id	sid	tid	token	lemma	pos
cord-271501-yjobthaj	1	1	key	key	NNP
cord-271501-yjobthaj	1	2	:	:	:
cord-271501-yjobthaj	1	3	cord-271501-yjobthaj	cord-271501-yjobthaj	XX
cord-271501-yjobthaj	2	1	authors	author	NNS
cord-271501-yjobthaj	2	2	:	:	:
cord-271501-yjobthaj	2	3	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	2	4	,	,	,
cord-271501-yjobthaj	2	5	Carlos	Carlos	NNP
cord-271501-yjobthaj	2	6	B.	B.	NNP
cord-271501-yjobthaj	2	7	title	title	NN
cord-271501-yjobthaj	2	8	:	:	:
cord-271501-yjobthaj	2	9	Transporters	transporter	NNS
cord-271501-yjobthaj	2	10	of	of	IN
cord-271501-yjobthaj	2	11	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	2	12	sugars	sugar	NNS
cord-271501-yjobthaj	2	13	,	,	,
cord-271501-yjobthaj	2	14	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	2	15	sulfate	sulfate	NN
cord-271501-yjobthaj	2	16	and	and	CC
cord-271501-yjobthaj	2	17	ATP	ATP	NNP
cord-271501-yjobthaj	2	18	in	in	IN
cord-271501-yjobthaj	2	19	the	the	DT
cord-271501-yjobthaj	2	20	Golgi	Golgi	NNP
cord-271501-yjobthaj	2	21	apparatus	apparatus	NN
cord-271501-yjobthaj	2	22	membrane	membrane	NN
cord-271501-yjobthaj	2	23	:	:	:
cord-271501-yjobthaj	3	1	Where	where	WRB
cord-271501-yjobthaj	3	2	next	next	JJ
cord-271501-yjobthaj	3	3	?	?	.
cord-271501-yjobthaj	4	1	date	date	NN
cord-271501-yjobthaj	4	2	:	:	:
cord-271501-yjobthaj	4	3	1997	1997	CD
cord-271501-yjobthaj	4	4	-	-	SYM
cord-271501-yjobthaj	4	5	02	02	CD
cord-271501-yjobthaj	4	6	-	-	SYM
cord-271501-yjobthaj	4	7	17	17	CD
cord-271501-yjobthaj	4	8	journal	journal	NN
cord-271501-yjobthaj	4	9	:	:	:
cord-271501-yjobthaj	5	1	Glycobiology	Glycobiology	NNP
cord-271501-yjobthaj	5	2	DOI	DOI	NNP
cord-271501-yjobthaj	5	3	:	:	:
cord-271501-yjobthaj	6	1	10.1093/	10.1093/	NNP
cord-271501-yjobthaj	7	1	glycob/7.2.169	glycob/7.2.169	NNP
cord-271501-yjobthaj	7	2	sha	sha	NNP
cord-271501-yjobthaj	7	3	:	:	:
cord-271501-yjobthaj	7	4	8fbb6f35f20ea8e4a2cb629d883216557f3aa4d0	8fbb6f35f20ea8e4a2cb629d883216557f3aa4d0	NNP
cord-271501-yjobthaj	7	5	doc_id	doc_id	CD
cord-271501-yjobthaj	7	6	:	:	:
cord-271501-yjobthaj	7	7	271501	271501	CD
cord-271501-yjobthaj	8	1	cord_uid	cord_uid	NN
cord-271501-yjobthaj	8	2	:	:	:
cord-271501-yjobthaj	9	1	yjobthaj	yjobthaj	NNP
cord-271501-yjobthaj	10	1	nan	nan	NNP
cord-271501-yjobthaj	11	1	The	the	DT
cord-271501-yjobthaj	11	2	complete	complete	JJ
cord-271501-yjobthaj	11	3	sequencing	sequencing	NN
cord-271501-yjobthaj	11	4	of	of	IN
cord-271501-yjobthaj	11	5	the	the	DT
cord-271501-yjobthaj	11	6	human	human	JJ
cord-271501-yjobthaj	11	7	genome	genome	NN
cord-271501-yjobthaj	11	8	is	be	VBZ
cord-271501-yjobthaj	11	9	underway	underway	JJ
cord-271501-yjobthaj	11	10	while	while	IN
cord-271501-yjobthaj	11	11	that	that	DT
cord-271501-yjobthaj	11	12	of	of	IN
cord-271501-yjobthaj	11	13	S.cerevisiae	S.cerevisiae	NNS
cord-271501-yjobthaj	11	14	and	and	CC
cord-271501-yjobthaj	11	15	C.elegans	c.elegan	NNS
cord-271501-yjobthaj	11	16	has	have	VBZ
cord-271501-yjobthaj	11	17	been	be	VBN
cord-271501-yjobthaj	11	18	completed	complete	VBN
cord-271501-yjobthaj	11	19	.	.	.
cord-271501-yjobthaj	12	1	This	this	DT
cord-271501-yjobthaj	12	2	and	and	CC
cord-271501-yjobthaj	12	3	the	the	DT
cord-271501-yjobthaj	12	4	ongoing	ongoing	JJ
cord-271501-yjobthaj	12	5	cloning	cloning	NN
cord-271501-yjobthaj	12	6	of	of	IN
cord-271501-yjobthaj	12	7	the	the	DT
cord-271501-yjobthaj	12	8	above	above	JJ
cord-271501-yjobthaj	12	9	Golgi	Golgi	NNP
cord-271501-yjobthaj	12	10	membrane	membrane	NN
cord-271501-yjobthaj	12	11	transporters	transporter	NNS
cord-271501-yjobthaj	12	12	raises	raise	VBZ
cord-271501-yjobthaj	12	13	the	the	DT
cord-271501-yjobthaj	12	14	challenge	challenge	NN
cord-271501-yjobthaj	12	15	to	to	TO
cord-271501-yjobthaj	12	16	determine	determine	VB
cord-271501-yjobthaj	12	17	the	the	DT
cord-271501-yjobthaj	12	18	relationship	relationship	NN
cord-271501-yjobthaj	12	19	of	of	IN
cord-271501-yjobthaj	12	20	structural	structural	JJ
cord-271501-yjobthaj	12	21	homologs	homolog	NNS
cord-271501-yjobthaj	12	22	of	of	IN
cord-271501-yjobthaj	12	23	the	the	DT
cord-271501-yjobthaj	12	24	above	above	JJ
cord-271501-yjobthaj	12	25	transporters	transporter	NNS
cord-271501-yjobthaj	12	26	to	to	IN
cord-271501-yjobthaj	12	27	specific	specific	JJ
cord-271501-yjobthaj	12	28	functions	function	NNS
cord-271501-yjobthaj	12	29	.	.	.
cord-271501-yjobthaj	13	1	Do	do	VBP
cord-271501-yjobthaj	13	2	many	many	JJ
cord-271501-yjobthaj	13	3	of	of	IN
cord-271501-yjobthaj	13	4	the	the	DT
cord-271501-yjobthaj	13	5	Golgi	Golgi	NNP
cord-271501-yjobthaj	13	6	membrane	membrane	NN
cord-271501-yjobthaj	13	7	transporters	transporter	NNS
cord-271501-yjobthaj	13	8	have	have	VBP
cord-271501-yjobthaj	13	9	common	common	JJ
cord-271501-yjobthaj	13	10	structural	structural	JJ
cord-271501-yjobthaj	13	11	features	feature	NNS
cord-271501-yjobthaj	13	12	?	?	.
cord-271501-yjobthaj	14	1	Biochemical	biochemical	JJ
cord-271501-yjobthaj	14	2	experiments	experiment	NNS
cord-271501-yjobthaj	14	3	with	with	IN
cord-271501-yjobthaj	14	4	Golgi	Golgi	NNP
cord-271501-yjobthaj	14	5	vesicles	vesicle	NNS
cord-271501-yjobthaj	14	6	have	have	VBP
cord-271501-yjobthaj	14	7	suggested	suggest	VBN
cord-271501-yjobthaj	14	8	that	that	IN
cord-271501-yjobthaj	14	9	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	14	10	sugar	sugar	NN
cord-271501-yjobthaj	14	11	transporters	transporter	NNS
cord-271501-yjobthaj	14	12	have	have	VBP
cord-271501-yjobthaj	14	13	a	a	DT
cord-271501-yjobthaj	14	14	putative	putative	JJ
cord-271501-yjobthaj	14	15	binding	binding	NN
cord-271501-yjobthaj	14	16	motif	motif	NN
cord-271501-yjobthaj	14	17	,	,	,
cord-271501-yjobthaj	14	18	determined	determine	VBN
cord-271501-yjobthaj	14	19	by	by	IN
cord-271501-yjobthaj	14	20	the	the	DT
cord-271501-yjobthaj	14	21	nucleoside	nucleoside	NN
cord-271501-yjobthaj	14	22	base	base	NN
cord-271501-yjobthaj	14	23	(	(	-LRB-
cord-271501-yjobthaj	14	24	Capasso	Capasso	NNP
cord-271501-yjobthaj	14	25	and	and	CC
cord-271501-yjobthaj	14	26	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	14	27	,	,	,
cord-271501-yjobthaj	14	28	1984	1984	CD
cord-271501-yjobthaj	14	29	)	)	-RRB-
cord-271501-yjobthaj	14	30	and	and	CC
cord-271501-yjobthaj	14	31	a	a	DT
cord-271501-yjobthaj	14	32	putative	putative	JJ
cord-271501-yjobthaj	14	33	translocation	translocation	NN
cord-271501-yjobthaj	14	34	motif	motif	NN
cord-271501-yjobthaj	14	35	,	,	,
cord-271501-yjobthaj	14	36	which	which	WDT
cord-271501-yjobthaj	14	37	is	be	VBZ
cord-271501-yjobthaj	14	38	determined	determine	VBN
cord-271501-yjobthaj	14	39	by	by	IN
cord-271501-yjobthaj	14	40	the	the	DT
cord-271501-yjobthaj	14	41	sugar	sugar	NN
cord-271501-yjobthaj	14	42	(	(	-LRB-
cord-271501-yjobthaj	14	43	Capasso	Capasso	NNP
cord-271501-yjobthaj	14	44	and	and	CC
cord-271501-yjobthaj	14	45	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	14	46	,	,	,
cord-271501-yjobthaj	14	47	1984	1984	CD
cord-271501-yjobthaj	14	48	)	)	-RRB-
cord-271501-yjobthaj	14	49	,	,	,
cord-271501-yjobthaj	14	50	that	that	RB
cord-271501-yjobthaj	14	51	is	is	RB
cord-271501-yjobthaj	14	52	,	,	,
cord-271501-yjobthaj	14	53	GMP	GMP	NNP
cord-271501-yjobthaj	14	54	is	be	VBZ
cord-271501-yjobthaj	14	55	a	a	DT
cord-271501-yjobthaj	14	56	competitive	competitive	JJ
cord-271501-yjobthaj	14	57	inhibitor	inhibitor	NN
cord-271501-yjobthaj	14	58	of	of	IN
cord-271501-yjobthaj	14	59	GDP	GDP	NNP
cord-271501-yjobthaj	14	60	-	-	HYPH
cord-271501-yjobthaj	14	61	fucose	fucose	JJ
cord-271501-yjobthaj	14	62	transport	transport	NN
cord-271501-yjobthaj	14	63	in	in	IN
cord-271501-yjobthaj	14	64	mammals	mammal	NNS
cord-271501-yjobthaj	14	65	(	(	-LRB-
cord-271501-yjobthaj	14	66	Sommers	Sommers	NNPS
cord-271501-yjobthaj	14	67	and	and	CC
cord-271501-yjobthaj	14	68	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	14	69	,	,	,
cord-271501-yjobthaj	14	70	1982	1982	CD
cord-271501-yjobthaj	14	71	)	)	-RRB-
cord-271501-yjobthaj	14	72	and	and	CC
cord-271501-yjobthaj	14	73	GDP	gdp	NN
cord-271501-yjobthaj	14	74	-	-	HYPH
cord-271501-yjobthaj	14	75	mannose	mannose	NN
cord-271501-yjobthaj	14	76	transport	transport	NN
cord-271501-yjobthaj	14	77	in	in	IN
cord-271501-yjobthaj	14	78	yeast	yeast	NN
cord-271501-yjobthaj	15	1	(	(	-LRB-
cord-271501-yjobthaj	15	2	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	15	3	et	et	NNP
cord-271501-yjobthaj	15	4	al	al	NNP
cord-271501-yjobthaj	15	5	.	.	NNP
cord-271501-yjobthaj	15	6	,	,	,
cord-271501-yjobthaj	15	7	1989	1989	CD
cord-271501-yjobthaj	15	8	)	)	-RRB-
cord-271501-yjobthaj	15	9	even	even	RB
cord-271501-yjobthaj	15	10	though	though	IN
cord-271501-yjobthaj	15	11	the	the	DT
cord-271501-yjobthaj	15	12	former	former	JJ
cord-271501-yjobthaj	15	13	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	15	14	sugar	sugar	NN
cord-271501-yjobthaj	15	15	does	do	VBZ
cord-271501-yjobthaj	15	16	n't	not	RB
cord-271501-yjobthaj	15	17	cross	cross	VB
cord-271501-yjobthaj	15	18	the	the	DT
cord-271501-yjobthaj	15	19	yeast	yeast	NN
cord-271501-yjobthaj	15	20	Golgi	Golgi	NNP
cord-271501-yjobthaj	15	21	membrane	membrane	NN
cord-271501-yjobthaj	15	22	and	and	CC
cord-271501-yjobthaj	15	23	the	the	DT
cord-271501-yjobthaj	15	24	latter	latter	JJ
cord-271501-yjobthaj	15	25	not	not	RB
cord-271501-yjobthaj	15	26	the	the	DT
cord-271501-yjobthaj	15	27	mammalian	mammalian	JJ
cord-271501-yjobthaj	15	28	one	one	CD
cord-271501-yjobthaj	15	29	.	.	.
cord-271501-yjobthaj	16	1	Transport	transport	NN
cord-271501-yjobthaj	16	2	of	of	IN
cord-271501-yjobthaj	16	3	all	all	DT
cord-271501-yjobthaj	16	4	undine	undine	JJ
cord-271501-yjobthaj	16	5	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	16	6	sugars	sugar	NNS
cord-271501-yjobthaj	16	7	is	be	VBZ
cord-271501-yjobthaj	16	8	inhibited	inhibit	VBN
cord-271501-yjobthaj	16	9	com	com	NN
cord-271501-yjobthaj	16	10	-	-	HYPH
cord-271501-yjobthaj	16	11	petitively	petitively	RB
cord-271501-yjobthaj	16	12	by	by	IN
cord-271501-yjobthaj	16	13	UMP	UMP	NNP
cord-271501-yjobthaj	16	14	while	while	IN
cord-271501-yjobthaj	16	15	the	the	DT
cord-271501-yjobthaj	16	16	sugars	sugar	NNS
cord-271501-yjobthaj	16	17	have	have	VBP
cord-271501-yjobthaj	16	18	no	no	DT
cord-271501-yjobthaj	16	19	effect	effect	NN
cord-271501-yjobthaj	16	20	(	(	-LRB-
cord-271501-yjobthaj	16	21	Capasso	Capasso	NNP
cord-271501-yjobthaj	16	22	and	and	CC
cord-271501-yjobthaj	16	23	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	16	24	,	,	,
cord-271501-yjobthaj	16	25	1984	1984	CD
cord-271501-yjobthaj	16	26	)	)	-RRB-
cord-271501-yjobthaj	16	27	.	.	.
cord-271501-yjobthaj	17	1	UMP	UMP	NNP
cord-271501-yjobthaj	17	2	is	be	VBZ
cord-271501-yjobthaj	17	3	the	the	DT
cord-271501-yjobthaj	17	4	antiporter	antiporter	NN
cord-271501-yjobthaj	17	5	for	for	IN
cord-271501-yjobthaj	17	6	all	all	DT
cord-271501-yjobthaj	17	7	undine	undine	JJ
cord-271501-yjobthaj	17	8	containing	contain	VBG
cord-271501-yjobthaj	17	9	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	17	10	sugars	sugar	NNS
cord-271501-yjobthaj	17	11	(	(	-LRB-
cord-271501-yjobthaj	17	12	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	17	13	and	and	CC
cord-271501-yjobthaj	17	14	Snider	Snider	NNP
cord-271501-yjobthaj	17	15	,	,	,
cord-271501-yjobthaj	17	16	1987	1987	CD
cord-271501-yjobthaj	17	17	;	;	:
cord-271501-yjobthaj	18	1	Waldman	Waldman	NNP
cord-271501-yjobthaj	18	2	and	and	CC
cord-271501-yjobthaj	18	3	Rudnick	Rudnick	NNP
cord-271501-yjobthaj	18	4	,	,	,
cord-271501-yjobthaj	18	5	1990	1990	CD
cord-271501-yjobthaj	18	6	;	;	:
cord-271501-yjobthaj	18	7	Milla	Milla	NNP
cord-271501-yjobthaj	18	8	et	et	NNP
cord-271501-yjobthaj	18	9	al	al	NNP
cord-271501-yjobthaj	18	10	.	.	NNP
cord-271501-yjobthaj	18	11	,	,	,
cord-271501-yjobthaj	18	12	1992	1992	CD
cord-271501-yjobthaj	18	13	)	)	-RRB-
cord-271501-yjobthaj	18	14	;	;	:
cord-271501-yjobthaj	18	15	thus	thus	RB
cord-271501-yjobthaj	18	16	,	,	,
cord-271501-yjobthaj	18	17	one	one	PRP
cord-271501-yjobthaj	18	18	would	would	MD
cord-271501-yjobthaj	18	19	expect	expect	VB
cord-271501-yjobthaj	18	20	all	all	PDT
cord-271501-yjobthaj	18	21	these	these	DT
cord-271501-yjobthaj	18	22	uridine	uridine	NN
cord-271501-yjobthaj	18	23	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	18	24	sugar	sugar	NN
cord-271501-yjobthaj	18	25	transporters	transporter	NNS
cord-271501-yjobthaj	18	26	to	to	TO
cord-271501-yjobthaj	18	27	have	have	VB
cord-271501-yjobthaj	18	28	common	common	JJ
cord-271501-yjobthaj	18	29	structural	structural	JJ
cord-271501-yjobthaj	18	30	features	feature	NNS
cord-271501-yjobthaj	18	31	facing	face	VBG
cord-271501-yjobthaj	18	32	the	the	DT
cord-271501-yjobthaj	18	33	lumenal	lumenal	JJ
cord-271501-yjobthaj	18	34	and	and	CC
cord-271501-yjobthaj	18	35	cytosolic	cytosolic	JJ
cord-271501-yjobthaj	18	36	side	side	NN
cord-271501-yjobthaj	18	37	of	of	IN
cord-271501-yjobthaj	18	38	the	the	DT
cord-271501-yjobthaj	18	39	membrane	membrane	NN
cord-271501-yjobthaj	18	40	.	.	.
cord-271501-yjobthaj	19	1	By	by	IN
cord-271501-yjobthaj	19	2	analogy	analogy	NN
cord-271501-yjobthaj	19	3	to	to	IN
cord-271501-yjobthaj	19	4	the	the	DT
cord-271501-yjobthaj	19	5	ATP	ATP	NNP
cord-271501-yjobthaj	19	6	/	/	SYM
cord-271501-yjobthaj	19	7	ADP	ADP	NNP
cord-271501-yjobthaj	19	8	transporter	transporter	NN
cord-271501-yjobthaj	19	9	of	of	IN
cord-271501-yjobthaj	19	10	mitochondria	mitochondrion	NNS
cord-271501-yjobthaj	19	11	(	(	-LRB-
cord-271501-yjobthaj	19	12	Klingenberg	Klingenberg	NNP
cord-271501-yjobthaj	19	13	,	,	,
cord-271501-yjobthaj	19	14	1993	1993	CD
cord-271501-yjobthaj	19	15	)	)	-RRB-
cord-271501-yjobthaj	19	16	,	,	,
cord-271501-yjobthaj	19	17	one	one	PRP
cord-271501-yjobthaj	19	18	would	would	MD
cord-271501-yjobthaj	19	19	expect	expect	VB
cord-271501-yjobthaj	19	20	the	the	DT
cord-271501-yjobthaj	19	21	affinity	affinity	NN
cord-271501-yjobthaj	19	22	for	for	IN
cord-271501-yjobthaj	19	23	the	the	DT
cord-271501-yjobthaj	19	24	corresponding	corresponding	JJ
cord-271501-yjobthaj	19	25	nucleoside	nucleoside	NN
cord-271501-yjobthaj	19	26	monophosphate	monophosphate	NN
cord-271501-yjobthaj	19	27	of	of	IN
cord-271501-yjobthaj	19	28	each	each	DT
cord-271501-yjobthaj	19	29	transporter	transporter	NN
cord-271501-yjobthaj	19	30	to	to	TO
cord-271501-yjobthaj	19	31	be	be	VB
cord-271501-yjobthaj	19	32	higher	high	JJR
cord-271501-yjobthaj	19	33	in	in	IN
cord-271501-yjobthaj	19	34	its	-PRON-	PRP$
cord-271501-yjobthaj	19	35	lumenal	lumenal	JJ
cord-271501-yjobthaj	19	36	recognition	recognition	NN
cord-271501-yjobthaj	19	37	domain	domain	NN
cord-271501-yjobthaj	19	38	than	than	IN
cord-271501-yjobthaj	19	39	in	in	IN
cord-271501-yjobthaj	19	40	its	-PRON-	PRP$
cord-271501-yjobthaj	19	41	cytosolic	cytosolic	JJ
cord-271501-yjobthaj	19	42	one	one	NN
cord-271501-yjobthaj	19	43	and	and	CC
cord-271501-yjobthaj	19	44	the	the	DT
cord-271501-yjobthaj	19	45	opposite	opposite	NN
cord-271501-yjobthaj	19	46	for	for	IN
cord-271501-yjobthaj	19	47	the	the	DT
cord-271501-yjobthaj	19	48	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	19	49	derivative	derivative	NN
cord-271501-yjobthaj	19	50	.	.	.
cord-271501-yjobthaj	20	1	Hydrophobicity	hydrophobicity	NN
cord-271501-yjobthaj	20	2	plots	plot	NNS
cord-271501-yjobthaj	20	3	and	and	CC
cord-271501-yjobthaj	20	4	different	different	JJ
cord-271501-yjobthaj	20	5	algorithms	algorithm	NNS
cord-271501-yjobthaj	20	6	for	for	IN
cord-271501-yjobthaj	20	7	the	the	DT
cord-271501-yjobthaj	20	8	putative	putative	JJ
cord-271501-yjobthaj	20	9	orientation	orientation	NN
cord-271501-yjobthaj	20	10	of	of	IN
cord-271501-yjobthaj	20	11	membrane	membrane	NN
cord-271501-yjobthaj	20	12	proteins	protein	NNS
cord-271501-yjobthaj	20	13	provide	provide	VBP
cord-271501-yjobthaj	20	14	only	only	RB
cord-271501-yjobthaj	20	15	a	a	DT
cord-271501-yjobthaj	20	16	beginning	beginning	NN
cord-271501-yjobthaj	20	17	hypothesis	hypothesis	NN
cord-271501-yjobthaj	20	18	for	for	IN
cord-271501-yjobthaj	20	19	the	the	DT
cord-271501-yjobthaj	20	20	topography	topography	NN
cord-271501-yjobthaj	20	21	of	of	IN
cord-271501-yjobthaj	20	22	such	such	JJ
cord-271501-yjobthaj	20	23	proteins	protein	NNS
cord-271501-yjobthaj	20	24	;	;	:
cord-271501-yjobthaj	20	25	thus	thus	RB
cord-271501-yjobthaj	20	26	,	,	,
cord-271501-yjobthaj	20	27	the	the	DT
cord-271501-yjobthaj	20	28	number	number	NN
cord-271501-yjobthaj	20	29	of	of	IN
cord-271501-yjobthaj	20	30	transmembrane	transmembrane	NN
cord-271501-yjobthaj	20	31	spanning	span	VBG
cord-271501-yjobthaj	20	32	domains	domain	NNS
cord-271501-yjobthaj	20	33	and	and	CC
cord-271501-yjobthaj	20	34	regions	region	NNS
cord-271501-yjobthaj	20	35	,	,	,
cord-271501-yjobthaj	20	36	including	include	VBG
cord-271501-yjobthaj	20	37	the	the	DT
cord-271501-yjobthaj	20	38	amino	amino	NNS
cord-271501-yjobthaj	20	39	and	and	CC
cord-271501-yjobthaj	20	40	carboxy	carboxy	JJ
cord-271501-yjobthaj	20	41	terminus	terminus	NN
cord-271501-yjobthaj	20	42	,	,	,
cord-271501-yjobthaj	20	43	facing	face	VBG
cord-271501-yjobthaj	20	44	the	the	DT
cord-271501-yjobthaj	20	45	cytosol	cytosol	NN
cord-271501-yjobthaj	20	46	or	or	CC
cord-271501-yjobthaj	20	47	the	the	DT
cord-271501-yjobthaj	20	48	lumen	lumen	NN
cord-271501-yjobthaj	20	49	will	will	MD
cord-271501-yjobthaj	20	50	need	need	VB
cord-271501-yjobthaj	20	51	to	to	TO
cord-271501-yjobthaj	20	52	be	be	VB
cord-271501-yjobthaj	20	53	determined	determine	VBN
cord-271501-yjobthaj	20	54	directly	directly	RB
cord-271501-yjobthaj	20	55	.	.	.
cord-271501-yjobthaj	21	1	The	the	DT
cord-271501-yjobthaj	21	2	quaternary	quaternary	JJ
cord-271501-yjobthaj	21	3	structure	structure	NN
cord-271501-yjobthaj	21	4	of	of	IN
cord-271501-yjobthaj	21	5	these	these	DT
cord-271501-yjobthaj	21	6	transporters	transporter	NNS
cord-271501-yjobthaj	21	7	is	be	VBZ
cord-271501-yjobthaj	21	8	important	important	JJ
cord-271501-yjobthaj	21	9	to	to	TO
cord-271501-yjobthaj	21	10	establish	establish	VB
cord-271501-yjobthaj	21	11	:	:	:
cord-271501-yjobthaj	21	12	to	to	TO
cord-271501-yjobthaj	21	13	what	what	WDT
cord-271501-yjobthaj	21	14	extent	extent	NN
cord-271501-yjobthaj	21	15	is	be	VBZ
cord-271501-yjobthaj	21	16	recent	recent	JJ
cord-271501-yjobthaj	21	17	evidence	evidence	NN
cord-271501-yjobthaj	21	18	showing	show	VBG
cord-271501-yjobthaj	21	19	that	that	IN
cord-271501-yjobthaj	21	20	the	the	DT
cord-271501-yjobthaj	21	21	Golgi	Golgi	NNP
cord-271501-yjobthaj	21	22	membrane	membrane	NN
cord-271501-yjobthaj	21	23	PAPS	pap	NNS
cord-271501-yjobthaj	21	24	transporter	transporter	NN
cord-271501-yjobthaj	21	25	is	be	VBZ
cord-271501-yjobthaj	21	26	a	a	DT
cord-271501-yjobthaj	21	27	homodimer	homodimer	JJ
cord-271501-yjobthaj	21	28	(	(	-LRB-
cord-271501-yjobthaj	21	29	Mandon	Mandon	NNP
cord-271501-yjobthaj	21	30	et	et	FW
cord-271501-yjobthaj	21	31	al	al	NNP
cord-271501-yjobthaj	21	32	.	.	NNP
cord-271501-yjobthaj	21	33	,	,	,
cord-271501-yjobthaj	21	34	1994b	1994b	CD
cord-271501-yjobthaj	21	35	)	)	-RRB-
cord-271501-yjobthaj	21	36	,	,	,
cord-271501-yjobthaj	21	37	a	a	DT
cord-271501-yjobthaj	21	38	general	general	JJ
cord-271501-yjobthaj	21	39	feature	feature	NN
cord-271501-yjobthaj	21	40	of	of	IN
cord-271501-yjobthaj	21	41	these	these	DT
cord-271501-yjobthaj	21	42	transporters	transporter	NNS
cord-271501-yjobthaj	21	43	.	.	.
cord-271501-yjobthaj	22	1	Recent	recent	JJ
cord-271501-yjobthaj	22	2	evidence	evidence	NN
cord-271501-yjobthaj	22	3	in	in	IN
cord-271501-yjobthaj	22	4	mammals	mammal	NNS
cord-271501-yjobthaj	22	5	and	and	CC
cord-271501-yjobthaj	22	6	yeast	yeast	NN
cord-271501-yjobthaj	22	7	suggests	suggest	VBZ
cord-271501-yjobthaj	22	8	that	that	IN
cord-271501-yjobthaj	22	9	Golgi	Golgi	NNP
cord-271501-yjobthaj	22	10	membrane	membrane	NN
cord-271501-yjobthaj	22	11	transporters	transporter	NNS
cord-271501-yjobthaj	22	12	play	play	VBP
cord-271501-yjobthaj	22	13	a	a	DT
cord-271501-yjobthaj	22	14	regulatory	regulatory	JJ
cord-271501-yjobthaj	22	15	role	role	NN
cord-271501-yjobthaj	22	16	in	in	IN
cord-271501-yjobthaj	22	17	determining	determine	VBG
cord-271501-yjobthaj	22	18	which	which	WDT
cord-271501-yjobthaj	22	19	macromolecules	macromolecule	NNS
cord-271501-yjobthaj	22	20	undergo	undergo	VBP
cord-271501-yjobthaj	22	21	specific	specific	JJ
cord-271501-yjobthaj	22	22	posttranslational	posttranslational	JJ
cord-271501-yjobthaj	22	23	modifications	modification	NNS
cord-271501-yjobthaj	22	24	in	in	IN
cord-271501-yjobthaj	22	25	the	the	DT
cord-271501-yjobthaj	22	26	lumen	lumen	NN
cord-271501-yjobthaj	22	27	of	of	IN
cord-271501-yjobthaj	22	28	the	the	DT
cord-271501-yjobthaj	22	29	Golgi	Golgi	NNP
cord-271501-yjobthaj	22	30	apparatus	apparatus	NN
cord-271501-yjobthaj	23	1	(	(	-LRB-
cord-271501-yjobthaj	23	2	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	23	3	et	et	NNP
cord-271501-yjobthaj	23	4	al	al	NNP
cord-271501-yjobthaj	23	5	.	.	.
cord-271501-yjobthaj	24	1	,	,	,
cord-271501-yjobthaj	24	2	1993	1993	CD
cord-271501-yjobthaj	24	3	;	;	:
cord-271501-yjobthaj	24	4	Toma	Toma	NNP
cord-271501-yjobthaj	24	5	et	et	NNP
cord-271501-yjobthaj	24	6	al	al	NNP
cord-271501-yjobthaj	24	7	.	.	NNP
cord-271501-yjobthaj	24	8	,	,	,
cord-271501-yjobthaj	24	9	1996	1996	CD
cord-271501-yjobthaj	24	10	)	)	-RRB-
cord-271501-yjobthaj	24	11	.	.	.
cord-271501-yjobthaj	25	1	The	the	DT
cord-271501-yjobthaj	25	2	supply	supply	NN
cord-271501-yjobthaj	25	3	of	of	IN
cord-271501-yjobthaj	25	4	nucleotides	nucleotide	NNS
cord-271501-yjobthaj	25	5	and	and	CC
cord-271501-yjobthaj	25	6	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	25	7	derivatives	derivative	NNS
cord-271501-yjobthaj	25	8	in	in	IN
cord-271501-yjobthaj	25	9	the	the	DT
cord-271501-yjobthaj	25	10	Golgi	Golgi	NNP
cord-271501-yjobthaj	25	11	lumen	lumen	NN
cord-271501-yjobthaj	25	12	is	be	VBZ
cord-271501-yjobthaj	25	13	limiting	limit	VBG
cord-271501-yjobthaj	25	14	under	under	IN
cord-271501-yjobthaj	25	15	physiological	physiological	JJ
cord-271501-yjobthaj	25	16	conditions	condition	NNS
cord-271501-yjobthaj	25	17	thereby	thereby	RB
cord-271501-yjobthaj	25	18	allowing	allow	VBG
cord-271501-yjobthaj	25	19	those	those	DT
cord-271501-yjobthaj	25	20	reactions	reaction	NNS
cord-271501-yjobthaj	25	21	with	with	IN
cord-271501-yjobthaj	25	22	low	low	JJ
cord-271501-yjobthaj	25	23	Kn	Kn	NNP
cord-271501-yjobthaj	25	24	,	,	,
cord-271501-yjobthaj	25	25	values	value	NNS
cord-271501-yjobthaj	25	26	to	to	TO
cord-271501-yjobthaj	25	27	take	take	VB
cord-271501-yjobthaj	25	28	preference	preference	NN
cord-271501-yjobthaj	25	29	over	over	IN
cord-271501-yjobthaj	25	30	those	those	DT
cord-271501-yjobthaj	25	31	with	with	IN
cord-271501-yjobthaj	25	32	higher	high	JJR
cord-271501-yjobthaj	25	33	ones	one	NNS
cord-271501-yjobthaj	25	34	.	.	.
cord-271501-yjobthaj	26	1	An	an	DT
cord-271501-yjobthaj	26	2	open	open	JJ
cord-271501-yjobthaj	26	3	question	question	NN
cord-271501-yjobthaj	26	4	is	be	VBZ
cord-271501-yjobthaj	26	5	whether	whether	IN
cord-271501-yjobthaj	26	6	overexpression	overexpression	NN
cord-271501-yjobthaj	26	7	of	of	IN
cord-271501-yjobthaj	26	8	transporter	transporter	NN
cord-271501-yjobthaj	26	9	proteins	protein	NNS
cord-271501-yjobthaj	26	10	in	in	IN
cord-271501-yjobthaj	26	11	the	the	DT
cord-271501-yjobthaj	26	12	membrane	membrane	NN
cord-271501-yjobthaj	26	13	of	of	IN
cord-271501-yjobthaj	26	14	the	the	DT
cord-271501-yjobthaj	26	15	Golgi	Golgi	NNP
cord-271501-yjobthaj	26	16	apparatus	apparatus	NN
cord-271501-yjobthaj	26	17	will	will	MD
cord-271501-yjobthaj	26	18	affect	affect	VB
cord-271501-yjobthaj	26	19	transport	transport	NN
cord-271501-yjobthaj	26	20	activity	activity	NN
cord-271501-yjobthaj	26	21	.	.	.
cord-271501-yjobthaj	27	1	Can	Can	MD
cord-271501-yjobthaj	27	2	intrinsic	intrinsic	JJ
cord-271501-yjobthaj	27	3	activities	activity	NNS
cord-271501-yjobthaj	27	4	of	of	IN
cord-271501-yjobthaj	27	5	these	these	DT
cord-271501-yjobthaj	27	6	different	different	JJ
cord-271501-yjobthaj	27	7	transporters	transporter	NNS
cord-271501-yjobthaj	27	8	be	be	VB
cord-271501-yjobthaj	27	9	modulated	modulate	VBN
cord-271501-yjobthaj	27	10	by	by	IN
cord-271501-yjobthaj	27	11	different	different	JJ
cord-271501-yjobthaj	27	12	effectors	effector	NNS
cord-271501-yjobthaj	27	13	including	include	VBG
cord-271501-yjobthaj	27	14	cytosolic	cytosolic	JJ
cord-271501-yjobthaj	27	15	and	and	CC
cord-271501-yjobthaj	27	16	lumenal	lumenal	JJ
cord-271501-yjobthaj	27	17	nucleotides	nucleotide	NNS
cord-271501-yjobthaj	27	18	that	that	WDT
cord-271501-yjobthaj	27	19	are	be	VBP
cord-271501-yjobthaj	27	20	known	know	VBN
cord-271501-yjobthaj	27	21	to	to	TO
cord-271501-yjobthaj	27	22	be	be	VB
cord-271501-yjobthaj	27	23	competitive	competitive	JJ
cord-271501-yjobthaj	27	24	inhibitors	inhibitor	NNS
cord-271501-yjobthaj	27	25	of	of	IN
cord-271501-yjobthaj	27	26	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	27	27	sugar	sugar	NN
cord-271501-yjobthaj	27	28	transport	transport	NN
cord-271501-yjobthaj	27	29	(	(	-LRB-
cord-271501-yjobthaj	27	30	Capasso	Capasso	NNP
cord-271501-yjobthaj	27	31	and	and	CC
cord-271501-yjobthaj	27	32	Hirschberg	Hirschberg	NNP
cord-271501-yjobthaj	27	33	,	,	,
cord-271501-yjobthaj	27	34	1984	1984	CD
cord-271501-yjobthaj	27	35	)	)	-RRB-
cord-271501-yjobthaj	27	36	?	?	.
cord-271501-yjobthaj	28	1	Is	be	VBZ
cord-271501-yjobthaj	28	2	the	the	DT
cord-271501-yjobthaj	28	3	expression	expression	NN
cord-271501-yjobthaj	28	4	of	of	IN
cord-271501-yjobthaj	28	5	the	the	DT
cord-271501-yjobthaj	28	6	different	different	JJ
cord-271501-yjobthaj	28	7	transporter	transporter	NN
cord-271501-yjobthaj	28	8	proteins	protein	NNS
cord-271501-yjobthaj	28	9	subject	subject	JJ
cord-271501-yjobthaj	28	10	to	to	IN
cord-271501-yjobthaj	28	11	transcriptional	transcriptional	JJ
cord-271501-yjobthaj	28	12	or	or	CC
cord-271501-yjobthaj	28	13	translational	translational	JJ
cord-271501-yjobthaj	28	14	regulation	regulation	NN
cord-271501-yjobthaj	28	15	during	during	IN
cord-271501-yjobthaj	28	16	different	different	JJ
cord-271501-yjobthaj	28	17	physiological	physiological	JJ
cord-271501-yjobthaj	28	18	conditions	condition	NNS
cord-271501-yjobthaj	28	19	and	and	CC
cord-271501-yjobthaj	28	20	development	development	NN
cord-271501-yjobthaj	28	21	?	?	.
cord-271501-yjobthaj	29	1	Detailed	detailed	JJ
cord-271501-yjobthaj	29	2	functional	functional	JJ
cord-271501-yjobthaj	29	3	studies	study	NNS
cord-271501-yjobthaj	29	4	of	of	IN
cord-271501-yjobthaj	29	5	these	these	DT
cord-271501-yjobthaj	29	6	transporters	transporter	NNS
cord-271501-yjobthaj	29	7	will	will	MD
cord-271501-yjobthaj	29	8	require	require	VB
cord-271501-yjobthaj	29	9	high	high	JJ
cord-271501-yjobthaj	29	10	microgram	microgram	NN
cord-271501-yjobthaj	29	11	amounts	amount	NNS
cord-271501-yjobthaj	29	12	for	for	IN
cord-271501-yjobthaj	29	13	reconstitution	reconstitution	NN
cord-271501-yjobthaj	29	14	into	into	IN
cord-271501-yjobthaj	29	15	liposomes	liposome	NNS
cord-271501-yjobthaj	29	16	.	.	.
cord-271501-yjobthaj	30	1	These	these	DT
cord-271501-yjobthaj	30	2	proteoliposomes	proteoliposome	NNS
cord-271501-yjobthaj	30	3	should	should	MD
cord-271501-yjobthaj	30	4	then	then	RB
cord-271501-yjobthaj	30	5	be	be	VB
cord-271501-yjobthaj	30	6	useful	useful	JJ
cord-271501-yjobthaj	30	7	in	in	IN
cord-271501-yjobthaj	30	8	electrophysiological	electrophysiological	JJ
cord-271501-yjobthaj	30	9	studies	study	NNS
cord-271501-yjobthaj	30	10	analogous	analogous	JJ
cord-271501-yjobthaj	30	11	to	to	IN
cord-271501-yjobthaj	30	12	recent	recent	JJ
cord-271501-yjobthaj	30	13	ones	one	NNS
cord-271501-yjobthaj	30	14	with	with	IN
cord-271501-yjobthaj	30	15	CFTR	CFTR	NNP
cord-271501-yjobthaj	31	1	(	(	-LRB-
cord-271501-yjobthaj	31	2	Bear	Bear	NNP
cord-271501-yjobthaj	31	3	et	et	NNP
cord-271501-yjobthaj	31	4	al	al	NNP
cord-271501-yjobthaj	31	5	.	.	NNP
cord-271501-yjobthaj	31	6	,	,	,
cord-271501-yjobthaj	31	7	1992	1992	CD
cord-271501-yjobthaj	31	8	)	)	-RRB-
cord-271501-yjobthaj	32	1	to	to	TO
cord-271501-yjobthaj	32	2	address	address	VB
cord-271501-yjobthaj	32	3	what	what	WP
cord-271501-yjobthaj	32	4	nucleotide	nucleotide	NN
cord-271501-yjobthaj	32	5	and	and	CC
cord-271501-yjobthaj	32	6	phosphate	phosphate	NN
cord-271501-yjobthaj	32	7	species	specie	NNS
cord-271501-yjobthaj	32	8	cross	cross	VBP
cord-271501-yjobthaj	32	9	the	the	DT
cord-271501-yjobthaj	32	10	membrane	membrane	NN
cord-271501-yjobthaj	32	11	,	,	,
cord-271501-yjobthaj	32	12	what	what	WP
cord-271501-yjobthaj	32	13	their	-PRON-	PRP$
cord-271501-yjobthaj	32	14	charges	charge	NNS
cord-271501-yjobthaj	32	15	are	be	VBP
cord-271501-yjobthaj	32	16	,	,	,
cord-271501-yjobthaj	32	17	and	and	CC
cord-271501-yjobthaj	32	18	to	to	TO
cord-271501-yjobthaj	32	19	study	study	VB
cord-271501-yjobthaj	32	20	the	the	DT
cord-271501-yjobthaj	32	21	possible	possible	JJ
cord-271501-yjobthaj	32	22	existence	existence	NN
cord-271501-yjobthaj	32	23	of	of	IN
cord-271501-yjobthaj	32	24	cotransporters	cotransporter	NNS
cord-271501-yjobthaj	32	25	coupled	couple	VBN
cord-271501-yjobthaj	32	26	to	to	IN
cord-271501-yjobthaj	32	27	the	the	DT
cord-271501-yjobthaj	32	28	antiporters	antiporter	NNS
cord-271501-yjobthaj	32	29	.	.	.
cord-271501-yjobthaj	33	1	A	a	DT
cord-271501-yjobthaj	33	2	combination	combination	NN
cord-271501-yjobthaj	33	3	of	of	IN
cord-271501-yjobthaj	33	4	genetics	genetic	NNS
cord-271501-yjobthaj	33	5	and	and	CC
cord-271501-yjobthaj	33	6	overexpression	overexpression	NN
cord-271501-yjobthaj	33	7	of	of	IN
cord-271501-yjobthaj	33	8	wild	wild	JJ
cord-271501-yjobthaj	33	9	-	-	HYPH
cord-271501-yjobthaj	33	10	type	type	NN
cord-271501-yjobthaj	33	11	and	and	CC
cord-271501-yjobthaj	33	12	mutant	mutant	JJ
cord-271501-yjobthaj	33	13	transporter	transporter	NN
cord-271501-yjobthaj	33	14	proteins	protein	NNS
cord-271501-yjobthaj	33	15	followed	follow	VBN
cord-271501-yjobthaj	33	16	by	by	IN
cord-271501-yjobthaj	33	17	reconstitution	reconstitution	NN
cord-271501-yjobthaj	33	18	into	into	IN
cord-271501-yjobthaj	33	19	liposomes	liposome	NNS
cord-271501-yjobthaj	33	20	should	should	MD
cord-271501-yjobthaj	33	21	allow	allow	VB
cord-271501-yjobthaj	33	22	determination	determination	NN
cord-271501-yjobthaj	33	23	of	of	IN
cord-271501-yjobthaj	33	24	structural	structural	JJ
cord-271501-yjobthaj	33	25	motifs	motif	NNS
cord-271501-yjobthaj	33	26	required	require	VBN
cord-271501-yjobthaj	33	27	for	for	IN
cord-271501-yjobthaj	33	28	membrane	membrane	NN
cord-271501-yjobthaj	33	29	insertion	insertion	NN
cord-271501-yjobthaj	33	30	,	,	,
cord-271501-yjobthaj	33	31	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	33	32	recognition	recognition	NN
cord-271501-yjobthaj	33	33	,	,	,
cord-271501-yjobthaj	33	34	and	and	CC
cord-271501-yjobthaj	33	35	specific	specific	JJ
cord-271501-yjobthaj	33	36	sugar	sugar	NN
cord-271501-yjobthaj	33	37	translocation	translocation	NN
cord-271501-yjobthaj	33	38	.	.	.
cord-271501-yjobthaj	34	1	Studies	study	NNS
cord-271501-yjobthaj	34	2	of	of	IN
cord-271501-yjobthaj	34	3	the	the	DT
cord-271501-yjobthaj	34	4	yeast	yeast	NN
cord-271501-yjobthaj	35	1	GDPase	GDPase	NNP
cord-271501-yjobthaj	35	2	,	,	,
cord-271501-yjobthaj	35	3	which	which	WDT
cord-271501-yjobthaj	35	4	plays	play	VBZ
cord-271501-yjobthaj	35	5	a	a	DT
cord-271501-yjobthaj	35	6	pivotal	pivotal	JJ
cord-271501-yjobthaj	35	7	role	role	NN
cord-271501-yjobthaj	35	8	in	in	IN
cord-271501-yjobthaj	35	9	the	the	DT
cord-271501-yjobthaj	35	10	antiport	antiport	NN
cord-271501-yjobthaj	35	11	mechanism	mechanism	NN
cord-271501-yjobthaj	35	12	for	for	IN
cord-271501-yjobthaj	35	13	GDP	gdp	NN
cord-271501-yjobthaj	35	14	-	-	HYPH
cord-271501-yjobthaj	35	15	mannose	mannose	NN
cord-271501-yjobthaj	35	16	entry	entry	NN
cord-271501-yjobthaj	35	17	into	into	IN
cord-271501-yjobthaj	35	18	the	the	DT
cord-271501-yjobthaj	35	19	Golgi	Golgi	NNP
cord-271501-yjobthaj	35	20	lumen	lumen	NN
cord-271501-yjobthaj	35	21	(	(	-LRB-
cord-271501-yjobthaj	35	22	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	35	23	et	et	NNP
cord-271501-yjobthaj	35	24	al	al	NNP
cord-271501-yjobthaj	35	25	.	.	NNP
cord-271501-yjobthaj	35	26	,	,	,
cord-271501-yjobthaj	35	27	1993	1993	CD
cord-271501-yjobthaj	35	28	;	;	:
cord-271501-yjobthaj	35	29	Berninsone	Berninsone	NNP
cord-271501-yjobthaj	35	30	et	et	NNP
cord-271501-yjobthaj	35	31	al	al	NNP
cord-271501-yjobthaj	35	32	.	.	NNP
cord-271501-yjobthaj	35	33	,	,	,
cord-271501-yjobthaj	35	34	1994	1994	CD
cord-271501-yjobthaj	35	35	)	)	-RRB-
cord-271501-yjobthaj	35	36	,	,	,
cord-271501-yjobthaj	35	37	have	have	VBP
cord-271501-yjobthaj	35	38	shown	show	VBN
cord-271501-yjobthaj	35	39	that	that	IN
cord-271501-yjobthaj	35	40	the	the	DT
cord-271501-yjobthaj	35	41	specificity	specificity	NN
cord-271501-yjobthaj	35	42	of	of	IN
cord-271501-yjobthaj	35	43	this	this	DT
cord-271501-yjobthaj	35	44	enzyme	enzyme	NN
cord-271501-yjobthaj	35	45	can	can	MD
cord-271501-yjobthaj	35	46	be	be	VB
cord-271501-yjobthaj	35	47	altered	alter	VBN
cord-271501-yjobthaj	35	48	depending	depend	VBG
cord-271501-yjobthaj	35	49	on	on	IN
cord-271501-yjobthaj	35	50	whether	whether	IN
cord-271501-yjobthaj	35	51	Ca	Ca	NNP
cord-271501-yjobthaj	35	52	or	or	CC
cord-271501-yjobthaj	35	53	Mn	Mn	NNP
cord-271501-yjobthaj	35	54	+2	+2	NNP
cord-271501-yjobthaj	35	55	are	be	VBP
cord-271501-yjobthaj	35	56	added	add	VBN
cord-271501-yjobthaj	35	57	to	to	IN
cord-271501-yjobthaj	35	58	the	the	DT
cord-271501-yjobthaj	35	59	reaction	reaction	NN
cord-271501-yjobthaj	35	60	(	(	-LRB-
cord-271501-yjobthaj	35	61	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	35	62	et	et	NNP
cord-271501-yjobthaj	35	63	al	al	NNP
cord-271501-yjobthaj	35	64	,	,	,
cord-271501-yjobthaj	35	65	1993	1993	CD
cord-271501-yjobthaj	35	66	)	)	-RRB-
cord-271501-yjobthaj	35	67	.	.	.
cord-271501-yjobthaj	36	1	To	to	TO
cord-271501-yjobthaj	36	2	what	what	WDT
cord-271501-yjobthaj	36	3	extent	extent	NN
cord-271501-yjobthaj	36	4	may	may	MD
cord-271501-yjobthaj	36	5	this	this	DT
cord-271501-yjobthaj	36	6	be	be	VB
cord-271501-yjobthaj	36	7	another	another	DT
cord-271501-yjobthaj	36	8	regulatory	regulatory	JJ
cord-271501-yjobthaj	36	9	mechanism	mechanism	NN
cord-271501-yjobthaj	36	10	of	of	IN
cord-271501-yjobthaj	36	11	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	36	12	sugar	sugar	NN
cord-271501-yjobthaj	36	13	transport	transport	NN
cord-271501-yjobthaj	36	14	in	in	IN
cord-271501-yjobthaj	36	15	mammals	mammal	NNS
cord-271501-yjobthaj	36	16	which	which	WDT
cord-271501-yjobthaj	36	17	use	use	VBP
cord-271501-yjobthaj	36	18	uridine	uridine	NN
cord-271501-yjobthaj	36	19	and	and	CC
cord-271501-yjobthaj	36	20	guanosine	guanosine	NN
cord-271501-yjobthaj	36	21	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	36	22	sugars	sugar	NNS
cord-271501-yjobthaj	36	23	?	?	.
cord-271501-yjobthaj	37	1	Genetic	genetic	JJ
cord-271501-yjobthaj	37	2	diseases	disease	NNS
cord-271501-yjobthaj	37	3	affect	affect	VBP
cord-271501-yjobthaj	37	4	transport	transport	NN
cord-271501-yjobthaj	37	5	of	of	IN
cord-271501-yjobthaj	37	6	sugars	sugar	NNS
cord-271501-yjobthaj	37	7	and	and	CC
cord-271501-yjobthaj	37	8	amino	amino	JJ
cord-271501-yjobthaj	37	9	acids	acid	NNS
cord-271501-yjobthaj	37	10	in	in	IN
cord-271501-yjobthaj	37	11	membranes	membrane	NNS
cord-271501-yjobthaj	37	12	of	of	IN
cord-271501-yjobthaj	37	13	lysosomes	lysosome	NNS
cord-271501-yjobthaj	37	14	(	(	-LRB-
cord-271501-yjobthaj	37	15	Gahl	Gahl	NNP
cord-271501-yjobthaj	37	16	et	et	FW
cord-271501-yjobthaj	37	17	al	al	NNP
cord-271501-yjobthaj	37	18	.	.	.
cord-271501-yjobthaj	38	1	,	,	,
cord-271501-yjobthaj	38	2	1982	1982	CD
cord-271501-yjobthaj	38	3	;	;	:
cord-271501-yjobthaj	38	4	Rosenblatt	Rosenblatt	NNP
cord-271501-yjobthaj	38	5	et	et	NNP
cord-271501-yjobthaj	38	6	al	al	NNP
cord-271501-yjobthaj	38	7	,	,	,
cord-271501-yjobthaj	38	8	1985	1985	CD
cord-271501-yjobthaj	38	9	;	;	:
cord-271501-yjobthaj	38	10	Mancini	Mancini	NNP
cord-271501-yjobthaj	38	11	et	et	NNP
cord-271501-yjobthaj	38	12	al	al	NNP
cord-271501-yjobthaj	38	13	.	.	NNP
cord-271501-yjobthaj	38	14	,	,	,
cord-271501-yjobthaj	38	15	1989	1989	CD
cord-271501-yjobthaj	38	16	;	;	:
cord-271501-yjobthaj	39	1	Tietze	Tietze	NNP
cord-271501-yjobthaj	39	2	et	et	FW
cord-271501-yjobthaj	39	3	al	al	NNP
cord-271501-yjobthaj	39	4	.	.	NNP
cord-271501-yjobthaj	39	5	,	,	,
cord-271501-yjobthaj	39	6	1989	1989	CD
cord-271501-yjobthaj	39	7	)	)	-RRB-
cord-271501-yjobthaj	39	8	.	.	.
cord-271501-yjobthaj	40	1	Are	be	VBP
cord-271501-yjobthaj	40	2	there	there	EX
cord-271501-yjobthaj	40	3	diseases	disease	NNS
cord-271501-yjobthaj	40	4	related	relate	VBN
cord-271501-yjobthaj	40	5	to	to	IN
cord-271501-yjobthaj	40	6	the	the	DT
cord-271501-yjobthaj	40	7	above	above	JJ
cord-271501-yjobthaj	40	8	Golgi	Golgi	NNP
cord-271501-yjobthaj	40	9	membrane	membrane	NN
cord-271501-yjobthaj	40	10	transporters	transporter	NNS
cord-271501-yjobthaj	40	11	?	?	.
cord-271501-yjobthaj	41	1	One	one	PRP
cord-271501-yjobthaj	41	2	would	would	MD
cord-271501-yjobthaj	41	3	expect	expect	VB
cord-271501-yjobthaj	41	4	mammalian	mammalian	JJ
cord-271501-yjobthaj	41	5	homozygotes	homozygote	NNS
cord-271501-yjobthaj	41	6	in	in	IN
cord-271501-yjobthaj	41	7	some	some	DT
cord-271501-yjobthaj	41	8	Golgi	Golgi	NNP
cord-271501-yjobthaj	41	9	transporter	transporter	NN
cord-271501-yjobthaj	41	10	mutations	mutation	NNS
cord-271501-yjobthaj	41	11	to	to	TO
cord-271501-yjobthaj	41	12	be	be	VB
cord-271501-yjobthaj	41	13	lethal	lethal	JJ
cord-271501-yjobthaj	41	14	,	,	,
cord-271501-yjobthaj	41	15	as	as	IN
cord-271501-yjobthaj	41	16	many	many	JJ
cord-271501-yjobthaj	41	17	transporters	transporter	NNS
cord-271501-yjobthaj	41	18	are	be	VBP
cord-271501-yjobthaj	41	19	highly	highly	RB
cord-271501-yjobthaj	41	20	specific	specific	JJ
cord-271501-yjobthaj	41	21	and	and	CC
cord-271501-yjobthaj	41	22	gene	gene	NN
cord-271501-yjobthaj	41	23	disruptions	disruption	NNS
cord-271501-yjobthaj	41	24	of	of	IN
cord-271501-yjobthaj	41	25	glycosyltransferases	glycosyltransferase	NNS
cord-271501-yjobthaj	41	26	acting	act	VBG
cord-271501-yjobthaj	41	27	downstream	downstream	RB
cord-271501-yjobthaj	41	28	from	from	IN
cord-271501-yjobthaj	41	29	these	these	DT
cord-271501-yjobthaj	41	30	transporters	transporter	NNS
cord-271501-yjobthaj	41	31	were	be	VBD
cord-271501-yjobthaj	41	32	found	find	VBN
cord-271501-yjobthaj	41	33	to	to	TO
cord-271501-yjobthaj	41	34	be	be	VB
cord-271501-yjobthaj	41	35	so	so	RB
cord-271501-yjobthaj	41	36	,	,	,
cord-271501-yjobthaj	41	37	that	that	RB
cord-271501-yjobthaj	41	38	is	is	RB
cord-271501-yjobthaj	41	39	,	,	,
cord-271501-yjobthaj	41	40	N	N	NNP
cord-271501-yjobthaj	41	41	-	-	HYPH
cord-271501-yjobthaj	41	42	acetylglucosaminyltransferase	acetylglucosaminyltransferase	NNP
cord-271501-yjobthaj	41	43	I	-PRON-	PRP
cord-271501-yjobthaj	41	44	(	(	-LRB-
cord-271501-yjobthaj	41	45	Ioffe	Ioffe	NNP
cord-271501-yjobthaj	41	46	and	and	CC
cord-271501-yjobthaj	41	47	Stanley	Stanley	NNP
cord-271501-yjobthaj	41	48	,	,	,
cord-271501-yjobthaj	41	49	1994	1994	CD
cord-271501-yjobthaj	41	50	;	;	:
cord-271501-yjobthaj	41	51	Metzler	Metzler	NNP
cord-271501-yjobthaj	41	52	et	et	NNP
cord-271501-yjobthaj	41	53	al	al	NNP
cord-271501-yjobthaj	41	54	.	.	NNP
cord-271501-yjobthaj	41	55	,	,	,
cord-271501-yjobthaj	41	56	1994	1994	CD
cord-271501-yjobthaj	41	57	)	)	-RRB-
cord-271501-yjobthaj	41	58	.	.	.
cord-271501-yjobthaj	42	1	Nevertheless	nevertheless	RB
cord-271501-yjobthaj	42	2	,	,	,
cord-271501-yjobthaj	42	3	the	the	DT
cord-271501-yjobthaj	42	4	possibility	possibility	NN
cord-271501-yjobthaj	42	5	exists	exist	VBZ
cord-271501-yjobthaj	42	6	that	that	IN
cord-271501-yjobthaj	42	7	during	during	IN
cord-271501-yjobthaj	42	8	pathological	pathological	JJ
cord-271501-yjobthaj	42	9	conditions	condition	NNS
cord-271501-yjobthaj	42	10	,	,	,
cord-271501-yjobthaj	42	11	where	where	WRB
cord-271501-yjobthaj	42	12	some	some	DT
cord-271501-yjobthaj	42	13	of	of	IN
cord-271501-yjobthaj	42	14	these	these	DT
cord-271501-yjobthaj	42	15	transporter	transporter	NN
cord-271501-yjobthaj	42	16	activities	activity	NNS
cord-271501-yjobthaj	42	17	are	be	VBP
cord-271501-yjobthaj	42	18	absent	absent	JJ
cord-271501-yjobthaj	42	19	or	or	CC
cord-271501-yjobthaj	42	20	diminished	diminish	VBN
cord-271501-yjobthaj	42	21	,	,	,
cord-271501-yjobthaj	42	22	other	other	JJ
cord-271501-yjobthaj	42	23	transporters	transporter	NNS
cord-271501-yjobthaj	42	24	may	may	MD
cord-271501-yjobthaj	42	25	partially	partially	RB
cord-271501-yjobthaj	42	26	compensate	compensate	VB
cord-271501-yjobthaj	42	27	for	for	IN
cord-271501-yjobthaj	42	28	lost	lost	JJ
cord-271501-yjobthaj	42	29	function	function	NN
cord-271501-yjobthaj	42	30	,	,	,
cord-271501-yjobthaj	42	31	that	that	RB
cord-271501-yjobthaj	42	32	is	is	RB
cord-271501-yjobthaj	42	33	,	,	,
cord-271501-yjobthaj	42	34	the	the	DT
cord-271501-yjobthaj	42	35	UDP	UDP	NNP
cord-271501-yjobthaj	42	36	-	-	HYPH
cord-271501-yjobthaj	42	37	GlcNAc	glcnac	NN
cord-271501-yjobthaj	42	38	transporter	transporter	NN
cord-271501-yjobthaj	42	39	may	may	MD
cord-271501-yjobthaj	42	40	have	have	VB
cord-271501-yjobthaj	42	41	some	some	DT
cord-271501-yjobthaj	42	42	affinity	affinity	NN
cord-271501-yjobthaj	42	43	,	,	,
cord-271501-yjobthaj	42	44	although	although	IN
cord-271501-yjobthaj	42	45	greatly	greatly	RB
cord-271501-yjobthaj	42	46	diminished	diminish	VBN
cord-271501-yjobthaj	42	47	,	,	,
cord-271501-yjobthaj	42	48	for	for	IN
cord-271501-yjobthaj	42	49	UDP	udp	NN
cord-271501-yjobthaj	42	50	-	-	HYPH
cord-271501-yjobthaj	42	51	GalNAc	galnac	NN
cord-271501-yjobthaj	42	52	transport	transport	NN
cord-271501-yjobthaj	42	53	.	.	.
cord-271501-yjobthaj	43	1	A	a	DT
cord-271501-yjobthaj	43	2	combination	combination	NN
cord-271501-yjobthaj	43	3	of	of	IN
cord-271501-yjobthaj	43	4	genetics	genetics	NN
cord-271501-yjobthaj	43	5	,	,	,
cord-271501-yjobthaj	43	6	gene	gene	NN
cord-271501-yjobthaj	43	7	disruption	disruption	NN
cord-271501-yjobthaj	43	8	,	,	,
cord-271501-yjobthaj	43	9	and	and	CC
cord-271501-yjobthaj	43	10	RNA	RNA	NNP
cord-271501-yjobthaj	43	11	antisense	antisense	NN
cord-271501-yjobthaj	43	12	technology	technology	NN
cord-271501-yjobthaj	43	13	should	should	MD
cord-271501-yjobthaj	43	14	be	be	VB
cord-271501-yjobthaj	43	15	applied	apply	VBN
cord-271501-yjobthaj	43	16	to	to	TO
cord-271501-yjobthaj	43	17	determine	determine	VB
cord-271501-yjobthaj	43	18	the	the	DT
cord-271501-yjobthaj	43	19	possible	possible	JJ
cord-271501-yjobthaj	43	20	role	role	NN
cord-271501-yjobthaj	43	21	of	of	IN
cord-271501-yjobthaj	43	22	these	these	DT
cord-271501-yjobthaj	43	23	transporters	transporter	NNS
cord-271501-yjobthaj	43	24	during	during	IN
cord-271501-yjobthaj	43	25	development	development	NN
cord-271501-yjobthaj	43	26	and	and	CC
cord-271501-yjobthaj	43	27	differentiation	differentiation	NN
cord-271501-yjobthaj	43	28	.	.	.
cord-271501-yjobthaj	44	1	What	what	WDT
cord-271501-yjobthaj	44	2	structural	structural	JJ
cord-271501-yjobthaj	44	3	features	feature	NNS
cord-271501-yjobthaj	44	4	determine	determine	VBP
cord-271501-yjobthaj	44	5	that	that	IN
cord-271501-yjobthaj	44	6	these	these	DT
cord-271501-yjobthaj	44	7	transporters	transporter	NNS
cord-271501-yjobthaj	44	8	become	become	VBP
cord-271501-yjobthaj	44	9	localized	localized	JJ
cord-271501-yjobthaj	44	10	in	in	IN
cord-271501-yjobthaj	44	11	the	the	DT
cord-271501-yjobthaj	44	12	Golgi	Golgi	NNP
cord-271501-yjobthaj	44	13	apparatus	apparatus	NN
cord-271501-yjobthaj	44	14	and/or	and/or	CC
cord-271501-yjobthaj	44	15	the	the	DT
cord-271501-yjobthaj	44	16	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	44	17	reticulum	reticulum	NN
cord-271501-yjobthaj	44	18	and	and	CC
cord-271501-yjobthaj	44	19	not	not	RB
cord-271501-yjobthaj	44	20	another	another	DT
cord-271501-yjobthaj	44	21	organelle	organelle	NN
cord-271501-yjobthaj	44	22	?	?	.
cord-271501-yjobthaj	45	1	To	to	TO
cord-271501-yjobthaj	45	2	what	what	WDT
cord-271501-yjobthaj	45	3	extent	extent	NN
cord-271501-yjobthaj	45	4	will	will	MD
cord-271501-yjobthaj	45	5	transporters	transporter	NNS
cord-271501-yjobthaj	45	6	for	for	IN
cord-271501-yjobthaj	45	7	the	the	DT
cord-271501-yjobthaj	45	8	same	same	JJ
cord-271501-yjobthaj	45	9	solute	solute	NN
cord-271501-yjobthaj	45	10	,	,	,
cord-271501-yjobthaj	45	11	which	which	WDT
cord-271501-yjobthaj	45	12	are	be	VBP
cord-271501-yjobthaj	45	13	localized	localize	VBN
cord-271501-yjobthaj	45	14	in	in	IN
cord-271501-yjobthaj	45	15	different	different	JJ
cord-271501-yjobthaj	45	16	organelles	organelle	NNS
cord-271501-yjobthaj	45	17	,	,	,
cord-271501-yjobthaj	45	18	differ	differ	VBP
cord-271501-yjobthaj	45	19	in	in	IN
cord-271501-yjobthaj	45	20	structure	structure	NN
cord-271501-yjobthaj	45	21	?	?	.
cord-271501-yjobthaj	46	1	ATP	ATP	NNP
cord-271501-yjobthaj	46	2	transporters	transporter	NNS
cord-271501-yjobthaj	46	3	occur	occur	VBP
cord-271501-yjobthaj	46	4	in	in	IN
cord-271501-yjobthaj	46	5	mitochondria	mitochondrion	NNS
cord-271501-yjobthaj	46	6	(	(	-LRB-
cord-271501-yjobthaj	46	7	Klingenberg	Klingenberg	NNP
cord-271501-yjobthaj	46	8	,	,	,
cord-271501-yjobthaj	46	9	1992	1992	CD
cord-271501-yjobthaj	46	10	)	)	-RRB-
cord-271501-yjobthaj	46	11	,	,	,
cord-271501-yjobthaj	46	12	the	the	DT
cord-271501-yjobthaj	46	13	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	46	14	reticulum	reticulum	NN
cord-271501-yjobthaj	46	15	(	(	-LRB-
cord-271501-yjobthaj	46	16	Clairmont	Clairmont	NNP
cord-271501-yjobthaj	46	17	et	et	NNP
cord-271501-yjobthaj	46	18	al	al	NNP
cord-271501-yjobthaj	46	19	.	.	NNP
cord-271501-yjobthaj	46	20	,	,	,
cord-271501-yjobthaj	46	21	1992	1992	CD
cord-271501-yjobthaj	46	22	;	;	:
cord-271501-yjobthaj	46	23	Mayinger	Mayinger	NNP
cord-271501-yjobthaj	46	24	and	and	CC
cord-271501-yjobthaj	46	25	Meyer	Meyer	NNP
cord-271501-yjobthaj	46	26	,	,	,
cord-271501-yjobthaj	46	27	1993	1993	CD
cord-271501-yjobthaj	46	28	;	;	:
cord-271501-yjobthaj	46	29	Mayinger	Mayinger	NNP
cord-271501-yjobthaj	46	30	et	et	NNP
cord-271501-yjobthaj	46	31	al	al	NNP
cord-271501-yjobthaj	46	32	.	.	NNP
cord-271501-yjobthaj	46	33	,	,	,
cord-271501-yjobthaj	46	34	1995	1995	CD
cord-271501-yjobthaj	46	35	)	)	-RRB-
cord-271501-yjobthaj	46	36	,	,	,
cord-271501-yjobthaj	46	37	and	and	CC
cord-271501-yjobthaj	46	38	the	the	DT
cord-271501-yjobthaj	46	39	Golgi	Golgi	NNP
cord-271501-yjobthaj	46	40	apparatus	apparatus	NN
cord-271501-yjobthaj	46	41	(	(	-LRB-
cord-271501-yjobthaj	46	42	Capasso	Capasso	NNP
cord-271501-yjobthaj	46	43	et	et	FW
cord-271501-yjobthaj	46	44	al	al	NNP
cord-271501-yjobthaj	46	45	,	,	,
cord-271501-yjobthaj	46	46	1989	1989	CD
cord-271501-yjobthaj	46	47	):	):	NN
cord-271501-yjobthaj	46	48	all	all	DT
cord-271501-yjobthaj	46	49	of	of	IN
cord-271501-yjobthaj	46	50	them	-PRON-	PRP
cord-271501-yjobthaj	46	51	should	should	MD
cord-271501-yjobthaj	46	52	have	have	VB
cord-271501-yjobthaj	46	53	recognition	recognition	NN
cord-271501-yjobthaj	46	54	features	feature	NNS
cord-271501-yjobthaj	46	55	for	for	IN
cord-271501-yjobthaj	46	56	ATP	ATP	NNP
cord-271501-yjobthaj	46	57	and	and	CC
cord-271501-yjobthaj	46	58	the	the	DT
cord-271501-yjobthaj	46	59	putative	putative	JJ
cord-271501-yjobthaj	46	60	antiporters	antiporter	NNS
cord-271501-yjobthaj	46	61	ADP	ADP	NNP
cord-271501-yjobthaj	46	62	or	or	CC
cord-271501-yjobthaj	46	63	AMP	AMP	NNP
cord-271501-yjobthaj	46	64	,	,	,
cord-271501-yjobthaj	46	65	as	as	RB
cord-271501-yjobthaj	46	66	well	well	RB
cord-271501-yjobthaj	46	67	as	as	IN
cord-271501-yjobthaj	46	68	specific	specific	JJ
cord-271501-yjobthaj	46	69	organellar	organellar	NN
cord-271501-yjobthaj	46	70	targeting	target	VBG
cord-271501-yjobthaj	46	71	features	feature	NNS
cord-271501-yjobthaj	46	72	.	.	.
cord-271501-yjobthaj	47	1	Elucidations	elucidation	NNS
cord-271501-yjobthaj	47	2	of	of	IN
cord-271501-yjobthaj	47	3	them	-PRON-	PRP
cord-271501-yjobthaj	47	4	will	will	MD
cord-271501-yjobthaj	47	5	be	be	VB
cord-271501-yjobthaj	47	6	of	of	IN
cord-271501-yjobthaj	47	7	primary	primary	JJ
cord-271501-yjobthaj	47	8	importance	importance	NN
cord-271501-yjobthaj	47	9	.	.	.
cord-271501-yjobthaj	48	1	The	the	DT
cord-271501-yjobthaj	48	2	sub	sub	JJ
cord-271501-yjobthaj	48	3	-	-	JJ
cord-271501-yjobthaj	48	4	Golgi	golgi	JJ
cord-271501-yjobthaj	48	5	distribution	distribution	NN
cord-271501-yjobthaj	48	6	of	of	IN
cord-271501-yjobthaj	48	7	the	the	DT
cord-271501-yjobthaj	48	8	different	different	JJ
cord-271501-yjobthaj	48	9	transporters	transporter	NNS
cord-271501-yjobthaj	48	10	relative	relative	JJ
cord-271501-yjobthaj	48	11	to	to	IN
cord-271501-yjobthaj	48	12	each	each	DT
cord-271501-yjobthaj	48	13	other	other	JJ
cord-271501-yjobthaj	48	14	and	and	CC
cord-271501-yjobthaj	48	15	to	to	IN
cord-271501-yjobthaj	48	16	transferases	transferase	NNS
cord-271501-yjobthaj	48	17	that	that	WDT
cord-271501-yjobthaj	48	18	use	use	VBP
cord-271501-yjobthaj	48	19	the	the	DT
cord-271501-yjobthaj	48	20	same	same	JJ
cord-271501-yjobthaj	48	21	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	48	22	sugar	sugar	NN
cord-271501-yjobthaj	48	23	as	as	IN
cord-271501-yjobthaj	48	24	substrate	substrate	NN
cord-271501-yjobthaj	48	25	will	will	MD
cord-271501-yjobthaj	48	26	be	be	VB
cord-271501-yjobthaj	48	27	of	of	IN
cord-271501-yjobthaj	48	28	importance	importance	NN
cord-271501-yjobthaj	48	29	.	.	.
cord-271501-yjobthaj	49	1	Will	Will	MD
cord-271501-yjobthaj	49	2	there	there	EX
cord-271501-yjobthaj	49	3	be	be	VB
cord-271501-yjobthaj	49	4	polarization	polarization	NN
cord-271501-yjobthaj	49	5	in	in	IN
cord-271501-yjobthaj	49	6	the	the	DT
cord-271501-yjobthaj	49	7	Golgi	Golgi	NNP
cord-271501-yjobthaj	49	8	apparatus	apparatus	NN
cord-271501-yjobthaj	49	9	of	of	IN
cord-271501-yjobthaj	49	10	these	these	DT
cord-271501-yjobthaj	49	11	transporters	transporter	NNS
cord-271501-yjobthaj	49	12	in	in	IN
cord-271501-yjobthaj	49	13	the	the	DT
cord-271501-yjobthaj	49	14	same	same	JJ
cord-271501-yjobthaj	49	15	general	general	JJ
cord-271501-yjobthaj	49	16	manner	manner	NN
cord-271501-yjobthaj	49	17	as	as	IN
cord-271501-yjobthaj	49	18	glycosyltransferases	glycosyltransferase	NNS
cord-271501-yjobthaj	49	19	in	in	IN
cord-271501-yjobthaj	49	20	some	some	DT
cord-271501-yjobthaj	49	21	cells	cell	NNS
cord-271501-yjobthaj	49	22	?	?	.
cord-271501-yjobthaj	50	1	Will	Will	MD
cord-271501-yjobthaj	50	2	there	there	EX
cord-271501-yjobthaj	50	3	be	be	VB
cord-271501-yjobthaj	50	4	Golgi	Golgi	NNP
cord-271501-yjobthaj	50	5	apparatuses	apparatus	NNS
cord-271501-yjobthaj	50	6	in	in	IN
cord-271501-yjobthaj	50	7	which	which	WDT
cord-271501-yjobthaj	50	8	there	there	EX
cord-271501-yjobthaj	50	9	is	be	VBZ
cord-271501-yjobthaj	50	10	major	major	JJ
cord-271501-yjobthaj	50	11	overlapping	overlapping	NN
cord-271501-yjobthaj	50	12	of	of	IN
cord-271501-yjobthaj	50	13	these	these	DT
cord-271501-yjobthaj	50	14	different	different	JJ
cord-271501-yjobthaj	50	15	proteins	protein	NNS
cord-271501-yjobthaj	50	16	?	?	.
cord-271501-yjobthaj	51	1	In	in	IN
cord-271501-yjobthaj	51	2	the	the	DT
cord-271501-yjobthaj	51	3	case	case	NN
cord-271501-yjobthaj	51	4	of	of	IN
cord-271501-yjobthaj	51	5	the	the	DT
cord-271501-yjobthaj	51	6	yeast	yeast	NN
cord-271501-yjobthaj	51	7	Golgi	Golgi	NNP
cord-271501-yjobthaj	51	8	apparatus	apparatus	NN
cord-271501-yjobthaj	51	9	,	,	,
cord-271501-yjobthaj	51	10	the	the	DT
cord-271501-yjobthaj	51	11	possibility	possibility	NN
cord-271501-yjobthaj	51	12	exists	exist	VBZ
cord-271501-yjobthaj	51	13	that	that	IN
cord-271501-yjobthaj	51	14	these	these	DT
cord-271501-yjobthaj	51	15	transporters	transporter	NNS
cord-271501-yjobthaj	51	16	are	be	VBP
cord-271501-yjobthaj	51	17	not	not	RB
cord-271501-yjobthaj	51	18	polarized	polarize	VBN
cord-271501-yjobthaj	51	19	because	because	IN
cord-271501-yjobthaj	51	20	in	in	IN
cord-271501-yjobthaj	51	21	many	many	JJ
cord-271501-yjobthaj	51	22	instances	instance	NNS
cord-271501-yjobthaj	51	23	,	,	,
cord-271501-yjobthaj	51	24	this	this	DT
cord-271501-yjobthaj	51	25	organelle	organelle	NN
cord-271501-yjobthaj	51	26	consists	consist	VBZ
cord-271501-yjobthaj	51	27	of	of	IN
cord-271501-yjobthaj	51	28	only	only	RB
cord-271501-yjobthaj	51	29	one	one	CD
cord-271501-yjobthaj	51	30	cisternae	cisternae	NN
cord-271501-yjobthaj	51	31	(	(	-LRB-
cord-271501-yjobthaj	51	32	Preuss	Preuss	NNP
cord-271501-yjobthaj	51	33	et	et	FW
cord-271501-yjobthaj	51	34	al	al	NNP
cord-271501-yjobthaj	51	35	.	.	NNP
cord-271501-yjobthaj	51	36	,	,	,
cord-271501-yjobthaj	51	37	1992	1992	CD
cord-271501-yjobthaj	51	38	)	)	-RRB-
cord-271501-yjobthaj	51	39	.	.	.
cord-271501-yjobthaj	52	1	Nevertheless	nevertheless	RB
cord-271501-yjobthaj	52	2	,	,	,
cord-271501-yjobthaj	52	3	different	different	JJ
cord-271501-yjobthaj	52	4	cisternae	cisternae	NNP
cord-271501-yjobthaj	52	5	may	may	MD
cord-271501-yjobthaj	52	6	be	be	VB
cord-271501-yjobthaj	52	7	enriched	enrich	VBN
cord-271501-yjobthaj	52	8	in	in	IN
cord-271501-yjobthaj	52	9	individual	individual	JJ
cord-271501-yjobthaj	52	10	transporters	transporter	NNS
cord-271501-yjobthaj	52	11	.	.	.
cord-271501-yjobthaj	53	1	Clearly	clearly	RB
cord-271501-yjobthaj	53	2	,	,	,
cord-271501-yjobthaj	53	3	all	all	DT
cord-271501-yjobthaj	53	4	transporters	transporter	NNS
cord-271501-yjobthaj	53	5	could	could	MD
cord-271501-yjobthaj	53	6	colocalize	colocalize	VB
cord-271501-yjobthaj	53	7	and	and	CC
cord-271501-yjobthaj	53	8	still	still	RB
cord-271501-yjobthaj	53	9	allow	allow	VB
cord-271501-yjobthaj	53	10	oligosaccharide	oligosaccharide	NN
cord-271501-yjobthaj	53	11	chain	chain	NN
cord-271501-yjobthaj	53	12	specificity	specificity	NN
cord-271501-yjobthaj	53	13	to	to	TO
cord-271501-yjobthaj	53	14	proceed	proceed	VB
cord-271501-yjobthaj	53	15	normally	normally	RB
cord-271501-yjobthaj	53	16	as	as	IN
cord-271501-yjobthaj	53	17	a	a	DT
cord-271501-yjobthaj	53	18	result	result	NN
cord-271501-yjobthaj	53	19	of	of	IN
cord-271501-yjobthaj	53	20	substrate	substrate	JJ
cord-271501-yjobthaj	53	21	specificities	specificity	NNS
cord-271501-yjobthaj	53	22	of	of	IN
cord-271501-yjobthaj	53	23	glycosyltransferases	glycosyltransferase	NNS
cord-271501-yjobthaj	53	24	.	.	.
cord-271501-yjobthaj	54	1	Within	within	IN
cord-271501-yjobthaj	54	2	the	the	DT
cord-271501-yjobthaj	54	3	Golgi	Golgi	NNP
cord-271501-yjobthaj	54	4	membrane	membrane	NN
cord-271501-yjobthaj	54	5	,	,	,
cord-271501-yjobthaj	54	6	do	do	VB
cord-271501-yjobthaj	54	7	the	the	DT
cord-271501-yjobthaj	54	8	transporters	transporter	NNS
cord-271501-yjobthaj	54	9	and	and	CC
cord-271501-yjobthaj	54	10	the	the	DT
cord-271501-yjobthaj	54	11	transferases	transferase	NNS
cord-271501-yjobthaj	54	12	exist	exist	VBP
cord-271501-yjobthaj	54	13	as	as	IN
cord-271501-yjobthaj	54	14	structural	structural	JJ
cord-271501-yjobthaj	54	15	or	or	CC
cord-271501-yjobthaj	54	16	functional	functional	JJ
cord-271501-yjobthaj	54	17	complexes	complex	NNS
cord-271501-yjobthaj	54	18	?	?	.
cord-271501-yjobthaj	55	1	Radiation	radiation	NN
cord-271501-yjobthaj	55	2	inactivation	inactivation	NN
cord-271501-yjobthaj	55	3	studies	study	NNS
cord-271501-yjobthaj	55	4	suggest	suggest	VBP
cord-271501-yjobthaj	55	5	that	that	IN
cord-271501-yjobthaj	55	6	the	the	DT
cord-271501-yjobthaj	55	7	PAPS	PAPS	NNPS
cord-271501-yjobthaj	55	8	transporter	transporter	NN
cord-271501-yjobthaj	55	9	is	be	VBZ
cord-271501-yjobthaj	55	10	not	not	RB
cord-271501-yjobthaj	55	11	in	in	IN
cord-271501-yjobthaj	55	12	a	a	DT
cord-271501-yjobthaj	55	13	functional	functional	JJ
cord-271501-yjobthaj	55	14	complex	complex	NN
cord-271501-yjobthaj	55	15	with	with	IN
cord-271501-yjobthaj	55	16	any	any	DT
cord-271501-yjobthaj	55	17	corresponding	correspond	VBG
cord-271501-yjobthaj	55	18	sulfotransferases	sulfotransferase	NNS
cord-271501-yjobthaj	55	19	(	(	-LRB-
cord-271501-yjobthaj	55	20	Mandon	Mandon	NNP
cord-271501-yjobthaj	55	21	et	et	NNP
cord-271501-yjobthaj	55	22	al	al	NNP
cord-271501-yjobthaj	55	23	.	.	NNP
cord-271501-yjobthaj	55	24	,	,	,
cord-271501-yjobthaj	55	25	1994a	1994a	CD
cord-271501-yjobthaj	55	26	,	,	,
cord-271501-yjobthaj	55	27	b	b	LS
cord-271501-yjobthaj	55	28	)	)	-RRB-
cord-271501-yjobthaj	55	29	and	and	CC
cord-271501-yjobthaj	55	30	that	that	DT
cord-271501-yjobthaj	55	31	galactosyl	galactosyl	NNP
cord-271501-yjobthaj	55	32	and	and	CC
cord-271501-yjobthaj	55	33	sialyltransferases	sialyltransferase	NNS
cord-271501-yjobthaj	55	34	are	be	VBP
cord-271501-yjobthaj	55	35	not	not	RB
cord-271501-yjobthaj	55	36	in	in	IN
cord-271501-yjobthaj	55	37	a	a	DT
cord-271501-yjobthaj	55	38	functional	functional	JJ
cord-271501-yjobthaj	55	39	complex	complex	NN
cord-271501-yjobthaj	55	40	with	with	IN
cord-271501-yjobthaj	55	41	the	the	DT
cord-271501-yjobthaj	55	42	transporters	transporter	NNS
cord-271501-yjobthaj	55	43	(	(	-LRB-
cord-271501-yjobthaj	55	44	Fleischer	Fleischer	NNP
cord-271501-yjobthaj	55	45	et	et	NNP
cord-271501-yjobthaj	55	46	al	al	NNP
cord-271501-yjobthaj	55	47	.	.	NNP
cord-271501-yjobthaj	55	48	,	,	,
cord-271501-yjobthaj	55	49	1993	1993	CD
cord-271501-yjobthaj	55	50	)	)	-RRB-
cord-271501-yjobthaj	55	51	.	.	.
cord-271501-yjobthaj	56	1	Is	be	VBZ
cord-271501-yjobthaj	56	2	this	this	DT
cord-271501-yjobthaj	56	3	a	a	DT
cord-271501-yjobthaj	56	4	general	general	JJ
cord-271501-yjobthaj	56	5	observation	observation	NN
cord-271501-yjobthaj	56	6	?	?	.
cord-271501-yjobthaj	57	1	Undoubtedly	undoubtedly	RB
cord-271501-yjobthaj	57	2	,	,	,
cord-271501-yjobthaj	57	3	studies	study	NNS
cord-271501-yjobthaj	57	4	will	will	MD
cord-271501-yjobthaj	57	5	address	address	VB
cord-271501-yjobthaj	57	6	the	the	DT
cord-271501-yjobthaj	57	7	Golgi	Golgi	NNP
cord-271501-yjobthaj	57	8	targeting	targeting	NN
cord-271501-yjobthaj	57	9	features	feature	NNS
cord-271501-yjobthaj	57	10	of	of	IN
cord-271501-yjobthaj	57	11	these	these	DT
cord-271501-yjobthaj	57	12	transporters	transporter	NNS
cord-271501-yjobthaj	57	13	.	.	.
cord-271501-yjobthaj	58	1	These	these	DT
cord-271501-yjobthaj	58	2	approaches	approach	NNS
cord-271501-yjobthaj	58	3	will	will	MD
cord-271501-yjobthaj	58	4	consist	consist	VB
cord-271501-yjobthaj	58	5	of	of	IN
cord-271501-yjobthaj	58	6	either	either	DT
cord-271501-yjobthaj	58	7	mutagenizing	mutagenize	VBG
cord-271501-yjobthaj	58	8	different	different	JJ
cord-271501-yjobthaj	58	9	amino	amino	NN
cord-271501-yjobthaj	58	10	acids	acid	NNS
cord-271501-yjobthaj	58	11	of	of	IN
cord-271501-yjobthaj	58	12	the	the	DT
cord-271501-yjobthaj	58	13	transmembrane	transmembrane	NN
cord-271501-yjobthaj	58	14	and	and	CC
cord-271501-yjobthaj	58	15	adjacent	adjacent	JJ
cord-271501-yjobthaj	58	16	regions	region	NNS
cord-271501-yjobthaj	58	17	of	of	IN
cord-271501-yjobthaj	58	18	these	these	DT
cord-271501-yjobthaj	58	19	proteins	protein	NNS
cord-271501-yjobthaj	58	20	or	or	CC
cord-271501-yjobthaj	58	21	attaching	attach	VBG
cord-271501-yjobthaj	58	22	such	such	JJ
cord-271501-yjobthaj	58	23	regions	region	NNS
cord-271501-yjobthaj	58	24	to	to	IN
cord-271501-yjobthaj	58	25	plasma	plasma	NN
cord-271501-yjobthaj	58	26	membrane	membrane	NN
cord-271501-yjobthaj	58	27	proteins	protein	NNS
cord-271501-yjobthaj	58	28	and	and	CC
cord-271501-yjobthaj	58	29	studying	study	VBG
cord-271501-yjobthaj	58	30	their	-PRON-	PRP$
cord-271501-yjobthaj	58	31	subcellular	subcellular	JJ
cord-271501-yjobthaj	58	32	localization	localization	NN
cord-271501-yjobthaj	58	33	(	(	-LRB-
cord-271501-yjobthaj	58	34	Machamer	Machamer	NNP
cord-271501-yjobthaj	58	35	,	,	,
cord-271501-yjobthaj	58	36	1993	1993	CD
cord-271501-yjobthaj	58	37	;	;	:
cord-271501-yjobthaj	58	38	Gleeson	Gleeson	NNP
cord-271501-yjobthaj	58	39	et	et	NNP
cord-271501-yjobthaj	58	40	al	al	NNP
cord-271501-yjobthaj	58	41	,	,	,
cord-271501-yjobthaj	58	42	1994	1994	CD
cord-271501-yjobthaj	58	43	;	;	:
cord-271501-yjobthaj	58	44	Colley	Colley	NNP
cord-271501-yjobthaj	58	45	,	,	,
cord-271501-yjobthaj	58	46	in	in	IN
cord-271501-yjobthaj	58	47	press	press	NN
cord-271501-yjobthaj	58	48	)	)	-RRB-
cord-271501-yjobthaj	58	49	.	.	.
cord-271501-yjobthaj	59	1	These	these	DT
cord-271501-yjobthaj	59	2	studies	study	NNS
cord-271501-yjobthaj	59	3	with	with	IN
cord-271501-yjobthaj	59	4	multitransmembrane	multitransmembrane	NNP
cord-271501-yjobthaj	59	5	proteins	protein	NNS
cord-271501-yjobthaj	59	6	of	of	IN
cord-271501-yjobthaj	59	7	the	the	DT
cord-271501-yjobthaj	59	8	Golgi	Golgi	NNP
cord-271501-yjobthaj	59	9	membrane	membrane	NN
cord-271501-yjobthaj	60	1	(	(	-LRB-
cord-271501-yjobthaj	60	2	Rudolph	Rudolph	NNP
cord-271501-yjobthaj	60	3	et	et	NNP
cord-271501-yjobthaj	60	4	al	al	NNP
cord-271501-yjobthaj	60	5	,	,	,
cord-271501-yjobthaj	60	6	1989	1989	CD
cord-271501-yjobthaj	60	7	;	;	:
cord-271501-yjobthaj	61	1	Swift	Swift	NNP
cord-271501-yjobthaj	61	2	and	and	CC
cord-271501-yjobthaj	61	3	Machamer	Machamer	NNP
cord-271501-yjobthaj	61	4	,	,	,
cord-271501-yjobthaj	61	5	1991	1991	CD
cord-271501-yjobthaj	61	6	;	;	:
cord-271501-yjobthaj	61	7	Antebi	Antebi	NNP
cord-271501-yjobthaj	61	8	and	and	CC
cord-271501-yjobthaj	61	9	Fink	Fink	NNP
cord-271501-yjobthaj	61	10	,	,	,
cord-271501-yjobthaj	61	11	1992	1992	CD
cord-271501-yjobthaj	61	12	)	)	-RRB-
cord-271501-yjobthaj	61	13	and	and	CC
cord-271501-yjobthaj	61	14	the	the	DT
cord-271501-yjobthaj	61	15	above	above	JJ
cord-271501-yjobthaj	61	16	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	61	17	sugar	sugar	NN
cord-271501-yjobthaj	61	18	transporters	transporter	NNS
cord-271501-yjobthaj	61	19	,	,	,
cord-271501-yjobthaj	61	20	by	by	IN
cord-271501-yjobthaj	61	21	analogy	analogy	NN
cord-271501-yjobthaj	61	22	to	to	IN
cord-271501-yjobthaj	61	23	glycosyltransferases	glycosyltransferases	NNP
cord-271501-yjobthaj	61	24	,	,	,
cord-271501-yjobthaj	61	25	may	may	MD
cord-271501-yjobthaj	61	26	not	not	RB
cord-271501-yjobthaj	61	27	always	always	RB
cord-271501-yjobthaj	61	28	yield	yield	VB
cord-271501-yjobthaj	61	29	interpretable	interpretable	JJ
cord-271501-yjobthaj	61	30	results	result	NNS
cord-271501-yjobthaj	61	31	.	.	.
cord-271501-yjobthaj	62	1	The	the	DT
cord-271501-yjobthaj	62	2	extent	extent	NN
cord-271501-yjobthaj	62	3	to	to	TO
cord-271501-yjobthaj	62	4	which	which	WDT
cord-271501-yjobthaj	62	5	constructs	construct	NNS
cord-271501-yjobthaj	62	6	expressed	express	VBN
cord-271501-yjobthaj	62	7	in	in	IN
cord-271501-yjobthaj	62	8	one	one	CD
cord-271501-yjobthaj	62	9	cell	cell	NN
cord-271501-yjobthaj	62	10	line	line	NN
cord-271501-yjobthaj	62	11	or	or	CC
cord-271501-yjobthaj	62	12	organism	organism	NN
cord-271501-yjobthaj	62	13	will	will	MD
cord-271501-yjobthaj	62	14	localize	localize	VB
cord-271501-yjobthaj	62	15	to	to	IN
cord-271501-yjobthaj	62	16	the	the	DT
cord-271501-yjobthaj	62	17	same	same	JJ
cord-271501-yjobthaj	62	18	organelle	organelle	NN
cord-271501-yjobthaj	62	19	in	in	IN
cord-271501-yjobthaj	62	20	another	another	DT
cord-271501-yjobthaj	62	21	cell	cell	NN
cord-271501-yjobthaj	62	22	line	line	NN
cord-271501-yjobthaj	62	23	or	or	CC
cord-271501-yjobthaj	62	24	organism	organism	NN
cord-271501-yjobthaj	62	25	must	must	MD
cord-271501-yjobthaj	62	26	be	be	VB
cord-271501-yjobthaj	62	27	determined	determine	VBN
cord-271501-yjobthaj	62	28	.	.	.
cord-271501-yjobthaj	63	1	Do	do	VBP
cord-271501-yjobthaj	63	2	transporters	transporter	NNS
cord-271501-yjobthaj	63	3	recycle	recycle	VB
cord-271501-yjobthaj	63	4	between	between	IN
cord-271501-yjobthaj	63	5	the	the	DT
cord-271501-yjobthaj	63	6	Golgi	Golgi	NNP
cord-271501-yjobthaj	63	7	and	and	CC
cord-271501-yjobthaj	63	8	the	the	DT
cord-271501-yjobthaj	63	9	ER	er	NN
cord-271501-yjobthaj	63	10	?	?	.
cord-271501-yjobthaj	64	1	Some	some	DT
cord-271501-yjobthaj	64	2	,	,	,
cord-271501-yjobthaj	64	3	as	as	IN
cord-271501-yjobthaj	64	4	in	in	IN
cord-271501-yjobthaj	64	5	S.cerevisiae	S.cerevisiae	NNS
cord-271501-yjobthaj	65	1	(	(	-LRB-
cord-271501-yjobthaj	65	2	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	65	3	et	et	NNP
cord-271501-yjobthaj	65	4	al	al	NNP
cord-271501-yjobthaj	65	5	.	.	NNP
cord-271501-yjobthaj	65	6	,	,	,
cord-271501-yjobthaj	65	7	1996	1996	CD
cord-271501-yjobthaj	65	8	)	)	-RRB-
cord-271501-yjobthaj	65	9	,	,	,
cord-271501-yjobthaj	65	10	have	have	VBP
cord-271501-yjobthaj	65	11	a	a	DT
cord-271501-yjobthaj	65	12	KKXX	KKXX	NNP
cord-271501-yjobthaj	65	13	signal	signal	NN
cord-271501-yjobthaj	65	14	(	(	-LRB-
cord-271501-yjobthaj	65	15	Jackson	Jackson	NNP
cord-271501-yjobthaj	65	16	et	et	NNP
cord-271501-yjobthaj	65	17	al	al	NNP
cord-271501-yjobthaj	65	18	.	.	NNP
cord-271501-yjobthaj	65	19	,	,	,
cord-271501-yjobthaj	65	20	1990	1990	CD
cord-271501-yjobthaj	65	21	;	;	:
cord-271501-yjobthaj	65	22	Townsley	Townsley	NNP
cord-271501-yjobthaj	65	23	and	and	CC
cord-271501-yjobthaj	65	24	Pelham	Pelham	NNP
cord-271501-yjobthaj	65	25	,	,	,
cord-271501-yjobthaj	65	26	1994	1994	CD
cord-271501-yjobthaj	65	27	;	;	:
cord-271501-yjobthaj	65	28	Schroeder	Schroeder	NNP
cord-271501-yjobthaj	65	29	et	et	NNP
cord-271501-yjobthaj	65	30	al	al	NNP
cord-271501-yjobthaj	65	31	,	,	,
cord-271501-yjobthaj	65	32	1995	1995	CD
cord-271501-yjobthaj	65	33	)	)	-RRB-
cord-271501-yjobthaj	65	34	,	,	,
cord-271501-yjobthaj	65	35	while	while	IN
cord-271501-yjobthaj	65	36	some	some	DT
cord-271501-yjobthaj	65	37	in	in	IN
cord-271501-yjobthaj	65	38	K.lactis	K.lactis	NNP
cord-271501-yjobthaj	65	39	(	(	-LRB-
cord-271501-yjobthaj	65	40	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	65	41	et	et	NNP
cord-271501-yjobthaj	65	42	al	al	NNP
cord-271501-yjobthaj	65	43	,	,	,
cord-271501-yjobthaj	65	44	1996	1996	CD
cord-271501-yjobthaj	65	45	)	)	-RRB-
cord-271501-yjobthaj	65	46	do	do	VBP
cord-271501-yjobthaj	65	47	not	not	RB
cord-271501-yjobthaj	65	48	.	.	.
cord-271501-yjobthaj	66	1	Is	be	VBZ
cord-271501-yjobthaj	66	2	this	this	DT
cord-271501-yjobthaj	66	3	of	of	IN
cord-271501-yjobthaj	66	4	relevance	relevance	NN
cord-271501-yjobthaj	66	5	?	?	.
cord-271501-yjobthaj	67	1	In	in	IN
cord-271501-yjobthaj	67	2	summary	summary	NN
cord-271501-yjobthaj	67	3	,	,	,
cord-271501-yjobthaj	67	4	although	although	IN
cord-271501-yjobthaj	67	5	much	much	JJ
cord-271501-yjobthaj	67	6	has	have	VBZ
cord-271501-yjobthaj	67	7	been	be	VBN
cord-271501-yjobthaj	67	8	learned	learn	VBN
cord-271501-yjobthaj	67	9	about	about	IN
cord-271501-yjobthaj	67	10	Golgi	Golgi	NNP
cord-271501-yjobthaj	67	11	transport	transport	NN
cord-271501-yjobthaj	67	12	of	of	IN
cord-271501-yjobthaj	67	13	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	67	14	sugars	sugar	NNS
cord-271501-yjobthaj	67	15	,	,	,
cord-271501-yjobthaj	67	16	PAPS	pap	NNS
cord-271501-yjobthaj	67	17	,	,	,
cord-271501-yjobthaj	67	18	and	and	CC
cord-271501-yjobthaj	67	19	ATP	ATP	NNP
cord-271501-yjobthaj	67	20	during	during	IN
cord-271501-yjobthaj	67	21	the	the	DT
cord-271501-yjobthaj	67	22	past	past	JJ
cord-271501-yjobthaj	67	23	years	year	NNS
cord-271501-yjobthaj	67	24	we	-PRON-	PRP
cord-271501-yjobthaj	67	25	are	be	VBP
cord-271501-yjobthaj	67	26	clearly	clearly	RB
cord-271501-yjobthaj	67	27	at	at	IN
cord-271501-yjobthaj	67	28	the	the	DT
cord-271501-yjobthaj	67	29	dawn	dawn	NN
cord-271501-yjobthaj	67	30	of	of	IN
cord-271501-yjobthaj	67	31	a	a	DT
cord-271501-yjobthaj	67	32	new	new	JJ
cord-271501-yjobthaj	67	33	era	era	NN
cord-271501-yjobthaj	67	34	.	.	.
cord-271501-yjobthaj	68	1	This	this	DT
cord-271501-yjobthaj	68	2	will	will	MD
cord-271501-yjobthaj	68	3	,	,	,
cord-271501-yjobthaj	68	4	hopefully	hopefully	RB
cord-271501-yjobthaj	68	5	,	,	,
cord-271501-yjobthaj	68	6	bring	bring	VB
cord-271501-yjobthaj	68	7	more	more	JJR
cord-271501-yjobthaj	68	8	investigators	investigator	NNS
cord-271501-yjobthaj	68	9	into	into	IN
cord-271501-yjobthaj	68	10	this	this	DT
cord-271501-yjobthaj	68	11	field	field	NN
cord-271501-yjobthaj	68	12	and	and	CC
cord-271501-yjobthaj	68	13	thereby	thereby	RB
cord-271501-yjobthaj	68	14	allow	allow	VB
cord-271501-yjobthaj	68	15	a	a	DT
cord-271501-yjobthaj	68	16	faster	fast	JJR
cord-271501-yjobthaj	68	17	pace	pace	NN
cord-271501-yjobthaj	68	18	in	in	IN
cord-271501-yjobthaj	68	19	obtaining	obtain	VBG
cord-271501-yjobthaj	68	20	answers	answer	NNS
cord-271501-yjobthaj	68	21	to	to	IN
cord-271501-yjobthaj	68	22	the	the	DT
cord-271501-yjobthaj	68	23	above	above	JJ
cord-271501-yjobthaj	68	24	important	important	JJ
cord-271501-yjobthaj	68	25	questions	question	NNS
cord-271501-yjobthaj	68	26	.	.	.
cord-271501-yjobthaj	69	1	Topography	topography	NN
cord-271501-yjobthaj	69	2	of	of	IN
cord-271501-yjobthaj	69	3	glycosylation	glycosylation	NN
cord-271501-yjobthaj	69	4	in	in	IN
cord-271501-yjobthaj	69	5	yeast	yeast	NN
cord-271501-yjobthaj	69	6	.	.	.
cord-271501-yjobthaj	70	1	Characterization	characterization	NN
cord-271501-yjobthaj	70	2	of	of	IN
cord-271501-yjobthaj	70	3	GDP	gdp	NN
cord-271501-yjobthaj	70	4	-	-	HYPH
cord-271501-yjobthaj	70	5	mannose	mannose	NN
cord-271501-yjobthaj	70	6	transport	transport	NN
cord-271501-yjobthaj	70	7	and	and	CC
cord-271501-yjobthaj	70	8	lumenal	lumenal	JJ
cord-271501-yjobthaj	70	9	guanosine	guanosine	NN
cord-271501-yjobthaj	70	10	diphosphatase	diphosphatase	NN
cord-271501-yjobthaj	70	11	activities	activity	NNS
cord-271501-yjobthaj	70	12	in	in	IN
cord-271501-yjobthaj	70	13	Golgi	Golgi	NNP
cord-271501-yjobthaj	70	14	-	-	HYPH
cord-271501-yjobthaj	70	15	like	like	JJ
cord-271501-yjobthaj	70	16	vesicles	vesicle	NNS
cord-271501-yjobthaj	70	17	Guanosine	Guanosine	NNP
cord-271501-yjobthaj	70	18	diphosphatase	diphosphatase	NN
cord-271501-yjobthaj	70	19	is	be	VBZ
cord-271501-yjobthaj	70	20	required	require	VBN
cord-271501-yjobthaj	70	21	for	for	IN
cord-271501-yjobthaj	70	22	protein	protein	NN
cord-271501-yjobthaj	70	23	and	and	CC
cord-271501-yjobthaj	70	24	sphingolipid	sphingolipid	NN
cord-271501-yjobthaj	70	25	glycosylation	glycosylation	NN
cord-271501-yjobthaj	70	26	in	in	IN
cord-271501-yjobthaj	70	27	the	the	DT
cord-271501-yjobthaj	70	28	Golgi	Golgi	NNP
cord-271501-yjobthaj	70	29	lumen	lumen	NN
cord-271501-yjobthaj	70	30	of	of	IN
cord-271501-yjobthaj	70	31	Saccharomyces	saccharomyce	NNS
cord-271501-yjobthaj	70	32	cerevisiae	cerevisiae	VBZ
cord-271501-yjobthaj	70	33	A	a	DT
cord-271501-yjobthaj	70	34	mutant	mutant	JJ
cord-271501-yjobthaj	70	35	yeasl	yeasl	NN
cord-271501-yjobthaj	70	36	deficient	deficient	JJ
cord-271501-yjobthaj	70	37	in	in	IN
cord-271501-yjobthaj	70	38	Golgi	Golgi	NNP
cord-271501-yjobthaj	70	39	transport	transport	NN
cord-271501-yjobthaj	70	40	of	of	IN
cord-271501-yjobthaj	70	41	uridine	uridine	NN
cord-271501-yjobthaj	70	42	diphosphate	diphosphate	NNP
cord-271501-yjobthaj	70	43	N	N	NNP
cord-271501-yjobthaj	70	44	-	-	HYPH
cord-271501-yjobthaj	70	45	acetylglucosamine	acetylglucosamine	NNP
cord-271501-yjobthaj	70	46	Molecular	Molecular	NNP
cord-271501-yjobthaj	70	47	cloning	cloning	NN
cord-271501-yjobthaj	70	48	of	of	IN
cord-271501-yjobthaj	70	49	the	the	DT
cord-271501-yjobthaj	70	50	Golgi	Golgi	NNP
cord-271501-yjobthaj	70	51	apparatus	apparatus	NN
cord-271501-yjobthaj	70	52	uridine	uridine	NN
cord-271501-yjobthaj	70	53	diphosphate	diphosphate	NN
cord-271501-yjobthaj	70	54	-	-	HYPH
cord-271501-yjobthaj	70	55	N	N	NNP
cord-271501-yjobthaj	70	56	-	-	HYPH
cord-271501-yjobthaj	70	57	acetylglucosamine	acetylglucosamine	NN
cord-271501-yjobthaj	70	58	transporter	transporter	NN
cord-271501-yjobthaj	70	59	from	from	IN
cord-271501-yjobthaj	70	60	Kluyveromyces	Kluyveromyces	NNP
cord-271501-yjobthaj	70	61	Laclis	Laclis	NNP
cord-271501-yjobthaj	71	1	The	the	DT
cord-271501-yjobthaj	71	2	yeast	yeast	NN
cord-271501-yjobthaj	72	1	Ca	ca	NN
cord-271501-yjobthaj	72	2	2	2	CD
cord-271501-yjobthaj	72	3	*	*	NFP
cord-271501-yjobthaj	72	4	-ATPase	-atpase	NN
cord-271501-yjobthaj	72	5	homologue	homologue	NN
cord-271501-yjobthaj	72	6	,	,	,
cord-271501-yjobthaj	72	7	PMR1	PMR1	NNP
cord-271501-yjobthaj	72	8	,	,	,
cord-271501-yjobthaj	72	9	is	be	VBZ
cord-271501-yjobthaj	72	10	required	require	VBN
cord-271501-yjobthaj	72	11	for	for	IN
cord-271501-yjobthaj	72	12	normal	normal	JJ
cord-271501-yjobthaj	72	13	Golgi	Golgi	NNP
cord-271501-yjobthaj	72	14	function	function	NN
cord-271501-yjobthaj	72	15	and	and	CC
cord-271501-yjobthaj	72	16	localizes	localize	VBZ
cord-271501-yjobthaj	72	17	in	in	IN
cord-271501-yjobthaj	72	18	novel	novel	JJ
cord-271501-yjobthaj	72	19	Golgi	Golgi	NNP
cord-271501-yjobthaj	72	20	-	-	HYPH
cord-271501-yjobthaj	72	21	like	like	JJ
cord-271501-yjobthaj	72	22	distribution	distribution	NN
cord-271501-yjobthaj	72	23	Purification	purification	NN
cord-271501-yjobthaj	72	24	and	and	CC
cord-271501-yjobthaj	72	25	functional	functional	JJ
cord-271501-yjobthaj	72	26	reconstirution	reconstirution	NN
cord-271501-yjobthaj	72	27	of	of	IN
cord-271501-yjobthaj	72	28	the	the	DT
cord-271501-yjobthaj	72	29	cystic	cystic	JJ
cord-271501-yjobthaj	72	30	fibrosis	fibrosis	NN
cord-271501-yjobthaj	72	31	transmembrane	transmembrane	NNP
cord-271501-yjobthaj	72	32	conductance	conductance	NN
cord-271501-yjobthaj	72	33	regulator	regulator	NN
cord-271501-yjobthaj	72	34	(	(	-LRB-
cord-271501-yjobthaj	72	35	CFTR	CFTR	NNP
cord-271501-yjobthaj	72	36	)	)	-RRB-
cord-271501-yjobthaj	73	1	The	the	DT
cord-271501-yjobthaj	73	2	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	3	guanosine	guanosine	NN
cord-271501-yjobthaj	73	4	diphosphatase	diphosphatase	NN
cord-271501-yjobthaj	73	5	is	be	VBZ
cord-271501-yjobthaj	73	6	required	require	VBN
cord-271501-yjobthaj	73	7	for	for	IN
cord-271501-yjobthaj	73	8	transport	transport	NN
cord-271501-yjobthaj	73	9	of	of	IN
cord-271501-yjobthaj	73	10	GDP	gdp	NN
cord-271501-yjobthaj	73	11	-	-	HYPH
cord-271501-yjobthaj	73	12	mannose	mannose	NN
cord-271501-yjobthaj	73	13	into	into	IN
cord-271501-yjobthaj	73	14	the	the	DT
cord-271501-yjobthaj	73	15	lumen	lumen	NN
cord-271501-yjobthaj	73	16	of	of	IN
cord-271501-yjobthaj	73	17	Saccharomyces	saccharomyce	NNS
cord-271501-yjobthaj	73	18	cerevisiae	cerevisiae	VBZ
cord-271501-yjobthaj	73	19	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	20	vesicles	vesicle	NNS
cord-271501-yjobthaj	73	21	Effect	effect	NN
cord-271501-yjobthaj	73	22	of	of	IN
cord-271501-yjobthaj	73	23	nuclcotides	nuclcotide	NNS
cord-271501-yjobthaj	73	24	on	on	IN
cord-271501-yjobthaj	73	25	translocation	translocation	NN
cord-271501-yjobthaj	73	26	of	of	IN
cord-271501-yjobthaj	73	27	sugar	sugar	NN
cord-271501-yjobthaj	73	28	nucleotides	nucleotide	NNS
cord-271501-yjobthaj	73	29	and	and	CC
cord-271501-yjobthaj	73	30	adenosine	adenosine	NN
cord-271501-yjobthaj	73	31	3	3	CD
cord-271501-yjobthaj	73	32	'	'	''
cord-271501-yjobthaj	73	33	phosphate	phosphate	NN
cord-271501-yjobthaj	73	34	5	5	CD
cord-271501-yjobthaj	73	35	'	'	''
cord-271501-yjobthaj	73	36	phosphosulfate	phosphosulfate	NN
cord-271501-yjobthaj	73	37	into	into	IN
cord-271501-yjobthaj	73	38	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	39	apparatus	apparatus	NN
cord-271501-yjobthaj	73	40	vesicles	vesicle	NNS
cord-271501-yjobthaj	73	41	Mechanism	mechanism	NN
cord-271501-yjobthaj	73	42	of	of	IN
cord-271501-yjobthaj	73	43	phosphorylation	phosphorylation	NN
cord-271501-yjobthaj	73	44	in	in	IN
cord-271501-yjobthaj	73	45	the	the	DT
cord-271501-yjobthaj	73	46	lumen	lumen	NN
cord-271501-yjobthaj	73	47	of	of	IN
cord-271501-yjobthaj	73	48	the	the	DT
cord-271501-yjobthaj	73	49	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	50	apparatus	apparatus	NN
cord-271501-yjobthaj	73	51	:	:	:
cord-271501-yjobthaj	73	52	translocation	translocation	NN
cord-271501-yjobthaj	73	53	of	of	IN
cord-271501-yjobthaj	73	54	adenosine	adenosine	NN
cord-271501-yjobthaj	73	55	5	5	CD
cord-271501-yjobthaj	73	56	'	'	''
cord-271501-yjobthaj	73	57	triphosphate	triphosphate	NN
cord-271501-yjobthaj	73	58	into	into	IN
cord-271501-yjobthaj	73	59	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	60	vesicles	vesicle	NNS
cord-271501-yjobthaj	73	61	for	for	IN
cord-271501-yjobthaj	73	62	rat	rat	NN
cord-271501-yjobthaj	73	63	liver	liver	NN
cord-271501-yjobthaj	73	64	and	and	CC
cord-271501-yjobthaj	73	65	mammary	mammary	JJ
cord-271501-yjobthaj	73	66	gland	gland	NN
cord-271501-yjobthaj	73	67	Translocation	Translocation	NNP
cord-271501-yjobthaj	73	68	of	of	IN
cord-271501-yjobthaj	73	69	ATP	ATP	NNP
cord-271501-yjobthaj	73	70	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	71	membrane	membrane	NN
cord-271501-yjobthaj	73	72	transporters	transporter	NNS
cord-271501-yjobthaj	73	73	into	into	IN
cord-271501-yjobthaj	73	74	the	the	DT
cord-271501-yjobthaj	73	75	lumen	lumen	NN
cord-271501-yjobthaj	73	76	of	of	IN
cord-271501-yjobthaj	73	77	the	the	DT
cord-271501-yjobthaj	73	78	rough	rough	JJ
cord-271501-yjobthaj	73	79	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	73	80	rcticulum	rcticulum	NN
cord-271501-yjobthaj	73	81	-	-	HYPH
cord-271501-yjobthaj	73	82	derived	derive	VBN
cord-271501-yjobthaj	73	83	vesicles	vesicle	NNS
cord-271501-yjobthaj	73	84	and	and	CC
cord-271501-yjobthaj	73	85	its	-PRON-	PRP$
cord-271501-yjobthaj	73	86	binding	binding	NN
cord-271501-yjobthaj	73	87	to	to	IN
cord-271501-yjobthaj	73	88	lumenal	lumenal	JJ
cord-271501-yjobthaj	73	89	proteins	protein	NNS
cord-271501-yjobthaj	73	90	including	include	VBG
cord-271501-yjobthaj	73	91	BiP	BiP	NNP
cord-271501-yjobthaj	73	92	(	(	-LRB-
cord-271501-yjobthaj	73	93	GRP	GRP	NNP
cord-271501-yjobthaj	73	94	78	78	CD
cord-271501-yjobthaj	73	95	)	)	-RRB-
cord-271501-yjobthaj	73	96	and	and	CC
cord-271501-yjobthaj	73	97	GRP	GRP	NNP
cord-271501-yjobthaj	73	98	94	94	CD
cord-271501-yjobthaj	73	99	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	100	localization	localization	NN
cord-271501-yjobthaj	73	101	of	of	IN
cord-271501-yjobthaj	73	102	glycosyltransferases	glycosyltransferase	NNS
cord-271501-yjobthaj	73	103	:	:	:
cord-271501-yjobthaj	73	104	more	more	JJR
cord-271501-yjobthaj	73	105	questions	question	NNS
cord-271501-yjobthaj	73	106	than	than	IN
cord-271501-yjobthaj	73	107	answers	answer	NNS
cord-271501-yjobthaj	73	108	Expression	expression	NN
cord-271501-yjobthaj	73	109	cloning	cloning	NN
cord-271501-yjobthaj	73	110	of	of	IN
cord-271501-yjobthaj	73	111	the	the	DT
cord-271501-yjobthaj	73	112	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	113	CMP	CMP	NNP
cord-271501-yjobthaj	73	114	sialic	sialic	NN
cord-271501-yjobthaj	73	115	acid	acid	NN
cord-271501-yjobthaj	73	116	transporter	transporter	NN
cord-271501-yjobthaj	73	117	Target	Target	NNP
cord-271501-yjobthaj	73	118	sizes	size	NNS
cord-271501-yjobthaj	73	119	of	of	IN
cord-271501-yjobthaj	73	120	galactosyltransferase	galactosyltransferase	NNP
cord-271501-yjobthaj	73	121	,	,	,
cord-271501-yjobthaj	73	122	sialyltransferase	sialyltransferase	NNP
cord-271501-yjobthaj	73	123	and	and	CC
cord-271501-yjobthaj	73	124	uridinediphosphatase	uridinediphosphatase	NN
cord-271501-yjobthaj	73	125	in	in	IN
cord-271501-yjobthaj	73	126	the	the	DT
cord-271501-yjobthaj	73	127	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	128	apparatus	apparatus	NN
cord-271501-yjobthaj	73	129	of	of	IN
cord-271501-yjobthaj	73	130	rat	rat	NN
cord-271501-yjobthaj	73	131	bver	bver	IN
cord-271501-yjobthaj	73	132	Cystine	Cystine	NNP
cord-271501-yjobthaj	73	133	transport	transport	NN
cord-271501-yjobthaj	73	134	is	be	VBZ
cord-271501-yjobthaj	73	135	defective	defective	JJ
cord-271501-yjobthaj	73	136	in	in	IN
cord-271501-yjobthaj	73	137	isolated	isolate	VBN
cord-271501-yjobthaj	73	138	leukocyte	leukocyte	NN
cord-271501-yjobthaj	73	139	lysosomes	lysosome	NNS
cord-271501-yjobthaj	73	140	from	from	IN
cord-271501-yjobthaj	73	141	patients	patient	NNS
cord-271501-yjobthaj	73	142	with	with	IN
cord-271501-yjobthaj	73	143	cystinosis	cystinosis	NN
cord-271501-yjobthaj	73	144	Targeting	targeting	NN
cord-271501-yjobthaj	73	145	of	of	IN
cord-271501-yjobthaj	73	146	proteins	protein	NNS
cord-271501-yjobthaj	73	147	to	to	IN
cord-271501-yjobthaj	73	148	the	the	DT
cord-271501-yjobthaj	73	149	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	150	apparatus	apparatus	NN
cord-271501-yjobthaj	73	151	Topography	Topography	NNP
cord-271501-yjobthaj	73	152	of	of	IN
cord-271501-yjobthaj	73	153	glycosylanon	glycosylanon	NN
cord-271501-yjobthaj	73	154	in	in	IN
cord-271501-yjobthaj	73	155	the	the	DT
cord-271501-yjobthaj	73	156	rough	rough	JJ
cord-271501-yjobthaj	73	157	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	73	158	reticulum	reticulum	NN
cord-271501-yjobthaj	73	159	and	and	CC
cord-271501-yjobthaj	73	160	Golgi	Golgi	NNP
cord-271501-yjobthaj	73	161	apparatus	apparatus	NN
cord-271501-yjobthaj	73	162	Mice	mouse	NNS
cord-271501-yjobthaj	73	163	lacking	lack	VBG
cord-271501-yjobthaj	74	1	N	N	NNP
cord-271501-yjobthaj	74	2	-	-	NN
cord-271501-yjobthaj	74	3	acetylglucosaminyltransferase	acetylglucosaminyltransferase	NNP
cord-271501-yjobthaj	75	1	I	-PRON-	PRP
cord-271501-yjobthaj	75	2	activity	activity	NN
cord-271501-yjobthaj	75	3	die	die	VBP
cord-271501-yjobthaj	75	4	at	at	IN
cord-271501-yjobthaj	75	5	mid	mid	NN
cord-271501-yjobthaj	75	6	-	-	NN
cord-271501-yjobthaj	75	7	gestation	gestation	NN
cord-271501-yjobthaj	75	8	revealing	reveal	VBG
cord-271501-yjobthaj	75	9	an	an	DT
cord-271501-yjobthaj	75	10	essential	essential	JJ
cord-271501-yjobthaj	75	11	role	role	NN
cord-271501-yjobthaj	75	12	for	for	IN
cord-271501-yjobthaj	75	13	complex	complex	JJ
cord-271501-yjobthaj	75	14	or	or	CC
cord-271501-yjobthaj	75	15	hybrid	hybrid	JJ
cord-271501-yjobthaj	75	16	N	n	CD
cord-271501-yjobthaj	75	17	-	-	HYPH
cord-271501-yjobthaj	75	18	lmked	lmked	JJ
cord-271501-yjobthaj	75	19	carbohydrates	carbohydrate	NNS
cord-271501-yjobthaj	75	20	Identification	Identification	NNP
cord-271501-yjobthaj	75	21	of	of	IN
cord-271501-yjobthaj	75	22	a	a	DT
cord-271501-yjobthaj	75	23	consensus	consensus	NN
cord-271501-yjobthaj	75	24	motif	motif	NN
cord-271501-yjobthaj	75	25	for	for	IN
cord-271501-yjobthaj	75	26	retention	retention	NN
cord-271501-yjobthaj	75	27	of	of	IN
cord-271501-yjobthaj	75	28	transmembrane	transmembrane	JJ
cord-271501-yjobthaj	75	29	proteins	protein	NNS
cord-271501-yjobthaj	75	30	in	in	IN
cord-271501-yjobthaj	75	31	the	the	DT
cord-271501-yjobthaj	75	32	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	75	33	reuculum	reuculum	NN
cord-271501-yjobthaj	75	34	Dialectics	Dialectics	NNP
cord-271501-yjobthaj	75	35	in	in	IN
cord-271501-yjobthaj	75	36	carrier	carrier	NN
cord-271501-yjobthaj	75	37	research	research	NN
cord-271501-yjobthaj	75	38	:	:	:
cord-271501-yjobthaj	75	39	the	the	DT
cord-271501-yjobthaj	75	40	ADP	ADP	NNP
cord-271501-yjobthaj	75	41	/	/	SYM
cord-271501-yjobthaj	75	42	ATP	ATP	NNP
cord-271501-yjobthaj	75	43	carrier	carrier	NN
cord-271501-yjobthaj	75	44	and	and	CC
cord-271501-yjobthaj	75	45	the	the	DT
cord-271501-yjobthaj	75	46	uncoupling	uncoupling	JJ
cord-271501-yjobthaj	75	47	protein	protein	NN
cord-271501-yjobthaj	75	48	Golgi	Golgi	NNP
cord-271501-yjobthaj	75	49	GDPmannose	GDPmannose	NNP
cord-271501-yjobthaj	75	50	requires	require	VBZ
cord-271501-yjobthaj	75	51	Leishmania	Leishmania	NNP
cord-271501-yjobthaj	75	52	LPG2	LPG2	NNP
cord-271501-yjobthaj	75	53	:	:	:
cord-271501-yjobthaj	75	54	a	a	DT
cord-271501-yjobthaj	75	55	member	member	NN
cord-271501-yjobthaj	75	56	of	of	IN
cord-271501-yjobthaj	75	57	a	a	DT
cord-271501-yjobthaj	75	58	eukaryotic	eukaryotic	JJ
cord-271501-yjobthaj	75	59	family	family	NN
cord-271501-yjobthaj	75	60	of	of	IN
cord-271501-yjobthaj	75	61	putative	putative	JJ
cord-271501-yjobthaj	75	62	nucleotide	nucleotide	JJ
cord-271501-yjobthaj	75	63	-	-	HYPH
cord-271501-yjobthaj	75	64	sugar	sugar	NN
cord-271501-yjobthaj	75	65	transporter	transporter	NN
cord-271501-yjobthaj	75	66	Targeting	targeting	NN
cord-271501-yjobthaj	75	67	and	and	CC
cord-271501-yjobthaj	75	68	retention	retention	NN
cord-271501-yjobthaj	75	69	of	of	IN
cord-271501-yjobthaj	75	70	Golgi	Golgi	NNP
cord-271501-yjobthaj	75	71	membrane	membrane	NN
cord-271501-yjobthaj	75	72	proteins	protein	NNS
cord-271501-yjobthaj	75	73	Characterization	characterization	NN
cord-271501-yjobthaj	75	74	of	of	IN
cord-271501-yjobthaj	75	75	a	a	DT
cord-271501-yjobthaj	75	76	proton	proton	NN
cord-271501-yjobthaj	75	77	-	-	HYPH
cord-271501-yjobthaj	75	78	driven	drive	VBN
cord-271501-yjobthaj	75	79	carrier	carrier	NN
cord-271501-yjobthaj	75	80	for	for	IN
cord-271501-yjobthaj	75	81	sialic	sialic	JJ
cord-271501-yjobthaj	75	82	acid	acid	NN
cord-271501-yjobthaj	75	83	in	in	IN
cord-271501-yjobthaj	75	84	the	the	DT
cord-271501-yjobthaj	75	85	lysosomal	lysosomal	JJ
cord-271501-yjobthaj	75	86	membrane	membrane	NN
cord-271501-yjobthaj	75	87	Purification	purification	NN
cord-271501-yjobthaj	75	88	of	of	IN
cord-271501-yjobthaj	75	89	tbe	tbe	NNP
cord-271501-yjobthaj	75	90	Golgi	Golgi	NNP
cord-271501-yjobthaj	75	91	adenosine	adenosine	NN
cord-271501-yjobthaj	75	92	3	3	CD
cord-271501-yjobthaj	75	93	'	'	''
cord-271501-yjobthaj	75	94	phosphate	phosphate	NN
cord-271501-yjobthaj	75	95	5'-phosphosulfate	5'-phosphosulfate	CD
cord-271501-yjobthaj	75	96	transporter	transporter	NN
cord-271501-yjobthaj	75	97	,	,	,
cord-271501-yjobthaj	75	98	a	a	DT
cord-271501-yjobthaj	75	99	homodimer	homodimer	NN
cord-271501-yjobthaj	75	100	within	within	IN
cord-271501-yjobthaj	75	101	the	the	DT
cord-271501-yjobthaj	75	102	membrane	membrane	NN
cord-271501-yjobthaj	75	103	A	a	DT
cord-271501-yjobthaj	75	104	monomeric	monomeric	JJ
cord-271501-yjobthaj	75	105	protein	protein	NN
cord-271501-yjobthaj	75	106	in	in	IN
cord-271501-yjobthaj	75	107	the	the	DT
cord-271501-yjobthaj	75	108	Golgi	Golgi	NNP
cord-271501-yjobthaj	75	109	membrane	membrane	NN
cord-271501-yjobthaj	76	1	catalyzes	catalyzes	NNP
cord-271501-yjobthaj	77	1	both	both	DT
cord-271501-yjobthaj	77	2	N	n	CD
cord-271501-yjobthaj	77	3	-	-	HYPH
cord-271501-yjobthaj	77	4	deacetylation	deacetylation	NN
cord-271501-yjobthaj	77	5	and	and	CC
cord-271501-yjobthaj	77	6	N	n	CD
cord-271501-yjobthaj	77	7	-	-	HYPH
cord-271501-yjobthaj	77	8	sulfation	sulfation	NN
cord-271501-yjobthaj	77	9	of	of	IN
cord-271501-yjobthaj	77	10	heparan	heparan	NN
cord-271501-yjobthaj	77	11	sulfate	sulfate	NN
cord-271501-yjobthaj	77	12	An	an	DT
cord-271501-yjobthaj	77	13	ATP	ATP	NNP
cord-271501-yjobthaj	77	14	transporter	transporter	NN
cord-271501-yjobthaj	77	15	it	-PRON-	PRP
cord-271501-yjobthaj	77	16	required	require	VBD
cord-271501-yjobthaj	77	17	for	for	IN
cord-271501-yjobthaj	77	18	protein	protein	NN
cord-271501-yjobthaj	77	19	translocation	translocation	NN
cord-271501-yjobthaj	77	20	into	into	IN
cord-271501-yjobthaj	77	21	the	the	DT
cord-271501-yjobthaj	77	22	yeast	yeast	NN
cord-271501-yjobthaj	77	23	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	77	24	reticulum	reticulum	NN
cord-271501-yjobthaj	77	25	Saclp	Saclp	NNP
cord-271501-yjobthaj	77	26	mediates	mediate	VBZ
cord-271501-yjobthaj	77	27	the	the	DT
cord-271501-yjobthaj	77	28	adenosine	adenosine	NN
cord-271501-yjobthaj	77	29	triphosphate	triphosphate	NN
cord-271501-yjobthaj	77	30	transport	transport	NN
cord-271501-yjobthaj	77	31	into	into	IN
cord-271501-yjobthaj	77	32	yeast	yeast	NN
cord-271501-yjobthaj	77	33	endoplasmic	endoplasmic	NN
cord-271501-yjobthaj	77	34	reticulum	reticulum	NN
cord-271501-yjobthaj	77	35	that	that	WDT
cord-271501-yjobthaj	77	36	is	be	VBZ
cord-271501-yjobthaj	77	37	required	require	VBN
cord-271501-yjobthaj	77	38	for	for	IN
cord-271501-yjobthaj	77	39	protein	protein	NN
cord-271501-yjobthaj	77	40	translocation	translocation	NN
cord-271501-yjobthaj	77	41	Complex	Complex	NNP
cord-271501-yjobthaj	77	42	asparagine	asparagine	NN
cord-271501-yjobthaj	77	43	-	-	HYPH
cord-271501-yjobthaj	77	44	linked	link	VBN
cord-271501-yjobthaj	77	45	oligosaccharides	oligosaccharide	NNS
cord-271501-yjobthaj	77	46	are	be	VBP
cord-271501-yjobthaj	77	47	required	require	VBN
cord-271501-yjobthaj	77	48	for	for	IN
cord-271501-yjobthaj	77	49	morphogenic	morphogenic	JJ
cord-271501-yjobthaj	77	50	events	event	NNS
cord-271501-yjobthaj	77	51	during	during	IN
cord-271501-yjobthaj	77	52	postimplantation	postimplantation	NN
cord-271501-yjobthaj	77	53	development	development	NN
cord-271501-yjobthaj	77	54	Reconstitution	Reconstitution	NNP
cord-271501-yjobthaj	77	55	of	of	IN
cord-271501-yjobthaj	77	56	Golgi	Golgi	NNP
cord-271501-yjobthaj	77	57	vesicle	vesicle	NN
cord-271501-yjobthaj	77	58	CMPsialic	cmpsialic	NN
cord-271501-yjobthaj	77	59	acid	acid	NN
cord-271501-yjobthaj	77	60	and	and	CC
cord-271501-yjobthaj	77	61	adenosine	adenosine	NN
cord-271501-yjobthaj	77	62	3	3	CD
cord-271501-yjobthaj	77	63	'	'	''
cord-271501-yjobthaj	77	64	phosphate	phosphate	NN
cord-271501-yjobthaj	77	65	5	5	CD
cord-271501-yjobthaj	77	66	'	'	POS
cord-271501-yjobthaj	77	67	phosphosulfate	phosphosulfate	NN
cord-271501-yjobthaj	77	68	transport	transport	NN
cord-271501-yjobthaj	77	69	into	into	IN
cord-271501-yjobthaj	77	70	proteoliposomes	proteoliposomes	NNP
cord-271501-yjobthaj	77	71	Characterization	characterization	NN
cord-271501-yjobthaj	77	72	of	of	IN
cord-271501-yjobthaj	77	73	the	the	DT
cord-271501-yjobthaj	77	74	Saccharomyces	Saccharomyces	NNP
cord-271501-yjobthaj	77	75	cerevisiae	cerevisiae	NN
cord-271501-yjobthaj	77	76	Golgi	Golgi	NNP
cord-271501-yjobthaj	77	77	complex	complex	JJ
cord-271501-yjobthaj	77	78	through	through	IN
cord-271501-yjobthaj	77	79	the	the	DT
cord-271501-yjobthaj	77	80	cell	cell	NN
cord-271501-yjobthaj	77	81	cycle	cycle	NN
cord-271501-yjobthaj	77	82	by	by	IN
cord-271501-yjobthaj	77	83	immunoelectronmicroscopy	immunoelectronmicroscopy	NNP
cord-271501-yjobthaj	77	84	Defect	Defect	NNP
cord-271501-yjobthaj	77	85	in	in	IN
cord-271501-yjobthaj	77	86	vitamin	vitamin	NN
cord-271501-yjobthaj	77	87	B	b	NN
cord-271501-yjobthaj	78	1	12	12	CD
cord-271501-yjobthaj	78	2	metabolism	metabolism	NN
cord-271501-yjobthaj	79	1	The	the	DT
cord-271501-yjobthaj	79	2	yeast	yeast	NN
cord-271501-yjobthaj	79	3	secretory	secretory	NN
cord-271501-yjobthaj	79	4	pathway	pathway	NN
cord-271501-yjobthaj	79	5	is	be	VBZ
cord-271501-yjobthaj	79	6	perturbed	perturb	VBN
cord-271501-yjobthaj	79	7	by	by	IN
cord-271501-yjobthaj	79	8	mutations	mutation	NNS
cord-271501-yjobthaj	79	9	in	in	IN
cord-271501-yjobthaj	79	10	PMR1	PMR1	NNP
cord-271501-yjobthaj	79	11	,	,	,
cord-271501-yjobthaj	79	12	a	a	DT
cord-271501-yjobthaj	79	13	member	member	NN
cord-271501-yjobthaj	79	14	of	of	IN
cord-271501-yjobthaj	79	15	a	a	DT
cord-271501-yjobthaj	79	16	Ca	Ca	NNP
cord-271501-yjobthaj	79	17	2	2	CD
cord-271501-yjobthaj	79	18	+	+	CD
cord-271501-yjobthaj	79	19	ATPase	ATPase	NNP
cord-271501-yjobthaj	79	20	family	family	NN
cord-271501-yjobthaj	80	1	The	the	DT
cord-271501-yjobthaj	80	2	Golgi	golgi	NN
cord-271501-yjobthaj	80	3	-	-	HYPH
cord-271501-yjobthaj	80	4	localization	localization	NN
cord-271501-yjobthaj	80	5	of	of	IN
cord-271501-yjobthaj	80	6	yeast	yeast	NN
cord-271501-yjobthaj	80	7	Emp47p	Emp47p	NNP
cord-271501-yjobthaj	80	8	depends	depend	VBZ
cord-271501-yjobthaj	80	9	on	on	IN
cord-271501-yjobthaj	80	10	its	-PRON-	PRP$
cord-271501-yjobthaj	80	11	di	di	NN
cord-271501-yjobthaj	80	12	-	-	HYPH
cord-271501-yjobthaj	80	13	lysine	lysine	JJ
cord-271501-yjobthaj	80	14	motif	motif	NN
cord-271501-yjobthaj	80	15	but	but	CC
cord-271501-yjobthaj	80	16	is	be	VBZ
cord-271501-yjobthaj	80	17	not	not	RB
cord-271501-yjobthaj	80	18	affected	affect	VBN
cord-271501-yjobthaj	80	19	by	by	IN
cord-271501-yjobthaj	80	20	the	the	DT
cord-271501-yjobthaj	80	21	retl-1	retl-1	NNP
cord-271501-yjobthaj	80	22	mutation	mutation	NN
cord-271501-yjobthaj	80	23	in	in	IN
cord-271501-yjobthaj	80	24	a	a	DT
cord-271501-yjobthaj	80	25	-	-	HYPH
cord-271501-yjobthaj	80	26	COP	cop	NN
cord-271501-yjobthaj	80	27	Transport	transport	NN
cord-271501-yjobthaj	80	28	of	of	IN
cord-271501-yjobthaj	80	29	sugar	sugar	NN
cord-271501-yjobthaj	80	30	nucleotides	nucleotide	NNS
cord-271501-yjobthaj	80	31	into	into	IN
cord-271501-yjobthaj	80	32	rat	rat	NN
cord-271501-yjobthaj	80	33	liver	liver	NN
cord-271501-yjobthaj	80	34	Golgi	Golgi	NNP
cord-271501-yjobthaj	80	35	:	:	:
cord-271501-yjobthaj	80	36	a	a	DT
cord-271501-yjobthaj	80	37	new	new	JJ
cord-271501-yjobthaj	80	38	Golgi	Golgi	NNP
cord-271501-yjobthaj	80	39	marker	marker	NN
cord-271501-yjobthaj	80	40	activity	activity	NN
cord-271501-yjobthaj	80	41	A	a	DT
cord-271501-yjobthaj	80	42	Golgi	Golgi	NNP
cord-271501-yjobthaj	80	43	retention	retention	NN
cord-271501-yjobthaj	80	44	signal	signal	NN
cord-271501-yjobthaj	80	45	in	in	IN
cord-271501-yjobthaj	80	46	a	a	DT
cord-271501-yjobthaj	80	47	membrane	membrane	NN
cord-271501-yjobthaj	80	48	-	-	HYPH
cord-271501-yjobthaj	80	49	spanning	span	VBG
cord-271501-yjobthaj	80	50	domain	domain	NN
cord-271501-yjobthaj	80	51	of	of	IN
cord-271501-yjobthaj	80	52	coronavirus	coronavirus	NN
cord-271501-yjobthaj	80	53	El	El	NNP
cord-271501-yjobthaj	80	54	protein	protein	NN
cord-271501-yjobthaj	80	55	Defective	defective	JJ
cord-271501-yjobthaj	80	56	lysosomal	lysosomal	JJ
cord-271501-yjobthaj	80	57	egress	egress	NN
cord-271501-yjobthaj	80	58	of	of	IN
cord-271501-yjobthaj	80	59	free	free	JJ
cord-271501-yjobthaj	80	60	sialic	sialic	NN
cord-271501-yjobthaj	80	61	acid	acid	NN
cord-271501-yjobthaj	80	62	(	(	-LRB-
cord-271501-yjobthaj	80	63	Nacetylneuraminic	Nacetylneuraminic	NNP
cord-271501-yjobthaj	80	64	acid	acid	NN
cord-271501-yjobthaj	80	65	)	)	-RRB-
cord-271501-yjobthaj	80	66	in	in	IN
cord-271501-yjobthaj	80	67	fibroblasts	fibroblast	NNS
cord-271501-yjobthaj	80	68	of	of	IN
cord-271501-yjobthaj	80	69	patients	patient	NNS
cord-271501-yjobthaj	80	70	with	with	IN
cord-271501-yjobthaj	80	71	infantile	infantile	JJ
cord-271501-yjobthaj	80	72	free	free	JJ
cord-271501-yjobthaj	80	73	sialic	sialic	JJ
cord-271501-yjobthaj	80	74	acid	acid	NN
cord-271501-yjobthaj	80	75	storage	storage	NN
cord-271501-yjobthaj	80	76	disease	disease	NN
cord-271501-yjobthaj	80	77	Transport	transport	NN
cord-271501-yjobthaj	80	78	of	of	IN
cord-271501-yjobthaj	80	79	UDP	udp	NN
cord-271501-yjobthaj	80	80	-	-	HYPH
cord-271501-yjobthaj	80	81	Galactose	galactose	NN
cord-271501-yjobthaj	80	82	into	into	IN
cord-271501-yjobthaj	80	83	the	the	DT
cord-271501-yjobthaj	80	84	Golgi	Golgi	NNP
cord-271501-yjobthaj	80	85	lumen	lumen	NN
cord-271501-yjobthaj	80	86	regulates	regulate	VBZ
cord-271501-yjobthaj	80	87	the	the	DT
cord-271501-yjobthaj	80	88	biosynthesis	biosynthesis	NN
cord-271501-yjobthaj	80	89	of	of	IN
cord-271501-yjobthaj	80	90	proteoglycans	proteoglycan	NNS
cord-271501-yjobthaj	81	1	The	the	DT
cord-271501-yjobthaj	81	2	KKXX	KKXX	NNP
cord-271501-yjobthaj	81	3	signal	signal	NN
cord-271501-yjobthaj	81	4	mediates	mediate	VBZ
cord-271501-yjobthaj	81	5	retrieval	retrieval	NN
cord-271501-yjobthaj	81	6	of	of	IN
cord-271501-yjobthaj	81	7	membrane	membrane	NN
cord-271501-yjobthaj	81	8	proteins	protein	NNS
cord-271501-yjobthaj	81	9	from	from	IN
cord-271501-yjobthaj	81	10	the	the	DT
cord-271501-yjobthaj	81	11	Golgi	Golgi	NNP
cord-271501-yjobthaj	81	12	to	to	IN
cord-271501-yjobthaj	81	13	the	the	DT
cord-271501-yjobthaj	81	14	ER	ER	NNP
cord-271501-yjobthaj	81	15	in	in	IN
cord-271501-yjobthaj	81	16	yeast	yeast	NN
cord-271501-yjobthaj	81	17	Eur	Eur	NNP
cord-271501-yjobthaj	81	18	UDP	UDP	NNP
cord-271501-yjobthaj	81	19	-	-	HYPH
cord-271501-yjobthaj	81	20	GlcNAc	glcnac	NN
cord-271501-yjobthaj	81	21	transport	transport	NN
cord-271501-yjobthaj	81	22	across	across	IN
cord-271501-yjobthaj	81	23	the	the	DT
cord-271501-yjobthaj	81	24	Golgi	Golgi	NNP
cord-271501-yjobthaj	81	25	membrane	membrane	NN
cord-271501-yjobthaj	81	26	:	:	:
cord-271501-yjobthaj	82	1	electroneutral	electroneutral	NNP
cord-271501-yjobthaj	82	2	exchange	exchange	NNP
cord-271501-yjobthaj	82	3	for	for	IN
cord-271501-yjobthaj	82	4	dianionic	dianionic	NNP
cord-271501-yjobthaj	82	5	UMP	UMP	NNP
cord-271501-yjobthaj	82	6	Acknowledgments	acknowledgment	NNS
cord-271501-yjobthaj	82	7	I	-PRON-	PRP
cord-271501-yjobthaj	82	8	thank	thank	VBP
cord-271501-yjobthaj	82	9	C.	C.	NNP
cord-271501-yjobthaj	82	10	Abeijon	Abeijon	NNP
cord-271501-yjobthaj	82	11	,	,	,
cord-271501-yjobthaj	82	12	J.	J.	NNP
cord-271501-yjobthaj	82	13	Baenziger	Baenziger	NNP
cord-271501-yjobthaj	82	14	,	,	,
cord-271501-yjobthaj	82	15	M.	M.	NNP
cord-271501-yjobthaj	82	16	Milla	Milla	NNP
cord-271501-yjobthaj	82	17	,	,	,
cord-271501-yjobthaj	82	18	and	and	CC
cord-271501-yjobthaj	82	19	E.	E.	NNP
cord-271501-yjobthaj	82	20	Mandon	Mandon	NNP
cord-271501-yjobthaj	82	21	for	for	IN
cord-271501-yjobthaj	82	22	helpful	helpful	JJ
cord-271501-yjobthaj	82	23	comments	comment	NNS
cord-271501-yjobthaj	82	24	,	,	,
cord-271501-yjobthaj	82	25	and	and	CC
cord-271501-yjobthaj	82	26	Annette	Annette	NNP
cord-271501-yjobthaj	82	27	Stratton	Stratton	NNP
cord-271501-yjobthaj	82	28	and	and	CC
cord-271501-yjobthaj	82	29	Karen	Karen	NNP
cord-271501-yjobthaj	82	30	Welch	Welch	NNP
cord-271501-yjobthaj	82	31	for	for	IN
cord-271501-yjobthaj	82	32	excellent	excellent	JJ
cord-271501-yjobthaj	82	33	secretarial	secretarial	JJ
cord-271501-yjobthaj	82	34	assistance	assistance	NN
cord-271501-yjobthaj	82	35	.	.	.
cord-271501-yjobthaj	83	1	The	the	DT
cord-271501-yjobthaj	83	2	work	work	NN
cord-271501-yjobthaj	83	3	in	in	IN
cord-271501-yjobthaj	83	4	my	-PRON-	PRP$
cord-271501-yjobthaj	83	5	laboratory	laboratory	NN
cord-271501-yjobthaj	83	6	was	be	VBD
cord-271501-yjobthaj	83	7	supported	support	VBN
cord-271501-yjobthaj	83	8	by	by	IN
cord-271501-yjobthaj	83	9	Grants	Grants	NNPS
cord-271501-yjobthaj	83	10	NTH	NTH	NNP
cord-271501-yjobthaj	83	11	30365	30365	CD
cord-271501-yjobthaj	83	12	and	and	CC
cord-271501-yjobthaj	83	13	34396	34396	CD
cord-271501-yjobthaj	83	14	from	from	IN
cord-271501-yjobthaj	83	15	the	the	DT
cord-271501-yjobthaj	83	16	National	National	NNP
cord-271501-yjobthaj	83	17	Institute	Institute	NNP
cord-271501-yjobthaj	83	18	of	of	IN
cord-271501-yjobthaj	83	19	General	General	NNP
cord-271501-yjobthaj	83	20	Medical	Medical	NNP
cord-271501-yjobthaj	83	21	Sciences	Sciences	NNPS
cord-271501-yjobthaj	83	22	.	.	.