500	CD
cord-329515-ra20actc	156	37	dilution	dilution	NN
cord-329515-ra20actc	156	38	of	of	IN
cord-329515-ra20actc	156	39	the	the	DT
cord-329515-ra20actc	156	40	above	above	RB
cord-329515-ra20actc	156	41	described	describe	VBN
cord-329515-ra20actc	156	42	protein	protein	NN
cord-329515-ra20actc	156	43	inhibitor	inhibitor	NN
cord-329515-ra20actc	156	44	cocktail	cocktail	NN
cord-329515-ra20actc	156	45	by	by	IN
cord-329515-ra20actc	156	46	passing	pass	VBG
cord-329515-ra20actc	156	47	it	-PRON-	PRP
cord-329515-ra20actc	156	48	five	five	CD
cord-329515-ra20actc	156	49	times	time	NNS
cord-329515-ra20actc	156	50	through	through	IN
cord-329515-ra20actc	156	51	a	a	DT
cord-329515-ra20actc	156	52	25-gang¢	25-gang¢	CD
cord-329515-ra20actc	156	53	needle	needle	NN
cord-329515-ra20actc	156	54	connected	connect	VBN
cord-329515-ra20actc	156	55	to	to	IN
cord-329515-ra20actc	156	56	a	a	DT
cord-329515-ra20actc	156	57	1-ml	1-ml	CD
cord-329515-ra20actc	156	58	syringe	syringe	NN
cord-329515-ra20actc	156	59	.	.	.
cord-329515-ra20actc	157	1	After	after	IN
cord-329515-ra20actc	157	2	a	a	DT
cord-329515-ra20actc	157	3	1-h	1-h	CD
cord-329515-ra20actc	157	4	solub'dization	solub'dization	CD
cord-329515-ra20actc	157	5	step	step	NN
cord-329515-ra20actc	157	6	on	on	IN
cord-329515-ra20actc	157	7	ice	ice	NN
cord-329515-ra20actc	157	8	,	,	,
cord-329515-ra20actc	157	9	the	the	DT
cord-329515-ra20actc	157	10	cells	cell	NNS
cord-329515-ra20actc	157	11	were	be	VBD
cord-329515-ra20actc	157	12	centrifuged	centrifuge	VBN
cord-329515-ra20actc	157	13	for	for	IN
cord-329515-ra20actc	157	14	60	60	CD
cord-329515-ra20actc	157	15	rain	rain	NN
cord-329515-ra20actc	157	16	at	at	IN
cord-329515-ra20actc	157	17	39,000	39,000	CD
cord-329515-ra20actc	157	18	rpm	rpm	NN
cord-329515-ra20actc	157	19	(	(	-LRB-
cord-329515-ra20actc	157	20	100,000	100,000	CD
cord-329515-ra20actc	157	21	gay	gay	NN
cord-329515-ra20actc	157	22	)	)	-RRB-
cord-329515-ra20actc	157	23	in	in	IN
cord-329515-ra20actc	157	24	a	a	DT
cord-329515-ra20actc	157	25	Ti	Ti	NNP
cord-329515-ra20actc	157	26	50	50	CD
cord-329515-ra20actc	157	27	rotor	rotor	NN
cord-329515-ra20actc	157	28	.	.	.
cord-329515-ra20actc	158	1	P63	p63	NN
cord-329515-ra20actc	158	2	proteins	protein	NNS
cord-329515-ra20actc	158	3	were	be	VBD
cord-329515-ra20actc	158	4	affinity	affinity	NN
cord-329515-ra20actc	158	5	purified	purify	VBN
cord-329515-ra20actc	158	6	from	from	IN
cord-329515-ra20actc	158	7	the	the	DT
cord-329515-ra20actc	158	8	resulting	result	VBG
cord-329515-ra20actc	158	9	supernatants	supernatant	NNS
cord-329515-ra20actc	158	10	on	on	IN
cord-329515-ra20actc	158	11	a	a	DT
cord-329515-ra20actc	158	12	column	column	NN
cord-329515-ra20actc	158	13	of	of	IN
cord-329515-ra20actc	158	14	mAb	mAb	NNP
cord-329515-ra20actc	158	15	G1/296	G1/296	NNP
cord-329515-ra20actc	158	16	coupled	couple	VBN
cord-329515-ra20actc	158	17	to	to	IN
cord-329515-ra20actc	158	18	cyanogen	cyanogen	NN
cord-329515-ra20actc	158	19	bromide	bromide	NN
cord-329515-ra20actc	158	20	-	-	HYPH
cord-329515-ra20actc	158	21	activated	activate	VBN
cord-329515-ra20actc	158	22	Sepharose	Sepharose	NNP
cord-329515-ra20actc	158	23	4B.	4b.	CD
cord-329515-ra20actc	158	24	mAb	mAb	NNP
cord-329515-ra20actc	158	25	G1/296	G1/296	NNP
cord-329515-ra20actc	158	26	had	have	VBD
cord-329515-ra20actc	158	27	been	be	VBN
cord-329515-ra20actc	158	28	purified	purify	VBN
cord-329515-ra20actc	158	29	from	from	IN
cord-329515-ra20actc	158	30	culture	culture	NN
cord-329515-ra20actc	158	31	supernatant	supernatant	VBN
cord-329515-ra20actc	158	32	by	by	IN
cord-329515-ra20actc	158	33	ammonium	ammonium	NN
cord-329515-ra20actc	158	34	sulfate	sulfate	NN
cord-329515-ra20actc	158	35	precipitation	precipitation	NN
cord-329515-ra20actc	158	36	(	(	-LRB-
cord-329515-ra20actc	158	37	to	to	IN
cord-329515-ra20actc	158	38	50	50	CD
cord-329515-ra20actc	158	39	%	%	NN
cord-329515-ra20actc	158	40	saturation	saturation	NN
cord-329515-ra20actc	158	41	)	)	-RRB-
cord-329515-ra20actc	158	42	followed	follow	VBN
cord-329515-ra20actc	158	43	by	by	IN
cord-329515-ra20actc	158	44	protein	protein	NN
cord-329515-ra20actc	158	45	A	A	NNP
cord-329515-ra20actc	158	46	-	-	HYPH
cord-329515-ra20actc	158	47	Sepharose	Sepharose	NNP
cord-329515-ra20actc	158	48	chromatography	chromatography	NN
cord-329515-ra20actc	158	49	prior	prior	RB
cord-329515-ra20actc	158	50	to	to	IN
cord-329515-ra20actc	158	51	coupling	coupling	NN
cord-329515-ra20actc	158	52	according	accord	VBG
cord-329515-ra20actc	158	53	to	to	IN
cord-329515-ra20actc	158	54	the	the	DT
cord-329515-ra20actc	158	55	suppliers	supplier	NNS
cord-329515-ra20actc	158	56	instructions	instruction	NNS
cord-329515-ra20actc	158	57	.	.	.
cord-329515-ra20actc	159	1	P63	p63	NN
cord-329515-ra20actc	159	2	proteins	protein	NNS
cord-329515-ra20actc	159	3	were	be	VBD
cord-329515-ra20actc	159	4	eluted	elute	VBN
cord-329515-ra20actc	159	5	with	with	IN
cord-329515-ra20actc	159	6	0.1	0.1	CD
cord-329515-ra20actc	159	7	M	M	NNP
cord-329515-ra20actc	159	8	glycine	glycine	NN
cord-329515-ra20actc	159	9	,	,	,
cord-329515-ra20actc	159	10	pH	pH	NNP
cord-329515-ra20actc	159	11	3.0	3.0	CD
cord-329515-ra20actc	159	12	,	,	,
cord-329515-ra20actc	159	13	0.05	0.05	CD
cord-329515-ra20actc	159	14	%	%	NN
cord-329515-ra20actc	159	15	Triton	Triton	NNP
cord-329515-ra20actc	159	16	X-100	x-100	NN
cord-329515-ra20actc	159	17	,	,	,
cord-329515-ra20actc	159	18	and	and	CC
cord-329515-ra20actc	159	19	immediately	immediately	RB
cord-329515-ra20actc	159	20	adjusted	adjust	VBD
cord-329515-ra20actc	159	21	to	to	IN
cord-329515-ra20actc	159	22	pH	pH	NNP
cord-329515-ra20actc	159	23	8.0	8.0	CD
cord-329515-ra20actc	159	24	with	with	IN
cord-329515-ra20actc	159	25	1	1	CD
cord-329515-ra20actc	159	26	M	M	NNP
cord-329515-ra20actc	159	27	"	"	''
cord-329515-ra20actc	159	28	Iris	Iris	NNP
cord-329515-ra20actc	159	29	base	base	NN
cord-329515-ra20actc	159	30	.	.	.
cord-329515-ra20actc	160	1	After	after	IN
cord-329515-ra20actc	160	2	analysis	analysis	NN
cord-329515-ra20actc	160	3	by	by	IN
cord-329515-ra20actc	160	4	SDS	SDS	NNP
cord-329515-ra20actc	160	5	-	-	HYPH
cord-329515-ra20actc	160	6	PAGE	PAGE	NNP
cord-329515-ra20actc	160	7	,	,	,
cord-329515-ra20actc	160	8	fractions	fraction	NNS
cord-329515-ra20actc	160	9	that	that	WDT
cord-329515-ra20actc	160	10	revealed	reveal	VBD
cord-329515-ra20actc	160	11	a	a	DT
cord-329515-ra20actc	160	12	single	single	JJ
cord-329515-ra20actc	160	13	band	band	NN
cord-329515-ra20actc	160	14	of	of	IN
cord-329515-ra20actc	160	15	appropriate	appropriate	JJ
cord-329515-ra20actc	160	16	size	size	NN
cord-329515-ra20actc	160	17	(	(	-LRB-
cord-329515-ra20actc	160	18	Schweizer	Schweizer	NNP
cord-329515-ra20actc	160	19	,	,	,
cord-329515-ra20actc	160	20	A.	A.	NNP
cord-329515-ra20actc	160	21	,	,	,
cord-329515-ra20actc	160	22	J.	J.	NNP
cord-329515-ra20actc	160	23	Rohrer	Rohrer	NNP
cord-329515-ra20actc	160	24	,	,	,
cord-329515-ra20actc	160	25	and	and	CC
cord-329515-ra20actc	160	26	S.	S.	NNP
cord-329515-ra20actc	160	27	Kornfeld	Kornfeld	NNP
cord-329515-ra20actc	160	28	,	,	,
cord-329515-ra20actc	160	29	unpublished	unpublished	JJ
cord-329515-ra20actc	160	30	data	datum	NNS
cord-329515-ra20actc	160	31	)	)	-RRB-
cord-329515-ra20actc	160	32	were	be	VBD
cord-329515-ra20actc	160	33	pooled	pool	VBN
cord-329515-ra20actc	160	34	and	and	CC
cord-329515-ra20actc	160	35	dialyzed	dialyze	VBN
cord-329515-ra20actc	160	36	against	against	IN
cord-329515-ra20actc	160	37	MNT	MNT	NNP
cord-329515-ra20actc	160	38	buffer	buffer	NN
cord-329515-ra20actc	160	39	,	,	,
cord-329515-ra20actc	160	40	pH	pH	NNP
cord-329515-ra20actc	160	41	8.0	8.0	CD
cord-329515-ra20actc	160	42	,	,	,
cord-329515-ra20actc	160	43	containing	contain	VBG
cord-329515-ra20actc	160	44	0.05	0.05	CD
cord-329515-ra20actc	160	45	%	%	NN
cord-329515-ra20actc	160	46	Triton	Triton	NNP
cord-329515-ra20actc	160	47	X-100	x-100	RB
cord-329515-ra20actc	160	48	.	.	.
cord-329515-ra20actc	161	1	Protein	protein	NN
cord-329515-ra20actc	161	2	was	be	VBD
cord-329515-ra20actc	161	3	determined	determine	VBN
cord-329515-ra20actc	161	4	with	with	IN
cord-329515-ra20actc	161	5	the	the	DT
cord-329515-ra20actc	161	6	micro	micro	NNP
cord-329515-ra20actc	161	7	BCA	BCA	NNP
cord-329515-ra20actc	161	8	protein	protein	NN
cord-329515-ra20actc	161	9	assay	assay	NN
cord-329515-ra20actc	161	10	(	(	-LRB-
cord-329515-ra20actc	161	11	Pierce	Pierce	NNP
cord-329515-ra20actc	161	12	,	,	,
cord-329515-ra20actc	161	13	Rockford	Rockford	NNP
cord-329515-ra20actc	161	14	,	,	,
cord-329515-ra20actc	161	15	IL	IL	NNP
cord-329515-ra20actc	161	16	)	)	-RRB-
cord-329515-ra20actc	161	17	.	.	.
cord-329515-ra20actc	162	1	MNT	MNT	NNP
cord-329515-ra20actc	162	2	buffer	buffer	NN
cord-329515-ra20actc	162	3	,	,	,
cord-329515-ra20actc	162	4	pH	pH	NNP
cord-329515-ra20actc	162	5	8.0	8.0	CD
cord-329515-ra20actc	162	6	,	,	,
cord-329515-ra20actc	162	7	containing	contain	VBG
cord-329515-ra20actc	162	8	1	1	CD
cord-329515-ra20actc	162	9	%	%	NN
cord-329515-ra20actc	162	10	Triton	Triton	NNP
cord-329515-ra20actc	162	11	X-100	x-100	NN
cord-329515-ra20actc	162	12	was	be	VBD
cord-329515-ra20actc	162	13	added	add	VBN
cord-329515-ra20actc	162	14	to	to	IN
cord-329515-ra20actc	162	15	0.75/~g	0.75/~g	CD
cord-329515-ra20actc	162	16	of	of	IN
cord-329515-ra20actc	162	17	purified	purify	VBN
cord-329515-ra20actc	162	18	p63wt	p63wt	NNP
cord-329515-ra20actc	162	19	or	or	CC
cord-329515-ra20actc	162	20	A2	A2	NNP
cord-329515-ra20actc	162	21	-	-	HYPH
cord-329515-ra20actc	162	22	101AA	101AA	NNP
cord-329515-ra20actc	162	23	protein	protein	NN
cord-329515-ra20actc	162	24	to	to	IN
cord-329515-ra20actc	162	25	a	a	DT
cord-329515-ra20actc	162	26	final	final	JJ
cord-329515-ra20actc	162	27	volume	volume	NN
cord-329515-ra20actc	162	28	of	of	IN
cord-329515-ra20actc	162	29	700	700	CD
cord-329515-ra20actc	162	30	td	td	NNP
cord-329515-ra20actc	162	31	before	before	IN
cord-329515-ra20actc	162	32	one	one	CD
cord-329515-ra20actc	162	33	of	of	IN
cord-329515-ra20actc	162	34	three	three	CD
cord-329515-ra20actc	162	35	incubations	incubation	NNS
cord-329515-ra20actc	162	36	was	be	VBD
cord-329515-ra20actc	162	37	carried	carry	VBN
cord-329515-ra20actc	162	38	out	out	RP
cord-329515-ra20actc	162	39	.	.	.
cord-329515-ra20actc	163	1	The	the	DT
cord-329515-ra20actc	163	2	first	first	JJ
cord-329515-ra20actc	163	3	sample	sample	NN
cord-329515-ra20actc	163	4	was	be	VBD
cord-329515-ra20actc	163	5	incubated	incubate	VBN
cord-329515-ra20actc	163	6	for	for	IN
cord-329515-ra20actc	163	7	40	40	CD
cord-329515-ra20actc	163	8	rain	rain	NN
cord-329515-ra20actc	163	9	on	on	IN
cord-329515-ra20actc	163	10	ice	ice	NN
cord-329515-ra20actc	163	11	.	.	.
cord-329515-ra20actc	164	1	The	the	DT
cord-329515-ra20actc	164	2	second	second	JJ
cord-329515-ra20actc	164	3	sample	sample	NN
cord-329515-ra20actc	164	4	was	be	VBD
cord-329515-ra20actc	164	5	brought	bring	VBN
cord-329515-ra20actc	164	6	to	to	IN
cord-329515-ra20actc	164	7	pH	pH	NNP
cord-329515-ra20actc	164	8	5.8	5.8	CD
cord-329515-ra20actc	164	9	by	by	IN
cord-329515-ra20actc	164	10	addition	addition	NN
cord-329515-ra20actc	164	11	of	of	IN
cord-329515-ra20actc	164	12	a	a	DT
cord-329515-ra20actc	164	13	pretitrated	pretitrated	JJ
cord-329515-ra20actc	164	14	volume	volume	NN
cord-329515-ra20actc	164	15	of	of	IN
cord-329515-ra20actc	164	16	1	1	CD
cord-329515-ra20actc	164	17	N	N	NNP
cord-329515-ra20actc	164	18	HC1	HC1	NNP
cord-329515-ra20actc	164	19	and	and	CC
cord-329515-ra20actc	164	20	then	then	RB
cord-329515-ra20actc	164	21	incubated	incubate	VBD
cord-329515-ra20actc	164	22	on	on	IN
cord-329515-ra20actc	164	23	ice	ice	NN
cord-329515-ra20actc	164	24	for	for	IN
cord-329515-ra20actc	164	25	40	40	CD
cord-329515-ra20actc	164	26	min	min	NN
cord-329515-ra20actc	164	27	.	.	.
cord-329515-ra20actc	165	1	The	the	DT
cord-329515-ra20actc	165	2	third	third	JJ
cord-329515-ra20actc	165	3	sample	sample	NN
cord-329515-ra20actc	165	4	was	be	VBD
cord-329515-ra20actc	165	5	shifted	shift	VBN
cord-329515-ra20actc	165	6	to	to	IN
cord-329515-ra20actc	165	7	pH	pH	NNP
cord-329515-ra20actc	165	8	5.8	5.8	CD
cord-329515-ra20actc	165	9	and	and	CC
cord-329515-ra20actc	165	10	incubated	incubate	VBN
cord-329515-ra20actc	165	11	on	on	IN
cord-329515-ra20actc	165	12	ice	ice	NN
cord-329515-ra20actc	165	13	for	for	IN
cord-329515-ra20actc	165	14	40	40	CD
cord-329515-ra20actc	165	15	rain	rain	NN
cord-329515-ra20actc	165	16	;	;	:
cord-329515-ra20actc	165	17	the	the	DT
cord-329515-ra20actc	165	18	pH	pH	NNP
cord-329515-ra20actc	165	19	was	be	VBD
cord-329515-ra20actc	165	20	then	then	RB
cord-329515-ra20actc	165	21	returned	return	VBN
cord-329515-ra20actc	165	22	to	to	IN
cord-329515-ra20actc	165	23	8.0	8.0	CD
cord-329515-ra20actc	165	24	by	by	IN
cord-329515-ra20actc	165	25	addition	addition	NN
cord-329515-ra20actc	165	26	of	of	IN
cord-329515-ra20actc	165	27	a	a	DT
cord-329515-ra20actc	165	28	pretitrated	pretitrated	JJ
cord-329515-ra20actc	165	29	volume	volume	NN
cord-329515-ra20actc	165	30	of	of	IN
cord-329515-ra20actc	165	31	1	1	CD
cord-329515-ra20actc	165	32	N	N	NNP
cord-329515-ra20actc	165	33	NaOH	NaOH	NNP
cord-329515-ra20actc	165	34	followed	follow	VBD
cord-329515-ra20actc	165	35	by	by	IN
cord-329515-ra20actc	165	36	another	another	DT
cord-329515-ra20actc	165	37	40	40	CD
cord-329515-ra20actc	165	38	roan	roan	NN
cord-329515-ra20actc	165	39	on	on	IN
cord-329515-ra20actc	165	40	ice	ice	NN
cord-329515-ra20actc	165	41	.	.	.
cord-329515-ra20actc	166	1	All	all	DT
cord-329515-ra20actc	166	2	samples	sample	NNS
cord-329515-ra20actc	166	3	were	be	VBD
cord-329515-ra20actc	166	4	centrifuged	centrifuge	VBN
cord-329515-ra20actc	166	5	for	for	IN
cord-329515-ra20actc	166	6	60	60	CD
cord-329515-ra20actc	166	7	min	min	NN
cord-329515-ra20actc	166	8	at	at	IN
cord-329515-ra20actc	166	9	39,000	39,000	CD
cord-329515-ra20actc	166	10	rpm	rpm	NN
cord-329515-ra20actc	166	11	(	(	-LRB-
cord-329515-ra20actc	166	12	I00,000	I00,000	NNP
cord-329515-ra20actc	166	13	gay	gay	NNP
cord-329515-ra20actc	166	14	)	)	-RRB-
cord-329515-ra20actc	166	15	in	in	IN
cord-329515-ra20actc	166	16	a	a	DT
cord-329515-ra20actc	166	17	Ti	Ti	NNP
cord-329515-ra20actc	166	18	50	50	CD
cord-329515-ra20actc	166	19	rotor	rotor	NN
cord-329515-ra20actc	166	20	.	.	.
cord-329515-ra20actc	167	1	The	the	DT
cord-329515-ra20actc	167	2	resulting	result	VBG
cord-329515-ra20actc	167	3	supernatant	supernatant	NN
cord-329515-ra20actc	167	4	and	and	CC
cord-329515-ra20actc	167	5	pellet	pellet	NN
cord-329515-ra20actc	167	6	fractions	fraction	NNS
cord-329515-ra20actc	167	7	were	be	VBD
cord-329515-ra20actc	167	8	further	further	RB
cord-329515-ra20actc	167	9	treated	treat	VBN
cord-329515-ra20actc	167	10	as	as	IN
cord-329515-ra20actc	167	11	described	describe	VBN
cord-329515-ra20actc	167	12	under	under	IN
cord-329515-ra20actc	167	13	immunoblotting	immunoblotte	VBG
cord-329515-ra20actc	167	14	.	.	.
cord-329515-ra20actc	168	1	The	the	DT
cord-329515-ra20actc	168	2	endogenous	endogenous	JJ
cord-329515-ra20actc	168	3	p63	p63	CD
cord-329515-ra20actc	168	4	could	could	MD
cord-329515-ra20actc	168	5	be	be	VB
cord-329515-ra20actc	168	6	visualized	visualize	VBN
cord-329515-ra20actc	168	7	in	in	IN
cord-329515-ra20actc	168	8	saponin	saponin	NN
cord-329515-ra20actc	168	9	-	-	HYPH
cord-329515-ra20actc	168	10	permeabilized	permeabilized	JJ
cord-329515-ra20actc	168	11	COS	cos	NN
cord-329515-ra20actc	168	12	cells	cell	NNS
cord-329515-ra20actc	168	13	by	by	IN
cord-329515-ra20actc	168	14	indirect	indirect	JJ
cord-329515-ra20actc	168	15	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	168	16	using	use	VBG
cord-329515-ra20actc	168	17	a	a	DT
cord-329515-ra20actc	168	18	1:20	1:20	CD
cord-329515-ra20actc	168	19	dilution	dilution	NN
cord-329515-ra20actc	168	20	of	of	IN
cord-329515-ra20actc	168	21	mAb	mab	NN
cord-329515-ra20actc	168	22	G1/296	G1/296	NNP
cord-329515-ra20actc	168	23	which	which	WDT
cord-329515-ra20actc	168	24	is	be	VBZ
cord-329515-ra20actc	168	25	specific	specific	JJ
cord-329515-ra20actc	168	26	for	for	IN
cord-329515-ra20actc	168	27	this	this	DT
cord-329515-ra20actc	168	28	protein	protein	NN
cord-329515-ra20actc	168	29	.	.	.
cord-329515-ra20actc	169	1	As	as	IN
cord-329515-ra20actc	169	2	shown	show	VBN
cord-329515-ra20actc	169	3	in	in	IN
cord-329515-ra20actc	169	4	Fig	Fig	NNP
cord-329515-ra20actc	169	5	.	.	.
cord-329515-ra20actc	170	1	1	1	LS
cord-329515-ra20actc	170	2	a	a	DT
cord-329515-ra20actc	170	3	,	,	,
cord-329515-ra20actc	170	4	the	the	DT
cord-329515-ra20actc	170	5	fluorescence	fluorescence	NN
cord-329515-ra20actc	170	6	pattern	pattern	NN
cord-329515-ra20actc	170	7	with	with	IN
cord-329515-ra20actc	170	8	its	-PRON-	PRP$
cord-329515-ra20actc	170	9	extended	extended	JJ
cord-329515-ra20actc	170	10	ER	ER	NNP
cord-329515-ra20actc	170	11	-	-	HYPH
cord-329515-ra20actc	170	12	Golgi	golgi	NN
cord-329515-ra20actc	170	13	intermediate	intermediate	JJ
cord-329515-ra20actc	170	14	membrane	membrane	NN
cord-329515-ra20actc	170	15	structure	structure	NN
cord-329515-ra20actc	170	16	was	be	VBD
cord-329515-ra20actc	170	17	very	very	RB
cord-329515-ra20actc	170	18	similar	similar	JJ
cord-329515-ra20actc	170	19	to	to	IN
cord-329515-ra20actc	171	1	that	that	IN
cord-329515-ra20actc	171	2	observed	observe	VBD
cord-329515-ra20actc	171	3	previously	previously	RB
cord-329515-ra20actc	171	4	with	with	IN
cord-329515-ra20actc	171	5	Vero	Vero	NNP
cord-329515-ra20actc	171	6	cells	cell	NNS
cord-329515-ra20actc	171	7	(	(	-LRB-
cord-329515-ra20actc	172	1	Schweizer	Schweizer	NNP
cord-329515-ra20actc	172	2	et	et	NNP
cord-329515-ra20actc	172	3	al	al	NNP
cord-329515-ra20actc	172	4	.	.	NNP
cord-329515-ra20actc	172	5	,	,	,
cord-329515-ra20actc	172	6	1993a	1993a	CD
cord-329515-ra20actc	172	7	)	)	-RRB-
cord-329515-ra20actc	172	8	.	.	.
cord-329515-ra20actc	173	1	While	while	IN
cord-329515-ra20actc	173	2	ER	ER	NNP
cord-329515-ra20actc	173	3	-	-	HYPH
cord-329515-ra20actc	173	4	like	like	JJ
cord-329515-ra20actc	173	5	,	,	,
cord-329515-ra20actc	173	6	the	the	DT
cord-329515-ra20actc	173	7	pattern	pattern	NN
cord-329515-ra20actc	173	8	differs	differ	VBZ
cord-329515-ra20actc	173	9	from	from	IN
cord-329515-ra20actc	173	10	that	that	DT
cord-329515-ra20actc	173	11	observed	observe	VBN
cord-329515-ra20actc	173	12	with	with	IN
cord-329515-ra20actc	173	13	ER	ER	NNP
cord-329515-ra20actc	173	14	markers	marker	NNS
cord-329515-ra20actc	173	15	in	in	IN
cord-329515-ra20actc	173	16	that	that	IN
cord-329515-ra20actc	173	17	it	-PRON-	PRP
cord-329515-ra20actc	173	18	is	be	VBZ
cord-329515-ra20actc	173	19	less	less	RBR
cord-329515-ra20actc	173	20	reticular	reticular	JJ
cord-329515-ra20actc	173	21	and	and	CC
cord-329515-ra20actc	174	1	the	the	DT
cord-329515-ra20actc	174	2	outer	outer	JJ
cord-329515-ra20actc	174	3	nuclear	nuclear	JJ
cord-329515-ra20actc	174	4	membrane	membrane	NN
cord-329515-ra20actc	174	5	does	do	VBZ
cord-329515-ra20actc	174	6	not	not	RB
cord-329515-ra20actc	174	7	stain	stain	VB
cord-329515-ra20actc	174	8	(	(	-LRB-
cord-329515-ra20actc	174	9	see	see	VB
cord-329515-ra20actc	174	10	Fig	Fig	NNP
cord-329515-ra20actc	174	11	.	.	.
cord-329515-ra20actc	175	1	2	2	LS
cord-329515-ra20actc	175	2	c	c	NN
cord-329515-ra20actc	175	3	for	for	IN
cord-329515-ra20actc	175	4	a	a	DT
cord-329515-ra20actc	175	5	typical	typical	JJ
cord-329515-ra20actc	175	6	ER	er	NN
cord-329515-ra20actc	175	7	pattern	pattern	NN
cord-329515-ra20actc	175	8	and	and	CC
cord-329515-ra20actc	175	9	Schweizer	Schweizer	NNP
cord-329515-ra20actc	175	10	et	et	NNP
cord-329515-ra20actc	175	11	al	al	NNP
cord-329515-ra20actc	175	12	.	.	NNP
cord-329515-ra20actc	175	13	,	,	,
cord-329515-ra20actc	175	14	1993a	1993a	CD
cord-329515-ra20actc	175	15	)	)	-RRB-
cord-329515-ra20actc	175	16	.	.	.
cord-329515-ra20actc	176	1	When	when	WRB
cord-329515-ra20actc	176	2	the	the	DT
cord-329515-ra20actc	176	3	mAb	mAb	NNP
cord-329515-ra20actc	176	4	G1/296	G1/296	NNP
cord-329515-ra20actc	176	5	was	be	VBD
cord-329515-ra20actc	176	6	tested	test	VBN
cord-329515-ra20actc	176	7	at	at	IN
cord-329515-ra20actc	176	8	a	a	DT
cord-329515-ra20actc	176	9	dilution	dilution	NN
cord-329515-ra20actc	176	10	of	of	IN
cord-329515-ra20actc	176	11	1:2,000	1:2,000	CD
cord-329515-ra20actc	176	12	,	,	,
cord-329515-ra20actc	176	13	the	the	DT
cord-329515-ra20actc	176	14	p63	p63	NN
cord-329515-ra20actc	176	15	staining	staining	NN
cord-329515-ra20actc	176	16	pattern	pattern	NN
cord-329515-ra20actc	176	17	was	be	VBD
cord-329515-ra20actc	176	18	very	very	RB
cord-329515-ra20actc	176	19	faint	faint	JJ
cord-329515-ra20actc	177	1	(	(	-LRB-
cord-329515-ra20actc	177	2	Fig	Fig	NNP
cord-329515-ra20actc	177	3	.	.	.
cord-329515-ra20actc	177	4	1	1	CD
cord-329515-ra20actc	177	5	b	b	NN
cord-329515-ra20actc	177	6	)	)	-RRB-
cord-329515-ra20actc	177	7	.	.	.
cord-329515-ra20actc	178	1	Since	since	IN
cord-329515-ra20actc	178	2	this	this	DT
cord-329515-ra20actc	178	3	dilution	dilution	NN
cord-329515-ra20actc	178	4	of	of	IN
cord-329515-ra20actc	178	5	antibody	antibody	NN
cord-329515-ra20actc	178	6	gave	give	VBD
cord-329515-ra20actc	178	7	a	a	DT
cord-329515-ra20actc	178	8	strong	strong	JJ
cord-329515-ra20actc	178	9	signal	signal	NN
cord-329515-ra20actc	178	10	with	with	IN
cord-329515-ra20actc	178	11	p63	p63	CD
cord-329515-ra20actc	178	12	transfected	transfecte	VBN
cord-329515-ra20actc	178	13	COS	COS	NNP
cord-329515-ra20actc	178	14	cells	cell	NNS
cord-329515-ra20actc	178	15	(	(	-LRB-
cord-329515-ra20actc	178	16	Fig	Fig	NNP
cord-329515-ra20actc	178	17	.	.	NNP
cord-329515-ra20actc	178	18	2	2	CD
cord-329515-ra20actc	178	19	a	a	LS
cord-329515-ra20actc	178	20	)	)	-RRB-
cord-329515-ra20actc	178	21	,	,	,
cord-329515-ra20actc	178	22	it	-PRON-	PRP
cord-329515-ra20actc	178	23	was	be	VBD
cord-329515-ra20actc	178	24	possible	possible	JJ
cord-329515-ra20actc	178	25	to	to	TO
cord-329515-ra20actc	178	26	readily	readily	RB
cord-329515-ra20actc	178	27	distinguish	distinguish	VB
cord-329515-ra20actc	178	28	between	between	IN
cord-329515-ra20actc	178	29	endogenous	endogenous	JJ
cord-329515-ra20actc	178	30	and	and	CC
cord-329515-ra20actc	178	31	transfected	transfecte	VBN
cord-329515-ra20actc	178	32	p63	p63	CD
cord-329515-ra20actc	178	33	.	.	.
cord-329515-ra20actc	179	1	COS	COS	NNP
cord-329515-ra20actc	179	2	cells	cell	NNS
cord-329515-ra20actc	179	3	transfectext	transfectext	XX
cord-329515-ra20actc	179	4	with	with	IN
cord-329515-ra20actc	179	5	IRi3wt	IRi3wt	NNP
cord-329515-ra20actc	179	6	exhibited	exhibit	VBD
cord-329515-ra20actc	179	7	the	the	DT
cord-329515-ra20actc	179	8	typical	typical	JJ
cord-329515-ra20actc	179	9	extended	extended	JJ
cord-329515-ra20actc	179	10	membrane	membrane	NN
cord-329515-ra20actc	179	11	structure	structure	NN
cord-329515-ra20actc	179	12	observed	observe	VBD
cord-329515-ra20actc	179	13	when	when	WRB
cord-329515-ra20actc	179	14	endogenous	endogenous	JJ
cord-329515-ra20actc	179	15	p63	p63	NN
cord-329515-ra20actc	179	16	was	be	VBD
cord-329515-ra20actc	179	17	stained	stain	VBN
cord-329515-ra20actc	179	18	(	(	-LRB-
cord-329515-ra20actc	179	19	Fig	fig	NN
cord-329515-ra20actc	179	20	.	.	.
cord-329515-ra20actc	179	21	  	  	_SP
cord-329515-ra20actc	179	22	2	2	CD
cord-329515-ra20actc	179	23	a	a	DT
cord-329515-ra20actc	179	24	,	,	,
cord-329515-ra20actc	179	25	left	left	JJ
cord-329515-ra20actc	179	26	cell	cell	NN
cord-329515-ra20actc	179	27	)	)	-RRB-
cord-329515-ra20actc	179	28	.	.	.
cord-329515-ra20actc	180	1	In	in	IN
cord-329515-ra20actc	180	2	addition	addition	NN
cord-329515-ra20actc	180	3	,	,	,
cord-329515-ra20actc	180	4	some	some	DT
cord-329515-ra20actc	180	5	of	of	IN
cord-329515-ra20actc	180	6	the	the	DT
cord-329515-ra20actc	180	7	cells	cell	NNS
cord-329515-ra20actc	180	8	showed	show	VBD
cord-329515-ra20actc	180	9	a	a	DT
cord-329515-ra20actc	180	10	large	large	JJ
cord-329515-ra20actc	180	11	tubular	tubular	JJ
cord-329515-ra20actc	180	12	network	network	NN
cord-329515-ra20actc	180	13	pattern	pattern	NN
cord-329515-ra20actc	180	14	that	that	WDT
cord-329515-ra20actc	180	15	was	be	VBD
cord-329515-ra20actc	180	16	not	not	RB
cord-329515-ra20actc	180	17	observed	observe	VBN
cord-329515-ra20actc	180	18	in	in	IN
cord-329515-ra20actc	180	19	the	the	DT
cord-329515-ra20actc	180	20	untransfected	untransfected	JJ
cord-329515-ra20actc	180	21	COS	COS	NNP
cord-329515-ra20actc	180	22	cells	cell	NNS
cord-329515-ra20actc	180	23	(	(	-LRB-
cord-329515-ra20actc	180	24	Fig	fig	NN
cord-329515-ra20actc	180	25	.	.	.
cord-329515-ra20actc	181	1	2	2	LS
cord-329515-ra20actc	181	2	a	a	DT
cord-329515-ra20actc	181	3	,	,	,
cord-329515-ra20actc	181	4	right	right	JJ
cord-329515-ra20actc	181	5	cell	cell	NN
cord-329515-ra20actc	181	6	)	)	-RRB-
cord-329515-ra20actc	182	1	(	(	-LRB-
cord-329515-ra20actc	182	2	Schweizer	Schweizer	NNP
cord-329515-ra20actc	182	3	et	et	NNP
cord-329515-ra20actc	182	4	al	al	NNP
cord-329515-ra20actc	182	5	.	.	NNP
cord-329515-ra20actc	182	6	,	,	,
cord-329515-ra20actc	182	7	1993b	1993b	CD
cord-329515-ra20actc	182	8	)	)	-RRB-
cord-329515-ra20actc	182	9	.	.	.
cord-329515-ra20actc	183	1	P63wt	P63wt	NNP
cord-329515-ra20actc	183	2	was	be	VBD
cord-329515-ra20actc	183	3	never	never	RB
cord-329515-ra20actc	183	4	detected	detect	VBN
cord-329515-ra20actc	183	5	at	at	IN
cord-329515-ra20actc	183	6	the	the	DT
cord-329515-ra20actc	183	7	cell	cell	NN
cord-329515-ra20actc	183	8	surface	surface	NN
cord-329515-ra20actc	183	9	,	,	,
cord-329515-ra20actc	183	10	even	even	RB
cord-329515-ra20actc	183	11	when	when	WRB
cord-329515-ra20actc	183	12	the	the	DT
cord-329515-ra20actc	183	13	expression	expression	NN
cord-329515-ra20actc	183	14	level	level	NN
cord-329515-ra20actc	183	15	was	be	VBD
cord-329515-ra20actc	183	16	very	very	RB
cord-329515-ra20actc	183	17	high	high	JJ
cord-329515-ra20actc	184	1	(	(	-LRB-
cord-329515-ra20actc	184	2	Fig	Fig	NNP
cord-329515-ra20actc	184	3	.	.	NNP
cord-329515-ra20actc	184	4	2	2	CD
cord-329515-ra20actc	184	5	b	b	NN
cord-329515-ra20actc	184	6	)	)	-RRB-
cord-329515-ra20actc	184	7	.	.	.
cord-329515-ra20actc	185	1	In	in	IN
cord-329515-ra20actc	185	2	our	-PRON-	PRP$
cord-329515-ra20actc	185	3	attempt	attempt	NN
cord-329515-ra20actc	185	4	to	to	TO
cord-329515-ra20actc	185	5	determine	determine	VB
cord-329515-ra20actc	185	6	the	the	DT
cord-329515-ra20actc	185	7	features	feature	NNS
cord-329515-ra20actc	185	8	of	of	IN
cord-329515-ra20actc	185	9	p63	p63	NN
cord-329515-ra20actc	185	10	responsible	responsible	JJ
cord-329515-ra20actc	185	11	for	for	IN
cord-329515-ra20actc	185	12	retention	retention	NN
cord-329515-ra20actc	185	13	we	-PRON-	PRP
cord-329515-ra20actc	185	14	initially	initially	RB
cord-329515-ra20actc	185	15	concentrated	concentrate	VBD
cord-329515-ra20actc	185	16	on	on	IN
cord-329515-ra20actc	185	17	the	the	DT
cord-329515-ra20actc	185	18	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	185	19	domain	domain	NN
cord-329515-ra20actc	185	20	of	of	IN
cord-329515-ra20actc	185	21	the	the	DT
cord-329515-ra20actc	185	22	protein	protein	NN
cord-329515-ra20actc	185	23	.	.	.
cord-329515-ra20actc	186	1	The	the	DT
cord-329515-ra20actc	186	2	first	first	JJ
cord-329515-ra20actc	186	3	construct	construct	NN
cord-329515-ra20actc	186	4	to	to	TO
cord-329515-ra20actc	186	5	be	be	VB
cord-329515-ra20actc	186	6	prepared	prepare	VBN
cord-329515-ra20actc	186	7	was	be	VBD
cord-329515-ra20actc	186	8	a	a	DT
cord-329515-ra20actc	186	9	truncated	truncated	JJ
cord-329515-ra20actc	186	10	form	form	NN
cord-329515-ra20actc	186	11	of	of	IN
cord-329515-ra20actc	186	12	p63	p63	NN
cord-329515-ra20actc	186	13	in	in	IN
cord-329515-ra20actc	186	14	which	which	WDT
cord-329515-ra20actc	186	15	the	the	DT
cord-329515-ra20actc	186	16	amino	amino	NN
cord-329515-ra20actc	186	17	-	-	HYPH
cord-329515-ra20actc	186	18	terminal	terminal	NN
cord-329515-ra20actc	186	19	residues	residue	NNS
cord-329515-ra20actc	186	20	2	2	CD
cord-329515-ra20actc	186	21	-	-	SYM
cord-329515-ra20actc	186	22	101	101	CD
cord-329515-ra20actc	186	23	of	of	IN
cord-329515-ra20actc	186	24	the	the	DT
cord-329515-ra20actc	186	25	106-amino	106-amino	CD
cord-329515-ra20actc	186	26	acid	acid	NN
cord-329515-ra20actc	186	27	-	-	HYPH
cord-329515-ra20actc	186	28	long	long	JJ
cord-329515-ra20actc	186	29	p63	p63	CD
cord-329515-ra20actc	186	30	tail	tail	NN
cord-329515-ra20actc	186	31	were	be	VBD
cord-329515-ra20actc	186	32	deleted	delete	VBN
cord-329515-ra20actc	186	33	(	(	-LRB-
cord-329515-ra20actc	186	34	A2	A2	NNP
cord-329515-ra20actc	186	35	-	-	HYPH
cord-329515-ra20actc	186	36	101	101	CD
cord-329515-ra20actc	186	37	,	,	,
cord-329515-ra20actc	186	38	Fig	Fig	NNP
cord-329515-ra20actc	186	39	.	.	NNP
cord-329515-ra20actc	186	40	3	3	CD
cord-329515-ra20actc	186	41	)	)	-RRB-
cord-329515-ra20actc	186	42	.	.	.
cord-329515-ra20actc	187	1	Since	since	IN
cord-329515-ra20actc	187	2	p63	p63	NNP
cord-329515-ra20actc	187	3	has	have	VBZ
cord-329515-ra20actc	187	4	a	a	DT
cord-329515-ra20actc	187	5	type	type	NN
cord-329515-ra20actc	187	6	II	II	NNP
cord-329515-ra20actc	187	7	membrane	membrane	NN
cord-329515-ra20actc	187	8	orientation	orientation	NN
cord-329515-ra20actc	187	9	,	,	,
cord-329515-ra20actc	187	10	the	the	DT
cord-329515-ra20actc	187	11	first	first	JJ
cord-329515-ra20actc	187	12	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	187	13	amino	amino	NN
cord-329515-ra20actc	187	14	acid	acid	NN
cord-329515-ra20actc	187	15	representing	represent	VBG
cord-329515-ra20actc	187	16	the	the	DT
cord-329515-ra20actc	187	17	initiator	initiator	NN
cord-329515-ra20actc	187	18	methionine	methionine	NN
cord-329515-ra20actc	187	19	could	could	MD
cord-329515-ra20actc	187	20	not	not	RB
cord-329515-ra20actc	187	21	be	be	VB
cord-329515-ra20actc	187	22	removed	remove	VBN
cord-329515-ra20actc	187	23	.	.	.
cord-329515-ra20actc	188	1	When	when	WRB
cord-329515-ra20actc	188	2	A2	A2	NNP
cord-329515-ra20actc	188	3	-	-	HYPH
cord-329515-ra20actc	188	4	101	101	NNP
cord-329515-ra20actc	188	5	was	be	VBD
cord-329515-ra20actc	188	6	expressed	express	VBN
cord-329515-ra20actc	188	7	in	in	IN
cord-329515-ra20actc	188	8	COS	COS	NNP
cord-329515-ra20actc	188	9	cells	cell	NNS
cord-329515-ra20actc	188	10	,	,	,
cord-329515-ra20actc	188	11	it	-PRON-	PRP
cord-329515-ra20actc	188	12	was	be	VBD
cord-329515-ra20actc	188	13	clearly	clearly	RB
cord-329515-ra20actc	188	14	present	present	JJ
cord-329515-ra20actc	188	15	on	on	IN
cord-329515-ra20actc	188	16	the	the	DT
cord-329515-ra20actc	188	17	plasma	plasma	NN
cord-329515-ra20actc	188	18	membrane	membrane	NN
cord-329515-ra20actc	188	19	in	in	IN
cord-329515-ra20actc	188	20	about	about	IN
cord-329515-ra20actc	188	21	half	half	NN
cord-329515-ra20actc	188	22	of	of	IN
cord-329515-ra20actc	188	23	the	the	DT
cord-329515-ra20actc	188	24	transfected	transfecte	VBN
cord-329515-ra20actc	188	25	cells	cell	NNS
cord-329515-ra20actc	188	26	(	(	-LRB-
cord-329515-ra20actc	188	27	Fig	fig	NN
cord-329515-ra20actc	188	28	.	.	.
cord-329515-ra20actc	188	29	 	 	_SP
cord-329515-ra20actc	189	1	2	2	LS
cord-329515-ra20actc	189	2	d	d	NN
cord-329515-ra20actc	189	3	)	)	-RRB-
cord-329515-ra20actc	189	4	.	.	.
cord-329515-ra20actc	190	1	Upon	upon	IN
cord-329515-ra20actc	190	2	permeabilization	permeabilization	NN
cord-329515-ra20actc	190	3	,	,	,
cord-329515-ra20actc	190	4	A2	A2	NNP
cord-329515-ra20actc	190	5	-	-	HYPH
cord-329515-ra20actc	190	6	101	101	NNP
cord-329515-ra20actc	190	7	was	be	VBD
cord-329515-ra20actc	190	8	detected	detect	VBN
cord-329515-ra20actc	190	9	primarily	primarily	RB
cord-329515-ra20actc	190	10	in	in	IN
cord-329515-ra20actc	190	11	the	the	DT
cord-329515-ra20actc	190	12	rough	rough	JJ
cord-329515-ra20actc	190	13	ER	er	NN
cord-329515-ra20actc	190	14	as	as	IN
cord-329515-ra20actc	190	15	indicated	indicate	VBN
cord-329515-ra20actc	190	16	by	by	IN
cord-329515-ra20actc	190	17	the	the	DT
cord-329515-ra20actc	190	18	reticular	reticular	JJ
cord-329515-ra20actc	190	19	staining	staining	NN
cord-329515-ra20actc	190	20	pattern	pattern	NN
cord-329515-ra20actc	190	21	along	along	IN
cord-329515-ra20actc	190	22	with	with	IN
cord-329515-ra20actc	190	23	labeling	labeling	NN
cord-329515-ra20actc	190	24	of	of	IN
cord-329515-ra20actc	190	25	the	the	DT
cord-329515-ra20actc	190	26	outer	outer	JJ
cord-329515-ra20actc	190	27	nuclear	nuclear	JJ
cord-329515-ra20actc	190	28	membrane	membrane	NN
cord-329515-ra20actc	190	29	(	(	-LRB-
cord-329515-ra20actc	190	30	Fig	Fig	NNP
cord-329515-ra20actc	190	31	.	.	.
cord-329515-ra20actc	190	32	2	2	CD
cord-329515-ra20actc	190	33	 	 	_SP
cord-329515-ra20actc	190	34	c	c	NN
cord-329515-ra20actc	190	35	)	)	-RRB-
cord-329515-ra20actc	190	36	.	.	.
cord-329515-ra20actc	191	1	Occasionally	occasionally	RB
cord-329515-ra20actc	191	2	it	-PRON-	PRP
cord-329515-ra20actc	191	3	was	be	VBD
cord-329515-ra20actc	191	4	found	find	VBN
cord-329515-ra20actc	191	5	in	in	IN
cord-329515-ra20actc	191	6	the	the	DT
cord-329515-ra20actc	191	7	Golgi	Golgi	NNP
cord-329515-ra20actc	191	8	region	region	NN
cord-329515-ra20actc	191	9	or	or	CC
cord-329515-ra20actc	191	10	at	at	IN
cord-329515-ra20actc	191	11	the	the	DT
cord-329515-ra20actc	191	12	cell	cell	NN
cord-329515-ra20actc	191	13	surface	surface	NN
cord-329515-ra20actc	191	14	(	(	-LRB-
cord-329515-ra20actc	191	15	see	see	VB
cord-329515-ra20actc	191	16	insert	insert	NN
cord-329515-ra20actc	191	17	of	of	IN
cord-329515-ra20actc	191	18	Fig	Fig	NNP
cord-329515-ra20actc	191	19	.	.	.
cord-329515-ra20actc	192	1	2	2	LS
cord-329515-ra20actc	192	2	c	c	NN
cord-329515-ra20actc	192	3	for	for	IN
cord-329515-ra20actc	192	4	an	an	DT
cord-329515-ra20actc	192	5	example	example	NN
cord-329515-ra20actc	192	6	of	of	IN
cord-329515-ra20actc	192	7	surface	surface	NN
cord-329515-ra20actc	192	8	staining	staining	NN
cord-329515-ra20actc	192	9	)	)	-RRB-
cord-329515-ra20actc	192	10	.	.	.
cord-329515-ra20actc	193	1	In	in	IN
cord-329515-ra20actc	193	2	the	the	DT
cord-329515-ra20actc	193	3	construction	construction	NN
cord-329515-ra20actc	193	4	of	of	IN
cord-329515-ra20actc	193	5	A2	A2	NNP
cord-329515-ra20actc	193	6	-	-	HYPH
cord-329515-ra20actc	193	7	101	101	CD
cord-329515-ra20actc	193	8	,	,	,
cord-329515-ra20actc	193	9	two	two	CD
cord-329515-ra20actc	193	10	arginine	arginine	NN
cord-329515-ra20actc	193	11	residues	residue	NNS
cord-329515-ra20actc	193	12	became	become	VBD
cord-329515-ra20actc	193	13	positioned	position	VBN
cord-329515-ra20actc	193	14	near	near	IN
cord-329515-ra20actc	193	15	the	the	DT
cord-329515-ra20actc	193	16	extreme	extreme	JJ
cord-329515-ra20actc	193	17	NI	NI	NNP
cord-329515-ra20actc	193	18	-	-	HYPH
cord-329515-ra20actc	193	19	I2-terminus	I2-terminus	NNP
cord-329515-ra20actc	193	20	due	due	IN
cord-329515-ra20actc	193	21	to	to	IN
cord-329515-ra20actc	193	22	the	the	DT
cord-329515-ra20actc	193	23	deletion	deletion	NN
cord-329515-ra20actc	193	24	of	of	IN
cord-329515-ra20actc	193	25	100	100	CD
cord-329515-ra20actc	193	26	amino	amino	NN
cord-329515-ra20actc	193	27	acids	acid	NNS
cord-329515-ra20actc	193	28	within	within	IN
cord-329515-ra20actc	193	29	the	the	DT
cord-329515-ra20actc	193	30	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	193	31	tail	tail	NN
cord-329515-ra20actc	193	32	(	(	-LRB-
cord-329515-ra20actc	193	33	Fig	fig	NN
cord-329515-ra20actc	193	34	.	.	.
cord-329515-ra20actc	193	35	3	3	CD
cord-329515-ra20actc	193	36	)	)	-RRB-
cord-329515-ra20actc	193	37	.	.	.
cord-329515-ra20actc	194	1	We	-PRON-	PRP
cord-329515-ra20actc	194	2	therefore	therefore	RB
cord-329515-ra20actc	194	3	considered	consider	VBD
cord-329515-ra20actc	194	4	the	the	DT
cord-329515-ra20actc	194	5	possibility	possibility	NN
cord-329515-ra20actc	194	6	that	that	IN
cord-329515-ra20actc	194	7	these	these	DT
cord-329515-ra20actc	194	8	positively	positively	RB
cord-329515-ra20actc	194	9	charged	charge	VBN
cord-329515-ra20actc	194	10	amino	amino	NN
cord-329515-ra20actc	194	11	acids	acid	NNS
cord-329515-ra20actc	194	12	might	may	MD
cord-329515-ra20actc	194	13	serve	serve	VB
cord-329515-ra20actc	194	14	as	as	IN
cord-329515-ra20actc	194	15	an	an	DT
cord-329515-ra20actc	194	16	ERtargeting	ertargete	VBG
cord-329515-ra20actc	194	17	signal	signal	NN
cord-329515-ra20actc	194	18	,	,	,
cord-329515-ra20actc	194	19	thereby	thereby	RB
cord-329515-ra20actc	194	20	impairing	impair	VBG
cord-329515-ra20actc	194	21	the	the	DT
cord-329515-ra20actc	194	22	normal	normal	JJ
cord-329515-ra20actc	194	23	transport	transport	NN
cord-329515-ra20actc	194	24	of	of	IN
cord-329515-ra20actc	194	25	the	the	DT
cord-329515-ra20actc	194	26	protein	protein	NN
cord-329515-ra20actc	194	27	(	(	-LRB-
cord-329515-ra20actc	194	28	Jackson	Jackson	NNP
cord-329515-ra20actc	194	29	et	et	NNP
cord-329515-ra20actc	194	30	al	al	NNP
cord-329515-ra20actc	194	31	.	.	NNP
cord-329515-ra20actc	194	32	,	,	,
cord-329515-ra20actc	194	33	1990	1990	CD
cord-329515-ra20actc	194	34	)	)	-RRB-
cord-329515-ra20actc	194	35	.	.	.
cord-329515-ra20actc	195	1	These	these	DT
cord-329515-ra20actc	195	2	arginine	arginine	NN
cord-329515-ra20actc	195	3	residues	residue	NNS
cord-329515-ra20actc	195	4	(	(	-LRB-
cord-329515-ra20actc	195	5	located	locate	VBN
cord-329515-ra20actc	195	6	in	in	IN
cord-329515-ra20actc	195	7	position	position	NN
cord-329515-ra20actc	195	8	-2	-2	NN
cord-329515-ra20actc	195	9	and	and	CC
cord-329515-ra20actc	195	10	-3	-3	NNP
cord-329515-ra20actc	196	1	from	from	IN
cord-329515-ra20actc	196	2	the	the	DT
cord-329515-ra20actc	196	3	NH2	NH2	NNP
cord-329515-ra20actc	196	4	terminus	terminus	NN
cord-329515-ra20actc	196	5	of	of	IN
cord-329515-ra20actc	196	6	A2	A2	NNP
cord-329515-ra20actc	196	7	-	-	HYPH
cord-329515-ra20actc	196	8	101	101	CD
cord-329515-ra20actc	196	9	)	)	-RRB-
cord-329515-ra20actc	196	10	were	be	VBD
cord-329515-ra20actc	196	11	therefore	therefore	RB
cord-329515-ra20actc	196	12	changed	change	VBN
cord-329515-ra20actc	196	13	to	to	IN
cord-329515-ra20actc	196	14	alanines	alanines	NNP
cord-329515-ra20actc	196	15	(	(	-LRB-
cord-329515-ra20actc	196	16	A2	A2	NNP
cord-329515-ra20actc	196	17	-	-	HYPH
cord-329515-ra20actc	196	18	101AA	101AA	NNP
cord-329515-ra20actc	196	19	,	,	,
cord-329515-ra20actc	196	20	Fig	Fig	NNP
cord-329515-ra20actc	196	21	.	.	.
cord-329515-ra20actc	196	22	 	 	_SP
cord-329515-ra20actc	197	1	3	3	LS
cord-329515-ra20actc	197	2	)	)	-RRB-
cord-329515-ra20actc	198	1	and	and	CC
cord-329515-ra20actc	198	2	the	the	DT
cord-329515-ra20actc	198	3	effect	effect	NN
cord-329515-ra20actc	198	4	monitored	monitor	VBN
cord-329515-ra20actc	198	5	by	by	IN
cord-329515-ra20actc	198	6	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	198	7	as	as	IN
cord-329515-ra20actc	198	8	outlined	outline	VBN
cord-329515-ra20actc	198	9	above	above	RB
cord-329515-ra20actc	198	10	.	.	.
cord-329515-ra20actc	199	1	A2	A2	NNP
cord-329515-ra20actc	199	2	-	-	HYPH
cord-329515-ra20actc	199	3	101AA	101AA	NNP
cord-329515-ra20actc	199	4	showed	show	VBD
cord-329515-ra20actc	199	5	strong	strong	JJ
cord-329515-ra20actc	199	6	cell	cell	NN
cord-329515-ra20actc	199	7	surface	surface	NN
cord-329515-ra20actc	199	8	expression	expression	NN
cord-329515-ra20actc	199	9	over	over	IN
cord-329515-ra20actc	199	10	the	the	DT
cord-329515-ra20actc	199	11	entire	entire	JJ
cord-329515-ra20actc	199	12	transfected	transfected	JJ
cord-329515-ra20actc	199	13	cell	cell	NN
cord-329515-ra20actc	199	14	population	population	NN
cord-329515-ra20actc	199	15	(	(	-LRB-
cord-329515-ra20actc	199	16	Fig	Fig	NNP
cord-329515-ra20actc	199	17	.	.	.
cord-329515-ra20actc	199	18	2	2	CD
cord-329515-ra20actc	199	19	f	f	NNP
cord-329515-ra20actc	199	20	)	)	-RRB-
cord-329515-ra20actc	199	21	.	.	.
cord-329515-ra20actc	200	1	Further	further	RB
cord-329515-ra20actc	200	2	,	,	,
cord-329515-ra20actc	200	3	the	the	DT
cord-329515-ra20actc	200	4	staining	staining	NN
cord-329515-ra20actc	200	5	pattern	pattern	NN
cord-329515-ra20actc	200	6	observed	observe	VBN
cord-329515-ra20actc	200	7	in	in	IN
cord-329515-ra20actc	200	8	permeabilized	permeabilized	JJ
cord-329515-ra20actc	200	9	cells	cell	NNS
cord-329515-ra20actc	200	10	(	(	-LRB-
cord-329515-ra20actc	200	11	Fig	Fig	NNP
cord-329515-ra20actc	200	12	.	.	NNP
cord-329515-ra20actc	200	13	2	2	CD
cord-329515-ra20actc	200	14	e	e	NN
cord-329515-ra20actc	200	15	)	)	-RRB-
cord-329515-ra20actc	200	16	was	be	VBD
cord-329515-ra20actc	200	17	typical	typical	JJ
cord-329515-ra20actc	200	18	for	for	IN
cord-329515-ra20actc	200	19	a	a	DT
cord-329515-ra20actc	200	20	cell	cell	NN
cord-329515-ra20actc	200	21	surface	surface	NN
cord-329515-ra20actc	200	22	protein	protein	NN
cord-329515-ra20actc	200	23	including	include	VBG
cord-329515-ra20actc	200	24	juxtanuclear	juxtanuclear	NNP
cord-329515-ra20actc	200	25	Golgi	Golgi	NNP
cord-329515-ra20actc	200	26	and	and	CC
cord-329515-ra20actc	200	27	plasma	plasma	NN
cord-329515-ra20actc	200	28	membrane	membrane	NN
cord-329515-ra20actc	200	29	staining	staining	NN
cord-329515-ra20actc	200	30	.	.	.
cord-329515-ra20actc	201	1	Taken	take	VBN
cord-329515-ra20actc	201	2	together	together	RB
cord-329515-ra20actc	201	3	,	,	,
cord-329515-ra20actc	201	4	these	these	DT
cord-329515-ra20actc	201	5	data	datum	NNS
cord-329515-ra20actc	201	6	demonstrated	demonstrate	VBD
cord-329515-ra20actc	201	7	that	that	IN
cord-329515-ra20actc	201	8	the	the	DT
cord-329515-ra20actc	201	9	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	201	10	domain	domain	NN
cord-329515-ra20actc	201	11	of	of	IN
cord-329515-ra20actc	201	12	p63	p63	CD
cord-329515-ra20actc	201	13	is	be	VBZ
cord-329515-ra20actc	201	14	necessary	necessary	JJ
cord-329515-ra20actc	201	15	for	for	IN
cord-329515-ra20actc	201	16	correct	correct	JJ
cord-329515-ra20actc	201	17	intracellular	intracellular	JJ
cord-329515-ra20actc	201	18	localization	localization	NN
cord-329515-ra20actc	201	19	.	.	.
cord-329515-ra20actc	202	1	To	to	TO
cord-329515-ra20actc	202	2	define	define	VB
cord-329515-ra20actc	202	3	more	more	RBR
cord-329515-ra20actc	202	4	precisely	precisely	RB
cord-329515-ra20actc	202	5	the	the	DT
cord-329515-ra20actc	202	6	location	location	NN
cord-329515-ra20actc	202	7	of	of	IN
cord-329515-ra20actc	202	8	the	the	DT
cord-329515-ra20actc	202	9	retention	retention	NN
cord-329515-ra20actc	202	10	information	information	NN
cord-329515-ra20actc	202	11	in	in	IN
cord-329515-ra20actc	202	12	the	the	DT
cord-329515-ra20actc	202	13	p63	p63	CD
cord-329515-ra20actc	202	14	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	202	15	tail	tail	NN
cord-329515-ra20actc	202	16	we	-PRON-	PRP
cord-329515-ra20actc	202	17	made	make	VBD
cord-329515-ra20actc	202	18	a	a	DT
cord-329515-ra20actc	202	19	construct	construct	NN
cord-329515-ra20actc	202	20	(	(	-LRB-
cord-329515-ra20actc	202	21	A16	A16	NNP
cord-329515-ra20actc	202	22	-	-	SYM
cord-329515-ra20actc	202	23	101	101	CD
cord-329515-ra20actc	202	24	,	,	,
cord-329515-ra20actc	202	25	Fig	Fig	NNP
cord-329515-ra20actc	202	26	.	.	NNP
cord-329515-ra20actc	202	27	3	3	CD
cord-329515-ra20actc	202	28	)	)	-RRB-
cord-329515-ra20actc	202	29	in	in	IN
cord-329515-ra20actc	202	30	which	which	WDT
cord-329515-ra20actc	202	31	amino	amino	JJ
cord-329515-ra20actc	202	32	acids	acid	NNS
cord-329515-ra20actc	202	33	2	2	CD
cord-329515-ra20actc	202	34	-	-	SYM
cord-329515-ra20actc	202	35	15	15	CD
cord-329515-ra20actc	202	36	of	of	IN
cord-329515-ra20actc	202	37	p63wt	p63wt	NNP
cord-329515-ra20actc	202	38	were	be	VBD
cord-329515-ra20actc	202	39	added	add	VBN
cord-329515-ra20actc	202	40	back	back	RB
cord-329515-ra20actc	202	41	to	to	IN
cord-329515-ra20actc	202	42	the	the	DT
cord-329515-ra20actc	202	43	A2	A2	NNP
cord-329515-ra20actc	202	44	-	-	HYPH
cord-329515-ra20actc	202	45	101	101	CD
cord-329515-ra20actc	202	46	deletion	deletion	NN
cord-329515-ra20actc	202	47	mutant	mutant	NN
cord-329515-ra20actc	202	48	.	.	.
cord-329515-ra20actc	203	1	When	when	WRB
cord-329515-ra20actc	203	2	cells	cell	NNS
cord-329515-ra20actc	203	3	expressing	express	VBG
cord-329515-ra20actc	203	4	this	this	DT
cord-329515-ra20actc	203	5	construct	construct	NN
cord-329515-ra20actc	203	6	were	be	VBD
cord-329515-ra20actc	203	7	analyzed	analyze	VBN
cord-329515-ra20actc	203	8	by	by	IN
cord-329515-ra20actc	203	9	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	203	10	,	,	,
cord-329515-ra20actc	203	11	an	an	DT
cord-329515-ra20actc	203	12	internal	internal	JJ
cord-329515-ra20actc	203	13	staining	staining	NN
cord-329515-ra20actc	203	14	pattern	pattern	NN
cord-329515-ra20actc	203	15	close	close	RB
cord-329515-ra20actc	203	16	to	to	IN
cord-329515-ra20actc	203	17	that	that	DT
cord-329515-ra20actc	203	18	of	of	IN
cord-329515-ra20actc	203	19	p63wt	p63wt	NNP
cord-329515-ra20actc	203	20	was	be	VBD
cord-329515-ra20actc	203	21	observed	observe	VBN
cord-329515-ra20actc	203	22	except	except	IN
cord-329515-ra20actc	203	23	that	that	IN
cord-329515-ra20actc	203	24	no	no	DT
cord-329515-ra20actc	203	25	cells	cell	NNS
cord-329515-ra20actc	203	26	with	with	IN
cord-329515-ra20actc	203	27	the	the	DT
cord-329515-ra20actc	203	28	tubular	tubular	JJ
cord-329515-ra20actc	203	29	network	network	NN
cord-329515-ra20actc	203	30	type	type	NN
cord-329515-ra20actc	203	31	pattern	pattern	NN
cord-329515-ra20actc	203	32	were	be	VBD
cord-329515-ra20actc	203	33	found	find	VBN
cord-329515-ra20actc	203	34	(	(	-LRB-
cord-329515-ra20actc	203	35	Fig	fig	NN
cord-329515-ra20actc	203	36	.	.	.
cord-329515-ra20actc	204	1	4	4	LS
cord-329515-ra20actc	204	2	a	a	LS
cord-329515-ra20actc	204	3	)	)	-RRB-
cord-329515-ra20actc	204	4	.	.	.
cord-329515-ra20actc	205	1	Labeling	labeling	NN
cord-329515-ra20actc	205	2	of	of	IN
cord-329515-ra20actc	205	3	nonpermeabilized	nonpermeabilized	JJ
cord-329515-ra20actc	205	4	COS	COS	NNP
cord-329515-ra20actc	205	5	cells	cell	NNS
cord-329515-ra20actc	205	6	with	with	IN
cord-329515-ra20actc	205	7	anti	anti	JJ
cord-329515-ra20actc	205	8	-	-	JJ
cord-329515-ra20actc	205	9	p63	p63	JJ
cord-329515-ra20actc	205	10	mAbs	mAbs	NNP
cord-329515-ra20actc	205	11	revealed	reveal	VBD
cord-329515-ra20actc	205	12	that	that	IN
cord-329515-ra20actc	205	13	A16	A16	NNP
cord-329515-ra20actc	205	14	-	-	HYPH
cord-329515-ra20actc	205	15	101	101	NNP
cord-329515-ra20actc	205	16	is	be	VBZ
cord-329515-ra20actc	205	17	predomi-	predomi-	NN
cord-329515-ra20actc	206	1	For	for	IN
cord-329515-ra20actc	206	2	detection	detection	NN
cord-329515-ra20actc	206	3	an	an	DT
cord-329515-ra20actc	206	4	mAb	mAb	NNP
cord-329515-ra20actc	206	5	to	to	IN
cord-329515-ra20actc	206	6	p63	p63	CD
cord-329515-ra20actc	206	7	followed	follow	VBN
cord-329515-ra20actc	206	8	by	by	IN
cord-329515-ra20actc	206	9	goat	goat	NN
cord-329515-ra20actc	206	10	anti	anti	JJ
cord-329515-ra20actc	206	11	-	-	JJ
cord-329515-ra20actc	206	12	mouse	mouse	JJ
cord-329515-ra20actc	206	13	FITC	FITC	NNP
cord-329515-ra20actc	206	14	was	be	VBD
cord-329515-ra20actc	206	15	used	use	VBN
cord-329515-ra20actc	206	16	.	.	.
cord-329515-ra20actc	207	1	In	in	IN
cord-329515-ra20actc	207	2	contrast	contrast	NN
cord-329515-ra20actc	207	3	to	to	IN
cord-329515-ra20actc	207	4	p63wt	p63wt	NNP
cord-329515-ra20actc	207	5	,	,	,
cord-329515-ra20actc	207	6	constructs	construct	VBZ
cord-329515-ra20actc	207	7	A2	A2	NNP
cord-329515-ra20actc	207	8	-	-	HYPH
cord-329515-ra20actc	207	9	101	101	NNP
cord-329515-ra20actc	207	10	and	and	CC
cord-329515-ra20actc	207	11	A2	A2	NNP
cord-329515-ra20actc	207	12	-	-	HYPH
cord-329515-ra20actc	207	13	101AA	101AA	NNP
cord-329515-ra20actc	207	14	were	be	VBD
cord-329515-ra20actc	207	15	observed	observe	VBN
cord-329515-ra20actc	207	16	at	at	IN
cord-329515-ra20actc	207	17	the	the	DT
cord-329515-ra20actc	207	18	plasma	plasma	NN
cord-329515-ra20actc	207	19	membrane	membrane	NN
cord-329515-ra20actc	207	20	.	.	.
cord-329515-ra20actc	208	1	Bar	bar	NN
cord-329515-ra20actc	208	2	,	,	,
cord-329515-ra20actc	208	3	(	(	-LRB-
cord-329515-ra20actc	208	4	a	a	NN
cord-329515-ra20actc	208	5	and	and	CC
cord-329515-ra20actc	208	6	b	b	LS
cord-329515-ra20actc	208	7	)	)	-RRB-
cord-329515-ra20actc	208	8	28/~m	28/~m	NNP
cord-329515-ra20actc	208	9	;	;	:
cord-329515-ra20actc	208	10	(	(	-LRB-
cord-329515-ra20actc	208	11	c	c	NN
cord-329515-ra20actc	208	12	-	-	HYPH
cord-329515-ra20actc	208	13	f	f	NNP
cord-329515-ra20actc	208	14	)	)	-RRB-
cord-329515-ra20actc	208	15	42/~m	42/~m	NNP
cord-329515-ra20actc	208	16	.	.	.
cord-329515-ra20actc	209	1	nantly	nantly	NNP
cord-329515-ra20actc	209	2	localized	localize	VBN
cord-329515-ra20actc	209	3	intracellularly	intracellularly	RB
cord-329515-ra20actc	209	4	(	(	-LRB-
cord-329515-ra20actc	209	5	Fig	Fig	NNP
cord-329515-ra20actc	209	6	.	.	.
cord-329515-ra20actc	209	7	4	4	CD
cord-329515-ra20actc	209	8	b	b	LS
cord-329515-ra20actc	209	9	)	)	-RRB-
cord-329515-ra20actc	210	1	;	;	:
cord-329515-ra20actc	210	2	an	an	DT
cord-329515-ra20actc	210	3	occasional	occasional	JJ
cord-329515-ra20actc	210	4	cell	cell	NN
cord-329515-ra20actc	210	5	showed	show	VBD
cord-329515-ra20actc	210	6	weak	weak	JJ
cord-329515-ra20actc	210	7	staining	staining	NN
cord-329515-ra20actc	210	8	of	of	IN
cord-329515-ra20actc	210	9	the	the	DT
cord-329515-ra20actc	210	10	plasma	plasma	NN
cord-329515-ra20actc	210	11	membrane	membrane	NN
cord-329515-ra20actc	210	12	(	(	-LRB-
cord-329515-ra20actc	210	13	Fig	Fig	NNP
cord-329515-ra20actc	210	14	.	.	.
cord-329515-ra20actc	210	15	4	4	CD
cord-329515-ra20actc	210	16	b	b	NN
cord-329515-ra20actc	210	17	,	,	,
cord-329515-ra20actc	210	18	inset	inset	NN
cord-329515-ra20actc	210	19	)	)	-RRB-
cord-329515-ra20actc	210	20	.	.	.
cord-329515-ra20actc	211	1	When	when	WRB
cord-329515-ra20actc	211	2	the	the	DT
cord-329515-ra20actc	211	3	NH~-terminal	NH~-terminal	NNP
cord-329515-ra20actc	211	4	portion	portion	NN
cord-329515-ra20actc	211	5	of	of	IN
cord-329515-ra20actc	211	6	p63	p63	CD
cord-329515-ra20actc	211	7	was	be	VBD
cord-329515-ra20actc	211	8	extended	extend	VBN
cord-329515-ra20actc	211	9	to	to	TO
cord-329515-ra20actc	211	10	include	include	VB
cord-329515-ra20actc	211	11	the	the	DT
cord-329515-ra20actc	211	12	23	23	CD
cord-329515-ra20actc	211	13	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	211	14	residues	residue	NNS
cord-329515-ra20actc	211	15	of	of	IN
cord-329515-ra20actc	211	16	the	the	DT
cord-329515-ra20actc	211	17	p63wt	p63wt	CD
cord-329515-ra20actc	211	18	sequence	sequence	NN
cord-329515-ra20actc	211	19	(	(	-LRB-
cord-329515-ra20actc	211	20	A24	A24	NNP
cord-329515-ra20actc	211	21	-	-	HYPH
cord-329515-ra20actc	211	22	101	101	CD
cord-329515-ra20actc	211	23	,	,	,
cord-329515-ra20actc	211	24	Fig	Fig	NNP
cord-329515-ra20actc	211	25	.	.	NNP
cord-329515-ra20actc	211	26	3	3	CD
cord-329515-ra20actc	211	27	)	)	-RRB-
cord-329515-ra20actc	211	28	,	,	,
cord-329515-ra20actc	211	29	the	the	DT
cord-329515-ra20actc	211	30	resultant	resultant	JJ
cord-329515-ra20actc	211	31	protein	protein	NN
cord-329515-ra20actc	211	32	behaved	behave	VBD
cord-329515-ra20actc	211	33	like	like	IN
cord-329515-ra20actc	211	34	p63wt	p63wt	NNP
cord-329515-ra20actc	211	35	when	when	WRB
cord-329515-ra20actc	211	36	analyzed	analyze	VBN
cord-329515-ra20actc	211	37	by	by	IN
cord-329515-ra20actc	211	38	indirect	indirect	JJ
cord-329515-ra20actc	211	39	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	211	40	after	after	IN
cord-329515-ra20actc	211	41	transfection	transfection	NN
cord-329515-ra20actc	211	42	(	(	-LRB-
cord-329515-ra20actc	211	43	Fig	Fig	NNP
cord-329515-ra20actc	211	44	.	.	NNP
cord-329515-ra20actc	211	45	4	4	CD
cord-329515-ra20actc	211	46	,	,	,
cord-329515-ra20actc	211	47	c	c	NN
cord-329515-ra20actc	211	48	and	and	CC
cord-329515-ra20actc	211	49	d	d	NNP
cord-329515-ra20actc	211	50	)	)	-RRB-
cord-329515-ra20actc	211	51	.	.	.
cord-329515-ra20actc	212	1	The	the	DT
cord-329515-ra20actc	212	2	mutant	mutant	JJ
cord-329515-ra20actc	212	3	protein	protein	NN
cord-329515-ra20actc	212	4	was	be	VBD
cord-329515-ra20actc	212	5	completely	completely	RB
cord-329515-ra20actc	212	6	retained	retain	VBN
cord-329515-ra20actc	212	7	inside	inside	IN
cord-329515-ra20actc	212	8	the	the	DT
cord-329515-ra20actc	212	9	cell	cell	NN
cord-329515-ra20actc	212	10	(	(	-LRB-
cord-329515-ra20actc	212	11	Fig	Fig	NNP
cord-329515-ra20actc	212	12	.	.	.
cord-329515-ra20actc	212	13	4	4	CD
cord-329515-ra20actc	212	14	d	d	CD
cord-329515-ra20actc	212	15	)	)	-RRB-
cord-329515-ra20actc	212	16	.	.	.
cord-329515-ra20actc	213	1	In	in	IN
cord-329515-ra20actc	213	2	addition	addition	NN
cord-329515-ra20actc	213	3	,	,	,
cord-329515-ra20actc	213	4	the	the	DT
cord-329515-ra20actc	213	5	A24	A24	NNP
cord-329515-ra20actc	213	6	-	-	HYPH
cord-329515-ra20actc	213	7	101	101	CD
cord-329515-ra20actc	213	8	staining	staining	NN
cord-329515-ra20actc	213	9	in	in	IN
cord-329515-ra20actc	213	10	permeabilized	permeabilized	JJ
cord-329515-ra20actc	213	11	ceils	ceil	NNS
cord-329515-ra20actc	213	12	was	be	VBD
cord-329515-ra20actc	213	13	indistinguishable	indistinguishable	JJ
cord-329515-ra20actc	213	14	from	from	IN
cord-329515-ra20actc	213	15	that	that	DT
cord-329515-ra20actc	213	16	ofp63wt	ofp63wt	XX
cord-329515-ra20actc	214	1	(	(	-LRB-
cord-329515-ra20actc	214	2	Fig	Fig	NNP
cord-329515-ra20actc	214	3	.	.	NNP
cord-329515-ra20actc	214	4	4	4	CD
cord-329515-ra20actc	214	5	c	c	NN
cord-329515-ra20actc	214	6	)	)	-RRB-
cord-329515-ra20actc	214	7	,	,	,
cord-329515-ra20actc	214	8	including	include	VBG
cord-329515-ra20actc	214	9	cells	cell	NNS
cord-329515-ra20actc	214	10	that	that	WDT
cord-329515-ra20actc	214	11	exhibit	exhibit	VBP
cord-329515-ra20actc	214	12	the	the	DT
cord-329515-ra20actc	214	13	striking	striking	JJ
cord-329515-ra20actc	214	14	tubular	tubular	JJ
cord-329515-ra20actc	214	15	network	network	NN
cord-329515-ra20actc	214	16	that	that	WDT
cord-329515-ra20actc	214	17	is	be	VBZ
cord-329515-ra20actc	214	18	typically	typically	RB
cord-329515-ra20actc	214	19	found	find	VBN
cord-329515-ra20actc	214	20	in	in	IN
cord-329515-ra20actc	214	21	p63wttransfected	p63wttransfected	JJ
cord-329515-ra20actc	214	22	ceils	ceil	NNS
cord-329515-ra20actc	214	23	(	(	-LRB-
cord-329515-ra20actc	214	24	Fig	Fig	NNP
cord-329515-ra20actc	214	25	.	.	.
cord-329515-ra20actc	214	26	4	4	CD
cord-329515-ra20actc	214	27	c	c	NN
cord-329515-ra20actc	214	28	,	,	,
cord-329515-ra20actc	214	29	inset	inset	NN
cord-329515-ra20actc	214	30	)	)	-RRB-
cord-329515-ra20actc	214	31	.	.	.
cord-329515-ra20actc	215	1	We	-PRON-	PRP
cord-329515-ra20actc	215	2	conclude	conclude	VBP
cord-329515-ra20actc	215	3	from	from	IN
cord-329515-ra20actc	215	4	these	these	DT
cord-329515-ra20actc	215	5	results	result	NNS
cord-329515-ra20actc	215	6	that	that	IN
cord-329515-ra20actc	215	7	the	the	DT
cord-329515-ra20actc	215	8	NH~-terminal	nh~-terminal	JJ
cord-329515-ra20actc	215	9	23	23	CD
cord-329515-ra20actc	215	10	amino	amino	NN
cord-329515-ra20actc	215	11	acid	acid	NN
cord-329515-ra20actc	215	12	residues	residue	NNS
cord-329515-ra20actc	215	13	of	of	IN
cord-329515-ra20actc	215	14	the	the	DT
cord-329515-ra20actc	215	15	p63	p63	CD
cord-329515-ra20actc	215	16	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	215	17	domain	domain	NN
cord-329515-ra20actc	215	18	are	be	VBP
cord-329515-ra20actc	215	19	required	require	VBN
cord-329515-ra20actc	215	20	for	for	IN
cord-329515-ra20actc	215	21	proper	proper	JJ
cord-329515-ra20actc	215	22	intracellular	intracellular	JJ
cord-329515-ra20actc	215	23	localization	localization	NN
cord-329515-ra20actc	215	24	.	.	.
cord-329515-ra20actc	216	1	Deletion	deletion	NN
cord-329515-ra20actc	216	2	of	of	IN
cord-329515-ra20actc	216	3	amino	amino	JJ
cord-329515-ra20actc	216	4	acids	acid	NNS
cord-329515-ra20actc	216	5	24	24	CD
cord-329515-ra20actc	216	6	-	-	SYM
cord-329515-ra20actc	216	7	101	101	CD
cord-329515-ra20actc	216	8	of	of	IN
cord-329515-ra20actc	216	9	the	the	DT
cord-329515-ra20actc	216	10	p63	p63	CD
cord-329515-ra20actc	216	11	tail	tail	NN
cord-329515-ra20actc	216	12	,	,	,
cord-329515-ra20actc	216	13	on	on	IN
cord-329515-ra20actc	216	14	the	the	DT
cord-329515-ra20actc	216	15	other	other	JJ
cord-329515-ra20actc	216	16	hand	hand	NN
cord-329515-ra20actc	216	17	,	,	,
cord-329515-ra20actc	216	18	had	have	VBD
cord-329515-ra20actc	216	19	no	no	DT
cord-329515-ra20actc	216	20	detectable	detectable	JJ
cord-329515-ra20actc	216	21	effect	effect	NN
cord-329515-ra20actc	216	22	on	on	IN
cord-329515-ra20actc	216	23	the	the	DT
cord-329515-ra20actc	216	24	distribution	distribution	NN
cord-329515-ra20actc	216	25	of	of	IN
cord-329515-ra20actc	216	26	p63	p63	CD
cord-329515-ra20actc	216	27	in	in	IN
cord-329515-ra20actc	216	28	the	the	DT
cord-329515-ra20actc	216	29	cell	cell	NN
cord-329515-ra20actc	216	30	.	.	.
cord-329515-ra20actc	217	1	To	to	TO
cord-329515-ra20actc	217	2	further	further	RB
cord-329515-ra20actc	217	3	define	define	VB
cord-329515-ra20actc	217	4	the	the	DT
cord-329515-ra20actc	217	5	sorting	sorting	NN
cord-329515-ra20actc	217	6	determinant	determinant	NN
cord-329515-ra20actc	217	7	that	that	WDT
cord-329515-ra20actc	217	8	is	be	VBZ
cord-329515-ra20actc	217	9	present	present	JJ
cord-329515-ra20actc	217	10	within	within	IN
cord-329515-ra20actc	217	11	amino	amino	JJ
cord-329515-ra20actc	217	12	acids	acid	NNS
cord-329515-ra20actc	217	13	1	1	CD
cord-329515-ra20actc	217	14	-	-	SYM
cord-329515-ra20actc	217	15	23	23	CD
cord-329515-ra20actc	217	16	of	of	IN
cord-329515-ra20actc	217	17	p63	p63	CD
cord-329515-ra20actc	217	18	,	,	,
cord-329515-ra20actc	217	19	this	this	DT
cord-329515-ra20actc	217	20	region	region	NN
cord-329515-ra20actc	217	21	was	be	VBD
cord-329515-ra20actc	217	22	subjected	subject	VBN
cord-329515-ra20actc	217	23	to	to	IN
cord-329515-ra20actc	217	24	extensive	extensive	JJ
cord-329515-ra20actc	217	25	site	site	NN
cord-329515-ra20actc	217	26	-	-	HYPH
cord-329515-ra20actc	217	27	directed	direct	VBN
cord-329515-ra20actc	217	28	mutagenesis	mutagenesis	NN
cord-329515-ra20actc	217	29	.	.	.
cord-329515-ra20actc	218	1	First	first	RB
cord-329515-ra20actc	218	2	,	,	,
cord-329515-ra20actc	218	3	a	a	DT
cord-329515-ra20actc	218	4	series	series	NN
cord-329515-ra20actc	218	5	of	of	IN
cord-329515-ra20actc	218	6	overlapping	overlap	VBG
cord-329515-ra20actc	218	7	alanine	alanine	NN
cord-329515-ra20actc	218	8	stretches	stretch	NNS
cord-329515-ra20actc	218	9	was	be	VBD
cord-329515-ra20actc	218	10	created	create	VBN
cord-329515-ra20actc	218	11	in	in	IN
cord-329515-ra20actc	218	12	the	the	DT
cord-329515-ra20actc	218	13	A24	A24	NNP
cord-329515-ra20actc	218	14	-	-	HYPH
cord-329515-ra20actc	218	15	101	101	CD
cord-329515-ra20actc	218	16	mutant	mutant	NN
cord-329515-ra20actc	218	17	.	.	.
cord-329515-ra20actc	219	1	As	as	IN
cord-329515-ra20actc	219	2	indicated	indicate	VBN
cord-329515-ra20actc	219	3	in	in	IN
cord-329515-ra20actc	219	4	Fig	Fig	NNP
cord-329515-ra20actc	219	5	.	.	.
cord-329515-ra20actc	220	1	5	5	LS
cord-329515-ra20actc	220	2	A	a	NN
cord-329515-ra20actc	220	3	,	,	,
cord-329515-ra20actc	220	4	amino	amino	JJ
cord-329515-ra20actc	220	5	acids	acid	NNS
cord-329515-ra20actc	220	6	2	2	CD
cord-329515-ra20actc	220	7	-	-	SYM
cord-329515-ra20actc	220	8	8	8	CD
cord-329515-ra20actc	220	9	(	(	-LRB-
cord-329515-ra20actc	220	10	A24	A24	NNP
cord-329515-ra20actc	220	11	-	-	HYPH
cord-329515-ra20actc	220	12	101	101	CD
cord-329515-ra20actc	220	13	,	,	,
cord-329515-ra20actc	220	14	2	2	CD
cord-329515-ra20actc	220	15	-	-	HYPH
cord-329515-ra20actc	220	16	8A	8a	NN
cord-329515-ra20actc	220	17	)	)	-RRB-
cord-329515-ra20actc	220	18	,	,	,
cord-329515-ra20actc	220	19	amino	amino	JJ
cord-329515-ra20actc	220	20	acids	acid	NNS
cord-329515-ra20actc	220	21	6	6	CD
cord-329515-ra20actc	220	22	-	-	SYM
cord-329515-ra20actc	220	23	12	12	CD
cord-329515-ra20actc	220	24	(	(	-LRB-
cord-329515-ra20actc	220	25	A24	A24	NNP
cord-329515-ra20actc	220	26	-	-	HYPH
cord-329515-ra20actc	220	27	101,6	101,6	CD
cord-329515-ra20actc	220	28	-	-	HYPH
cord-329515-ra20actc	220	29	12A	12a	CD
cord-329515-ra20actc	220	30	)	)	-RRB-
cord-329515-ra20actc	220	31	,	,	,
cord-329515-ra20actc	220	32	amino	amino	JJ
cord-329515-ra20actc	220	33	acids	acid	NNS
cord-329515-ra20actc	221	1	9	9	LS
cord-329515-ra20actc	221	2	-	-	SYM
cord-329515-ra20actc	221	3	15	15	CD
cord-329515-ra20actc	221	4	(	(	-LRB-
cord-329515-ra20actc	221	5	A24	A24	NNP
cord-329515-ra20actc	221	6	-	-	HYPH
cord-329515-ra20actc	221	7	101,9	101,9	CD
cord-329515-ra20actc	221	8	-	-	HYPH
cord-329515-ra20actc	221	9	15A	15a	CD
cord-329515-ra20actc	221	10	)	)	-RRB-
cord-329515-ra20actc	221	11	,	,	,
cord-329515-ra20actc	221	12	amino	amino	JJ
cord-329515-ra20actc	221	13	acids	acid	NNS
cord-329515-ra20actc	221	14	13	13	CD
cord-329515-ra20actc	221	15	-	-	SYM
cord-329515-ra20actc	221	16	19	19	CD
cord-329515-ra20actc	222	1	(	(	-LRB-
cord-329515-ra20actc	222	2	A24	A24	NNP
cord-329515-ra20actc	222	3	-	-	HYPH
cord-329515-ra20actc	222	4	101	101	CD
cord-329515-ra20actc	222	5	,	,	,
cord-329515-ra20actc	222	6	13	13	CD
cord-329515-ra20actc	222	7	-	-	SYM
cord-329515-ra20actc	222	8	19A	19a	CD
cord-329515-ra20actc	222	9	)	)	-RRB-
cord-329515-ra20actc	222	10	,	,	,
cord-329515-ra20actc	222	11	or	or	CC
cord-329515-ra20actc	222	12	amino	amino	JJ
cord-329515-ra20actc	222	13	acids	acid	NNS
cord-329515-ra20actc	222	14	17	17	CD
cord-329515-ra20actc	222	15	-	-	SYM
cord-329515-ra20actc	222	16	23	23	CD
cord-329515-ra20actc	223	1	(	(	-LRB-
cord-329515-ra20actc	223	2	A24	A24	NNP
cord-329515-ra20actc	223	3	-	-	HYPH
cord-329515-ra20actc	223	4	101	101	CD
cord-329515-ra20actc	223	5	,	,	,
cord-329515-ra20actc	223	6	17	17	CD
cord-329515-ra20actc	223	7	-	-	HYPH
cord-329515-ra20actc	223	8	23A	23a	NN
cord-329515-ra20actc	223	9	)	)	-RRB-
cord-329515-ra20actc	223	10	,	,	,
cord-329515-ra20actc	223	11	respectively	respectively	RB
cord-329515-ra20actc	223	12	,	,	,
cord-329515-ra20actc	223	13	were	be	VBD
cord-329515-ra20actc	223	14	simultaneously	simultaneously	RB
cord-329515-ra20actc	223	15	changed	change	VBN
cord-329515-ra20actc	223	16	to	to	IN
cord-329515-ra20actc	223	17	alanines	alanine	NNS
cord-329515-ra20actc	223	18	using	use	VBG
cord-329515-ra20actc	223	19	PCR	PCR	NNP
cord-329515-ra20actc	223	20	mutagenesis	mutagenesis	NN
cord-329515-ra20actc	223	21	.	.	.
cord-329515-ra20actc	224	1	Surprisingly	surprisingly	RB
cord-329515-ra20actc	224	2	,	,	,
cord-329515-ra20actc	224	3	these	these	DT
cord-329515-ra20actc	224	4	substitutions	substitution	NNS
cord-329515-ra20actc	224	5	had	have	VBD
cord-329515-ra20actc	224	6	no	no	DT
cord-329515-ra20actc	224	7	detectable	detectable	JJ
cord-329515-ra20actc	224	8	effect	effect	NN
cord-329515-ra20actc	224	9	on	on	IN
cord-329515-ra20actc	224	10	the	the	DT
cord-329515-ra20actc	224	11	localization	localization	NN
cord-329515-ra20actc	224	12	of	of	IN
cord-329515-ra20actc	224	13	p63	p63	CD
cord-329515-ra20actc	224	14	.	.	.
cord-329515-ra20actc	225	1	Immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	225	2	of	of	IN
cord-329515-ra20actc	225	3	transfected	transfecte	VBN
cord-329515-ra20actc	225	4	nonpermeabilized	nonpermeabilized	JJ
cord-329515-ra20actc	225	5	cells	cell	NNS
cord-329515-ra20actc	225	6	showed	show	VBD
cord-329515-ra20actc	225	7	that	that	IN
cord-329515-ra20actc	225	8	none	none	NN
cord-329515-ra20actc	225	9	of	of	IN
cord-329515-ra20actc	225	10	the	the	DT
cord-329515-ra20actc	225	11	mutants	mutant	NNS
cord-329515-ra20actc	225	12	were	be	VBD
cord-329515-ra20actc	225	13	transported	transport	VBN
cord-329515-ra20actc	225	14	to	to	IN
cord-329515-ra20actc	225	15	the	the	DT
cord-329515-ra20actc	225	16	plasma	plasma	NN
cord-329515-ra20actc	225	17	membrane	membrane	NN
cord-329515-ra20actc	225	18	(	(	-LRB-
cord-329515-ra20actc	225	19	for	for	IN
cord-329515-ra20actc	225	20	an	an	DT
cord-329515-ra20actc	225	21	example	example	NN
cord-329515-ra20actc	225	22	see	see	VBP
cord-329515-ra20actc	225	23	Fig	Fig	NNP
cord-329515-ra20actc	225	24	.	.	.
cord-329515-ra20actc	225	25	6	6	CD
cord-329515-ra20actc	225	26	b	b	NN
cord-329515-ra20actc	225	27	)	)	-RRB-
cord-329515-ra20actc	225	28	.	.	.
cord-329515-ra20actc	226	1	The	the	DT
cord-329515-ra20actc	226	2	internal	internal	JJ
cord-329515-ra20actc	226	3	distribution	distribution	NN
cord-329515-ra20actc	226	4	of	of	IN
cord-329515-ra20actc	226	5	the	the	DT
cord-329515-ra20actc	226	6	constructs	construct	NNS
cord-329515-ra20actc	226	7	was	be	VBD
cord-329515-ra20actc	226	8	also	also	RB
cord-329515-ra20actc	226	9	indistinguishable	indistinguishable	JJ
cord-329515-ra20actc	226	10	from	from	IN
cord-329515-ra20actc	226	11	that	that	DT
cord-329515-ra20actc	226	12	of/,24	of/,24	NN
cord-329515-ra20actc	226	13	-	-	HYPH
cord-329515-ra20actc	226	14	101	101	CD
cord-329515-ra20actc	226	15	or	or	CC
cord-329515-ra20actc	226	16	p63wt	p63wt	CD
cord-329515-ra20actc	227	1	(	(	-LRB-
cord-329515-ra20actc	227	2	for	for	IN
cord-329515-ra20actc	227	3	an	an	DT
cord-329515-ra20actc	227	4	example	example	NN
cord-329515-ra20actc	227	5	see	see	VBP
cord-329515-ra20actc	227	6	Fig	Fig	NNP
cord-329515-ra20actc	227	7	.	.	.
cord-329515-ra20actc	227	8	6	6	CD
cord-329515-ra20actc	227	9	a	a	LS
cord-329515-ra20actc	227	10	)	)	-RRB-
cord-329515-ra20actc	227	11	.	.	.
cord-329515-ra20actc	228	1	When	when	WRB
cord-329515-ra20actc	228	2	a	a	DT
cord-329515-ra20actc	228	3	similar	similar	JJ
cord-329515-ra20actc	228	4	type	type	NN
cord-329515-ra20actc	228	5	of	of	IN
cord-329515-ra20actc	228	6	alanine	alanine	NN
cord-329515-ra20actc	228	7	scan	scan	NN
cord-329515-ra20actc	228	8	was	be	VBD
cord-329515-ra20actc	228	9	carried	carry	VBN
cord-329515-ra20actc	228	10	out	out	RP
cord-329515-ra20actc	228	11	in	in	IN
cord-329515-ra20actc	228	12	the	the	DT
cord-329515-ra20actc	228	13	m6	m6	NNP
cord-329515-ra20actc	228	14	-	-	SYM
cord-329515-ra20actc	228	15	101	101	CD
cord-329515-ra20actc	228	16	background	background	NN
cord-329515-ra20actc	229	1	(	(	-LRB-
cord-329515-ra20actc	229	2	Fig	Fig	NNP
cord-329515-ra20actc	229	3	.	.	.
cord-329515-ra20actc	229	4	5	5	CD
cord-329515-ra20actc	229	5	B	b	NN
cord-329515-ra20actc	229	6	)	)	-RRB-
cord-329515-ra20actc	229	7	,	,	,
cord-329515-ra20actc	229	8	a	a	DT
cord-329515-ra20actc	229	9	different	different	JJ
cord-329515-ra20actc	229	10	result	result	NN
cord-329515-ra20actc	229	11	was	be	VBD
cord-329515-ra20actc	229	12	obtained	obtain	VBN
cord-329515-ra20actc	229	13	.	.	.
cord-329515-ra20actc	230	1	All	all	DT
cord-329515-ra20actc	230	2	of	of	IN
cord-329515-ra20actc	230	3	the	the	DT
cord-329515-ra20actc	230	4	mutant	mutant	JJ
cord-329515-ra20actc	230	5	proteins	protein	NNS
cord-329515-ra20actc	230	6	exhibited	exhibit	VBD
cord-329515-ra20actc	230	7	some	some	DT
cord-329515-ra20actc	230	8	degree	degree	NN
cord-329515-ra20actc	230	9	of	of	IN
cord-329515-ra20actc	230	10	increased	increase	VBN
cord-329515-ra20actc	230	11	transport	transport	NN
cord-329515-ra20actc	230	12	to	to	IN
cord-329515-ra20actc	230	13	the	the	DT
cord-329515-ra20actc	230	14	cell	cell	NN
cord-329515-ra20actc	230	15	surface	surface	NN
cord-329515-ra20actc	230	16	,	,	,
cord-329515-ra20actc	230	17	with	with	IN
cord-329515-ra20actc	230	18	the	the	DT
cord-329515-ra20actc	230	19	zk16	zk16	CD
cord-329515-ra20actc	230	20	-	-	HYPH
cord-329515-ra20actc	230	21	101,6	101,6	CD
cord-329515-ra20actc	230	22	-	-	HYPH
cord-329515-ra20actc	230	23	12A	12a	NN
cord-329515-ra20actc	230	24	mutant	mutant	NN
cord-329515-ra20actc	230	25	showing	show	VBG
cord-329515-ra20actc	230	26	the	the	DT
cord-329515-ra20actc	230	27	strongest	strong	JJS
cord-329515-ra20actc	230	28	effect	effect	NN
cord-329515-ra20actc	230	29	(	(	-LRB-
cord-329515-ra20actc	230	30	Fig	Fig	NNP
cord-329515-ra20actc	230	31	.	.	.
cord-329515-ra20actc	230	32	6	6	CD
cord-329515-ra20actc	230	33	d	d	NN
cord-329515-ra20actc	230	34	)	)	-RRB-
cord-329515-ra20actc	230	35	.	.	.
cord-329515-ra20actc	231	1	When	when	WRB
cord-329515-ra20actc	231	2	COS	cos	NN
cord-329515-ra20actc	231	3	cells	cell	NNS
cord-329515-ra20actc	231	4	transfected	transfecte	VBN
cord-329515-ra20actc	231	5	with	with	IN
cord-329515-ra20actc	231	6	this	this	DT
cord-329515-ra20actc	231	7	mutant	mutant	NN
cord-329515-ra20actc	231	8	were	be	VBD
cord-329515-ra20actc	231	9	permeabilized	permeabilized	JJ
cord-329515-ra20actc	231	10	,	,	,
cord-329515-ra20actc	231	11	the	the	DT
cord-329515-ra20actc	231	12	predominant	predominant	JJ
cord-329515-ra20actc	231	13	staining	staining	NN
cord-329515-ra20actc	231	14	pattern	pattern	NN
cord-329515-ra20actc	231	15	was	be	VBD
cord-329515-ra20actc	231	16	characteristic	characteristic	JJ
cord-329515-ra20actc	231	17	for	for	IN
cord-329515-ra20actc	231	18	the	the	DT
cord-329515-ra20actc	231	19	ER	ER	NNP
cord-329515-ra20actc	231	20	and	and	CC
cord-329515-ra20actc	231	21	the	the	DT
cord-329515-ra20actc	231	22	Golgi	Golgi	NNP
cord-329515-ra20actc	231	23	apparatus	apparatus	NN
cord-329515-ra20actc	231	24	indicating	indicate	VBG
cord-329515-ra20actc	232	1	that/,16	that/,16	NN
cord-329515-ra20actc	232	2	-	-	HYPH
cord-329515-ra20actc	232	3	101,6	101,6	CD
cord-329515-ra20actc	232	4	-	-	HYPH
cord-329515-ra20actc	232	5	12A	12A	NNP
cord-329515-ra20actc	232	6	had	have	VBD
cord-329515-ra20actc	232	7	lost	lose	VBN
cord-329515-ra20actc	232	8	p63wt	p63wt	CD
cord-329515-ra20actc	232	9	localization	localization	NN
cord-329515-ra20actc	232	10	(	(	-LRB-
cord-329515-ra20actc	232	11	Fig	Fig	NNP
cord-329515-ra20actc	232	12	.	.	.
cord-329515-ra20actc	232	13	6	6	CD
cord-329515-ra20actc	232	14	c	c	NN
cord-329515-ra20actc	232	15	)	)	-RRB-
cord-329515-ra20actc	232	16	.	.	.
cord-329515-ra20actc	233	1	These	these	DT
cord-329515-ra20actc	233	2	results	result	NNS
cord-329515-ra20actc	233	3	clearly	clearly	RB
cord-329515-ra20actc	233	4	show	show	VBP
cord-329515-ra20actc	233	5	that	that	IN
cord-329515-ra20actc	233	6	alanine	alanine	NN
cord-329515-ra20actc	233	7	substitutions	substitution	NNS
cord-329515-ra20actc	233	8	have	have	VBP
cord-329515-ra20actc	233	9	an	an	DT
cord-329515-ra20actc	233	10	effect	effect	NN
cord-329515-ra20actc	233	11	when	when	WRB
cord-329515-ra20actc	233	12	only	only	RB
cord-329515-ra20actc	233	13	amino	amino	JJ
cord-329515-ra20actc	233	14	acids	acid	NNS
cord-329515-ra20actc	233	15	1	1	CD
cord-329515-ra20actc	233	16	-	-	SYM
cord-329515-ra20actc	233	17	15	15	CD
cord-329515-ra20actc	233	18	(	(	-LRB-
cord-329515-ra20actc	233	19	/,16	/,16	NNP
cord-329515-ra20actc	233	20	-	-	:
cord-329515-ra20actc	233	21	101	101	CD
cord-329515-ra20actc	233	22	)	)	-RRB-
cord-329515-ra20actc	233	23	instead	instead	RB
cord-329515-ra20actc	233	24	of	of	IN
cord-329515-ra20actc	233	25	amino	amino	JJ
cord-329515-ra20actc	233	26	acids	acid	NNS
cord-329515-ra20actc	233	27	1	1	CD
cord-329515-ra20actc	233	28	-	-	SYM
cord-329515-ra20actc	233	29	23	23	CD
cord-329515-ra20actc	233	30	(	(	-LRB-
cord-329515-ra20actc	233	31	/,24	/,24	NNP
cord-329515-ra20actc	233	32	-	-	:
cord-329515-ra20actc	233	33	101	101	CD
cord-329515-ra20actc	233	34	)	)	-RRB-
cord-329515-ra20actc	233	35	of	of	IN
cord-329515-ra20actc	233	36	the	the	DT
cord-329515-ra20actc	233	37	p63	p63	CD
cord-329515-ra20actc	233	38	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	233	39	tail	tail	NN
cord-329515-ra20actc	233	40	are	be	VBP
cord-329515-ra20actc	233	41	present	present	JJ
cord-329515-ra20actc	233	42	.	.	.
cord-329515-ra20actc	234	1	One	one	CD
cord-329515-ra20actc	234	2	possible	possible	JJ
cord-329515-ra20actc	234	3	explanation	explanation	NN
cord-329515-ra20actc	234	4	for	for	IN
cord-329515-ra20actc	234	5	this	this	DT
cord-329515-ra20actc	234	6	finding	finding	NN
cord-329515-ra20actc	234	7	could	could	MD
cord-329515-ra20actc	234	8	be	be	VB
cord-329515-ra20actc	234	9	the	the	DT
cord-329515-ra20actc	234	10	existence	existence	NN
cord-329515-ra20actc	234	11	of	of	IN
cord-329515-ra20actc	234	12	a	a	DT
cord-329515-ra20actc	234	13	redundant	redundant	JJ
cord-329515-ra20actc	234	14	signal	signal	NN
cord-329515-ra20actc	234	15	with	with	IN
cord-329515-ra20actc	234	16	one	one	CD
cord-329515-ra20actc	234	17	of	of	IN
cord-329515-ra20actc	234	18	the	the	DT
cord-329515-ra20actc	234	19	components	component	NNS
cord-329515-ra20actc	234	20	being	be	VBG
cord-329515-ra20actc	234	21	located	locate	VBN
cord-329515-ra20actc	234	22	within	within	IN
cord-329515-ra20actc	234	23	residues	residue	NNS
cord-329515-ra20actc	234	24	16	16	CD
cord-329515-ra20actc	234	25	-	-	SYM
cord-329515-ra20actc	234	26	23	23	CD
cord-329515-ra20actc	234	27	.	.	.
cord-329515-ra20actc	235	1	When	when	WRB
cord-329515-ra20actc	235	2	we	-PRON-	PRP
cord-329515-ra20actc	235	3	carefully	carefully	RB
cord-329515-ra20actc	235	4	inspected	inspect	VBD
cord-329515-ra20actc	235	5	the	the	DT
cord-329515-ra20actc	235	6	critical	critical	JJ
cord-329515-ra20actc	235	7	p63	p63	CD
cord-329515-ra20actc	235	8	sequence	sequence	NN
cord-329515-ra20actc	235	9	,	,	,
cord-329515-ra20actc	235	10	a	a	DT
cord-329515-ra20actc	235	11	repetitive	repetitive	JJ
cord-329515-ra20actc	235	12	feature	feature	NN
cord-329515-ra20actc	235	13	consisting	consist	VBG
cord-329515-ra20actc	235	14	of	of	IN
cord-329515-ra20actc	235	15	a	a	DT
cord-329515-ra20actc	235	16	positively	positively	RB
cord-329515-ra20actc	235	17	charged	charge	VBN
cord-329515-ra20actc	235	18	amino	amino	NN
cord-329515-ra20actc	235	19	acid	acid	NN
cord-329515-ra20actc	235	20	followed	follow	VBN
cord-329515-ra20actc	235	21	by	by	IN
cord-329515-ra20actc	235	22	a	a	DT
cord-329515-ra20actc	235	23	glycine	glycine	NN
cord-329515-ra20actc	235	24	residue	residue	NN
cord-329515-ra20actc	235	25	became	become	VBD
cord-329515-ra20actc	235	26	apparent	apparent	JJ
cord-329515-ra20actc	235	27	.	.	.
cord-329515-ra20actc	236	1	The	the	DT
cord-329515-ra20actc	236	2	sequence	sequence	NN
cord-329515-ra20actc	236	3	contains	contain	VBZ
cord-329515-ra20actc	236	4	an	an	DT
cord-329515-ra20actc	236	5	arginine	arginine	NN
cord-329515-ra20actc	236	6	-	-	HYPH
cord-329515-ra20actc	236	7	glycine	glycine	NN
cord-329515-ra20actc	236	8	combination	combination	NN
cord-329515-ra20actc	236	9	at	at	IN
cord-329515-ra20actc	236	10	amino	amino	NN
cord-329515-ra20actc	236	11	acid	acid	NN
cord-329515-ra20actc	236	12	positions	position	NNS
cord-329515-ra20actc	236	13	7	7	CD
cord-329515-ra20actc	236	14	and	and	CC
cord-329515-ra20actc	236	15	8	8	CD
cord-329515-ra20actc	236	16	,	,	,
cord-329515-ra20actc	236	17	and	and	CC
cord-329515-ra20actc	236	18	two	two	CD
cord-329515-ra20actc	236	19	pairs	pair	NNS
cord-329515-ra20actc	236	20	of	of	IN
cord-329515-ra20actc	236	21	lysine	lysine	NN
cord-329515-ra20actc	236	22	-	-	HYPH
cord-329515-ra20actc	236	23	glycine	glycine	NN
cord-329515-ra20actc	236	24	at	at	IN
cord-329515-ra20actc	236	25	positions	position	NNS
cord-329515-ra20actc	236	26	10	10	CD
cord-329515-ra20actc	236	27	and	and	CC
cord-329515-ra20actc	236	28	11	11	CD
cord-329515-ra20actc	236	29	,	,	,
cord-329515-ra20actc	236	30	and	and	CC
cord-329515-ra20actc	236	31	21	21	CD
cord-329515-ra20actc	236	32	and	and	CC
cord-329515-ra20actc	236	33	22	22	CD
cord-329515-ra20actc	236	34	,	,	,
cord-329515-ra20actc	236	35	respectively	respectively	RB
cord-329515-ra20actc	236	36	.	.	.
cord-329515-ra20actc	237	1	In	in	IN
cord-329515-ra20actc	237	2	addition	addition	NN
cord-329515-ra20actc	237	3	,	,	,
cord-329515-ra20actc	237	4	there	there	EX
cord-329515-ra20actc	237	5	is	be	VBZ
cord-329515-ra20actc	237	6	a	a	DT
cord-329515-ra20actc	237	7	single	single	JJ
cord-329515-ra20actc	237	8	lysine	lysine	NN
cord-329515-ra20actc	237	9	residue	residue	NN
cord-329515-ra20actc	237	10	present	present	NN
cord-329515-ra20actc	237	11	at	at	IN
cord-329515-ra20actc	237	12	amino	amino	NN
cord-329515-ra20actc	237	13	acid	acid	NN
cord-329515-ra20actc	237	14	position	position	NN
cord-329515-ra20actc	237	15	5	5	CD
cord-329515-ra20actc	237	16	.	.	.
cord-329515-ra20actc	238	1	The	the	DT
cord-329515-ra20actc	238	2	distribution	distribution	NN
cord-329515-ra20actc	238	3	of	of	IN
cord-329515-ra20actc	238	4	these	these	DT
cord-329515-ra20actc	238	5	residues	residue	NNS
cord-329515-ra20actc	238	6	relative	relative	JJ
cord-329515-ra20actc	238	7	to	to	IN
cord-329515-ra20actc	238	8	the	the	DT
cord-329515-ra20actc	238	9	amino	amino	NN
cord-329515-ra20actc	238	10	acids	acid	NNS
cord-329515-ra20actc	238	11	altered	alter	VBN
cord-329515-ra20actc	238	12	in	in	IN
cord-329515-ra20actc	238	13	the	the	DT
cord-329515-ra20actc	238	14	overlapping	overlapping	JJ
cord-329515-ra20actc	238	15	alanine	alanine	NN
cord-329515-ra20actc	238	16	substitution	substitution	NN
cord-329515-ra20actc	238	17	experiments	experiment	NNS
cord-329515-ra20actc	238	18	was	be	VBD
cord-329515-ra20actc	238	19	consistent	consistent	JJ
cord-329515-ra20actc	238	20	with	with	IN
cord-329515-ra20actc	238	21	these	these	DT
cord-329515-ra20actc	238	22	residues	residue	NNS
cord-329515-ra20actc	238	23	serving	serve	VBG
cord-329515-ra20actc	238	24	as	as	IN
cord-329515-ra20actc	238	25	components	component	NNS
cord-329515-ra20actc	238	26	of	of	IN
cord-329515-ra20actc	238	27	a	a	DT
cord-329515-ra20actc	238	28	redundant	redundant	JJ
cord-329515-ra20actc	238	29	retention	retention	NN
cord-329515-ra20actc	238	30	signal	signal	NN
cord-329515-ra20actc	238	31	.	.	.
cord-329515-ra20actc	239	1	To	to	TO
cord-329515-ra20actc	239	2	test	test	VB
cord-329515-ra20actc	239	3	this	this	DT
cord-329515-ra20actc	239	4	possibility	possibility	NN
cord-329515-ra20actc	239	5	,	,	,
cord-329515-ra20actc	239	6	K	K	NNP
cord-329515-ra20actc	239	7	~	~	NFP
cord-329515-ra20actc	239	8	,	,	,
cord-329515-ra20actc	239	9	R	R	NNP
cord-329515-ra20actc	239	10	7	7	CD
cord-329515-ra20actc	239	11	,	,	,
cord-329515-ra20actc	239	12	G	G	NNP
cord-329515-ra20actc	239	13	s	s	NNP
cord-329515-ra20actc	239	14	,	,	,
cord-329515-ra20actc	239	15	K	K	NNP
cord-329515-ra20actc	239	16	1	1	CD
cord-329515-ra20actc	239	17	°	°	NNS
cord-329515-ra20actc	239	18	,	,	,
cord-329515-ra20actc	239	19	G	G	NNP
cord-329515-ra20actc	239	20	H	h	NN
cord-329515-ra20actc	239	21	,	,	,
cord-329515-ra20actc	239	22	K	K	NNP
cord-329515-ra20actc	239	23	21	21	CD
cord-329515-ra20actc	239	24	,	,	,
cord-329515-ra20actc	239	25	and	and	CC
cord-329515-ra20actc	239	26	G	G	NNP
cord-329515-ra20actc	239	27	22	22	CD
cord-329515-ra20actc	239	28	in	in	IN
cord-329515-ra20actc	239	29	the	the	DT
cord-329515-ra20actc	239	30	~24	~24	JJ
cord-329515-ra20actc	239	31	-	-	SYM
cord-329515-ra20actc	239	32	101	101	CD
cord-329515-ra20actc	239	33	sequence	sequence	NN
cord-329515-ra20actc	239	34	were	be	VBD
cord-329515-ra20actc	239	35	simultaneously	simultaneously	RB
cord-329515-ra20actc	239	36	changed	change	VBN
cord-329515-ra20actc	239	37	to	to	IN
cord-329515-ra20actc	239	38	aianines	aianines	NNP
cord-329515-ra20actc	239	39	(	(	-LRB-
cord-329515-ra20actc	239	40	Z~.4	z~.4	NN
cord-329515-ra20actc	239	41	-	-	HYPH
cord-329515-ra20actc	239	42	101,KSRTGSKI	101,ksrtgski	NN
cord-329515-ra20actc	239	43	°	°	NN
cord-329515-ra20actc	239	44	GnK2tGa2-A	GnK2tGa2-A	.
cord-329515-ra20actc	240	1	[	[	-LRB-
cord-329515-ra20actc	240	2	MP1	MP1	NNP
cord-329515-ra20actc	240	3	]	]	-RRB-
cord-329515-ra20actc	240	4	;	;	:
cord-329515-ra20actc	240	5	Fig	Fig	NNP
cord-329515-ra20actc	240	6	.	.	NNP
cord-329515-ra20actc	240	7	7	7	CD
cord-329515-ra20actc	240	8	)	)	-RRB-
cord-329515-ra20actc	240	9	.	.	.
cord-329515-ra20actc	241	1	Immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	241	2	analysis	analysis	NN
cord-329515-ra20actc	241	3	of	of	IN
cord-329515-ra20actc	241	4	this	this	DT
cord-329515-ra20actc	241	5	mutant	mutant	NN
cord-329515-ra20actc	241	6	expressed	express	VBN
cord-329515-ra20actc	241	7	in	in	IN
cord-329515-ra20actc	241	8	COS	COS	NNP
cord-329515-ra20actc	241	9	cells	cell	NNS
cord-329515-ra20actc	241	10	revealed	reveal	VBD
cord-329515-ra20actc	241	11	that	that	IN
cord-329515-ra20actc	241	12	it	-PRON-	PRP
cord-329515-ra20actc	241	13	was	be	VBD
cord-329515-ra20actc	241	14	highly	highly	RB
cord-329515-ra20actc	241	15	expressed	express	VBN
cord-329515-ra20actc	241	16	at	at	IN
cord-329515-ra20actc	241	17	the	the	DT
cord-329515-ra20actc	241	18	plasma	plasma	NN
cord-329515-ra20actc	241	19	membrane	membrane	NN
cord-329515-ra20actc	241	20	of	of	IN
cord-329515-ra20actc	241	21	non	non	JJ
cord-329515-ra20actc	241	22	-	-	JJ
cord-329515-ra20actc	241	23	permeab~	permeab~	JJ
cord-329515-ra20actc	241	24	transfected	transfecte	VBN
cord-329515-ra20actc	241	25	cells	cell	NNS
cord-329515-ra20actc	241	26	(	(	-LRB-
cord-329515-ra20actc	241	27	Fig	Fig	NNP
cord-329515-ra20actc	241	28	.	.	.
cord-329515-ra20actc	241	29	8	8	CD
cord-329515-ra20actc	241	30	b	b	NN
cord-329515-ra20actc	241	31	)	)	-RRB-
cord-329515-ra20actc	241	32	.	.	.
cord-329515-ra20actc	242	1	Furthermore	furthermore	RB
cord-329515-ra20actc	242	2	,	,	,
cord-329515-ra20actc	242	3	in	in	IN
cord-329515-ra20actc	242	4	permeabilized	permeabilized	JJ
cord-329515-ra20actc	242	5	ceils	ceil	NNS
cord-329515-ra20actc	242	6	transfected	transfecte	VBN
cord-329515-ra20actc	242	7	with	with	IN
cord-329515-ra20actc	242	8	MP1	MP1	NNP
cord-329515-ra20actc	242	9	the	the	DT
cord-329515-ra20actc	242	10	staining	staining	NN
cord-329515-ra20actc	242	11	was	be	VBD
cord-329515-ra20actc	242	12	also	also	RB
cord-329515-ra20actc	242	13	characteristic	characteristic	JJ
cord-329515-ra20actc	242	14	for	for	IN
cord-329515-ra20actc	242	15	a	a	DT
cord-329515-ra20actc	242	16	surface	surface	NN
cord-329515-ra20actc	242	17	protein	protein	NN
cord-329515-ra20actc	242	18	(	(	-LRB-
cord-329515-ra20actc	242	19	Fig	Fig	NNP
cord-329515-ra20actc	242	20	.	.	.
cord-329515-ra20actc	242	21	8	8	CD
cord-329515-ra20actc	242	22	a	a	DT
cord-329515-ra20actc	242	23	)	)	-RRB-
cord-329515-ra20actc	242	24	.	.	.
cord-329515-ra20actc	243	1	The	the	DT
cord-329515-ra20actc	243	2	phenotype	phenotype	NN
cord-329515-ra20actc	243	3	of	of	IN
cord-329515-ra20actc	243	4	MP1	MP1	NNP
cord-329515-ra20actc	243	5	is	be	VBZ
cord-329515-ra20actc	243	6	therefore	therefore	RB
cord-329515-ra20actc	243	7	very	very	RB
cord-329515-ra20actc	243	8	similar	similar	JJ
cord-329515-ra20actc	243	9	to	to	IN
cord-329515-ra20actc	243	10	that	that	DT
cord-329515-ra20actc	243	11	of	of	IN
cord-329515-ra20actc	243	12	the	the	DT
cord-329515-ra20actc	243	13	tailminus	tailminus	NNP
cord-329515-ra20actc	243	14	mutant	mutant	NNP
cord-329515-ra20actc	243	15	A2	A2	NNP
cord-329515-ra20actc	243	16	-	-	HYPH
cord-329515-ra20actc	243	17	101AA	101AA	NNP
cord-329515-ra20actc	243	18	.	.	.
cord-329515-ra20actc	244	1	We	-PRON-	PRP
cord-329515-ra20actc	244	2	next	next	RB
cord-329515-ra20actc	244	3	tested	test	VBD
cord-329515-ra20actc	244	4	whether	whether	IN
cord-329515-ra20actc	244	5	alunine	alunine	NN
cord-329515-ra20actc	244	6	substitutions	substitution	NNS
cord-329515-ra20actc	244	7	of	of	IN
cord-329515-ra20actc	244	8	only	only	RB
cord-329515-ra20actc	244	9	the	the	DT
cord-329515-ra20actc	244	10	positively	positively	RB
cord-329515-ra20actc	244	11	charged	charge	VBN
cord-329515-ra20actc	244	12	amino	amino	NN
cord-329515-ra20actc	244	13	acids	acid	NNS
cord-329515-ra20actc	244	14	(	(	-LRB-
cord-329515-ra20actc	244	15	K	K	NNP
cord-329515-ra20actc	244	16	s	s	NNP
cord-329515-ra20actc	244	17	,	,	,
cord-329515-ra20actc	244	18	W	W	NNP
cord-329515-ra20actc	244	19	,	,	,
cord-329515-ra20actc	244	20	K	K	NNP
cord-329515-ra20actc	244	21	1	1	CD
cord-329515-ra20actc	244	22	°	°	NNS
cord-329515-ra20actc	244	23	,	,	,
cord-329515-ra20actc	244	24	and	and	CC
cord-329515-ra20actc	244	25	K29	K29	NNP
cord-329515-ra20actc	244	26	(	(	-LRB-
cord-329515-ra20actc	244	27	A24	A24	NNP
cord-329515-ra20actc	244	28	-	-	HYPH
cord-329515-ra20actc	244	29	101,KSRTK'	101,ksrtk'	CD
cord-329515-ra20actc	244	30	°	°	NN
cord-329515-ra20actc	244	31	Ke~-A	Ke~-A	NNS
cord-329515-ra20actc	244	32	[	[	-LRB-
cord-329515-ra20actc	244	33	MF2	MF2	NNP
cord-329515-ra20actc	244	34	]	]	-RRB-
cord-329515-ra20actc	244	35	;	;	:
cord-329515-ra20actc	244	36	Fig	Fig	NNP
cord-329515-ra20actc	244	37	.	.	NNP
cord-329515-ra20actc	244	38	7	7	CD
cord-329515-ra20actc	244	39	)	)	-RRB-
cord-329515-ra20actc	244	40	or	or	CC
cord-329515-ra20actc	244	41	only	only	RB
cord-329515-ra20actc	244	42	the	the	DT
cord-329515-ra20actc	244	43	glycine	glycine	NN
cord-329515-ra20actc	244	44	residues	residue	NNS
cord-329515-ra20actc	244	45	(	(	-LRB-
cord-329515-ra20actc	244	46	C_J	c_j	JJ
cord-329515-ra20actc	244	47	,	,	,
cord-329515-ra20actc	244	48	G	G	NNP
cord-329515-ra20actc	244	49	n	n	NN
cord-329515-ra20actc	244	50	,	,	,
cord-329515-ra20actc	244	51	and	and	CC
cord-329515-ra20actc	244	52	Cr	Cr	NNP
cord-329515-ra20actc	244	53	n	n	NN
cord-329515-ra20actc	244	54	)	)	-RRB-
cord-329515-ra20actc	244	55	(	(	-LRB-
cord-329515-ra20actc	244	56	A94	A94	NNP
cord-329515-ra20actc	244	57	-	-	HYPH
cord-329515-ra20actc	244	58	101,CJG"G22-A	101,cjg"g22-a	CD
cord-329515-ra20actc	245	1	[	[	-LRB-
cord-329515-ra20actc	245	2	MP3	mp3	NN
cord-329515-ra20actc	245	3	]	]	-RRB-
cord-329515-ra20actc	245	4	;	;	:
cord-329515-ra20actc	245	5	Fig	Fig	NNP
cord-329515-ra20actc	245	6	.	.	.
cord-329515-ra20actc	246	1	7	7	LS
cord-329515-ra20actc	246	2	)	)	-RRB-
cord-329515-ra20actc	246	3	present	present	JJ
cord-329515-ra20actc	246	4	in	in	IN
cord-329515-ra20actc	246	5	the	the	DT
cord-329515-ra20actc	246	6	K	K	NNP
cord-329515-ra20actc	246	7	-	-	HYPH
cord-329515-ra20actc	246	8	RG	RG	NNP
cord-329515-ra20actc	246	9	-	-	HYPH
cord-329515-ra20actc	246	10	KG	KG	NNP
cord-329515-ra20actc	246	11	-	-	HYPH
cord-329515-ra20actc	246	12	KG	KG	NNP
cord-329515-ra20actc	246	13	element	element	NN
cord-329515-ra20actc	246	14	would	would	MD
cord-329515-ra20actc	246	15	also	also	RB
cord-329515-ra20actc	246	16	disrupt	disrupt	VB
cord-329515-ra20actc	246	17	p63	p63	CD
cord-329515-ra20actc	246	18	localization	localization	NN
cord-329515-ra20actc	246	19	.	.	.
cord-329515-ra20actc	247	1	Both	both	DT
cord-329515-ra20actc	247	2	constructs	construct	NNS
cord-329515-ra20actc	247	3	behaved	behave	VBD
cord-329515-ra20actc	247	4	similarly	similarly	RB
cord-329515-ra20actc	247	5	to	to	IN
cord-329515-ra20actc	247	6	A24	A24	NNP
cord-329515-ra20actc	247	7	-	-	HYPH
cord-329515-ra20actc	247	8	101	101	CD
cord-329515-ra20actc	248	1	and	and	CC
cord-329515-ra20actc	248	2	p63wt	p63wt	NNP
cord-329515-ra20actc	248	3	as	as	IN
cord-329515-ra20actc	248	4	indicated	indicate	VBN
cord-329515-ra20actc	248	5	by	by	IN
cord-329515-ra20actc	248	6	the	the	DT
cord-329515-ra20actc	248	7	lack	lack	NN
cord-329515-ra20actc	248	8	of	of	IN
cord-329515-ra20actc	248	9	cell	cell	NN
cord-329515-ra20actc	248	10	surface	surface	NN
cord-329515-ra20actc	248	11	staining	staining	NN
cord-329515-ra20actc	248	12	(	(	-LRB-
cord-329515-ra20actc	248	13	Fig	fig	NN
cord-329515-ra20actc	248	14	.	.	.
cord-329515-ra20actc	249	1	8	8	CD
cord-329515-ra20actc	249	2	,	,	,
cord-329515-ra20actc	249	3	d	d	NN
cord-329515-ra20actc	249	4	and	and	CC
cord-329515-ra20actc	249	5	f	f	NNP
cord-329515-ra20actc	249	6	)	)	-RRB-
cord-329515-ra20actc	249	7	and	and	CC
cord-329515-ra20actc	249	8	the	the	DT
cord-329515-ra20actc	249	9	typical	typical	JJ
cord-329515-ra20actc	249	10	internal	internal	JJ
cord-329515-ra20actc	249	11	pattern	pattern	NN
cord-329515-ra20actc	249	12	(	(	-LRB-
cord-329515-ra20actc	249	13	Fig	Fig	NNP
cord-329515-ra20actc	249	14	.	.	NNP
cord-329515-ra20actc	249	15	8	8	CD
cord-329515-ra20actc	249	16	,	,	,
cord-329515-ra20actc	249	17	c	c	NN
cord-329515-ra20actc	249	18	and	and	CC
cord-329515-ra20actc	249	19	e	e	LS
cord-329515-ra20actc	249	20	)	)	-RRB-
cord-329515-ra20actc	249	21	.	.	.
cord-329515-ra20actc	250	1	This	this	DT
cord-329515-ra20actc	250	2	demonstrated	demonstrate	VBD
cord-329515-ra20actc	250	3	that	that	IN
cord-329515-ra20actc	250	4	changing	change	VBG
cord-329515-ra20actc	250	5	positive	positive	JJ
cord-329515-ra20actc	250	6	charges	charge	NNS
cord-329515-ra20actc	250	7	or	or	CC
cord-329515-ra20actc	250	8	glycines	glycine	NNS
cord-329515-ra20actc	250	9	alone	alone	RB
cord-329515-ra20actc	250	10	does	do	VBZ
cord-329515-ra20actc	250	11	not	not	RB
cord-329515-ra20actc	250	12	affect	affect	VB
cord-329515-ra20actc	250	13	retention	retention	NN
cord-329515-ra20actc	250	14	of	of	IN
cord-329515-ra20actc	250	15	p63	p63	CD
cord-329515-ra20actc	250	16	.	.	.
cord-329515-ra20actc	251	1	An	an	DT
cord-329515-ra20actc	251	2	additional	additional	JJ
cord-329515-ra20actc	251	3	construct	construct	NN
cord-329515-ra20actc	251	4	was	be	VBD
cord-329515-ra20actc	251	5	created	create	VBN
cord-329515-ra20actc	251	6	that	that	WDT
cord-329515-ra20actc	251	7	has	have	VBZ
cord-329515-ra20actc	251	8	the	the	DT
cord-329515-ra20actc	251	9	same	same	JJ
cord-329515-ra20actc	251	10	mutation	mutation	NN
cord-329515-ra20actc	251	11	as	as	IN
cord-329515-ra20actc	251	12	MP1	MP1	NNP
cord-329515-ra20actc	251	13	except	except	IN
cord-329515-ra20actc	251	14	for	for	IN
cord-329515-ra20actc	251	15	amino	amino	NN
cord-329515-ra20actc	251	16	acid	acid	NN
cord-329515-ra20actc	251	17	position	position	NN
cord-329515-ra20actc	251	18	5	5	CD
cord-329515-ra20actc	251	19	where	where	WRB
cord-329515-ra20actc	251	20	the	the	DT
cord-329515-ra20actc	251	21	original	original	JJ
cord-329515-ra20actc	251	22	lysine	lysine	NN
cord-329515-ra20actc	251	23	was	be	VBD
cord-329515-ra20actc	251	24	retained	retain	VBN
cord-329515-ra20actc	251	25	(	(	-LRB-
cord-329515-ra20actc	251	26	A94	A94	NNP
cord-329515-ra20actc	251	27	-	-	HYPH
cord-329515-ra20actc	251	28	101	101	CD
cord-329515-ra20actc	251	29	,	,	,
cord-329515-ra20actc	251	30	RTG	RTG	NNP
cord-329515-ra20actc	251	31	-	-	HYPH
cord-329515-ra20actc	251	32	SKt0GttK2tC_F'-A	SKt0GttK2tC_F'-A	NNP
cord-329515-ra20actc	251	33	[	[	-LRB-
cord-329515-ra20actc	251	34	MP4	mp4	NN
cord-329515-ra20actc	251	35	]	]	-RRB-
cord-329515-ra20actc	251	36	;	;	:
cord-329515-ra20actc	251	37	Fig	Fig	NNP
cord-329515-ra20actc	251	38	.	.	NNP
cord-329515-ra20actc	251	39	7	7	CD
cord-329515-ra20actc	251	40	)	)	-RRB-
cord-329515-ra20actc	251	41	.	.	.
cord-329515-ra20actc	252	1	Following	follow	VBG
cord-329515-ra20actc	252	2	transient	transient	JJ
cord-329515-ra20actc	252	3	transfection	transfection	NN
cord-329515-ra20actc	252	4	and	and	CC
cord-329515-ra20actc	252	5	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	252	6	microscopy	microscopy	NN
cord-329515-ra20actc	252	7	,	,	,
cord-329515-ra20actc	252	8	this	this	DT
cord-329515-ra20actc	252	9	mutant	mutant	NN
cord-329515-ra20actc	252	10	showed	show	VBD
cord-329515-ra20actc	252	11	two	two	CD
cord-329515-ra20actc	252	12	different	different	JJ
cord-329515-ra20actc	252	13	localizations	localization	NNS
cord-329515-ra20actc	252	14	.	.	.
cord-329515-ra20actc	253	1	Some	some	DT
cord-329515-ra20actc	253	2	of	of	IN
cord-329515-ra20actc	253	3	the	the	DT
cord-329515-ra20actc	253	4	chimeric	chimeric	JJ
cord-329515-ra20actc	253	5	protein	protein	NN
cord-329515-ra20actc	253	6	was	be	VBD
cord-329515-ra20actc	253	7	consistenfly	consistenfly	NN
cord-329515-ra20actc	253	8	detected	detect	VBN
cord-329515-ra20actc	253	9	on	on	IN
cord-329515-ra20actc	253	10	the	the	DT
cord-329515-ra20actc	253	11	cell	cell	NN
cord-329515-ra20actc	253	12	surface	surface	NN
cord-329515-ra20actc	253	13	(	(	-LRB-
cord-329515-ra20actc	253	14	Fig	Fig	NNP
cord-329515-ra20actc	253	15	.	.	.
cord-329515-ra20actc	253	16	8	8	CD
cord-329515-ra20actc	253	17	h	h	NN
cord-329515-ra20actc	253	18	)	)	-RRB-
cord-329515-ra20actc	253	19	while	while	IN
cord-329515-ra20actc	253	20	the	the	DT
cord-329515-ra20actc	253	21	rernaining	rernaining	NN
cord-329515-ra20actc	253	22	protein	protein	NN
cord-329515-ra20actc	253	23	was	be	VBD
cord-329515-ra20actc	253	24	predominantly	predominantly	RB
cord-329515-ra20actc	253	25	found	find	VBN
cord-329515-ra20actc	253	26	in	in	IN
cord-329515-ra20actc	253	27	the	the	DT
cord-329515-ra20actc	253	28	ER	er	NN
cord-329515-ra20actc	253	29	(	(	-LRB-
cord-329515-ra20actc	253	30	Fig	fig	NN
cord-329515-ra20actc	253	31	.	.	.
cord-329515-ra20actc	254	1	8	8	CD
cord-329515-ra20actc	254	2	 	 	_SP
cord-329515-ra20actc	254	3	g	g	NN
cord-329515-ra20actc	254	4	)	)	-RRB-
cord-329515-ra20actc	254	5	.	.	.
cord-329515-ra20actc	255	1	The	the	DT
cord-329515-ra20actc	255	2	latter	latter	JJ
cord-329515-ra20actc	255	3	finding	finding	NN
cord-329515-ra20actc	255	4	suggested	suggest	VBD
cord-329515-ra20actc	255	5	that	that	IN
cord-329515-ra20actc	255	6	the	the	DT
cord-329515-ra20actc	255	7	introduced	introduce	VBN
cord-329515-ra20actc	255	8	changes	change	NNS
cord-329515-ra20actc	255	9	might	may	MD
cord-329515-ra20actc	255	10	partly	partly	RB
cord-329515-ra20actc	255	11	impair	impair	VB
cord-329515-ra20actc	255	12	proper	proper	JJ
cord-329515-ra20actc	255	13	folding	folding	NN
cord-329515-ra20actc	255	14	of	of	IN
cord-329515-ra20actc	255	15	the	the	DT
cord-329515-ra20actc	255	16	mutant	mutant	JJ
cord-329515-ra20actc	255	17	protein	protein	NN
cord-329515-ra20actc	255	18	which	which	WDT
cord-329515-ra20actc	255	19	may	may	MD
cord-329515-ra20actc	255	20	prevent	prevent	VB
cord-329515-ra20actc	255	21	its	-PRON-	PRP$
cord-329515-ra20actc	255	22	exit	exit	NN
cord-329515-ra20actc	255	23	from	from	IN
cord-329515-ra20actc	255	24	the	the	DT
cord-329515-ra20actc	255	25	ER	ER	NNP
cord-329515-ra20actc	255	26	.	.	.
cord-329515-ra20actc	256	1	The	the	DT
cord-329515-ra20actc	256	2	presence	presence	NN
cord-329515-ra20actc	256	3	of	of	IN
cord-329515-ra20actc	256	4	MP4	mp4	NN
cord-329515-ra20actc	256	5	at	at	IN
cord-329515-ra20actc	256	6	the	the	DT
cord-329515-ra20actc	256	7	cell	cell	NN
cord-329515-ra20actc	256	8	surface	surface	NN
cord-329515-ra20actc	256	9	shows	show	VBZ
cord-329515-ra20actc	256	10	that	that	IN
cord-329515-ra20actc	256	11	K	K	NNP
cord-329515-ra20actc	256	12	5	5	CD
cord-329515-ra20actc	256	13	can	can	MD
cord-329515-ra20actc	256	14	not	not	RB
cord-329515-ra20actc	256	15	restore	restore	VB
cord-329515-ra20actc	256	16	correct	correct	JJ
cord-329515-ra20actc	256	17	localization	localization	NN
cord-329515-ra20actc	256	18	of	of	IN
cord-329515-ra20actc	256	19	p63	p63	CD
cord-329515-ra20actc	256	20	in	in	IN
cord-329515-ra20actc	256	21	the	the	DT
cord-329515-ra20actc	256	22	absence	absence	NN
cord-329515-ra20actc	256	23	of	of	IN
cord-329515-ra20actc	256	24	the	the	DT
cord-329515-ra20actc	256	25	three	three	CD
cord-329515-ra20actc	256	26	positively	positively	RB
cord-329515-ra20actc	256	27	charged	charge	VBN
cord-329515-ra20actc	256	28	amino	amino	NN
cord-329515-ra20actc	256	29	acid	acid	NN
cord-329515-ra20actc	256	30	-	-	HYPH
cord-329515-ra20actc	256	31	glycine	glycine	NN
cord-329515-ra20actc	256	32	combinations	combination	NNS
cord-329515-ra20actc	256	33	.	.	.
cord-329515-ra20actc	257	1	To	to	TO
cord-329515-ra20actc	257	2	further	further	RB
cord-329515-ra20actc	257	3	analyze	analyze	VB
cord-329515-ra20actc	257	4	the	the	DT
cord-329515-ra20actc	257	5	role	role	NN
cord-329515-ra20actc	257	6	of	of	IN
cord-329515-ra20actc	257	7	the	the	DT
cord-329515-ra20actc	257	8	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	257	9	tail	tail	NN
cord-329515-ra20actc	257	10	of	of	IN
cord-329515-ra20actc	257	11	p63	p63	CD
cord-329515-ra20actc	257	12	in	in	IN
cord-329515-ra20actc	257	13	retention	retention	NN
cord-329515-ra20actc	257	14	and	and	CC
cord-329515-ra20actc	257	15	to	to	TO
cord-329515-ra20actc	257	16	determine	determine	VB
cord-329515-ra20actc	257	17	whether	whether	IN
cord-329515-ra20actc	257	18	the	the	DT
cord-329515-ra20actc	257	19	transmembrane	transmembrane	NN
cord-329515-ra20actc	257	20	and	and	CC
cord-329515-ra20actc	257	21	lumenal	lumenal	JJ
cord-329515-ra20actc	257	22	domains	domain	NNS
cord-329515-ra20actc	257	23	of	of	IN
cord-329515-ra20actc	257	24	this	this	DT
cord-329515-ra20actc	257	25	protein	protein	NN
cord-329515-ra20actc	257	26	contribute	contribute	VBP
cord-329515-ra20actc	257	27	to	to	IN
cord-329515-ra20actc	257	28	proper	proper	JJ
cord-329515-ra20actc	257	29	intracellular	intracellular	JJ
cord-329515-ra20actc	257	30	localization	localization	NN
cord-329515-ra20actc	257	31	,	,	,
cord-329515-ra20actc	257	32	we	-PRON-	PRP
cord-329515-ra20actc	257	33	substituted	substitute	VBD
cord-329515-ra20actc	257	34	each	each	DT
cord-329515-ra20actc	257	35	of	of	IN
cord-329515-ra20actc	257	36	these	these	DT
cord-329515-ra20actc	257	37	domains	domain	NNS
cord-329515-ra20actc	257	38	with	with	IN
cord-329515-ra20actc	257	39	the	the	DT
cord-329515-ra20actc	257	40	corresponding	correspond	VBG
cord-329515-ra20actc	257	41	domains	domain	NNS
cord-329515-ra20actc	257	42	of	of	IN
cord-329515-ra20actc	257	43	the	the	DT
cord-329515-ra20actc	257	44	cell	cell	NN
cord-329515-ra20actc	257	45	surface	surface	NN
cord-329515-ra20actc	257	46	protein	protein	NN
cord-329515-ra20actc	257	47	human	human	JJ
cord-329515-ra20actc	257	48	DPPIV	DPPIV	NNP
cord-329515-ra20actc	257	49	(	(	-LRB-
cord-329515-ra20actc	257	50	Fig	Fig	NNP
cord-329515-ra20actc	257	51	.	.	.
cord-329515-ra20actc	257	52	9	9	CD
cord-329515-ra20actc	257	53	)	)	-RRB-
cord-329515-ra20actc	257	54	.	.	.
cord-329515-ra20actc	258	1	The	the	DT
cord-329515-ra20actc	258	2	serine	serine	NN
cord-329515-ra20actc	258	3	protease	protease	NN
cord-329515-ra20actc	258	4	DPPIV	DPPIV	NNP
cord-329515-ra20actc	258	5	is	be	VBZ
cord-329515-ra20actc	258	6	a	a	DT
cord-329515-ra20actc	258	7	type	type	NN
cord-329515-ra20actc	258	8	II	ii	CD
cord-329515-ra20actc	258	9	integral	integral	JJ
cord-329515-ra20actc	258	10	membrane	membrane	NN
cord-329515-ra20actc	258	11	protein	protein	NN
cord-329515-ra20actc	258	12	like	like	IN
cord-329515-ra20actc	258	13	p63	p63	NN
cord-329515-ra20actc	258	14	and	and	CC
cord-329515-ra20actc	258	15	is	be	VBZ
cord-329515-ra20actc	258	16	found	find	VBN
cord-329515-ra20actc	258	17	on	on	IN
cord-329515-ra20actc	258	18	a	a	DT
cord-329515-ra20actc	258	19	variety	variety	NN
cord-329515-ra20actc	258	20	of	of	IN
cord-329515-ra20actc	258	21	epithelial	epithelial	JJ
cord-329515-ra20actc	258	22	,	,	,
cord-329515-ra20actc	258	23	endothelial	endothelial	JJ
cord-329515-ra20actc	258	24	and	and	CC
cord-329515-ra20actc	258	25	lymphocytic	lymphocytic	JJ
cord-329515-ra20actc	258	26	cell	cell	NN
cord-329515-ra20actc	258	27	types	type	NNS
cord-329515-ra20actc	258	28	Doyle	Doyle	NNP
cord-329515-ra20actc	258	29	,	,	,
cord-329515-ra20actc	258	30	1987	1987	CD
cord-329515-ra20actc	258	31	,	,	,
cord-329515-ra20actc	258	32	1990	1990	CD
cord-329515-ra20actc	258	33	;	;	:
cord-329515-ra20actc	258	34	Ogata	Ogata	NNP
cord-329515-ra20actc	258	35	et	et	NNP
cord-329515-ra20actc	258	36	al	al	NNP
cord-329515-ra20actc	258	37	.	.	NNP
cord-329515-ra20actc	258	38	,	,	,
cord-329515-ra20actc	258	39	1989	1989	CD
cord-329515-ra20actc	258	40	)	)	-RRB-
cord-329515-ra20actc	258	41	.	.	.
cord-329515-ra20actc	259	1	We	-PRON-	PRP
cord-329515-ra20actc	259	2	first	first	RB
cord-329515-ra20actc	259	3	analyzed	analyze	VBD
cord-329515-ra20actc	259	4	a	a	DT
cord-329515-ra20actc	259	5	chimeric	chimeric	JJ
cord-329515-ra20actc	259	6	protein	protein	NN
cord-329515-ra20actc	259	7	(	(	-LRB-
cord-329515-ra20actc	259	8	DPP	DPP	NNP
cord-329515-ra20actc	259	9	;	;	:
cord-329515-ra20actc	259	10	DPPIV	DPPIV	NNP
cord-329515-ra20actc	259	11	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	259	12	,	,	,
cord-329515-ra20actc	259	13	p63	p63	NN
cord-329515-ra20actc	259	14	transmembrane	transmembrane	NN
cord-329515-ra20actc	259	15	,	,	,
cord-329515-ra20actc	259	16	p63	p63	NNP
cord-329515-ra20actc	259	17	lumenal	lumenal	NNP
cord-329515-ra20actc	259	18	;	;	:
cord-329515-ra20actc	259	19	Fig	Fig	NNP
cord-329515-ra20actc	259	20	.	.	.
cord-329515-ra20actc	259	21	9	9	CD
cord-329515-ra20actc	259	22	)	)	-RRB-
cord-329515-ra20actc	259	23	in	in	IN
cord-329515-ra20actc	259	24	which	which	WDT
cord-329515-ra20actc	259	25	the	the	DT
cord-329515-ra20actc	259	26	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	259	27	tall	tall	JJ
cord-329515-ra20actc	259	28	of	of	IN
cord-329515-ra20actc	259	29	DPPIV	DPPIV	NNP
cord-329515-ra20actc	259	30	was	be	VBD
cord-329515-ra20actc	259	31	fused	fuse	VBN
cord-329515-ra20actc	259	32	to	to	IN
cord-329515-ra20actc	259	33	the	the	DT
cord-329515-ra20actc	259	34	transmembrane	transmembrane	NN
cord-329515-ra20actc	259	35	and	and	CC
cord-329515-ra20actc	259	36	lumenal	lumenal	JJ
cord-329515-ra20actc	259	37	domains	domain	NNS
cord-329515-ra20actc	259	38	of	of	IN
cord-329515-ra20actc	259	39	p63	p63	CD
cord-329515-ra20actc	259	40	.	.	.
cord-329515-ra20actc	260	1	COS	COS	NNP
cord-329515-ra20actc	260	2	cells	cell	NNS
cord-329515-ra20actc	260	3	were	be	VBD
cord-329515-ra20actc	260	4	transfected	transfecte	VBN
cord-329515-ra20actc	260	5	with	with	IN
cord-329515-ra20actc	260	6	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	260	7	or	or	CC
cord-329515-ra20actc	261	1	the	the	DT
cord-329515-ra20actc	261	2	chimeric	chimeric	JJ
cord-329515-ra20actc	261	3	construct	construct	NN
cord-329515-ra20actc	261	4	and	and	CC
cord-329515-ra20actc	261	5	the	the	DT
cord-329515-ra20actc	261	6	localization	localization	NN
cord-329515-ra20actc	261	7	of	of	IN
cord-329515-ra20actc	261	8	the	the	DT
cord-329515-ra20actc	261	9	proteins	protein	NNS
cord-329515-ra20actc	261	10	was	be	VBD
cord-329515-ra20actc	261	11	examined	examine	VBN
cord-329515-ra20actc	261	12	by	by	IN
cord-329515-ra20actc	261	13	indirect	indirect	JJ
cord-329515-ra20actc	261	14	immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	261	15	of	of	IN
cord-329515-ra20actc	261	16	permeabilized	permeabilized	JJ
cord-329515-ra20actc	261	17	and	and	CC
cord-329515-ra20actc	261	18	nonpermeabilized	nonpermeabilized	JJ
cord-329515-ra20actc	261	19	cells	cell	NNS
cord-329515-ra20actc	261	20	using	use	VBG
cord-329515-ra20actc	261	21	mAbs	mAbs	NNP
cord-329515-ra20actc	261	22	to	to	IN
cord-329515-ra20actc	261	23	a	a	DT
cord-329515-ra20actc	261	24	lumenal	lumenal	JJ
cord-329515-ra20actc	261	25	epitope	epitope	NN
cord-329515-ra20actc	261	26	of	of	IN
cord-329515-ra20actc	261	27	each	each	DT
cord-329515-ra20actc	261	28	protein	protein	NN
cord-329515-ra20actc	261	29	.	.	.
cord-329515-ra20actc	262	1	Nontransfected	nontransfected	JJ
cord-329515-ra20actc	262	2	control	control	NN
cord-329515-ra20actc	262	3	cells	cell	NNS
cord-329515-ra20actc	262	4	did	do	VBD
cord-329515-ra20actc	262	5	not	not	RB
cord-329515-ra20actc	262	6	react	react	VB
cord-329515-ra20actc	262	7	with	with	IN
cord-329515-ra20actc	262	8	the	the	DT
cord-329515-ra20actc	262	9	anti	anti	JJ
cord-329515-ra20actc	262	10	-	-	JJ
cord-329515-ra20actc	262	11	DPPIV	dppiv	JJ
cord-329515-ra20actc	262	12	mAb	mAb	NNS
cord-329515-ra20actc	262	13	(	(	-LRB-
cord-329515-ra20actc	262	14	data	datum	NNS
cord-329515-ra20actc	262	15	not	not	RB
cord-329515-ra20actc	262	16	shown	show	VBN
cord-329515-ra20actc	262	17	)	)	-RRB-
cord-329515-ra20actc	262	18	consistent	consistent	JJ
cord-329515-ra20actc	262	19	with	with	IN
cord-329515-ra20actc	262	20	evidence	evidence	NN
cord-329515-ra20actc	262	21	that	that	IN
cord-329515-ra20actc	262	22	COS	COS	NNP
cord-329515-ra20actc	262	23	cells	cell	NNS
cord-329515-ra20actc	262	24	have	have	VBP
cord-329515-ra20actc	262	25	tittle	tittle	NN
cord-329515-ra20actc	262	26	or	or	CC
cord-329515-ra20actc	262	27	no	no	DT
cord-329515-ra20actc	262	28	endogenous	endogenous	JJ
cord-329515-ra20actc	262	29	activity	activity	NN
cord-329515-ra20actc	262	30	of	of	IN
cord-329515-ra20actc	262	31	DPPIV	DPPIV	NNP
cord-329515-ra20actc	263	1	(	(	-LRB-
cord-329515-ra20actc	263	2	Ogata	Ogata	NNP
cord-329515-ra20actc	263	3	et	et	NNP
cord-329515-ra20actc	263	4	ai	ai	NNP
cord-329515-ra20actc	263	5	.	.	NNP
cord-329515-ra20actc	263	6	,	,	,
cord-329515-ra20actc	263	7	1992	1992	CD
cord-329515-ra20actc	263	8	)	)	-RRB-
cord-329515-ra20actc	263	9	.	.	.
cord-329515-ra20actc	264	1	As	as	IN
cord-329515-ra20actc	264	2	shown	show	VBN
cord-329515-ra20actc	264	3	in	in	IN
cord-329515-ra20actc	264	4	Fig	Fig	NNP
cord-329515-ra20actc	264	5	.	.	.
cord-329515-ra20actc	265	1	10	10	CD
cord-329515-ra20actc	265	2	,	,	,
cord-329515-ra20actc	265	3	a	a	DT
cord-329515-ra20actc	265	4	and	and	CC
cord-329515-ra20actc	265	5	b	b	NN
cord-329515-ra20actc	266	1	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	266	2	was	be	VBD
cord-329515-ra20actc	266	3	located	locate	VBN
cord-329515-ra20actc	266	4	on	on	IN
cord-329515-ra20actc	266	5	the	the	DT
cord-329515-ra20actc	266	6	cell	cell	NN
cord-329515-ra20actc	266	7	surface	surface	NN
cord-329515-ra20actc	266	8	as	as	IN
cord-329515-ra20actc	266	9	expected	expect	VBN
cord-329515-ra20actc	266	10	.	.	.
cord-329515-ra20actc	267	1	Bright	bright	JJ
cord-329515-ra20actc	267	2	cell	cell	NN
cord-329515-ra20actc	267	3	surface	surface	NN
cord-329515-ra20actc	267	4	staining	staining	NN
cord-329515-ra20actc	267	5	was	be	VBD
cord-329515-ra20actc	267	6	also	also	RB
cord-329515-ra20actc	267	7	observed	observe	VBN
cord-329515-ra20actc	267	8	for	for	IN
cord-329515-ra20actc	267	9	DPP	DPP	NNP
cord-329515-ra20actc	267	10	(	(	-LRB-
cord-329515-ra20actc	267	11	Fig	Fig	NNP
cord-329515-ra20actc	267	12	.	.	.
cord-329515-ra20actc	268	1	10	10	CD
cord-329515-ra20actc	268	2	d	d	NN
cord-329515-ra20actc	268	3	)	)	-RRB-
cord-329515-ra20actc	268	4	.	.	.
cord-329515-ra20actc	269	1	However	however	RB
cord-329515-ra20actc	269	2	,	,	,
cord-329515-ra20actc	269	3	unlike	unlike	IN
cord-329515-ra20actc	269	4	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	269	5	a	a	DT
cord-329515-ra20actc	269	6	portion	portion	NN
cord-329515-ra20actc	269	7	of	of	IN
cord-329515-ra20actc	269	8	DPP	DPP	NNP
cord-329515-ra20actc	269	9	was	be	VBD
cord-329515-ra20actc	269	10	also	also	RB
cord-329515-ra20actc	269	11	found	find	VBN
cord-329515-ra20actc	269	12	in	in	IN
cord-329515-ra20actc	269	13	the	the	DT
cord-329515-ra20actc	269	14	ER	ER	NNP
cord-329515-ra20actc	269	15	(	(	-LRB-
cord-329515-ra20actc	269	16	Fig	fig	NN
cord-329515-ra20actc	269	17	.	.	.
cord-329515-ra20actc	269	18	 	 	_SP
cord-329515-ra20actc	270	1	10	10	CD
cord-329515-ra20actc	270	2	c	c	NN
cord-329515-ra20actc	270	3	)	)	-RRB-
cord-329515-ra20actc	270	4	,	,	,
cord-329515-ra20actc	270	5	indicating	indicate	VBG
cord-329515-ra20actc	270	6	that	that	IN
cord-329515-ra20actc	270	7	the	the	DT
cord-329515-ra20actc	270	8	export	export	NN
cord-329515-ra20actc	270	9	of	of	IN
cord-329515-ra20actc	270	10	this	this	DT
cord-329515-ra20actc	270	11	chimeric	chimeric	JJ
cord-329515-ra20actc	270	12	protein	protein	NN
cord-329515-ra20actc	270	13	out	out	IN
cord-329515-ra20actc	270	14	of	of	IN
cord-329515-ra20actc	270	15	the	the	DT
cord-329515-ra20actc	270	16	ER	ER	NNP
cord-329515-ra20actc	270	17	is	be	VBZ
cord-329515-ra20actc	270	18	impaired	impair	VBN
cord-329515-ra20actc	270	19	to	to	IN
cord-329515-ra20actc	270	20	some	some	DT
cord-329515-ra20actc	270	21	extent	extent	NN
cord-329515-ra20actc	270	22	:	:	:
cord-329515-ra20actc	270	23	Very	very	RB
cord-329515-ra20actc	270	24	rarely	rarely	RB
cord-329515-ra20actc	270	25	a	a	DT
cord-329515-ra20actc	270	26	cell	cell	NN
cord-329515-ra20actc	270	27	showed	show	VBD
cord-329515-ra20actc	270	28	a	a	DT
cord-329515-ra20actc	270	29	p63wt	p63wt	CD
cord-329515-ra20actc	270	30	-	-	HYPH
cord-329515-ra20actc	270	31	related	relate	VBN
cord-329515-ra20actc	270	32	staining	staining	NN
cord-329515-ra20actc	270	33	pattern	pattern	NN
cord-329515-ra20actc	270	34	.	.	.
cord-329515-ra20actc	271	1	A	a	DT
cord-329515-ra20actc	271	2	similar	similar	JJ
cord-329515-ra20actc	271	3	result	result	NN
cord-329515-ra20actc	271	4	was	be	VBD
cord-329515-ra20actc	271	5	obtained	obtain	VBN
cord-329515-ra20actc	271	6	with	with	IN
cord-329515-ra20actc	271	7	a	a	DT
cord-329515-ra20actc	271	8	construct	construct	NN
cord-329515-ra20actc	271	9	that	that	WDT
cord-329515-ra20actc	271	10	only	only	RB
cord-329515-ra20actc	271	11	contained	contain	VBD
cord-329515-ra20actc	271	12	the	the	DT
cord-329515-ra20actc	271	13	lumenal	lumenal	JJ
cord-329515-ra20actc	271	14	domain	domain	NN
cord-329515-ra20actc	271	15	of	of	IN
cord-329515-ra20actc	271	16	p63	p63	NNP
cord-329515-ra20actc	271	17	(	(	-LRB-
cord-329515-ra20actc	271	18	DDP	DDP	NNP
cord-329515-ra20actc	271	19	;	;	:
cord-329515-ra20actc	271	20	DPPIV	DPPIV	NNP
cord-329515-ra20actc	271	21	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	271	22	;	;	:
cord-329515-ra20actc	271	23	DPPIV	DPPIV	NNP
cord-329515-ra20actc	271	24	transmembrane	transmembrane	NNP
cord-329515-ra20actc	271	25	,	,	,
cord-329515-ra20actc	271	26	p63	p63	NNP
cord-329515-ra20actc	271	27	lumenal	lumenal	NNP
cord-329515-ra20actc	271	28	;	;	:
cord-329515-ra20actc	271	29	Fig	Fig	NNP
cord-329515-ra20actc	271	30	.	.	.
cord-329515-ra20actc	271	31	9	9	CD
cord-329515-ra20actc	271	32	)	)	-RRB-
cord-329515-ra20actc	271	33	except	except	IN
cord-329515-ra20actc	271	34	that	that	IN
cord-329515-ra20actc	271	35	most	most	JJS
cord-329515-ra20actc	271	36	of	of	IN
cord-329515-ra20actc	271	37	the	the	DT
cord-329515-ra20actc	271	38	ER	ER	NNP
cord-329515-ra20actc	271	39	staining	staining	NN
cord-329515-ra20actc	271	40	was	be	VBD
cord-329515-ra20actc	271	41	now	now	RB
cord-329515-ra20actc	271	42	replaced	replace	VBN
cord-329515-ra20actc	271	43	by	by	IN
cord-329515-ra20actc	271	44	cell	cell	NN
cord-329515-ra20actc	271	45	surface	surface	NN
cord-329515-ra20actc	271	46	expression	expression	NN
cord-329515-ra20actc	271	47	(	(	-LRB-
cord-329515-ra20actc	271	48	data	datum	NNS
cord-329515-ra20actc	271	49	not	not	RB
cord-329515-ra20actc	271	50	shown	show	VBN
cord-329515-ra20actc	271	51	)	)	-RRB-
cord-329515-ra20actc	271	52	.	.	.
cord-329515-ra20actc	272	1	These	these	DT
cord-329515-ra20actc	272	2	results	result	NNS
cord-329515-ra20actc	272	3	confirm	confirm	VBP
cord-329515-ra20actc	272	4	that	that	IN
cord-329515-ra20actc	272	5	the	the	DT
cord-329515-ra20actc	272	6	p63	p63	CD
cord-329515-ra20actc	272	7	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	272	8	tail	tail	NN
cord-329515-ra20actc	272	9	is	be	VBZ
cord-329515-ra20actc	272	10	necessary	necessary	JJ
cord-329515-ra20actc	272	11	for	for	IN
cord-329515-ra20actc	272	12	proper	proper	JJ
cord-329515-ra20actc	272	13	localization	localization	NN
cord-329515-ra20actc	272	14	.	.	.
cord-329515-ra20actc	273	1	In	in	IN
cord-329515-ra20actc	273	2	the	the	DT
cord-329515-ra20actc	273	3	absence	absence	NN
cord-329515-ra20actc	273	4	of	of	IN
cord-329515-ra20actc	273	5	the	the	DT
cord-329515-ra20actc	273	6	p63	p63	CD
cord-329515-ra20actc	273	7	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	273	8	tail	tail	NN
cord-329515-ra20actc	273	9	,	,	,
cord-329515-ra20actc	273	10	the	the	DT
cord-329515-ra20actc	273	11	lumenal	lumenal	NNP
cord-329515-ra20actc	273	12	p63	p63	NNP
cord-329515-ra20actc	273	13	domain	domain	NN
cord-329515-ra20actc	273	14	alone	alone	RB
cord-329515-ra20actc	273	15	or	or	CC
cord-329515-ra20actc	273	16	in	in	IN
cord-329515-ra20actc	273	17	combination	combination	NN
cord-329515-ra20actc	273	18	with	with	IN
cord-329515-ra20actc	273	19	its	-PRON-	PRP$
cord-329515-ra20actc	273	20	transmembrane	transmembrane	NN
cord-329515-ra20actc	273	21	domain	domain	NN
cord-329515-ra20actc	273	22	is	be	VBZ
cord-329515-ra20actc	273	23	not	not	RB
cord-329515-ra20actc	273	24	sufficient	sufficient	JJ
cord-329515-ra20actc	273	25	to	to	TO
cord-329515-ra20actc	273	26	achieve	achieve	VB
cord-329515-ra20actc	273	27	retention	retention	NN
cord-329515-ra20actc	273	28	.	.	.
cord-329515-ra20actc	274	1	We	-PRON-	PRP
cord-329515-ra20actc	274	2	next	next	RB
cord-329515-ra20actc	274	3	asked	ask	VBD
cord-329515-ra20actc	274	4	whether	whether	IN
cord-329515-ra20actc	274	5	the	the	DT
cord-329515-ra20actc	274	6	lumenal	lumenal	JJ
cord-329515-ra20actc	274	7	domain	domain	NN
cord-329515-ra20actc	274	8	of	of	IN
cord-329515-ra20actc	274	9	p63	p63	CD
cord-329515-ra20actc	274	10	is	be	VBZ
cord-329515-ra20actc	274	11	dispensable	dispensable	JJ
cord-329515-ra20actc	274	12	for	for	IN
cord-329515-ra20actc	274	13	the	the	DT
cord-329515-ra20actc	274	14	correct	correct	JJ
cord-329515-ra20actc	274	15	targeting	targeting	NN
cord-329515-ra20actc	274	16	of	of	IN
cord-329515-ra20actc	274	17	the	the	DT
cord-329515-ra20actc	274	18	protein	protein	NN
cord-329515-ra20actc	274	19	.	.	.
cord-329515-ra20actc	275	1	To	to	IN
cord-329515-ra20actc	275	2	this	this	DT
cord-329515-ra20actc	275	3	end	end	NN
cord-329515-ra20actc	275	4	,	,	,
cord-329515-ra20actc	275	5	a	a	DT
cord-329515-ra20actc	275	6	chimeric	chimeric	JJ
cord-329515-ra20actc	275	7	construct	construct	NN
cord-329515-ra20actc	275	8	in	in	IN
cord-329515-ra20actc	275	9	which	which	WDT
cord-329515-ra20actc	275	10	the	the	DT
cord-329515-ra20actc	275	11	lumenal	lumenal	JJ
cord-329515-ra20actc	275	12	domain	domain	NN
cord-329515-ra20actc	275	13	of	of	IN
cord-329515-ra20actc	275	14	p63	p63	CD
cord-329515-ra20actc	275	15	was	be	VBD
cord-329515-ra20actc	275	16	replaced	replace	VBN
cord-329515-ra20actc	275	17	by	by	IN
cord-329515-ra20actc	275	18	that	that	DT
cord-329515-ra20actc	275	19	of	of	IN
cord-329515-ra20actc	275	20	DPPIV	DPPIV	NNP
cord-329515-ra20actc	276	1	(	(	-LRB-
cord-329515-ra20actc	276	2	PPD	PPD	NNP
cord-329515-ra20actc	276	3	,	,	,
cord-329515-ra20actc	276	4	p63	p63	CD
cord-329515-ra20actc	276	5	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	276	6	,	,	,
cord-329515-ra20actc	276	7	p63	p63	NN
cord-329515-ra20actc	276	8	transmembrane	transmembrane	NN
cord-329515-ra20actc	276	9	,	,	,
cord-329515-ra20actc	276	10	DPPIV	DPPIV	NNP
cord-329515-ra20actc	276	11	lumenal	lumenal	NNP
cord-329515-ra20actc	276	12	;	;	:
cord-329515-ra20actc	276	13	Fig	Fig	NNP
cord-329515-ra20actc	276	14	.	.	.
cord-329515-ra20actc	276	15	9	9	CD
cord-329515-ra20actc	276	16	)	)	-RRB-
cord-329515-ra20actc	276	17	was	be	VBD
cord-329515-ra20actc	276	18	created	create	VBN
cord-329515-ra20actc	276	19	.	.	.
cord-329515-ra20actc	277	1	In	in	IN
cord-329515-ra20actc	277	2	a	a	DT
cord-329515-ra20actc	277	3	related	related	JJ
cord-329515-ra20actc	277	4	construct	construct	NN
cord-329515-ra20actc	277	5	we	-PRON-	PRP
cord-329515-ra20actc	277	6	linked	link	VBD
cord-329515-ra20actc	277	7	the	the	DT
cord-329515-ra20actc	277	8	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	277	9	and	and	CC
cord-329515-ra20actc	277	10	transmembrane	transmembrane	JJ
cord-329515-ra20actc	277	11	domains	domain	NNS
cord-329515-ra20actc	277	12	of	of	IN
cord-329515-ra20actc	277	13	A24	A24	NNP
cord-329515-ra20actc	277	14	-	-	HYPH
cord-329515-ra20actc	277	15	101	101	CD
cord-329515-ra20actc	277	16	to	to	IN
cord-329515-ra20actc	277	17	the	the	DT
cord-329515-ra20actc	277	18	DPPIV	DPPIV	NNP
cord-329515-ra20actc	277	19	lumenal	lumenal	JJ
cord-329515-ra20actc	277	20	domain	domain	NN
cord-329515-ra20actc	277	21	(	(	-LRB-
cord-329515-ra20actc	277	22	A24	A24	NNP
cord-329515-ra20actc	277	23	-	-	HYPH
cord-329515-ra20actc	277	24	101PPD	101PPD	NNP
cord-329515-ra20actc	277	25	,	,	,
cord-329515-ra20actc	278	1	p63	p63	NNP
cord-329515-ra20actc	278	2	with	with	IN
cord-329515-ra20actc	278	3	deletion	deletion	NN
cord-329515-ra20actc	278	4	of	of	IN
cord-329515-ra20actc	278	5	amino	amino	JJ
cord-329515-ra20actc	278	6	acids	acid	NNS
cord-329515-ra20actc	278	7	24	24	CD
cord-329515-ra20actc	278	8	-	-	SYM
cord-329515-ra20actc	278	9	101	101	CD
cord-329515-ra20actc	278	10	cyto-	cyto-	NN
cord-329515-ra20actc	278	11	plasmic	plasmic	JJ
cord-329515-ra20actc	278	12	,	,	,
cord-329515-ra20actc	278	13	p63	p63	JJ
cord-329515-ra20actc	278	14	transmembrane	transmembrane	NN
cord-329515-ra20actc	278	15	,	,	,
cord-329515-ra20actc	278	16	DPPIV	DPPIV	NNP
cord-329515-ra20actc	278	17	lumenal	lumenal	NNP
cord-329515-ra20actc	278	18	;	;	:
cord-329515-ra20actc	278	19	Fig	Fig	NNP
cord-329515-ra20actc	278	20	.	.	.
cord-329515-ra20actc	278	21	9	9	CD
cord-329515-ra20actc	278	22	)	)	-RRB-
cord-329515-ra20actc	278	23	.	.	.
cord-329515-ra20actc	279	1	When	when	WRB
cord-329515-ra20actc	279	2	the	the	DT
cord-329515-ra20actc	279	3	subeellular	subeellular	NNP
cord-329515-ra20actc	279	4	localization	localization	NN
cord-329515-ra20actc	279	5	of	of	IN
cord-329515-ra20actc	279	6	the	the	DT
cord-329515-ra20actc	279	7	chimeric	chimeric	JJ
cord-329515-ra20actc	279	8	proteins	protein	NNS
cord-329515-ra20actc	279	9	was	be	VBD
cord-329515-ra20actc	279	10	analyzed	analyze	VBN
cord-329515-ra20actc	279	11	in	in	IN
cord-329515-ra20actc	279	12	transfected	transfecte	VBN
cord-329515-ra20actc	279	13	COS	cos	NN
cord-329515-ra20actc	279	14	cells	cell	NNS
cord-329515-ra20actc	279	15	,	,	,
cord-329515-ra20actc	279	16	A24	A24	NNP
cord-329515-ra20actc	279	17	-	-	HYPH
cord-329515-ra20actc	279	18	101PPD	101PPD	NNP
cord-329515-ra20actc	279	19	showed	show	VBD
cord-329515-ra20actc	279	20	the	the	DT
cord-329515-ra20actc	279	21	same	same	JJ
cord-329515-ra20actc	279	22	distribution	distribution	NN
cord-329515-ra20actc	279	23	as	as	IN
cord-329515-ra20actc	279	24	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	279	25	.	.	.
cord-329515-ra20actc	280	1	There	there	EX
cord-329515-ra20actc	280	2	was	be	VBD
cord-329515-ra20actc	280	3	strong	strong	JJ
cord-329515-ra20actc	280	4	labeling	labeling	NN
cord-329515-ra20actc	280	5	of	of	IN
cord-329515-ra20actc	280	6	the	the	DT
cord-329515-ra20actc	280	7	cell	cell	NN
cord-329515-ra20actc	280	8	surface	surface	NN
cord-329515-ra20actc	280	9	(	(	-LRB-
cord-329515-ra20actc	280	10	Fig	Fig	NNP
cord-329515-ra20actc	280	11	.	.	.
cord-329515-ra20actc	280	12	10	10	CD
cord-329515-ra20actc	280	13	f	f	NNP
cord-329515-ra20actc	280	14	)	)	-RRB-
cord-329515-ra20actc	280	15	,	,	,
cord-329515-ra20actc	280	16	but	but	CC
cord-329515-ra20actc	280	17	no	no	DT
cord-329515-ra20actc	280	18	internal	internal	JJ
cord-329515-ra20actc	280	19	staining	staining	NN
cord-329515-ra20actc	280	20	with	with	IN
cord-329515-ra20actc	280	21	a	a	DT
cord-329515-ra20actc	280	22	p63wt	p63wt	CD
cord-329515-ra20actc	280	23	pattern	pattern	NN
cord-329515-ra20actc	280	24	(	(	-LRB-
cord-329515-ra20actc	280	25	Fig	Fig	NNP
cord-329515-ra20actc	280	26	.	.	.
cord-329515-ra20actc	280	27	10	10	CD
cord-329515-ra20actc	280	28	e	e	NN
cord-329515-ra20actc	280	29	)	)	-RRB-
cord-329515-ra20actc	280	30	.	.	.
cord-329515-ra20actc	281	1	The	the	DT
cord-329515-ra20actc	281	2	same	same	JJ
cord-329515-ra20actc	281	3	was	be	VBD
cord-329515-ra20actc	281	4	true	true	JJ
cord-329515-ra20actc	281	5	for	for	IN
cord-329515-ra20actc	281	6	the	the	DT
cord-329515-ra20actc	281	7	PPD	PPD	NNP
cord-329515-ra20actc	281	8	chimera	chimera	NN
cord-329515-ra20actc	281	9	(	(	-LRB-
cord-329515-ra20actc	281	10	Fig	Fig	NNP
cord-329515-ra20actc	281	11	.	.	NNP
cord-329515-ra20actc	281	12	10	10	CD
cord-329515-ra20actc	281	13	,	,	,
cord-329515-ra20actc	281	14	g	g	NN
cord-329515-ra20actc	281	15	and	and	CC
cord-329515-ra20actc	281	16	h	h	NNP
cord-329515-ra20actc	281	17	)	)	-RRB-
cord-329515-ra20actc	281	18	except	except	IN
cord-329515-ra20actc	281	19	that	that	IN
cord-329515-ra20actc	281	20	the	the	DT
cord-329515-ra20actc	281	21	internal	internal	JJ
cord-329515-ra20actc	281	22	staining	staining	NN
cord-329515-ra20actc	281	23	pattern	pattern	NN
cord-329515-ra20actc	281	24	included	include	VBD
cord-329515-ra20actc	281	25	more	more	JJR
cord-329515-ra20actc	281	26	ER	er	NN
cord-329515-ra20actc	281	27	staining	staining	NN
cord-329515-ra20actc	281	28	in	in	IN
cord-329515-ra20actc	281	29	addition	addition	NN
cord-329515-ra20actc	281	30	to	to	IN
cord-329515-ra20actc	281	31	the	the	DT
cord-329515-ra20actc	281	32	Golgi	Golgi	NNP
cord-329515-ra20actc	281	33	and	and	CC
cord-329515-ra20actc	281	34	cell	cell	NN
cord-329515-ra20actc	281	35	surface	surface	NN
cord-329515-ra20actc	281	36	staining	stain	VBG
cord-329515-ra20actc	281	37	predominantly	predominantly	RB
cord-329515-ra20actc	281	38	found	find	VBN
cord-329515-ra20actc	281	39	for	for	IN
cord-329515-ra20actc	281	40	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	281	41	and	and	CC
cord-329515-ra20actc	281	42	A24	A24	NNP
cord-329515-ra20actc	281	43	-	-	HYPH
cord-329515-ra20actc	281	44	101PPD	101PPD	NNP
cord-329515-ra20actc	281	45	.	.	.
cord-329515-ra20actc	282	1	These	these	DT
cord-329515-ra20actc	282	2	data	datum	NNS
cord-329515-ra20actc	282	3	demonstrate	demonstrate	VBP
cord-329515-ra20actc	282	4	that	that	IN
cord-329515-ra20actc	282	5	the	the	DT
cord-329515-ra20actc	282	6	presence	presence	NN
cord-329515-ra20actc	282	7	of	of	IN
cord-329515-ra20actc	282	8	the	the	DT
cord-329515-ra20actc	282	9	lumenal	lumenal	JJ
cord-329515-ra20actc	282	10	domain	domain	NN
cord-329515-ra20actc	282	11	of	of	IN
cord-329515-ra20actc	282	12	the	the	DT
cord-329515-ra20actc	282	13	p63	p63	CD
cord-329515-ra20actc	282	14	molecule	molecule	NN
cord-329515-ra20actc	282	15	is	be	VBZ
cord-329515-ra20actc	282	16	essential	essential	JJ
cord-329515-ra20actc	282	17	for	for	IN
cord-329515-ra20actc	282	18	the	the	DT
cord-329515-ra20actc	282	19	correct	correct	JJ
cord-329515-ra20actc	282	20	localization	localization	NN
cord-329515-ra20actc	282	21	of	of	IN
cord-329515-ra20actc	282	22	the	the	DT
cord-329515-ra20actc	282	23	protein	protein	NN
cord-329515-ra20actc	282	24	.	.	.
cord-329515-ra20actc	283	1	The	the	DT
cord-329515-ra20actc	283	2	results	result	NNS
cord-329515-ra20actc	283	3	with	with	IN
cord-329515-ra20actc	283	4	the	the	DT
cord-329515-ra20actc	283	5	PPD	PPD	NNP
cord-329515-ra20actc	283	6	and	and	CC
cord-329515-ra20actc	283	7	A24	A24	NNP
cord-329515-ra20actc	283	8	-	-	HYPH
cord-329515-ra20actc	283	9	101PPD	101PPD	NNP
cord-329515-ra20actc	283	10	constructs	construct	VBZ
cord-329515-ra20actc	283	11	together	together	RB
cord-329515-ra20actc	283	12	with	with	IN
cord-329515-ra20actc	283	13	the	the	DT
cord-329515-ra20actc	283	14	mutational	mutational	JJ
cord-329515-ra20actc	283	15	analysis	analysis	NN
cord-329515-ra20actc	283	16	of	of	IN
cord-329515-ra20actc	283	17	the	the	DT
cord-329515-ra20actc	283	18	p63	p63	CD
cord-329515-ra20actc	283	19	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	283	20	tail	tail	NN
cord-329515-ra20actc	284	1	establish	establish	VB
cord-329515-ra20actc	284	2	that	that	IN
cord-329515-ra20actc	284	3	the	the	DT
cord-329515-ra20actc	284	4	transmembrane	transmembrane	NN
cord-329515-ra20actc	284	5	domain	domain	NN
cord-329515-ra20actc	284	6	of	of	IN
cord-329515-ra20actc	284	7	p63	p63	CD
cord-329515-ra20actc	284	8	is	be	VBZ
cord-329515-ra20actc	284	9	not	not	RB
cord-329515-ra20actc	284	10	sufficient	sufficient	JJ
cord-329515-ra20actc	284	11	for	for	IN
cord-329515-ra20actc	284	12	its	-PRON-	PRP$
cord-329515-ra20actc	284	13	localization	localization	NN
cord-329515-ra20actc	284	14	.	.	.
cord-329515-ra20actc	285	1	To	to	TO
cord-329515-ra20actc	285	2	determine	determine	VB
cord-329515-ra20actc	285	3	whether	whether	IN
cord-329515-ra20actc	285	4	this	this	DT
cord-329515-ra20actc	285	5	domain	domain	NN
cord-329515-ra20actc	285	6	is	be	VBZ
cord-329515-ra20actc	285	7	a	a	DT
cord-329515-ra20actc	285	8	necessary	necessary	JJ
cord-329515-ra20actc	285	9	component	component	NN
cord-329515-ra20actc	285	10	,	,	,
cord-329515-ra20actc	285	11	we	-PRON-	PRP
cord-329515-ra20actc	285	12	created	create	VBD
cord-329515-ra20actc	285	13	an	an	DT
cord-329515-ra20actc	285	14	additional	additional	JJ
cord-329515-ra20actc	285	15	chimera	chimera	NN
cord-329515-ra20actc	285	16	that	that	WDT
cord-329515-ra20actc	285	17	combines	combine	VBZ
cord-329515-ra20actc	285	18	a	a	DT
cord-329515-ra20actc	285	19	p63	p63	CD
cord-329515-ra20actc	285	20	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	285	21	tall	tall	JJ
cord-329515-ra20actc	285	22	that	that	WDT
cord-329515-ra20actc	285	23	has	have	VBZ
cord-329515-ra20actc	285	24	amino	amino	JJ
cord-329515-ra20actc	285	25	acids	acid	NNS
cord-329515-ra20actc	286	1	24	24	CD
cord-329515-ra20actc	286	2	-	-	SYM
cord-329515-ra20actc	286	3	101	101	CD
cord-329515-ra20actc	286	4	deleted	delete	VBD
cord-329515-ra20actc	286	5	with	with	IN
cord-329515-ra20actc	286	6	the	the	DT
cord-329515-ra20actc	286	7	transmembrane	transmembrane	NN
cord-329515-ra20actc	286	8	domain	domain	NN
cord-329515-ra20actc	286	9	of	of	IN
cord-329515-ra20actc	286	10	DPPIV	DPPIV	NNP
cord-329515-ra20actc	286	11	and	and	CC
cord-329515-ra20actc	286	12	the	the	DT
cord-329515-ra20actc	286	13	lumenal	lumenal	JJ
cord-329515-ra20actc	286	14	part	part	NN
cord-329515-ra20actc	286	15	of	of	IN
cord-329515-ra20actc	286	16	p63	p63	CD
cord-329515-ra20actc	286	17	(	(	-LRB-
cord-329515-ra20actc	286	18	A24	A24	NNP
cord-329515-ra20actc	286	19	-	-	HYPH
cord-329515-ra20actc	286	20	101PDP	101pdp	JJ
cord-329515-ra20actc	286	21	;	;	:
cord-329515-ra20actc	286	22	p63	p63	CD
cord-329515-ra20actc	286	23	with	with	IN
cord-329515-ra20actc	286	24	deletion	deletion	NN
cord-329515-ra20actc	286	25	of	of	IN
cord-329515-ra20actc	286	26	amino	amino	JJ
cord-329515-ra20actc	286	27	acids	acid	NNS
cord-329515-ra20actc	286	28	24	24	CD
cord-329515-ra20actc	286	29	-	-	SYM
cord-329515-ra20actc	286	30	101	101	CD
cord-329515-ra20actc	286	31	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	286	32	,	,	,
cord-329515-ra20actc	286	33	DPPIV	DPPIV	NNP
cord-329515-ra20actc	286	34	transmembrane	transmembrane	NNP
cord-329515-ra20actc	286	35	,	,	,
cord-329515-ra20actc	286	36	p63	p63	NNP
cord-329515-ra20actc	286	37	lumenal	lumenal	NNP
cord-329515-ra20actc	286	38	;	;	:
cord-329515-ra20actc	286	39	Fig	Fig	NNP
cord-329515-ra20actc	286	40	.	.	.
cord-329515-ra20actc	286	41	9	9	CD
cord-329515-ra20actc	286	42	)	)	-RRB-
cord-329515-ra20actc	286	43	.	.	.
cord-329515-ra20actc	287	1	Immunofluorescence	immunofluorescence	NN
cord-329515-ra20actc	287	2	microscopy	microscopy	NN
cord-329515-ra20actc	287	3	of	of	IN
cord-329515-ra20actc	287	4	transfected	transfecte	VBN
cord-329515-ra20actc	287	5	cells	cell	NNS
cord-329515-ra20actc	287	6	showed	show	VBD
cord-329515-ra20actc	287	7	that	that	IN
cord-329515-ra20actc	287	8	the	the	DT
cord-329515-ra20actc	287	9	internal	internal	JJ
cord-329515-ra20actc	287	10	distribution	distribution	NN
cord-329515-ra20actc	287	11	of	of	IN
cord-329515-ra20actc	287	12	A24	A24	NNP
cord-329515-ra20actc	287	13	-	-	HYPH
cord-329515-ra20actc	287	14	101PDP	101PDP	NNP
cord-329515-ra20actc	287	15	is	be	VBZ
cord-329515-ra20actc	287	16	very	very	RB
cord-329515-ra20actc	287	17	similar	similar	JJ
cord-329515-ra20actc	287	18	to	to	IN
cord-329515-ra20actc	287	19	p63wt	p63wt	CD
cord-329515-ra20actc	288	1	(	(	-LRB-
cord-329515-ra20actc	288	2	Fig	Fig	NNP
cord-329515-ra20actc	288	3	.	.	.
cord-329515-ra20actc	288	4	10	10	CD
cord-329515-ra20actc	288	5	i	i	NN
cord-329515-ra20actc	288	6	)	)	-RRB-
cord-329515-ra20actc	288	7	.	.	.
cord-329515-ra20actc	289	1	Unlike	unlike	IN
cord-329515-ra20actc	289	2	p63wt	p63wt	NNP
cord-329515-ra20actc	289	3	,	,	,
cord-329515-ra20actc	289	4	however	however	RB
cord-329515-ra20actc	289	5	,	,	,
cord-329515-ra20actc	289	6	some	some	DT
cord-329515-ra20actc	289	7	A24	A24	NNP
cord-329515-ra20actc	289	8	-	-	HYPH
cord-329515-ra20actc	289	9	101PDP	101pdp	JJ
cord-329515-ra20actc	289	10	molecules	molecule	NNS
cord-329515-ra20actc	289	11	were	be	VBD
cord-329515-ra20actc	289	12	detected	detect	VBN
cord-329515-ra20actc	289	13	on	on	IN
cord-329515-ra20actc	289	14	the	the	DT
cord-329515-ra20actc	289	15	plasma	plasma	NN
cord-329515-ra20actc	289	16	membrane	membrane	NN
cord-329515-ra20actc	289	17	in	in	IN
cord-329515-ra20actc	289	18	unpermeabilized	unpermeabilized	JJ
cord-329515-ra20actc	289	19	cells	cell	NNS
cord-329515-ra20actc	289	20	(	(	-LRB-
cord-329515-ra20actc	289	21	Fig	Fig	NNP
cord-329515-ra20actc	289	22	.	.	.
cord-329515-ra20actc	289	23	10	10	CD
cord-329515-ra20actc	289	24	j	j	NNP
cord-329515-ra20actc	289	25	)	)	-RRB-
cord-329515-ra20actc	289	26	.	.	.
cord-329515-ra20actc	290	1	The	the	DT
cord-329515-ra20actc	290	2	intensity	intensity	NN
cord-329515-ra20actc	290	3	of	of	IN
cord-329515-ra20actc	290	4	this	this	DT
cord-329515-ra20actc	290	5	cell	cell	NN
cord-329515-ra20actc	290	6	surface	surface	NN
cord-329515-ra20actc	290	7	staining	staining	NN
cord-329515-ra20actc	290	8	was	be	VBD
cord-329515-ra20actc	290	9	fainter	faint	JJR
cord-329515-ra20actc	290	10	than	than	IN
cord-329515-ra20actc	290	11	that	that	DT
cord-329515-ra20actc	290	12	of	of	IN
cord-329515-ra20actc	290	13	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	290	14	or	or	CC
cord-329515-ra20actc	290	15	any	any	DT
cord-329515-ra20actc	290	16	of	of	IN
cord-329515-ra20actc	290	17	the	the	DT
cord-329515-ra20actc	290	18	other	other	JJ
cord-329515-ra20actc	290	19	chimeric	chimeric	JJ
cord-329515-ra20actc	290	20	constructs	construct	NNS
cord-329515-ra20actc	290	21	.	.	.
cord-329515-ra20actc	291	1	Thus	thus	RB
cord-329515-ra20actc	291	2	,	,	,
cord-329515-ra20actc	291	3	while	while	IN
cord-329515-ra20actc	291	4	the	the	DT
cord-329515-ra20actc	291	5	transmembrane	transmembrane	NN
cord-329515-ra20actc	291	6	domain	domain	NN
cord-329515-ra20actc	291	7	contributes	contribute	VBZ
cord-329515-ra20actc	291	8	to	to	IN
cord-329515-ra20actc	291	9	the	the	DT
cord-329515-ra20actc	291	10	complete	complete	JJ
cord-329515-ra20actc	291	11	intracellular	intracellular	JJ
cord-329515-ra20actc	291	12	retention	retention	NN
cord-329515-ra20actc	291	13	of	of	IN
cord-329515-ra20actc	291	14	p63	p63	CD
cord-329515-ra20actc	291	15	,	,	,
cord-329515-ra20actc	291	16	it	-PRON-	PRP
cord-329515-ra20actc	291	17	appears	appear	VBZ
cord-329515-ra20actc	291	18	to	to	TO
cord-329515-ra20actc	291	19	be	be	VB
cord-329515-ra20actc	291	20	less	less	RBR
cord-329515-ra20actc	291	21	important	important	JJ
cord-329515-ra20actc	291	22	for	for	IN
cord-329515-ra20actc	291	23	the	the	DT
cord-329515-ra20actc	291	24	overall	overall	JJ
cord-329515-ra20actc	291	25	localization	localization	NN
cord-329515-ra20actc	291	26	than	than	IN
cord-329515-ra20actc	291	27	its	-PRON-	PRP$
cord-329515-ra20actc	291	28	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	291	29	and	and	CC
cord-329515-ra20actc	291	30	lumenal	lumenal	JJ
cord-329515-ra20actc	291	31	counterparts	counterpart	NNS
cord-329515-ra20actc	291	32	.	.	.
cord-329515-ra20actc	292	1	The	the	DT
cord-329515-ra20actc	292	2	retention	retention	NN
cord-329515-ra20actc	292	3	behavior	behavior	NN
cord-329515-ra20actc	292	4	of	of	IN
cord-329515-ra20actc	292	5	p63	p63	CD
cord-329515-ra20actc	292	6	described	describe	VBN
cord-329515-ra20actc	292	7	so	so	RB
cord-329515-ra20actc	292	8	far	far	RB
cord-329515-ra20actc	292	9	suggested	suggest	VBN
cord-329515-ra20actc	292	10	that	that	IN
cord-329515-ra20actc	292	11	the	the	DT
cord-329515-ra20actc	292	12	underlying	underlying	JJ
cord-329515-ra20actc	292	13	molecular	molecular	JJ
cord-329515-ra20actc	292	14	mechanism	mechanism	NN
cord-329515-ra20actc	292	15	might	may	MD
cord-329515-ra20actc	292	16	be	be	VB
cord-329515-ra20actc	292	17	related	relate	VBN
cord-329515-ra20actc	292	18	to	to	IN
cord-329515-ra20actc	292	19	physical	physical	JJ
cord-329515-ra20actc	292	20	properties	property	NNS
cord-329515-ra20actc	292	21	within	within	IN
cord-329515-ra20actc	292	22	the	the	DT
cord-329515-ra20actc	292	23	p63	p63	NNP
cord-329515-ra20actc	292	24	protein	protein	NN
cord-329515-ra20actc	292	25	itself	-PRON-	PRP
cord-329515-ra20actc	292	26	.	.	.
cord-329515-ra20actc	293	1	Two	two	CD
cord-329515-ra20actc	293	2	findings	finding	NNS
cord-329515-ra20actc	293	3	in	in	IN
cord-329515-ra20actc	293	4	particular	particular	JJ
cord-329515-ra20actc	293	5	supported	support	VBD
cord-329515-ra20actc	293	6	this	this	DT
cord-329515-ra20actc	293	7	idea	idea	NN
cord-329515-ra20actc	293	8	.	.	.
cord-329515-ra20actc	294	1	First	first	RB
cord-329515-ra20actc	294	2	,	,	,
cord-329515-ra20actc	294	3	overexpression	overexpression	NN
cord-329515-ra20actc	294	4	of	of	IN
cord-329515-ra20actc	294	5	p63	p63	NN
cord-329515-ra20actc	294	6	did	do	VBD
cord-329515-ra20actc	294	7	not	not	RB
cord-329515-ra20actc	294	8	saturate	saturate	VB
cord-329515-ra20actc	294	9	the	the	DT
cord-329515-ra20actc	294	10	retention	retention	NN
cord-329515-ra20actc	294	11	mechanism	mechanism	NN
cord-329515-ra20actc	294	12	.	.	.
cord-329515-ra20actc	295	1	And	and	CC
cord-329515-ra20actc	295	2	second	second	RB
cord-329515-ra20actc	295	3	,	,	,
cord-329515-ra20actc	295	4	the	the	DT
cord-329515-ra20actc	295	5	p63	p63	CD
cord-329515-ra20actc	295	6	localization	localization	NN
cord-329515-ra20actc	295	7	could	could	MD
cord-329515-ra20actc	295	8	not	not	RB
cord-329515-ra20actc	295	9	be	be	VB
cord-329515-ra20actc	295	10	transferred	transfer	VBN
cord-329515-ra20actc	295	11	to	to	IN
cord-329515-ra20actc	295	12	another	another	DT
cord-329515-ra20actc	295	13	protein	protein	NN
cord-329515-ra20actc	295	14	.	.	.
cord-329515-ra20actc	296	1	We	-PRON-	PRP
cord-329515-ra20actc	296	2	therefore	therefore	RB
cord-329515-ra20actc	296	3	speculated	speculate	VBD
cord-329515-ra20actc	296	4	that	that	IN
cord-329515-ra20actc	296	5	individual	individual	JJ
cord-329515-ra20actc	296	6	1363	1363	CD
cord-329515-ra20actc	296	7	molecules	molecule	NNS
cord-329515-ra20actc	296	8	might	may	MD
cord-329515-ra20actc	296	9	interact	interact	VB
cord-329515-ra20actc	296	10	with	with	IN
cord-329515-ra20actc	296	11	each	each	DT
cord-329515-ra20actc	296	12	other	other	JJ
cord-329515-ra20actc	296	13	to	to	TO
cord-329515-ra20actc	296	14	form	form	VB
cord-329515-ra20actc	296	15	higher	high	JJR
cord-329515-ra20actc	296	16	order	order	NN
cord-329515-ra20actc	296	17	structures	structure	NNS
cord-329515-ra20actc	296	18	.	.	.
cord-329515-ra20actc	297	1	To	to	TO
cord-329515-ra20actc	297	2	test	test	VB
cord-329515-ra20actc	297	3	this	this	DT
cord-329515-ra20actc	297	4	hypothesis	hypothesis	NN
cord-329515-ra20actc	297	5	p63wt	p63wt	NNP
cord-329515-ra20actc	297	6	was	be	VBD
cord-329515-ra20actc	297	7	analyzed	analyze	VBN
cord-329515-ra20actc	297	8	by	by	IN
cord-329515-ra20actc	297	9	centrifugation	centrifugation	NN
cord-329515-ra20actc	297	10	.	.	.
cord-329515-ra20actc	298	1	In	in	IN
cord-329515-ra20actc	298	2	this	this	DT
cord-329515-ra20actc	298	3	experiment	experiment	NN
cord-329515-ra20actc	298	4	COS	cos	NN
cord-329515-ra20actc	298	5	cells	cell	NNS
cord-329515-ra20actc	298	6	transfected	transfecte	VBN
cord-329515-ra20actc	298	7	with	with	IN
cord-329515-ra20actc	298	8	p63wt	p63wt	NNP
cord-329515-ra20actc	298	9	were	be	VBD
cord-329515-ra20actc	298	10	solubilized	solubilize	VBN
cord-329515-ra20actc	298	11	with	with	IN
cord-329515-ra20actc	298	12	Triton	Triton	NNP
cord-329515-ra20actc	298	13	X-100	x-100	RB
cord-329515-ra20actc	298	14	at	at	IN
cord-329515-ra20actc	298	15	different	different	JJ
cord-329515-ra20actc	298	16	pHs	pHs	NNP
cord-329515-ra20actc	298	17	(	(	-LRB-
cord-329515-ra20actc	298	18	5.8	5.8	CD
cord-329515-ra20actc	298	19	,	,	,
cord-329515-ra20actc	298	20	6.3	6.3	CD
cord-329515-ra20actc	298	21	,	,	,
cord-329515-ra20actc	298	22	6.8	6.8	CD
cord-329515-ra20actc	298	23	,	,	,
cord-329515-ra20actc	298	24	7.4	7.4	CD
cord-329515-ra20actc	298	25	,	,	,
cord-329515-ra20actc	298	26	and	and	CC
cord-329515-ra20actc	298	27	8.0	8.0	CD
cord-329515-ra20actc	298	28	)	)	-RRB-
cord-329515-ra20actc	298	29	and	and	CC
cord-329515-ra20actc	298	30	then	then	RB
cord-329515-ra20actc	298	31	subjected	subject	VBN
cord-329515-ra20actc	298	32	to	to	IN
cord-329515-ra20actc	298	33	centrifugation	centrifugation	NN
cord-329515-ra20actc	298	34	at	at	IN
cord-329515-ra20actc	298	35	100,000	100,000	CD
cord-329515-ra20actc	298	36	g	g	NN
cord-329515-ra20actc	298	37	for	for	IN
cord-329515-ra20actc	298	38	1	1	CD
cord-329515-ra20actc	298	39	h.	h.	NN
cord-329515-ra20actc	299	1	The	the	DT
cord-329515-ra20actc	299	2	resulting	result	VBG
cord-329515-ra20actc	299	3	supernatant	supernatant	NN
cord-329515-ra20actc	299	4	and	and	CC
cord-329515-ra20actc	299	5	pellet	pellet	NN
cord-329515-ra20actc	299	6	fractions	fraction	NNS
cord-329515-ra20actc	299	7	were	be	VBD
cord-329515-ra20actc	299	8	then	then	RB
cord-329515-ra20actc	299	9	assayed	assay	VBN
cord-329515-ra20actc	299	10	for	for	IN
cord-329515-ra20actc	299	11	the	the	DT
cord-329515-ra20actc	299	12	presence	presence	NN
cord-329515-ra20actc	299	13	of	of	IN
cord-329515-ra20actc	299	14	p63	p63	CD
cord-329515-ra20actc	299	15	by	by	IN
cord-329515-ra20actc	299	16	SDS	SDS	NNP
cord-329515-ra20actc	299	17	-	-	HYPH
cord-329515-ra20actc	299	18	PAGE	PAGE	NNP
cord-329515-ra20actc	299	19	and	and	CC
cord-329515-ra20actc	299	20	immunoblotting	immunoblotte	VBG
cord-329515-ra20actc	299	21	with	with	IN
cord-329515-ra20actc	299	22	an	an	DT
cord-329515-ra20actc	299	23	anti	anti	JJ
cord-329515-ra20actc	299	24	-	-	JJ
cord-329515-ra20actc	299	25	p63	p63	JJ
cord-329515-ra20actc	299	26	mAb	mAb	NNS
cord-329515-ra20actc	299	27	.	.	.
cord-329515-ra20actc	300	1	As	as	IN
cord-329515-ra20actc	300	2	shown	show	VBN
cord-329515-ra20actc	300	3	in	in	IN
cord-329515-ra20actc	300	4	Fig	Fig	NNP
cord-329515-ra20actc	300	5	.	.	.
cord-329515-ra20actc	301	1	11	11	CD
cord-329515-ra20actc	302	1	A	a	DT
cord-329515-ra20actc	302	2	there	there	EX
cord-329515-ra20actc	302	3	was	be	VBD
cord-329515-ra20actc	302	4	a	a	DT
cord-329515-ra20actc	302	5	pH	pH	NNP
cord-329515-ra20actc	302	6	dependent	dependent	JJ
cord-329515-ra20actc	302	7	shift	shift	NN
cord-329515-ra20actc	302	8	of	of	IN
cord-329515-ra20actc	302	9	1363	1363	CD
cord-329515-ra20actc	302	10	from	from	IN
cord-329515-ra20actc	302	11	the	the	DT
cord-329515-ra20actc	302	12	soluble	soluble	JJ
cord-329515-ra20actc	302	13	fraction	fraction	NN
cord-329515-ra20actc	302	14	to	to	IN
cord-329515-ra20actc	302	15	the	the	DT
cord-329515-ra20actc	302	16	pellet	pellet	NN
cord-329515-ra20actc	302	17	.	.	.
cord-329515-ra20actc	303	1	At	at	IN
cord-329515-ra20actc	303	2	pH	pH	NNP
cord-329515-ra20actc	303	3	8.0	8.0	CD
cord-329515-ra20actc	303	4	,	,	,
cord-329515-ra20actc	303	5	p63	p63	CD
cord-329515-ra20actc	303	6	was	be	VBD
cord-329515-ra20actc	303	7	equally	equally	RB
cord-329515-ra20actc	303	8	distributed	distribute	VBN
cord-329515-ra20actc	303	9	between	between	IN
cord-329515-ra20actc	303	10	the	the	DT
cord-329515-ra20actc	303	11	pellet	pellet	NN
cord-329515-ra20actc	303	12	and	and	CC
cord-329515-ra20actc	303	13	supernatant	supernatant	JJ
cord-329515-ra20actc	303	14	fractions	fraction	NNS
cord-329515-ra20actc	303	15	,	,	,
cord-329515-ra20actc	303	16	whereas	whereas	IN
cord-329515-ra20actc	303	17	increasing	increase	VBG
cord-329515-ra20actc	303	18	amounts	amount	NNS
cord-329515-ra20actc	303	19	of	of	IN
cord-329515-ra20actc	303	20	p63	p63	CD
cord-329515-ra20actc	303	21	were	be	VBD
cord-329515-ra20actc	303	22	recovered	recover	VBN
cord-329515-ra20actc	303	23	in	in	IN
cord-329515-ra20actc	303	24	the	the	DT
cord-329515-ra20actc	303	25	COS	COS	NNP
cord-329515-ra20actc	303	26	cells	cell	NNS
cord-329515-ra20actc	303	27	transfected	transfecte	VBN
cord-329515-ra20actc	303	28	with	with	IN
cord-329515-ra20actc	303	29	p63wt	p63wt	NNP
cord-329515-ra20actc	303	30	were	be	VBD
cord-329515-ra20actc	303	31	solubilized	solubilize	VBN
cord-329515-ra20actc	303	32	with	with	IN
cord-329515-ra20actc	303	33	Triton	Triton	NNP
cord-329515-ra20actc	303	34	X-100	x-100	RB
cord-329515-ra20actc	303	35	at	at	IN
cord-329515-ra20actc	303	36	the	the	DT
cord-329515-ra20actc	303	37	indicated	indicate	VBN
cord-329515-ra20actc	303	38	pHs	pHs	NNP
cord-329515-ra20actc	303	39	and	and	CC
cord-329515-ra20actc	303	40	then	then	RB
cord-329515-ra20actc	303	41	separated	separate	VBN
cord-329515-ra20actc	303	42	by	by	IN
cord-329515-ra20actc	303	43	centrifugation	centrifugation	NN
cord-329515-ra20actc	303	44	at	at	IN
cord-329515-ra20actc	303	45	100,000	100,000	CD
cord-329515-ra20actc	303	46	g	g	NN
cord-329515-ra20actc	303	47	into	into	IN
cord-329515-ra20actc	303	48	supernatant	supernatant	NN
cord-329515-ra20actc	303	49	(	(	-LRB-
cord-329515-ra20actc	303	50	S	s	NN
cord-329515-ra20actc	303	51	)	)	-RRB-
cord-329515-ra20actc	303	52	and	and	CC
cord-329515-ra20actc	303	53	pellet	pellet	NN
cord-329515-ra20actc	303	54	(	(	-LRB-
cord-329515-ra20actc	303	55	P	p	NN
cord-329515-ra20actc	303	56	)	)	-RRB-
cord-329515-ra20actc	303	57	.	.	.
cord-329515-ra20actc	304	1	Proteins	protein	NNS
cord-329515-ra20actc	304	2	of	of	IN
cord-329515-ra20actc	304	3	the	the	DT
cord-329515-ra20actc	304	4	two	two	CD
cord-329515-ra20actc	304	5	fractions	fraction	NNS
cord-329515-ra20actc	304	6	were	be	VBD
cord-329515-ra20actc	304	7	subjected	subject	VBN
cord-329515-ra20actc	304	8	to	to	IN
cord-329515-ra20actc	304	9	SDS	SDS	NNP
cord-329515-ra20actc	304	10	-	-	HYPH
cord-329515-ra20actc	304	11	PAGE	PAGE	NNP
cord-329515-ra20actc	304	12	(	(	-LRB-
cord-329515-ra20actc	304	13	8	8	CD
cord-329515-ra20actc	304	14	%	%	NN
cord-329515-ra20actc	304	15	gels	gel	NNS
cord-329515-ra20actc	304	16	)	)	-RRB-
cord-329515-ra20actc	304	17	and	and	CC
cord-329515-ra20actc	304	18	immunoblotring	immunoblotre	VBG
cord-329515-ra20actc	304	19	with	with	IN
cord-329515-ra20actc	304	20	an	an	DT
cord-329515-ra20actc	304	21	anti	anti	JJ
cord-329515-ra20actc	304	22	-	-	JJ
cord-329515-ra20actc	304	23	p63	p63	JJ
cord-329515-ra20actc	304	24	mAb	mAb	NNS
cord-329515-ra20actc	304	25	.	.	.
cord-329515-ra20actc	305	1	The	the	DT
cord-329515-ra20actc	305	2	numbers	number	NNS
cord-329515-ra20actc	305	3	at	at	IN
cord-329515-ra20actc	305	4	the	the	DT
cord-329515-ra20actc	305	5	left	left	JJ
cord-329515-ra20actc	305	6	margin	margin	NN
cord-329515-ra20actc	305	7	of	of	IN
cord-329515-ra20actc	305	8	the	the	DT
cord-329515-ra20actc	305	9	blot	blot	NN
cord-329515-ra20actc	305	10	indicate	indicate	VBP
cord-329515-ra20actc	305	11	known	know	VBN
cord-329515-ra20actc	305	12	molecular	molecular	JJ
cord-329515-ra20actc	305	13	mass	mass	NN
cord-329515-ra20actc	305	14	in	in	IN
cord-329515-ra20actc	305	15	kilodalton	kilodalton	NNP
cord-329515-ra20actc	305	16	.	.	.
cord-329515-ra20actc	306	1	(	(	-LRB-
cord-329515-ra20actc	306	2	B	b	NN
cord-329515-ra20actc	306	3	)	)	-RRB-
cord-329515-ra20actc	306	4	Samples	sample	NNS
cord-329515-ra20actc	306	5	of	of	IN
cord-329515-ra20actc	306	6	affinity	affinity	NN
cord-329515-ra20actc	306	7	purified	purify	VBN
cord-329515-ra20actc	306	8	p63wt	p63wt	NNP
cord-329515-ra20actc	306	9	protein	protein	NN
cord-329515-ra20actc	306	10	(	(	-LRB-
cord-329515-ra20actc	306	11	lanes	lane	NNS
cord-329515-ra20actc	306	12	1	1	CD
cord-329515-ra20actc	306	13	-	-	SYM
cord-329515-ra20actc	306	14	6	6	CD
cord-329515-ra20actc	306	15	)	)	-RRB-
cord-329515-ra20actc	306	16	or	or	CC
cord-329515-ra20actc	306	17	A2	A2	NNP
cord-329515-ra20actc	306	18	-	-	HYPH
cord-329515-ra20actc	306	19	101AA	101AA	NNP
cord-329515-ra20actc	306	20	(	(	-LRB-
cord-329515-ra20actc	306	21	lanes	lane	NNS
cord-329515-ra20actc	306	22	7	7	CD
cord-329515-ra20actc	306	23	-	-	SYM
cord-329515-ra20actc	306	24	10	10	CD
cord-329515-ra20actc	306	25	)	)	-RRB-
cord-329515-ra20actc	306	26	in	in	IN
cord-329515-ra20actc	307	1	MNT	MNT	NNP
cord-329515-ra20actc	307	2	pH	pH	NNP
cord-329515-ra20actc	307	3	8.0-Triton	8.0-triton	CD
cord-329515-ra20actc	307	4	X-100	x-100	NN
cord-329515-ra20actc	307	5	were	be	VBD
cord-329515-ra20actc	307	6	incubated	incubate	VBN
cord-329515-ra20actc	307	7	for	for	IN
cord-329515-ra20actc	307	8	40	40	CD
cord-329515-ra20actc	307	9	rain	rain	NN
cord-329515-ra20actc	307	10	(	(	-LRB-
cord-329515-ra20actc	307	11	I	i	NN
cord-329515-ra20actc	307	12	)	)	-RRB-
cord-329515-ra20actc	307	13	,	,	,
cord-329515-ra20actc	307	14	adjusted	adjust	VBN
cord-329515-ra20actc	307	15	to	to	IN
cord-329515-ra20actc	307	16	pH	pH	NNP
cord-329515-ra20actc	307	17	5.8	5.8	CD
cord-329515-ra20actc	307	18	and	and	CC
cord-329515-ra20actc	307	19	then	then	RB
cord-329515-ra20actc	307	20	incubated	incubate	VBD
cord-329515-ra20actc	307	21	for	for	IN
cord-329515-ra20actc	307	22	40	40	CD
cord-329515-ra20actc	307	23	rain	rain	NN
cord-329515-ra20actc	307	24	(	(	-LRB-
cord-329515-ra20actc	307	25	II	II	NNP
cord-329515-ra20actc	307	26	)	)	-RRB-
cord-329515-ra20actc	307	27	,	,	,
cord-329515-ra20actc	307	28	or	or	CC
cord-329515-ra20actc	307	29	shifted	shift	VBD
cord-329515-ra20actc	307	30	to	to	IN
cord-329515-ra20actc	307	31	pH	pH	NNP
cord-329515-ra20actc	307	32	5.8	5.8	CD
cord-329515-ra20actc	307	33	for	for	IN
cord-329515-ra20actc	307	34	40	40	CD
cord-329515-ra20actc	307	35	mill	mill	NN
cord-329515-ra20actc	307	36	,	,	,
cord-329515-ra20actc	307	37	then	then	RB
cord-329515-ra20actc	307	38	returned	return	VBD
cord-329515-ra20actc	307	39	to	to	IN
cord-329515-ra20actc	307	40	pH	pH	NNP
cord-329515-ra20actc	307	41	8.0	8.0	CD
cord-329515-ra20actc	307	42	and	and	CC
cord-329515-ra20actc	307	43	incubated	incubate	VBN
cord-329515-ra20actc	307	44	for	for	IN
cord-329515-ra20actc	307	45	another	another	DT
cord-329515-ra20actc	307	46	40	40	CD
cord-329515-ra20actc	307	47	rain	rain	NN
cord-329515-ra20actc	307	48	(	(	-LRB-
cord-329515-ra20actc	307	49	III	III	NNP
cord-329515-ra20actc	307	50	)	)	-RRB-
cord-329515-ra20actc	307	51	.	.	.
cord-329515-ra20actc	308	1	Separation	separation	NN
cord-329515-ra20actc	308	2	into	into	IN
cord-329515-ra20actc	308	3	supernatant	supernatant	NN
cord-329515-ra20actc	308	4	(	(	-LRB-
cord-329515-ra20actc	308	5	S	s	NN
cord-329515-ra20actc	308	6	)	)	-RRB-
cord-329515-ra20actc	308	7	and	and	CC
cord-329515-ra20actc	308	8	pellet	pellet	NN
cord-329515-ra20actc	308	9	(	(	-LRB-
cord-329515-ra20actc	308	10	P	p	NN
cord-329515-ra20actc	308	11	)	)	-RRB-
cord-329515-ra20actc	308	12	and	and	CC
cord-329515-ra20actc	308	13	further	further	JJ
cord-329515-ra20actc	308	14	analysis	analysis	NN
cord-329515-ra20actc	308	15	was	be	VBD
cord-329515-ra20actc	308	16	as	as	IN
cord-329515-ra20actc	308	17	described	describe	VBN
cord-329515-ra20actc	308	18	in	in	IN
cord-329515-ra20actc	308	19	A.	a.	NN
cord-329515-ra20actc	308	20	pellet	pellet	NN
cord-329515-ra20actc	308	21	as	as	IN
cord-329515-ra20actc	308	22	the	the	DT
cord-329515-ra20actc	308	23	pH	pH	NNP
cord-329515-ra20actc	308	24	decreased	decrease	VBD
cord-329515-ra20actc	308	25	.	.	.
cord-329515-ra20actc	309	1	When	when	WRB
cord-329515-ra20actc	309	2	the	the	DT
cord-329515-ra20actc	309	3	experiment	experiment	NN
cord-329515-ra20actc	309	4	was	be	VBD
cord-329515-ra20actc	309	5	performed	perform	VBN
cord-329515-ra20actc	309	6	with	with	IN
cord-329515-ra20actc	309	7	nontransfected	nontransfected	JJ
cord-329515-ra20actc	309	8	COS	COS	NNP
cord-329515-ra20actc	309	9	cells	cell	NNS
cord-329515-ra20actc	309	10	at	at	IN
cord-329515-ra20actc	309	11	pH	pH	NNP
cord-329515-ra20actc	309	12	7.4	7.4	CD
cord-329515-ra20actc	309	13	,	,	,
cord-329515-ra20actc	309	14	94	94	CD
cord-329515-ra20actc	309	15	+	+	SYM
cord-329515-ra20actc	309	16	8	8	CD
cord-329515-ra20actc	309	17	%	%	NN
cord-329515-ra20actc	309	18	of	of	IN
cord-329515-ra20actc	309	19	the	the	DT
cord-329515-ra20actc	309	20	endogenous	endogenous	JJ
cord-329515-ra20actc	309	21	p63	p63	CD
cord-329515-ra20actc	309	22	was	be	VBD
cord-329515-ra20actc	309	23	recovered	recover	VBN
cord-329515-ra20actc	309	24	in	in	IN
cord-329515-ra20actc	309	25	the	the	DT
cord-329515-ra20actc	309	26	pellet	pellet	NN
cord-329515-ra20actc	309	27	fraction	fraction	NN
cord-329515-ra20actc	309	28	.	.	.
cord-329515-ra20actc	310	1	This	this	DT
cord-329515-ra20actc	310	2	demonstrates	demonstrate	VBZ
cord-329515-ra20actc	310	3	that	that	IN
cord-329515-ra20actc	310	4	p63	p63	CD
cord-329515-ra20actc	310	5	oligomerization	oligomerization	NN
cord-329515-ra20actc	310	6	occurs	occur	VBZ
cord-329515-ra20actc	310	7	at	at	IN
cord-329515-ra20actc	310	8	physiologic	physiologic	JJ
cord-329515-ra20actc	310	9	protein	protein	NN
cord-329515-ra20actc	310	10	concentrations	concentration	NNS
cord-329515-ra20actc	310	11	,	,	,
cord-329515-ra20actc	310	12	excluding	exclude	VBG
cord-329515-ra20actc	310	13	the	the	DT
cord-329515-ra20actc	310	14	possibility	possibility	NN
cord-329515-ra20actc	310	15	that	that	IN
cord-329515-ra20actc	310	16	this	this	DT
cord-329515-ra20actc	310	17	property	property	NN
cord-329515-ra20actc	310	18	is	be	VBZ
cord-329515-ra20actc	310	19	a	a	DT
cord-329515-ra20actc	310	20	special	special	JJ
cord-329515-ra20actc	310	21	feature	feature	NN
cord-329515-ra20actc	310	22	of	of	IN
cord-329515-ra20actc	310	23	transfection	transfection	NN
cord-329515-ra20actc	310	24	and/or	and/or	CC
cord-329515-ra20actc	310	25	overexpression	overexpression	NN
cord-329515-ra20actc	310	26	.	.	.
cord-329515-ra20actc	311	1	Similar	similar	JJ
cord-329515-ra20actc	311	2	results	result	NNS
cord-329515-ra20actc	311	3	were	be	VBD
cord-329515-ra20actc	311	4	obtained	obtain	VBN
cord-329515-ra20actc	311	5	with	with	IN
cord-329515-ra20actc	311	6	affinity	affinity	NN
cord-329515-ra20actc	311	7	-	-	HYPH
cord-329515-ra20actc	311	8	purified	purify	VBN
cord-329515-ra20actc	311	9	p63	p63	NN
cord-329515-ra20actc	311	10	,	,	,
cord-329515-ra20actc	311	11	as	as	IN
cord-329515-ra20actc	311	12	shown	show	VBN
cord-329515-ra20actc	311	13	in	in	IN
cord-329515-ra20actc	311	14	Fig	Fig	NNP
cord-329515-ra20actc	311	15	.	.	.
cord-329515-ra20actc	312	1	11	11	CD
cord-329515-ra20actc	312	2	B	b	NN
cord-329515-ra20actc	312	3	(	(	-LRB-
cord-329515-ra20actc	312	4	lanes	lane	NNS
cord-329515-ra20actc	312	5	1	1	CD
cord-329515-ra20actc	312	6	-	-	SYM
cord-329515-ra20actc	312	7	6	6	CD
cord-329515-ra20actc	312	8	)	)	-RRB-
cord-329515-ra20actc	312	9	.	.	.
cord-329515-ra20actc	313	1	In	in	IN
cord-329515-ra20actc	313	2	this	this	DT
cord-329515-ra20actc	313	3	experiment	experiment	NN
cord-329515-ra20actc	313	4	,	,	,
cord-329515-ra20actc	313	5	purified	purify	VBN
cord-329515-ra20actc	313	6	p63	p63	NNS
cord-329515-ra20actc	313	7	kept	keep	VBN
cord-329515-ra20actc	313	8	at	at	IN
cord-329515-ra20actc	313	9	pH	pH	NNP
cord-329515-ra20actc	313	10	8.0	8.0	CD
cord-329515-ra20actc	313	11	remained	remain	VBD
cord-329515-ra20actc	313	12	completely	completely	RB
cord-329515-ra20actc	313	13	soluble	soluble	JJ
cord-329515-ra20actc	313	14	(	(	-LRB-
cord-329515-ra20actc	313	15	lanes	lane	NNS
cord-329515-ra20actc	313	16	1	1	CD
cord-329515-ra20actc	313	17	and	and	CC
cord-329515-ra20actc	313	18	2	2	CD
cord-329515-ra20actc	313	19	)	)	-RRB-
cord-329515-ra20actc	313	20	.	.	.
cord-329515-ra20actc	314	1	When	when	WRB
cord-329515-ra20actc	314	2	the	the	DT
cord-329515-ra20actc	314	3	pH	pH	NNP
cord-329515-ra20actc	314	4	was	be	VBD
cord-329515-ra20actc	314	5	shifted	shift	VBN
cord-329515-ra20actc	314	6	to	to	IN
cord-329515-ra20actc	314	7	5.8	5.8	CD
cord-329515-ra20actc	314	8	,	,	,
cord-329515-ra20actc	314	9	about	about	RB
cord-329515-ra20actc	314	10	half	half	NN
cord-329515-ra20actc	314	11	of	of	IN
cord-329515-ra20actc	314	12	the	the	DT
cord-329515-ra20actc	314	13	proteins	protein	NNS
cord-329515-ra20actc	314	14	formed	form	VBD
cord-329515-ra20actc	314	15	oligomers	oligomer	NNS
cord-329515-ra20actc	314	16	that	that	WDT
cord-329515-ra20actc	314	17	sedimented	sediment	VBD
cord-329515-ra20actc	314	18	at	at	IN
cord-329515-ra20actc	314	19	100,000	100,000	CD
cord-329515-ra20actc	314	20	g	g	NN
cord-329515-ra20actc	314	21	centrifugation	centrifugation	NN
cord-329515-ra20actc	314	22	(	(	-LRB-
cord-329515-ra20actc	314	23	lanes	lane	NNS
cord-329515-ra20actc	314	24	3	3	CD
cord-329515-ra20actc	314	25	and	and	CC
cord-329515-ra20actc	314	26	4	4	CD
cord-329515-ra20actc	314	27	)	)	-RRB-
cord-329515-ra20actc	314	28	.	.	.
cord-329515-ra20actc	315	1	This	this	DT
cord-329515-ra20actc	315	2	oligomerization	oligomerization	NN
cord-329515-ra20actc	315	3	was	be	VBD
cord-329515-ra20actc	315	4	completely	completely	RB
cord-329515-ra20actc	315	5	reversed	reverse	VBN
cord-329515-ra20actc	315	6	by	by	IN
cord-329515-ra20actc	315	7	restoring	restore	VBG
cord-329515-ra20actc	315	8	the	the	DT
cord-329515-ra20actc	315	9	pH	pH	NNP
cord-329515-ra20actc	315	10	to	to	IN
cord-329515-ra20actc	315	11	8.0	8.0	CD
cord-329515-ra20actc	315	12	(	(	-LRB-
cord-329515-ra20actc	315	13	lanes	lane	NNS
cord-329515-ra20actc	315	14	5	5	CD
cord-329515-ra20actc	315	15	and	and	CC
cord-329515-ra20actc	315	16	6	6	CD
cord-329515-ra20actc	315	17	)	)	-RRB-
cord-329515-ra20actc	315	18	.	.	.
cord-329515-ra20actc	316	1	Taken	take	VBN
cord-329515-ra20actc	316	2	together	together	RB
cord-329515-ra20actc	316	3	,	,	,
cord-329515-ra20actc	316	4	these	these	DT
cord-329515-ra20actc	316	5	results	result	NNS
cord-329515-ra20actc	316	6	indicate	indicate	VBP
cord-329515-ra20actc	316	7	that	that	IN
cord-329515-ra20actc	316	8	p63	p63	CD
cord-329515-ra20actc	316	9	forms	form	NNS
cord-329515-ra20actc	316	10	Triton	Triton	NNP
cord-329515-ra20actc	316	11	X-100-insoluble	x-100-insoluble	JJ
cord-329515-ra20actc	316	12	oligomers	oligomer	NNS
cord-329515-ra20actc	316	13	,	,	,
cord-329515-ra20actc	316	14	especially	especially	RB
cord-329515-ra20actc	316	15	at	at	IN
cord-329515-ra20actc	316	16	neutral	neutral	JJ
cord-329515-ra20actc	316	17	pH	pH	NNP
cord-329515-ra20actc	316	18	and	and	CC
cord-329515-ra20actc	316	19	below	below	RB
cord-329515-ra20actc	316	20	.	.	.
cord-329515-ra20actc	317	1	We	-PRON-	PRP
cord-329515-ra20actc	317	2	next	next	RB
cord-329515-ra20actc	317	3	tested	test	VBD
cord-329515-ra20actc	317	4	whether	whether	IN
cord-329515-ra20actc	317	5	the	the	DT
cord-329515-ra20actc	317	6	ability	ability	NN
cord-329515-ra20actc	317	7	of	of	IN
cord-329515-ra20actc	317	8	p63	p63	CD
cord-329515-ra20actc	317	9	to	to	IN
cord-329515-ra20actc	317	10	oligomerize	oligomerize	NNP
cord-329515-ra20actc	317	11	correlated	correlate	VBN
cord-329515-ra20actc	317	12	with	with	IN
cord-329515-ra20actc	317	13	retention	retention	NN
cord-329515-ra20actc	317	14	and	and	CC
cord-329515-ra20actc	317	15	proper	proper	JJ
cord-329515-ra20actc	317	16	localization	localization	NN
cord-329515-ra20actc	317	17	.	.	.
cord-329515-ra20actc	318	1	To	to	TO
cord-329515-ra20actc	318	2	address	address	VB
cord-329515-ra20actc	318	3	this	this	DT
cord-329515-ra20actc	318	4	point	point	NN
cord-329515-ra20actc	318	5	,	,	,
cord-329515-ra20actc	318	6	a	a	DT
cord-329515-ra20actc	318	7	selected	select	VBN
cord-329515-ra20actc	318	8	set	set	NN
cord-329515-ra20actc	318	9	of	of	IN
cord-329515-ra20actc	318	10	p63	p63	CD
cord-329515-ra20actc	318	11	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	318	12	tall	tall	JJ
cord-329515-ra20actc	318	13	mutants	mutant	NNS
cord-329515-ra20actc	318	14	were	be	VBD
cord-329515-ra20actc	318	15	expressed	express	VBN
cord-329515-ra20actc	318	16	in	in	IN
cord-329515-ra20actc	318	17	COS	COS	NNP
cord-329515-ra20actc	318	18	cells	cell	NNS
cord-329515-ra20actc	318	19	and	and	CC
cord-329515-ra20actc	318	20	the	the	DT
cord-329515-ra20actc	318	21	transfected	transfecte	VBN
cord-329515-ra20actc	318	22	ceils	ceil	NNS
cord-329515-ra20actc	318	23	were	be	VBD
cord-329515-ra20actc	318	24	then	then	RB
cord-329515-ra20actc	318	25	solubilized	solubilize	VBN
cord-329515-ra20actc	318	26	with	with	IN
cord-329515-ra20actc	318	27	Triton	Triton	NNP
cord-329515-ra20actc	318	28	X-100	x-100	RB
cord-329515-ra20actc	318	29	at	at	IN
cord-329515-ra20actc	318	30	pH	pH	NNP
cord-329515-ra20actc	318	31	6.5	6.5	CD
cord-329515-ra20actc	318	32	and	and	CC
cord-329515-ra20actc	318	33	analyzed	analyze	VBD
cord-329515-ra20actc	318	34	as	as	IN
cord-329515-ra20actc	318	35	described	describe	VBN
cord-329515-ra20actc	318	36	above	above	RB
cord-329515-ra20actc	318	37	.	.	.
cord-329515-ra20actc	319	1	The	the	DT
cord-329515-ra20actc	319	2	results	result	NNS
cord-329515-ra20actc	319	3	of	of	IN
cord-329515-ra20actc	319	4	a	a	DT
cord-329515-ra20actc	319	5	typical	typical	JJ
cord-329515-ra20actc	319	6	experiment	experiment	NN
cord-329515-ra20actc	319	7	are	be	VBP
cord-329515-ra20actc	319	8	shown	show	VBN
cord-329515-ra20actc	319	9	in	in	IN
cord-329515-ra20actc	319	10	Fig	Fig	NNP
cord-329515-ra20actc	319	11	.	.	.
cord-329515-ra20actc	320	1	12	12	CD
cord-329515-ra20actc	320	2	A	a	NN
cord-329515-ra20actc	320	3	and	and	CC
cord-329515-ra20actc	320	4	the	the	DT
cord-329515-ra20actc	320	5	quantitation	quantitation	NN
cord-329515-ra20actc	320	6	of	of	IN
cord-329515-ra20actc	320	7	multiple	multiple	JJ
cord-329515-ra20actc	320	8	experiments	experiment	NNS
cord-329515-ra20actc	320	9	is	be	VBZ
cord-329515-ra20actc	320	10	given	give	VBN
cord-329515-ra20actc	320	11	in	in	IN
cord-329515-ra20actc	320	12	Fig	Fig	NNP
cord-329515-ra20actc	320	13	.	.	.
cord-329515-ra20actc	321	1	12	12	CD
cord-329515-ra20actc	322	1	B.	B.	NNP
cord-329515-ra20actc	322	2	P63wt	P63wt	NNP
cord-329515-ra20actc	322	3	which	which	WDT
cord-329515-ra20actc	322	4	served	serve	VBD
cord-329515-ra20actc	322	5	as	as	IN
cord-329515-ra20actc	322	6	a	a	DT
cord-329515-ra20actc	322	7	control	control	NN
cord-329515-ra20actc	322	8	was	be	VBD
cord-329515-ra20actc	322	9	exclusively	exclusively	RB
cord-329515-ra20actc	322	10	found	find	VBN
cord-329515-ra20actc	322	11	in	in	IN
cord-329515-ra20actc	322	12	the	the	DT
cord-329515-ra20actc	322	13	pellet	pellet	NN
cord-329515-ra20actc	322	14	fraction	fraction	NN
cord-329515-ra20actc	322	15	(	(	-LRB-
cord-329515-ra20actc	322	16	97	97	CD
cord-329515-ra20actc	322	17	±	±	CD
cord-329515-ra20actc	322	18	5	5	CD
cord-329515-ra20actc	322	19	%	%	NN
cord-329515-ra20actc	322	20	)	)	-RRB-
cord-329515-ra20actc	322	21	.	.	.
cord-329515-ra20actc	323	1	A24	A24	NNP
cord-329515-ra20actc	323	2	-	-	HYPH
cord-329515-ra20actc	323	3	101	101	CD
cord-329515-ra20actc	323	4	,	,	,
cord-329515-ra20actc	323	5	MP2	MP2	NNP
cord-329515-ra20actc	323	6	,	,	,
cord-329515-ra20actc	323	7	and	and	CC
cord-329515-ra20actc	323	8	MP3	mp3	NN
cord-329515-ra20actc	323	9	which	which	WDT
cord-329515-ra20actc	323	10	have	have	VBP
cord-329515-ra20actc	323	11	intraceilular	intraceilular	JJ
cord-329515-ra20actc	323	12	distributions	distribution	NNS
cord-329515-ra20actc	323	13	COS	COS	NNP
cord-329515-ra20actc	323	14	ceils	ceil	NNS
cord-329515-ra20actc	323	15	were	be	VBD
cord-329515-ra20actc	323	16	trmsfeoed	trmsfeoed	NN
cord-329515-ra20actc	323	17	with	with	IN
cord-329515-ra20actc	323	18	wt	wt	NN
cord-329515-ra20actc	323	19	or	or	CC
cord-329515-ra20actc	323	20	mutant	mutant	JJ
cord-329515-ra20actc	323	21	p63	p63	NN
cord-329515-ra20actc	323	22	,	,	,
cord-329515-ra20actc	323	23	solubRized	solubrize	VBN
cord-329515-ra20actc	323	24	with	with	IN
cord-329515-ra20actc	323	25	Triton	Triton	NNP
cord-329515-ra20actc	324	1	X-100	x-100	RB
cord-329515-ra20actc	324	2	at	at	IN
cord-329515-ra20actc	324	3	pH	pH	NNP
cord-329515-ra20actc	324	4	6.5	6.5	CD
cord-329515-ra20actc	324	5	and	and	CC
cord-329515-ra20actc	324	6	further	further	RB
cord-329515-ra20actc	324	7	analyzed	analyze	VBN
cord-329515-ra20actc	324	8	as	as	IN
cord-329515-ra20actc	324	9	described	describe	VBN
cord-329515-ra20actc	324	10	in	in	IN
cord-329515-ra20actc	324	11	Fig	Fig	NNP
cord-329515-ra20actc	324	12	.	.	.
cord-329515-ra20actc	324	13	 	 	_SP
cord-329515-ra20actc	325	1	11	11	CD
cord-329515-ra20actc	325	2	.	.	.
cord-329515-ra20actc	326	1	(	(	-LRB-
cord-329515-ra20actc	326	2	P	p	NN
cord-329515-ra20actc	326	3	)	)	-RRB-
cord-329515-ra20actc	326	4	pellet	pellet	NN
cord-329515-ra20actc	326	5	,	,	,
cord-329515-ra20actc	326	6	(	(	-LRB-
cord-329515-ra20actc	326	7	S	s	NN
cord-329515-ra20actc	326	8	)	)	-RRB-
cord-329515-ra20actc	326	9	supematant	supematant	NN
cord-329515-ra20actc	326	10	.	.	.
cord-329515-ra20actc	327	1	The	the	DT
cord-329515-ra20actc	327	2	upper	upper	JJ
cord-329515-ra20actc	327	3	band	band	NN
cord-329515-ra20actc	327	4	seen	see	VBN
cord-329515-ra20actc	327	5	in	in	IN
cord-329515-ra20actc	327	6	the	the	DT
cord-329515-ra20actc	327	7	pellet	pellet	NN
cord-329515-ra20actc	327	8	lanes	lane	NNS
cord-329515-ra20actc	327	9	of	of	IN
cord-329515-ra20actc	327	10	p63	p63	CD
cord-329515-ra20actc	327	11	mutants	mutant	NNS
cord-329515-ra20actc	327	12	represents	represent	VBZ
cord-329515-ra20actc	327	13	endogenous	endogenous	JJ
cord-329515-ra20actc	327	14	p63	p63	NN
cord-329515-ra20actc	327	15	that	that	WDT
cord-329515-ra20actc	327	16	is	be	VBZ
cord-329515-ra20actc	327	17	exclusively	exclusively	RB
cord-329515-ra20actc	327	18	found	find	VBN
cord-329515-ra20actc	327	19	in	in	IN
cord-329515-ra20actc	327	20	the	the	DT
cord-329515-ra20actc	327	21	pellet	pellet	NN
cord-329515-ra20actc	327	22	fractions	fraction	NNS
cord-329515-ra20actc	327	23	.	.	.
cord-329515-ra20actc	328	1	(	(	-LRB-
cord-329515-ra20actc	328	2	B	b	NN
cord-329515-ra20actc	328	3	)	)	-RRB-
cord-329515-ra20actc	329	1	The	the	DT
cord-329515-ra20actc	329	2	immtmoblots	immtmoblot	NNS
cord-329515-ra20actc	329	3	shown	show	VBN
cord-329515-ra20actc	329	4	in	in	IN
cord-329515-ra20actc	329	5	A	a	NN
cord-329515-ra20actc	329	6	and	and	CC
cord-329515-ra20actc	329	7	those	those	DT
cord-329515-ra20actc	329	8	from	from	IN
cord-329515-ra20actc	329	9	additional	additional	JJ
cord-329515-ra20actc	329	10	experiments	experiment	NNS
cord-329515-ra20actc	329	11	were	be	VBD
cord-329515-ra20actc	329	12	quantitated	quantitate	VBN
cord-329515-ra20actc	329	13	by	by	IN
cord-329515-ra20actc	329	14	densitometric	densitometric	JJ
cord-329515-ra20actc	329	15	scanning	scanning	NN
cord-329515-ra20actc	329	16	.	.	.
cord-329515-ra20actc	330	1	For	for	IN
cord-329515-ra20actc	330	2	each	each	DT
cord-329515-ra20actc	330	3	sample	sample	NN
cord-329515-ra20actc	330	4	(	(	-LRB-
cord-329515-ra20actc	330	5	x	x	NN
cord-329515-ra20actc	330	6	-	-	HYPH
cord-329515-ra20actc	330	7	axis	axis	NN
cord-329515-ra20actc	330	8	)	)	-RRB-
cord-329515-ra20actc	331	1	the	the	DT
cord-329515-ra20actc	331	2	amount	amount	NN
cord-329515-ra20actc	331	3	of	of	IN
cord-329515-ra20actc	331	4	wt	wt	NN
cord-329515-ra20actc	331	5	or	or	CC
cord-329515-ra20actc	331	6	mutant	mutant	JJ
cord-329515-ra20actc	331	7	1063	1063	CD
cord-329515-ra20actc	331	8	detected	detect	VBN
cord-329515-ra20actc	331	9	in	in	IN
cord-329515-ra20actc	331	10	the	the	DT
cord-329515-ra20actc	331	11	supernatant	supernatant	NN
cord-329515-ra20actc	331	12	(	(	-LRB-
cord-329515-ra20actc	331	13	dotted	dotted	JJ
cord-329515-ra20actc	331	14	light	light	JJ
cord-329515-ra20actc	331	15	bars	bar	NNS
cord-329515-ra20actc	331	16	)	)	-RRB-
cord-329515-ra20actc	331	17	and	and	CC
cord-329515-ra20actc	331	18	pellet	pellet	NN
cord-329515-ra20actc	331	19	(	(	-LRB-
cord-329515-ra20actc	331	20	striated	striated	JJ
cord-329515-ra20actc	331	21	dark	dark	JJ
cord-329515-ra20actc	331	22	bars	bar	NNS
cord-329515-ra20actc	331	23	)	)	-RRB-
cord-329515-ra20actc	331	24	fraction	fraction	NN
cord-329515-ra20actc	331	25	,	,	,
cord-329515-ra20actc	331	26	respectively	respectively	RB
cord-329515-ra20actc	331	27	,	,	,
cord-329515-ra20actc	331	28	is	be	VBZ
cord-329515-ra20actc	331	29	plotted	plot	VBN
cord-329515-ra20actc	331	30	as	as	IN
cord-329515-ra20actc	331	31	the	the	DT
cord-329515-ra20actc	331	32	percentage	percentage	NN
cord-329515-ra20actc	331	33	of	of	IN
cord-329515-ra20actc	331	34	p63	p63	CD
cord-329515-ra20actc	331	35	present	present	JJ
cord-329515-ra20actc	331	36	in	in	IN
cord-329515-ra20actc	331	37	both	both	DT
cord-329515-ra20actc	331	38	fractions	fraction	NNS
cord-329515-ra20actc	331	39	(	(	-LRB-
cord-329515-ra20actc	331	40	y	y	NN
cord-329515-ra20actc	331	41	-	-	HYPH
cord-329515-ra20actc	331	42	axis	axis	NN
cord-329515-ra20actc	331	43	)	)	-RRB-
cord-329515-ra20actc	331	44	.	.	.
cord-329515-ra20actc	332	1	Each	each	DT
cord-329515-ra20actc	332	2	value	value	NN
cord-329515-ra20actc	332	3	is	be	VBZ
cord-329515-ra20actc	332	4	the	the	DT
cord-329515-ra20actc	332	5	average	average	NN
cord-329515-ra20actc	332	6	of	of	IN
cord-329515-ra20actc	332	7	at	at	RB
cord-329515-ra20actc	332	8	least	least	RBS
cord-329515-ra20actc	332	9	four	four	CD
cord-329515-ra20actc	332	10	independent	independent	JJ
cord-329515-ra20actc	332	11	experiments	experiment	NNS
cord-329515-ra20actc	332	12	.	.	.
cord-329515-ra20actc	333	1	The	the	DT
cord-329515-ra20actc	333	2	standard	standard	JJ
cord-329515-ra20actc	333	3	deviations	deviation	NNS
cord-329515-ra20actc	333	4	were	be	VBD
cord-329515-ra20actc	333	5	,	,	,
cord-329515-ra20actc	333	6	g8.5	g8.5	CD
cord-329515-ra20actc	333	7	%	%	NN
cord-329515-ra20actc	333	8	.	.	.
cord-329515-ra20actc	334	1	similar	similar	JJ
cord-329515-ra20actc	334	2	to	to	IN
cord-329515-ra20actc	334	3	p63wt	p63wt	NNP
cord-329515-ra20actc	334	4	were	be	VBD
cord-329515-ra20actc	334	5	also	also	RB
cord-329515-ra20actc	334	6	recovered	recover	VBN
cord-329515-ra20actc	334	7	predominantly	predominantly	RB
cord-329515-ra20actc	334	8	in	in	IN
cord-329515-ra20actc	334	9	the	the	DT
cord-329515-ra20actc	334	10	100,000	100,000	CD
cord-329515-ra20actc	334	11	g	g	NN
cord-329515-ra20actc	334	12	pellet	pellet	NN
cord-329515-ra20actc	334	13	(	(	-LRB-
cord-329515-ra20actc	334	14	81	81	CD
cord-329515-ra20actc	334	15	+	+	SYM
cord-329515-ra20actc	334	16	9	9	CD
cord-329515-ra20actc	334	17	%	%	NN
cord-329515-ra20actc	334	18	,	,	,
cord-329515-ra20actc	334	19	78	78	CD
cord-329515-ra20actc	334	20	+	+	SYM
cord-329515-ra20actc	334	21	4	4	CD
cord-329515-ra20actc	334	22	%	%	NN
cord-329515-ra20actc	334	23	,	,	,
cord-329515-ra20actc	334	24	and77	and77	NNP
cord-329515-ra20actc	334	25	±	±	NNP
cord-329515-ra20actc	334	26	5	5	CD
cord-329515-ra20actc	334	27	%	%	NN
cord-329515-ra20actc	334	28	,	,	,
cord-329515-ra20actc	334	29	respectively	respectively	RB
cord-329515-ra20actc	334	30	)	)	-RRB-
cord-329515-ra20actc	334	31	.	.	.
cord-329515-ra20actc	335	1	In	in	IN
cord-329515-ra20actc	335	2	contrast	contrast	NN
cord-329515-ra20actc	335	3	,	,	,
cord-329515-ra20actc	335	4	A2	A2	NNP
cord-329515-ra20actc	335	5	-	-	HYPH
cord-329515-ra20actc	335	6	101AA	101AA	NNP
cord-329515-ra20actc	335	7	and	and	CC
cord-329515-ra20actc	335	8	MP1	MP1	NNP
cord-329515-ra20actc	335	9	which	which	WDT
cord-329515-ra20actc	335	10	are	be	VBP
cord-329515-ra20actc	335	11	not	not	RB
cord-329515-ra20actc	335	12	localized	localize	VBN
cord-329515-ra20actc	335	13	properly	properly	RB
cord-329515-ra20actc	335	14	,	,	,
cord-329515-ra20actc	335	15	were	be	VBD
cord-329515-ra20actc	335	16	found	find	VBN
cord-329515-ra20actc	335	17	mainly	mainly	RB
cord-329515-ra20actc	335	18	in	in	IN
cord-329515-ra20actc	335	19	the	the	DT
cord-329515-ra20actc	335	20	supernatant	supernatant	JJ
cord-329515-ra20actc	335	21	fraction	fraction	NN
cord-329515-ra20actc	335	22	(	(	-LRB-
cord-329515-ra20actc	335	23	75	75	CD
cord-329515-ra20actc	335	24	±	±	CD
cord-329515-ra20actc	335	25	2	2	CD
cord-329515-ra20actc	335	26	%	%	NN
cord-329515-ra20actc	335	27	,	,	,
cord-329515-ra20actc	335	28	and	and	CC
cord-329515-ra20actc	335	29	83	83	CD
cord-329515-ra20actc	335	30	±	±	CD
cord-329515-ra20actc	335	31	2	2	CD
cord-329515-ra20actc	335	32	%	%	NN
cord-329515-ra20actc	335	33	,	,	,
cord-329515-ra20actc	335	34	respectively	respectively	RB
cord-329515-ra20actc	335	35	)	)	-RRB-
cord-329515-ra20actc	335	36	.	.	.
cord-329515-ra20actc	336	1	The	the	DT
cord-329515-ra20actc	336	2	upper	upper	JJ
cord-329515-ra20actc	336	3	band	band	NN
cord-329515-ra20actc	336	4	detected	detect	VBN
cord-329515-ra20actc	336	5	in	in	IN
cord-329515-ra20actc	336	6	the	the	DT
cord-329515-ra20actc	336	7	pellet	pellet	NN
cord-329515-ra20actc	336	8	lane	lane	NN
cord-329515-ra20actc	336	9	of	of	IN
cord-329515-ra20actc	336	10	each	each	DT
cord-329515-ra20actc	336	11	of	of	IN
cord-329515-ra20actc	336	12	the	the	DT
cord-329515-ra20actc	336	13	p63	p63	CD
cord-329515-ra20actc	336	14	mutants	mutant	NNS
cord-329515-ra20actc	336	15	represents	represent	VBZ
cord-329515-ra20actc	336	16	endogenous	endogenous	JJ
cord-329515-ra20actc	336	17	p63	p63	NN
cord-329515-ra20actc	336	18	from	from	IN
cord-329515-ra20actc	336	19	COS	COS	NNP
cord-329515-ra20actc	336	20	ceils	ceil	NNS
cord-329515-ra20actc	336	21	.	.	.
cord-329515-ra20actc	337	1	Similar	similar	JJ
cord-329515-ra20actc	337	2	to	to	IN
cord-329515-ra20actc	337	3	transfected	transfected	JJ
cord-329515-ra20actc	337	4	p63wt	p63wt	NNP
cord-329515-ra20actc	337	5	,	,	,
cord-329515-ra20actc	337	6	endogenous	endogenous	JJ
cord-329515-ra20actc	337	7	1363	1363	CD
cord-329515-ra20actc	337	8	was	be	VBD
cord-329515-ra20actc	337	9	exclusively	exclusively	RB
cord-329515-ra20actc	337	10	found	find	VBN
cord-329515-ra20actc	337	11	in	in	IN
cord-329515-ra20actc	337	12	the	the	DT
cord-329515-ra20actc	337	13	pellet	pellet	NN
cord-329515-ra20actc	337	14	fraction	fraction	NN
cord-329515-ra20actc	337	15	regardless	regardless	RB
cord-329515-ra20actc	337	16	of	of	IN
cord-329515-ra20actc	337	17	the	the	DT
cord-329515-ra20actc	337	18	behavior	behavior	NN
cord-329515-ra20actc	337	19	of	of	IN
cord-329515-ra20actc	337	20	the	the	DT
cord-329515-ra20actc	337	21	transfected	transfecte	VBN
cord-329515-ra20actc	337	22	p63	p63	CD
cord-329515-ra20actc	337	23	mutants	mutant	NNS
cord-329515-ra20actc	337	24	and	and	CC
cord-329515-ra20actc	337	25	therefore	therefore	RB
cord-329515-ra20actc	337	26	served	serve	VBD
cord-329515-ra20actc	337	27	as	as	IN
cord-329515-ra20actc	337	28	a	a	DT
cord-329515-ra20actc	337	29	useful	useful	JJ
cord-329515-ra20actc	337	30	internal	internal	JJ
cord-329515-ra20actc	337	31	standard	standard	NN
cord-329515-ra20actc	337	32	for	for	IN
cord-329515-ra20actc	337	33	the	the	DT
cord-329515-ra20actc	337	34	distribution	distribution	NN
cord-329515-ra20actc	337	35	of	of	IN
cord-329515-ra20actc	337	36	the	the	DT
cord-329515-ra20actc	337	37	various	various	JJ
cord-329515-ra20actc	337	38	mutants	mutant	NNS
cord-329515-ra20actc	337	39	.	.	.
cord-329515-ra20actc	338	1	Affinity	affinity	NN
cord-329515-ra20actc	338	2	-	-	HYPH
cord-329515-ra20actc	338	3	purified	purify	VBN
cord-329515-ra20actc	338	4	A2	A2	NNP
cord-329515-ra20actc	338	5	-	-	HYPH
cord-329515-ra20actc	338	6	101AA	101AA	NNP
cord-329515-ra20actc	338	7	gave	give	VBD
cord-329515-ra20actc	338	8	similar	similar	JJ
cord-329515-ra20actc	338	9	results	result	NNS
cord-329515-ra20actc	338	10	to	to	IN
cord-329515-ra20actc	338	11	those	those	DT
cord-329515-ra20actc	338	12	obtained	obtain	VBN
cord-329515-ra20actc	338	13	with	with	IN
cord-329515-ra20actc	338	14	homogenates	homogenate	NNS
cord-329515-ra20actc	338	15	of	of	IN
cord-329515-ra20actc	338	16	COS	COS	NNP
cord-329515-ra20actc	338	17	ceils	ceil	NNS
cord-329515-ra20actc	338	18	transfected	transfecte	VBN
cord-329515-ra20actc	338	19	with	with	IN
cord-329515-ra20actc	338	20	A2	A2	NNP
cord-329515-ra20actc	338	21	-	-	HYPH
cord-329515-ra20actc	338	22	101AA	101AA	NNP
cord-329515-ra20actc	339	1	(	(	-LRB-
cord-329515-ra20actc	339	2	Fig	Fig	NNP
cord-329515-ra20actc	339	3	.	.	.
cord-329515-ra20actc	339	4	11	11	CD
cord-329515-ra20actc	339	5	B	b	NN
cord-329515-ra20actc	339	6	,	,	,
cord-329515-ra20actc	339	7	 	 	_SP
cord-329515-ra20actc	339	8	lanes	lane	NNS
cord-329515-ra20actc	339	9	7	7	CD
cord-329515-ra20actc	339	10	-	-	SYM
cord-329515-ra20actc	339	11	10	10	CD
cord-329515-ra20actc	339	12	)	)	-RRB-
cord-329515-ra20actc	339	13	.	.	.
cord-329515-ra20actc	340	1	In	in	IN
cord-329515-ra20actc	340	2	summary	summary	NN
cord-329515-ra20actc	340	3	,	,	,
cord-329515-ra20actc	340	4	the	the	DT
cord-329515-ra20actc	340	5	data	datum	NNS
cord-329515-ra20actc	340	6	show	show	VBP
cord-329515-ra20actc	340	7	a	a	DT
cord-329515-ra20actc	340	8	strong	strong	JJ
cord-329515-ra20actc	340	9	correlation	correlation	NN
cord-329515-ra20actc	340	10	between	between	IN
cord-329515-ra20actc	340	11	retention	retention	NN
cord-329515-ra20actc	340	12	of	of	IN
cord-329515-ra20actc	340	13	p63	p63	CD
cord-329515-ra20actc	340	14	and	and	CC
cord-329515-ra20actc	340	15	the	the	DT
cord-329515-ra20actc	340	16	formation	formation	NN
cord-329515-ra20actc	340	17	of	of	IN
cord-329515-ra20actc	340	18	Triton	Triton	NNP
cord-329515-ra20actc	340	19	X-100-insoluble	X-100-insoluble	NNP
cord-329515-ra20actc	340	20	complexes	complex	NNS
cord-329515-ra20actc	340	21	.	.	.
cord-329515-ra20actc	341	1	Previous	previous	JJ
cord-329515-ra20actc	341	2	studies	study	NNS
cord-329515-ra20actc	341	3	have	have	VBP
cord-329515-ra20actc	341	4	established	establish	VBN
cord-329515-ra20actc	341	5	that	that	DT
cord-329515-ra20actc	341	6	p63	p63	NN
cord-329515-ra20actc	341	7	is	be	VBZ
cord-329515-ra20actc	341	8	stably	stably	RB
cord-329515-ra20actc	341	9	retained	retain	VBN
cord-329515-ra20actc	341	10	between	between	IN
cord-329515-ra20actc	341	11	the	the	DT
cord-329515-ra20actc	341	12	rough	rough	JJ
cord-329515-ra20actc	341	13	ER	er	NN
cord-329515-ra20actc	341	14	and	and	CC
cord-329515-ra20actc	341	15	the	the	DT
cord-329515-ra20actc	341	16	Golgi	Golgi	NNP
cord-329515-ra20actc	341	17	apparatus	apparatus	NN
cord-329515-ra20actc	341	18	(	(	-LRB-
cord-329515-ra20actc	341	19	Schweizer	Schweizer	NNP
cord-329515-ra20actc	341	20	et	et	NNP
cord-329515-ra20actc	341	21	al	al	NNP
cord-329515-ra20actc	341	22	.	.	NNP
cord-329515-ra20actc	341	23	,	,	,
cord-329515-ra20actc	341	24	1993a	1993a	CD
cord-329515-ra20actc	341	25	)	)	-RRB-
cord-329515-ra20actc	341	26	.	.	.
cord-329515-ra20actc	342	1	In	in	IN
cord-329515-ra20actc	342	2	the	the	DT
cord-329515-ra20actc	342	3	present	present	JJ
cord-329515-ra20actc	342	4	study	study	NN
cord-329515-ra20actc	342	5	,	,	,
cord-329515-ra20actc	342	6	we	-PRON-	PRP
cord-329515-ra20actc	342	7	have	have	VBP
cord-329515-ra20actc	342	8	analyzed	analyze	VBN
cord-329515-ra20actc	342	9	the	the	DT
cord-329515-ra20actc	342	10	contribution	contribution	NN
cord-329515-ra20actc	342	11	of	of	IN
cord-329515-ra20actc	342	12	the	the	DT
cord-329515-ra20actc	342	13	individual	individual	JJ
cord-329515-ra20actc	342	14	p63	p63	CD
cord-329515-ra20actc	342	15	domains	domain	NNS
cord-329515-ra20actc	342	16	to	to	IN
cord-329515-ra20actc	342	17	retention	retention	NN
cord-329515-ra20actc	342	18	by	by	IN
cord-329515-ra20actc	342	19	creating	create	VBG
cord-329515-ra20actc	342	20	chimeric	chimeric	JJ
cord-329515-ra20actc	342	21	constructs	construct	NNS
cord-329515-ra20actc	342	22	with	with	IN
cord-329515-ra20actc	342	23	the	the	DT
cord-329515-ra20actc	342	24	type	type	NN
cord-329515-ra20actc	342	25	II	II	NNP
cord-329515-ra20actc	342	26	plasma	plasma	NN
cord-329515-ra20actc	342	27	membrane	membrane	NN
cord-329515-ra20actc	342	28	protein	protein	NN
cord-329515-ra20actc	342	29	DPPIV	DPPIV	NNP
cord-329515-ra20actc	342	30	.	.	.
cord-329515-ra20actc	343	1	The	the	DT
cord-329515-ra20actc	343	2	role	role	NN
cord-329515-ra20actc	343	3	of	of	IN
cord-329515-ra20actc	343	4	the	the	DT
cord-329515-ra20actc	343	5	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	343	6	tail	tail	NN
cord-329515-ra20actc	343	7	was	be	VBD
cord-329515-ra20actc	343	8	further	further	RB
cord-329515-ra20actc	343	9	analyzed	analyze	VBN
cord-329515-ra20actc	343	10	by	by	IN
cord-329515-ra20actc	343	11	deletions	deletion	NNS
cord-329515-ra20actc	343	12	and	and	CC
cord-329515-ra20actc	343	13	point	point	NN
cord-329515-ra20actc	343	14	mutations	mutation	NNS
cord-329515-ra20actc	343	15	within	within	IN
cord-329515-ra20actc	343	16	the	the	DT
cord-329515-ra20actc	343	17	p63	p63	NNP
cord-329515-ra20actc	343	18	protein	protein	NN
cord-329515-ra20actc	343	19	itself	-PRON-	PRP
cord-329515-ra20actc	343	20	.	.	.
cord-329515-ra20actc	344	1	The	the	DT
cord-329515-ra20actc	344	2	appearance	appearance	NN
cord-329515-ra20actc	344	3	of	of	IN
cord-329515-ra20actc	344	4	mutant	mutant	JJ
cord-329515-ra20actc	344	5	p63	p63	CD
cord-329515-ra20actc	344	6	proteins	protein	NNS
cord-329515-ra20actc	344	7	at	at	IN
cord-329515-ra20actc	344	8	the	the	DT
cord-329515-ra20actc	344	9	cell	cell	NN
cord-329515-ra20actc	344	10	surface	surface	NN
cord-329515-ra20actc	344	11	and	and	CC
cord-329515-ra20actc	344	12	the	the	DT
cord-329515-ra20actc	344	13	concomitant	concomitant	JJ
cord-329515-ra20actc	344	14	loss	loss	NN
cord-329515-ra20actc	344	15	of	of	IN
cord-329515-ra20actc	344	16	the	the	DT
cord-329515-ra20actc	344	17	characteristic	characteristic	JJ
cord-329515-ra20actc	344	18	p63wt	p63wt	CD
cord-329515-ra20actc	344	19	internal	internal	JJ
cord-329515-ra20actc	344	20	staining	staining	NN
cord-329515-ra20actc	344	21	pattern	pattern	NN
cord-329515-ra20actc	344	22	were	be	VBD
cord-329515-ra20actc	344	23	used	use	VBN
cord-329515-ra20actc	344	24	as	as	IN
cord-329515-ra20actc	344	25	criteria	criterion	NNS
cord-329515-ra20actc	344	26	for	for	IN
cord-329515-ra20actc	344	27	loss	loss	NN
cord-329515-ra20actc	344	28	of	of	IN
cord-329515-ra20actc	344	29	proper	proper	JJ
cord-329515-ra20actc	344	30	retention	retention	NN
cord-329515-ra20actc	344	31	.	.	.
cord-329515-ra20actc	345	1	Using	use	VBG
cord-329515-ra20actc	345	2	these	these	DT
cord-329515-ra20actc	345	3	approaches	approach	NNS
cord-329515-ra20actc	345	4	,	,	,
cord-329515-ra20actc	345	5	we	-PRON-	PRP
cord-329515-ra20actc	345	6	have	have	VBP
cord-329515-ra20actc	345	7	identiffed	identiffe	VBN
cord-329515-ra20actc	345	8	the	the	DT
cord-329515-ra20actc	345	9	domains	domain	NNS
cord-329515-ra20actc	345	10	of	of	IN
cord-329515-ra20actc	345	11	p63	p63	CD
cord-329515-ra20actc	345	12	that	that	WDT
cord-329515-ra20actc	345	13	determine	determine	VBP
cord-329515-ra20actc	345	14	retention	retention	NN
cord-329515-ra20actc	345	15	and	and	CC
cord-329515-ra20actc	345	16	obtained	obtain	VBN
cord-329515-ra20actc	345	17	data	datum	NNS
cord-329515-ra20actc	345	18	that	that	WDT
cord-329515-ra20actc	345	19	are	be	VBP
cord-329515-ra20actc	345	20	consistent	consistent	JJ
cord-329515-ra20actc	345	21	with	with	IN
cord-329515-ra20actc	345	22	the	the	DT
cord-329515-ra20actc	345	23	notion	notion	NN
cord-329515-ra20actc	345	24	that	that	IN
cord-329515-ra20actc	345	25	oligomerization	oligomerization	NN
cord-329515-ra20actc	345	26	of	of	IN
cord-329515-ra20actc	345	27	p63	p63	CD
cord-329515-ra20actc	345	28	serves	serve	VBZ
cord-329515-ra20actc	345	29	as	as	IN
cord-329515-ra20actc	345	30	a	a	DT
cord-329515-ra20actc	345	31	major	major	JJ
cord-329515-ra20actc	345	32	retention	retention	NN
cord-329515-ra20actc	345	33	mechanism	mechanism	NN
cord-329515-ra20actc	345	34	.	.	.
cord-329515-ra20actc	346	1	Table	table	NN
cord-329515-ra20actc	346	2	I	-PRON-	PRP
cord-329515-ra20actc	346	3	presents	present	VBZ
cord-329515-ra20actc	346	4	a	a	DT
cord-329515-ra20actc	346	5	summary	summary	NN
cord-329515-ra20actc	346	6	of	of	IN
cord-329515-ra20actc	346	7	all	all	PDT
cord-329515-ra20actc	346	8	the	the	DT
cord-329515-ra20actc	346	9	constructs	construct	NNS
cord-329515-ra20actc	346	10	analyzed	analyze	VBN
cord-329515-ra20actc	346	11	in	in	IN
cord-329515-ra20actc	346	12	this	this	DT
cord-329515-ra20actc	346	13	study	study	NN
cord-329515-ra20actc	346	14	.	.	.
cord-329515-ra20actc	347	1	The	the	DT
cord-329515-ra20actc	347	2	striking	striking	JJ
cord-329515-ra20actc	347	3	characteristic	characteristic	NN
cord-329515-ra20actc	347	4	of	of	IN
cord-329515-ra20actc	347	5	p63	p63	JJ
cord-329515-ra20actc	347	6	retention	retention	NN
cord-329515-ra20actc	347	7	is	be	VBZ
cord-329515-ra20actc	347	8	that	that	IN
cord-329515-ra20actc	347	9	no	no	DT
cord-329515-ra20actc	347	10	single	single	JJ
cord-329515-ra20actc	347	11	topological	topological	JJ
cord-329515-ra20actc	347	12	domain	domain	NN
cord-329515-ra20actc	347	13	is	be	VBZ
cord-329515-ra20actc	347	14	sufficient	sufficient	JJ
cord-329515-ra20actc	347	15	to	to	TO
cord-329515-ra20actc	347	16	specify	specify	VB
cord-329515-ra20actc	347	17	retention	retention	NN
cord-329515-ra20actc	347	18	.	.	.
cord-329515-ra20actc	348	1	Rather	rather	RB
cord-329515-ra20actc	348	2	,	,	,
cord-329515-ra20actc	348	3	all	all	DT
cord-329515-ra20actc	348	4	three	three	CD
cord-329515-ra20actc	348	5	domains	domain	NNS
cord-329515-ra20actc	348	6	are	be	VBP
cord-329515-ra20actc	348	7	required	require	VBN
cord-329515-ra20actc	348	8	to	to	TO
cord-329515-ra20actc	348	9	achieve	achieve	VB
cord-329515-ra20actc	348	10	complete	complete	JJ
cord-329515-ra20actc	348	11	intracellular	intracellular	JJ
cord-329515-ra20actc	348	12	retention	retention	NN
cord-329515-ra20actc	348	13	.	.	.
cord-329515-ra20actc	349	1	The	the	DT
cord-329515-ra20actc	349	2	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	349	3	and	and	CC
cord-329515-ra20actc	349	4	lumenal	lumenal	JJ
cord-329515-ra20actc	349	5	domains	domain	NNS
cord-329515-ra20actc	349	6	of	of	IN
cord-329515-ra20actc	349	7	p63	p63	CD
cord-329515-ra20actc	349	8	are	be	VBP
cord-329515-ra20actc	349	9	most	most	RBS
cord-329515-ra20actc	349	10	important	important	JJ
cord-329515-ra20actc	349	11	for	for	IN
cord-329515-ra20actc	349	12	proper	proper	JJ
cord-329515-ra20actc	349	13	localization	localization	NN
cord-329515-ra20actc	349	14	with	with	IN
cord-329515-ra20actc	349	15	the	the	DT
cord-329515-ra20actc	349	16	transmembrane	transmembrane	NN
cord-329515-ra20actc	349	17	domain	domain	NN
cord-329515-ra20actc	349	18	playing	play	VBG
cord-329515-ra20actc	349	19	a	a	DT
cord-329515-ra20actc	349	20	lesser	less	JJR
cord-329515-ra20actc	349	21	role	role	NN
cord-329515-ra20actc	349	22	in	in	IN
cord-329515-ra20actc	349	23	this	this	DT
cord-329515-ra20actc	349	24	process	process	NN
cord-329515-ra20actc	349	25	.	.	.
cord-329515-ra20actc	350	1	These	these	DT
cord-329515-ra20actc	350	2	findings	finding	NNS
cord-329515-ra20actc	350	3	with	with	IN
cord-329515-ra20actc	350	4	p63	p63	CD
cord-329515-ra20actc	350	5	differ	differ	VBP
cord-329515-ra20actc	350	6	from	from	IN
cord-329515-ra20actc	350	7	those	those	DT
cord-329515-ra20actc	350	8	obtained	obtain	VBN
cord-329515-ra20actc	350	9	with	with	IN
cord-329515-ra20actc	350	10	most	most	JJS
cord-329515-ra20actc	350	11	other	other	JJ
cord-329515-ra20actc	350	12	proteins	protein	NNS
cord-329515-ra20actc	350	13	of	of	IN
cord-329515-ra20actc	350	14	the	the	DT
cord-329515-ra20actc	350	15	early	early	JJ
cord-329515-ra20actc	350	16	secretory	secretory	JJ
cord-329515-ra20actc	350	17	pathway	pathway	NN
cord-329515-ra20actc	350	18	where	where	WRB
cord-329515-ra20actc	350	19	one	one	CD
cord-329515-ra20actc	350	20	domain	domain	NN
cord-329515-ra20actc	350	21	has	have	VBZ
cord-329515-ra20actc	350	22	been	be	VBN
cord-329515-ra20actc	350	23	shown	show	VBN
cord-329515-ra20actc	350	24	to	to	TO
cord-329515-ra20actc	350	25	be	be	VB
cord-329515-ra20actc	350	26	sufficient	sufficient	JJ
cord-329515-ra20actc	350	27	for	for	IN
cord-329515-ra20actc	350	28	retention	retention	NN
cord-329515-ra20actc	350	29	.	.	.
cord-329515-ra20actc	351	1	In	in	IN
cord-329515-ra20actc	351	2	the	the	DT
cord-329515-ra20actc	351	3	case	case	NN
cord-329515-ra20actc	351	4	of	of	IN
cord-329515-ra20actc	351	5	resident	resident	JJ
cord-329515-ra20actc	351	6	lumenal	lumenal	NNP
cord-329515-ra20actc	351	7	ER	ER	NNP
cord-329515-ra20actc	351	8	proteins	protein	NNS
cord-329515-ra20actc	351	9	,	,	,
cord-329515-ra20actc	351	10	the	the	DT
cord-329515-ra20actc	351	11	four	four	CD
cord-329515-ra20actc	351	12	-	-	HYPH
cord-329515-ra20actc	351	13	amino	amino	NN
cord-329515-ra20actc	351	14	acid	acid	NN
cord-329515-ra20actc	351	15	sequence	sequence	NN
cord-329515-ra20actc	351	16	KDEL	KDEL	NNP
cord-329515-ra20actc	351	17	at	at	IN
cord-329515-ra20actc	351	18	the	the	DT
cord-329515-ra20actc	351	19	carboxyl	carboxyl	NN
cord-329515-ra20actc	351	20	terminus	terminus	NN
cord-329515-ra20actc	351	21	serves	serve	VBZ
cord-329515-ra20actc	351	22	as	as	IN
cord-329515-ra20actc	351	23	retrieval	retrieval	NN
cord-329515-ra20actc	351	24	signal	signal	NN
cord-329515-ra20actc	351	25	(	(	-LRB-
cord-329515-ra20actc	351	26	Munro	Munro	NNP
cord-329515-ra20actc	351	27	and	and	CC
cord-329515-ra20actc	351	28	Pelham	Pelham	NNP
cord-329515-ra20actc	351	29	,	,	,
cord-329515-ra20actc	351	30	1987	1987	CD
cord-329515-ra20actc	351	31	;	;	:
cord-329515-ra20actc	351	32	Pelham	Pelham	NNP
cord-329515-ra20actc	351	33	,	,	,
cord-329515-ra20actc	351	34	1989	1989	CD
cord-329515-ra20actc	351	35	Pelham	Pelham	NNP
cord-329515-ra20actc	351	36	,	,	,
cord-329515-ra20actc	351	37	,	,	,
cord-329515-ra20actc	351	38	1990	1990	CD
cord-329515-ra20actc	351	39	.	.	.
cord-329515-ra20actc	352	1	Similarly	similarly	RB
cord-329515-ra20actc	352	2	,	,	,
cord-329515-ra20actc	352	3	KKXX	KKXX	NNP
cord-329515-ra20actc	352	4	/	/	SYM
cord-329515-ra20actc	352	5	KXKXX	KXKXX	NNP
cord-329515-ra20actc	352	6	elements	element	NNS
cord-329515-ra20actc	352	7	at	at	IN
cord-329515-ra20actc	352	8	the	the	DT
cord-329515-ra20actc	352	9	carboxyl	carboxyl	NN
cord-329515-ra20actc	352	10	terminus	terminus	NN
cord-329515-ra20actc	352	11	of	of	IN
cord-329515-ra20actc	352	12	the	the	DT
cord-329515-ra20actc	352	13	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	352	14	domains	domain	NNS
cord-329515-ra20actc	352	15	of	of	IN
cord-329515-ra20actc	352	16	type	type	NN
cord-329515-ra20actc	352	17	I	-PRON-	PRP
cord-329515-ra20actc	352	18	transmembrane	transmembrane	NN
cord-329515-ra20actc	352	19	proteins	protein	NNS
cord-329515-ra20actc	352	20	function	function	VBP
cord-329515-ra20actc	352	21	as	as	IN
cord-329515-ra20actc	352	22	retrieval	retrieval	NN
cord-329515-ra20actc	352	23	signals	signal	NNS
cord-329515-ra20actc	352	24	(	(	-LRB-
cord-329515-ra20actc	352	25	Nilsson	Nilsson	NNP
cord-329515-ra20actc	352	26	et	et	NNP
cord-329515-ra20actc	352	27	al	al	NNP
cord-329515-ra20actc	352	28	.	.	.
cord-329515-ra20actc	353	1	,	,	,
cord-329515-ra20actc	353	2	1989	1989	CD
cord-329515-ra20actc	353	3	;	;	:
cord-329515-ra20actc	353	4	Jackson	Jackson	NNP
cord-329515-ra20actc	353	5	et	et	NNP
cord-329515-ra20actc	353	6	al	al	NNP
cord-329515-ra20actc	353	7	.	.	.
cord-329515-ra20actc	354	1	,	,	,
cord-329515-ra20actc	354	2	1990	1990	CD
cord-329515-ra20actc	355	1	Jackson	Jackson	NNP
cord-329515-ra20actc	355	2	et	et	NNP
cord-329515-ra20actc	355	3	al	al	NNP
cord-329515-ra20actc	355	4	.	.	NNP
cord-329515-ra20actc	355	5	,	,	,
cord-329515-ra20actc	355	6	,	,	,
cord-329515-ra20actc	355	7	1993	1993	CD
cord-329515-ra20actc	355	8	.	.	.
cord-329515-ra20actc	356	1	When	when	WRB
cord-329515-ra20actc	356	2	transplanted	transplant	VBN
cord-329515-ra20actc	356	3	onto	onto	IN
cord-329515-ra20actc	356	4	marker	marker	NN
cord-329515-ra20actc	356	5	proteins	protein	NNS
cord-329515-ra20actc	356	6	,	,	,
cord-329515-ra20actc	356	7	these	these	DT
cord-329515-ra20actc	356	8	sequences	sequence	NNS
cord-329515-ra20actc	356	9	are	be	VBP
cord-329515-ra20actc	356	10	sufficient	sufficient	JJ
cord-329515-ra20actc	356	11	to	to	TO
cord-329515-ra20actc	356	12	cause	cause	VB
cord-329515-ra20actc	356	13	retention	retention	NN
cord-329515-ra20actc	356	14	in	in	IN
cord-329515-ra20actc	356	15	the	the	DT
cord-329515-ra20actc	356	16	ER	er	NN
cord-329515-ra20actc	356	17	.	.	.
cord-329515-ra20actc	357	1	The	the	DT
cord-329515-ra20actc	357	2	carboxyl	carboxyl	NN
cord-329515-ra20actc	357	3	-	-	HYPH
cord-329515-ra20actc	357	4	terminal	terminal	NN
cord-329515-ra20actc	357	5	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	357	6	domain	domain	NN
cord-329515-ra20actc	357	7	of	of	IN
cord-329515-ra20actc	357	8	TGN38	TGN38	NNS
cord-329515-ra20actc	357	9	is	be	VBZ
cord-329515-ra20actc	357	10	also	also	RB
cord-329515-ra20actc	357	11	sufficient	sufficient	JJ
cord-329515-ra20actc	357	12	for	for	IN
cord-329515-ra20actc	357	13	localization	localization	NN
cord-329515-ra20actc	357	14	of	of	IN
cord-329515-ra20actc	357	15	chimeric	chimeric	JJ
cord-329515-ra20actc	357	16	proteins	protein	NNS
cord-329515-ra20actc	357	17	to	to	IN
cord-329515-ra20actc	357	18	the	the	DT
cord-329515-ra20actc	357	19	TGN	TGN	NNP
cord-329515-ra20actc	357	20	(	(	-LRB-
cord-329515-ra20actc	357	21	Bos	Bos	NNP
cord-329515-ra20actc	357	22	et	et	NNP
cord-329515-ra20actc	357	23	al	al	NNP
cord-329515-ra20actc	357	24	.	.	NNP
cord-329515-ra20actc	357	25	,	,	,
cord-329515-ra20actc	357	26	1993	1993	CD
cord-329515-ra20actc	357	27	;	;	:
cord-329515-ra20actc	357	28	Humphrey	Humphrey	NNP
cord-329515-ra20actc	357	29	et	et	NNP
cord-329515-ra20actc	357	30	al	al	NNP
cord-329515-ra20actc	357	31	.	.	NNP
cord-329515-ra20actc	357	32	,	,	,
cord-329515-ra20actc	357	33	1993	1993	CD
cord-329515-ra20actc	357	34	;	;	:
cord-329515-ra20actc	357	35	Wong	Wong	NNP
cord-329515-ra20actc	357	36	and	and	CC
cord-329515-ra20actc	357	37	Hong	Hong	NNP
cord-329515-ra20actc	357	38	,	,	,
cord-329515-ra20actc	357	39	1993	1993	CD
cord-329515-ra20actc	357	40	)	)	-RRB-
cord-329515-ra20actc	357	41	.	.	.
cord-329515-ra20actc	358	1	Other	other	JJ
cord-329515-ra20actc	358	2	Golgi	Golgi	NNP
cord-329515-ra20actc	358	3	proteins	protein	NNS
cord-329515-ra20actc	358	4	are	be	VBP
cord-329515-ra20actc	358	5	localized	localize	VBN
cord-329515-ra20actc	358	6	by	by	IN
cord-329515-ra20actc	358	7	means	mean	NNS
cord-329515-ra20actc	358	8	of	of	IN
cord-329515-ra20actc	358	9	their	-PRON-	PRP$
cord-329515-ra20actc	358	10	transmembrane	transmembrane	NN
cord-329515-ra20actc	358	11	domains	domain	NNS
cord-329515-ra20actc	358	12	(	(	-LRB-
cord-329515-ra20actc	358	13	N	N	NNP
cord-329515-ra20actc	358	14	-	-	HYPH
cord-329515-ra20actc	358	15	acetylglucosaminyltransferase	acetylglucosaminyltransferase	NNP
cord-329515-ra20actc	359	1	I	-PRON-	PRP
cord-329515-ra20actc	359	2	(	(	-LRB-
cord-329515-ra20actc	359	3	Burke	Burke	NNP
cord-329515-ra20actc	359	4	et	et	NNP
cord-329515-ra20actc	359	5	al	al	NNP
cord-329515-ra20actc	359	6	.	.	NNP
cord-329515-ra20actc	359	7	,	,	,
cord-329515-ra20actc	359	8	1992	1992	CD
cord-329515-ra20actc	359	9	;	;	:
cord-329515-ra20actc	359	10	Tang	Tang	NNP
cord-329515-ra20actc	359	11	et	et	NNP
cord-329515-ra20actc	359	12	al	al	NNP
cord-329515-ra20actc	359	13	.	.	NNP
cord-329515-ra20actc	359	14	,	,	,
cord-329515-ra20actc	359	15	1992	1992	CD
cord-329515-ra20actc	359	16	)	)	-RRB-
cord-329515-ra20actc	359	17	,	,	,
cord-329515-ra20actc	359	18	galactosyltransferase	galactosyltransferase	NNP
cord-329515-ra20actc	359	19	(	(	-LRB-
cord-329515-ra20actc	359	20	Nilsson	Nilsson	NNP
cord-329515-ra20actc	359	21	et	et	NNP
cord-329515-ra20actc	359	22	al	al	NNP
cord-329515-ra20actc	359	23	.	.	NNP
cord-329515-ra20actc	359	24	,	,	,
cord-329515-ra20actc	359	25	1991	1991	CD
cord-329515-ra20actc	359	26	;	;	:
cord-329515-ra20actc	359	27	Aoki	Aoki	NNP
cord-329515-ra20actc	359	28	et	et	NNP
cord-329515-ra20actc	359	29	al	al	NNP
cord-329515-ra20actc	359	30	.	.	NNP
cord-329515-ra20actc	359	31	,	,	,
cord-329515-ra20actc	359	32	1992	1992	CD
cord-329515-ra20actc	360	1	;	;	:
cord-329515-ra20actc	360	2	Russo	Russo	NNP
cord-329515-ra20actc	360	3	et	et	NNP
cord-329515-ra20actc	360	4	al	al	NNP
cord-329515-ra20actc	360	5	.	.	NNP
cord-329515-ra20actc	360	6	,	,	,
cord-329515-ra20actc	360	7	1992	1992	CD
cord-329515-ra20actc	360	8	)	)	-RRB-
cord-329515-ra20actc	360	9	,	,	,
cord-329515-ra20actc	360	10	and	and	CC
cord-329515-ra20actc	360	11	the	the	DT
cord-329515-ra20actc	360	12	M	M	NNP
cord-329515-ra20actc	360	13	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	360	14	of	of	IN
cord-329515-ra20actc	360	15	avian	avian	JJ
cord-329515-ra20actc	360	16	coronavirus	coronavirus	NN
cord-329515-ra20actc	360	17	(	(	-LRB-
cord-329515-ra20actc	360	18	Swift	Swift	NNP
cord-329515-ra20actc	360	19	and	and	CC
cord-329515-ra20actc	360	20	Machamer	Machamer	NNP
cord-329515-ra20actc	360	21	,	,	,
cord-329515-ra20actc	360	22	1991	1991	CD
cord-329515-ra20actc	360	23	;	;	:
cord-329515-ra20actc	360	24	Machamer	Machamer	NNP
cord-329515-ra20actc	360	25	et	et	NNP
cord-329515-ra20actc	360	26	al	al	NNP
cord-329515-ra20actc	360	27	.	.	NNP
cord-329515-ra20actc	360	28	,	,	,
cord-329515-ra20actc	360	29	1993	1993	CD
cord-329515-ra20actc	360	30	)	)	-RRB-
cord-329515-ra20actc	360	31	or	or	CC
cord-329515-ra20actc	360	32	in	in	IN
cord-329515-ra20actc	360	33	association	association	NN
cord-329515-ra20actc	360	34	with	with	IN
cord-329515-ra20actc	360	35	the	the	DT
cord-329515-ra20actc	360	36	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	360	37	and	and	CC
cord-329515-ra20actc	360	38	lumenal	lumenal	JJ
cord-329515-ra20actc	360	39	flanking	flanking	NN
cord-329515-ra20actc	360	40	sequences	sequence	NNS
cord-329515-ra20actc	360	41	(	(	-LRB-
cord-329515-ra20actc	360	42	or	or	CC
cord-329515-ra20actc	360	43	2,6-sialyltransferase	2,6-sialyltransferase	CD
cord-329515-ra20actc	360	44	(	(	-LRB-
cord-329515-ra20actc	360	45	Munro	Munro	NNP
cord-329515-ra20actc	360	46	,	,	,
cord-329515-ra20actc	360	47	1991	1991	CD
cord-329515-ra20actc	360	48	;	;	:
cord-329515-ra20actc	360	49	Dahdal	Dahdal	NNP
cord-329515-ra20actc	360	50	and	and	CC
cord-329515-ra20actc	360	51	Colley	Colley	NNP
cord-329515-ra20actc	360	52	,	,	,
cord-329515-ra20actc	360	53	1993	1993	CD
cord-329515-ra20actc	360	54	)	)	-RRB-
cord-329515-ra20actc	360	55	.	.	.
cord-329515-ra20actc	361	1	The	the	DT
cord-329515-ra20actc	361	2	E1	e1	NN
cord-329515-ra20actc	361	3	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	361	4	of	of	IN
cord-329515-ra20actc	361	5	the	the	DT
cord-329515-ra20actc	361	6	mouse	mouse	NN
cord-329515-ra20actc	361	7	coronavirus	coronavirus	NN
cord-329515-ra20actc	361	8	is	be	VBZ
cord-329515-ra20actc	361	9	an	an	DT
cord-329515-ra20actc	361	10	exception	exception	NN
cord-329515-ra20actc	361	11	among	among	IN
cord-329515-ra20actc	361	12	the	the	DT
cord-329515-ra20actc	361	13	proteins	protein	NNS
cord-329515-ra20actc	361	14	localized	localize	VBN
cord-329515-ra20actc	361	15	to	to	IN
cord-329515-ra20actc	361	16	the	the	DT
cord-329515-ra20actc	361	17	Golgi	Golgi	NNP
cord-329515-ra20actc	361	18	apparatus	apparatus	NN
cord-329515-ra20actc	361	19	(	(	-LRB-
cord-329515-ra20actc	361	20	Armstrong	Armstrong	NNP
cord-329515-ra20actc	361	21	and	and	CC
cord-329515-ra20actc	361	22	Patel	Patel	NNP
cord-329515-ra20actc	361	23	,	,	,
cord-329515-ra20actc	361	24	1991	1991	CD
cord-329515-ra20actc	361	25	)	)	-RRB-
cord-329515-ra20actc	361	26	.	.	.
cord-329515-ra20actc	362	1	While	while	IN
cord-329515-ra20actc	362	2	a	a	DT
cord-329515-ra20actc	362	3	short	short	JJ
cord-329515-ra20actc	362	4	deletion	deletion	NN
cord-329515-ra20actc	362	5	in	in	IN
cord-329515-ra20actc	362	6	the	the	DT
cord-329515-ra20actc	362	7	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	362	8	tail	tail	NN
cord-329515-ra20actc	362	9	destroyed	destroy	VBD
cord-329515-ra20actc	362	10	retention	retention	NN
cord-329515-ra20actc	362	11	,	,	,
cord-329515-ra20actc	362	12	the	the	DT
cord-329515-ra20actc	362	13	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	362	14	segmet~	segmet~	NNP
cord-329515-ra20actc	363	1	t	t	NNP
cord-329515-ra20actc	363	2	alone	alone	RB
cord-329515-ra20actc	363	3	was	be	VBD
cord-329515-ra20actc	363	4	not	not	RB
cord-329515-ra20actc	363	5	sufficient	sufficient	JJ
cord-329515-ra20actc	363	6	for	for	IN
cord-329515-ra20actc	363	7	retention	retention	NN
cord-329515-ra20actc	363	8	.	.	.
cord-329515-ra20actc	364	1	Similar	similar	JJ
cord-329515-ra20actc	364	2	to	to	IN
cord-329515-ra20actc	364	3	the	the	DT
cord-329515-ra20actc	364	4	finding	finding	NN
cord-329515-ra20actc	364	5	with	with	IN
cord-329515-ra20actc	364	6	p63	p63	CD
cord-329515-ra20actc	364	7	,	,	,
cord-329515-ra20actc	364	8	most	most	JJS
cord-329515-ra20actc	364	9	of	of	IN
cord-329515-ra20actc	364	10	the	the	DT
cord-329515-ra20actc	364	11	sequence	sequence	NN
cord-329515-ra20actc	364	12	appeared	appear	VBD
cord-329515-ra20actc	364	13	to	to	TO
cord-329515-ra20actc	364	14	be	be	VB
cord-329515-ra20actc	364	15	required	require	VBN
cord-329515-ra20actc	364	16	for	for	IN
cord-329515-ra20actc	364	17	proper	proper	JJ
cord-329515-ra20actc	364	18	localization	localization	NN
cord-329515-ra20actc	364	19	.	.	.
cord-329515-ra20actc	365	1	Molecular	molecular	JJ
cord-329515-ra20actc	365	2	dissection	dissection	NN
cord-329515-ra20actc	365	3	of	of	IN
cord-329515-ra20actc	365	4	the	the	DT
cord-329515-ra20actc	365	5	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	365	6	tail	tail	NN
cord-329515-ra20actc	365	7	of	of	IN
cord-329515-ra20actc	365	8	p63	p63	NNP
cord-329515-ra20actc	365	9	identiffed	identiffed	NNP
cord-329515-ra20actc	365	10	the	the	DT
cord-329515-ra20actc	365	11	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	365	12	23	23	CD
cord-329515-ra20actc	365	13	amino	amino	NN
cord-329515-ra20actc	365	14	acids	acid	NNS
cord-329515-ra20actc	365	15	as	as	IN
cord-329515-ra20actc	365	16	being	be	VBG
cord-329515-ra20actc	365	17	necessary	necessary	JJ
cord-329515-ra20actc	365	18	for	for	IN
cord-329515-ra20actc	365	19	retention	retention	NN
cord-329515-ra20actc	366	1	whereas	whereas	IN
cord-329515-ra20actc	366	2	amirio	amirio	NNP
cord-329515-ra20actc	366	3	acids	acid	NNS
cord-329515-ra20actc	366	4	24	24	CD
cord-329515-ra20actc	366	5	-	-	SYM
cord-329515-ra20actc	366	6	100	100	CD
cord-329515-ra20actc	366	7	were	be	VBD
cord-329515-ra20actc	366	8	dispensable	dispensable	JJ
cord-329515-ra20actc	366	9	for	for	IN
cord-329515-ra20actc	366	10	this	this	DT
cord-329515-ra20actc	366	11	function	function	NN
cord-329515-ra20actc	366	12	.	.	.
cord-329515-ra20actc	367	1	Within	within	IN
cord-329515-ra20actc	367	2	the	the	DT
cord-329515-ra20actc	367	3	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	367	4	sequence	sequence	NN
cord-329515-ra20actc	367	5	,	,	,
cord-329515-ra20actc	367	6	substitution	substitution	NN
cord-329515-ra20actc	367	7	of	of	IN
cord-329515-ra20actc	367	8	three	three	CD
cord-329515-ra20actc	367	9	pairs	pair	NNS
cord-329515-ra20actc	367	10	of	of	IN
cord-329515-ra20actc	367	11	amino	amino	NN
cord-329515-ra20actc	367	12	acids	acid	NNS
cord-329515-ra20actc	367	13	each	each	DT
cord-329515-ra20actc	367	14	consisting	consist	VBG
cord-329515-ra20actc	367	15	of	of	IN
cord-329515-ra20actc	367	16	a	a	DT
cord-329515-ra20actc	367	17	positively	positively	RB
cord-329515-ra20actc	367	18	charged	charge	VBN
cord-329515-ra20actc	367	19	amino	amino	NN
cord-329515-ra20actc	367	20	acid	acid	NN
cord-329515-ra20actc	367	21	followed	follow	VBN
cord-329515-ra20actc	367	22	by	by	IN
cord-329515-ra20actc	367	23	a	a	DT
cord-329515-ra20actc	367	24	glycine	glycine	NN
cord-329515-ra20actc	367	25	residue	residue	NN
cord-329515-ra20actc	367	26	~	~	NFP
cord-329515-ra20actc	367	27	Very	very	RB
cord-329515-ra20actc	367	28	rarely	rarely	RB
cord-329515-ra20actc	367	29	a	a	DT
cord-329515-ra20actc	367	30	cell	cell	NN
cord-329515-ra20actc	367	31	showed	show	VBD
cord-329515-ra20actc	367	32	a	a	DT
cord-329515-ra20actc	367	33	p63wt	p63wt	CD
cord-329515-ra20actc	367	34	-	-	HYPH
cord-329515-ra20actc	367	35	related	relate	VBN
cord-329515-ra20actc	367	36	staining	staining	NN
cord-329515-ra20actc	367	37	pattern	pattern	NN
cord-329515-ra20actc	367	38	.	.	.
cord-329515-ra20actc	368	1	The	the	DT
cord-329515-ra20actc	368	2	intensity	intensity	NN
cord-329515-ra20actc	368	3	of	of	IN
cord-329515-ra20actc	368	4	this	this	DT
cord-329515-ra20actc	368	5	cell	cell	NN
cord-329515-ra20actc	368	6	surface	surface	NN
cord-329515-ra20actc	368	7	staining	staining	NN
cord-329515-ra20actc	368	8	was	be	VBD
cord-329515-ra20actc	368	9	fainter	faint	JJR
cord-329515-ra20actc	368	10	than	than	IN
cord-329515-ra20actc	368	11	that	that	DT
cord-329515-ra20actc	368	12	of	of	IN
cord-329515-ra20actc	368	13	DPPIVwt	DPPIVwt	NNP
cord-329515-ra20actc	368	14	or	or	CC
cord-329515-ra20actc	368	15	other	other	JJ
cord-329515-ra20actc	368	16	chimeric	chimeric	JJ
cord-329515-ra20actc	368	17	constructs	construct	NNS
cord-329515-ra20actc	368	18	.	.	.
cord-329515-ra20actc	369	1	(	(	-LRB-
cord-329515-ra20actc	369	2	R	R	NNP
cord-329515-ra20actc	369	3	7	7	CD
cord-329515-ra20actc	369	4	,	,	,
cord-329515-ra20actc	369	5	C	C	NNP
cord-329515-ra20actc	369	6	-s	-s	NN
cord-329515-ra20actc	369	7	,	,	,
cord-329515-ra20actc	369	8	K	K	NNP
cord-329515-ra20actc	369	9	~	~	NNP
cord-329515-ra20actc	369	10	°	°	NNS
cord-329515-ra20actc	369	11	,	,	,
cord-329515-ra20actc	369	12	G	G	NNP
cord-329515-ra20actc	369	13	It	-PRON-	PRP
cord-329515-ra20actc	369	14	,	,	,
cord-329515-ra20actc	369	15	K	K	NNP
cord-329515-ra20actc	369	16	2~	2~	CD
cord-329515-ra20actc	369	17	,	,	,
cord-329515-ra20actc	369	18	and	and	CC
cord-329515-ra20actc	369	19	G	G	NNP
cord-329515-ra20actc	369	20	22	22	CD
cord-329515-ra20actc	369	21	)	)	-RRB-
cord-329515-ra20actc	369	22	by	by	IN
cord-329515-ra20actc	369	23	alanines	alanines	NNP
cord-329515-ra20actc	369	24	(	(	-LRB-
cord-329515-ra20actc	369	25	MP4	MP4	NNP
cord-329515-ra20actc	369	26	)	)	-RRB-
cord-329515-ra20actc	369	27	resulted	result	VBD
cord-329515-ra20actc	369	28	in	in	IN
cord-329515-ra20actc	369	29	transport	transport	NN
cord-329515-ra20actc	369	30	of	of	IN
cord-329515-ra20actc	369	31	the	the	DT
cord-329515-ra20actc	369	32	mutant	mutant	JJ
cord-329515-ra20actc	369	33	protein	protein	NN
cord-329515-ra20actc	369	34	to	to	IN
cord-329515-ra20actc	369	35	the	the	DT
cord-329515-ra20actc	369	36	plasma	plasma	NN
cord-329515-ra20actc	369	37	membrane	membrane	NN
cord-329515-ra20actc	369	38	,	,	,
cord-329515-ra20actc	369	39	indicating	indicate	VBG
cord-329515-ra20actc	369	40	the	the	DT
cord-329515-ra20actc	369	41	importance	importance	NN
cord-329515-ra20actc	369	42	of	of	IN
cord-329515-ra20actc	369	43	the	the	DT
cord-329515-ra20actc	369	44	corresponding	correspond	VBG
cord-329515-ra20actc	369	45	amino	amino	NN
cord-329515-ra20actc	369	46	acids	acid	NNS
cord-329515-ra20actc	369	47	for	for	IN
cord-329515-ra20actc	369	48	correct	correct	JJ
cord-329515-ra20actc	369	49	localization	localization	NN
cord-329515-ra20actc	369	50	of	of	IN
cord-329515-ra20actc	369	51	p63	p63	CD
cord-329515-ra20actc	369	52	.	.	.
cord-329515-ra20actc	370	1	Interestingly	interestingly	RB
cord-329515-ra20actc	370	2	,	,	,
cord-329515-ra20actc	370	3	changing	change	VBG
cord-329515-ra20actc	370	4	either	either	CC
cord-329515-ra20actc	370	5	the	the	DT
cord-329515-ra20actc	370	6	positively	positively	RB
cord-329515-ra20actc	370	7	charged	charge	VBN
cord-329515-ra20actc	370	8	residues	residue	NNS
cord-329515-ra20actc	370	9	or	or	CC
cord-329515-ra20actc	370	10	the	the	DT
cord-329515-ra20actc	370	11	glycines	glycine	NNS
cord-329515-ra20actc	370	12	alone	alone	RB
cord-329515-ra20actc	370	13	(	(	-LRB-
cord-329515-ra20actc	370	14	MP2	MP2	NNP
cord-329515-ra20actc	370	15	,	,	,
cord-329515-ra20actc	370	16	MP3	mp3	NN
cord-329515-ra20actc	370	17	)	)	-RRB-
cord-329515-ra20actc	370	18	did	do	VBD
cord-329515-ra20actc	370	19	not	not	RB
cord-329515-ra20actc	370	20	affect	affect	VB
cord-329515-ra20actc	370	21	retention	retention	NN
cord-329515-ra20actc	370	22	of	of	IN
cord-329515-ra20actc	370	23	p63	p63	CD
cord-329515-ra20actc	370	24	.	.	.
cord-329515-ra20actc	371	1	Further	further	RB
cord-329515-ra20actc	371	2	,	,	,
cord-329515-ra20actc	371	3	the	the	DT
cord-329515-ra20actc	371	4	dements	dement	NNS
cord-329515-ra20actc	371	5	required	require	VBN
cord-329515-ra20actc	371	6	for	for	IN
cord-329515-ra20actc	371	7	retention	retention	NN
cord-329515-ra20actc	371	8	appear	appear	VBP
cord-329515-ra20actc	371	9	to	to	TO
cord-329515-ra20actc	371	10	be	be	VB
cord-329515-ra20actc	371	11	at	at	IN
cord-329515-ra20actc	371	12	least	least	JJS
cord-329515-ra20actc	371	13	partly	partly	RB
cord-329515-ra20actc	371	14	redundant	redundant	JJ
cord-329515-ra20actc	371	15	as	as	IN
cord-329515-ra20actc	371	16	revealed	reveal	VBN
cord-329515-ra20actc	371	17	by	by	IN
cord-329515-ra20actc	371	18	the	the	DT
cord-329515-ra20actc	371	19	analysis	analysis	NN
cord-329515-ra20actc	371	20	of	of	IN
cord-329515-ra20actc	371	21	the	the	DT
cord-329515-ra20actc	371	22	overlapping	overlap	VBG
cord-329515-ra20actc	371	23	alanine	alanine	NN
cord-329515-ra20actc	371	24	scan	scan	NN
cord-329515-ra20actc	371	25	of	of	IN
cord-329515-ra20actc	371	26	A24	A24	NNP
cord-329515-ra20actc	371	27	-	-	HYPH
cord-329515-ra20actc	371	28	101	101	CD
cord-329515-ra20actc	371	29	,	,	,
cord-329515-ra20actc	371	30	a	a	DT
cord-329515-ra20actc	371	31	similar	similar	JJ
cord-329515-ra20actc	371	32	scan	scan	NN
cord-329515-ra20actc	371	33	of	of	IN
cord-329515-ra20actc	371	34	AI6	AI6	NNP
cord-329515-ra20actc	371	35	-	-	HYPH
cord-329515-ra20actc	371	36	101	101	CD
cord-329515-ra20actc	371	37	,	,	,
cord-329515-ra20actc	371	38	and	and	CC
cord-329515-ra20actc	371	39	the	the	DT
cord-329515-ra20actc	371	40	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	371	41	tail	tail	NN
cord-329515-ra20actc	371	42	deletion	deletion	NN
cord-329515-ra20actc	371	43	mutants	mutant	NNS
cord-329515-ra20actc	371	44	.	.	.
cord-329515-ra20actc	372	1	What	what	WP
cord-329515-ra20actc	372	2	is	be	VBZ
cord-329515-ra20actc	372	3	the	the	DT
cord-329515-ra20actc	372	4	role	role	NN
cord-329515-ra20actc	372	5	of	of	IN
cord-329515-ra20actc	372	6	the	the	DT
cord-329515-ra20actc	372	7	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	372	8	tail	tail	NN
cord-329515-ra20actc	372	9	in	in	IN
cord-329515-ra20actc	372	10	conferring	confer	VBG
cord-329515-ra20actc	372	11	proper	proper	JJ
cord-329515-ra20actc	372	12	intracellular	intracellular	JJ
cord-329515-ra20actc	372	13	retention	retention	NN
cord-329515-ra20actc	372	14	of	of	IN
cord-329515-ra20actc	372	15	p63	p63	CD
cord-329515-ra20actc	372	16	?	?	.
cord-329515-ra20actc	373	1	A	a	DT
cord-329515-ra20actc	373	2	potential	potential	JJ
cord-329515-ra20actc	373	3	clue	clue	NN
cord-329515-ra20actc	373	4	emerged	emerge	VBD
cord-329515-ra20actc	373	5	when	when	WRB
cord-329515-ra20actc	373	6	we	-PRON-	PRP
cord-329515-ra20actc	373	7	analyzed	analyze	VBD
cord-329515-ra20actc	373	8	the	the	DT
cord-329515-ra20actc	373	9	solubility	solubility	NN
cord-329515-ra20actc	373	10	of	of	IN
cord-329515-ra20actc	373	11	the	the	DT
cord-329515-ra20actc	373	12	various	various	JJ
cord-329515-ra20actc	373	13	constructs	construct	NNS
cord-329515-ra20actc	373	14	in	in	IN
cord-329515-ra20actc	373	15	the	the	DT
cord-329515-ra20actc	373	16	nonionic	nonionic	NNP
cord-329515-ra20actc	373	17	detergent	detergent	NN
cord-329515-ra20actc	373	18	Triton	Triton	NNP
cord-329515-ra20actc	373	19	X-100	x-100	RB
cord-329515-ra20actc	373	20	.	.	.
cord-329515-ra20actc	374	1	When	when	WRB
cord-329515-ra20actc	374	2	transfected	transfecte	VBN
cord-329515-ra20actc	374	3	cells	cell	NNS
cord-329515-ra20actc	374	4	were	be	VBD
cord-329515-ra20actc	374	5	solubilized	solubilize	VBN
cord-329515-ra20actc	374	6	with	with	IN
cord-329515-ra20actc	374	7	Triton	Triton	NNP
cord-329515-ra20actc	374	8	X-100	x-100	RB
cord-329515-ra20actc	374	9	at	at	IN
cord-329515-ra20actc	374	10	pH	pH	NNP
cord-329515-ra20actc	374	11	6.5	6.5	CD
cord-329515-ra20actc	374	12	and	and	CC
cord-329515-ra20actc	374	13	then	then	RB
cord-329515-ra20actc	374	14	subjected	subject	VBN
cord-329515-ra20actc	374	15	to	to	IN
cord-329515-ra20actc	374	16	ultracentrifugation	ultracentrifugation	NN
cord-329515-ra20actc	374	17	at	at	IN
cord-329515-ra20actc	374	18	100,000	100,000	CD
cord-329515-ra20actc	374	19	g	g	NN
cord-329515-ra20actc	374	20	,	,	,
cord-329515-ra20actc	374	21	the	the	DT
cord-329515-ra20actc	374	22	proteins	protein	NNS
cord-329515-ra20actc	374	23	that	that	WDT
cord-329515-ra20actc	374	24	were	be	VBD
cord-329515-ra20actc	374	25	properly	properly	RB
cord-329515-ra20actc	374	26	retained	retain	VBN
cord-329515-ra20actc	374	27	(	(	-LRB-
cord-329515-ra20actc	374	28	p63wt	p63wt	XX
cord-329515-ra20actc	374	29	,	,	,
cord-329515-ra20actc	374	30	A24	A24	NNP
cord-329515-ra20actc	374	31	-	-	HYPH
cord-329515-ra20actc	374	32	101	101	CD
cord-329515-ra20actc	374	33	,	,	,
cord-329515-ra20actc	374	34	MP2	MP2	NNP
cord-329515-ra20actc	374	35	,	,	,
cord-329515-ra20actc	374	36	and	and	CC
cord-329515-ra20actc	374	37	MP3	mp3	NN
cord-329515-ra20actc	374	38	)	)	-RRB-
cord-329515-ra20actc	374	39	were	be	VBD
cord-329515-ra20actc	374	40	predominantly	predominantly	RB
cord-329515-ra20actc	374	41	found	find	VBN
cord-329515-ra20actc	374	42	in	in	IN
cord-329515-ra20actc	374	43	the	the	DT
cord-329515-ra20actc	374	44	pellet	pellet	NN
cord-329515-ra20actc	374	45	fraction	fraction	NN
cord-329515-ra20actc	374	46	whereas	whereas	IN
cord-329515-ra20actc	374	47	the	the	DT
cord-329515-ra20actc	374	48	nonretained	nonretained	JJ
cord-329515-ra20actc	374	49	proteins	protein	NNS
cord-329515-ra20actc	374	50	(	(	-LRB-
cord-329515-ra20actc	374	51	A2	A2	NNP
cord-329515-ra20actc	374	52	-	-	HYPH
cord-329515-ra20actc	374	53	101AA	101AA	NNP
cord-329515-ra20actc	374	54	and	and	CC
cord-329515-ra20actc	374	55	MP1	MP1	NNP
cord-329515-ra20actc	374	56	)	)	-RRB-
cord-329515-ra20actc	374	57	were	be	VBD
cord-329515-ra20actc	374	58	mostly	mostly	RB
cord-329515-ra20actc	374	59	recovered	recover	VBN
cord-329515-ra20actc	374	60	in	in	IN
cord-329515-ra20actc	374	61	the	the	DT
cord-329515-ra20actc	374	62	supernatant	supernatant	NN
cord-329515-ra20actc	374	63	.	.	.
cord-329515-ra20actc	375	1	Endogenous	endogenous	JJ
cord-329515-ra20actc	375	2	p63	p63	NNS
cord-329515-ra20actc	375	3	from	from	IN
cord-329515-ra20actc	375	4	COS	COS	NNP
cord-329515-ra20actc	375	5	cells	cell	NNS
cord-329515-ra20actc	375	6	was	be	VBD
cord-329515-ra20actc	375	7	exclusively	exclusively	RB
cord-329515-ra20actc	375	8	found	find	VBN
cord-329515-ra20actc	375	9	in	in	IN
cord-329515-ra20actc	375	10	the	the	DT
cord-329515-ra20actc	375	11	100,000	100,000	CD
cord-329515-ra20actc	375	12	g	g	NN
cord-329515-ra20actc	375	13	pellet	pellet	NN
cord-329515-ra20actc	375	14	,	,	,
cord-329515-ra20actc	375	15	demonstrating	demonstrate	VBG
cord-329515-ra20actc	375	16	that	that	IN
cord-329515-ra20actc	375	17	the	the	DT
cord-329515-ra20actc	375	18	property	property	NN
cord-329515-ra20actc	375	19	is	be	VBZ
cord-329515-ra20actc	375	20	not	not	RB
cord-329515-ra20actc	375	21	a	a	DT
cord-329515-ra20actc	375	22	function	function	NN
cord-329515-ra20actc	375	23	of	of	IN
cord-329515-ra20actc	375	24	transfection	transfection	NN
cord-329515-ra20actc	375	25	and/or	and/or	CC
cord-329515-ra20actc	375	26	overexpression	overexpression	NN
cord-329515-ra20actc	375	27	.	.	.
cord-329515-ra20actc	376	1	While	while	IN
cord-329515-ra20actc	376	2	the	the	DT
cord-329515-ra20actc	376	3	extent	extent	NN
cord-329515-ra20actc	376	4	of	of	IN
cord-329515-ra20actc	376	5	Triton	Triton	NNP
cord-329515-ra20actc	376	6	X-100-insolubility	x-100-insolubility	NN
cord-329515-ra20actc	376	7	of	of	IN
cord-329515-ra20actc	376	8	p63wt	p63wt	NNP
cord-329515-ra20actc	376	9	increased	increase	VBD
cord-329515-ra20actc	376	10	with	with	IN
cord-329515-ra20actc	376	11	decreasing	decrease	VBG
cord-329515-ra20actc	376	12	pH	ph	NN
cord-329515-ra20actc	376	13	,	,	,
cord-329515-ra20actc	376	14	most	most	JJS
cord-329515-ra20actc	376	15	of	of	IN
cord-329515-ra20actc	376	16	the	the	DT
cord-329515-ra20actc	376	17	protein	protein	NN
cord-329515-ra20actc	376	18	was	be	VBD
cord-329515-ra20actc	376	19	insoluble	insoluble	JJ
cord-329515-ra20actc	376	20	at	at	IN
cord-329515-ra20actc	376	21	pH	pH	NNP
cord-329515-ra20actc	376	22	7.4	7.4	CD
cord-329515-ra20actc	376	23	,	,	,
cord-329515-ra20actc	376	24	which	which	WDT
cord-329515-ra20actc	376	25	is	be	VBZ
cord-329515-ra20actc	376	26	similar	similar	JJ
cord-329515-ra20actc	376	27	to	to	IN
cord-329515-ra20actc	376	28	the	the	DT
cord-329515-ra20actc	376	29	pH	ph	NN
cord-329515-ra20actc	376	30	of	of	IN
cord-329515-ra20actc	376	31	the	the	DT
cord-329515-ra20actc	376	32	cytoplasm	cytoplasm	NN
cord-329515-ra20actc	376	33	.	.	.
cord-329515-ra20actc	377	1	Since	since	IN
cord-329515-ra20actc	377	2	highly	highly	RB
cord-329515-ra20actc	377	3	purified	purify	VBN
cord-329515-ra20actc	377	4	p63wt	p63wt	XX
cord-329515-ra20actc	377	5	exhibited	exhibit	VBD
cord-329515-ra20actc	377	6	the	the	DT
cord-329515-ra20actc	377	7	same	same	JJ
cord-329515-ra20actc	377	8	pHdependent	pHdependent	NNP
cord-329515-ra20actc	377	9	insolubility	insolubility	NN
cord-329515-ra20actc	377	10	in	in	IN
cord-329515-ra20actc	377	11	Triton	Triton	NNP
cord-329515-ra20actc	377	12	X-100	x-100	NN
cord-329515-ra20actc	377	13	,	,	,
cord-329515-ra20actc	377	14	we	-PRON-	PRP
cord-329515-ra20actc	377	15	conclude	conclude	VBP
cord-329515-ra20actc	377	16	that	that	IN
cord-329515-ra20actc	377	17	this	this	DT
cord-329515-ra20actc	377	18	behavior	behavior	NN
cord-329515-ra20actc	377	19	is	be	VBZ
cord-329515-ra20actc	377	20	an	an	DT
cord-329515-ra20actc	377	21	intrinsic	intrinsic	JJ
cord-329515-ra20actc	377	22	property	property	NN
cord-329515-ra20actc	377	23	of	of	IN
cord-329515-ra20actc	377	24	the	the	DT
cord-329515-ra20actc	377	25	protein	protein	NN
cord-329515-ra20actc	377	26	.	.	.
cord-329515-ra20actc	378	1	This	this	DT
cord-329515-ra20actc	378	2	does	do	VBZ
cord-329515-ra20actc	378	3	not	not	RB
cord-329515-ra20actc	378	4	exclude	exclude	VB
cord-329515-ra20actc	378	5	the	the	DT
cord-329515-ra20actc	378	6	possibility	possibility	NN
cord-329515-ra20actc	378	7	that	that	WDT
cord-329515-ra20actc	378	8	p63	p63	VBZ
cord-329515-ra20actc	378	9	also	also	RB
cord-329515-ra20actc	378	10	interacts	interact	VBZ
cord-329515-ra20actc	378	11	with	with	IN
cord-329515-ra20actc	378	12	other	other	JJ
cord-329515-ra20actc	378	13	resi	resi	JJ
cord-329515-ra20actc	378	14	-	-	HYPH
cord-329515-ra20actc	378	15	dent	dent	NN
cord-329515-ra20actc	378	16	proteins	protein	NNS
cord-329515-ra20actc	378	17	of	of	IN
cord-329515-ra20actc	378	18	the	the	DT
cord-329515-ra20actc	378	19	compartment	compartment	NN
cord-329515-ra20actc	378	20	or	or	CC
cord-329515-ra20actc	378	21	with	with	IN
cord-329515-ra20actc	378	22	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	378	23	elements	element	NNS
cord-329515-ra20actc	378	24	,	,	,
cord-329515-ra20actc	378	25	such	such	JJ
cord-329515-ra20actc	378	26	as	as	IN
cord-329515-ra20actc	378	27	members	member	NNS
cord-329515-ra20actc	378	28	of	of	IN
cord-329515-ra20actc	378	29	the	the	DT
cord-329515-ra20actc	378	30	cytoskeleton	cytoskeleton	NN
cord-329515-ra20actc	378	31	.	.	.
cord-329515-ra20actc	379	1	The	the	DT
cord-329515-ra20actc	379	2	striking	striking	JJ
cord-329515-ra20actc	379	3	correlation	correlation	NN
cord-329515-ra20actc	379	4	between	between	IN
cord-329515-ra20actc	379	5	proper	proper	JJ
cord-329515-ra20actc	379	6	intracellular	intracellular	JJ
cord-329515-ra20actc	379	7	localization	localization	NN
cord-329515-ra20actc	379	8	and	and	CC
cord-329515-ra20actc	379	9	Triton	Triton	NNP
cord-329515-ra20actc	379	10	X-100-insolubility	x-100-insolubility	NN
cord-329515-ra20actc	379	11	suggests	suggest	VBZ
cord-329515-ra20actc	379	12	a	a	DT
cord-329515-ra20actc	379	13	retention	retention	NN
cord-329515-ra20actc	379	14	mechanism	mechanism	NN
cord-329515-ra20actc	379	15	for	for	IN
cord-329515-ra20actc	379	16	p63	p63	NN
cord-329515-ra20actc	379	17	that	that	WDT
cord-329515-ra20actc	379	18	involves	involve	VBZ
cord-329515-ra20actc	379	19	homooligomerization	homooligomerization	NN
cord-329515-ra20actc	379	20	.	.	.
cord-329515-ra20actc	380	1	The	the	DT
cord-329515-ra20actc	380	2	model	model	NN
cord-329515-ra20actc	380	3	predicts	predict	VBZ
cord-329515-ra20actc	380	4	that	that	IN
cord-329515-ra20actc	380	5	upon	upon	IN
cord-329515-ra20actc	380	6	arrival	arrival	NN
cord-329515-ra20actc	380	7	at	at	IN
cord-329515-ra20actc	380	8	their	-PRON-	PRP$
cord-329515-ra20actc	380	9	final	final	JJ
cord-329515-ra20actc	380	10	destination	destination	NN
cord-329515-ra20actc	380	11	,	,	,
cord-329515-ra20actc	380	12	p63	p63	NN
cord-329515-ra20actc	380	13	molecules	molecule	NNS
cord-329515-ra20actc	380	14	encounter	encounter	VBP
cord-329515-ra20actc	380	15	an	an	DT
cord-329515-ra20actc	380	16	environment	environment	NN
cord-329515-ra20actc	380	17	that	that	WDT
cord-329515-ra20actc	380	18	leads	lead	VBZ
cord-329515-ra20actc	380	19	to	to	IN
cord-329515-ra20actc	380	20	self	self	NN
cord-329515-ra20actc	380	21	aggregation	aggregation	NN
cord-329515-ra20actc	380	22	resulting	result	VBG
cord-329515-ra20actc	380	23	in	in	IN
cord-329515-ra20actc	380	24	the	the	DT
cord-329515-ra20actc	380	25	formation	formation	NN
cord-329515-ra20actc	380	26	of	of	IN
cord-329515-ra20actc	380	27	large	large	JJ
cord-329515-ra20actc	380	28	oligomers	oligomer	NNS
cord-329515-ra20actc	380	29	.	.	.
cord-329515-ra20actc	381	1	The	the	DT
cord-329515-ra20actc	381	2	specific	specific	JJ
cord-329515-ra20actc	381	3	conditions	condition	NNS
cord-329515-ra20actc	381	4	that	that	WDT
cord-329515-ra20actc	381	5	might	may	MD
cord-329515-ra20actc	381	6	trigger	trigger	VB
cord-329515-ra20actc	381	7	the	the	DT
cord-329515-ra20actc	381	8	oligomerization	oligomerization	NN
cord-329515-ra20actc	381	9	of	of	IN
cord-329515-ra20actc	381	10	p63	p63	CD
cord-329515-ra20actc	381	11	are	be	VBP
cord-329515-ra20actc	381	12	unknown	unknown	JJ
cord-329515-ra20actc	381	13	,	,	,
cord-329515-ra20actc	381	14	but	but	CC
cord-329515-ra20actc	381	15	could	could	MD
cord-329515-ra20actc	381	16	include	include	VB
cord-329515-ra20actc	381	17	differences	difference	NNS
cord-329515-ra20actc	381	18	in	in	IN
cord-329515-ra20actc	381	19	ion	ion	NN
cord-329515-ra20actc	381	20	composition	composition	NN
cord-329515-ra20actc	381	21	,	,	,
cord-329515-ra20actc	381	22	lumenal	lumenal	NNP
cord-329515-ra20actc	381	23	pH	ph	NN
cord-329515-ra20actc	381	24	or	or	CC
cord-329515-ra20actc	381	25	properties	property	NNS
cord-329515-ra20actc	381	26	of	of	IN
cord-329515-ra20actc	381	27	the	the	DT
cord-329515-ra20actc	381	28	local	local	JJ
cord-329515-ra20actc	381	29	membrane	membrane	NN
cord-329515-ra20actc	381	30	.	.	.
cord-329515-ra20actc	382	1	This	this	DT
cord-329515-ra20actc	382	2	proposed	propose	VBN
cord-329515-ra20actc	382	3	retention	retention	NN
cord-329515-ra20actc	382	4	mechanism	mechanism	NN
cord-329515-ra20actc	382	5	is	be	VBZ
cord-329515-ra20actc	382	6	compatible	compatible	JJ
cord-329515-ra20actc	382	7	with	with	IN
cord-329515-ra20actc	382	8	several	several	JJ
cord-329515-ra20actc	382	9	additional	additional	JJ
cord-329515-ra20actc	382	10	findings	finding	NNS
cord-329515-ra20actc	382	11	.	.	.
cord-329515-ra20actc	383	1	First	first	RB
cord-329515-ra20actc	383	2	,	,	,
cord-329515-ra20actc	383	3	high	high	JJ
cord-329515-ra20actc	383	4	levels	level	NNS
cord-329515-ra20actc	383	5	of	of	IN
cord-329515-ra20actc	383	6	expression	expression	NN
cord-329515-ra20actc	383	7	do	do	VBP
cord-329515-ra20actc	383	8	not	not	RB
cord-329515-ra20actc	383	9	result	result	VB
cord-329515-ra20actc	383	10	in	in	IN
cord-329515-ra20actc	383	11	mislocalization	mislocalization	NN
cord-329515-ra20actc	383	12	of	of	IN
cord-329515-ra20actc	383	13	p63	p63	CD
cord-329515-ra20actc	383	14	to	to	IN
cord-329515-ra20actc	383	15	the	the	DT
cord-329515-ra20actc	383	16	plasma	plasma	NN
cord-329515-ra20actc	383	17	membrane	membrane	NN
cord-329515-ra20actc	383	18	,	,	,
cord-329515-ra20actc	383	19	indicating	indicate	VBG
cord-329515-ra20actc	383	20	that	that	IN
cord-329515-ra20actc	383	21	the	the	DT
cord-329515-ra20actc	383	22	p63	p63	CD
cord-329515-ra20actc	383	23	retention	retention	NN
cord-329515-ra20actc	383	24	system	system	NN
cord-329515-ra20actc	383	25	is	be	VBZ
cord-329515-ra20actc	383	26	not	not	RB
cord-329515-ra20actc	383	27	saturable	saturable	JJ
cord-329515-ra20actc	383	28	.	.	.
cord-329515-ra20actc	384	1	If	if	IN
cord-329515-ra20actc	384	2	p63	p63	CD
cord-329515-ra20actc	384	3	interacted	interact	VBN
cord-329515-ra20actc	384	4	with	with	IN
cord-329515-ra20actc	384	5	a	a	DT
cord-329515-ra20actc	384	6	specific	specific	JJ
cord-329515-ra20actc	384	7	receptor	receptor	NN
cord-329515-ra20actc	384	8	,	,	,
cord-329515-ra20actc	384	9	overexpression	overexpression	NN
cord-329515-ra20actc	384	10	would	would	MD
cord-329515-ra20actc	384	11	likely	likely	RB
cord-329515-ra20actc	384	12	lead	lead	VB
cord-329515-ra20actc	384	13	to	to	IN
cord-329515-ra20actc	384	14	saturation	saturation	NN
cord-329515-ra20actc	384	15	of	of	IN
cord-329515-ra20actc	384	16	the	the	DT
cord-329515-ra20actc	384	17	retention	retention	NN
cord-329515-ra20actc	384	18	machinery	machinery	NN
cord-329515-ra20actc	384	19	and	and	CC
cord-329515-ra20actc	384	20	the	the	DT
cord-329515-ra20actc	384	21	appearance	appearance	NN
cord-329515-ra20actc	384	22	of	of	IN
cord-329515-ra20actc	384	23	the	the	DT
cord-329515-ra20actc	384	24	protein	protein	NN
cord-329515-ra20actc	384	25	at	at	IN
cord-329515-ra20actc	384	26	the	the	DT
cord-329515-ra20actc	384	27	cell	cell	NN
cord-329515-ra20actc	384	28	surface	surface	NN
cord-329515-ra20actc	384	29	.	.	.
cord-329515-ra20actc	385	1	Second	second	RB
cord-329515-ra20actc	385	2	,	,	,
cord-329515-ra20actc	385	3	as	as	IN
cord-329515-ra20actc	385	4	mentioned	mention	VBN
cord-329515-ra20actc	385	5	above	above	RB
cord-329515-ra20actc	385	6	,	,	,
cord-329515-ra20actc	385	7	all	all	DT
cord-329515-ra20actc	385	8	three	three	CD
cord-329515-ra20actc	385	9	domains	domain	NNS
cord-329515-ra20actc	385	10	of	of	IN
cord-329515-ra20actc	385	11	p63	p63	NNS
cord-329515-ra20actc	385	12	are	be	VBP
cord-329515-ra20actc	385	13	necessary	necessary	JJ
cord-329515-ra20actc	385	14	for	for	IN
cord-329515-ra20actc	385	15	complete	complete	JJ
cord-329515-ra20actc	385	16	retention	retention	NN
cord-329515-ra20actc	385	17	,	,	,
cord-329515-ra20actc	385	18	as	as	IN
cord-329515-ra20actc	385	19	would	would	MD
cord-329515-ra20actc	385	20	be	be	VB
cord-329515-ra20actc	385	21	expected	expect	VBN
cord-329515-ra20actc	385	22	if	if	IN
cord-329515-ra20actc	385	23	the	the	DT
cord-329515-ra20actc	385	24	molecule	molecule	NN
cord-329515-ra20actc	385	25	formed	form	VBD
cord-329515-ra20actc	385	26	higher	high	JJR
cord-329515-ra20actc	385	27	order	order	NN
cord-329515-ra20actc	385	28	structures	structure	NNS
cord-329515-ra20actc	385	29	.	.	.
cord-329515-ra20actc	386	1	When	when	WRB
cord-329515-ra20actc	386	2	Triton	Triton	NNP
cord-329515-ra20actc	386	3	X-100-soluble	x-100-soluble	NN
cord-329515-ra20actc	386	4	p63	p63	CD
cord-329515-ra20actc	386	5	molecules	molecule	NNS
cord-329515-ra20actc	386	6	were	be	VBD
cord-329515-ra20actc	386	7	examined	examine	VBN
cord-329515-ra20actc	386	8	by	by	IN
cord-329515-ra20actc	386	9	sucrose	sucrose	NN
cord-329515-ra20actc	386	10	gradient	gradient	NN
cord-329515-ra20actc	386	11	centrifugation	centrifugation	NN
cord-329515-ra20actc	386	12	or	or	CC
cord-329515-ra20actc	386	13	nonreducing	nonreducing	NN
cord-329515-ra20actc	386	14	SDS	SDS	NNP
cord-329515-ra20actc	386	15	-	-	HYPH
cord-329515-ra20actc	386	16	PAGE	PAGE	NNP
cord-329515-ra20actc	386	17	,	,	,
cord-329515-ra20actc	386	18	the	the	DT
cord-329515-ra20actc	386	19	majority	majority	NN
cord-329515-ra20actc	386	20	of	of	IN
cord-329515-ra20actc	386	21	the	the	DT
cord-329515-ra20actc	386	22	molecules	molecule	NNS
cord-329515-ra20actc	386	23	were	be	VBD
cord-329515-ra20actc	386	24	present	present	JJ
cord-329515-ra20actc	386	25	as	as	IN
cord-329515-ra20actc	386	26	noncovalently	noncovalently	RB
cord-329515-ra20actc	386	27	linked	link	VBN
cord-329515-ra20actc	386	28	dimers	dimer	NNS
cord-329515-ra20actc	386	29	(	(	-LRB-
cord-329515-ra20actc	386	30	Schweizer	Schweizer	NNP
cord-329515-ra20actc	386	31	et	et	NNP
cord-329515-ra20actc	386	32	al	al	NNP
cord-329515-ra20actc	386	33	.	.	NNP
cord-329515-ra20actc	386	34	,	,	,
cord-329515-ra20actc	386	35	1993a	1993a	CD
cord-329515-ra20actc	386	36	;	;	:
cord-329515-ra20actc	386	37	Schweizer	Schweizer	NNP
cord-329515-ra20actc	386	38	,	,	,
cord-329515-ra20actc	386	39	A.	A.	NNP
cord-329515-ra20actc	386	40	,	,	,
cord-329515-ra20actc	386	41	J.	J.	NNP
cord-329515-ra20actc	386	42	Rohrer	Rohrer	NNP
cord-329515-ra20actc	386	43	,	,	,
cord-329515-ra20actc	386	44	and	and	CC
cord-329515-ra20actc	386	45	S.	S.	NNP
cord-329515-ra20actc	386	46	Kornfeld	Kornfeld	NNP
cord-329515-ra20actc	386	47	,	,	,
cord-329515-ra20actc	386	48	unpublished	unpublished	JJ
cord-329515-ra20actc	386	49	data	datum	NNS
cord-329515-ra20actc	386	50	)	)	-RRB-
cord-329515-ra20actc	386	51	.	.	.
cord-329515-ra20actc	387	1	Interestingly	interestingly	RB
cord-329515-ra20actc	387	2	,	,	,
cord-329515-ra20actc	387	3	this	this	DT
cord-329515-ra20actc	387	4	dimerization	dimerization	NN
cord-329515-ra20actc	387	5	of	of	IN
cord-329515-ra20actc	387	6	p63	p63	CD
cord-329515-ra20actc	387	7	is	be	VBZ
cord-329515-ra20actc	387	8	independent	independent	JJ
cord-329515-ra20actc	387	9	on	on	IN
cord-329515-ra20actc	387	10	the	the	DT
cord-329515-ra20actc	387	11	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	387	12	tail	tail	NN
cord-329515-ra20actc	387	13	,	,	,
cord-329515-ra20actc	387	14	in	in	IN
cord-329515-ra20actc	387	15	contrast	contrast	NN
cord-329515-ra20actc	387	16	to	to	IN
cord-329515-ra20actc	387	17	the	the	DT
cord-329515-ra20actc	387	18	formation	formation	NN
cord-329515-ra20actc	387	19	of	of	IN
cord-329515-ra20actc	387	20	higher	high	JJR
cord-329515-ra20actc	387	21	oligomeric	oligomeric	JJ
cord-329515-ra20actc	387	22	complexes	complex	NNS
cord-329515-ra20actc	387	23	.	.	.
cord-329515-ra20actc	388	1	Taken	take	VBN
cord-329515-ra20actc	388	2	together	together	RB
cord-329515-ra20actc	388	3	,	,	,
cord-329515-ra20actc	388	4	the	the	DT
cord-329515-ra20actc	388	5	most	most	RBS
cord-329515-ra20actc	388	6	straightforward	straightforward	JJ
cord-329515-ra20actc	388	7	interpretation	interpretation	NN
cord-329515-ra20actc	388	8	of	of	IN
cord-329515-ra20actc	388	9	our	-PRON-	PRP$
cord-329515-ra20actc	388	10	results	result	NNS
cord-329515-ra20actc	388	11	is	be	VBZ
cord-329515-ra20actc	388	12	as	as	IN
cord-329515-ra20actc	388	13	follows	follow	VBZ
cord-329515-ra20actc	388	14	.	.	.
cord-329515-ra20actc	389	1	The	the	DT
cord-329515-ra20actc	389	2	lumenal	lumenal	JJ
cord-329515-ra20actc	389	3	domains	domain	NNS
cord-329515-ra20actc	389	4	of	of	IN
cord-329515-ra20actc	389	5	individual	individual	JJ
cord-329515-ra20actc	389	6	p63	p63	CD
cord-329515-ra20actc	389	7	molecules	molecule	NNS
cord-329515-ra20actc	389	8	interact	interact	VBP
cord-329515-ra20actc	389	9	to	to	TO
cord-329515-ra20actc	389	10	form	form	VB
cord-329515-ra20actc	389	11	noncovalently	noncovalently	RB
cord-329515-ra20actc	389	12	linked	link	VBN
cord-329515-ra20actc	389	13	dimers	dimer	NNS
cord-329515-ra20actc	389	14	,	,	,
cord-329515-ra20actc	389	15	with	with	IN
cord-329515-ra20actc	389	16	the	the	DT
cord-329515-ra20actc	389	17	transmembrane	transmembrane	NN
cord-329515-ra20actc	389	18	domains	domain	NNS
cord-329515-ra20actc	389	19	possibly	possibly	RB
cord-329515-ra20actc	389	20	having	have	VBG
cord-329515-ra20actc	389	21	an	an	DT
cord-329515-ra20actc	389	22	accessory	accessory	JJ
cord-329515-ra20actc	389	23	role	role	NN
cord-329515-ra20actc	389	24	.	.	.
cord-329515-ra20actc	390	1	These	these	DT
cord-329515-ra20actc	390	2	dimers	dimer	NNS
cord-329515-ra20actc	390	3	would	would	MD
cord-329515-ra20actc	390	4	represent	represent	VB
cord-329515-ra20actc	390	5	the	the	DT
cord-329515-ra20actc	390	6	basic	basic	JJ
cord-329515-ra20actc	390	7	unit	unit	NN
cord-329515-ra20actc	390	8	from	from	IN
cord-329515-ra20actc	390	9	which	which	WDT
cord-329515-ra20actc	390	10	higher	high	JJR
cord-329515-ra20actc	390	11	oligomeric	oligomeric	JJ
cord-329515-ra20actc	390	12	structures	structure	NNS
cord-329515-ra20actc	390	13	are	be	VBP
cord-329515-ra20actc	390	14	built	build	VBN
cord-329515-ra20actc	390	15	.	.	.
cord-329515-ra20actc	391	1	Upon	upon	IN
cord-329515-ra20actc	391	2	reaching	reach	VBG
cord-329515-ra20actc	391	3	their	-PRON-	PRP$
cord-329515-ra20actc	391	4	final	final	JJ
cord-329515-ra20actc	391	5	destination	destination	NN
cord-329515-ra20actc	391	6	,	,	,
cord-329515-ra20actc	391	7	larger	large	JJR
cord-329515-ra20actc	391	8	complexes	complex	NNS
cord-329515-ra20actc	391	9	form	form	NN
cord-329515-ra20actc	391	10	,	,	,
cord-329515-ra20actc	391	11	requiring	require	VBG
cord-329515-ra20actc	391	12	interactions	interaction	NNS
cord-329515-ra20actc	391	13	of	of	IN
cord-329515-ra20actc	391	14	the	the	DT
cord-329515-ra20actc	391	15	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	391	16	tails	tail	NNS
cord-329515-ra20actc	391	17	as	as	RB
cord-329515-ra20actc	391	18	well	well	RB
cord-329515-ra20actc	391	19	as	as	IN
cord-329515-ra20actc	391	20	the	the	DT
cord-329515-ra20actc	391	21	lumenal	lumenal	NNP
cord-329515-ra20actc	391	22	and	and	CC
cord-329515-ra20actc	391	23	transmembrane	transmembrane	NN
cord-329515-ra20actc	391	24	domains	domain	NNS
cord-329515-ra20actc	391	25	.	.	.
cord-329515-ra20actc	392	1	The	the	DT
cord-329515-ra20actc	392	2	amino	amino	NN
cord-329515-ra20actc	392	3	-	-	HYPH
cord-329515-ra20actc	392	4	terminal	terminal	NN
cord-329515-ra20actc	392	5	23	23	CD
cord-329515-ra20actc	392	6	residues	residue	NNS
cord-329515-ra20actc	392	7	of	of	IN
cord-329515-ra20actc	392	8	the	the	DT
cord-329515-ra20actc	392	9	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	392	10	tails	tail	NNS
cord-329515-ra20actc	392	11	could	could	MD
cord-329515-ra20actc	392	12	either	either	CC
cord-329515-ra20actc	392	13	be	be	VB
cord-329515-ra20actc	392	14	directly	directly	RB
cord-329515-ra20actc	392	15	involved	involve	VBN
cord-329515-ra20actc	392	16	in	in	IN
cord-329515-ra20actc	392	17	the	the	DT
cord-329515-ra20actc	392	18	interactions	interaction	NNS
cord-329515-ra20actc	392	19	or	or	CC
cord-329515-ra20actc	392	20	,	,	,
cord-329515-ra20actc	392	21	more	more	RBR
cord-329515-ra20actc	392	22	likely	likely	JJ
cord-329515-ra20actc	392	23	,	,	,
cord-329515-ra20actc	392	24	guarantee	guarantee	VB
cord-329515-ra20actc	392	25	a	a	DT
cord-329515-ra20actc	392	26	conformation	conformation	NN
cord-329515-ra20actc	392	27	of	of	IN
cord-329515-ra20actc	392	28	the	the	DT
cord-329515-ra20actc	392	29	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	392	30	tail	tail	NN
cord-329515-ra20actc	392	31	that	that	WDT
cord-329515-ra20actc	392	32	favors	favor	VBZ
cord-329515-ra20actc	392	33	higher	high	JJR
cord-329515-ra20actc	392	34	order	order	NN
cord-329515-ra20actc	392	35	assembly	assembly	NN
cord-329515-ra20actc	392	36	.	.	.
cord-329515-ra20actc	393	1	The	the	DT
cord-329515-ra20actc	393	2	association	association	NN
cord-329515-ra20actc	393	3	of	of	IN
cord-329515-ra20actc	393	4	p63	p63	NNP
cord-329515-ra20actc	393	5	into	into	IN
cord-329515-ra20actc	393	6	large	large	JJ
cord-329515-ra20actc	393	7	complexes	complex	NNS
cord-329515-ra20actc	393	8	could	could	MD
cord-329515-ra20actc	393	9	prevent	prevent	VB
cord-329515-ra20actc	393	10	p63	p63	NN
cord-329515-ra20actc	393	11	molecules	molecule	NNS
cord-329515-ra20actc	393	12	from	from	IN
cord-329515-ra20actc	393	13	entering	enter	VBG
cord-329515-ra20actc	393	14	budding	bud	VBG
cord-329515-ra20actc	393	15	vesicles	vesicle	NNS
cord-329515-ra20actc	393	16	and	and	CC
cord-329515-ra20actc	393	17	thereby	thereby	RB
cord-329515-ra20actc	393	18	provide	provide	VB
cord-329515-ra20actc	393	19	a	a	DT
cord-329515-ra20actc	393	20	mechanism	mechanism	NN
cord-329515-ra20actc	393	21	for	for	IN
cord-329515-ra20actc	393	22	retention	retention	NN
cord-329515-ra20actc	393	23	.	.	.
cord-329515-ra20actc	394	1	Alternatively	alternatively	RB
cord-329515-ra20actc	394	2	,	,	,
cord-329515-ra20actc	394	3	failure	failure	NN
cord-329515-ra20actc	394	4	of	of	IN
cord-329515-ra20actc	394	5	the	the	DT
cord-329515-ra20actc	394	6	mutant	mutant	JJ
cord-329515-ra20actc	394	7	p63	p63	CD
cord-329515-ra20actc	394	8	molecules	molecule	NNS
cord-329515-ra20actc	394	9	to	to	TO
cord-329515-ra20actc	394	10	form	form	VB
cord-329515-ra20actc	394	11	the	the	DT
cord-329515-ra20actc	394	12	higher	high	JJR
cord-329515-ra20actc	394	13	order	order	NN
cord-329515-ra20actc	394	14	complexes	complex	NNS
cord-329515-ra20actc	394	15	would	would	MD
cord-329515-ra20actc	394	16	result	result	VB
cord-329515-ra20actc	394	17	in	in	IN
cord-329515-ra20actc	394	18	leakage	leakage	NN
cord-329515-ra20actc	394	19	of	of	IN
cord-329515-ra20actc	394	20	the	the	DT
cord-329515-ra20actc	394	21	molecules	molecule	NNS
cord-329515-ra20actc	394	22	out	out	IN
cord-329515-ra20actc	394	23	of	of	IN
cord-329515-ra20actc	394	24	the	the	DT
cord-329515-ra20actc	394	25	compartment	compartment	NN
cord-329515-ra20actc	394	26	with	with	IN
cord-329515-ra20actc	394	27	eventual	eventual	JJ
cord-329515-ra20actc	394	28	delivery	delivery	NN
cord-329515-ra20actc	394	29	to	to	IN
cord-329515-ra20actc	394	30	the	the	DT
cord-329515-ra20actc	394	31	cell	cell	NN
cord-329515-ra20actc	394	32	surface	surface	NN
cord-329515-ra20actc	394	33	.	.	.
cord-329515-ra20actc	395	1	This	this	DT
cord-329515-ra20actc	395	2	proposed	propose	VBN
cord-329515-ra20actc	395	3	model	model	NN
cord-329515-ra20actc	395	4	for	for	IN
cord-329515-ra20actc	395	5	the	the	DT
cord-329515-ra20actc	395	6	localization	localization	NN
cord-329515-ra20actc	395	7	of	of	IN
cord-329515-ra20actc	395	8	p63	p63	CD
cord-329515-ra20actc	395	9	involves	involve	VBZ
cord-329515-ra20actc	395	10	a	a	DT
cord-329515-ra20actc	395	11	retention	retention	NN
cord-329515-ra20actc	395	12	rather	rather	RB
cord-329515-ra20actc	395	13	than	than	IN
cord-329515-ra20actc	395	14	a	a	DT
cord-329515-ra20actc	395	15	retrieval	retrieval	NN
cord-329515-ra20actc	395	16	mechanism	mechanism	NN
cord-329515-ra20actc	395	17	,	,	,
cord-329515-ra20actc	395	18	which	which	WDT
cord-329515-ra20actc	395	19	is	be	VBZ
cord-329515-ra20actc	395	20	compatible	compatible	JJ
cord-329515-ra20actc	395	21	with	with	IN
cord-329515-ra20actc	395	22	previous	previous	JJ
cord-329515-ra20actc	395	23	data	datum	NNS
cord-329515-ra20actc	395	24	suggesting	suggest	VBG
cord-329515-ra20actc	395	25	that	that	IN
cord-329515-ra20actc	395	26	p63	p63	NN
cord-329515-ra20actc	395	27	is	be	VBZ
cord-329515-ra20actc	395	28	a	a	DT
cord-329515-ra20actc	395	29	stably	stably	RB
cord-329515-ra20actc	395	30	anchored	anchor	VBN
cord-329515-ra20actc	395	31	resident	resident	JJ
cord-329515-ra20actc	395	32	protein	protein	NN
cord-329515-ra20actc	395	33	.	.	.
cord-329515-ra20actc	396	1	Oligomerization	Oligomerization	NNP
cord-329515-ra20actc	396	2	has	have	VBZ
cord-329515-ra20actc	396	3	also	also	RB
cord-329515-ra20actc	396	4	been	be	VBN
cord-329515-ra20actc	396	5	suggested	suggest	VBN
cord-329515-ra20actc	396	6	as	as	IN
cord-329515-ra20actc	396	7	a	a	DT
cord-329515-ra20actc	396	8	retention	retention	NN
cord-329515-ra20actc	396	9	mechanism	mechanism	NN
cord-329515-ra20actc	396	10	for	for	IN
cord-329515-ra20actc	396	11	proteins	protein	NNS
cord-329515-ra20actc	396	12	in	in	IN
cord-329515-ra20actc	396	13	the	the	DT
cord-329515-ra20actc	396	14	Golgi	Golgi	NNP
cord-329515-ra20actc	396	15	apparatus	apparatus	NN
cord-329515-ra20actc	396	16	(	(	-LRB-
cord-329515-ra20actc	396	17	Machamer	Machamer	NNP
cord-329515-ra20actc	396	18	1991	1991	CD
cord-329515-ra20actc	396	19	;	;	:
cord-329515-ra20actc	396	20	Nilsson	Nilsson	NNP
cord-329515-ra20actc	396	21	et	et	NNP
cord-329515-ra20actc	396	22	al	al	NNP
cord-329515-ra20actc	396	23	.	.	.
cord-329515-ra20actc	397	1	,	,	,
cord-329515-ra20actc	397	2	1991	1991	CD
cord-329515-ra20actc	398	1	Nilsson	Nilsson	NNP
cord-329515-ra20actc	398	2	et	et	NNP
cord-329515-ra20actc	398	3	al	al	NNP
cord-329515-ra20actc	398	4	.	.	.
cord-329515-ra20actc	399	1	,	,	,
cord-329515-ra20actc	399	2	,	,	,
cord-329515-ra20actc	399	3	1993	1993	CD
cord-329515-ra20actc	399	4	Nilsson	Nilsson	NNP
cord-329515-ra20actc	399	5	et	et	NNP
cord-329515-ra20actc	399	6	al	al	NNP
cord-329515-ra20actc	399	7	.	.	NNP
cord-329515-ra20actc	399	8	,	,	,
cord-329515-ra20actc	400	1	,	,	,
cord-329515-ra20actc	400	2	1994	1994	CD
cord-329515-ra20actc	400	3	Swift	Swift	NNP
cord-329515-ra20actc	400	4	and	and	CC
cord-329515-ra20actc	400	5	Machamer	Machamer	NNP
cord-329515-ra20actc	400	6	,	,	,
cord-329515-ra20actc	400	7	1991	1991	CD
cord-329515-ra20actc	400	8	)	)	-RRB-
cord-329515-ra20actc	400	9	.	.	.
cord-329515-ra20actc	401	1	The	the	DT
cord-329515-ra20actc	401	2	only	only	JJ
cord-329515-ra20actc	401	3	example	example	NN
cord-329515-ra20actc	401	4	where	where	WRB
cord-329515-ra20actc	401	5	retention	retention	NN
cord-329515-ra20actc	401	6	in	in	IN
cord-329515-ra20actc	401	7	this	this	DT
cord-329515-ra20actc	401	8	organelle	organelle	NN
cord-329515-ra20actc	401	9	has	have	VBZ
cord-329515-ra20actc	401	10	actually	actually	RB
cord-329515-ra20actc	401	11	been	be	VBN
cord-329515-ra20actc	401	12	correlated	correlate	VBN
cord-329515-ra20actc	401	13	with	with	IN
cord-329515-ra20actc	401	14	oligomerization	oligomerization	NN
cord-329515-ra20actc	401	15	is	be	VBZ
cord-329515-ra20actc	401	16	a	a	DT
cord-329515-ra20actc	401	17	chimeric	chimeric	JJ
cord-329515-ra20actc	401	18	membrane	membrane	NN
cord-329515-ra20actc	401	19	protein	protein	NN
cord-329515-ra20actc	401	20	in	in	IN
cord-329515-ra20actc	401	21	which	which	WDT
cord-329515-ra20actc	401	22	the	the	DT
cord-329515-ra20actc	401	23	membrane	membrane	NN
cord-329515-ra20actc	401	24	-	-	HYPH
cord-329515-ra20actc	401	25	spanning	span	VBG
cord-329515-ra20actc	401	26	domain	domain	NN
cord-329515-ra20actc	401	27	of	of	IN
cord-329515-ra20actc	401	28	VSV	VSV	NNP
cord-329515-ra20actc	401	29	G	G	NNP
cord-329515-ra20actc	401	30	protein	protein	NN
cord-329515-ra20actc	401	31	was	be	VBD
cord-329515-ra20actc	401	32	replaced	replace	VBN
cord-329515-ra20actc	401	33	with	with	IN
cord-329515-ra20actc	401	34	the	the	DT
cord-329515-ra20actc	401	35	first	first	JJ
cord-329515-ra20actc	401	36	membrane	membrane	NN
cord-329515-ra20actc	401	37	-	-	HYPH
cord-329515-ra20actc	401	38	spanning	span	VBG
cord-329515-ra20actc	401	39	domain	domain	NN
cord-329515-ra20actc	401	40	of	of	IN
cord-329515-ra20actc	401	41	the	the	DT
cord-329515-ra20actc	401	42	M	M	NNP
cord-329515-ra20actc	401	43	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	401	44	of	of	IN
cord-329515-ra20actc	401	45	avian	avian	JJ
cord-329515-ra20actc	401	46	coronavirus	coronavirus	NN
cord-329515-ra20actc	401	47	(	(	-LRB-
cord-329515-ra20actc	401	48	Weisz	Weisz	NNP
cord-329515-ra20actc	401	49	et	et	NNP
cord-329515-ra20actc	401	50	al	al	NNP
cord-329515-ra20actc	401	51	.	.	NNP
cord-329515-ra20actc	401	52	,	,	,
cord-329515-ra20actc	401	53	1993	1993	CD
cord-329515-ra20actc	401	54	)	)	-RRB-
cord-329515-ra20actc	401	55	.	.	.
cord-329515-ra20actc	402	1	However	however	RB
cord-329515-ra20actc	402	2	,	,	,
cord-329515-ra20actc	402	3	in	in	IN
cord-329515-ra20actc	402	4	contrast	contrast	NN
cord-329515-ra20actc	402	5	to	to	IN
cord-329515-ra20actc	402	6	the	the	DT
cord-329515-ra20actc	402	7	chimera	chimera	NN
cord-329515-ra20actc	402	8	,	,	,
cord-329515-ra20actc	402	9	oligomerization	oligomerization	NN
cord-329515-ra20actc	402	10	of	of	IN
cord-329515-ra20actc	402	11	the	the	DT
cord-329515-ra20actc	402	12	intact	intact	JJ
cord-329515-ra20actc	402	13	M	m	NN
cord-329515-ra20actc	402	14	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	402	15	could	could	MD
cord-329515-ra20actc	402	16	not	not	RB
cord-329515-ra20actc	402	17	be	be	VB
cord-329515-ra20actc	402	18	demonstrated	demonstrate	VBN
cord-329515-ra20actc	402	19	.	.	.
cord-329515-ra20actc	403	1	Recently	recently	RB
cord-329515-ra20actc	403	2	,	,	,
cord-329515-ra20actc	403	3	Nilsson	Nilsson	NNP
cord-329515-ra20actc	403	4	et	et	NNP
cord-329515-ra20actc	403	5	al	al	NNP
cord-329515-ra20actc	403	6	.	.	.
cord-329515-ra20actc	404	1	(	(	-LRB-
cord-329515-ra20actc	404	2	1993	1993	CD
cord-329515-ra20actc	404	3	Nilsson	Nilsson	NNP
cord-329515-ra20actc	404	4	et	et	NNP
cord-329515-ra20actc	404	5	al	al	NNP
cord-329515-ra20actc	404	6	.	.	.
cord-329515-ra20actc	405	1	(	(	-LRB-
cord-329515-ra20actc	405	2	,	,	,
cord-329515-ra20actc	405	3	1994	1994	CD
cord-329515-ra20actc	405	4	have	have	VBP
cord-329515-ra20actc	405	5	proposed	propose	VBN
cord-329515-ra20actc	405	6	a	a	DT
cord-329515-ra20actc	405	7	model	model	NN
cord-329515-ra20actc	405	8	whereby	whereby	WRB
cord-329515-ra20actc	405	9	Golgi	Golgi	NNP
cord-329515-ra20actc	405	10	enzymes	enzyme	NNS
cord-329515-ra20actc	405	11	form	form	VBP
cord-329515-ra20actc	405	12	homo	homo	NN
cord-329515-ra20actc	405	13	-	-	HYPH
cord-329515-ra20actc	405	14	dimers	dimer	NNS
cord-329515-ra20actc	405	15	in	in	IN
cord-329515-ra20actc	405	16	which	which	WDT
cord-329515-ra20actc	405	17	the	the	DT
cord-329515-ra20actc	405	18	lumenal	lumenal	JJ
cord-329515-ra20actc	405	19	domains	domain	NNS
cord-329515-ra20actc	405	20	are	be	VBP
cord-329515-ra20actc	405	21	bound	bind	VBN
cord-329515-ra20actc	405	22	together	together	RB
cord-329515-ra20actc	405	23	while	while	IN
cord-329515-ra20actc	405	24	the	the	DT
cord-329515-ra20actc	405	25	transmembrane	transmembrane	NN
cord-329515-ra20actc	405	26	domains	domain	NNS
cord-329515-ra20actc	405	27	interact	interact	VBP
cord-329515-ra20actc	405	28	with	with	IN
cord-329515-ra20actc	405	29	those	those	DT
cord-329515-ra20actc	405	30	of	of	IN
cord-329515-ra20actc	405	31	identical	identical	JJ
cord-329515-ra20actc	405	32	or	or	CC
cord-329515-ra20actc	405	33	related	related	JJ
cord-329515-ra20actc	405	34	enzymes	enzyme	NNS
cord-329515-ra20actc	405	35	of	of	IN
cord-329515-ra20actc	405	36	the	the	DT
cord-329515-ra20actc	405	37	same	same	JJ
cord-329515-ra20actc	405	38	Golgi	Golgi	NNP
cord-329515-ra20actc	405	39	cisternae	cisternae	NNP
cord-329515-ra20actc	405	40	to	to	TO
cord-329515-ra20actc	405	41	form	form	VB
cord-329515-ra20actc	405	42	hetero	hetero	NNS
cord-329515-ra20actc	405	43	-	-	NNS
cord-329515-ra20actc	405	44	oligomers	oligomer	NNS
cord-329515-ra20actc	405	45	.	.	.
cord-329515-ra20actc	406	1	The	the	DT
cord-329515-ra20actc	406	2	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	406	3	domains	domain	NNS
cord-329515-ra20actc	406	4	would	would	MD
cord-329515-ra20actc	406	5	be	be	VB
cord-329515-ra20actc	406	6	attached	attach	VBN
cord-329515-ra20actc	406	7	to	to	IN
cord-329515-ra20actc	406	8	an	an	DT
cord-329515-ra20actc	406	9	underlying	underlying	JJ
cord-329515-ra20actc	406	10	matrix	matrix	NN
cord-329515-ra20actc	406	11	to	to	TO
cord-329515-ra20actc	406	12	stabilize	stabilize	VB
cord-329515-ra20actc	406	13	larger	large	JJR
cord-329515-ra20actc	406	14	arrays	array	NNS
cord-329515-ra20actc	406	15	.	.	.
cord-329515-ra20actc	407	1	Although	although	IN
cord-329515-ra20actc	407	2	similar	similar	JJ
cord-329515-ra20actc	407	3	in	in	IN
cord-329515-ra20actc	407	4	the	the	DT
cord-329515-ra20actc	407	5	overall	overall	JJ
cord-329515-ra20actc	407	6	architecture	architecture	NN
cord-329515-ra20actc	407	7	,	,	,
cord-329515-ra20actc	407	8	this	this	DT
cord-329515-ra20actc	407	9	Golgi	Golgi	NNP
cord-329515-ra20actc	407	10	model	model	NN
cord-329515-ra20actc	407	11	differs	differ	VBZ
cord-329515-ra20actc	407	12	from	from	IN
cord-329515-ra20actc	407	13	the	the	DT
cord-329515-ra20actc	407	14	model	model	NN
cord-329515-ra20actc	407	15	supported	support	VBN
cord-329515-ra20actc	407	16	by	by	IN
cord-329515-ra20actc	407	17	the	the	DT
cord-329515-ra20actc	407	18	p63	p63	CD
cord-329515-ra20actc	407	19	data	datum	NNS
cord-329515-ra20actc	407	20	in	in	IN
cord-329515-ra20actc	407	21	several	several	JJ
cord-329515-ra20actc	407	22	ways	way	NNS
cord-329515-ra20actc	407	23	.	.	.
cord-329515-ra20actc	408	1	In	in	IN
cord-329515-ra20actc	408	2	particular	particular	JJ
cord-329515-ra20actc	408	3	,	,	,
cord-329515-ra20actc	408	4	the	the	DT
cord-329515-ra20actc	408	5	domains	domain	NNS
cord-329515-ra20actc	408	6	responsible	responsible	JJ
cord-329515-ra20actc	408	7	for	for	IN
cord-329515-ra20actc	408	8	the	the	DT
cord-329515-ra20actc	408	9	formation	formation	NN
cord-329515-ra20actc	408	10	of	of	IN
cord-329515-ra20actc	408	11	higher	high	JJR
cord-329515-ra20actc	408	12	order	order	NN
cord-329515-ra20actc	408	13	structures	structure	NNS
cord-329515-ra20actc	408	14	(	(	-LRB-
cord-329515-ra20actc	408	15	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	408	16	tail	tail	NN
cord-329515-ra20actc	408	17	versus	versus	IN
cord-329515-ra20actc	408	18	transmembrane	transmembrane	NN
cord-329515-ra20actc	408	19	domain	domain	NN
cord-329515-ra20actc	408	20	)	)	-RRB-
cord-329515-ra20actc	408	21	and	and	CC
cord-329515-ra20actc	408	22	the	the	DT
cord-329515-ra20actc	408	23	kind	kind	NN
cord-329515-ra20actc	408	24	of	of	IN
cord-329515-ra20actc	408	25	oligomers	oligomer	NNS
cord-329515-ra20actc	408	26	formed	form	VBN
cord-329515-ra20actc	408	27	(	(	-LRB-
cord-329515-ra20actc	408	28	homo	homo	NN
cord-329515-ra20actc	408	29	-	-	HYPH
cord-329515-ra20actc	408	30	versus	versus	IN
cord-329515-ra20actc	408	31	hetero	hetero	NNS
cord-329515-ra20actc	408	32	-	-	NNS
cord-329515-ra20actc	408	33	oligomers	oligomer	NNS
cord-329515-ra20actc	408	34	)	)	-RRB-
cord-329515-ra20actc	408	35	are	be	VBP
cord-329515-ra20actc	408	36	distinct	distinct	JJ
cord-329515-ra20actc	408	37	.	.	.
cord-329515-ra20actc	409	1	Taken	take	VBN
cord-329515-ra20actc	409	2	together	together	RB
cord-329515-ra20actc	409	3	,	,	,
cord-329515-ra20actc	409	4	oligomerization	oligomerization	NN
cord-329515-ra20actc	409	5	is	be	VBZ
cord-329515-ra20actc	409	6	likely	likely	JJ
cord-329515-ra20actc	409	7	to	to	TO
cord-329515-ra20actc	409	8	be	be	VB
cord-329515-ra20actc	409	9	a	a	DT
cord-329515-ra20actc	409	10	general	general	JJ
cord-329515-ra20actc	409	11	mechanism	mechanism	NN
cord-329515-ra20actc	409	12	that	that	WDT
cord-329515-ra20actc	409	13	specifies	specify	VBZ
cord-329515-ra20actc	409	14	location	location	NN
cord-329515-ra20actc	409	15	of	of	IN
cord-329515-ra20actc	409	16	proteins	protein	NNS
cord-329515-ra20actc	409	17	in	in	IN
cord-329515-ra20actc	409	18	different	different	JJ
cord-329515-ra20actc	409	19	compartments	compartment	NNS
cord-329515-ra20actc	409	20	of	of	IN
cord-329515-ra20actc	409	21	the	the	DT
cord-329515-ra20actc	409	22	secretory	secretory	JJ
cord-329515-ra20actc	409	23	pathway	pathway	NN
cord-329515-ra20actc	409	24	.	.	.
cord-329515-ra20actc	410	1	Oligomerization	Oligomerization	NNP
cord-329515-ra20actc	410	2	per	per	IN
cord-329515-ra20actc	410	3	se	se	FW
cord-329515-ra20actc	410	4	,	,	,
cord-329515-ra20actc	410	5	however	however	RB
cord-329515-ra20actc	410	6	,	,	,
cord-329515-ra20actc	410	7	seems	seem	VBZ
cord-329515-ra20actc	410	8	to	to	TO
cord-329515-ra20actc	410	9	be	be	VB
cord-329515-ra20actc	410	10	achievable	achievable	JJ
cord-329515-ra20actc	410	11	by	by	IN
cord-329515-ra20actc	410	12	different	different	JJ
cord-329515-ra20actc	410	13	mechanisms	mechanism	NNS
cord-329515-ra20actc	410	14	and	and	CC
cord-329515-ra20actc	410	15	forms	form	NNS
cord-329515-ra20actc	410	16	of	of	IN
cord-329515-ra20actc	410	17	interactions	interaction	NNS
cord-329515-ra20actc	410	18	.	.	.
cord-329515-ra20actc	411	1	Golgi	Golgi	NNP
cord-329515-ra20actc	411	2	retention	retention	NN
cord-329515-ra20actc	411	3	of	of	IN
cord-329515-ra20actc	411	4	a	a	DT
cord-329515-ra20actc	411	5	trans	trans	JJ
cord-329515-ra20actc	411	6	-	-	JJ
cord-329515-ra20actc	411	7	Golgi	Golgi	NNP
cord-329515-ra20actc	411	8	membrane	membrane	NN
cord-329515-ra20actc	411	9	protein	protein	NN
cord-329515-ra20actc	411	10	,	,	,
cord-329515-ra20actc	411	11	galactosyltransferase	galactosyltransferase	NNP
cord-329515-ra20actc	411	12	,	,	,
cord-329515-ra20actc	411	13	requires	require	VBZ
cord-329515-ra20actc	411	14	cysteine	cysteine	NN
cord-329515-ra20actc	411	15	and	and	CC
cord-329515-ra20actc	411	16	histidine	histidine	NN
cord-329515-ra20actc	411	17	residues	residue	NNS
cord-329515-ra20actc	411	18	within	within	IN
cord-329515-ra20actc	411	19	the	the	DT
cord-329515-ra20actc	411	20	membrane	membrane	NN
cord-329515-ra20actc	411	21	-	-	HYPH
cord-329515-ra20actc	411	22	anchoring	anchor	VBG
cord-329515-ra20actc	411	23	domain	domain	NN
cord-329515-ra20actc	412	1	The	the	DT
cord-329515-ra20actc	412	2	Golgi	Golgi	NNP
cord-329515-ra20actc	412	3	sorting	sorting	NN
cord-329515-ra20actc	412	4	domain	domain	NN
cord-329515-ra20actc	412	5	of	of	IN
cord-329515-ra20actc	412	6	eoronavirus	eoronavirus	NN
cord-329515-ra20actc	412	7	E1	E1	NNP
cord-329515-ra20actc	412	8	protein	protein	NN
cord-329515-ra20actc	412	9	TGN38	TGN38	NNP
cord-329515-ra20actc	412	10	is	be	VBZ
cord-329515-ra20actc	412	11	maintained	maintain	VBN
cord-329515-ra20actc	412	12	in	in	IN
cord-329515-ra20actc	412	13	the	the	DT
cord-329515-ra20actc	412	14	trans	trans	NNP
cord-329515-ra20actc	412	15	-	-	NNP
cord-329515-ra20actc	412	16	Golgi	Golgi	NNP
cord-329515-ra20actc	412	17	network	network	NN
cord-329515-ra20actc	412	18	by	by	IN
cord-329515-ra20actc	412	19	a	a	DT
cord-329515-ra20actc	412	20	tyrosine	tyrosine	NN
cord-329515-ra20actc	412	21	-	-	HYPH
cord-329515-ra20actc	412	22	eontaining	eontaine	VBG
cord-329515-ra20actc	412	23	motif	motif	NN
cord-329515-ra20actc	412	24	in	in	IN
cord-329515-ra20actc	412	25	the	the	DT
cord-329515-ra20actc	412	26	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	412	27	domain	domain	NN
cord-329515-ra20actc	413	1	The	the	DT
cord-329515-ra20actc	413	2	transmembrane	transmembrane	NN
cord-329515-ra20actc	413	3	and	and	CC
cord-329515-ra20actc	413	4	flanking	flanking	JJ
cord-329515-ra20actc	413	5	sequences	sequence	NNS
cord-329515-ra20actc	413	6	of	of	IN
cord-329515-ra20actc	413	7	1,2N	1,2n	CD
cord-329515-ra20actc	413	8	-	-	HYPH
cord-329515-ra20actc	413	9	acetylglucosaminyltransferase	acetylglucosaminyltransferase	NN
cord-329515-ra20actc	413	10	I	-PRON-	PRP
cord-329515-ra20actc	413	11	specify	specify	VBP
cord-329515-ra20actc	413	12	medial	medial	JJ
cord-329515-ra20actc	413	13	Golgi	Golgi	NNP
cord-329515-ra20actc	413	14	localization	localization	NN
cord-329515-ra20actc	413	15	Localization	localization	NN
cord-329515-ra20actc	413	16	of	of	IN
cord-329515-ra20actc	413	17	low	low	JJ
cord-329515-ra20actc	413	18	molecular	molecular	JJ
cord-329515-ra20actc	413	19	weight	weight	NN
cord-329515-ra20actc	413	20	GTP	gtp	NN
cord-329515-ra20actc	413	21	-	-	HYPH
cord-329515-ra20actc	413	22	binding	bind	VBG
cord-329515-ra20actc	413	23	proteins	protein	NNS
cord-329515-ra20actc	413	24	to	to	IN
cord-329515-ra20actc	413	25	exocytic	exocytic	VB
cord-329515-ra20actc	413	26	and	and	CC
cord-329515-ra20actc	413	27	endocytie	endocytie	NN
cord-329515-ra20actc	413	28	compartments	compartment	NNS
cord-329515-ra20actc	414	1	Specific	specific	JJ
cord-329515-ra20actc	414	2	sequences	sequence	NNS
cord-329515-ra20actc	414	3	in	in	IN
cord-329515-ra20actc	414	4	the	the	DT
cord-329515-ra20actc	414	5	signal	signal	NN
cord-329515-ra20actc	414	6	anchor	anchor	NN
cord-329515-ra20actc	414	7	of	of	IN
cord-329515-ra20actc	414	8	the/3-galactoside-2,6	the/3-galactoside-2,6	NNP
cord-329515-ra20actc	415	1	sialyltransferase	sialyltransferase	NNP
cord-329515-ra20actc	415	2	are	be	VBP
cord-329515-ra20actc	415	3	not	not	RB
cord-329515-ra20actc	415	4	essential	essential	JJ
cord-329515-ra20actc	415	5	for	for	IN
cord-329515-ra20actc	415	6	Golgi	Golgi	NNP
cord-329515-ra20actc	415	7	localization	localization	NN
cord-329515-ra20actc	415	8	Beta	beta	NN
cord-329515-ra20actc	415	9	-	-	HYPH
cord-329515-ra20actc	415	10	COP	cop	NN
cord-329515-ra20actc	415	11	,	,	,
cord-329515-ra20actc	415	12	a	a	DT
cord-329515-ra20actc	415	13	110	110	CD
cord-329515-ra20actc	415	14	kd	kd	NNP
cord-329515-ra20actc	415	15	protein	protein	NN
cord-329515-ra20actc	415	16	associated	associate	VBN
cord-329515-ra20actc	415	17	with	with	IN
cord-329515-ra20actc	415	18	non	non	JJ
cord-329515-ra20actc	415	19	--	--	JJ
cord-329515-ra20actc	415	20	clathrin	clathrin	JJ
cord-329515-ra20actc	415	21	coated	coat	VBN
cord-329515-ra20actc	415	22	vesicles	vesicle	NNS
cord-329515-ra20actc	415	23	and	and	CC
cord-329515-ra20actc	415	24	the	the	DT
cord-329515-ra20actc	415	25	Oolgi	Oolgi	NNP
cord-329515-ra20actc	415	26	complex	complex	NN
cord-329515-ra20actc	415	27	,	,	,
cord-329515-ra20actc	415	28	shows	show	VBZ
cord-329515-ra20actc	415	29	homology	homology	NN
cord-329515-ra20actc	415	30	to	to	IN
cord-329515-ra20actc	415	31	beta	beta	NN
cord-329515-ra20actc	415	32	-	-	HYPH
cord-329515-ra20actc	415	33	adaptin	adaptin	NNS
cord-329515-ra20actc	415	34	Replacement	replacement	NN
cord-329515-ra20actc	415	35	of	of	IN
cord-329515-ra20actc	415	36	insulin	insulin	NN
cord-329515-ra20actc	415	37	receptor	receptor	NN
cord-329515-ra20actc	415	38	tyrosine	tyrosine	NN
cord-329515-ra20actc	415	39	residues	residue	NNS
cord-329515-ra20actc	415	40	1162	1162	CD
cord-329515-ra20actc	415	41	and	and	CC
cord-329515-ra20actc	415	42	1163	1163	CD
cord-329515-ra20actc	415	43	compromises	compromise	VBZ
cord-329515-ra20actc	415	44	insulin	insulin	NN
cord-329515-ra20actc	415	45	-	-	HYPH
cord-329515-ra20actc	415	46	stimulated	stimulate	VBN
cord-329515-ra20actc	415	47	kinase	kinase	NN
cord-329515-ra20actc	415	48	activities	activity	NNS
cord-329515-ra20actc	415	49	and	and	CC
cord-329515-ra20actc	415	50	uptake	uptake	NN
cord-329515-ra20actc	415	51	of	of	IN
cord-329515-ra20actc	415	52	2-deoxyglucose	2-deoxyglucose	CD
cord-329515-ra20actc	415	53	Expression	expression	NN
cord-329515-ra20actc	415	54	and	and	CC
cord-329515-ra20actc	415	55	intracellular	intracellular	JJ
cord-329515-ra20actc	415	56	transport	transport	NN
cord-329515-ra20actc	415	57	of	of	IN
cord-329515-ra20actc	415	58	mierovillus	mierovillus	NN
cord-329515-ra20actc	415	59	membrane	membrane	NN
cord-329515-ra20actc	415	60	hydrolases	hydrolase	NNS
cord-329515-ra20actc	415	61	in	in	IN
cord-329515-ra20actc	415	62	human	human	JJ
cord-329515-ra20actc	415	63	intestinal	intestinal	JJ
cord-329515-ra20actc	415	64	epithelial	epithelial	JJ
cord-329515-ra20actc	415	65	cells	cell	NNS
cord-329515-ra20actc	416	1	The	the	DT
cord-329515-ra20actc	416	2	ER	ER	NNP
cord-329515-ra20actc	416	3	-	-	HYPH
cord-329515-ra20actc	416	4	Golgi	Golgi	NNP
cord-329515-ra20actc	416	5	intermediate	intermediate	JJ
cord-329515-ra20actc	416	6	compartment	compartment	NN
cord-329515-ra20actc	416	7	Site	site	NN
cord-329515-ra20actc	416	8	-	-	HYPH
cord-329515-ra20actc	416	9	directed	direct	VBN
cord-329515-ra20actc	416	10	mutagenesis	mutagenesis	NN
cord-329515-ra20actc	416	11	by	by	IN
cord-329515-ra20actc	416	12	overlap	overlap	NN
cord-329515-ra20actc	416	13	extension	extension	NN
cord-329515-ra20actc	416	14	using	use	VBG
cord-329515-ra20actc	416	15	the	the	DT
cord-329515-ra20actc	416	16	polymerase	polymerase	NN
cord-329515-ra20actc	416	17	chain	chain	NN
cord-329515-ra20actc	416	18	reaction	reaction	NN
cord-329515-ra20actc	416	19	eDNA	edna	RB
cord-329515-ra20actc	417	1	cloning	clone	VBG
cord-329515-ra20actc	417	2	for	for	IN
cord-329515-ra20actc	417	3	a	a	DT
cord-329515-ra20actc	417	4	bile	bile	NN
cord-329515-ra20actc	417	5	canaliculus	canaliculus	NN
cord-329515-ra20actc	417	6	domainspecific	domainspecific	JJ
cord-329515-ra20actc	417	7	membrane	membrane	NNP
cord-329515-ra20actc	417	8	glyeoprotein	glyeoprotein	NNP
cord-329515-ra20actc	417	9	of	of	IN
cord-329515-ra20actc	417	10	rat	rat	NN
cord-329515-ra20actc	417	11	hepatocytes	hepatocyte	VBZ
cord-329515-ra20actc	417	12	Molecular	molecular	JJ
cord-329515-ra20actc	417	13	dissection	dissection	NN
cord-329515-ra20actc	417	14	of	of	IN
cord-329515-ra20actc	417	15	the	the	DT
cord-329515-ra20actc	417	16	NH2-terminal	NH2-terminal	NNP
cord-329515-ra20actc	417	17	signal	signal	NN
cord-329515-ra20actc	417	18	anchor	anchor	NN
cord-329515-ra20actc	417	19	sequence	sequence	NN
cord-329515-ra20actc	417	20	of	of	IN
cord-329515-ra20actc	417	21	rat	rat	NN
cord-329515-ra20actc	417	22	dipeptidylpeptidease	dipeptidylpeptidease	NN
cord-329515-ra20actc	417	23	IV	IV	NNP
cord-329515-ra20actc	417	24	Engineering	Engineering	NNP
cord-329515-ra20actc	417	25	genes	gene	NNS
cord-329515-ra20actc	417	26	without	without	IN
cord-329515-ra20actc	417	27	the	the	DT
cord-329515-ra20actc	417	28	use	use	NN
cord-329515-ra20actc	417	29	of	of	IN
cord-329515-ra20actc	417	30	restriction	restriction	NN
cord-329515-ra20actc	417	31	enz~'mes	enz~'me	NNS
cord-329515-ra20actc	417	32	:	:	:
cord-329515-ra20actc	417	33	gene	gene	NN
cord-329515-ra20actc	417	34	splicing	splicing	NN
cord-329515-ra20actc	417	35	by	by	IN
cord-329515-ra20actc	417	36	overlap	overlap	NN
cord-329515-ra20actc	417	37	extension	extension	NN
cord-329515-ra20actc	417	38	Localization	localization	NN
cord-329515-ra20actc	417	39	of	of	IN
cord-329515-ra20actc	417	40	TGN38	TGN38	NNS
cord-329515-ra20actc	417	41	to	to	IN
cord-329515-ra20actc	417	42	the	the	DT
cord-329515-ra20actc	417	43	trans	trans	NNP
cord-329515-ra20actc	417	44	-	-	NNP
cord-329515-ra20actc	417	45	Golgi	Golgi	NNP
cord-329515-ra20actc	417	46	network	network	NN
cord-329515-ra20actc	417	47	:	:	:
cord-329515-ra20actc	417	48	involvement	involvement	NN
cord-329515-ra20actc	417	49	of	of	IN
cord-329515-ra20actc	417	50	a	a	DT
cord-329515-ra20actc	417	51	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	417	52	tyrosine	tyrosine	NN
cord-329515-ra20actc	417	53	-	-	HYPH
cord-329515-ra20actc	417	54	eontaining	eontaine	VBG
cord-329515-ra20actc	417	55	sequence	sequence	NN
cord-329515-ra20actc	417	56	Identification	identification	NN
cord-329515-ra20actc	417	57	of	of	IN
cord-329515-ra20actc	417	58	a	a	DT
cord-329515-ra20actc	417	59	consensus	consensus	NN
cord-329515-ra20actc	417	60	motif	motif	NN
cord-329515-ra20actc	417	61	of	of	IN
cord-329515-ra20actc	417	62	transmembrane	transmembrane	JJ
cord-329515-ra20actc	417	63	proteins	protein	NNS
cord-329515-ra20actc	417	64	in	in	IN
cord-329515-ra20actc	417	65	the	the	DT
cord-329515-ra20actc	417	66	endoplasmic	endoplasmic	NN
cord-329515-ra20actc	417	67	reticulum	reticulum	NN
cord-329515-ra20actc	417	68	Retrieval	Retrieval	NNP
cord-329515-ra20actc	417	69	of	of	IN
cord-329515-ra20actc	417	70	transmembrane	transmembrane	NN
cord-329515-ra20actc	417	71	proteins	protein	NNS
cord-329515-ra20actc	417	72	to	to	IN
cord-329515-ra20actc	417	73	the	the	DT
cord-329515-ra20actc	417	74	ER	er	NN
cord-329515-ra20actc	418	1	The	the	DT
cord-329515-ra20actc	418	2	rate	rate	NN
cord-329515-ra20actc	418	3	of	of	IN
cord-329515-ra20actc	418	4	bulk	bulk	JJ
cord-329515-ra20actc	418	5	flow	flow	NN
cord-329515-ra20actc	418	6	from	from	IN
cord-329515-ra20actc	418	7	the	the	DT
cord-329515-ra20actc	418	8	Golgi	Golgi	NNP
cord-329515-ra20actc	418	9	to	to	IN
cord-329515-ra20actc	418	10	the	the	DT
cord-329515-ra20actc	418	11	plasma	plasma	NN
cord-329515-ra20actc	418	12	membrane	membrane	NN
cord-329515-ra20actc	418	13	Characterization	characterization	NN
cord-329515-ra20actc	418	14	of	of	IN
cord-329515-ra20actc	418	15	the	the	DT
cord-329515-ra20actc	418	16	budding	bud	VBG
cord-329515-ra20actc	418	17	compartment	compartment	NN
cord-329515-ra20actc	418	18	of	of	IN
cord-329515-ra20actc	418	19	mouse	mouse	NNP
cord-329515-ra20actc	418	20	hepatitis	hepatitis	NNP
cord-329515-ra20actc	418	21	virus	virus	NN
cord-329515-ra20actc	418	22	:	:	:
cord-329515-ra20actc	418	23	evidence	evidence	NN
cord-329515-ra20actc	418	24	that	that	DT
cord-329515-ra20actc	418	25	transport	transport	NN
cord-329515-ra20actc	418	26	from	from	IN
cord-329515-ra20actc	418	27	the	the	DT
cord-329515-ra20actc	418	28	RER	RER	NNP
cord-329515-ra20actc	418	29	to	to	IN
cord-329515-ra20actc	418	30	the	the	DT
cord-329515-ra20actc	418	31	Golgi	Golgi	NNP
cord-329515-ra20actc	418	32	complex	complex	NN
cord-329515-ra20actc	418	33	requires	require	VBZ
cord-329515-ra20actc	418	34	only	only	RB
cord-329515-ra20actc	418	35	one	one	CD
cord-329515-ra20actc	418	36	vesicular	vesicular	JJ
cord-329515-ra20actc	418	37	transport	transport	NN
cord-329515-ra20actc	418	38	step	step	NN
cord-329515-ra20actc	418	39	Cleavage	cleavage	NN
cord-329515-ra20actc	418	40	of	of	IN
cord-329515-ra20actc	418	41	structural	structural	JJ
cord-329515-ra20actc	418	42	proteins	protein	NNS
cord-329515-ra20actc	418	43	during	during	IN
cord-329515-ra20actc	418	44	the	the	DT
cord-329515-ra20actc	418	45	assembly	assembly	NN
cord-329515-ra20actc	418	46	of	of	IN
cord-329515-ra20actc	418	47	the	the	DT
cord-329515-ra20actc	418	48	head	head	NN
cord-329515-ra20actc	418	49	of	of	IN
cord-329515-ra20actc	418	50	bacteriophage	bacteriophage	NN
cord-329515-ra20actc	418	51	T4	T4	NNP
cord-329515-ra20actc	418	52	A	A	NNP
cord-329515-ra20actc	418	53	human	human	JJ
cord-329515-ra20actc	418	54	homologue	homologue	NN
cord-329515-ra20actc	418	55	of	of	IN
cord-329515-ra20actc	418	56	the	the	DT
cord-329515-ra20actc	418	57	yeast	yeast	NN
cord-329515-ra20actc	418	58	HDEL	HDEL	NNP
cord-329515-ra20actc	418	59	receptor	receptor	NN
cord-329515-ra20actc	418	60	Ligand	Ligand	NNP
cord-329515-ra20actc	418	61	-	-	HYPH
cord-329515-ra20actc	418	62	induced	induce	VBN
cord-329515-ra20actc	418	63	redistribution	redistribution	NN
cord-329515-ra20actc	418	64	of	of	IN
cord-329515-ra20actc	418	65	a	a	DT
cord-329515-ra20actc	418	66	human	human	JJ
cord-329515-ra20actc	418	67	KDEL	KDEL	NNP
cord-329515-ra20actc	418	68	receptor	receptor	NN
cord-329515-ra20actc	418	69	from	from	IN
cord-329515-ra20actc	418	70	the	the	DT
cord-329515-ra20actc	418	71	Golgi	Golgi	NNP
cord-329515-ra20actc	418	72	complex	complex	NN
cord-329515-ra20actc	418	73	to	to	IN
cord-329515-ra20actc	418	74	the	the	DT
cord-329515-ra20actc	418	75	endoplasmic	endoplasmic	NN
cord-329515-ra20actc	418	76	reticalure	reticalure	NN
cord-329515-ra20actc	418	77	Microtubule	Microtubule	NNP
cord-329515-ra20actc	418	78	-	-	HYPH
cord-329515-ra20actc	418	79	dependent	dependent	JJ
cord-329515-ra20actc	418	80	retrograde	retrograde	JJ
cord-329515-ra20actc	418	81	transport	transport	NN
cord-329515-ra20actc	418	82	of	of	IN
cord-329515-ra20actc	418	83	proteins	protein	NNS
cord-329515-ra20actc	418	84	into	into	IN
cord-329515-ra20actc	418	85	the	the	DT
cord-329515-ra20actc	418	86	ER	ER	NNP
cord-329515-ra20actc	418	87	in	in	IN
cord-329515-ra20actc	418	88	the	the	DT
cord-329515-ra20actc	418	89	presence	presence	NN
cord-329515-ra20actc	418	90	of	of	IN
cord-329515-ra20actc	418	91	brefeldin	brefeldin	NNP
cord-329515-ra20actc	419	1	A	a	DT
cord-329515-ra20actc	419	2	reveals	reveal	VBZ
cord-329515-ra20actc	419	3	an	an	DT
cord-329515-ra20actc	419	4	ER	ER	NNP
cord-329515-ra20actc	419	5	cycling	cycling	NN
cord-329515-ra20actc	419	6	pathway	pathway	NN
cord-329515-ra20actc	419	7	Immunocytochemical	Immunocytochemical	NNP
cord-329515-ra20actc	419	8	analysis	analysis	NN
cord-329515-ra20actc	419	9	of	of	IN
cord-329515-ra20actc	419	10	the	the	DT
cord-329515-ra20actc	419	11	transfer	transfer	NN
cord-329515-ra20actc	419	12	of	of	IN
cord-329515-ra20actc	419	13	vesicular	vesicular	JJ
cord-329515-ra20actc	419	14	stomatitis	stomatitis	NN
cord-329515-ra20actc	419	15	virus	virus	NN
cord-329515-ra20actc	419	16	G	g	NN
cord-329515-ra20actc	419	17	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	419	18	from	from	IN
cord-329515-ra20actc	419	19	the	the	DT
cord-329515-ra20actc	419	20	intermediate	intermediate	JJ
cord-329515-ra20actc	419	21	compartment	compartment	NN
cord-329515-ra20actc	419	22	to	to	IN
cord-329515-ra20actc	419	23	the	the	DT
cord-329515-ra20actc	419	24	Golgi	Golgi	NNP
cord-329515-ra20actc	419	25	complex	complex	JJ
cord-329515-ra20actc	419	26	Golgi	Golgi	NNP
cord-329515-ra20actc	419	27	retention	retention	NN
cord-329515-ra20actc	419	28	signals	signal	NNS
cord-329515-ra20actc	419	29	:	:	:
cord-329515-ra20actc	419	30	do	do	VBP
cord-329515-ra20actc	419	31	membranes	membrane	NNS
cord-329515-ra20actc	419	32	hold	hold	VB
cord-329515-ra20actc	419	33	the	the	DT
cord-329515-ra20actc	419	34	key	key	NN
cord-329515-ra20actc	419	35	?	?	.
cord-329515-ra20actc	420	1	Retention	Retention	NNP
cord-329515-ra20actc	420	2	of	of	IN
cord-329515-ra20actc	420	3	a	a	DT
cord-329515-ra20actc	420	4	cis	cis	NNP
cord-329515-ra20actc	420	5	-	-	HYPH
cord-329515-ra20actc	420	6	Golgi	Golgi	NNP
cord-329515-ra20actc	420	7	protein	protein	NN
cord-329515-ra20actc	420	8	requires	require	VBZ
cord-329515-ra20actc	420	9	polar	polar	JJ
cord-329515-ra20actc	420	10	residues	residue	NNS
cord-329515-ra20actc	420	11	on	on	IN
cord-329515-ra20actc	420	12	one	one	CD
cord-329515-ra20actc	420	13	face	face	NN
cord-329515-ra20actc	420	14	of	of	IN
cord-329515-ra20actc	420	15	a	a	DT
cord-329515-ra20actc	420	16	predicted	predict	VBN
cord-329515-ra20actc	420	17	a	a	DT
cord-329515-ra20actc	420	18	-	-	HYPH
cord-329515-ra20actc	420	19	helix	helix	NN
cord-329515-ra20actc	420	20	in	in	IN
cord-329515-ra20actc	420	21	the	the	DT
cord-329515-ra20actc	420	22	transmembrane	transmembrane	NN
cord-329515-ra20actc	420	23	domain	domain	NN
cord-329515-ra20actc	420	24	Molecular	molecular	JJ
cord-329515-ra20actc	420	25	cloning	cloning	NN
cord-329515-ra20actc	420	26	and	and	CC
cord-329515-ra20actc	420	27	sequence	sequence	NN
cord-329515-ra20actc	420	28	analysis	analysis	NN
cord-329515-ra20actc	420	29	of	of	IN
cord-329515-ra20actc	420	30	human	human	JJ
cord-329515-ra20actc	420	31	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	420	32	IV	IV	NNP
cord-329515-ra20actc	420	33	,	,	,
cord-329515-ra20actc	420	34	a	a	DT
cord-329515-ra20actc	420	35	serine	serine	NN
cord-329515-ra20actc	420	36	proteinase	proteinase	NN
cord-329515-ra20actc	420	37	on	on	IN
cord-329515-ra20actc	420	38	the	the	DT
cord-329515-ra20actc	420	39	cell	cell	NN
cord-329515-ra20actc	420	40	surface	surface	NN
cord-329515-ra20actc	420	41	A	a	DT
cord-329515-ra20actc	420	42	C	c	NN
cord-329515-ra20actc	420	43	-	-	HYPH
cord-329515-ra20actc	420	44	terminal	terminal	NN
cord-329515-ra20actc	420	45	signal	signal	NN
cord-329515-ra20actc	420	46	prevents	prevent	VBZ
cord-329515-ra20actc	420	47	secretion	secretion	NN
cord-329515-ra20actc	420	48	of	of	IN
cord-329515-ra20actc	420	49	lumenal	lumenal	JJ
cord-329515-ra20actc	420	50	ER	ER	NNP
cord-329515-ra20actc	420	51	proteins	protein	NNS
cord-329515-ra20actc	420	52	Sequence	sequence	NN
cord-329515-ra20actc	420	53	within	within	IN
cord-329515-ra20actc	420	54	and	and	CC
cord-329515-ra20actc	420	55	adjacent	adjacent	JJ
cord-329515-ra20actc	420	56	to	to	IN
cord-329515-ra20actc	420	57	the	the	DT
cord-329515-ra20actc	420	58	transmembrane	transmembrane	NN
cord-329515-ra20actc	420	59	segment	segment	NN
cord-329515-ra20actc	420	60	of	of	IN
cord-329515-ra20actc	420	61	alpha-2,6-sialyltransferase	alpha-2,6-sialyltransferase	NNP
cord-329515-ra20actc	420	62	specify	specify	VB
cord-329515-ra20actc	420	63	Golgi	Golgi	NNP
cord-329515-ra20actc	420	64	retention	retention	NN
cord-329515-ra20actc	420	65	Short	short	JJ
cord-329515-ra20actc	420	66	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	420	67	sequences	sequence	NNS
cord-329515-ra20actc	420	68	serve	serve	VBP
cord-329515-ra20actc	420	69	as	as	IN
cord-329515-ra20actc	420	70	retention	retention	NN
cord-329515-ra20actc	420	71	signals	signal	NNS
cord-329515-ra20actc	420	72	for	for	IN
cord-329515-ra20actc	420	73	transmembrane	transmembrane	NN
cord-329515-ra20actc	420	74	proteins	protein	NNS
cord-329515-ra20actc	420	75	in	in	IN
cord-329515-ra20actc	420	76	the	the	DT
cord-329515-ra20actc	420	77	ER	er	NN
cord-329515-ra20actc	421	1	The	the	DT
cord-329515-ra20actc	421	2	membranespanning	membranespanne	VBG
cord-329515-ra20actc	421	3	domain	domain	NN
cord-329515-ra20actc	421	4	of	of	IN
cord-329515-ra20actc	421	5	beta	beta	NN
cord-329515-ra20actc	421	6	-	-	HYPH
cord-329515-ra20actc	421	7	l,4-galactosyltransferase	l,4-galactosyltransferase	NN
cord-329515-ra20actc	421	8	specifies	specify	VBZ
cord-329515-ra20actc	421	9	trans	trans	NNP
cord-329515-ra20actc	421	10	-	-	JJ
cord-329515-ra20actc	421	11	Golgi	Golgi	NNP
cord-329515-ra20actc	421	12	localization	localization	NN
cord-329515-ra20actc	421	13	Kin	Kin	NNP
cord-329515-ra20actc	421	14	recognition	recognition	NN
cord-329515-ra20actc	421	15	.	.	.
cord-329515-ra20actc	422	1	A	a	DT
cord-329515-ra20actc	422	2	model	model	NN
cord-329515-ra20actc	422	3	for	for	IN
cord-329515-ra20actc	422	4	the	the	DT
cord-329515-ra20actc	422	5	retention	retention	NN
cord-329515-ra20actc	422	6	of	of	IN
cord-329515-ra20actc	422	7	Golgi	Golgi	NNP
cord-329515-ra20actc	422	8	enzymes	enzyme	NNS
cord-329515-ra20actc	422	9	.	.	.
cord-329515-ra20actc	423	1	FEBS	FEBS	NNP
cord-329515-ra20actc	423	2	(	(	-LRB-
cord-329515-ra20actc	423	3	Fed	Fed	NNP
cord-329515-ra20actc	423	4	.	.	.
cord-329515-ra20actc	424	1	Eur	Eur	NNP
cord-329515-ra20actc	424	2	Kin	Kin	NNP
cord-329515-ra20actc	424	3	recognition	recognition	NN
cord-329515-ra20actc	424	4	between	between	IN
cord-329515-ra20actc	424	5	medial	medial	JJ
cord-329515-ra20actc	424	6	Golgi	Golgi	NNP
cord-329515-ra20actc	424	7	enzymes	enzyme	NNS
cord-329515-ra20actc	424	8	in	in	IN
cord-329515-ra20actc	424	9	HeLa	HeLa	NNP
cord-329515-ra20actc	424	10	cells	cell	NNS
cord-329515-ra20actc	424	11	Primary	primary	JJ
cord-329515-ra20actc	424	12	structure	structure	NN
cord-329515-ra20actc	424	13	of	of	IN
cord-329515-ra20actc	424	14	rat	rat	NN
cord-329515-ra20actc	424	15	liver	liver	NN
cord-329515-ra20actc	424	16	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	424	17	IV	IV	NNP
cord-329515-ra20actc	424	18	deduced	deduce	VBD
cord-329515-ra20actc	424	19	from	from	IN
cord-329515-ra20actc	424	20	its	-PRON-	PRP$
cord-329515-ra20actc	424	21	eDNA	edna	NN
cord-329515-ra20actc	424	22	and	and	CC
cord-329515-ra20actc	424	23	identification	identification	NN
cord-329515-ra20actc	424	24	of	of	IN
cord-329515-ra20actc	424	25	the	the	DT
cord-329515-ra20actc	424	26	NH2-terminal	nh2-terminal	JJ
cord-329515-ra20actc	424	27	signal	signal	NN
cord-329515-ra20actc	424	28	sequence	sequence	NN
cord-329515-ra20actc	424	29	as	as	IN
cord-329515-ra20actc	424	30	membrane	membrane	NN
cord-329515-ra20actc	424	31	-	-	HYPH
cord-329515-ra20actc	424	32	anchoring	anchor	VBG
cord-329515-ra20actc	424	33	domain	domain	NN
cord-329515-ra20actc	424	34	Identification	identification	NN
cord-329515-ra20actc	424	35	of	of	IN
cord-329515-ra20actc	424	36	the	the	DT
cord-329515-ra20actc	424	37	active	active	JJ
cord-329515-ra20actc	424	38	site	site	NN
cord-329515-ra20actc	424	39	residues	residue	NNS
cord-329515-ra20actc	424	40	in	in	IN
cord-329515-ra20actc	424	41	dipeptidylpeptidase	dipeptidylpeptidase	NNP
cord-329515-ra20actc	424	42	IV	IV	NNP
cord-329515-ra20actc	424	43	by	by	IN
cord-329515-ra20actc	424	44	affinity	affinity	NN
cord-329515-ra20actc	424	45	labeling	labeling	NN
cord-329515-ra20actc	424	46	and	and	CC
cord-329515-ra20actc	424	47	site	site	NN
cord-329515-ra20actc	424	48	-	-	HYPH
cord-329515-ra20actc	424	49	directed	direct	VBN
cord-329515-ra20actc	424	50	mutagenesis	mutagenesis	NN
cord-329515-ra20actc	425	1	Intracellular	Intracellular	NNP
cord-329515-ra20actc	425	2	aspects	aspect	NNS
cord-329515-ra20actc	425	3	of	of	IN
cord-329515-ra20actc	425	4	the	the	DT
cord-329515-ra20actc	425	5	process	process	NN
cord-329515-ra20actc	425	6	of	of	IN
cord-329515-ra20actc	425	7	protein	protein	NN
cord-329515-ra20actc	425	8	transport	transport	NN
cord-329515-ra20actc	425	9	Control	Control	NNP
cord-329515-ra20actc	425	10	of	of	IN
cord-329515-ra20actc	425	11	protein	protein	NN
cord-329515-ra20actc	425	12	exit	exit	NN
cord-329515-ra20actc	425	13	from	from	IN
cord-329515-ra20actc	425	14	the	the	DT
cord-329515-ra20actc	425	15	ER	ER	NNP
cord-329515-ra20actc	426	1	The	the	DT
cord-329515-ra20actc	426	2	retention	retention	NN
cord-329515-ra20actc	426	3	signal	signal	NN
cord-329515-ra20actc	426	4	for	for	IN
cord-329515-ra20actc	426	5	soluble	soluble	JJ
cord-329515-ra20actc	426	6	proteins	protein	NNS
cord-329515-ra20actc	426	7	of	of	IN
cord-329515-ra20actc	426	8	the	the	DT
cord-329515-ra20actc	426	9	endoplasmic	endoplasmic	NN
cord-329515-ra20actc	426	10	reticulum	reticulum	NN
cord-329515-ra20actc	426	11	Biosynthetic	biosynthetic	JJ
cord-329515-ra20actc	426	12	protein	protein	NN
cord-329515-ra20actc	426	13	transport	transport	NN
cord-329515-ra20actc	426	14	and	and	CC
cord-329515-ra20actc	426	15	sorting	sorting	NN
cord-329515-ra20actc	426	16	by	by	IN
cord-329515-ra20actc	426	17	the	the	DT
cord-329515-ra20actc	426	18	ER	ER	NNP
cord-329515-ra20actc	426	19	and	and	CC
cord-329515-ra20actc	426	20	Golgi	Golgi	NNP
cord-329515-ra20actc	426	21	1992	1992	CD
cord-329515-ra20actc	426	22	.	.	.
cord-329515-ra20actc	427	1	1,4-galactosyltransferase	1,4-galactosyltransferase	CD
cord-329515-ra20actc	427	2	:	:	:
cord-329515-ra20actc	427	3	a	a	DT
cord-329515-ra20actc	427	4	short	short	JJ
cord-329515-ra20actc	427	5	NH2-terminal	nh2-terminal	NN
cord-329515-ra20actc	427	6	fragment	fragment	NN
cord-329515-ra20actc	427	7	that	that	WDT
cord-329515-ra20actc	427	8	includes	include	VBZ
cord-329515-ra20actc	427	9	the	the	DT
cord-329515-ra20actc	427	10	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	427	11	and	and	CC
cord-329515-ra20actc	427	12	transmembrane	transmembrane	NN
cord-329515-ra20actc	427	13	domain	domain	NN
cord-329515-ra20actc	427	14	is	be	VBZ
cord-329515-ra20actc	427	15	sufficient	sufficient	JJ
cord-329515-ra20actc	427	16	for	for	IN
cord-329515-ra20actc	427	17	retention	retention	NN
cord-329515-ra20actc	427	18	Molecular	Molecular	NNP
cord-329515-ra20actc	427	19	Cloning	Cloning	NNP
cord-329515-ra20actc	427	20	:	:	:
cord-329515-ra20actc	427	21	A	a	DT
cord-329515-ra20actc	427	22	Laboratory	Laboratory	NNP
cord-329515-ra20actc	427	23	Manual	Manual	NNP
cord-329515-ra20actc	427	24	DNA	dna	NN
cord-329515-ra20actc	427	25	sequencing	sequencing	NN
cord-329515-ra20actc	427	26	with	with	IN
cord-329515-ra20actc	427	27	chain	chain	NN
cord-329515-ra20actc	427	28	terminating	terminate	VBG
cord-329515-ra20actc	427	29	inhibitors	inhibitor	NNS
cord-329515-ra20actc	427	30	Ire	Ire	NNP
cord-329515-ra20actc	427	31	-	-	,
cord-329515-ra20actc	427	32	and	and	CC
cord-329515-ra20actc	427	33	post	post	JJ
cord-329515-ra20actc	427	34	-	-	JJ
cord-329515-ra20actc	427	35	Golgi	golgi	JJ
cord-329515-ra20actc	427	36	vacuoles	vacuole	NNS
cord-329515-ra20actc	427	37	operate	operate	VBP
cord-329515-ra20actc	427	38	in	in	IN
cord-329515-ra20actc	427	39	the	the	DT
cord-329515-ra20actc	427	40	transport	transport	NN
cord-329515-ra20actc	427	41	of	of	IN
cord-329515-ra20actc	427	42	Semliki	Semliki	NNP
cord-329515-ra20actc	427	43	Forest	Forest	NNP
cord-329515-ra20actc	427	44	virus	virus	NN
cord-329515-ra20actc	427	45	membrane	membrane	NN
cord-329515-ra20actc	427	46	glycoproteins	glycoprotein	NNS
cord-329515-ra20actc	427	47	to	to	IN
cord-329515-ra20actc	427	48	the	the	DT
cord-329515-ra20actc	427	49	cell	cell	NN
cord-329515-ra20actc	427	50	surface	surface	NN
cord-329515-ra20actc	427	51	Distribution	distribution	NN
cord-329515-ra20actc	427	52	of	of	IN
cord-329515-ra20actc	427	53	the	the	DT
cord-329515-ra20actc	427	54	intermediate	intermediate	JJ
cord-329515-ra20actc	427	55	elements	element	NNS
cord-329515-ra20actc	427	56	operating	operate	VBG
cord-329515-ra20actc	427	57	in	in	IN
cord-329515-ra20actc	427	58	ER	ER	NNP
cord-329515-ra20actc	427	59	to	to	IN
cord-329515-ra20actc	427	60	Golgi	Golgi	NNP
cord-329515-ra20actc	427	61	transport	transport	NN
cord-329515-ra20actc	427	62	Identification	identification	NN
cord-329515-ra20actc	427	63	,	,	,
cord-329515-ra20actc	427	64	by	by	IN
cord-329515-ra20actc	427	65	a	a	DT
cord-329515-ra20actc	427	66	monoclonal	monoclonal	JJ
cord-329515-ra20actc	427	67	antibody	antibody	NN
cord-329515-ra20actc	427	68	,	,	,
cord-329515-ra20actc	427	69	of	of	IN
cord-329515-ra20actc	427	70	a	a	DT
cord-329515-ra20actc	427	71	53	53	CD
cord-329515-ra20actc	427	72	kDa	kDa	NNP
cord-329515-ra20actc	427	73	protein	protein	NN
cord-329515-ra20actc	427	74	associated	associate	VBN
cord-329515-ra20actc	427	75	with	with	IN
cord-329515-ra20actc	427	76	a	a	DT
cord-329515-ra20actc	427	77	tubular	tubular	JJ
cord-329515-ra20actc	427	78	-	-	HYPH
cord-329515-ra20actc	427	79	vesicular	vesicular	JJ
cord-329515-ra20actc	427	80	compartment	compartment	NN
cord-329515-ra20actc	427	81	at	at	IN
cord-329515-ra20actc	427	82	the	the	DT
cord-329515-ra20actc	427	83	cis	cis	NNP
cord-329515-ra20actc	427	84	-	-	HYPH
cord-329515-ra20actc	427	85	side	side	NN
cord-329515-ra20actc	427	86	of	of	IN
cord-329515-ra20actc	427	87	the	the	DT
cord-329515-ra20actc	427	88	Golgi	Golgi	NNP
cord-329515-ra20actc	427	89	apparatus	apparatus	NN
cord-329515-ra20actc	427	90	Identification	identification	NN
cord-329515-ra20actc	427	91	of	of	IN
cord-329515-ra20actc	427	92	an	an	DT
cord-329515-ra20actc	427	93	intermediate	intermediate	JJ
cord-329515-ra20actc	427	94	compartment	compartment	NN
cord-329515-ra20actc	427	95	involved	involve	VBN
cord-329515-ra20actc	427	96	in	in	IN
cord-329515-ra20actc	427	97	protein	protein	NN
cord-329515-ra20actc	427	98	transport	transport	NN
cord-329515-ra20actc	427	99	from	from	IN
cord-329515-ra20actc	427	100	the	the	DT
cord-329515-ra20actc	427	101	ER	ER	NNP
cord-329515-ra20actc	427	102	to	to	IN
cord-329515-ra20actc	427	103	the	the	DT
cord-329515-ra20actc	427	104	Golgi	Golgi	NNP
cord-329515-ra20actc	427	105	apparatus	apparatus	NN
cord-329515-ra20actc	428	1	The	the	DT
cord-329515-ra20actc	428	2	isolated	isolated	JJ
cord-329515-ra20actc	428	3	ER	ER	NNP
cord-329515-ra20actc	428	4	-	-	HYPH
cord-329515-ra20actc	428	5	Golgi	Golgi	NNP
cord-329515-ra20actc	428	6	intermediate	intermediate	JJ
cord-329515-ra20actc	428	7	compartment	compartment	NN
cord-329515-ra20actc	428	8	exhibits	exhibit	VBZ
cord-329515-ra20actc	428	9	properties	property	NNS
cord-329515-ra20actc	428	10	that	that	WDT
cord-329515-ra20actc	428	11	are	be	VBP
cord-329515-ra20actc	428	12	different	different	JJ
cord-329515-ra20actc	428	13	from	from	IN
cord-329515-ra20actc	428	14	ER	ER	NNP
cord-329515-ra20actc	428	15	and	and	CC
cord-329515-ra20actc	428	16	cis	cis	NNP
cord-329515-ra20actc	428	17	-	-	HYPH
cord-329515-ra20actc	428	18	Golgi	Golgi	NNP
cord-329515-ra20actc	428	19	Characterization	Characterization	NNP
cord-329515-ra20actc	428	20	of	of	IN
cord-329515-ra20actc	428	21	a	a	DT
cord-329515-ra20actc	428	22	novel	novel	JJ
cord-329515-ra20actc	428	23	63	63	CD
cord-329515-ra20actc	428	24	kDa	kDa	NNS
cord-329515-ra20actc	428	25	membrane	membrane	NN
cord-329515-ra20actc	428	26	protein	protein	NN
cord-329515-ra20actc	428	27	:	:	:
cord-329515-ra20actc	428	28	implications	implication	NNS
cord-329515-ra20actc	428	29	for	for	IN
cord-329515-ra20actc	428	30	the	the	DT
cord-329515-ra20actc	428	31	organization	organization	NN
cord-329515-ra20actc	428	32	of	of	IN
cord-329515-ra20actc	429	1	the	the	DT
cord-329515-ra20actc	429	2	ER	ER	NNP
cord-329515-ra20actc	429	3	-	-	HYPH
cord-329515-ra20actc	429	4	to	to	IN
cord-329515-ra20actc	429	5	-	-	HYPH
cord-329515-ra20actc	429	6	Golgi	Golgi	NNP
cord-329515-ra20actc	429	7	pathway	pathway	NN
cord-329515-ra20actc	429	8	A	a	DT
cord-329515-ra20actc	429	9	reversibly	reversibly	RB
cord-329515-ra20actc	429	10	palmitoylated	palmitoylate	VBN
cord-329515-ra20actc	429	11	resident	resident	JJ
cord-329515-ra20actc	429	12	protein	protein	NN
cord-329515-ra20actc	429	13	(	(	-LRB-
cord-329515-ra20actc	429	14	p63	p63	CD
cord-329515-ra20actc	429	15	)	)	-RRB-
cord-329515-ra20actc	429	16	of	of	IN
cord-329515-ra20actc	429	17	an	an	DT
cord-329515-ra20actc	429	18	ER	ER	NNP
cord-329515-ra20actc	429	19	-	-	HYPH
cord-329515-ra20actc	429	20	Golgi	Golgi	NNP
cord-329515-ra20actc	429	21	intermediate	intermediate	JJ
cord-329515-ra20actc	429	22	compartment	compartment	NN
cord-329515-ra20actc	429	23	is	be	VBZ
cord-329515-ra20actc	429	24	related	relate	VBN
cord-329515-ra20actc	429	25	to	to	IN
cord-329515-ra20actc	429	26	a	a	DT
cord-329515-ra20actc	429	27	circulatory	circulatory	JJ
cord-329515-ra20actc	429	28	shock	shock	NN
cord-329515-ra20actc	429	29	resuscitation	resuscitation	NN
cord-329515-ra20actc	429	30	protein	protein	NN
cord-329515-ra20actc	429	31	Signals	signal	NNS
cord-329515-ra20actc	429	32	for	for	IN
cord-329515-ra20actc	429	33	retention	retention	NN
cord-329515-ra20actc	429	34	of	of	IN
cord-329515-ra20actc	429	35	transmembrane	transmembrane	JJ
cord-329515-ra20actc	429	36	proteins	protein	NNS
cord-329515-ra20actc	429	37	in	in	IN
cord-329515-ra20actc	429	38	the	the	DT
cord-329515-ra20actc	429	39	endoplasmic	endoplasmic	NN
cord-329515-ra20actc	429	40	reticulum	reticulum	NN
cord-329515-ra20actc	429	41	studies	study	NNS
cord-329515-ra20actc	429	42	with	with	IN
cord-329515-ra20actc	429	43	CIM	CIM	NNP
cord-329515-ra20actc	429	44	truncation	truncation	NN
cord-329515-ra20actc	429	45	mutants	mutant	NNS
cord-329515-ra20actc	429	46	A	a	DT
cord-329515-ra20actc	429	47	Golgi	Golgi	NNP
cord-329515-ra20actc	429	48	retention	retention	NN
cord-329515-ra20actc	429	49	signal	signal	NN
cord-329515-ra20actc	429	50	in	in	IN
cord-329515-ra20actc	429	51	a	a	DT
cord-329515-ra20actc	429	52	membrane	membrane	NN
cord-329515-ra20actc	429	53	-	-	HYPH
cord-329515-ra20actc	429	54	spanning	span	VBG
cord-329515-ra20actc	429	55	domain	domain	NN
cord-329515-ra20actc	429	56	of	of	IN
cord-329515-ra20actc	429	57	coronavirus	coronavirus	NN
cord-329515-ra20actc	429	58	El	El	NNP
cord-329515-ra20actc	429	59	protein	protein	NN
cord-329515-ra20actc	430	1	The	the	DT
cord-329515-ra20actc	430	2	transmembrane	transmembrane	NN
cord-329515-ra20actc	430	3	domain	domain	NN
cord-329515-ra20actc	430	4	of	of	IN
cord-329515-ra20actc	430	5	N	n	NN
cord-329515-ra20actc	430	6	-	-	HYPH
cord-329515-ra20actc	430	7	glucosaminyltransferase	glucosaminyltransferase	NN
cord-329515-ra20actc	431	1	I	-PRON-	PRP
cord-329515-ra20actc	431	2	contains	contain	VBZ
cord-329515-ra20actc	431	3	a	a	DT
cord-329515-ra20actc	431	4	Golgi	Golgi	NNP
cord-329515-ra20actc	431	5	retention	retention	NN
cord-329515-ra20actc	431	6	signal	signal	NN
cord-329515-ra20actc	431	7	Site	site	NN
cord-329515-ra20actc	431	8	of	of	IN
cord-329515-ra20actc	431	9	addition	addition	NN
cord-329515-ra20actc	431	10	of	of	IN
cord-329515-ra20actc	431	11	N	n	NN
cord-329515-ra20actc	431	12	-	-	HYPH
cord-329515-ra20actc	431	13	acetylgalactosamine	acetylgalactosamine	NNP
cord-329515-ra20actc	431	14	to	to	IN
cord-329515-ra20actc	431	15	the	the	DT
cord-329515-ra20actc	431	16	E1	e1	NN
cord-329515-ra20actc	431	17	glycoprotein	glycoprotein	NN
cord-329515-ra20actc	431	18	of	of	IN
cord-329515-ra20actc	431	19	mouse	mouse	NN
cord-329515-ra20actc	431	20	hepatitis	hepatitis	NN
cord-329515-ra20actc	431	21	virus	virus	NN
cord-329515-ra20actc	431	22	-	-	:
cord-329515-ra20actc	431	23	A59	A59	NNP
cord-329515-ra20actc	431	24	Electrophoretic	Electrophoretic	NNP
cord-329515-ra20actc	431	25	transfer	transfer	NN
cord-329515-ra20actc	431	26	of	of	IN
cord-329515-ra20actc	431	27	proteins	protein	NNS
cord-329515-ra20actc	431	28	from	from	IN
cord-329515-ra20actc	431	29	polyacrylamide	polyacrylamide	JJ
cord-329515-ra20actc	431	30	gels	gel	NNS
cord-329515-ra20actc	431	31	to	to	IN
cord-329515-ra20actc	431	32	nitrocellulose	nitrocellulose	NN
cord-329515-ra20actc	431	33	sheets	sheet	NNS
cord-329515-ra20actc	431	34	:	:	:
cord-329515-ra20actc	431	35	procedure	procedure	NN
cord-329515-ra20actc	431	36	and	and	CC
cord-329515-ra20actc	431	37	applications	application	NNS
cord-329515-ra20actc	431	38	Oligomerization	Oligomerization	NNP
cord-329515-ra20actc	431	39	of	of	IN
cord-329515-ra20actc	431	40	a	a	DT
cord-329515-ra20actc	431	41	membrane	membrane	NN
cord-329515-ra20actc	431	42	protein	protein	NN
cord-329515-ra20actc	432	1	correlates	correlate	VBZ
cord-329515-ra20actc	432	2	with	with	IN
cord-329515-ra20actc	432	3	its	-PRON-	PRP$
cord-329515-ra20actc	432	4	retention	retention	NN
cord-329515-ra20actc	432	5	in	in	IN
cord-329515-ra20actc	432	6	the	the	DT
cord-329515-ra20actc	432	7	Golgi	Golgi	NNP
cord-329515-ra20actc	432	8	complex	complex	NN
cord-329515-ra20actc	432	9	A	a	DT
cord-329515-ra20actc	432	10	method	method	NN
cord-329515-ra20actc	432	11	for	for	IN
cord-329515-ra20actc	432	12	the	the	DT
cord-329515-ra20actc	432	13	quantitative	quantitative	JJ
cord-329515-ra20actc	432	14	recovery	recovery	NN
cord-329515-ra20actc	432	15	of	of	IN
cord-329515-ra20actc	432	16	protein	protein	NN
cord-329515-ra20actc	432	17	in	in	IN
cord-329515-ra20actc	432	18	dilute	dilute	JJ
cord-329515-ra20actc	432	19	solution	solution	NN
cord-329515-ra20actc	432	20	in	in	IN
cord-329515-ra20actc	432	21	the	the	DT
cord-329515-ra20actc	432	22	presence	presence	NN
cord-329515-ra20actc	432	23	of	of	IN
cord-329515-ra20actc	432	24	detergents	detergent	NNS
cord-329515-ra20actc	432	25	and	and	CC
cord-329515-ra20actc	432	26	lipids	lipid	NNS
cord-329515-ra20actc	433	1	The	the	DT
cord-329515-ra20actc	433	2	rate	rate	NN
cord-329515-ra20actc	433	3	of	of	IN
cord-329515-ra20actc	433	4	bulk	bulk	JJ
cord-329515-ra20actc	433	5	flow	flow	NN
cord-329515-ra20actc	433	6	from	from	IN
cord-329515-ra20actc	433	7	the	the	DT
cord-329515-ra20actc	433	8	ER	ER	NNP
cord-329515-ra20actc	433	9	to	to	IN
cord-329515-ra20actc	433	10	the	the	DT
cord-329515-ra20actc	433	11	cell	cell	NN
cord-329515-ra20actc	433	12	surface	surface	NN
cord-329515-ra20actc	434	1	The	the	DT
cord-329515-ra20actc	434	2	SXYQRL	SXYQRL	NNP
cord-329515-ra20actc	434	3	sequence	sequence	NN
cord-329515-ra20actc	434	4	in	in	IN
cord-329515-ra20actc	434	5	the	the	DT
cord-329515-ra20actc	434	6	cytoplasmic	cytoplasmic	JJ
cord-329515-ra20actc	434	7	domain	domain	NN
cord-329515-ra20actc	434	8	of	of	IN
cord-329515-ra20actc	434	9	TGN38	TGN38	NNP
cord-329515-ra20actc	434	10	plays	play	VBZ
cord-329515-ra20actc	434	11	a	a	DT
cord-329515-ra20actc	434	12	major	major	JJ
cord-329515-ra20actc	434	13	role	role	NN
cord-329515-ra20actc	434	14	in	in	IN
cord-329515-ra20actc	434	15	trans	trans	NNP
cord-329515-ra20actc	434	16	-	-	NNP
cord-329515-ra20actc	434	17	Golgi	Golgi	NNP
cord-329515-ra20actc	434	18	network	network	NN
cord-329515-ra20actc	434	19	localization	localization	NN
cord-329515-ra20actc	434	20	We	-PRON-	PRP
cord-329515-ra20actc	434	21	thank	thank	VBP
cord-329515-ra20actc	434	22	Dr.	Dr.	NNP
cord-329515-ra20actc	434	23	Y.	Y.	NNP
cord-329515-ra20actc	434	24	Ikehara	Ikehara	NNP
cord-329515-ra20actc	434	25	(	(	-LRB-
cord-329515-ra20actc	434	26	Fukuoka	Fukuoka	NNP
cord-329515-ra20actc	434	27	University	University	NNP
cord-329515-ra20actc	434	28	,	,	,
cord-329515-ra20actc	434	29	Fukuoka	Fukuoka	NNP
cord-329515-ra20actc	434	30	,	,	,
cord-329515-ra20actc	434	31	Japan	Japan	NNP
cord-329515-ra20actc	434	32	)	)	-RRB-
cord-329515-ra20actc	434	33	for	for	IN
cord-329515-ra20actc	434	34	kindly	kindly	RB
cord-329515-ra20actc	434	35	providing	provide	VBG
cord-329515-ra20actc	434	36	us	-PRON-	PRP
cord-329515-ra20actc	434	37	with	with	IN
cord-329515-ra20actc	434	38	a	a	DT
cord-329515-ra20actc	434	39	eDNA	edna	JJ
cord-329515-ra20actc	434	40	encoding	encode	VBG
cord-329515-ra20actc	434	41	human	human	JJ
cord-329515-ra20actc	434	42	DPPIV	DPPIV	NNP
cord-329515-ra20actc	434	43	;	;	:
cord-329515-ra20actc	434	44	and	and	CC
cord-329515-ra20actc	434	45	members	member	NNS
cord-329515-ra20actc	434	46	of	of	IN
cord-329515-ra20actc	434	47	the	the	DT
cord-329515-ra20actc	434	48	Kornfeld	Kornfeld	NNP
cord-329515-ra20actc	434	49	laboratory	laboratory	NN
cord-329515-ra20actc	434	50	for	for	IN
cord-329515-ra20actc	434	51	critical	critical	JJ
cord-329515-ra20actc	434	52	reading	reading	NN
cord-329515-ra20actc	434	53	of	of	IN
cord-329515-ra20actc	434	54	the	the	DT
cord-329515-ra20actc	434	55	manuscript	manuscript	NN
cord-329515-ra20actc	434	56	.	.	.
cord-329515-ra20actc	435	1	This	this	DT
cord-329515-ra20actc	435	2	work	work	NN
cord-329515-ra20actc	435	3	was	be	VBD
cord-329515-ra20actc	435	4	supported	support	VBN
cord-329515-ra20actc	435	5	by	by	IN
cord-329515-ra20actc	435	6	United	United	NNP
cord-329515-ra20actc	435	7	States	States	NNP
cord-329515-ra20actc	435	8	Public	Public	NNP
cord-329515-ra20actc	435	9	Service	Service	NNP
cord-329515-ra20actc	435	10	grant	grant	NN
cord-329515-ra20actc	435	11	CA08759	CA08759	NNP
cord-329515-ra20actc	435	12	.	.	.
cord-329515-ra20actc	436	1	J.	J.	NNP
cord-329515-ra20actc	436	2	Rohrer	Rohrer	NNP
cord-329515-ra20actc	436	3	was	be	VBD
cord-329515-ra20actc	436	4	the	the	DT
cord-329515-ra20actc	436	5	recipient	recipient	NN
cord-329515-ra20actc	436	6	of	of	IN
cord-329515-ra20actc	436	7	a	a	DT
cord-329515-ra20actc	436	8	Damon	Damon	NNP
cord-329515-ra20actc	436	9	Runyon	Runyon	NNP
cord-329515-ra20actc	436	10	-	-	HYPH
cord-329515-ra20actc	436	11	Walter	Walter	NNP
cord-329515-ra20actc	436	12	Winchell	Winchell	NNP
cord-329515-ra20actc	436	13	cancer	cancer	NN
cord-329515-ra20actc	436	14	postdoctoral	postdoctoral	JJ
cord-329515-ra20actc	436	15	fellowship	fellowship	NN
cord-329515-ra20actc	436	16	.	.	.
cord-329515-ra20actc	437	1	A.	A.	NNP
cord-329515-ra20actc	437	2	Sehweizer	Sehweizer	NNP
cord-329515-ra20actc	437	3	was	be	VBD
cord-329515-ra20actc	437	4	supported	support	VBN
cord-329515-ra20actc	437	5	by	by	IN
cord-329515-ra20actc	437	6	the	the	DT
cord-329515-ra20actc	437	7	Swiss	Swiss	NNP
cord-329515-ra20actc	437	8	National	National	NNP
cord-329515-ra20actc	437	9	Science	Science	NNP
cord-329515-ra20actc	437	10	Foundation	Foundation	NNP
cord-329515-ra20actc	437	11	,	,	,
cord-329515-ra20actc	437	12	the	the	DT
cord-329515-ra20actc	437	13	Ciba	Ciba	NNP
cord-329515-ra20actc	437	14	-	-	HYPH
cord-329515-ra20actc	437	15	Geigy	Geigy	NNP
cord-329515-ra20actc	437	16	Jubiliiumsstittung	Jubiliiumsstittung	NNP
cord-329515-ra20actc	437	17	,	,	,
cord-329515-ra20actc	437	18	and	and	CC
cord-329515-ra20actc	437	19	a	a	DT
cord-329515-ra20actc	437	20	W.	W.	NNP
cord-329515-ra20actc	437	21	M.	M.	NNP
cord-329515-ra20actc	437	22	Keck	Keck	NNP
cord-329515-ra20actc	437	23	fellowship	fellowship	NN
cord-329515-ra20actc	437	24	.	.	.
cord-329515-ra20actc	438	1	Received	receive	VBN
cord-329515-ra20actc	438	2	for	for	IN
cord-329515-ra20actc	438	3	publication	publication	NN
cord-329515-ra20actc	438	4	3	3	CD
cord-329515-ra20actc	438	5	February	February	NNP
cord-329515-ra20actc	438	6	1994	1994	CD
cord-329515-ra20actc	438	7	and	and	CC
cord-329515-ra20actc	438	8	in	in	IN
cord-329515-ra20actc	438	9	revised	revise	VBN
cord-329515-ra20actc	438	10	form	form	NN
cord-329515-ra20actc	438	11	4	4	CD
cord-329515-ra20actc	438	12	April	April	NNP
cord-329515-ra20actc	438	13	1994	1994	CD
cord-329515-ra20actc	438	14	.	.	.